Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV11f13r
(732 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 235 1e-60
UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891... 228 1e-58
UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep: ... 226 4e-58
UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-P... 224 2e-57
UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4; ... 224 2e-57
UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1; ... 188 2e-46
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 181 1e-44
UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid dehydrog... 181 2e-44
UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, wh... 173 5e-42
UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=... 167 2e-40
UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid dehydrog... 163 3e-39
UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto... 161 1e-38
UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 159 6e-38
UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 157 3e-37
UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, ... 157 3e-37
UniRef50_Q4Y3F8 Cluster: Branched-chain alpha keto-acid dehydrog... 144 1e-33
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 124 3e-27
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 122 9e-27
UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 118 1e-25
UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component sub... 118 1e-25
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 118 2e-25
UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 compo... 117 3e-25
UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n... 116 5e-25
UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1, tran... 115 1e-24
UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component sub... 112 7e-24
UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component sub... 112 1e-23
UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 109 7e-23
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 105 8e-22
UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 105 1e-21
UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2; Arthrobact... 104 3e-21
UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit... 102 1e-20
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 101 2e-20
UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 100 3e-20
UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16; Mycobacte... 100 4e-20
UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,... 99 1e-19
UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 99 1e-19
UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n... 98 2e-19
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 97 4e-19
UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid dehydrog... 96 9e-19
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 95 1e-18
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 95 2e-18
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 95 2e-18
UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, al... 93 5e-18
UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 93 6e-18
UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1 compo... 93 8e-18
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 92 1e-17
UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcu... 92 1e-17
UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto... 92 1e-17
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 92 1e-17
UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 92 1e-17
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 91 3e-17
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 91 3e-17
UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 91 3e-17
UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;... 91 3e-17
UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component sub... 89 1e-16
UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alp... 89 1e-16
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 88 2e-16
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 87 4e-16
UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 86 1e-15
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 86 1e-15
UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2; Roseiflexu... 85 2e-15
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 84 4e-15
UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11; Actinomyc... 83 7e-15
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 83 7e-15
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 83 9e-15
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 83 9e-15
UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component sub... 82 2e-14
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 81 4e-14
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 80 5e-14
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 79 8e-14
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 79 1e-13
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 77 3e-13
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 77 3e-13
UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 77 3e-13
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 77 6e-13
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 76 1e-12
UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 74 3e-12
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 74 3e-12
UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component, al... 73 7e-12
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 73 7e-12
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 73 1e-11
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 73 1e-11
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 71 4e-11
UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alp... 71 4e-11
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 70 5e-11
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 70 7e-11
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 70 7e-11
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 69 1e-10
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 69 1e-10
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 69 2e-10
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 68 2e-10
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 68 2e-10
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 68 2e-10
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 68 3e-10
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 68 3e-10
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 67 5e-10
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 67 5e-10
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 66 8e-10
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 66 1e-09
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 65 1e-09
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 65 2e-09
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 65 2e-09
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 65 2e-09
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 64 4e-09
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 63 6e-09
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 63 8e-09
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 62 1e-08
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 62 2e-08
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 61 2e-08
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 61 2e-08
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 60 4e-08
UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1; R... 60 4e-08
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 60 4e-08
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 60 5e-08
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 60 5e-08
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 60 7e-08
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 59 1e-07
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 58 2e-07
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 58 2e-07
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 58 3e-07
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 57 4e-07
UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3; Bacte... 57 4e-07
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 57 4e-07
UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3; Actin... 57 5e-07
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 56 1e-06
UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha s... 55 2e-06
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 55 2e-06
UniRef50_Q6MP90 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 54 4e-06
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 54 4e-06
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 54 4e-06
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 54 5e-06
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 52 1e-05
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 51 3e-05
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 50 4e-05
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 50 4e-05
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 50 6e-05
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 50 6e-05
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 50 8e-05
UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alp... 50 8e-05
UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomon... 50 8e-05
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 49 1e-04
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 49 1e-04
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 48 2e-04
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 47 5e-04
UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5... 47 5e-04
UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter viola... 46 7e-04
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 46 7e-04
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12; Bacteria|... 44 0.004
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 42 0.012
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 42 0.016
UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1; Proch... 41 0.027
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig... 41 0.027
UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1; Novos... 41 0.036
UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1 comp... 40 0.083
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 39 0.11
UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA... 39 0.15
UniRef50_A5KBR9 Cluster: Nucleosomal binding protein 1, putative... 38 0.19
UniRef50_Q0UJ30 Cluster: Putative uncharacterized protein; n=2; ... 38 0.25
UniRef50_Q234R7 Cluster: Viral A-type inclusion protein repeat c... 38 0.33
UniRef50_A3HUN2 Cluster: Putative uncharacterized protein; n=1; ... 37 0.44
UniRef50_Q9N437 Cluster: Putative uncharacterized protein; n=2; ... 37 0.44
UniRef50_UPI0000DB76E3 Cluster: PREDICTED: similar to Posterior ... 37 0.59
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 37 0.59
UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7; Mycoba... 37 0.59
UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 37 0.59
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 37 0.59
UniRef50_Q9VR26 Cluster: CG3294-PA, isoform A; n=4; Sophophora|R... 36 0.77
UniRef50_A7SQM2 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.0
UniRef50_Q2H0S6 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-... 35 1.8
UniRef50_Q2BCS0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_A6DI60 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; L... 35 1.8
UniRef50_Q9P1H6 Cluster: PRO1410; n=1; Homo sapiens|Rep: PRO1410... 35 1.8
UniRef50_Q89YV4 Cluster: DNA modification methylase; n=1; Bacter... 35 2.4
UniRef50_A0EER6 Cluster: Chromosome undetermined scaffold_92, wh... 35 2.4
UniRef50_UPI0000F20063 Cluster: PREDICTED: similar to LOC560949 ... 34 3.1
UniRef50_UPI0000E49DA7 Cluster: PREDICTED: similar to Wu:fc43a05... 34 3.1
UniRef50_UPI0000D55AB7 Cluster: PREDICTED: similar to CG7719-PA;... 34 3.1
UniRef50_UPI00004983CC Cluster: chromosome partition protein; n=... 34 3.1
UniRef50_UPI00001626D4 Cluster: unknown protein; n=1; Arabidopsi... 34 3.1
UniRef50_Q5M3M3 Cluster: Type II restriction-modification system... 34 3.1
UniRef50_Q54BL5 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_Q28WZ4 Cluster: GA15715-PA; n=1; Drosophila pseudoobscu... 34 3.1
UniRef50_A2DCE1 Cluster: Putative uncharacterized protein; n=2; ... 34 3.1
UniRef50_A2QWE0 Cluster: Putative uncharacterized protein; n=5; ... 34 3.1
UniRef50_Q8XHG9 Cluster: Putative uncharacterized protein CPE251... 34 4.1
UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily ... 34 4.1
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 34 4.1
UniRef50_Q871C9 Cluster: Related to heat shock protein dnaJ; n=1... 34 4.1
UniRef50_A5DLJ8 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 34 4.1
UniRef50_UPI00006CD2BD Cluster: Viral A-type inclusion protein r... 33 5.5
UniRef50_Q2W161 Cluster: Putative uncharacterized protein; n=2; ... 33 5.5
UniRef50_O51650 Cluster: Putative uncharacterized protein BB0707... 33 5.5
UniRef50_Q9XH27 Cluster: F10A2.9 protein; n=1; Arabidopsis thali... 33 5.5
UniRef50_Q0DWE7 Cluster: Os02g0818500 protein; n=2; Oryza sativa... 33 5.5
UniRef50_UPI00004986FF Cluster: conserved hypothetical protein; ... 33 7.2
UniRef50_Q914N0 Cluster: ORF1; n=8; Torque teno virus|Rep: ORF1 ... 33 7.2
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 33 7.2
UniRef50_Q2GD66 Cluster: Transketolase, insertion; n=1; Neoricke... 33 7.2
UniRef50_Q05WA5 Cluster: Putative dape protein; n=1; Synechococc... 33 7.2
UniRef50_A1ZRD4 Cluster: Tetratricopeptide repeat domain protein... 33 7.2
UniRef50_A0HIT5 Cluster: Phage-related protein predicted endonuc... 33 7.2
UniRef50_Q61F95 Cluster: Putative uncharacterized protein CBG117... 33 7.2
UniRef50_Q23QN9 Cluster: Dynein heavy chain family protein; n=4;... 33 7.2
UniRef50_A5K5E5 Cluster: Tryptophan-rich antigen; n=1; Plasmodiu... 33 7.2
UniRef50_A0EE63 Cluster: Chromosome undetermined scaffold_91, wh... 33 7.2
UniRef50_A0CSW1 Cluster: Chromosome undetermined scaffold_26, wh... 33 7.2
UniRef50_A5DJ03 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_Q8DWE0 Cluster: DNA polymerase III polC-type; n=60; Lac... 33 7.2
UniRef50_UPI00015B5E53 Cluster: PREDICTED: similar to GA17752-PA... 33 9.5
UniRef50_UPI0000F1F901 Cluster: PREDICTED: hypothetical protein;... 33 9.5
UniRef50_UPI00005199E9 Cluster: PREDICTED: similar to F46F6.4; n... 33 9.5
UniRef50_UPI0000499F7A Cluster: Rho GTPase activating protein; n... 33 9.5
UniRef50_Q8CDD5 Cluster: Adult male testis cDNA, RIKEN full-leng... 33 9.5
UniRef50_Q1UAK9 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_A5VEW4 Cluster: Polysaccharide deacetylase; n=1; Sphing... 33 9.5
UniRef50_A2D7K4 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_A0C3D0 Cluster: Chromosome undetermined scaffold_147, w... 33 9.5
UniRef50_A0BVV4 Cluster: Chromosome undetermined scaffold_130, w... 33 9.5
UniRef50_A5YS53 Cluster: Helicase, C-terminal; n=1; uncultured h... 33 9.5
>UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha, mitochondrial precursor; n=29; Euteleostomi|Rep:
2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial precursor - Homo sapiens (Human)
Length = 445
Score = 235 bits (574), Expect = 1e-60
Identities = 104/184 (56%), Positives = 133/184 (72%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I RNNGYAISTPTSEQYRGDGIA+RGP G+ ++RVDG D AV+NA K AR VA
Sbjct: 261 IFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAE 320
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N+P LIEAM YR+GHHSTSDDSSAYRSV+E+ W K + P+ + + YL +G+WD E EK
Sbjct: 321 NQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEK 380
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPL 193
AW K++R V+ ++AE+K KPN + DVY EMP +L+KQ + + HL+ Y EHYPL
Sbjct: 381 AWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYPL 440
Query: 192 NQHE 181
+ +
Sbjct: 441 DHFD 444
>UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891-PA
- Drosophila pseudoobscura (Fruit fly)
Length = 439
Score = 228 bits (557), Expect = 1e-58
Identities = 102/181 (56%), Positives = 134/181 (74%), Gaps = 1/181 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGP-ALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
I+ RNNG+AISTP+ EQYRGDGIA RGP G+ T+RVDGTD AV+NA+K AR++ +
Sbjct: 254 ILFCRNNGFAISTPSHEQYRGDGIAGRGPMGYGIATIRVDGTDVFAVYNAMKEAREYVLR 313
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
NKPV+ EA+AYRVGHHSTSDDS+AYRS EEI+ W E P+ K K Y+ HKG++D E
Sbjct: 314 ENKPVVFEALAYRVGHHSTSDDSTAYRSTEEIEVWNSVEHPISKLKRYMVHKGWFDEAEE 373
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYP 196
A+ KE R V++ + +EKK KPNWKEM E VY EMP L +Q ++++EH++ + + YP
Sbjct: 374 TAYIKEVRKKVLKQIAVSEKKLKPNWKEMFEGVYAEMPEHLVEQQRELQEHIEAHKDSYP 433
Query: 195 L 193
L
Sbjct: 434 L 434
>UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 444
Score = 226 bits (553), Expect = 4e-58
Identities = 99/186 (53%), Positives = 128/186 (68%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I RNNGYAISTPT EQYRGDGIA RG + G+ +RVDG D AV+N K+AR+ V
Sbjct: 259 IFFCRNNGYAISTPTREQYRGDGIACRGRSYGMLAIRVDGNDIFAVYNVTKKAREIAVNE 318
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N+PVL+EAM YR+GHHSTSDDSS YRS++E+ W K++ P+ + + Y+E KG+WD + E+
Sbjct: 319 NRPVLVEAMTYRIGHHSTSDDSSVYRSLKEVNYWDKEDHPISRLRYYMEDKGWWDQDQEQ 378
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPL 193
W KEAR V++ +AEK KP KE+ DVY E P LQ+Q K+ +H+ KYP YP
Sbjct: 379 QWKKEARLQVMQAFADAEKALKPPVKELFLDVYKEFTPHLQEQYKECVDHVAKYPHEYPT 438
Query: 192 NQHESD 175
H D
Sbjct: 439 ELHAKD 444
>UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-PA -
Drosophila melanogaster (Fruit fly)
Length = 439
Score = 224 bits (548), Expect = 2e-57
Identities = 100/185 (54%), Positives = 133/185 (71%), Gaps = 1/185 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGP-ALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
I+ RNNG+AISTP+ EQY+GDGIA RGP G+ T+RVDGTD AV+NA+K AR++ +
Sbjct: 254 ILFCRNNGFAISTPSHEQYKGDGIAGRGPMGYGITTIRVDGTDVFAVYNAMKAAREYVLK 313
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
NKPV+ EA+AYRVGHHSTSDDS+AYR EEI+ W E P+ K K Y+ HKG++D E
Sbjct: 314 ENKPVVFEALAYRVGHHSTSDDSTAYRPAEEIEIWNSVEHPISKLKRYMVHKGWFDETVE 373
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYP 196
+ K+ R V++ + +EKK KPNW+EM E VY EMP L +Q ++E+H++ + EHYP
Sbjct: 374 NEYVKDIRKKVLKQIAVSEKKLKPNWREMFEGVYAEMPDHLIEQRSELEKHIEAHKEHYP 433
Query: 195 LNQHE 181
L E
Sbjct: 434 LKDFE 438
>UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 432
Score = 224 bits (548), Expect = 2e-57
Identities = 99/180 (55%), Positives = 131/180 (72%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I RNNGYAISTPTSEQY GDGIA +GPA GLHT+RVDG D LAV+NA K AR + N
Sbjct: 246 IFFCRNNGYAISTPTSEQYGGDGIAGKGPAYGLHTIRVDGNDLLAVYNATKEARRVALTN 305
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
+PVLIEAM YR+GHHSTSDDS+AYRS +E+Q W + P+ +FK Y+ +G+W+ E E
Sbjct: 306 -RPVLIEAMTYRLGHHSTSDDSTAYRSSDEVQTWGDKDHPITRFKKYITERGWWNEEKEM 364
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPL 193
W KE + V+ AEK+KK ++ ++ EDVY E+P RL++Q +++ H+ +Y EHYP+
Sbjct: 365 EWQKEVKKRVLTEFAAAEKRKKAHYHDLFEDVYDELPLRLRRQRDELDAHVAEYKEHYPM 424
>UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 786
Score = 188 bits (457), Expect = 2e-46
Identities = 87/175 (49%), Positives = 119/175 (68%), Gaps = 1/175 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I RNNG+AISTP +EQ+RGDGIASRGP G+ T+RVDG D LAV +AV+ A+ ++
Sbjct: 586 IFFVRNNGFAISTPAAEQFRGDGIASRGPGYGMLTIRVDGNDALAVRSAVQAAKSKALSE 645
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
+PVLIEAM YRVGHHSTSDDSSAYRS + ++ W + ++PL + + YL +G+W+ E E+
Sbjct: 646 QRPVLIEAMTYRVGHHSTSDDSSAYRSKQAVESWKQMDNPLHRMRNYLTDRGWWNDELEE 705
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYY-EMPPRLQKQMKQMEEHLKKY 211
R V+ M AEKKK+P + E Y E+P L++Q ++ E L+KY
Sbjct: 706 ETKAGHRKKVIEAMARAEKKKRPKLSSLFEGTYRGELPSNLKQQRAELAELLEKY 760
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 181 bits (441), Expect = 1e-44
Identities = 91/184 (49%), Positives = 119/184 (64%), Gaps = 5/184 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I RNNG+AISTP +QY GDGIASRGPA GL T+RVDG D LAV+ AV AR V
Sbjct: 297 IWFCRNNGFAISTPIIDQYAGDGIASRGPAYGLDTIRVDGNDALAVYAAVCEARKRAVEG 356
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
K VL+EAM YRVGHHSTSDDSS YR++EE+++W+ ++P+ + + YL K +W E EK
Sbjct: 357 KKGVLVEAMTYRVGHHSTSDDSSMYRAIEEVKEWSVVDNPIHRLRSYLVSKKWWSEEEEK 416
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY-----YEMPPRLQKQMKQMEEHLKKYP 208
A K+ + V++ AEK KP EM DV+ E+P + +Q ++ LKKY
Sbjct: 417 ALLKKNKADVLKAFSRAEKLPKPKLGEMFNDVWGVAPGEEVPAVIMEQRAELGRLLKKYG 476
Query: 207 EHYP 196
E +P
Sbjct: 477 EVWP 480
>UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid
dehydrogenase E1-alpha subunit; n=13; Magnoliophyta|Rep:
Branched-chain alpha keto-acid dehydrogenase E1-alpha
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 472
Score = 181 bits (440), Expect = 2e-44
Identities = 83/183 (45%), Positives = 118/183 (64%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + RNNG+AIST SEQ+R DGI +G A G+ ++RVDG D LAV++AV+ AR+ V
Sbjct: 289 VFICRNNGWAISTHISEQFRSDGIVVKGQAYGIRSIRVDGNDALAVYSAVRSAREMAVTE 348
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
+PVLIE M YRVGHHSTSDDS+ YR+ +EIQ W +P+ +F+ ++E G+W E E
Sbjct: 349 QRPVLIEMMTYRVGHHSTSDDSTKYRAADEIQYWKMSRNPVNRFRKWVEDNGWWSEEDES 408
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPL 193
AR +++ +Q AEK +K E+ DVY P L++Q ++E +KK P+ YP
Sbjct: 409 KLRSNARKQLLQAIQAAEKWEKQPLTELFNDVYDVKPKNLEEQELGLKELVKKQPQDYPP 468
Query: 192 NQH 184
H
Sbjct: 469 GFH 471
>UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_43, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 406
Score = 173 bits (420), Expect = 5e-42
Identities = 78/184 (42%), Positives = 119/184 (64%), Gaps = 2/184 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L RNN YAISTPT +Q+RGD IA + PA G+ TL++DG D LAV+N VK AR+ + N
Sbjct: 218 LFLCRNNHYAISTPTDDQFRGDTIAGKAPAYGMRTLKIDGNDLLAVYNGVKYAREQIIKN 277
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKG--YWDAET 379
+P IE + YR+G HSTSD S YRS EEI W +P+ + L+L+ +G ++ +
Sbjct: 278 KEPFFIEFITYRIGDHSTSDHSVLYRSQEEIDSWKSGNNPINRLGLFLKKQGLRQFNDDH 337
Query: 378 EKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
+ K+ R+ V+ ++ +++ P+ +++ DVY E+ P LQ+Q Q+ EHL KY + Y
Sbjct: 338 DNQIRKDVRNRVIAALKHGSEQQSPSIQDLFTDVYDEVLPHLQEQYTQLREHLTKYKDQY 397
Query: 198 PLNQ 187
P+N+
Sbjct: 398 PINK 401
>UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At5g34780.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 365
Score = 167 bits (407), Expect = 2e-40
Identities = 78/178 (43%), Positives = 113/178 (63%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + RNNG+AIST SEQ+R DGI +G A G+ ++RVDG D LAV++AV AR+ V
Sbjct: 59 VFICRNNGWAISTHISEQFRSDGIVVKGQAYGIRSIRVDGNDALAVYSAVCSAREMAVTE 118
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
+PVLIE M YRVGHHSTSDDS+ YR+ +EIQ W + + +F+ +E G+W E E
Sbjct: 119 QRPVLIEMMIYRVGHHSTSDDSTKYRAADEIQYWKMSRNSVNRFRKSVEDNGWWSEEDES 178
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
AR +++ +Q AEK +K E+ DVY P L+++ ++E ++K P+ Y
Sbjct: 179 KLRSNARKQLLQAIQAAEKWEKQPLTELFNDVYDVKPKNLEEEELGLKELIEKQPQDY 236
>UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=3; Piroplasmida|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Theileria parva
Length = 464
Score = 163 bits (397), Expect = 3e-39
Identities = 81/185 (43%), Positives = 115/185 (62%), Gaps = 2/185 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I RNN Y+ISTP +QY GDGIA RG ALG+ ++RVDG D A + A K R++ V +
Sbjct: 275 IFACRNNSYSISTPVRDQYIGDGIAIRGVALGIPSIRVDGNDLFASYMATKYCREYCVKH 334
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKD-ESPLQKFKLYLEHKGYWDAETE 376
+ P++IE M YR+GHHSTSD+SS YR E + W D +P+++ LYLE KG W E E
Sbjct: 335 STPIVIEYMTYRIGHHSTSDESSQYRGKGEFEAWAMDGVNPIKRLGLYLESKGLWSKEEE 394
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP-PRLQKQMKQMEEHLKKYPEHY 199
A K A +++ ++E E K L D Y+ P P L Q ++++EHL+KY + Y
Sbjct: 395 AALRKSATSYMLKKIKEYENTKAYELLPGLFDDVYDAPHPDLLAQRRELKEHLEKYKDKY 454
Query: 198 PLNQH 184
L+++
Sbjct: 455 DLSKY 459
>UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto
acid dehydrogenase E1; n=1; Toxoplasma gondii|Rep:
Mitochondrial branched-chain alpha-keto acid
dehydrogenase E1 - Toxoplasma gondii
Length = 463
Score = 161 bits (392), Expect = 1e-38
Identities = 81/188 (43%), Positives = 120/188 (63%), Gaps = 3/188 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + RNNGYAISTP +QY GDGIA RG + G+HT+RVDG D A A K+AR+ V+
Sbjct: 275 LFVCRNNGYAISTPVKDQYAGDGIAIRGISYGMHTIRVDGNDLFASLLATKKAREIIVSQ 334
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDE-SPLQKFKLYLEHKGYWDAETE 376
+PVLIE M YRVGHHSTSDDS YR E++ W + P+ + + YL++ W + +
Sbjct: 335 RQPVLIEFMTYRVGHHSTSDDSFQYRPSGELEAWGQSGIHPIARVRRYLDNLNLWSDKQD 394
Query: 375 KAWSKEARDTVVRTMQEAEK-KKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
+ K+AR T++R M+ EK K+ + +DVY + P L++Q + ++ ++K +HY
Sbjct: 395 EELRKDARATMLRMMKVVEKDKRSAVIGGIFDDVYDKEPWNLREQRESLKAFMEKNKQHY 454
Query: 198 P-LNQHES 178
P L ++ES
Sbjct: 455 PQLKEYES 462
>UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Trypanosoma|Rep:
2-oxoisovalerate dehydrogenase alpha subunit, putative -
Trypanosoma cruzi
Length = 431
Score = 159 bits (386), Expect = 6e-38
Identities = 75/178 (42%), Positives = 110/178 (61%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L RNNGYAISTP+S QY GDG+ +RG G+ RVDG D LAV V++AR+
Sbjct: 252 LFLIRNNGYAISTPSSSQYAGDGVFARGIGYGIPCARVDGNDILAVFQTVRKARELIRTT 311
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N+PVL+EA+ YR HHS+SDDS+ YRS +E++ ++ P+ +F+ YLE K W E +
Sbjct: 312 NQPVLVEALLYRSSHHSSSDDSTWYRSRDEVEVFSNLFLPVARFEKYLERKLLWTPEQSR 371
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
+ S++ R + + EK K M +DVY EM P + + K++EEH ++ + Y
Sbjct: 372 SLSQKVRQETLAELHRQEKLPKWPVSSMHDDVYKEMTPEMHQAQKELEEHYERNKKEY 429
>UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Leishmania|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit, putative - Leishmania major
Length = 479
Score = 157 bits (381), Expect = 3e-37
Identities = 73/180 (40%), Positives = 114/180 (63%), Gaps = 2/180 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ RNNGYAISTPT QY GDGI SR G+ RVDG D LAV++ V++AR+ + +
Sbjct: 297 LFFVRNNGYAISTPTHSQYMGDGILSRAVGYGIPAARVDGLDALAVYHTVRKAREMILNS 356
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
++PVL+EA+ YR+ HHSTSDDS+AYRS +EI+ + + SP+++F+ ++ +G+W E +
Sbjct: 357 HRPVLVEALTYRLSHHSTSDDSTAYRSRDEIEHFAETFSPIERFEHFVTARGWWTPEQSR 416
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNW--KEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
+ R V+ ++ E K P W + +DV+ + P L++Q Q+ EH + + Y
Sbjct: 417 EVVERTRSEVLSELRRQE--KLPAWPVSTLCDDVFEHLTPELERQRTQLVEHYQAHRSIY 474
>UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, E1
component, alpha subunit; n=32; Gammaproteobacteria|Rep:
Alpha keto acid dehydrogenase complex, E1 component,
alpha subunit - Idiomarina loihiensis
Length = 395
Score = 157 bits (380), Expect = 3e-37
Identities = 76/179 (42%), Positives = 114/179 (63%), Gaps = 1/179 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTS-EQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
I RNNGYAISTP EQY GDGIA RG G+ T+R+DG D AV A + AR V
Sbjct: 210 IFFCRNNGYAISTPAQGEQYAGDGIAPRGIGYGMKTIRIDGNDVFAVLKATQEARRLAVE 269
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
N+PVLIEAM+YR+ HSTSDD + YR+ +E W + + PL++ + ++ +G+ D +
Sbjct: 270 ENEPVLIEAMSYRMSGHSTSDDPTGYRTRDEEAGW-QAKDPLERLQKWMTDEGWLDKDHV 328
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
+ E + V+ ++E+EK P+ E++ DVY E L++Q+ +++EH++KYP+ Y
Sbjct: 329 EEHHAEVKAKVLAALKESEKVPVPHIDELINDVYDEPTDMLKEQLDELKEHIRKYPDAY 387
>UniRef50_Q4Y3F8 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=7; Plasmodium|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Plasmodium chabaudi
Length = 432
Score = 144 bits (350), Expect = 1e-33
Identities = 72/187 (38%), Positives = 114/187 (60%), Gaps = 2/187 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NN YAIST +QYRGDGIA R ALG+ ++RVDG D A + A K+ RD +
Sbjct: 246 MFICKNNLYAISTSIKDQYRGDGIAPRALALGVESIRVDGNDLFASYLATKKMRDICIQE 305
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKD-ESPLQKFKLYLEHKGYWDAETE 376
+KPV +E M+YR GHHSTSDDS+ YR EE W K+ P+ + LYL++K + +
Sbjct: 306 SKPVFMEFMSYRYGHHSTSDDSTLYRPKEENDAWKKEGVHPISRLFLYLKNKNLYTDNED 365
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPN-WKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
+ K ++ V++ +++ E K+ N + EDVY+E +++Q +Q E+ K+ +Y
Sbjct: 366 QLHRKSVKEKVLKELKKYENVKRYNIVGGLFEDVYHEEDWNIKEQREQFEQFFKENKNNY 425
Query: 198 PLNQHES 178
++ E+
Sbjct: 426 DTSKFEN 432
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 124 bits (298), Expect = 3e-27
Identities = 65/169 (38%), Positives = 96/169 (56%), Gaps = 1/169 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + RNNG+AIS P Q + IA + A G+ RVDG D LAVH A +RAR+ A
Sbjct: 215 VFVCRNNGWAISVPRERQTGSETIAQKAIAYGMRGERVDGNDLLAVHAATRRARERAEAG 274
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+E + YRV HSTSDD AYR E ++ W K P+ + + YL +G ++
Sbjct: 275 EGPTLLECVTYRVEGHSTSDDPRAYRPAELVEPW-KKRDPILRMRRYLVRRGALAEAEDE 333
Query: 372 AWSKEARDTVVRTMQEAEK-KKKPNWKEMLEDVYYEMPPRLQKQMKQME 229
+ R+ + R ++EAE KP + + EDVY E P+L++Q+ ++E
Sbjct: 334 RIRAQVREELQRVLKEAEAFAPKPPLESLFEDVYAEPLPQLREQLAELE 382
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 122 bits (294), Expect = 9e-27
Identities = 66/178 (37%), Positives = 104/178 (58%), Gaps = 5/178 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAV----HNAVKRARDF 565
I +NN YAISTP S Q++ IA R + +RVDG D LAV H A++RAR
Sbjct: 190 IFFIQNNRYAISTPNSRQFKTPTIAQRALGYDIAGVRVDGQDVLAVLAVMHEAIERAR-- 247
Query: 564 TVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYW-D 388
+ P L+E++ +R G H+TSDD YRS EE+++W + P+++ +LYL +G W D
Sbjct: 248 --SGGGPTLVESVTFRYGPHTTSDDPKRYRSQEELEEW-QARDPIERLRLYLVSQGQWSD 304
Query: 387 AETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
++ E W+ AR+ V + EAE +P+ ++ + +Y E P L +Q + ++ +L K
Sbjct: 305 SDDEALWT-AAREQVAAAVAEAEAMPRPSVDDLFDYLYAEPTPNLVRQKEYLKAYLAK 361
>UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=1; Bacillus halodurans|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
halodurans
Length = 367
Score = 118 bits (285), Expect = 1e-25
Identities = 64/174 (36%), Positives = 94/174 (54%), Gaps = 1/174 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I +NNGYAIS P +Q I R A + RVDG D AV+ VKRA +
Sbjct: 191 IFFCQNNGYAISVPFEKQSASKTIKQRSVAYDMRGERVDGNDIFAVYLTVKRAIEQARKG 250
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQK-WTKDESPLQKFKLYLEHKGYWDAETE 376
P LIEA+ R G H+T+DD+ YR EEI++ W + + PL + K Y++ KG+ E E
Sbjct: 251 RGPTLIEAVTTRFGSHTTADDAKKYRDQEEIERTWKEMQDPLTRLKAYIQAKGWLSEEEE 310
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
+ R+T+ + AE+ KP+ +M E VY P +++Q +++ E L K
Sbjct: 311 AQMKAKIRETIDEELSMAEQYPKPSISQMFEHVYENQPWYVKEQEQELAELLGK 364
>UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=2; Firmicutes|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Acholeplasma
laidlawii
Length = 345
Score = 118 bits (284), Expect = 1e-25
Identities = 69/178 (38%), Positives = 100/178 (56%), Gaps = 2/178 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NN +AISTP + + +A +G A G+ ++VDG D LA++ A K A D
Sbjct: 170 VAVIQNNQWAISTPVRKASNSETLAQKGVAFGIPYIQVDGNDMLAMYVASKEAMDRARKG 229
Query: 552 NKPVLIEAMAYRVGHHSTSDDS-SAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
+ P LIEA YR+G H+TSDD S YR+ EE +W K + + +FK YL +KGYW E +
Sbjct: 230 DGPTLIEAFTYRMGPHTTSDDPCSIYRTKEEENEWAKKDQ-IARFKTYLINKGYWSEEED 288
Query: 375 KAWSKEARDTVVRTMQEAEK-KKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPE 205
K +E + T ++ E E+ E Y EM P+L+ +Q EEH KKY E
Sbjct: 289 KKLEEEVLAEINDTFKKVESYGANVELIEIFEHTYAEMTPQLK---EQYEEH-KKYLE 342
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 118 bits (283), Expect = 2e-25
Identities = 62/171 (36%), Positives = 94/171 (54%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L +NNGYAIS P S Q + D +A R G+ + VDG D AV+ K+A +
Sbjct: 171 VFLVQNNGYAISVPKSRQMKVDYVARRAEGYGMPGVVVDGNDAFAVYLEAKKAVERARKG 230
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+EA+ YR+ H+TSDD S YRS EE + W + + P+ + + LE +G W E EK
Sbjct: 231 EGPTLLEALTYRLAPHTTSDDPSRYRSKEEEEAW-RAKDPILRLRKALEGRGLWGEEAEK 289
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHL 220
A E + R + A++ +P +E++E VY EM P ++ + + L
Sbjct: 290 ALLLELEEEFQRELALADEAPEPRPEEIVEHVYAEMGPDQRRAWEALRRGL 340
>UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=10; Bacilli|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 371
Score = 117 bits (282), Expect = 3e-25
Identities = 58/165 (35%), Positives = 96/165 (58%), Gaps = 1/165 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NNG+AISTP +Q +A + A G+ ++VDG D LAV+ K ARD++ A
Sbjct: 199 VFIIQNNGFAISTPREKQTAAKTLAQKAVAAGIPGIQVDGMDPLAVYAIAKEARDWSAAG 258
Query: 552 NKPVLIEAMAYRVGHHSTS-DDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
N PVLIE + YR G H+ S DD + YRS E +W + + PL +F+ YL KG W E
Sbjct: 259 NGPVLIETLTYRYGPHTLSGDDPTRYRSKEMDDEWVQ-KDPLTRFRKYLTDKGLWSEAKE 317
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQM 241
+ ++ ++ + + EA+K K + L++++ P +++Q+
Sbjct: 318 EEIIEKTKEEIKVAIAEADKAPKQKVSDFLKNMFEVQPQTIKEQI 362
>UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n=8;
Halobacteriaceae|Rep: Pyruvate dehydrogenase alpha
subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 419
Score = 116 bits (280), Expect = 5e-25
Identities = 60/178 (33%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAV----HNAVKRARDF 565
+ NN +AIS P +Q D +A + A G ++VDG D LAV H+A+++A+D
Sbjct: 235 VFFCNNNQWAISVPREQQTATDTLAQKAAAYGFEGVQVDGMDPLAVYQVAHDAIEKAKDP 294
Query: 564 TVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDA 385
+P LIEA+ YR G H+T+DD S YR E++ W KD+ P+ + + +L D
Sbjct: 295 DEDEMRPTLIEAVQYRFGAHTTADDPSVYREESEVEAW-KDKDPIPRLETFLVETDRLDD 353
Query: 384 ETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKY 211
++ + D V ++ AE+ +P+ M E+VY EMP RL++Q++ + +Y
Sbjct: 354 AAIESIEADIEDAVADAIEAAEETPRPDPASMFENVYAEMPQRLEQQLEYFQSIRDEY 411
>UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1,
transketolase alpha subunit; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E1, transketolase alpha subunit - Uncultured
methanogenic archaeon RC-I
Length = 359
Score = 115 bits (276), Expect = 1e-24
Identities = 58/163 (35%), Positives = 90/163 (55%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AISTP Q R + A +G A G+ + R+DG D LA + VK D
Sbjct: 186 VFICSNNQFAISTPNPLQTRAETFAQKGIAYGIPSYRLDGMDVLASYVIVKDLLDRARNG 245
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P IEA+ YR G H+TSD+ YRS E++K K+ P+ +F+ YL +KG WD + E
Sbjct: 246 EGPAFIEAICYRFGPHTTSDNPDLYRSKGEVEKIRKETDPIDRFRNYLVNKGLWDIDKET 305
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQ 244
E + + +EAE+ P ++E+ + V+ E P L+++
Sbjct: 306 RLHDEMDALIDKAAKEAEQAPAPEFEELFKHVFAEEPQFLKEE 348
>UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus cereus
Length = 371
Score = 112 bits (270), Expect = 7e-24
Identities = 57/174 (32%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + +NN YAISTP +Q +A + A G++ ++VDG D LAV+ A AR+ V
Sbjct: 199 IFVVQNNRYAISTPVEKQSAAKTVAQKAVAAGIYGIQVDGMDPLAVYAATAFARERAVNG 258
Query: 552 NKPVLIEAMAYRVGHHS-TSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
P LIE + +R G H+ DD + YR+ + +W + + P+ +F+ +LE+KG W E E
Sbjct: 259 EGPTLIETLTFRYGPHTMAGDDPTRYRTKDIENEW-EQKDPIVRFRAFLENKGLWSQEVE 317
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
+ +EA++ + + + +A++ K +++E +Y +MP L +Q + +E K
Sbjct: 318 EKVIEEAKEDIKQAIAKADQAPKQKVTDLMEIMYEKMPYNLAEQYEIYKEKESK 371
>UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=33; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus stearothermophilus
(Geobacillus stearothermophilus)
Length = 369
Score = 112 bits (269), Expect = 1e-23
Identities = 59/174 (33%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + +NN +AISTP +Q +A + A G+ ++VDG D LAV+ AVK AR+ +
Sbjct: 197 IFVVQNNRFAISTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDPLAVYAAVKAARERAING 256
Query: 552 NKPVLIEAMAYRVGHHSTS-DDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
P LIE + +R G H+ S DD + YRS E +W K + PL +F+ +LE KG W E E
Sbjct: 257 EGPTLIETLCFRYGPHTMSGDDPTRYRSKELENEWAK-KDPLVRFRKFLEAKGLWSEEEE 315
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
++A++ + +++A++ K +++ ++ E+P L++Q + +E K
Sbjct: 316 NNVIEQAKEEIKEAIKKADETPKQKVTDLISIMFEELPFNLKEQYEIYKEKESK 369
>UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Geobacillus|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Geobacillus
kaustophilus
Length = 359
Score = 109 bits (262), Expect = 7e-23
Identities = 58/167 (34%), Positives = 89/167 (53%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I +NN YAIS P +Q IA + A G+ + VDG D LAV+ +K+A +
Sbjct: 184 IFFCQNNQYAISVPYRKQTASRTIAQKALAYGMKGVLVDGNDVLAVYETMKQAVEAARRG 243
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+LIEA+ YR+G H+T+DD + YR EE++ W + + PL++ +L LE +G W E
Sbjct: 244 EGPMLIEALTYRLGPHTTADDPTKYRRPEEVETW-RAKDPLRRLRLLLERRGLWTEAQED 302
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
A + D V + A K + + + VY E P L +Q ++
Sbjct: 303 ALVAQVNDEVTAAYEAAIASKSGSIVDAFDCVYSEAPKLLAEQKDEV 349
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 105 bits (253), Expect = 8e-22
Identities = 57/167 (34%), Positives = 100/167 (59%), Gaps = 1/167 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
++ +NN Y+IS P ++ + +A + A G+ ++VDG D LAV+ A + A +
Sbjct: 187 VVFIQNNQYSISNPRNKVSKAKTLAQKCYACGIPGMQVDGNDILAVYVAAQEAFNEARKG 246
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N P LIE ++YR+ HST+D++S YRS EE +W K + P+ +F+ YL +KGY + +
Sbjct: 247 NGPTLIENVSYRLEAHSTNDNASVYRSKEEELEWRK-KDPIVRFQKYLMNKGYLTQKQVE 305
Query: 372 AWSKEARDTVVRTMQEAEKK-KKPNWKEMLEDVYYEMPPRLQKQMKQ 235
+ KEA++ VV Q+ E+ + K++ Y +M P+L++Q ++
Sbjct: 306 QFEKEAQEEVVLAHQKVEQTGNNIDIKDIFAYTYEKMTPQLEEQYEE 352
>UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=2; Thermus thermophilus|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 367
Score = 105 bits (251), Expect = 1e-21
Identities = 62/173 (35%), Positives = 89/173 (51%), Gaps = 2/173 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YAIS Q IA + A G+ VDG D LA + VK A +
Sbjct: 198 VFVCENNFYAISVDYRHQTHSPTIADKAHAFGIPGYLVDGMDVLASYYVVKEAVERARRG 257
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+E YR G HS++DD S YR EE+ W K + P+ +F+ +LE +G W+ E E+
Sbjct: 258 EGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRK-KDPIPRFRRFLEARGLWNEEWEE 316
Query: 372 AWSKEARDTVVRTMQEAEK--KKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHL 220
+E R + R ++EAE+ P W M DV+ E P L +Q ++E L
Sbjct: 317 DVREEIRAELERGLKEAEEAGPVPPEW--MFADVFAEKPWHLLRQEALLKEEL 367
>UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2;
Arthrobacter|Rep: Pyruvate dehydrogenase - Arthrobacter
sp. (strain FB24)
Length = 359
Score = 104 bits (249), Expect = 3e-21
Identities = 65/171 (38%), Positives = 90/171 (52%), Gaps = 2/171 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NNG+AIS PT Q G +A+R G+ LR+DG D +AV +A +RA A
Sbjct: 187 VFFVQNNGWAISVPTERQVAGGSVAARAAGYGIPALRIDGNDVVAVVDATRRAFAHARAG 246
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAE--T 379
+ PVLIEAM YR G HSTSDD YRS+ E ++ E PL++F+ L G D
Sbjct: 247 HGPVLIEAMTYRRGPHSTSDDPGRYRSLNE-ERDDAGEDPLERFRKTLLADGVADEAFFA 305
Query: 378 EKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEE 226
E + +A + +R +A +P EM + V+ E P LQ Q E
Sbjct: 306 EALAAAKAEEEHIRAGIQA-LGSRPG-TEMFDLVFQETTPALQAQAANWRE 354
>UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit;
n=5; Mollicutes|Rep: Pyruvate dehydrogenase EI alpha
subunit - Mycoplasma capricolum
Length = 370
Score = 102 bits (244), Expect = 1e-20
Identities = 61/176 (34%), Positives = 89/176 (50%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN +AIST SEQ + A +G A G+ ++ VDG D LA K ++
Sbjct: 189 IFVIENNKWAISTARSEQTKSINFAVKGIATGIPSIIVDGNDYLACIGVFKEVVEYVRKG 248
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N PVL+E YR+G HS+SD+ AYR E ++ K + PL + K YL K W E +
Sbjct: 249 NGPVLVECDTYRLGAHSSSDNPDAYRPKGEFEEMAKFD-PLIRLKQYLIDKKIWSDEQQA 307
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPE 205
E V EK K + ++ + Y +M L++Q K+ +E +KYPE
Sbjct: 308 QLEAEQDKFVADEFAWVEKNKNYDLIDIFKYQYDKMDIFLEEQYKEAKEFFEKYPE 363
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 101 bits (242), Expect = 2e-20
Identities = 56/176 (31%), Positives = 91/176 (51%), Gaps = 1/176 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AIS EQ +A + A G +VDG D +AV AV +A +
Sbjct: 190 VFIINNNQWAISVARGEQTHCQTLAQKAIAGGFEGWQVDGNDVIAVRYAVSKALEKARDG 249
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQ-KWTKDESPLQKFKLYLEHKGYWDAETE 376
P LIEA++YR+ H+T+DD++ Y EE + W K+ P+ + YLE +G W E E
Sbjct: 250 GGPTLIEALSYRLCDHTTADDATRYIPQEEWKVAWQKE--PIARLGYYLESQGLWSREKE 307
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYP 208
KE V + ++E P +M + +Y E+P L+KQ +++ ++ +P
Sbjct: 308 AVLQKELAQEVDQVVEEFLTMPPPKATDMFDYLYAELPVSLEKQREELADNKPSHP 363
>UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=7; Xanthomonadaceae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Xanthomonas axonopodis pv. citri
Length = 362
Score = 100 bits (240), Expect = 3e-20
Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 1/168 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I+ NNG+AIS P S Q +A +G A GLH L+VDG D +AV A+++AR +A
Sbjct: 189 ILCVINNGWAISVPRSAQTGAQTLAQKGLAGGLHCLQVDGNDLVAVLEAMRQARVRALAG 248
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEI-QKWTKDESPLQKFKLYLEHKGYWDAETE 376
+IE + YR+ H+T+DD+ YR EE+ Q W ++ PL + + YL +G WD E
Sbjct: 249 EGGTVIEFLTYRLSDHTTADDARRYRGEEEVKQGWARE--PLLRLRRYLTAQGLWDEAQE 306
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
AW + V + + M + +Y + P L Q ++
Sbjct: 307 DAWKADCSARVDEEVNAYLNTPVQPVEAMFDYLYGDPPAELLAQRAEV 354
>UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16;
Mycobacterium|Rep: Pyruvate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 356
Score = 100 bits (239), Expect = 4e-20
Identities = 52/173 (30%), Positives = 83/173 (47%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NN +AIS P Q G IA R G+ +RVDG D LA + A A
Sbjct: 183 VFFVQNNQWAISVPVQRQVAGPSIAHRAAGYGMPGVRVDGNDVLACFAVMSEAAARARAG 242
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA+ YR+G H+TSDD + YR E+ +W + P+ +++ YL+ G W E+
Sbjct: 243 GGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRW-RARDPIPRYRTYLQGAGVWSERLEE 301
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
+ ++ + E+ + VY+++ P L +Q ++ L K
Sbjct: 302 RVAARSKRLRAELRDAVVGAPDFDVSEVFDTVYHDITPDLAEQRDRLLAELAK 354
>UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,
alpha subunit; n=2; Deinococcus|Rep: 2-oxo acid
dehydrogenase, E1 component, alpha subunit - Deinococcus
radiodurans
Length = 381
Score = 99.1 bits (236), Expect = 1e-19
Identities = 56/172 (32%), Positives = 86/172 (50%), Gaps = 3/172 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AIST Q + I + A G+ VDG D +AV A ++ A
Sbjct: 205 LFVCENNQWAISTHIRHQTASENIHIKAKAYGMPGFYVDGNDVVAVMEVCHHAAEWVRAG 264
Query: 552 NKPVLIEAMAYRVGHHSTSDDSS--AYRSVEEIQKWTKDESPLQKFKLYLEHKG-YWDAE 382
N P L+E + YRVG HS +D + +YR+ +E+ +W P+Q+ + LEH G AE
Sbjct: 265 NGPALVECLTYRVGSHSNADADAEKSYRTRDEVNEWL-GRDPIQRVENLLEHLGDPISAE 323
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEE 226
E + ++ AE P+W+ M EDVY +MP L++Q + E
Sbjct: 324 ERAGMIAEIHKQIDDDVRRAEAAGYPDWRIMFEDVYSDMPDHLRQQAAMLRE 375
>UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 365
Score = 98.7 bits (235), Expect = 1e-19
Identities = 54/173 (31%), Positives = 90/173 (52%), Gaps = 2/173 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NN +AIS P + Q +A + A + L+VDG D LAV+ A K A D A
Sbjct: 186 VFICQNNHWAISLPRARQSHSKTLAQKALAYDMPGLQVDGNDVLAVYAAAKEAVDRARAG 245
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P IE++ YR+ H+T+DD YR EE+++W + P+ +F+ YL +G E+
Sbjct: 246 GGPSFIESVTYRLSMHTTADDPKKYRREEEVEQWVR-RDPIIRFEKYLLGRGLLSEESVA 304
Query: 372 AWSKEARDTVVRTMQEAEK--KKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHL 220
+ E + + + + +K + EM + Y E+PP L +Q +Q+ L
Sbjct: 305 GIADEVQAEIKEAEERWTRMTEKPADPMEMFDHAYEELPPYLLEQKEQLRREL 357
>UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n=1;
Halobacterium salinarum|Rep: Pyruvate dehydrogenase
alpha subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 322
Score = 97.9 bits (233), Expect = 2e-19
Identities = 56/174 (32%), Positives = 84/174 (48%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ NN +AIS P Q D IA++ A G ++VDG D LAV+ V A +
Sbjct: 143 VFFCENNNWAISLPRERQTASDSIAAKADAYGFEGVQVDGNDPLAVYETVTDALA-GARD 201
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+L+E++ YR G H+TSDD YR EE + P+ ++ YL +G DA +
Sbjct: 202 GTPILVESLTYRQGAHTTSDDPDRYRPEEEDLPAWRTADPVDRYADYLHDQGVIDAGFVE 261
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKY 211
A D + ++ AE P E+ + VY E PR+ Q +E L+ +
Sbjct: 262 ECFDAAADEIDDAVETAEAAGAPAVDELFDHVYAERTPRIDDQKAWLESWLETH 315
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 97.1 bits (231), Expect = 4e-19
Identities = 57/170 (33%), Positives = 86/170 (50%), Gaps = 8/170 (4%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANN---- 550
NNG+AIS P S Q D A + A G +RVDG D LA + K A D N
Sbjct: 199 NNGWAISIPESRQTASDTFAEKAGAYGFEGIRVDGMDPLASYAVTKEAADRARRNEDDSP 258
Query: 549 ----KPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAE 382
+P LIE + YR G H+T+DD +AYR + + W + PL + + +L G D +
Sbjct: 259 VDAPRPALIEFLEYRFGAHTTADDPTAYRDPDAVDPW-RALDPLDRMEAFLRETGRIDDD 317
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
A +EA + V + AE +P+ +M + Y ++PP L++Q ++
Sbjct: 318 GVAAIHEEADEIVADAIDFAE-SVEPDPADMFDHAYADLPPELRRQRDEL 366
>UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1 alpha subunit; n=23; Bacteria|Rep:
Branched-chain alpha-keto acid dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 352
Score = 95.9 bits (228), Expect = 9e-19
Identities = 56/155 (36%), Positives = 76/155 (49%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + +NN YAIS P S+Q G +A+RG G+ + VDGTD LAV+ VK A +
Sbjct: 198 IFMVQNNEYAISVPLSQQVAGGSVAARGRGYGMPGVEVDGTDVLAVYEVVKEAHERARRG 257
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA R+ HS+ DD YR EEI + P++K + YL G D E+
Sbjct: 258 EGPTLIEARCIRITSHSSDDDQRRYRDPEEIAA-VQVRDPIRKARQYLFEHGLMDEAAEQ 316
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE 268
++ V AE + +E L VY E
Sbjct: 317 ELERKVAAIVDDATDWAEAQPYAAPEEALRHVYKE 351
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 95.5 bits (227), Expect = 1e-18
Identities = 58/172 (33%), Positives = 89/172 (51%), Gaps = 1/172 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NN YAISTP EQ +A R G+ LRVDG D AV AV A +
Sbjct: 193 VFVLQNNQYAISTPLREQTNATMLADRAAGYGMPGLRVDGNDVAAVFAAVAAALERGRNG 252
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
+ P LIE + YR+ H+ SDD + YR EE++ W K P+ + + YL G D T
Sbjct: 253 DGPTLIECLTYRMESHTNSDDPTKYRDSEEVEHW-KQFDPIDRLEKYLRTTGALDDST-V 310
Query: 372 AWSKEARDTVVRTMQEA-EKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHL 220
A EA +T+ ++++A ++ + + +E+ VY L +Q + +E L
Sbjct: 311 AEVAEAAETLAASVRDAMNQEAEVDPRELFAHVYATPRTALAEQQQVLEAEL 362
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 94.7 bits (225), Expect = 2e-18
Identities = 51/170 (30%), Positives = 89/170 (52%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ NN +AIS P ++Q +A + A G+ ++DG D +AV V A +
Sbjct: 185 VIVINNNQWAISMPRAKQTAAATLAQKAIAAGIPGEQIDGNDVIAVRQRVGAAIEHARHG 244
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA++YR+G H+T+DD+S YR +++ + E P+ + + YL G WDA E+
Sbjct: 245 GGPTLIEAVSYRLGDHTTADDASRYRDEASVKEAWRCE-PIIRLRDYLARLGAWDAAQEE 303
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEH 223
A KE + V +Q P+ M + +Y +P + +Q+ ++
Sbjct: 304 ALIKECQQAVGAAVQAYLALPHPDASAMFDCLYETLPDAMAEQLDTARQY 353
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 94.7 bits (225), Expect = 2e-18
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 1/164 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ NN +AIS P S Q +A + A G+ +VDG D +AV A + A D A
Sbjct: 185 VLIVNNNQWAISVPRSRQTAAQTLAQKAIAAGIAGRQVDGNDVIAVRQAAQEALDKARAG 244
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEI-QKWTKDESPLQKFKLYLEHKGYWDAETE 376
P LIEA++YR+G H+T+DD++ YR + + Q W ++ P+ + + YL + WD E
Sbjct: 245 GGPTLIEALSYRLGDHTTADDATRYRDSDIVKQAWARE--PILRLRNYLVRQNAWDKAQE 302
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQ 244
+ + V + ++P M + +Y +P L+ Q
Sbjct: 303 EQLGRACYAQVEEAVAAYLAVEQPGPSAMFDHLYAALPRALEAQ 346
>UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Aeropyrum
pernix
Length = 377
Score = 93.5 bits (222), Expect = 5e-18
Identities = 52/176 (29%), Positives = 92/176 (52%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ +NN +AIS P + Q +A +G A G+ +R+DG D + V+ V A +
Sbjct: 196 VLVIQNNQWAISVPRARQTAAPSLAVKGLAYGVPGVRIDGNDVMVVYKIVSDAAEKARRG 255
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA+ YR+G H+T+DD S YR+ EE ++ + PL++ + ++E G +
Sbjct: 256 GGPTLIEAVTYRLGPHTTADDPSRYRTSEE-ERIMERYEPLRRMRKFMESMGILTEKEAL 314
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPE 205
+ +E V +++ K ++VY E P +Q++ + +EE LK E
Sbjct: 315 SIEEEWNSKVEEIVRKVLAKPPLPENVFFQNVYGEKPWFIQEEERDLEETLKTMEE 370
>UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase component, eukaryotic type, alpha
subunit; n=4; Vibrionaceae|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase component,
eukaryotic type, alpha subunit - Vibrio vulnificus
Length = 364
Score = 93.1 bits (221), Expect = 6e-18
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 1/164 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AIS P Q D ++ + G+ + VDG D +AV++AV A D
Sbjct: 186 VFVVNNNQWAISVPRQLQCAADLLSEKAKGAGIPGITVDGNDVVAVYDAVNNALDRARKG 245
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEI-QKWTKDESPLQKFKLYLEHKGYWDAETE 376
LIEA++YR+ H+T+DD+S YRS +E+ Q W + P+++ + YL +G W+ E E
Sbjct: 246 KGATLIEAISYRLSDHTTADDASRYRSADELKQAWQYE--PIKRLQAYLTAQGLWNEELE 303
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQ 244
+ W + V + + + + +Y +P L Q
Sbjct: 304 QQWLAHCKQQVEQAVAHYLSLPPQAPESAFDYLYASLPVELHAQ 347
>UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=4; Geobacter|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Geobacter sulfurreducens
Length = 352
Score = 92.7 bits (220), Expect = 8e-18
Identities = 48/167 (28%), Positives = 81/167 (48%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NN +AIS P + Q +A + A G ++VDG D LAV A A
Sbjct: 186 VFICQNNQWAISVPLAAQTAAPTLAQKALAYGFEGIQVDGNDVLAVFRATGEALVRARDG 245
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P IE + YR+ H+T+DD+S YR +++ W +D PL +F+ +L +G W+ +
Sbjct: 246 GGPTFIECLTYRMADHTTADDASRYRPPADVEAW-RDRDPLLRFERFLAKRGLWNGDYGA 304
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
+A + ++ E P EM E+ PR ++Q + +
Sbjct: 305 EVQAKAEGEIDEAVRRYESVPPPEPGEMFAFTCAELSPRQRRQQENI 351
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 92.3 bits (219), Expect = 1e-17
Identities = 43/172 (25%), Positives = 91/172 (52%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NN YAISTP S Q + I + A + +R+DG D A + K+A +
Sbjct: 184 VFFNQNNQYAISTPISRQMNSETIVQKSVAYEIPGIRIDGNDIFAAYFETKKALERARNG 243
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA+ +R G H+T+DD + YR+ +E + + P+ + +L+++ G+WD +
Sbjct: 244 EGPSLIEAVTWRYGAHTTADDPTKYRNQKEENEKHRQNDPITRLELFMKAYGFWDEAVVE 303
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLK 217
+E ++ + +++ E + ++ + ++ + +++Q ++ +HL+
Sbjct: 304 QLKEEVKEEIDGAVKDLETMPPADVNDIYDYMFEKPTWTIEQQKEEYIKHLR 355
>UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcus
geothermalis DSM 11300|Rep: Pyruvate dehydrogenase -
Deinococcus geothermalis (strain DSM 11300)
Length = 361
Score = 92.3 bits (219), Expect = 1e-17
Identities = 49/167 (29%), Positives = 86/167 (51%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NNG+AIS PT Q R ++ R G+ +RVDG D LA + A +
Sbjct: 190 VFILQNNGWAISVPTRTQTRATNLSLRAQGYGIPGVRVDGNDVLATYQVTLEAVNRARNG 249
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIE + YRV H+ +DD S YRS + W + P+++ + +L +G+ + +
Sbjct: 250 EGPTLIETVTYRVKPHTVADDPSRYRSDADTAGWDA-KDPVRRLQTHLLTEGHLTEKEDA 308
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
++E +Q A++ +P E+++ V+ E P+L +Q Q+
Sbjct: 309 EITREIEAEFEAALQVADRFPEPTPAEIVDHVFAEPTPQLVRQRAQL 355
>UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto
acid dehydrogenase, E1 alpha subunit; n=3;
Lactobacillales|Rep: TPP-dependent branched-chain
alpha-keto acid dehydrogenase, E1 alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 330
Score = 91.9 bits (218), Expect = 1e-17
Identities = 56/153 (36%), Positives = 76/153 (49%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN YAIS P EQY +A R A G + VDG+D V+ A K A
Sbjct: 177 IFVVENNEYAISVPIEEQYANKRMADRAKAYGFEGVTVDGSDFAEVYLAFKEAVKAARGK 236
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIE M R+ HS DD S YRS EEI++ K+++ ++ F+ L +GY E
Sbjct: 237 KGPKLIELMVSRLTSHSADDDQSVYRSKEEIEEMKKNDA-VKLFEKQLLEEGYLTDEDIA 295
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+E R + + EAE P +LE+VY
Sbjct: 296 KIDEEIRAEINQATDEAEAMPDPVPTSILEEVY 328
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 91.9 bits (218), Expect = 1e-17
Identities = 58/189 (30%), Positives = 94/189 (49%), Gaps = 3/189 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NN +AIS P++ Q R +A R G +RVDG D +AVH + A +
Sbjct: 227 VFFCQNNHWAISVPSTVQTRVP-LADRAKGYGFPGIRVDGNDVIAVHAVTEWALERAREG 285
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWD---AE 382
PVLIEA YRVG H+T+DD + YR +E +W + + PL++ + YL +G D
Sbjct: 286 KSPVLIEAFTYRVGAHTTADDPTKYRGSDEEAQW-RAKDPLERLEKYLRAEGMADDAFFA 344
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEH 202
T KA E V +T + E P+ + + Y E P + +++ EE+ + +
Sbjct: 345 TVKADGDELAAYVRKTTHDLE---TPDIRTAFANTYAEAHPLVAEELAWFEEYSAGFADE 401
Query: 201 YPLNQHESD 175
++ + D
Sbjct: 402 ASTDEADKD 410
>UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=68; Proteobacteria|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Pseudomonas putida
Length = 410
Score = 91.9 bits (218), Expect = 1e-17
Identities = 59/169 (34%), Positives = 86/169 (50%), Gaps = 7/169 (4%)
Frame = -1
Query: 717 NNGYAIST-PTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPV 541
NN +AIST A RG G+ +LRVDG D +AV+ A + A + P
Sbjct: 241 NNQWAISTFQAIAGGESTTFAGRGVGCGIASLRVDGNDFVAVYAASRWAAERARRGLGPS 300
Query: 540 LIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSK 361
LIE + YR G HSTSDD S YR ++ + + P+ + K +L G+W E +A +
Sbjct: 301 LIEWVTYRAGPHSTSDDPSKYRPADDWSHFPLGD-PIARLKQHLIKIGHWSEEEHQATTA 359
Query: 360 EARDTVVRTMQEAEKKKK------PNWKEMLEDVYYEMPPRLQKQMKQM 232
E V+ +EAE+ P+ M EDVY EMP L++Q +++
Sbjct: 360 EFEAAVIAAQKEAEQYGTLANGHIPSAASMFEDVYKEMPDHLRRQRQEL 408
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 91.1 bits (216), Expect = 3e-17
Identities = 55/168 (32%), Positives = 88/168 (52%), Gaps = 2/168 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I L NNGY TPT E+ I+ RG G+ +++VDG D ++VH AV A A
Sbjct: 167 IFLCENNGYTEWTPT-EKLTAGRISDRGVPFGIPSVQVDGNDVISVHEAVSEAVGRARAG 225
Query: 552 NKPVLIEAMAYRVGHHSTSDD--SSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAET 379
P LIEA YR H+ ++ S YR EEI++W K + P+ F L +G + E
Sbjct: 226 EGPSLIEARTYRWHGHNEGEEAFSGPYRPEEEIEEW-KGKDPITTFAARLVEQGVFAREE 284
Query: 378 EKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQ 235
+ E ++ + ++ A + P+ +E L ++Y+ PRLQ+++ +
Sbjct: 285 IERVDAEEKERIEDAVRFAVESAYPDPEEALMHLFYDERPRLQQEVNR 332
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 91.1 bits (216), Expect = 3e-17
Identities = 49/167 (29%), Positives = 85/167 (50%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NNG+AIS P +Q + IA + A + +R+DG D AV+ +A +
Sbjct: 190 VFFNQNNGFAISVPIKKQMKTKTIAQKALAYDIPGVRIDGNDIFAVYFETLKALERARNG 249
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA+ +R G H+T+DD + YR E + K P+ + + Y+E +G+WD E
Sbjct: 250 EGPTLIEAVTWRYGAHTTADDPTKYRDQSESDERRKLGDPIARLQRYMERQGWWDQEWAD 309
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
+ KE + + ++E E + + K ++ D +E P + K +
Sbjct: 310 SVQKEYTAEMDQAVEELESYPEADPK-VIFDYVFEKPTWTISEQKDL 355
>UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=37; Firmicutes|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Bacillus subtilis
Length = 330
Score = 91.1 bits (216), Expect = 3e-17
Identities = 53/153 (34%), Positives = 76/153 (49%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN YAIS P +Q + I+ R G+ + V+G D L V+ AVK AR+
Sbjct: 177 IFMCENNKYAISVPYDKQVACENISDRAIGYGMPGVTVNGNDPLEVYQAVKEARERARRG 236
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIE ++YR+ HS+ DD S+YR EE+++ K PL ++ YL+ G E E+
Sbjct: 237 EGPTLIETISYRLTPHSSDDDDSSYRGREEVEE-AKKSDPLLTYQAYLKETGLLSDEIEQ 295
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
E V EAE + L+ VY
Sbjct: 296 TMLDEIMAIVNEATDEAENAPYAAPESALDYVY 328
>UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;
n=10; Gammaproteobacteria|Rep: Dehydrogenase E1
component superfamily - Vibrio sp. Ex25
Length = 398
Score = 90.6 bits (215), Expect = 3e-17
Identities = 47/167 (28%), Positives = 86/167 (51%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AIS P S Q D ++ + G+ + VDG D +AV++A K A +
Sbjct: 220 VFVVNNNQWAISVPRSLQCAADFLSEKAQGAGIPGITVDGNDVVAVYDATKTALERARKG 279
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
LIEA++YR+ H+T+DD++ YR +++Q + E P+ + K YL ++G W E E+
Sbjct: 280 KGATLIEAVSYRLSDHTTADDATRYRKEDDVQTAWQYE-PIARLKTYLLNQGAWSDEQEQ 338
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
W + ++ V ++ + + +Y +P L Q ++
Sbjct: 339 QWLEYCKEQVELAVERYLSLPSQAPETGFDYLYESLPQELHAQRDEL 385
>UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=1; Mycoplasma penetrans|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
penetrans
Length = 359
Score = 89.0 bits (211), Expect = 1e-16
Identities = 59/173 (34%), Positives = 93/173 (53%), Gaps = 1/173 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I NN +AISTPTS++ IAS+ A GL ++VDG A +A++ AR + + N
Sbjct: 186 IFTVNNNQWAISTPTSKETGQMDIASKAIAAGLDFIKVDGNCLFASVDAIRAARAYVLEN 245
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
KP+L+E + YR G H+TSD+ YRS EE + + + P+ + + ++ G D E++K
Sbjct: 246 KKPILVEFVTYRKGPHTTSDNPRIYRS-EEYECEQEKKDPILRLERWMAQNGLLD-ESKK 303
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQM-KQMEEHLK 217
A E D V +EA K + ++DV+ L + + +Q E LK
Sbjct: 304 AQIIEKADAEV---EEAYKIMESKLSVSVDDVFDHTFKTLDESLQEQKNEALK 353
>UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=9; Mycoplasma|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Mycoplasma synoviae
Length = 374
Score = 89.0 bits (211), Expect = 1e-16
Identities = 51/175 (29%), Positives = 93/175 (53%), Gaps = 1/175 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ NN +AISTP + IA++ A + + VDG D LA ++ +K A +F
Sbjct: 199 VFCVNNNQWAISTPNHLESISSTIAAKAVAAAVPGVVVDGNDLLASYDVIKEAVEFARKE 258
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLY-LEHKGYWDAETE 376
++PVL+E + +R G H+TSD+ YR+ E +K + P+ + + Y L+ K E E
Sbjct: 259 SRPVLVEFVTWRQGPHTTSDNPRVYRTETE-EKEQEVWEPMHRIEKYLLDRKLLTKKEIE 317
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKY 211
K W+ ++ + +T +E+ K + E+ + Y E+ P L++Q ++ + K +
Sbjct: 318 KIWA-DSLEVAKKTYEESVKLNEATLDEVFDYTYAELTPELKEQKQEALDFFKAH 371
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 88.2 bits (209), Expect = 2e-16
Identities = 53/177 (29%), Positives = 85/177 (48%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L +NN +AIS P S Q + R G+ + VDG D LAV + A + +
Sbjct: 205 VFLCQNNQWAISEPVSRQSPVP-LHKRAEGAGMPGVLVDGNDVLAVLAVTRAALERARSG 263
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P +EA YR+G H+T+DD + YR E + W +++ P+ +F+ YL +G D E E
Sbjct: 264 GGPTFVEAFTYRMGAHTTADDPTRYRLSAETEAW-REKDPIDRFRTYLRAEGILDDEYEA 322
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEH 202
A + EA + R P M + Y E P++ + + +E L + +H
Sbjct: 323 ALAAEADEFAARLRAGVIALPDPQPVSMFDHAYAEPHPQV---LAERDEFLAAWEQH 376
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 87.0 bits (206), Expect = 4e-16
Identities = 51/144 (35%), Positives = 74/144 (51%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I NN Y ++TPT+ G IA+RG A G+ ++DG D AVH AV RA A
Sbjct: 183 IFFCENNQYGLTTPTTAVTAGPSIAARGDAYGVPNEQIDGNDLPAVHMAVSRAALRARAG 242
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
+ P LIEA+ YR HS + AYRS E + W K + P+ + + + G DA +
Sbjct: 243 DGPTLIEALTYRWDDHSMRANLPAYRSEAEEEAW-KSQDPIVRLEADMSKLGELDAASYA 301
Query: 372 AWSKEARDTVVRTMQEAEKKKKPN 301
A + EA V ++ A + +P+
Sbjct: 302 ALNDEAEADVEAAIEWARSQAEPD 325
>UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit; n=2; Thermoplasma|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit - Thermoplasma volcanium
Length = 337
Score = 85.8 bits (203), Expect = 1e-15
Identities = 52/155 (33%), Positives = 82/155 (52%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L NNG+AIS P Q + + I + A G+ + VDG D + +NAVK A ++ +
Sbjct: 172 VFLCENNGWAISFPVERQTKAE-IYKKAEAYGMKGVYVDGNDFIKTYNAVKEAVEYARSG 230
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N P+L+EA +YR+G HSTSDD S YR E+++ +++ PL + + KG
Sbjct: 231 N-PILVEARSYRMGPHSTSDDPSKYRQ-NEVKEGDEND-PLVIAEKAVISKGILSQSEVN 287
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE 268
E+R + +E K P+ + +DVY E
Sbjct: 288 RIKDESRKMIDEKFEERLKIPAPDPSTLFDDVYSE 322
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 85.8 bits (203), Expect = 1e-15
Identities = 50/153 (32%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN YA+ T S + RG + G+ +VDG D AV A A + +
Sbjct: 196 IYIVENNRYAMGTSVSRASAQTDFSQRGASFGIPGYQVDGMDVRAVKAAADEAVEHCRSG 255
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE- 376
P+++E + YR HS SD + YRS +E+QK + P+++ K L KG W E E
Sbjct: 256 KGPIILEMLTYRYRGHSMSDPAK-YRSKDEVQKMRSEHDPIEQVKARLTDKG-WATEDEL 313
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDV 277
K KE RD V + A+ +P+ E+ D+
Sbjct: 314 KQIDKEVRDIVADSADFAQSDPEPDVSELYTDI 346
>UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2;
Roseiflexus|Rep: Pyruvate dehydrogenase - Roseiflexus
sp. RS-1
Length = 334
Score = 84.6 bits (200), Expect = 2e-15
Identities = 44/153 (28%), Positives = 75/153 (49%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YAIS P +++ +A++ G+H + VDG D AV+ A +A + +
Sbjct: 182 VFVCENNQYAISVPVNKEVPAPTVAAKAAGYGMHGVVVDGNDVFAVYEAAHQAMERARSG 241
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+E YR H+++DD YR EE++ W + P+++F+ YL G + +
Sbjct: 242 GGPTLLECKTYRFRPHTSADDDRRYRKPEEVEAW-RARDPIKRFEHYLVEHGIITHDEIE 300
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A +E R V A P + + + VY
Sbjct: 301 AMRREVRAEVDAATDAALAAPWPPVESIADHVY 333
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 83.8 bits (198), Expect = 4e-15
Identities = 53/169 (31%), Positives = 82/169 (48%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NNGY + T + +RG + + VDG D LAV AV+ A+++ A P++
Sbjct: 220 NNGYGMGTAAARSSASTDYYTRGDYVP--GIWVDGMDVLAVRQAVRWAKEWCNAGKGPLM 277
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKE 358
IE YR HS SD ++YR+ EE+Q+ K P+ FK + G + K K+
Sbjct: 278 IEMATYRYSGHSMSDPGTSYRTREEVQEVRKTRDPITGFKDKIVTAGLVTEDEIKEIDKQ 337
Query: 357 ARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKY 211
R + +++A K+ + ML D+YY P Q +E L+KY
Sbjct: 338 VRKEIDAAVKQAHTDKESPVELMLTDIYYNTP--AQYVRCTTDEVLQKY 384
>UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. (strain CcI3)
Length = 388
Score = 83.0 bits (196), Expect = 7e-15
Identities = 46/167 (27%), Positives = 82/167 (49%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L +NNGYAIS P ++Q +A + G+ VDG D AVH ++ A + +
Sbjct: 208 VFLVQNNGYAISVPLAQQSAAPTLAHKAVGHGIIGRLVDGNDAPAVHGVLRAAVEHARSG 267
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
PVL+EA+ YR+ H+ +DD++ YR+ EE+ W + PL + L G D
Sbjct: 268 RGPVLVEAVTYRLEAHTNADDATRYRTSEEVAAW-QARDPLTLLERQLRKAGLLDDAGVA 326
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQM 232
A ++ A + + ++ + + VY + +L++Q ++
Sbjct: 327 AVARAAEELAAEMRAQFDRVPDLDPGSLFTHVYAQPTSQLREQAAEL 373
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 83.0 bits (196), Expect = 7e-15
Identities = 57/185 (30%), Positives = 84/185 (45%), Gaps = 1/185 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I +NN +AIS P Q IA R G+ +RVDG D LAV A + A +
Sbjct: 208 IFFCQNNHWAISEPVRLQSH-IRIADRAAGFGIPGIRVDGNDVLAVMAATREALERARHG 266
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P IEA+ YR+G H+T+DD + YR E++ W + P+ + + LE KG E E
Sbjct: 267 GGPTFIEAVTYRMGPHTTADDPTRYRDANELEDWAA-KDPIARVRGLLERKGLLTDELEG 325
Query: 372 AWSKEARDTVVRTMQE-AEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYP 196
+ +A D V R M+ P ++ + VY L +Q +L + +
Sbjct: 326 RVAAKA-DAVARDMRAGCINMPDPQPLDIFKHVYSTPNSWLDRQEDHYSRYLASFGDPAA 384
Query: 195 LNQHE 181
N E
Sbjct: 385 ANSEE 389
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 82.6 bits (195), Expect = 9e-15
Identities = 51/167 (30%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +NN YAIS P S + RG G+ +R+DG D +A + V+ D +
Sbjct: 199 VFMLQNNQYAISVPASVPSAACPLYKRGYGFGIPGIRIDGNDVIAAYAVVREYMDRARSG 258
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA YR+G H+TSDD + YRS +E ++W + P+ + + YL G EK
Sbjct: 259 KGPHLIEAFTYRLGAHTTSDDPTRYRSEDEHREWLALD-PIIRLERYLFSLG-----VEK 312
Query: 372 AWSKEARD----TVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQ 244
W R +V+ +P+ K++ ++VY P + Q
Sbjct: 313 TWFDRIRADIQLSVIGFRNAVLSIPQPDTKKIFDNVYSAYHPLVSSQ 359
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 82.6 bits (195), Expect = 9e-15
Identities = 52/160 (32%), Positives = 83/160 (51%), Gaps = 7/160 (4%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN +AIS PT+ Q + R G+ ++VDG D +A+ ++ A ++ + PV
Sbjct: 215 NNQWAISEPTTVQ-SPTSLFRRATGFGIPAVQVDGNDVIAMMAVLRSALEYARSGKGPVF 273
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKG----YW-D--AET 379
+EA YR+G H+T+DD + YR+ EE W K + P+ + + YL+++G W D AE
Sbjct: 274 VEAWTYRMGAHTTTDDPTRYRTAEEESTWGKTD-PIVRLRTYLQNRGIINQVWLDGLAER 332
Query: 378 EKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPP 259
E A+ E R V + P +++ DVY E P
Sbjct: 333 EDAFGAEVRAAV-------HENATPVMADLMADVYAEPTP 365
>UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=5; Mycoplasma|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
genitalium
Length = 358
Score = 81.8 bits (193), Expect = 2e-14
Identities = 46/172 (26%), Positives = 88/172 (51%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ NN +AIST T + ++ + A G+ +RVDG D +A + A++ A ++
Sbjct: 187 VFCINNNQFAISTRTKLESAVSDLSVKAIACGIPRVRVDGNDLIASYEAMQDAANYARGG 246
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N PVLIE +YR G H+TSDD S YR+ +E ++ K + P+++ + +L + + E+
Sbjct: 247 NGPVLIEFFSYRQGPHTTSDDPSIYRTKQEEEEGMKSD-PVKRLRNFLFDRSILNQAQEE 305
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLK 217
+ + ++ + E+ + Y E+ P L +Q + +++ K
Sbjct: 306 EMFSKIEQEIQAAYEKMVLDTPVSVDEVFDYNYQELTPELVEQKQIAKKYFK 357
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 80.6 bits (190), Expect = 4e-14
Identities = 52/166 (31%), Positives = 78/166 (46%), Gaps = 2/166 (1%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN Y + T RG + LR++G D LAV A+K +D+ + N P+L
Sbjct: 236 NNKYGMGTSVERASAMTEYYKRG--YYIPGLRINGMDVLAVIAAMKYGKDYVLGGNGPLL 293
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKE 358
E YR HS SD +AYRS +E+Q + P+ ++ + G + K KE
Sbjct: 294 YEFQTYRYAGHSVSDPGTAYRSRDEVQA-ERANDPITTYREKMIEWGVLSEDDVKTMDKE 352
Query: 357 ARDTVVRTMQEAEKKKKP--NWKEMLEDVYYEMPPRLQKQMKQMEE 226
R V R QEAEK +P N + ED+Y Q++ + ++E
Sbjct: 353 IRSKVDREAQEAEKMAEPPLNSDVLFEDIYVRGSEPAQRRGRTVDE 398
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 80.2 bits (189), Expect = 5e-14
Identities = 49/153 (32%), Positives = 72/153 (47%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN Y I T S I R + ++RVDG D +AVH AVK ++ +
Sbjct: 174 LFICENNFYGIGTAVSRASALSDIHKRTCGYDIPSVRVDGMDVMAVHEAVKWGAEWVREH 233
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
++P LIEAM YR HS +D YRS E++ W K P+ F+ L +G
Sbjct: 234 SRPYLIEAMTYRFRGHSMADPGK-YRSAAEVELW-KSRDPIPNFEKRLVEEGIATEAELA 291
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A ++ R V + AE+ P E+ D+Y
Sbjct: 292 AVLEKCRGVVADAVAFAEESPWPEDDEVYSDIY 324
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 79.4 bits (187), Expect = 8e-14
Identities = 48/127 (37%), Positives = 65/127 (51%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NN +AISTP+ Q +A R G LRVDG D LAVH A D +
Sbjct: 247 VFFCQNNQWAISTPSRRQ-SPVRLARRADGFGFPGLRVDGNDVLAVHAVTTWALDRARSG 305
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
PVLIEA YR+ H+TSDD++ Y+ +EI W + P+++ + L AE E
Sbjct: 306 RGPVLIEANTYRMAPHTTSDDATRYQPPDEITAW-QARDPIERLRRLLA------AEVEA 358
Query: 372 AWSKEAR 352
W E R
Sbjct: 359 GWFDEVR 365
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 78.6 bits (185), Expect = 1e-13
Identities = 49/134 (36%), Positives = 70/134 (52%), Gaps = 2/134 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NN +AISTP++ Q +A R G +RVDG D LAVH A + +
Sbjct: 193 VFFCQNNQWAISTPSARQSPVP-LARRAAGFGFPGVRVDGNDVLAVHAVTTWALEHARSG 251
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYL--EHKGYWDAET 379
PVLIEA YR+ H+TSDD+S Y+ E+ W + P+ + L L H W E
Sbjct: 252 QGPVLIEANTYRMAPHTTSDDASRYQEAAEVAAW-RARDPIDRVALLLGHTHDPAW-FEG 309
Query: 378 EKAWSKEARDTVVR 337
+A ++EA T+ R
Sbjct: 310 VRAEAEEAAATLRR 323
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 77.4 bits (182), Expect = 3e-13
Identities = 48/153 (31%), Positives = 72/153 (47%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ +NN +AIS PT +Q R + R G +RVDG D LA K A +
Sbjct: 220 VFFCQNNQWAISEPTEKQTRVP-LYQRAQGYGFPGVRVDGNDVLACLAVTKWALERARRG 278
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+EA YR+G H+TSDD + YR+ EE + W + + P+ + + YLE + D
Sbjct: 279 EGPTLVEAFTYRMGAHTTSDDPTKYRADEEREAW-EAKDPILRLRTYLEASNHADEGFFA 337
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
E+ R + P+ + E+VY
Sbjct: 338 ELEVESEALGRRVREVVRAMPDPDHFAIFENVY 370
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 77.4 bits (182), Expect = 3e-13
Identities = 45/153 (29%), Positives = 77/153 (50%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I NN Y +ST + IA+R + G+ + +DG + + V+ V++A +
Sbjct: 170 IFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQKAAEKCRRG 229
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
PVLIE+ YR HS S D++ YR+ EEI+ W K + P++ K YL + +
Sbjct: 230 EGPVLIESRTYRWLGHSKS-DANVYRTKEEIESW-KAKDPIEFLKNYLIENNLSNEDELD 287
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+ A+ ++ ++ A+ P + +LEDVY
Sbjct: 288 KIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVY 320
>UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=3; Pyrobaculum|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Pyrobaculum aerophilum
Length = 372
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/162 (30%), Positives = 86/162 (53%), Gaps = 2/162 (1%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN YAIS P S Q ++++ A GL + DG D LAV A + +P L
Sbjct: 212 NNQYAISVPVSIQTAVSRLSTKAAAYGLVGVSADGMDLLAVVKTAMWAVE-KARRGEPTL 270
Query: 537 IEAMAYRVGHHSTSDDS-SAYRSVEEIQKWTKDESPLQKFKLYLEHKG-YWDAETEKAWS 364
+E + YR G H+T+DD + YR +E++++ + + PL + + +L +G Y + + + W
Sbjct: 271 VEYVMYRFGPHTTADDPLTKYRDPKEVEEYRRWD-PLARLEKFLIRQGIYSEGDVKTIW- 328
Query: 363 KEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMK 238
+EA V +EAE +E++ DVY +P L++ ++
Sbjct: 329 EEAEREVKEAAKEAEALPDVPAEELINDVYSFVPKSLREWLE 370
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 76.6 bits (180), Expect = 6e-13
Identities = 49/152 (32%), Positives = 69/152 (45%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NNGYA+ T ++ RG G+ L VDG D L V A A D+ A
Sbjct: 200 IFVIENNGYAMGTSIQRANAHTALSERGAGFGIPALVVDGMDVLEVRGAATVAVDWVQAG 259
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+++E YR HS S D + YRS EE+ ++ PL K L G +AE K
Sbjct: 260 KGPIILEMKTYRYRGHSMS-DPARYRSREEVNDMKENHDPLDNLKKDLFAAGVPEAELVK 318
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDV 277
++ R V AEK P +E+ ++
Sbjct: 319 L-DEDIRQQVKEAADFAEKAPLPADEELYTNI 349
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 75.8 bits (178), Expect = 1e-12
Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN Y + T S RG + L+V+G D LAV+ A K A+D+ ++ P++
Sbjct: 244 NNKYGMGTAASRSSAMTEYFKRGQYIP--GLKVNGMDILAVYQASKFAKDWCLSGKGPLV 301
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKE 358
+E YR G HS SD + YR+ +EIQ P+ K++L G KA+ K
Sbjct: 302 LEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDKS 361
Query: 357 ARDTVVRTMQEAEKKKKPNWK--EMLEDVY 274
AR V ++ A+ P K + EDVY
Sbjct: 362 ARKYVDEQVELADAAPPPEAKLSILFEDVY 391
>UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=11; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase beta subunit - Bacteroides
thetaiotaomicron
Length = 678
Score = 74.1 bits (174), Expect = 3e-12
Identities = 49/177 (27%), Positives = 86/177 (48%), Gaps = 3/177 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPAL-GLHTLRVDGTDTLAVHNAVKRARDFTVA 556
I + ++NGY IS P SEQ +A L + +G D NA+ AR++ ++
Sbjct: 177 IFVIQDNGYGISVPKSEQTANRKVAENFSGFKNLKIIYCNGKDVFDSMNAMTEAREYAIS 236
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKF-KLYLEHKGYWDAET 379
PV+++A R+G HS SD + YR E++ + K+ PL KF ++ L +K + E
Sbjct: 237 TRNPVIVQANCVRIGSHSNSDKHTLYRDENELE-YVKEADPLMKFRRMLLRYKRLTEEEL 295
Query: 378 EKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE-MPPRLQKQMKQMEEHLKKY 211
+ E++ + ++A +P+ K + + V E P+ K+ EE K +
Sbjct: 296 LQI-EAESKKELSAANRKALAAPEPDPKSIYDFVMPEPYQPQKYKEGTHQEEGEKTF 351
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 74.1 bits (174), Expect = 3e-12
Identities = 48/153 (31%), Positives = 79/153 (51%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L NN YA+S P + R + ++ R A + + VDG D LAV+ AV++A +
Sbjct: 187 VYLCENNQYAMSMPIQKACRLNHLSQRAAAYAIAGITVDGNDALAVYEAVRQAVARARSG 246
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+EA+ YR HS S D AYRS +E++ W + P+ + ++ DAE K
Sbjct: 247 YGPTLVEAITYRWKGHSKS-DRQAYRSRDEVKDW-QSRDPIMRLARLIQMS---DAEF-K 300
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A +AR + ++ A+ +P+ + E +Y
Sbjct: 301 AIVDQARTMIEEAVEFAQASPEPDPDTIFEGLY 333
>UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component,
alphasubunit; n=1; Mycoplasma agalactiae|Rep: Pyruvate
dehydrogenase E1 component, alphasubunit - Mycoplasma
agalactiae
Length = 363
Score = 72.9 bits (171), Expect = 7e-12
Identities = 45/174 (25%), Positives = 82/174 (47%), Gaps = 1/174 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AIS P Y ++ R + + +RVDG D +AV+ ++ +
Sbjct: 191 VTVVMNNQWAISVPEHNSYIVKTLSQRAKSYDMPGVRVDGNDLIAVNEVMEEVYYYVREG 250
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
N PVL+E + +R G H+TSD+ YRS E++ + P + + YL + E K
Sbjct: 251 NGPVLVEMVTWRQGQHTTSDNPRVYRS-RELEMEKEKWEPFHRIEAYLLSEKLITEEDIK 309
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE-MPPRLQKQMKQMEEHLKK 214
WS+ A + +++ + + + D YE +P L +Q + + +K
Sbjct: 310 VWSEAAAEEAKAAYALSKELCEGTTFDHIYDYTYEKLPADLVRQKETNRKLFEK 363
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 72.9 bits (171), Expect = 7e-12
Identities = 46/150 (30%), Positives = 73/150 (48%), Gaps = 2/150 (1%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN YAI++ +++ GD I G+ ++DG D L V ++A + P L
Sbjct: 171 NNFYAINSRQAQRQSGDNIYKMAQVYGIPGYQIDGNDVLKVSEYAEKAIERCRKGEGPTL 230
Query: 537 IEAMAYR-VGHHSTSDD-SSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWS 364
+E ++YR GH T DD YRS EE W + P++ +K YL + D + EK+ +
Sbjct: 231 LECVSYRWKGHIGTVDDLGVGYRSQEEYDYWI-SKCPIKWYKDYLRVRNILDDKLEKSIN 289
Query: 363 KEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+E V + A KP +E+ + VY
Sbjct: 290 EEIDKLVKDAFEFAVNSPKPQPEELFDFVY 319
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 72.5 bits (170), Expect = 1e-11
Identities = 48/157 (30%), Positives = 81/157 (51%), Gaps = 2/157 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRV-DGTDTLAVHNAVKRARDFTVA 556
I NN Y IST S + + R A G+ V DG D +AV+ ++ ++ A
Sbjct: 184 IFFITNNRYGISTDISYSTKIPHLYQRAAAYGIPGHYVEDGNDVIAVYEKMQEVIEYVRA 243
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYL-EHKGYWDAET 379
P ++E +YR HST+ D+ YR+ EE+ +W K + PL+K++ YL E+K D E
Sbjct: 244 GKGPAMVEVESYRWFGHSTA-DAGVYRTKEEVNEW-KAKDPLKKYRKYLTENKIATDEEL 301
Query: 378 EKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE 268
+ A + + V +++ A++ P+ EDV+ +
Sbjct: 302 D-AIEAQVAEQVEASVKFAQESPDPDISVAYEDVFVD 337
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 72.5 bits (170), Expect = 1e-11
Identities = 38/118 (32%), Positives = 61/118 (51%)
Frame = -1
Query: 627 LRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWT 448
L+VDG D LAV + A+++ ++ P+++E +YR HS SD S YR +IQ
Sbjct: 243 LQVDGMDVLAVQEGTRWAKEWCLSGKGPIVLEFDSYRYVGHSMSDPDSQYRKKSDIQDVR 302
Query: 447 KDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
K + K K ++ +G E K K+ + V + +Q AEK+K E+ D+Y
Sbjct: 303 KTRDCIHKMKDFMLEEGIMTDEEMKKLEKDVKKEVDQQLQPAEKQKPTPRSELFTDIY 360
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 70.5 bits (165), Expect = 4e-11
Identities = 47/174 (27%), Positives = 76/174 (43%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AI + R + G+ + VDG D LAV A +RA D
Sbjct: 428 VFVVENNNWAIGMAAQRSTATPAVWQRADSFGVAGVEVDGMDVLAVRGAARRAIDRARRG 487
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA+ YR HS +D R+V++ + W P++ F+ L+ GY ET
Sbjct: 488 EGPTLIEALTYRFRGHSVADPDE-MRAVKQKEAWVV-RDPIKSFEEELKRLGYASDETIA 545
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKY 211
A + + V ++ AE +P+ +E + ++ K E L +Y
Sbjct: 546 ATRAKVKAVVDDAVKFAETSPEPDVQECGQFIFAPPYTEAGKPEPLTNEQLHQY 599
>UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Thermoplasmatales|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Picrophilus
torridus
Length = 333
Score = 70.5 bits (165), Expect = 4e-11
Identities = 42/168 (25%), Positives = 84/168 (50%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +AIS P EQ + + I+ + A G +++DG + + ++A++ A N
Sbjct: 169 LFICENNQWAISYPVEEQTKVE-ISKKAEAYGFTGIKIDGNNFIEAYHAIRNAIKDVEKN 227
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+LI+A+ YR+G H+T+DD + YR + I PL + ++ + E
Sbjct: 228 KMPLLIDAVTYRMGPHTTADDPNKYR--KTIINEGDPLDPLSIIEDDIKKMKILNDEEIS 285
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQME 229
E + V + ++ EK KP + + +++Y P + ++ ++E
Sbjct: 286 NIKNEINNMVSKEVERYEKMNKPGKETLFKNIYENEPWYITEERGEIE 333
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 70.1 bits (164), Expect = 5e-11
Identities = 45/149 (30%), Positives = 67/149 (44%), Gaps = 1/149 (0%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NNGY+ T T E G I +R A G+ +VDG D LAV+ ++ P
Sbjct: 186 NNGYSEYTRTDEIAAGS-ITARAEAFGIEAHKVDGQDVLAVNELTQKLVARCRKGEGPFF 244
Query: 537 IEAMAYRV-GHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSK 361
+E YR GHH + YRS +E + W ++ P+ +F+ YL +G E +A +
Sbjct: 245 VELETYRYHGHHVGDINREYYRSKDEEKDWRENRDPIIRFRAYLVDQGIASEEEIEAMNA 304
Query: 360 EARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
E + AE P+ E+ VY
Sbjct: 305 EIEKDATDAVAYAEAAPYPDASEVDMHVY 333
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 69.7 bits (163), Expect = 7e-11
Identities = 32/118 (27%), Positives = 62/118 (52%)
Frame = -1
Query: 627 LRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWT 448
++VDG D LAV + ARD+ ++ P+++E YR HS SD + YR+ +IQ
Sbjct: 243 IKVDGMDVLAVQEGTRYARDYCMSGKGPIVMELDCYRYMGHSMSDPDNQYRTKSDIQHVK 302
Query: 447 KDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
++ ++K + ++ +G + K+ + V + +Q+A+K+ E+ D+Y
Sbjct: 303 QERDCIRKMREFMATEGIMTEDEMSKMEKDVKKEVDQDLQKAQKQPMTKLDELFTDIY 360
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 69.7 bits (163), Expect = 7e-11
Identities = 48/154 (31%), Positives = 75/154 (48%), Gaps = 1/154 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I++ NN Y + T T + RG + L+VDG D LAV A K A++ + N
Sbjct: 223 ILVCENNHYGMGTATWRSAKSPAYFKRGDYVP--GLKVDGMDALAVKQACKFAKEHALKN 280
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKF-KLYLEHKGYWDAETE 376
P+++E YR HS SD S YR+ +EI + P+++ KL L H + E
Sbjct: 281 G-PIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQVRDPIERVRKLLLTHDIATEKEL- 338
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
K KE R V + +A++ P+ E+ ++Y
Sbjct: 339 KDMEKEIRKEVDDAVAQAKESPIPDASELFTNMY 372
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 68.9 bits (161), Expect = 1e-10
Identities = 46/120 (38%), Positives = 59/120 (49%), Gaps = 3/120 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I NN YA+ST + R IASR P LG + DG D L+VH A++ A
Sbjct: 212 IFYVENNLYAVSTHIQDATRETRIASRCPMLGFTGIECDGMDILSVHQAMREACRIIEEE 271
Query: 552 NKPVLIEAMAYRVGHHSTSDDSS--AYRSVEEIQKWTKDESPLQKFKLYLEHKGY-WDAE 382
PV+IEA YR H S S S YR+ EE ++W K P+ + L+ G DAE
Sbjct: 272 GGPVVIEAQCYRYLHQSGSKSGSDFGYRTREEEEEW-KSRDPIALAERRLKELGIAGDAE 330
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 68.9 bits (161), Expect = 1e-10
Identities = 48/158 (30%), Positives = 67/158 (42%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NNGYA+STP S +A R A G+ ++ VDG D AV AV A
Sbjct: 169 IFVCENNGYAVSTPASATVPVKDVAERARAYGMPSIIVDGQDVDAVEAAVAEAVGRARTG 228
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+E YR H+ + E+ +W K PL ++ L G A +
Sbjct: 229 GGPTLVETKTYRYADHAVNMGRVLLDRGGEVDEWRK-RDPLALYRAKLIAGGTAAALLD- 286
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPP 259
A +E D V +Q A P E +DV+ + P
Sbjct: 287 AIEREVADEVADALQFARDSAWPEQAEAFDDVFVDRLP 324
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 68.5 bits (160), Expect = 2e-10
Identities = 46/153 (30%), Positives = 73/153 (47%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YA STP Q +A RGPA + VDG D LAV+ A +RA
Sbjct: 187 VFICNNNQYAYSTPLHLQMACANVADRGPAYNMPAEIVDGNDVLAVYEATQRAVTHARGG 246
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+E +R+ HS + D++ Y ++W K + ++ K LE + E ++
Sbjct: 247 LGPYLLECKTFRMTGHS-AHDAATYVPKGLFEEWGKLDPIVRLEKRMLEERWSLQEEIDE 305
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+ R+ V + AE+ P+ +L+DVY
Sbjct: 306 LHAAVIRE-VDDAVAWAEQSPYPDAASLLDDVY 337
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 68.1 bits (159), Expect = 2e-10
Identities = 48/153 (31%), Positives = 67/153 (43%), Gaps = 1/153 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I L NN +A+S E IA R A G+ VDG D +AV+ AV RA +
Sbjct: 173 IWLCENNQWAVSVSVREATAVKQIADRAGAYGMPGEVVDGQDVVAVYEAVSRAVERARRG 232
Query: 552 NKPVLIEAMAYRV-GHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
P LIEAM YR GH+ D YR EE+++W K+ P+ L +G +
Sbjct: 233 EGPSLIEAMTYRFRGHY--EGDPDTYRDREEVERWRKERDPILLLANRLRSEGLASEQDL 290
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDV 277
+ + V +EA P + + E V
Sbjct: 291 EQIRARVQREVDEAAEEALGAPMPERERIFEFV 323
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 68.1 bits (159), Expect = 2e-10
Identities = 39/151 (25%), Positives = 70/151 (46%)
Frame = -1
Query: 726 LXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNK 547
+ NN Y + T +A++ + + +VDG D AV +R + +
Sbjct: 194 IVENNQYGMGTSVERATAMTDLAAKFNSYAIGNEKVDGMDLEAVIECGERVAERVRETGR 253
Query: 546 PVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAW 367
P +EA+ YR+ H +D YR+ EE++KW + P+ + L + D E +
Sbjct: 254 PYAVEAITYRIAPHGAADFFEKYRTKEEVEKW-RARDPIGILEKKLLERDALDEERIEEI 312
Query: 366 SKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
EAR V ++ A++ ++P +E+ DVY
Sbjct: 313 KDEARQRVSEAVKYADESEEPPIEELYTDVY 343
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 68.1 bits (159), Expect = 2e-10
Identities = 48/153 (31%), Positives = 71/153 (46%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YA + E + +A R A G+ + VDG D V+ A +RAR VA
Sbjct: 169 LFVCENNLYAGAQRYEEHTKIRDMADRAVAYGIPGIVVDGNDARVVYAAAERARARAVAG 228
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIE YR H S D Y+ EEI W K+ PL + + + + D + K
Sbjct: 229 EGPSLIECKTYRCRGHGES-DHQLYQPPEEIASW-KERCPLPRLRDEVLAQELLDEKALK 286
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+ E V ++ AE+ P+ ++ L DVY
Sbjct: 287 SMEDEISRIVEDAVRFAEESPWPDPEDALSDVY 319
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 67.7 bits (158), Expect = 3e-10
Identities = 47/155 (30%), Positives = 69/155 (44%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NNGY +ST T+ IA R A + + V+G V A RA + A
Sbjct: 187 IFVCENNGYGMSTSTARSTAVKNIADRAAAYSMPGVIVNGNIFSEVAEASYRAVERARAG 246
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIE+ YR HS S D + YR+ EEI+ W + P+ F+ L G+ D + +
Sbjct: 247 EGPTLIESKTYRHRGHSKS-DRNRYRTKEEIEDWMSNRDPITLFENELREFGFIDDKGIE 305
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE 268
A + ++ A+ P+ E VY E
Sbjct: 306 AIRSAVSQEIADGIEFAKASPSPDVSETGNYVYTE 340
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 67.7 bits (158), Expect = 3e-10
Identities = 47/153 (30%), Positives = 68/153 (44%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN +A STP IA R A + +RV+G D AV+ K A +
Sbjct: 204 IFVNENNLFAESTPQWYSSASGTIAERAAAYNMPGVRVNGKDLFAVYQVAKEAVERARRG 263
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P LIEA+ YR H D Y+++E +K D L F+ Y G E
Sbjct: 264 EGPTLIEAVTYR-DHGHFEGDEQKYKALEGEEKDWADVDALDVFRDYAIEHGLLTEEELD 322
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A +E+R V ++ A+ P + +LEDV+
Sbjct: 323 AILEESRKDVEEAIKFAQDSPIPRSESLLEDVF 355
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 66.9 bits (156), Expect = 5e-10
Identities = 45/157 (28%), Positives = 63/157 (40%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN Y + T RG + LRVDG D L V A + A D +
Sbjct: 198 IFICENNRYGMGTSVERAAASTDYYKRGDYIP--GLRVDGMDVLCVREATQFAADHCRSG 255
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+L+E YR HS SD +YR+ EEIQ+ P+ K + + E K
Sbjct: 256 KGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPITLLKDRMLNNNLSSVEELK 315
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP 262
E R + Q A +P +E+ +Y P
Sbjct: 316 EIDVEVRKEIEEAAQFATTDPEPPLEEIANHIYNNEP 352
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 66.9 bits (156), Expect = 5e-10
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 3/151 (1%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NNGY +STPT EQYR +A RG G+ + +DG + L V+ + + +PVL
Sbjct: 204 NNGYGLSTPTVEQYRCKDLADRGAGYGMESHIIDGNNILEVYTKISEIAESIRKEPRPVL 263
Query: 537 IEAMAYRV-GHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSK 361
+E +R+ GH S + Y E + +W + + P+ F+ YL K + ++ +
Sbjct: 264 VEFKTFRMRGHEEAS--GTKYVPQELMDEW-QQKDPVLNFEEYLIAKNILTNDLKEKFRT 320
Query: 360 EARDTVVRTMQEA--EKKKKPNWKEMLEDVY 274
E + + +Q A E + + L+DVY
Sbjct: 321 EILAEIDKNLQLAFSEDIIVSDATKELDDVY 351
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 66.1 bits (154), Expect = 8e-10
Identities = 45/158 (28%), Positives = 64/158 (40%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN Y + T RG + LRVDG D L V A + A + +
Sbjct: 219 IFICENNRYGMGTSVERAAASTDYYKRGDFIP--GLRVDGMDILCVREATRFAAAYCRSG 276
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+L+E YR HS SD +YR+ EEIQ+ P+ K + + E K
Sbjct: 277 KGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELK 336
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPP 259
E R + Q A +P +E+ +Y PP
Sbjct: 337 EIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPP 374
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 65.7 bits (153), Expect = 1e-09
Identities = 41/153 (26%), Positives = 67/153 (43%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN Y + T ++ A + VDG + A + A N
Sbjct: 169 IFICENNQYGMGTSNDRALANPQVSDFAAAYKMKGYEVDGMNLEASYKAFGEIIADCKKN 228
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
++P L+ YR HS S D+ YR+ +E++ W K++ P+ F +E +G+ D E K
Sbjct: 229 SRPALVNVTTYRYQGHSVS-DAGLYRTKDEVKCW-KEKDPINSFYKSMEEQGWIDEEGYK 286
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A KE + V + A++ P E+ VY
Sbjct: 287 ALDKEMKAEVKDALDFAKESPWPPMDELTNHVY 319
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 65.3 bits (152), Expect = 1e-09
Identities = 44/159 (27%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPAL-GLHTLRVDGTDTLAVHNAVKRARDFTVA 556
+ L +NGYAIS P +Q G I++ A+ GL +DGTD A A++ A +
Sbjct: 185 LYLIEDNGYAISVPIEQQTAGGSISALTAAIPGLFRQEIDGTDFFASWQAMQAAVRYCRE 244
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
+ P L+ A R HS SDD Y++ E + + P+ +F L +G D
Sbjct: 245 GSGPALVHAHCIRPYSHSLSDDERLYKTPAE-RAAEAERDPVLRFPKLLIDEGVLDRRML 303
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPP 259
+ + E + + + Q A + P+ L +Y ++ P
Sbjct: 304 QDITHEIDEEIQQATQTALHDEPPSPASALVHLYSDLDP 342
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 64.9 bits (151), Expect = 2e-09
Identities = 38/155 (24%), Positives = 67/155 (43%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN Y + T ++ G G+ + +VDG D AVH A + A ++ +
Sbjct: 181 IYVIENNRYGMGTSIERASASKDLSRNGEPWGIASRKVDGMDIFAVHEAAQEAMEYCRSG 240
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+E YR HS SD + YR E+++ + P++ K + G + K
Sbjct: 241 KGPFLLEMETYRYRGHSMSDPAK-YRQRAEVEEMRRTRDPIETLKAEMLRSGI-EESVFK 298
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE 268
+ + V + A+ +P+ E+ D+ E
Sbjct: 299 DIETDVKAIVADATEFAQTSPEPDVSELWTDILVE 333
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/152 (30%), Positives = 72/152 (47%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +N ++ +T T+E GDG A+R G+ L VDG D +AV A + A A
Sbjct: 186 LFVCEDNQWSATTRTAEMSAGDGAAARARGFGVPALEVDGMDVVAVWRAARDAVASVRAG 245
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+ A YR H S D +AYR E+ +D+ PL ++ L+ G E
Sbjct: 246 EGPRLLHAKTYRFTGH-VSVDPAAYRDPGELAAAMEDD-PLLVARVRLQASGVAGDAVEA 303
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDV 277
A + AR+ V + A+ + P + E+V
Sbjct: 304 A-MRAAREEVAAAVASADAAEWPTQEAAFENV 334
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 64.9 bits (151), Expect = 2e-09
Identities = 41/157 (26%), Positives = 76/157 (48%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YA+ TP I + A + RVDG D L + A RA + +
Sbjct: 186 VFVCENNLYAMGTPLEVHSSVTEIYRKACAFDMKAERVDGNDVLVMREASLRAVEHARSG 245
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
PVL+EAM YR HS + D+ YR+ E+I++ +++ P+ +++ L ++G + +
Sbjct: 246 KGPVLLEAMTYRFRGHS-AQDTQKYRTKEDIERHRRND-PIVRYRTLLLNEGIATEQQIR 303
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP 262
+ D V ++ A++ +P + + + Y P
Sbjct: 304 DIDRMIDDQVEAAVRFADESPEPGHEWITQAGVYAAP 340
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 63.7 bits (148), Expect = 4e-09
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YA+ST SEQ R ++ RG LG+ ++ DG D +A A++ AR +
Sbjct: 226 VFVVENNQYAVSTHVSEQTRETRLSLRGLGLGIPSITFDGMDVIAARRAMETARKIIETS 285
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSA--YRSVEEIQKW 451
PVL+EA YR H S SA YR E W
Sbjct: 286 GGPVLLEARTYRHLHQSGPLKGSAFGYRDKAEEDAW 321
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 63.3 bits (147), Expect = 6e-09
Identities = 40/153 (26%), Positives = 72/153 (47%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN Y + T T+ +RG + +R+DG + V K A+ + + +
Sbjct: 256 LFVCENNLYGMGTSTARASHNTDFYTRGDKIP--GIRMDGNNYFHVKEGFKFAKQYALEH 313
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+ IE YR HS SD + YR+ EEI+++ + + +Q + + E +
Sbjct: 314 G-PLFIELRTYRYHGHSMSDSGTTYRTQEEIKEFRQKKDCIQFIANTILQNNFATQEQLE 372
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A E R+ V + +++A K P+ E+ DVY
Sbjct: 373 AIQDETREIVDKAVEQALKDPLPDDHELCTDVY 405
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 62.9 bits (146), Expect = 8e-09
Identities = 40/104 (38%), Positives = 57/104 (54%), Gaps = 4/104 (3%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRG-DGIASRGPALG---LHTLRVDGTDTLAVHNAVKRARDFTVANN 550
NN YA+ T + G D +A G + +H RVDG + LAV +A+KR +
Sbjct: 272 NNQYAMGGQTRGETMGYDMLARVGAGVNPEQMHAERVDGYNPLAVIDAMKRKKYLLEQKQ 331
Query: 549 KPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFK 418
PVL++ + YR+ HS S DSS YR+ EE++ W + PL FK
Sbjct: 332 GPVLLDVVTYRLTGHSPS-DSSTYRTKEELEAWA-SQDPLVTFK 373
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 62.5 bits (145), Expect = 1e-08
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I++ +N YA STP S RG A + + VDG D + V++ K+A +
Sbjct: 194 IIVIEDNKYADSTPKSFVMSTTFHYQRGLAYNVPSYLVDGMDVIDVYSTSKKAIERARKG 253
Query: 552 NKPVLIEAMAYR-VGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
P LIEA+ YR VGH D YR+ EE++ W+ + P+++ + L Y D++
Sbjct: 254 FGPTLIEALTYRYVGHF--EGDGEEYRTKEEVEFWSSLD-PIRRLENRLLRLNYADSDIL 310
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+EAR V + A K P + V+
Sbjct: 311 ARLREEARKQVQEAIDFAINSKYPELTDAFGGVF 344
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 61.7 bits (143), Expect = 2e-08
Identities = 41/121 (33%), Positives = 58/121 (47%)
Frame = -1
Query: 663 IASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSS 484
+A R A GL + VDG D AV + +R+ PVLIEA+ YR G HS +D +
Sbjct: 207 LADRASAYGLSAVVVDGNDVAAVFDVARRSIAECRTGGGPVLIEALTYRQGGHSRADPGT 266
Query: 483 AYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKP 304
YR EE++ W P+ ++ +L GY A T A V R ++EA P
Sbjct: 267 -YRPKEEVEAWLA-RDPVTCYREHLLASGY-PAGTLDEIEARATAEVDRAVEEARTAAAP 323
Query: 303 N 301
+
Sbjct: 324 D 324
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 61.3 bits (142), Expect = 2e-08
Identities = 41/109 (37%), Positives = 55/109 (50%), Gaps = 3/109 (2%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN YA+ST E ++SRG A G+ + +VDG D +AV A + A A N P +
Sbjct: 216 NNRYAVSTHVEEVTAEPRLSSRGLAFGIPSFKVDGMDPIAVWLASEEANAIMRAGNGPTI 275
Query: 537 IEAMAYRVGHHSTSDDSSA--YRSVEEIQKWTKDESPLQKF-KLYLEHK 400
IEA YR H + SA YRS +E +W + PL K LE +
Sbjct: 276 IEADVYRYFHQNGPLPGSAFGYRSKDEEAEW-RGRDPLDALAKTLLERQ 323
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 61.3 bits (142), Expect = 2e-08
Identities = 48/158 (30%), Positives = 75/158 (47%), Gaps = 5/158 (3%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I NN YAI T + + ++ + R+DG D V+ AV A+++
Sbjct: 165 IFFCENNYYAIGTRIGWVSPFEELFNKAKNY-MPAKRIDGMDVCEVYKAVTEAKEYLENG 223
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFK-----LYLEHKGYWD 388
P IEA YR HS SD+ YRS EE++ + K P++K K L + + Y+D
Sbjct: 224 LGPYFIEAETYRYEGHSMSDNGK-YRSEEEMEIF-KSRDPIEKLKKEAIALGIVEESYFD 281
Query: 387 AETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
ET+K +E + ++ A +P+ E+ EDVY
Sbjct: 282 -ETDKRVEQE----IAEAIEFAANSPEPDLSELYEDVY 314
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 60.5 bits (140), Expect = 4e-08
Identities = 33/107 (30%), Positives = 52/107 (48%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN YA+ T + + + + G+ T++ DG D +AV +AV+R+ + +PV
Sbjct: 186 NNLYAMGTALARSEAQTDLCMKAASYGMATVQADGMDVVAVFDAVQRSAQQVRSQGRPVF 245
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKG 397
+E YR HS D YR E+Q W K P+ F L+ +G
Sbjct: 246 VELKTYRFRAHSMF-DPELYRDKAEVQAW-KTRGPIHTFTARLKAQG 290
>UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable pyruvate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 344
Score = 60.5 bits (140), Expect = 4e-08
Identities = 41/153 (26%), Positives = 65/153 (42%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN YA + + +Q R +A R G+ + VDG D AV+ + A +
Sbjct: 189 IFICENNLYAEFSSSRDQMRCADVADRAAGYGIPGVVVDGNDPGAVYTTLAAAFERARGG 248
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+EA YR+ H D S YR E+ +W + P+ ++ L + E
Sbjct: 249 GGPTLVEAKTYRLNGHYEGDPQS-YRDKAEVAEWA-ERDPVTCYRARLLQQQNVTEEQLH 306
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+EA D + M EA ++ D+Y
Sbjct: 307 TAEREAADEIRTAMTEALNAPPAGKDDIFGDIY 339
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 60.5 bits (140), Expect = 4e-08
Identities = 47/170 (27%), Positives = 75/170 (44%), Gaps = 5/170 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAV----HNAVKRARDF 565
I + NNGY++ T + G+ +A+R + ++G D V H + RAR+
Sbjct: 196 IFVIENNGYSMGTSQARSSAGE-LATRAAGYDMKWETINGHDLYEVRAKMHALLTRARE- 253
Query: 564 TVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKF-KLYLEHKGYWD 388
KP ++E YR HS +D YR+ +EI+++ K + P+ F + L K D
Sbjct: 254 ---EQKPAVVEIDTYRYRGHSVADPDKTYRTRDEIEEYRKTKDPINLFQQTLLAEKVLTD 310
Query: 387 AETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMK 238
A E+ AR AE P ++ DVY+E Q+ K
Sbjct: 311 ALIEEI-DTAARAEADHAADFAEASPFPTPADIQTDVYWEADNPAQRTSK 359
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 60.1 bits (139), Expect = 5e-08
Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I L NN YA TP ++ R + R A G+ +R+DG D L V ++
Sbjct: 176 IFLCENNTYAELTPIADTVRDAALFKRARAFGMDGVRIDGNDILGVRQCMEHFGQKVRNG 235
Query: 552 NKPVLIEAMAYR-VGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
+ PVLIE M R VGH+ D +YR+ EI + K P+ + L+ G DAE +
Sbjct: 236 HGPVLIEMMTQRLVGHY--IGDMQSYRTAREIAE-AKLHEPIVRLGQRLQLSGVSDAEVQ 292
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 60.1 bits (139), Expect = 5e-08
Identities = 43/153 (28%), Positives = 67/153 (43%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN Y + T RG + L VDG LAV +A + A D + +
Sbjct: 221 IFVCENNHYGMGTHVKRASAMTEFYMRGQYIP--GLWVDGNQVLAVRSATQFAVDHALKH 278
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P+++E YR HS SD ++YRS EE+Q + P+ F+ + D E K
Sbjct: 279 G-PIVLEMSTYRYVGHSMSDPGTSYRSREEVQSTREKRDPITSFRSQIIALCLADEEELK 337
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A + R V ++A ++ E+ D+Y
Sbjct: 338 ALDDKTRKQVDSICKKATTDREVELDELHTDIY 370
>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha; n=58; cellular
organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha - Ralstonia eutropha
(strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 333
Score = 59.7 bits (138), Expect = 7e-08
Identities = 45/157 (28%), Positives = 67/157 (42%), Gaps = 4/157 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNA----VKRARDF 565
I + NNGYA ST D R G+ + VDGTD AVH A ++RAR+
Sbjct: 179 IFVIENNGYAESTSRDYGTAVDSYVDRAAGFGIPGVTVDGTDFFAVHEAAGEVIRRARE- 237
Query: 564 TVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDA 385
P L+E R H D+ YR+ E+ ++ L+ F + G
Sbjct: 238 ---GGGPSLLECKMVRFYGH-FEGDAQTYRAAGELDDIRANKDCLKLFGRAVTQAGVVAR 293
Query: 384 ETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
E +E + +QEA+ +P +++L DVY
Sbjct: 294 EELDTIDREVAALIEHAVQEAKAAPQPGPEDLLTDVY 330
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/159 (25%), Positives = 68/159 (42%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN + TP + + RG A + +RVDG D +A A++ A P +
Sbjct: 210 NNQLGMGTPVEKASAEPDLYKRGCAYRIPGVRVDGNDVIACREALRDALRKAREERAPSI 269
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKE 358
+EA++YR+ HS D + YRS EE Q+ + P+ F+ L G A+ E
Sbjct: 270 LEAVSYRLRGHSVV-DPARYRSKEEAQRLLAHD-PVTAFRQRLIDVGVLSADEAARIDAE 327
Query: 357 ARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQM 241
V ++ A+ P+ E+ Y P + + +
Sbjct: 328 VEAAVDAAVEFADNSPHPSPAELFAHAYAHPLPNMPRAL 366
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 58.4 bits (135), Expect = 2e-07
Identities = 37/119 (31%), Positives = 57/119 (47%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN Y + + + ++ R + G+ + VDG D +A+ +A K A + A
Sbjct: 178 IFVIENNQYGEYSTLASTTPIERLSDRAASYGMPGVFVDGNDVIAMRSATKTAVERARAG 237
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
P LIEA YR HS SD + YR EE++ W P+ + + +E G DA E
Sbjct: 238 EGPTLIEADTYRHSGHSRSDPAK-YRPEEEVKSWFA-RDPIVQLRNAIEASGGADAAAE 294
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 58.4 bits (135), Expect = 2e-07
Identities = 37/108 (34%), Positives = 50/108 (46%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN +AI I + A GL + VDG D LAV A K+A
Sbjct: 193 IFVVENNQWAIGMAHHRSSSIPEIHKKAEAFGLPGIEVDGMDVLAVRQAAKQAVQRARQG 252
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYL 409
+ P LIEA+ YR HS +D RS +E + W P++K K Y+
Sbjct: 253 DGPTLIEALTYRFRGHSLADPDE-LRSRQEKEAWVA-RDPIKKLKKYI 298
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPAL-GLHTLRVDGTDTLAVHNAVKRARDFTVA 556
+ + +NGYAISTP G I+ H DGT+ L + A KRA D+ A
Sbjct: 213 LFVVEDNGYAISTPVEVNTPGGNISKVVSGFPNFHFEECDGTEVLESYRAFKRAIDYIRA 272
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYL 409
P + R HS SDD YR E +K + P+ KF +L
Sbjct: 273 GKGPAFVHGHVIRPYSHSLSDDEKLYRPEAE-RKDEANRDPITKFYKWL 320
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 57.2 bits (132), Expect = 4e-07
Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 3/156 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTP-TSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
+ + NN Y++S+P + Q G I+ R G+ RVDG D AVH A A + +
Sbjct: 164 VYVCENNQYSLSSPLAARQPPGTSISGRARGYGIPAARVDGNDVAAVHAAAVTAVEHCRS 223
Query: 555 NNKPVLIEAMAYRVGHHSTS--DDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAE 382
P +E YR H D R +E+ WTK P+++ L E
Sbjct: 224 GTGPYFLELDTYRWREHVGPGWDHECGARRPDEVLSWTK-RCPIRRAADALRGADPDVDE 282
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
AW +E R + AE P +++L Y
Sbjct: 283 WITAWEREFRAETHAAIAAAEAAPFPRVEDLLVGTY 318
>UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3;
Bacteria|Rep: Dehydrogenase, E1 component - Chloroflexus
aurantiacus J-10-fl
Length = 321
Score = 57.2 bits (132), Expect = 4e-07
Identities = 42/153 (27%), Positives = 63/153 (41%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ NN YA STP S Q IA R + + VDG D AV+ A K A + A
Sbjct: 170 VIICENNQYAYSTPLSRQMAITDIAQRAAGYAMPGVIVDGNDFAAVYRATKEAVERARAG 229
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P IE R+ H+ D+ AY E + +W + P+ + + L +G D
Sbjct: 230 GGPTFIECKTMRMRGHAI-HDNMAYVPKELLAEW-EARDPIARIEEVLRSRGLLDDAKLA 287
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A + AE P+ + + VY
Sbjct: 288 ALLARIEAELDEAQAFAEASPYPDPATLTDGVY 320
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 57.2 bits (132), Expect = 4e-07
Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 1/154 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NNG++ TPTS+ + + +A RG A G+ + + GTD + V ++ A A
Sbjct: 181 IFVVENNGWSELTPTSDMFHAERLAVRGKAYGIPSATISGTDPVVVRDSFAMAAAHARAG 240
Query: 552 NKPVLIEAMAYRV-GHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
N P LIE R+ GH++ D YRS + + T PL L+ G +
Sbjct: 241 NGPSLIECTVPRLWGHYNR--DIEHYRSKADRAEATA-RDPLVLLAARLQQDGVMTDDEV 297
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A K D + P+ + L+ ++
Sbjct: 298 AAIRKSQEDAARALVLRVMASPAPSPADALQPIH 331
>UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3;
Actinomycetales|Rep: Dehydrogenase, E1 component -
Salinispora tropica CNB-440
Length = 323
Score = 56.8 bits (131), Expect = 5e-07
Identities = 38/122 (31%), Positives = 57/122 (46%), Gaps = 3/122 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NNGYA + P ++ G I +R A G+ T VDG D AV A A
Sbjct: 166 LFVCENNGYATTMPVADAVAGS-IPARAEAFGIRTSVVDGQDPAAVQATTAAALTRMRAG 224
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSA--YRSVEEIQKW-TKDESPLQKFKLYLEHKGYWDAE 382
P +EA YR H T + + YRSVEE+++ ++D + +L + DA+
Sbjct: 225 GGPEFLEAQTYRFDAHHTFEHAVRLDYRSVEEVERGRSRDPVRIAGSRLSATERAKVDAD 284
Query: 381 TE 376
E
Sbjct: 285 VE 286
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 55.6 bits (128), Expect = 1e-06
Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIA--SRGPALGLHTLRVDGTDTLAVHN-AVKRARDFT 562
I + NN +AI +S D + S+G A + T +VDG D L ++ A K+ +
Sbjct: 388 IFVIENNNWAIGMESSRSSSDDLMNNYSKGKAFNIDTFKVDGNDVLTIYKLAKKKIQQIR 447
Query: 561 VANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAE 382
+ P++IEA+ YR HS +D R EE W K P+ Y++
Sbjct: 448 NRTSGPIIIEAITYRAKGHSLADPDE-LRIKEEKTSW-KKRDPILFLSSYMKKYNL---- 501
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKE 292
++++ ++ + +Q+AE + N K+
Sbjct: 502 VQESYFEQVKKNTQTLLQQAELDAEQNTKK 531
>UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha
subunit; n=2; Bacteria|Rep: Putative pyruvate
dehydrogenase alpha subunit - Streptomyces coelicolor
Length = 323
Score = 55.2 bits (127), Expect = 2e-06
Identities = 28/82 (34%), Positives = 45/82 (54%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ +NG A STPT Q G +A+R A G+ LR+D D V A+ +
Sbjct: 188 LVVVEHNGIAQSTPTERQMSGT-VAARAAAFGVGHLRIDSVDVTDVRAALTPVVEQVRDR 246
Query: 552 NKPVLIEAMAYRVGHHSTSDDS 487
++P ++E + +RVG HS DD+
Sbjct: 247 HRPYVVECVTHRVGPHSKGDDT 268
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 55.2 bits (127), Expect = 2e-06
Identities = 46/153 (30%), Positives = 64/153 (41%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + +NN YA TP E D IA R A L + VDG D + ++NA A +
Sbjct: 184 IFVCQNNRYAEYTPLREGTSVDRIAQRAAAYSLPGVTVDGNDPIELYNAAGAAIERARTG 243
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P L+EAM +R H D Y EE++ + PL +F+ L D
Sbjct: 244 GGPTLLEAMTFRFCGH-IMGDQQVYMPPEELRAAIAAD-PLVRFRAQLAADVGEDELA-- 299
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A + A D V + A + P + DVY
Sbjct: 300 AVERAAADEVADAWEFARTAELPAASALTTDVY 332
>UniRef50_Q6MP90 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=5; Deltaproteobacteria|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 376
Score = 54.0 bits (124), Expect = 4e-06
Identities = 26/83 (31%), Positives = 44/83 (53%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
++ +NNGY ISTP Q+ IA R A + + ++G D + + A+K ++
Sbjct: 222 LITVQNNGYGISTPYEGQHGETNIADRAAAFNIRSRVINGNDPIETYLALKEEMEYIRKT 281
Query: 552 NKPVLIEAMAYRVGHHSTSDDSS 484
KP IEA R+ HS++D ++
Sbjct: 282 GKPSFIEAKVTRLYGHSSADGAN 304
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 54.0 bits (124), Expect = 4e-06
Identities = 39/152 (25%), Positives = 63/152 (41%), Gaps = 4/152 (2%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN YA+ T RG + +R + AV K + + P+
Sbjct: 220 NNKYAMGTSIERHAHNLNFYKRGDLIP--GVRCQANNVFAVRELYKWGKKYCTDGKGPLF 277
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLY-LEHKGYWDAETE---KA 370
E YR HS SD YR+ EE+ ++ K + P+ K + LEH D TE K
Sbjct: 278 FELQTYRYHGHSMSDPGITYRTREEVNEYRKTQDPILLVKKWILEH----DIATEKYLKE 333
Query: 369 WSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
KE R + +++ + P +E++ ++Y
Sbjct: 334 IDKEIRARIDEEVEQIKNDPMPAPEELMTEIY 365
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 54.0 bits (124), Expect = 4e-06
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
Frame = -1
Query: 588 AVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYL 409
AVK R+F A N P++ E + YR HS SD YR+ E+ K + P+ F+ L
Sbjct: 236 AVKHGREFIRAGNGPLVYEYVTYRYAGHSMSDPGVGYRTRGEL-KAERASDPVSNFRAQL 294
Query: 408 EHKGYWDAETEKAWSKEARDTVVRTMQEAEK--KKKPNWKEMLEDVY 274
G + K K R V + EAEK + +P + +D+Y
Sbjct: 295 IDWGIITEDEAKTIDKNVRKKVNHEVAEAEKMPEPEPRLDVLFQDIY 341
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 53.6 bits (123), Expect = 5e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ NN YA STPTS G+ I R G+ ++ D D + ++ K A D N
Sbjct: 170 LVVLENNQYAQSTPTSLTLAGN-IRDRVRGFGIEYIKCDTWDIAGLLDSAKEAVDCVRKN 228
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDES 436
KPVL+E YR+ HS DD R EI ++ +S
Sbjct: 229 QKPVLLEIDTYRLKAHSKGDD---LRDPVEISRYAGQDS 264
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 52.0 bits (119), Expect = 1e-05
Identities = 42/156 (26%), Positives = 61/156 (39%), Gaps = 3/156 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NNGY++ T + I + GL T DG D L V + A + T
Sbjct: 176 IFVCENNGYSVYTRLEARQPERTIRGIAQSHGLETYHGDGNDVLNVTALAREAINRTRRG 235
Query: 552 NKPVLIEAMAYRVGHH--STSDDSSAYRSVEEIQKWTKDESPLQKFK-LYLEHKGYWDAE 382
P +E YR H DD+ YR E+ W K P+++FK L LE + E
Sbjct: 236 EGPQFLELDTYRWLEHCGPNDDDNLGYRPAGELMSW-KKRCPVEQFKNLLLESQKVTHTE 294
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
++ E + A + P M + VY
Sbjct: 295 IQQV-ENEVLHEIEAAFSYALESPNPTSASMADKVY 329
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 50.8 bits (116), Expect = 3e-05
Identities = 32/153 (20%), Positives = 66/153 (43%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YA+ T + + G G D +V+ AV+ + N
Sbjct: 311 VFVCENNQYAMGTAVDRAFSKPDLFKHGYNFDFPASLASGMDVFSVNKAVQDHVENYARN 370
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
++P L+E YR HS +D + YR E+ + + + + + + Y+ +G +
Sbjct: 371 DQPSLLEVRTYRYQGHSITDPAE-YRGEGELDQ-RQSQDAINRLQDYILDRGLATEADME 428
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A +E ++ V + A + P+ + + +D+Y
Sbjct: 429 AIDEEVKERVKDAIDAANEASFPDEEAIYDDIY 461
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 50.4 bits (115), Expect = 4e-05
Identities = 36/154 (23%), Positives = 61/154 (39%), Gaps = 1/154 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN + E + ++ G G+ VDG D AV A + A
Sbjct: 169 LYICENNQWQAFVHRREAMSSEHVSDWGAGYGIPARTVDGNDVFAVLEATREAATQVRDT 228
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKW-TKDESPLQKFKLYLEHKGYWDAETE 376
+PVL+E + YR H DD Y E+ W +D L + +L + G+ D +
Sbjct: 229 RRPVLLEVLTYRTRGHFEPDD-QGYVDKAELAAWLARDPIALCRDRLIAD--GHLDVAAD 285
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+ ++ + A P+ +E+ DVY
Sbjct: 286 AELAARVEASIAAAVAFAAASPFPSIEELTLDVY 319
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/157 (22%), Positives = 69/157 (43%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + NN Y++ TP + I +R G+ R + TD V + A
Sbjct: 182 IYIVENNRYSMGTPLERTLPTEDITARAAGYGMARDRFELTDPFQVRERIGAAMKRAREE 241
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
++P LIE + YR HS SD + YR+ E++ + ++ ++ +E G + E +
Sbjct: 242 SQPTLIEILTYRFRGHSMSDPAK-YRAKGELEAFRSRDAIELSRRVLMEQHGMSEDELD- 299
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP 262
A E + + A++ +P+ + +++ +P
Sbjct: 300 AIDDEVIEEMDAAYTFADESPQPDPEHRFKNIMIPVP 336
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 50.0 bits (114), Expect = 6e-05
Identities = 37/152 (24%), Positives = 65/152 (42%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NNGY + TP S RG A+ +R+ + + + +K AR ++V N
Sbjct: 202 VFVCENNGYGMWTPASSVSADTDFYLRGGAIP--GIRIGHGNIFGLMSVLKYARKYSVEN 259
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P++++ YR HS +D+ +YRS EE+ K + + L ++ E
Sbjct: 260 G-PIIVQIDTYRFCTHSAADERESYRSREEVDAEKKRDCMEDVGRRLL---AFYSEEELD 315
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDV 277
A V R + A K + E+ D+
Sbjct: 316 ALRSSILAEVERDVDAARKSRPTEEDELCRDI 347
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 50.0 bits (114), Expect = 6e-05
Identities = 44/162 (27%), Positives = 70/162 (43%), Gaps = 5/162 (3%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVH----NAVKRARDF 565
+ + +N +AIS P A R L +R+D D AV+ AV RARD
Sbjct: 176 VFVVEDNDWAISMPKDRVTDVQNGAQRAAGFDLPGVRIDSDDATAVYEAAGEAVMRARD- 234
Query: 564 TVANNKPVLIEAMAY-RVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWD 388
N P LIE + R+GH D+ AYR +I + K +++ L G D
Sbjct: 235 ---GNGPTLIEVQVHRRMGHF--MGDAEAYRPEADIDR-AKQRDSIERLAADLRSHGVTD 288
Query: 387 AETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP 262
+ ++ + A V + A+++ +P E E+V+ P
Sbjct: 289 DDIDE-MRERAHGRVEAAISWAKEQPEPEPAEAYENVFTNPP 329
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 49.6 bits (113), Expect = 8e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ +NN Y TPT + +A R G+ +RVDG D LAV + +A + +
Sbjct: 174 VLVCQNNQYGEMTPTEHTMKIAQVADRAGGYGMPGVRVDGNDPLAVLAVLTQAVERARSG 233
Query: 552 NKPVLIEAMAYRV-GHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWD 388
P L+E + +R GH+ D AY E + + P+ +F+ L G D
Sbjct: 234 GGPTLVECVTFRFRGHY--FGDPMAYIPAERMAA-AVEADPIPRFRSRLLETGVCD 286
>UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 167
Score = 49.6 bits (113), Expect = 8e-05
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 5/168 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAV----HNAVKRARDF 565
+ + NN YA+ T I G + + + VDG D L + +NA+ RAR+
Sbjct: 5 VFICENNRYAMGTSVKRSSNIKDIYKIGFSYKMPSFCVDGMDPLKIYEHAYNAISRARN- 63
Query: 564 TVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDA 385
N P ++ + YR HS + D+ YRS +E+ + +K+ P+ K ++
Sbjct: 64 ---GNGPTFLDILTYRYRGHSMT-DAETYRSKKEVNE-SKNRDPILLIKKFILKNKIVTE 118
Query: 384 ETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP-PRLQKQ 244
+ ++ E + ++ AE N +++ VY + P L+K+
Sbjct: 119 KVLNSFQDEINKKINECVKFAELSDSTNIEKLYSVVYNQKDYPFLEKK 166
>UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 327
Score = 49.6 bits (113), Expect = 8e-05
Identities = 39/152 (25%), Positives = 61/152 (40%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I + +NN YA T + R D A R + +RVDG D ++ A + A D A
Sbjct: 172 IFVCQNNAYAEHTSMARSTRVDSYAKRAAGYAMEGIRVDGNDPDEMYGAARWAIDRARAG 231
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P IEA +R H ++ Y +E+ ++ P+ + L +G A
Sbjct: 232 EGPTFIEATTFRFNGHLIG-EAGGYMD-KELYAASQTRDPMPILRRRLVDQGIAAAGELD 289
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDV 277
A R + +Q A P+ E+ DV
Sbjct: 290 ALDASIRAEIDAAVQAAYAADYPDPSELKVDV 321
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 1/154 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIAS-RGPALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
I + NN + + T + +A + + +DG D + + +
Sbjct: 185 IYVIENNQWGMGTAIQKAVSVKRLAEDKASGYNMKAYTLDGMDFFNCYGGFAQIHQEVLQ 244
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
+PVL+E + R HS S D YR+ + + K + P+ + L KG +
Sbjct: 245 RQRPVLVEVVTERFKGHSIS-DPGLYRAKDTL-KQIMAKDPILALQAVLIKKGILTEDMV 302
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
K +KE R+ ++ M AE P+ + + EDV+
Sbjct: 303 KQMNKENREKIIEAMSFAENSPWPDPQTLEEDVF 336
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 49.2 bits (112), Expect = 1e-04
Identities = 44/156 (28%), Positives = 57/156 (36%), Gaps = 3/156 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTS-EQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
+ L NNGY++ +P S Q G + GL T DG D AVH A+ A
Sbjct: 165 LFLCENNGYSVYSPLSVRQPPGRRLYEMVAGFGLPTHHGDGNDARAVHAALSEGVAAIRA 224
Query: 555 NNKPVLIEAMAYRVGHH--STSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAE 382
P E YR H D+ YRS E + W K P+ + L +G
Sbjct: 225 GEGPRFYEFETYRWREHCGPNYDNDIGYRSAAEYEAW-KLRDPVPALQRALIGEGVVSES 283
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
A E + AE P+ E DVY
Sbjct: 284 GIAAMQAEIDAEIDEAFAFAEASPFPDAGEAFTDVY 319
>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
dehydrogenase alpha and beta fusion); n=7;
Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion) -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 678
Score = 48.0 bits (109), Expect = 2e-04
Identities = 34/102 (33%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPA-LGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
I + +NN +AIS P +Q D +AS G GL VDG + ++ A D
Sbjct: 175 ITVIQNNHWAISVPFEDQCGAD-LASLGRCHQGLAVYEVDGGNYTSLTETFSHAVDQARQ 233
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPL 430
++ P LI R+ HS SD+ YRS ++ K + D+ PL
Sbjct: 234 HSVPALILIDVVRLSSHSNSDNQEKYRSALDL-KLSMDKDPL 274
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 46.8 bits (106), Expect = 5e-04
Identities = 43/161 (26%), Positives = 66/161 (40%), Gaps = 2/161 (1%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YAI T R A + + G D V A + A +
Sbjct: 171 LFVCENNCYAIGTVIQRSTAVIDQYKRLEAYNIPASQHPGQDIEVVMEAAQSAIAHVRSG 230
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P +E + YR HS SD + AYRS EE+ +W + P+Q L G E K
Sbjct: 231 AGPYFLEFLTYRYRGHSMSD-AGAYRSKEEVAEWMQ-RDPIQILAKRLIEAGELTEEEFK 288
Query: 372 AWSKEARDTVVR-TMQEAEKKKKPNWKEMLEDVYYEMP-PR 256
A + + + +Q AE+ +P ++ + V + P PR
Sbjct: 289 AMEQAVQSEIDNDIIQFAEESPEPKVADLAKYVLEDNPDPR 329
>UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5;
Eukaryota|Rep: Pyruvate dehydrogenase E1 componen -
Arabidopsis thaliana (Mouse-ear cress)
Length = 127
Score = 46.8 bits (106), Expect = 5e-04
Identities = 29/105 (27%), Positives = 46/105 (43%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I++ NN Y + T + RG + L+VDG D V A K +
Sbjct: 20 ILVCENNHYGMGTXEWRAAKSPSYYKRGDYVP--GLKVDGMDAFPVKQACKFPKQHXXEK 77
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFK 418
P+++E YR HS S S YR+ +EI ++ P+++ K
Sbjct: 78 G-PIILEMDTYRYHGHSMSXPGSTYRTRDEISXVRQERDPIERIK 121
>UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter
violaceus|Rep: Gll1094 protein - Gloeobacter violaceus
Length = 481
Score = 46.4 bits (105), Expect = 7e-04
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 1/154 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGD-GIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
I + +N Y IST T Q GI + + RVDG + N +A
Sbjct: 170 IFVVEDNAYGISTSTKHQLPFRLGIFNEEIFV-----RVDGRHPAEIFNHSGQAITKARQ 224
Query: 555 NNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
N P ++ R+ H+ SDD YR EEI + PL +L + G A
Sbjct: 225 GNGPTILWVELDRLVSHTNSDDHRIYRPKEEIDAMLQ-RDPLSVLARHLINAGELTATEW 283
Query: 375 KAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVY 274
+A + T+ Q+AE++ PN ++L +Y
Sbjct: 284 QALQFKTAMTIDEIYQQAERENSPNPDQILVHLY 317
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 46.4 bits (105), Expect = 7e-04
Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 3/171 (1%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN Y + T + R R A GL+ VDG D V A + D A KP
Sbjct: 175 NNQYGMGTRIDQATRNTAFDQRAKAFGLNGAVVDGLDVEEVQAAARWLVDEARA-GKPGF 233
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLY---LEHKGYWDAETEKAW 367
+ YR H+ D S EE++ KD + KL +E + D E +KA
Sbjct: 234 LSVEVYRFFGHARMDKSPYREEAEELEGRKKDPVLFARNKLIDTGIEEERILD-ELDKAI 292
Query: 366 SKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
+ E + T+ A + K P M +DVY P + +++ L +
Sbjct: 293 AAE----MDATIDFAVESKAPPLGSMFKDVYAAGEPEPESVRARIDRVLAR 339
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 45.2 bits (102), Expect = 0.002
Identities = 39/174 (22%), Positives = 70/174 (40%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN YA +TP G +A R + G+ +++ D + ++ ++ D+
Sbjct: 176 LFILENNRYAQTTPNELGISGSMLA-RPKSFGIEADQIESNDAVELYQVFEKRFDYVRNK 234
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
KP YR HS DD +R EI W K K + + K D ET+K
Sbjct: 235 RKPFFQIIDTYRTVPHSKGDD---FRDQAEIDAWKK------KDPVIILGKNVSD-ETKK 284
Query: 372 AWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKY 211
E + ++EA+ + + + + + P+ + Q+ KKY
Sbjct: 285 TVMAEVTSDIQNAIKEAKDAEYTSENNIEYENIITISPKNENQLLNNLPRAKKY 338
>UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12;
Bacteria|Rep: Pyruvate dehydrogenase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 344
Score = 44.0 bits (99), Expect = 0.004
Identities = 30/118 (25%), Positives = 48/118 (40%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + +N + IS P + A R A G+ R++G D V++A +RA A
Sbjct: 195 VFVVEDNDWGISVPRTASTSVASNADRAAAYGIPGERIEGNDVEGVYDAARRAVARARAG 254
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAET 379
P LIE R+ H D +E+ P+ +++ L G D ET
Sbjct: 255 EGPSLIEVHTLRLWGHFEGDAQGYRLDLED----APSHDPIPRYETRLREAGVLDDET 308
>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component; n=4;
Bacteroidetes|Rep: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 946
Score = 42.3 bits (95), Expect = 0.012
Identities = 28/131 (21%), Positives = 60/131 (45%)
Frame = -1
Query: 627 LRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWT 448
+ V+G D AV ++ A ++ N+ + I+ + YR H+ SD+ + + +
Sbjct: 424 MHVNGDDPEAVTFCMRLAAEYRQKFNEDIFIDMVCYRRHGHNESDEPK-FTQPKLYNVIS 482
Query: 447 KDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE 268
+ +P + + L +G DAE K +E RD + + + ++K P + +E + E
Sbjct: 483 RHANPRELYNQKLIERGDVDAEIAKNMDREFRDMLQDRLNQVKQKPLPYSLQKMEKEWTE 542
Query: 267 MPPRLQKQMKQ 235
+ ++ Q
Sbjct: 543 LRKATKEDFDQ 553
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 41.9 bits (94), Expect = 0.016
Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPAL--GLHTLRVDGTDTLAVHNAVKRARDFTV 559
+ L +N Y ISTPT DG++ + L T VDG+D AVH A
Sbjct: 193 VFLVSDNRYGISTPT------DGLSPQRLGLMPDAITKVVDGSDPDAVHAAAAAVLPDVR 246
Query: 558 ANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEI 460
A P ++ R+ H++SDD YR+ +E+
Sbjct: 247 AGRGPAVLWCRLDRLDSHTSSDDQRLYRTKDEL 279
>UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1;
Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase, E1 component -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 324
Score = 41.1 bits (92), Expect = 0.027
Identities = 23/80 (28%), Positives = 39/80 (48%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ + NN +A ST S+ +A + G+ ++ VDG + V++ A ++T
Sbjct: 191 VFICENNQFAQSTKLSD-ISLTSVAKKSQGFGIKSIEVDGLNISEVYSKTSDAVNYTRNE 249
Query: 552 NKPVLIEAMAYRVGHHSTSD 493
KP LI+A YR H S+
Sbjct: 250 IKPYLIQANTYRFHRHFVSE 269
>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
signal; n=2; Proteobacteria|Rep: Twin-arginine
translocation pathway signal - Mesorhizobium sp. (strain
BNC1)
Length = 375
Score = 41.1 bits (92), Expect = 0.027
Identities = 22/53 (41%), Positives = 27/53 (50%)
Frame = -1
Query: 663 IASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHH 505
IA G+ + VDG D + V+NA K A D A P LIEA YR +H
Sbjct: 221 IADAANTYGIPGIVVDGQDVIQVYNAAKTAVDRARAGEGPTLIEAKTYRYYNH 273
>UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Dehydrogenase, E1 component - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 315
Score = 40.7 bits (91), Expect = 0.036
Identities = 28/94 (29%), Positives = 40/94 (42%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I NNG + T T + IA+ G+ + VDG D +AV A + A A
Sbjct: 170 IYFCENNGLLVGTRTEQVSATADIANLAKGYGIPGVIVDGQDAVAVWEATREAAARARAG 229
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKW 451
P LIEA R H + D YR + ++ +
Sbjct: 230 KGPTLIEAKVTR-KHGHYAGDPQHYRDPDYLRDY 262
>UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit; n=1; Plesiocystis
pacifica SIR-1|Rep: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit - Plesiocystis
pacifica SIR-1
Length = 757
Score = 39.5 bits (88), Expect = 0.083
Identities = 39/167 (23%), Positives = 72/167 (43%), Gaps = 10/167 (5%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRG-DGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVA 556
+++ +N AIS T E RG I + A G DG D + ++ KRA +
Sbjct: 195 LIIITDNNVAISV-TPEDGRGIRDIEAYAKAFGFEYFTADGNDFIDIYETTKRAATYCRD 253
Query: 555 NNKPVL--IEAMAYRVGHHST---SDDSSAYRSVEEIQKWTKDESPLQKFKLYL---EHK 400
N +P L I+ ++ GH + + D A+ + + + + L+ + E +
Sbjct: 254 NQRPALFWIQNLSRLNGHSNAGVYNFDFDAHDVLTDFGEALVERGILEPEDIIRRNDEPR 313
Query: 399 G-YWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP 262
G Y+ T KE D +V TM+ + + +P ++ + E + P
Sbjct: 314 GEYFKRHTLGRVGKECDDYIVETMRIVDGEPEPTYESVFEHIRTPYP 360
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 39.1 bits (87), Expect = 0.11
Identities = 33/137 (24%), Positives = 62/137 (45%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+++ NN YA ST SE G I+ R A G+ + D + + + ++T
Sbjct: 159 LIVLENNQYAQSTHISETLSGS-ISKRAQAFGMRYTKSDVWNWEHLIAETEELINYTRNQ 217
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEK 373
P ++ YR+ HS DD R+++EI+ + + + + L + + ETE
Sbjct: 218 RHPAFLQIDTYRLKAHSKGDD---LRNIDEIEHF----NTIDPINVILRERAA-ELETEV 269
Query: 372 AWSKEARDTVVRTMQEA 322
A +E + +R ++A
Sbjct: 270 AGVQERVNDAIRKAKQA 286
>UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG18255-PA - Nasonia vitripennis
Length = 2871
Score = 38.7 bits (86), Expect = 0.15
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Frame = -1
Query: 471 VEEIQKWTKDESPLQKFKLYLEHKGYWDAET---EKAWSKEARDTVVRTMQEAEKKKKPN 301
+EE ++ KDE+ K K +EHK +AE E+ K+ + ++E E+KKK
Sbjct: 1561 LEEEERKKKDEAEKLK-KKEVEHKKKEEAEKLRLEEEERKKKEEVEKLRLEEEERKKKKE 1619
Query: 300 WKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHESD 175
+++ ++ +++K+ EE LKK E L + E +
Sbjct: 1620 AEQLKKEQVEHKKKEEAEKLKKKEEELKKKEESEKLKKEEDE 1661
>UniRef50_A5KBR9 Cluster: Nucleosomal binding protein 1, putative;
n=1; Plasmodium vivax|Rep: Nucleosomal binding protein
1, putative - Plasmodium vivax
Length = 506
Score = 38.3 bits (85), Expect = 0.19
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = -1
Query: 483 AYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKP 304
A + E+ K K+E+ +K K E K +AE + KE D + + ++AEKK+K
Sbjct: 124 AQKIKEQEVKLRKEEAKAEKKKKEKEKKLKKEAEKAEKKRKEKEDKLKKEAEKAEKKRKA 183
Query: 303 NWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
N +++ ++ + +K+ K EE +KK
Sbjct: 184 NEEKLKKEA-----EKAEKKRKANEERMKK 208
>UniRef50_Q0UJ30 Cluster: Putative uncharacterized protein; n=2;
Eukaryota|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 1604
Score = 37.9 bits (84), Expect = 0.25
Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 3/110 (2%)
Frame = -1
Query: 534 EAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEA 355
E A S D+ A + EE K ++ QK + K D E +K E
Sbjct: 780 EKQAKETSDASVKADADAKQKAEEEAKAKAEQESKQKEEAEAADKAKVDEEEKKRLEDEE 839
Query: 354 RDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQK---QMKQMEEHLKK 214
+ ++ M+E EKK++ + K E+ + K ++K+ EE L+K
Sbjct: 840 MERMIAEMEEEEKKREADEKRYAEEKKKKAEEEKAKAGDRVKEEEERLRK 889
>UniRef50_Q234R7 Cluster: Viral A-type inclusion protein repeat
containing protein; n=2; Eukaryota|Rep: Viral A-type
inclusion protein repeat containing protein - Tetrahymena
thermophila SB210
Length = 4039
Score = 37.5 bits (83), Expect = 0.33
Identities = 22/92 (23%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Frame = -1
Query: 480 YRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPN 301
+ +++ QK K + +QK + YL + D E ++ K+ D + M++ E+ +
Sbjct: 2179 FENIQNSQK--KQKKKIQKEESYLNQESGNDLEDQERQIKQLEDAYQKLMEQHERNQTEQ 2236
Query: 300 WKEM---LEDVYYEMPPRLQKQMKQMEEHLKK 214
+EM +++ ++ LQKQM+ M+E ++
Sbjct: 2237 QQEMKRQYDNIEEQIRENLQKQMQLMQEKYER 2268
>UniRef50_A3HUN2 Cluster: Putative uncharacterized protein; n=1;
Algoriphagus sp. PR1|Rep: Putative uncharacterized
protein - Algoriphagus sp. PR1
Length = 298
Score = 37.1 bits (82), Expect = 0.44
Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 6/111 (5%)
Frame = -1
Query: 510 HHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYL---EHKGYWDAETEKAWSKEARDTVV 340
H ++ D S R +E+ + W + + + ++Y H +WD ++ + VV
Sbjct: 79 HDASYKDVSKERVLEQWKVWDLFRAGISEDEVYSCIGNHDPWWDVPNKEEEPMYGKPYVV 138
Query: 339 RTM---QEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYP 196
+ + E K NW ++ D YE ++QMK +E+ L+K P + P
Sbjct: 139 KRLGMPAEYYSFDKGNWHFIILDGNYEGISLGEEQMKWLEKDLEKLPANTP 189
>UniRef50_Q9N437 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1037
Score = 37.1 bits (82), Expect = 0.44
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Frame = -1
Query: 516 VGHHSTSDDSSAYRSVEE-IQKWTKDESPLQKFKLY-LEHKGYWDAETEKAWSKEARDTV 343
+G HS V++ +Q++ +D+ P+ + LE + D RD +
Sbjct: 928 IGIHSPDGGIDKEEDVDDLVQRFERDQEPVHSAREEELEDQKVLDELRADVMCPPTRDMI 987
Query: 342 VRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHE 181
+EAEK K+ KE+ ++ YYE + QK K+ +E +K P+ PL+ E
Sbjct: 988 ----EEAEKLKELKKKEIPKESYYEKLLKRQK-AKEDDEKTEKKPKLEPLDTME 1036
>UniRef50_UPI0000DB76E3 Cluster: PREDICTED: similar to Posterior sex
combs CG3886-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Posterior sex combs CG3886-PA - Apis
mellifera
Length = 966
Score = 36.7 bits (81), Expect = 0.59
Identities = 19/44 (43%), Positives = 28/44 (63%), Gaps = 3/44 (6%)
Frame = -1
Query: 315 KKKPNWK--EMLEDVYYEMPPRL-QKQMKQMEEHLKKYPEHYPL 193
K KPN K + L+D+ Y++ P L K+M++ E KK+PEH L
Sbjct: 103 KAKPNIKADKALQDIVYKLVPGLYHKEMRKRREFYKKHPEHADL 146
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 36.7 bits (81), Expect = 0.59
Identities = 27/106 (25%), Positives = 42/106 (39%), Gaps = 6/106 (5%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
++L NG A STP G + R A G+ D + + AV D
Sbjct: 166 VVLVEANGIAQSTPVDTVQAGSAVG-RARAFGIEARESDTWNPEDLLRAVSATVDTARRE 224
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSA------YRSVEEIQKWTKDESP 433
+P+L +R+ HS DD+ A YR + + +W + P
Sbjct: 225 GRPLLHLVRTFRLMPHSKGDDTRAPDLIEEYRLKDPVTQWLAEGGP 270
>UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7;
Mycobacterium tuberculosis complex|Rep: Dehydrogenase E1
component - Mycobacterium tuberculosis (strain ATCC
25177 / H37Ra)
Length = 334
Score = 36.7 bits (81), Expect = 0.59
Identities = 26/88 (29%), Positives = 37/88 (42%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
++L N A+S + R A G+ + VDG D AV + V A A
Sbjct: 176 VILVENIRGALSVHLDRYTHEPRVYRRAVAYGMPGVSVDGNDVEAVRDCVANAVVRARAG 235
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSV 469
P L++A+ YR S S D YR +
Sbjct: 236 GGPTLVQAITYRTTDFSGS-DRGGYRDL 262
>UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha and Beta Fusion; n=6; cellular organisms|Rep:
(Pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta
Fusion - Dokdonia donghaensis MED134
Length = 693
Score = 36.7 bits (81), Expect = 0.59
Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L ++NG+ IS +E + GL + +DGTD + +++
Sbjct: 189 LYLVQDNGWDISANAAETRAQNAFEYAQGFHGLEAVTIDGTDFEESYTTLEKVIKTIRTE 248
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYR-SVEEIQKWTKDESPLQKFKLYLEHKGYWDAETE 376
+P L+ A + HH++ YR +EE Q P K L + G+ E E
Sbjct: 249 RRPFLVHAKVPLLNHHTSGVRMEWYRDDLEEAQ----SRDPYPKMIELLLNNGFDKKEIE 304
Query: 375 KAWSKEARDTVVRTMQEAEKKKKP 304
+ + A+ V + +A++ + P
Sbjct: 305 E-MTAFAKAEVQKDFDKAQQAEDP 327
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 36.7 bits (81), Expect = 0.59
Identities = 36/147 (24%), Positives = 64/147 (43%)
Frame = -1
Query: 717 NNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVL 538
NN Y++ T ++ D R L LRV G AV ++ +R+ + P++
Sbjct: 200 NNAYSMWTCVADACANDDFYKRADFLP--GLRVLGRSIFAVTRCLEVSREHALQKG-PLI 256
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKE 358
++ YR+ HST+ D YR E+++ ++ + L + L + + AE A +
Sbjct: 257 VQIDTYRLCGHSTT-DGIVYRDETEVRR-ERERNALGHTESALVQR--FGAEHIAAIKAD 312
Query: 357 ARDTVVRTMQEAEKKKKPNWKEMLEDV 277
R V + A +P E+ DV
Sbjct: 313 VRSHVAHEVDVALAMLEPEPTELFRDV 339
>UniRef50_Q9VR26 Cluster: CG3294-PA, isoform A; n=4; Sophophora|Rep:
CG3294-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 446
Score = 36.3 bits (80), Expect = 0.77
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Frame = -1
Query: 465 EIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEML 286
E QKW++++ +Q+F+ + + AE E +EA M EA+K+++ E L
Sbjct: 43 EYQKWSQEQEEMQEFQRLADERERQLAE-ESWLRREATAQRQFQMDEAKKRQEQEEVERL 101
Query: 285 E-DVYYEMPPRLQKQMKQMEEHLKK 214
+ + E R ++Q KQ EE +K
Sbjct: 102 QREQAKERAEREERQRKQREEETRK 126
>UniRef50_A7SQM2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 422
Score = 35.9 bits (79), Expect = 1.0
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = -1
Query: 573 RDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGY 394
RD + N K ++ +A D+ R ++E K +K ES + +K LE
Sbjct: 277 RDVEILNEKNEQLQGLAEE--SQQLKDEMDVLRHMQE--KVSKYESTIDMYKKKLEELSD 332
Query: 393 WDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYE--MPPRLQKQMKQMEEHL 220
+ KA ++ + TM E KK N + D Y + M + + +MK MEE
Sbjct: 333 MRKQM-KAMEEKNVTYMQETMNLEEDLKKANALKTQLDTYKKQSMLSKKESEMKAMEERY 391
Query: 219 KKYPE 205
K+Y E
Sbjct: 392 KRYLE 396
>UniRef50_Q2H0S6 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 254
Score = 35.9 bits (79), Expect = 1.0
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 4/120 (3%)
Frame = -1
Query: 522 YRVGHHSTSDDSSAYRSVEEIQK--WTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARD 349
+RVG + D + R V +I+K TK + Q K+ EH+ A T + +K +
Sbjct: 34 FRVGPENLPDGAWR-RKVTKIKKDLITKAKVKKQYAKIKAEHQKQASAPTPEDHTKNNAE 92
Query: 348 TVVRTMQEAEKKKKPNWKEMLED--VYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHESD 175
+ QE E +P ++ + + P L K Q ++ ++ +H P ++ E+D
Sbjct: 93 PTIHPDQEGEDSTEPAPAQIHPERQAMLDAPSSLSKPPAQRQQRQRQQQQHQPTDETEAD 152
>UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-Mlck
CG18255-PA, isoform A; n=2; Coelomata|Rep: PREDICTED:
similar to Stretchin-Mlck CG18255-PA, isoform A - Apis
mellifera
Length = 3978
Score = 35.1 bits (77), Expect = 1.8
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Frame = -1
Query: 459 QKWTKDESPLQKFKLYLEHKGYWDAETEKAWS-KEARDTVVRTMQEAEKKKKPNWKEMLE 283
+K K++ +K K E K +AE K ++ ++ + QE E+KKK +++ +
Sbjct: 2512 EKERKEKEEAEKLKQEEERKKKEEAEKLKQEEERKEKEKAEKLKQEEERKKKEETEKLKQ 2571
Query: 282 DVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHE 181
+ + +K +KQ EEH KK E L Q E
Sbjct: 2572 EEERKKKEETEK-LKQKEEH-KKKEEAEKLKQEE 2603
Score = 33.1 bits (72), Expect = 7.2
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = -1
Query: 477 RSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNW 298
R +EE +K ++E +K K E K + EK K + +++ QE E+KKK
Sbjct: 2408 RKIEEAEKLKQEE---EKHKKEEETK---KLKQEKEEQKRKEEEILK--QEEEQKKKQEE 2459
Query: 297 KEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHE 181
+E L+ +K + EEH K+ E L + E
Sbjct: 2460 EEKLKQEEERRKQETEKLCLEEEEHKKREIEKLKLEEEE 2498
>UniRef50_Q2BCS0 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 463
Score = 35.1 bits (77), Expect = 1.8
Identities = 23/72 (31%), Positives = 32/72 (44%)
Frame = -1
Query: 495 DDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEK 316
DDS Y E +++W D P+Q LY K Y EKA K + V+ + E
Sbjct: 305 DDSQIYAVGEMLEEWEPDTQPVQPELLYPLIKRYISRFPEKA-DKLLKKFVISLLNTHEL 363
Query: 315 KKKPNWKEMLED 280
NW + L+D
Sbjct: 364 PYIQNWLKPLKD 375
>UniRef50_A6DI60 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Lentisphaera araneosa HTCC2155|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Lentisphaera araneosa HTCC2155
Length = 359
Score = 35.1 bits (77), Expect = 1.8
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Frame = -1
Query: 630 TLRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKW 451
T+R + DT+ + + A D A +KP L++ +AY V + S+EE KW
Sbjct: 198 TIRYNDDDTVIIAGGLNWAYDLRDAKDKPFLLDNLAYAVHPYPQKSKDDKNSSMEE--KW 255
Query: 450 TKDESPL-QKFKLYLEHKGYWDAETEKA 370
K + QK+ L G+ + + A
Sbjct: 256 DKMWGFMSQKYPLIATEFGFMSEDDKGA 283
>UniRef50_Q9P1H6 Cluster: PRO1410; n=1; Homo sapiens|Rep: PRO1410 -
Homo sapiens (Human)
Length = 78
Score = 35.1 bits (77), Expect = 1.8
Identities = 20/53 (37%), Positives = 27/53 (50%)
Frame = +1
Query: 256 PGWHFIVDIF*HLFPVWFLFLFRFLHGSNHCIPCFLTPGLLSLRVPVTFMFEI 414
P H +V I H FP WF+F F S+ C+ C + L SL +P F F +
Sbjct: 21 PIMHMLVLIVTHRFPTWFIFHSHFC--SSDCVIC-IDLSLSSLILPSAFKFAV 70
>UniRef50_Q89YV4 Cluster: DNA modification methylase; n=1;
Bacteroides thetaiotaomicron|Rep: DNA modification
methylase - Bacteroides thetaiotaomicron
Length = 991
Score = 34.7 bits (76), Expect = 2.4
Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Frame = -1
Query: 510 HHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTM 331
H + D R + I+ + K F +L+ KG+ K W + RD ++
Sbjct: 220 HTGMAADKIRDREEKPIRDYVKKLLGRIVFLHFLQKKGWLGVPASKEWGEGDRDFMLNIF 279
Query: 330 QEAEKKKKPNW-KEMLEDVYYE 268
+ A +++K N+ ++LED++ E
Sbjct: 280 KNANERQKENFLDDILEDLFTE 301
>UniRef50_A0EER6 Cluster: Chromosome undetermined scaffold_92, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_92,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 527
Score = 34.7 bits (76), Expect = 2.4
Identities = 17/66 (25%), Positives = 37/66 (56%)
Frame = -1
Query: 378 EKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHY 199
+ WS+E V R + + K++P+ KE+L+D +++ + ++ ++Q KK E Y
Sbjct: 229 QSKWSREFNQFVKRCLT-LDPKERPSTKELLQDPFFQKYCKSREYIQQFMLKCKKQIESY 287
Query: 198 PLNQHE 181
L++ +
Sbjct: 288 KLSKQK 293
>UniRef50_UPI0000F20063 Cluster: PREDICTED: similar to LOC560949
protein; n=2; Danio rerio|Rep: PREDICTED: similar to
LOC560949 protein - Danio rerio
Length = 583
Score = 34.3 bits (75), Expect = 3.1
Identities = 17/60 (28%), Positives = 35/60 (58%)
Frame = -1
Query: 384 ETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPE 205
E EK K+ + + MQ+ +K+K +++ E++ E RLQK++++ +E +K+ E
Sbjct: 423 EAEKEQMKKETERKRQEMQDELRKRKEEFEKEEEEIKKEKDERLQKKLQKKQEEQQKHFE 482
>UniRef50_UPI0000E49DA7 Cluster: PREDICTED: similar to Wu:fc43a05;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Wu:fc43a05 - Strongylocentrotus purpuratus
Length = 127
Score = 34.3 bits (75), Expect = 3.1
Identities = 16/57 (28%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Frame = -1
Query: 366 SKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEM---PPRLQKQMKQMEEHLKKYPE 205
SKE + ++T+ E KK++ NW LE++ E + ++K++++H K E
Sbjct: 64 SKEEKHMEIKTLDEQRKKREENWSYFLEELSKERDREDVQHANEIKEIDDHFAKLEE 120
>UniRef50_UPI0000D55AB7 Cluster: PREDICTED: similar to CG7719-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7719-PA - Tribolium castaneum
Length = 518
Score = 34.3 bits (75), Expect = 3.1
Identities = 19/54 (35%), Positives = 30/54 (55%)
Frame = -1
Query: 444 DESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLE 283
DE+P Q FK L+H W + E A SKE D + T+ + +K+P E+++
Sbjct: 419 DETPQQVFKNILDHNIEWPTDDE-ALSKEVVD-AIETLLTPDPEKRPQATEVMK 470
>UniRef50_UPI00004983CC Cluster: chromosome partition protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: chromosome
partition protein - Entamoeba histolytica HM-1:IMSS
Length = 605
Score = 34.3 bits (75), Expect = 3.1
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Frame = -1
Query: 468 EEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEM 289
EE++K + + L++ + + K +A E SKE + + +E +KK KEM
Sbjct: 144 EELKKTKQRNNELER-SIAMSEKKKQEAIKESGISKEKEEIATKKTEEVQKKIDEIEKEM 202
Query: 288 LEDVYYEMPPRLQKQMKQME-EHLKKYPEHY 199
+ + + +LQ MKQ E +++K+ E Y
Sbjct: 203 NKIITEKETMKLQIDMKQNEVKYVKELNETY 233
>UniRef50_UPI00001626D4 Cluster: unknown protein; n=1; Arabidopsis
thaliana|Rep: unknown protein - Arabidopsis thaliana
Length = 435
Score = 34.3 bits (75), Expect = 3.1
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 1/116 (0%)
Frame = -1
Query: 558 ANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYW-DAE 382
ANN + +Y GH S + RS +I+ WT D S + F+ + W D E
Sbjct: 11 ANNSKMSFGQGSY--GHSSWGRSCNCGRSTTKIKSWTDDNSGRRFFRCDVHGFVSWSDVE 68
Query: 381 TEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
+ W K ++ EA + K KE L + + +++ K++EE KK
Sbjct: 69 KQCTWQK-------LSLLEARDELKA-LKESLRTPINQQAIKEEEETKKLEEETKK 116
>UniRef50_Q5M3M3 Cluster: Type II restriction-modification system
restriction subunit; n=5; Streptococcaceae|Rep: Type II
restriction-modification system restriction subunit -
Streptococcus thermophilus (strain ATCC BAA-250 / LMG
18311)
Length = 1470
Score = 34.3 bits (75), Expect = 3.1
Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Frame = -1
Query: 651 GPALGLHTLRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDS----- 487
G LH + D TD+ V++ + D L AM+ + +DD+
Sbjct: 993 GATPNLHWVETDVTDS--VYHPETKIIDINAKTGLYPLHAAMSLYYQYVQNNDDNRFDAE 1050
Query: 486 SAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKK 307
S YR + E + ++P+ K +GY +T A+ + DT+ +++E +K+ +
Sbjct: 1051 SVYRGILENNIYAIAKTPMAKTITERTLRGYKKYKTNVAYIENFSDTLKSSIEEGKKQVE 1110
Query: 306 PNWKEMLEDVYYEMPP 259
+ ++ DV PP
Sbjct: 1111 EAFGKVKFDVVIGNPP 1126
>UniRef50_Q54BL5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1353
Score = 34.3 bits (75), Expect = 3.1
Identities = 26/109 (23%), Positives = 55/109 (50%)
Frame = -1
Query: 468 EEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEM 289
EEI++ TK+ES K ++ E K + E+ +E ++ + ++E + K E+
Sbjct: 650 EEIKQETKEES---KDEISEEEK---EVTMEEEIKEEIKEEIKEEIKEEIDEVKEEIDEV 703
Query: 288 LEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHESD*ITTADIHIVK 142
E++ E+ ++++K+ ++ K PE + E+D I + I+K
Sbjct: 704 KEEIKEEIKEEFKEEIKEGQKIDNKIPEFTFVRSEENDDILMGEEEIIK 752
>UniRef50_Q28WZ4 Cluster: GA15715-PA; n=1; Drosophila
pseudoobscura|Rep: GA15715-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 389
Score = 34.3 bits (75), Expect = 3.1
Identities = 22/75 (29%), Positives = 34/75 (45%)
Frame = -1
Query: 399 GYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHL 220
GY AE S+ + T + + K+ +EM ++VY E P Q ++ EE L
Sbjct: 81 GYSSAEPISGLSRTSSMTNA-SKGRVKSKRNELLEEMRDEVYLENPLYFQGVRQEREEEL 139
Query: 219 KKYPEHYPLNQHESD 175
K +P + HE D
Sbjct: 140 KVFPNVERITHHEVD 154
>UniRef50_A2DCE1 Cluster: Putative uncharacterized protein; n=2;
Eukaryota|Rep: Putative uncharacterized protein -
Trichomonas vaginalis G3
Length = 1433
Score = 34.3 bits (75), Expect = 3.1
Identities = 25/85 (29%), Positives = 40/85 (47%)
Frame = -1
Query: 477 RSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNW 298
R +E +K K+E LQK + E K + E +K E + + ++ E++KK
Sbjct: 968 RQRKEEEKQKKEEEKLQKEREAEEEKKRQELEQKKKLEDEEKKKLEEQKRKEEEQKK--- 1024
Query: 297 KEMLEDVYYEMPPRLQKQMKQMEEH 223
KE+ E +LQ Q K+ E H
Sbjct: 1025 KEIKSQKEKEEKEKLQAQKKEEETH 1049
>UniRef50_A2QWE0 Cluster: Putative uncharacterized protein; n=5;
Eurotiomycetidae|Rep: Putative uncharacterized protein -
Aspergillus niger
Length = 515
Score = 34.3 bits (75), Expect = 3.1
Identities = 23/96 (23%), Positives = 42/96 (43%)
Frame = -1
Query: 579 RARDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHK 400
RA +F V N+K ++ Y D + YR E ++ W K + KL L+
Sbjct: 409 RAHNFAVKNSKRPFLDIKTYH------QDVAKPYRRAENLRFWVKAAELRWETKLELDVM 462
Query: 399 GYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKE 292
G +E+AW K+ ++ + ++ +W+E
Sbjct: 463 GIVHGNSEEAW-KQFDQALLAWCKVVREELVRDWRE 497
>UniRef50_Q8XHG9 Cluster: Putative uncharacterized protein CPE2516;
n=3; Clostridium perfringens|Rep: Putative
uncharacterized protein CPE2516 - Clostridium
perfringens
Length = 540
Score = 33.9 bits (74), Expect = 4.1
Identities = 25/98 (25%), Positives = 43/98 (43%)
Frame = -1
Query: 495 DDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEK 316
+D Y ++ K KD+ K+K YL+ K D + K +KE +K
Sbjct: 171 EDKEKYNDDKDYYKEKKDKDEKDKYKEYLKEK---DKDYLKEENKEKECKKEYCKDTEDK 227
Query: 315 KKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEH 202
+ K + KE L++ Y E + + K+ +H K +H
Sbjct: 228 EDKDDCKEHLKEEYKEKKDDCRGKDKEECKHHDKEEKH 265
>UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily
protein; n=2; Mycobacterium avium|Rep: Dehydrogenase E1
component superfamily protein - Mycobacterium avium
(strain 104)
Length = 297
Score = 33.9 bits (74), Expect = 4.1
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = -1
Query: 621 VDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGH 508
VDG D +AV ++V +A A + P L+EA+ YR H
Sbjct: 196 VDGRDVVAVGDSVGQAVRHASAGDGPSLVEAITYRTNH 233
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 33.9 bits (74), Expect = 4.1
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
+ L +NG AI+T T + + ++G G+ + VDG + V V R V
Sbjct: 304 LFLVIDNGRAINTFTKDVAANQEVFNQGKHYGVPGVLVDGQNVQDVLK-VGRTVINHVRT 362
Query: 552 NKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDE-SPLQKFK 418
P +++ +R HS +D R+ ++ ++W + E P++ F+
Sbjct: 363 KGPAILQVHTFRFNGHSPADPEHE-RNRKDEKRWARAECDPIKIFE 407
>UniRef50_Q871C9 Cluster: Related to heat shock protein dnaJ; n=1;
Neurospora crassa|Rep: Related to heat shock protein
dnaJ - Neurospora crassa
Length = 292
Score = 33.9 bits (74), Expect = 4.1
Identities = 24/67 (35%), Positives = 31/67 (46%)
Frame = -1
Query: 507 HSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQ 328
H TS S YR ++E D QK+ LYL KG + EK +EA+ T V
Sbjct: 182 HFTS--SQRYRDLKEAHDMLIDAEDRQKYDLYLAKKGVPEM-VEKFKVREAKKTSVEKKM 238
Query: 327 EAEKKKK 307
E + KK
Sbjct: 239 EKQTDKK 245
>UniRef50_A5DLJ8 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1107
Score = 33.9 bits (74), Expect = 4.1
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Frame = -1
Query: 477 RSVEEIQKWTKDESPLQKFKLYLEHKGYWD-AETEKAWSKEARDTVVRTMQEAEKKKKP- 304
R EE ++ ++E L++ +L E K + A +K K R +R +EAEKKK+
Sbjct: 636 RRKEEEERAREEELRLKQEELRAEQKRRKEEARQKKEEEKRKRIEELRLKKEAEKKKQEE 695
Query: 303 ---NWKEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
+E+ E E+ + +++M + +E LKK
Sbjct: 696 KERKERELKEKKERELKEKEEREMMEKKEQLKK 728
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 33.9 bits (74), Expect = 4.1
Identities = 18/46 (39%), Positives = 26/46 (56%)
Frame = -1
Query: 621 VDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSS 484
V+G D AV A K A +F + +KPV+I+ YR H+ D+ S
Sbjct: 477 VNGDDPEAVVFAAKVATEFRMTFHKPVVIDMFCYRRFGHNEGDEPS 522
>UniRef50_UPI00006CD2BD Cluster: Viral A-type inclusion protein repeat
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Viral A-type inclusion protein repeat
containing protein - Tetrahymena thermophila SB210
Length = 1285
Score = 33.5 bits (73), Expect = 5.5
Identities = 22/104 (21%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Frame = -1
Query: 510 HHSTSDDSSA--YRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVR 337
H T D R ++E++ + +++ ++K K LE+ + K ++ D +
Sbjct: 712 HRKTIDSMKKEHQRQLDELRNYYEEQ--IRKLKAQLENNARGVIDDLKQKHQQELDRLKN 769
Query: 336 TMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPE 205
++ KK W+ L+ E +++ M QME+ KY +
Sbjct: 770 MYEDQIKKLNQEWEIKLQKTIDEYERKIKNLMNQMEQERLKYQQ 813
>UniRef50_Q2W161 Cluster: Putative uncharacterized protein; n=2;
Magnetospirillum|Rep: Putative uncharacterized protein -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 499
Score = 33.5 bits (73), Expect = 5.5
Identities = 15/51 (29%), Positives = 29/51 (56%)
Frame = -1
Query: 330 QEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHES 178
+E E ++K W+ +D+ YE+PP L +K+++ + + P P + ES
Sbjct: 154 KEDEAERKARWEARHKDIEYELPPNLAHLLKRLDYVVPELPP--PAGKFES 202
>UniRef50_O51650 Cluster: Putative uncharacterized protein BB0707;
n=3; Borrelia burgdorferi group|Rep: Putative
uncharacterized protein BB0707 - Borrelia burgdorferi
(Lyme disease spirochete)
Length = 608
Score = 33.5 bits (73), Expect = 5.5
Identities = 25/92 (27%), Positives = 41/92 (44%)
Frame = -1
Query: 348 TVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHESD*I 169
T++ +Q K N ++ L++ YE+ + +K +EE LK Y +N I
Sbjct: 169 TILEIIQSKVLNSKNNLEDFLDEGEYELFLKKEKTQNDLEESLKVKINEY-INS-----I 222
Query: 168 TTADIHIVKIIFMVYCLFGVFILFTV*IFFSF 73
++ IV +F Y +F F FFSF
Sbjct: 223 PSSTYKIVSDMFEFYYVFNSLAFFPYKSFFSF 254
>UniRef50_Q9XH27 Cluster: F10A2.9 protein; n=1; Arabidopsis
thaliana|Rep: F10A2.9 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 684
Score = 33.5 bits (73), Expect = 5.5
Identities = 15/58 (25%), Positives = 29/58 (50%)
Frame = -1
Query: 402 KGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQME 229
KGYWD +T + K +D + KK+K + E ++ + + + +K+ K+ E
Sbjct: 37 KGYWDVKTSEKKKKLVKDKEAEVSESPAKKQKVSQSEDVDSLEKDAEKKKKKKNKKKE 94
>UniRef50_Q0DWE7 Cluster: Os02g0818500 protein; n=2; Oryza sativa
(japonica cultivar-group)|Rep: Os02g0818500 protein -
Oryza sativa subsp. japonica (Rice)
Length = 282
Score = 33.5 bits (73), Expect = 5.5
Identities = 27/120 (22%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Frame = -1
Query: 564 TVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDA 385
T++ K VL A+ Y + +++ + +++ + DE + + + H+ ++
Sbjct: 5 TLSVGKSVLNGALGY--AKSAFAEEVALQLGIQKDHTFVADELEMMRSFMMEAHEEQDNS 62
Query: 384 ETEKAWSKEARDT---VVRTMQE-AEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLK 217
+ K W K+ RDT V ++Q+ A KKP+W + R+ KQMK++ ++
Sbjct: 63 KVVKTWVKQVRDTAYDVEDSLQDFAVHLKKPSWWRFPRTLLERR--RVAKQMKELRNKVE 120
>UniRef50_UPI00004986FF Cluster: conserved hypothetical protein;
n=9; Entamoeba histolytica HM-1:IMSS|Rep: conserved
hypothetical protein - Entamoeba histolytica HM-1:IMSS
Length = 406
Score = 33.1 bits (72), Expect = 7.2
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
Frame = -1
Query: 354 RDTVVRTMQEAEK------KKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPL 193
RD ++R QE +K KKK W+ D Y+ ++++K+ EE KK + +
Sbjct: 129 RDKILRKPQERDKITSEFNKKKEEWETYYSD-YFSRKKIKEEEVKKQEEERKKQEQERKI 187
Query: 192 NQHE 181
+H+
Sbjct: 188 QEHD 191
>UniRef50_Q914N0 Cluster: ORF1; n=8; Torque teno virus|Rep: ORF1 -
Torque teno virus
Length = 719
Score = 33.1 bits (72), Expect = 7.2
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = -2
Query: 470 WRRYKSGPKMRVLCRSSSF--ISNIKVTGTRRLRRPGVRKQGIQWLEPCRKRKRKRNQTG 297
WRR PK R R ++ + R RRP VR++ QW P R R R+R +
Sbjct: 4 WRRRFWRPKRRWRWRRRRRRPLARRRRRPARLARRPRVRRRRFQWGRPRRYRPRRRRRRR 63
Query: 296 KR 291
KR
Sbjct: 64 KR 65
>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 665
Score = 33.1 bits (72), Expect = 7.2
Identities = 26/96 (27%), Positives = 46/96 (47%)
Frame = -1
Query: 546 PVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAW 367
P ++ R+ HS SD YR+ +E++ + P++ + YL+ KG A TE+A
Sbjct: 240 PCILVCRMDRLDSHSNSDSHKLYRTPDELEVL---QDPIENYVAYLKEKG---AITEQA- 292
Query: 366 SKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPP 259
+ E +++ K + E+ E VY+E P
Sbjct: 293 -----------LAEQKERIKADVAEIFERVYHEEEP 317
>UniRef50_Q2GD66 Cluster: Transketolase, insertion; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Transketolase,
insertion - Neorickettsia sennetsu (strain Miyayama)
Length = 752
Score = 33.1 bits (72), Expect = 7.2
Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Frame = -1
Query: 732 IMLXRNNGYAISTPTSEQYRGDGIASRGPALGLHTLRVDGTDTLAVHNAVKRARDFTVAN 553
I+ +NG +I TS D R + G ++DG D A+ NA+ AR ++
Sbjct: 173 ILFFDDNGISIDGSTS-LCLSDNNLKRFESYGWDVQQIDGHDFAAIENAIANAR----SS 227
Query: 552 NKPVLIEA---MAYRVGHHSTSDDSSAYRSVEEIQKWTKD-ESPLQKFKL 415
++P LI A + + TS S + EE+ + K E PL++F +
Sbjct: 228 DRPSLIAAKTVIGKSMPKEGTSKTHSGGLTREEVIAFRKRLEYPLEEFSI 277
>UniRef50_Q05WA5 Cluster: Putative dape protein; n=1; Synechococcus
sp. RS9916|Rep: Putative dape protein - Synechococcus
sp. RS9916
Length = 136
Score = 33.1 bits (72), Expect = 7.2
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = -1
Query: 561 VANNKPVLIEAMAYRVGHHSTSD-DSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYW 391
VANN ++++ YR+ H +S+ R V + + +K E L+ ++ L H G W
Sbjct: 32 VANNLNTVLQSNTYRLAHEDQELLNSNEMRGVRMLLEISKPEMVLEAEQILLHHPGIW 89
>UniRef50_A1ZRD4 Cluster: Tetratricopeptide repeat domain protein;
n=1; Microscilla marina ATCC 23134|Rep:
Tetratricopeptide repeat domain protein - Microscilla
marina ATCC 23134
Length = 449
Score = 33.1 bits (72), Expect = 7.2
Identities = 15/57 (26%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = -1
Query: 360 EARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPR---LQKQMKQMEEHLKKYPEHY 199
E +R ++E EKK++ +K+ML++ + + Q+++K+ ++ +KK E Y
Sbjct: 359 EQEQEYLRKLREKEKKRQEAYKKMLQEQQERVKKQQEEYQRKLKEQQDRIKKQQEEY 415
>UniRef50_A0HIT5 Cluster: Phage-related protein predicted
endonuclease-like; n=1; Comamonas testosteroni KF-1|Rep:
Phage-related protein predicted endonuclease-like -
Comamonas testosteroni KF-1
Length = 637
Score = 33.1 bits (72), Expect = 7.2
Identities = 20/78 (25%), Positives = 31/78 (39%)
Frame = -1
Query: 528 MAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARD 349
+ YRV + S + R + KWT + PL+ + E A+ W + +D
Sbjct: 134 LQYRVQMEQQAMVSGSERILFMASKWTSEGLPLEALHCWYEPDAELRAQIIAGWEQIEKD 193
Query: 348 TVVRTMQEAEKKKKPNWK 295
Q AE K +P K
Sbjct: 194 VAAYQPQAAEPKPQPEAK 211
>UniRef50_Q61F95 Cluster: Putative uncharacterized protein CBG11726;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG11726 - Caenorhabditis
briggsae
Length = 852
Score = 33.1 bits (72), Expect = 7.2
Identities = 23/89 (25%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = -1
Query: 480 YRSVEEIQKWT--KDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKK 307
+R +E++ WT +D QK K + K +A K + EA+ + ++ EK+K
Sbjct: 51 FRRIEKVASWTHVRDIRRKQKEKRLEQEKKEKEA---KKLNLEAKKEAEKLKKQDEKRKN 107
Query: 306 PNWKEMLEDVYYEMPPRLQKQMKQMEEHL 220
K++ +D E ++++ K +EE+L
Sbjct: 108 LEEKQLKDDEKLEYLEKMKEDEKLLEENL 136
>UniRef50_Q23QN9 Cluster: Dynein heavy chain family protein; n=4;
Eukaryota|Rep: Dynein heavy chain family protein -
Tetrahymena thermophila SB210
Length = 4329
Score = 33.1 bits (72), Expect = 7.2
Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Frame = -1
Query: 297 KEMLEDVYYEMPPRLQKQMKQM-EEHLKKYPEHYPLNQHESD*ITTADIHIVKIIFMVYC 121
K L D+Y E+ R +++K++ + L ++ + YP N+ TA HI+KI+ ++
Sbjct: 2586 KRRLADIYCELSDR--EELKRVCYDQLAQFNDSYPQNKMNLVLFMTAIQHIIKIVRVITT 2643
Query: 120 LFGVFILFTV 91
FG +L V
Sbjct: 2644 SFGHCLLVGV 2653
>UniRef50_A5K5E5 Cluster: Tryptophan-rich antigen; n=1; Plasmodium
vivax|Rep: Tryptophan-rich antigen - Plasmodium vivax
Length = 316
Score = 33.1 bits (72), Expect = 7.2
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Frame = -1
Query: 462 IQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLE 283
+ KW + ++ K + +L + W E + W+ R T + +QEAEK WKE +
Sbjct: 195 LDKWVQWKN--DKIRSWLSSE--WKTEEDYYWANVERATTAKWLQEAEKMHWLKWKERIN 250
Query: 282 DVYYEMPPRLQ-KQMKQMEEHLKKYPE 205
+ +Q K+ + KK+P+
Sbjct: 251 RESEQWVNWVQMKESVYINVEWKKWPK 277
>UniRef50_A0EE63 Cluster: Chromosome undetermined scaffold_91, whole
genome shotgun sequence; n=7; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_91, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 4298
Score = 33.1 bits (72), Expect = 7.2
Identities = 21/69 (30%), Positives = 33/69 (47%)
Frame = -1
Query: 297 KEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHESD*ITTADIHIVKIIFMVYCL 118
K + D+Y E+ R + K +E L +Y Y N+ E A H++KI+ +V
Sbjct: 2561 KRPMTDIYCELTDR-ETLKKVCQEQLNEYNSQYTSNRMELVLFMNAIQHVLKIVRVVNTT 2619
Query: 117 FGVFILFTV 91
FG +L V
Sbjct: 2620 FGHALLVGV 2628
>UniRef50_A0CSW1 Cluster: Chromosome undetermined scaffold_26, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_26,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 569
Score = 33.1 bits (72), Expect = 7.2
Identities = 18/77 (23%), Positives = 42/77 (54%)
Frame = -1
Query: 441 ESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMP 262
E ++F+ YLE A + K+ + +++T Q+ E++K+ +++ ++ +
Sbjct: 336 EQKRREFEEYLEKVRLEKARQAEDKQKQI-NKIMQTNQQKEEEKRQQYEQKQQEYQKKKE 394
Query: 261 PRLQKQMKQMEEHLKKY 211
++Q +QME+ +KKY
Sbjct: 395 VMNEQQRQQMEDKMKKY 411
>UniRef50_A5DJ03 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 412
Score = 33.1 bits (72), Expect = 7.2
Identities = 26/112 (23%), Positives = 46/112 (41%)
Frame = -1
Query: 510 HHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTM 331
H TSD S S E ++ ES QK+ L GY+ ++ S D VV+++
Sbjct: 244 HSKTSDVESEPESEPESDSKSEPESATQKYNLPQLATGYFSGGSDDDGSDIDEDQVVKSV 303
Query: 330 QEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHESD 175
E++K + + ++ + + K +K+ L E L E +
Sbjct: 304 --TERRKNRRGQRARQKIWAQKYGKEAKHIKEERTRLASEREQRQLEYEERE 353
>UniRef50_Q8DWE0 Cluster: DNA polymerase III polC-type; n=60;
Lactobacillales|Rep: DNA polymerase III polC-type -
Streptococcus mutans
Length = 1465
Score = 33.1 bits (72), Expect = 7.2
Identities = 16/49 (32%), Positives = 24/49 (48%)
Frame = -1
Query: 537 IEAMAYRVGHHSTSDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYW 391
+E R G H + + Y S +QKW KD+ L+K+ + KG W
Sbjct: 251 VERKTTRTGRHIINFKMTDYTSSFPMQKWAKDDEELKKYDMI--SKGAW 297
>UniRef50_UPI00015B5E53 Cluster: PREDICTED: similar to GA17752-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA17752-PA - Nasonia vitripennis
Length = 1304
Score = 32.7 bits (71), Expect = 9.5
Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 3/39 (7%)
Frame = -1
Query: 309 KPNWK--EMLEDVYYEMPPRL-QKQMKQMEEHLKKYPEH 202
KPN K + L+D+ Y++ P L K+M++ E K+PEH
Sbjct: 65 KPNIKADKALQDIVYKLVPGLYHKEMRKRREFYSKHPEH 103
>UniRef50_UPI0000F1F901 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1018
Score = 32.7 bits (71), Expect = 9.5
Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 5/107 (4%)
Frame = -1
Query: 498 SDDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGY-WDAETEK----AWSKEARDTVVRT 334
S +YR+ ++ + + P L + + WD E E+ W KE +
Sbjct: 690 SSRPESYRTKADMAEKAHENVPPSVLNLVNRGEHFSWDPEEERNRQERWQKEQERMLQEK 749
Query: 333 MQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPL 193
+ ++K K W++ ++V E +++ K +EE + H P+
Sbjct: 750 YRREQEKLKQEWEQAQKEVEEEERRYHEEEQKILEETVTPLTPHSPI 796
>UniRef50_UPI00005199E9 Cluster: PREDICTED: similar to F46F6.4; n=1;
Apis mellifera|Rep: PREDICTED: similar to F46F6.4 - Apis
mellifera
Length = 303
Score = 32.7 bits (71), Expect = 9.5
Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Frame = -1
Query: 357 ARDTVVRTMQEAEKKKK--PNWKEMLEDVYYEMPP---RLQKQMKQMEEHLKKYPEHY-- 199
AR TV++ +++AEK K W E ++ ++ P L K M +++ L+++P
Sbjct: 186 ARQTVIKRIEDAEKNGKSIEKWIEDIDQLHRSKHPPAVHLTKPMPEIDSLLQQWPPEVEE 245
Query: 198 PLNQHESD*ITTADIHIVKIIFMVYCLFGV 109
LN+ E D T D + +++ +V L +
Sbjct: 246 KLNEAELD-FTELDCELPELVDIVCNLLDI 274
>UniRef50_UPI0000499F7A Cluster: Rho GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Rho GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 894
Score = 32.7 bits (71), Expect = 9.5
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = -1
Query: 468 EEIQKWTKDESPLQKFKLY-LEHKGYWDA-ETEKAWSKEARDT----VVRTMQEAEKKKK 307
EE +K E ++K +L +E + D E E+ +K R+ + R M E EKK+K
Sbjct: 668 EEAEKRRLQEEEMEKERLEAIERQKEIDRLEEEETKAKIEREKKRAEIEREMAEIEKKEK 727
Query: 306 PNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPE 205
E + E R++ ++K+ EE LKK E
Sbjct: 728 QRQLEEEKKRKEEELKRIENEIKRKEEELKKQEE 761
>UniRef50_Q8CDD5 Cluster: Adult male testis cDNA, RIKEN full-length
enriched library, clone:4933423P14 product:hypothetical
protein, full insert sequence; n=5; Murinae|Rep: Adult
male testis cDNA, RIKEN full-length enriched library,
clone:4933423P14 product:hypothetical protein, full
insert sequence - Mus musculus (Mouse)
Length = 469
Score = 32.7 bits (71), Expect = 9.5
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Frame = -1
Query: 495 DDSSAYRSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQE--- 325
+D + S E+I + K ++ HKG+W E KA ++E + + + QE
Sbjct: 322 EDLNLLESGEQITRKLKKKAKALDAMAKQAHKGFW--EGIKAQNRELKTQLWQLNQEFCK 379
Query: 324 ----AEK--KKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQ 187
EK ++K WKE + Y E R +++++Q E ++ H+P Q
Sbjct: 380 LEAGKEKLERRKQRWKE--QQWYLEALARGRERLQQQEYRRQQQENHHPRPQ 429
>UniRef50_Q1UAK9 Cluster: Putative uncharacterized protein; n=1;
Lactobacillus reuteri 100-23|Rep: Putative
uncharacterized protein - Lactobacillus reuteri 100-23
Length = 139
Score = 32.7 bits (71), Expect = 9.5
Identities = 17/84 (20%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = -1
Query: 630 TLRVDGTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDSSAYRSVEEIQKW 451
TL++ +L ++A+ DF N P + AM + ++ ++ + + +W
Sbjct: 44 TLKIIYRVSLERNDAINTLNDFIAGRNLPWIESAMHFLEMYYDQKENGMTHEIEIAMCEW 103
Query: 450 TKDES-PLQKFKLYLEHKGYWDAE 382
+ ++ P+Q +L H W E
Sbjct: 104 ARSKNVPIQAVRLITRHNWEWSVE 127
>UniRef50_A5VEW4 Cluster: Polysaccharide deacetylase; n=1;
Sphingomonas wittichii RW1|Rep: Polysaccharide
deacetylase - Sphingomonas wittichii RW1
Length = 321
Score = 32.7 bits (71), Expect = 9.5
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = -1
Query: 615 GTDTLAVHNAVKRARDFTVANNKPVLIEAMAYRVGHHSTSDDS 487
G D A H ++RARD + P + +A+R G H+ DDS
Sbjct: 115 GHDRGAQHELIRRARDLLMEAGAP---DPIAFRAGDHAADDDS 154
>UniRef50_A2D7K4 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 994
Score = 32.7 bits (71), Expect = 9.5
Identities = 33/99 (33%), Positives = 46/99 (46%)
Frame = -1
Query: 477 RSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNW 298
+ + EI++ K ES QK K EH + ET K +K + + QE E KK NW
Sbjct: 568 KKINEIKQ--KIESR-QKAKADAEH--FLQEETAKRQAK-----IEQLRQELETLKK-NW 616
Query: 297 KEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQHE 181
E E + E +L+K K+ EE +K E L E
Sbjct: 617 AEEKEKINKEYSEKLEKLKKENEEAERKAEEQRRLKDAE 655
>UniRef50_A0C3D0 Cluster: Chromosome undetermined scaffold_147,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_147,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 822
Score = 32.7 bits (71), Expect = 9.5
Identities = 20/82 (24%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Frame = -1
Query: 357 ARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKKYPEHYPLNQH-E 181
++ + + +Q+ EK++K +E D Y++ R++K+ + + L++Y + NQ+ E
Sbjct: 17 SKQELTQLLQKLEKEQKD--EETQSDQYFDQLARVEKEYETLVHILEEYGKKIANNQNGE 74
Query: 180 SD*ITTADIHIVKIIFMVYCLF 115
+D AD I K + L+
Sbjct: 75 TDQAQDADFRIEKAVIETLNLY 96
>UniRef50_A0BVV4 Cluster: Chromosome undetermined scaffold_130, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_130, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1339
Score = 32.7 bits (71), Expect = 9.5
Identities = 25/88 (28%), Positives = 47/88 (53%)
Frame = -1
Query: 477 RSVEEIQKWTKDESPLQKFKLYLEHKGYWDAETEKAWSKEARDTVVRTMQEAEKKKKPNW 298
R ++E+QK K+E+ ++F +L D + +K S + + + EKKK +
Sbjct: 974 RRLDELQKQEKEEAIKKRFAAFL-----LDPQYDKLLSNNE----LMQLTDDEKKK---Y 1021
Query: 297 KEMLEDVYYEMPPRLQKQMKQMEEHLKK 214
+ LED+ ++P R +K ++Q + LKK
Sbjct: 1022 QAALEDLLLKVPQRQKKSIQQQIDLLKK 1049
>UniRef50_A5YS53 Cluster: Helicase, C-terminal; n=1; uncultured
haloarchaeon|Rep: Helicase, C-terminal - uncultured
haloarchaeon
Length = 1121
Score = 32.7 bits (71), Expect = 9.5
Identities = 16/67 (23%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Frame = -1
Query: 384 ETEKAWSKEARDTVVRTMQEAEKKKKPNWKEMLEDVYYEMPPRLQKQMKQMEEHLKK-YP 208
+TE+A+ + R+ + + A W+E + + + P ++K +Q+ +HL+K YP
Sbjct: 963 KTERAFPDDMRNKIYDAWETARSDIHDQWQEQTDPM--NVQPDIRKLFRQVGDHLRKYYP 1020
Query: 207 EHYPLNQ 187
+ N+
Sbjct: 1021 DDLTQNE 1027
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 673,626,548
Number of Sequences: 1657284
Number of extensions: 12879280
Number of successful extensions: 53937
Number of sequences better than 10.0: 222
Number of HSP's better than 10.0 without gapping: 51081
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 53754
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59265488880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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