Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV11e24r
(644 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 141 2e-33
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 141 2e-33
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 141 2e-33
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 141 2e-33
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 140 4e-33
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 140 4e-33
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 140 4e-33
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 139 7e-33
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 139 9e-33
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 124 3e-28
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 117 3e-26
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 85 3e-16
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 85 3e-16
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 85 3e-16
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 78 2e-14
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 78 2e-14
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 78 2e-14
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 75 2e-13
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 75 2e-13
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 75 2e-13
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 75 2e-13
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 75 2e-13
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 52 2e-06
U83246-1|AAC15920.1| 537|Homo sapiens copine I protein. 35 0.28
CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein. 35 0.28
BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein. 35 0.28
AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein. 35 0.28
AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein. 35 0.28
AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein. 35 0.28
AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein. 35 0.28
BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein. 33 1.1
BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein. 33 1.1
AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein. 33 1.1
AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein. 33 1.1
BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein. 30 6.1
AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein. 30 6.1
AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related... 30 6.1
AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation ... 30 6.1
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 141 bits (342), Expect = 2e-33
Identities = 70/199 (35%), Positives = 110/199 (55%), Gaps = 1/199 (0%)
Frame = -3
Query: 639 VAEKKCKRRLPVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 460
+A K+ P + T+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 459 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 280
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 279 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 103
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 102 TPRKSAFVYKEILRSRVID 46
P SA Y +I+R+ ++
Sbjct: 448 VPYTSAKEYAKIIRNNGLE 466
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 141 bits (342), Expect = 2e-33
Identities = 70/199 (35%), Positives = 110/199 (55%), Gaps = 1/199 (0%)
Frame = -3
Query: 639 VAEKKCKRRLPVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 460
+A K+ P + T+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 459 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 280
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 279 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 103
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 102 TPRKSAFVYKEILRSRVID 46
P SA Y +I+R+ ++
Sbjct: 448 VPYTSAKEYAKIIRNNGLE 466
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 141 bits (342), Expect = 2e-33
Identities = 70/199 (35%), Positives = 110/199 (55%), Gaps = 1/199 (0%)
Frame = -3
Query: 639 VAEKKCKRRLPVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 460
+A K+ P + T+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 459 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 280
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 279 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 103
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 102 TPRKSAFVYKEILRSRVID 46
P SA Y +I+R+ ++
Sbjct: 448 VPYTSAKEYAKIIRNNGLE 466
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 141 bits (342), Expect = 2e-33
Identities = 70/199 (35%), Positives = 110/199 (55%), Gaps = 1/199 (0%)
Frame = -3
Query: 639 VAEKKCKRRLPVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 460
+A K+ P + T+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 459 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 280
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 279 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 103
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 102 TPRKSAFVYKEILRSRVID 46
P SA Y +I+R+ ++
Sbjct: 448 VPYTSAKEYAKIIRNNGLE 466
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 140 bits (339), Expect = 4e-33
Identities = 68/175 (38%), Positives = 94/175 (53%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYW 406
T+ E+ + G DFFG NHYT L + + D V + WP S S+W
Sbjct: 1664 TESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--DRGVASIADRSWPDSGSFW 1721
Query: 405 LTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLD 226
L ++P L +L++ YNDP Y+TENG S L D RI Y R + L +
Sbjct: 1722 LKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQ 1781
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
+ L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1782 DKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 117 bits (282), Expect = 3e-26
Identities = 69/176 (39%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYW 406
T+EE+ +R +D F +N Y +V + P+ D + P WP +A
Sbjct: 1190 TEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN- 1246
Query: 405 LTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC-- 232
+P L ++++ Y D YITENG N D DRI Y++ + L
Sbjct: 1247 -RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYR 1304
Query: 231 LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1305 LD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 115 bits (277), Expect = 1e-25
Identities = 63/187 (33%), Positives = 106/187 (56%), Gaps = 5/187 (2%)
Frame = -3
Query: 609 PVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPE 430
PV Q T+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 659 PVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHV 716
Query: 429 WPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYY 262
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y+
Sbjct: 717 WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYF 775
Query: 261 RAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSA 85
+ VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA
Sbjct: 776 NQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSA 835
Query: 84 FVYKEIL 64
+ + I+
Sbjct: 836 YFFTSII 842
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 140 bits (339), Expect = 4e-33
Identities = 68/175 (38%), Positives = 94/175 (53%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYW 406
T+ E+ + G DFFG NHYT L + + D V + WP S S+W
Sbjct: 1664 TESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--DRGVASIADRSWPDSGSFW 1721
Query: 405 LTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLD 226
L ++P L +L++ YNDP Y+TENG S L D RI Y R + L +
Sbjct: 1722 LKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQ 1781
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
+ L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1782 DKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 117 bits (282), Expect = 3e-26
Identities = 69/176 (39%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYW 406
T+EE+ +R +D F +N Y +V + P+ D + P WP +A
Sbjct: 1190 TEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN- 1246
Query: 405 LTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC-- 232
+P L ++++ Y D YITENG N D DRI Y++ + L
Sbjct: 1247 -RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYR 1304
Query: 231 LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1305 LD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 115 bits (277), Expect = 1e-25
Identities = 63/187 (33%), Positives = 106/187 (56%), Gaps = 5/187 (2%)
Frame = -3
Query: 609 PVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPE 430
PV Q T+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 659 PVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHV 716
Query: 429 WPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYY 262
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y+
Sbjct: 717 WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYF 775
Query: 261 RAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSA 85
+ VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA
Sbjct: 776 NQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSA 835
Query: 84 FVYKEIL 64
+ + I+
Sbjct: 836 YFFTSII 842
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 140 bits (339), Expect = 4e-33
Identities = 68/175 (38%), Positives = 94/175 (53%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYW 406
T+ E+ + G DFFG NHYT L + + D V + WP S S+W
Sbjct: 1664 TESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--DRGVASIADRSWPDSGSFW 1721
Query: 405 LTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLD 226
L ++P L +L++ YNDP Y+TENG S L D RI Y R + L +
Sbjct: 1722 LKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQ 1781
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
+ L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1782 DKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 117 bits (282), Expect = 3e-26
Identities = 69/176 (39%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYW 406
T+EE+ +R +D F +N Y +V + P+ D + P WP +A
Sbjct: 1190 TEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN- 1246
Query: 405 LTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC-- 232
+P L ++++ Y D YITENG N D DRI Y++ + L
Sbjct: 1247 -RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYR 1304
Query: 231 LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1305 LD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 115 bits (277), Expect = 1e-25
Identities = 63/187 (33%), Positives = 106/187 (56%), Gaps = 5/187 (2%)
Frame = -3
Query: 609 PVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPE 430
PV Q T+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 659 PVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHV 716
Query: 429 WPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYY 262
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y+
Sbjct: 717 WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYF 775
Query: 261 RAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSA 85
+ VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA
Sbjct: 776 NQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSA 835
Query: 84 FVYKEIL 64
+ + I+
Sbjct: 836 YFFTSII 842
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 139 bits (337), Expect = 7e-33
Identities = 69/199 (34%), Positives = 109/199 (54%), Gaps = 1/199 (0%)
Frame = -3
Query: 639 VAEKKCKRRLPVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 460
+A K+ P + T+EE+++++G +DFF V +YT L+ E + + + L D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGTLQD 329
Query: 459 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 280
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 279 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 103
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 102 TPRKSAFVYKEILRSRVID 46
P SA Y +I+R+ ++
Sbjct: 448 VPYTSAKEYAKIIRNNGLE 466
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 139 bits (336), Expect = 9e-33
Identities = 70/199 (35%), Positives = 109/199 (54%), Gaps = 1/199 (0%)
Frame = -3
Query: 639 VAEKKCKRRLPVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 460
+A K+ P + T+EE+++++G +DFF V + T L+ E + R + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTTRLIKYQE--NKRGELGILQD 329
Query: 459 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 280
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 279 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 103
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 102 TPRKSAFVYKEILRSRVID 46
P SA Y +I+R+ ++
Sbjct: 448 VPYTSAKEYAKIIRNNGLE 466
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 124 bits (299), Expect = 3e-28
Identities = 62/194 (31%), Positives = 101/194 (52%), Gaps = 2/194 (1%)
Frame = -3
Query: 639 VAEKKCKRRLPVVQNSGITDEERELVRGASDFFGVNHYTG-FLVSANEQISDRPTIPILP 463
+ K ++ L + + + +E+ ++G SDF G+ H+T ++ N P+
Sbjct: 307 IGRKSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITERNYPSRQGPSYQNDR 366
Query: 462 DITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSP-PTNGLL 286
D+ + P WP S WL P L + Q +Y DP Y+ ENG S L
Sbjct: 367 DLI--ELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYGDPPIYVMENGASQKFHCTQLC 424
Query: 285 DDDRIRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARP 106
D+ RI+Y + + +L + G +KGY +WSL+D FEW +GY++R+G Y V+F+D +P
Sbjct: 425 DEWRIQYLKGYINEMLKAIKDGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKP 484
Query: 105 RTPRKSAFVYKEIL 64
R P+ S YK+I+
Sbjct: 485 RYPKASVQYYKKII 498
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 117 bits (282), Expect = 3e-26
Identities = 69/176 (39%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYW 406
T+EE+ +R +D F +N Y +V + P+ D + P WP +A
Sbjct: 622 TEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN- 678
Query: 405 LTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC-- 232
+P L ++++ Y D YITENG N D DRI Y++ + L
Sbjct: 679 -RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYR 736
Query: 231 LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 737 LD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 791
Score = 115 bits (277), Expect = 1e-25
Identities = 63/187 (33%), Positives = 106/187 (56%), Gaps = 5/187 (2%)
Frame = -3
Query: 609 PVVQNSGITDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPE 430
PV Q T+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 91 PVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHV 148
Query: 429 WPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYY 262
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y+
Sbjct: 149 WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYF 207
Query: 261 RAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSA 85
+ VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA
Sbjct: 208 NQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSA 267
Query: 84 FVYKEIL 64
+ + I+
Sbjct: 268 YFFTSII 274
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 84.6 bits (200), Expect = 3e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -3
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 211
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 210 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = -3
Query: 588 ITDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEW 427
+T+ ER L++G DF +NH+T V +EQ+ SDR I L DIT
Sbjct: 806 LTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT--------- 854
Query: 426 PQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA-- 253
S+ L + P + L ++++ Y D YIT +G + L+DDR+R Y
Sbjct: 855 RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKY 910
Query: 252 LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 911 LQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 84.6 bits (200), Expect = 3e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -3
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 211
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 210 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = -3
Query: 588 ITDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEW 427
+T+ ER L++G DF +NH+T V +EQ+ SDR I L DIT
Sbjct: 806 LTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT--------- 854
Query: 426 PQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA-- 253
S+ L + P + L ++++ Y D YIT +G + L+DDR+R Y
Sbjct: 855 RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKY 910
Query: 252 LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 911 LQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 84.6 bits (200), Expect = 3e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -3
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 211
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 210 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = -3
Query: 588 ITDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEW 427
+T+ ER L++G DF +NH+T V +EQ+ SDR I L DIT
Sbjct: 806 LTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT--------- 854
Query: 426 PQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA-- 253
S+ L + P + L ++++ Y D YIT +G + L+DDR+R Y
Sbjct: 855 RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKY 910
Query: 252 LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 911 LQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 2e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -3
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 2e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -3
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 2e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -3
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -3
Query: 399 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 226
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 116 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 174
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 175 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 228
Score = 51.6 bits (118), Expect = 2e-06
Identities = 53/184 (28%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQS 418
T++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 517 TEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNS 568
Query: 417 ASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAAL 250
S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 569 PSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYIN 623
Query: 249 ESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 70
E++ + GI L GY A+S D RFGLY +D P+ K Y++
Sbjct: 624 EALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRK 673
Query: 69 ILRS 58
I+ S
Sbjct: 674 IIDS 677
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -3
Query: 399 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 226
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 51.6 bits (118), Expect = 2e-06
Identities = 53/184 (28%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQS 418
T++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 790 TEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNS 841
Query: 417 ASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAAL 250
S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 842 PSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYIN 896
Query: 249 ESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 70
E++ + GI L GY A+S D RFGLY +D P+ K Y++
Sbjct: 897 EALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRK 946
Query: 69 ILRS 58
I+ S
Sbjct: 947 IIDS 950
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -3
Query: 399 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 226
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -3
Query: 399 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 226
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 51.6 bits (118), Expect = 2e-06
Identities = 53/184 (28%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQS 418
T++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 790 TEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNS 841
Query: 417 ASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAAL 250
S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 842 PSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYIN 896
Query: 249 ESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 70
E++ + GI L GY A+S D RFGLY +D P+ K Y++
Sbjct: 897 EALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRK 946
Query: 69 ILRS 58
I+ S
Sbjct: 947 IIDS 950
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -3
Query: 399 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 226
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 225 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 51.6 bits (118), Expect = 2e-06
Identities = 53/184 (28%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Frame = -3
Query: 585 TDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQS 418
T++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 790 TEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNS 841
Query: 417 ASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAAL 250
S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 842 PSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYIN 896
Query: 249 ESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 70
E++ + GI L GY A+S D RFGLY +D P+ K Y++
Sbjct: 897 EALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRK 946
Query: 69 ILRS 58
I+ S
Sbjct: 947 IIDS 950
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = -3
Query: 588 ITDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEW 427
+T+ ER L++G DF +NH+T V +EQ+ SDR I L DIT
Sbjct: 67 LTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT--------- 115
Query: 426 PQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA-- 253
S+ L + P + L ++++ Y D YIT +G + L+DDR+R Y
Sbjct: 116 RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKY 171
Query: 252 LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 172 LQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 210
>U83246-1|AAC15920.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein.
Length = 386
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 288 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 341
>AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein.
Length = 481
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein.
Length = 517
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 292 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 345
>BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein.
Length = 540
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 321 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 374
>BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 6.1
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
>AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein.
Length = 446
Score = 30.3 bits (65), Expect = 6.1
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 232 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 281
>AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related
protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 6.1
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
>AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation
factor 1 variant protein.
Length = 208
Score = 30.3 bits (65), Expect = 6.1
Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = -2
Query: 112 PPSHPAQV-RLRLQGDLEKQGHRPR 41
PP HPA + R R G L +GHRPR
Sbjct: 71 PPPHPASISRPRPPGPLPLRGHRPR 95
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,972,809
Number of Sequences: 237096
Number of extensions: 2302270
Number of successful extensions: 5630
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 5346
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5582
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7141427170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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