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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV11e01r
         (683 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A...   307   1e-82
UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B...   224   2e-77
UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylace...   236   4e-61
UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p ...   232   5e-60
UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 pr...   228   8e-59
UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-co...   225   8e-58
UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   211   1e-53
UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; ...   209   5e-53
UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   205   9e-52
UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   204   1e-51
UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   204   2e-51
UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   204   2e-51
UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   200   2e-50
UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   191   2e-47
UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   188   1e-46
UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   188   1e-46
UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   186   6e-46
UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   186   6e-46
UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   183   4e-45
UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   182   1e-44
UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   181   2e-44
UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family pr...   180   3e-44
UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family pr...   177   2e-43
UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   177   2e-43
UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   176   4e-43
UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   175   1e-42
UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   175   1e-42
UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   174   2e-42
UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre...   174   2e-42
UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   173   3e-42
UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; S...   173   3e-42
UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family pr...   172   6e-42
UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   172   6e-42
UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   171   1e-41
UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   171   1e-41
UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Eu...   171   1e-41
UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family pr...   171   1e-41
UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   170   3e-41
UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase ...   169   5e-41
UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;...   168   1e-40
UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family pr...   168   1e-40
UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Re...   167   2e-40
UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   167   2e-40
UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   167   2e-40
UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctiona...   167   3e-40
UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   166   5e-40
UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; ...   165   9e-40
UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   165   9e-40
UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   165   1e-39
UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   164   2e-39
UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   164   2e-39
UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Th...   164   2e-39
UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   163   4e-39
UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   163   5e-39
UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaste...   162   6e-39
UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   162   8e-39
UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-D...   161   1e-38
UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp...   161   1e-38
UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; ...   161   1e-38
UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family pr...   161   1e-38
UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: B...   161   1e-38
UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;...   161   1e-38
UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase...   161   1e-38
UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiale...   160   3e-38
UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium di...   160   3e-38
UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus ter...   158   1e-37
UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; ...   157   2e-37
UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...   157   2e-37
UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   157   3e-37
UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   156   5e-37
UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   156   5e-37
UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   155   7e-37
UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   155   9e-37
UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farci...   155   1e-36
UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   154   2e-36
UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   153   3e-36
UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; ...   153   4e-36
UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   152   7e-36
UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   152   9e-36
UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   151   1e-35
UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   151   2e-35
UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   151   2e-35
UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisom...   150   3e-35
UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep...   150   4e-35
UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   150   4e-35
UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7...   149   5e-35
UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   149   5e-35
UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; c...   148   1e-34
UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; ...   147   2e-34
UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lm...   147   3e-34
UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family pr...   146   3e-34
UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   146   4e-34
UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   146   6e-34
UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase...   146   6e-34
UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   145   1e-33
UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   145   1e-33
UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomy...   145   1e-33
UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   144   2e-33
UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   144   2e-33
UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   144   2e-33
UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; ...   144   2e-33
UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family pr...   143   3e-33
UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584...   143   4e-33
UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family pr...   143   4e-33
UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydr...   142   5e-33
UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;...   142   5e-33
UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   142   9e-33
UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   141   1e-32
UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   141   1e-32
UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   141   1e-32
UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom...   141   1e-32
UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   141   2e-32
UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   140   3e-32
UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; ...   140   4e-32
UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifu...   139   5e-32
UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family pr...   139   7e-32
UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   138   1e-31
UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   138   1e-31
UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   138   2e-31
UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   137   2e-31
UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   137   2e-31
UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   137   3e-31
UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;...   136   4e-31
UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; F...   136   5e-31
UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_030014...   135   8e-31
UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   134   1e-30
UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   134   2e-30
UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   134   3e-30
UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;...   134   3e-30
UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate i...   134   3e-30
UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   133   3e-30
UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   132   6e-30
UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   132   6e-30
UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family pr...   132   8e-30
UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   132   1e-29
UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   132   1e-29
UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;...   131   2e-29
UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family pr...   130   3e-29
UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family pr...   130   3e-29
UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - P...   130   4e-29
UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate iso...   130   4e-29
UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   129   5e-29
UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   129   5e-29
UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   128   1e-28
UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   128   1e-28
UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomy...   128   2e-28
UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   127   2e-28
UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family pr...   127   2e-28
UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albic...   127   2e-28
UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase...   127   2e-28
UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   126   7e-28
UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; ...   126   7e-28
UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; E...   126   7e-28
UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; E...   125   9e-28
UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomy...   125   1e-27
UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   124   2e-27
UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...   124   2e-27
UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase...   124   2e-27
UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISO...   123   4e-27
UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; ...   123   5e-27
UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   123   5e-27
UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albic...   121   1e-26
UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifu...   121   2e-26
UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   120   2e-26
UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Asc...   120   4e-26
UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria...   119   8e-26
UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gam...   119   8e-26
UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d...   118   2e-25
UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid...   118   2e-25
UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   118   2e-25
UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   117   2e-25
UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - P...   117   3e-25
UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   115   1e-24
UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;...   115   1e-24
UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-co...   114   2e-24
UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   113   3e-24
UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   113   5e-24
UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; ...   112   7e-24
UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   112   9e-24
UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep...   111   1e-23
UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   111   2e-23
UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   111   2e-23
UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; ...   111   2e-23
UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   110   3e-23
UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family pr...   110   3e-23
UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   110   4e-23
UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; ...   109   6e-23
UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d...   109   8e-23
UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   109   8e-23
UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   109   8e-23
UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   109   8e-23
UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella per...   108   1e-22
UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohept...   108   1e-22
UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; ...   107   2e-22
UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; ...   107   2e-22
UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:...   106   4e-22
UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   106   6e-22
UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   105   1e-21
UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   104   2e-21
UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...   104   2e-21
UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   103   3e-21
UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   103   3e-21
UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family pr...   103   3e-21
UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium ja...   103   5e-21
UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=...   103   5e-21
UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP020...   102   7e-21
UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase fa...   101   1e-20
UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep...   101   1e-20
UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family pr...   101   2e-20
UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   101   2e-20
UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   101   2e-20
UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-h...   100   3e-20
UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; ...   100   3e-20
UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; ...    98   2e-19
UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    98   2e-19
UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - P...    97   3e-19
UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    97   5e-19
UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    96   8e-19
UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    95   2e-18
UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family pr...    94   2e-18
UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:...    94   3e-18
UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family pr...    93   4e-18
UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; ...    93   4e-18
UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    93   6e-18
UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;...    93   6e-18
UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    93   8e-18
UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre...    93   8e-18
UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|R...    92   1e-17
UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    91   2e-17
UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    91   2e-17
UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family pr...    91   2e-17
UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family pr...    90   4e-17
UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Ge...    90   5e-17
UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family pr...    90   5e-17
UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Prot...    89   7e-17
UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:...    89   1e-16
UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    88   2e-16
UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    88   2e-16
UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    88   2e-16
UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom...    88   2e-16
UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    87   4e-16
UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family pr...    87   5e-16
UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    87   5e-16
UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xan...    86   9e-16
UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    86   9e-16
UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...    85   1e-15
UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    85   1e-15
UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    85   2e-15
UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    85   2e-15
UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate is...    85   2e-15
UniRef50_Q2BPV1 Cluster: Putative uncharacterized protein; n=4; ...    85   2e-15
UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    85   2e-15
UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    84   4e-15
UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    84   4e-15
UniRef50_Q88M65 Cluster: Fumarylacetoacetate hydrolase family pr...    83   8e-15
UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    82   1e-14
UniRef50_Q15XL1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    81   2e-14
UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family pr...    81   3e-14
UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14; Proteo...    81   3e-14
UniRef50_A4SV99 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    81   3e-14
UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    80   6e-14
UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family pr...    72   1e-13
UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXY...    78   2e-13
UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3; Betaproteobact...    77   3e-13
UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    77   3e-13
UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1; ...    77   3e-13
UniRef50_A1UG87 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    77   3e-13
UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Re...    77   5e-13
UniRef50_Q97VT9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    76   7e-13
UniRef50_Q0LGD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    76   9e-13
UniRef50_Q7WPF0 Cluster: Putative fumarylacetoacetate hydrolase ...    73   5e-12
UniRef50_Q0S954 Cluster: Possible hydratase; n=3; Actinomycetale...    73   5e-12
UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase ...    73   9e-12
UniRef50_Q4AQ85 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    72   1e-11
UniRef50_Q2W964 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    72   2e-11
UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family pr...    71   2e-11
UniRef50_A3SNB2 Cluster: Fumarylacetoacetate hydrolase family pr...    71   2e-11
UniRef50_A4QX03 Cluster: Putative uncharacterized protein; n=1; ...    71   2e-11
UniRef50_Q18X79 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    71   3e-11
UniRef50_Q02AF6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    69   1e-10
UniRef50_Q4D6U8 Cluster: Putative uncharacterized protein; n=2; ...    68   2e-10
UniRef50_Q7MXX3 Cluster: Fumarylacetoacetate hydrolase family pr...    67   3e-10
UniRef50_Q395G4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    67   3e-10
UniRef50_Q3WGU5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    67   3e-10
UniRef50_Q6F7V5 Cluster: Putative uncharacterized protein; n=2; ...    66   6e-10
UniRef50_Q0SB97 Cluster: Possible fumarylacetoacetate hydrolase ...    66   6e-10
UniRef50_Q4J6K3 Cluster: 4-hydroxyphenylacetate degradation bifu...    66   6e-10
UniRef50_Q3II31 Cluster: Putative fumarylacetoacetate hydrolase ...    66   8e-10
UniRef50_Q4J7I6 Cluster: Conserved protein; n=3; Thermoprotei|Re...    66   1e-09
UniRef50_Q0AN49 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    65   1e-09
UniRef50_Q6KZ97 Cluster: Fumarylacetoacetase; n=2; Thermoplasmat...    65   2e-09
UniRef50_Q6MNK0 Cluster: Putative uncharacterized protein; n=1; ...    64   3e-09
UniRef50_Q8D6F8 Cluster: 2-keto-4-pentenoate hydratase; n=22; Pr...    62   1e-08
UniRef50_A7K1Y8 Cluster: Fumarylacetoacetate hydrolase family pr...    62   1e-08
UniRef50_Q3E159 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    61   3e-08
UniRef50_Q9CKS8 Cluster: HpaG; n=1; Pasteurella multocida|Rep: H...    60   4e-08
UniRef50_Q60C48 Cluster: Fumarylacetoacetate hydrolase family pr...    60   4e-08
UniRef50_Q8KDK4 Cluster: Fumarylacetoacetate hydrolase family pr...    60   7e-08
UniRef50_Q7UMG2 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    60   7e-08
UniRef50_Q5KYI4 Cluster: Hypothetical conserved protein; n=3; Ba...    60   7e-08
UniRef50_A0VBW0 Cluster: 4-hydroxyphenylacetate degradation bifu...    60   7e-08
UniRef50_Q4FWM5 Cluster: Putative uncharacterized protein; n=3; ...    59   9e-08
UniRef50_Q5B6D4 Cluster: Putative uncharacterized protein; n=1; ...    59   9e-08
UniRef50_A7D1J1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    59   9e-08
UniRef50_A1TDQ7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    59   1e-07
UniRef50_A5EF32 Cluster: Putative Fumarylacetoacetate (FAA) hydr...    58   2e-07
UniRef50_Q44SK1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    57   3e-07
UniRef50_A5VED2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    57   5e-07
UniRef50_A3VRL8 Cluster: Putative isomerase-decarboxylase-like p...    54   3e-06
UniRef50_A0SP98 Cluster: Fumarylacetoacetate hydrolase family pr...    54   4e-06
UniRef50_A3IA41 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    53   7e-06
UniRef50_A7QL05 Cluster: Chromosome undetermined scaffold_116, w...    52   1e-05
UniRef50_A1SUQ4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    52   1e-05
UniRef50_Q9KDZ0 Cluster: BH1071 protein; n=2; Bacillus|Rep: BH10...    52   2e-05
UniRef50_Q5V2I1 Cluster: Fumarylacetoacetate hydrolase family pr...    50   4e-05
UniRef50_Q1GRD3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    50   5e-05
UniRef50_A6Q9W9 Cluster: Fumarylacetoacetate hydrolase; n=1; Sul...    50   5e-05
UniRef50_Q5DHL1 Cluster: SJCHGC00506 protein; n=2; Schistosoma j...    49   9e-05
UniRef50_A6C0W6 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    48   2e-04
UniRef50_A3VNC8 Cluster: Possible isomerase/decarboxylase; n=1; ...    48   2e-04
UniRef50_Q0HT13 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    48   3e-04
UniRef50_Q2UV71 Cluster: Predicted protein; n=1; Aspergillus ory...    46   7e-04
UniRef50_A2UC21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    42   0.014
UniRef50_A6Q508 Cluster: Fumarylacetoacetate hydrolase family pr...    41   0.024
UniRef50_A7Q3E6 Cluster: Chromosome chr13 scaffold_48, whole gen...    39   0.13 
UniRef50_Q4RJI4 Cluster: Chromosome 3 SCAF15037, whole genome sh...    38   0.30 
UniRef50_Q1IPR5 Cluster: Fe-S protein, radical SAM family; n=5; ...    36   0.92 
UniRef50_Q10JF6 Cluster: Isomerase, putative; n=10; Magnoliophyt...    36   1.2  
UniRef50_Q6FUW3 Cluster: Similarities with sp|P08640 Saccharomyc...    36   1.2  
UniRef50_Q5B250 Cluster: Putative uncharacterized protein; n=1; ...    36   1.2  
UniRef50_Q4X003 Cluster: Alpha-L-arabinofuranosidase A; n=7; Pez...    36   1.2  
UniRef50_Q600A8 Cluster: Glucose-6-phosphate isomerase; n=3; Myc...    35   2.1  
UniRef50_UPI0000E82426 Cluster: PREDICTED: hypothetical protein;...    34   2.8  
UniRef50_Q6YRJ1 Cluster: Putative uncharacterized protein; n=1; ...    34   3.7  
UniRef50_Q0TRU3 Cluster: Putative permease; n=1; Clostridium per...    34   3.7  
UniRef50_A3Y335 Cluster: Putative uncharacterized protein; n=3; ...    33   4.9  
UniRef50_UPI000023CD17 Cluster: predicted protein; n=1; Gibberel...    33   6.5  
UniRef50_Q0D850 Cluster: Os07g0184600 protein; n=3; Oryza sativa...    33   6.5  
UniRef50_Q245B0 Cluster: Putative uncharacterized protein; n=1; ...    33   6.5  
UniRef50_Q0UDT0 Cluster: Predicted protein; n=1; Phaeosphaeria n...    33   6.5  
UniRef50_P00815 Cluster: Histidine biosynthesis trifunctional pr...    33   8.6  

>UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A;
           n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase
           isoform A - Bombyx mori (Silk moth)
          Length = 330

 Score =  307 bits (754), Expect = 1e-82
 Identities = 129/216 (59%), Positives = 172/216 (79%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           +HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+  ++++ DV+K V  E+
Sbjct: 115 IHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEV 174

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL VV+G++AS V    A  +V GYT+AQDI A DW+K K + Q LLGK+MDTFCP+GP 
Sbjct: 175 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPC 234

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           ++TSDE+G    L V CS+NGV KQ S+T Q +H IP ++ R+S+VMTL+PGD+ILTGTP
Sbjct: 235 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 294

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 34
           GGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F
Sbjct: 295 GGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 330


>UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B;
           n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase
           isoform B - Bombyx mori (Silk moth)
          Length = 360

 Score =  224 bits (547), Expect(2) = 2e-77
 Identities = 97/158 (61%), Positives = 125/158 (79%)
 Frame = -3

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E+EL VV+G++AS V    A  +V GYT+AQDI A DW+K K + Q LLGK+MDTFCP+G
Sbjct: 203 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG 262

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           P ++TSDE+G    L V CS+NGV KQ S+T Q +H IP ++ R+S+VMTL+PGD+ILTG
Sbjct: 263 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 322

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 34
           TPGGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F
Sbjct: 323 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 360



 Score = 88.6 bits (210), Expect(2) = 2e-77
 Identities = 31/55 (56%), Positives = 47/55 (85%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517
           +HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+  ++++ DV+K+
Sbjct: 115 IHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKS 169


>UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to
           fumarylacetoacetate hydrolase domain containing 2A
           isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar
           to fumarylacetoacetate hydrolase domain containing 2A
           isoform 2 - Apis mellifera
          Length = 334

 Score =  236 bits (577), Expect = 4e-61
 Identities = 112/210 (53%), Positives = 146/210 (69%), Gaps = 1/210 (0%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           DK+ CVGLNY  HC+EQ ++PPE P IF+KF S ++GP D I L   +S  V  E EL +
Sbjct: 125 DKLACVGLNYIGHCKEQGVSPPESPVIFSKFASNIIGPRDNIMLP-PISDKVDWEAELAI 183

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS-QLLLGKAMDTFCPIGPWIVT 313
           VIGKK   ++++   DY+ GYTIAQDI A DW+K+K+   Q LLGKAMDTFCP+GP +VT
Sbjct: 184 VIGKKCKALNNNEGEDYIFGYTIAQDITARDWQKSKRNGGQFLLGKAMDTFCPLGPAVVT 243

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
            + I +  NL VK  +NG  KQ  NT++ I K  +I+A +S  MTLLPGD+ILTGTP GV
Sbjct: 244 KEAISDINNLTVKTWVNGNIKQDGNTSELIFKPHEIVAYISQFMTLLPGDVILTGTPSGV 303

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G  R PPE+LQ GDV+ +EI+ +G    +V
Sbjct: 304 GFTRKPPEYLQRGDVLETEIQGLGRLRNKV 333


>UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p -
           Drosophila melanogaster (Fruit fly)
          Length = 293

 Score =  232 bits (568), Expect = 5e-60
 Identities = 105/202 (51%), Positives = 140/202 (69%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+GLNY+DHC+EQ    P+ P  F+KF + +VGP D + +    S  +  E+EL  V
Sbjct: 84  KIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNV-IAHAASSKIDWEVELVCV 142

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK A +V  S A DYV GY++AQDI A DW+K +   Q L+GK+MDTF P+GP +V   
Sbjct: 143 IGKVARQVPKSQAMDYVFGYSVAQDISARDWQKERNGGQFLMGKSMDTFLPLGPAVVHKS 202

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
            + +  NLN+K  +NGV+KQ  NT   I K+ D+I RLS  +TLLPGDII+TGTP GVG+
Sbjct: 203 LVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLPGDIIVTGTPKGVGM 262

Query: 126 YRNPPEFLQPGDVITSEIENIG 61
           +R PPEFLQPGDV+ SEI  +G
Sbjct: 263 HRTPPEFLQPGDVVQSEIVGLG 284


>UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105
           protein; n=2; Gallus gallus|Rep: PREDICTED: similar to
           CGI-105 protein - Gallus gallus
          Length = 406

 Score =  228 bits (558), Expect = 8e-59
 Identities = 102/209 (48%), Positives = 142/209 (67%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +KV+CVGLNY+DHC EQ +  P+ P IF+KFPS + GP D I    + S+ V  E+EL  
Sbjct: 198 EKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAESSE-VDWEVELAA 256

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           +IGK    +  S A ++++G+T+A D+ A DW+  +   Q LLGK  DTFCPIGP IVT 
Sbjct: 257 IIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFDTFCPIGPAIVTK 316

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           D + +  NL ++CS+NG   Q S+TNQ I ++P ++A +S  +TL PGD++LTGTP GVG
Sbjct: 317 DSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTLRPGDVLLTGTPPGVG 376

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
           V+R PP FL+PGD +  EIE +GT   +V
Sbjct: 377 VFRKPPMFLKPGDEVQCEIEELGTICNKV 405


>UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase
           domain-containing protein 2B; n=41; cellular
           organisms|Rep: Fumarylacetoacetate hydrolase
           domain-containing protein 2B - Homo sapiens (Human)
          Length = 314

 Score =  225 bits (550), Expect = 8e-58
 Identities = 103/209 (49%), Positives = 138/209 (66%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           DKV+CVG+NY DHC+EQ +  P+ P IF+KF S++VGP D + L    S+ V  E+EL V
Sbjct: 106 DKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQ-SQEVDWEVELAV 164

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGKK   + ++ A  +V G+T+A D+ A DW   +   Q LLGK  DTFCP+GP +VT 
Sbjct: 165 VIGKKGKHIKATDAMAHVAGFTVAHDVSARDWLTRRNGKQWLLGKTFDTFCPLGPALVTK 224

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           D + +P NL + C +NG   Q SNTNQ + K  D+IA +S  +T  PGD+ILTGTP GVG
Sbjct: 225 DSVADPHNLKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPPGVG 284

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
           V+R PP FL+ GD +  EIE +G    +V
Sbjct: 285 VFRKPPVFLKKGDEVQCEIEELGVIINKV 313


>UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=3; cellular organisms|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus
           halodurans
          Length = 319

 Score =  211 bits (515), Expect = 1e-53
 Identities = 100/209 (47%), Positives = 134/209 (64%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVG NY++H  E K   P+ P IF KF +T++GP D + L   +++ +  E EL  V
Sbjct: 103 KIICVGHNYREHILEMKREIPKYPVIFAKFANTIIGPEDNVPLP-SITEQLDYEAELAFV 161

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGKKA  V    A DYV GYTI  DI A D ++  +  Q L GK +D   P+GPW+VT D
Sbjct: 162 IGKKAKDVAKEDALDYVAGYTIVNDITARDLQR--RTIQWLQGKTLDGSLPMGPWLVTKD 219

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI NP  L +  S+NG ++Q+SNT   +  I D++  LS +MTL PGD++ TGTPGGVGV
Sbjct: 220 EIPNPHQLEITLSVNGEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCTGTPGGVGV 279

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
            R P  FLQ GDV+  E+E +GT E RV+
Sbjct: 280 AREPQLFLQDGDVVRIELEKVGTLENRVK 308


>UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 305

 Score =  209 bits (510), Expect = 5e-53
 Identities = 104/218 (47%), Positives = 137/218 (62%), Gaps = 9/218 (4%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+GLNYK+H  E K+  P+ P +F+KF + + GPND+I +K   S  V  E+EL VV
Sbjct: 89  KIICIGLNYKEHANEAKMAIPKEPIVFSKFDNAICGPNDSI-IKPVESDEVDYEVELVVV 147

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK+A  V  S A  YV GYT+  D+ A DW+  K  SQ LLGK  DTF PIGP IV + 
Sbjct: 148 IGKQAKNVSESDALQYVAGYTVGNDVSARDWQLRKNNSQWLLGKTFDTFAPIGPSIVINP 207

Query: 306 EIG--------NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151
           E+         +P NL++KC++NG   Q S T +FI  I  +++ LS + TL PGDII T
Sbjct: 208 EVAALSDDTYFDPNNLSIKCTLNGQVVQNSTTKEFIFNIQTVVSYLSKLFTLNPGDIIFT 267

Query: 150 GTPGGVGVYRNP-PEFLQPGDVITSEIENIGTFETRVE 40
           GTP GVG  R P P FL+ GDVI  EIE +G+    V+
Sbjct: 268 GTPSGVGFIRKPNPIFLKSGDVIKCEIEELGSLVNNVK 305


>UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Pirellula sp.|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Rhodopirellula baltica
          Length = 342

 Score =  205 bits (500), Expect = 9e-52
 Identities = 100/206 (48%), Positives = 128/206 (62%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K+LC+GLNY DH  E     P LP +F+KF S +VG    I L   +S  V  E EL V
Sbjct: 131 EKILCIGLNYLDHAIETGAEKPSLPVVFSKFNSALVGHGQDIVLPK-ISDKVDYEAELVV 189

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK    VD++ A D V GY +  D+ + DW+K +   Q L+GK+ DTF P+GP +VT+
Sbjct: 190 VIGKTVRHVDANEAMDAVFGYAVGHDVSSRDWQKGRPGGQWLVGKSFDTFAPLGPAVVTA 249

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI +P NL ++  ING   Q+S T+Q I  IP +IA LS  MTL PGD+I TGTP GVG
Sbjct: 250 DEISDPGNLPIRLHINGETLQESKTDQLIFDIPALIAHLSKFMTLKPGDLIFTGTPSGVG 309

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFE 52
             R PP +L PGD    EI+ IG  E
Sbjct: 310 DARTPPRYLAPGDRCVVEIDGIGRLE 335


>UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase; n=1;
           Blastopirellula marina DSM 3645|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase -
           Blastopirellula marina DSM 3645
          Length = 284

 Score =  204 bits (499), Expect = 1e-51
 Identities = 102/208 (49%), Positives = 129/208 (62%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+CVGLNY DH +E   T  + P IFNKFPS ++  +D I L  + S+ V  E EL V 
Sbjct: 75  KVICVGLNYADHAKETGATVGDEPVIFNKFPSALIADHDEIHLPPESSQ-VDYEAELVVA 133

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG     +    A  +V GY    DI A DW+K K   Q LLGK  DTF P+GP + T D
Sbjct: 134 IGTAGKHIPQGEAMSHVGGYCCGNDISARDWQKGKPGKQWLLGKTFDTFAPLGPVLYTPD 193

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +P NL ++C +NG   Q+S+T+Q I KI  +I+ LSNV+ L PGD+I TGTP GVGV
Sbjct: 194 EIADPNNLAIRCRLNGETMQESSTSQLIFKIDFLISYLSNVVMLQPGDLIFTGTPHGVGV 253

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
            R+P  FLQPGD +  EIE +G    RV
Sbjct: 254 ARDPQVFLQPGDQVEVEIEGLGLLTNRV 281


>UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Planctomyces maris DSM 8797|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Planctomyces maris DSM 8797
          Length = 290

 Score =  204 bits (498), Expect = 2e-51
 Identities = 99/209 (47%), Positives = 133/209 (63%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KVLC+GLNY+DH EE  +  P+ P  F+KF S+V G    I++   V++ V  E EL  V
Sbjct: 80  KVLCIGLNYRDHAEETGMPFPDEPVCFSKFSSSVTGSGQPIRIP-SVAREVDYEAELVAV 138

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    V  ++A DYV GY    D+ A DW+  +   Q LLGK  DTF P GP++VT+D
Sbjct: 139 IGKTCRNVTQANASDYVAGYMNGHDVSARDWQIGRPGGQWLLGKTADTFAPTGPYLVTAD 198

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI N  +L++K ++NG   Q SNT++FI  I ++IA +S ++TL PGDII TGTP GVG+
Sbjct: 199 EIKNANSLSIKLTLNGEVLQNSNTDKFIFTIEEVIAFVSQILTLEPGDIIFTGTPPGVGM 258

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
            R PP +LQPGD    EI+ +G     VE
Sbjct: 259 ARKPPVYLQPGDQACIEIQGLGMLHNTVE 287


>UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Ectothiorhodospiraceae|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Halorhodospira halophila (strain DSM 244 / SL1)
           (Ectothiorhodospirahalophila (strain DSM 244 / SL1))
          Length = 316

 Score =  204 bits (497), Expect = 2e-51
 Identities = 98/218 (44%), Positives = 131/218 (60%), Gaps = 6/218 (2%)
 Frame = -3

Query: 678 HGNDKVLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517
           H    V+C+GLNY DH  E +      L  PE P +F K  ++V GP D   L   V+  
Sbjct: 96  HPPRNVICLGLNYADHARESQQAKGDELALPEAPVVFTKATTSVAGPYDDFILDPSVTSE 155

Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337
           +  E+EL VVIG+    +    A  +V GYT+  D+ A D +   K  Q  LGK++D  C
Sbjct: 156 LDWEVELAVVIGRGGRHIREQDALQHVFGYTVVNDLSARDLQFRHK--QFFLGKSVDGSC 213

Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
           P+GPWI T++ + NP NL + C IN   +Q+S+T + +  IP IIA LS VMTL+PGDII
Sbjct: 214 PMGPWITTANAVPNPHNLALSCRINDTTEQQSHTGEMVFSIPRIIAELSRVMTLIPGDII 273

Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            TGTP GVG  R PP FLQ GD++TSE+E +GT   R+
Sbjct: 274 ATGTPAGVGFARTPPRFLQAGDIVTSEVEGLGTLRNRI 311


>UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 293

 Score =  200 bits (489), Expect = 2e-50
 Identities = 102/216 (47%), Positives = 131/216 (60%), Gaps = 7/216 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE-------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505
           V C+G NY  H EE       Q    PE P  F+K  +TV+GP+D I    + S+ +  E
Sbjct: 74  VFCMGWNYLTHFEEGRGRREGQGEELPEYPTFFDKPTTTVIGPHDDIPFDPNFSEKIDYE 133

Query: 504 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 325
            EL VVIG+    + +  A D+V GYT A D+ A D ++     Q L GK MD  CP+GP
Sbjct: 134 AELAVVIGRSGRSIPAGEAMDHVFGYTAANDVTARDVQRRHG-GQWLKGKGMDGSCPLGP 192

Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
           WIVT+DEI + QNL V+C +NGVQKQ SNT   +  +  +I  LS  MTLLPGD++LTGT
Sbjct: 193 WIVTADEIPDVQNLQVQCRVNGVQKQNSNTRFMVFPVARLIEELSLAMTLLPGDVLLTGT 252

Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           P GVG  R PPEFL+PGD +T  +E +G    RV E
Sbjct: 253 PEGVGYARTPPEFLRPGDEVTVYVEGVGEISNRVVE 288


>UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Oceanobacillus iheyensis|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Oceanobacillus iheyensis
          Length = 301

 Score =  191 bits (465), Expect = 2e-47
 Identities = 92/210 (43%), Positives = 132/210 (62%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+CVG NY +H  E K   PE P +F KF + ++GP + I     +++ +  E+ELT+V
Sbjct: 94  KVICVGKNYAEHVAEMKSEIPEFPVLFAKFDNAIIGPEEEIHYS-SLTEKLDYEVELTIV 152

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++AS V    A DYV GYTI  D  A D +K  +  Q L GK++D   PIGPW+VT D
Sbjct: 153 IGREASHVFEEEALDYVAGYTIGNDTSARDLQK--RTPQWLQGKSLDHTTPIGPWVVTKD 210

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +P NL +   +N  ++Q SNT   I  +P +++ +SN++TL PGDII+TGTP GVG 
Sbjct: 211 EIVDPGNLTIASYVNNEKRQYSNTKHLIFSVPYLVSFISNLITLKPGDIIMTGTPDGVGF 270

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37
             +PP +++  D +  EIE IG  E  V++
Sbjct: 271 AMDPPGYVKDKDKVKLEIEGIGIMENMVKK 300


>UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Solibacter usitatus Ellin6076|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Solibacter usitatus (strain Ellin6076)
          Length = 269

 Score =  188 bits (457), Expect = 1e-46
 Identities = 95/202 (47%), Positives = 127/202 (62%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+GLNY+DH EE K+  PE P +F K+ +TV G    I L  + S+    E EL VV
Sbjct: 61  KIICIGLNYRDHAEEAKMPIPETPTVFAKWGNTVTGHQHPIVLPKN-SRKPDYEAELAVV 119

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    +  ++  ++V GYTI  D+ A D++     SQ  +GK  DTF PIGPWIVT+D
Sbjct: 120 IGKGGRHIAEANWREHVFGYTILNDVSARDFQM--ATSQWTIGKTFDTFAPIGPWIVTTD 177

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +P  L +  ++N V  Q SNT+  I  IP +IA LS+VM+L PGDII TGTP GVG 
Sbjct: 178 EIEDPGALRISLTLNSVTMQDSNTSNLIFGIPKLIAYLSSVMSLEPGDIISTGTPAGVGF 237

Query: 126 YRNPPEFLQPGDVITSEIENIG 61
            + PP +L PGDV   ++  IG
Sbjct: 238 AQKPPRWLVPGDVCAIQVGGIG 259


>UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Opitutaceae bacterium TAV2|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Opitutaceae bacterium TAV2
          Length = 279

 Score =  188 bits (457), Expect = 1e-46
 Identities = 96/208 (46%), Positives = 120/208 (57%), Gaps = 1/208 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-SKAVVCEIELTVV 487
           +LC+GLNY+ H EE     PE P +F K  + +  P D I L   + S  V  E EL VV
Sbjct: 69  ILCIGLNYRRHAEETHARIPEFPVLFMKGVNALQNPGDPIMLPTHLRSDEVDYECELAVV 128

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+    V   HA DYVLGYT A D+ A DW+  +  SQ   GK  DTF P+GP IVT D
Sbjct: 129 IGRTCKNVTRDHALDYVLGYTCANDVSARDWQVKRGGSQWCRGKTFDTFAPLGPAIVTKD 188

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI NP  L +  +++G   Q   T+  I  +P +I  LS   TLLPG +ILTGTP GVG+
Sbjct: 189 EIPNPNALKISTTVSGEVLQDWTTSDMIFDVPALIEFLSGSTTLLPGTVILTGTPHGVGM 248

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
            R PP +L+ GD +  EIE IG  E  V
Sbjct: 249 ARKPPRWLRAGDKVVVEIEKIGRLENPV 276


>UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Acidobacteria bacterium
           Ellin345|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 290

 Score =  186 bits (452), Expect = 6e-46
 Identities = 95/209 (45%), Positives = 128/209 (61%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ +GLNY DH +E   + P+ P  F KF S++ GP D I+L  D    V  E EL VV
Sbjct: 82  KIVAIGLNYLDHAKEAGQSIPKTPLCFAKFTSSLSGPYDPIRLP-DAEAQVDFEGELGVV 140

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK+A +V  S A +YV GY +  D+  ++        Q   GK+ DTF P GP++VT D
Sbjct: 141 IGKRAHRVAESEAMEYVAGYVVFNDV--SERRSQFADGQWTRGKSCDTFSPNGPYLVTRD 198

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +P NL +   +NG   Q SNTNQ I KIP++I+ LS+  T  PGDII TGTP GVG 
Sbjct: 199 EVADPGNLRITTRVNGAVMQDSNTNQLIFKIPELISYLSHSFTFHPGDIIATGTPPGVGF 258

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
            R PP +L+ GD++  EIE++G    RVE
Sbjct: 259 SRKPPLYLREGDLVEVEIESVGRIANRVE 287


>UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=6; Burkholderiales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Burkholderia cenocepacia (strain HI2424)
          Length = 293

 Score =  186 bits (452), Expect = 6e-46
 Identities = 98/220 (44%), Positives = 134/220 (60%), Gaps = 11/220 (5%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLT-----------PPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517
           + CVG NY +H  E + +            PE P IF K  STV+GP+  I   + V+  
Sbjct: 77  IFCVGKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTVIGPSAKIPRHVGVTAQ 136

Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337
           +  E EL VVIGK    +  + A +YV GYT+  D  A D +K  +  Q  LGK++D FC
Sbjct: 137 LDYEAELGVVIGKGGRGIKKADAMNYVFGYTVINDFTARDLQKLHR--QWFLGKSLDGFC 194

Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
           P+GP+++TSDE+ N QN+++KC +NG  +Q SNT++ I  IP +I  LS  + L PGD+I
Sbjct: 195 PMGPFVITSDEV-NGQNIDIKCWVNGELRQNSNTSKLIFDIPTLIETLSAGIELQPGDVI 253

Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
            TGTP GVG+  NPP+FLQ GDVI  EI+N+G  E  V E
Sbjct: 254 ATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE 293


>UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Bacillus clausii KSM-K16|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Bacillus clausii (strain KSM-K16)
          Length = 292

 Score =  183 bits (445), Expect = 4e-45
 Identities = 92/211 (43%), Positives = 133/211 (63%), Gaps = 2/211 (0%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K++C+GLNY+ H +E     PE P +F+KF +T+ G    I +   V++A+  E+EL +
Sbjct: 81  EKIICIGLNYRRHADETGSPYPETPILFSKFNNTLTGHGSNIVVP-PVTQALDYEVELAI 139

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK A +V    A +YVLGY  A D+ A D +   K +Q LLGK  D FCPIGP++VT 
Sbjct: 140 VIGKTAKQVTEDEALNYVLGYCTANDLSARDLQM--KTAQWLLGKTCDGFCPIGPFLVTK 197

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV- 133
           ++I +PQNL ++  +NG  KQ+SNT   I    +II+ +S   TL PGDI+LTGTP GV 
Sbjct: 198 EDIADPQNLALETRVNGEIKQQSNTADMIFTCAEIISYVSRHFTLKPGDILLTGTPEGVI 257

Query: 132 -GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            G+      +LQPGD ++  IE +GT   ++
Sbjct: 258 LGLPEAERRYLQPGDTVSVHIEQLGTLTNKL 288


>UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 295

 Score =  182 bits (442), Expect = 1e-44
 Identities = 89/210 (42%), Positives = 130/210 (61%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ +GLNY+DH  E     PE P +F K+ +T+VG  + +++    S+A   E EL VV
Sbjct: 87  KIIAIGLNYEDHANETGAPIPEKPIVFAKYANTLVGAGEEVRIPPITSQADY-EAELAVV 145

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++A  V    A +YV GYT   D+ + D + ++   Q    K++DTFCP+GP++ T D
Sbjct: 146 IGREAKNVSEEEALEYVFGYTNCNDVSSRDLQFSEG-GQWTRSKSLDTFCPLGPYVATRD 204

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +PQ+L ++  +NG   Q SNT++ I  +  +I+ LS  MTL+PGDII TGTP GVG 
Sbjct: 205 EIPDPQSLRIRSVLNGEVMQDSNTSKMIFPVARLISFLSTGMTLVPGDIIATGTPAGVGF 264

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37
            R+P  FL+ GD I+ EIE +G     V E
Sbjct: 265 ARDPKVFLKDGDEISIEIEGLGRLTNPVRE 294


>UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 302

 Score =  181 bits (440), Expect = 2e-44
 Identities = 92/210 (43%), Positives = 126/210 (60%), Gaps = 6/210 (2%)
 Frame = -3

Query: 654 VGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           +GLNY +H  E           P+ P IF+K P+ V   ND I+    V++ +  E EL 
Sbjct: 93  IGLNYTEHVAESARALDTAHELPQQPVIFSKPPTAVAAWNDPIRHNAKVTQQLDWETELA 152

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           V+IG  A  V  + A ++V GYT+  D+ A D    ++  Q ++ K  D+F P+GP IVT
Sbjct: 153 VIIGSTARGVAEADALNHVFGYTVINDVSARDC---RRAGQWIVSKGQDSFAPMGPCIVT 209

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           +DEIG+P NLN+   +NGV+KQ SNT   +  +P +IA ++ VMTL PGDII TGTP GV
Sbjct: 210 ADEIGDPHNLNILTHVNGVEKQNSNTRFMLFNVPQLIADIARVMTLEPGDIIATGTPAGV 269

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G  R+P EFL PGDV+   +E IGT    V
Sbjct: 270 GAGRDPQEFLWPGDVVECTVEGIGTLRNPV 299


>UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=2; Candidatus Pelagibacter ubique|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Pelagibacter ubique
          Length = 281

 Score =  180 bits (438), Expect = 3e-44
 Identities = 86/204 (42%), Positives = 129/204 (63%)
 Frame = -3

Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475
           +GLNY +H +E     P+ P +FNK   ++VGPND + +    SK +  E+E+  VIGKK
Sbjct: 76  IGLNYVEHAKETGAKTPDNPVLFNKSVHSIVGPNDNVIIPK-TSKKLDHEVEIAFVIGKK 134

Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 295
           A +V    A DY+ GY I  DI   +W+K K   Q + GK+ DTF P+GP++VT DEI +
Sbjct: 135 AKRVLEKDAQDYIFGYCICNDISEREWQKEKG-GQWVKGKSGDTFGPLGPYLVTKDEIQD 193

Query: 294 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115
             NLN+   +NG + Q  NTNQ I     ++A +++ +TL+PGDI+ TGTP GVG+  +P
Sbjct: 194 VNNLNLTLDVNGHRHQTGNTNQMIFNFNFLVAHITSFITLMPGDIVTTGTPPGVGLGMDP 253

Query: 114 PEFLQPGDVITSEIENIGTFETRV 43
           P FL+ GD +   I+++G+  ++V
Sbjct: 254 PVFLKEGDEMKLNIDSLGSQNSKV 277


>UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Bacillus sp. B14905|Rep:
           Fumarylacetoacetate hydrolase family protein - Bacillus
           sp. B14905
          Length = 314

 Score =  177 bits (432), Expect = 2e-43
 Identities = 84/204 (41%), Positives = 125/204 (61%), Gaps = 2/204 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           ++C+G NY +H +E   +  P EL  +F K P+ +     T+ +  D+S  +  E EL +
Sbjct: 94  IMCIGKNYNEHAKEMGAEAAPKEL-MVFTKSPTAIAADGQTLSIHADLSSKMDYEGELAI 152

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK+   +  + A+DYV GYTIA DI A D ++  K  Q  LGK+++  CP+GP++VT 
Sbjct: 153 VIGKRGKNIPKNLAYDYVFGYTIANDITARDLQEKHK--QFFLGKSLEGTCPLGPYLVTK 210

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI NPQ+L V   +N   +Q  +T   +  +  +++ LS  +TL PGD+ILTGTP GVG
Sbjct: 211 DEIPNPQDLTVVTKVNDEVRQNGSTKDMMFSVETLVSILSQHVTLEPGDVILTGTPAGVG 270

Query: 129 VYRNPPEFLQPGDVITSEIENIGT 58
              NPP+FL+ GD +   I+ IGT
Sbjct: 271 KGMNPPQFLKAGDTVKVSIQGIGT 294


>UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Symbiobacterium thermophilum|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Symbiobacterium thermophilum
          Length = 294

 Score =  177 bits (431), Expect = 2e-43
 Identities = 89/208 (42%), Positives = 128/208 (61%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+LCVGLNY+ H  E  +  P  P +F KF + V GP D + L   +++    E EL VV
Sbjct: 86  KILCVGLNYRAHAAEAHMAVPAYPVLFAKFQNAVAGPGDPVVLP-SIAEQYDYEAELVVV 144

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++A +V +  A DYVLGY    D+ A   E   + SQ LLGK++D F PIGP++VT D
Sbjct: 145 IGRRARRVPAEAALDYVLGYCNGNDLSAR--ELQMRTSQWLLGKSLDGFLPIGPYLVTRD 202

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +PQ+L ++   NG  +Q  +T   +  + ++IA +S  MTL PGDII TGTP GV +
Sbjct: 203 EVPDPQDLRIRLWRNGEIRQDGHTRNMLFPVAELIAYISRYMTLEPGDIIATGTPEGVIM 262

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                ++L+PGDV+  EI+ +G  E R+
Sbjct: 263 GLAEKDWLKPGDVVAVEIDGLGRLENRL 290


>UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=8; cellular organisms|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Thermoanaerobacter tengcongensis
          Length = 242

 Score =  176 bits (429), Expect = 4e-43
 Identities = 100/209 (47%), Positives = 129/209 (61%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K +CVGLNYKDH EE     PE P +F K  + V+GP+D I L  ++S+ V  E EL VV
Sbjct: 47  KAICVGLNYKDHIEEMGDKIPEEPTLFIKPSTAVIGPDDYIILP-EMSRRVDYEGELAVV 105

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+KA  V    A +Y+LGYTIA D+ A D +   K  Q    K+ DTF PIGPWIVT  
Sbjct: 106 IGRKAKNVSIEEAKNYILGYTIANDVTARDLQA--KDGQWTRAKSFDTFLPIGPWIVTDL 163

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +   P +LN+   +NG  KQKSNT   I  +  +++ +S++MTL PGD+ILTGTP GVG 
Sbjct: 164 D---PTSLNITTYVNGEVKQKSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGP 220

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
                  L+ GDV+T EIE IG    RV+
Sbjct: 221 -------LKSGDVVTIEIEGIGKLTNRVK 242


>UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=3; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Neptuniibacter caesariensis
          Length = 286

 Score =  175 bits (425), Expect = 1e-42
 Identities = 95/208 (45%), Positives = 119/208 (57%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K L VGLNY DH EE  L  PE P  FNK  S V+GPN+ I  +  VS+ +  E EL +V
Sbjct: 74  KFLGVGLNYADHIEETGLDTPEFPTFFNKQSSCVIGPNEAIH-RPTVSEKLDYEGELAIV 132

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    V    A + + G+TI  D+   DW+   K     LGK+ DT  P+GPWIVT+D
Sbjct: 133 IGKACRHVPYEKASEVIAGFTIVNDVSVRDWQI--KSPTWTLGKSFDTHGPMGPWIVTAD 190

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ NP NL +K  +N   +Q SNT   I     +I  LS V TL PGD+I TGT  GVGV
Sbjct: 191 EV-NPHNLELKTWVNDELRQHSNTKHLIFDCYQLIETLSTVCTLQPGDVIATGTSSGVGV 249

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
              P  +++PGD +T EIE IG     V
Sbjct: 250 KMKPRGYMKPGDRVTIEIEGIGKLSNPV 277


>UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase;
           n=1; Pedobacter sp. BAL39|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase -
           Pedobacter sp. BAL39
          Length = 285

 Score =  175 bits (425), Expect = 1e-42
 Identities = 86/211 (40%), Positives = 123/211 (58%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+GLNY DH  E     P  P +F K  + +VGP D I +     K    E+EL +V
Sbjct: 74  KLVCIGLNYADHARETNAPLPPEPVVFMKSTTAIVGPFDQIMIPKGSVKTD-WEVELAIV 132

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGKKAS V+ + A DYV GY +  D+   +++  +       GK  DTF P+GP++ T +
Sbjct: 133 IGKKASYVEEAEALDYVAGYVLHNDVSEREFQIERN-GTWDKGKGCDTFAPLGPFLATKE 191

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +  NL +  S+NG   Q  NT+ FI  +P +++ +S  MTLLPGD+I TGTP GVG+
Sbjct: 192 EIADVNNLRLWLSVNGKMMQDGNTSNFIFNVPFVVSYVSQFMTLLPGDVISTGTPAGVGL 251

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34
              PP +L+ GDV+   I+ +GT    V  F
Sbjct: 252 GFKPPVYLKAGDVVELGIDGLGTSRQEVIAF 282


>UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Roseiflexus|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Roseiflexus sp. RS-1
          Length = 288

 Score =  174 bits (423), Expect = 2e-42
 Identities = 91/213 (42%), Positives = 123/213 (57%), Gaps = 6/213 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V+C+G+NY  H  E      ++   PE P  F K   TV GP+D I L   V+  +  E+
Sbjct: 74  VICLGMNYVAHTIESYRARGREPKMPEYPVFFTKAAHTVCGPDDDIPLDPKVTNELDYEV 133

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL  +IGK    V    A +YV GYTI  DI A D +   +  Q   GK++   CP+GP 
Sbjct: 134 ELAFIIGKAGMNVPRDEAMEYVFGYTIVNDISARDLQSRHQ--QFFKGKSLYRACPMGPC 191

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           IVT+DEI NP  L ++  +NG  +Q S+T   I  IP II  LS  M L PG I+ TGTP
Sbjct: 192 IVTTDEIPNPAGLGIRLRLNGETRQDSHTGDLIFDIPAIIEHLSLGMPLEPGMIVATGTP 251

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            GVG+ R PPE+++PGDV+ +EI++IG    R+
Sbjct: 252 AGVGLGRTPPEYMRPGDVMEAEIDSIGILRNRI 284


>UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase
           precursor; n=3; Proteobacteria|Rep: Fumarylacetoacetate
           (FAA) hydrolase precursor - Polynucleobacter sp.
           QLW-P1DMWA-1
          Length = 349

 Score =  174 bits (423), Expect = 2e-42
 Identities = 89/215 (41%), Positives = 123/215 (57%), Gaps = 8/215 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508
           + CVG NY DH EE             P++P +F K   T+ GP D I     +S  +  
Sbjct: 135 IYCVGWNYLDHFEEGLKHRADTAVKEYPKVPVLFTKGTQTMNGPFDNIPYDAGISTMIDW 194

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E EL VVIGKK   +   +A DYV GY+   D  A D ++ ++  Q   GK++D   P+G
Sbjct: 195 EAELAVVIGKKGKNISEENAMDYVFGYSAYNDTTARDIQQKRQSGQWFKGKSLDGHGPMG 254

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           PW+VT+  + N  +  + CS+NGV+KQ ++  Q   KIP IIA LS  +TLLPGDII TG
Sbjct: 255 PWVVTAGGV-NLDDTRIICSVNGVEKQNASYKQMYFKIPAIIAELSRGLTLLPGDIIATG 313

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           TP GVG  R P EF++PGD++ + I  IG    ++
Sbjct: 314 TPSGVGAGRTPQEFMKPGDMMETNITGIGILRNKI 348


>UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Dinoroseobacter shibae DFL 12
          Length = 308

 Score =  173 bits (422), Expect = 3e-42
 Identities = 91/213 (42%), Positives = 123/213 (57%), Gaps = 6/213 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           + CVG NY +H  E       K+   E P  F K  + VVG    + +   VS+ +  E+
Sbjct: 94  IFCVGRNYAEHIAEGERAQNAKIGITEHPVYFTKPATAVVGHGGDVLIFPSVSEKIDYEV 153

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL VVIG     +    AF +V GYTI  DI A D ++     Q   GK++D  CPIGPW
Sbjct: 154 ELAVVIGTTGRDIPKDRAFAHVFGYTILNDITARDVQRRHG-GQYFKGKSLDGSCPIGPW 212

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           IVT+DEI +PQ+L++  S+NG  +Q   T+  I  IP +IA LS  +TL PGDII TGTP
Sbjct: 213 IVTADEITDPQDLSISLSVNGELRQNGWTHDMIFDIPTLIASLSEGLTLEPGDIIATGTP 272

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            GVG   +PP++L+PGD +  +I NIG  +  V
Sbjct: 273 SGVGYAMDPPQYLKPGDTVICDIANIGQLKNTV 305


>UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17;
           Staphylococcus|Rep: Uncharacterized protein SH1982 -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 301

 Score =  173 bits (421), Expect = 3e-42
 Identities = 87/209 (41%), Positives = 122/209 (58%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           + V+  G NY+DH  E       L ++F K  S++ G   TI    D++  +  E EL +
Sbjct: 93  NNVIAFGRNYQDHASELNHEVQRL-YVFTKAASSLTGDESTIPNHKDITDQLDYEGELGI 151

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK   K+  + A DY+ GYTI  DI  TD +   +  Q  L K++   CP+GP+IVT 
Sbjct: 152 VIGKSGEKIPKALALDYIYGYTIINDI--TDRKAQNEQDQAFLSKSLTGGCPMGPYIVTK 209

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DE+  P+N+N+   +N   +Q  NT+Q I+KI D+I  +S  + L PGDII TGTP GVG
Sbjct: 210 DELPTPENVNIVTKVNNDIRQDGNTSQMINKIDDLIEEISKYVALHPGDIIATGTPAGVG 269

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
               PP+FLQPGD +   I+NIGT  T +
Sbjct: 270 AGLQPPQFLQPGDEVKVTIDNIGTLTTYI 298


>UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=21; Firmicutes|Rep: Fumarylacetoacetate
           hydrolase family protein - Bacillus anthracis
          Length = 302

 Score =  172 bits (419), Expect = 6e-42
 Identities = 88/210 (41%), Positives = 123/210 (58%), Gaps = 2/210 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +LCVG NY++H  E       PE   IF K P+TV+G ++ I      +  +  E EL +
Sbjct: 95  ILCVGKNYREHAIEMGGVESIPENIMIFTKAPTTVIGMDEKINSHPHATNELDYEGELAI 154

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK+  ++    A ++V GYTI  DI A D ++  K  Q  LGK+ DTFCP+GP+++  
Sbjct: 155 VIGKRGKQIKKEKALEHVFGYTIINDITARDIQRKHK--QFFLGKSFDTFCPMGPYLIHK 212

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
             I  P  L+++  +NG  +Q SNTN+ I  I +II+ +S  MTL PGDII TGTP GVG
Sbjct: 213 SMISTPNALHIETIVNGEVRQTSNTNKMIFSIEEIISTISKGMTLEPGDIIATGTPAGVG 272

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40
               PP+FL  GD +   +E IGT    V+
Sbjct: 273 KGFTPPKFLHAGDEVVITVEGIGTLRNVVK 302


>UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=4; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Silicibacter sp. (strain TM1040)
          Length = 281

 Score =  172 bits (419), Expect = 6e-42
 Identities = 84/202 (41%), Positives = 121/202 (59%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K +C+GLNY DH  E  ++ PE P IF K  S + GPND +++    S     E+EL VV
Sbjct: 72  KFICIGLNYADHAAESGMSLPEEPVIFFKATSAICGPNDAVEIPR-TSVKTDWEVELGVV 130

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK A  +    A D+V GY +  D+   D++ ++   Q + GK+ DTF PIGPW+VT D
Sbjct: 131 IGKTAKYIGRDEALDHVAGYCVVNDLSERDFQLHRS-GQWVKGKSADTFGPIGPWLVTRD 189

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +PQNL +   +NG + Q  +T      +  +I+ LS  M+L PGD+I TGTP GVG+
Sbjct: 190 EVPDPQNLAMWLEVNGHRYQDGSTRTMHFDVATVISHLSQFMSLQPGDVISTGTPPGVGM 249

Query: 126 YRNPPEFLQPGDVITSEIENIG 61
            + P  +L+PGDV+   I  +G
Sbjct: 250 GQTPETYLKPGDVMELGIAGLG 271


>UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=13; Proteobacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Rhodopseudomonas palustris
          Length = 280

 Score =  171 bits (417), Expect = 1e-41
 Identities = 83/207 (40%), Positives = 123/207 (59%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V G  K + +GLNY DH  E  +  P  P +F K  +++ GPND ++ K   S  +  E+
Sbjct: 67  VGGAPKFIAIGLNYADHAAEANMPIPAEPIVFMKAINSLCGPNDDVE-KPRGSTKLDWEV 125

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL V+IG +A  V  + A +YV GY +  D+   +++  ++  Q   GK+ DTF P+GPW
Sbjct: 126 ELAVIIGTRAKYVTEADALNYVAGYAVCNDVSERNFQL-ERAGQWTKGKSHDTFGPLGPW 184

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           + T DEI +   L +   +NG ++Q  +T   I  +P I++ LS +MTL+PGDII TGTP
Sbjct: 185 VATKDEIADVHKLGMWLDVNGQRRQTGSTATMIFNVPKIVSYLSELMTLMPGDIITTGTP 244

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIG 61
            GVG    PP++L  GDV+T  IE +G
Sbjct: 245 PGVGTGMKPPQYLNVGDVVTLGIEGLG 271


>UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Parvibaculum lavamentivorans DS-1
          Length = 291

 Score =  171 bits (417), Expect = 1e-41
 Identities = 88/208 (42%), Positives = 116/208 (55%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KVL +GLNY+DH EE     PE    FNK  + + GP   I L   VS  +  E E+  V
Sbjct: 75  KVLAIGLNYRDHVEESGQPMPEHQVWFNKQHNCITGPYADIALP-SVSAFLDYEAEMCFV 133

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK+   V    A + + GY +  D+   DW+      Q+  GK+ DT  PIGPWIVT D
Sbjct: 134 IGKRCKHVPKERAHEVIAGYFVGDDVSVRDWQLRTNTWQI--GKSFDTHGPIGPWIVTPD 191

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+G+P  L++KC +NG  +Q SNT   I    D IA L+   TL  GD+I TGT GG+G 
Sbjct: 192 EVGDPHALDIKCWVNGELRQNSNTKHLIFDCFDQIAHLTQAFTLDIGDVIFTGTSGGIGA 251

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
              P + L+ GDV+  E+E +G  E RV
Sbjct: 252 AMKPMQLLKEGDVVRVEVEKLGYIENRV 279


>UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4;
           Euryarchaeota|Rep: Uncharacterized protein MJ1656 -
           Methanococcus jannaschii
          Length = 237

 Score =  171 bits (417), Expect = 1e-41
 Identities = 92/210 (43%), Positives = 126/210 (60%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNY DH +E  +  PE P IF K  S ++   D I ++  +SK V  E+EL +V
Sbjct: 39  KIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYI-IRPRISKRVDYEVELAIV 97

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGKK   +    A DY++GYTI  D+ A D ++  K  Q    K+ DTFCPIGP IV   
Sbjct: 98  IGKKCKNIKKDEANDYIMGYTILNDVTARDLQQ--KDGQWTRAKSFDTFCPIGPRIVKDI 155

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +   P NLN++C +NG  KQKSNT   I  + +++  ++++MTL PGDII TGTP GVG 
Sbjct: 156 D---PMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVGE 212

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37
                  L+ GDV+  EIE IG     V++
Sbjct: 213 -------LKAGDVVECEIEGIGILRNYVKD 235


>UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=8; Proteobacteria|Rep: Fumarylacetoacetate
           hydrolase family protein - Silicibacter pomeroyi
          Length = 305

 Score =  171 bits (416), Expect = 1e-41
 Identities = 82/210 (39%), Positives = 131/210 (62%), Gaps = 6/210 (2%)
 Frame = -3

Query: 654 VGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           +GLNY +H  E   +       P+ P +F+K P++V+   + I+    +++ +  E+EL 
Sbjct: 94  IGLNYVEHVAESAKSLDTSKELPKEPVVFSKPPTSVIASGEGIQHNAAMTQQLDWEVELA 153

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           V+IGK+A+++   +A  +V GY++  D+ A D   N++  Q +  K  DTFCP GP I+T
Sbjct: 154 VIIGKRATRIAKDNAMSHVFGYSVINDVSARD---NRRAGQWIFSKGQDTFCPFGPAIIT 210

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           +D++ +P NL++  + NGV+KQ+SNT   +  IP +IA +S+ +TL PGDII TGTP GV
Sbjct: 211 ADDVPDPHNLDLWLTKNGVEKQRSNTRHLLFDIPTLIADISSGITLEPGDIIATGTPAGV 270

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G  R+P E++ PGDVI   ++ IG     V
Sbjct: 271 GAGRDPQEWMWPGDVIECGVDGIGVLRNPV 300


>UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4;
           Thermoprotei|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Sulfolobus acidocaldarius
          Length = 307

 Score =  170 bits (413), Expect = 3e-41
 Identities = 91/214 (42%), Positives = 127/214 (59%), Gaps = 3/214 (1%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K+  + +NY+ H +E    PP+ P+IF KF +T++G N  + L    S  V  EIEL V
Sbjct: 95  EKIFLLAVNYRAHGQETNNNPPKEPYIFTKFNNTLIGHNQPV-LFPRASNKVDYEIELAV 153

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---QLLLGKAMDTFCPIGPWI 319
           ++GK+A  V+SS A DYV GYTI  DI   D +   +I    + + GK +DT  P+GPWI
Sbjct: 154 IMGKRAKYVNSSKALDYVFGYTIFNDISFRDKQFPPEIPYGMRWVHGKGLDTAAPMGPWI 213

Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
           VT DEI N  NL +K  +NG  +Q +     I K+  II  LSN +TL PGD+I TGTP 
Sbjct: 214 VTKDEIDNINNLRLKLRVNGEIRQDAYAEDMIFKVEQIIEYLSNGITLKPGDVISTGTPS 273

Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           GV +     ++L+PGDV+ +EI  IG     + E
Sbjct: 274 GVALATG--KYLKPGDVMEAEISKIGVLRNNLIE 305


>UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase
           family protein; n=2; Arthrobacter|Rep: Putative
           fumarylacetoacetate hydrolase family protein -
           Arthrobacter nitroguajacolicus
          Length = 299

 Score =  169 bits (411), Expect = 5e-41
 Identities = 89/208 (42%), Positives = 122/208 (58%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+C GLNY DH +E     P+ P +F K+  T+VG +D I +    S  V  E EL VV
Sbjct: 75  KVICCGLNYGDHIQEMGRALPDYPTLFAKYADTLVGASDPIYVHG--SDKVDWEAELAVV 132

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG    +VD   A   + GYT+A D+   DW+ N+ + Q   GKA D   P+GP ++T+D
Sbjct: 133 IGSNLYRVDEDQALAGIAGYTVANDVSMRDWQ-NRTL-QWFQGKAFDATTPLGPVMLTAD 190

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E   P + +V   +NG Q QK NT+  +     ++A +S    L PGD++LTGTPGGVG+
Sbjct: 191 EA--PADFDVYGYVNGEQVQKGNTSTLVFGPARLVAYISQFTMLRPGDVVLTGTPGGVGM 248

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
             NPP FL  GDV+T+EI  IG  E R+
Sbjct: 249 GMNPPRFLSDGDVLTTEIPGIGRLENRI 276


>UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;
           n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
           fumarylacetoacetate hydrolase - Aurantimonas sp.
           SI85-9A1
          Length = 293

 Score =  168 bits (409), Expect = 1e-40
 Identities = 89/218 (40%), Positives = 126/218 (57%), Gaps = 9/218 (4%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 511
           + CVG NY++H  E          K   P  P IF K  S ++GP  TI+  +D ++ V 
Sbjct: 78  IFCVGKNYREHASEFHNSGFDSGGKQAIPVAPVIFTKSLSAIIGPGATIEAGLDRTRTVD 137

Query: 510 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 331
            E EL VVIGK+A  V  + A DYV GY +  D+  T  E  +  SQ ++GK +DTF P+
Sbjct: 138 YEGELGVVIGKRAFGVTKADAMDYVFGYVVINDV--TSRELQRHHSQWVIGKGIDTFAPM 195

Query: 330 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151
           GP +VT+DE+ +   L V  ++NG  +QK++    I  IP +I  ++  MTLLPGDII T
Sbjct: 196 GPVLVTADEVPDVTKLTVTTTVNGETRQKASVAGLIFDIPTLIETMTATMTLLPGDIIAT 255

Query: 150 GTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           GTP GVG+  +PP +L  GD +   I+ +GT E  V +
Sbjct: 256 GTPAGVGIGFDPPRYLADGDRVAVTIDGLGTLENPVRQ 293


>UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Picrophilus torridus|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Picrophilus torridus
          Length = 281

 Score =  168 bits (409), Expect = 1e-40
 Identities = 91/209 (43%), Positives = 127/209 (60%), Gaps = 1/209 (0%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKMDVSKAVVCEIELT 493
           +K++CVG NYK+H  E     PE P +F+KF +T+ G  ND I   +D S ++  E EL 
Sbjct: 72  EKIICVGKNYKEHALETGSGIPESPVLFSKFNNTLTGHLNDII---IDFSDSIDYEGELG 128

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           +VIGKKA  VD + A DYV GY IA D+ A D +   + SQ LLGK  D F P GP+IVT
Sbjct: 129 IVIGKKARNVDENDAMDYVFGYYIANDVSARDLQY--RTSQWLLGKTPDGFYPNGPFIVT 186

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
            DE+ +P NL+++   NG   Q SNT   I  I  +I  +S  +TL+PGD+I TGTP GV
Sbjct: 187 KDEVNDPMNLDIRTLRNGDTVQHSNTRNMIFDIKYLIGYISKYLTLMPGDVISTGTPEGV 246

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETR 46
            +  N   +++  + I  +IE +G+ + R
Sbjct: 247 ILGTNEKNWIKNNETIEVKIEKLGSLKNR 275


>UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Rep:
           Blr5285 protein - Bradyrhizobium japonicum
          Length = 283

 Score =  167 bits (407), Expect = 2e-40
 Identities = 84/208 (40%), Positives = 122/208 (58%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNY+DH  E      E P +F +FP + VG    I +K  VS     E EL +V
Sbjct: 74  KIICVGLNYRDHVAETGRIVTEKPALFVRFPCSQVGHLQPI-VKPKVSDDFDYEGELALV 132

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK+   + ++ A D++ GY+   +    DW+++   SQ L GK        GPW+VT+D
Sbjct: 133 IGKEGRHIPANRALDHIAGYSCYNEGSVRDWQRHT--SQFLSGKTFAESGSFGPWLVTAD 190

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +P  L ++  +NG   Q + T+  I  IP +IA +S +  L+PGD+I+TGTPGGVG 
Sbjct: 191 EIPDPSKLTLQTRLNGTVVQDTTTDLLITAIPGLIAYISTICPLVPGDVIVTGTPGGVGA 250

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
            R PP +++PGD +  EI  IGT   +V
Sbjct: 251 KRTPPLWMRPGDTVEVEISGIGTLRNKV 278


>UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=4; Archaea|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Methanobacterium thermoautotrophicum
          Length = 260

 Score =  167 bits (407), Expect = 2e-40
 Identities = 87/209 (41%), Positives = 127/209 (60%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+CVGLNY+DH  E  +  P+ P IF K P+TV+G  DT+ +  ++S  V  E+EL  V
Sbjct: 59  KVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTV-IYPEMSSEVDYEVELAAV 117

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           + ++A +VDSS A +++ GYT+  D+ A D ++     Q    K+ DTFCPIGP I T  
Sbjct: 118 VSERARRVDSSAASEFIAGYTVLNDVTARDLQRRD--GQWTRAKSFDTFCPIGPVIETDV 175

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
               P NL++   +NG  +Q SNT+  I  + +++  +S+VMTL PGD+I TGTP GVG 
Sbjct: 176 ---TPDNLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEPGDVIATGTPPGVGQ 232

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
                  + PGD + + +E +GT   RVE
Sbjct: 233 -------MVPGDTVRATVEGVGTLVNRVE 254


>UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Alkaliphilus metalliredigens
           QYMF|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Alkaliphilus metalliredigens QYMF
          Length = 298

 Score =  167 bits (406), Expect = 2e-40
 Identities = 82/207 (39%), Positives = 121/207 (58%), Gaps = 6/207 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V+C+GLNYK H  E +      +  PE P  F K  +  +GP + I     +++ V  E+
Sbjct: 87  VICLGLNYKAHVAESQSALSAGIKMPEFPVYFTKMSTQAIGPQEAINSHPQITQEVDYEV 146

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL V+IGK  + +      D++ GYTI  D+ A D ++    +Q + GK++DTF  +GPW
Sbjct: 147 ELAVIIGKGGTNIPPEEVQDHIFGYTILNDVSARDLQRRH--NQWVKGKSLDTFTVMGPW 204

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           I+  + I  P  L++   +NG  +Q SNT  FI  IP +I+ LS  +TL  GD+I TGTP
Sbjct: 205 IMEKETISLPVELDLYSKVNGEIRQHSNTKDFIFDIPTVISELSKGLTLEAGDVIATGTP 264

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIG 61
            GVG+  NPP++L+ GDV+   IE IG
Sbjct: 265 AGVGMGFNPPKYLKAGDVVECYIEKIG 291


>UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctional
           decarboxylase/isomerase; n=4; Pezizomycotina|Rep:
           Function: E. coli hpaG is a bifunctional
           decarboxylase/isomerase - Aspergillus niger
          Length = 358

 Score =  167 bits (405), Expect = 3e-40
 Identities = 90/211 (42%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           V+C+GLNYK H +E  L  P  P +F K    + GP +TI +  D    +  E ELTVVI
Sbjct: 64  VICIGLNYKQHAKEASLDVPTYPPVFTKPADVLAGPFETIPIHRDAQSHLDYEGELTVVI 123

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI-SQLLLGKAMDTFCPIGPWIVTSD 307
           GK A  V +  A DYVLGYT   D+ A +++  +    Q    K+ D F PIG  +V++ 
Sbjct: 124 GKDAKNVSAEDALDYVLGYTAGNDLSARNFQMPEASGGQFCYAKSFDKFAPIGHVLVSAQ 183

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +PQ L++   +NGV KQ +NT+  I  + DI++ LS  MTL  G +I+TGTP GVG 
Sbjct: 184 EVQDPQQLSLVTKVNGVVKQTTNTSDMIWGVRDIVSHLSRGMTLRKGTLIMTGTPSGVGF 243

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34
           +R   EFLQ GDV+  E+E +G  E  V +F
Sbjct: 244 FRK--EFLQDGDVV--EVE-LGVREPGVIDF 269


>UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=5; Thermoprotei|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Pyrobaculum islandicum (strain DSM 4184 / JCM 9189)
          Length = 310

 Score =  166 bits (403), Expect = 5e-40
 Identities = 83/217 (38%), Positives = 128/217 (58%), Gaps = 6/217 (2%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K+LCV +NY++H  E  + PP+ P+ F KFP+ +VG    + +K  V + +  E+EL V
Sbjct: 96  EKILCVAVNYREHGAETGIEPPDKPYFFPKFPNALVGHEGYV-VKHRVVQKLDWEVELVV 154

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQL----LLGKAMDTFCPIG 328
           V+G+    ++   A DYV GYT+  D+   DW+    K   Q     + GK MDT  P+G
Sbjct: 155 VMGRPGKYIEPERALDYVFGYTVGLDMSMRDWQNPDEKTARQYGKNWIWGKTMDTAAPVG 214

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           P+I T DE+ +P  L ++  +NG  +Q+ NT+Q I  I  +I   S  +TL PGD+I TG
Sbjct: 215 PYIATRDEVPDPNRLGLRLWVNGQLEQEGNTSQLIFNIQQLIYWASQGITLRPGDLIFTG 274

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           TP GVG  +   +FL+ GD++ +E+E+IG     + E
Sbjct: 275 TPPGVGWAKG--KFLKGGDIVEAEVESIGRLRAYIIE 309


>UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1;
           Clostridium kluyveri DSM 555|Rep: Putative
           uncharacterized protein - Clostridium kluyveri DSM 555
          Length = 301

 Score =  165 bits (401), Expect = 9e-40
 Identities = 91/213 (42%), Positives = 122/213 (57%), Gaps = 6/213 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V C+G NY++H  E KLT       P++P  F K  S  +G  D+I+   +V+  V  E+
Sbjct: 86  VFCLGKNYEEHAREIKLTRITGNEIPKVPIYFTKVASPAIGNGDSIEFSSEVTNQVDYEV 145

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL VVIGK    +    A  Y+ GYTI  DI A D + +    Q   GK++DTFCP+GP 
Sbjct: 146 ELGVVIGKNGKNIKKEEAEKYIFGYTIINDISARDLQGSH--IQWFKGKSLDTFCPMGPC 203

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           IV  +EI  P NL++KC +N   +Q SNT   I  IP II+ LS  ++L  GDII TGTP
Sbjct: 204 IVHKNEIPFPINLDIKCWVNEELRQDSNTKNLIFDIPYIISDLSKGVSLKAGDIIATGTP 263

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            GVG+  +P + L+ GD I   IE IG+    V
Sbjct: 264 SGVGMGFSPIKVLKQGDSIECYIEKIGSLVNNV 296


>UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Polynucleobacter sp.
           QLW-P1DMWA-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 299

 Score =  165 bits (401), Expect = 9e-40
 Identities = 80/205 (39%), Positives = 122/205 (59%), Gaps = 3/205 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM-DVSKAVVCEIELTV 490
           K++CVGLNY+ H +E  +  P +P +FNK+ +++   N  +++    VS  +  E EL +
Sbjct: 88  KIVCVGLNYRAHADEVGMVHPRVPPLFNKYNNSLAAHNCLLQIPPPSVSYKLDYETELLI 147

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK+   V  S A DYV GY  + D  + D +      Q ++GK +D + PIGP+ VT 
Sbjct: 148 VIGKQMRNVPESAALDYVAGYCTSNDFSSRDLQLELPSGQWMIGKTLDQYAPIGPYFVTG 207

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV- 133
           D +GNP NL VK  +NG  +Q SNT+ FIH    +++ +S    L PGDI+ TGTP GV 
Sbjct: 208 DLVGNPNNLQVKTWVNGELRQNSNTSDFIHNTQKMLSYISTYWALEPGDIVFTGTPQGVI 267

Query: 132 -GVYRNPPEFLQPGDVITSEIENIG 61
            G+ ++   +L+ GD + S +E +G
Sbjct: 268 AGMPKDKQVWLKKGDKVVSSVEKLG 292


>UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Acidovorax sp. (strain JS42)
          Length = 281

 Score =  165 bits (400), Expect = 1e-39
 Identities = 82/208 (39%), Positives = 120/208 (57%), Gaps = 1/208 (0%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V G  K++CVGLNY DH  E  L  P  P +F K  S + GP D +++     K    E+
Sbjct: 67  VGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPPGALKTD-WEV 125

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL +VIG +  +V  + A  +V GY +A D+    ++  +   Q   GK  DTF P+GPW
Sbjct: 126 ELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERG-GQWDKGKGCDTFAPVGPW 184

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           +VT+DEI +P  + +   +NG + Q  +T  FI  +P ++A +S  MTL PGD++LTGTP
Sbjct: 185 LVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLEPGDLVLTGTP 244

Query: 141 GGVGVYRNP-PEFLQPGDVITSEIENIG 61
            GVG+ + P P FL+ GDV+      +G
Sbjct: 245 AGVGLGQKPTPRFLRAGDVMRLGATGLG 272


>UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=2; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 287

 Score =  164 bits (399), Expect = 2e-39
 Identities = 86/214 (40%), Positives = 117/214 (54%), Gaps = 8/214 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508
           + CVG NY  H +E            P   P +F K P  VVGP D + L   VS+ +  
Sbjct: 75  IFCVGRNYHAHAKELSASVFKDNSANPASWPIVFTKVPECVVGPTDDVMLPTGVSEEIDY 134

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E EL +VIG     +  + A  +V GYTI  D+ A D +   +  Q  LGK+ DTFCP+G
Sbjct: 135 ESELAIVIGTGGRNISRAAAMQHVFGYTIINDVTARDVQMRHQ--QWDLGKSFDTFCPMG 192

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           PWIVT+DE+   +   V+  +NG  +Q + T   I  IP +I   S  +TL PGD+I TG
Sbjct: 193 PWIVTADELDGSRT-RVRGWVNGELRQDAQTTDLIFDIPALIETCSRGITLYPGDVIATG 251

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 46
           T  GVG+   PP++L+ GDV+  EI+ IG  E R
Sbjct: 252 TAAGVGMGMKPPQYLKAGDVVRIEIDGIGAIENR 285


>UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Saccharopolyspora erythraea NRRL
           2338|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Saccharopolyspora erythraea (strain
           NRRL 23338)
          Length = 233

 Score =  164 bits (399), Expect = 2e-39
 Identities = 86/198 (43%), Positives = 116/198 (58%)
 Frame = -3

Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475
           V LNY D   E     P +PF+F K  S+V+G  D I +   V++ V  E EL VVIG +
Sbjct: 19  VALNYVDSIAEMGFERPTVPFLFPKLSSSVIGDGDPIVVDTTVTRFVDWETELAVVIGTE 78

Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 295
           A  V ++ A + V GYT+A DI A D        Q L GK +DTFCP+G  +V + EI +
Sbjct: 79  ARNVPAAEALEVVYGYTVANDISARDLLTAD--GQWLRGKGLDTFCPLGHVVVPAAEIPD 136

Query: 294 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115
           PQ L V+  +NG   Q   T   +  + ++I+ LS   TL PGD+ILTGTP G G + +P
Sbjct: 137 PQALAVRTWLNGEIVQDGTTADMVFGVGELISYLSRFFTLRPGDVILTGTPAGCGAFMDP 196

Query: 114 PEFLQPGDVITSEIENIG 61
           P  L+PGDV+ SE+E IG
Sbjct: 197 PRGLRPGDVVESEVEGIG 214


>UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4;
           Thermococcaceae|Rep: Uncharacterized protein PH0643 -
           Pyrococcus horikoshii
          Length = 230

 Score =  164 bits (399), Expect = 2e-39
 Identities = 94/207 (45%), Positives = 123/207 (59%), Gaps = 2/207 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ +  NY +H  E    PPE P IF K PS ++GP  +I L    SK V  E+EL V+
Sbjct: 22  KIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSIILPRR-SKRVDHEVELAVI 80

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 313
           +GK+A  V +S AFDY+LGYTI  DI A D   E  KK     + K  DTF PIGP +V 
Sbjct: 81  MGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISKGFDTFAPIGPRVVD 140

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           S E+ +P +L +   +NG  +Q   T+Q I KIP++I  +S++MTL PGDII TGTP GV
Sbjct: 141 SREL-DPSDLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLEPGDIIATGTPPGV 199

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFE 52
           G  R+       GD I + IE IG  E
Sbjct: 200 GPLRH-------GDRIEAWIEGIGKME 219


>UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase (HHDD isomerase)/5-
           carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase;
           n=1; Frankia alni ACN14a|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD
           isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate
           decarboxylase - Frankia alni (strain ACN14a)
          Length = 276

 Score =  163 bits (396), Expect = 4e-39
 Identities = 83/208 (39%), Positives = 121/208 (58%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+GLNY  H +E   TPP  P +F K+   ++GP D I L   V++AV  E EL  V
Sbjct: 69  KIICMGLNYATHLKEMGRTPPTHPTLFAKYTRALIGPTDDI-LVPPVTEAVDWEGELAFV 127

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG      D + A + + GYTI  D+   DW+   +  Q L GK+ +   P+GP +VT D
Sbjct: 128 IGTTVRFADEAAAREAIAGYTIMNDVTMRDWQF--RTLQFLQGKSFEGSTPLGPALVTPD 185

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ NP +L ++  +NG   QKS T+  +    +I+  +S  +TL PGD++ TGTPGGVG 
Sbjct: 186 ELDNPADLALRTLVNGEVMQKSRTSDLLFPPVEIVRYVSQFITLEPGDVLTTGTPGGVGH 245

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
            RNP  +L  GDV+T ++E +G     V
Sbjct: 246 GRNPKVYLADGDVVTVDVEGLGVVRNTV 273


>UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Candidatus Nitrosopumilus
           maritimus SCM1|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Candidatus Nitrosopumilus maritimus
           SCM1
          Length = 289

 Score =  163 bits (395), Expect = 5e-39
 Identities = 85/210 (40%), Positives = 120/210 (57%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K++C+  NY DH +EQ LT PE P I  K  + + G N  I+   D    +  E+EL +
Sbjct: 78  NKIICLAFNYVDHAKEQGLTAPEDPAIVIKPRTALNGNNANIECP-DFVTQLDYEVELAL 136

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           +IGK    +    A + V GY +  D+ A D +   K  Q   GK+ D+F P GPWI T+
Sbjct: 137 IIGKNCKNISVEEAQNVVFGYMVFNDVSARDIQFKDK--QFTRGKSFDSFAPCGPWITTA 194

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI  PQNL +   ING  +Q S+T+    KIP+II+++S VMTL  GDII TGTP GV 
Sbjct: 195 DEIQEPQNLKLTTKINGELRQNSSTSNMFIKIPEIISKISKVMTLEKGDIISTGTPAGVM 254

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40
           + +    FL+ GD +  EIE +G     ++
Sbjct: 255 LNKPNAIFLKDGDKVEMEIEGLGVLNNTIK 284


>UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila
           melanogaster|Rep: CG11251-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 338

 Score =  162 bits (394), Expect = 6e-39
 Identities = 87/208 (41%), Positives = 122/208 (58%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ V  NY D+C+EQ ++ P  P    KF S++ G  D I+     +K +    +L VV
Sbjct: 133 KIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSS-AKHIDYGCQLAVV 191

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +GK+  +V    A ++V G+ + QDI A DW         L G +MDTF P+GP IV   
Sbjct: 192 MGKRCREVSPKEALNHVFGFMVVQDIVARDWNVP------LGGHSMDTFLPLGPTIVHRC 245

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
            + +  NL +K  ING ++Q  NT   I KI  +I RLS  +TL PGDIILTGTP G G 
Sbjct: 246 HVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIILTGTPAGSGA 305

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
           +R+P  FL+PGD+I SEI+N+G    +V
Sbjct: 306 FRHPSCFLKPGDLIESEIQNLGKMCNKV 333


>UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase;
           n=1; Psychroflexus torquis ATCC 700755|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic
           acid hydratase - Psychroflexus torquis ATCC 700755
          Length = 251

 Score =  162 bits (393), Expect = 8e-39
 Identities = 82/179 (45%), Positives = 111/179 (62%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNY  H +E  +  P  P +F K  S +VGP D I L     K+   E+EL ++
Sbjct: 75  KIVCVGLNYAKHAKESGMEVPTEPVLFFKASSAIVGPYDDIILPKKSEKSD-WEVELAII 133

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG KAS V  S A D+V GY I  DI   +++  +   Q + GK+ DTF PIGP++VT+D
Sbjct: 134 IGDKASYVKESEAMDHVAGYVIHNDISEREYQLERS-GQWVKGKSCDTFAPIGPFMVTTD 192

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           EI +P NL +   +NG   Q SNT+  I  IP +++ +S  MTLLPGD+I TGTP GVG
Sbjct: 193 EIDDPHNLRLWLKLNGETMQDSNTSDLIFGIPKLVSYISTYMTLLPGDVISTGTPFGVG 251


>UniRef50_O53242 Cluster: POSSIBLE
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE; n=41;
           Bacteria|Rep: POSSIBLE
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE -
           Mycobacterium tuberculosis
          Length = 239

 Score =  161 bits (392), Expect = 1e-38
 Identities = 89/208 (42%), Positives = 120/208 (57%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+CVG NY DH  E    PP  P IF K  + ++GPN  I+L  + S  V  E EL +V
Sbjct: 36  KVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPANASP-VHFEGELAIV 94

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+    V ++ A D +LGYTI  D+ A D +++    Q    K  DTFCP+GPWIVT  
Sbjct: 95  IGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSD--GQWTRAKGHDTFCPVGPWIVTDL 152

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
              +P +L ++  +NG  KQ + T+  IH I  I+  +S +MTLLPGD+ILTGTP GVG 
Sbjct: 153 APFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGVGP 212

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                  ++ GD ++  IE IGT    V
Sbjct: 213 -------IEDGDTVSITIEGIGTLTNPV 233


>UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp.
           RHA1|Rep: Probable hydrolase - Rhodococcus sp. (strain
           RHA1)
          Length = 553

 Score =  161 bits (392), Expect = 1e-38
 Identities = 85/219 (38%), Positives = 126/219 (57%), Gaps = 12/219 (5%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP------------PELPFIFNKFPSTVVGPNDTIKLKMDVSK 520
           V CVG NY +H  E   +             P+ P +F K  +TV+   D +    D++ 
Sbjct: 73  VFCVGRNYSEHAAEFAESGFDATGSADGQHVPQYPVVFTKPAATVIACGDPVDPHTDITS 132

Query: 519 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 340
           A+  E E+ ++IGK+ASKV    A DYV GYT+  D+ A D +++ K  Q  +GK++DTF
Sbjct: 133 ALDYEGEIGIIIGKRASKVSRDDAMDYVWGYTLINDVTARDLQRDHK--QWFIGKSLDTF 190

Query: 339 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 160
           CP+GPW VT+DEI +  +L ++  +NG  +Q +NT Q I  +P II  LS  +TL PGD+
Sbjct: 191 CPLGPWAVTADEI-DINDLQLQTRVNGELRQDTNTAQLIFDVPTIIETLSAGITLEPGDV 249

Query: 159 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           I TGTP GVG+  +PP++L  GD +      +G     +
Sbjct: 250 IATGTPVGVGIGFDPPKYLVEGDEVIVSAPGLGELRNTI 288


>UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 286

 Score =  161 bits (392), Expect = 1e-38
 Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 2/210 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           +LCVGLNY+ H EE  L  PE P IF K    + GP + + +  D    +  E ELT+VI
Sbjct: 70  ILCVGLNYRRHAEECNLQIPENPAIFMKPSDALAGPLEDVPIHKDCQSMLDYEGELTIVI 129

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVTS 310
           GK    V +++  DYVLGYT+  D+ A +++    +S  Q    K+ D FCPIGP I ++
Sbjct: 130 GKDCKNVSAANFQDYVLGYTVGNDVSARNYQLPANVSGGQFGYAKSFDKFCPIGPCIAST 189

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
             I +PQ L     +NG ++Q++ T+  I+ I  +I  LS   TL  G  ILTGTP GVG
Sbjct: 190 KVIPDPQKLTYWTKVNGEKRQETGTDDMIYTIGQVIEHLSRGTTLRAGTAILTGTPSGVG 249

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40
           ++  P  FL+ GD +   ++ IG+   +++
Sbjct: 250 LFMEPKNFLKDGDEVEIYVDGIGSIINKMK 279


>UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=5; Pezizomycotina|Rep: Fumarylacetoacetate
           hydrolase family protein - Neosartorya fischeri (strain
           ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
           fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 289

 Score =  161 bits (392), Expect = 1e-38
 Identities = 82/209 (39%), Positives = 117/209 (55%), Gaps = 2/209 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM--DVSKAVVCEIELTV 490
           V C+GLNY+ H  E  L  P+ P +F K  +++ GP D I +       + +  E EL +
Sbjct: 72  VRCLGLNYEQHARESNLPIPKYPVLFYKPVTSIAGPRDDIPISTMAQEGEGLDYECELVI 131

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK+A  V  S A DYVLGY +  D+   DW+  +   Q  LGK  D + P GP IV+S
Sbjct: 132 VIGKEAKDVPESRALDYVLGYAVGNDVSHRDWQIKRGGGQWGLGKGFDGWAPFGPGIVSS 191

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
             I +P  L++   +NG   Q S+T   I  +  ++A LS   TLLPGD+I TGTP GVG
Sbjct: 192 RLIRDPNALHISTRLNGQVVQSSSTKDMIFSVAKVVAFLSQGTTLLPGDLIFTGTPQGVG 251

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
           + R P  +L+ GD +   +E +G+   +V
Sbjct: 252 MGRKPALWLKDGDQVEVSLEGVGSCVNQV 280


>UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep:
           Bll6360 protein - Bradyrhizobium japonicum
          Length = 314

 Score =  161 bits (391), Expect = 1e-38
 Identities = 82/209 (39%), Positives = 121/209 (57%), Gaps = 1/209 (0%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V G  K + +GLNY DH  E  L  P  P +F K  +++ GPND + L     K    E+
Sbjct: 93  VSGVGKFVAIGLNYADHAAEAGLPLPSEPIVFQKAITSLSGPNDAVVLPRGSLKGD-WEV 151

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL +VIG +AS V+   A  YV GY +  D+   +++  +       GK  DTF P+GPW
Sbjct: 152 ELGIVIGSRASYVEPVEALQYVAGYCVVNDVSEREYQMERG-GTWDKGKGCDTFGPVGPW 210

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           +VT+DE+ +P  L++   +NG + Q+ NT   +     I++ +S  MTL+PGDII TGTP
Sbjct: 211 LVTTDEVPDPGRLDIWLELNGRRMQQGNTRTMVFGCAGIVSYVSQFMTLMPGDIIATGTP 270

Query: 141 GGVGVYRNP-PEFLQPGDVITSEIENIGT 58
            GVG+   P P +L+ GD++T  I+ +GT
Sbjct: 271 PGVGMGMKPDPIYLKVGDIMTLGIQGLGT 299


>UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;
           n=2; Rhodococcus|Rep: Possible fumarylacetoacetate
           hydrolase - Rhodococcus sp. (strain RHA1)
          Length = 296

 Score =  161 bits (391), Expect = 1e-38
 Identities = 79/203 (38%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           ++  +G+NY DH EE  LT P+ PF+F KFP+++ GP DTI+        V  E+EL  V
Sbjct: 72  QIFAIGVNYADHVEESGLTLPDAPFVFTKFPASITGPYDTIE---HPGGLVDFEVELVAV 128

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFCPIGPWIVTS 310
           IGK+A  V  +  ++YV G T+ QD+   D +       Q  LGK+   F PIGP +VT 
Sbjct: 129 IGKEARHVPVAEGWEYVAGLTLGQDLSERDLQLSGPPPQQFTLGKSFAGFAPIGPVLVTP 188

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DE  +P ++ V   ++G   Q S T   I  IP +++ LS+++ L PGD+I TGTP G+G
Sbjct: 189 DEFADPDDIEVSTILSGELMQNSRTRHLIFPIPVLVSYLSSILPLRPGDLIFTGTPSGIG 248

Query: 129 VYRNPPEFLQPGDVITSEIENIG 61
             R+P   +   D + S  + IG
Sbjct: 249 FTRDPKRLIGVDDELVSRADTIG 271


>UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase;
           n=8; Pezizomycotina|Rep: Predicted fumarylacetoacetate
           hydralase - Aspergillus oryzae
          Length = 289

 Score =  161 bits (391), Expect = 1e-38
 Identities = 84/210 (40%), Positives = 116/210 (55%), Gaps = 3/210 (1%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI---KLKMDVSKAVVCEIELT 493
           V C+GLNY+ H  E  L  P+ P +F K  + + GP D I    +  DV + +  E EL 
Sbjct: 72  VRCLGLNYEQHARESNLPIPKYPVLFYKPITAITGPYDDIPICSMAQDV-EGLDYECELV 130

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           +VIGK+A  +    A DYVLGY +  DI   DW+  +   Q  LGK  D + P GP IV+
Sbjct: 131 LVIGKQAKNIPEEQALDYVLGYAVGNDISHRDWQLKRGGGQWGLGKGFDGWAPFGPGIVS 190

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           +  I NP  LN+   +NG   Q S+T   I  +   ++ LS   TLLPGD+I TGTP GV
Sbjct: 191 TKLIRNPNALNISTKVNGQTVQSSSTKDMIFGVAQTVSFLSQGTTLLPGDLIFTGTPQGV 250

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G+ R P  +L  GD +   +E++G+   RV
Sbjct: 251 GMGRKPAAWLTNGDQVEVSLEDVGSCVNRV 280


>UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3;
           Burkholderiales|Rep: Putative hydrolase - Bordetella
           bronchiseptica (Alcaligenes bronchisepticus)
          Length = 304

 Score =  160 bits (389), Expect = 3e-38
 Identities = 84/214 (39%), Positives = 120/214 (56%), Gaps = 7/214 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP-------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505
           V CVG NY++H  E  L         PE    F K P+ V+G    +K    ++ ++  E
Sbjct: 91  VFCVGRNYREHIIEGNLARGRPANSFPEAIEFFTKAPTAVIGHGGHVKRHAGLTDSLDYE 150

Query: 504 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 325
           +EL +VIG+  + +    A D+V GYTI  DI A D +      Q   GK++DT CP+GP
Sbjct: 151 VELAIVIGRAGADIPREKALDHVFGYTIVNDITARDLQARH--GQWFKGKSLDTSCPMGP 208

Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
            +V    I +  NL V  S+NG  +Q+ NT+  I  +  ++A+LS  MTLLPGD+I TGT
Sbjct: 209 VVVHRSAIPDANNLAVSLSVNGELRQQDNTSDMIFDVAAVVAQLSAGMTLLPGDVIATGT 268

Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           P GVG    PP  LQ GDV+++ +E+IGT    +
Sbjct: 269 PKGVGFALTPPRCLQVGDVVSASVEHIGTLTNEI 302


>UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium
           difficile|Rep: Putative hydrolase - Clostridium
           difficile (strain 630)
          Length = 294

 Score =  160 bits (388), Expect = 3e-38
 Identities = 83/214 (38%), Positives = 122/214 (57%), Gaps = 6/214 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           ++C+GLNYKDH  E      + +  P+ P  F+K    ++G +D I L  D+ + +  E 
Sbjct: 83  IICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYES 142

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL V+IGK+   +    A++Y+ GYTI  DI  ++     K  Q   GK++DT   +GP 
Sbjct: 143 ELAVIIGKEGINISKEDAYEYIFGYTIVNDI--SERALQDKHVQWFRGKSLDTHTSMGPC 200

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           IV  +E  +P  L++   +NG  +Q SNT  FI  IP II  LS  MTL PGDII TGTP
Sbjct: 201 IVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTP 260

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
            GV +  NP  +L+ GD++  ++E IG  +  V+
Sbjct: 261 AGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD 294


>UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 274

 Score =  158 bits (384), Expect = 1e-37
 Identities = 81/204 (39%), Positives = 121/204 (59%), Gaps = 2/204 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVV 487
           V C+GLNYK+H  E K+T P+ P +F K  + +    + I L   V       E+EL ++
Sbjct: 65  VRCIGLNYKEHAAEMKMTLPDAPTVFLKANTCISSAAEPIVLPSVVDHDEADYEVELAII 124

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++   V  + A  YVLGY++A D+ A   +   K SQ    K MD FCP+GP IV+++
Sbjct: 125 IGQRCKNVSVAEAMGYVLGYSVANDVTAR--KHQGKTSQWSYAKGMDGFCPLGPCIVSAE 182

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +I +P    ++ S+NG   Q ++ +  I  I ++++ LS   TLLPG +I+TGTP G+GV
Sbjct: 183 KIPDPSVFQLRTSLNGKTMQNASADDMIFSIAEVVSYLSQGHTLLPGTVIITGTPCGIGV 242

Query: 126 YRNPPEFLQPGDVI-TSEIENIGT 58
            +NPP FL+PGD +  S    IGT
Sbjct: 243 SQNPPVFLKPGDRLRISASHGIGT 266


>UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2;
           Bordetella|Rep: Putative uncharacterized protein -
           Bordetella parapertussis
          Length = 294

 Score =  157 bits (382), Expect = 2e-37
 Identities = 85/217 (39%), Positives = 118/217 (54%), Gaps = 10/217 (4%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP----------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 514
           V CVG NY +H  E   +           P  P IF+K PS+V GP D I   +D   +V
Sbjct: 79  VFCVGKNYHEHAREFARSGFDSSAAAGAVPAAPIIFSKPPSSVSGPGDAIDTALDPCDSV 138

Query: 513 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 334
             E EL VVIGK          + +V GYT+  D+  T     K+ SQ LLGK +D +CP
Sbjct: 139 DYEAELAVVIGKAGRVAPDDDPWSFVFGYTLVNDV--TSRGLQKRHSQWLLGKGIDGYCP 196

Query: 333 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 154
           +GP +V++DEIG+   L + C +NG  +Q +  +  I  IP ++  +   +TL PGD+I 
Sbjct: 197 MGPALVSADEIGDIGALEITCEVNGELRQSARLSDLIFDIPTLVRAIGASITLQPGDVIA 256

Query: 153 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           TGTP GVG+   PP++L+ GDV+    E IG  E  V
Sbjct: 257 TGTPVGVGIGFTPPKYLRRGDVVRVRAEPIGVLENPV 293


>UniRef50_Q67K64 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Symbiobacterium thermophilum|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Symbiobacterium thermophilum
          Length = 254

 Score =  157 bits (381), Expect = 2e-37
 Identities = 84/208 (40%), Positives = 117/208 (56%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+G NY+DH  E     PE P  F K PS ++GP + I+L  D    V  E EL VV
Sbjct: 56  KIVCIGRNYRDHAAELGNAAPERPMFFLKAPSALIGPGEAIRLP-DPDATVHWEAELAVV 114

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++   V  + A  YV GYTIA D+   D +K         GK+ DTFCP GP +VT  
Sbjct: 115 IGRRMKDVAPADALSYVFGYTIANDVSHRDAQKADGAFGFGRGKSYDTFCPCGPAVVT-- 172

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E  +P +  +  + N   +Q  +T   IH +P++++ LS +MTL+PGD++LTGTP GVG 
Sbjct: 173 EGIDPADALITLTCNEEVRQSDSTGLMIHPVPELLSYLSQIMTLMPGDLVLTGTPKGVGA 232

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                  ++PGD+I   I  IGT    V
Sbjct: 233 -------MKPGDLIEIHIPGIGTLANPV 253


>UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=5; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 284

 Score =  157 bits (380), Expect = 3e-37
 Identities = 76/203 (37%), Positives = 118/203 (58%), Gaps = 1/203 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKL-TPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           + + +GLNY++H  E     P +LP +F KF S++ GP   + L          E+E+  
Sbjct: 77  QAIAIGLNYEEHAHETGYQVPTQLPPVFAKFASSITGPRGLVDLPP--GGHTDWEVEVVA 134

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIG+ A ++    A+ +V G T+ QD+     +      Q  L K+   F P+GPW+VT 
Sbjct: 135 VIGRTAHRISPDEAWGHVAGLTVGQDLSERISQMAGPAPQFGLAKSFPGFSPMGPWLVTP 194

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           +E+ +P +L + C+I+G   Q   T++ I  IP  IA LS V+TLLPGD++ TGTP GVG
Sbjct: 195 EELADPDDLALGCAIDGETVQDGRTSKLIFSIPRSIAALSQVLTLLPGDVVFTGTPDGVG 254

Query: 129 VYRNPPEFLQPGDVITSEIENIG 61
           + R+P  FL+PG+ + + +E IG
Sbjct: 255 LGRSPQRFLRPGETLRTWVEGIG 277


>UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Clostridiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Alkaliphilus metalliredigens QYMF
          Length = 300

 Score =  156 bits (378), Expect = 5e-37
 Identities = 80/214 (37%), Positives = 124/214 (57%), Gaps = 6/214 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKL---TPPELPF---IFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V+CVGLNY +H +E K       E+P     F+K  + V GP + I+    +++++  E+
Sbjct: 89  VICVGLNYAEHIDETKKGFDENMEIPLHTVYFSKRANQVKGPGEEIESHSHLNESMDYEV 148

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL V+IGK+   +    A +Y+ GYTI  D+ A   +KN    Q   GK++D F  +GP 
Sbjct: 149 ELAVIIGKEGINISKEEAKEYIFGYTILNDLSARGLQKNHV--QWFRGKSLDGFTSMGPC 206

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           IV    +G P  L++K  +N   +Q SNT   +  +  II+ +S  MTLLPGD+I TGTP
Sbjct: 207 IVHGSSVGFPLELDIKSRVNDELRQNSNTKFMMKDVSTIISEISQGMTLLPGDVIATGTP 266

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
            GVG+   PP FL+ GD +  EI+++G  + +++
Sbjct: 267 SGVGMGFTPPRFLKAGDTVECEIQHMGLLKNKIK 300


>UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=3; Alphaproteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Roseobacter sp. MED193
          Length = 285

 Score =  156 bits (378), Expect = 5e-37
 Identities = 77/201 (38%), Positives = 108/201 (53%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           + CVGLNY DH  E  L  PE P +FNK   T  GPND I     +SK +  E+EL +VI
Sbjct: 75  IWCVGLNYSDHAAEAGLPVPEEPILFNKSTVTYCGPNDDILKSAQMSK-LDWEVELGIVI 133

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304
            K A  +    A D++ G+ +  DI    W+  +   Q + GK+   FCP GP + T +E
Sbjct: 134 SKPALNISRDQAMDHIAGFVLVNDISERAWQMERS-GQWVKGKSFPNFCPTGPVLATKEE 192

Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124
             + QNL +   +NG + Q  NT   I  +  I++ +S    L PGD+I TGTP GVG  
Sbjct: 193 FADVQNLGMWLDVNGERMQTGNTGTMIFDVATIVSYMSEFTRLEPGDLICTGTPPGVGAG 252

Query: 123 RNPPEFLQPGDVITSEIENIG 61
             PP +L  GD ++  I+ +G
Sbjct: 253 MTPPVWLNEGDKVSLGIDGLG 273


>UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Exiguobacterium sibiricum
           255-15|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Exiguobacterium sibiricum 255-15
          Length = 277

 Score =  155 bits (377), Expect = 7e-37
 Identities = 80/210 (38%), Positives = 117/210 (55%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           V+CVG NY DH +E          +F K PS++VGP + I+   D+++ +  E EL ++I
Sbjct: 70  VICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFEAIERHADLTQQLDYEGELAIII 129

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304
           G     +   +A D+V GY+I  D+ A D +K     Q   GK++D FCP GP IVT D 
Sbjct: 130 GTSGRDLTPENALDHVFGYSIVNDVTARDLQKEHV--QFFRGKSLDGFCPFGPVIVTEDS 187

Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124
             +P ++ V+  +NG  +Q  +T   +  +  I+  +S  MTL  GDII TGTP GVG  
Sbjct: 188 F-DPTDVLVETRVNGQLRQSGSTKLMLRDVVTILTEVSRGMTLEAGDIIATGTPAGVGHG 246

Query: 123 RNPPEFLQPGDVITSEIENIGTFETRVEEF 34
             PP +LQ GDV+   IE IG  +  V+ +
Sbjct: 247 MKPPTYLQDGDVVDISIEGIGHLQNHVKAY 276


>UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=2; Proteobacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Fulvimarina pelagi HTCC2506
          Length = 337

 Score =  155 bits (376), Expect = 9e-37
 Identities = 73/200 (36%), Positives = 118/200 (59%)
 Frame = -3

Query: 660 LCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIG 481
           + +GLNY DH  E     P  P +F+K PS++ GP+D + +    +K +  E+EL VVIG
Sbjct: 128 IAIGLNYADHAAETGADLPVEPLVFSKAPSSICGPHDELPIPPGSTK-LDWEVELAVVIG 186

Query: 480 KKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI 301
           ++A  ++ + A ++V G+ +  D+    ++K +   Q + GK+      +GPW+VT D +
Sbjct: 187 ERAYNINETEAMNHVAGFCLCNDVSERAFQKERG-GQFIKGKSSPRTGALGPWLVTPDRL 245

Query: 300 GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYR 121
           G+PQ L++  S+NG  +Q+  T   +     I++ LS  M L PGD+I TGTP GVG   
Sbjct: 246 GDPQQLDLWLSVNGEIRQRGTTRDMLFSAAFIVSYLSKFMILEPGDVITTGTPSGVGAGM 305

Query: 120 NPPEFLQPGDVITSEIENIG 61
            PP+FL+ GD++T  I  +G
Sbjct: 306 TPPQFLREGDILTLGIGGLG 325


>UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia
           farcinica|Rep: Putative hydrolase - Nocardia farcinica
          Length = 285

 Score =  155 bits (375), Expect = 1e-36
 Identities = 80/209 (38%), Positives = 116/209 (55%), Gaps = 1/209 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTV 490
           K++C G NY+ H  E     PE P +F KF  T+   +  I L M  + A +  E EL V
Sbjct: 62  KIVCCGHNYRAHIAELGRAEPEFPTLFAKFADTLTAWDADITLGMAAADAGLDWEAELAV 121

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           V+G +  + D + A   + GYT+A D     W++  + +Q L GKA D   P+GP +VT 
Sbjct: 122 VVGAELRRADRATARAGIAGYTVANDFSVRTWQR--RTAQWLQGKAFDATTPLGPDLVTP 179

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DE      L + C +NGV +Q  +T+  +     +++ +S   TL PGD++LTGTPGGVG
Sbjct: 180 DEADPGDGLRITCRVNGVVEQCGSTDDLLFDPAALLSYISAFTTLRPGDVVLTGTPGGVG 239

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
           V  +PP  L  GDV+ +EIE IG    R+
Sbjct: 240 VAADPPRHLGDGDVVETEIEGIGLLRNRI 268


>UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Xanthobacter sp. (strain Py2)
          Length = 281

 Score =  154 bits (374), Expect = 2e-36
 Identities = 76/209 (36%), Positives = 114/209 (54%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           DK++CVGLNY DH  E   T    P +F ++  + VG    +   ++ S     E EL V
Sbjct: 71  DKIVCVGLNYHDHVNETGRTVTPNPMLFARYAGSQVGAGTALVKPLE-SDEFDYEGELAV 129

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           +IGK   ++  + A  +V GY    D    DW+++   SQ + GK        GPW+V++
Sbjct: 130 IIGKAGRRISEADALSHVAGYACYNDASVRDWQRHT--SQFMPGKTFAATGAFGPWMVSA 187

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI +P  L +   +NG Q Q ++ +  I  IP +IA  S ++ LLPGD+I++GTPGGVG
Sbjct: 188 DEIPDPTRLTLATRLNGAQVQHTSVDLMITPIPTLIAYTSTILPLLPGDVIVSGTPGGVG 247

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
             R P  F++ GDV+  E+  IG     +
Sbjct: 248 ARRTPKLFMKDGDVVEVEVSGIGVLRNPI 276


>UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=7; cellular organisms|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Methanococcus maripaludis
          Length = 202

 Score =  153 bits (372), Expect = 3e-36
 Identities = 86/209 (41%), Positives = 121/209 (57%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C GLNYKDH EE K+  P+ P IF K  S+++   + IK+    S+ V  E EL +V
Sbjct: 7   KIVCAGLNYKDHAEELKMKLPKEPVIFLKPTSSIIYNEEAIKIPK-ASERVDYEAELAIV 65

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    V      +Y+ G+TI  D+ A D ++  K  Q    K+ DTF PIGP IV+  
Sbjct: 66  IGKTCKSVKKEDVKNYIKGFTILNDVTARDLQE--KDGQWTRAKSFDTFSPIGPKIVSGI 123

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +  N   L ++  +NG  KQ SNTN  I  + +++  +S++MTL PGDII TGTP G+G 
Sbjct: 124 DANN---LKIQLRVNGKIKQDSNTNNMIFSVEELVEFVSSIMTLYPGDIISTGTPPGIGK 180

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
                  L+ GD++  EIENIG  +  VE
Sbjct: 181 -------LEKGDIVEIEIENIGILKNFVE 202


>UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG11179.1 - Gibberella zeae PH-1
          Length = 281

 Score =  153 bits (371), Expect = 4e-36
 Identities = 83/213 (38%), Positives = 118/213 (55%), Gaps = 6/213 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA--VVCEIELTV 490
           V+C+GLNY DH EE ++  P++P +F K  + + GP+D + L     +   +  E EL +
Sbjct: 66  VVCIGLNYTDHAEEAQMPIPKVPVVFFKPVTALAGPHDDLVLPHTSWEKGRLDYESELVI 125

Query: 489 VIGKKASKVDSSHAFDYVLGYTI--AQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPW 322
           VIGKKAS+V    A DYV  YT     DI    W+ + ++   Q    K  D   PIGP 
Sbjct: 126 VIGKKASRVSKDDALDYVFSYTFHAGNDISNRAWQLDPQLGGGQWCYSKCFDCSAPIGPA 185

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           IV+ D +G+   L ++ ++N  Q Q  NTN  I  + +I++ LS  MTLLPG  I TGTP
Sbjct: 186 IVSKDILGSAVGLGIRGTLNDTQSQDGNTNNMIFGVAEIVSFLSQGMTLLPGTFIFTGTP 245

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            GVG  + P   ++ GDV   EI+ IG    +V
Sbjct: 246 AGVGFGKKPQISVKEGDVTQVEIDGIGAIVNKV 278


>UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Methylobacterium sp. 4-46|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Methylobacterium sp. 4-46
          Length = 480

 Score =  152 bits (369), Expect = 7e-36
 Identities = 78/213 (36%), Positives = 118/213 (55%), Gaps = 4/213 (1%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K++ +G NY+ H  E     P+ P +FNK+ + +     TIKL   V++    E+EL +
Sbjct: 269 EKIIMMGFNYRHHAAETGTPIPKDPPLFNKYNNALNHHGGTIKLPTAVAREFDYEVELVI 328

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           V G++ S V  + A D V GY    D  A D +     SQ ++GK  D F P+GP++VTS
Sbjct: 329 VFGRECSNVSEAEALDCVAGYATGNDFSARDLQT--LTSQFMIGKTADGFAPLGPYLVTS 386

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           D + +P NL ++  +NGVQ+Q  NTN  I     +I+  S +MT+ PGDI  TGTP GV 
Sbjct: 387 DLVKDPNNLRLETRVNGVQRQDWNTNDMIFNCRQLISFASKMMTIKPGDIFYTGTPHGVI 446

Query: 129 VYRNPP----EFLQPGDVITSEIENIGTFETRV 43
                P    ++L+PGD +   +E +G    R+
Sbjct: 447 FGEKKPRAERQWLKPGDEVACSLEGLGELRFRL 479


>UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 282

 Score =  152 bits (368), Expect = 9e-36
 Identities = 84/203 (41%), Positives = 112/203 (55%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           DKVLCV  N+++   E K   PE P +F +F ++  G    +  K D S+A   E EL V
Sbjct: 71  DKVLCVATNFREPAREGK-PEPEYPLVFTRFANSFTGHGQPLA-KPDRSEAYDFEGELAV 128

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK   ++ +S A  +V GY    D    DW+K+   +Q   GK        GPWIVT+
Sbjct: 129 VIGKGGHRIPASEAMAHVGGYCCLNDGSVRDWQKHS--TQFTPGKNFHRSGSFGPWIVTA 186

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI +P  L ++  +NGV KQ+   ++ I  IP +IA  S    L+PGD+I TGTP G G
Sbjct: 187 DEIPDPTVLTLQTRVNGVVKQRIGIDRMIFDIPWLIAYFSTFTPLVPGDVIATGTPSGFG 246

Query: 129 VYRNPPEFLQPGDVITSEIENIG 61
             R PPE+L  GD I  EI  IG
Sbjct: 247 SSRTPPEYLSIGDAIEVEISEIG 269


>UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Bacillus halodurans|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus
           halodurans
          Length = 276

 Score =  151 bits (367), Expect = 1e-35
 Identities = 86/210 (40%), Positives = 125/210 (59%), Gaps = 2/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKL--TPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           K++   +NY  H +E  +  T   L F F K  ++++GPND I L  + ++ +  E+EL 
Sbjct: 75  KIVAAPVNYMSHKKEMNVDHTARVLGF-FLKATTSIIGPNDPIILPYN-NRRIDHELELA 132

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
            VIGK+A  V   +A DY+ GYT   D+      KN++  +  L K+ DTF PIGPWIVT
Sbjct: 133 FVIGKRAKHVKKENAHDYIFGYTGLNDVTVRP-TKNRE-EERCLRKSFDTFTPIGPWIVT 190

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           SDEI +PQNL +   +N   +Q  NTNQ +  I +++   S+VMTL PGD+I TGTP GV
Sbjct: 191 SDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTLEPGDLIATGTPDGV 250

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G        ++ GD +T ++E+IG+F   V
Sbjct: 251 GP-------IKDGDTVTLQMESIGSFSNPV 273


>UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Desulfitobacterium hafniense|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 251

 Score =  151 bits (366), Expect = 2e-35
 Identities = 85/208 (40%), Positives = 118/208 (56%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+GLNY  H EE      + P IF K  +++VGP D I L   +S+ V  E EL VV
Sbjct: 56  KIVCIGLNYAKHIEELGHDFHDDPVIFLKPVTSLVGPEDEIILPA-MSQQVDYEAELVVV 114

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK A  +    A DY+ G+T   D+ A D +K  K  Q    K  DTFCPIGPWIV   
Sbjct: 115 IGKTAKDLAEDQAEDYIFGFTCGNDVTARDLQK--KDGQWTRSKGFDTFCPIGPWIVRDL 172

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +    +N+ ++  +NG  KQ S T+  IH +P +++ +S +MTL PGD+I+TGTP GVG 
Sbjct: 173 DY---RNVKIRSVLNGEVKQSSQTSHLIHSVPKLVSYISKIMTLNPGDLIMTGTPEGVGP 229

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                  ++ GD I  +I+ IG     V
Sbjct: 230 -------MKTGDAIAIDIKGIGRLHNLV 250


>UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=4; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Delftia acidovorans SPH-1
          Length = 309

 Score =  151 bits (365), Expect = 2e-35
 Identities = 75/208 (36%), Positives = 113/208 (54%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNYK H  E +    E P +F +F  ++    D + L+   S+    E EL  V
Sbjct: 98  KLICVGLNYKTHVAETRRADSEHPSLFLRFNDSLAADGDEL-LRPAFSERFDWEGELAFV 156

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+    +    AFD++ GY    D+   DW+++    Q   GK      P GPW+VT D
Sbjct: 157 IGRGGRHIAKEDAFDHIAGYACFNDVSVRDWQRHTH--QFTPGKNFPGTAPFGPWLVTRD 214

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ + ++L ++  +NG   Q+++    I  IP I+A +S    L PGD+I TGTPGGVG 
Sbjct: 215 EVADVRSLALQTRLNGSVMQQASLGDLIFDIPTIVAYVSRFTPLSPGDVIATGTPGGVGD 274

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
            R PP +++ GDV+  EI  +G    R+
Sbjct: 275 RREPPLYMKHGDVVEVEITGLGVLRNRI 302


>UniRef50_Q88Y59 Cluster:
           2-hydroxyhepta-2,4-diene-1,7-dioateisomerase /
           5-carboxymethyl-2-oxo-
           hex-3-ene-1,7-dioatedecarboxylase; n=1; Lactobacillus
           plantarum|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioateisomerase /
           5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase
           - Lactobacillus plantarum
          Length = 276

 Score =  150 bits (364), Expect = 3e-35
 Identities = 73/209 (34%), Positives = 116/209 (55%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           ++  VG+NY+DH  E  +T P++P IF KF S++   N T+            E EL V+
Sbjct: 71  QIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATH---GPETDWETELVVM 127

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    + ++ A  +V G  + +D+     +      Q  +GK+ + + P+GPW+ T D
Sbjct: 128 IGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAPVGPWLTTVD 187

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ N  +  +  ++NG   Q++  +Q I K+PD++  LS V  L PGD+I TGTP G GV
Sbjct: 188 ELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIFTGTPSGTGV 247

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
            RNP  FLQ GD +  +I ++GT    ++
Sbjct: 248 GRNPQVFLQAGDQLCGQITHLGTLNITIK 276


>UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep:
           Putative oxygenase - Bordetella bronchiseptica
           (Alcaligenes bronchisepticus)
          Length = 287

 Score =  150 bits (363), Expect = 4e-35
 Identities = 75/211 (35%), Positives = 112/211 (53%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           DK+LC+GLNY+ H EE  +  P  P  F +F  ++      + L+   S     E EL V
Sbjct: 77  DKILCIGLNYRLHAEEAGMAIPARPSTFVRFAGSLAAQGQPV-LRPAESDQFDYEAELAV 135

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           +IGK A +V  + A ++V GY    +    DW+++   +Q   GK        GPW+VT+
Sbjct: 136 IIGKPARRVSQARAMEHVAGYACLAENSVRDWQRHS--TQATPGKNFVRSGAFGPWLVTA 193

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DE G P+ + V   +NG   Q  +    I  +  +++ LS    LLPGD+I TGTP GVG
Sbjct: 194 DEAGAPEAMTVIGRLNGETVQHDSVANMIFTVAQLVSYLSTFAELLPGDVIATGTPAGVG 253

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           + R PP +L+PGDV   +I  +G     V++
Sbjct: 254 MSRKPPRYLRPGDVFEVDISGVGVLRNPVDD 284


>UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=6; Enterobacteriaceae|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Enterobacter sp. 638
          Length = 287

 Score =  150 bits (363), Expect = 4e-35
 Identities = 82/211 (38%), Positives = 114/211 (54%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K+LCVG+NY +  +E     P  P +F +FP +  G N  + LK   S     E EL V
Sbjct: 73  EKILCVGMNYAEKRQEFDQHNPA-PTLFVRFPDSQTGHNSPV-LKPRHSSEFDYEGELAV 130

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           +IGK    +    A  +V GY+   D  A DW+     +    GK        GPW+ T+
Sbjct: 131 IIGKGGENISRDDALRHVAGYSCYMDGSARDWQH----TWFTAGKNWRQTGAFGPWMATA 186

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI +P  L ++  +NG   Q+ NT+  IHK+ ++I  +S    L PGD+I+TG+PGGVG
Sbjct: 187 DEIPDPHRLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLSPGDVIITGSPGGVG 246

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
             RNPP F+Q GD I  EIENIG     + E
Sbjct: 247 KKRNPPLFMQEGDRIEVEIENIGHLSNVIME 277


>UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1,
           7-dioate isomerase; n=1; Thermoplasma acidophilum|Rep:
           Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase
           - Thermoplasma acidophilum
          Length = 315

 Score =  149 bits (362), Expect = 5e-35
 Identities = 85/210 (40%), Positives = 120/210 (57%), Gaps = 2/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+LC+G+NY +H +E +    E P IF KF  +++G  D I +  D +K +  E EL V+
Sbjct: 113 KILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGNMDDITVPKD-AKQIDYEGELVVI 171

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+ +   +SS     + GYTI  D+ A D +   + SQ LLGKA+ TF PIGP IV  +
Sbjct: 172 IGRSSGTAESS-----IFGYTIGNDVSARDLQF--RTSQWLLGKALPTFAPIGPVIVGKN 224

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV-- 133
           E+G  ++L +   +NG  +Q  NT+  I  +  I+  LS    L PGDII TGTP GV  
Sbjct: 225 ELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDYLSGYFNLGPGDIIFTGTPEGVIL 284

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G+  N   +L+ GDVI   I  IGT   R+
Sbjct: 285 GLPENERVWLKHGDVIDVSITGIGTLTNRI 314


>UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase;
           n=1; Cenarchaeum symbiosum|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase -
           Cenarchaeum symbiosum
          Length = 288

 Score =  149 bits (362), Expect = 5e-35
 Identities = 79/208 (37%), Positives = 116/208 (55%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+ C+  NY DH ++Q  +PP+ P I  K  + + G  D I +   V K +  E+EL ++
Sbjct: 79  KIFCLAFNYADHAQDQDRSPPDEPVIVMKPRTALCGNGDDIVMPPFV-KELDYEVELALI 137

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK+   VD   A + + GYTI  D+ A D +      Q    K +DTF P GPWI ++D
Sbjct: 138 IGKRCRDVDVIGAKEAIFGYTILNDVSARDIQFRD--GQFTRAKGLDTFAPCGPWITSAD 195

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +P  L +   +NG  +Q S+T++   K  +I+++LS+ MTL  GDII TGTP GV +
Sbjct: 196 EVQDPGRLKMTTKVNGRARQDSSTSKMHIKPFEIVSKLSSSMTLEKGDIISTGTPSGVAL 255

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                E+L  GD I  EIE +G     V
Sbjct: 256 NNPDSEYLAAGDEIEMEIEGLGVLRNTV 283


>UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3;
           cellular organisms|Rep: Uncharacterized protein AF_2225
           - Archaeoglobus fulgidus
          Length = 250

 Score =  148 bits (358), Expect = 1e-34
 Identities = 85/202 (42%), Positives = 118/202 (58%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ VGLNY DH EE  +  PE P +F K  + V+G +D I L   +S+ V  E EL VV
Sbjct: 45  KIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCIILPQ-ISQRVDYEGELAVV 103

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           I +    V  ++A DY+LGYT   D+ A D +   K  Q    K+ DTF P+GP+I    
Sbjct: 104 IAEDCRNVPETNAADYILGYTCFNDVTARDLQA--KDGQWTRAKSFDTFAPLGPYIA--- 158

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +P  L ++  +NG   QKSNT+  I  +  +++ +S+VMTL  GD+I TGTP GVG+
Sbjct: 159 EIDDPSKLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTLKAGDVIATGTPAGVGM 218

Query: 126 YRNPPEFLQPGDVITSEIENIG 61
                  L+ GDV+  EIE IG
Sbjct: 219 -------LKDGDVVEVEIEKIG 233


>UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358;
           n=1; Citrobacter koseri ATCC BAA-895|Rep: hypothetical
           protein CKO_03358 - Citrobacter koseri ATCC BAA-895
          Length = 295

 Score =  147 bits (357), Expect = 2e-34
 Identities = 82/211 (38%), Positives = 114/211 (54%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K+LCVG+NY +  +E     P  P +F +F  +  G N  + LK   S     E EL V
Sbjct: 81  EKILCVGMNYAEKRQEFDQHDPA-PTLFVRFADSQTGHNMPV-LKPRHSHEFDYEGELAV 138

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           +IG     +   HA D+V GY+   D  A DW+     S    GK        GPW+VT+
Sbjct: 139 IIGNGGENISRDHALDHVAGYSCYMDGSARDWQH----SWFTAGKNWRQTGAFGPWMVTA 194

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI +P  L ++  +NG   Q+ NT+  IHK+ ++I  +S    L  GD+I+TG+PGGVG
Sbjct: 195 DEIPDPHQLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLNSGDVIITGSPGGVG 254

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
             RNPP F+Q GD I  EIE+IG     + E
Sbjct: 255 KKRNPPLFMQEGDRIEVEIEHIGHLSNVIME 285


>UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep:
           Lmo2266 protein - Listeria monocytogenes
          Length = 282

 Score =  147 bits (356), Expect = 3e-34
 Identities = 79/213 (37%), Positives = 121/213 (56%), Gaps = 2/213 (0%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496
           + ++ +G NY +H  E   K   PE   +F K  ++++  N  I+L  +++  +  E EL
Sbjct: 72  NNIIAIGKNYYNHVLEMGSKEDVPEHILVFTKSANSLLPHNGNIELHQNITGQLDYEGEL 131

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
            V+IG+K   +    A   + G+TI  DI A D +K  K  Q  LGK++D  CPIGP+++
Sbjct: 132 AVIIGEKVRDISEQEALSAIFGFTILNDITARDLQKKHK--QFYLGKSLDASCPIGPFVL 189

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
            ++    P   +++  +NG  +Q  +T++FI  +  II+ LS   TLLPGDII TGTP G
Sbjct: 190 ENNANKEPV-FHIETKVNGEVRQSDSTDKFIFGLARIISDLSKGHTLLPGDIIATGTPSG 248

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           VG    PP FLQ GD+I   I+ IGT   +V +
Sbjct: 249 VGNGMTPPTFLQDGDIIEITIDKIGTLTNKVRK 281


>UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Oceanicola batsensis HTCC2597|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Oceanicola batsensis HTCC2597
          Length = 252

 Score =  147 bits (355), Expect = 3e-34
 Identities = 85/208 (40%), Positives = 115/208 (55%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNYK H EE     PE P +F   PS V+    TI L    ++ +  E E+ +V
Sbjct: 55  KLVCVGLNYKRHAEESGAAIPEEPMLFMCAPSAVIPDGGTILLDSQDAR-IDYEAEIAIV 113

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK+A  +  + A   + GYTI  D+   D++K  K  Q    K+ DT+ P+GPWI T  
Sbjct: 114 IGKQARNLPEADARSCIFGYTICNDVSNRDYQK--KDGQFTRAKSFDTYKPLGPWIETGL 171

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +   P N  +    NG  +Q+SNT+  I  I  I+A +S +MTL PGD+I+TGTP GVG 
Sbjct: 172 D---PDNAAISLRQNGELRQQSNTSDMIFSIDRIVAFVSGIMTLNPGDVIITGTPEGVGP 228

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
            R+       GD I  EIE IGT    V
Sbjct: 229 MRS-------GDRIEIEIEGIGTLANSV 249


>UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Clostridium beijerinckii NCIMB
           8052|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Clostridium beijerinckii NCIMB 8052
          Length = 294

 Score =  146 bits (354), Expect = 4e-34
 Identities = 84/218 (38%), Positives = 116/218 (53%), Gaps = 7/218 (3%)
 Frame = -3

Query: 672 NDKVLCVGLNYKDHCEEQKLTPPEL-----PFI--FNKFPSTVVGPNDTIKLKMDVSKAV 514
           N  ++C+G+NY +H  E      E      P+   F+K  +T     D I     +  ++
Sbjct: 79  NQDIICLGINYMEHAVESARYKNEAFGGDRPYAVYFSKRVNTATADGDYIPSYPQIVDSL 138

Query: 513 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 334
             E EL V+IGK A  V    AFDYV GYTI  D+ A + +   K  Q   GK++D F P
Sbjct: 139 DYEAELAVIIGKDAKDVPKEKAFDYVFGYTIINDVSARNLQTRHK--QWYFGKSLDGFTP 196

Query: 333 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 154
           +GP IVT +E  NP  L +   +NG  +Q S T+  I  I D+I  LS  +TL  G II 
Sbjct: 197 MGPCIVTKNEFVNPPVLRICSRVNGELRQNSTTDLMITSIQDVIHELSQGITLKVGTIIA 256

Query: 153 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
            GTP GVG+   PP+FL+ GD++  EIE IG  +  V+
Sbjct: 257 MGTPAGVGMGFIPPKFLKTGDIVECEIEGIGCLKNIVK 294


>UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase / 5-carboxymeth..; n=42; Bacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase /
           5-carboxymeth.. - Yersinia pseudotuberculosis
          Length = 254

 Score =  146 bits (353), Expect = 6e-34
 Identities = 81/207 (39%), Positives = 114/207 (55%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           +  +GLNY DH  E   +PP+ P IF K P +  G    + ++ D  + +  E EL VV+
Sbjct: 46  LFALGLNYVDHAAELDFSPPKEPLIFIKAPHSFTGHRQ-VSVRPDNIEYMHYEAELVVVV 104

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304
           GK A  ++ +HA DYV GYT+  D    D+ +N     L + K+ DT  PIGPWIV   +
Sbjct: 105 GKPARYLNPAHAMDYVAGYTLCNDYAVRDYLENYYRPNLRV-KSRDTLTPIGPWIVDKAD 163

Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124
           I NP NL ++  +NG   Q+ NT   I  IP ++A LS  +TL PGD+I TGTP G+   
Sbjct: 164 IPNPHNLVIRTWVNGELCQRGNTADLIFDIPFLMAYLSEFITLQPGDMIATGTPKGL--- 220

Query: 123 RNPPEFLQPGDVITSEIENIGTFETRV 43
                 + PGD +  E++ IG    RV
Sbjct: 221 ----SNVVPGDEVVVEVDGIGCLLNRV 243


>UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase;
           n=1; Methanopyrus kandleri|Rep: 2-keto-4-pentenoate
           hydratase hydratase - Methanopyrus kandleri
          Length = 264

 Score =  146 bits (353), Expect = 6e-34
 Identities = 84/205 (40%), Positives = 120/205 (58%), Gaps = 3/205 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496
           K++C GLNY++H EE +   +  P  P +  K P+ V+G  DT+KL  + ++ V  E+EL
Sbjct: 65  KIICFGLNYREHVEELREMGMDVPSEPVMTMKAPTAVIGHLDTVKLPRE-ARRVDHELEL 123

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
            VVIG++  KV    A D VLG+TI  D+ A D EK +   Q +  K+ DTF P+GPWI 
Sbjct: 124 AVVIGERCRKVSPEEARDAVLGFTIINDVTARDIEKRE--GQWVRAKSYDTFAPLGPWIE 181

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           T  E   P  L ++  +NG  +Q++ T+  +    ++++  S VMTL PGDII TGTP G
Sbjct: 182 TELE---PDGLEMELRVNGEVRQRATTDDMVRDPYELVSFTSRVMTLEPGDIIATGTPPG 238

Query: 135 VGVYRNPPEFLQPGDVITSEIENIG 61
           VG        ++P D I  EIE IG
Sbjct: 239 VGP-------MEPDDKIELEIERIG 256


>UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Burkholderiaceae|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 306

 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/212 (39%), Positives = 118/212 (55%), Gaps = 7/212 (3%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQ--KLTPPE--LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499
           ++     NY +H  E   +L P E   P++F K  ++VV P     +    ++ V  E+E
Sbjct: 92  RIFAAASNYYEHAREMGTELAPREESTPYMFMKAETSVV-PTLAEVVMPPHAERVDWEVE 150

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---QLLLGKAMDTFCPIG 328
           L VVIGK    +  + AFDYV GYTI  D+ A D  +            GK+ DTF P+G
Sbjct: 151 LAVVIGKPGRHIAVADAFDYVAGYTILNDVSARDLNRRTDYPFKHDWFRGKSFDTFGPLG 210

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           PW+V    I  PQNL ++ ++NG   Q  NT + I  I + I  LS+++TL PGD+I TG
Sbjct: 211 PWLVPRACIAEPQNLRMRLAVNGEMMQDGNTGEMIFSIAEQIHYLSSILTLQPGDLIATG 270

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 52
           TP GVG+ R    +LQPGDV+ + I+ IG+ E
Sbjct: 271 TPTGVGMGRG--IYLQPGDVMVASIDGIGSIE 300


>UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 356

 Score =  145 bits (351), Expect = 1e-33
 Identities = 76/209 (36%), Positives = 114/209 (54%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           DK++ VG NY+ H  E     P+ P +F +FPS+ VG    + +   +S     E EL V
Sbjct: 139 DKIIAVGFNYRGHLIETGTPLPDYPSLFVRFPSSQVGHGQPV-VAPSLSGEFDFEGELAV 197

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           +IG+ A +V  + A D+V+GY+   +    D++ + +  Q+  GK       IGPW+ T+
Sbjct: 198 IIGRPAWRVAEADAMDHVVGYSCFAENSVRDYQAHAR--QVTAGKNFLASGAIGPWLTTA 255

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DE+G+P  L +   +NG   Q+      I  IP +IA ++    LLPGDII TGTP GVG
Sbjct: 256 DEVGDPSTLELTTRLNGAVVQQDRLTSLIFTIPQLIAYITRFTRLLPGDIISTGTPDGVG 315

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
             R+P  +L PGDV+  +I  +G     V
Sbjct: 316 FLRDPKIWLAPGDVLEIDIPRVGLLRNAV 344


>UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4;
           Pezizomycotina|Rep: RIB40 genomic DNA, SC138 -
           Aspergillus oryzae
          Length = 582

 Score =  145 bits (351), Expect = 1e-33
 Identities = 82/222 (36%), Positives = 123/222 (55%), Gaps = 9/222 (4%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 529
           + G D VL VG NY +H +E          K   P  P IF K  ++++GP + I L   
Sbjct: 75  ISGRD-VLAVGKNYVEHAKEFNASGYDASDKSDQPTHPVIFTKRATSIIGPEEPILLHPK 133

Query: 528 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 349
            +  V  E E+ V+IGK   ++   +A D+V GYTI  D+ A + +++ K  Q  LGK+ 
Sbjct: 134 FTSTVDYEGEIGVIIGKPGFQISEENASDHVWGYTIVNDMTARERQRDHK--QFFLGKSP 191

Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169
           DTFCP+GP  V  + +  P+NL ++  +N   +Q+++ +  I  IP +IA +S   TL  
Sbjct: 192 DTFCPMGPVAVPKESL--PENLKIQTFVNQELRQEASLSDLIFSIPTLIATISAGQTLQT 249

Query: 168 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           GD+I TGTP GVG    P +FLQ GD I+  +  +GT   R+
Sbjct: 250 GDVIATGTPAGVGFGFRPMKFLQTGDEISVSVTGLGTLTNRM 291


>UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Lawsonia intracellularis (strain
           PHE/MN1-00)
          Length = 257

 Score =  144 bits (349), Expect = 2e-33
 Identities = 81/211 (38%), Positives = 120/211 (56%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+ +NY +  +E +   P  P  F K PS++VG    I L  ++ + VV E EL +V
Sbjct: 51  KIICIDINYHEKAQELQQPIPTNPTFFFKPPSSIVGNGQPILLPTNIGR-VVSEAELCIV 109

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+   KV    A +Y+ GYT A DI A D ++ +  +     KA +TFCP+GPWI T  
Sbjct: 110 IGQTCYKVTPEAASNYIFGYTCANDITAKDIQQQEYTTSH--AKAYNTFCPVGPWIET-- 165

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           ++ N +NL ++ SIN    Q S T   I    ++I+ LSN+MTL PGD+ILTGTP G   
Sbjct: 166 DVPNIENLQIRNSINSELGQVSTTADMIFPPLELISFLSNIMTLNPGDLILTGTPKG--- 222

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34
                  +  GD++ + IEN+G     +EE+
Sbjct: 223 ----SLLISDGDIVQTSIENVGILINPIEEY 249


>UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Herpetosiphon aurantiacus ATCC
           23779|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Herpetosiphon aurantiacus ATCC 23779
          Length = 293

 Score =  144 bits (349), Expect = 2e-33
 Identities = 76/175 (43%), Positives = 100/175 (57%), Gaps = 6/175 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQ------KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           V CVGLNY  H  E       ++  PE P  F K P+ +  P   I +   VS+ +  E+
Sbjct: 76  VFCVGLNYAAHARESLQAKGLEVKMPEHPVFFTKPPTAINSPTGEIVIDPAVSERIDWEV 135

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL VVIGK    +    A ++V GYT+  D+ A D +   +  Q   GKA+D  CP+GPW
Sbjct: 136 ELGVVIGKAGKNISHEQAMEHVWGYTVINDVSARDLQMRHQ--QFFKGKALDGSCPMGPW 193

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
           I+TSDE+ +P NL V+  +NG  KQ+SNTN  I  IP +I  LS  MTL PGDII
Sbjct: 194 IITSDELTDPHNLVVRLRVNGEIKQESNTNDLIFNIPTLIHVLSQGMTLEPGDII 248


>UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase; n=4; Deinococci|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase - Deinococcus radiodurans
          Length = 262

 Score =  144 bits (348), Expect = 2e-33
 Identities = 81/208 (38%), Positives = 119/208 (57%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+ + LNY DH  E     PE P +F K P+T + P+    +    +K +  E+EL +V
Sbjct: 46  KVIALALNYADHVAELGFKAPEEPVMFLK-PNTSLLPHQGTVIYPRGAKFMHYEVELGIV 104

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+ A +V +  A DYV GYTIA D+   D+  N      +  K  DTF P+GP++V++D
Sbjct: 105 IGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNY-YRPPMRAKGWDTFGPLGPYLVSAD 163

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +P NL ++  +NG  +Q+ +T   I K P++I  +S  MTL  GD+ILTGTP GV  
Sbjct: 164 EVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKGV-- 221

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                  + PGDV+  EI+ +G  E  V
Sbjct: 222 -----SHVHPGDVMRLEIDGLGALENPV 244


>UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein;
           n=1; Rhizobium leguminosarum bv. viciae 3841|Rep:
           Putative FAA hydrolase family protein - Rhizobium
           leguminosarum bv. viciae (strain 3841)
          Length = 282

 Score =  144 bits (348), Expect = 2e-33
 Identities = 82/189 (43%), Positives = 107/189 (56%), Gaps = 11/189 (5%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP-----------PELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517
           V CVG NY  H  E   +            PE P IF K  S++  P   I L   + +A
Sbjct: 87  VFCVGKNYHAHAHEFTKSGFDAGATAAEAIPEHPIIFTKPSSSLARPFGDIPLWPGLDEA 146

Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337
           V  E EL VVIGK    + +  A D+V GYT+  D+ A D +K  K  Q  LGK +D F 
Sbjct: 147 VDYEAELAVVIGKAGRFITAERALDHVFGYTVFNDVTARDLQKKHK--QWFLGKGIDGFG 204

Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
           PIGPWIVT DE+ +  N+ + C++NG ++QK++T   I  IP +I  +S  +TLLPGDII
Sbjct: 205 PIGPWIVTKDEL-DIANVEITCTVNGEERQKTSTKDLIFDIPTLIEVISRSVTLLPGDII 263

Query: 156 LTGTPGGVG 130
            TGTP GVG
Sbjct: 264 ATGTPAGVG 272


>UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Hyphomonas neptunium ATCC 15444|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 277

 Score =  143 bits (347), Expect = 3e-33
 Identities = 78/212 (36%), Positives = 112/212 (52%), Gaps = 4/212 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQ----KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499
           K+L +G+NY  H  E         PE+   FNK  + V GP D + L   VS  +  E E
Sbjct: 59  KILGIGVNYAAHAAESVSFINTAKPEVQKWFNKQATAVNGPYDPVHLPR-VSSQLDYEGE 117

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319
           L  VIGK    V +  A + V G+ I  D    DW+K  +   +++GK  DT  P GP +
Sbjct: 118 LVAVIGKHGRHVPAERAMEIVAGFCIGCDYSVRDWQKASQT--MIMGKGFDTHAPFGPAL 175

Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
           VT DE+G+  +L ++  +NG  +Q       IH +   IA L+   TL PGD+I TGTP 
Sbjct: 176 VTPDELGDISDLEIRSFVNGELRQSGRPRDMIHDVGAQIAHLTAAFTLEPGDVIFTGTPA 235

Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           GVG   +PP++L+ GD +  EI+ +G  E  +
Sbjct: 236 GVGAGFDPPKWLKAGDRVRIEIDRLGHIENAI 267


>UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584;
           n=2; Vibrio|Rep: Putative uncharacterized protein VV1584
           - Vibrio vulnificus (strain YJ016)
          Length = 259

 Score =  143 bits (346), Expect = 4e-33
 Identities = 78/207 (37%), Positives = 112/207 (54%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           +  +GLNY DH  E    PP+ P +F K  +T+           D+ + +  E EL  V+
Sbjct: 48  IFALGLNYADHASELAFEPPKEPLVFLKGANTLTAHQQPSYRPNDI-EFMHYECELVAVV 106

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304
           GK+A  V    A DY+ G+TI  D    D+ +N     L + K+ D+ CPIGPWIV  D+
Sbjct: 107 GKEARNVKREDAMDYIQGFTICNDYAIRDYLENYYRPNLRV-KSRDSLCPIGPWIVDCDD 165

Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124
           I +  NL +   +NG   Q+ NT+  I  +P +I  LS+ MTL PGD+I TGTP G+   
Sbjct: 166 IEDVNNLALTTHVNGELTQQGNTSDMIFDVPFLIEYLSSFMTLKPGDLIATGTPKGL--- 222

Query: 123 RNPPEFLQPGDVITSEIENIGTFETRV 43
               + +QPGDV+   IE +G+ E  V
Sbjct: 223 ----KDIQPGDVVRCTIEGVGSLENPV 245


>UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Hyphomonas neptunium ATCC 15444|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 281

 Score =  143 bits (346), Expect = 4e-33
 Identities = 78/208 (37%), Positives = 114/208 (54%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+GLNYK+H +E     P  P +F K   ++V P+    L+  VS+    E E+ VV
Sbjct: 75  KLVCLGLNYKNHVDETHNDLPPNPALFTKVADSLV-PHGEAVLRPKVSEQFDYEGEICVV 133

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    +    A D+V GYTI  D    D++K+     +  GK       +GPWIVT+D
Sbjct: 134 IGKGGRHISRETALDHVFGYTIMLDGSVRDYQKHS----VSAGKNFWRSGALGPWIVTAD 189

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           EI +P  + ++  +NG   Q +  +  ++ IP  IA +S    L PGD+I TGTPGGVG 
Sbjct: 190 EIPDPSVMKLETRLNGETVQSTTADLMLYDIPTAIAYVSQWTPLAPGDVIATGTPGGVGA 249

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
            R PP +++ GDVI  ++  IG     V
Sbjct: 250 RRKPPLWMKAGDVIEVDVSQIGVLSNPV 277


>UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA)
           hydrolase; n=1; Burkholderia xenovorans LB400|Rep:
           Putative fumarylacetoacetate (FAA) hydrolase -
           Burkholderia xenovorans (strain LB400)
          Length = 257

 Score =  142 bits (345), Expect = 5e-33
 Identities = 79/204 (38%), Positives = 113/204 (55%), Gaps = 1/204 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           ++  VG+NY  H  E     P +P  F    +  +GP + I ++   ++ V  E EL +V
Sbjct: 55  RLFAVGMNYVGHIAEAGAKTPVIPQFFMMPTTAAIGPGEAI-VRPREAQVVHHEAELAIV 113

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK-ISQLLLGKAMDTFCPIGPWIVTS 310
           IG++  ++D   A D+V GYT A D+     +  +     LL+GKA DTFCP+GP I T 
Sbjct: 114 IGRRGRRIDVERALDHVFGYTCANDVSERVIQNREMGYGCLLVGKAFDTFCPLGPVIATG 173

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
            + GN   L V+ S+NG  +Q  NT+  +  +P I++ LS  +TLLPGD+ILTGTP GVG
Sbjct: 174 LDAGN---LRVRASVNGSPRQDGNTSDLLFTVPHIVSYLSQAVTLLPGDVILTGTPSGVG 230

Query: 129 VYRNPPEFLQPGDVITSEIENIGT 58
                   L  GDV    I+ IGT
Sbjct: 231 P-------LLSGDVCEITIDGIGT 247


>UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;
           Ascomycota|Rep: Degradation of aromatic compounds -
           Pichia stipitis (Yeast)
          Length = 293

 Score =  142 bits (345), Expect = 5e-33
 Identities = 74/212 (34%), Positives = 113/212 (53%), Gaps = 5/212 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           V CVGLN+  H +E   TPP  P IF K   +V    + I +          E EL +VI
Sbjct: 79  VKCVGLNFMKHIQEGGRTPPPFPSIFYKTSFSVADFGEDIPIPKIAQSKCDYEGELCIVI 138

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGKAMDTFCPIGPWIV 316
           GK    +    A  YV GY    D+ + +W+K+ +    + Q    K+ D + P+GP +V
Sbjct: 139 GKTGKNIKEEEALSYVAGYVTGNDVSSRNWQKDPEFAGSVPQWCFSKSFDKYAPLGPALV 198

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           +   I NP NL+++ ++NG  +Q +NT+  +  +P II+ +S   TL  G +I+TGTP G
Sbjct: 199 SPQVIQNPGNLSLQTTVNGEIRQDANTDDLLFGVPRIISFISQSTTLEMGTVIMTGTPSG 258

Query: 135 VGVYRNP-PEFLQPGDVITSEIENIGTFETRV 43
           V +   P P +LQ GDV+   I+ IGT   ++
Sbjct: 259 VALGMKPTPVYLQNGDVVEVAIDQIGTLSNKM 290


>UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=9; Proteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Burkholderia cenocepacia PC184
          Length = 306

 Score =  142 bits (343), Expect = 9e-33
 Identities = 76/210 (36%), Positives = 115/210 (54%), Gaps = 1/210 (0%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K+LCVGLNY DH  E        P +F +F S+++G +  I L    S+ +  E EL  
Sbjct: 90  NKILCVGLNYLDHSMETGFAKQTYPTVFARFASSLIGHDQPIALPAQSSQ-LDYEGELVA 148

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIGK    +    A D+V GY++  D+   D++   +  Q  +GK  D     GPW VT+
Sbjct: 149 VIGKAGRGITRERALDHVAGYSLFNDVTLRDYQF--RTPQWTMGKNFDGTGGFGPWFVTA 206

Query: 309 DEIGNP-QNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           DE+    + L ++  +NG   Q+++T+  I  I  ++  LS VMTL  GD+I+TGTP G+
Sbjct: 207 DELPRGCKGLRIQTRLNGAVVQEASTSDMIFDIETLVVMLSEVMTLQAGDLIVTGTPAGI 266

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G+ R P  +++ GDV   EIE +G     V
Sbjct: 267 GMAREPQLWMKAGDVCEVEIEQLGVLRNAV 296


>UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=6; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Burkholderia cepacia (strain ATCC 53795 / AMMD)
          Length = 291

 Score =  141 bits (342), Expect = 1e-32
 Identities = 73/211 (34%), Positives = 117/211 (55%), Gaps = 1/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+G N+ DH +E     P  P IF +  ++++   D + ++  VS+ +  E EL VV
Sbjct: 79  KIVCLGHNFYDHAKEGGNLKPVYPLIFFRGATSLIAHGDPV-IRPFVSEKLDYEAELVVV 137

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    V   +A D+V GY    D+   D++K  + +Q  +GK  D     GPW+VTSD
Sbjct: 138 IGKTGRHVKRENALDHVFGYACFNDVSVRDYQK--RTAQWTIGKNFDGTGAFGPWLVTSD 195

Query: 306 EIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           E+      L ++  +NG   Q++NT   I  + + I  L+  +TL PGD+++ GTP GVG
Sbjct: 196 ELPPGAAGLKLELRLNGEAMQRANTADMIWSVAETIELLTECLTLEPGDVVVMGTPAGVG 255

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
             R PP +++ GD +  +IE IG     V++
Sbjct: 256 FARTPPVWMKAGDRVEVDIEGIGVLSNVVQD 286


>UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Polynucleobacter sp.
           QLW-P1DMWA-1|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 309

 Score =  141 bits (342), Expect = 1e-32
 Identities = 85/220 (38%), Positives = 118/220 (53%), Gaps = 9/220 (4%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTP-----PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505
           DK LCVG NY+ H EE K T      P+ P  F K  S + G N T+     ++K +  E
Sbjct: 91  DKFLCVGKNYRTHLEELKRTNLIKEIPQEPTSFIKLNSCLSGHNATVVRPKGITK-LDYE 149

Query: 504 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPI 331
            EL  V+GK+A     S A DY+ G TI  D+   D +  +  S  +   GK +  F P+
Sbjct: 150 PELVFVMGKRALGAKKSEAMDYIGGVTILNDLTCRDLQLREVASGSRFWTGKNIPGFGPL 209

Query: 330 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151
           GP I+T DEI NP +L + CS+NG ++ + NT   I KI DI+   S  + +  GD+  T
Sbjct: 210 GPEIITIDEIPNPYDLWMTCSVNGEERMRVNTQDQIWKISDILEHFSRFIPIEAGDMFST 269

Query: 150 GTPGGVGVYRNPPE--FLQPGDVITSEIENIGTFETRVEE 37
           G PGGV V +   E  +L+PGDV+   I+ I T  T + E
Sbjct: 270 GAPGGVAVGKENAEALYLKPGDVVECAIDGISTLRTTIAE 309


>UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Syntrophobacter fumaroxidans
           MPOB|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 235

 Score =  141 bits (342), Expect = 1e-32
 Identities = 83/224 (37%), Positives = 117/224 (52%), Gaps = 14/224 (6%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTP--------PELPFIFNKFPSTVVGPNDTIKLKMDVSK--- 520
           K++ +GLNY+ H  E             PE P +F K P+ ++GP ++I +   + +   
Sbjct: 19  KIIALGLNYRAHIAESTTVKVRGFTDEVPEEPILFPKTPNVLIGPGESIVIPAFLKEYGF 78

Query: 519 ---AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 349
                  E EL V+I  +   V    A  +V GYT   D+   + +   +      GK++
Sbjct: 79  PEPRTDYEAELAVIIKDECKNVGPGDALKHVFGYTCMNDVSQRNLQTGDRAGWFR-GKSL 137

Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169
           DTF PIGP IV  D++G+P NL + C +NGV  Q SNT   I KIP+IIA +S    L+P
Sbjct: 138 DTFGPIGPVIVRPDDLGDPHNLRICCRLNGVTVQDSNTGSMIFKIPEIIAFVSRNFKLMP 197

Query: 168 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           GD+I+TGTP GVG  R+       GDV+  EIE IG     V E
Sbjct: 198 GDVIVTGTPSGVGPIRH-------GDVVEVEIEKIGILRNPVVE 234


>UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate
           isomerase; n=4; Halobacteriaceae|Rep:
           2-hydroxyhepta-24-diene-1,7-dioate isomerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 257

 Score =  141 bits (342), Expect = 1e-32
 Identities = 77/209 (36%), Positives = 115/209 (55%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+C+G NY DH EE     P+ P +F K P+ V      + +     + +  E EL VV
Sbjct: 59  KVVCIGRNYADHAEEMDSELPDRPMLFLKAPNAVASHGKHLTMPSGKER-IDYEAELGVV 117

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++   V  S A D V GYT   DI   D ++ ++    + GKA D  CPIGP + T +
Sbjct: 118 IGEQCRNVSESGAMDVVAGYTCVNDISNRDDQRREQ--NWVRGKAFDNACPIGPLVATPE 175

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
            +  P++ +++  +NG  KQ S+    I  +P++IA +++ MTL PGD+I TGTP GVG 
Sbjct: 176 HV--PEDASIELRLNGETKQSSSREHLIFSVPELIAEITSYMTLEPGDVIATGTPEGVGP 233

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40
                  ++ GD +  EIE IGT +  V+
Sbjct: 234 -------MEDGDEVEVEIEGIGTLKHSVK 255


>UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rhodobacterales bacterium
           HTCC2654|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rhodobacterales bacterium HTCC2654
          Length = 279

 Score =  141 bits (341), Expect = 2e-32
 Identities = 79/209 (37%), Positives = 112/209 (53%), Gaps = 4/209 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQK----LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499
           +VLC+GLNYKDH  E K     T P+ P +F +F +++    +++ +   VS+ V  E E
Sbjct: 68  QVLCIGLNYKDHRAETKGEVGTTYPDNPIVFMRFATSLAAHGESLPIPK-VSEVVDYEAE 126

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319
           L V+IGK    +  + A  +V GY    DI   DW+   K  Q   GK      P GP +
Sbjct: 127 LAVIIGKGGRYIAKADAMSHVAGYAPFNDISMRDWQM--KGEQWGPGKNFPKSGPFGPVM 184

Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
           VT DE+G+     ++  ++G   Q+S     I  IP +I+  SN + L PGD+I+TGTPG
Sbjct: 185 VTPDEVGDLGETGIRLILDGEVLQESWIKHLIFDIPTLISYCSNFVELRPGDVIVTGTPG 244

Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFE 52
           GVG  R PP  L PG     E++ IG  E
Sbjct: 245 GVGFVRKPPILLAPGKTCVVEVDGIGRLE 273


>UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=3; Dehalococcoides|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Dehalococcoides sp. BAV1
          Length = 253

 Score =  140 bits (339), Expect = 3e-32
 Identities = 79/179 (44%), Positives = 105/179 (58%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ +GLNYK H  E     P+LP IF K  S ++GP D I +K   S+ V  E EL V+
Sbjct: 56  KIIAIGLNYKAHAGEMAEDLPKLPLIFFKNASGIIGPEDNI-IKPGQSERVDYEGELAVI 114

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           I KK   +    AFDY+LGY+   D+ A D +K     Q    K  DTF   GPWI T  
Sbjct: 115 IRKKTRNIKPEDAFDYILGYSCFNDVTARDLQKID--GQWSRAKGFDTFAVCGPWIET-- 170

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           E+ +PQ   ++  +NG  KQ+++T   I  IP I++ +S VMTLLPGDII TGTP G+G
Sbjct: 171 EL-DPQVQLLETYLNGKLKQRTSTADMIFSIPRIVSFISEVMTLLPGDIIATGTPSGIG 228


>UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 250

 Score =  140 bits (338), Expect = 4e-32
 Identities = 80/208 (38%), Positives = 115/208 (55%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVG NY DH  E     P+ P +F K P+TV  P   +    D  + +  E EL  V
Sbjct: 55  KIICVGKNYYDHAMEMGEGVPDRPILFIKAPNTVNHPEGEVSAP-DFVERLDYEGELAFV 113

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           + K+A  V +    DY+LGYT   D+ A D +K+    Q   GK+MD F PIGP +  +D
Sbjct: 114 VKKRAKNVKAEEYGDYILGYTCLNDVTARDIQKSD--GQWSRGKSMDGFAPIGPLV--TD 169

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+    +L ++  +NG   Q S T+ F+ KIP ++  ++  MTL PGD++ TGTP G+G 
Sbjct: 170 EVDG-SDLKIETRLNGKTVQSSRTSLFMTKIPALMEFITASMTLEPGDVVTTGTPAGIGA 228

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                  +QPGDV+  EIE IGT    +
Sbjct: 229 -------MQPGDVVEVEIEGIGTLRNYI 249


>UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation
           bifunctional isomerase/decarboxylase [Includes:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC
           5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2-
           hydroxymuconate Delta-isomerase);
           5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate
           decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5-
           tricarboxylate decarboxylase) (OPET decarboxylase)];
           n=42; Proteobacteria|Rep: 4-hydroxyphenylacetate
           degradation bifunctional isomerase/decarboxylase
           [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2-
           hydroxymuconate Delta-isomerase);
           5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate
           decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5-
           tricarboxylate decarboxylase) (OPET decarboxylase)] -
           Escherichia coli
          Length = 429

 Score =  139 bits (337), Expect = 5e-32
 Identities = 78/212 (36%), Positives = 114/212 (53%)
 Frame = -3

Query: 678 HGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499
           H +  +  +GLNY DH  E +  PPE P +F K P+T+ G N T  ++ +  + +  E E
Sbjct: 220 HPHGTLFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQT-SVRPNNIEYMHYEAE 278

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319
           L VVIGK+A  V  + A DYV GYT+  D    D+ +N     L + K+ D   P+   I
Sbjct: 279 LVVVIGKQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYRPNLRV-KSRDGLTPMLSTI 337

Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
           V  + I +P NL ++  +NG  +Q+  T   I  +P +IA LS  MTL PGD+I TGTP 
Sbjct: 338 VPKEAIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPK 397

Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G+         + PGD +  E+E +G    R+
Sbjct: 398 GL-------SDVVPGDEVVVEVEGVGRLVNRI 422



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 48/156 (30%), Positives = 70/156 (44%)
 Frame = -3

Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430
           PP+    F K  +TV+G  + I       + V+    + +++GK A+KV    A +Y+ G
Sbjct: 31  PPKTAVWFIKPRNTVIGCGEPIPFPQ--GEKVLSGATVALIVGKTATKVREEDAAEYIAG 88

Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
           Y +A D+   +          +  K  D FCPIG  +  S    N  NL +   ING   
Sbjct: 89  YALANDVSLPE---ESFYRPAIKAKCRDGFCPIGETVALS----NVDNLTIYTEINGRPA 141

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
              NT         +++ LS   TL PGD IL GTP
Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTP 177


>UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=13; Campylobacter|Rep: Fumarylacetoacetate
           hydrolase family protein - Campylobacter jejuni subsp.
           jejuni CF93-6
          Length = 292

 Score =  139 bits (336), Expect = 7e-32
 Identities = 77/214 (35%), Positives = 115/214 (53%), Gaps = 6/214 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502
           ++C+G+N+ DH +E      +K    E P  F K  +    P  +I L  DV+  +  E 
Sbjct: 77  IICLGINFLDHAKESAQFKGEKFEEREYPVYFGKRCNQATAPFGSISLHADVTSQLDYEC 136

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322
           EL  ++ K A K+ +  A DY+ GYTI  +I A D +K  K  Q    K+++    +GP+
Sbjct: 137 ELAFILSKDAYKIKAEDAKDYIFGYTIINEISARDLQKRHK--QFYRAKSLEGSTIMGPY 194

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           I + DEI  P  L++K  +N   +Q SNT  FI  I  ++  LS+ M L  G II  GTP
Sbjct: 195 ITSVDEIAYPPELHLKSYVNKELRQNSNTKFFIFDIGYVLEELSSGMLLKAGTIISMGTP 254

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
            GVG+  NPP FL+ GD +   IEN+G    +++
Sbjct: 255 SGVGMGLNPPVFLKKGDEVRCVIENLGELCNKIK 288


>UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=5;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Mesorhizobium sp. (strain BNC1)
          Length = 287

 Score =  138 bits (334), Expect = 1e-31
 Identities = 73/211 (34%), Positives = 115/211 (54%), Gaps = 3/211 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496
           K L +GL++K   +E +   +  PE    FNK  + + GP D + +   VS  +  E EL
Sbjct: 76  KFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVHMPR-VSSELDYEGEL 134

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
            +VIGK+     +S A   + G+ +  D    DW++    + L  GK+ DT  PIGPW+ 
Sbjct: 135 ALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTATL--GKSFDTHGPIGPWLT 192

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           T DE+ +P +L ++  ++G  +Q  NT+  ++   ++IA LS   TL PGDI+ TG+P G
Sbjct: 193 TFDEV-DPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEPGDILATGSPTG 251

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            G Y  PP +L+ G  +  EIE +G  E  +
Sbjct: 252 AGQYMRPPTYLKTGQTVRVEIEGLGHIENMI 282


>UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Actinomycetales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Arthrobacter sp. (strain FB24)
          Length = 290

 Score =  138 bits (334), Expect = 1e-31
 Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 1/202 (0%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           V+ +GLNY  H  E     PE+P +F K  +TV GP D   +   +S+    E+EL VVI
Sbjct: 80  VVGIGLNYAGHAAESGAAVPEVPVVFLKPSNTVAGPFDDAPIP-PLSRKYDWEVELAVVI 138

Query: 483 GKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           G++AS + S   A   V GY +A D+   D++      Q + GK++    P+GPW V + 
Sbjct: 139 GQRASYLKSVDEAAGCVAGYVLANDLSERDYQLPGAAGQWVKGKSLPASTPLGPWFVPAA 198

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           ++ +P  L ++  +NG  +Q S+T   I  +P ++  LS  M L PGD+ILTGTP GV +
Sbjct: 199 DL-DPSALRLRTWVNGELRQDSSTADLIFDVPAVVHHLSQFMVLEPGDVILTGTPEGVAL 257

Query: 126 YRNPPEFLQPGDVITSEIENIG 61
               P +LQ GDV+  E+E +G
Sbjct: 258 SGRFP-YLQDGDVLELEVEGLG 278


>UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Marinomonas sp. MED121
          Length = 298

 Score =  138 bits (333), Expect = 2e-31
 Identities = 76/203 (37%), Positives = 113/203 (55%), Gaps = 1/203 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+C+GLNY DH +E     P+ P +F +  S+++ P     ++  VS  +  E EL ++
Sbjct: 82  KVICLGLNYMDHIKEGGYKVPDYPALFMRSHSSLM-PAQAPMVRPKVSVQLDYEAELMLI 140

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +GK    +  S A DYV GYTI  D    D+++  K  Q   GK  D    IGP IVT D
Sbjct: 141 VGKHGRHIPESKALDYVFGYTIFNDGSVRDYQR--KTHQWTPGKNFDNTGAIGPIIVTPD 198

Query: 306 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           E+      L ++  +     Q +NT++ +  +  +IA +S+  TL PGD+I  GTP GVG
Sbjct: 199 ELPEGAHGLKIETRVGDEILQSANTSEMLWSVARVIAEISSYTTLEPGDLIAMGTPPGVG 258

Query: 129 VYRNPPEFLQPGDVITSEIENIG 61
             R+P  +L+PG+V+  EIE IG
Sbjct: 259 HARSPARWLEPGEVVEVEIEGIG 281


>UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Desulfovibrio|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Desulfovibrio desulfuricans (strain G20)
          Length = 264

 Score =  137 bits (332), Expect = 2e-31
 Identities = 78/202 (38%), Positives = 111/202 (54%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVG+N++DH EE     PE P  F K  S V+G    + L  + S  V  E EL VV
Sbjct: 50  KIVCVGMNFRDHAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAE-SGRVEHEAELGVV 108

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG+ A  +       +V GYT A D+ A D +    +      K  DTF P+GPWI T  
Sbjct: 109 IGRAARNITPEDVPAHVFGYTCANDVTARDLQSRDGLFGRC--KGFDTFAPVGPWIET-- 164

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +  +L ++  +NG  +Q+ +T   +    +I+A +S VMTLLPGD+ILTGTP GVG 
Sbjct: 165 EVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGTPAGVGP 224

Query: 126 YRNPPEFLQPGDVITSEIENIG 61
                  L+ GD +  EI+ +G
Sbjct: 225 -------LEDGDEVRVEIDGVG 239


>UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Acidobacteria bacterium
           Ellin345|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 263

 Score =  137 bits (332), Expect = 2e-31
 Identities = 78/211 (36%), Positives = 111/211 (52%), Gaps = 1/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVG NYK H EE     P+ P IF+K  S ++ P   IK    +S+ V  E EL V+
Sbjct: 63  KIVCVGRNYKAHAEELGHEIPKYPLIFSKPTSAIIAPGADIKRPAKLSQRVDYEGELGVI 122

Query: 486 IGKKASKVDSSH-AFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           IG++   +   H    Y+ GYT+  D+ A D +   K  Q    K  DTFCP+GP  + +
Sbjct: 123 IGRECRHIPEDHDVRSYIHGYTVVNDVTARDLQ--NKDGQWTRAKGFDTFCPVGP--IVN 178

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           D +     + V+  +NG  +Q  NT+ FI  +  I+  +S VMTL PGD+I TGTP GVG
Sbjct: 179 DALDPWTGVEVETRVNGAVRQHGNTSSFIFPLDVILRFISEVMTLFPGDLIATGTPEGVG 238

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
                   +  GDV+   +  IGT    V +
Sbjct: 239 P-------IIAGDVVEVSVAGIGTLRNPVAD 262


>UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Methylobacterium sp. 4-46|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Methylobacterium sp. 4-46
          Length = 288

 Score =  137 bits (331), Expect = 3e-31
 Identities = 73/211 (34%), Positives = 115/211 (54%), Gaps = 1/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+G NY  H  E    P + P +F +  +++V   + + ++   S     E EL  V
Sbjct: 79  KIICIGRNYAAHAREGGAEPLDYPDVFMRGANSLVAHGEPL-IRPRCSDKFDYEGELVFV 137

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +G+KA  V    A   + GY++  +    D+++  + +Q  +GK  D     GP +VT D
Sbjct: 138 VGRKARHVGLDEACGIIAGYSVFNEGSIRDYQR--RATQWTMGKNFDGTGGFGPDLVTPD 195

Query: 306 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           E+ +    L +  ++NG   Q  NT+ FI  +  I+A L+  MTL PGD++LTGTP GVG
Sbjct: 196 ELPDGADGLRLTTTLNGHVMQDGNTHDFIFPVARIVAILTEAMTLEPGDVVLTGTPSGVG 255

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
             RNPP F++PGDV+   IE +GT    V +
Sbjct: 256 YARNPPVFIKPGDVVEVTIEKVGTLRNTVRD 286


>UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;
           Streptomyces ambofaciens ATCC 23877|Rep: Putative
           maleylpyruvate isomerase - Streptomyces ambofaciens ATCC
           23877
          Length = 288

 Score =  136 bits (330), Expect = 4e-31
 Identities = 80/210 (38%), Positives = 113/210 (53%), Gaps = 1/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPF-IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           K++   +NY DH  E + T       +F K  S+V+GP + I L     K    E EL V
Sbjct: 77  KIIGAPVNYLDHKAEMEYTTSVADLGVFLKANSSVIGPGEDILLPYS-DKRTDQEGELGV 135

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIG+ A+ V +  A  +V GYT   DI     E           K+ DTF P+GPW+VT+
Sbjct: 136 VIGRTAAHVSADDALGHVFGYTCVLDITVRSGEDRST------RKSFDTFTPLGPWVVTA 189

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI +P  L+++C + G  +Q++NT   I  + ++IA  S+VMTL PGD+I TGTP GVG
Sbjct: 190 DEIPDPDTLDLRCDVGGTTRQRTNTADLIFGVRELIAYTSSVMTLHPGDVIATGTPAGVG 249

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40
                   L  GD +  +IE +G  E  V+
Sbjct: 250 P-------LAHGDRVVLDIEKVGRLEVGVD 272


>UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1;
           Filobasidiella neoformans|Rep: Mitochondrion protein,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 336

 Score =  136 bits (329), Expect = 5e-31
 Identities = 79/215 (36%), Positives = 126/215 (58%), Gaps = 2/215 (0%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSKAVVC 508
           + G D V+CVG NY++H E  +     + +  IF K  ++++G N  I     V++ +  
Sbjct: 89  LRGRD-VICVGKNYREHAEWVRSLFKLVKYVVIFTKRATSIIGTNQEIYPHPRVTQTLDY 147

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E EL ++IGK   ++    A+DYV G TI  D+ A + +++ K  Q  +GK++DTFCP+G
Sbjct: 148 EGELGIIIGKAGIQISREDAWDYVWGATIINDVTARERQRDHK--QFYIGKSLDTFCPMG 205

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           P+ V S  + + +N+ ++  +NG  +Q +NT+Q I  IP +IA  S  +TL PGD+I TG
Sbjct: 206 PYAVHSSVL-DWRNMMLETRVNGQIRQSANTSQLIFDIPALIATCSMGITLQPGDVISTG 264

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           TP GV +  +  EFL+  DVI   +  +GT    V
Sbjct: 265 TPAGVCL--SSGEFLKHRDVIDISMSGLGTLSNTV 297


>UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_03001459;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001459 - Ferroplasma acidarmanus fer1
          Length = 274

 Score =  135 bits (327), Expect = 8e-31
 Identities = 80/211 (37%), Positives = 116/211 (54%), Gaps = 3/211 (1%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           +LC+GLNYK H  E      PE P +F+K  +   G +  ++    +      E EL V+
Sbjct: 69  LLCIGLNYKSHVSEHAGGKIPETPVVFSKANNAFTGNHSIVQTGNGMHMDY--EGELCVM 126

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK A  V  ++A +YVLGY I  D+ +   +   K +Q  LGK+ D F P GP+I +  
Sbjct: 127 IGKTARNVGEANALNYVLGYFIGNDVSSRLMQY--KTTQFFLGKSFDNFYPNGPYI-SIG 183

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV-- 133
           EI +PQNL ++  +NG  +Q SNT   I  +  +I+ +S  MTL PGD I TGTP GV  
Sbjct: 184 EINDPQNLTIQTRVNGELRQDSNTGLMIFPVNKLISYISQFMTLRPGDCISTGTPAGVIM 243

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
           G+  +  ++L  GD +  +I  +G  ET  E
Sbjct: 244 GMPESNQKWLGKGDKVEVQITGLGKLETTFE 274


>UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Actinomycetales|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 279

 Score =  134 bits (325), Expect = 1e-30
 Identities = 70/211 (33%), Positives = 114/211 (54%), Gaps = 4/211 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNY +H +E     P+ P +F KFP  ++GP D + +    +KA+  E E+ V+
Sbjct: 69  KIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKALDWEGEMAVI 128

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIVT 313
           IGK+A +V  + A +Y+ GY +  D    D++     K  Q   GK+++     GPW+ T
Sbjct: 129 IGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKSAGFGPWMTT 188

Query: 312 SD--EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
            D  E G      +   + G + Q + TN  +     +I  ++++  L  GD+I+TGTPG
Sbjct: 189 PDSFEFGG----ELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDVIVTGTPG 244

Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETR 46
           GVG  RNP  ++  G+ +  EI  +G  E +
Sbjct: 245 GVGHARNPQRYIGDGETVKVEIAGLGFIENK 275


>UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=4; Burkholderiales|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 284

 Score =  134 bits (324), Expect = 2e-30
 Identities = 72/211 (34%), Positives = 115/211 (54%), Gaps = 1/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+LCVGLNY DH +E     P+ P +F + P+++VG +D   ++   S  +  E EL VV
Sbjct: 73  KILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVG-HDCAIVRPLASDTLDYEGELAVV 131

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    +    A  +V GY++  D    +++   K  Q  +GK  D     GP++VT+D
Sbjct: 132 IGKGGKHIAREDALSHVFGYSVFNDGSVREYQF--KSPQWTVGKNFDATGGFGPYVVTAD 189

Query: 306 EIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           E+      L ++  +NG   Q ++T+  ++ +  +IA +S  +TL PGD+I+ GTP G+G
Sbjct: 190 ELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEPGDVIVAGTPSGIG 249

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
             R P   ++ GDV    IE IGT    + +
Sbjct: 250 WAREPKLLMRHGDVCEVSIERIGTLSNPIAD 280


>UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=6; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 292

 Score =  134 bits (323), Expect = 3e-30
 Identities = 76/219 (34%), Positives = 114/219 (52%), Gaps = 4/219 (1%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508
           V G +K+ C+G+NY     E K     P+ P +F + P+++ G    + L  + SK +  
Sbjct: 75  VLGPEKIFCIGVNYAHRNAEYKDNSDLPKYPSVFMRTPASLTGHGQPLLLPPE-SKQLDY 133

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E E+ +VIGK   ++    A  ++ G T   +    DW  + K + +  GK  D    IG
Sbjct: 134 EGEIGIVIGKAGRRIAKEDAHTHIAGLTCINEGTIRDWLHHGKFN-VTQGKNFDASGAIG 192

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           PWIVT+DE  +  N+ +   +NG  +Q+  T   +     +I+ LS   TL PGDII TG
Sbjct: 193 PWIVTADEFPDFDNIGLTTRVNGEVRQQDTTANLMFPFASLISYLSQFATLNPGDIIATG 252

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFE--TRVEE 37
           TP G GV  +PP FL PGDV+  E++ +G      R EE
Sbjct: 253 TPIGAGVRFDPPRFLVPGDVVEVEVDGVGVLANVVRAEE 291


>UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;
           n=2; Actinomycetales|Rep: Possible fumarylacetoacetate
           hydrolase - Rhodococcus sp. (strain RHA1)
          Length = 281

 Score =  134 bits (323), Expect = 3e-30
 Identities = 82/211 (38%), Positives = 113/211 (53%), Gaps = 3/211 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKF-PSTVVGPNDTIKLKMDVSKAVV-CEIELT 493
           +V+CVGLNYK H  E   TPP  P +F ++ PS  V   D     +  ++A +  E E+ 
Sbjct: 68  RVICVGLNYKAHAAEGGFTPPPYPTLFGRWTPSLSV---DGAPTPVPANEAGLDWEGEVA 124

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
             IG +   VD++     VLGY    D+ A   +  K  +Q  LGK  D   P+GP +V 
Sbjct: 125 AFIGTRLESVDAATGQAGVLGYACFNDLTAR--KAQKLTAQWTLGKNGDRSGPLGP-LVP 181

Query: 312 SDEIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           + E+G+    L V+  +NG   Q  NT   I  + +IIA +S   TL PGDII TGTP G
Sbjct: 182 AGEVGDLSDGLRVQTRVNGTVVQDGNTRDLIFSVGEIIALVSETFTLHPGDIIATGTPEG 241

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           VG  RNPP  L PGD++  EI+ +G   T +
Sbjct: 242 VGYVRNPPWLLGPGDIVEVEIDKLGVLRTPI 272


>UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate
           isomerase related protein; n=3; Archaea|Rep:
           2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related
           protein - Thermoplasma acidophilum
          Length = 250

 Score =  134 bits (323), Expect = 3e-30
 Identities = 69/213 (32%), Positives = 113/213 (53%), Gaps = 3/213 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+    +N++ H +E     P  P+ F KF + +VG N T     ++ K +  E E+ +V
Sbjct: 38  KIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREIEK-LDYEGEIGIV 96

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCPIGPWIV 316
           IGK+  ++    A +Y+ G+TI  D+ A D+   E +      + GKA D   P+GP+IV
Sbjct: 97  IGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALPVGPYIV 156

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           T DEI  P  L ++  +NG  +Q   T   +  +  +I+ +S  +TL PGD+I TGTP G
Sbjct: 157 TRDEIRFP--LKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLITTGTPAG 214

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           V  +    ++L  GD ++  +  IG    R+E+
Sbjct: 215 VAAF-TEAKYLSDGDTVSISVSGIGELVHRIED 246


>UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=2; Microbacteriaceae|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Leifsonia xyli subsp. xyli
          Length = 291

 Score =  133 bits (322), Expect = 3e-30
 Identities = 74/206 (35%), Positives = 111/206 (53%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           +V+ +G NY  H  E KL   +   +F+ +P+++ G   T     D++  V  E EL V+
Sbjct: 83  QVIAIGANYAAHASELKLRSEKAATVFSLWPNSLAGHGGTTSWPGDLATQVDYEAELGVI 142

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK A  V +  A DYV GYT+  DI A D + ++  +Q    K+ D F P GP  VT+D
Sbjct: 143 IGKPARDVLAQDALDYVWGYTVVNDITARDLQFSE--AQWSRCKSFDGFTPNGPVAVTAD 200

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+ +PQ+L +  +++G   Q ++T   +  + +II  LS   T+  G +I TG+PGG G 
Sbjct: 201 EVPDPQDLWLTTNVDGAILQDASTADMVRSVAEIIEFLSRSATIPAGTLISTGSPGGAGY 260

Query: 126 YRNPPEFLQPGDVITSEIENIGTFET 49
            R PP FL     +T  I  IG   T
Sbjct: 261 SRTPPVFLHDRSTVTVSIGGIGYLTT 286


>UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Mesorhizobium sp. BNC1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Mesorhizobium sp. (strain BNC1)
          Length = 307

 Score =  132 bits (320), Expect = 6e-30
 Identities = 86/224 (38%), Positives = 116/224 (51%), Gaps = 23/224 (10%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE----------------QKLTPPELPFIFNKFPSTVVGPNDTIKLKM 532
           + C+G NY DH  E                Q+      P+ F K   +V GP   + L  
Sbjct: 80  IYCIGANYADHIAEMQGGGTNGASVAAERKQQKEDGLKPWFFIKSSHSVCGPETKVALPA 139

Query: 531 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ------ 370
             SK V  E EL VVIG+K+  +   +A   V GYTIA D+ A D  +   + Q      
Sbjct: 140 -TSKKVDWEAELAVVIGRKSRDLTIENALTAVWGYTIANDLSARDLSRRPPLPQGSPFFF 198

Query: 369 -LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 193
                K+ D  CP+GPWIV++ +I +  +L++  SING   QKSNT+Q I  + + +A L
Sbjct: 199 DWTSHKSFDDSCPMGPWIVSASQIVDANDLDIGLSINGQPMQKSNTSQMIFTVAEQVAHL 258

Query: 192 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 61
           S  +TL PGDIILTGTP GVG  RN    L+P D ++  IE IG
Sbjct: 259 SQRITLWPGDIILTGTPAGVGAGRNLS--LKPSDEVSVYIEGIG 300


>UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Planctomyces maris DSM 8797|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Planctomyces maris DSM 8797
          Length = 310

 Score =  132 bits (320), Expect = 6e-30
 Identities = 80/221 (36%), Positives = 116/221 (52%), Gaps = 13/221 (5%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPE----LPFIFNKFPSTVVG-PNDTIKLKMDVSKAVVCEI 502
           K+L +  NY  H EE      E     P++F K PST +  P   +K+       +  E+
Sbjct: 91  KLLLLAGNYSKHIEEGGGKAEERQKTFPYVFMKPPSTTLTHPGQPVKIPEVSPDYIDWEL 150

Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNK--------KISQLLLGKAMD 346
           EL +VIGK    V  + A DYV GYT+  DI    +  N                GK  D
Sbjct: 151 ELGIVIGKSCKGVSEAEALDYVAGYTVINDISDRKFRPNPGRTLREKDTFFDWQHGKWHD 210

Query: 345 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 166
           TFCP+GP +  +D+I +PQ L +K S+NG  +Q ++T + I  +  I+  +S+ + L PG
Sbjct: 211 TFCPMGPCVTPADDIPDPQTLKMKLSVNGNVEQDASTAEMIFPVAAIVEFISSFVQLEPG 270

Query: 165 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           D+I TGTP GVG  +N  +FL+ GDV+ +EI+ IG     V
Sbjct: 271 DVISTGTPSGVGASKN--KFLKNGDVMKAEIDQIGVLTNPV 309


>UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=2; Cystobacterineae|Rep: Fumarylacetoacetate
           hydrolase family protein - Stigmatella aurantiaca
           DW4/3-1
          Length = 257

 Score =  132 bits (319), Expect = 8e-30
 Identities = 78/210 (37%), Positives = 114/210 (54%), Gaps = 1/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVV-GPNDTIKLKMDVSKAVVCEIELTV 490
           KV+C+G NY+ H EE     P  P +F K PST + GP   I+L    S+ V  E EL +
Sbjct: 59  KVVCIGQNYRKHAEEMGKPVPSEPLLFIK-PSTALNGPRSPIRLPK-ASQEVHYEAELGL 116

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIG++    D + A   + G T   D+ A D ++ +   Q    K+ DTF  +GPW VT 
Sbjct: 117 VIGERLKNADEATAARAIWGLTCINDVTARDIQRREV--QHTRAKSYDTFACVGPWAVTG 174

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
               +P +L + C +NG  +Q S T+  +     +++ +S++MTLLPGD++ TGTP GVG
Sbjct: 175 L---SPADLRILCRVNGQVRQDSRTSDMVFNPAQLVSFISHIMTLLPGDLVSTGTPSGVG 231

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40
                   L  GD++  E+E IGT    VE
Sbjct: 232 A-------LAAGDMVEVELEGIGTLANPVE 254


>UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=3; Bacillaceae|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Geobacillus kaustophilus
          Length = 262

 Score =  132 bits (318), Expect = 1e-29
 Identities = 79/202 (39%), Positives = 116/202 (57%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           V+ +G NY    E+  +  P++P  F K  S+VVGP   + +   V + V  E EL VVI
Sbjct: 56  VIGIGANYVASSEQLPVELPDIPVFFFKPSSSVVGPEAEVVIPSGVGE-VKFESELAVVI 114

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304
           GK+A +V     + Y+ GYT+A D+ A  +          +GK+ DTF P+GP I T  E
Sbjct: 115 GKEAKQVSEEDVWSYIFGYTVANDVTAPQFFHPD--GHWTIGKSFDTFTPLGPVIET--E 170

Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124
           + +P+ ++VK  +NG +KQ S+T   I  I  +I+ LS+VMTL PGD+ILTG+P G    
Sbjct: 171 L-DPRAVSVKARVNGEEKQNSSTKLMIISISKMISYLSHVMTLQPGDVILTGSPVGA--- 226

Query: 123 RNPPEFLQPGDVITSEIENIGT 58
               E + PG VI  +++ IGT
Sbjct: 227 ----ELVGPGTVIECDVDGIGT 244


>UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Comamonas testosteroni KF-1
          Length = 286

 Score =  132 bits (318), Expect = 1e-29
 Identities = 72/215 (33%), Positives = 114/215 (53%), Gaps = 6/215 (2%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508
           +K++C   NY DH +E      Q+    E P     + S        ++    VS ++  
Sbjct: 72  EKIVCAVRNYMDHHQEVLAAGMQRELSEEPPIFLRVWRSQTAHQGPIVR--PHVSDSLDW 129

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E EL V+IG+    +  + A++++ GY+   D    +W+ + K  Q+  GK  ++    G
Sbjct: 130 EGELAVIIGQGGRDIAEADAWEHIAGYSCYNDASVREWQFHAK--QIASGKNFESTGAFG 187

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           PW+VT+DEI   + L ++  +NG   Q S+T   I  IP +IA  S + TL+PGD+I+TG
Sbjct: 188 PWMVTADEISPGRELKLETRLNGAVVQSSHTGHMIFSIPRLIAYASTIFTLVPGDVIITG 247

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           TP GVG  + P +F++ GDV+  EIE IG     V
Sbjct: 248 TPAGVGWSKKPQQFMKAGDVVEVEIEAIGLLRNPV 282


>UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;
           Pezizomycotina|Rep: Contig An05c0060, complete genome -
           Aspergillus niger
          Length = 290

 Score =  131 bits (316), Expect = 2e-29
 Identities = 79/214 (36%), Positives = 112/214 (52%), Gaps = 7/214 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKL-KMDVSKAVVCEIELTV 490
           + C+GLNY DH +E  L  PE+P +F K  S ++GP   +I + K         E EL V
Sbjct: 76  IRCLGLNYIDHAKEANLALPEVPILFTKPRSALIGPYPASISVPKCAQDGTSDYESELCV 135

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG-----P 325
           VIG+    +   +A DYVLGYT + D+ A   +     +Q    K +D  CPIG     P
Sbjct: 136 VIGRTGRDIPEENALDYVLGYTASNDVSARTLQM--ATAQWSFSKGLDESCPIGIDRTGP 193

Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
            +V+   I +PQ L ++   NGV  Q  +T   I  I   I+ LS   TL  G I LTGT
Sbjct: 194 VLVSPSVIKDPQTLRIQGIHNGVVVQDGHTKDMIFSIKRQISYLSQGTTLEAGTIFLTGT 253

Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           P G+G +++P + L+ GD  +  I+ IGT   +V
Sbjct: 254 PAGIGYFKSPRDVLKDGDEFSVYIDKIGTLTNKV 287


>UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=8; Desulfuromonadales|Rep:
           Fumarylacetoacetate hydrolase family protein - Geobacter
           sulfurreducens
          Length = 218

 Score =  130 bits (314), Expect = 3e-29
 Identities = 71/211 (33%), Positives = 113/211 (53%), Gaps = 2/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+LC+G NY +H +E     P+ P +F K  + V+G  +TI +    S+    E EL ++
Sbjct: 17  KILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIP-SYSRECHHEAELALL 75

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 313
           IGK    +    A ++V GY +A D+   D   E  KK     + K  DT CP+  + V 
Sbjct: 76  IGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSF-VP 134

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           +D + +P +L++   +NG  +Q  +++  IH+IP I++ +S V TL PGD+ILTGTP GV
Sbjct: 135 ADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTLEPGDVILTGTPAGV 194

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
           G        L  GD + +E+  +      V+
Sbjct: 195 GP-------LAAGDAVEAEVVGVAAIRVTVK 218


>UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 291

 Score =  130 bits (314), Expect = 3e-29
 Identities = 77/215 (35%), Positives = 122/215 (56%), Gaps = 7/215 (3%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPEL---PFI-FNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499
           K++    N+K+H +E K         P+I F +    +VGP D I+    ++K +  E+E
Sbjct: 68  KLIHTAGNFKEHEDESKRVGWSHNVGPWIVFMQNVDAIVGPEDGIRYPDHLTKELDYELE 127

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL-LGKAMDTFCPIGPW 322
           L+VVI +   +     A +YV GY I  D+ A D ++++  S +    K +D+FCPIGPW
Sbjct: 128 LSVVINQDVGEFAPEDAMNYVAGYVIFNDVTARDIQRDEMKSGVFGFCKGIDSFCPIGPW 187

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           IVT+DEI NP +L ++  +NG  +Q+S++++    IP+I+AR S  +    GDI+ TGT 
Sbjct: 188 IVTADEIPNPHDLKMELRVNGEPRQESHSSRMWTTIPEILARYS-PLGYSAGDIVTTGTV 246

Query: 141 GGVGVYRNPPE--FLQPGDVITSEIENIGTFETRV 43
            GV  +R   E  +L+ GD +  E+E IG     V
Sbjct: 247 SGVAGFRVDAEDYYLRVGDSVECEVEKIGVLRNTV 281


>UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD -
           Pseudomonas abietaniphila
          Length = 293

 Score =  130 bits (313), Expect = 4e-29
 Identities = 80/211 (37%), Positives = 113/211 (53%), Gaps = 1/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           +V  VGLNY  H +    T PE P  + K  S +VG +D I+    ++  +  E+EL  V
Sbjct: 69  RVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYPA-LTAQLDYEVELVAV 127

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           I +     D   A   +LGYT   DI A D  K      LL  KAMD   P+GPW+VT D
Sbjct: 128 IARALG--DEPCASACLLGYTCGNDISARDAGKRIGRLDLLTQKAMDRTTPVGPWVVTLD 185

Query: 306 EIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           EIG  Q +L+++ S+N   +Q  NT Q +  I +++  +   +TL PGD++ TG+  GVG
Sbjct: 186 EIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARITLQPGDLVFTGSTHGVG 245

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           +      FLQPGD +   IE IG+   RV +
Sbjct: 246 L--EDGRFLQPGDRVEVRIEGIGSMSNRVSQ 274


>UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate
           isomerase; n=1; Thermoplasma volcanium|Rep:
           2-hydroxyhepta-2,4-diend-1,7-dioate isomerase -
           Thermoplasma volcanium
          Length = 268

 Score =  130 bits (313), Expect = 4e-29
 Identities = 71/211 (33%), Positives = 112/211 (53%), Gaps = 3/211 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+    +N++ H  E     P  P+ F KF + +V  N  ++    + K +  E E   V
Sbjct: 61  KIFLPAVNFRSHSAESDTRFPPKPYFFTKFSNALVANNSELRTPGTIKK-LDYEGETGAV 119

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCPIGPWIV 316
           IGKK   + +  A+D + G+TIA D+ A D+   E +      + GKA D   P+GP+I 
Sbjct: 120 IGKKCYNIPAEDAYDCIFGFTIANDLSARDFQFPEMHPYGYNWVQGKAFDGALPVGPYIT 179

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           T DEI  P  L ++  +NG  +QK  T+  +    D+I+ LS  +TL PGDII +GTP G
Sbjct: 180 TKDEIQFP--LEIETKVNGETRQKGTTDDMVFSFQDLISTLSQNITLEPGDIITSGTPAG 237

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           V  + +   +L+ GDVI   + ++GT   ++
Sbjct: 238 VAAF-SEKLYLKSGDVIEISVSSLGTLMNKI 267


>UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Archaeoglobus fulgidus|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Archaeoglobus fulgidus
          Length = 324

 Score =  129 bits (312), Expect = 5e-29
 Identities = 73/190 (38%), Positives = 106/190 (55%), Gaps = 3/190 (1%)
 Frame = -3

Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424
           ++P  +   P +V+GP + + +    ++ +  E+E  +V+GK+   V    A DYVLGYT
Sbjct: 134 QVPVGYKMNPYSVIGPEEPV-IWPSFTQILDYELEFGIVVGKRGKNVSKEDAMDYVLGYT 192

Query: 423 IAQDIGATDWEKNK-KISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQ 253
           I  DI A D E  + K   L  L  K  D   P+GP IVT DEI +P NL +   +NG  
Sbjct: 193 IVNDISARDMEFIELKAMPLGPLKSKDFDNATPMGPCIVTKDEIKDPHNLKMVARVNGEV 252

Query: 252 KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 73
             +++T     KIPD+IA LS   T+ PG ++L+GTPGG G   +  + L+PGDV+  EI
Sbjct: 253 WSEASTKDMHWKIPDLIAHLSKDQTIHPGTVMLSGTPGG-GCGMHVGKLLKPGDVVELEI 311

Query: 72  ENIGTFETRV 43
           E IG     +
Sbjct: 312 EGIGVLRNPI 321


>UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Halorubrum lacusprofundi ATCC
           49239|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Halorubrum lacusprofundi ATCC 49239
          Length = 304

 Score =  129 bits (312), Expect = 5e-29
 Identities = 71/205 (34%), Positives = 109/205 (53%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+G NY DH  E     P+ P +F K P+ +    D I +     + +  E E+ VV
Sbjct: 106 KIVCIGRNYADHAAELDNDVPDRPLLFLKPPNALASHGDEITVPAGKDR-IDWEAEIAVV 164

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++   VD+  A D V G+T   D+   D +  ++    + GKA D   P+GP + T D
Sbjct: 165 IGEQCKDVDADDAMDVVAGFTCMNDVSNRDDQDREQ--NWVRGKAFDGAAPLGPVMATPD 222

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           E+  P + +V+  +NG  KQ S+ +  +  +P +I  ++  +TL PGD+I TGTP GVG 
Sbjct: 223 EV--PADASVELRVNGETKQSSDRSYLMFDVPTLIEEITTYLTLEPGDVISTGTPEGVGA 280

Query: 126 YRNPPEFLQPGDVITSEIENIGTFE 52
                  L  GD +  EIE +GT E
Sbjct: 281 -------LSDGDTVEVEIEGVGTLE 298


>UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase-related protein; n=4; Deinococci|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase-related protein - Deinococcus radiodurans
          Length = 250

 Score =  128 bits (309), Expect = 1e-28
 Identities = 78/209 (37%), Positives = 111/209 (53%), Gaps = 3/209 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496
           K++CVG NY DH  E      +LP    IF K P+ +  P  T++     S+    E EL
Sbjct: 52  KIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGTVEYP-SWSENFHFEGEL 110

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
            +VIG++A  + +  A   VLGYT   D+ A D +K     Q    KA D FCP+GPW+V
Sbjct: 111 ALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQKTDL--QWFRAKAADRFCPLGPWLV 168

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           T  +   P ++ V+  +NG  +Q   T+  I  +  I+  L+  +TL PGD++LTGTP G
Sbjct: 169 TQFD---PSDVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTRFVTLEPGDVVLTGTPEG 225

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFET 49
           VG        LQ GD +  E++ IG  ET
Sbjct: 226 VGP-------LQRGDRVEVEVDGIGVLET 247


>UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Leptospirillum sp. Group II UBA|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Leptospirillum sp. Group II UBA
          Length = 267

 Score =  128 bits (309), Expect = 1e-28
 Identities = 76/203 (37%), Positives = 113/203 (55%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ VGLNY+ H  E     PE P +F K  S ++ PN  I+L   +S+ V  E E+ +V
Sbjct: 60  KIIAVGLNYRAHGNEMGKPLPEEPLLFMKATSALLPPNGEIRLPR-MSRRVDFEGEIALV 118

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +GKKAS +       +V G T A D+ A D +K  K  Q    K+ DTFCP+GP I+T  
Sbjct: 119 MGKKASGISPEEVPLFVYGITCANDVTARDLQK--KDVQYTRAKSFDTFCPLGPVILTG- 175

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
               P +  ++  +NGV +Q++  +  I     +++ +S VMTL PGD+ILTGTP GVG 
Sbjct: 176 --ALPDDRRLRTEVNGVVRQEARASDMIFDPLTLVSFISQVMTLEPGDVILTGTPSGVGP 233

Query: 126 YRNPPEFLQPGDVITSEIENIGT 58
                  L P D ++  +E +G+
Sbjct: 234 -------LSPMDRVSVSLEGVGS 249


>UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6;
           Pezizomycotina|Rep: RIB40 genomic DNA, SC005 -
           Aspergillus oryzae
          Length = 299

 Score =  128 bits (308), Expect = 2e-28
 Identities = 75/213 (35%), Positives = 109/213 (51%), Gaps = 8/213 (3%)
 Frame = -3

Query: 657 CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND--TIKLKMDVSKAVVCEIELTVVI 484
           CVGLNY  H +E    PP  PFIF K P+T V  +    +  ++  +     E EL ++I
Sbjct: 85  CVGLNYAKHIKEAGRKPPPFPFIFFK-PNTCVHDHGKPVVIPRIAQNDQADYEGELCLII 143

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGKAMDTFCPIGPWIV 316
           GK A  V   HA +YV  YT   DI +   +++      + Q    K  DTF P+GP +V
Sbjct: 144 GKDAKDVSPEHALEYVAAYTAGNDISSRKLQRDPAYAGVVPQWGFSKGFDTFAPLGPVLV 203

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
            + EI +P  L++K  ++G  +Q       +     +I+ LS   TL  G +I+TGTPGG
Sbjct: 204 AASEIPDPSQLHLKTIVDGEVRQDETVGDLLFDCKYLISYLSQGTTLQKGSVIMTGTPGG 263

Query: 135 VGVYR--NPPEFLQPGDVITSEIENIGTFETRV 43
           +GV     PP++L PG  +  +I  IGT    V
Sbjct: 264 LGVGAGFKPPKWLVPGTQMDVQISQIGTLRNNV 296


>UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Marinomonas sp. MWYL1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Marinomonas sp. MWYL1
          Length = 245

 Score =  127 bits (307), Expect = 2e-28
 Identities = 73/212 (34%), Positives = 112/212 (52%)
 Frame = -3

Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           N+K L   L  K   E+  + PP+ P +  K  +T +G   +IKL  D   AV     L 
Sbjct: 43  NNKALAKSLE-KAFNEKPHVQPPKTPVLHIKTDNTHIGYGKSIKLPSDKG-AVFAGPSLG 100

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           +VIGKK ++VD+S+A D V G+T+  ++   +    +   +    K  DTFCPIGPW V 
Sbjct: 101 IVIGKKTTRVDASNALDCVAGFTVVNEVSLAETSFYRPAVK---AKCRDTFCPIGPWSVD 157

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
              +  P  L++K  IN     ++NT+Q I+ + +I++ +S+ MTL  GDII+ GTP   
Sbjct: 158 KSAVSTPNKLSIKTFINDALVHETNTDQLIYSVEEIVSYISSFMTLEAGDIIIAGTP--- 214

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
              R     + PGD +  +IE +G     VE+
Sbjct: 215 --ERTADLAINPGDSVMIDIEGVGRLVNPVEQ 244


>UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 285

 Score =  127 bits (307), Expect = 2e-28
 Identities = 70/212 (33%), Positives = 115/212 (54%), Gaps = 4/212 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTP---PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496
           KV+C+GLNY  H  E        PE P +F ++PST+      I +  D  + +  E E+
Sbjct: 68  KVICIGLNYLKHVAEGSYGAEPLPEFPTLFARWPSTLTVDGAQIPVPTD-EEGLDWEGEV 126

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
              +G++ S   +  A D V+GY+   D+ A      K  SQ +LGK  D   P+GP +V
Sbjct: 127 VAWVGRELSCATADEALDAVVGYSTFNDVTAR--RAQKITSQWILGKNADRSGPLGP-LV 183

Query: 315 TSDEIGNPQN-LNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
            + ++G+ ++ L V+  +NG   Q ++T++ ++ + + +A +S  +TL PGD++ TGTP 
Sbjct: 184 PAHDVGDLRDGLRVRTRVNGTTVQDASTDEMVYTVGETLAHISRTLTLRPGDLLATGTPS 243

Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           GVG  R P   L PGD +  E+E +G     +
Sbjct: 244 GVGYARTPAWLLHPGDHVEVEVEKLGVLRNTI 275


>UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albicans
           IPF5534 5-oxo-1; n=1; Debaryomyces hansenii|Rep: Similar
           to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1 -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 289

 Score =  127 bits (307), Expect = 2e-28
 Identities = 74/212 (34%), Positives = 109/212 (51%), Gaps = 4/212 (1%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           V C+G+NYK+H     + PP  P +F K  ++V   N+ I + +        E EL VVI
Sbjct: 79  VKCIGMNYKEHLMGI-IEPPPYPQLFYKPRTSVADQNEDIPIPLFAQNTCDYEGELCVVI 137

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDW----EKNKKISQLLLGKAMDTFCPIGPWIV 316
           GK    ++   A  YV GY    D+ A DW    E   K+ QL   K+ D + P+GP IV
Sbjct: 138 GKTGKNINEEDALSYVAGYVSGNDLSARDWQYFPEYAGKVPQLGFSKSFDRYAPLGPAIV 197

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           +S  I +P  L ++  ING  +Q   T+  +  I  IIA +S   TL  G +I+TGTP G
Sbjct: 198 SSKIIKDPHALQLQTRINGDLRQNCGTDDLLFGISRIIAFISQETTLEQGTVIMTGTPNG 257

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
            G      ++L+ GD++   I+ IGT   + +
Sbjct: 258 CGGIDG--KYLKDGDLVEVTIDQIGTLSHKTK 287


>UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Methanosphaera stadtmanae (strain DSM
           3091)
          Length = 256

 Score =  127 bits (307), Expect = 2e-28
 Identities = 77/203 (37%), Positives = 111/203 (54%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNYKDH +E  +  P+ P +F K  ++V+  N  I +    +  +  E EL +V
Sbjct: 64  KIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAI-IYPSTTNMLDFEGELGIV 122

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           I +K S  D+       + YTI  D+ A D +   K  Q    K+ DTFCP GP +VT  
Sbjct: 123 ILEKVSPCDNGTCN---VAYTIVNDVTARDLQS--KDGQWTRSKSYDTFCPCGPVVVTGI 177

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +     NLN+K  +N   KQ+SNT   I    +++  +SN+MTL PGDII +GTP GVG 
Sbjct: 178 D---SSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVG- 233

Query: 126 YRNPPEFLQPGDVITSEIENIGT 58
                  L  GD +  EI+ +G+
Sbjct: 234 ------HLDVGDTVVVEIDEMGS 250


>UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Mesorhizobium sp. (strain BNC1)
          Length = 293

 Score =  126 bits (303), Expect = 7e-28
 Identities = 74/210 (35%), Positives = 113/210 (53%), Gaps = 7/210 (3%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFI-------FNKFPSTVVGPNDTIKLKMDVSKAVV 511
           +KV+    NY  H +E K     +          F K  S++ GP D I L     + V 
Sbjct: 77  NKVVAFPANYHAHIDEMKAGSGLISNFAAAGQGFFLKANSSLSGPADPIVLPNLDGREVH 136

Query: 510 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 331
            E EL V+IGK+   +   +A  +V GY+   D      E+       ++ K+ DTFCP+
Sbjct: 137 HESELAVIIGKRGRNIPRENALQHVFGYSCLIDAVVRGKEER------VMRKSYDTFCPL 190

Query: 330 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151
           GPW+VT++E+ +P N++++ ++NG  +QK+NT   I  +P++IA  S+VMTL PGDII +
Sbjct: 191 GPWLVTAEEVPDPANIDIELTVNGEVRQKANTRALIVDVPEMIAMASSVMTLEPGDIIAS 250

Query: 150 GTPGGVGVYRNPPEFLQPGDVITSEIENIG 61
           GTP GVG        + PGD +   I  +G
Sbjct: 251 GTPSGVGP-------MLPGDAVCITIAGVG 273


>UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14;
           Dikarya|Rep: Mitochondrion protein, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 311

 Score =  126 bits (303), Expect = 7e-28
 Identities = 77/214 (35%), Positives = 114/214 (53%), Gaps = 5/214 (2%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG---PNDTIKLKMDV-SKAVVCEIEL 496
           + C+GLNY +H +E  L  P++P +F K PST +    P+ TI  K  V S +   E E+
Sbjct: 99  IRCIGLNYVNHAKEVNLPMPDIPTLFMK-PSTSLADPFPSPTIIPKAFVASNSADFESEV 157

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
             VIGK A  V    A DYVLG+T A D+ + + +  +  SQ    K+ D  CPIGP +V
Sbjct: 158 AFVIGKDAKNVSEEEALDYVLGFTAANDVSSREAQFAQ--SQWCYSKSFDGACPIGPALV 215

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
             ++     ++ ++ S+NG   Q S  +  I  +P I++ LS   TL  G II+TGTP G
Sbjct: 216 NKNQANKFSDVKIEGSLNGKTVQSSRLDDLIFSVPKIVSFLSQGTTLPAGTIIITGTPAG 275

Query: 135 VGVYRNPPEFLQPGDVITSEIEN-IGTFETRVEE 37
           VG    P   L+ GD     + + +GT   ++ E
Sbjct: 276 VGWSSTPRITLKDGDEFRVFVSHGVGTLINKIVE 309


>UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3;
           Eukaryota|Rep: Mitochondrion protein, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 228

 Score =  126 bits (303), Expect = 7e-28
 Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 4/183 (2%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC--EIELT 493
           K++ +G NY DH +E     P+ PF F K  S+ + P++     +++ + V+   E+EL 
Sbjct: 10  KIVAIGRNYADHAKELGNAIPKEPFFFLKPTSSYLVPDNG---PVEIPRGVIVHHEVELG 66

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 319
           VVIGK    +  S AFD+V GY++A D+ A + +   K   L     K  DTFCPIGP+I
Sbjct: 67  VVIGKNGRDISPSAAFDHVAGYSLAVDMTARNVQDKAKAKGLPWSAAKGFDTFCPIGPFI 126

Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
                I +P  + +  S+NG  KQ   T+  I  IP +IA +S +M L  GD++LTGTP 
Sbjct: 127 -PKHFIADPTKVGLHFSVNGTVKQSGLTSDMIFDIPQLIAFVSGIMKLEEGDLVLTGTPS 185

Query: 138 GVG 130
           GVG
Sbjct: 186 GVG 188


>UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5;
           Eukaryota|Rep: Uncharacterized protein ZK688.3 -
           Caenorhabditis elegans
          Length = 214

 Score =  125 bits (302), Expect = 9e-28
 Identities = 70/180 (38%), Positives = 101/180 (56%), Gaps = 2/180 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVG NYKDH  E     P+ P +F K  ++ +   + I         +  E+EL VV
Sbjct: 13  KIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPIVAPPGCQN-LHQEVELGVV 71

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 313
           I KKAS++  S A DY+ GYT+A D+ A D+  E  K  +   L K+ D  CPIG ++  
Sbjct: 72  ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           SD I NP ++ + C ING  +Q+  T+  I  IP ++   +   TL  GD++LTGTP GV
Sbjct: 132 SD-IPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGV 190


>UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4;
           Actinomycetales|Rep: Maleylpyruvate isomerase -
           Rhodococcus sp. (strain RHA1)
          Length = 275

 Score =  125 bits (301), Expect = 1e-27
 Identities = 66/203 (32%), Positives = 107/203 (52%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVGLNY +H +E     PE P +F KF   + GP D + +    +  +  E EL  V
Sbjct: 69  KIICVGLNYANHIQEMGRDLPEYPTLFAKFKEALTGPYDDVIVPSYAAAQLDWEGELAFV 128

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +GK+A +V  + A  Y+ GY++  D    D++   +  Q   GK  +     GP++ T+D
Sbjct: 129 VGKQAYQVPEADAEQYIAGYSVMNDYTMRDYQ--YRTLQWDQGKTFEKTSGFGPFLTTTD 186

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
                  L  K  + G   Q + T+  +     ++  +S+++TL PGD+++TGTPGGVG 
Sbjct: 187 SYTFGGTLVTK--LEGQVVQSTTTDDLVFTPARLVEYISHIVTLQPGDVVITGTPGGVGH 244

Query: 126 YRNPPEFLQPGDVITSEIENIGT 58
            R P  ++Q G  +   IE +GT
Sbjct: 245 ARKPGLYIQDGQTVEVTIEGLGT 267


>UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Nocardioides sp. JS614|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 269

 Score =  124 bits (300), Expect = 2e-27
 Identities = 79/210 (37%), Positives = 107/210 (50%), Gaps = 1/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+ +G NY  H  E     P  P +F K  ++V+GP D I         +  E EL VV
Sbjct: 68  KVVGIGRNYAAHAAELGNDLPTEPLMFLKPNTSVIGPGDPIFYPPQTQN-LHYEGELAVV 126

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS- 310
           IG+    V    A D + GYTI  D+ A D +++    Q    K  D+FCP+GPWI T  
Sbjct: 127 IGRICRDVPPEQATDVIHGYTIGNDVTARDLQRSDV--QFTRAKGFDSFCPLGPWIETDL 184

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           D     +  +V+  +NG   Q  +T   I  IP +IA +S+VMTLLPGD+ILTGTP GVG
Sbjct: 185 DPHDFAEGRSVQTHLNGDLVQDGSTKDLIFDIPTLIAYVSSVMTLLPGDVILTGTPEGVG 244

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40
                   +  GD +   I  +GT    V+
Sbjct: 245 P-------MDVGDEVEVSIAGLGTLTNPVK 267


>UniRef50_Q4JXJ3 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Corynebacterium jeikeium (strain K411)
          Length = 272

 Score =  124 bits (299), Expect = 2e-27
 Identities = 67/209 (32%), Positives = 108/209 (51%), Gaps = 1/209 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+ CVGLNY++H  E     P+ P +F K+ S + GP D + +  ++S     E EL V+
Sbjct: 74  KIFCVGLNYREHIAEMGHPIPDHPTLFVKYASALAGPFDEVVVPPELSAQADYEGELAVI 133

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +G+          F  + GYT+  D    DW+   +  Q L GK +D     GPW+V ++
Sbjct: 134 MGE----------FGQIAGYTVMNDFSQRDWQY--RTQQWLQGKNLDRSSGFGPWMVPTE 181

Query: 306 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
                 +   ++  +NG  +Q+ +    + K  D++  +SN  +L PGD+I+TGTP GVG
Sbjct: 182 HFDPIAEGAVLRTWVNGELRQEHSVADLVFKPQDLVDYISNFASLAPGDVIVTGTPEGVG 241

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
               PP++L  GD +   I+ IG    R+
Sbjct: 242 HGMTPPQYLADGDEVRIAIDGIGEICNRI 270


>UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase;
           n=2; Ostreococcus|Rep: Predicted fumarylacetoacetate
           hydralase - Ostreococcus tauri
          Length = 322

 Score =  124 bits (299), Expect = 2e-27
 Identities = 77/223 (34%), Positives = 116/223 (52%), Gaps = 14/223 (6%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508
           + CVG NY +H  E         ++  PE P IF+K  +++     +I  +    K V  
Sbjct: 102 IACVGKNYLEHVGEVDSTMPGISRMDVPEAPIIFSKASTSLNAHLGSIATRG--RKDVDY 159

Query: 507 EIELTVVIGKKASKVDSSHAFD-----YVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 343
           E EL  VIG++   +D   + +     YV+G++IA D+ A + +K  +  Q  LGK+ DT
Sbjct: 160 EGELVAVIGRECRDIDPGMSDEDVVKNYVIGWSIANDVTARELQKTHQ--QWFLGKSGDT 217

Query: 342 FCPIGPWIVTSDEIGNPQNL-NVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 166
            CP+GPW+   D         ++  ++N   +Q+S  +Q I  +  +IA +S   TL  G
Sbjct: 218 HCPLGPWVCCDDGRAPALGAASITTAVNSEIRQRSTVDQLIWSVGALIACISRHQTLRVG 277

Query: 165 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           D +LTGTP GVG   +PP FLQPGD     IE +GT +  V E
Sbjct: 278 DCVLTGTPSGVGAGFDPPRFLQPGDACEVTIEGVGTLKNTVVE 320


>UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE
           ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE; n=19; Proteobacteria|Rep:
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE /
           5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE - Brucella melitensis
          Length = 311

 Score =  123 bits (297), Expect = 4e-27
 Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 2/212 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQK--LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           K++CVG+N+ D  EE K     P  P +F +FP +  G    + ++   S  +  E E+ 
Sbjct: 99  KIICVGVNFPDRNEEYKDGQAAPANPSLFVRFPRSFTGHERPL-MRPPESPQLDYEGEIA 157

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           +VIGK   ++    A D++   T+  +    DW ++ K + +  GK  D    IGPW+V 
Sbjct: 158 IVIGKGGRRIAEKDALDHIAALTLCNEGTIRDWVRHAKFN-VTQGKNFDATGSIGPWLVP 216

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
             +     ++ +   +NG  +Q+  T++ I     II  +S   TL+PGD+I+ GTP G 
Sbjct: 217 YTDESQIADIQLTTRVNGEVRQQDRTSRMIFSFRKIINYVSTFTTLVPGDVIVCGTPTGA 276

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           G   +PP +L+PGDV+  E E IG     + +
Sbjct: 277 GARFDPPIWLKPGDVVEVEAEGIGLLRNTIAD 308


>UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF;
           n=1; Pseudomonas alcaligenes|Rep: Putative
           uncharacterized protein xlnF - Pseudomonas alcaligenes
          Length = 287

 Score =  123 bits (296), Expect = 5e-27
 Identities = 77/219 (35%), Positives = 112/219 (51%), Gaps = 10/219 (4%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTP-----PELPFI-----FNKFPSTVVGPNDTIKLKMDVSKA 517
           K++   +NY DH +E           E+  I     F K  S+ VGP++ I L     + 
Sbjct: 82  KIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVGPDEGISLPAVEGRR 141

Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337
              E+EL +VIGK+  +V    A   V GY I  DI     E           K+ D+F 
Sbjct: 142 FDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRS------YRKSFDSFT 195

Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
            +GPW+VTSD  G+P+ +    S+NG Q+Q +NTN  +  +  II+  S+  TL PGD+I
Sbjct: 196 VMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIISVASHAYTLYPGDVI 255

Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
           LTGTP GVG        ++ GD I++ I+ IG+ E  V+
Sbjct: 256 LTGTPAGVGP-------IKAGDKISASIDRIGSMEVPVK 287


>UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Hyperthermus butylicus DSM 5456|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Hyperthermus butylicus (strain DSM
           5456 / JCM 9403)
          Length = 338

 Score =  123 bits (296), Expect = 5e-27
 Identities = 67/209 (32%), Positives = 110/209 (52%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +K++C+G+NY+ H  E  +  P  P +F K  +++VGP D + +   V   +  E+EL  
Sbjct: 120 EKIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDPVVVH-SVGLKLDGEVELAA 178

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIG  A  +  S A D V G+ +  D+ +   ++   ISQ    K+ DT+ P GP IV  
Sbjct: 179 VIGIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSHDTYAPTGPIIVPR 238

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
             + +  +  ++  ++G+  ++ NT   +H + DI++  S    L+PGDII TGTP G  
Sbjct: 239 HMV-SIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVPGDIICTGTPAGTM 297

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
               P +  +PG V+ +    IG  E RV
Sbjct: 298 PDGKPAKTPEPGSVMRACARGIGCIENRV 326


>UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albicans
           IPF5534; n=2; Ascomycota|Rep: Similar to CA3735|IPF5534
           Candida albicans IPF5534 - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 208

 Score =  121 bits (292), Expect = 1e-26
 Identities = 74/208 (35%), Positives = 105/208 (50%), Gaps = 6/208 (2%)
 Frame = -3

Query: 648 LNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKL-KMDVSKAVVCEIELTVVIGKK 475
           +NY  H +E  L PP  P IF K P T VG  N+ I + K+        E E  VVI K 
Sbjct: 1   MNYMKHIQEGSLPPPPKPQIFYK-PRTSVGDHNEAIAIPKIAQENQCDYEGEFCVVIVKT 59

Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNK----KISQLLLGKAMDTFCPIGPWIVTSD 307
              +    A +YV GY +  D+ A  W+ +      I Q    K+ D + P+GP + ++ 
Sbjct: 60  GKHIKEEDALNYVAGYIVGDDVSARIWQYHPDYSGNIPQWYYSKSFDRYAPLGPALFSTR 119

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
            I NP  L ++  ING  +Q +NT+  +  I  IIA LS   TL  G +I+TGTP GVG 
Sbjct: 120 VIKNPHTLQLQTRINGELRQDANTDDLLFNIQKIIAFLSQGTTLEQGTVIMTGTPSGVGA 179

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                 +L+ GD++   IE IGT   ++
Sbjct: 180 VSG--RYLKDGDLVEISIEQIGTLSHKI 205


>UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation
           bifunctional isomerase : decarboxylase; n=2;
           Bacillaceae|Rep: 4-hydroxyphenylacetate degradation
           bifunctional isomerase : decarboxylase - Oceanobacillus
           iheyensis
          Length = 263

 Score =  121 bits (291), Expect = 2e-26
 Identities = 70/197 (35%), Positives = 103/197 (52%)
 Frame = -3

Query: 627 EEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHA 448
           E+   TPP+ P ++ K  +T +G   TI L   V K  +    L VVIGK A  +   +A
Sbjct: 68  EDPYKTPPKAPILYIKPINTHIGYGMTIPLPEGVEKVSI-GAALGVVIGKPAKNIRKENA 126

Query: 447 FDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCS 268
            DYV GYTI  D+   +    +   +    KA D FCPIGPW++  D I NP  L ++  
Sbjct: 127 LDYVAGYTIVNDVSIPNESYYRPAYK---EKARDGFCPIGPWVLRRDAIENPNELGIRVY 183

Query: 267 INGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDV 88
           ING  KQ++ T+  I  +  ++  +++ MTL  GD++L G P       N P   +  D 
Sbjct: 184 INGEIKQENTTSNLIRSVEQLMEEVTDFMTLYEGDVLLVGVP------ENAP-IAKENDR 236

Query: 87  ITSEIENIGTFETRVEE 37
           +  EI+NIGT   +VE+
Sbjct: 237 VIIEIDNIGTLVNKVEK 253


>UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Gammaproteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           marine gamma proteobacterium HTCC2143
          Length = 223

 Score =  120 bits (290), Expect = 2e-26
 Identities = 75/210 (35%), Positives = 107/210 (50%), Gaps = 2/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CVG NY DH +E     P+ P +F K  +  V     I +  D       E+E+ V+
Sbjct: 23  KIVCVGRNYADHAKELNNPIPDRPLLFIKPSTAAVDMLLPINIPTDRG-CCHHELEMAVL 81

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 313
           IGK++S V S  A D ++G  +  D+   D +   K         KA D  CP+ P+   
Sbjct: 82  IGKRSSSVSSVEAKDAIVGVGLGLDLTLRDLQDELKAKGEPWERAKAFDGSCPLSPFSSV 141

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
            D   + QNLN+    NG  +Q  NT   +  + D+IA +S   TLLPGDIILTGTP GV
Sbjct: 142 GDI--DQQNLNITLLRNGTVQQSGNTRDMLFPVADLIADISRSFTLLPGDIILTGTPAGV 199

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G        L PGD IT+++ ++ T  T +
Sbjct: 200 GP-------LYPGDTITAQLGDLVTVNTTI 222


>UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6;
           Ascomycota|Rep: 2-keto-4-pentenoate hydratase -
           Sclerotinia sclerotiorum 1980
          Length = 241

 Score =  120 bits (288), Expect = 4e-26
 Identities = 70/215 (32%), Positives = 118/215 (54%), Gaps = 5/215 (2%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+C+G NY DH  E   + P+ PF F K PS+++ PN    ++      +  E+EL ++
Sbjct: 20  KVVCIGRNYADHITELNNSKPKQPFFFLKPPSSILPPNGGAVIRPK-GVDLHYEVELALI 78

Query: 486 IGKKASKVDSSH---AFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFCPIGPW 322
           +GK+   ++  +   A+D +  Y ++ D+ A + +   K   L   + K  DTF P+   
Sbjct: 79  MGKQLKNLEPENEKEAYDSIESYAMSIDMTARNAQNEAKKKGLPWDIAKGFDTFLPMSN- 137

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           I++  +I +P N  V  ++N   +QK +T   +++IP I++ +S VMTL  GDI+LTGTP
Sbjct: 138 IISKSQIPDPHNATVWLTVNNEHRQKDSTELMLYRIPRILSDISKVMTLEKGDIVLTGTP 197

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
            GVG  + P + ++ G  +  +    G  E  VEE
Sbjct: 198 KGVGSVK-PGDVMRVGISVGGKELTEGKIEVAVEE 231


>UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2;
           Proteobacteria|Rep: Putative hydratase - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 289

 Score =  119 bits (286), Expect = 8e-26
 Identities = 76/218 (34%), Positives = 113/218 (51%), Gaps = 10/218 (4%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQK----------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517
           KV+   +NYK H +E +          +   E   +F K  S+VVGP+  ++++    + 
Sbjct: 79  KVIAAPVNYKKHLQEAREQVEIHHNNQVAEIEKIGLFLKATSSVVGPSHGVEIQHP-DRR 137

Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337
              E EL  VIGK    +    AFD++  YTI  D+     ++        L K++DT+ 
Sbjct: 138 NDHEAELVAVIGKTGRNIPRERAFDHISAYTIGLDMTVRGPQERS------LRKSIDTYS 191

Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
            +GPW+VT+DEI +PQ L+   ++NG ++QK+NT   +  IP +I   S+  TL PGD++
Sbjct: 192 VVGPWLVTADEIDDPQALDFWLTVNGERRQKANTRDLVLDIPALIEMASSYYTLQPGDLL 251

Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            TGTP GVG   N       GD IT EI  IG     V
Sbjct: 252 FTGTPEGVGPVVN-------GDEITVEIAGIGRMNVAV 282


>UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41;
           Gammaproteobacteria|Rep: Uncharacterized protein ycgM -
           Escherichia coli (strain K12)
          Length = 219

 Score =  119 bits (286), Expect = 8e-26
 Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 2/188 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+CVG NY  H +E     PE P +F K  + +      + +  D   +V  E+EL V+
Sbjct: 18  KVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFG-SVHHEVELAVL 76

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAMDTFCPIGPWIVT 313
           IG    +    H    + GY +A D+   D + K KK  Q     KA D  CP+  +I  
Sbjct: 77  IGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPA 136

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           ++  G+PQN  +  S+NG Q+Q+  T   IHKI  +IA +S   TL  GD++LTGTP GV
Sbjct: 137 AEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGV 196

Query: 132 GVYRNPPE 109
           G  ++  E
Sbjct: 197 GPLQSGDE 204


>UniRef50_Q2S2N6 Cluster: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Salinibacter ruber DSM 13855|Rep: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Salinibacter ruber (strain DSM 13855)
          Length = 220

 Score =  118 bits (283), Expect = 2e-25
 Identities = 61/181 (33%), Positives = 100/181 (55%), Gaps = 2/181 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+LC+G NY DH  E     P+ P +F K  S +V     ++L    S+ V  E+EL  V
Sbjct: 16  KLLCIGRNYADHAAEMDRAVPDEPMVFLKPASALVRSGGAVRLPPQ-SQDVHHEVELVAV 74

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFCPIGPWIVT 313
           +G +   +  S A D+V GY +  D+ A D +   K  +    + K  DTF P+GP I  
Sbjct: 75  VGTEGKNIPRSAALDHVAGYAVGLDMTARDLQAEAKERRHPWSVAKGFDTFAPLGP-IQP 133

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           ++ + + Q+L ++ ++N   +Q+++T   I  + D++   S++ TL PGD++ TGTP GV
Sbjct: 134 AEAVDDVQDLTLRLTVNDETRQEASTRHQIFPVRDLVHYCSHIFTLSPGDLLYTGTPSGV 193

Query: 132 G 130
           G
Sbjct: 194 G 194


>UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer; n=10; Bacteria|Rep:
           5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer - Synechocystis sp. (strain PCC
           6803)
          Length = 276

 Score =  118 bits (283), Expect = 2e-25
 Identities = 72/208 (34%), Positives = 101/208 (48%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ VG NY+ H  E     P  P +F K PS +    + I      S+ V  E EL V+
Sbjct: 59  KIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAADQEEIVYPSQ-SQRVDYEGELAVI 117

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK+   +    A   + GYTIA DI A D ++    SQ    K  D FCP+GPW+V   
Sbjct: 118 IGKQVKDITEEEAASAIWGYTIANDITARDLQRQD--SQWTRAKGFDGFCPLGPWVVR-- 173

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
            I    +L    +     +Q +  +  +   P +++ +S VMTL PGD+ILTGTP G+  
Sbjct: 174 HIDPEAHLETTVNDEETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEGISA 233

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                  LQ GD +  EIE IG     +
Sbjct: 234 -------LQVGDKVEVEIEGIGNLTNTI 254


>UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Gammaproteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Enterobacter sp. 638
          Length = 219

 Score =  118 bits (283), Expect = 2e-25
 Identities = 69/181 (38%), Positives = 95/181 (52%), Gaps = 2/181 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+CVG NY  H +E     P+ P +F K  + +      + L   +  +V  E+EL V+
Sbjct: 18  KVVCVGSNYAKHIQEMGSAVPDEPVLFIKPETALCDIRQPLALPQGLG-SVHHEVELAVL 76

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAMDTFCPIGPWIVT 313
           IG    +    H    + GY IA D+   D + K KK  Q     K  D  CPI  +I T
Sbjct: 77  IGATLRQASEEHVQKAIAGYGIALDLTLRDVQGKMKKAGQPWEKAKGFDNSCPISGFIPT 136

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           +D   +PQN ++   +NG  +Q+ NT   IHKI  +IA +S   TL PGD+ILTGTP GV
Sbjct: 137 ADFKADPQNTSLSLKVNGDIRQQGNTADMIHKILPLIAYMSRYFTLKPGDVILTGTPEGV 196

Query: 132 G 130
           G
Sbjct: 197 G 197


>UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 343

 Score =  117 bits (282), Expect = 2e-25
 Identities = 73/188 (38%), Positives = 99/188 (52%), Gaps = 4/188 (2%)
 Frame = -3

Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418
           PF F K  S+++GP D + +  D S+ +  E+EL VVIGK A +V    A D+V GY + 
Sbjct: 137 PFAFLKPFSSILGPFDDLAVPAD-SEQLDWELELGVVIGKPARRVGRDRALDHVAGYVVV 195

Query: 417 QDIGATDWEKNKKISQLLL----GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
            DI   D      + QL L    GK+     P+GP IV +  + +PQ L +   +NG   
Sbjct: 196 NDISVRDHLYRPDVPQLGLDWVSGKSGPGMLPMGPLIVPAAFVADPQQLMITLKLNGEVM 255

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70
           Q  +T   I  I  +I   S  M LLPGDII TG+P G G +     FL+PGDV+   IE
Sbjct: 256 QHESTADMIFPIARLIEAFSVHMQLLPGDIICTGSPSGNGTHFG--RFLRPGDVMEGTIE 313

Query: 69  NIGTFETR 46
            +GT   R
Sbjct: 314 GLGTQRNR 321


>UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM -
           Pseudomonas abietaniphila
          Length = 289

 Score =  117 bits (281), Expect = 3e-25
 Identities = 73/216 (33%), Positives = 111/216 (51%), Gaps = 5/216 (2%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           ++V+  G NY  H  E  L+ P  P  F K    ++G +D I+    ++  +  E+EL  
Sbjct: 70  NRVVVAGANYAKHLVEFGLSAPSQPVAFLKAYGALIGAHDPIRFP-PLTTELDHEVELVA 128

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKISQ-LLLGKAMDTFCPIGPWI 319
           VIG  +  VD       VLGYT+  D+ A D +++  K I   L   K+ D    +GPW+
Sbjct: 129 VIG--SDDVDLDDPLACVLGYTVGNDVSARDLQRSGPKGIGMDLFAAKSQDKTTGLGPWV 186

Query: 318 VTSDEI--GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
           VT DE+  G+P+ L +   +NG  +Q  NT      + ++IA +    +   GD++ TG+
Sbjct: 187 VTKDELPEGSPK-LRLTLKVNGQMRQDGNTADMTWDVGELIAFVQQRSSFACGDVLFTGS 245

Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           P GVG+      FL PGDV+ + IE IGT    V E
Sbjct: 246 PAGVGM--GTGIFLDPGDVVEASIEGIGTLRNVVGE 279


>UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Corynebacterium|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 268

 Score =  115 bits (276), Expect = 1e-24
 Identities = 81/208 (38%), Positives = 107/208 (51%), Gaps = 6/208 (2%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEE--QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           KV+ +G NY DH  E  +K      P +F K P+ V GP   I++    +K V  E EL 
Sbjct: 62  KVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRIPSFATK-VEFEGELA 120

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           VVIGK    V +      VLG+TI  D+ + D +      Q    K +DTF PIGPWI T
Sbjct: 121 VVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFAD--GQWARAKGIDTFGPIGPWIET 178

Query: 312 SDEIGNPQNLNVKCSI--NGVQ--KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
                +  NL +K  +  +G    KQ SN+NQ I K+ +II  ++  MTLLPGD+I TG+
Sbjct: 179 DINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGS 238

Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIG 61
           P G        E +  GD I  EI  IG
Sbjct: 239 PAGT-------EAMVDGDYIEIEIPGIG 259


>UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;
           Trichocomaceae|Rep: Remark: ORF contains 1 frameshift -
           Aspergillus niger
          Length = 296

 Score =  115 bits (276), Expect = 1e-24
 Identities = 67/215 (31%), Positives = 110/215 (51%), Gaps = 5/215 (2%)
 Frame = -3

Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL-KMDVSKAVVCEI-E 499
           N+ + CVGLNY+ H +E  L  P  P ++ K P+ +  P++TI + +   S     E  E
Sbjct: 64  NNSIYCVGLNYRSHAKEANLNVPANPPVWTKPPAALASPDETIPISRFCASHLPDWEAGE 123

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFCPIGPW 322
           L  V  ++   V    A  Y+LGYT+  D+    ++   +   Q    KA D F PIGP 
Sbjct: 124 LVFVTSRECRDVTPEQASQYILGYTVGNDLSCRFFQLPEQSGGQFFYAKAFDKFAPIGPV 183

Query: 321 IVTSDEIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPD-IIARLSNVMTLLPGDIILTG 148
           +V+ D     + +  +   INGV KQ +   + +   P+ +++ +S   T+    +++TG
Sbjct: 184 LVSPDVFAKTRTSATLVTRINGVVKQDTVIGKDMIFSPERVLSWMSQSTTIPAYTVVMTG 243

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           TP G GV++ P + L+ GD I  EI  +GT +  V
Sbjct: 244 TPAGAGVFQTPRQLLKDGDHIEVEISGLGTLKNVV 278


>UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase
           domain-containing protein 1; n=21; Eumetazoa|Rep:
           Fumarylacetoacetate hydrolase domain-containing protein
           1 - Homo sapiens (Human)
          Length = 224

 Score =  114 bits (275), Expect = 2e-24
 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 2/187 (1%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           ++CVG NY DH  E +      P +F K PST   P  +  L    ++ +  E+EL VV+
Sbjct: 20  IVCVGRNYADHVREMRSAVLSEPVLFLK-PSTAYAPEGSPILMPAYTRNLHHELELGVVM 78

Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           GK+   V  + A DYV GY +  D+ A D   E  KK     L K+    CP+  + V  
Sbjct: 79  GKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAF-VPK 137

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           ++I +P  L +   +NG  +Q+  T+  I  IP II+ +S ++TL  GDIILTGTP GVG
Sbjct: 138 EKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVG 197

Query: 129 VYRNPPE 109
             +   E
Sbjct: 198 PVKENDE 204


>UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Serratia proteamaculans 568
          Length = 287

 Score =  113 bits (273), Expect = 3e-24
 Identities = 74/220 (33%), Positives = 110/220 (50%), Gaps = 10/220 (4%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEE----QKLTPPELPF------IFNKFPSTVVGPNDTIKLKMDVSKA 517
           K++   +NY+DH  E    Q++   ++        +F K  S++ GPN+ I L +   + 
Sbjct: 79  KIVAAPINYRDHIAEANADQQINHGKVYTDISEYGLFLKANSSLCGPNEIIPLPIP-GRR 137

Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337
              E+EL V+IG++A  +    A + V GY I  D+     E           K+ D F 
Sbjct: 138 TDPEVELAVIIGQRARNLPVDQALEAVFGYAIGIDMTVRGSEFPS------FRKSADGFS 191

Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
            +GPWIVT DEIG+P  L++   +NG  +Q SNT   I+ +  +IA  S + TL PGD+I
Sbjct: 192 VLGPWIVTPDEIGDPNTLDLSIRVNGQLRQHSNTRHLIYNVQRLIAYASAMFTLWPGDVI 251

Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
            TGTP GV         +Q GD I   IE IG     + +
Sbjct: 252 YTGTPSGVSA-------IQAGDRIEVSIERIGAMSVTIAD 284


>UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Solibacter usitatus Ellin6076|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Solibacter usitatus (strain Ellin6076)
          Length = 252

 Score =  113 bits (271), Expect = 5e-24
 Identities = 73/209 (34%), Positives = 101/209 (48%), Gaps = 1/209 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+L VGLNYK H   +    P  P +F K  S +  P D I+L  D +  V  E E+ VV
Sbjct: 56  KILAVGLNYKSHLGSRP--QPAHPEMFYKPISALQNPGDPIELPRDATD-VHSEGEMVVV 112

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLLLGKAMDTFCPIGPWIVTS 310
           +G          A D V G T   D+    W+   KK  Q    K  DTF P+GP IV+ 
Sbjct: 113 VGGYLRNASVDEAADAVFGVTCGNDVSDRSWQHGEKKDLQWWRAKGSDTFAPLGPAIVSG 172

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
            + G    L ++  ING   QK  T+  I  IP +++ +S  +TL PGD++ TGTPG   
Sbjct: 173 VDYGK---LLLQTRINGETVQKQFTSDLIFDIPTVLSWISGWVTLFPGDLVYTGTPGNT- 228

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
                   + PGD++  E+E +G     V
Sbjct: 229 ------RKMSPGDLVEVELEGVGVLSNPV 251


>UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 312

 Score =  112 bits (270), Expect = 7e-24
 Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 8/218 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPEL-------PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505
           V+C+G+NY +H +E      E+          F+K  +     N  I L  ++++ +  E
Sbjct: 98  VICLGINYLEHAKESAAYKNEIFDQKRENAVYFSKRVNYATPHNAPIPLHSNLTQKLDYE 157

Query: 504 IELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           +EL VV+G    K  +     D + GYTI  DI + D ++  K  Q  +GK+++   P+G
Sbjct: 158 VELGVVLGSHLYKPKNMQEVIDSIFGYTIINDISSRDIQQKHK--QWYMGKSLEGSLPMG 215

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           P IV++  I + QNL +K  +NG  +Q S+T+  I  I   +  LS+   L    II  G
Sbjct: 216 PCIVSARSI-DAQNLAIKSYVNGELRQDSHTSLMICNITAALYELSHYCMLQAASIISMG 274

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 34
           TP GVG+  NPP FL   D I  EI++IG+    V ++
Sbjct: 275 TPSGVGMGFNPPRFLSNNDEIVCEIQHIGSLRNVVIDY 312


>UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Sphingomonas wittichii RW1
          Length = 329

 Score =  112 bits (269), Expect = 9e-24
 Identities = 66/190 (34%), Positives = 96/190 (50%), Gaps = 4/190 (2%)
 Frame = -3

Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418
           P++F K  +TV G NDT+ L  + +K    E+EL VVIG+   ++    A ++V GY I 
Sbjct: 139 PYVFTKPITTVAGANDTLILPANTTKPD-WELELAVVIGRGGIRIPREAAMEHVAGYAIV 197

Query: 417 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
            D+ A D         L    L  K  + F P GP++V +  I +P  L ++ S+ G   
Sbjct: 198 NDVSARDLIPRTDYKLLGTDWLRSKGQEGFLPFGPYMVPARFIADPYALRIRLSVEGQMM 257

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70
           Q   T   +  I   I  +S    LLPGD+I TG+P G G + N   FLQ GD++  EI+
Sbjct: 258 QDETTADMMFDIARQIEYISRYSRLLPGDVICTGSPAGNGTHYN--RFLQDGDLMIGEID 315

Query: 69  NIGTFETRVE 40
            +G    R E
Sbjct: 316 GLGAQRIRCE 325


>UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep:
           Isomerase-like protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 224

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/181 (36%), Positives = 102/181 (56%), Gaps = 2/181 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ VGLNY  H +E     P+ P +F K  S+ +    TI++   +  ++  E+EL VV
Sbjct: 15  KIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIPHPLD-SLHHEVELAVV 73

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 313
           IG+KA  V    A +Y+ GY +A D+ A + + +   S L   L K  DTF PI   ++ 
Sbjct: 74  IGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLAKGQDTFTPISS-VLP 132

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
              + +P NL +   ++   +QK  T   I K+P +I+ +S+VMTL  GD+ILTGTP G+
Sbjct: 133 KAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFKGDVILTGTPEGI 192

Query: 132 G 130
           G
Sbjct: 193 G 193


>UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Bacillus coagulans 36D1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Bacillus coagulans 36D1
          Length = 278

 Score =  111 bits (267), Expect = 2e-23
 Identities = 79/219 (36%), Positives = 99/219 (45%), Gaps = 6/219 (2%)
 Frame = -3

Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELP------FIFNKFPSTVVGPNDTIKLKMDVSK 520
           V G  K+    +NY  H EE        P       +F K P ++ GP D I L     +
Sbjct: 72  VPGAGKIWAAPVNYLKHQEEMNHQFNNAPRTIEELSLFLKSPQSLSGPTDPIILPFP-ER 130

Query: 519 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 340
               E EL  ++GKKA  V +  A DY+ GY    DI     E+          K+ DTF
Sbjct: 131 RTDHEAELGYIVGKKAKNVKAREAKDYIFGYFALLDISIRGNEERT------WRKSFDTF 184

Query: 339 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 160
            PIGPWIVT DEI NP +L +   +N   +Q  +T   I+          + MTL PGDI
Sbjct: 185 TPIGPWIVTEDEIKNPNDLAISLWVNDELRQSGSTKYLIYDCYKCFELACDHMTLHPGDI 244

Query: 159 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           I TGTP GVG  R        GD +   IE IG F   V
Sbjct: 245 IATGTPEGVGPIRE-------GDRVKISIEQIGEFTVDV 276


>UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 296

 Score =  111 bits (266), Expect = 2e-23
 Identities = 65/208 (31%), Positives = 108/208 (51%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++CV LNY    +E     P  P  F K P T +  +    ++ +  K +  E E+ +V
Sbjct: 47  KIICVHLNYHSRVQEFITKLPPAPTYFQK-PLTALNTHKGAIVRPERCKWLNYEGEIAIV 105

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IGK    +  + A DY+LGY++A D G  D+ ++     +L  K  DT CPIGP +VT  
Sbjct: 106 IGKTCRNISPAEAGDYILGYSVANDYGLHDF-RDTDAGSMLRVKGSDTLCPIGPGLVTGW 164

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
           +  +     ++  +NGV KQ+ NT+     +  ++A ++  +TL PGD++L+GTP     
Sbjct: 165 DFRDKM---IRTYVNGVLKQEDNTSNMEWDMHYLVADIARTITLEPGDVLLSGTPAN--- 218

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
              P   +Q GDV+  E++ +G     +
Sbjct: 219 -SRP---VQIGDVVEVEVDGLGRLSNTI 242


>UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 255

 Score =  111 bits (266), Expect = 2e-23
 Identities = 80/208 (38%), Positives = 106/208 (50%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+ +G NY D        P   P IF K  ++VVGP+D I +    S AV  E EL +V
Sbjct: 59  KVVGIGDNYSDTPIPADERPE--PPIFLKANTSVVGPDDPIAIPA-WSNAVAFEGELAIV 115

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           I   A  V    A   +LGYTIA D  A D       S+   GK+ D+ CP+GPWI T D
Sbjct: 116 IKSLAKDVSVEDAPQMILGYTIANDATARDAMTGGPWSR---GKSFDSACPLGPWI-TVD 171

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
              +  NL ++  +NG   Q S+T   I    ++++ LS+ MTLLPGD+I TG P G   
Sbjct: 172 PALDVTNLAIRSYLNGEIAQDSSTAHMIWNPFELVSYLSHQMTLLPGDVIATGAPAGA-- 229

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43
                E +  GD +  EIE IG+    V
Sbjct: 230 -----EIVHAGDRVEIEIEGIGSLTNPV 252


>UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=11;
           Bradyrhizobiaceae|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rhodopseudomonas palustris
          Length = 233

 Score =  110 bits (265), Expect = 3e-23
 Identities = 68/210 (32%), Positives = 101/210 (48%), Gaps = 2/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           ++ CVG NY +H  E      + PF F K    V     TI     ++K +  E+EL V 
Sbjct: 29  RIWCVGRNYLEHVREMGNDERQPPFFFAKHADMVTPDGATIPYP-PLTKDLHHEVELVVA 87

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIVT 313
           +      +    A D+V GY +  D+   D +    KK     +GK+ D   P G  +  
Sbjct: 88  LKSGRLNIPVERALDHVWGYAVGIDLTRRDLQIASRKKEQPWEIGKSFDASAPCGA-LRP 146

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           + EIG+P    +  S+NG ++Q  + ++ I  +P+IIA+LS  + L  GDII+TGTP GV
Sbjct: 147 ASEIGHPATGKIWLSVNGTERQTGDLSEMIWNVPEIIAKLSAQVELAAGDIIMTGTPAGV 206

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
                    L PGD I   I+ IGT    +
Sbjct: 207 AA-------LSPGDAIACGIDGIGTLNVTI 229


>UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Silicibacter pomeroyi|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Silicibacter pomeroyi
          Length = 281

 Score =  110 bits (265), Expect = 3e-23
 Identities = 62/211 (29%), Positives = 104/211 (49%), Gaps = 3/211 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFI--FNKFPSTVVGPNDTIKLKMDVS-KAVVCEIEL 496
           K+LC G+NY+       + PP+   +  F++ P T+VG    +++    + ++   E E+
Sbjct: 72  KILCAGMNYRKPYPVAGVAPPDPGHVVLFSRHPQTLVGHGAMLEMPQGAAAESFDFEGEI 131

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
             VIG+    +    A  +VLGY+   +     W K+     +  GK        GPWI 
Sbjct: 132 VAVIGQPGRHIAPEAALGHVLGYSAMNEGSVRGWMKHS----VHAGKNFHASGSWGPWIT 187

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           T+DE G+   + ++  +NG   Q  +    I  + ++IA +S++  L  GDII TG+P G
Sbjct: 188 TADEAGDIAGMTLETRVNGTPMQSDSGAGMIFGLAELIAYISHIQPLEAGDIIATGSPDG 247

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            G  R PP FL+ GD +   +  +GT +  V
Sbjct: 248 TGGSRTPPAFLRSGDRVAVTVGGVGTLKNTV 278


>UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 325

 Score =  110 bits (264), Expect = 4e-23
 Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 4/199 (2%)
 Frame = -3

Query: 627 EEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHA 448
           ++ K  PP  P++F K  +   G  D I L   + + +  E EL VVIG     +  + A
Sbjct: 121 DQGKQLPPLRPYMFGKI-NVPTGAFDDIILPPGMER-IDWEAELMVVIGTPGLAIRPAEA 178

Query: 447 FDYVLGYTIAQDIGATD--WEKNKKI--SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLN 280
             ++ GY    D+   D  W +++    S  L GK+ D+F P+GP +     + +  +L 
Sbjct: 179 HRHIAGYMTGNDVSCRDRTWREDRPTIRSDWLGGKSYDSFAPLGPLLTPRQFVPDHADLA 238

Query: 279 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQ 100
           ++  +NG  KQ  N+      I + I   S++MTLLPGD+I TGTP G G  R   EFL+
Sbjct: 239 IRLWVNGELKQDGNSRDMTFGIEEQIEYASSMMTLLPGDVIATGTPAGTGQERG--EFLK 296

Query: 99  PGDVITSEIENIGTFETRV 43
            GD++ +E+E+ G    RV
Sbjct: 297 EGDIVETEVESCGRQRNRV 315


>UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2;
           Eurotiomycetidae|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 327

 Score =  109 bits (262), Expect = 6e-23
 Identities = 65/210 (30%), Positives = 108/210 (51%), Gaps = 3/210 (1%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVV 487
           ++CVGLNY++H  E  L  P  P ++ K P  +  P+  I +     K+    E ELT+V
Sbjct: 119 IICVGLNYRNHANEASLPIPTCPPMWYKAPPALADPDSEIPVPPQAQKSFPDFEGELTIV 178

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +      + +S A  ++LGYTI  D+ A  +++     Q    K  D F P+GP +V   
Sbjct: 179 LRNTIKSISASEATSHILGYTIGNDLTARFFQRACG-GQYTHAKGFDNFAPLGPRLV-HP 236

Query: 306 EIGNPQNLN--VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
            + +P + +  +   +NG   Q S  + FI  + ++++ LS   T+  G  I+TGTP GV
Sbjct: 237 SVFSPSDASRRITTRVNGRVVQDSPFD-FIFPVDELVSFLSEGTTIPAGTAIMTGTPAGV 295

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           G +++P   LQ GD +  E++ IG     +
Sbjct: 296 GWFQDPKCPLQHGDAVEVEVQPIGVLRNTI 325


>UniRef50_Q8G4X7 Cluster: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the
           fumarylacetoacetate hydrolase family; n=6;
           Bifidobacterium|Rep: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the
           fumarylacetoacetate hydrolase family - Bifidobacterium
           longum
          Length = 292

 Score =  109 bits (261), Expect = 8e-23
 Identities = 69/184 (37%), Positives = 96/184 (52%), Gaps = 2/184 (1%)
 Frame = -3

Query: 606 PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGY 427
           PE   IF K  ++V+GP+D I      SK +  E E+ VV+G+ A  V   +A DYVLG+
Sbjct: 111 PEDMVIFTKPSTSVIGPDDPIVYPA-CSKDMNFEPEVAVVMGRIAKNVTVENAMDYVLGF 169

Query: 426 TIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSING--VQ 253
           T   D+   D +           K  DT CP+GPWIV  D++ + ++  +  ++NG  V 
Sbjct: 170 TCVNDVTLRDLQGIDPT--WTRAKGFDTSCPLGPWIVMRDDL-DWKDAKISFTLNGEDVP 226

Query: 252 KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 73
                T   IH IP+ IA +S+  TLLPGD+I+TGTP   G        L PGD     +
Sbjct: 227 MASGTTANLIHGIPEQIAAISSFSTLLPGDVIMTGTPNASG-------HLDPGDETIVHV 279

Query: 72  ENIG 61
           E IG
Sbjct: 280 EGIG 283


>UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase;
           n=123; Proteobacteria|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 252

 Score =  109 bits (261), Expect = 8e-23
 Identities = 69/208 (33%), Positives = 103/208 (49%), Gaps = 3/208 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +V CVG NY DH  E    P  E PF F K    +V  + T+     ++  +  EIEL V
Sbjct: 47  RVFCVGRNYADHAREMGADPDREPPFFFTKPADAIVPASGTVAYP-PLTNDLHHEIELVV 105

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAMDTFCPIGPWIV 316
            IGK    +D + A  +V GY +  D+   D +   KK+S+     K  D   P+   + 
Sbjct: 106 AIGKDGRAIDPADALSHVWGYGVGIDLTRRDLQAEAKKLSRPWDWAKGFDASGPVTA-LR 164

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
            +   G+P    +  ++NG  +Q+ +    I  +PD+IA +S  + L  GD+I TGTP G
Sbjct: 165 AASATGHPATGRIWLAVNGDTRQQGDLADMIWAVPDVIAYVSRSVELKAGDLIFTGTPAG 224

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFE 52
           VG        LQPGD +T  ++ + TFE
Sbjct: 225 VGA-------LQPGDRVTGGVDGVATFE 245


>UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Jannaschia sp. CCS1|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Jannaschia sp. (strain CCS1)
          Length = 271

 Score =  109 bits (261), Expect = 8e-23
 Identities = 70/215 (32%), Positives = 106/215 (49%), Gaps = 7/215 (3%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+LCV LNY DH +E     PE P +F K    ++     I+    +++ +  E EL ++
Sbjct: 59  KILCVALNYVDHAKEANQPVPETPIVFFKTFDAMIAGGAPIRAPRMITQ-LDYEGELALI 117

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK--ISQL--LLGKAMDTFCPIGPWI 319
           IGK+   +  + A+D++ G T   D+ A D  K K    S L    GK ++   PIGP +
Sbjct: 118 IGKRGFDIAKTDAWDHIAGVTTLNDVSARDIFKVKAGAASHLDWFSGKCLNQSTPIGPEV 177

Query: 318 VTSDEIGNPQNLN---VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
                I +        ++C +NG  +Q +     I  IP +IA +S+ + L PGDII TG
Sbjct: 178 FPLSAIEDDLKAGTTRIRCLVNGEVRQDAPVADMIFDIPTMIAFISSRIPLNPGDIIATG 237

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           TP GVG       +L  GDV+  E+  +   E  V
Sbjct: 238 TPPGVGA--GTDRYLSKGDVVRVEVTGLPPMENTV 270


>UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Comamonas testosteroni KF-1
          Length = 289

 Score =  109 bits (261), Expect = 8e-23
 Identities = 63/183 (34%), Positives = 96/183 (52%), Gaps = 5/183 (2%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG--PNDTIKLKMD-VSKAVVCEIEL 496
           ++ CVG NY+DH +E   T  E PF F K     V      T ++    +++ +  EIEL
Sbjct: 84  RIYCVGRNYEDHAKEMGFTGREPPFFFMKPADATVALEAGSTGQVAYPTLTQNLHHEIEL 143

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPW 322
            V IGK    + ++ A  Y+ GY +  D+   D   E  K+     +GKA +   PIGP 
Sbjct: 144 VVAIGKAGKNIKAADALQYIYGYAVGLDMTRRDLQNEMKKQGRPWCIGKAFEQSAPIGP- 202

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           I  +D+ G+  N  +   +NG  +Q+S+ ++ I  I + I  LS+   L PGD+I+TGTP
Sbjct: 203 ITPADQAGDIANAEISLQVNGDYRQRSHIHKLIWNIAETIEHLSSAWELQPGDLIMTGTP 262

Query: 141 GGV 133
            GV
Sbjct: 263 EGV 265


>UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella
           pertussis|Rep: Putative hydrolase - Bordetella pertussis
          Length = 316

 Score =  108 bits (259), Expect = 1e-22
 Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 5/192 (2%)
 Frame = -3

Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGY 427
           ++P  F K  S V+ P+D+   +     A   E+E+  V+G           A ++V GY
Sbjct: 126 DMPAGFIKIAS-VMTPHDSAVARPCGVLAFDYEVEVAAVLGGPVPLGTPPERALEHVFGY 184

Query: 426 TIAQDIGATDWEKNKKISQLL-LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
           T+  D+ A +W + +  +Q++ +GK      P+GPWIVT+DE+ +P  L +  S+NG  +
Sbjct: 185 TLFNDLSAREWARAEMKNQMIAMGKNFPGAGPLGPWIVTADEVPDPAQLELSLSVNGEPR 244

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP---PEFLQPGDVITS 79
           Q  +  + I     +IA  S +  L  G++I +GTP G  + R P   P FL+PGD++ +
Sbjct: 245 QHGSCKEMIFTFAQLIAHWSRI-GLGAGELIASGTPEGGAISRKPDPAPFFLKPGDIVEA 303

Query: 78  EIENIGTFETRV 43
               IGT  TR+
Sbjct: 304 HCPQIGTLRTRI 315


>UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=3; Burkholderiales|Rep: 2-Keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
           Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
           H16 / DSM 428 / Stanier337))
          Length = 301

 Score =  108 bits (259), Expect = 1e-22
 Identities = 60/163 (36%), Positives = 92/163 (56%), Gaps = 7/163 (4%)
 Frame = -3

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL------LG-KAM 349
           E EL VVIGK    +    A D V GYTIA D+ A D  + +++          +G K  
Sbjct: 141 EAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNLRREQVDASSPFRFDWIGHKCF 200

Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169
           +  CP+GP++  +  + +P+ L++K  +N   KQ SNT+  ++ + + IA LS  +TL P
Sbjct: 201 EGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSNHLYTVAEQIAYLSERLTLYP 260

Query: 168 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
           GD++LTGTP GVG+      FL+ GD I   I+ +G  ET ++
Sbjct: 261 GDVLLTGTPAGVGM--ESGVFLKRGDSIRVWIDGLGELETSLQ 301


>UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG10641.1 - Gibberella zeae PH-1
          Length = 230

 Score =  107 bits (258), Expect = 2e-22
 Identities = 62/151 (41%), Positives = 81/151 (53%), Gaps = 1/151 (0%)
 Frame = -3

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E EL VVIG+ A  V    A +YVLGYT A DI +   +  +  SQ    K  D  CP+G
Sbjct: 73  EAELAVVIGRAAKNVTKEEAMEYVLGYTAANDISSRTSQFGQ--SQWCFSKGFDGSCPLG 130

Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
           P +V+ D + +P   N++        Q    +  I  IP +I+ LS   TLLPG +ILTG
Sbjct: 131 PALVSKDLVPDPSMFNIRGLKKDQVLQDCGADDLIFDIPTLISFLSQGTTLLPGTVILTG 190

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEI-ENIGT 58
           TP GVGV R P   +  GD  + EI  +IGT
Sbjct: 191 TPAGVGVGRQPKVTISDGDEFSVEILPHIGT 221


>UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4;
           Alphaproteobacteria|Rep: Possible
           isomerase/decarboxylase - Rhodopseudomonas palustris
          Length = 329

 Score =  107 bits (257), Expect = 2e-22
 Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 2/187 (1%)
 Frame = -3

Query: 594 FIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQ 415
           +I N+F  +V G N  +K     S  +  E+E  ++  +K + + ++ A +++ GYTI  
Sbjct: 143 YITNRF--SVRGTNTVVKWPR-YSAVMDYELEFGIITKRKGANISAAQAKNHIFGYTIFN 199

Query: 414 DIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKS 241
           D  A D ++ +   +L    GK+ D    IGPWIVT DEIG+P  LN++  +NG  + + 
Sbjct: 200 DFSARDAQRIEMEGRLGPAKGKSFDGGNVIGPWIVTPDEIGDPYRLNMEARVNGEVRSRG 259

Query: 240 NTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 61
            T   +    +IIA +S   TL+PG+ I +GT G  G       FL+ GDVI  E+E IG
Sbjct: 260 VTEGMLFSFEEIIAHVSRDETLMPGEFIGSGTVGN-GCGLELGWFLEHGDVIELEVEKIG 318

Query: 60  TFETRVE 40
             + +VE
Sbjct: 319 IPKNKVE 325


>UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:
           ENSANGP00000019097 - Anopheles gambiae str. PEST
          Length = 232

 Score =  106 bits (255), Expect = 4e-22
 Identities = 64/188 (34%), Positives = 97/188 (51%), Gaps = 5/188 (2%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT---IKLKMDVSKAVVCEIEL 496
           K++  G+NYK+         P+ P IF K  S   G   T   I++       +  E EL
Sbjct: 24  KIIGAGVNYKEILRLTNSPKPDAPVIFFKPISGSTGSTGTPPTIRIPRVFGGVINFEAEL 83

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPW 322
            V+IG++ + V +  A  YV GY +A D+   D+  + +   L   LGK  DT  P+   
Sbjct: 84  GVIIGRRCANVPTDQAMAYVGGYCLALDMTGMDFILDARPKGLPWCLGKGFDTSTPVSAL 143

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           +  +D + NP ++ V C +NGV+KQ  +T   I  I ++IA +S  MTL   D++LTGTP
Sbjct: 144 VQRAD-LPNPDDVRVWCEVNGVRKQDDSTRNLIFPIAELIAYVSRFMTLEENDLLLTGTP 202

Query: 141 GGVGVYRN 118
            G G  R+
Sbjct: 203 AGAGPVRH 210


>UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Ralstonia pickettii|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Ralstonia pickettii 12J
          Length = 250

 Score =  106 bits (254), Expect = 6e-22
 Identities = 63/187 (33%), Positives = 96/187 (51%)
 Frame = -3

Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430
           PP+ P ++ K  +T +G    + L  DV   V     L V I   A++V + HA D++ G
Sbjct: 64  PPKAPILYLKPANTRIGHGHEVALPADVD-GVWAGACLGVAISCTATRVPAQHAADFIAG 122

Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
           YTI  D+        +     +  K  D FCP+GPW+V  D++ N   L++   ING  K
Sbjct: 123 YTIVNDLTVPHASYYRPA---IRHKCRDGFCPMGPWMVDRDDVPNADALDITVRINGEVK 179

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70
           Q++NT+  +  I  ++A ++  MTL  GD++L G P       NPP   + GD I  +I 
Sbjct: 180 QRANTSTLVRPIAQLLADVTAFMTLESGDVLLVGMP------ENPP-LARAGDRIDIDIA 232

Query: 69  NIGTFET 49
           +IGT  T
Sbjct: 233 HIGTLTT 239


>UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Thermosinus carboxydivorans Nor1|Rep:
           Fumarylacetoacetate (FAA) hydrolase - Thermosinus
           carboxydivorans Nor1
          Length = 295

 Score =  105 bits (252), Expect = 1e-21
 Identities = 65/181 (35%), Positives = 92/181 (50%), Gaps = 1/181 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPEL-PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           K+  +GLNY DH  +     P L P  F KF +T++GP + IK+ +  S+    E EL +
Sbjct: 88  KIWGIGLNYVDHAGDLAEKAPTLAPASFAKFDTTIIGPGEEIKIPLQ-SEKTTGESELAI 146

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           + GKK   V+     + V G+T   D+ A D  +      L   K  DTF   GP +VT 
Sbjct: 147 IFGKKCKDVEEKDWLNVVAGFTTIIDMTAEDILRINP-RYLTRAKNFDTFLSFGPVLVTP 205

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
           DEI +   LNV   ING    ++  +        +++  S V T+LPGDIILTGTP  V 
Sbjct: 206 DEIEDVNKLNVATVINGRIHARNVVSNMTFPPAYLVSFHSKVATMLPGDIILTGTPRAVQ 265

Query: 129 V 127
           +
Sbjct: 266 I 266


>UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Mycobacterium sp. JLS|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Mycobacterium sp. (strain JLS)
          Length = 265

 Score =  104 bits (250), Expect = 2e-21
 Identities = 69/213 (32%), Positives = 105/213 (49%), Gaps = 4/213 (1%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           V+ VG+NY  H E+  +T  P+    F K  + ++G  D +   + +++ +  E+EL VV
Sbjct: 54  VVGVGMNYWSHLEKLGVTERPKSTLGFLKPRAAIIGHGDVLANPV-ITEQLDFEVELVVV 112

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG-KAMDTFCPIGPWIVTS 310
           + +  S        + VLGYT+  D+ A D          L   KA+    P+GPWI T 
Sbjct: 113 LAQSVSH-PGGRPTEAVLGYTVGNDVSARDAAVPMSGGLDLFSIKALGGTTPVGPWITTK 171

Query: 309 DEIGNPQNLNVKCS--INGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           DE G    ++V  S  +NG Q+Q   T + I  I + +  +   M L  GDI+ TGT  G
Sbjct: 172 DEFGGSGQIDVGISLRVNGEQRQHDRTGKMIFSIDECLDYVVARMPLAAGDIVFTGTTHG 231

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37
           VG       +LQ GDV+ +E+E +G     V E
Sbjct: 232 VGF--EDGRYLQAGDVVEAEVEGVGVLRNIVGE 262


>UniRef50_Q3INL8 Cluster: Probable
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2;
           probable 5- oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase 2; n=1; Natronomonas pharaonis DSM
           2160|Rep: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase 2; probable 5-
           oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2 -
           Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 319

 Score =  104 bits (249), Expect = 2e-21
 Identities = 58/188 (30%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
 Frame = -3

Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424
           E+P  +     +VV P +T++     S  +  E+EL  VIGK+   + +  A +Y+ GYT
Sbjct: 135 EMPVYYKSTADSVVAPGETVEWPA-YSSLMDYELELAAVIGKEGRDIPAEAADEYIAGYT 193

Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 244
           I  D  A D +  +  ++L   K  D     GP++VT+D+  +P+   ++ ++NG    +
Sbjct: 194 IFNDFSARDIQGEEMQARLGPAKGKDFANAFGPYLVTADDF-DPETAEMRATVNGEVWSE 252

Query: 243 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVITSEIEN 67
               +  H   DI+A +S   TL PGD++ +GT G G G+     +FL+ GD ++  ++ 
Sbjct: 253 GTPGEMYHTFADIVAHVSQSETLYPGDVLGSGTVGEGCGLELG--QFLESGDTVSLFVDG 310

Query: 66  IGTFETRV 43
           IGT E  V
Sbjct: 311 IGTLENTV 318


>UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 295

 Score =  103 bits (248), Expect = 3e-21
 Identities = 65/211 (30%), Positives = 104/211 (49%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ V L Y+   EE     P  P  F K P+ + G    ++     ++ +  E EL V+
Sbjct: 57  KIIAVHLTYRSRVEEYGARVPPEPSYFLKPPTALNGHRGVVRWPAG-TRFLNYEGELAVI 115

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           +G++   V    A   V GYT A D+G  D+    + S L + K  D F P+GP +V + 
Sbjct: 116 VGRRMKGVGMEEALSCVAGYTCANDVGLHDFRHADRGSMLRV-KGQDGFLPLGPEVVPAS 174

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
              +P++  ++  +NG   Q+      +  +   +A L  ++TL PGD++LTGTP     
Sbjct: 175 RF-DPEDFALRTYLNGEVVQEGGAEDLLFGVAYQLADLCRLITLEPGDVVLTGTPAN--- 230

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34
              P   ++PGDV+  EIE IG     VEE+
Sbjct: 231 -SRP---MRPGDVVEVEIEGIGRLSNTVEEW 257


>UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Arthrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Arthrobacter sp. (strain FB24)
          Length = 277

 Score =  103 bits (248), Expect = 3e-21
 Identities = 65/187 (34%), Positives = 101/187 (54%)
 Frame = -3

Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418
           P  F+K  ++VVGP D I+L   V   V  E ELT+VIG+KA  +   +A   VLG+TI 
Sbjct: 102 PQAFHKAATSVVGPGDAIELAPGVGH-VDPEAELTIVIGRKARGLTLENARGAVLGFTIG 160

Query: 417 QDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSN 238
            D+ A + +K+ ++   +  K+ DTF P GPWIVT  +      L++    NG + + ++
Sbjct: 161 NDVTARELQKSDEL--WISAKSQDTFTPAGPWIVTGLDTA---ALSIGIVHNGSELRAAS 215

Query: 237 TNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 58
           +     K+ +I+  L++ MTL PGD++LTG P            L PGD +T  ++ IG 
Sbjct: 216 SADLGWKVDEILVYLTSFMTLHPGDLVLTGFPA-------ESARLHPGDTVTCRVQGIGE 268

Query: 57  FETRVEE 37
               V +
Sbjct: 269 LTNPVSD 275


>UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Aeropyrum pernix|Rep: Fumarylacetoacetate
           hydrolase family protein - Aeropyrum pernix
          Length = 286

 Score =  103 bits (248), Expect = 3e-21
 Identities = 64/204 (31%), Positives = 106/204 (51%)
 Frame = -3

Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475
           VG +Y +H  E  ++  ++ F F+K  +++ G  + + +   VS+    E E+ ++IGK+
Sbjct: 82  VGRSYAEHAREMGMSK-QIAF-FSKPVTSLTGHLNPVVVP-PVSEKPDYEGEIVIIIGKR 138

Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 295
                ++ A   + GYT   DI  TD      +S  +  K +DT+ P+GP     D   +
Sbjct: 139 IKNASTAEAGKAIAGYTAGADI--TDRLLQDMMSWSM-AKGLDTYGPVGPVATIIDSPDD 195

Query: 294 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115
              L V   +NG + Q+  T   I  IPD+++RLS + TL PGDI+ TGTP GVG  R P
Sbjct: 196 LDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGTPPGVGHARKP 255

Query: 114 PEFLQPGDVITSEIENIGTFETRV 43
           P +L+ GD +   +  +     ++
Sbjct: 256 PRYLRHGDELEVRVSGLPPLRNQI 279


>UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium
           japonicum|Rep: Blr7583 protein - Bradyrhizobium
           japonicum
          Length = 261

 Score =  103 bits (246), Expect = 5e-21
 Identities = 66/210 (31%), Positives = 98/210 (46%), Gaps = 6/210 (2%)
 Frame = -3

Query: 657 CVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496
           CVGLNY  H +E      +    P+ P I  +  + ++  ++ + +    +  +  E EL
Sbjct: 58  CVGLNYLKHLKEAADKRGEVPAVPDRPEIGYRAQNALIAHDEEVVIPSFATDKIHYEGEL 117

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316
            VVIGKK   +   +A D V GYTI  D+    W+K  +   L   K  DTF P+GPWI 
Sbjct: 118 VVVIGKKVKHLTKQNAMDCVFGYTIGNDVSERSWQKADR--SLWRSKNADTFKPMGPWIE 175

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           T     N   +     +NG +  +  TN  I  +   +  L+   TL PGD+I  GT G 
Sbjct: 176 TE---ANLARMETVVRVNGKETNRFYTNDMIFGVVPFLVELTKYFTLWPGDVIWMGTDGA 232

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETR 46
                  P+ ++ GDV+  +I  IGT   R
Sbjct: 233 ------SPD-IKHGDVVEIDITGIGTLRNR 255


>UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=1;
           Schizosaccharomyces pombe|Rep: Uncharacterized hydrolase
           C21C3.09c - Schizosaccharomyces pombe (Fission yeast)
          Length = 221

 Score =  103 bits (246), Expect = 5e-21
 Identities = 67/202 (33%), Positives = 107/202 (52%), Gaps = 4/202 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKMDVSKAVVCEIELTV 490
           KV+C+G NY  H  E     P  PF F K  S +V P +  + +  DVS     E+ L +
Sbjct: 7   KVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELGLIM 66

Query: 489 VIGKKASKVDSSHAF-DYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 319
                A +  SS+++ D +  Y +  D+ A + +   K   L     K  DTF P+GP I
Sbjct: 67  KDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGP-I 125

Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
           +    I +P N+ ++ S+NG   QK +T+  ++KIP I + ++  M+L PGD++LTGTP 
Sbjct: 126 IPKHLIPDPHNVILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVLTGTPK 185

Query: 138 GVGVYRNPPEFLQPGDVITSEI 73
           GVG        + PGD++++ +
Sbjct: 186 GVGP-------VVPGDILSARL 200


>UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP02096p
           - Drosophila melanogaster (Fruit fly)
          Length = 236

 Score =  102 bits (245), Expect = 7e-21
 Identities = 71/211 (33%), Positives = 105/211 (49%), Gaps = 2/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++ V LNY D    + +  P+ P +F K  S+ +     I L    +K V  E+EL VV
Sbjct: 33  KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPIVLPKVFTK-VAYEVELGVV 91

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 313
           IGK    V  + A  YV GY +A D+ A       + +     LGK  DT  P+  +I  
Sbjct: 92  IGKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFIPI 151

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
            +++ +P NL +  ++NG  KQ   T   I K+PDII+ +S  MTL   D+ILTGTP G 
Sbjct: 152 -EKVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGA 210

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
             ++        GDVI   + ++     +VE
Sbjct: 211 DAFK-------AGDVIQCGMADLAKLTFQVE 234


>UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           fumarylacetoacetate hydrolase family protein -
           Tetrahymena thermophila SB210
          Length = 218

 Score =  101 bits (243), Expect = 1e-20
 Identities = 68/181 (37%), Positives = 92/181 (50%), Gaps = 4/181 (2%)
 Frame = -3

Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           N K+L +  NY      QK  P + P IF K  S+++   + + L       +  EIEL 
Sbjct: 13  NPKILALAQNYIP--PGQKDVPAQ-PLIFTKPHSSILYKGENLILNS--KNQINYEIELG 67

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ----LLLGKAMDTFCPIGP 325
           V+IGK    +    AFDY+ GY +  D+  TDW+  K   +      +GK  D F PI  
Sbjct: 68  VMIGKSGKNIAKQQAFDYIGGYFLCLDM--TDWDMQKANRKNGFPWDIGKGQDGFLPISD 125

Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
           +I   D I +P N+N+K  IN   +   NT     KI DII  +S  MTL PGD+ILTGT
Sbjct: 126 FIEKKD-IKDPHNINLKLQINQKSEVDDNTKNMYFKIDDIIQYVSQYMTLNPGDLILTGT 184

Query: 144 P 142
           P
Sbjct: 185 P 185


>UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep:
           MelH protein - Melittangium lichenicola
          Length = 329

 Score =  101 bits (243), Expect = 1e-20
 Identities = 63/192 (32%), Positives = 100/192 (52%), Gaps = 7/192 (3%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           V+C G NY+ H  E    P    F   F K  S++   +  I +K +  + +  EIEL +
Sbjct: 74  VVCQGQNYRSHMLEVGQDPEAKNFNQFFRKASSSLTSGHGDI-VKPERVRMLDYEIELGL 132

Query: 489 VIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319
           VIG+  S   +V+     ++V G  I  D+ A D +  +   Q    K+  TFCP GP++
Sbjct: 133 VIGRPLSGPCRVERERLHEFVAGLVICNDVSARDIQLAE--GQWYKSKSFRTFCPAGPYL 190

Query: 318 VTSDEIGNPQNLNVKC--SINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
              D   N + +N+K   S+N   +Q SNT++ ++   + ++ LS VM L PGD+++TGT
Sbjct: 191 YLLDAEDNARVMNLKLHLSVNDQTRQDSNTSEMVYPPEETLSELSEVMDLFPGDLVMTGT 250

Query: 144 PGGVGVYRNPPE 109
           P GV    N P+
Sbjct: 251 PRGVAAGHNAPK 262


>UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=25; Enterobacteriaceae|Rep:
           Fumarylacetoacetate hydrolase family protein - Erwinia
           carotovora subsp. atroseptica (Pectobacterium
           atrosepticum)
          Length = 218

 Score =  101 bits (242), Expect = 2e-20
 Identities = 69/211 (32%), Positives = 103/211 (48%), Gaps = 2/211 (0%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +KV+CVG NY +H +E     P  P +F K  + +      + +  ++  +V  E+EL V
Sbjct: 17  NKVVCVGSNYSEHIKEMGSATPSEPVLFIKPETALCDLRQPVAIPKNLG-SVHHEVELAV 75

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAMDTFCPIGPWIV 316
           +IG    + +       + GY +A D+   D +   KK  Q     KA D  CPI  +I 
Sbjct: 76  LIGTPLKQANEERVARAIAGYGVALDLTLRDLQSEFKKAGQPWEKAKAFDGSCPISGFIP 135

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
            + E G+PQ   +   +N   +Q+ NT   I  I  +IA +S   TL  GDIILTGTP G
Sbjct: 136 VA-EFGDPQQTELGVKVNDEVRQQGNTRDMITSILPLIAYMSRFFTLRAGDIILTGTPKG 194

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           VG        +  GD++T  + N  T  TR+
Sbjct: 195 VGP-------ILSGDMLTITV-NDRTLSTRI 217


>UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=8;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Silicibacter sp. (strain TM1040)
          Length = 256

 Score =  101 bits (242), Expect = 2e-20
 Identities = 65/182 (35%), Positives = 93/182 (51%), Gaps = 3/182 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +V C+G NY  H  E    P  E PF F K P ++          M  S+ V  E EL V
Sbjct: 55  RVYCIGRNYAAHAVEMGHDPDREPPFFFQKTPDSLDASGRFPYPVM--SEDVHHEAELLV 112

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK-NKKISQLL-LGKAMDTFCPIGPWIV 316
            +GK    +    A D+V GY +A D+   D +   KK  +   +GK+ +   P+ P + 
Sbjct: 113 ALGKGGENISEDAALDHVWGYGLALDMTRRDLQGIAKKAGRPWEIGKSFEHAAPVAP-LT 171

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
            +  IG+P    +  ++NG  +Q+ + NQ I KIP++IA LS    L  GD+ILTGTP G
Sbjct: 172 PATTIGHPDAGVMTLTVNGTPRQQGDLNQMIWKIPEMIAHLSQYYRLAAGDVILTGTPAG 231

Query: 135 VG 130
           VG
Sbjct: 232 VG 233


>UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Caulobacter sp. K31|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Caulobacter sp. K31
          Length = 293

 Score =  101 bits (242), Expect = 2e-20
 Identities = 63/204 (30%), Positives = 98/204 (48%), Gaps = 1/204 (0%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           DK++ +G  Y  H  E K      P +F + P ++V  N  I  + + S  +  E EL V
Sbjct: 78  DKIIGLGKTYMKHVAEMKAESSSFPGMFLRVPDSLVAHNQPI-WRPEASDTLDYEGELMV 136

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIG+    +   +A  +V GY    D     +  N   S +  GK        GP IVT+
Sbjct: 137 VIGQGGRMISRENALKHVAGYACHNDGSVRAY--NYIPSAVTAGKNFLNTGGFGPEIVTA 194

Query: 309 DEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           DE+    + L +   +NG  +Q ++  +    +  ++  +S + TL PGD+I TGTP G 
Sbjct: 195 DELPPGCKGLRLTTHVNGDLRQSADVAELHWDVAHLVHLMSTIFTLYPGDLIATGTPSGC 254

Query: 132 GVYRNPPEFLQPGDVITSEIENIG 61
                 P++L PGDV+  EIE +G
Sbjct: 255 AAASANPQWLVPGDVVRVEIEGVG 278


>UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation;
           2-hydroxyhepta-2,4-diene-1,7- dioate isomerase; n=8;
           Pseudomonas|Rep: 4-hydroxyphenylacetate degradation;
           2-hydroxyhepta-2,4-diene-1,7- dioate isomerase -
           Pseudomonas entomophila (strain L48)
          Length = 224

 Score =  100 bits (240), Expect = 3e-20
 Identities = 59/184 (32%), Positives = 95/184 (51%), Gaps = 1/184 (0%)
 Frame = -3

Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430
           PP  P +F K P+T       +     V K +     L VV+G+ AS+V + +A ++V G
Sbjct: 39  PPVKPVLFIKTPNTRNSHGQAVTYPAAV-KRLQPGPALGVVMGRDASRVSAENALEHVAG 97

Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
           YTI  +    +   +      +  K  D FCP+GP +V + ++ NP  L ++  +NG  +
Sbjct: 98  YTIVNEFSLPE---DSYYRPAVKAKCRDGFCPLGPQLVPAAQVANPDALGIRLWVNGELR 154

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP-GGVGVYRNPPEFLQPGDVITSEI 73
           Q +NT   +  +  +IA +S  MTL  GD+++TGTP G + V         PGD +T EI
Sbjct: 155 QHNNTANCVRSVAQLIAEISEFMTLHAGDVLITGTPEGRIDVL--------PGDRVTVEI 206

Query: 72  ENIG 61
           + +G
Sbjct: 207 DGLG 210


>UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 313

 Score =  100 bits (240), Expect = 3e-20
 Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
 Frame = -3

Query: 606 PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGY 427
           P +P +F K  ST+ GP   I +   V++    E+EL VV+G+    V    A D +LGY
Sbjct: 108 PVIPILFYKPISTLSGPGRDIVIPPCVAEQADYEVELVVVLGRDIKDVSPVEAMDAILGY 167

Query: 426 TIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE---IGNPQNLNVKCSINGV 256
           T++ D+ A    +   + Q  LGK+ D + PIGP +V++     I N  N+++   +N  
Sbjct: 168 TLSNDVSAR--TRMFAVPQWGLGKSFDGWLPIGPCLVSASNPRGITNRDNIHLTTKLNNR 225

Query: 255 QKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVI 85
             Q  NT+  + K  + +A LS   TL  G +++ GTP G G  R P   L  GD +
Sbjct: 226 IMQDGNTSDMLWKTAETLAELSKGTTLEAGSLLIMGTPPGEGFKRQPKVCLNHGDTL 282


>UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 255

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 60/197 (30%), Positives = 99/197 (50%), Gaps = 3/197 (1%)
 Frame = -3

Query: 621 QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVVIGKKASKVDSSHAF 445
           QKLT P  P ++ K  +++  PN+ I +    ++++   E EL  V  ++   V  S A 
Sbjct: 57  QKLTIPSNPPLWTKPAASLAHPNEEIPINDFCARSLPDYEGELVFVTSEECKDVTESQAK 116

Query: 444 DYVLGYTIAQDIGATDWEKNKKIS-QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCS 268
           DY+LGYTI  D+    ++    +S Q    KA D F PI P +++     + +   +   
Sbjct: 117 DYILGYTIGNDLTCRMFQLPGNMSGQFFFAKAFDHFAPIDPVLISPKLFESVKRNGLTLK 176

Query: 267 INGVQKQKSNT-NQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGD 91
           +NG  +QK++  N  I     I++ +S   T+  G  ++TGT  GVG +R P  FLQ GD
Sbjct: 177 VNGEVRQKADLHNDMIFSPERILSHMSQGTTIPAGTAVMTGTCEGVGAFRKPKVFLQQGD 236

Query: 90  VITSEIENIGTFETRVE 40
           V+   +   GT    ++
Sbjct: 237 VVEVSMPLAGTLRNTIK 253


>UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rubrobacter xylanophilus (strain DSM 9941 /
           NBRC 16129)
          Length = 349

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
 Frame = -3

Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418
           P++F   P+ + GP D + L  +  +    E+E   VIG+    V    A D V GYTIA
Sbjct: 145 PYLFLGSPTALCGPYDDVVLPAEGDQHD-WELEFAAVIGRSGRHVPPERALDLVAGYTIA 203

Query: 417 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
            DI   D      +  +    L  K   TF P GP+IV  + +G+   L +   +NG   
Sbjct: 204 NDITTRDLVYRPDLKAIGTDWLRSKNAPTFLPTGPYIVPKEFVGDTSGLRITLRLNGETM 263

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70
           Q  + +  I  +  +++  S+ + L PGD+ILTG+P G G Y     FL  GDV+   + 
Sbjct: 264 QDESASDMIFDVARLVSYASSRVLLRPGDLILTGSPAGNGSYWG--RFLGEGDVMEGTVT 321

Query: 69  NIG 61
            +G
Sbjct: 322 GLG 324


>UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH -
           Pseudomonas abietaniphila
          Length = 336

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
 Frame = -3

Query: 585 NKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIG 406
           N+F   V+G +D   L    SKA+  E+E    IGKK   +   +A D+++G+TI  D+ 
Sbjct: 147 NRF--AVIGADDEF-LWPAFSKALDFELEFGCYIGKKGKDISRDNARDHIVGFTIFNDMS 203

Query: 405 ATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTN 232
           A D +  +    L     K  DT   +GP +VT+DE+G+P +LN+   +NG +  + NT 
Sbjct: 204 ARDAQAAEMPGMLGPAKSKDFDTANIMGPCLVTADELGDPYDLNMVARVNGEEWGRGNTR 263

Query: 231 QFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 64
               +  D+IA +S   TL PG+ + +GT G  G       +L+PGD +  E++ I
Sbjct: 264 DMRWRFEDVIAHISRSETLYPGEFLGSGTVGN-GCGLEQLRYLKPGDRVELEVDGI 318


>UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Jannaschia sp. (strain CCS1)
          Length = 305

 Score = 96.7 bits (230), Expect = 5e-19
 Identities = 59/191 (30%), Positives = 95/191 (49%), Gaps = 2/191 (1%)
 Frame = -3

Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424
           E P  +     + +G   T++     S  +  E+EL ++IGK+ + +    A +++ GYT
Sbjct: 115 EQPIYYKGNRMSFIGHGQTVRWPA-YSDYLDLELELAIIIGKEGADIPRETAHEHIWGYT 173

Query: 423 IAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
           I  D+ A D +  +   QL    GK  DT   +GPWIVT+DE+ +P  LN+  S+NG + 
Sbjct: 174 ILNDVSARDAQMREMAGQLGPAKGKDFDTGNILGPWIVTADEVSHPAVLNMDVSVNGERW 233

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70
               +         IIA +S    L PG++I +GT  G G      + L  GD++   IE
Sbjct: 234 GGGTSADMQFDFAQIIAHISASERLFPGEVIGSGTV-GTGCGLEIGKRLSDGDMMDLTIE 292

Query: 69  NIGTFETRVEE 37
            IGT    +++
Sbjct: 293 KIGTLTNTIKK 303


>UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep:
           Fumarylacetoacetate (FAA) hydrolase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 273

 Score = 95.9 bits (228), Expect = 8e-19
 Identities = 65/210 (30%), Positives = 106/210 (50%), Gaps = 2/210 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-SKAVVCEIELTV 490
           K+  +GLNY +H  +     P+ P  F K  S + GP+  I+L  +  S+ V  E EL V
Sbjct: 72  KLWGIGLNYAEHAGDLDEQRPDEPASFMKPSSVLTGPSGPIRLPPESQSERVTAEAELAV 131

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           V+G+    V+ +   D V G+    D+ A D  ++N +   L   K+ DTF   G  +  
Sbjct: 132 VMGRTCRNVEEAAFEDVVAGFLPVIDMTAEDVLQRNPRF--LTRSKSYDTFLVPGAALAV 189

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
            +E  +   L+V+  +NG  + ++     +    +I++  S+VMTL PGD+  TGTPG  
Sbjct: 190 PEEPLDLDALSVQTEVNGEIEAENEIRNMLFPPSEIVSFHSDVMTLEPGDLFSTGTPGAA 249

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43
                    ++PGD + + +E+IGT E  V
Sbjct: 250 --------HIEPGDEVRAVVESIGTVEAPV 271


>UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Burkholderia phytofirmans PsJN|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Burkholderia phytofirmans PsJN
          Length = 346

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 59/181 (32%), Positives = 91/181 (50%), Gaps = 2/181 (1%)
 Frame = -3

Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418
           P+ F +  S +  P+  I  +    + +  E+EL +VIG++   V    A ++V    I 
Sbjct: 151 PYFFQRPNSCIAPPDGEIHAESGTEE-LDWELELGIVIGRRGRHVAREDAPNFVAACLIL 209

Query: 417 QDIG--ATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 244
            D+   A  + ++   +  L GK M    P GP++V +  IG    L ++ S+NG   Q 
Sbjct: 210 NDVTDRALIYRQDFPGADWLRGKGMPASMPAGPYLVPASVIGEIDALRLRLSVNGEVMQD 269

Query: 243 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 64
                 I  +P +I  LS+ + L PGD+I TGTP G G  R    FLQ GDVI +EI+ +
Sbjct: 270 ELAGDMILDVPRLIEYLSSRVELRPGDVIATGTPAGTGAERG--RFLQDGDVIRAEIDGL 327

Query: 63  G 61
           G
Sbjct: 328 G 328


>UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Pedobacter sp. BAL39|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Pedobacter sp. BAL39
          Length = 332

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 63/212 (29%), Positives = 98/212 (46%), Gaps = 23/212 (10%)
 Frame = -3

Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424
           + P  +    + + GP + I+   D  + +  E+E+ +VIGKK   + ++ A DY+ GY 
Sbjct: 109 QYPIFYFTNHNAIQGPGE-IECMPDHFQKLDFELEVAIVIGKKGRNITAAEADDYIAGYM 167

Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI------------GNPQNLN 280
           I  D+ A   +  + +  L   K  D    IGPW+VT DE+            G   NL 
Sbjct: 168 IMNDMSARTLQMEEMLLNLGPAKGKDFSTVIGPWLVTPDELEVYKTAAKSGHTGISYNLE 227

Query: 279 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG--------GVGVY 124
           +KC +NG Q    N         +II R +    +LPGD+I +GT G        G G+ 
Sbjct: 228 MKCLVNGQQVSSGNMADMDWTFAEIIERCAYGADILPGDVIGSGTVGTGCFLELNGTGLL 287

Query: 123 RNP---PEFLQPGDVITSEIENIGTFETRVEE 37
             P   P++LQ GDV+  EI  +G     + +
Sbjct: 288 NEPDFKPQWLQDGDVVEMEITGLGHLSNTIRK 319


>UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:
           PlaH - Streptomyces sp. Tu6071
          Length = 294

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/213 (32%), Positives = 100/213 (46%), Gaps = 5/213 (2%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496
           K+ CV LNY           P  P    +  K PST+VG    +    +  + +  E EL
Sbjct: 61  KIACVALNYAPQGSPTGPGRPANPAACSVVLKPPSTLVGHGAVVGHPGEPWE-LRHEAEL 119

Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPW 322
            VVIG     V +  A + V GYT A D+ A      ++ S    +  K  DTF P+GPW
Sbjct: 120 AVVIGTACKGVPAERAAEVVAGYTCADDLTAYVRRAPEEPSGHPPVWAKHFDTFTPLGPW 179

Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           + T  +   P ++ + C +NG  +Q   T   +  + +I+A +S  M+LLPGD+ILTGTP
Sbjct: 180 LTTDLD---PADVPITCRVNGEVRQDGGTRGLLTPVHEIVAVVSRHMSLLPGDVILTGTP 236

Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
            G G        L  GD +   +  IGT    V
Sbjct: 237 TGSGP-------LSVGDRVEVSLAGIGTLSHTV 262


>UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Moritella sp. PE36|Rep:
           Fumarylacetoacetate hydrolase family protein - Moritella
           sp. PE36
          Length = 231

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 57/182 (31%), Positives = 93/182 (51%), Gaps = 2/182 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+C+G NY DH  E     PE   +F K  +++V  +  + L +D+ +    E+E+ ++
Sbjct: 30  KVVCIGRNYLDHIRELGNDVPEQALLFIKPSTSLVALDKPLPLPVDLGECHN-ELEVALL 88

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 313
           I    +K  S    + + G  +  D+   D + + K         KA D  CP+ P+I  
Sbjct: 89  IKSPITKGTSIVLSELIWGVGLGLDLTLRDLQSSLKGQGHPWERAKAFDNACPVTPFIPL 148

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           + E G+  NL+   S+N   +Q+  T   +  I  ++  ++   TLLPGDI+LTGTP GV
Sbjct: 149 A-EFGDVNNLDFTLSVNDQLRQQGCTANMMRSIESLLTEITACFTLLPGDIVLTGTPAGV 207

Query: 132 GV 127
           GV
Sbjct: 208 GV 209


>UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1;
           Vibrio splendidus 12B01|Rep: Putative uncharacterized
           protein - Vibrio splendidus 12B01
          Length = 274

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 66/209 (31%), Positives = 98/209 (46%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +KV  VG+N+  H       PP +   F K PS+++   + I++    ++ V  E EL V
Sbjct: 80  EKVFAVGMNFASHLASPADAPPPM---FLKLPSSLILTGEVIQVPPK-ARNVHFEGELVV 135

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           VIG++ S+     A   + G T+  DI    W+      Q L  KA D F P+G  IV  
Sbjct: 136 VIGRELSQASEEEAEQAIFGVTVGNDITERSWQGADL--QWLRAKASDGFGPVGNTIVRG 193

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
            +  N   + +   +NG   Q+ NT+  IHK   +++ LS   TL PGD+I  GTPG   
Sbjct: 194 IDYNN---IELTTRVNGKVVQQENTSFMIHKPRKVVSYLSYYFTLKPGDLIFMGTPGRTY 250

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
                   L   D ++  IE +GT    V
Sbjct: 251 A-------LSDKDQVSVTIEGVGTVVNEV 272


>UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Nocardioides sp. JS614|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 280

 Score = 93.1 bits (221), Expect = 6e-18
 Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 3/189 (1%)
 Frame = -3

Query: 600 LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTI 421
           LP  +   P TV+GP D I      ++ +  E+EL  VIG+    +   +A D+V GYTI
Sbjct: 91  LPAYYKGLPDTVIGPEDEIPWPA-YTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTI 149

Query: 420 AQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQ 247
             D+ A D +  +    +  GKA   D    +GP IVT+DE+ +P ++ ++  +NG +  
Sbjct: 150 WNDLSARDVQAGELPVGMGPGKAKDWDGSNVLGPCIVTADEV-DPHDIELEVRVNGERWG 208

Query: 246 KSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT-PGGVGVYRNPPEFLQPGDVITSEIE 70
            +NT    H    +I   S  + L PG+++ +GT  GG GV      +L P D +  E  
Sbjct: 209 GANTRDMHHTFESMIVYASQALMLRPGEVLGSGTATGGSGVELG--RWLAPADTVEMEAS 266

Query: 69  NIGTFETRV 43
            IG     V
Sbjct: 267 GIGVLRNVV 275


>UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;
           Saccharomycetales|Rep: Uncharacterized hydrolase YNL168C
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 259

 Score = 93.1 bits (221), Expect = 6e-18
 Identities = 76/231 (32%), Positives = 113/231 (48%), Gaps = 33/231 (14%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP------------NDTIK-LKMD- 529
           K++C+G NY  H +E   + P+ PF F K  S++V P            N T   L  D 
Sbjct: 11  KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70

Query: 528 -------VSKAVVC--EIELTVVIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDW--E 391
                  + + V    EIEL +++ K  S   K+     +D + G  +A D+ A +   E
Sbjct: 71  TNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDE 130

Query: 390 KNKKISQLLLGKAMDTFCPIGPWIVTSDEIG----NPQNL-NVKCSINGVQKQKSNTNQF 226
             KK     + K  DTF PI   IV+ ++      N Q++  VKCS+NG  +Q   TN  
Sbjct: 131 AKKKGLPWTISKGFDTFMPISA-IVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLM 189

Query: 225 IHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 73
           +H +  I+  +S +++L PGDIILTGTP GVG        L+PGD +  E+
Sbjct: 190 LHPLHKILQHISTMISLEPGDIILTGTPAGVGE-------LKPGDRVHCEL 233


>UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Marinomonas sp. MWYL1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Marinomonas sp. MWYL1
          Length = 235

 Score = 92.7 bits (220), Expect = 8e-18
 Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 7/215 (3%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVV--GPNDTIKLKMDVSKAVV-CEIE 499
           +V CVG NY +H +E    P  + PF F K  S VV  G +++  +   ++ +    E+E
Sbjct: 26  RVYCVGRNYAEHSKEMGDDPERDPPFFFAKDSSCVVPAGFSESTLITYPMATSQFEYEVE 85

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLGKAMDTFCPIGP 325
           L + IGK    +    + + +LGY +  D+   D +    KK     +GK+ D   PI P
Sbjct: 86  LVIAIGKGGRNLTLQQSREAILGYAVGLDMTRRDLQSQAKKKGRPWEVGKSFDESAPISP 145

Query: 324 WIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148
            ++ +D +  N     +   +NG  KQ S+       I ++I +LS V  L PGD+I+TG
Sbjct: 146 ILLKTDLLADNVSKAEIGLKVNGDLKQISHVTNLTWSIEEVICKLSEVFELRPGDLIMTG 205

Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           TP  VG        +  GD + + +E++G     V
Sbjct: 206 TPENVGA-------VVVGDEMQAWVEHLGEIRVSV 233


>UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase
           precursor; n=4; Proteobacteria|Rep: Fumarylacetoacetate
           (FAA) hydrolase precursor - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 245

 Score = 92.7 bits (220), Expect = 8e-18
 Identities = 63/212 (29%), Positives = 105/212 (49%), Gaps = 4/212 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC-EIELTV 490
           +V C+G NY+    + +  P E+P  F K  + VV  +    L    +    C EIEL V
Sbjct: 30  RVFCIGRNYR--WSQDEAMPQEMPAWFMKPANAVVHAHGV--LPYPPATGDFCHEIELVV 85

Query: 489 VIGKKASKVDSSHAFDY-VLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWI 319
            IG+    +  +    + + GY    D+   D ++  K +       KA D   P  P +
Sbjct: 86  AIGRGGRDIAPAQVEPHHIWGYAAGLDLTRRDLQQQAKRAGGPWEAAKAFDHSAPCTP-L 144

Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139
           V +   G+P+   V  ++NG+++Q+++ +  +  + +++A LS  +TL+PGD+I TGTP 
Sbjct: 145 VPAAACGHPRQGAVWLTVNGIERQRADVSGLLWPVAELVAMLSRSVTLMPGDLIYTGTPA 204

Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           GVG        LQPGDV+   +  +G F   V
Sbjct: 205 GVGP-------LQPGDVVQGGVAGVGQFSMTV 229


>UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|Rep:
           Bll3146 protein - Bradyrhizobium japonicum
          Length = 262

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 54/166 (32%), Positives = 81/166 (48%), Gaps = 1/166 (0%)
 Frame = -3

Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430
           PPE P    K  +++  P   I+           E EL +VIG+  ++V    A  ++ G
Sbjct: 81  PPE-PLYLLKATTSIAAPGAVIRRPSYYDGKTTYEGELGIVIGRTCARVSPGEADSFIFG 139

Query: 429 YTIAQDIGATD-WEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQ 253
           YT   DI A D    +    Q    K +D + P GP I T  +   P  L V+  +NG +
Sbjct: 140 YTCVNDITANDILTSDPTFPQWARAKGIDDYGPFGPVIATGLD---PAKLVVRTILNGAE 196

Query: 252 KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115
           +Q    +  I    ++++R+S+ MTLLPGD+I  GT  GVGV + P
Sbjct: 197 RQNYPISDMIFSAQELVSRISHDMTLLPGDLIAVGTSVGVGVMKEP 242


>UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rubrobacter xylanophilus (strain DSM 9941 /
           NBRC 16129)
          Length = 320

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 60/201 (29%), Positives = 96/201 (47%), Gaps = 12/201 (5%)
 Frame = -3

Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424
           E+P  +   P +V+GP D + +     +A+  E+E+  +IG+  S +    A  ++ GYT
Sbjct: 98  EIPTFYFGNPYSVIGPQDPVAVPPGC-EALDFELEVAAIIGRAGSNLAPEEARGHIAGYT 156

Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSING 259
           I  D  A D ++++    L   K  D    +GPWIVTSDE+         +L ++  +NG
Sbjct: 157 ILNDWSARDLQRHEMQIGLGPAKGKDFANTLGPWIVTSDELEPYRRDGRLHLEMEVFVNG 216

Query: 258 VQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG-------VGVYRNPPEFLQ 100
            +              +++A  S    + PGD++ +GT G          V R  P  L+
Sbjct: 217 EKLGDDTLANMAWSFEELVAYASRGTWVRPGDVLGSGTCGSGCLAELWGRVGRQEPPLLE 276

Query: 99  PGDVITSEIENIGTFETRVEE 37
           PGDV+   +E IGT E RV E
Sbjct: 277 PGDVVRMTVEGIGTIENRVVE 297


>UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Sphingomonas wittichii RW1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Sphingomonas wittichii RW1
          Length = 276

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 1/209 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K + +G+NY+   E   +  PE P ++ + P+ ++G  D I L  D    VVCE EL  V
Sbjct: 76  KYVGIGINYRATAEALGMAMPEEPVVYVRPPNCIIGDGDRIVLPADGD--VVCEGELAAV 133

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDI-GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310
           IG++   +       +V+GYT+  D+     + K+K      L K  D F P+GP I T 
Sbjct: 134 IGRRGRDIAEGDVAAHVIGYTLTNDLMDVARFHKDK--GNPSLAKGRDGFAPLGPCIATG 191

Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130
            ++   +   +   +NG + Q       +  +   ++ +S  MTL PGD++  G P    
Sbjct: 192 LDLATAE---LATFVNGARVQAGFARDMLFGVERCVSHISRFMTLEPGDVVALGCP---- 244

Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43
                P  + PGD I      IGT    V
Sbjct: 245 ---PTPARIAPGDRIEIGCAPIGTLANEV 270


>UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=4; Oligohymenophorea|Rep: Fumarylacetoacetate
           hydrolase family protein - Tetrahymena thermophila SB210
          Length = 233

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 69/189 (36%), Positives = 95/189 (50%), Gaps = 9/189 (4%)
 Frame = -3

Query: 669 DKVLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPN--DTIKLKMDVSKAVVCEIE 499
           +K+L +G NY  H +E   +  P+ P IF K P + V PN     K++      V  EIE
Sbjct: 14  NKILAIGKNYVKHVKEMGGSEVPKEPVIFQK-PHSSVLPNIQKGQKVQFFTKNEVHHEIE 72

Query: 498 LTVVIGKKAS----KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFC 337
           L  ++ K+AS    +    +  DYV GY +A D+   + +   K +     L K  D F 
Sbjct: 73  LGFMMSKEASHKSFQKSGENWQDYVGGYFLALDLTDRNLQAAAKKAGFPWDLSKGQDKFL 132

Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157
           PI  +I   +++ +P NL +   ING   QK NT     KI D I   S  MTL PGD+ 
Sbjct: 133 PISSFI-PKEKVQDPYNLTLHLRINGKTIQKDNTGIMHFKIKDQIEYASKFMTLYPGDLF 191

Query: 156 LTGTPGGVG 130
           LTGTP GVG
Sbjct: 192 LTGTPDGVG 200


>UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=13; Bacillus|Rep: Fumarylacetoacetate
           hydrolase family protein - Bacillus anthracis
          Length = 318

 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 6/195 (3%)
 Frame = -3

Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424
           ++P  +      V+GPND + +    S+ +  E+E+  VIGK+   +    A +Y+ GY 
Sbjct: 107 DIPVFYFTNHRAVIGPNDVV-IGPKKSEKIDYELEIACVIGKEGRNISREQAEEYIFGYC 165

Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSING 259
           I  D  A D +  +    L   K  D    +G  +VT +E+     G+   L +   +NG
Sbjct: 166 IMNDWSARDLQATEMKVGLGPAKGKDFATSLGAHLVTKEELDVYRNGDRYELEMTAHVNG 225

Query: 258 VQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVIT 82
               K N     +   ++I R S  +TL PGD+I +GT G G  +     E+LQ GDV+ 
Sbjct: 226 KLLSKGNFQDIYYTFAEMIERASEDVTLYPGDVIGSGTVGTGCILELGTEEWLQDGDVVE 285

Query: 81  SEIENIGTFETRVEE 37
             I  +GT    V++
Sbjct: 286 LTITGLGTLRNTVKK 300


>UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2;
           Geobacillus|Rep: Hypothetical conserved protein -
           Geobacillus kaustophilus
          Length = 260

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 55/189 (29%), Positives = 92/189 (48%)
 Frame = -3

Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430
           PPE P ++ K  +T+      + L   V K +     L +VIG+ A++V    A D+V G
Sbjct: 75  PPEGPVLYMKPANTINAHRRPVLLPRWV-KHLQAAPALGLVIGRTAARVRREQALDFVFG 133

Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
           YTI  D+     ++++   +    +A D F P+GPWIV  +E     +L  +  +NG   
Sbjct: 134 YTIVNDLSIPHEQRHRPAVK---EQARDGFAPVGPWIVPKEEASPLSSLTARVYVNGRLV 190

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70
           Q+++ ++F   +   +A ++  MTL PGD++    P            +  GDV+  EIE
Sbjct: 191 QRADPSRFRLPVEQWLAEVTEFMTLYPGDVLFFSWPADA-------PLVTAGDVVRIEIE 243

Query: 69  NIGTFETRV 43
            IG  E  +
Sbjct: 244 RIGVLENEI 252


>UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=15; Ascomycota|Rep: Fumarylacetoacetate
           hydrolase family protein - Aspergillus fumigatus
           (Sartorya fumigata)
          Length = 235

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 6/210 (2%)
 Frame = -3

Query: 648 LNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKLKMDVSKAVVCEIELTVVIGKKA 472
           LN     +E   T P+ PF F K PS+++ P +  + L   VS  +  E+EL +V+GK  
Sbjct: 20  LNKSQLQKELNNTKPKQPFFFLKPPSSILLPREGPVLLPKGVS--LHYEVELALVMGKTV 77

Query: 471 SKVDSSH---AFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
             +D +    A D +  Y +A D+   +   E  KK     + K  DTF PI   I  + 
Sbjct: 78  RDLDPNDEKGALDAIRSYLLAIDMTGRNVQDEAKKKGLPWSIAKGFDTFLPISEEIPKA- 136

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
            I +P N  ++ S+    +Q  +T   +++IP  +A +S VMTL  GD++LTGTP GVG 
Sbjct: 137 RIPDPHNAFLRLSVGSQLRQADSTGLMLYRIPRQLAEISRVMTLEKGDLVLTGTPKGVGE 196

Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37
            +         +V   EIE  G  E  V++
Sbjct: 197 VKAGDVMKASIEVDGKEIEE-GRIEVEVKD 225


>UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7;
           Proteobacteria|Rep: Faa-hydrolase family protein -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 265

 Score = 89.4 bits (212), Expect = 7e-17
 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 6/185 (3%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTV--VGPNDTIKLKMD-VSKAVVCEIE 499
           ++ C+G NY  H  E    P  E PF F K    +  V P   +      ++K    EIE
Sbjct: 59  RIYCIGRNYAAHAREMGSDPTREPPFFFQKPSDAIQYVAPGKVVDHPYPTLTKNYHYEIE 118

Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQLLLGKAMDTFCPIGP 325
           L   I K    +   +A  +V GY +  D+   D +    K+     +GK+ D   PIGP
Sbjct: 119 LVAAINKGGKNISVENALQHVFGYAVGLDMTRRDLQAAMKKEEKPWEIGKSFDMSAPIGP 178

Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145
               +  IGN     +   +NG  KQ ++  Q I  + + I+ LS    L+PGDII +GT
Sbjct: 179 LHPVAS-IGNFTEGKIWLKVNGQVKQSADLKQMIWSVAEQISNLSKAFELMPGDIIYSGT 237

Query: 144 PGGVG 130
           P  VG
Sbjct: 238 PENVG 242


>UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:
           Putative hydrolase - Neisseria meningitidis serogroup C
           / serotype 2a (strain ATCC 700532 /FAM18)
          Length = 218

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 57/181 (31%), Positives = 89/181 (49%), Gaps = 3/181 (1%)
 Frame = -3

Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484
           + C+G NY  H EE K   P  P +F K   +++    TI L  + S+ V  E EL +++
Sbjct: 16  IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLP-EFSRDVQFECELVLLV 74

Query: 483 GKKASKV-DSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 313
           GK +  + +       V GY +  D+ A D + + K   L  L  K       +  +   
Sbjct: 75  GKDSDGMGEGEDILGCVAGYGVGLDLTARDIQCHLKAQGLPWLKAKGFRHSACVSDF-AA 133

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
           +D IGNP+ +      NGV KQ+ +T   I+ I +I+ +L+    L  GD++ TGTP GV
Sbjct: 134 ADRIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTPSGV 193

Query: 132 G 130
           G
Sbjct: 194 G 194


>UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=8; Actinomycetales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Mycobacterium sp. (strain JLS)
          Length = 529

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 60/201 (29%), Positives = 102/201 (50%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+ V LNY+    ++   P   P  F K P+++      ++     ++ +  E E+ +V
Sbjct: 47  KVIAVHLNYRSRAAQRGRFPGH-PSYFLKPPTSLALSGRPVERPAG-TRLLAFEGEIALV 104

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++  +V   +++D V     A D+G  D     K S L   K  D F PIGP ++++ 
Sbjct: 105 IGRRTRRVSPENSWDCVQFVCAANDLGVYDLRTVDKGSNLR-SKGGDGFTPIGPQLLSAR 163

Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127
            I +P  L V+  +NG   Q  +T+  +     +IA LS ++TL  GD+ILTGTP G  V
Sbjct: 164 GI-DPARLRVRTWVNGRLAQDGDTSDLLFPFTQLIADLSQLITLEAGDVILTGTPAGSSV 222

Query: 126 YRNPPEFLQPGDVITSEIENI 64
                  + PGD +  +++++
Sbjct: 223 -------VAPGDTVEVQVDSV 236


>UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Alphaproteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 265

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 65/211 (30%), Positives = 94/211 (44%), Gaps = 3/211 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490
           +V CVG NY  H  E    P  E PF F K    +V     I      +  +  EIEL V
Sbjct: 62  RVFCVGRNYAGHAREMGGDPNREAPFYFTKPADALVPGGGDIPYPPGTAN-LHHEIELVV 120

Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIV 316
            + +   K     A   + GY +  D+   D +     K     LGKA +   PI P +V
Sbjct: 121 ALSRSVYKCTPDEASTAIFGYAVGLDMTRRDLQFAARDKGRPWCLGKAFEFSAPISP-LV 179

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
            +D      ++ ++  +NG  +Q  + N+ I  +P++IA LS    L  GD+I TGTP G
Sbjct: 180 RADAPKLAGSITLE--VNGQIRQSGDLNEMIWSVPEVIAHLSQYYHLGAGDLIFTGTPEG 237

Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           VG        +  GDV+   IE +G  E  +
Sbjct: 238 VGP-------VVAGDVLRGAIEGVGELEVHI 261


>UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Sphingomonas wittichii RW1
          Length = 350

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 57/189 (30%), Positives = 94/189 (49%), Gaps = 3/189 (1%)
 Frame = -3

Query: 600 LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGYT 424
           +PFI+     ++VG ND + L   +      E EL +V+   A + +D   A +++ GYT
Sbjct: 140 MPFIWLATHGSLVGANDDVPLPQ-IGANHDWEAELCLVLAGGAPRYMDPEEAHEHIAGYT 198

Query: 423 IAQDI--GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250
           I  D+  G      + K +   + K+   F P+GP++V      +  +L +K  +NG  K
Sbjct: 199 IVNDMHTGELFSRDDIKWNADWIAKSPPGFKPVGPYVVPRQFFPDIDDLVIKLWVNGELK 258

Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70
           Q    N  I      +A  S  + +LPGD+++TG+P G G + N  +FL PGD +  EI 
Sbjct: 259 QDWPVNDMIFSSEHYVAYASERLKILPGDLLMTGSPPGNGAFHN--QFLVPGDTMDIEIS 316

Query: 69  NIGTFETRV 43
            +G    R+
Sbjct: 317 YLGRQRNRL 325


>UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate
           isomerase; n=4; Halobacteriaceae|Rep:
           2-hydroxyhepta-24-diene-1,7-dioate isomerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 238

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 59/207 (28%), Positives = 93/207 (44%)
 Frame = -3

Query: 657 CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGK 478
           CVG NY    ++     PE P  F K P+ ++     I       +      EL  VIG+
Sbjct: 48  CVGRNYAATNDQMDYDRPEEPDFFIKPPTALLAHEQNIPYPPFTDELTYAG-ELAAVIGE 106

Query: 477 KASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIG 298
           +   +D +   D V GYTI  D+ A D +           KA D   P+GPWI T+ +  
Sbjct: 107 RCHDIDPADVSDAVRGYTILNDVDALDQQGRTA------RKAFDGSGPLGPWIETAVD-- 158

Query: 297 NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRN 118
            P ++++   IN  ++Q +NT++ +    +++A LS   T  PGD++  G+P   G    
Sbjct: 159 -PTDIDMYTDINDERRQSANTSEMLFGPHEVVAYLSKRFTFRPGDVVAFGSPANPGT--- 214

Query: 117 PPEFLQPGDVITSEIENIGTFETRVEE 37
               + P D I    + +GT    V E
Sbjct: 215 ----VAPDDTIEITYDGVGTLRNSVVE 237


>UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Plesiocystis pacifica SIR-1
          Length = 287

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 62/206 (30%), Positives = 97/206 (47%), Gaps = 2/206 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KVL +G NY  H +E     P  P  F K PS ++     + L    ++ +  E EL +V
Sbjct: 82  KVLAIGRNYAAHAKELGNEVPSSPLSFFKPPSCLLASGQPLSLPRGYAR-IDMEAELVLV 140

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307
           IG++A ++ ++ A+ +V  Y +  DI   D +++ K  Q    K  D F P+  +   S 
Sbjct: 141 IGRRARQIAAADAWAHVGAYLMGNDISCRDLQRSDK--QWTRAKGFDGFGPVSAFARLSP 198

Query: 306 --EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
             E+     L V+  +     Q   T+  I  +P ++  LS  MTL  GD+I TGTP GV
Sbjct: 199 AAELPPVDALRVRGLLGDELVQDGPTSAMIFDVPTLLEHLSACMTLEVGDLIFTGTPAGV 258

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTF 55
                    L+PG V   E++   +F
Sbjct: 259 SA-------LEPGMVTRVELDGPPSF 277


>UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Alcanivorax borkumensis SK2|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 233

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 62/204 (30%), Positives = 96/204 (47%), Gaps = 3/204 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           KV+CVG NY DH +E     P+ P +F K  + +   ++ + L  +    V  E+E+ V+
Sbjct: 31  KVVCVGRNYADHAKELGNETPDAPILFMKPATALTSLHEPLVLP-EGQGPVHHEVEMVVL 89

Query: 486 IGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLGKAMDTFCPIGPWIV 316
           IGK+  K     H    V  Y I  D+   + +    +K       KA D   P+  +I 
Sbjct: 90  IGKRIRKETRLDHVRFSVAAYGIGLDLTLREVQNQLKEKGHPWERAKAFDGAAPVSGFI- 148

Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
            +  I   Q+L V   +N   KQ  +T Q +    ++++ +S   TL PGD++ TGTP G
Sbjct: 149 DARGISVRQDLGVTLELNDAVKQHGHTGQMLFPTFELLSEISQTFTLEPGDVVFTGTPAG 208

Query: 135 VGVYRNPPEFLQPGDVITSEIENI 64
           VG        L  GD  T+ + NI
Sbjct: 209 VGP-------LNSGDKFTARLGNI 225


>UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Burkholderia phytofirmans PsJN
          Length = 257

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 48/179 (26%), Positives = 85/179 (47%)
 Frame = -3

Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493
           ND+     L    H    K  PP+ P ++ K  +T+ G    + +  D +  V     L 
Sbjct: 49  NDRAALAALGDAVHAAPYK-APPQAPVLYLKPRNTLAGHRARVGVPDD-ALGVEVGASLG 106

Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313
           +V+G+ A++V  + AFDY+ GYT+  D+        +   +    +A D FC +GP +V 
Sbjct: 107 IVVGRTATRVGVAQAFDYIAGYTLVADLSVPHASVYRPSVRF---RARDGFCVVGPVVVA 163

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           S  +  P NL ++  +       ++T   +  +  ++A +++ MTL  GD+I  G P G
Sbjct: 164 SHHVATPDNLAIRVQLGSRDAFTASTASSVRNVAQLVADVTDFMTLSAGDVITLGVPHG 222


>UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8;
           Xanthomonadaceae|Rep: Fumarylacetoacetate hydrolase -
           Xanthomonas oryzae pv. oryzae
          Length = 290

 Score = 85.8 bits (203), Expect = 9e-16
 Identities = 63/212 (29%), Positives = 98/212 (46%), Gaps = 11/212 (5%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPP-------ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508
           ++ CVG N+ DH  E   + P       +  F      + VVG  D I      +K +  
Sbjct: 79  RIYCVGRNFADHAREMGASAPASKAERGQPTFFMKPADAIVVGHGDQIPYPPG-TKELHH 137

Query: 507 EIELTVVIGKKA--SKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTF 340
           E+EL V +G  A   ++    A   + GY +  D+   D +   K   L   + K  D  
Sbjct: 138 EVELVVALGSDAPAGELPVEQAERLIYGYGVGLDLTRRDLQAAAKAKGLPWDIAKGFDHS 197

Query: 339 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 160
            PI   +V + E+G  + LN+   +NG  +Q+S  +Q I  +P+I+  LS +  L  GD+
Sbjct: 198 APISE-LVHAGEVGVLEALNLSLEVNGQVRQQSLLDQMIWNVPEILHALSKLYALRAGDL 256

Query: 159 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 64
           I  GTP GVG        L PGD  ++ +EN+
Sbjct: 257 IFMGTPAGVGP-------LLPGDQFSARLENV 281


>UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=16; Bacteroidetes|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Psychroflexus torquis ATCC 700755
          Length = 204

 Score = 85.8 bits (203), Expect = 9e-16
 Identities = 62/211 (29%), Positives = 97/211 (45%), Gaps = 2/211 (0%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K++C+G NY  H  E K   PE P +F K  S+V+  N+   +    +K V  E+E+ V 
Sbjct: 2   KLICIGRNYAKHISELKNEKPEHPVVFLKPDSSVLLKNNPFIIPA-FTKEVHHEVEILVK 60

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVT 313
           I K    + +  A  Y     +  D  A D +   K   L   KA   D    IG   + 
Sbjct: 61  INKVGKHIQTKFAHKYYDEIGLGIDFTARDIQNQLKEQGLPWEKAKGFDGAAVIGETWLP 120

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133
            D   +  N++ +   N    Q  +T++ + +I ++IA +S   TL  GD+I TGTP GV
Sbjct: 121 KDRFQDLNNIDFRLEKNKTAVQSGSTSEMLWRIDELIAHVSEYFTLKIGDVIFTGTPAGV 180

Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40
           G        ++ GD +   IE+   F  +V+
Sbjct: 181 G-------RVEEGDHLEGFIEDTSCFSIQVK 204


>UniRef50_A4EDA6 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Roseobacter sp. CCS2|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Roseobacter sp. CCS2
          Length = 257

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 60/171 (35%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
 Frame = -3

Query: 645 NYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK 466
           N+    E  KL  P+ P  F K  S++ GPN  + L  ++ + VV E EL +VIGK    
Sbjct: 61  NFHAAAERNKLDIPQHPLFFLKPLSSLAGPNAQVALPPNIGR-VVYEGELGIVIGKTCKN 119

Query: 465 VDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQ 289
           +    A   +LGYT   DI A D   ++    Q    K  D F  IGP I T     N +
Sbjct: 120 ISVDAAESAILGYTCVNDITALDILFEDPSFPQWTRAKGYDGFGVIGPVIQTDL---NWR 176

Query: 288 NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136
           +L VK  +N  ++Q    +  I     I+++LS  MTL PGD+I  GT  G
Sbjct: 177 DLTVKVMVNDRERQSYPASDMIMNPAQIVSQLSTDMTLEPGDVIACGTSIG 227


>UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Polaribacter dokdonensis MED152|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Polaribacter dokdonensis MED152
          Length = 203

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 56/177 (31%), Positives = 85/177 (48%), Gaps = 2/177 (1%)
 Frame = -3

Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487
           K+L +G NY    ++         FIF+K P + +  N  +     ++  ++ E+EL V 
Sbjct: 2   KILGIGSNYVTDLKDIPEKKKGKKFIFSK-PESSLAVNCDVPYPSSITNELIYEVELVVK 60

Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFCPIGPWIVT 313
           IGK+   +    A  Y+    I  D  A D   N + ++      K  D   PI  +   
Sbjct: 61  IGKEGKNITKEEANSYISEIAIGIDYTAKDILTNARETKHPWEFAKGFDGAAPISSFKPI 120

Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142
           +D   +  N++    ING +KQKSNT   I+   DII+ +S  MTL PGD+I TGTP
Sbjct: 121 TDY--DLANIDFDLKINGEEKQKSNTAYMINNFADIISFISEYMTLQPGDLIFTGTP 175


>UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Sphingomonas wittichii RW1
          Length = 317

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 54/157 (34%), Positives = 75/157 (47%), Gaps = 2/157 (1%)
 Frame = -3

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFCP 334
           E+E   ++GK    +  + A  ++ GYTI  D+ A D +      Q+    GK  D   P
Sbjct: 155 ELEWACIVGKGGRNISPAQARAHIFGYTIFNDLSARDVQLAVMAGQIGPGAGKDFDNSNP 214

Query: 333 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 154
           IGP IVT+D I +P  L +  S+NG Q  + +T    H   D +  LS    L  G+II 
Sbjct: 215 IGPCIVTADAIPDPYALAMTASVNGEQWSRGSTASMHHSFEDAVVMLSRDRQLHAGEIIA 274

Query: 153 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           +GT    G        L PGDV+   +E IGT  T V
Sbjct: 275 SGTV-LTGCGFELQRRLSPGDVVELYVEAIGTLTTTV 310


>UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Roseiflexus|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Roseiflexus sp. RS-1
          Length = 333

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 47/163 (28%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
 Frame = -3

Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328
           E+E+  VIG+    +    A DY+ GY +  D  A D ++ + I+     K+ D    IG
Sbjct: 169 ELEVACVIGRSGRDISPEEAGDYIAGYLLLNDWTARDVQREELIAGFAFSKSKDAATSIG 228

Query: 327 PWIVTSDEI------GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 166
           PW+ T DE+          NL +   +NGV++ + N     +    +IA  S   TL PG
Sbjct: 229 PWLATPDELQEYALDDGQFNLTLIARVNGVEQSRGNLRDLTYSFAQMIAIASEGCTLFPG 288

Query: 165 DIILTGTPGG--VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43
           D+I  G  GG  +        +L+P D++  E   +G    R+
Sbjct: 289 DMIACGAIGGSLLEATNGQGPWLEPDDLVELEAGGLGILRNRI 331


>UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate
           isomerase; n=2; Sulfolobus|Rep: 2-hydroxyhepta-2
           ,4-diene-1,7-dioate isomerase - Sulfolobus solfataricus
          Length = 288

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 68/226 (30%), Positives = 108/226 (47%), Gaps = 21/226 (9%)
 Frame = -3

Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475
           VG+N K+  +E   +P      F K P+  +     I    D   A+  E+E+ V+   K
Sbjct: 66  VGVNDKNEAKEMVKSPK----FFIKLPTVAIAHRQPIISPPD---AIRPEVEIGVITRFK 118

Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK------------ISQLLL------GKAM 349
              V  S    Y+LGYT+  DI      K               + +LL+       K  
Sbjct: 119 MKDVSRSDVKKYILGYTVFNDITYPPGLKEDSYYAMRRDPTDGNVKKLLMRGTHFRNKVR 178

Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169
           DTF PIGP+IVT +EIG+  +L ++   NG   Q   +++FI  I +I++ LS ++T+ P
Sbjct: 179 DTFAPIGPYIVTEEEIGDVNSLRMRSYYNGELVQDGYSSEFIFSIEEILSELSKIVTIPP 238

Query: 168 GDIILTGTPGGVGVYRNPPEF-LQP--GDVITSEIENIGTFETRVE 40
             +I TG+ G   V  +  EF L+P    ++ +E+E IG  E  ++
Sbjct: 239 FSVISTGSIGYTNV-SDASEFNLKPIESALMVAEVEKIGRLENPIK 283


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 751,574,244
Number of Sequences: 1657284
Number of extensions: 16732770
Number of successful extensions: 45688
Number of sequences better than 10.0: 341
Number of HSP's better than 10.0 without gapping: 43218
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45079
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 53305790091
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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