Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV11f13f
(615 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxyl... 204 2e-52
S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto... 204 2e-52
S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain ... 204 2e-52
J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto... 204 2e-52
BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto aci... 204 2e-52
BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto aci... 204 2e-52
BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto aci... 204 2e-52
AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein. 204 2e-52
AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto aci... 204 2e-52
M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human branched-... 189 6e-48
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 40 0.009
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 40 0.009
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 40 0.009
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 40 0.009
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 40 0.009
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 40 0.009
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 40 0.009
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 38 0.028
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 35 0.20
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 35 0.20
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 35 0.20
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 35 0.20
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 35 0.20
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 35 0.20
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 35 0.20
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 35 0.20
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 35 0.20
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 35 0.20
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 35 0.20
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 35 0.20
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 35 0.20
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 35 0.26
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 35 0.26
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 33 1.1
CR541928-1|CAG46726.1| 274|Homo sapiens CCS protein. 32 1.4
BC112055-1|AAI12056.1| 274|Homo sapiens copper chaperone for su... 32 1.4
BC105016-1|AAI05017.1| 274|Homo sapiens copper chaperone for su... 32 1.4
AY113179-1|AAM50090.1| 274|Homo sapiens superoxide dismutase co... 32 1.4
AF002210-1|AAC51764.1| 274|Homo sapiens copper chaperone for su... 32 1.4
L23808-1|AAA58658.1| 470|Homo sapiens metalloproteinase protein. 30 5.6
BC112301-1|AAI12302.1| 470|Homo sapiens matrix metalloproteinas... 30 5.6
AY856072-1|AAW29944.1| 470|Homo sapiens matrix metalloproteinas... 30 5.6
>Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxylase
alpha subunit protein.
Length = 445
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 209
>S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto
acid dehydrogenase E1 alpha subunit protein.
Length = 443
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 51 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 110
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 111 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 170
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 171 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 207
>S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain
alpha-keto acid dehydrogenase complex E1 alpha subunit
[human, Genomic, 195 nt, segment 8 of 8]. ).
Length = 387
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 51 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 110
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 111 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 170
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 171 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 207
>J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto
acid dehydrogenase protein.
Length = 444
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 52 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 111
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 112 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 171
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 172 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 208
>BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 209
>BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 209
>BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 209
>AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein.
Length = 479
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 87 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 146
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 147 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 206
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 207 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 243
>AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide variant protein.
Length = 444
Score = 204 bits (498), Expect = 2e-52
Identities = 93/157 (59%), Positives = 115/157 (73%)
Frame = +1
Query: 142 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 321
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 502 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPL 612
+ QCYGN D GKGRQMPVHYG K + VTISSPL
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPL 209
>M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human
branched-chain alpha-keto acid dehydrogenase E1-alpha
subunit (BCKDH) mRNA, partial cds. ).
Length = 378
Score = 189 bits (461), Expect = 6e-48
Identities = 87/134 (64%), Positives = 103/134 (76%)
Frame = +1
Query: 211 IPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKILYESQRQGRISFYMTNY 390
IPIYRVMD GQII+ +E+P+L K ++ +YK+M L+ MD+ILYESQRQGRISFYMTNY
Sbjct: 9 IPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNY 68
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
GEEG H+GSA+AL DLVF QYRE GV +YR + + QCYGN D GKGRQMPVHY
Sbjct: 69 GEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHY 128
Query: 571 GSKHHNMVTISSPL 612
G K + VTISSPL
Sbjct: 129 GCKERHFVTISSPL 142
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 39.5 bits (88), Expect = 0.009
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG++V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 172
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 39.5 bits (88), Expect = 0.009
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG++V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 172
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 39.5 bits (88), Expect = 0.009
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG++V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 172
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 39.5 bits (88), Expect = 0.009
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG++V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 172
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 39.5 bits (88), Expect = 0.009
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG++V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 172
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 39.5 bits (88), Expect = 0.009
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 73 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 132
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG++V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 133 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 191
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 39.5 bits (88), Expect = 0.009
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG++V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 172
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 37.9 bits (84), Expect = 0.028
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
Frame = +1
Query: 274 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 450
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 451 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKH----HNMVTISSPLG 615
+ YR GV RG +V ++ + G KG+ +H +K+ + +V PLG
Sbjct: 114 TSYRAHGVCYTRGPSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLG 172
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 120 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 179
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 180 YAKNFYGGNGIVGAQVPLG 198
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 134 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 193
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 194 YAKNFYGGNGIVGAQVPLG 212
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 35.1 bits (77), Expect = 0.20
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 156 YAKNFYGGNGIVGAQVPLG 174
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 34.7 bits (76), Expect = 0.26
Identities = 17/64 (26%), Positives = 33/64 (51%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 571 GSKH 582
+K+
Sbjct: 156 YAKN 159
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 34.7 bits (76), Expect = 0.26
Identities = 17/64 (26%), Positives = 33/64 (51%)
Frame = +1
Query: 391 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 570
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 134 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 193
Query: 571 GSKH 582
+K+
Sbjct: 194 YAKN 197
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 32.7 bits (71), Expect = 1.1
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Frame = +1
Query: 394 EEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYG 573
+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 104 QEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMY 163
Query: 574 SKH----HNMVTISSPLG 615
+K+ + +V PLG
Sbjct: 164 AKNFYGGNGIVGAQVPLG 181
>CR541928-1|CAG46726.1| 274|Homo sapiens CCS protein.
Length = 274
Score = 32.3 bits (70), Expect = 1.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +3
Query: 381 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 545
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 546 RETDAGP 566
+E+ P
Sbjct: 265 KESAQPP 271
>BC112055-1|AAI12056.1| 274|Homo sapiens copper chaperone for
superoxide dismutase protein.
Length = 274
Score = 32.3 bits (70), Expect = 1.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +3
Query: 381 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 545
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 546 RETDAGP 566
+E+ P
Sbjct: 265 KESAQPP 271
>BC105016-1|AAI05017.1| 274|Homo sapiens copper chaperone for
superoxide dismutase protein.
Length = 274
Score = 32.3 bits (70), Expect = 1.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +3
Query: 381 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 545
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 546 RETDAGP 566
+E+ P
Sbjct: 265 KESAQPP 271
>AY113179-1|AAM50090.1| 274|Homo sapiens superoxide dismutase
copper chaperone protein.
Length = 274
Score = 32.3 bits (70), Expect = 1.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +3
Query: 381 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 545
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 546 RETDAGP 566
+E+ P
Sbjct: 265 KESAQPP 271
>AF002210-1|AAC51764.1| 274|Homo sapiens copper chaperone for
superoxide dismutase protein.
Length = 274
Score = 32.3 bits (70), Expect = 1.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +3
Query: 381 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 545
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 546 RETDAGP 566
+E+ P
Sbjct: 265 KESAQPP 271
>L23808-1|AAA58658.1| 470|Homo sapiens metalloproteinase protein.
Length = 470
Score = 30.3 bits (65), Expect = 5.6
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +1
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 502 EL--VNQCYGNCEDPGKGRQMP 561
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
>BC112301-1|AAI12302.1| 470|Homo sapiens matrix metalloproteinase
12, preproprotein protein.
Length = 470
Score = 30.3 bits (65), Expect = 5.6
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +1
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 502 EL--VNQCYGNCEDPGKGRQMP 561
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
>AY856072-1|AAW29944.1| 470|Homo sapiens matrix metalloproteinase
12 (macrophage elastase) protein.
Length = 470
Score = 30.3 bits (65), Expect = 5.6
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +1
Query: 322 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 501
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 502 EL--VNQCYGNCEDPGKGRQMP 561
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,509,511
Number of Sequences: 237096
Number of extensions: 2018332
Number of successful extensions: 8231
Number of sequences better than 10.0: 42
Number of HSP's better than 10.0 without gapping: 8116
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8231
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6579110070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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