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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV11l16f
         (613 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ...   195   9e-50
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas...   195   9e-50
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro...   195   9e-50
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.             195   9e-50
BC101829-1|AAI01830.1|  469|Homo sapiens cytosolic beta-glucosid...   170   4e-42
AK222963-1|BAD96683.1|  469|Homo sapiens cytosolic beta-glucosid...   170   4e-42
AJ278964-1|CAC08178.1|  469|Homo sapiens cytosolic beta-glucosid...   170   4e-42
AF323990-1|AAL37305.1|  469|Homo sapiens cytosolic beta-glucosid...   170   4e-42
AB017913-1|BAB18741.1|  469|Homo sapiens cytosolic beta-glucosid...   170   4e-42
AF317840-1|AAG39217.1|  469|Homo sapiens cytosolic beta-glucosid...   169   7e-42
AY358729-1|AAQ89091.1|  567|Homo sapiens KPVW3022 protein.            164   3e-40
Z92540-2|CAC94767.1|  273|Homo sapiens 179I15.1 (klotho) protein.     159   7e-39
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.              159   7e-39
AB009667-2|BAA24941.1|  549|Homo sapiens Klotho protein (KL) pro...   159   7e-39
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro...   159   7e-39
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.              159   7e-39
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.         134   2e-31
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.         134   2e-31
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei...   134   2e-31
BC109377-1|AAI09378.1|  162|Homo sapiens GBA3 protein protein.         99   6e-21
BC029362-1|AAH29362.1|  162|Homo sapiens GBA3 protein protein.         99   6e-21
BC070188-1|AAH70188.1|  162|Homo sapiens GBA3 protein protein.         99   1e-20
Z84483-1|CAC94773.1|  739|Homo sapiens 46H23.1 (Klotho) protein.       70   7e-12
BT007435-1|AAP36103.1|  441|Homo sapiens G protein-coupled recep...    32   1.8  
BC125081-1|AAI25082.1|  486|Homo sapiens G protein-coupled recep...    32   1.8  
BC125080-1|AAI25081.1|  486|Homo sapiens G protein-coupled recep...    32   1.8  
BC110848-1|AAI10849.1|  486|Homo sapiens G protein-coupled recep...    32   1.8  
BC016860-1|AAH16860.2|  448|Homo sapiens GPRC5C protein protein.       32   1.8  
AK075397-1|BAC11595.1|  441|Homo sapiens protein ( Homo sapiens ...    32   1.8  
AJ276102-1|CAC00633.1|  441|Homo sapiens GPRC5C protein.               32   1.8  
AF207989-1|AAF72870.1|  441|Homo sapiens orphan G-protein couple...    32   1.8  
BC034469-1|AAH34469.1|  849|Homo sapiens coiled-coil domain cont...    30   5.6  
AK001648-1|BAA91808.1|  849|Homo sapiens protein ( Homo sapiens ...    30   5.6  
AK055382-1|BAB70911.1|  123|Homo sapiens protein ( Homo sapiens ...    29   9.8  
AK055234-1|BAB70883.1|  123|Homo sapiens protein ( Homo sapiens ...    29   9.8  

>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
            lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
          Length = 1927

 Score =  195 bits (476), Expect = 9e-50
 Identities = 86/155 (55%), Positives = 111/155 (71%)
 Frame = +3

Query: 84   FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
            F DDFL G ++++YQIEGAW+ DGKG +IWD  TH   + VKD +TGDIA +SYH ++ D
Sbjct: 903  FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 264  VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
            + M+R L +  YRFS+SWSRI P+G  + IN  GVDYYNRLIN ++   I PM+TLFHWD
Sbjct: 963  LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022

Query: 444  LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            LPQ LQ++GG+ NP     F+ YA   +  FGDRV
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRV 1057



 Score =  174 bits (423), Expect = 2e-43
 Identities = 76/156 (48%), Positives = 108/156 (69%)
 Frame = +3

Query: 81   RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
            RFP+ F+   A+A+YQIEGAW  DGKG +IWD  +H  P  V++ + GD+A +SYH +  
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434

Query: 261  DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
            D+  ++ LG+  YRFS+SWSRILP G    INEAG++YY RLI+ +L   I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494

Query: 441  DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            DLPQ LQ++GG+ N      F++YA V++   GD+V
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKV 1530



 Score =  148 bits (359), Expect = 1e-35
 Identities = 72/159 (45%), Positives = 98/159 (61%), Gaps = 1/159 (0%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
           Q  FP+ FL G +T ++ +EG W E G+G +IWD      P    +G +T ++A++SYH 
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435

Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
           V  DV ++  L   VY+FS+SWSRI P G  +  +  GV YYN+LI+ +   GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495

Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           FHWDLPQ LQ+ GG+ N      F DYA   ++ FGDRV
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRV 534



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
 Frame = +3

Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
           Y+  LSW+++LP+G     +E  V  Y RL+  +    + PM+ L H  LP   L+    
Sbjct: 87  YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146

Query: 474 FANPLASIWFEDYARVVYTNFGDRV 548
           FA+      F DYA   + +FGD V
Sbjct: 147 FAD-----LFADYATFAFHSFGDLV 166



 Score = 32.7 bits (71), Expect = 1.0
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +1

Query: 550  KHWITINEPREICYEGYG 603
            K WIT+NEP  I Y+GYG
Sbjct: 1531 KFWITLNEPFVIAYQGYG 1548


>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
            protein.
          Length = 1927

 Score =  195 bits (476), Expect = 9e-50
 Identities = 86/155 (55%), Positives = 111/155 (71%)
 Frame = +3

Query: 84   FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
            F DDFL G ++++YQIEGAW+ DGKG +IWD  TH   + VKD +TGDIA +SYH ++ D
Sbjct: 903  FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 264  VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
            + M+R L +  YRFS+SWSRI P+G  + IN  GVDYYNRLIN ++   I PM+TLFHWD
Sbjct: 963  LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022

Query: 444  LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            LPQ LQ++GG+ NP     F+ YA   +  FGDRV
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRV 1057



 Score =  174 bits (423), Expect = 2e-43
 Identities = 76/156 (48%), Positives = 108/156 (69%)
 Frame = +3

Query: 81   RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
            RFP+ F+   A+A+YQIEGAW  DGKG +IWD  +H  P  V++ + GD+A +SYH +  
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434

Query: 261  DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
            D+  ++ LG+  YRFS+SWSRILP G    INEAG++YY RLI+ +L   I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494

Query: 441  DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            DLPQ LQ++GG+ N      F++YA V++   GD+V
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKV 1530



 Score =  148 bits (359), Expect = 1e-35
 Identities = 72/159 (45%), Positives = 98/159 (61%), Gaps = 1/159 (0%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
           Q  FP+ FL G +T ++ +EG W E G+G +IWD      P    +G +T ++A++SYH 
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435

Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
           V  DV ++  L   VY+FS+SWSRI P G  +  +  GV YYN+LI+ +   GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495

Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           FHWDLPQ LQ+ GG+ N      F DYA   ++ FGDRV
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRV 534



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
 Frame = +3

Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
           Y+  LSW+++LP+G     +E  V  Y RL+  +    + PM+ L H  LP   L+    
Sbjct: 87  YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146

Query: 474 FANPLASIWFEDYARVVYTNFGDRV 548
           FA+      F DYA   + +FGD V
Sbjct: 147 FAD-----LFADYATFAFHSFGDLV 166



 Score = 32.7 bits (71), Expect = 1.0
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +1

Query: 550  KHWITINEPREICYEGYG 603
            K WIT+NEP  I Y+GYG
Sbjct: 1531 KFWITLNEPFVIAYQGYG 1548


>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
           hydrolase-1 protein.
          Length = 1003

 Score =  195 bits (476), Expect = 9e-50
 Identities = 86/155 (55%), Positives = 111/155 (71%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           F DDFL G ++++YQIEGAW+ DGKG +IWD  TH   + VKD +TGDIA +SYH ++ D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           + M+R L +  YRFS+SWSRI P+G  + IN  GVDYYNRLIN ++   I PM+TLFHWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454

Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           LPQ LQ++GG+ NP     F+ YA   +  FGDRV
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRV 489



 Score =  174 bits (423), Expect = 2e-43
 Identities = 76/156 (48%), Positives = 108/156 (69%)
 Frame = +3

Query: 81   RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
            RFP+ F+   A+A+YQIEGAW  DGKG +IWD  +H  P  V++ + GD+A +SYH +  
Sbjct: 808  RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 866

Query: 261  DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
            D+  ++ LG+  YRFS+SWSRILP G    INEAG++YY RLI+ +L   I P +T++HW
Sbjct: 867  DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926

Query: 441  DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            DLPQ LQ++GG+ N      F++YA V++   GD+V
Sbjct: 927  DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKV 962



 Score = 32.7 bits (71), Expect = 1.0
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +1

Query: 550  KHWITINEPREICYEGYG 603
            K WIT+NEP  I Y+GYG
Sbjct: 963  KFWITLNEPFVIAYQGYG 980


>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
          Length = 1927

 Score =  195 bits (476), Expect = 9e-50
 Identities = 86/155 (55%), Positives = 111/155 (71%)
 Frame = +3

Query: 84   FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
            F DDFL G ++++YQIEGAW+ DGKG +IWD  TH   + VKD +TGDIA +SYH ++ D
Sbjct: 903  FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 264  VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
            + M+R L +  YRFS+SWSRI P+G  + IN  GVDYYNRLIN ++   I PM+TLFHWD
Sbjct: 963  LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022

Query: 444  LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            LPQ LQ++GG+ NP     F+ YA   +  FGDRV
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRV 1057



 Score =  174 bits (423), Expect = 2e-43
 Identities = 76/156 (48%), Positives = 108/156 (69%)
 Frame = +3

Query: 81   RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
            RFP+ F+   A+A+YQIEGAW  DGKG +IWD  +H  P  V++ + GD+A +SYH +  
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434

Query: 261  DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
            D+  ++ LG+  YRFS+SWSRILP G    INEAG++YY RLI+ +L   I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494

Query: 441  DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            DLPQ LQ++GG+ N      F++YA V++   GD+V
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKV 1530



 Score =  148 bits (359), Expect = 1e-35
 Identities = 72/159 (45%), Positives = 98/159 (61%), Gaps = 1/159 (0%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
           Q  FP+ FL G +T ++ +EG W E G+G +IWD      P    +G +T ++A++SYH 
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435

Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
           V  DV ++  L   VY+FS+SWSRI P G  +  +  GV YYN+LI+ +   GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495

Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           FHWDLPQ LQ+ GG+ N      F DYA   ++ FGDRV
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRV 534



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
 Frame = +3

Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
           Y+  LSW+++LP+G     +E  V  Y RL+  +    + PM+ L H  LP   L+    
Sbjct: 87  YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146

Query: 474 FANPLASIWFEDYARVVYTNFGDRV 548
           FA+      F DYA   + +FGD V
Sbjct: 147 FAD-----LFADYATFAFHSFGDLV 166



 Score = 32.7 bits (71), Expect = 1.0
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +1

Query: 550  KHWITINEPREICYEGYG 603
            K WIT+NEP  I Y+GYG
Sbjct: 1531 KFWITLNEPFVIAYQGYG 1548


>BC101829-1|AAI01830.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  170 bits (413), Expect = 4e-42
 Identities = 74/155 (47%), Positives = 105/155 (67%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           ++ +++LGL  YRFSLSWSR+LP G    IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           LPQ L++ GG+ +      F+ YA+  ++ FGDRV
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRV 157


>AK222963-1|BAD96683.1|  469|Homo sapiens cytosolic beta-glucosidase
           variant protein.
          Length = 469

 Score =  170 bits (413), Expect = 4e-42
 Identities = 74/155 (47%), Positives = 105/155 (67%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           ++ +++LGL  YRFSLSWSR+LP G    IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           LPQ L++ GG+ +      F+ YA+  ++ FGDRV
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRV 157


>AJ278964-1|CAC08178.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  170 bits (413), Expect = 4e-42
 Identities = 74/155 (47%), Positives = 105/155 (67%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           ++ +++LGL  YRFSLSWSR+LP G    IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           LPQ L++ GG+ +      F+ YA+  ++ FGDRV
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRV 157


>AF323990-1|AAL37305.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  170 bits (413), Expect = 4e-42
 Identities = 74/155 (47%), Positives = 105/155 (67%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           ++ +++LGL  YRFSLSWSR+LP G    IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           LPQ L++ GG+ +      F+ YA+  ++ FGDRV
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRV 157


>AB017913-1|BAB18741.1|  469|Homo sapiens cytosolic
           beta-glucosidase-like protein-1 protein.
          Length = 469

 Score =  170 bits (413), Expect = 4e-42
 Identities = 74/155 (47%), Positives = 105/155 (67%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           ++ +++LGL  YRFSLSWSR+LP G    IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           LPQ L++ GG+ +      F+ YA+  ++ FGDRV
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRV 157


>AF317840-1|AAG39217.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  169 bits (411), Expect = 7e-42
 Identities = 74/155 (47%), Positives = 105/155 (67%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           ++ +++LGL  YRFSLSWSR+LP G    IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           LPQ L++ GG+ +      F+ YA+  ++ FGDRV
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRV 157


>AY358729-1|AAQ89091.1|  567|Homo sapiens KPVW3022 protein.
          Length = 567

 Score =  164 bits (398), Expect = 3e-40
 Identities = 72/157 (45%), Positives = 107/157 (68%), Gaps = 2/157 (1%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F  G  +++YQ EGAW++DGKG +IWD  TH+    V    T D+A + Y+ V+ D
Sbjct: 37  FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGF-ANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
           + ++REL ++ YRFSLSW R+LP+G  A ++N+ G+++Y+ LI+ +L   ITP++TL HW
Sbjct: 97  IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156

Query: 441 DLPQKLQ-ELGGFANPLASIWFEDYARVVYTNFGDRV 548
           DLPQ LQ + GG+ N   + +F DYA + +  FGDRV
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRV 193



 Score = 29.9 bits (64), Expect = 7.4
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 550 KHWITINEPREICYEGYGSVH 612
           KHWIT ++PR +  +GY + H
Sbjct: 194 KHWITFSDPRAMAEKGYETGH 214


>Z92540-2|CAC94767.1|  273|Homo sapiens 179I15.1 (klotho) protein.
          Length = 273

 Score =  159 bits (386), Expect = 7e-39
 Identities = 77/174 (44%), Positives = 109/174 (62%), Gaps = 16/174 (9%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
           Q  FPD FL    +A+YQ EG W + GKG +IWD  TH+  A   D              
Sbjct: 58  QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117

Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
             +TGD+A++SY+NV RD E +RELG+  YRFS+SW+R+LP+G A   N  G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177

Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
             + + G+ P++TL+HWDLPQ+LQ+  GG+AN   +  F DYA + + +FG +V
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQV 231


>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
          Length = 1012

 Score =  159 bits (386), Expect = 7e-39
 Identities = 77/174 (44%), Positives = 109/174 (62%), Gaps = 16/174 (9%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
           Q  FPD FL    +A+YQ EG W + GKG +IWD  TH+  A   D              
Sbjct: 58  QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117

Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
             +TGD+A++SY+NV RD E +RELG+  YRFS+SW+R+LP+G A   N  G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177

Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
             + + G+ P++TL+HWDLPQ+LQ+  GG+AN   +  F DYA + + +FG +V
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQV 231



 Score = 69.7 bits (163), Expect = 7e-12
 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 10/165 (6%)
 Frame = +3

Query: 84   FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
            FP DF  G      Q++   ++       +WD   H++   +K          SY     
Sbjct: 519  FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576

Query: 249  NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
             ++  + +++E+ +  +RFSL W+ ILP G  +++N   + YY  + +E+++  ITP++ 
Sbjct: 577  AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636

Query: 429  LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            L+     +  LP+ L   G + NP  ++ F +YAR+ +   G  V
Sbjct: 637  LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHV 681


>AB009667-2|BAA24941.1|  549|Homo sapiens Klotho protein (KL)
           protein.
          Length = 549

 Score =  159 bits (386), Expect = 7e-39
 Identities = 77/174 (44%), Positives = 109/174 (62%), Gaps = 16/174 (9%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
           Q  FPD FL    +A+YQ EG W + GKG +IWD  TH+  A   D              
Sbjct: 58  QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117

Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
             +TGD+A++SY+NV RD E +RELG+  YRFS+SW+R+LP+G A   N  G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177

Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
             + + G+ P++TL+HWDLPQ+LQ+  GG+AN   +  F DYA + + +FG +V
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQV 231


>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
           protein.
          Length = 1012

 Score =  159 bits (386), Expect = 7e-39
 Identities = 77/174 (44%), Positives = 109/174 (62%), Gaps = 16/174 (9%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
           Q  FPD FL    +A+YQ EG W + GKG +IWD  TH+  A   D              
Sbjct: 58  QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117

Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
             +TGD+A++SY+NV RD E +RELG+  YRFS+SW+R+LP+G A   N  G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177

Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
             + + G+ P++TL+HWDLPQ+LQ+  GG+AN   +  F DYA + + +FG +V
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQV 231



 Score = 69.7 bits (163), Expect = 7e-12
 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 10/165 (6%)
 Frame = +3

Query: 84   FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
            FP DF  G      Q++   ++       +WD   H++   +K          SY     
Sbjct: 519  FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576

Query: 249  NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
             ++  + +++E+ +  +RFSL W+ ILP G  +++N   + YY  + +E+++  ITP++ 
Sbjct: 577  AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636

Query: 429  LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            L+     +  LP+ L   G + NP  ++ F +YAR+ +   G  V
Sbjct: 637  LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHV 681


>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
          Length = 1012

 Score =  159 bits (386), Expect = 7e-39
 Identities = 77/174 (44%), Positives = 109/174 (62%), Gaps = 16/174 (9%)
 Frame = +3

Query: 75  QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
           Q  FPD FL    +A+YQ EG W + GKG +IWD  TH+  A   D              
Sbjct: 58  QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117

Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
             +TGD+A++SY+NV RD E +RELG+  YRFS+SW+R+LP+G A   N  G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177

Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
             + + G+ P++TL+HWDLPQ+LQ+  GG+AN   +  F DYA + + +FG +V
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQV 231



 Score = 69.7 bits (163), Expect = 7e-12
 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 10/165 (6%)
 Frame = +3

Query: 84   FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
            FP DF  G      Q++   ++       +WD   H++   +K          SY     
Sbjct: 519  FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576

Query: 249  NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
             ++  + +++E+ +  +RFSL W+ ILP G  +++N   + YY  + +E+++  ITP++ 
Sbjct: 577  AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636

Query: 429  LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
            L+     +  LP+ L   G + NP  ++ F +YAR+ +   G  V
Sbjct: 637  LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHV 681


>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
          Length = 1044

 Score =  134 bits (324), Expect = 2e-31
 Identities = 61/156 (39%), Positives = 96/156 (61%), Gaps = 1/156 (0%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP +F  G  T + Q+EG+W +DGKG +IWD+  H +   +K+ S+ + +++SY  +E+D
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           +  +  +G+  Y+FS+SW R+ P G     N  G+ YY+ L++ ++   I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197

Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
           LP  LQE  GG+ N      F DYA   +  FGDRV
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRV 233



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/105 (33%), Positives = 61/105 (58%), Gaps = 5/105 (4%)
 Frame = +3

Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
           N+++ +EM+  + +  YRF+L W+ +LP+G  + +N   + YY  +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640

Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           L+     H  LP+ L    G+ NP  +  F+ YA + +   GD V
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLV 685


>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
          Length = 1044

 Score =  134 bits (324), Expect = 2e-31
 Identities = 61/156 (39%), Positives = 96/156 (61%), Gaps = 1/156 (0%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP +F  G  T + Q+EG+W +DGKG +IWD+  H +   +K+ S+ + +++SY  +E+D
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           +  +  +G+  Y+FS+SW R+ P G     N  G+ YY+ L++ ++   I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197

Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
           LP  LQE  GG+ N      F DYA   +  FGDRV
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRV 233



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/105 (33%), Positives = 61/105 (58%), Gaps = 5/105 (4%)
 Frame = +3

Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
           N+++ +EM+  + +  YRF+L W+ +LP+G  + +N   + YY  +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640

Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           L+     H  LP+ L    G+ NP  +  F+ YA + +   GD V
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLV 685


>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
           protein.
          Length = 1044

 Score =  134 bits (324), Expect = 2e-31
 Identities = 61/156 (39%), Positives = 96/156 (61%), Gaps = 1/156 (0%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP +F  G  T + Q+EG+W +DGKG +IWD+  H +   +K+ S+ + +++SY  +E+D
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
           +  +  +G+  Y+FS+SW R+ P G     N  G+ YY+ L++ ++   I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197

Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRV 548
           LP  LQE  GG+ N      F DYA   +  FGDRV
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRV 233



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/105 (33%), Positives = 61/105 (58%), Gaps = 5/105 (4%)
 Frame = +3

Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
           N+++ +EM+  + +  YRF+L W+ +LP+G  + +N   + YY  +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640

Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           L+     H  LP+ L    G+ NP  +  F+ YA + +   GD V
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLV 685


>BC109377-1|AAI09378.1|  162|Homo sapiens GBA3 protein protein.
          Length = 162

 Score =   99 bits (238), Expect = 6e-21
 Identities = 45/95 (47%), Positives = 58/95 (61%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
           ++ +++LGL  YRFSLSWSR+LP G    IN+  +
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97


>BC029362-1|AAH29362.1|  162|Homo sapiens GBA3 protein protein.
          Length = 162

 Score =   99 bits (238), Expect = 6e-21
 Identities = 45/95 (47%), Positives = 58/95 (61%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
           ++ +++LGL  YRFSLSWSR+LP G    IN+  +
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97


>BC070188-1|AAH70188.1|  162|Homo sapiens GBA3 protein protein.
          Length = 162

 Score = 99.1 bits (236), Expect = 1e-20
 Identities = 45/95 (47%), Positives = 58/95 (61%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
           FP  F    ATA+YQ+EG W+ DGKG  +WD  TH     V    TGD+A  SY   E D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
           ++ +++LGL  YRFSLSWSR+LP G    IN+  +
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97


>Z84483-1|CAC94773.1|  739|Homo sapiens 46H23.1 (Klotho) protein.
          Length = 739

 Score = 69.7 bits (163), Expect = 7e-12
 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 10/165 (6%)
 Frame = +3

Query: 84  FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
           FP DF  G      Q++   ++       +WD   H++   +K          SY     
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 303

Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
            ++  + +++E+ +  +RFSL W+ ILP G  +++N   + YY  + +E+++  ITP++ 
Sbjct: 304 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 363

Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRV 548
           L+     +  LP+ L   G + NP  ++ F +YAR+ +   G  V
Sbjct: 364 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHV 408


>BT007435-1|AAP36103.1|  441|Homo sapiens G protein-coupled
           receptor, family C, group 5, member C protein.
          Length = 441

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438


>BC125081-1|AAI25082.1|  486|Homo sapiens G protein-coupled
           receptor, family C, group 5, member C protein.
          Length = 486

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483


>BC125080-1|AAI25081.1|  486|Homo sapiens G protein-coupled
           receptor, family C, group 5, member C protein.
          Length = 486

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483


>BC110848-1|AAI10849.1|  486|Homo sapiens G protein-coupled
           receptor, family C, group 5, member C protein.
          Length = 486

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483


>BC016860-1|AAH16860.2|  448|Homo sapiens GPRC5C protein protein.
          Length = 448

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 395 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 445


>AK075397-1|BAC11595.1|  441|Homo sapiens protein ( Homo sapiens
           cDNA PSEC0087 fis, clone PLACE1001022, highly similar to
           G protein-coupled receptor, family C, group 5, member C
           isoform ).
          Length = 441

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438


>AJ276102-1|CAC00633.1|  441|Homo sapiens GPRC5C protein.
          Length = 441

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438


>AF207989-1|AAF72870.1|  441|Homo sapiens orphan G-protein coupled
           receptor protein.
          Length = 441

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +3

Query: 93  DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
           D ++  ATA+ Q+ G+ N   + E+++   +H      KDG    +  N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438


>BC034469-1|AAH34469.1|  849|Homo sapiens coiled-coil domain
           containing 87 protein.
          Length = 849

 Score = 30.3 bits (65), Expect = 5.6
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +1

Query: 67  PSSREGFRMTSSSGLPPPPTR 129
           PS REG+R+    GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333


>AK001648-1|BAA91808.1|  849|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10786 fis, clone NT2RP4000480. ).
          Length = 849

 Score = 30.3 bits (65), Expect = 5.6
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +1

Query: 67  PSSREGFRMTSSSGLPPPPTR 129
           PS REG+R+    GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333


>AK055382-1|BAB70911.1|  123|Homo sapiens protein ( Homo sapiens
           cDNA FLJ30820 fis, clone FEBRA2001591. ).
          Length = 123

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 12/26 (46%), Positives = 14/26 (53%)
 Frame = +1

Query: 46  CAAPHYRPSSREGFRMTSSSGLPPPP 123
           C+  HYRP   EG +  S  GL  PP
Sbjct: 14  CSLSHYRPGGLEGKKWFSGPGLRHPP 39


>AK055234-1|BAB70883.1|  123|Homo sapiens protein ( Homo sapiens
           cDNA FLJ30672 fis, clone FCBBF1000691. ).
          Length = 123

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 12/26 (46%), Positives = 14/26 (53%)
 Frame = +1

Query: 46  CAAPHYRPSSREGFRMTSSSGLPPPP 123
           C+  HYRP   EG +  S  GL  PP
Sbjct: 14  CSLSHYRPGGLEGKKWFSGPGLRHPP 39


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 86,200,574
Number of Sequences: 237096
Number of extensions: 1662033
Number of successful extensions: 4336
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 4075
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4306
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6522878360
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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