BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fmgV11e01r (683 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A... 307 1e-82 UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B... 224 2e-77 UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylace... 236 4e-61 UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p ... 232 5e-60 UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 pr... 228 8e-59 UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-co... 225 8e-58 UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 211 1e-53 UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; ... 209 5e-53 UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 205 9e-52 UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 204 1e-51 UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 204 2e-51 UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 204 2e-51 UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 200 2e-50 UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 191 2e-47 UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 188 1e-46 UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 188 1e-46 UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 186 6e-46 UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 186 6e-46 UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 183 4e-45 UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 182 1e-44 UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 181 2e-44 UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family pr... 180 3e-44 UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family pr... 177 2e-43 UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 177 2e-43 UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 176 4e-43 UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 175 1e-42 UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 175 1e-42 UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 174 2e-42 UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre... 174 2e-42 UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 173 3e-42 UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; S... 173 3e-42 UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family pr... 172 6e-42 UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 172 6e-42 UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 171 1e-41 UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 171 1e-41 UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Eu... 171 1e-41 UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family pr... 171 1e-41 UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 170 3e-41 UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase ... 169 5e-41 UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;... 168 1e-40 UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family pr... 168 1e-40 UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Re... 167 2e-40 UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 167 2e-40 UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 167 2e-40 UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctiona... 167 3e-40 UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 166 5e-40 UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; ... 165 9e-40 UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 165 9e-40 UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 165 1e-39 UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 164 2e-39 UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 164 2e-39 UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Th... 164 2e-39 UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 163 4e-39 UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 163 5e-39 UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaste... 162 6e-39 UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 162 8e-39 UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-D... 161 1e-38 UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp... 161 1e-38 UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; ... 161 1e-38 UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family pr... 161 1e-38 UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: B... 161 1e-38 UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;... 161 1e-38 UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase... 161 1e-38 UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiale... 160 3e-38 UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium di... 160 3e-38 UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus ter... 158 1e-37 UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; ... 157 2e-37 UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 157 2e-37 UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 157 3e-37 UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 156 5e-37 UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 156 5e-37 UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 155 7e-37 UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 155 9e-37 UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farci... 155 1e-36 UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 154 2e-36 UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 153 3e-36 UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; ... 153 4e-36 UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 152 7e-36 UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 152 9e-36 UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 151 1e-35 UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 151 2e-35 UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 151 2e-35 UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisom... 150 3e-35 UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep... 150 4e-35 UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 150 4e-35 UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7... 149 5e-35 UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 149 5e-35 UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; c... 148 1e-34 UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; ... 147 2e-34 UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lm... 147 3e-34 UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family pr... 146 3e-34 UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 146 4e-34 UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 146 6e-34 UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase... 146 6e-34 UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 145 1e-33 UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 145 1e-33 UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomy... 145 1e-33 UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 144 2e-33 UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 144 2e-33 UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 144 2e-33 UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; ... 144 2e-33 UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family pr... 143 3e-33 UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584... 143 4e-33 UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family pr... 143 4e-33 UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydr... 142 5e-33 UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;... 142 5e-33 UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 142 9e-33 UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 141 1e-32 UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 141 1e-32 UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 141 1e-32 UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom... 141 1e-32 UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 141 2e-32 UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 140 3e-32 UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; ... 140 4e-32 UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifu... 139 5e-32 UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family pr... 139 7e-32 UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 138 1e-31 UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 138 1e-31 UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 138 2e-31 UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 137 2e-31 UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 137 2e-31 UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 137 3e-31 UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;... 136 4e-31 UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; F... 136 5e-31 UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_030014... 135 8e-31 UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 134 1e-30 UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 134 2e-30 UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 134 3e-30 UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;... 134 3e-30 UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate i... 134 3e-30 UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 133 3e-30 UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 132 6e-30 UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 132 6e-30 UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family pr... 132 8e-30 UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 132 1e-29 UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 132 1e-29 UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;... 131 2e-29 UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family pr... 130 3e-29 UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family pr... 130 3e-29 UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - P... 130 4e-29 UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate iso... 130 4e-29 UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 129 5e-29 UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 129 5e-29 UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 128 1e-28 UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 128 1e-28 UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomy... 128 2e-28 UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 127 2e-28 UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family pr... 127 2e-28 UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albic... 127 2e-28 UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase... 127 2e-28 UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 126 7e-28 UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; ... 126 7e-28 UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; E... 126 7e-28 UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; E... 125 9e-28 UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomy... 125 1e-27 UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 124 2e-27 UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 124 2e-27 UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase... 124 2e-27 UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISO... 123 4e-27 UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; ... 123 5e-27 UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 123 5e-27 UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albic... 121 1e-26 UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifu... 121 2e-26 UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 120 2e-26 UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Asc... 120 4e-26 UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria... 119 8e-26 UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gam... 119 8e-26 UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d... 118 2e-25 UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid... 118 2e-25 UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 118 2e-25 UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 117 2e-25 UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - P... 117 3e-25 UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 115 1e-24 UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;... 115 1e-24 UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-co... 114 2e-24 UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 113 3e-24 UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 113 5e-24 UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; ... 112 7e-24 UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 112 9e-24 UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep... 111 1e-23 UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 111 2e-23 UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 111 2e-23 UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23 UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 110 3e-23 UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family pr... 110 3e-23 UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 110 4e-23 UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; ... 109 6e-23 UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d... 109 8e-23 UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 109 8e-23 UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 109 8e-23 UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 109 8e-23 UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella per... 108 1e-22 UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohept... 108 1e-22 UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; ... 107 2e-22 UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; ... 107 2e-22 UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:... 106 4e-22 UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 106 6e-22 UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 105 1e-21 UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 104 2e-21 UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 104 2e-21 UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 103 3e-21 UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 103 3e-21 UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family pr... 103 3e-21 UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium ja... 103 5e-21 UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=... 103 5e-21 UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP020... 102 7e-21 UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase fa... 101 1e-20 UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep... 101 1e-20 UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family pr... 101 2e-20 UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 101 2e-20 UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 101 2e-20 UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-h... 100 3e-20 UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; ... 100 3e-20 UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19 UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 98 2e-19 UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - P... 97 3e-19 UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 97 5e-19 UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 96 8e-19 UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 95 2e-18 UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family pr... 94 2e-18 UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:... 94 3e-18 UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family pr... 93 4e-18 UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; ... 93 4e-18 UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 93 6e-18 UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;... 93 6e-18 UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 93 8e-18 UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre... 93 8e-18 UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|R... 92 1e-17 UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 91 2e-17 UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 91 2e-17 UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family pr... 91 2e-17 UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family pr... 90 4e-17 UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Ge... 90 5e-17 UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family pr... 90 5e-17 UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Prot... 89 7e-17 UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:... 89 1e-16 UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 88 2e-16 UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 88 2e-16 UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 88 2e-16 UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom... 88 2e-16 UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 87 4e-16 UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family pr... 87 5e-16 UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 87 5e-16 UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xan... 86 9e-16 UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 86 9e-16 UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 85 1e-15 UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 85 1e-15 UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 85 2e-15 UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 85 2e-15 UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate is... 85 2e-15 UniRef50_Q2BPV1 Cluster: Putative uncharacterized protein; n=4; ... 85 2e-15 UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 85 2e-15 UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 84 4e-15 UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 84 4e-15 UniRef50_Q88M65 Cluster: Fumarylacetoacetate hydrolase family pr... 83 8e-15 UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 82 1e-14 UniRef50_Q15XL1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 81 2e-14 UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family pr... 81 3e-14 UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14; Proteo... 81 3e-14 UniRef50_A4SV99 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 81 3e-14 UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 80 6e-14 UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family pr... 72 1e-13 UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXY... 78 2e-13 UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3; Betaproteobact... 77 3e-13 UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 77 3e-13 UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1; ... 77 3e-13 UniRef50_A1UG87 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 77 3e-13 UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Re... 77 5e-13 UniRef50_Q97VT9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 76 7e-13 UniRef50_Q0LGD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 76 9e-13 UniRef50_Q7WPF0 Cluster: Putative fumarylacetoacetate hydrolase ... 73 5e-12 UniRef50_Q0S954 Cluster: Possible hydratase; n=3; Actinomycetale... 73 5e-12 UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase ... 73 9e-12 UniRef50_Q4AQ85 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 72 1e-11 UniRef50_Q2W964 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 72 2e-11 UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family pr... 71 2e-11 UniRef50_A3SNB2 Cluster: Fumarylacetoacetate hydrolase family pr... 71 2e-11 UniRef50_A4QX03 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_Q18X79 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 71 3e-11 UniRef50_Q02AF6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 69 1e-10 UniRef50_Q4D6U8 Cluster: Putative uncharacterized protein; n=2; ... 68 2e-10 UniRef50_Q7MXX3 Cluster: Fumarylacetoacetate hydrolase family pr... 67 3e-10 UniRef50_Q395G4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 67 3e-10 UniRef50_Q3WGU5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 67 3e-10 UniRef50_Q6F7V5 Cluster: Putative uncharacterized protein; n=2; ... 66 6e-10 UniRef50_Q0SB97 Cluster: Possible fumarylacetoacetate hydrolase ... 66 6e-10 UniRef50_Q4J6K3 Cluster: 4-hydroxyphenylacetate degradation bifu... 66 6e-10 UniRef50_Q3II31 Cluster: Putative fumarylacetoacetate hydrolase ... 66 8e-10 UniRef50_Q4J7I6 Cluster: Conserved protein; n=3; Thermoprotei|Re... 66 1e-09 UniRef50_Q0AN49 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 65 1e-09 UniRef50_Q6KZ97 Cluster: Fumarylacetoacetase; n=2; Thermoplasmat... 65 2e-09 UniRef50_Q6MNK0 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09 UniRef50_Q8D6F8 Cluster: 2-keto-4-pentenoate hydratase; n=22; Pr... 62 1e-08 UniRef50_A7K1Y8 Cluster: Fumarylacetoacetate hydrolase family pr... 62 1e-08 UniRef50_Q3E159 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 61 3e-08 UniRef50_Q9CKS8 Cluster: HpaG; n=1; Pasteurella multocida|Rep: H... 60 4e-08 UniRef50_Q60C48 Cluster: Fumarylacetoacetate hydrolase family pr... 60 4e-08 UniRef50_Q8KDK4 Cluster: Fumarylacetoacetate hydrolase family pr... 60 7e-08 UniRef50_Q7UMG2 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 60 7e-08 UniRef50_Q5KYI4 Cluster: Hypothetical conserved protein; n=3; Ba... 60 7e-08 UniRef50_A0VBW0 Cluster: 4-hydroxyphenylacetate degradation bifu... 60 7e-08 UniRef50_Q4FWM5 Cluster: Putative uncharacterized protein; n=3; ... 59 9e-08 UniRef50_Q5B6D4 Cluster: Putative uncharacterized protein; n=1; ... 59 9e-08 UniRef50_A7D1J1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 59 9e-08 UniRef50_A1TDQ7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 59 1e-07 UniRef50_A5EF32 Cluster: Putative Fumarylacetoacetate (FAA) hydr... 58 2e-07 UniRef50_Q44SK1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 57 3e-07 UniRef50_A5VED2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 57 5e-07 UniRef50_A3VRL8 Cluster: Putative isomerase-decarboxylase-like p... 54 3e-06 UniRef50_A0SP98 Cluster: Fumarylacetoacetate hydrolase family pr... 54 4e-06 UniRef50_A3IA41 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 53 7e-06 UniRef50_A7QL05 Cluster: Chromosome undetermined scaffold_116, w... 52 1e-05 UniRef50_A1SUQ4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 52 1e-05 UniRef50_Q9KDZ0 Cluster: BH1071 protein; n=2; Bacillus|Rep: BH10... 52 2e-05 UniRef50_Q5V2I1 Cluster: Fumarylacetoacetate hydrolase family pr... 50 4e-05 UniRef50_Q1GRD3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 50 5e-05 UniRef50_A6Q9W9 Cluster: Fumarylacetoacetate hydrolase; n=1; Sul... 50 5e-05 UniRef50_Q5DHL1 Cluster: SJCHGC00506 protein; n=2; Schistosoma j... 49 9e-05 UniRef50_A6C0W6 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 48 2e-04 UniRef50_A3VNC8 Cluster: Possible isomerase/decarboxylase; n=1; ... 48 2e-04 UniRef50_Q0HT13 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 48 3e-04 UniRef50_Q2UV71 Cluster: Predicted protein; n=1; Aspergillus ory... 46 7e-04 UniRef50_A2UC21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 42 0.014 UniRef50_A6Q508 Cluster: Fumarylacetoacetate hydrolase family pr... 41 0.024 UniRef50_A7Q3E6 Cluster: Chromosome chr13 scaffold_48, whole gen... 39 0.13 UniRef50_Q4RJI4 Cluster: Chromosome 3 SCAF15037, whole genome sh... 38 0.30 UniRef50_Q1IPR5 Cluster: Fe-S protein, radical SAM family; n=5; ... 36 0.92 UniRef50_Q10JF6 Cluster: Isomerase, putative; n=10; Magnoliophyt... 36 1.2 UniRef50_Q6FUW3 Cluster: Similarities with sp|P08640 Saccharomyc... 36 1.2 UniRef50_Q5B250 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2 UniRef50_Q4X003 Cluster: Alpha-L-arabinofuranosidase A; n=7; Pez... 36 1.2 UniRef50_Q600A8 Cluster: Glucose-6-phosphate isomerase; n=3; Myc... 35 2.1 UniRef50_UPI0000E82426 Cluster: PREDICTED: hypothetical protein;... 34 2.8 UniRef50_Q6YRJ1 Cluster: Putative uncharacterized protein; n=1; ... 34 3.7 UniRef50_Q0TRU3 Cluster: Putative permease; n=1; Clostridium per... 34 3.7 UniRef50_A3Y335 Cluster: Putative uncharacterized protein; n=3; ... 33 4.9 UniRef50_UPI000023CD17 Cluster: predicted protein; n=1; Gibberel... 33 6.5 UniRef50_Q0D850 Cluster: Os07g0184600 protein; n=3; Oryza sativa... 33 6.5 UniRef50_Q245B0 Cluster: Putative uncharacterized protein; n=1; ... 33 6.5 UniRef50_Q0UDT0 Cluster: Predicted protein; n=1; Phaeosphaeria n... 33 6.5 UniRef50_P00815 Cluster: Histidine biosynthesis trifunctional pr... 33 8.6 >UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A; n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase isoform A - Bombyx mori (Silk moth) Length = 330 Score = 307 bits (754), Expect = 1e-82 Identities = 129/216 (59%), Positives = 172/216 (79%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 +HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+ ++++ DV+K V E+ Sbjct: 115 IHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEV 174 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL VV+G++AS V A +V GYT+AQDI A DW+K K + Q LLGK+MDTFCP+GP Sbjct: 175 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPC 234 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 ++TSDE+G L V CS+NGV KQ S+T Q +H IP ++ R+S+VMTL+PGD+ILTGTP Sbjct: 235 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 294 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 34 GGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F Sbjct: 295 GGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 330 >UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B; n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase isoform B - Bombyx mori (Silk moth) Length = 360 Score = 224 bits (547), Expect(2) = 2e-77 Identities = 97/158 (61%), Positives = 125/158 (79%) Frame = -3 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E+EL VV+G++AS V A +V GYT+AQDI A DW+K K + Q LLGK+MDTFCP+G Sbjct: 203 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG 262 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 P ++TSDE+G L V CS+NGV KQ S+T Q +H IP ++ R+S+VMTL+PGD+ILTG Sbjct: 263 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 322 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 34 TPGGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F Sbjct: 323 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 360 Score = 88.6 bits (210), Expect(2) = 2e-77 Identities = 31/55 (56%), Positives = 47/55 (85%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517 +HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+ ++++ DV+K+ Sbjct: 115 IHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKS 169 >UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylacetoacetate hydrolase domain containing 2A isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to fumarylacetoacetate hydrolase domain containing 2A isoform 2 - Apis mellifera Length = 334 Score = 236 bits (577), Expect = 4e-61 Identities = 112/210 (53%), Positives = 146/210 (69%), Gaps = 1/210 (0%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 DK+ CVGLNY HC+EQ ++PPE P IF+KF S ++GP D I L +S V E EL + Sbjct: 125 DKLACVGLNYIGHCKEQGVSPPESPVIFSKFASNIIGPRDNIMLP-PISDKVDWEAELAI 183 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS-QLLLGKAMDTFCPIGPWIVT 313 VIGKK ++++ DY+ GYTIAQDI A DW+K+K+ Q LLGKAMDTFCP+GP +VT Sbjct: 184 VIGKKCKALNNNEGEDYIFGYTIAQDITARDWQKSKRNGGQFLLGKAMDTFCPLGPAVVT 243 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + I + NL VK +NG KQ NT++ I K +I+A +S MTLLPGD+ILTGTP GV Sbjct: 244 KEAISDINNLTVKTWVNGNIKQDGNTSELIFKPHEIVAYISQFMTLLPGDVILTGTPSGV 303 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G R PPE+LQ GDV+ +EI+ +G +V Sbjct: 304 GFTRKPPEYLQRGDVLETEIQGLGRLRNKV 333 >UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p - Drosophila melanogaster (Fruit fly) Length = 293 Score = 232 bits (568), Expect = 5e-60 Identities = 105/202 (51%), Positives = 140/202 (69%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+GLNY+DHC+EQ P+ P F+KF + +VGP D + + S + E+EL V Sbjct: 84 KIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNV-IAHAASSKIDWEVELVCV 142 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK A +V S A DYV GY++AQDI A DW+K + Q L+GK+MDTF P+GP +V Sbjct: 143 IGKVARQVPKSQAMDYVFGYSVAQDISARDWQKERNGGQFLMGKSMDTFLPLGPAVVHKS 202 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + + NLN+K +NGV+KQ NT I K+ D+I RLS +TLLPGDII+TGTP GVG+ Sbjct: 203 LVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLPGDIIVTGTPKGVGM 262 Query: 126 YRNPPEFLQPGDVITSEIENIG 61 +R PPEFLQPGDV+ SEI +G Sbjct: 263 HRTPPEFLQPGDVVQSEIVGLG 284 >UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 protein; n=2; Gallus gallus|Rep: PREDICTED: similar to CGI-105 protein - Gallus gallus Length = 406 Score = 228 bits (558), Expect = 8e-59 Identities = 102/209 (48%), Positives = 142/209 (67%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +KV+CVGLNY+DHC EQ + P+ P IF+KFPS + GP D I + S+ V E+EL Sbjct: 198 EKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAESSE-VDWEVELAA 256 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 +IGK + S A ++++G+T+A D+ A DW+ + Q LLGK DTFCPIGP IVT Sbjct: 257 IIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFDTFCPIGPAIVTK 316 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 D + + NL ++CS+NG Q S+TNQ I ++P ++A +S +TL PGD++LTGTP GVG Sbjct: 317 DSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTLRPGDVLLTGTPPGVG 376 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 V+R PP FL+PGD + EIE +GT +V Sbjct: 377 VFRKPPMFLKPGDEVQCEIEELGTICNKV 405 >UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-containing protein 2B; n=41; cellular organisms|Rep: Fumarylacetoacetate hydrolase domain-containing protein 2B - Homo sapiens (Human) Length = 314 Score = 225 bits (550), Expect = 8e-58 Identities = 103/209 (49%), Positives = 138/209 (66%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 DKV+CVG+NY DHC+EQ + P+ P IF+KF S++VGP D + L S+ V E+EL V Sbjct: 106 DKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQ-SQEVDWEVELAV 164 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGKK + ++ A +V G+T+A D+ A DW + Q LLGK DTFCP+GP +VT Sbjct: 165 VIGKKGKHIKATDAMAHVAGFTVAHDVSARDWLTRRNGKQWLLGKTFDTFCPLGPALVTK 224 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 D + +P NL + C +NG Q SNTNQ + K D+IA +S +T PGD+ILTGTP GVG Sbjct: 225 DSVADPHNLKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPPGVG 284 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 V+R PP FL+ GD + EIE +G +V Sbjct: 285 VFRKPPVFLKKGDEVQCEIEELGVIINKV 313 >UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=3; cellular organisms|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus halodurans Length = 319 Score = 211 bits (515), Expect = 1e-53 Identities = 100/209 (47%), Positives = 134/209 (64%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVG NY++H E K P+ P IF KF +T++GP D + L +++ + E EL V Sbjct: 103 KIICVGHNYREHILEMKREIPKYPVIFAKFANTIIGPEDNVPLP-SITEQLDYEAELAFV 161 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGKKA V A DYV GYTI DI A D ++ + Q L GK +D P+GPW+VT D Sbjct: 162 IGKKAKDVAKEDALDYVAGYTIVNDITARDLQR--RTIQWLQGKTLDGSLPMGPWLVTKD 219 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI NP L + S+NG ++Q+SNT + I D++ LS +MTL PGD++ TGTPGGVGV Sbjct: 220 EIPNPHQLEITLSVNGEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCTGTPGGVGV 279 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 R P FLQ GDV+ E+E +GT E RV+ Sbjct: 280 AREPQLFLQDGDVVRIELEKVGTLENRVK 308 >UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 305 Score = 209 bits (510), Expect = 5e-53 Identities = 104/218 (47%), Positives = 137/218 (62%), Gaps = 9/218 (4%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+GLNYK+H E K+ P+ P +F+KF + + GPND+I +K S V E+EL VV Sbjct: 89 KIICIGLNYKEHANEAKMAIPKEPIVFSKFDNAICGPNDSI-IKPVESDEVDYEVELVVV 147 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK+A V S A YV GYT+ D+ A DW+ K SQ LLGK DTF PIGP IV + Sbjct: 148 IGKQAKNVSESDALQYVAGYTVGNDVSARDWQLRKNNSQWLLGKTFDTFAPIGPSIVINP 207 Query: 306 EIG--------NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151 E+ +P NL++KC++NG Q S T +FI I +++ LS + TL PGDII T Sbjct: 208 EVAALSDDTYFDPNNLSIKCTLNGQVVQNSTTKEFIFNIQTVVSYLSKLFTLNPGDIIFT 267 Query: 150 GTPGGVGVYRNP-PEFLQPGDVITSEIENIGTFETRVE 40 GTP GVG R P P FL+ GDVI EIE +G+ V+ Sbjct: 268 GTPSGVGFIRKPNPIFLKSGDVIKCEIEELGSLVNNVK 305 >UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Pirellula sp.|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Rhodopirellula baltica Length = 342 Score = 205 bits (500), Expect = 9e-52 Identities = 100/206 (48%), Positives = 128/206 (62%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K+LC+GLNY DH E P LP +F+KF S +VG I L +S V E EL V Sbjct: 131 EKILCIGLNYLDHAIETGAEKPSLPVVFSKFNSALVGHGQDIVLPK-ISDKVDYEAELVV 189 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK VD++ A D V GY + D+ + DW+K + Q L+GK+ DTF P+GP +VT+ Sbjct: 190 VIGKTVRHVDANEAMDAVFGYAVGHDVSSRDWQKGRPGGQWLVGKSFDTFAPLGPAVVTA 249 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI +P NL ++ ING Q+S T+Q I IP +IA LS MTL PGD+I TGTP GVG Sbjct: 250 DEISDPGNLPIRLHINGETLQESKTDQLIFDIPALIAHLSKFMTLKPGDLIFTGTPSGVG 309 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFE 52 R PP +L PGD EI+ IG E Sbjct: 310 DARTPPRYLAPGDRCVVEIDGIGRLE 335 >UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase; n=1; Blastopirellula marina DSM 3645|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase - Blastopirellula marina DSM 3645 Length = 284 Score = 204 bits (499), Expect = 1e-51 Identities = 102/208 (49%), Positives = 129/208 (62%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+CVGLNY DH +E T + P IFNKFPS ++ +D I L + S+ V E EL V Sbjct: 75 KVICVGLNYADHAKETGATVGDEPVIFNKFPSALIADHDEIHLPPESSQ-VDYEAELVVA 133 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG + A +V GY DI A DW+K K Q LLGK DTF P+GP + T D Sbjct: 134 IGTAGKHIPQGEAMSHVGGYCCGNDISARDWQKGKPGKQWLLGKTFDTFAPLGPVLYTPD 193 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI +P NL ++C +NG Q+S+T+Q I KI +I+ LSNV+ L PGD+I TGTP GVGV Sbjct: 194 EIADPNNLAIRCRLNGETMQESSTSQLIFKIDFLISYLSNVVMLQPGDLIFTGTPHGVGV 253 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 R+P FLQPGD + EIE +G RV Sbjct: 254 ARDPQVFLQPGDQVEVEIEGLGLLTNRV 281 >UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Planctomyces maris DSM 8797|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Planctomyces maris DSM 8797 Length = 290 Score = 204 bits (498), Expect = 2e-51 Identities = 99/209 (47%), Positives = 133/209 (63%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KVLC+GLNY+DH EE + P+ P F+KF S+V G I++ V++ V E EL V Sbjct: 80 KVLCIGLNYRDHAEETGMPFPDEPVCFSKFSSSVTGSGQPIRIP-SVAREVDYEAELVAV 138 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK V ++A DYV GY D+ A DW+ + Q LLGK DTF P GP++VT+D Sbjct: 139 IGKTCRNVTQANASDYVAGYMNGHDVSARDWQIGRPGGQWLLGKTADTFAPTGPYLVTAD 198 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI N +L++K ++NG Q SNT++FI I ++IA +S ++TL PGDII TGTP GVG+ Sbjct: 199 EIKNANSLSIKLTLNGEVLQNSNTDKFIFTIEEVIAFVSQILTLEPGDIIFTGTPPGVGM 258 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 R PP +LQPGD EI+ +G VE Sbjct: 259 ARKPPVYLQPGDQACIEIQGLGMLHNTVE 287 >UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Ectothiorhodospiraceae|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM 244 / SL1)) Length = 316 Score = 204 bits (497), Expect = 2e-51 Identities = 98/218 (44%), Positives = 131/218 (60%), Gaps = 6/218 (2%) Frame = -3 Query: 678 HGNDKVLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517 H V+C+GLNY DH E + L PE P +F K ++V GP D L V+ Sbjct: 96 HPPRNVICLGLNYADHARESQQAKGDELALPEAPVVFTKATTSVAGPYDDFILDPSVTSE 155 Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337 + E+EL VVIG+ + A +V GYT+ D+ A D + K Q LGK++D C Sbjct: 156 LDWEVELAVVIGRGGRHIREQDALQHVFGYTVVNDLSARDLQFRHK--QFFLGKSVDGSC 213 Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 P+GPWI T++ + NP NL + C IN +Q+S+T + + IP IIA LS VMTL+PGDII Sbjct: 214 PMGPWITTANAVPNPHNLALSCRINDTTEQQSHTGEMVFSIPRIIAELSRVMTLIPGDII 273 Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TGTP GVG R PP FLQ GD++TSE+E +GT R+ Sbjct: 274 ATGTPAGVGFARTPPRFLQAGDIVTSEVEGLGTLRNRI 311 >UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 293 Score = 200 bits (489), Expect = 2e-50 Identities = 102/216 (47%), Positives = 131/216 (60%), Gaps = 7/216 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEE-------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505 V C+G NY H EE Q PE P F+K +TV+GP+D I + S+ + E Sbjct: 74 VFCMGWNYLTHFEEGRGRREGQGEELPEYPTFFDKPTTTVIGPHDDIPFDPNFSEKIDYE 133 Query: 504 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 325 EL VVIG+ + + A D+V GYT A D+ A D ++ Q L GK MD CP+GP Sbjct: 134 AELAVVIGRSGRSIPAGEAMDHVFGYTAANDVTARDVQRRHG-GQWLKGKGMDGSCPLGP 192 Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 WIVT+DEI + QNL V+C +NGVQKQ SNT + + +I LS MTLLPGD++LTGT Sbjct: 193 WIVTADEIPDVQNLQVQCRVNGVQKQNSNTRFMVFPVARLIEELSLAMTLLPGDVLLTGT 252 Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 P GVG R PPEFL+PGD +T +E +G RV E Sbjct: 253 PEGVGYARTPPEFLRPGDEVTVYVEGVGEISNRVVE 288 >UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Oceanobacillus iheyensis|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Oceanobacillus iheyensis Length = 301 Score = 191 bits (465), Expect = 2e-47 Identities = 92/210 (43%), Positives = 132/210 (62%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+CVG NY +H E K PE P +F KF + ++GP + I +++ + E+ELT+V Sbjct: 94 KVICVGKNYAEHVAEMKSEIPEFPVLFAKFDNAIIGPEEEIHYS-SLTEKLDYEVELTIV 152 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++AS V A DYV GYTI D A D +K + Q L GK++D PIGPW+VT D Sbjct: 153 IGREASHVFEEEALDYVAGYTIGNDTSARDLQK--RTPQWLQGKSLDHTTPIGPWVVTKD 210 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI +P NL + +N ++Q SNT I +P +++ +SN++TL PGDII+TGTP GVG Sbjct: 211 EIVDPGNLTIASYVNNEKRQYSNTKHLIFSVPYLVSFISNLITLKPGDIIMTGTPDGVGF 270 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37 +PP +++ D + EIE IG E V++ Sbjct: 271 AMDPPGYVKDKDKVKLEIEGIGIMENMVKK 300 >UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Solibacter usitatus Ellin6076|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Solibacter usitatus (strain Ellin6076) Length = 269 Score = 188 bits (457), Expect = 1e-46 Identities = 95/202 (47%), Positives = 127/202 (62%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+GLNY+DH EE K+ PE P +F K+ +TV G I L + S+ E EL VV Sbjct: 61 KIICIGLNYRDHAEEAKMPIPETPTVFAKWGNTVTGHQHPIVLPKN-SRKPDYEAELAVV 119 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK + ++ ++V GYTI D+ A D++ SQ +GK DTF PIGPWIVT+D Sbjct: 120 IGKGGRHIAEANWREHVFGYTILNDVSARDFQM--ATSQWTIGKTFDTFAPIGPWIVTTD 177 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI +P L + ++N V Q SNT+ I IP +IA LS+VM+L PGDII TGTP GVG Sbjct: 178 EIEDPGALRISLTLNSVTMQDSNTSNLIFGIPKLIAYLSSVMSLEPGDIISTGTPAGVGF 237 Query: 126 YRNPPEFLQPGDVITSEIENIG 61 + PP +L PGDV ++ IG Sbjct: 238 AQKPPRWLVPGDVCAIQVGGIG 259 >UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Opitutaceae bacterium TAV2|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Opitutaceae bacterium TAV2 Length = 279 Score = 188 bits (457), Expect = 1e-46 Identities = 96/208 (46%), Positives = 120/208 (57%), Gaps = 1/208 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-SKAVVCEIELTVV 487 +LC+GLNY+ H EE PE P +F K + + P D I L + S V E EL VV Sbjct: 69 ILCIGLNYRRHAEETHARIPEFPVLFMKGVNALQNPGDPIMLPTHLRSDEVDYECELAVV 128 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+ V HA DYVLGYT A D+ A DW+ + SQ GK DTF P+GP IVT D Sbjct: 129 IGRTCKNVTRDHALDYVLGYTCANDVSARDWQVKRGGSQWCRGKTFDTFAPLGPAIVTKD 188 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI NP L + +++G Q T+ I +P +I LS TLLPG +ILTGTP GVG+ Sbjct: 189 EIPNPNALKISTTVSGEVLQDWTTSDMIFDVPALIEFLSGSTTLLPGTVILTGTPHGVGM 248 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 R PP +L+ GD + EIE IG E V Sbjct: 249 ARKPPRWLRAGDKVVVEIEKIGRLENPV 276 >UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Acidobacteria bacterium Ellin345|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Acidobacteria bacterium (strain Ellin345) Length = 290 Score = 186 bits (452), Expect = 6e-46 Identities = 95/209 (45%), Positives = 128/209 (61%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ +GLNY DH +E + P+ P F KF S++ GP D I+L D V E EL VV Sbjct: 82 KIVAIGLNYLDHAKEAGQSIPKTPLCFAKFTSSLSGPYDPIRLP-DAEAQVDFEGELGVV 140 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK+A +V S A +YV GY + D+ ++ Q GK+ DTF P GP++VT D Sbjct: 141 IGKRAHRVAESEAMEYVAGYVVFNDV--SERRSQFADGQWTRGKSCDTFSPNGPYLVTRD 198 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +P NL + +NG Q SNTNQ I KIP++I+ LS+ T PGDII TGTP GVG Sbjct: 199 EVADPGNLRITTRVNGAVMQDSNTNQLIFKIPELISYLSHSFTFHPGDIIATGTPPGVGF 258 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 R PP +L+ GD++ EIE++G RVE Sbjct: 259 SRKPPLYLREGDLVEVEIESVGRIANRVE 287 >UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=6; Burkholderiales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Burkholderia cenocepacia (strain HI2424) Length = 293 Score = 186 bits (452), Expect = 6e-46 Identities = 98/220 (44%), Positives = 134/220 (60%), Gaps = 11/220 (5%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLT-----------PPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517 + CVG NY +H E + + PE P IF K STV+GP+ I + V+ Sbjct: 77 IFCVGKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTVIGPSAKIPRHVGVTAQ 136 Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337 + E EL VVIGK + + A +YV GYT+ D A D +K + Q LGK++D FC Sbjct: 137 LDYEAELGVVIGKGGRGIKKADAMNYVFGYTVINDFTARDLQKLHR--QWFLGKSLDGFC 194 Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 P+GP+++TSDE+ N QN+++KC +NG +Q SNT++ I IP +I LS + L PGD+I Sbjct: 195 PMGPFVITSDEV-NGQNIDIKCWVNGELRQNSNTSKLIFDIPTLIETLSAGIELQPGDVI 253 Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 TGTP GVG+ NPP+FLQ GDVI EI+N+G E V E Sbjct: 254 ATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE 293 >UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Bacillus clausii KSM-K16|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Bacillus clausii (strain KSM-K16) Length = 292 Score = 183 bits (445), Expect = 4e-45 Identities = 92/211 (43%), Positives = 133/211 (63%), Gaps = 2/211 (0%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K++C+GLNY+ H +E PE P +F+KF +T+ G I + V++A+ E+EL + Sbjct: 81 EKIICIGLNYRRHADETGSPYPETPILFSKFNNTLTGHGSNIVVP-PVTQALDYEVELAI 139 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK A +V A +YVLGY A D+ A D + K +Q LLGK D FCPIGP++VT Sbjct: 140 VIGKTAKQVTEDEALNYVLGYCTANDLSARDLQM--KTAQWLLGKTCDGFCPIGPFLVTK 197 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV- 133 ++I +PQNL ++ +NG KQ+SNT I +II+ +S TL PGDI+LTGTP GV Sbjct: 198 EDIADPQNLALETRVNGEIKQQSNTADMIFTCAEIISYVSRHFTLKPGDILLTGTPEGVI 257 Query: 132 -GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G+ +LQPGD ++ IE +GT ++ Sbjct: 258 LGLPEAERRYLQPGDTVSVHIEQLGTLTNKL 288 >UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 295 Score = 182 bits (442), Expect = 1e-44 Identities = 89/210 (42%), Positives = 130/210 (61%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ +GLNY+DH E PE P +F K+ +T+VG + +++ S+A E EL VV Sbjct: 87 KIIAIGLNYEDHANETGAPIPEKPIVFAKYANTLVGAGEEVRIPPITSQADY-EAELAVV 145 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++A V A +YV GYT D+ + D + ++ Q K++DTFCP+GP++ T D Sbjct: 146 IGREAKNVSEEEALEYVFGYTNCNDVSSRDLQFSEG-GQWTRSKSLDTFCPLGPYVATRD 204 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI +PQ+L ++ +NG Q SNT++ I + +I+ LS MTL+PGDII TGTP GVG Sbjct: 205 EIPDPQSLRIRSVLNGEVMQDSNTSKMIFPVARLISFLSTGMTLVPGDIIATGTPAGVGF 264 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37 R+P FL+ GD I+ EIE +G V E Sbjct: 265 ARDPKVFLKDGDEISIEIEGLGRLTNPVRE 294 >UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 302 Score = 181 bits (440), Expect = 2e-44 Identities = 92/210 (43%), Positives = 126/210 (60%), Gaps = 6/210 (2%) Frame = -3 Query: 654 VGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 +GLNY +H E P+ P IF+K P+ V ND I+ V++ + E EL Sbjct: 93 IGLNYTEHVAESARALDTAHELPQQPVIFSKPPTAVAAWNDPIRHNAKVTQQLDWETELA 152 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 V+IG A V + A ++V GYT+ D+ A D ++ Q ++ K D+F P+GP IVT Sbjct: 153 VIIGSTARGVAEADALNHVFGYTVINDVSARDC---RRAGQWIVSKGQDSFAPMGPCIVT 209 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 +DEIG+P NLN+ +NGV+KQ SNT + +P +IA ++ VMTL PGDII TGTP GV Sbjct: 210 ADEIGDPHNLNILTHVNGVEKQNSNTRFMLFNVPQLIADIARVMTLEPGDIIATGTPAGV 269 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G R+P EFL PGDV+ +E IGT V Sbjct: 270 GAGRDPQEFLWPGDVVECTVEGIGTLRNPV 299 >UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family protein; n=2; Candidatus Pelagibacter ubique|Rep: Fumarylacetoacetate hydrolase family protein - Pelagibacter ubique Length = 281 Score = 180 bits (438), Expect = 3e-44 Identities = 86/204 (42%), Positives = 129/204 (63%) Frame = -3 Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475 +GLNY +H +E P+ P +FNK ++VGPND + + SK + E+E+ VIGKK Sbjct: 76 IGLNYVEHAKETGAKTPDNPVLFNKSVHSIVGPNDNVIIPK-TSKKLDHEVEIAFVIGKK 134 Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 295 A +V A DY+ GY I DI +W+K K Q + GK+ DTF P+GP++VT DEI + Sbjct: 135 AKRVLEKDAQDYIFGYCICNDISEREWQKEKG-GQWVKGKSGDTFGPLGPYLVTKDEIQD 193 Query: 294 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115 NLN+ +NG + Q NTNQ I ++A +++ +TL+PGDI+ TGTP GVG+ +P Sbjct: 194 VNNLNLTLDVNGHRHQTGNTNQMIFNFNFLVAHITSFITLMPGDIVTTGTPPGVGLGMDP 253 Query: 114 PEFLQPGDVITSEIENIGTFETRV 43 P FL+ GD + I+++G+ ++V Sbjct: 254 PVFLKEGDEMKLNIDSLGSQNSKV 277 >UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Bacillus sp. B14905|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus sp. B14905 Length = 314 Score = 177 bits (432), Expect = 2e-43 Identities = 84/204 (41%), Positives = 125/204 (61%), Gaps = 2/204 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 ++C+G NY +H +E + P EL +F K P+ + T+ + D+S + E EL + Sbjct: 94 IMCIGKNYNEHAKEMGAEAAPKEL-MVFTKSPTAIAADGQTLSIHADLSSKMDYEGELAI 152 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK+ + + A+DYV GYTIA DI A D ++ K Q LGK+++ CP+GP++VT Sbjct: 153 VIGKRGKNIPKNLAYDYVFGYTIANDITARDLQEKHK--QFFLGKSLEGTCPLGPYLVTK 210 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI NPQ+L V +N +Q +T + + +++ LS +TL PGD+ILTGTP GVG Sbjct: 211 DEIPNPQDLTVVTKVNDEVRQNGSTKDMMFSVETLVSILSQHVTLEPGDVILTGTPAGVG 270 Query: 129 VYRNPPEFLQPGDVITSEIENIGT 58 NPP+FL+ GD + I+ IGT Sbjct: 271 KGMNPPQFLKAGDTVKVSIQGIGT 294 >UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Symbiobacterium thermophilum|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Symbiobacterium thermophilum Length = 294 Score = 177 bits (431), Expect = 2e-43 Identities = 89/208 (42%), Positives = 128/208 (61%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+LCVGLNY+ H E + P P +F KF + V GP D + L +++ E EL VV Sbjct: 86 KILCVGLNYRAHAAEAHMAVPAYPVLFAKFQNAVAGPGDPVVLP-SIAEQYDYEAELVVV 144 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++A +V + A DYVLGY D+ A E + SQ LLGK++D F PIGP++VT D Sbjct: 145 IGRRARRVPAEAALDYVLGYCNGNDLSAR--ELQMRTSQWLLGKSLDGFLPIGPYLVTRD 202 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +PQ+L ++ NG +Q +T + + ++IA +S MTL PGDII TGTP GV + Sbjct: 203 EVPDPQDLRIRLWRNGEIRQDGHTRNMLFPVAELIAYISRYMTLEPGDIIATGTPEGVIM 262 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 ++L+PGDV+ EI+ +G E R+ Sbjct: 263 GLAEKDWLKPGDVVAVEIDGLGRLENRL 290 >UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=8; cellular organisms|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Thermoanaerobacter tengcongensis Length = 242 Score = 176 bits (429), Expect = 4e-43 Identities = 100/209 (47%), Positives = 129/209 (61%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K +CVGLNYKDH EE PE P +F K + V+GP+D I L ++S+ V E EL VV Sbjct: 47 KAICVGLNYKDHIEEMGDKIPEEPTLFIKPSTAVIGPDDYIILP-EMSRRVDYEGELAVV 105 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+KA V A +Y+LGYTIA D+ A D + K Q K+ DTF PIGPWIVT Sbjct: 106 IGRKAKNVSIEEAKNYILGYTIANDVTARDLQA--KDGQWTRAKSFDTFLPIGPWIVTDL 163 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + P +LN+ +NG KQKSNT I + +++ +S++MTL PGD+ILTGTP GVG Sbjct: 164 D---PTSLNITTYVNGEVKQKSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGP 220 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 L+ GDV+T EIE IG RV+ Sbjct: 221 -------LKSGDVVTIEIEGIGKLTNRVK 242 >UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=3; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Neptuniibacter caesariensis Length = 286 Score = 175 bits (425), Expect = 1e-42 Identities = 95/208 (45%), Positives = 119/208 (57%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K L VGLNY DH EE L PE P FNK S V+GPN+ I + VS+ + E EL +V Sbjct: 74 KFLGVGLNYADHIEETGLDTPEFPTFFNKQSSCVIGPNEAIH-RPTVSEKLDYEGELAIV 132 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK V A + + G+TI D+ DW+ K LGK+ DT P+GPWIVT+D Sbjct: 133 IGKACRHVPYEKASEVIAGFTIVNDVSVRDWQI--KSPTWTLGKSFDTHGPMGPWIVTAD 190 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ NP NL +K +N +Q SNT I +I LS V TL PGD+I TGT GVGV Sbjct: 191 EV-NPHNLELKTWVNDELRQHSNTKHLIFDCYQLIETLSTVCTLQPGDVIATGTSSGVGV 249 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 P +++PGD +T EIE IG V Sbjct: 250 KMKPRGYMKPGDRVTIEIEGIGKLSNPV 277 >UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; n=1; Pedobacter sp. BAL39|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase - Pedobacter sp. BAL39 Length = 285 Score = 175 bits (425), Expect = 1e-42 Identities = 86/211 (40%), Positives = 123/211 (58%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+GLNY DH E P P +F K + +VGP D I + K E+EL +V Sbjct: 74 KLVCIGLNYADHARETNAPLPPEPVVFMKSTTAIVGPFDQIMIPKGSVKTD-WEVELAIV 132 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGKKAS V+ + A DYV GY + D+ +++ + GK DTF P+GP++ T + Sbjct: 133 IGKKASYVEEAEALDYVAGYVLHNDVSEREFQIERN-GTWDKGKGCDTFAPLGPFLATKE 191 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI + NL + S+NG Q NT+ FI +P +++ +S MTLLPGD+I TGTP GVG+ Sbjct: 192 EIADVNNLRLWLSVNGKMMQDGNTSNFIFNVPFVVSYVSQFMTLLPGDVISTGTPAGVGL 251 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34 PP +L+ GDV+ I+ +GT V F Sbjct: 252 GFKPPVYLKAGDVVELGIDGLGTSRQEVIAF 282 >UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Roseiflexus|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Roseiflexus sp. RS-1 Length = 288 Score = 174 bits (423), Expect = 2e-42 Identities = 91/213 (42%), Positives = 123/213 (57%), Gaps = 6/213 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V+C+G+NY H E ++ PE P F K TV GP+D I L V+ + E+ Sbjct: 74 VICLGMNYVAHTIESYRARGREPKMPEYPVFFTKAAHTVCGPDDDIPLDPKVTNELDYEV 133 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL +IGK V A +YV GYTI DI A D + + Q GK++ CP+GP Sbjct: 134 ELAFIIGKAGMNVPRDEAMEYVFGYTIVNDISARDLQSRHQ--QFFKGKSLYRACPMGPC 191 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 IVT+DEI NP L ++ +NG +Q S+T I IP II LS M L PG I+ TGTP Sbjct: 192 IVTTDEIPNPAGLGIRLRLNGETRQDSHTGDLIFDIPAIIEHLSLGMPLEPGMIVATGTP 251 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GVG+ R PPE+++PGDV+ +EI++IG R+ Sbjct: 252 AGVGLGRTPPEYMRPGDVMEAEIDSIGILRNRI 284 >UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase precursor; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 349 Score = 174 bits (423), Expect = 2e-42 Identities = 89/215 (41%), Positives = 123/215 (57%), Gaps = 8/215 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508 + CVG NY DH EE P++P +F K T+ GP D I +S + Sbjct: 135 IYCVGWNYLDHFEEGLKHRADTAVKEYPKVPVLFTKGTQTMNGPFDNIPYDAGISTMIDW 194 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E EL VVIGKK + +A DYV GY+ D A D ++ ++ Q GK++D P+G Sbjct: 195 EAELAVVIGKKGKNISEENAMDYVFGYSAYNDTTARDIQQKRQSGQWFKGKSLDGHGPMG 254 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 PW+VT+ + N + + CS+NGV+KQ ++ Q KIP IIA LS +TLLPGDII TG Sbjct: 255 PWVVTAGGV-NLDDTRIICSVNGVEKQNASYKQMYFKIPAIIAELSRGLTLLPGDIIATG 313 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TP GVG R P EF++PGD++ + I IG ++ Sbjct: 314 TPSGVGAGRTPQEFMKPGDMMETNITGIGILRNKI 348 >UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Dinoroseobacter shibae DFL 12 Length = 308 Score = 173 bits (422), Expect = 3e-42 Identities = 91/213 (42%), Positives = 123/213 (57%), Gaps = 6/213 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 + CVG NY +H E K+ E P F K + VVG + + VS+ + E+ Sbjct: 94 IFCVGRNYAEHIAEGERAQNAKIGITEHPVYFTKPATAVVGHGGDVLIFPSVSEKIDYEV 153 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL VVIG + AF +V GYTI DI A D ++ Q GK++D CPIGPW Sbjct: 154 ELAVVIGTTGRDIPKDRAFAHVFGYTILNDITARDVQRRHG-GQYFKGKSLDGSCPIGPW 212 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 IVT+DEI +PQ+L++ S+NG +Q T+ I IP +IA LS +TL PGDII TGTP Sbjct: 213 IVTADEITDPQDLSISLSVNGELRQNGWTHDMIFDIPTLIASLSEGLTLEPGDIIATGTP 272 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GVG +PP++L+PGD + +I NIG + V Sbjct: 273 SGVGYAMDPPQYLKPGDTVICDIANIGQLKNTV 305 >UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; Staphylococcus|Rep: Uncharacterized protein SH1982 - Staphylococcus haemolyticus (strain JCSC1435) Length = 301 Score = 173 bits (421), Expect = 3e-42 Identities = 87/209 (41%), Positives = 122/209 (58%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 + V+ G NY+DH E L ++F K S++ G TI D++ + E EL + Sbjct: 93 NNVIAFGRNYQDHASELNHEVQRL-YVFTKAASSLTGDESTIPNHKDITDQLDYEGELGI 151 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK K+ + A DY+ GYTI DI TD + + Q L K++ CP+GP+IVT Sbjct: 152 VIGKSGEKIPKALALDYIYGYTIINDI--TDRKAQNEQDQAFLSKSLTGGCPMGPYIVTK 209 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DE+ P+N+N+ +N +Q NT+Q I+KI D+I +S + L PGDII TGTP GVG Sbjct: 210 DELPTPENVNIVTKVNNDIRQDGNTSQMINKIDDLIEEISKYVALHPGDIIATGTPAGVG 269 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 PP+FLQPGD + I+NIGT T + Sbjct: 270 AGLQPPQFLQPGDEVKVTIDNIGTLTTYI 298 >UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family protein; n=21; Firmicutes|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus anthracis Length = 302 Score = 172 bits (419), Expect = 6e-42 Identities = 88/210 (41%), Positives = 123/210 (58%), Gaps = 2/210 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +LCVG NY++H E PE IF K P+TV+G ++ I + + E EL + Sbjct: 95 ILCVGKNYREHAIEMGGVESIPENIMIFTKAPTTVIGMDEKINSHPHATNELDYEGELAI 154 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK+ ++ A ++V GYTI DI A D ++ K Q LGK+ DTFCP+GP+++ Sbjct: 155 VIGKRGKQIKKEKALEHVFGYTIINDITARDIQRKHK--QFFLGKSFDTFCPMGPYLIHK 212 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 I P L+++ +NG +Q SNTN+ I I +II+ +S MTL PGDII TGTP GVG Sbjct: 213 SMISTPNALHIETIVNGEVRQTSNTNKMIFSIEEIISTISKGMTLEPGDIIATGTPAGVG 272 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40 PP+FL GD + +E IGT V+ Sbjct: 273 KGFTPPKFLHAGDEVVITVEGIGTLRNVVK 302 >UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=4; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Silicibacter sp. (strain TM1040) Length = 281 Score = 172 bits (419), Expect = 6e-42 Identities = 84/202 (41%), Positives = 121/202 (59%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K +C+GLNY DH E ++ PE P IF K S + GPND +++ S E+EL VV Sbjct: 72 KFICIGLNYADHAAESGMSLPEEPVIFFKATSAICGPNDAVEIPR-TSVKTDWEVELGVV 130 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK A + A D+V GY + D+ D++ ++ Q + GK+ DTF PIGPW+VT D Sbjct: 131 IGKTAKYIGRDEALDHVAGYCVVNDLSERDFQLHRS-GQWVKGKSADTFGPIGPWLVTRD 189 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +PQNL + +NG + Q +T + +I+ LS M+L PGD+I TGTP GVG+ Sbjct: 190 EVPDPQNLAMWLEVNGHRYQDGSTRTMHFDVATVISHLSQFMSLQPGDVISTGTPPGVGM 249 Query: 126 YRNPPEFLQPGDVITSEIENIG 61 + P +L+PGDV+ I +G Sbjct: 250 GQTPETYLKPGDVMELGIAGLG 271 >UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=13; Proteobacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Rhodopseudomonas palustris Length = 280 Score = 171 bits (417), Expect = 1e-41 Identities = 83/207 (40%), Positives = 123/207 (59%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V G K + +GLNY DH E + P P +F K +++ GPND ++ K S + E+ Sbjct: 67 VGGAPKFIAIGLNYADHAAEANMPIPAEPIVFMKAINSLCGPNDDVE-KPRGSTKLDWEV 125 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL V+IG +A V + A +YV GY + D+ +++ ++ Q GK+ DTF P+GPW Sbjct: 126 ELAVIIGTRAKYVTEADALNYVAGYAVCNDVSERNFQL-ERAGQWTKGKSHDTFGPLGPW 184 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 + T DEI + L + +NG ++Q +T I +P I++ LS +MTL+PGDII TGTP Sbjct: 185 VATKDEIADVHKLGMWLDVNGQRRQTGSTATMIFNVPKIVSYLSELMTLMPGDIITTGTP 244 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIG 61 GVG PP++L GDV+T IE +G Sbjct: 245 PGVGTGMKPPQYLNVGDVVTLGIEGLG 271 >UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Parvibaculum lavamentivorans DS-1 Length = 291 Score = 171 bits (417), Expect = 1e-41 Identities = 88/208 (42%), Positives = 116/208 (55%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KVL +GLNY+DH EE PE FNK + + GP I L VS + E E+ V Sbjct: 75 KVLAIGLNYRDHVEESGQPMPEHQVWFNKQHNCITGPYADIALP-SVSAFLDYEAEMCFV 133 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK+ V A + + GY + D+ DW+ Q+ GK+ DT PIGPWIVT D Sbjct: 134 IGKRCKHVPKERAHEVIAGYFVGDDVSVRDWQLRTNTWQI--GKSFDTHGPIGPWIVTPD 191 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+G+P L++KC +NG +Q SNT I D IA L+ TL GD+I TGT GG+G Sbjct: 192 EVGDPHALDIKCWVNGELRQNSNTKHLIFDCFDQIAHLTQAFTLDIGDVIFTGTSGGIGA 251 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 P + L+ GDV+ E+E +G E RV Sbjct: 252 AMKPMQLLKEGDVVRVEVEKLGYIENRV 279 >UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Euryarchaeota|Rep: Uncharacterized protein MJ1656 - Methanococcus jannaschii Length = 237 Score = 171 bits (417), Expect = 1e-41 Identities = 92/210 (43%), Positives = 126/210 (60%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNY DH +E + PE P IF K S ++ D I ++ +SK V E+EL +V Sbjct: 39 KIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYI-IRPRISKRVDYEVELAIV 97 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGKK + A DY++GYTI D+ A D ++ K Q K+ DTFCPIGP IV Sbjct: 98 IGKKCKNIKKDEANDYIMGYTILNDVTARDLQQ--KDGQWTRAKSFDTFCPIGPRIVKDI 155 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + P NLN++C +NG KQKSNT I + +++ ++++MTL PGDII TGTP GVG Sbjct: 156 D---PMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVGE 212 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37 L+ GDV+ EIE IG V++ Sbjct: 213 -------LKAGDVVECEIEGIGILRNYVKD 235 >UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family protein; n=8; Proteobacteria|Rep: Fumarylacetoacetate hydrolase family protein - Silicibacter pomeroyi Length = 305 Score = 171 bits (416), Expect = 1e-41 Identities = 82/210 (39%), Positives = 131/210 (62%), Gaps = 6/210 (2%) Frame = -3 Query: 654 VGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 +GLNY +H E + P+ P +F+K P++V+ + I+ +++ + E+EL Sbjct: 94 IGLNYVEHVAESAKSLDTSKELPKEPVVFSKPPTSVIASGEGIQHNAAMTQQLDWEVELA 153 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 V+IGK+A+++ +A +V GY++ D+ A D N++ Q + K DTFCP GP I+T Sbjct: 154 VIIGKRATRIAKDNAMSHVFGYSVINDVSARD---NRRAGQWIFSKGQDTFCPFGPAIIT 210 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 +D++ +P NL++ + NGV+KQ+SNT + IP +IA +S+ +TL PGDII TGTP GV Sbjct: 211 ADDVPDPHNLDLWLTKNGVEKQRSNTRHLLFDIPTLIADISSGITLEPGDIIATGTPAGV 270 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G R+P E++ PGDVI ++ IG V Sbjct: 271 GAGRDPQEWMWPGDVIECGVDGIGVLRNPV 300 >UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4; Thermoprotei|Rep: Fumarylacetoacetate (FAA) hydrolase - Sulfolobus acidocaldarius Length = 307 Score = 170 bits (413), Expect = 3e-41 Identities = 91/214 (42%), Positives = 127/214 (59%), Gaps = 3/214 (1%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K+ + +NY+ H +E PP+ P+IF KF +T++G N + L S V EIEL V Sbjct: 95 EKIFLLAVNYRAHGQETNNNPPKEPYIFTKFNNTLIGHNQPV-LFPRASNKVDYEIELAV 153 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---QLLLGKAMDTFCPIGPWI 319 ++GK+A V+SS A DYV GYTI DI D + +I + + GK +DT P+GPWI Sbjct: 154 IMGKRAKYVNSSKALDYVFGYTIFNDISFRDKQFPPEIPYGMRWVHGKGLDTAAPMGPWI 213 Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 VT DEI N NL +K +NG +Q + I K+ II LSN +TL PGD+I TGTP Sbjct: 214 VTKDEIDNINNLRLKLRVNGEIRQDAYAEDMIFKVEQIIEYLSNGITLKPGDVISTGTPS 273 Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 GV + ++L+PGDV+ +EI IG + E Sbjct: 274 GVALATG--KYLKPGDVMEAEISKIGVLRNNLIE 305 >UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase family protein; n=2; Arthrobacter|Rep: Putative fumarylacetoacetate hydrolase family protein - Arthrobacter nitroguajacolicus Length = 299 Score = 169 bits (411), Expect = 5e-41 Identities = 89/208 (42%), Positives = 122/208 (58%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+C GLNY DH +E P+ P +F K+ T+VG +D I + S V E EL VV Sbjct: 75 KVICCGLNYGDHIQEMGRALPDYPTLFAKYADTLVGASDPIYVHG--SDKVDWEAELAVV 132 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG +VD A + GYT+A D+ DW+ N+ + Q GKA D P+GP ++T+D Sbjct: 133 IGSNLYRVDEDQALAGIAGYTVANDVSMRDWQ-NRTL-QWFQGKAFDATTPLGPVMLTAD 190 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E P + +V +NG Q QK NT+ + ++A +S L PGD++LTGTPGGVG+ Sbjct: 191 EA--PADFDVYGYVNGEQVQKGNTSTLVFGPARLVAYISQFTMLRPGDVVLTGTPGGVGM 248 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 NPP FL GDV+T+EI IG E R+ Sbjct: 249 GMNPPRFLSDGDVLTTEIPGIGRLENRI 276 >UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative fumarylacetoacetate hydrolase - Aurantimonas sp. SI85-9A1 Length = 293 Score = 168 bits (409), Expect = 1e-40 Identities = 89/218 (40%), Positives = 126/218 (57%), Gaps = 9/218 (4%) Frame = -3 Query: 663 VLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 511 + CVG NY++H E K P P IF K S ++GP TI+ +D ++ V Sbjct: 78 IFCVGKNYREHASEFHNSGFDSGGKQAIPVAPVIFTKSLSAIIGPGATIEAGLDRTRTVD 137 Query: 510 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 331 E EL VVIGK+A V + A DYV GY + D+ T E + SQ ++GK +DTF P+ Sbjct: 138 YEGELGVVIGKRAFGVTKADAMDYVFGYVVINDV--TSRELQRHHSQWVIGKGIDTFAPM 195 Query: 330 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151 GP +VT+DE+ + L V ++NG +QK++ I IP +I ++ MTLLPGDII T Sbjct: 196 GPVLVTADEVPDVTKLTVTTTVNGETRQKASVAGLIFDIPTLIETMTATMTLLPGDIIAT 255 Query: 150 GTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 GTP GVG+ +PP +L GD + I+ +GT E V + Sbjct: 256 GTPAGVGIGFDPPRYLADGDRVAVTIDGLGTLENPVRQ 293 >UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Picrophilus torridus|Rep: Fumarylacetoacetate hydrolase family protein - Picrophilus torridus Length = 281 Score = 168 bits (409), Expect = 1e-40 Identities = 91/209 (43%), Positives = 127/209 (60%), Gaps = 1/209 (0%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKMDVSKAVVCEIELT 493 +K++CVG NYK+H E PE P +F+KF +T+ G ND I +D S ++ E EL Sbjct: 72 EKIICVGKNYKEHALETGSGIPESPVLFSKFNNTLTGHLNDII---IDFSDSIDYEGELG 128 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 +VIGKKA VD + A DYV GY IA D+ A D + + SQ LLGK D F P GP+IVT Sbjct: 129 IVIGKKARNVDENDAMDYVFGYYIANDVSARDLQY--RTSQWLLGKTPDGFYPNGPFIVT 186 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 DE+ +P NL+++ NG Q SNT I I +I +S +TL+PGD+I TGTP GV Sbjct: 187 KDEVNDPMNLDIRTLRNGDTVQHSNTRNMIFDIKYLIGYISKYLTLMPGDVISTGTPEGV 246 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETR 46 + N +++ + I +IE +G+ + R Sbjct: 247 ILGTNEKNWIKNNETIEVKIEKLGSLKNR 275 >UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Rep: Blr5285 protein - Bradyrhizobium japonicum Length = 283 Score = 167 bits (407), Expect = 2e-40 Identities = 84/208 (40%), Positives = 122/208 (58%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNY+DH E E P +F +FP + VG I +K VS E EL +V Sbjct: 74 KIICVGLNYRDHVAETGRIVTEKPALFVRFPCSQVGHLQPI-VKPKVSDDFDYEGELALV 132 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK+ + ++ A D++ GY+ + DW+++ SQ L GK GPW+VT+D Sbjct: 133 IGKEGRHIPANRALDHIAGYSCYNEGSVRDWQRHT--SQFLSGKTFAESGSFGPWLVTAD 190 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI +P L ++ +NG Q + T+ I IP +IA +S + L+PGD+I+TGTPGGVG Sbjct: 191 EIPDPSKLTLQTRLNGTVVQDTTTDLLITAIPGLIAYISTICPLVPGDVIVTGTPGGVGA 250 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 R PP +++PGD + EI IGT +V Sbjct: 251 KRTPPLWMRPGDTVEVEISGIGTLRNKV 278 >UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=4; Archaea|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Methanobacterium thermoautotrophicum Length = 260 Score = 167 bits (407), Expect = 2e-40 Identities = 87/209 (41%), Positives = 127/209 (60%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+CVGLNY+DH E + P+ P IF K P+TV+G DT+ + ++S V E+EL V Sbjct: 59 KVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTV-IYPEMSSEVDYEVELAAV 117 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 + ++A +VDSS A +++ GYT+ D+ A D ++ Q K+ DTFCPIGP I T Sbjct: 118 VSERARRVDSSAASEFIAGYTVLNDVTARDLQRRD--GQWTRAKSFDTFCPIGPVIETDV 175 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 P NL++ +NG +Q SNT+ I + +++ +S+VMTL PGD+I TGTP GVG Sbjct: 176 ---TPDNLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEPGDVIATGTPPGVGQ 232 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 + PGD + + +E +GT RVE Sbjct: 233 -------MVPGDTVRATVEGVGTLVNRVE 254 >UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Alkaliphilus metalliredigens QYMF|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Alkaliphilus metalliredigens QYMF Length = 298 Score = 167 bits (406), Expect = 2e-40 Identities = 82/207 (39%), Positives = 121/207 (58%), Gaps = 6/207 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V+C+GLNYK H E + + PE P F K + +GP + I +++ V E+ Sbjct: 87 VICLGLNYKAHVAESQSALSAGIKMPEFPVYFTKMSTQAIGPQEAINSHPQITQEVDYEV 146 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL V+IGK + + D++ GYTI D+ A D ++ +Q + GK++DTF +GPW Sbjct: 147 ELAVIIGKGGTNIPPEEVQDHIFGYTILNDVSARDLQRRH--NQWVKGKSLDTFTVMGPW 204 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 I+ + I P L++ +NG +Q SNT FI IP +I+ LS +TL GD+I TGTP Sbjct: 205 IMEKETISLPVELDLYSKVNGEIRQHSNTKDFIFDIPTVISELSKGLTLEAGDVIATGTP 264 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIG 61 GVG+ NPP++L+ GDV+ IE IG Sbjct: 265 AGVGMGFNPPKYLKAGDVVECYIEKIG 291 >UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctional decarboxylase/isomerase; n=4; Pezizomycotina|Rep: Function: E. coli hpaG is a bifunctional decarboxylase/isomerase - Aspergillus niger Length = 358 Score = 167 bits (405), Expect = 3e-40 Identities = 90/211 (42%), Positives = 125/211 (59%), Gaps = 1/211 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 V+C+GLNYK H +E L P P +F K + GP +TI + D + E ELTVVI Sbjct: 64 VICIGLNYKQHAKEASLDVPTYPPVFTKPADVLAGPFETIPIHRDAQSHLDYEGELTVVI 123 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI-SQLLLGKAMDTFCPIGPWIVTSD 307 GK A V + A DYVLGYT D+ A +++ + Q K+ D F PIG +V++ Sbjct: 124 GKDAKNVSAEDALDYVLGYTAGNDLSARNFQMPEASGGQFCYAKSFDKFAPIGHVLVSAQ 183 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +PQ L++ +NGV KQ +NT+ I + DI++ LS MTL G +I+TGTP GVG Sbjct: 184 EVQDPQQLSLVTKVNGVVKQTTNTSDMIWGVRDIVSHLSRGMTLRKGTLIMTGTPSGVGF 243 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34 +R EFLQ GDV+ E+E +G E V +F Sbjct: 244 FRK--EFLQDGDVV--EVE-LGVREPGVIDF 269 >UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=5; Thermoprotei|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Pyrobaculum islandicum (strain DSM 4184 / JCM 9189) Length = 310 Score = 166 bits (403), Expect = 5e-40 Identities = 83/217 (38%), Positives = 128/217 (58%), Gaps = 6/217 (2%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K+LCV +NY++H E + PP+ P+ F KFP+ +VG + +K V + + E+EL V Sbjct: 96 EKILCVAVNYREHGAETGIEPPDKPYFFPKFPNALVGHEGYV-VKHRVVQKLDWEVELVV 154 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQL----LLGKAMDTFCPIG 328 V+G+ ++ A DYV GYT+ D+ DW+ K Q + GK MDT P+G Sbjct: 155 VMGRPGKYIEPERALDYVFGYTVGLDMSMRDWQNPDEKTARQYGKNWIWGKTMDTAAPVG 214 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 P+I T DE+ +P L ++ +NG +Q+ NT+Q I I +I S +TL PGD+I TG Sbjct: 215 PYIATRDEVPDPNRLGLRLWVNGQLEQEGNTSQLIFNIQQLIYWASQGITLRPGDLIFTG 274 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 TP GVG + +FL+ GD++ +E+E+IG + E Sbjct: 275 TPPGVGWAKG--KFLKGGDIVEAEVESIGRLRAYIIE 309 >UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; Clostridium kluyveri DSM 555|Rep: Putative uncharacterized protein - Clostridium kluyveri DSM 555 Length = 301 Score = 165 bits (401), Expect = 9e-40 Identities = 91/213 (42%), Positives = 122/213 (57%), Gaps = 6/213 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V C+G NY++H E KLT P++P F K S +G D+I+ +V+ V E+ Sbjct: 86 VFCLGKNYEEHAREIKLTRITGNEIPKVPIYFTKVASPAIGNGDSIEFSSEVTNQVDYEV 145 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL VVIGK + A Y+ GYTI DI A D + + Q GK++DTFCP+GP Sbjct: 146 ELGVVIGKNGKNIKKEEAEKYIFGYTIINDISARDLQGSH--IQWFKGKSLDTFCPMGPC 203 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 IV +EI P NL++KC +N +Q SNT I IP II+ LS ++L GDII TGTP Sbjct: 204 IVHKNEIPFPINLDIKCWVNEELRQDSNTKNLIFDIPYIISDLSKGVSLKAGDIIATGTP 263 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GVG+ +P + L+ GD I IE IG+ V Sbjct: 264 SGVGMGFSPIKVLKQGDSIECYIEKIGSLVNNV 296 >UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Polynucleobacter sp. QLW-P1DMWA-1 Length = 299 Score = 165 bits (401), Expect = 9e-40 Identities = 80/205 (39%), Positives = 122/205 (59%), Gaps = 3/205 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM-DVSKAVVCEIELTV 490 K++CVGLNY+ H +E + P +P +FNK+ +++ N +++ VS + E EL + Sbjct: 88 KIVCVGLNYRAHADEVGMVHPRVPPLFNKYNNSLAAHNCLLQIPPPSVSYKLDYETELLI 147 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK+ V S A DYV GY + D + D + Q ++GK +D + PIGP+ VT Sbjct: 148 VIGKQMRNVPESAALDYVAGYCTSNDFSSRDLQLELPSGQWMIGKTLDQYAPIGPYFVTG 207 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV- 133 D +GNP NL VK +NG +Q SNT+ FIH +++ +S L PGDI+ TGTP GV Sbjct: 208 DLVGNPNNLQVKTWVNGELRQNSNTSDFIHNTQKMLSYISTYWALEPGDIVFTGTPQGVI 267 Query: 132 -GVYRNPPEFLQPGDVITSEIENIG 61 G+ ++ +L+ GD + S +E +G Sbjct: 268 AGMPKDKQVWLKKGDKVVSSVEKLG 292 >UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Acidovorax sp. (strain JS42) Length = 281 Score = 165 bits (400), Expect = 1e-39 Identities = 82/208 (39%), Positives = 120/208 (57%), Gaps = 1/208 (0%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V G K++CVGLNY DH E L P P +F K S + GP D +++ K E+ Sbjct: 67 VGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPPGALKTD-WEV 125 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL +VIG + +V + A +V GY +A D+ ++ + Q GK DTF P+GPW Sbjct: 126 ELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERG-GQWDKGKGCDTFAPVGPW 184 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 +VT+DEI +P + + +NG + Q +T FI +P ++A +S MTL PGD++LTGTP Sbjct: 185 LVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLEPGDLVLTGTP 244 Query: 141 GGVGVYRNP-PEFLQPGDVITSEIENIG 61 GVG+ + P P FL+ GDV+ +G Sbjct: 245 AGVGLGQKPTPRFLRAGDVMRLGATGLG 272 >UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=2; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 287 Score = 164 bits (399), Expect = 2e-39 Identities = 86/214 (40%), Positives = 117/214 (54%), Gaps = 8/214 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508 + CVG NY H +E P P +F K P VVGP D + L VS+ + Sbjct: 75 IFCVGRNYHAHAKELSASVFKDNSANPASWPIVFTKVPECVVGPTDDVMLPTGVSEEIDY 134 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E EL +VIG + + A +V GYTI D+ A D + + Q LGK+ DTFCP+G Sbjct: 135 ESELAIVIGTGGRNISRAAAMQHVFGYTIINDVTARDVQMRHQ--QWDLGKSFDTFCPMG 192 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 PWIVT+DE+ + V+ +NG +Q + T I IP +I S +TL PGD+I TG Sbjct: 193 PWIVTADELDGSRT-RVRGWVNGELRQDAQTTDLIFDIPALIETCSRGITLYPGDVIATG 251 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 46 T GVG+ PP++L+ GDV+ EI+ IG E R Sbjct: 252 TAAGVGMGMKPPQYLKAGDVVRIEIDGIGAIENR 285 >UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 233 Score = 164 bits (399), Expect = 2e-39 Identities = 86/198 (43%), Positives = 116/198 (58%) Frame = -3 Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475 V LNY D E P +PF+F K S+V+G D I + V++ V E EL VVIG + Sbjct: 19 VALNYVDSIAEMGFERPTVPFLFPKLSSSVIGDGDPIVVDTTVTRFVDWETELAVVIGTE 78 Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 295 A V ++ A + V GYT+A DI A D Q L GK +DTFCP+G +V + EI + Sbjct: 79 ARNVPAAEALEVVYGYTVANDISARDLLTAD--GQWLRGKGLDTFCPLGHVVVPAAEIPD 136 Query: 294 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115 PQ L V+ +NG Q T + + ++I+ LS TL PGD+ILTGTP G G + +P Sbjct: 137 PQALAVRTWLNGEIVQDGTTADMVFGVGELISYLSRFFTLRPGDVILTGTPAGCGAFMDP 196 Query: 114 PEFLQPGDVITSEIENIG 61 P L+PGDV+ SE+E IG Sbjct: 197 PRGLRPGDVVESEVEGIG 214 >UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Thermococcaceae|Rep: Uncharacterized protein PH0643 - Pyrococcus horikoshii Length = 230 Score = 164 bits (399), Expect = 2e-39 Identities = 94/207 (45%), Positives = 123/207 (59%), Gaps = 2/207 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ + NY +H E PPE P IF K PS ++GP +I L SK V E+EL V+ Sbjct: 22 KIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSIILPRR-SKRVDHEVELAVI 80 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 313 +GK+A V +S AFDY+LGYTI DI A D E KK + K DTF PIGP +V Sbjct: 81 MGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISKGFDTFAPIGPRVVD 140 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 S E+ +P +L + +NG +Q T+Q I KIP++I +S++MTL PGDII TGTP GV Sbjct: 141 SREL-DPSDLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLEPGDIIATGTPPGV 199 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFE 52 G R+ GD I + IE IG E Sbjct: 200 GPLRH-------GDRIEAWIEGIGKME 219 >UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase; n=1; Frankia alni ACN14a|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase - Frankia alni (strain ACN14a) Length = 276 Score = 163 bits (396), Expect = 4e-39 Identities = 83/208 (39%), Positives = 121/208 (58%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+GLNY H +E TPP P +F K+ ++GP D I L V++AV E EL V Sbjct: 69 KIICMGLNYATHLKEMGRTPPTHPTLFAKYTRALIGPTDDI-LVPPVTEAVDWEGELAFV 127 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG D + A + + GYTI D+ DW+ + Q L GK+ + P+GP +VT D Sbjct: 128 IGTTVRFADEAAAREAIAGYTIMNDVTMRDWQF--RTLQFLQGKSFEGSTPLGPALVTPD 185 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ NP +L ++ +NG QKS T+ + +I+ +S +TL PGD++ TGTPGGVG Sbjct: 186 ELDNPADLALRTLVNGEVMQKSRTSDLLFPPVEIVRYVSQFITLEPGDVLTTGTPGGVGH 245 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 RNP +L GDV+T ++E +G V Sbjct: 246 GRNPKVYLADGDVVTVDVEGLGVVRNTV 273 >UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Candidatus Nitrosopumilus maritimus SCM1 Length = 289 Score = 163 bits (395), Expect = 5e-39 Identities = 85/210 (40%), Positives = 120/210 (57%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K++C+ NY DH +EQ LT PE P I K + + G N I+ D + E+EL + Sbjct: 78 NKIICLAFNYVDHAKEQGLTAPEDPAIVIKPRTALNGNNANIECP-DFVTQLDYEVELAL 136 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 +IGK + A + V GY + D+ A D + K Q GK+ D+F P GPWI T+ Sbjct: 137 IIGKNCKNISVEEAQNVVFGYMVFNDVSARDIQFKDK--QFTRGKSFDSFAPCGPWITTA 194 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI PQNL + ING +Q S+T+ KIP+II+++S VMTL GDII TGTP GV Sbjct: 195 DEIQEPQNLKLTTKINGELRQNSSTSNMFIKIPEIISKISKVMTLEKGDIISTGTPAGVM 254 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40 + + FL+ GD + EIE +G ++ Sbjct: 255 LNKPNAIFLKDGDKVEMEIEGLGVLNNTIK 284 >UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaster|Rep: CG11251-PA - Drosophila melanogaster (Fruit fly) Length = 338 Score = 162 bits (394), Expect = 6e-39 Identities = 87/208 (41%), Positives = 122/208 (58%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ V NY D+C+EQ ++ P P KF S++ G D I+ +K + +L VV Sbjct: 133 KIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSS-AKHIDYGCQLAVV 191 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +GK+ +V A ++V G+ + QDI A DW L G +MDTF P+GP IV Sbjct: 192 MGKRCREVSPKEALNHVFGFMVVQDIVARDWNVP------LGGHSMDTFLPLGPTIVHRC 245 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + + NL +K ING ++Q NT I KI +I RLS +TL PGDIILTGTP G G Sbjct: 246 HVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIILTGTPAGSGA 305 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 +R+P FL+PGD+I SEI+N+G +V Sbjct: 306 FRHPSCFLKPGDLIESEIQNLGKMCNKV 333 >UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; n=1; Psychroflexus torquis ATCC 700755|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 162 bits (393), Expect = 8e-39 Identities = 82/179 (45%), Positives = 111/179 (62%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNY H +E + P P +F K S +VGP D I L K+ E+EL ++ Sbjct: 75 KIVCVGLNYAKHAKESGMEVPTEPVLFFKASSAIVGPYDDIILPKKSEKSD-WEVELAII 133 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG KAS V S A D+V GY I DI +++ + Q + GK+ DTF PIGP++VT+D Sbjct: 134 IGDKASYVKESEAMDHVAGYVIHNDISEREYQLERS-GQWVKGKSCDTFAPIGPFMVTTD 192 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 EI +P NL + +NG Q SNT+ I IP +++ +S MTLLPGD+I TGTP GVG Sbjct: 193 EIDDPHNLRLWLKLNGETMQDSNTSDLIFGIPKLVSYISTYMTLLPGDVISTGTPFGVG 251 >UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE; n=41; Bacteria|Rep: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE - Mycobacterium tuberculosis Length = 239 Score = 161 bits (392), Expect = 1e-38 Identities = 89/208 (42%), Positives = 120/208 (57%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+CVG NY DH E PP P IF K + ++GPN I+L + S V E EL +V Sbjct: 36 KVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPANASP-VHFEGELAIV 94 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+ V ++ A D +LGYTI D+ A D +++ Q K DTFCP+GPWIVT Sbjct: 95 IGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSD--GQWTRAKGHDTFCPVGPWIVTDL 152 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 +P +L ++ +NG KQ + T+ IH I I+ +S +MTLLPGD+ILTGTP GVG Sbjct: 153 APFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGVGP 212 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 ++ GD ++ IE IGT V Sbjct: 213 -------IEDGDTVSITIEGIGTLTNPV 233 >UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp. RHA1|Rep: Probable hydrolase - Rhodococcus sp. (strain RHA1) Length = 553 Score = 161 bits (392), Expect = 1e-38 Identities = 85/219 (38%), Positives = 126/219 (57%), Gaps = 12/219 (5%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP------------PELPFIFNKFPSTVVGPNDTIKLKMDVSK 520 V CVG NY +H E + P+ P +F K +TV+ D + D++ Sbjct: 73 VFCVGRNYSEHAAEFAESGFDATGSADGQHVPQYPVVFTKPAATVIACGDPVDPHTDITS 132 Query: 519 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 340 A+ E E+ ++IGK+ASKV A DYV GYT+ D+ A D +++ K Q +GK++DTF Sbjct: 133 ALDYEGEIGIIIGKRASKVSRDDAMDYVWGYTLINDVTARDLQRDHK--QWFIGKSLDTF 190 Query: 339 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 160 CP+GPW VT+DEI + +L ++ +NG +Q +NT Q I +P II LS +TL PGD+ Sbjct: 191 CPLGPWAVTADEI-DINDLQLQTRVNGELRQDTNTAQLIFDVPTIIETLSAGITLEPGDV 249 Query: 159 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 I TGTP GVG+ +PP++L GD + +G + Sbjct: 250 IATGTPVGVGIGFDPPKYLVEGDEVIVSAPGLGELRNTI 288 >UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 286 Score = 161 bits (392), Expect = 1e-38 Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 2/210 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 +LCVGLNY+ H EE L PE P IF K + GP + + + D + E ELT+VI Sbjct: 70 ILCVGLNYRRHAEECNLQIPENPAIFMKPSDALAGPLEDVPIHKDCQSMLDYEGELTIVI 129 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVTS 310 GK V +++ DYVLGYT+ D+ A +++ +S Q K+ D FCPIGP I ++ Sbjct: 130 GKDCKNVSAANFQDYVLGYTVGNDVSARNYQLPANVSGGQFGYAKSFDKFCPIGPCIAST 189 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 I +PQ L +NG ++Q++ T+ I+ I +I LS TL G ILTGTP GVG Sbjct: 190 KVIPDPQKLTYWTKVNGEKRQETGTDDMIYTIGQVIEHLSRGTTLRAGTAILTGTPSGVG 249 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40 ++ P FL+ GD + ++ IG+ +++ Sbjct: 250 LFMEPKNFLKDGDEVEIYVDGIGSIINKMK 279 >UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family protein; n=5; Pezizomycotina|Rep: Fumarylacetoacetate hydrolase family protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 289 Score = 161 bits (392), Expect = 1e-38 Identities = 82/209 (39%), Positives = 117/209 (55%), Gaps = 2/209 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM--DVSKAVVCEIELTV 490 V C+GLNY+ H E L P+ P +F K +++ GP D I + + + E EL + Sbjct: 72 VRCLGLNYEQHARESNLPIPKYPVLFYKPVTSIAGPRDDIPISTMAQEGEGLDYECELVI 131 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK+A V S A DYVLGY + D+ DW+ + Q LGK D + P GP IV+S Sbjct: 132 VIGKEAKDVPESRALDYVLGYAVGNDVSHRDWQIKRGGGQWGLGKGFDGWAPFGPGIVSS 191 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 I +P L++ +NG Q S+T I + ++A LS TLLPGD+I TGTP GVG Sbjct: 192 RLIRDPNALHISTRLNGQVVQSSSTKDMIFSVAKVVAFLSQGTTLLPGDLIFTGTPQGVG 251 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 + R P +L+ GD + +E +G+ +V Sbjct: 252 MGRKPALWLKDGDQVEVSLEGVGSCVNQV 280 >UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: Bll6360 protein - Bradyrhizobium japonicum Length = 314 Score = 161 bits (391), Expect = 1e-38 Identities = 82/209 (39%), Positives = 121/209 (57%), Gaps = 1/209 (0%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V G K + +GLNY DH E L P P +F K +++ GPND + L K E+ Sbjct: 93 VSGVGKFVAIGLNYADHAAEAGLPLPSEPIVFQKAITSLSGPNDAVVLPRGSLKGD-WEV 151 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL +VIG +AS V+ A YV GY + D+ +++ + GK DTF P+GPW Sbjct: 152 ELGIVIGSRASYVEPVEALQYVAGYCVVNDVSEREYQMERG-GTWDKGKGCDTFGPVGPW 210 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 +VT+DE+ +P L++ +NG + Q+ NT + I++ +S MTL+PGDII TGTP Sbjct: 211 LVTTDEVPDPGRLDIWLELNGRRMQQGNTRTMVFGCAGIVSYVSQFMTLMPGDIIATGTP 270 Query: 141 GGVGVYRNP-PEFLQPGDVITSEIENIGT 58 GVG+ P P +L+ GD++T I+ +GT Sbjct: 271 PGVGMGMKPDPIYLKVGDIMTLGIQGLGT 299 >UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase; n=2; Rhodococcus|Rep: Possible fumarylacetoacetate hydrolase - Rhodococcus sp. (strain RHA1) Length = 296 Score = 161 bits (391), Expect = 1e-38 Identities = 79/203 (38%), Positives = 116/203 (57%), Gaps = 1/203 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 ++ +G+NY DH EE LT P+ PF+F KFP+++ GP DTI+ V E+EL V Sbjct: 72 QIFAIGVNYADHVEESGLTLPDAPFVFTKFPASITGPYDTIE---HPGGLVDFEVELVAV 128 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFCPIGPWIVTS 310 IGK+A V + ++YV G T+ QD+ D + Q LGK+ F PIGP +VT Sbjct: 129 IGKEARHVPVAEGWEYVAGLTLGQDLSERDLQLSGPPPQQFTLGKSFAGFAPIGPVLVTP 188 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DE +P ++ V ++G Q S T I IP +++ LS+++ L PGD+I TGTP G+G Sbjct: 189 DEFADPDDIEVSTILSGELMQNSRTRHLIFPIPVLVSYLSSILPLRPGDLIFTGTPSGIG 248 Query: 129 VYRNPPEFLQPGDVITSEIENIG 61 R+P + D + S + IG Sbjct: 249 FTRDPKRLIGVDDELVSRADTIG 271 >UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase; n=8; Pezizomycotina|Rep: Predicted fumarylacetoacetate hydralase - Aspergillus oryzae Length = 289 Score = 161 bits (391), Expect = 1e-38 Identities = 84/210 (40%), Positives = 116/210 (55%), Gaps = 3/210 (1%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI---KLKMDVSKAVVCEIELT 493 V C+GLNY+ H E L P+ P +F K + + GP D I + DV + + E EL Sbjct: 72 VRCLGLNYEQHARESNLPIPKYPVLFYKPITAITGPYDDIPICSMAQDV-EGLDYECELV 130 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 +VIGK+A + A DYVLGY + DI DW+ + Q LGK D + P GP IV+ Sbjct: 131 LVIGKQAKNIPEEQALDYVLGYAVGNDISHRDWQLKRGGGQWGLGKGFDGWAPFGPGIVS 190 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + I NP LN+ +NG Q S+T I + ++ LS TLLPGD+I TGTP GV Sbjct: 191 TKLIRNPNALNISTKVNGQTVQSSSTKDMIFGVAQTVSFLSQGTTLLPGDLIFTGTPQGV 250 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G+ R P +L GD + +E++G+ RV Sbjct: 251 GMGRKPAAWLTNGDQVEVSLEDVGSCVNRV 280 >UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiales|Rep: Putative hydrolase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 304 Score = 160 bits (389), Expect = 3e-38 Identities = 84/214 (39%), Positives = 120/214 (56%), Gaps = 7/214 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP-------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505 V CVG NY++H E L PE F K P+ V+G +K ++ ++ E Sbjct: 91 VFCVGRNYREHIIEGNLARGRPANSFPEAIEFFTKAPTAVIGHGGHVKRHAGLTDSLDYE 150 Query: 504 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 325 +EL +VIG+ + + A D+V GYTI DI A D + Q GK++DT CP+GP Sbjct: 151 VELAIVIGRAGADIPREKALDHVFGYTIVNDITARDLQARH--GQWFKGKSLDTSCPMGP 208 Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 +V I + NL V S+NG +Q+ NT+ I + ++A+LS MTLLPGD+I TGT Sbjct: 209 VVVHRSAIPDANNLAVSLSVNGELRQQDNTSDMIFDVAAVVAQLSAGMTLLPGDVIATGT 268 Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 P GVG PP LQ GDV+++ +E+IGT + Sbjct: 269 PKGVGFALTPPRCLQVGDVVSASVEHIGTLTNEI 302 >UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium difficile|Rep: Putative hydrolase - Clostridium difficile (strain 630) Length = 294 Score = 160 bits (388), Expect = 3e-38 Identities = 83/214 (38%), Positives = 122/214 (57%), Gaps = 6/214 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 ++C+GLNYKDH E + + P+ P F+K ++G +D I L D+ + + E Sbjct: 83 IICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYES 142 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL V+IGK+ + A++Y+ GYTI DI ++ K Q GK++DT +GP Sbjct: 143 ELAVIIGKEGINISKEDAYEYIFGYTIVNDI--SERALQDKHVQWFRGKSLDTHTSMGPC 200 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 IV +E +P L++ +NG +Q SNT FI IP II LS MTL PGDII TGTP Sbjct: 201 IVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTP 260 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 GV + NP +L+ GD++ ++E IG + V+ Sbjct: 261 AGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD 294 >UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 274 Score = 158 bits (384), Expect = 1e-37 Identities = 81/204 (39%), Positives = 121/204 (59%), Gaps = 2/204 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVV 487 V C+GLNYK+H E K+T P+ P +F K + + + I L V E+EL ++ Sbjct: 65 VRCIGLNYKEHAAEMKMTLPDAPTVFLKANTCISSAAEPIVLPSVVDHDEADYEVELAII 124 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++ V + A YVLGY++A D+ A + K SQ K MD FCP+GP IV+++ Sbjct: 125 IGQRCKNVSVAEAMGYVLGYSVANDVTAR--KHQGKTSQWSYAKGMDGFCPLGPCIVSAE 182 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 +I +P ++ S+NG Q ++ + I I ++++ LS TLLPG +I+TGTP G+GV Sbjct: 183 KIPDPSVFQLRTSLNGKTMQNASADDMIFSIAEVVSYLSQGHTLLPGTVIITGTPCGIGV 242 Query: 126 YRNPPEFLQPGDVI-TSEIENIGT 58 +NPP FL+PGD + S IGT Sbjct: 243 SQNPPVFLKPGDRLRISASHGIGT 266 >UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; Bordetella|Rep: Putative uncharacterized protein - Bordetella parapertussis Length = 294 Score = 157 bits (382), Expect = 2e-37 Identities = 85/217 (39%), Positives = 118/217 (54%), Gaps = 10/217 (4%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP----------PELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 514 V CVG NY +H E + P P IF+K PS+V GP D I +D +V Sbjct: 79 VFCVGKNYHEHAREFARSGFDSSAAAGAVPAAPIIFSKPPSSVSGPGDAIDTALDPCDSV 138 Query: 513 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 334 E EL VVIGK + +V GYT+ D+ T K+ SQ LLGK +D +CP Sbjct: 139 DYEAELAVVIGKAGRVAPDDDPWSFVFGYTLVNDV--TSRGLQKRHSQWLLGKGIDGYCP 196 Query: 333 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 154 +GP +V++DEIG+ L + C +NG +Q + + I IP ++ + +TL PGD+I Sbjct: 197 MGPALVSADEIGDIGALEITCEVNGELRQSARLSDLIFDIPTLVRAIGASITLQPGDVIA 256 Query: 153 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TGTP GVG+ PP++L+ GDV+ E IG E V Sbjct: 257 TGTPVGVGIGFTPPKYLRRGDVVRVRAEPIGVLENPV 293 >UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Symbiobacterium thermophilum|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Symbiobacterium thermophilum Length = 254 Score = 157 bits (381), Expect = 2e-37 Identities = 84/208 (40%), Positives = 117/208 (56%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+G NY+DH E PE P F K PS ++GP + I+L D V E EL VV Sbjct: 56 KIVCIGRNYRDHAAELGNAAPERPMFFLKAPSALIGPGEAIRLP-DPDATVHWEAELAVV 114 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++ V + A YV GYTIA D+ D +K GK+ DTFCP GP +VT Sbjct: 115 IGRRMKDVAPADALSYVFGYTIANDVSHRDAQKADGAFGFGRGKSYDTFCPCGPAVVT-- 172 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E +P + + + N +Q +T IH +P++++ LS +MTL+PGD++LTGTP GVG Sbjct: 173 EGIDPADALITLTCNEEVRQSDSTGLMIHPVPELLSYLSQIMTLMPGDLVLTGTPKGVGA 232 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 ++PGD+I I IGT V Sbjct: 233 -------MKPGDLIEIHIPGIGTLANPV 253 >UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=5; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Nocardioides sp. (strain BAA-499 / JS614) Length = 284 Score = 157 bits (380), Expect = 3e-37 Identities = 76/203 (37%), Positives = 118/203 (58%), Gaps = 1/203 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKL-TPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 + + +GLNY++H E P +LP +F KF S++ GP + L E+E+ Sbjct: 77 QAIAIGLNYEEHAHETGYQVPTQLPPVFAKFASSITGPRGLVDLPP--GGHTDWEVEVVA 134 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIG+ A ++ A+ +V G T+ QD+ + Q L K+ F P+GPW+VT Sbjct: 135 VIGRTAHRISPDEAWGHVAGLTVGQDLSERISQMAGPAPQFGLAKSFPGFSPMGPWLVTP 194 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 +E+ +P +L + C+I+G Q T++ I IP IA LS V+TLLPGD++ TGTP GVG Sbjct: 195 EELADPDDLALGCAIDGETVQDGRTSKLIFSIPRSIAALSQVLTLLPGDVVFTGTPDGVG 254 Query: 129 VYRNPPEFLQPGDVITSEIENIG 61 + R+P FL+PG+ + + +E IG Sbjct: 255 LGRSPQRFLRPGETLRTWVEGIG 277 >UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Clostridiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase - Alkaliphilus metalliredigens QYMF Length = 300 Score = 156 bits (378), Expect = 5e-37 Identities = 80/214 (37%), Positives = 124/214 (57%), Gaps = 6/214 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKL---TPPELPF---IFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V+CVGLNY +H +E K E+P F+K + V GP + I+ +++++ E+ Sbjct: 89 VICVGLNYAEHIDETKKGFDENMEIPLHTVYFSKRANQVKGPGEEIESHSHLNESMDYEV 148 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL V+IGK+ + A +Y+ GYTI D+ A +KN Q GK++D F +GP Sbjct: 149 ELAVIIGKEGINISKEEAKEYIFGYTILNDLSARGLQKNHV--QWFRGKSLDGFTSMGPC 206 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 IV +G P L++K +N +Q SNT + + II+ +S MTLLPGD+I TGTP Sbjct: 207 IVHGSSVGFPLELDIKSRVNDELRQNSNTKFMMKDVSTIISEISQGMTLLPGDVIATGTP 266 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 GVG+ PP FL+ GD + EI+++G + +++ Sbjct: 267 SGVGMGFTPPRFLKAGDTVECEIQHMGLLKNKIK 300 >UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=3; Alphaproteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Roseobacter sp. MED193 Length = 285 Score = 156 bits (378), Expect = 5e-37 Identities = 77/201 (38%), Positives = 108/201 (53%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 + CVGLNY DH E L PE P +FNK T GPND I +SK + E+EL +VI Sbjct: 75 IWCVGLNYSDHAAEAGLPVPEEPILFNKSTVTYCGPNDDILKSAQMSK-LDWEVELGIVI 133 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304 K A + A D++ G+ + DI W+ + Q + GK+ FCP GP + T +E Sbjct: 134 SKPALNISRDQAMDHIAGFVLVNDISERAWQMERS-GQWVKGKSFPNFCPTGPVLATKEE 192 Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124 + QNL + +NG + Q NT I + I++ +S L PGD+I TGTP GVG Sbjct: 193 FADVQNLGMWLDVNGERMQTGNTGTMIFDVATIVSYMSEFTRLEPGDLICTGTPPGVGAG 252 Query: 123 RNPPEFLQPGDVITSEIENIG 61 PP +L GD ++ I+ +G Sbjct: 253 MTPPVWLNEGDKVSLGIDGLG 273 >UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Exiguobacterium sibiricum 255-15|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Exiguobacterium sibiricum 255-15 Length = 277 Score = 155 bits (377), Expect = 7e-37 Identities = 80/210 (38%), Positives = 117/210 (55%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 V+CVG NY DH +E +F K PS++VGP + I+ D+++ + E EL ++I Sbjct: 70 VICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFEAIERHADLTQQLDYEGELAIII 129 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304 G + +A D+V GY+I D+ A D +K Q GK++D FCP GP IVT D Sbjct: 130 GTSGRDLTPENALDHVFGYSIVNDVTARDLQKEHV--QFFRGKSLDGFCPFGPVIVTEDS 187 Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124 +P ++ V+ +NG +Q +T + + I+ +S MTL GDII TGTP GVG Sbjct: 188 F-DPTDVLVETRVNGQLRQSGSTKLMLRDVVTILTEVSRGMTLEAGDIIATGTPAGVGHG 246 Query: 123 RNPPEFLQPGDVITSEIENIGTFETRVEEF 34 PP +LQ GDV+ IE IG + V+ + Sbjct: 247 MKPPTYLQDGDVVDISIEGIGHLQNHVKAY 276 >UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=2; Proteobacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Fulvimarina pelagi HTCC2506 Length = 337 Score = 155 bits (376), Expect = 9e-37 Identities = 73/200 (36%), Positives = 118/200 (59%) Frame = -3 Query: 660 LCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIG 481 + +GLNY DH E P P +F+K PS++ GP+D + + +K + E+EL VVIG Sbjct: 128 IAIGLNYADHAAETGADLPVEPLVFSKAPSSICGPHDELPIPPGSTK-LDWEVELAVVIG 186 Query: 480 KKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI 301 ++A ++ + A ++V G+ + D+ ++K + Q + GK+ +GPW+VT D + Sbjct: 187 ERAYNINETEAMNHVAGFCLCNDVSERAFQKERG-GQFIKGKSSPRTGALGPWLVTPDRL 245 Query: 300 GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYR 121 G+PQ L++ S+NG +Q+ T + I++ LS M L PGD+I TGTP GVG Sbjct: 246 GDPQQLDLWLSVNGEIRQRGTTRDMLFSAAFIVSYLSKFMILEPGDVITTGTPSGVGAGM 305 Query: 120 NPPEFLQPGDVITSEIENIG 61 PP+FL+ GD++T I +G Sbjct: 306 TPPQFLREGDILTLGIGGLG 325 >UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farcinica|Rep: Putative hydrolase - Nocardia farcinica Length = 285 Score = 155 bits (375), Expect = 1e-36 Identities = 80/209 (38%), Positives = 116/209 (55%), Gaps = 1/209 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTV 490 K++C G NY+ H E PE P +F KF T+ + I L M + A + E EL V Sbjct: 62 KIVCCGHNYRAHIAELGRAEPEFPTLFAKFADTLTAWDADITLGMAAADAGLDWEAELAV 121 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 V+G + + D + A + GYT+A D W++ + +Q L GKA D P+GP +VT Sbjct: 122 VVGAELRRADRATARAGIAGYTVANDFSVRTWQR--RTAQWLQGKAFDATTPLGPDLVTP 179 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DE L + C +NGV +Q +T+ + +++ +S TL PGD++LTGTPGGVG Sbjct: 180 DEADPGDGLRITCRVNGVVEQCGSTDDLLFDPAALLSYISAFTTLRPGDVVLTGTPGGVG 239 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 V +PP L GDV+ +EIE IG R+ Sbjct: 240 VAADPPRHLGDGDVVETEIEGIGLLRNRI 268 >UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Xanthobacter sp. (strain Py2) Length = 281 Score = 154 bits (374), Expect = 2e-36 Identities = 76/209 (36%), Positives = 114/209 (54%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 DK++CVGLNY DH E T P +F ++ + VG + ++ S E EL V Sbjct: 71 DKIVCVGLNYHDHVNETGRTVTPNPMLFARYAGSQVGAGTALVKPLE-SDEFDYEGELAV 129 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 +IGK ++ + A +V GY D DW+++ SQ + GK GPW+V++ Sbjct: 130 IIGKAGRRISEADALSHVAGYACYNDASVRDWQRHT--SQFMPGKTFAATGAFGPWMVSA 187 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI +P L + +NG Q Q ++ + I IP +IA S ++ LLPGD+I++GTPGGVG Sbjct: 188 DEIPDPTRLTLATRLNGAQVQHTSVDLMITPIPTLIAYTSTILPLLPGDVIVSGTPGGVG 247 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 R P F++ GDV+ E+ IG + Sbjct: 248 ARRTPKLFMKDGDVVEVEVSGIGVLRNPI 276 >UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=7; cellular organisms|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Methanococcus maripaludis Length = 202 Score = 153 bits (372), Expect = 3e-36 Identities = 86/209 (41%), Positives = 121/209 (57%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C GLNYKDH EE K+ P+ P IF K S+++ + IK+ S+ V E EL +V Sbjct: 7 KIVCAGLNYKDHAEELKMKLPKEPVIFLKPTSSIIYNEEAIKIPK-ASERVDYEAELAIV 65 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK V +Y+ G+TI D+ A D ++ K Q K+ DTF PIGP IV+ Sbjct: 66 IGKTCKSVKKEDVKNYIKGFTILNDVTARDLQE--KDGQWTRAKSFDTFSPIGPKIVSGI 123 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + N L ++ +NG KQ SNTN I + +++ +S++MTL PGDII TGTP G+G Sbjct: 124 DANN---LKIQLRVNGKIKQDSNTNNMIFSVEELVEFVSSIMTLYPGDIISTGTPPGIGK 180 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 L+ GD++ EIENIG + VE Sbjct: 181 -------LEKGDIVEIEIENIGILKNFVE 202 >UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG11179.1 - Gibberella zeae PH-1 Length = 281 Score = 153 bits (371), Expect = 4e-36 Identities = 83/213 (38%), Positives = 118/213 (55%), Gaps = 6/213 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA--VVCEIELTV 490 V+C+GLNY DH EE ++ P++P +F K + + GP+D + L + + E EL + Sbjct: 66 VVCIGLNYTDHAEEAQMPIPKVPVVFFKPVTALAGPHDDLVLPHTSWEKGRLDYESELVI 125 Query: 489 VIGKKASKVDSSHAFDYVLGYTI--AQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPW 322 VIGKKAS+V A DYV YT DI W+ + ++ Q K D PIGP Sbjct: 126 VIGKKASRVSKDDALDYVFSYTFHAGNDISNRAWQLDPQLGGGQWCYSKCFDCSAPIGPA 185 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 IV+ D +G+ L ++ ++N Q Q NTN I + +I++ LS MTLLPG I TGTP Sbjct: 186 IVSKDILGSAVGLGIRGTLNDTQSQDGNTNNMIFGVAEIVSFLSQGMTLLPGTFIFTGTP 245 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GVG + P ++ GDV EI+ IG +V Sbjct: 246 AGVGFGKKPQISVKEGDVTQVEIDGIGAIVNKV 278 >UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Methylobacterium sp. 4-46|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Methylobacterium sp. 4-46 Length = 480 Score = 152 bits (369), Expect = 7e-36 Identities = 78/213 (36%), Positives = 118/213 (55%), Gaps = 4/213 (1%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K++ +G NY+ H E P+ P +FNK+ + + TIKL V++ E+EL + Sbjct: 269 EKIIMMGFNYRHHAAETGTPIPKDPPLFNKYNNALNHHGGTIKLPTAVAREFDYEVELVI 328 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 V G++ S V + A D V GY D A D + SQ ++GK D F P+GP++VTS Sbjct: 329 VFGRECSNVSEAEALDCVAGYATGNDFSARDLQT--LTSQFMIGKTADGFAPLGPYLVTS 386 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 D + +P NL ++ +NGVQ+Q NTN I +I+ S +MT+ PGDI TGTP GV Sbjct: 387 DLVKDPNNLRLETRVNGVQRQDWNTNDMIFNCRQLISFASKMMTIKPGDIFYTGTPHGVI 446 Query: 129 VYRNPP----EFLQPGDVITSEIENIGTFETRV 43 P ++L+PGD + +E +G R+ Sbjct: 447 FGEKKPRAERQWLKPGDEVACSLEGLGELRFRL 479 >UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 282 Score = 152 bits (368), Expect = 9e-36 Identities = 84/203 (41%), Positives = 112/203 (55%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 DKVLCV N+++ E K PE P +F +F ++ G + K D S+A E EL V Sbjct: 71 DKVLCVATNFREPAREGK-PEPEYPLVFTRFANSFTGHGQPLA-KPDRSEAYDFEGELAV 128 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK ++ +S A +V GY D DW+K+ +Q GK GPWIVT+ Sbjct: 129 VIGKGGHRIPASEAMAHVGGYCCLNDGSVRDWQKHS--TQFTPGKNFHRSGSFGPWIVTA 186 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI +P L ++ +NGV KQ+ ++ I IP +IA S L+PGD+I TGTP G G Sbjct: 187 DEIPDPTVLTLQTRVNGVVKQRIGIDRMIFDIPWLIAYFSTFTPLVPGDVIATGTPSGFG 246 Query: 129 VYRNPPEFLQPGDVITSEIENIG 61 R PPE+L GD I EI IG Sbjct: 247 SSRTPPEYLSIGDAIEVEISEIG 269 >UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Bacillus halodurans|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus halodurans Length = 276 Score = 151 bits (367), Expect = 1e-35 Identities = 86/210 (40%), Positives = 125/210 (59%), Gaps = 2/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKL--TPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 K++ +NY H +E + T L F F K ++++GPND I L + ++ + E+EL Sbjct: 75 KIVAAPVNYMSHKKEMNVDHTARVLGF-FLKATTSIIGPNDPIILPYN-NRRIDHELELA 132 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 VIGK+A V +A DY+ GYT D+ KN++ + L K+ DTF PIGPWIVT Sbjct: 133 FVIGKRAKHVKKENAHDYIFGYTGLNDVTVRP-TKNRE-EERCLRKSFDTFTPIGPWIVT 190 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 SDEI +PQNL + +N +Q NTNQ + I +++ S+VMTL PGD+I TGTP GV Sbjct: 191 SDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTLEPGDLIATGTPDGV 250 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G ++ GD +T ++E+IG+F V Sbjct: 251 GP-------IKDGDTVTLQMESIGSFSNPV 273 >UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Desulfitobacterium hafniense|Rep: Fumarylacetoacetate (FAA) hydrolase - Desulfitobacterium hafniense (strain DCB-2) Length = 251 Score = 151 bits (366), Expect = 2e-35 Identities = 85/208 (40%), Positives = 118/208 (56%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+GLNY H EE + P IF K +++VGP D I L +S+ V E EL VV Sbjct: 56 KIVCIGLNYAKHIEELGHDFHDDPVIFLKPVTSLVGPEDEIILPA-MSQQVDYEAELVVV 114 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK A + A DY+ G+T D+ A D +K K Q K DTFCPIGPWIV Sbjct: 115 IGKTAKDLAEDQAEDYIFGFTCGNDVTARDLQK--KDGQWTRSKGFDTFCPIGPWIVRDL 172 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + +N+ ++ +NG KQ S T+ IH +P +++ +S +MTL PGD+I+TGTP GVG Sbjct: 173 DY---RNVKIRSVLNGEVKQSSQTSHLIHSVPKLVSYISKIMTLNPGDLIMTGTPEGVGP 229 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 ++ GD I +I+ IG V Sbjct: 230 -------MKTGDAIAIDIKGIGRLHNLV 250 >UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=4; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Delftia acidovorans SPH-1 Length = 309 Score = 151 bits (365), Expect = 2e-35 Identities = 75/208 (36%), Positives = 113/208 (54%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNYK H E + E P +F +F ++ D + L+ S+ E EL V Sbjct: 98 KLICVGLNYKTHVAETRRADSEHPSLFLRFNDSLAADGDEL-LRPAFSERFDWEGELAFV 156 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+ + AFD++ GY D+ DW+++ Q GK P GPW+VT D Sbjct: 157 IGRGGRHIAKEDAFDHIAGYACFNDVSVRDWQRHTH--QFTPGKNFPGTAPFGPWLVTRD 214 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ + ++L ++ +NG Q+++ I IP I+A +S L PGD+I TGTPGGVG Sbjct: 215 EVADVRSLALQTRLNGSVMQQASLGDLIFDIPTIVAYVSRFTPLSPGDVIATGTPGGVGD 274 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 R PP +++ GDV+ EI +G R+ Sbjct: 275 RREPPLYMKHGDVVEVEITGLGVLRNRI 302 >UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase; n=1; Lactobacillus plantarum|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase - Lactobacillus plantarum Length = 276 Score = 150 bits (364), Expect = 3e-35 Identities = 73/209 (34%), Positives = 116/209 (55%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 ++ VG+NY+DH E +T P++P IF KF S++ N T+ E EL V+ Sbjct: 71 QIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATH---GPETDWETELVVM 127 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK + ++ A +V G + +D+ + Q +GK+ + + P+GPW+ T D Sbjct: 128 IGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAPVGPWLTTVD 187 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ N + + ++NG Q++ +Q I K+PD++ LS V L PGD+I TGTP G GV Sbjct: 188 ELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIFTGTPSGTGV 247 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 RNP FLQ GD + +I ++GT ++ Sbjct: 248 GRNPQVFLQAGDQLCGQITHLGTLNITIK 276 >UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep: Putative oxygenase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 287 Score = 150 bits (363), Expect = 4e-35 Identities = 75/211 (35%), Positives = 112/211 (53%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 DK+LC+GLNY+ H EE + P P F +F ++ + L+ S E EL V Sbjct: 77 DKILCIGLNYRLHAEEAGMAIPARPSTFVRFAGSLAAQGQPV-LRPAESDQFDYEAELAV 135 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 +IGK A +V + A ++V GY + DW+++ +Q GK GPW+VT+ Sbjct: 136 IIGKPARRVSQARAMEHVAGYACLAENSVRDWQRHS--TQATPGKNFVRSGAFGPWLVTA 193 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DE G P+ + V +NG Q + I + +++ LS LLPGD+I TGTP GVG Sbjct: 194 DEAGAPEAMTVIGRLNGETVQHDSVANMIFTVAQLVSYLSTFAELLPGDVIATGTPAGVG 253 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 + R PP +L+PGDV +I +G V++ Sbjct: 254 MSRKPPRYLRPGDVFEVDISGVGVLRNPVDD 284 >UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=6; Enterobacteriaceae|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Enterobacter sp. 638 Length = 287 Score = 150 bits (363), Expect = 4e-35 Identities = 82/211 (38%), Positives = 114/211 (54%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K+LCVG+NY + +E P P +F +FP + G N + LK S E EL V Sbjct: 73 EKILCVGMNYAEKRQEFDQHNPA-PTLFVRFPDSQTGHNSPV-LKPRHSSEFDYEGELAV 130 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 +IGK + A +V GY+ D A DW+ + GK GPW+ T+ Sbjct: 131 IIGKGGENISRDDALRHVAGYSCYMDGSARDWQH----TWFTAGKNWRQTGAFGPWMATA 186 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI +P L ++ +NG Q+ NT+ IHK+ ++I +S L PGD+I+TG+PGGVG Sbjct: 187 DEIPDPHRLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLSPGDVIITGSPGGVG 246 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 RNPP F+Q GD I EIENIG + E Sbjct: 247 KKRNPPLFMQEGDRIEVEIENIGHLSNVIME 277 >UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase; n=1; Thermoplasma acidophilum|Rep: Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase - Thermoplasma acidophilum Length = 315 Score = 149 bits (362), Expect = 5e-35 Identities = 85/210 (40%), Positives = 120/210 (57%), Gaps = 2/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+LC+G+NY +H +E + E P IF KF +++G D I + D +K + E EL V+ Sbjct: 113 KILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGNMDDITVPKD-AKQIDYEGELVVI 171 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+ + +SS + GYTI D+ A D + + SQ LLGKA+ TF PIGP IV + Sbjct: 172 IGRSSGTAESS-----IFGYTIGNDVSARDLQF--RTSQWLLGKALPTFAPIGPVIVGKN 224 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV-- 133 E+G ++L + +NG +Q NT+ I + I+ LS L PGDII TGTP GV Sbjct: 225 ELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDYLSGYFNLGPGDIIFTGTPEGVIL 284 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G+ N +L+ GDVI I IGT R+ Sbjct: 285 GLPENERVWLKHGDVIDVSITGIGTLTNRI 314 >UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase; n=1; Cenarchaeum symbiosum|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase - Cenarchaeum symbiosum Length = 288 Score = 149 bits (362), Expect = 5e-35 Identities = 79/208 (37%), Positives = 116/208 (55%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+ C+ NY DH ++Q +PP+ P I K + + G D I + V K + E+EL ++ Sbjct: 79 KIFCLAFNYADHAQDQDRSPPDEPVIVMKPRTALCGNGDDIVMPPFV-KELDYEVELALI 137 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK+ VD A + + GYTI D+ A D + Q K +DTF P GPWI ++D Sbjct: 138 IGKRCRDVDVIGAKEAIFGYTILNDVSARDIQFRD--GQFTRAKGLDTFAPCGPWITSAD 195 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +P L + +NG +Q S+T++ K +I+++LS+ MTL GDII TGTP GV + Sbjct: 196 EVQDPGRLKMTTKVNGRARQDSSTSKMHIKPFEIVSKLSSSMTLEKGDIISTGTPSGVAL 255 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 E+L GD I EIE +G V Sbjct: 256 NNPDSEYLAAGDEIEMEIEGLGVLRNTV 283 >UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; cellular organisms|Rep: Uncharacterized protein AF_2225 - Archaeoglobus fulgidus Length = 250 Score = 148 bits (358), Expect = 1e-34 Identities = 85/202 (42%), Positives = 118/202 (58%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ VGLNY DH EE + PE P +F K + V+G +D I L +S+ V E EL VV Sbjct: 45 KIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCIILPQ-ISQRVDYEGELAVV 103 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 I + V ++A DY+LGYT D+ A D + K Q K+ DTF P+GP+I Sbjct: 104 IAEDCRNVPETNAADYILGYTCFNDVTARDLQA--KDGQWTRAKSFDTFAPLGPYIA--- 158 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI +P L ++ +NG QKSNT+ I + +++ +S+VMTL GD+I TGTP GVG+ Sbjct: 159 EIDDPSKLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTLKAGDVIATGTPAGVGM 218 Query: 126 YRNPPEFLQPGDVITSEIENIG 61 L+ GDV+ EIE IG Sbjct: 219 -------LKDGDVVEVEIEKIG 233 >UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; n=1; Citrobacter koseri ATCC BAA-895|Rep: hypothetical protein CKO_03358 - Citrobacter koseri ATCC BAA-895 Length = 295 Score = 147 bits (357), Expect = 2e-34 Identities = 82/211 (38%), Positives = 114/211 (54%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K+LCVG+NY + +E P P +F +F + G N + LK S E EL V Sbjct: 81 EKILCVGMNYAEKRQEFDQHDPA-PTLFVRFADSQTGHNMPV-LKPRHSHEFDYEGELAV 138 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 +IG + HA D+V GY+ D A DW+ S GK GPW+VT+ Sbjct: 139 IIGNGGENISRDHALDHVAGYSCYMDGSARDWQH----SWFTAGKNWRQTGAFGPWMVTA 194 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI +P L ++ +NG Q+ NT+ IHK+ ++I +S L GD+I+TG+PGGVG Sbjct: 195 DEIPDPHQLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLNSGDVIITGSPGGVG 254 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 RNPP F+Q GD I EIE+IG + E Sbjct: 255 KKRNPPLFMQEGDRIEVEIEHIGHLSNVIME 285 >UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lmo2266 protein - Listeria monocytogenes Length = 282 Score = 147 bits (356), Expect = 3e-34 Identities = 79/213 (37%), Positives = 121/213 (56%), Gaps = 2/213 (0%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496 + ++ +G NY +H E K PE +F K ++++ N I+L +++ + E EL Sbjct: 72 NNIIAIGKNYYNHVLEMGSKEDVPEHILVFTKSANSLLPHNGNIELHQNITGQLDYEGEL 131 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 V+IG+K + A + G+TI DI A D +K K Q LGK++D CPIGP+++ Sbjct: 132 AVIIGEKVRDISEQEALSAIFGFTILNDITARDLQKKHK--QFYLGKSLDASCPIGPFVL 189 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 ++ P +++ +NG +Q +T++FI + II+ LS TLLPGDII TGTP G Sbjct: 190 ENNANKEPV-FHIETKVNGEVRQSDSTDKFIFGLARIISDLSKGHTLLPGDIIATGTPSG 248 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 VG PP FLQ GD+I I+ IGT +V + Sbjct: 249 VGNGMTPPTFLQDGDIIEITIDKIGTLTNKVRK 281 >UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Oceanicola batsensis HTCC2597|Rep: Fumarylacetoacetate hydrolase family protein - Oceanicola batsensis HTCC2597 Length = 252 Score = 147 bits (355), Expect = 3e-34 Identities = 85/208 (40%), Positives = 115/208 (55%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNYK H EE PE P +F PS V+ TI L ++ + E E+ +V Sbjct: 55 KLVCVGLNYKRHAEESGAAIPEEPMLFMCAPSAVIPDGGTILLDSQDAR-IDYEAEIAIV 113 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK+A + + A + GYTI D+ D++K K Q K+ DT+ P+GPWI T Sbjct: 114 IGKQARNLPEADARSCIFGYTICNDVSNRDYQK--KDGQFTRAKSFDTYKPLGPWIETGL 171 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + P N + NG +Q+SNT+ I I I+A +S +MTL PGD+I+TGTP GVG Sbjct: 172 D---PDNAAISLRQNGELRQQSNTSDMIFSIDRIVAFVSGIMTLNPGDVIITGTPEGVGP 228 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 R+ GD I EIE IGT V Sbjct: 229 MRS-------GDRIEIEIEGIGTLANSV 249 >UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Clostridium beijerinckii NCIMB 8052 Length = 294 Score = 146 bits (354), Expect = 4e-34 Identities = 84/218 (38%), Positives = 116/218 (53%), Gaps = 7/218 (3%) Frame = -3 Query: 672 NDKVLCVGLNYKDHCEEQKLTPPEL-----PFI--FNKFPSTVVGPNDTIKLKMDVSKAV 514 N ++C+G+NY +H E E P+ F+K +T D I + ++ Sbjct: 79 NQDIICLGINYMEHAVESARYKNEAFGGDRPYAVYFSKRVNTATADGDYIPSYPQIVDSL 138 Query: 513 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 334 E EL V+IGK A V AFDYV GYTI D+ A + + K Q GK++D F P Sbjct: 139 DYEAELAVIIGKDAKDVPKEKAFDYVFGYTIINDVSARNLQTRHK--QWYFGKSLDGFTP 196 Query: 333 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 154 +GP IVT +E NP L + +NG +Q S T+ I I D+I LS +TL G II Sbjct: 197 MGPCIVTKNEFVNPPVLRICSRVNGELRQNSTTDLMITSIQDVIHELSQGITLKVGTIIA 256 Query: 153 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 GTP GVG+ PP+FL+ GD++ EIE IG + V+ Sbjct: 257 MGTPAGVGMGFIPPKFLKTGDIVECEIEGIGCLKNIVK 294 >UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymeth..; n=42; Bacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymeth.. - Yersinia pseudotuberculosis Length = 254 Score = 146 bits (353), Expect = 6e-34 Identities = 81/207 (39%), Positives = 114/207 (55%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 + +GLNY DH E +PP+ P IF K P + G + ++ D + + E EL VV+ Sbjct: 46 LFALGLNYVDHAAELDFSPPKEPLIFIKAPHSFTGHRQ-VSVRPDNIEYMHYEAELVVVV 104 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304 GK A ++ +HA DYV GYT+ D D+ +N L + K+ DT PIGPWIV + Sbjct: 105 GKPARYLNPAHAMDYVAGYTLCNDYAVRDYLENYYRPNLRV-KSRDTLTPIGPWIVDKAD 163 Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124 I NP NL ++ +NG Q+ NT I IP ++A LS +TL PGD+I TGTP G+ Sbjct: 164 IPNPHNLVIRTWVNGELCQRGNTADLIFDIPFLMAYLSEFITLQPGDMIATGTPKGL--- 220 Query: 123 RNPPEFLQPGDVITSEIENIGTFETRV 43 + PGD + E++ IG RV Sbjct: 221 ----SNVVPGDEVVVEVDGIGCLLNRV 243 >UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase; n=1; Methanopyrus kandleri|Rep: 2-keto-4-pentenoate hydratase hydratase - Methanopyrus kandleri Length = 264 Score = 146 bits (353), Expect = 6e-34 Identities = 84/205 (40%), Positives = 120/205 (58%), Gaps = 3/205 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496 K++C GLNY++H EE + + P P + K P+ V+G DT+KL + ++ V E+EL Sbjct: 65 KIICFGLNYREHVEELREMGMDVPSEPVMTMKAPTAVIGHLDTVKLPRE-ARRVDHELEL 123 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 VVIG++ KV A D VLG+TI D+ A D EK + Q + K+ DTF P+GPWI Sbjct: 124 AVVIGERCRKVSPEEARDAVLGFTIINDVTARDIEKRE--GQWVRAKSYDTFAPLGPWIE 181 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 T E P L ++ +NG +Q++ T+ + ++++ S VMTL PGDII TGTP G Sbjct: 182 TELE---PDGLEMELRVNGEVRQRATTDDMVRDPYELVSFTSRVMTLEPGDIIATGTPPG 238 Query: 135 VGVYRNPPEFLQPGDVITSEIENIG 61 VG ++P D I EIE IG Sbjct: 239 VGP-------MEPDDKIELEIERIG 256 >UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Burkholderiaceae|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 306 Score = 145 bits (351), Expect = 1e-33 Identities = 83/212 (39%), Positives = 118/212 (55%), Gaps = 7/212 (3%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQ--KLTPPE--LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499 ++ NY +H E +L P E P++F K ++VV P + ++ V E+E Sbjct: 92 RIFAAASNYYEHAREMGTELAPREESTPYMFMKAETSVV-PTLAEVVMPPHAERVDWEVE 150 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---QLLLGKAMDTFCPIG 328 L VVIGK + + AFDYV GYTI D+ A D + GK+ DTF P+G Sbjct: 151 LAVVIGKPGRHIAVADAFDYVAGYTILNDVSARDLNRRTDYPFKHDWFRGKSFDTFGPLG 210 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 PW+V I PQNL ++ ++NG Q NT + I I + I LS+++TL PGD+I TG Sbjct: 211 PWLVPRACIAEPQNLRMRLAVNGEMMQDGNTGEMIFSIAEQIHYLSSILTLQPGDLIATG 270 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 52 TP GVG+ R +LQPGDV+ + I+ IG+ E Sbjct: 271 TPTGVGMGRG--IYLQPGDVMVASIDGIGSIE 300 >UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 356 Score = 145 bits (351), Expect = 1e-33 Identities = 76/209 (36%), Positives = 114/209 (54%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 DK++ VG NY+ H E P+ P +F +FPS+ VG + + +S E EL V Sbjct: 139 DKIIAVGFNYRGHLIETGTPLPDYPSLFVRFPSSQVGHGQPV-VAPSLSGEFDFEGELAV 197 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 +IG+ A +V + A D+V+GY+ + D++ + + Q+ GK IGPW+ T+ Sbjct: 198 IIGRPAWRVAEADAMDHVVGYSCFAENSVRDYQAHAR--QVTAGKNFLASGAIGPWLTTA 255 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DE+G+P L + +NG Q+ I IP +IA ++ LLPGDII TGTP GVG Sbjct: 256 DEVGDPSTLELTTRLNGAVVQQDRLTSLIFTIPQLIAYITRFTRLLPGDIISTGTPDGVG 315 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 R+P +L PGDV+ +I +G V Sbjct: 316 FLRDPKIWLAPGDVLEIDIPRVGLLRNAV 344 >UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomycotina|Rep: RIB40 genomic DNA, SC138 - Aspergillus oryzae Length = 582 Score = 145 bits (351), Expect = 1e-33 Identities = 82/222 (36%), Positives = 123/222 (55%), Gaps = 9/222 (4%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 529 + G D VL VG NY +H +E K P P IF K ++++GP + I L Sbjct: 75 ISGRD-VLAVGKNYVEHAKEFNASGYDASDKSDQPTHPVIFTKRATSIIGPEEPILLHPK 133 Query: 528 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 349 + V E E+ V+IGK ++ +A D+V GYTI D+ A + +++ K Q LGK+ Sbjct: 134 FTSTVDYEGEIGVIIGKPGFQISEENASDHVWGYTIVNDMTARERQRDHK--QFFLGKSP 191 Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169 DTFCP+GP V + + P+NL ++ +N +Q+++ + I IP +IA +S TL Sbjct: 192 DTFCPMGPVAVPKESL--PENLKIQTFVNQELRQEASLSDLIFSIPTLIATISAGQTLQT 249 Query: 168 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GD+I TGTP GVG P +FLQ GD I+ + +GT R+ Sbjct: 250 GDVIATGTPAGVGFGFRPMKFLQTGDEISVSVTGLGTLTNRM 291 >UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Lawsonia intracellularis PHE/MN1-00|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Lawsonia intracellularis (strain PHE/MN1-00) Length = 257 Score = 144 bits (349), Expect = 2e-33 Identities = 81/211 (38%), Positives = 120/211 (56%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+ +NY + +E + P P F K PS++VG I L ++ + VV E EL +V Sbjct: 51 KIICIDINYHEKAQELQQPIPTNPTFFFKPPSSIVGNGQPILLPTNIGR-VVSEAELCIV 109 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+ KV A +Y+ GYT A DI A D ++ + + KA +TFCP+GPWI T Sbjct: 110 IGQTCYKVTPEAASNYIFGYTCANDITAKDIQQQEYTTSH--AKAYNTFCPVGPWIET-- 165 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 ++ N +NL ++ SIN Q S T I ++I+ LSN+MTL PGD+ILTGTP G Sbjct: 166 DVPNIENLQIRNSINSELGQVSTTADMIFPPLELISFLSNIMTLNPGDLILTGTPKG--- 222 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34 + GD++ + IEN+G +EE+ Sbjct: 223 ----SLLISDGDIVQTSIENVGILINPIEEY 249 >UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Herpetosiphon aurantiacus ATCC 23779 Length = 293 Score = 144 bits (349), Expect = 2e-33 Identities = 76/175 (43%), Positives = 100/175 (57%), Gaps = 6/175 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQ------KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 V CVGLNY H E ++ PE P F K P+ + P I + VS+ + E+ Sbjct: 76 VFCVGLNYAAHARESLQAKGLEVKMPEHPVFFTKPPTAINSPTGEIVIDPAVSERIDWEV 135 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL VVIGK + A ++V GYT+ D+ A D + + Q GKA+D CP+GPW Sbjct: 136 ELGVVIGKAGKNISHEQAMEHVWGYTVINDVSARDLQMRHQ--QFFKGKALDGSCPMGPW 193 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 I+TSDE+ +P NL V+ +NG KQ+SNTN I IP +I LS MTL PGDII Sbjct: 194 IITSDELTDPHNLVVRLRVNGEIKQESNTNDLIFNIPTLIHVLSQGMTLEPGDII 248 >UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase; n=4; Deinococci|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase - Deinococcus radiodurans Length = 262 Score = 144 bits (348), Expect = 2e-33 Identities = 81/208 (38%), Positives = 119/208 (57%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+ + LNY DH E PE P +F K P+T + P+ + +K + E+EL +V Sbjct: 46 KVIALALNYADHVAELGFKAPEEPVMFLK-PNTSLLPHQGTVIYPRGAKFMHYEVELGIV 104 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+ A +V + A DYV GYTIA D+ D+ N + K DTF P+GP++V++D Sbjct: 105 IGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNY-YRPPMRAKGWDTFGPLGPYLVSAD 163 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +P NL ++ +NG +Q+ +T I K P++I +S MTL GD+ILTGTP GV Sbjct: 164 EVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKGV-- 221 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 + PGDV+ EI+ +G E V Sbjct: 222 -----SHVHPGDVMRLEIDGLGALENPV 244 >UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative FAA hydrolase family protein - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 282 Score = 144 bits (348), Expect = 2e-33 Identities = 82/189 (43%), Positives = 107/189 (56%), Gaps = 11/189 (5%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP-----------PELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517 V CVG NY H E + PE P IF K S++ P I L + +A Sbjct: 87 VFCVGKNYHAHAHEFTKSGFDAGATAAEAIPEHPIIFTKPSSSLARPFGDIPLWPGLDEA 146 Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337 V E EL VVIGK + + A D+V GYT+ D+ A D +K K Q LGK +D F Sbjct: 147 VDYEAELAVVIGKAGRFITAERALDHVFGYTVFNDVTARDLQKKHK--QWFLGKGIDGFG 204 Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 PIGPWIVT DE+ + N+ + C++NG ++QK++T I IP +I +S +TLLPGDII Sbjct: 205 PIGPWIVTKDEL-DIANVEITCTVNGEERQKTSTKDLIFDIPTLIEVISRSVTLLPGDII 263 Query: 156 LTGTPGGVG 130 TGTP GVG Sbjct: 264 ATGTPAGVG 272 >UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: Fumarylacetoacetate hydrolase family protein - Hyphomonas neptunium (strain ATCC 15444) Length = 277 Score = 143 bits (347), Expect = 3e-33 Identities = 78/212 (36%), Positives = 112/212 (52%), Gaps = 4/212 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQ----KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499 K+L +G+NY H E PE+ FNK + V GP D + L VS + E E Sbjct: 59 KILGIGVNYAAHAAESVSFINTAKPEVQKWFNKQATAVNGPYDPVHLPR-VSSQLDYEGE 117 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319 L VIGK V + A + V G+ I D DW+K + +++GK DT P GP + Sbjct: 118 LVAVIGKHGRHVPAERAMEIVAGFCIGCDYSVRDWQKASQT--MIMGKGFDTHAPFGPAL 175 Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 VT DE+G+ +L ++ +NG +Q IH + IA L+ TL PGD+I TGTP Sbjct: 176 VTPDELGDISDLEIRSFVNGELRQSGRPRDMIHDVGAQIAHLTAAFTLEPGDVIFTGTPA 235 Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GVG +PP++L+ GD + EI+ +G E + Sbjct: 236 GVGAGFDPPKWLKAGDRVRIEIDRLGHIENAI 267 >UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584; n=2; Vibrio|Rep: Putative uncharacterized protein VV1584 - Vibrio vulnificus (strain YJ016) Length = 259 Score = 143 bits (346), Expect = 4e-33 Identities = 78/207 (37%), Positives = 112/207 (54%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 + +GLNY DH E PP+ P +F K +T+ D+ + + E EL V+ Sbjct: 48 IFALGLNYADHASELAFEPPKEPLVFLKGANTLTAHQQPSYRPNDI-EFMHYECELVAVV 106 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304 GK+A V A DY+ G+TI D D+ +N L + K+ D+ CPIGPWIV D+ Sbjct: 107 GKEARNVKREDAMDYIQGFTICNDYAIRDYLENYYRPNLRV-KSRDSLCPIGPWIVDCDD 165 Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124 I + NL + +NG Q+ NT+ I +P +I LS+ MTL PGD+I TGTP G+ Sbjct: 166 IEDVNNLALTTHVNGELTQQGNTSDMIFDVPFLIEYLSSFMTLKPGDLIATGTPKGL--- 222 Query: 123 RNPPEFLQPGDVITSEIENIGTFETRV 43 + +QPGDV+ IE +G+ E V Sbjct: 223 ----KDIQPGDVVRCTIEGVGSLENPV 245 >UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: Fumarylacetoacetate hydrolase family protein - Hyphomonas neptunium (strain ATCC 15444) Length = 281 Score = 143 bits (346), Expect = 4e-33 Identities = 78/208 (37%), Positives = 114/208 (54%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+GLNYK+H +E P P +F K ++V P+ L+ VS+ E E+ VV Sbjct: 75 KLVCLGLNYKNHVDETHNDLPPNPALFTKVADSLV-PHGEAVLRPKVSEQFDYEGEICVV 133 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK + A D+V GYTI D D++K+ + GK +GPWIVT+D Sbjct: 134 IGKGGRHISRETALDHVFGYTIMLDGSVRDYQKHS----VSAGKNFWRSGALGPWIVTAD 189 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 EI +P + ++ +NG Q + + ++ IP IA +S L PGD+I TGTPGGVG Sbjct: 190 EIPDPSVMKLETRLNGETVQSTTADLMLYDIPTAIAYVSQWTPLAPGDVIATGTPGGVGA 249 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 R PP +++ GDVI ++ IG V Sbjct: 250 RRKPPLWMKAGDVIEVDVSQIGVLSNPV 277 >UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydrolase; n=1; Burkholderia xenovorans LB400|Rep: Putative fumarylacetoacetate (FAA) hydrolase - Burkholderia xenovorans (strain LB400) Length = 257 Score = 142 bits (345), Expect = 5e-33 Identities = 79/204 (38%), Positives = 113/204 (55%), Gaps = 1/204 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 ++ VG+NY H E P +P F + +GP + I ++ ++ V E EL +V Sbjct: 55 RLFAVGMNYVGHIAEAGAKTPVIPQFFMMPTTAAIGPGEAI-VRPREAQVVHHEAELAIV 113 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK-ISQLLLGKAMDTFCPIGPWIVTS 310 IG++ ++D A D+V GYT A D+ + + LL+GKA DTFCP+GP I T Sbjct: 114 IGRRGRRIDVERALDHVFGYTCANDVSERVIQNREMGYGCLLVGKAFDTFCPLGPVIATG 173 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 + GN L V+ S+NG +Q NT+ + +P I++ LS +TLLPGD+ILTGTP GVG Sbjct: 174 LDAGN---LRVRASVNGSPRQDGNTSDLLFTVPHIVSYLSQAVTLLPGDVILTGTPSGVG 230 Query: 129 VYRNPPEFLQPGDVITSEIENIGT 58 L GDV I+ IGT Sbjct: 231 P-------LLSGDVCEITIDGIGT 247 >UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9; Ascomycota|Rep: Degradation of aromatic compounds - Pichia stipitis (Yeast) Length = 293 Score = 142 bits (345), Expect = 5e-33 Identities = 74/212 (34%), Positives = 113/212 (53%), Gaps = 5/212 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 V CVGLN+ H +E TPP P IF K +V + I + E EL +VI Sbjct: 79 VKCVGLNFMKHIQEGGRTPPPFPSIFYKTSFSVADFGEDIPIPKIAQSKCDYEGELCIVI 138 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGKAMDTFCPIGPWIV 316 GK + A YV GY D+ + +W+K+ + + Q K+ D + P+GP +V Sbjct: 139 GKTGKNIKEEEALSYVAGYVTGNDVSSRNWQKDPEFAGSVPQWCFSKSFDKYAPLGPALV 198 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 + I NP NL+++ ++NG +Q +NT+ + +P II+ +S TL G +I+TGTP G Sbjct: 199 SPQVIQNPGNLSLQTTVNGEIRQDANTDDLLFGVPRIISFISQSTTLEMGTVIMTGTPSG 258 Query: 135 VGVYRNP-PEFLQPGDVITSEIENIGTFETRV 43 V + P P +LQ GDV+ I+ IGT ++ Sbjct: 259 VALGMKPTPVYLQNGDVVEVAIDQIGTLSNKM 290 >UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=9; Proteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Burkholderia cenocepacia PC184 Length = 306 Score = 142 bits (343), Expect = 9e-33 Identities = 76/210 (36%), Positives = 115/210 (54%), Gaps = 1/210 (0%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K+LCVGLNY DH E P +F +F S+++G + I L S+ + E EL Sbjct: 90 NKILCVGLNYLDHSMETGFAKQTYPTVFARFASSLIGHDQPIALPAQSSQ-LDYEGELVA 148 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIGK + A D+V GY++ D+ D++ + Q +GK D GPW VT+ Sbjct: 149 VIGKAGRGITRERALDHVAGYSLFNDVTLRDYQF--RTPQWTMGKNFDGTGGFGPWFVTA 206 Query: 309 DEIGNP-QNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 DE+ + L ++ +NG Q+++T+ I I ++ LS VMTL GD+I+TGTP G+ Sbjct: 207 DELPRGCKGLRIQTRLNGAVVQEASTSDMIFDIETLVVMLSEVMTLQAGDLIVTGTPAGI 266 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G+ R P +++ GDV EIE +G V Sbjct: 267 GMAREPQLWMKAGDVCEVEIEQLGVLRNAV 296 >UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=6; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 291 Score = 141 bits (342), Expect = 1e-32 Identities = 73/211 (34%), Positives = 117/211 (55%), Gaps = 1/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+G N+ DH +E P P IF + ++++ D + ++ VS+ + E EL VV Sbjct: 79 KIVCLGHNFYDHAKEGGNLKPVYPLIFFRGATSLIAHGDPV-IRPFVSEKLDYEAELVVV 137 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK V +A D+V GY D+ D++K + +Q +GK D GPW+VTSD Sbjct: 138 IGKTGRHVKRENALDHVFGYACFNDVSVRDYQK--RTAQWTIGKNFDGTGAFGPWLVTSD 195 Query: 306 EIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 E+ L ++ +NG Q++NT I + + I L+ +TL PGD+++ GTP GVG Sbjct: 196 ELPPGAAGLKLELRLNGEAMQRANTADMIWSVAETIELLTECLTLEPGDVVVMGTPAGVG 255 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 R PP +++ GD + +IE IG V++ Sbjct: 256 FARTPPVWMKAGDRVEVDIEGIGVLSNVVQD 286 >UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Polynucleobacter sp. QLW-P1DMWA-1 Length = 309 Score = 141 bits (342), Expect = 1e-32 Identities = 85/220 (38%), Positives = 118/220 (53%), Gaps = 9/220 (4%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTP-----PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505 DK LCVG NY+ H EE K T P+ P F K S + G N T+ ++K + E Sbjct: 91 DKFLCVGKNYRTHLEELKRTNLIKEIPQEPTSFIKLNSCLSGHNATVVRPKGITK-LDYE 149 Query: 504 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPI 331 EL V+GK+A S A DY+ G TI D+ D + + S + GK + F P+ Sbjct: 150 PELVFVMGKRALGAKKSEAMDYIGGVTILNDLTCRDLQLREVASGSRFWTGKNIPGFGPL 209 Query: 330 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151 GP I+T DEI NP +L + CS+NG ++ + NT I KI DI+ S + + GD+ T Sbjct: 210 GPEIITIDEIPNPYDLWMTCSVNGEERMRVNTQDQIWKISDILEHFSRFIPIEAGDMFST 269 Query: 150 GTPGGVGVYRNPPE--FLQPGDVITSEIENIGTFETRVEE 37 G PGGV V + E +L+PGDV+ I+ I T T + E Sbjct: 270 GAPGGVAVGKENAEALYLKPGDVVECAIDGISTLRTTIAE 309 >UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Syntrophobacter fumaroxidans MPOB|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 235 Score = 141 bits (342), Expect = 1e-32 Identities = 83/224 (37%), Positives = 117/224 (52%), Gaps = 14/224 (6%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTP--------PELPFIFNKFPSTVVGPNDTIKLKMDVSK--- 520 K++ +GLNY+ H E PE P +F K P+ ++GP ++I + + + Sbjct: 19 KIIALGLNYRAHIAESTTVKVRGFTDEVPEEPILFPKTPNVLIGPGESIVIPAFLKEYGF 78 Query: 519 ---AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 349 E EL V+I + V A +V GYT D+ + + + GK++ Sbjct: 79 PEPRTDYEAELAVIIKDECKNVGPGDALKHVFGYTCMNDVSQRNLQTGDRAGWFR-GKSL 137 Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169 DTF PIGP IV D++G+P NL + C +NGV Q SNT I KIP+IIA +S L+P Sbjct: 138 DTFGPIGPVIVRPDDLGDPHNLRICCRLNGVTVQDSNTGSMIFKIPEIIAFVSRNFKLMP 197 Query: 168 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 GD+I+TGTP GVG R+ GDV+ EIE IG V E Sbjct: 198 GDVIVTGTPSGVGPIRH-------GDVVEVEIEKIGILRNPVVE 234 >UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isomerase; n=4; Halobacteriaceae|Rep: 2-hydroxyhepta-24-diene-1,7-dioate isomerase - Haloarcula marismortui (Halobacterium marismortui) Length = 257 Score = 141 bits (342), Expect = 1e-32 Identities = 77/209 (36%), Positives = 115/209 (55%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+C+G NY DH EE P+ P +F K P+ V + + + + E EL VV Sbjct: 59 KVVCIGRNYADHAEEMDSELPDRPMLFLKAPNAVASHGKHLTMPSGKER-IDYEAELGVV 117 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++ V S A D V GYT DI D ++ ++ + GKA D CPIGP + T + Sbjct: 118 IGEQCRNVSESGAMDVVAGYTCVNDISNRDDQRREQ--NWVRGKAFDNACPIGPLVATPE 175 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + P++ +++ +NG KQ S+ I +P++IA +++ MTL PGD+I TGTP GVG Sbjct: 176 HV--PEDASIELRLNGETKQSSSREHLIFSVPELIAEITSYMTLEPGDVIATGTPEGVGP 233 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVE 40 ++ GD + EIE IGT + V+ Sbjct: 234 -------MEDGDEVEVEIEGIGTLKHSVK 255 >UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rhodobacterales bacterium HTCC2654|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rhodobacterales bacterium HTCC2654 Length = 279 Score = 141 bits (341), Expect = 2e-32 Identities = 79/209 (37%), Positives = 112/209 (53%), Gaps = 4/209 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQK----LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499 +VLC+GLNYKDH E K T P+ P +F +F +++ +++ + VS+ V E E Sbjct: 68 QVLCIGLNYKDHRAETKGEVGTTYPDNPIVFMRFATSLAAHGESLPIPK-VSEVVDYEAE 126 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319 L V+IGK + + A +V GY DI DW+ K Q GK P GP + Sbjct: 127 LAVIIGKGGRYIAKADAMSHVAGYAPFNDISMRDWQM--KGEQWGPGKNFPKSGPFGPVM 184 Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 VT DE+G+ ++ ++G Q+S I IP +I+ SN + L PGD+I+TGTPG Sbjct: 185 VTPDEVGDLGETGIRLILDGEVLQESWIKHLIFDIPTLISYCSNFVELRPGDVIVTGTPG 244 Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFE 52 GVG R PP L PG E++ IG E Sbjct: 245 GVGFVRKPPILLAPGKTCVVEVDGIGRLE 273 >UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=3; Dehalococcoides|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Dehalococcoides sp. BAV1 Length = 253 Score = 140 bits (339), Expect = 3e-32 Identities = 79/179 (44%), Positives = 105/179 (58%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ +GLNYK H E P+LP IF K S ++GP D I +K S+ V E EL V+ Sbjct: 56 KIIAIGLNYKAHAGEMAEDLPKLPLIFFKNASGIIGPEDNI-IKPGQSERVDYEGELAVI 114 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 I KK + AFDY+LGY+ D+ A D +K Q K DTF GPWI T Sbjct: 115 IRKKTRNIKPEDAFDYILGYSCFNDVTARDLQKID--GQWSRAKGFDTFAVCGPWIET-- 170 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 E+ +PQ ++ +NG KQ+++T I IP I++ +S VMTLLPGDII TGTP G+G Sbjct: 171 EL-DPQVQLLETYLNGKLKQRTSTADMIFSIPRIVSFISEVMTLLPGDIIATGTPSGIG 228 >UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 250 Score = 140 bits (338), Expect = 4e-32 Identities = 80/208 (38%), Positives = 115/208 (55%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVG NY DH E P+ P +F K P+TV P + D + + E EL V Sbjct: 55 KIICVGKNYYDHAMEMGEGVPDRPILFIKAPNTVNHPEGEVSAP-DFVERLDYEGELAFV 113 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 + K+A V + DY+LGYT D+ A D +K+ Q GK+MD F PIGP + +D Sbjct: 114 VKKRAKNVKAEEYGDYILGYTCLNDVTARDIQKSD--GQWSRGKSMDGFAPIGPLV--TD 169 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +L ++ +NG Q S T+ F+ KIP ++ ++ MTL PGD++ TGTP G+G Sbjct: 170 EVDG-SDLKIETRLNGKTVQSSRTSLFMTKIPALMEFITASMTLEPGDVVTTGTPAGIGA 228 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 +QPGDV+ EIE IGT + Sbjct: 229 -------MQPGDVVEVEIEGIGTLRNYI 249 >UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2- hydroxymuconate Delta-isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase) (OPET decarboxylase)]; n=42; Proteobacteria|Rep: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2- hydroxymuconate Delta-isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase) (OPET decarboxylase)] - Escherichia coli Length = 429 Score = 139 bits (337), Expect = 5e-32 Identities = 78/212 (36%), Positives = 114/212 (53%) Frame = -3 Query: 678 HGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499 H + + +GLNY DH E + PPE P +F K P+T+ G N T ++ + + + E E Sbjct: 220 HPHGTLFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQT-SVRPNNIEYMHYEAE 278 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319 L VVIGK+A V + A DYV GYT+ D D+ +N L + K+ D P+ I Sbjct: 279 LVVVIGKQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYRPNLRV-KSRDGLTPMLSTI 337 Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 V + I +P NL ++ +NG +Q+ T I +P +IA LS MTL PGD+I TGTP Sbjct: 338 VPKEAIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPK 397 Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G+ + PGD + E+E +G R+ Sbjct: 398 GL-------SDVVPGDEVVVEVEGVGRLVNRI 422 Score = 74.5 bits (175), Expect = 2e-12 Identities = 48/156 (30%), Positives = 70/156 (44%) Frame = -3 Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430 PP+ F K +TV+G + I + V+ + +++GK A+KV A +Y+ G Sbjct: 31 PPKTAVWFIKPRNTVIGCGEPIPFPQ--GEKVLSGATVALIVGKTATKVREEDAAEYIAG 88 Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 Y +A D+ + + K D FCPIG + S N NL + ING Sbjct: 89 YALANDVSLPE---ESFYRPAIKAKCRDGFCPIGETVALS----NVDNLTIYTEINGRPA 141 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 NT +++ LS TL PGD IL GTP Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTP 177 >UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family protein; n=13; Campylobacter|Rep: Fumarylacetoacetate hydrolase family protein - Campylobacter jejuni subsp. jejuni CF93-6 Length = 292 Score = 139 bits (336), Expect = 7e-32 Identities = 77/214 (35%), Positives = 115/214 (53%), Gaps = 6/214 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 502 ++C+G+N+ DH +E +K E P F K + P +I L DV+ + E Sbjct: 77 IICLGINFLDHAKESAQFKGEKFEEREYPVYFGKRCNQATAPFGSISLHADVTSQLDYEC 136 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 322 EL ++ K A K+ + A DY+ GYTI +I A D +K K Q K+++ +GP+ Sbjct: 137 ELAFILSKDAYKIKAEDAKDYIFGYTIINEISARDLQKRHK--QFYRAKSLEGSTIMGPY 194 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 I + DEI P L++K +N +Q SNT FI I ++ LS+ M L G II GTP Sbjct: 195 ITSVDEIAYPPELHLKSYVNKELRQNSNTKFFIFDIGYVLEELSSGMLLKAGTIISMGTP 254 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 GVG+ NPP FL+ GD + IEN+G +++ Sbjct: 255 SGVGMGLNPPVFLKKGDEVRCVIENLGELCNKIK 288 >UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=5; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 287 Score = 138 bits (334), Expect = 1e-31 Identities = 73/211 (34%), Positives = 115/211 (54%), Gaps = 3/211 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496 K L +GL++K +E + + PE FNK + + GP D + + VS + E EL Sbjct: 76 KFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVHMPR-VSSELDYEGEL 134 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 +VIGK+ +S A + G+ + D DW++ + L GK+ DT PIGPW+ Sbjct: 135 ALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTATL--GKSFDTHGPIGPWLT 192 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 T DE+ +P +L ++ ++G +Q NT+ ++ ++IA LS TL PGDI+ TG+P G Sbjct: 193 TFDEV-DPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEPGDILATGSPTG 251 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G Y PP +L+ G + EIE +G E + Sbjct: 252 AGQYMRPPTYLKTGQTVRVEIEGLGHIENMI 282 >UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Actinomycetales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Arthrobacter sp. (strain FB24) Length = 290 Score = 138 bits (334), Expect = 1e-31 Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 1/202 (0%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 V+ +GLNY H E PE+P +F K +TV GP D + +S+ E+EL VVI Sbjct: 80 VVGIGLNYAGHAAESGAAVPEVPVVFLKPSNTVAGPFDDAPIP-PLSRKYDWEVELAVVI 138 Query: 483 GKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 G++AS + S A V GY +A D+ D++ Q + GK++ P+GPW V + Sbjct: 139 GQRASYLKSVDEAAGCVAGYVLANDLSERDYQLPGAAGQWVKGKSLPASTPLGPWFVPAA 198 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 ++ +P L ++ +NG +Q S+T I +P ++ LS M L PGD+ILTGTP GV + Sbjct: 199 DL-DPSALRLRTWVNGELRQDSSTADLIFDVPAVVHHLSQFMVLEPGDVILTGTPEGVAL 257 Query: 126 YRNPPEFLQPGDVITSEIENIG 61 P +LQ GDV+ E+E +G Sbjct: 258 SGRFP-YLQDGDVLELEVEGLG 278 >UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Marinomonas sp. MED121 Length = 298 Score = 138 bits (333), Expect = 2e-31 Identities = 76/203 (37%), Positives = 113/203 (55%), Gaps = 1/203 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+C+GLNY DH +E P+ P +F + S+++ P ++ VS + E EL ++ Sbjct: 82 KVICLGLNYMDHIKEGGYKVPDYPALFMRSHSSLM-PAQAPMVRPKVSVQLDYEAELMLI 140 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +GK + S A DYV GYTI D D+++ K Q GK D IGP IVT D Sbjct: 141 VGKHGRHIPESKALDYVFGYTIFNDGSVRDYQR--KTHQWTPGKNFDNTGAIGPIIVTPD 198 Query: 306 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 E+ L ++ + Q +NT++ + + +IA +S+ TL PGD+I GTP GVG Sbjct: 199 ELPEGAHGLKIETRVGDEILQSANTSEMLWSVARVIAEISSYTTLEPGDLIAMGTPPGVG 258 Query: 129 VYRNPPEFLQPGDVITSEIENIG 61 R+P +L+PG+V+ EIE IG Sbjct: 259 HARSPARWLEPGEVVEVEIEGIG 281 >UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Desulfovibrio|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Desulfovibrio desulfuricans (strain G20) Length = 264 Score = 137 bits (332), Expect = 2e-31 Identities = 78/202 (38%), Positives = 111/202 (54%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVG+N++DH EE PE P F K S V+G + L + S V E EL VV Sbjct: 50 KIVCVGMNFRDHAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAE-SGRVEHEAELGVV 108 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG+ A + +V GYT A D+ A D + + K DTF P+GPWI T Sbjct: 109 IGRAARNITPEDVPAHVFGYTCANDVTARDLQSRDGLFGRC--KGFDTFAPVGPWIET-- 164 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ + +L ++ +NG +Q+ +T + +I+A +S VMTLLPGD+ILTGTP GVG Sbjct: 165 EVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGTPAGVGP 224 Query: 126 YRNPPEFLQPGDVITSEIENIG 61 L+ GD + EI+ +G Sbjct: 225 -------LEDGDEVRVEIDGVG 239 >UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Acidobacteria bacterium Ellin345|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Acidobacteria bacterium (strain Ellin345) Length = 263 Score = 137 bits (332), Expect = 2e-31 Identities = 78/211 (36%), Positives = 111/211 (52%), Gaps = 1/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVG NYK H EE P+ P IF+K S ++ P IK +S+ V E EL V+ Sbjct: 63 KIVCVGRNYKAHAEELGHEIPKYPLIFSKPTSAIIAPGADIKRPAKLSQRVDYEGELGVI 122 Query: 486 IGKKASKVDSSH-AFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 IG++ + H Y+ GYT+ D+ A D + K Q K DTFCP+GP + + Sbjct: 123 IGRECRHIPEDHDVRSYIHGYTVVNDVTARDLQ--NKDGQWTRAKGFDTFCPVGP--IVN 178 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 D + + V+ +NG +Q NT+ FI + I+ +S VMTL PGD+I TGTP GVG Sbjct: 179 DALDPWTGVEVETRVNGAVRQHGNTSSFIFPLDVILRFISEVMTLFPGDLIATGTPEGVG 238 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 + GDV+ + IGT V + Sbjct: 239 P-------IIAGDVVEVSVAGIGTLRNPVAD 262 >UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Methylobacterium sp. 4-46|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Methylobacterium sp. 4-46 Length = 288 Score = 137 bits (331), Expect = 3e-31 Identities = 73/211 (34%), Positives = 115/211 (54%), Gaps = 1/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+G NY H E P + P +F + +++V + + ++ S E EL V Sbjct: 79 KIICIGRNYAAHAREGGAEPLDYPDVFMRGANSLVAHGEPL-IRPRCSDKFDYEGELVFV 137 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +G+KA V A + GY++ + D+++ + +Q +GK D GP +VT D Sbjct: 138 VGRKARHVGLDEACGIIAGYSVFNEGSIRDYQR--RATQWTMGKNFDGTGGFGPDLVTPD 195 Query: 306 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 E+ + L + ++NG Q NT+ FI + I+A L+ MTL PGD++LTGTP GVG Sbjct: 196 ELPDGADGLRLTTTLNGHVMQDGNTHDFIFPVARIVAILTEAMTLEPGDVVLTGTPSGVG 255 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 RNPP F++PGDV+ IE +GT V + Sbjct: 256 YARNPPVFIKPGDVVEVTIEKVGTLRNTVRD 286 >UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1; Streptomyces ambofaciens ATCC 23877|Rep: Putative maleylpyruvate isomerase - Streptomyces ambofaciens ATCC 23877 Length = 288 Score = 136 bits (330), Expect = 4e-31 Identities = 80/210 (38%), Positives = 113/210 (53%), Gaps = 1/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPF-IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 K++ +NY DH E + T +F K S+V+GP + I L K E EL V Sbjct: 77 KIIGAPVNYLDHKAEMEYTTSVADLGVFLKANSSVIGPGEDILLPYS-DKRTDQEGELGV 135 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIG+ A+ V + A +V GYT DI E K+ DTF P+GPW+VT+ Sbjct: 136 VIGRTAAHVSADDALGHVFGYTCVLDITVRSGEDRST------RKSFDTFTPLGPWVVTA 189 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI +P L+++C + G +Q++NT I + ++IA S+VMTL PGD+I TGTP GVG Sbjct: 190 DEIPDPDTLDLRCDVGGTTRQRTNTADLIFGVRELIAYTSSVMTLHPGDVIATGTPAGVG 249 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40 L GD + +IE +G E V+ Sbjct: 250 P-------LAHGDRVVLDIEKVGRLEVGVD 272 >UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; Filobasidiella neoformans|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 336 Score = 136 bits (329), Expect = 5e-31 Identities = 79/215 (36%), Positives = 126/215 (58%), Gaps = 2/215 (0%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSKAVVC 508 + G D V+CVG NY++H E + + + IF K ++++G N I V++ + Sbjct: 89 LRGRD-VICVGKNYREHAEWVRSLFKLVKYVVIFTKRATSIIGTNQEIYPHPRVTQTLDY 147 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E EL ++IGK ++ A+DYV G TI D+ A + +++ K Q +GK++DTFCP+G Sbjct: 148 EGELGIIIGKAGIQISREDAWDYVWGATIINDVTARERQRDHK--QFYIGKSLDTFCPMG 205 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 P+ V S + + +N+ ++ +NG +Q +NT+Q I IP +IA S +TL PGD+I TG Sbjct: 206 PYAVHSSVL-DWRNMMLETRVNGQIRQSANTSQLIFDIPALIATCSMGITLQPGDVISTG 264 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TP GV + + EFL+ DVI + +GT V Sbjct: 265 TPAGVCL--SSGEFLKHRDVIDISMSGLGTLSNTV 297 >UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_03001459; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03001459 - Ferroplasma acidarmanus fer1 Length = 274 Score = 135 bits (327), Expect = 8e-31 Identities = 80/211 (37%), Positives = 116/211 (54%), Gaps = 3/211 (1%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 +LC+GLNYK H E PE P +F+K + G + ++ + E EL V+ Sbjct: 69 LLCIGLNYKSHVSEHAGGKIPETPVVFSKANNAFTGNHSIVQTGNGMHMDY--EGELCVM 126 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK A V ++A +YVLGY I D+ + + K +Q LGK+ D F P GP+I + Sbjct: 127 IGKTARNVGEANALNYVLGYFIGNDVSSRLMQY--KTTQFFLGKSFDNFYPNGPYI-SIG 183 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV-- 133 EI +PQNL ++ +NG +Q SNT I + +I+ +S MTL PGD I TGTP GV Sbjct: 184 EINDPQNLTIQTRVNGELRQDSNTGLMIFPVNKLISYISQFMTLRPGDCISTGTPAGVIM 243 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 G+ + ++L GD + +I +G ET E Sbjct: 244 GMPESNQKWLGKGDKVEVQITGLGKLETTFE 274 >UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Actinomycetales|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 279 Score = 134 bits (325), Expect = 1e-30 Identities = 70/211 (33%), Positives = 114/211 (54%), Gaps = 4/211 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNY +H +E P+ P +F KFP ++GP D + + +KA+ E E+ V+ Sbjct: 69 KIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKALDWEGEMAVI 128 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIVT 313 IGK+A +V + A +Y+ GY + D D++ K Q GK+++ GPW+ T Sbjct: 129 IGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKSAGFGPWMTT 188 Query: 312 SD--EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 D E G + + G + Q + TN + +I ++++ L GD+I+TGTPG Sbjct: 189 PDSFEFGG----ELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDVIVTGTPG 244 Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETR 46 GVG RNP ++ G+ + EI +G E + Sbjct: 245 GVGHARNPQRYIGDGETVKVEIAGLGFIENK 275 >UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=4; Burkholderiales|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 284 Score = 134 bits (324), Expect = 2e-30 Identities = 72/211 (34%), Positives = 115/211 (54%), Gaps = 1/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+LCVGLNY DH +E P+ P +F + P+++VG +D ++ S + E EL VV Sbjct: 73 KILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVG-HDCAIVRPLASDTLDYEGELAVV 131 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK + A +V GY++ D +++ K Q +GK D GP++VT+D Sbjct: 132 IGKGGKHIAREDALSHVFGYSVFNDGSVREYQF--KSPQWTVGKNFDATGGFGPYVVTAD 189 Query: 306 EIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 E+ L ++ +NG Q ++T+ ++ + +IA +S +TL PGD+I+ GTP G+G Sbjct: 190 ELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEPGDVIVAGTPSGIG 249 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 R P ++ GDV IE IGT + + Sbjct: 250 WAREPKLLMRHGDVCEVSIERIGTLSNPIAD 280 >UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=6; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 292 Score = 134 bits (323), Expect = 3e-30 Identities = 76/219 (34%), Positives = 114/219 (52%), Gaps = 4/219 (1%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508 V G +K+ C+G+NY E K P+ P +F + P+++ G + L + SK + Sbjct: 75 VLGPEKIFCIGVNYAHRNAEYKDNSDLPKYPSVFMRTPASLTGHGQPLLLPPE-SKQLDY 133 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E E+ +VIGK ++ A ++ G T + DW + K + + GK D IG Sbjct: 134 EGEIGIVIGKAGRRIAKEDAHTHIAGLTCINEGTIRDWLHHGKFN-VTQGKNFDASGAIG 192 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 PWIVT+DE + N+ + +NG +Q+ T + +I+ LS TL PGDII TG Sbjct: 193 PWIVTADEFPDFDNIGLTTRVNGEVRQQDTTANLMFPFASLISYLSQFATLNPGDIIATG 252 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFE--TRVEE 37 TP G GV +PP FL PGDV+ E++ +G R EE Sbjct: 253 TPIGAGVRFDPPRFLVPGDVVEVEVDGVGVLANVVRAEE 291 >UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase; n=2; Actinomycetales|Rep: Possible fumarylacetoacetate hydrolase - Rhodococcus sp. (strain RHA1) Length = 281 Score = 134 bits (323), Expect = 3e-30 Identities = 82/211 (38%), Positives = 113/211 (53%), Gaps = 3/211 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKF-PSTVVGPNDTIKLKMDVSKAVV-CEIELT 493 +V+CVGLNYK H E TPP P +F ++ PS V D + ++A + E E+ Sbjct: 68 RVICVGLNYKAHAAEGGFTPPPYPTLFGRWTPSLSV---DGAPTPVPANEAGLDWEGEVA 124 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 IG + VD++ VLGY D+ A + K +Q LGK D P+GP +V Sbjct: 125 AFIGTRLESVDAATGQAGVLGYACFNDLTAR--KAQKLTAQWTLGKNGDRSGPLGP-LVP 181 Query: 312 SDEIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 + E+G+ L V+ +NG Q NT I + +IIA +S TL PGDII TGTP G Sbjct: 182 AGEVGDLSDGLRVQTRVNGTVVQDGNTRDLIFSVGEIIALVSETFTLHPGDIIATGTPEG 241 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 VG RNPP L PGD++ EI+ +G T + Sbjct: 242 VGYVRNPPWLLGPGDIVEVEIDKLGVLRTPI 272 >UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related protein; n=3; Archaea|Rep: 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related protein - Thermoplasma acidophilum Length = 250 Score = 134 bits (323), Expect = 3e-30 Identities = 69/213 (32%), Positives = 113/213 (53%), Gaps = 3/213 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+ +N++ H +E P P+ F KF + +VG N T ++ K + E E+ +V Sbjct: 38 KIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREIEK-LDYEGEIGIV 96 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCPIGPWIV 316 IGK+ ++ A +Y+ G+TI D+ A D+ E + + GKA D P+GP+IV Sbjct: 97 IGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALPVGPYIV 156 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 T DEI P L ++ +NG +Q T + + +I+ +S +TL PGD+I TGTP G Sbjct: 157 TRDEIRFP--LKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLITTGTPAG 214 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 V + ++L GD ++ + IG R+E+ Sbjct: 215 VAAF-TEAKYLSDGDTVSISVSGIGELVHRIED 246 >UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=2; Microbacteriaceae|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Leifsonia xyli subsp. xyli Length = 291 Score = 133 bits (322), Expect = 3e-30 Identities = 74/206 (35%), Positives = 111/206 (53%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 +V+ +G NY H E KL + +F+ +P+++ G T D++ V E EL V+ Sbjct: 83 QVIAIGANYAAHASELKLRSEKAATVFSLWPNSLAGHGGTTSWPGDLATQVDYEAELGVI 142 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK A V + A DYV GYT+ DI A D + ++ +Q K+ D F P GP VT+D Sbjct: 143 IGKPARDVLAQDALDYVWGYTVVNDITARDLQFSE--AQWSRCKSFDGFTPNGPVAVTAD 200 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ +PQ+L + +++G Q ++T + + +II LS T+ G +I TG+PGG G Sbjct: 201 EVPDPQDLWLTTNVDGAILQDASTADMVRSVAEIIEFLSRSATIPAGTLISTGSPGGAGY 260 Query: 126 YRNPPEFLQPGDVITSEIENIGTFET 49 R PP FL +T I IG T Sbjct: 261 SRTPPVFLHDRSTVTVSIGGIGYLTT 286 >UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Mesorhizobium sp. BNC1|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 307 Score = 132 bits (320), Expect = 6e-30 Identities = 86/224 (38%), Positives = 116/224 (51%), Gaps = 23/224 (10%) Frame = -3 Query: 663 VLCVGLNYKDHCEE----------------QKLTPPELPFIFNKFPSTVVGPNDTIKLKM 532 + C+G NY DH E Q+ P+ F K +V GP + L Sbjct: 80 IYCIGANYADHIAEMQGGGTNGASVAAERKQQKEDGLKPWFFIKSSHSVCGPETKVALPA 139 Query: 531 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ------ 370 SK V E EL VVIG+K+ + +A V GYTIA D+ A D + + Q Sbjct: 140 -TSKKVDWEAELAVVIGRKSRDLTIENALTAVWGYTIANDLSARDLSRRPPLPQGSPFFF 198 Query: 369 -LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 193 K+ D CP+GPWIV++ +I + +L++ SING QKSNT+Q I + + +A L Sbjct: 199 DWTSHKSFDDSCPMGPWIVSASQIVDANDLDIGLSINGQPMQKSNTSQMIFTVAEQVAHL 258 Query: 192 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 61 S +TL PGDIILTGTP GVG RN L+P D ++ IE IG Sbjct: 259 SQRITLWPGDIILTGTPAGVGAGRNLS--LKPSDEVSVYIEGIG 300 >UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Planctomyces maris DSM 8797|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Planctomyces maris DSM 8797 Length = 310 Score = 132 bits (320), Expect = 6e-30 Identities = 80/221 (36%), Positives = 116/221 (52%), Gaps = 13/221 (5%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPE----LPFIFNKFPSTVVG-PNDTIKLKMDVSKAVVCEI 502 K+L + NY H EE E P++F K PST + P +K+ + E+ Sbjct: 91 KLLLLAGNYSKHIEEGGGKAEERQKTFPYVFMKPPSTTLTHPGQPVKIPEVSPDYIDWEL 150 Query: 501 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNK--------KISQLLLGKAMD 346 EL +VIGK V + A DYV GYT+ DI + N GK D Sbjct: 151 ELGIVIGKSCKGVSEAEALDYVAGYTVINDISDRKFRPNPGRTLREKDTFFDWQHGKWHD 210 Query: 345 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 166 TFCP+GP + +D+I +PQ L +K S+NG +Q ++T + I + I+ +S+ + L PG Sbjct: 211 TFCPMGPCVTPADDIPDPQTLKMKLSVNGNVEQDASTAEMIFPVAAIVEFISSFVQLEPG 270 Query: 165 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 D+I TGTP GVG +N +FL+ GDV+ +EI+ IG V Sbjct: 271 DVISTGTPSGVGASKN--KFLKNGDVMKAEIDQIGVLTNPV 309 >UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family protein; n=2; Cystobacterineae|Rep: Fumarylacetoacetate hydrolase family protein - Stigmatella aurantiaca DW4/3-1 Length = 257 Score = 132 bits (319), Expect = 8e-30 Identities = 78/210 (37%), Positives = 114/210 (54%), Gaps = 1/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVV-GPNDTIKLKMDVSKAVVCEIELTV 490 KV+C+G NY+ H EE P P +F K PST + GP I+L S+ V E EL + Sbjct: 59 KVVCIGQNYRKHAEEMGKPVPSEPLLFIK-PSTALNGPRSPIRLPK-ASQEVHYEAELGL 116 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIG++ D + A + G T D+ A D ++ + Q K+ DTF +GPW VT Sbjct: 117 VIGERLKNADEATAARAIWGLTCINDVTARDIQRREV--QHTRAKSYDTFACVGPWAVTG 174 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 +P +L + C +NG +Q S T+ + +++ +S++MTLLPGD++ TGTP GVG Sbjct: 175 L---SPADLRILCRVNGQVRQDSRTSDMVFNPAQLVSFISHIMTLLPGDLVSTGTPSGVG 231 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40 L GD++ E+E IGT VE Sbjct: 232 A-------LAAGDMVEVELEGIGTLANPVE 254 >UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=3; Bacillaceae|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Geobacillus kaustophilus Length = 262 Score = 132 bits (318), Expect = 1e-29 Identities = 79/202 (39%), Positives = 116/202 (57%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 V+ +G NY E+ + P++P F K S+VVGP + + V + V E EL VVI Sbjct: 56 VIGIGANYVASSEQLPVELPDIPVFFFKPSSSVVGPEAEVVIPSGVGE-VKFESELAVVI 114 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 304 GK+A +V + Y+ GYT+A D+ A + +GK+ DTF P+GP I T E Sbjct: 115 GKEAKQVSEEDVWSYIFGYTVANDVTAPQFFHPD--GHWTIGKSFDTFTPLGPVIET--E 170 Query: 303 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 124 + +P+ ++VK +NG +KQ S+T I I +I+ LS+VMTL PGD+ILTG+P G Sbjct: 171 L-DPRAVSVKARVNGEEKQNSSTKLMIISISKMISYLSHVMTLQPGDVILTGSPVGA--- 226 Query: 123 RNPPEFLQPGDVITSEIENIGT 58 E + PG VI +++ IGT Sbjct: 227 ----ELVGPGTVIECDVDGIGT 244 >UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Comamonas testosteroni KF-1 Length = 286 Score = 132 bits (318), Expect = 1e-29 Identities = 72/215 (33%), Positives = 114/215 (53%), Gaps = 6/215 (2%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508 +K++C NY DH +E Q+ E P + S ++ VS ++ Sbjct: 72 EKIVCAVRNYMDHHQEVLAAGMQRELSEEPPIFLRVWRSQTAHQGPIVR--PHVSDSLDW 129 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E EL V+IG+ + + A++++ GY+ D +W+ + K Q+ GK ++ G Sbjct: 130 EGELAVIIGQGGRDIAEADAWEHIAGYSCYNDASVREWQFHAK--QIASGKNFESTGAFG 187 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 PW+VT+DEI + L ++ +NG Q S+T I IP +IA S + TL+PGD+I+TG Sbjct: 188 PWMVTADEISPGRELKLETRLNGAVVQSSHTGHMIFSIPRLIAYASTIFTLVPGDVIITG 247 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TP GVG + P +F++ GDV+ EIE IG V Sbjct: 248 TPAGVGWSKKPQQFMKAGDVVEVEIEAIGLLRNPV 282 >UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6; Pezizomycotina|Rep: Contig An05c0060, complete genome - Aspergillus niger Length = 290 Score = 131 bits (316), Expect = 2e-29 Identities = 79/214 (36%), Positives = 112/214 (52%), Gaps = 7/214 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKL-KMDVSKAVVCEIELTV 490 + C+GLNY DH +E L PE+P +F K S ++GP +I + K E EL V Sbjct: 76 IRCLGLNYIDHAKEANLALPEVPILFTKPRSALIGPYPASISVPKCAQDGTSDYESELCV 135 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG-----P 325 VIG+ + +A DYVLGYT + D+ A + +Q K +D CPIG P Sbjct: 136 VIGRTGRDIPEENALDYVLGYTASNDVSARTLQM--ATAQWSFSKGLDESCPIGIDRTGP 193 Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 +V+ I +PQ L ++ NGV Q +T I I I+ LS TL G I LTGT Sbjct: 194 VLVSPSVIKDPQTLRIQGIHNGVVVQDGHTKDMIFSIKRQISYLSQGTTLEAGTIFLTGT 253 Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 P G+G +++P + L+ GD + I+ IGT +V Sbjct: 254 PAGIGYFKSPRDVLKDGDEFSVYIDKIGTLTNKV 287 >UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family protein; n=8; Desulfuromonadales|Rep: Fumarylacetoacetate hydrolase family protein - Geobacter sulfurreducens Length = 218 Score = 130 bits (314), Expect = 3e-29 Identities = 71/211 (33%), Positives = 113/211 (53%), Gaps = 2/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+LC+G NY +H +E P+ P +F K + V+G +TI + S+ E EL ++ Sbjct: 17 KILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIP-SYSRECHHEAELALL 75 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 313 IGK + A ++V GY +A D+ D E KK + K DT CP+ + V Sbjct: 76 IGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSF-VP 134 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 +D + +P +L++ +NG +Q +++ IH+IP I++ +S V TL PGD+ILTGTP GV Sbjct: 135 ADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTLEPGDVILTGTPAGV 194 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 G L GD + +E+ + V+ Sbjct: 195 GP-------LAAGDAVEAEVVGVAAIRVTVK 218 >UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Fumarylacetoacetate hydrolase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 291 Score = 130 bits (314), Expect = 3e-29 Identities = 77/215 (35%), Positives = 122/215 (56%), Gaps = 7/215 (3%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPEL---PFI-FNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 499 K++ N+K+H +E K P+I F + +VGP D I+ ++K + E+E Sbjct: 68 KLIHTAGNFKEHEDESKRVGWSHNVGPWIVFMQNVDAIVGPEDGIRYPDHLTKELDYELE 127 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL-LGKAMDTFCPIGPW 322 L+VVI + + A +YV GY I D+ A D ++++ S + K +D+FCPIGPW Sbjct: 128 LSVVINQDVGEFAPEDAMNYVAGYVIFNDVTARDIQRDEMKSGVFGFCKGIDSFCPIGPW 187 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 IVT+DEI NP +L ++ +NG +Q+S++++ IP+I+AR S + GDI+ TGT Sbjct: 188 IVTADEIPNPHDLKMELRVNGEPRQESHSSRMWTTIPEILARYS-PLGYSAGDIVTTGTV 246 Query: 141 GGVGVYRNPPE--FLQPGDVITSEIENIGTFETRV 43 GV +R E +L+ GD + E+E IG V Sbjct: 247 SGVAGFRVDAEDYYLRVGDSVECEVEKIGVLRNTV 281 >UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - Pseudomonas abietaniphila Length = 293 Score = 130 bits (313), Expect = 4e-29 Identities = 80/211 (37%), Positives = 113/211 (53%), Gaps = 1/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 +V VGLNY H + T PE P + K S +VG +D I+ ++ + E+EL V Sbjct: 69 RVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYPA-LTAQLDYEVELVAV 127 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 I + D A +LGYT DI A D K LL KAMD P+GPW+VT D Sbjct: 128 IARALG--DEPCASACLLGYTCGNDISARDAGKRIGRLDLLTQKAMDRTTPVGPWVVTLD 185 Query: 306 EIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 EIG Q +L+++ S+N +Q NT Q + I +++ + +TL PGD++ TG+ GVG Sbjct: 186 EIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARITLQPGDLVFTGSTHGVG 245 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 + FLQPGD + IE IG+ RV + Sbjct: 246 L--EDGRFLQPGDRVEVRIEGIGSMSNRVSQ 274 >UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate isomerase; n=1; Thermoplasma volcanium|Rep: 2-hydroxyhepta-2,4-diend-1,7-dioate isomerase - Thermoplasma volcanium Length = 268 Score = 130 bits (313), Expect = 4e-29 Identities = 71/211 (33%), Positives = 112/211 (53%), Gaps = 3/211 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+ +N++ H E P P+ F KF + +V N ++ + K + E E V Sbjct: 61 KIFLPAVNFRSHSAESDTRFPPKPYFFTKFSNALVANNSELRTPGTIKK-LDYEGETGAV 119 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCPIGPWIV 316 IGKK + + A+D + G+TIA D+ A D+ E + + GKA D P+GP+I Sbjct: 120 IGKKCYNIPAEDAYDCIFGFTIANDLSARDFQFPEMHPYGYNWVQGKAFDGALPVGPYIT 179 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 T DEI P L ++ +NG +QK T+ + D+I+ LS +TL PGDII +GTP G Sbjct: 180 TKDEIQFP--LEIETKVNGETRQKGTTDDMVFSFQDLISTLSQNITLEPGDIITSGTPAG 237 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 V + + +L+ GDVI + ++GT ++ Sbjct: 238 VAAF-SEKLYLKSGDVIEISVSSLGTLMNKI 267 >UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Archaeoglobus fulgidus|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Archaeoglobus fulgidus Length = 324 Score = 129 bits (312), Expect = 5e-29 Identities = 73/190 (38%), Positives = 106/190 (55%), Gaps = 3/190 (1%) Frame = -3 Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424 ++P + P +V+GP + + + ++ + E+E +V+GK+ V A DYVLGYT Sbjct: 134 QVPVGYKMNPYSVIGPEEPV-IWPSFTQILDYELEFGIVVGKRGKNVSKEDAMDYVLGYT 192 Query: 423 IAQDIGATDWEKNK-KISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQ 253 I DI A D E + K L L K D P+GP IVT DEI +P NL + +NG Sbjct: 193 IVNDISARDMEFIELKAMPLGPLKSKDFDNATPMGPCIVTKDEIKDPHNLKMVARVNGEV 252 Query: 252 KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 73 +++T KIPD+IA LS T+ PG ++L+GTPGG G + + L+PGDV+ EI Sbjct: 253 WSEASTKDMHWKIPDLIAHLSKDQTIHPGTVMLSGTPGG-GCGMHVGKLLKPGDVVELEI 311 Query: 72 ENIGTFETRV 43 E IG + Sbjct: 312 EGIGVLRNPI 321 >UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Halorubrum lacusprofundi ATCC 49239 Length = 304 Score = 129 bits (312), Expect = 5e-29 Identities = 71/205 (34%), Positives = 109/205 (53%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+G NY DH E P+ P +F K P+ + D I + + + E E+ VV Sbjct: 106 KIVCIGRNYADHAAELDNDVPDRPLLFLKPPNALASHGDEITVPAGKDR-IDWEAEIAVV 164 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++ VD+ A D V G+T D+ D + ++ + GKA D P+GP + T D Sbjct: 165 IGEQCKDVDADDAMDVVAGFTCMNDVSNRDDQDREQ--NWVRGKAFDGAAPLGPVMATPD 222 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 E+ P + +V+ +NG KQ S+ + + +P +I ++ +TL PGD+I TGTP GVG Sbjct: 223 EV--PADASVELRVNGETKQSSDRSYLMFDVPTLIEEITTYLTLEPGDVISTGTPEGVGA 280 Query: 126 YRNPPEFLQPGDVITSEIENIGTFE 52 L GD + EIE +GT E Sbjct: 281 -------LSDGDTVEVEIEGVGTLE 298 >UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase-related protein; n=4; Deinococci|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase-related protein - Deinococcus radiodurans Length = 250 Score = 128 bits (309), Expect = 1e-28 Identities = 78/209 (37%), Positives = 111/209 (53%), Gaps = 3/209 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496 K++CVG NY DH E +LP IF K P+ + P T++ S+ E EL Sbjct: 52 KIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGTVEYP-SWSENFHFEGEL 110 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 +VIG++A + + A VLGYT D+ A D +K Q KA D FCP+GPW+V Sbjct: 111 ALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQKTDL--QWFRAKAADRFCPLGPWLV 168 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 T + P ++ V+ +NG +Q T+ I + I+ L+ +TL PGD++LTGTP G Sbjct: 169 TQFD---PSDVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTRFVTLEPGDVVLTGTPEG 225 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFET 49 VG LQ GD + E++ IG ET Sbjct: 226 VGP-------LQRGDRVEVEVDGIGVLET 247 >UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Leptospirillum sp. Group II UBA|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Leptospirillum sp. Group II UBA Length = 267 Score = 128 bits (309), Expect = 1e-28 Identities = 76/203 (37%), Positives = 113/203 (55%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ VGLNY+ H E PE P +F K S ++ PN I+L +S+ V E E+ +V Sbjct: 60 KIIAVGLNYRAHGNEMGKPLPEEPLLFMKATSALLPPNGEIRLPR-MSRRVDFEGEIALV 118 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +GKKAS + +V G T A D+ A D +K K Q K+ DTFCP+GP I+T Sbjct: 119 MGKKASGISPEEVPLFVYGITCANDVTARDLQK--KDVQYTRAKSFDTFCPLGPVILTG- 175 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 P + ++ +NGV +Q++ + I +++ +S VMTL PGD+ILTGTP GVG Sbjct: 176 --ALPDDRRLRTEVNGVVRQEARASDMIFDPLTLVSFISQVMTLEPGDVILTGTPSGVGP 233 Query: 126 YRNPPEFLQPGDVITSEIENIGT 58 L P D ++ +E +G+ Sbjct: 234 -------LSPMDRVSVSLEGVGS 249 >UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomycotina|Rep: RIB40 genomic DNA, SC005 - Aspergillus oryzae Length = 299 Score = 128 bits (308), Expect = 2e-28 Identities = 75/213 (35%), Positives = 109/213 (51%), Gaps = 8/213 (3%) Frame = -3 Query: 657 CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND--TIKLKMDVSKAVVCEIELTVVI 484 CVGLNY H +E PP PFIF K P+T V + + ++ + E EL ++I Sbjct: 85 CVGLNYAKHIKEAGRKPPPFPFIFFK-PNTCVHDHGKPVVIPRIAQNDQADYEGELCLII 143 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGKAMDTFCPIGPWIV 316 GK A V HA +YV YT DI + +++ + Q K DTF P+GP +V Sbjct: 144 GKDAKDVSPEHALEYVAAYTAGNDISSRKLQRDPAYAGVVPQWGFSKGFDTFAPLGPVLV 203 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 + EI +P L++K ++G +Q + +I+ LS TL G +I+TGTPGG Sbjct: 204 AASEIPDPSQLHLKTIVDGEVRQDETVGDLLFDCKYLISYLSQGTTLQKGSVIMTGTPGG 263 Query: 135 VGVYR--NPPEFLQPGDVITSEIENIGTFETRV 43 +GV PP++L PG + +I IGT V Sbjct: 264 LGVGAGFKPPKWLVPGTQMDVQISQIGTLRNNV 296 >UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Marinomonas sp. MWYL1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Marinomonas sp. MWYL1 Length = 245 Score = 127 bits (307), Expect = 2e-28 Identities = 73/212 (34%), Positives = 112/212 (52%) Frame = -3 Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 N+K L L K E+ + PP+ P + K +T +G +IKL D AV L Sbjct: 43 NNKALAKSLE-KAFNEKPHVQPPKTPVLHIKTDNTHIGYGKSIKLPSDKG-AVFAGPSLG 100 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 +VIGKK ++VD+S+A D V G+T+ ++ + + + K DTFCPIGPW V Sbjct: 101 IVIGKKTTRVDASNALDCVAGFTVVNEVSLAETSFYRPAVK---AKCRDTFCPIGPWSVD 157 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + P L++K IN ++NT+Q I+ + +I++ +S+ MTL GDII+ GTP Sbjct: 158 KSAVSTPNKLSIKTFINDALVHETNTDQLIYSVEEIVSYISSFMTLEAGDIIIAGTP--- 214 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 R + PGD + +IE +G VE+ Sbjct: 215 --ERTADLAINPGDSVMIDIEGVGRLVNPVEQ 244 >UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Fumarylacetoacetate hydrolase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 285 Score = 127 bits (307), Expect = 2e-28 Identities = 70/212 (33%), Positives = 115/212 (54%), Gaps = 4/212 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTP---PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496 KV+C+GLNY H E PE P +F ++PST+ I + D + + E E+ Sbjct: 68 KVICIGLNYLKHVAEGSYGAEPLPEFPTLFARWPSTLTVDGAQIPVPTD-EEGLDWEGEV 126 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 +G++ S + A D V+GY+ D+ A K SQ +LGK D P+GP +V Sbjct: 127 VAWVGRELSCATADEALDAVVGYSTFNDVTAR--RAQKITSQWILGKNADRSGPLGP-LV 183 Query: 315 TSDEIGNPQN-LNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 + ++G+ ++ L V+ +NG Q ++T++ ++ + + +A +S +TL PGD++ TGTP Sbjct: 184 PAHDVGDLRDGLRVRTRVNGTTVQDASTDEMVYTVGETLAHISRTLTLRPGDLLATGTPS 243 Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GVG R P L PGD + E+E +G + Sbjct: 244 GVGYARTPAWLLHPGDHVEVEVEKLGVLRNTI 275 >UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1; n=1; Debaryomyces hansenii|Rep: Similar to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 289 Score = 127 bits (307), Expect = 2e-28 Identities = 74/212 (34%), Positives = 109/212 (51%), Gaps = 4/212 (1%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 V C+G+NYK+H + PP P +F K ++V N+ I + + E EL VVI Sbjct: 79 VKCIGMNYKEHLMGI-IEPPPYPQLFYKPRTSVADQNEDIPIPLFAQNTCDYEGELCVVI 137 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDW----EKNKKISQLLLGKAMDTFCPIGPWIV 316 GK ++ A YV GY D+ A DW E K+ QL K+ D + P+GP IV Sbjct: 138 GKTGKNINEEDALSYVAGYVSGNDLSARDWQYFPEYAGKVPQLGFSKSFDRYAPLGPAIV 197 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 +S I +P L ++ ING +Q T+ + I IIA +S TL G +I+TGTP G Sbjct: 198 SSKIIKDPHALQLQTRINGDLRQNCGTDDLLFGISRIIAFISQETTLEQGTVIMTGTPNG 257 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 G ++L+ GD++ I+ IGT + + Sbjct: 258 CGGIDG--KYLKDGDLVEVTIDQIGTLSHKTK 287 >UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Methanosphaera stadtmanae (strain DSM 3091) Length = 256 Score = 127 bits (307), Expect = 2e-28 Identities = 77/203 (37%), Positives = 111/203 (54%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNYKDH +E + P+ P +F K ++V+ N I + + + E EL +V Sbjct: 64 KIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAI-IYPSTTNMLDFEGELGIV 122 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 I +K S D+ + YTI D+ A D + K Q K+ DTFCP GP +VT Sbjct: 123 ILEKVSPCDNGTCN---VAYTIVNDVTARDLQS--KDGQWTRSKSYDTFCPCGPVVVTGI 177 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + NLN+K +N KQ+SNT I +++ +SN+MTL PGDII +GTP GVG Sbjct: 178 D---SSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVG- 233 Query: 126 YRNPPEFLQPGDVITSEIENIGT 58 L GD + EI+ +G+ Sbjct: 234 ------HLDVGDTVVVEIDEMGS 250 >UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 293 Score = 126 bits (303), Expect = 7e-28 Identities = 74/210 (35%), Positives = 113/210 (53%), Gaps = 7/210 (3%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFI-------FNKFPSTVVGPNDTIKLKMDVSKAVV 511 +KV+ NY H +E K + F K S++ GP D I L + V Sbjct: 77 NKVVAFPANYHAHIDEMKAGSGLISNFAAAGQGFFLKANSSLSGPADPIVLPNLDGREVH 136 Query: 510 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 331 E EL V+IGK+ + +A +V GY+ D E+ ++ K+ DTFCP+ Sbjct: 137 HESELAVIIGKRGRNIPRENALQHVFGYSCLIDAVVRGKEER------VMRKSYDTFCPL 190 Query: 330 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 151 GPW+VT++E+ +P N++++ ++NG +QK+NT I +P++IA S+VMTL PGDII + Sbjct: 191 GPWLVTAEEVPDPANIDIELTVNGEVRQKANTRALIVDVPEMIAMASSVMTLEPGDIIAS 250 Query: 150 GTPGGVGVYRNPPEFLQPGDVITSEIENIG 61 GTP GVG + PGD + I +G Sbjct: 251 GTPSGVGP-------MLPGDAVCITIAGVG 273 >UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; Dikarya|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 311 Score = 126 bits (303), Expect = 7e-28 Identities = 77/214 (35%), Positives = 114/214 (53%), Gaps = 5/214 (2%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG---PNDTIKLKMDV-SKAVVCEIEL 496 + C+GLNY +H +E L P++P +F K PST + P+ TI K V S + E E+ Sbjct: 99 IRCIGLNYVNHAKEVNLPMPDIPTLFMK-PSTSLADPFPSPTIIPKAFVASNSADFESEV 157 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 VIGK A V A DYVLG+T A D+ + + + + SQ K+ D CPIGP +V Sbjct: 158 AFVIGKDAKNVSEEEALDYVLGFTAANDVSSREAQFAQ--SQWCYSKSFDGACPIGPALV 215 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 ++ ++ ++ S+NG Q S + I +P I++ LS TL G II+TGTP G Sbjct: 216 NKNQANKFSDVKIEGSLNGKTVQSSRLDDLIFSVPKIVSFLSQGTTLPAGTIIITGTPAG 275 Query: 135 VGVYRNPPEFLQPGDVITSEIEN-IGTFETRVEE 37 VG P L+ GD + + +GT ++ E Sbjct: 276 VGWSSTPRITLKDGDEFRVFVSHGVGTLINKIVE 309 >UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; Eukaryota|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 228 Score = 126 bits (303), Expect = 7e-28 Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 4/183 (2%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC--EIELT 493 K++ +G NY DH +E P+ PF F K S+ + P++ +++ + V+ E+EL Sbjct: 10 KIVAIGRNYADHAKELGNAIPKEPFFFLKPTSSYLVPDNG---PVEIPRGVIVHHEVELG 66 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 319 VVIGK + S AFD+V GY++A D+ A + + K L K DTFCPIGP+I Sbjct: 67 VVIGKNGRDISPSAAFDHVAGYSLAVDMTARNVQDKAKAKGLPWSAAKGFDTFCPIGPFI 126 Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 I +P + + S+NG KQ T+ I IP +IA +S +M L GD++LTGTP Sbjct: 127 -PKHFIADPTKVGLHFSVNGTVKQSGLTSDMIFDIPQLIAFVSGIMKLEEGDLVLTGTPS 185 Query: 138 GVG 130 GVG Sbjct: 186 GVG 188 >UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; Eukaryota|Rep: Uncharacterized protein ZK688.3 - Caenorhabditis elegans Length = 214 Score = 125 bits (302), Expect = 9e-28 Identities = 70/180 (38%), Positives = 101/180 (56%), Gaps = 2/180 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVG NYKDH E P+ P +F K ++ + + I + E+EL VV Sbjct: 13 KIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPIVAPPGCQN-LHQEVELGVV 71 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 313 I KKAS++ S A DY+ GYT+A D+ A D+ E K + L K+ D CPIG ++ Sbjct: 72 ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 SD I NP ++ + C ING +Q+ T+ I IP ++ + TL GD++LTGTP GV Sbjct: 132 SD-IPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGV 190 >UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomycetales|Rep: Maleylpyruvate isomerase - Rhodococcus sp. (strain RHA1) Length = 275 Score = 125 bits (301), Expect = 1e-27 Identities = 66/203 (32%), Positives = 107/203 (52%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVGLNY +H +E PE P +F KF + GP D + + + + E EL V Sbjct: 69 KIICVGLNYANHIQEMGRDLPEYPTLFAKFKEALTGPYDDVIVPSYAAAQLDWEGELAFV 128 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +GK+A +V + A Y+ GY++ D D++ + Q GK + GP++ T+D Sbjct: 129 VGKQAYQVPEADAEQYIAGYSVMNDYTMRDYQ--YRTLQWDQGKTFEKTSGFGPFLTTTD 186 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 L K + G Q + T+ + ++ +S+++TL PGD+++TGTPGGVG Sbjct: 187 SYTFGGTLVTK--LEGQVVQSTTTDDLVFTPARLVEYISHIVTLQPGDVVITGTPGGVGH 244 Query: 126 YRNPPEFLQPGDVITSEIENIGT 58 R P ++Q G + IE +GT Sbjct: 245 ARKPGLYIQDGQTVEVTIEGLGT 267 >UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Nocardioides sp. JS614|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Nocardioides sp. (strain BAA-499 / JS614) Length = 269 Score = 124 bits (300), Expect = 2e-27 Identities = 79/210 (37%), Positives = 107/210 (50%), Gaps = 1/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+ +G NY H E P P +F K ++V+GP D I + E EL VV Sbjct: 68 KVVGIGRNYAAHAAELGNDLPTEPLMFLKPNTSVIGPGDPIFYPPQTQN-LHYEGELAVV 126 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS- 310 IG+ V A D + GYTI D+ A D +++ Q K D+FCP+GPWI T Sbjct: 127 IGRICRDVPPEQATDVIHGYTIGNDVTARDLQRSDV--QFTRAKGFDSFCPLGPWIETDL 184 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 D + +V+ +NG Q +T I IP +IA +S+VMTLLPGD+ILTGTP GVG Sbjct: 185 DPHDFAEGRSVQTHLNGDLVQDGSTKDLIFDIPTLIAYVSSVMTLLPGDVILTGTPEGVG 244 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRVE 40 + GD + I +GT V+ Sbjct: 245 P-------MDVGDEVEVSIAGLGTLTNPVK 267 >UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Corynebacterium jeikeium K411|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Corynebacterium jeikeium (strain K411) Length = 272 Score = 124 bits (299), Expect = 2e-27 Identities = 67/209 (32%), Positives = 108/209 (51%), Gaps = 1/209 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+ CVGLNY++H E P+ P +F K+ S + GP D + + ++S E EL V+ Sbjct: 74 KIFCVGLNYREHIAEMGHPIPDHPTLFVKYASALAGPFDEVVVPPELSAQADYEGELAVI 133 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +G+ F + GYT+ D DW+ + Q L GK +D GPW+V ++ Sbjct: 134 MGE----------FGQIAGYTVMNDFSQRDWQY--RTQQWLQGKNLDRSSGFGPWMVPTE 181 Query: 306 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 + ++ +NG +Q+ + + K D++ +SN +L PGD+I+TGTP GVG Sbjct: 182 HFDPIAEGAVLRTWVNGELRQEHSVADLVFKPQDLVDYISNFASLAPGDVIVTGTPEGVG 241 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 PP++L GD + I+ IG R+ Sbjct: 242 HGMTPPQYLADGDEVRIAIDGIGEICNRI 270 >UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase; n=2; Ostreococcus|Rep: Predicted fumarylacetoacetate hydralase - Ostreococcus tauri Length = 322 Score = 124 bits (299), Expect = 2e-27 Identities = 77/223 (34%), Positives = 116/223 (52%), Gaps = 14/223 (6%) Frame = -3 Query: 663 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508 + CVG NY +H E ++ PE P IF+K +++ +I + K V Sbjct: 102 IACVGKNYLEHVGEVDSTMPGISRMDVPEAPIIFSKASTSLNAHLGSIATRG--RKDVDY 159 Query: 507 EIELTVVIGKKASKVDSSHAFD-----YVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 343 E EL VIG++ +D + + YV+G++IA D+ A + +K + Q LGK+ DT Sbjct: 160 EGELVAVIGRECRDIDPGMSDEDVVKNYVIGWSIANDVTARELQKTHQ--QWFLGKSGDT 217 Query: 342 FCPIGPWIVTSDEIGNPQNL-NVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 166 CP+GPW+ D ++ ++N +Q+S +Q I + +IA +S TL G Sbjct: 218 HCPLGPWVCCDDGRAPALGAASITTAVNSEIRQRSTVDQLIWSVGALIACISRHQTLRVG 277 Query: 165 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 D +LTGTP GVG +PP FLQPGD IE +GT + V E Sbjct: 278 DCVLTGTPSGVGAGFDPPRFLQPGDACEVTIEGVGTLKNTVVE 320 >UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE DECARBOXYLASE; n=19; Proteobacteria|Rep: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE DECARBOXYLASE - Brucella melitensis Length = 311 Score = 123 bits (297), Expect = 4e-27 Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 2/212 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQK--LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 K++CVG+N+ D EE K P P +F +FP + G + ++ S + E E+ Sbjct: 99 KIICVGVNFPDRNEEYKDGQAAPANPSLFVRFPRSFTGHERPL-MRPPESPQLDYEGEIA 157 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 +VIGK ++ A D++ T+ + DW ++ K + + GK D IGPW+V Sbjct: 158 IVIGKGGRRIAEKDALDHIAALTLCNEGTIRDWVRHAKFN-VTQGKNFDATGSIGPWLVP 216 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + ++ + +NG +Q+ T++ I II +S TL+PGD+I+ GTP G Sbjct: 217 YTDESQIADIQLTTRVNGEVRQQDRTSRMIFSFRKIINYVSTFTTLVPGDVIVCGTPTGA 276 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 G +PP +L+PGDV+ E E IG + + Sbjct: 277 GARFDPPIWLKPGDVVEVEAEGIGLLRNTIAD 308 >UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; n=1; Pseudomonas alcaligenes|Rep: Putative uncharacterized protein xlnF - Pseudomonas alcaligenes Length = 287 Score = 123 bits (296), Expect = 5e-27 Identities = 77/219 (35%), Positives = 112/219 (51%), Gaps = 10/219 (4%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTP-----PELPFI-----FNKFPSTVVGPNDTIKLKMDVSKA 517 K++ +NY DH +E E+ I F K S+ VGP++ I L + Sbjct: 82 KIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVGPDEGISLPAVEGRR 141 Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337 E+EL +VIGK+ +V A V GY I DI E K+ D+F Sbjct: 142 FDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRS------YRKSFDSFT 195 Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 +GPW+VTSD G+P+ + S+NG Q+Q +NTN + + II+ S+ TL PGD+I Sbjct: 196 VMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIISVASHAYTLYPGDVI 255 Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 LTGTP GVG ++ GD I++ I+ IG+ E V+ Sbjct: 256 LTGTPAGVGP-------IKAGDKISASIDRIGSMEVPVK 287 >UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Hyperthermus butylicus DSM 5456|Rep: Fumarylacetoacetate (FAA) hydrolase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 338 Score = 123 bits (296), Expect = 5e-27 Identities = 67/209 (32%), Positives = 110/209 (52%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +K++C+G+NY+ H E + P P +F K +++VGP D + + V + E+EL Sbjct: 120 EKIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDPVVVH-SVGLKLDGEVELAA 178 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIG A + S A D V G+ + D+ + ++ ISQ K+ DT+ P GP IV Sbjct: 179 VIGIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSHDTYAPTGPIIVPR 238 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 + + + ++ ++G+ ++ NT +H + DI++ S L+PGDII TGTP G Sbjct: 239 HMV-SIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVPGDIICTGTPAGTM 297 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 P + +PG V+ + IG E RV Sbjct: 298 PDGKPAKTPEPGSVMRACARGIGCIENRV 326 >UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albicans IPF5534; n=2; Ascomycota|Rep: Similar to CA3735|IPF5534 Candida albicans IPF5534 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 208 Score = 121 bits (292), Expect = 1e-26 Identities = 74/208 (35%), Positives = 105/208 (50%), Gaps = 6/208 (2%) Frame = -3 Query: 648 LNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKL-KMDVSKAVVCEIELTVVIGKK 475 +NY H +E L PP P IF K P T VG N+ I + K+ E E VVI K Sbjct: 1 MNYMKHIQEGSLPPPPKPQIFYK-PRTSVGDHNEAIAIPKIAQENQCDYEGEFCVVIVKT 59 Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNK----KISQLLLGKAMDTFCPIGPWIVTSD 307 + A +YV GY + D+ A W+ + I Q K+ D + P+GP + ++ Sbjct: 60 GKHIKEEDALNYVAGYIVGDDVSARIWQYHPDYSGNIPQWYYSKSFDRYAPLGPALFSTR 119 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 I NP L ++ ING +Q +NT+ + I IIA LS TL G +I+TGTP GVG Sbjct: 120 VIKNPHTLQLQTRINGELRQDANTDDLLFNIQKIIAFLSQGTTLEQGTVIMTGTPSGVGA 179 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 +L+ GD++ IE IGT ++ Sbjct: 180 VSG--RYLKDGDLVEISIEQIGTLSHKI 205 >UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifunctional isomerase : decarboxylase; n=2; Bacillaceae|Rep: 4-hydroxyphenylacetate degradation bifunctional isomerase : decarboxylase - Oceanobacillus iheyensis Length = 263 Score = 121 bits (291), Expect = 2e-26 Identities = 70/197 (35%), Positives = 103/197 (52%) Frame = -3 Query: 627 EEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHA 448 E+ TPP+ P ++ K +T +G TI L V K + L VVIGK A + +A Sbjct: 68 EDPYKTPPKAPILYIKPINTHIGYGMTIPLPEGVEKVSI-GAALGVVIGKPAKNIRKENA 126 Query: 447 FDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCS 268 DYV GYTI D+ + + + KA D FCPIGPW++ D I NP L ++ Sbjct: 127 LDYVAGYTIVNDVSIPNESYYRPAYK---EKARDGFCPIGPWVLRRDAIENPNELGIRVY 183 Query: 267 INGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDV 88 ING KQ++ T+ I + ++ +++ MTL GD++L G P N P + D Sbjct: 184 INGEIKQENTTSNLIRSVEQLMEEVTDFMTLYEGDVLLVGVP------ENAP-IAKENDR 236 Query: 87 ITSEIENIGTFETRVEE 37 + EI+NIGT +VE+ Sbjct: 237 VIIEIDNIGTLVNKVEK 253 >UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Gammaproteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - marine gamma proteobacterium HTCC2143 Length = 223 Score = 120 bits (290), Expect = 2e-26 Identities = 75/210 (35%), Positives = 107/210 (50%), Gaps = 2/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CVG NY DH +E P+ P +F K + V I + D E+E+ V+ Sbjct: 23 KIVCVGRNYADHAKELNNPIPDRPLLFIKPSTAAVDMLLPINIPTDRG-CCHHELEMAVL 81 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 313 IGK++S V S A D ++G + D+ D + K KA D CP+ P+ Sbjct: 82 IGKRSSSVSSVEAKDAIVGVGLGLDLTLRDLQDELKAKGEPWERAKAFDGSCPLSPFSSV 141 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 D + QNLN+ NG +Q NT + + D+IA +S TLLPGDIILTGTP GV Sbjct: 142 GDI--DQQNLNITLLRNGTVQQSGNTRDMLFPVADLIADISRSFTLLPGDIILTGTPAGV 199 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G L PGD IT+++ ++ T T + Sbjct: 200 GP-------LYPGDTITAQLGDLVTVNTTI 222 >UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Ascomycota|Rep: 2-keto-4-pentenoate hydratase - Sclerotinia sclerotiorum 1980 Length = 241 Score = 120 bits (288), Expect = 4e-26 Identities = 70/215 (32%), Positives = 118/215 (54%), Gaps = 5/215 (2%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+C+G NY DH E + P+ PF F K PS+++ PN ++ + E+EL ++ Sbjct: 20 KVVCIGRNYADHITELNNSKPKQPFFFLKPPSSILPPNGGAVIRPK-GVDLHYEVELALI 78 Query: 486 IGKKASKVDSSH---AFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFCPIGPW 322 +GK+ ++ + A+D + Y ++ D+ A + + K L + K DTF P+ Sbjct: 79 MGKQLKNLEPENEKEAYDSIESYAMSIDMTARNAQNEAKKKGLPWDIAKGFDTFLPMSN- 137 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 I++ +I +P N V ++N +QK +T +++IP I++ +S VMTL GDI+LTGTP Sbjct: 138 IISKSQIPDPHNATVWLTVNNEHRQKDSTELMLYRIPRILSDISKVMTLEKGDIVLTGTP 197 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 GVG + P + ++ G + + G E VEE Sbjct: 198 KGVGSVK-PGDVMRVGISVGGKELTEGKIEVAVEE 231 >UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria|Rep: Putative hydratase - Polaromonas naphthalenivorans (strain CJ2) Length = 289 Score = 119 bits (286), Expect = 8e-26 Identities = 76/218 (34%), Positives = 113/218 (51%), Gaps = 10/218 (4%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQK----------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 517 KV+ +NYK H +E + + E +F K S+VVGP+ ++++ + Sbjct: 79 KVIAAPVNYKKHLQEAREQVEIHHNNQVAEIEKIGLFLKATSSVVGPSHGVEIQHP-DRR 137 Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337 E EL VIGK + AFD++ YTI D+ ++ L K++DT+ Sbjct: 138 NDHEAELVAVIGKTGRNIPRERAFDHISAYTIGLDMTVRGPQERS------LRKSIDTYS 191 Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 +GPW+VT+DEI +PQ L+ ++NG ++QK+NT + IP +I S+ TL PGD++ Sbjct: 192 VVGPWLVTADEIDDPQALDFWLTVNGERRQKANTRDLVLDIPALIEMASSYYTLQPGDLL 251 Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TGTP GVG N GD IT EI IG V Sbjct: 252 FTGTPEGVGPVVN-------GDEITVEIAGIGRMNVAV 282 >UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gammaproteobacteria|Rep: Uncharacterized protein ycgM - Escherichia coli (strain K12) Length = 219 Score = 119 bits (286), Expect = 8e-26 Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 2/188 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+CVG NY H +E PE P +F K + + + + D +V E+EL V+ Sbjct: 18 KVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFG-SVHHEVELAVL 76 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAMDTFCPIGPWIVT 313 IG + H + GY +A D+ D + K KK Q KA D CP+ +I Sbjct: 77 IGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPA 136 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 ++ G+PQN + S+NG Q+Q+ T IHKI +IA +S TL GD++LTGTP GV Sbjct: 137 AEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGV 196 Query: 132 GVYRNPPE 109 G ++ E Sbjct: 197 GPLQSGDE 204 >UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Salinibacter ruber DSM 13855|Rep: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Salinibacter ruber (strain DSM 13855) Length = 220 Score = 118 bits (283), Expect = 2e-25 Identities = 61/181 (33%), Positives = 100/181 (55%), Gaps = 2/181 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+LC+G NY DH E P+ P +F K S +V ++L S+ V E+EL V Sbjct: 16 KLLCIGRNYADHAAEMDRAVPDEPMVFLKPASALVRSGGAVRLPPQ-SQDVHHEVELVAV 74 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFCPIGPWIVT 313 +G + + S A D+V GY + D+ A D + K + + K DTF P+GP I Sbjct: 75 VGTEGKNIPRSAALDHVAGYAVGLDMTARDLQAEAKERRHPWSVAKGFDTFAPLGP-IQP 133 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 ++ + + Q+L ++ ++N +Q+++T I + D++ S++ TL PGD++ TGTP GV Sbjct: 134 AEAVDDVQDLTLRLTVNDETRQEASTRHQIFPVRDLVHYCSHIFTLSPGDLLYTGTPSGV 193 Query: 132 G 130 G Sbjct: 194 G 194 >UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer; n=10; Bacteria|Rep: 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer - Synechocystis sp. (strain PCC 6803) Length = 276 Score = 118 bits (283), Expect = 2e-25 Identities = 72/208 (34%), Positives = 101/208 (48%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ VG NY+ H E P P +F K PS + + I S+ V E EL V+ Sbjct: 59 KIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAADQEEIVYPSQ-SQRVDYEGELAVI 117 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK+ + A + GYTIA DI A D ++ SQ K D FCP+GPW+V Sbjct: 118 IGKQVKDITEEEAASAIWGYTIANDITARDLQRQD--SQWTRAKGFDGFCPLGPWVVR-- 173 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 I +L + +Q + + + P +++ +S VMTL PGD+ILTGTP G+ Sbjct: 174 HIDPEAHLETTVNDEETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEGISA 233 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 LQ GD + EIE IG + Sbjct: 234 -------LQVGDKVEVEIEGIGNLTNTI 254 >UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Gammaproteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Enterobacter sp. 638 Length = 219 Score = 118 bits (283), Expect = 2e-25 Identities = 69/181 (38%), Positives = 95/181 (52%), Gaps = 2/181 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+CVG NY H +E P+ P +F K + + + L + +V E+EL V+ Sbjct: 18 KVVCVGSNYAKHIQEMGSAVPDEPVLFIKPETALCDIRQPLALPQGLG-SVHHEVELAVL 76 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAMDTFCPIGPWIVT 313 IG + H + GY IA D+ D + K KK Q K D CPI +I T Sbjct: 77 IGATLRQASEEHVQKAIAGYGIALDLTLRDVQGKMKKAGQPWEKAKGFDNSCPISGFIPT 136 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 +D +PQN ++ +NG +Q+ NT IHKI +IA +S TL PGD+ILTGTP GV Sbjct: 137 ADFKADPQNTSLSLKVNGDIRQQGNTADMIHKILPLIAYMSRYFTLKPGDVILTGTPEGV 196 Query: 132 G 130 G Sbjct: 197 G 197 >UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 343 Score = 117 bits (282), Expect = 2e-25 Identities = 73/188 (38%), Positives = 99/188 (52%), Gaps = 4/188 (2%) Frame = -3 Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418 PF F K S+++GP D + + D S+ + E+EL VVIGK A +V A D+V GY + Sbjct: 137 PFAFLKPFSSILGPFDDLAVPAD-SEQLDWELELGVVIGKPARRVGRDRALDHVAGYVVV 195 Query: 417 QDIGATDWEKNKKISQLLL----GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 DI D + QL L GK+ P+GP IV + + +PQ L + +NG Sbjct: 196 NDISVRDHLYRPDVPQLGLDWVSGKSGPGMLPMGPLIVPAAFVADPQQLMITLKLNGEVM 255 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70 Q +T I I +I S M LLPGDII TG+P G G + FL+PGDV+ IE Sbjct: 256 QHESTADMIFPIARLIEAFSVHMQLLPGDIICTGSPSGNGTHFG--RFLRPGDVMEGTIE 313 Query: 69 NIGTFETR 46 +GT R Sbjct: 314 GLGTQRNR 321 >UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - Pseudomonas abietaniphila Length = 289 Score = 117 bits (281), Expect = 3e-25 Identities = 73/216 (33%), Positives = 111/216 (51%), Gaps = 5/216 (2%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 ++V+ G NY H E L+ P P F K ++G +D I+ ++ + E+EL Sbjct: 70 NRVVVAGANYAKHLVEFGLSAPSQPVAFLKAYGALIGAHDPIRFP-PLTTELDHEVELVA 128 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKISQ-LLLGKAMDTFCPIGPWI 319 VIG + VD VLGYT+ D+ A D +++ K I L K+ D +GPW+ Sbjct: 129 VIG--SDDVDLDDPLACVLGYTVGNDVSARDLQRSGPKGIGMDLFAAKSQDKTTGLGPWV 186 Query: 318 VTSDEI--GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 VT DE+ G+P+ L + +NG +Q NT + ++IA + + GD++ TG+ Sbjct: 187 VTKDELPEGSPK-LRLTLKVNGQMRQDGNTADMTWDVGELIAFVQQRSSFACGDVLFTGS 245 Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 P GVG+ FL PGDV+ + IE IGT V E Sbjct: 246 PAGVGM--GTGIFLDPGDVVEASIEGIGTLRNVVGE 279 >UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Corynebacterium|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 268 Score = 115 bits (276), Expect = 1e-24 Identities = 81/208 (38%), Positives = 107/208 (51%), Gaps = 6/208 (2%) Frame = -3 Query: 666 KVLCVGLNYKDHCEE--QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 KV+ +G NY DH E +K P +F K P+ V GP I++ +K V E EL Sbjct: 62 KVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRIPSFATK-VEFEGELA 120 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 VVIGK V + VLG+TI D+ + D + Q K +DTF PIGPWI T Sbjct: 121 VVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFAD--GQWARAKGIDTFGPIGPWIET 178 Query: 312 SDEIGNPQNLNVKCSI--NGVQ--KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 + NL +K + +G KQ SN+NQ I K+ +II ++ MTLLPGD+I TG+ Sbjct: 179 DINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGS 238 Query: 144 PGGVGVYRNPPEFLQPGDVITSEIENIG 61 P G E + GD I EI IG Sbjct: 239 PAGT-------EAMVDGDYIEIEIPGIG 259 >UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3; Trichocomaceae|Rep: Remark: ORF contains 1 frameshift - Aspergillus niger Length = 296 Score = 115 bits (276), Expect = 1e-24 Identities = 67/215 (31%), Positives = 110/215 (51%), Gaps = 5/215 (2%) Frame = -3 Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL-KMDVSKAVVCEI-E 499 N+ + CVGLNY+ H +E L P P ++ K P+ + P++TI + + S E E Sbjct: 64 NNSIYCVGLNYRSHAKEANLNVPANPPVWTKPPAALASPDETIPISRFCASHLPDWEAGE 123 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFCPIGPW 322 L V ++ V A Y+LGYT+ D+ ++ + Q KA D F PIGP Sbjct: 124 LVFVTSRECRDVTPEQASQYILGYTVGNDLSCRFFQLPEQSGGQFFYAKAFDKFAPIGPV 183 Query: 321 IVTSDEIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPD-IIARLSNVMTLLPGDIILTG 148 +V+ D + + + INGV KQ + + + P+ +++ +S T+ +++TG Sbjct: 184 LVSPDVFAKTRTSATLVTRINGVVKQDTVIGKDMIFSPERVLSWMSQSTTIPAYTVVMTG 243 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TP G GV++ P + L+ GD I EI +GT + V Sbjct: 244 TPAGAGVFQTPRQLLKDGDHIEVEISGLGTLKNVV 278 >UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-containing protein 1; n=21; Eumetazoa|Rep: Fumarylacetoacetate hydrolase domain-containing protein 1 - Homo sapiens (Human) Length = 224 Score = 114 bits (275), Expect = 2e-24 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 2/187 (1%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 ++CVG NY DH E + P +F K PST P + L ++ + E+EL VV+ Sbjct: 20 IVCVGRNYADHVREMRSAVLSEPVLFLK-PSTAYAPEGSPILMPAYTRNLHHELELGVVM 78 Query: 483 GKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVTS 310 GK+ V + A DYV GY + D+ A D E KK L K+ CP+ + V Sbjct: 79 GKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAF-VPK 137 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 ++I +P L + +NG +Q+ T+ I IP II+ +S ++TL GDIILTGTP GVG Sbjct: 138 EKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVG 197 Query: 129 VYRNPPE 109 + E Sbjct: 198 PVKENDE 204 >UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Serratia proteamaculans 568 Length = 287 Score = 113 bits (273), Expect = 3e-24 Identities = 74/220 (33%), Positives = 110/220 (50%), Gaps = 10/220 (4%) Frame = -3 Query: 666 KVLCVGLNYKDHCEE----QKLTPPELPF------IFNKFPSTVVGPNDTIKLKMDVSKA 517 K++ +NY+DH E Q++ ++ +F K S++ GPN+ I L + + Sbjct: 79 KIVAAPINYRDHIAEANADQQINHGKVYTDISEYGLFLKANSSLCGPNEIIPLPIP-GRR 137 Query: 516 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 337 E+EL V+IG++A + A + V GY I D+ E K+ D F Sbjct: 138 TDPEVELAVIIGQRARNLPVDQALEAVFGYAIGIDMTVRGSEFPS------FRKSADGFS 191 Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 +GPWIVT DEIG+P L++ +NG +Q SNT I+ + +IA S + TL PGD+I Sbjct: 192 VLGPWIVTPDEIGDPNTLDLSIRVNGQLRQHSNTRHLIYNVQRLIAYASAMFTLWPGDVI 251 Query: 156 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 TGTP GV +Q GD I IE IG + + Sbjct: 252 YTGTPSGVSA-------IQAGDRIEVSIERIGAMSVTIAD 284 >UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Solibacter usitatus Ellin6076|Rep: Fumarylacetoacetate (FAA) hydrolase - Solibacter usitatus (strain Ellin6076) Length = 252 Score = 113 bits (271), Expect = 5e-24 Identities = 73/209 (34%), Positives = 101/209 (48%), Gaps = 1/209 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+L VGLNYK H + P P +F K S + P D I+L D + V E E+ VV Sbjct: 56 KILAVGLNYKSHLGSRP--QPAHPEMFYKPISALQNPGDPIELPRDATD-VHSEGEMVVV 112 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLLLGKAMDTFCPIGPWIVTS 310 +G A D V G T D+ W+ KK Q K DTF P+GP IV+ Sbjct: 113 VGGYLRNASVDEAADAVFGVTCGNDVSDRSWQHGEKKDLQWWRAKGSDTFAPLGPAIVSG 172 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 + G L ++ ING QK T+ I IP +++ +S +TL PGD++ TGTPG Sbjct: 173 VDYGK---LLLQTRINGETVQKQFTSDLIFDIPTVLSWISGWVTLFPGDLVYTGTPGNT- 228 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 + PGD++ E+E +G V Sbjct: 229 ------RKMSPGDLVEVELEGVGVLSNPV 251 >UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 312 Score = 112 bits (270), Expect = 7e-24 Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 8/218 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPEL-------PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 505 V+C+G+NY +H +E E+ F+K + N I L ++++ + E Sbjct: 98 VICLGINYLEHAKESAAYKNEIFDQKRENAVYFSKRVNYATPHNAPIPLHSNLTQKLDYE 157 Query: 504 IELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 +EL VV+G K + D + GYTI DI + D ++ K Q +GK+++ P+G Sbjct: 158 VELGVVLGSHLYKPKNMQEVIDSIFGYTIINDISSRDIQQKHK--QWYMGKSLEGSLPMG 215 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 P IV++ I + QNL +K +NG +Q S+T+ I I + LS+ L II G Sbjct: 216 PCIVSARSI-DAQNLAIKSYVNGELRQDSHTSLMICNITAALYELSHYCMLQAASIISMG 274 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 34 TP GVG+ NPP FL D I EI++IG+ V ++ Sbjct: 275 TPSGVGMGFNPPRFLSNNDEIVCEIQHIGSLRNVVIDY 312 >UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate (FAA) hydrolase - Sphingomonas wittichii RW1 Length = 329 Score = 112 bits (269), Expect = 9e-24 Identities = 66/190 (34%), Positives = 96/190 (50%), Gaps = 4/190 (2%) Frame = -3 Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418 P++F K +TV G NDT+ L + +K E+EL VVIG+ ++ A ++V GY I Sbjct: 139 PYVFTKPITTVAGANDTLILPANTTKPD-WELELAVVIGRGGIRIPREAAMEHVAGYAIV 197 Query: 417 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 D+ A D L L K + F P GP++V + I +P L ++ S+ G Sbjct: 198 NDVSARDLIPRTDYKLLGTDWLRSKGQEGFLPFGPYMVPARFIADPYALRIRLSVEGQMM 257 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70 Q T + I I +S LLPGD+I TG+P G G + N FLQ GD++ EI+ Sbjct: 258 QDETTADMMFDIARQIEYISRYSRLLPGDVICTGSPAGNGTHYN--RFLQDGDLMIGEID 315 Query: 69 NIGTFETRVE 40 +G R E Sbjct: 316 GLGAQRIRCE 325 >UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep: Isomerase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 224 Score = 111 bits (268), Expect = 1e-23 Identities = 66/181 (36%), Positives = 102/181 (56%), Gaps = 2/181 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ VGLNY H +E P+ P +F K S+ + TI++ + ++ E+EL VV Sbjct: 15 KIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIPHPLD-SLHHEVELAVV 73 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 313 IG+KA V A +Y+ GY +A D+ A + + + S L L K DTF PI ++ Sbjct: 74 IGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLAKGQDTFTPISS-VLP 132 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + +P NL + ++ +QK T I K+P +I+ +S+VMTL GD+ILTGTP G+ Sbjct: 133 KAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFKGDVILTGTPEGI 192 Query: 132 G 130 G Sbjct: 193 G 193 >UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Bacillus coagulans 36D1|Rep: Fumarylacetoacetate (FAA) hydrolase - Bacillus coagulans 36D1 Length = 278 Score = 111 bits (267), Expect = 2e-23 Identities = 79/219 (36%), Positives = 99/219 (45%), Gaps = 6/219 (2%) Frame = -3 Query: 681 VHGNDKVLCVGLNYKDHCEEQKLTPPELP------FIFNKFPSTVVGPNDTIKLKMDVSK 520 V G K+ +NY H EE P +F K P ++ GP D I L + Sbjct: 72 VPGAGKIWAAPVNYLKHQEEMNHQFNNAPRTIEELSLFLKSPQSLSGPTDPIILPFP-ER 130 Query: 519 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 340 E EL ++GKKA V + A DY+ GY DI E+ K+ DTF Sbjct: 131 RTDHEAELGYIVGKKAKNVKAREAKDYIFGYFALLDISIRGNEERT------WRKSFDTF 184 Query: 339 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 160 PIGPWIVT DEI NP +L + +N +Q +T I+ + MTL PGDI Sbjct: 185 TPIGPWIVTEDEIKNPNDLAISLWVNDELRQSGSTKYLIYDCYKCFELACDHMTLHPGDI 244 Query: 159 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 I TGTP GVG R GD + IE IG F V Sbjct: 245 IATGTPEGVGPIRE-------GDRVKISIEQIGEFTVDV 276 >UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Novosphingobium aromaticivorans (strain DSM 12444) Length = 296 Score = 111 bits (266), Expect = 2e-23 Identities = 65/208 (31%), Positives = 108/208 (51%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++CV LNY +E P P F K P T + + ++ + K + E E+ +V Sbjct: 47 KIICVHLNYHSRVQEFITKLPPAPTYFQK-PLTALNTHKGAIVRPERCKWLNYEGEIAIV 105 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IGK + + A DY+LGY++A D G D+ ++ +L K DT CPIGP +VT Sbjct: 106 IGKTCRNISPAEAGDYILGYSVANDYGLHDF-RDTDAGSMLRVKGSDTLCPIGPGLVTGW 164 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + + ++ +NGV KQ+ NT+ + ++A ++ +TL PGD++L+GTP Sbjct: 165 DFRDKM---IRTYVNGVLKQEDNTSNMEWDMHYLVADIARTITLEPGDVLLSGTPAN--- 218 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 P +Q GDV+ E++ +G + Sbjct: 219 -SRP---VQIGDVVEVEVDGLGRLSNTI 242 >UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 255 Score = 111 bits (266), Expect = 2e-23 Identities = 80/208 (38%), Positives = 106/208 (50%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+ +G NY D P P IF K ++VVGP+D I + S AV E EL +V Sbjct: 59 KVVGIGDNYSDTPIPADERPE--PPIFLKANTSVVGPDDPIAIPA-WSNAVAFEGELAIV 115 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 I A V A +LGYTIA D A D S+ GK+ D+ CP+GPWI T D Sbjct: 116 IKSLAKDVSVEDAPQMILGYTIANDATARDAMTGGPWSR---GKSFDSACPLGPWI-TVD 171 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 + NL ++ +NG Q S+T I ++++ LS+ MTLLPGD+I TG P G Sbjct: 172 PALDVTNLAIRSYLNGEIAQDSSTAHMIWNPFELVSYLSHQMTLLPGDVIATGAPAGA-- 229 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRV 43 E + GD + EIE IG+ V Sbjct: 230 -----EIVHAGDRVEIEIEGIGSLTNPV 252 >UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=11; Bradyrhizobiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase - Rhodopseudomonas palustris Length = 233 Score = 110 bits (265), Expect = 3e-23 Identities = 68/210 (32%), Positives = 101/210 (48%), Gaps = 2/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 ++ CVG NY +H E + PF F K V TI ++K + E+EL V Sbjct: 29 RIWCVGRNYLEHVREMGNDERQPPFFFAKHADMVTPDGATIPYP-PLTKDLHHEVELVVA 87 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIVT 313 + + A D+V GY + D+ D + KK +GK+ D P G + Sbjct: 88 LKSGRLNIPVERALDHVWGYAVGIDLTRRDLQIASRKKEQPWEIGKSFDASAPCGA-LRP 146 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + EIG+P + S+NG ++Q + ++ I +P+IIA+LS + L GDII+TGTP GV Sbjct: 147 ASEIGHPATGKIWLSVNGTERQTGDLSEMIWNVPEIIAKLSAQVELAAGDIIMTGTPAGV 206 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 L PGD I I+ IGT + Sbjct: 207 AA-------LSPGDAIACGIDGIGTLNVTI 229 >UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Silicibacter pomeroyi|Rep: Fumarylacetoacetate hydrolase family protein - Silicibacter pomeroyi Length = 281 Score = 110 bits (265), Expect = 3e-23 Identities = 62/211 (29%), Positives = 104/211 (49%), Gaps = 3/211 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFI--FNKFPSTVVGPNDTIKLKMDVS-KAVVCEIEL 496 K+LC G+NY+ + PP+ + F++ P T+VG +++ + ++ E E+ Sbjct: 72 KILCAGMNYRKPYPVAGVAPPDPGHVVLFSRHPQTLVGHGAMLEMPQGAAAESFDFEGEI 131 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 VIG+ + A +VLGY+ + W K+ + GK GPWI Sbjct: 132 VAVIGQPGRHIAPEAALGHVLGYSAMNEGSVRGWMKHS----VHAGKNFHASGSWGPWIT 187 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 T+DE G+ + ++ +NG Q + I + ++IA +S++ L GDII TG+P G Sbjct: 188 TADEAGDIAGMTLETRVNGTPMQSDSGAGMIFGLAELIAYISHIQPLEAGDIIATGSPDG 247 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G R PP FL+ GD + + +GT + V Sbjct: 248 TGGSRTPPAFLRSGDRVAVTVGGVGTLKNTV 278 >UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 325 Score = 110 bits (264), Expect = 4e-23 Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 4/199 (2%) Frame = -3 Query: 627 EEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHA 448 ++ K PP P++F K + G D I L + + + E EL VVIG + + A Sbjct: 121 DQGKQLPPLRPYMFGKI-NVPTGAFDDIILPPGMER-IDWEAELMVVIGTPGLAIRPAEA 178 Query: 447 FDYVLGYTIAQDIGATD--WEKNKKI--SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLN 280 ++ GY D+ D W +++ S L GK+ D+F P+GP + + + +L Sbjct: 179 HRHIAGYMTGNDVSCRDRTWREDRPTIRSDWLGGKSYDSFAPLGPLLTPRQFVPDHADLA 238 Query: 279 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQ 100 ++ +NG KQ N+ I + I S++MTLLPGD+I TGTP G G R EFL+ Sbjct: 239 IRLWVNGELKQDGNSRDMTFGIEEQIEYASSMMTLLPGDVIATGTPAGTGQERG--EFLK 296 Query: 99 PGDVITSEIENIGTFETRV 43 GD++ +E+E+ G RV Sbjct: 297 EGDIVETEVESCGRQRNRV 315 >UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; Eurotiomycetidae|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 327 Score = 109 bits (262), Expect = 6e-23 Identities = 65/210 (30%), Positives = 108/210 (51%), Gaps = 3/210 (1%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVV 487 ++CVGLNY++H E L P P ++ K P + P+ I + K+ E ELT+V Sbjct: 119 IICVGLNYRNHANEASLPIPTCPPMWYKAPPALADPDSEIPVPPQAQKSFPDFEGELTIV 178 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 + + +S A ++LGYTI D+ A +++ Q K D F P+GP +V Sbjct: 179 LRNTIKSISASEATSHILGYTIGNDLTARFFQRACG-GQYTHAKGFDNFAPLGPRLV-HP 236 Query: 306 EIGNPQNLN--VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + +P + + + +NG Q S + FI + ++++ LS T+ G I+TGTP GV Sbjct: 237 SVFSPSDASRRITTRVNGRVVQDSPFD-FIFPVDELVSFLSEGTTIPAGTAIMTGTPAGV 295 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G +++P LQ GD + E++ IG + Sbjct: 296 GWFQDPKCPLQHGDAVEVEVQPIGVLRNTI 325 >UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the fumarylacetoacetate hydrolase family; n=6; Bifidobacterium|Rep: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the fumarylacetoacetate hydrolase family - Bifidobacterium longum Length = 292 Score = 109 bits (261), Expect = 8e-23 Identities = 69/184 (37%), Positives = 96/184 (52%), Gaps = 2/184 (1%) Frame = -3 Query: 606 PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGY 427 PE IF K ++V+GP+D I SK + E E+ VV+G+ A V +A DYVLG+ Sbjct: 111 PEDMVIFTKPSTSVIGPDDPIVYPA-CSKDMNFEPEVAVVMGRIAKNVTVENAMDYVLGF 169 Query: 426 TIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSING--VQ 253 T D+ D + K DT CP+GPWIV D++ + ++ + ++NG V Sbjct: 170 TCVNDVTLRDLQGIDPT--WTRAKGFDTSCPLGPWIVMRDDL-DWKDAKISFTLNGEDVP 226 Query: 252 KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 73 T IH IP+ IA +S+ TLLPGD+I+TGTP G L PGD + Sbjct: 227 MASGTTANLIHGIPEQIAAISSFSTLLPGDVIMTGTPNASG-------HLDPGDETIVHV 279 Query: 72 ENIG 61 E IG Sbjct: 280 EGIG 283 >UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=123; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 109 bits (261), Expect = 8e-23 Identities = 69/208 (33%), Positives = 103/208 (49%), Gaps = 3/208 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +V CVG NY DH E P E PF F K +V + T+ ++ + EIEL V Sbjct: 47 RVFCVGRNYADHAREMGADPDREPPFFFTKPADAIVPASGTVAYP-PLTNDLHHEIELVV 105 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAMDTFCPIGPWIV 316 IGK +D + A +V GY + D+ D + KK+S+ K D P+ + Sbjct: 106 AIGKDGRAIDPADALSHVWGYGVGIDLTRRDLQAEAKKLSRPWDWAKGFDASGPVTA-LR 164 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 + G+P + ++NG +Q+ + I +PD+IA +S + L GD+I TGTP G Sbjct: 165 AASATGHPATGRIWLAVNGDTRQQGDLADMIWAVPDVIAYVSRSVELKAGDLIFTGTPAG 224 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFE 52 VG LQPGD +T ++ + TFE Sbjct: 225 VGA-------LQPGDRVTGGVDGVATFE 245 >UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Jannaschia sp. CCS1|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Jannaschia sp. (strain CCS1) Length = 271 Score = 109 bits (261), Expect = 8e-23 Identities = 70/215 (32%), Positives = 106/215 (49%), Gaps = 7/215 (3%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+LCV LNY DH +E PE P +F K ++ I+ +++ + E EL ++ Sbjct: 59 KILCVALNYVDHAKEANQPVPETPIVFFKTFDAMIAGGAPIRAPRMITQ-LDYEGELALI 117 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK--ISQL--LLGKAMDTFCPIGPWI 319 IGK+ + + A+D++ G T D+ A D K K S L GK ++ PIGP + Sbjct: 118 IGKRGFDIAKTDAWDHIAGVTTLNDVSARDIFKVKAGAASHLDWFSGKCLNQSTPIGPEV 177 Query: 318 VTSDEIGNPQNLN---VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 I + ++C +NG +Q + I IP +IA +S+ + L PGDII TG Sbjct: 178 FPLSAIEDDLKAGTTRIRCLVNGEVRQDAPVADMIFDIPTMIAFISSRIPLNPGDIIATG 237 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TP GVG +L GDV+ E+ + E V Sbjct: 238 TPPGVGA--GTDRYLSKGDVVRVEVTGLPPMENTV 270 >UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Comamonas testosteroni KF-1 Length = 289 Score = 109 bits (261), Expect = 8e-23 Identities = 63/183 (34%), Positives = 96/183 (52%), Gaps = 5/183 (2%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG--PNDTIKLKMD-VSKAVVCEIEL 496 ++ CVG NY+DH +E T E PF F K V T ++ +++ + EIEL Sbjct: 84 RIYCVGRNYEDHAKEMGFTGREPPFFFMKPADATVALEAGSTGQVAYPTLTQNLHHEIEL 143 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPW 322 V IGK + ++ A Y+ GY + D+ D E K+ +GKA + PIGP Sbjct: 144 VVAIGKAGKNIKAADALQYIYGYAVGLDMTRRDLQNEMKKQGRPWCIGKAFEQSAPIGP- 202 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 I +D+ G+ N + +NG +Q+S+ ++ I I + I LS+ L PGD+I+TGTP Sbjct: 203 ITPADQAGDIANAEISLQVNGDYRQRSHIHKLIWNIAETIEHLSSAWELQPGDLIMTGTP 262 Query: 141 GGV 133 GV Sbjct: 263 EGV 265 >UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella pertussis|Rep: Putative hydrolase - Bordetella pertussis Length = 316 Score = 108 bits (259), Expect = 1e-22 Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 5/192 (2%) Frame = -3 Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGY 427 ++P F K S V+ P+D+ + A E+E+ V+G A ++V GY Sbjct: 126 DMPAGFIKIAS-VMTPHDSAVARPCGVLAFDYEVEVAAVLGGPVPLGTPPERALEHVFGY 184 Query: 426 TIAQDIGATDWEKNKKISQLL-LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 T+ D+ A +W + + +Q++ +GK P+GPWIVT+DE+ +P L + S+NG + Sbjct: 185 TLFNDLSAREWARAEMKNQMIAMGKNFPGAGPLGPWIVTADEVPDPAQLELSLSVNGEPR 244 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP---PEFLQPGDVITS 79 Q + + I +IA S + L G++I +GTP G + R P P FL+PGD++ + Sbjct: 245 QHGSCKEMIFTFAQLIAHWSRI-GLGAGELIASGTPEGGAISRKPDPAPFFLKPGDIVEA 303 Query: 78 EIENIGTFETRV 43 IGT TR+ Sbjct: 304 HCPQIGTLRTRI 315 >UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=3; Burkholderiales|Rep: 2-Keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 301 Score = 108 bits (259), Expect = 1e-22 Identities = 60/163 (36%), Positives = 92/163 (56%), Gaps = 7/163 (4%) Frame = -3 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL------LG-KAM 349 E EL VVIGK + A D V GYTIA D+ A D + +++ +G K Sbjct: 141 EAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNLRREQVDASSPFRFDWIGHKCF 200 Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169 + CP+GP++ + + +P+ L++K +N KQ SNT+ ++ + + IA LS +TL P Sbjct: 201 EGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSNHLYTVAEQIAYLSERLTLYP 260 Query: 168 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 GD++LTGTP GVG+ FL+ GD I I+ +G ET ++ Sbjct: 261 GDVLLTGTPAGVGM--ESGVFLKRGDSIRVWIDGLGELETSLQ 301 >UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG10641.1 - Gibberella zeae PH-1 Length = 230 Score = 107 bits (258), Expect = 2e-22 Identities = 62/151 (41%), Positives = 81/151 (53%), Gaps = 1/151 (0%) Frame = -3 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E EL VVIG+ A V A +YVLGYT A DI + + + SQ K D CP+G Sbjct: 73 EAELAVVIGRAAKNVTKEEAMEYVLGYTAANDISSRTSQFGQ--SQWCFSKGFDGSCPLG 130 Query: 327 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 P +V+ D + +P N++ Q + I IP +I+ LS TLLPG +ILTG Sbjct: 131 PALVSKDLVPDPSMFNIRGLKKDQVLQDCGADDLIFDIPTLISFLSQGTTLLPGTVILTG 190 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEI-ENIGT 58 TP GVGV R P + GD + EI +IGT Sbjct: 191 TPAGVGVGRQPKVTISDGDEFSVEILPHIGT 221 >UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; Alphaproteobacteria|Rep: Possible isomerase/decarboxylase - Rhodopseudomonas palustris Length = 329 Score = 107 bits (257), Expect = 2e-22 Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 2/187 (1%) Frame = -3 Query: 594 FIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQ 415 +I N+F +V G N +K S + E+E ++ +K + + ++ A +++ GYTI Sbjct: 143 YITNRF--SVRGTNTVVKWPR-YSAVMDYELEFGIITKRKGANISAAQAKNHIFGYTIFN 199 Query: 414 DIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKS 241 D A D ++ + +L GK+ D IGPWIVT DEIG+P LN++ +NG + + Sbjct: 200 DFSARDAQRIEMEGRLGPAKGKSFDGGNVIGPWIVTPDEIGDPYRLNMEARVNGEVRSRG 259 Query: 240 NTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 61 T + +IIA +S TL+PG+ I +GT G G FL+ GDVI E+E IG Sbjct: 260 VTEGMLFSFEEIIAHVSRDETLMPGEFIGSGTVGN-GCGLELGWFLEHGDVIELEVEKIG 318 Query: 60 TFETRVE 40 + +VE Sbjct: 319 IPKNKVE 325 >UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep: ENSANGP00000019097 - Anopheles gambiae str. PEST Length = 232 Score = 106 bits (255), Expect = 4e-22 Identities = 64/188 (34%), Positives = 97/188 (51%), Gaps = 5/188 (2%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT---IKLKMDVSKAVVCEIEL 496 K++ G+NYK+ P+ P IF K S G T I++ + E EL Sbjct: 24 KIIGAGVNYKEILRLTNSPKPDAPVIFFKPISGSTGSTGTPPTIRIPRVFGGVINFEAEL 83 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPW 322 V+IG++ + V + A YV GY +A D+ D+ + + L LGK DT P+ Sbjct: 84 GVIIGRRCANVPTDQAMAYVGGYCLALDMTGMDFILDARPKGLPWCLGKGFDTSTPVSAL 143 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 + +D + NP ++ V C +NGV+KQ +T I I ++IA +S MTL D++LTGTP Sbjct: 144 VQRAD-LPNPDDVRVWCEVNGVRKQDDSTRNLIFPIAELIAYVSRFMTLEENDLLLTGTP 202 Query: 141 GGVGVYRN 118 G G R+ Sbjct: 203 AGAGPVRH 210 >UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Ralstonia pickettii|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Ralstonia pickettii 12J Length = 250 Score = 106 bits (254), Expect = 6e-22 Identities = 63/187 (33%), Positives = 96/187 (51%) Frame = -3 Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430 PP+ P ++ K +T +G + L DV V L V I A++V + HA D++ G Sbjct: 64 PPKAPILYLKPANTRIGHGHEVALPADVD-GVWAGACLGVAISCTATRVPAQHAADFIAG 122 Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 YTI D+ + + K D FCP+GPW+V D++ N L++ ING K Sbjct: 123 YTIVNDLTVPHASYYRPA---IRHKCRDGFCPMGPWMVDRDDVPNADALDITVRINGEVK 179 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70 Q++NT+ + I ++A ++ MTL GD++L G P NPP + GD I +I Sbjct: 180 QRANTSTLVRPIAQLLADVTAFMTLESGDVLLVGMP------ENPP-LARAGDRIDIDIA 232 Query: 69 NIGTFET 49 +IGT T Sbjct: 233 HIGTLTT 239 >UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Thermosinus carboxydivorans Nor1|Rep: Fumarylacetoacetate (FAA) hydrolase - Thermosinus carboxydivorans Nor1 Length = 295 Score = 105 bits (252), Expect = 1e-21 Identities = 65/181 (35%), Positives = 92/181 (50%), Gaps = 1/181 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPEL-PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 K+ +GLNY DH + P L P F KF +T++GP + IK+ + S+ E EL + Sbjct: 88 KIWGIGLNYVDHAGDLAEKAPTLAPASFAKFDTTIIGPGEEIKIPLQ-SEKTTGESELAI 146 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 + GKK V+ + V G+T D+ A D + L K DTF GP +VT Sbjct: 147 IFGKKCKDVEEKDWLNVVAGFTTIIDMTAEDILRINP-RYLTRAKNFDTFLSFGPVLVTP 205 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 DEI + LNV ING ++ + +++ S V T+LPGDIILTGTP V Sbjct: 206 DEIEDVNKLNVATVINGRIHARNVVSNMTFPPAYLVSFHSKVATMLPGDIILTGTPRAVQ 265 Query: 129 V 127 + Sbjct: 266 I 266 >UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Mycobacterium sp. JLS|Rep: Fumarylacetoacetate (FAA) hydrolase - Mycobacterium sp. (strain JLS) Length = 265 Score = 104 bits (250), Expect = 2e-21 Identities = 69/213 (32%), Positives = 105/213 (49%), Gaps = 4/213 (1%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 V+ VG+NY H E+ +T P+ F K + ++G D + + +++ + E+EL VV Sbjct: 54 VVGVGMNYWSHLEKLGVTERPKSTLGFLKPRAAIIGHGDVLANPV-ITEQLDFEVELVVV 112 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG-KAMDTFCPIGPWIVTS 310 + + S + VLGYT+ D+ A D L KA+ P+GPWI T Sbjct: 113 LAQSVSH-PGGRPTEAVLGYTVGNDVSARDAAVPMSGGLDLFSIKALGGTTPVGPWITTK 171 Query: 309 DEIGNPQNLNVKCS--INGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 DE G ++V S +NG Q+Q T + I I + + + M L GDI+ TGT G Sbjct: 172 DEFGGSGQIDVGISLRVNGEQRQHDRTGKMIFSIDECLDYVVARMPLAAGDIVFTGTTHG 231 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 37 VG +LQ GDV+ +E+E +G V E Sbjct: 232 VGF--EDGRYLQAGDVVEAEVEGVGVLRNIVGE 262 >UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2; probable 5- oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2; n=1; Natronomonas pharaonis DSM 2160|Rep: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2; probable 5- oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 319 Score = 104 bits (249), Expect = 2e-21 Identities = 58/188 (30%), Positives = 99/188 (52%), Gaps = 1/188 (0%) Frame = -3 Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424 E+P + +VV P +T++ S + E+EL VIGK+ + + A +Y+ GYT Sbjct: 135 EMPVYYKSTADSVVAPGETVEWPA-YSSLMDYELELAAVIGKEGRDIPAEAADEYIAGYT 193 Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 244 I D A D + + ++L K D GP++VT+D+ +P+ ++ ++NG + Sbjct: 194 IFNDFSARDIQGEEMQARLGPAKGKDFANAFGPYLVTADDF-DPETAEMRATVNGEVWSE 252 Query: 243 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVITSEIEN 67 + H DI+A +S TL PGD++ +GT G G G+ +FL+ GD ++ ++ Sbjct: 253 GTPGEMYHTFADIVAHVSQSETLYPGDVLGSGTVGEGCGLELG--QFLESGDTVSLFVDG 310 Query: 66 IGTFETRV 43 IGT E V Sbjct: 311 IGTLENTV 318 >UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 295 Score = 103 bits (248), Expect = 3e-21 Identities = 65/211 (30%), Positives = 104/211 (49%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ V L Y+ EE P P F K P+ + G ++ ++ + E EL V+ Sbjct: 57 KIIAVHLTYRSRVEEYGARVPPEPSYFLKPPTALNGHRGVVRWPAG-TRFLNYEGELAVI 115 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +G++ V A V GYT A D+G D+ + S L + K D F P+GP +V + Sbjct: 116 VGRRMKGVGMEEALSCVAGYTCANDVGLHDFRHADRGSMLRV-KGQDGFLPLGPEVVPAS 174 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 +P++ ++ +NG Q+ + + +A L ++TL PGD++LTGTP Sbjct: 175 RF-DPEDFALRTYLNGEVVQEGGAEDLLFGVAYQLADLCRLITLEPGDVVLTGTPAN--- 230 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 34 P ++PGDV+ EIE IG VEE+ Sbjct: 231 -SRP---MRPGDVVEVEIEGIGRLSNTVEEW 257 >UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Arthrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase - Arthrobacter sp. (strain FB24) Length = 277 Score = 103 bits (248), Expect = 3e-21 Identities = 65/187 (34%), Positives = 101/187 (54%) Frame = -3 Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418 P F+K ++VVGP D I+L V V E ELT+VIG+KA + +A VLG+TI Sbjct: 102 PQAFHKAATSVVGPGDAIELAPGVGH-VDPEAELTIVIGRKARGLTLENARGAVLGFTIG 160 Query: 417 QDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSN 238 D+ A + +K+ ++ + K+ DTF P GPWIVT + L++ NG + + ++ Sbjct: 161 NDVTARELQKSDEL--WISAKSQDTFTPAGPWIVTGLDTA---ALSIGIVHNGSELRAAS 215 Query: 237 TNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 58 + K+ +I+ L++ MTL PGD++LTG P L PGD +T ++ IG Sbjct: 216 SADLGWKVDEILVYLTSFMTLHPGDLVLTGFPA-------ESARLHPGDTVTCRVQGIGE 268 Query: 57 FETRVEE 37 V + Sbjct: 269 LTNPVSD 275 >UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Aeropyrum pernix|Rep: Fumarylacetoacetate hydrolase family protein - Aeropyrum pernix Length = 286 Score = 103 bits (248), Expect = 3e-21 Identities = 64/204 (31%), Positives = 106/204 (51%) Frame = -3 Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475 VG +Y +H E ++ ++ F F+K +++ G + + + VS+ E E+ ++IGK+ Sbjct: 82 VGRSYAEHAREMGMSK-QIAF-FSKPVTSLTGHLNPVVVP-PVSEKPDYEGEIVIIIGKR 138 Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 295 ++ A + GYT DI TD +S + K +DT+ P+GP D + Sbjct: 139 IKNASTAEAGKAIAGYTAGADI--TDRLLQDMMSWSM-AKGLDTYGPVGPVATIIDSPDD 195 Query: 294 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115 L V +NG + Q+ T I IPD+++RLS + TL PGDI+ TGTP GVG R P Sbjct: 196 LDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGTPPGVGHARKP 255 Query: 114 PEFLQPGDVITSEIENIGTFETRV 43 P +L+ GD + + + ++ Sbjct: 256 PRYLRHGDELEVRVSGLPPLRNQI 279 >UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium japonicum|Rep: Blr7583 protein - Bradyrhizobium japonicum Length = 261 Score = 103 bits (246), Expect = 5e-21 Identities = 66/210 (31%), Positives = 98/210 (46%), Gaps = 6/210 (2%) Frame = -3 Query: 657 CVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496 CVGLNY H +E + P+ P I + + ++ ++ + + + + E EL Sbjct: 58 CVGLNYLKHLKEAADKRGEVPAVPDRPEIGYRAQNALIAHDEEVVIPSFATDKIHYEGEL 117 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 316 VVIGKK + +A D V GYTI D+ W+K + L K DTF P+GPWI Sbjct: 118 VVVIGKKVKHLTKQNAMDCVFGYTIGNDVSERSWQKADR--SLWRSKNADTFKPMGPWIE 175 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 T N + +NG + + TN I + + L+ TL PGD+I GT G Sbjct: 176 TE---ANLARMETVVRVNGKETNRFYTNDMIFGVVPFLVELTKYFTLWPGDVIWMGTDGA 232 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETR 46 P+ ++ GDV+ +I IGT R Sbjct: 233 ------SPD-IKHGDVVEIDITGIGTLRNR 255 >UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=1; Schizosaccharomyces pombe|Rep: Uncharacterized hydrolase C21C3.09c - Schizosaccharomyces pombe (Fission yeast) Length = 221 Score = 103 bits (246), Expect = 5e-21 Identities = 67/202 (33%), Positives = 107/202 (52%), Gaps = 4/202 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKMDVSKAVVCEIELTV 490 KV+C+G NY H E P PF F K S +V P + + + DVS E+ L + Sbjct: 7 KVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELGLIM 66 Query: 489 VIGKKASKVDSSHAF-DYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 319 A + SS+++ D + Y + D+ A + + K L K DTF P+GP I Sbjct: 67 KDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGP-I 125 Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 + I +P N+ ++ S+NG QK +T+ ++KIP I + ++ M+L PGD++LTGTP Sbjct: 126 IPKHLIPDPHNVILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVLTGTPK 185 Query: 138 GVGVYRNPPEFLQPGDVITSEI 73 GVG + PGD++++ + Sbjct: 186 GVGP-------VVPGDILSARL 200 >UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP02096p - Drosophila melanogaster (Fruit fly) Length = 236 Score = 102 bits (245), Expect = 7e-21 Identities = 71/211 (33%), Positives = 105/211 (49%), Gaps = 2/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++ V LNY D + + P+ P +F K S+ + I L +K V E+EL VV Sbjct: 33 KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPIVLPKVFTK-VAYEVELGVV 91 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 313 IGK V + A YV GY +A D+ A + + LGK DT P+ +I Sbjct: 92 IGKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFIPI 151 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 +++ +P NL + ++NG KQ T I K+PDII+ +S MTL D+ILTGTP G Sbjct: 152 -EKVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGA 210 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 ++ GDVI + ++ +VE Sbjct: 211 DAFK-------AGDVIQCGMADLAKLTFQVE 234 >UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase family protein; n=1; Tetrahymena thermophila SB210|Rep: fumarylacetoacetate hydrolase family protein - Tetrahymena thermophila SB210 Length = 218 Score = 101 bits (243), Expect = 1e-20 Identities = 68/181 (37%), Positives = 92/181 (50%), Gaps = 4/181 (2%) Frame = -3 Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 N K+L + NY QK P + P IF K S+++ + + L + EIEL Sbjct: 13 NPKILALAQNYIP--PGQKDVPAQ-PLIFTKPHSSILYKGENLILNS--KNQINYEIELG 67 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ----LLLGKAMDTFCPIGP 325 V+IGK + AFDY+ GY + D+ TDW+ K + +GK D F PI Sbjct: 68 VMIGKSGKNIAKQQAFDYIGGYFLCLDM--TDWDMQKANRKNGFPWDIGKGQDGFLPISD 125 Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 +I D I +P N+N+K IN + NT KI DII +S MTL PGD+ILTGT Sbjct: 126 FIEKKD-IKDPHNINLKLQINQKSEVDDNTKNMYFKIDDIIQYVSQYMTLNPGDLILTGT 184 Query: 144 P 142 P Sbjct: 185 P 185 >UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep: MelH protein - Melittangium lichenicola Length = 329 Score = 101 bits (243), Expect = 1e-20 Identities = 63/192 (32%), Positives = 100/192 (52%), Gaps = 7/192 (3%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 V+C G NY+ H E P F F K S++ + I +K + + + EIEL + Sbjct: 74 VVCQGQNYRSHMLEVGQDPEAKNFNQFFRKASSSLTSGHGDI-VKPERVRMLDYEIELGL 132 Query: 489 VIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 319 VIG+ S +V+ ++V G I D+ A D + + Q K+ TFCP GP++ Sbjct: 133 VIGRPLSGPCRVERERLHEFVAGLVICNDVSARDIQLAE--GQWYKSKSFRTFCPAGPYL 190 Query: 318 VTSDEIGNPQNLNVKC--SINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 D N + +N+K S+N +Q SNT++ ++ + ++ LS VM L PGD+++TGT Sbjct: 191 YLLDAEDNARVMNLKLHLSVNDQTRQDSNTSEMVYPPEETLSELSEVMDLFPGDLVMTGT 250 Query: 144 PGGVGVYRNPPE 109 P GV N P+ Sbjct: 251 PRGVAAGHNAPK 262 >UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family protein; n=25; Enterobacteriaceae|Rep: Fumarylacetoacetate hydrolase family protein - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 218 Score = 101 bits (242), Expect = 2e-20 Identities = 69/211 (32%), Positives = 103/211 (48%), Gaps = 2/211 (0%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +KV+CVG NY +H +E P P +F K + + + + ++ +V E+EL V Sbjct: 17 NKVVCVGSNYSEHIKEMGSATPSEPVLFIKPETALCDLRQPVAIPKNLG-SVHHEVELAV 75 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAMDTFCPIGPWIV 316 +IG + + + GY +A D+ D + KK Q KA D CPI +I Sbjct: 76 LIGTPLKQANEERVARAIAGYGVALDLTLRDLQSEFKKAGQPWEKAKAFDGSCPISGFIP 135 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 + E G+PQ + +N +Q+ NT I I +IA +S TL GDIILTGTP G Sbjct: 136 VA-EFGDPQQTELGVKVNDEVRQQGNTRDMITSILPLIAYMSRFFTLRAGDIILTGTPKG 194 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 VG + GD++T + N T TR+ Sbjct: 195 VGP-------ILSGDMLTITV-NDRTLSTRI 217 >UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=8; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Silicibacter sp. (strain TM1040) Length = 256 Score = 101 bits (242), Expect = 2e-20 Identities = 65/182 (35%), Positives = 93/182 (51%), Gaps = 3/182 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +V C+G NY H E P E PF F K P ++ M S+ V E EL V Sbjct: 55 RVYCIGRNYAAHAVEMGHDPDREPPFFFQKTPDSLDASGRFPYPVM--SEDVHHEAELLV 112 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK-NKKISQLL-LGKAMDTFCPIGPWIV 316 +GK + A D+V GY +A D+ D + KK + +GK+ + P+ P + Sbjct: 113 ALGKGGENISEDAALDHVWGYGLALDMTRRDLQGIAKKAGRPWEIGKSFEHAAPVAP-LT 171 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 + IG+P + ++NG +Q+ + NQ I KIP++IA LS L GD+ILTGTP G Sbjct: 172 PATTIGHPDAGVMTLTVNGTPRQQGDLNQMIWKIPEMIAHLSQYYRLAAGDVILTGTPAG 231 Query: 135 VG 130 VG Sbjct: 232 VG 233 >UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Caulobacter sp. K31|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Caulobacter sp. K31 Length = 293 Score = 101 bits (242), Expect = 2e-20 Identities = 63/204 (30%), Positives = 98/204 (48%), Gaps = 1/204 (0%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 DK++ +G Y H E K P +F + P ++V N I + + S + E EL V Sbjct: 78 DKIIGLGKTYMKHVAEMKAESSSFPGMFLRVPDSLVAHNQPI-WRPEASDTLDYEGELMV 136 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIG+ + +A +V GY D + N S + GK GP IVT+ Sbjct: 137 VIGQGGRMISRENALKHVAGYACHNDGSVRAY--NYIPSAVTAGKNFLNTGGFGPEIVTA 194 Query: 309 DEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 DE+ + L + +NG +Q ++ + + ++ +S + TL PGD+I TGTP G Sbjct: 195 DELPPGCKGLRLTTHVNGDLRQSADVAELHWDVAHLVHLMSTIFTLYPGDLIATGTPSGC 254 Query: 132 GVYRNPPEFLQPGDVITSEIENIG 61 P++L PGDV+ EIE +G Sbjct: 255 AAASANPQWLVPGDVVRVEIEGVG 278 >UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase; n=8; Pseudomonas|Rep: 4-hydroxyphenylacetate degradation; 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase - Pseudomonas entomophila (strain L48) Length = 224 Score = 100 bits (240), Expect = 3e-20 Identities = 59/184 (32%), Positives = 95/184 (51%), Gaps = 1/184 (0%) Frame = -3 Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430 PP P +F K P+T + V K + L VV+G+ AS+V + +A ++V G Sbjct: 39 PPVKPVLFIKTPNTRNSHGQAVTYPAAV-KRLQPGPALGVVMGRDASRVSAENALEHVAG 97 Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 YTI + + + + K D FCP+GP +V + ++ NP L ++ +NG + Sbjct: 98 YTIVNEFSLPE---DSYYRPAVKAKCRDGFCPLGPQLVPAAQVANPDALGIRLWVNGELR 154 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP-GGVGVYRNPPEFLQPGDVITSEI 73 Q +NT + + +IA +S MTL GD+++TGTP G + V PGD +T EI Sbjct: 155 QHNNTANCVRSVAQLIAEISEFMTLHAGDVLITGTPEGRIDVL--------PGDRVTVEI 206 Query: 72 ENIG 61 + +G Sbjct: 207 DGLG 210 >UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 313 Score = 100 bits (240), Expect = 3e-20 Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%) Frame = -3 Query: 606 PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGY 427 P +P +F K ST+ GP I + V++ E+EL VV+G+ V A D +LGY Sbjct: 108 PVIPILFYKPISTLSGPGRDIVIPPCVAEQADYEVELVVVLGRDIKDVSPVEAMDAILGY 167 Query: 426 TIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE---IGNPQNLNVKCSINGV 256 T++ D+ A + + Q LGK+ D + PIGP +V++ I N N+++ +N Sbjct: 168 TLSNDVSAR--TRMFAVPQWGLGKSFDGWLPIGPCLVSASNPRGITNRDNIHLTTKLNNR 225 Query: 255 QKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVI 85 Q NT+ + K + +A LS TL G +++ GTP G G R P L GD + Sbjct: 226 IMQDGNTSDMLWKTAETLAELSKGTTLEAGSLLIMGTPPGEGFKRQPKVCLNHGDTL 282 >UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 255 Score = 98.3 bits (234), Expect = 2e-19 Identities = 60/197 (30%), Positives = 99/197 (50%), Gaps = 3/197 (1%) Frame = -3 Query: 621 QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVVIGKKASKVDSSHAF 445 QKLT P P ++ K +++ PN+ I + ++++ E EL V ++ V S A Sbjct: 57 QKLTIPSNPPLWTKPAASLAHPNEEIPINDFCARSLPDYEGELVFVTSEECKDVTESQAK 116 Query: 444 DYVLGYTIAQDIGATDWEKNKKIS-QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCS 268 DY+LGYTI D+ ++ +S Q KA D F PI P +++ + + + Sbjct: 117 DYILGYTIGNDLTCRMFQLPGNMSGQFFFAKAFDHFAPIDPVLISPKLFESVKRNGLTLK 176 Query: 267 INGVQKQKSNT-NQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGD 91 +NG +QK++ N I I++ +S T+ G ++TGT GVG +R P FLQ GD Sbjct: 177 VNGEVRQKADLHNDMIFSPERILSHMSQGTTIPAGTAVMTGTCEGVGAFRKPKVFLQQGD 236 Query: 90 VITSEIENIGTFETRVE 40 V+ + GT ++ Sbjct: 237 VVEVSMPLAGTLRNTIK 253 >UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA) hydrolase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 349 Score = 97.9 bits (233), Expect = 2e-19 Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 4/183 (2%) Frame = -3 Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418 P++F P+ + GP D + L + + E+E VIG+ V A D V GYTIA Sbjct: 145 PYLFLGSPTALCGPYDDVVLPAEGDQHD-WELEFAAVIGRSGRHVPPERALDLVAGYTIA 203 Query: 417 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 DI D + + L K TF P GP+IV + +G+ L + +NG Sbjct: 204 NDITTRDLVYRPDLKAIGTDWLRSKNAPTFLPTGPYIVPKEFVGDTSGLRITLRLNGETM 263 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70 Q + + I + +++ S+ + L PGD+ILTG+P G G Y FL GDV+ + Sbjct: 264 QDESASDMIFDVARLVSYASSRVLLRPGDLILTGSPAGNGSYWG--RFLGEGDVMEGTVT 321 Query: 69 NIG 61 +G Sbjct: 322 GLG 324 >UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - Pseudomonas abietaniphila Length = 336 Score = 97.5 bits (232), Expect = 3e-19 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 2/176 (1%) Frame = -3 Query: 585 NKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIG 406 N+F V+G +D L SKA+ E+E IGKK + +A D+++G+TI D+ Sbjct: 147 NRF--AVIGADDEF-LWPAFSKALDFELEFGCYIGKKGKDISRDNARDHIVGFTIFNDMS 203 Query: 405 ATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTN 232 A D + + L K DT +GP +VT+DE+G+P +LN+ +NG + + NT Sbjct: 204 ARDAQAAEMPGMLGPAKSKDFDTANIMGPCLVTADELGDPYDLNMVARVNGEEWGRGNTR 263 Query: 231 QFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 64 + D+IA +S TL PG+ + +GT G G +L+PGD + E++ I Sbjct: 264 DMRWRFEDVIAHISRSETLYPGEFLGSGTVGN-GCGLEQLRYLKPGDRVELEVDGI 318 >UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Jannaschia sp. (strain CCS1) Length = 305 Score = 96.7 bits (230), Expect = 5e-19 Identities = 59/191 (30%), Positives = 95/191 (49%), Gaps = 2/191 (1%) Frame = -3 Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424 E P + + +G T++ S + E+EL ++IGK+ + + A +++ GYT Sbjct: 115 EQPIYYKGNRMSFIGHGQTVRWPA-YSDYLDLELELAIIIGKEGADIPRETAHEHIWGYT 173 Query: 423 IAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 I D+ A D + + QL GK DT +GPWIVT+DE+ +P LN+ S+NG + Sbjct: 174 ILNDVSARDAQMREMAGQLGPAKGKDFDTGNILGPWIVTADEVSHPAVLNMDVSVNGERW 233 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70 + IIA +S L PG++I +GT G G + L GD++ IE Sbjct: 234 GGGTSADMQFDFAQIIAHISASERLFPGEVIGSGTV-GTGCGLEIGKRLSDGDMMDLTIE 292 Query: 69 NIGTFETRVEE 37 IGT +++ Sbjct: 293 KIGTLTNTIKK 303 >UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Fumarylacetoacetate (FAA) hydrolase - Halorubrum lacusprofundi ATCC 49239 Length = 273 Score = 95.9 bits (228), Expect = 8e-19 Identities = 65/210 (30%), Positives = 106/210 (50%), Gaps = 2/210 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-SKAVVCEIELTV 490 K+ +GLNY +H + P+ P F K S + GP+ I+L + S+ V E EL V Sbjct: 72 KLWGIGLNYAEHAGDLDEQRPDEPASFMKPSSVLTGPSGPIRLPPESQSERVTAEAELAV 131 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKAMDTFCPIGPWIVT 313 V+G+ V+ + D V G+ D+ A D ++N + L K+ DTF G + Sbjct: 132 VMGRTCRNVEEAAFEDVVAGFLPVIDMTAEDVLQRNPRF--LTRSKSYDTFLVPGAALAV 189 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 +E + L+V+ +NG + ++ + +I++ S+VMTL PGD+ TGTPG Sbjct: 190 PEEPLDLDALSVQTEVNGEIEAENEIRNMLFPPSEIVSFHSDVMTLEPGDLFSTGTPGAA 249 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRV 43 ++PGD + + +E+IGT E V Sbjct: 250 --------HIEPGDEVRAVVESIGTVEAPV 271 >UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Burkholderia phytofirmans PsJN|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia phytofirmans PsJN Length = 346 Score = 94.7 bits (225), Expect = 2e-18 Identities = 59/181 (32%), Positives = 91/181 (50%), Gaps = 2/181 (1%) Frame = -3 Query: 597 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 418 P+ F + S + P+ I + + + E+EL +VIG++ V A ++V I Sbjct: 151 PYFFQRPNSCIAPPDGEIHAESGTEE-LDWELELGIVIGRRGRHVAREDAPNFVAACLIL 209 Query: 417 QDIG--ATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 244 D+ A + ++ + L GK M P GP++V + IG L ++ S+NG Q Sbjct: 210 NDVTDRALIYRQDFPGADWLRGKGMPASMPAGPYLVPASVIGEIDALRLRLSVNGEVMQD 269 Query: 243 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 64 I +P +I LS+ + L PGD+I TGTP G G R FLQ GDVI +EI+ + Sbjct: 270 ELAGDMILDVPRLIEYLSSRVELRPGDVIATGTPAGTGAERG--RFLQDGDVIRAEIDGL 327 Query: 63 G 61 G Sbjct: 328 G 328 >UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Pedobacter sp. BAL39|Rep: Fumarylacetoacetate hydrolase family protein - Pedobacter sp. BAL39 Length = 332 Score = 94.3 bits (224), Expect = 2e-18 Identities = 63/212 (29%), Positives = 98/212 (46%), Gaps = 23/212 (10%) Frame = -3 Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424 + P + + + GP + I+ D + + E+E+ +VIGKK + ++ A DY+ GY Sbjct: 109 QYPIFYFTNHNAIQGPGE-IECMPDHFQKLDFELEVAIVIGKKGRNITAAEADDYIAGYM 167 Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI------------GNPQNLN 280 I D+ A + + + L K D IGPW+VT DE+ G NL Sbjct: 168 IMNDMSARTLQMEEMLLNLGPAKGKDFSTVIGPWLVTPDELEVYKTAAKSGHTGISYNLE 227 Query: 279 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG--------GVGVY 124 +KC +NG Q N +II R + +LPGD+I +GT G G G+ Sbjct: 228 MKCLVNGQQVSSGNMADMDWTFAEIIERCAYGADILPGDVIGSGTVGTGCFLELNGTGLL 287 Query: 123 RNP---PEFLQPGDVITSEIENIGTFETRVEE 37 P P++LQ GDV+ EI +G + + Sbjct: 288 NEPDFKPQWLQDGDVVEMEITGLGHLSNTIRK 319 >UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep: PlaH - Streptomyces sp. Tu6071 Length = 294 Score = 93.9 bits (223), Expect = 3e-18 Identities = 70/213 (32%), Positives = 100/213 (46%), Gaps = 5/213 (2%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 496 K+ CV LNY P P + K PST+VG + + + + E EL Sbjct: 61 KIACVALNYAPQGSPTGPGRPANPAACSVVLKPPSTLVGHGAVVGHPGEPWE-LRHEAEL 119 Query: 495 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPW 322 VVIG V + A + V GYT A D+ A ++ S + K DTF P+GPW Sbjct: 120 AVVIGTACKGVPAERAAEVVAGYTCADDLTAYVRRAPEEPSGHPPVWAKHFDTFTPLGPW 179 Query: 321 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 + T + P ++ + C +NG +Q T + + +I+A +S M+LLPGD+ILTGTP Sbjct: 180 LTTDLD---PADVPITCRVNGEVRQDGGTRGLLTPVHEIVAVVSRHMSLLPGDVILTGTP 236 Query: 141 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 G G L GD + + IGT V Sbjct: 237 TGSGP-------LSVGDRVEVSLAGIGTLSHTV 262 >UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Moritella sp. PE36|Rep: Fumarylacetoacetate hydrolase family protein - Moritella sp. PE36 Length = 231 Score = 93.5 bits (222), Expect = 4e-18 Identities = 57/182 (31%), Positives = 93/182 (51%), Gaps = 2/182 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+C+G NY DH E PE +F K +++V + + L +D+ + E+E+ ++ Sbjct: 30 KVVCIGRNYLDHIRELGNDVPEQALLFIKPSTSLVALDKPLPLPVDLGECHN-ELEVALL 88 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 313 I +K S + + G + D+ D + + K KA D CP+ P+I Sbjct: 89 IKSPITKGTSIVLSELIWGVGLGLDLTLRDLQSSLKGQGHPWERAKAFDNACPVTPFIPL 148 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 + E G+ NL+ S+N +Q+ T + I ++ ++ TLLPGDI+LTGTP GV Sbjct: 149 A-EFGDVNNLDFTLSVNDQLRQQGCTANMMRSIESLLTEITACFTLLPGDIVLTGTPAGV 207 Query: 132 GV 127 GV Sbjct: 208 GV 209 >UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; Vibrio splendidus 12B01|Rep: Putative uncharacterized protein - Vibrio splendidus 12B01 Length = 274 Score = 93.5 bits (222), Expect = 4e-18 Identities = 66/209 (31%), Positives = 98/209 (46%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +KV VG+N+ H PP + F K PS+++ + I++ ++ V E EL V Sbjct: 80 EKVFAVGMNFASHLASPADAPPPM---FLKLPSSLILTGEVIQVPPK-ARNVHFEGELVV 135 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 VIG++ S+ A + G T+ DI W+ Q L KA D F P+G IV Sbjct: 136 VIGRELSQASEEEAEQAIFGVTVGNDITERSWQGADL--QWLRAKASDGFGPVGNTIVRG 193 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 + N + + +NG Q+ NT+ IHK +++ LS TL PGD+I GTPG Sbjct: 194 IDYNN---IELTTRVNGKVVQQENTSFMIHKPRKVVSYLSYYFTLKPGDLIFMGTPGRTY 250 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 L D ++ IE +GT V Sbjct: 251 A-------LSDKDQVSVTIEGVGTVVNEV 272 >UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Nocardioides sp. JS614|Rep: Fumarylacetoacetate (FAA) hydrolase - Nocardioides sp. (strain BAA-499 / JS614) Length = 280 Score = 93.1 bits (221), Expect = 6e-18 Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 3/189 (1%) Frame = -3 Query: 600 LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTI 421 LP + P TV+GP D I ++ + E+EL VIG+ + +A D+V GYTI Sbjct: 91 LPAYYKGLPDTVIGPEDEIPWPA-YTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTI 149 Query: 420 AQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQ 247 D+ A D + + + GKA D +GP IVT+DE+ +P ++ ++ +NG + Sbjct: 150 WNDLSARDVQAGELPVGMGPGKAKDWDGSNVLGPCIVTADEV-DPHDIELEVRVNGERWG 208 Query: 246 KSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT-PGGVGVYRNPPEFLQPGDVITSEIE 70 +NT H +I S + L PG+++ +GT GG GV +L P D + E Sbjct: 209 GANTRDMHHTFESMIVYASQALMLRPGEVLGSGTATGGSGVELG--RWLAPADTVEMEAS 266 Query: 69 NIGTFETRV 43 IG V Sbjct: 267 GIGVLRNVV 275 >UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7; Saccharomycetales|Rep: Uncharacterized hydrolase YNL168C - Saccharomyces cerevisiae (Baker's yeast) Length = 259 Score = 93.1 bits (221), Expect = 6e-18 Identities = 76/231 (32%), Positives = 113/231 (48%), Gaps = 33/231 (14%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP------------NDTIK-LKMD- 529 K++C+G NY H +E + P+ PF F K S++V P N T L D Sbjct: 11 KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70 Query: 528 -------VSKAVVC--EIELTVVIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDW--E 391 + + V EIEL +++ K S K+ +D + G +A D+ A + E Sbjct: 71 TNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDE 130 Query: 390 KNKKISQLLLGKAMDTFCPIGPWIVTSDEIG----NPQNL-NVKCSINGVQKQKSNTNQF 226 KK + K DTF PI IV+ ++ N Q++ VKCS+NG +Q TN Sbjct: 131 AKKKGLPWTISKGFDTFMPISA-IVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLM 189 Query: 225 IHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 73 +H + I+ +S +++L PGDIILTGTP GVG L+PGD + E+ Sbjct: 190 LHPLHKILQHISTMISLEPGDIILTGTPAGVGE-------LKPGDRVHCEL 233 >UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Marinomonas sp. MWYL1|Rep: Fumarylacetoacetate (FAA) hydrolase - Marinomonas sp. MWYL1 Length = 235 Score = 92.7 bits (220), Expect = 8e-18 Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 7/215 (3%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVV--GPNDTIKLKMDVSKAVV-CEIE 499 +V CVG NY +H +E P + PF F K S VV G +++ + ++ + E+E Sbjct: 26 RVYCVGRNYAEHSKEMGDDPERDPPFFFAKDSSCVVPAGFSESTLITYPMATSQFEYEVE 85 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLGKAMDTFCPIGP 325 L + IGK + + + +LGY + D+ D + KK +GK+ D PI P Sbjct: 86 LVIAIGKGGRNLTLQQSREAILGYAVGLDMTRRDLQSQAKKKGRPWEVGKSFDESAPISP 145 Query: 324 WIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 148 ++ +D + N + +NG KQ S+ I ++I +LS V L PGD+I+TG Sbjct: 146 ILLKTDLLADNVSKAEIGLKVNGDLKQISHVTNLTWSIEEVICKLSEVFELRPGDLIMTG 205 Query: 147 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 TP VG + GD + + +E++G V Sbjct: 206 TPENVGA-------VVVGDEMQAWVEHLGEIRVSV 233 >UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase precursor; n=4; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase precursor - Polaromonas naphthalenivorans (strain CJ2) Length = 245 Score = 92.7 bits (220), Expect = 8e-18 Identities = 63/212 (29%), Positives = 105/212 (49%), Gaps = 4/212 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC-EIELTV 490 +V C+G NY+ + + P E+P F K + VV + L + C EIEL V Sbjct: 30 RVFCIGRNYR--WSQDEAMPQEMPAWFMKPANAVVHAHGV--LPYPPATGDFCHEIELVV 85 Query: 489 VIGKKASKVDSSHAFDY-VLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWI 319 IG+ + + + + GY D+ D ++ K + KA D P P + Sbjct: 86 AIGRGGRDIAPAQVEPHHIWGYAAGLDLTRRDLQQQAKRAGGPWEAAKAFDHSAPCTP-L 144 Query: 318 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 139 V + G+P+ V ++NG+++Q+++ + + + +++A LS +TL+PGD+I TGTP Sbjct: 145 VPAAACGHPRQGAVWLTVNGIERQRADVSGLLWPVAELVAMLSRSVTLMPGDLIYTGTPA 204 Query: 138 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 GVG LQPGDV+ + +G F V Sbjct: 205 GVGP-------LQPGDVVQGGVAGVGQFSMTV 229 >UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|Rep: Bll3146 protein - Bradyrhizobium japonicum Length = 262 Score = 91.9 bits (218), Expect = 1e-17 Identities = 54/166 (32%), Positives = 81/166 (48%), Gaps = 1/166 (0%) Frame = -3 Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430 PPE P K +++ P I+ E EL +VIG+ ++V A ++ G Sbjct: 81 PPE-PLYLLKATTSIAAPGAVIRRPSYYDGKTTYEGELGIVIGRTCARVSPGEADSFIFG 139 Query: 429 YTIAQDIGATD-WEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQ 253 YT DI A D + Q K +D + P GP I T + P L V+ +NG + Sbjct: 140 YTCVNDITANDILTSDPTFPQWARAKGIDDYGPFGPVIATGLD---PAKLVVRTILNGAE 196 Query: 252 KQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 115 +Q + I ++++R+S+ MTLLPGD+I GT GVGV + P Sbjct: 197 RQNYPISDMIFSAQELVSRISHDMTLLPGDLIAVGTSVGVGVMKEP 242 >UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA) hydrolase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 320 Score = 91.5 bits (217), Expect = 2e-17 Identities = 60/201 (29%), Positives = 96/201 (47%), Gaps = 12/201 (5%) Frame = -3 Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424 E+P + P +V+GP D + + +A+ E+E+ +IG+ S + A ++ GYT Sbjct: 98 EIPTFYFGNPYSVIGPQDPVAVPPGC-EALDFELEVAAIIGRAGSNLAPEEARGHIAGYT 156 Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSING 259 I D A D ++++ L K D +GPWIVTSDE+ +L ++ +NG Sbjct: 157 ILNDWSARDLQRHEMQIGLGPAKGKDFANTLGPWIVTSDELEPYRRDGRLHLEMEVFVNG 216 Query: 258 VQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG-------VGVYRNPPEFLQ 100 + +++A S + PGD++ +GT G V R P L+ Sbjct: 217 EKLGDDTLANMAWSFEELVAYASRGTWVRPGDVLGSGTCGSGCLAELWGRVGRQEPPLLE 276 Query: 99 PGDVITSEIENIGTFETRVEE 37 PGDV+ +E IGT E RV E Sbjct: 277 PGDVVRMTVEGIGTIENRVVE 297 >UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Sphingomonas wittichii RW1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Sphingomonas wittichii RW1 Length = 276 Score = 91.5 bits (217), Expect = 2e-17 Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 1/209 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K + +G+NY+ E + PE P ++ + P+ ++G D I L D VVCE EL V Sbjct: 76 KYVGIGINYRATAEALGMAMPEEPVVYVRPPNCIIGDGDRIVLPADGD--VVCEGELAAV 133 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDI-GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 310 IG++ + +V+GYT+ D+ + K+K L K D F P+GP I T Sbjct: 134 IGRRGRDIAEGDVAAHVIGYTLTNDLMDVARFHKDK--GNPSLAKGRDGFAPLGPCIATG 191 Query: 309 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 130 ++ + + +NG + Q + + ++ +S MTL PGD++ G P Sbjct: 192 LDLATAE---LATFVNGARVQAGFARDMLFGVERCVSHISRFMTLEPGDVVALGCP---- 244 Query: 129 VYRNPPEFLQPGDVITSEIENIGTFETRV 43 P + PGD I IGT V Sbjct: 245 ---PTPARIAPGDRIEIGCAPIGTLANEV 270 >UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family protein; n=4; Oligohymenophorea|Rep: Fumarylacetoacetate hydrolase family protein - Tetrahymena thermophila SB210 Length = 233 Score = 91.5 bits (217), Expect = 2e-17 Identities = 69/189 (36%), Positives = 95/189 (50%), Gaps = 9/189 (4%) Frame = -3 Query: 669 DKVLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPN--DTIKLKMDVSKAVVCEIE 499 +K+L +G NY H +E + P+ P IF K P + V PN K++ V EIE Sbjct: 14 NKILAIGKNYVKHVKEMGGSEVPKEPVIFQK-PHSSVLPNIQKGQKVQFFTKNEVHHEIE 72 Query: 498 LTVVIGKKAS----KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFC 337 L ++ K+AS + + DYV GY +A D+ + + K + L K D F Sbjct: 73 LGFMMSKEASHKSFQKSGENWQDYVGGYFLALDLTDRNLQAAAKKAGFPWDLSKGQDKFL 132 Query: 336 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 157 PI +I +++ +P NL + ING QK NT KI D I S MTL PGD+ Sbjct: 133 PISSFI-PKEKVQDPYNLTLHLRINGKTIQKDNTGIMHFKIKDQIEYASKFMTLYPGDLF 191 Query: 156 LTGTPGGVG 130 LTGTP GVG Sbjct: 192 LTGTPDGVG 200 >UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family protein; n=13; Bacillus|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus anthracis Length = 318 Score = 90.2 bits (214), Expect = 4e-17 Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 6/195 (3%) Frame = -3 Query: 603 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 424 ++P + V+GPND + + S+ + E+E+ VIGK+ + A +Y+ GY Sbjct: 107 DIPVFYFTNHRAVIGPNDVV-IGPKKSEKIDYELEIACVIGKEGRNISREQAEEYIFGYC 165 Query: 423 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSING 259 I D A D + + L K D +G +VT +E+ G+ L + +NG Sbjct: 166 IMNDWSARDLQATEMKVGLGPAKGKDFATSLGAHLVTKEELDVYRNGDRYELEMTAHVNG 225 Query: 258 VQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVIT 82 K N + ++I R S +TL PGD+I +GT G G + E+LQ GDV+ Sbjct: 226 KLLSKGNFQDIYYTFAEMIERASEDVTLYPGDVIGSGTVGTGCILELGTEEWLQDGDVVE 285 Query: 81 SEIENIGTFETRVEE 37 I +GT V++ Sbjct: 286 LTITGLGTLRNTVKK 300 >UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Geobacillus|Rep: Hypothetical conserved protein - Geobacillus kaustophilus Length = 260 Score = 89.8 bits (213), Expect = 5e-17 Identities = 55/189 (29%), Positives = 92/189 (48%) Frame = -3 Query: 609 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 430 PPE P ++ K +T+ + L V K + L +VIG+ A++V A D+V G Sbjct: 75 PPEGPVLYMKPANTINAHRRPVLLPRWV-KHLQAAPALGLVIGRTAARVRREQALDFVFG 133 Query: 429 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 YTI D+ ++++ + +A D F P+GPWIV +E +L + +NG Sbjct: 134 YTIVNDLSIPHEQRHRPAVK---EQARDGFAPVGPWIVPKEEASPLSSLTARVYVNGRLV 190 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70 Q+++ ++F + +A ++ MTL PGD++ P + GDV+ EIE Sbjct: 191 QRADPSRFRLPVEQWLAEVTEFMTLYPGDVLFFSWPADA-------PLVTAGDVVRIEIE 243 Query: 69 NIGTFETRV 43 IG E + Sbjct: 244 RIGVLENEI 252 >UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family protein; n=15; Ascomycota|Rep: Fumarylacetoacetate hydrolase family protein - Aspergillus fumigatus (Sartorya fumigata) Length = 235 Score = 89.8 bits (213), Expect = 5e-17 Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 6/210 (2%) Frame = -3 Query: 648 LNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKLKMDVSKAVVCEIELTVVIGKKA 472 LN +E T P+ PF F K PS+++ P + + L VS + E+EL +V+GK Sbjct: 20 LNKSQLQKELNNTKPKQPFFFLKPPSSILLPREGPVLLPKGVS--LHYEVELALVMGKTV 77 Query: 471 SKVDSSH---AFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 +D + A D + Y +A D+ + E KK + K DTF PI I + Sbjct: 78 RDLDPNDEKGALDAIRSYLLAIDMTGRNVQDEAKKKGLPWSIAKGFDTFLPISEEIPKA- 136 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 I +P N ++ S+ +Q +T +++IP +A +S VMTL GD++LTGTP GVG Sbjct: 137 RIPDPHNAFLRLSVGSQLRQADSTGLMLYRIPRQLAEISRVMTLEKGDLVLTGTPKGVGE 196 Query: 126 YRNPPEFLQPGDVITSEIENIGTFETRVEE 37 + +V EIE G E V++ Sbjct: 197 VKAGDVMKASIEVDGKEIEE-GRIEVEVKD 225 >UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Proteobacteria|Rep: Faa-hydrolase family protein - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 265 Score = 89.4 bits (212), Expect = 7e-17 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 6/185 (3%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTV--VGPNDTIKLKMD-VSKAVVCEIE 499 ++ C+G NY H E P E PF F K + V P + ++K EIE Sbjct: 59 RIYCIGRNYAAHAREMGSDPTREPPFFFQKPSDAIQYVAPGKVVDHPYPTLTKNYHYEIE 118 Query: 498 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQLLLGKAMDTFCPIGP 325 L I K + +A +V GY + D+ D + K+ +GK+ D PIGP Sbjct: 119 LVAAINKGGKNISVENALQHVFGYAVGLDMTRRDLQAAMKKEEKPWEIGKSFDMSAPIGP 178 Query: 324 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 145 + IGN + +NG KQ ++ Q I + + I+ LS L+PGDII +GT Sbjct: 179 LHPVAS-IGNFTEGKIWLKVNGQVKQSADLKQMIWSVAEQISNLSKAFELMPGDIIYSGT 237 Query: 144 PGGVG 130 P VG Sbjct: 238 PENVG 242 >UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep: Putative hydrolase - Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 /FAM18) Length = 218 Score = 88.6 bits (210), Expect = 1e-16 Identities = 57/181 (31%), Positives = 89/181 (49%), Gaps = 3/181 (1%) Frame = -3 Query: 663 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 484 + C+G NY H EE K P P +F K +++ TI L + S+ V E EL +++ Sbjct: 16 IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLP-EFSRDVQFECELVLLV 74 Query: 483 GKKASKV-DSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 313 GK + + + V GY + D+ A D + + K L L K + + Sbjct: 75 GKDSDGMGEGEDILGCVAGYGVGLDLTARDIQCHLKAQGLPWLKAKGFRHSACVSDF-AA 133 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 +D IGNP+ + NGV KQ+ +T I+ I +I+ +L+ L GD++ TGTP GV Sbjct: 134 ADRIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTPSGV 193 Query: 132 G 130 G Sbjct: 194 G 194 >UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=8; Actinomycetales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Mycobacterium sp. (strain JLS) Length = 529 Score = 88.2 bits (209), Expect = 2e-16 Identities = 60/201 (29%), Positives = 102/201 (50%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+ V LNY+ ++ P P F K P+++ ++ ++ + E E+ +V Sbjct: 47 KVIAVHLNYRSRAAQRGRFPGH-PSYFLKPPTSLALSGRPVERPAG-TRLLAFEGEIALV 104 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++ +V +++D V A D+G D K S L K D F PIGP ++++ Sbjct: 105 IGRRTRRVSPENSWDCVQFVCAANDLGVYDLRTVDKGSNLR-SKGGDGFTPIGPQLLSAR 163 Query: 306 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 127 I +P L V+ +NG Q +T+ + +IA LS ++TL GD+ILTGTP G V Sbjct: 164 GI-DPARLRVRTWVNGRLAQDGDTSDLLFPFTQLIADLSQLITLEAGDVILTGTPAGSSV 222 Query: 126 YRNPPEFLQPGDVITSEIENI 64 + PGD + +++++ Sbjct: 223 -------VAPGDTVEVQVDSV 236 >UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Alphaproteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 265 Score = 87.8 bits (208), Expect = 2e-16 Identities = 65/211 (30%), Positives = 94/211 (44%), Gaps = 3/211 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 490 +V CVG NY H E P E PF F K +V I + + EIEL V Sbjct: 62 RVFCVGRNYAGHAREMGGDPNREAPFYFTKPADALVPGGGDIPYPPGTAN-LHHEIELVV 120 Query: 489 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIV 316 + + K A + GY + D+ D + K LGKA + PI P +V Sbjct: 121 ALSRSVYKCTPDEASTAIFGYAVGLDMTRRDLQFAARDKGRPWCLGKAFEFSAPISP-LV 179 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 +D ++ ++ +NG +Q + N+ I +P++IA LS L GD+I TGTP G Sbjct: 180 RADAPKLAGSITLE--VNGQIRQSGDLNEMIWSVPEVIAHLSQYYHLGAGDLIFTGTPEG 237 Query: 135 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 VG + GDV+ IE +G E + Sbjct: 238 VGP-------VVAGDVLRGAIEGVGELEVHI 261 >UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate (FAA) hydrolase - Sphingomonas wittichii RW1 Length = 350 Score = 87.8 bits (208), Expect = 2e-16 Identities = 57/189 (30%), Positives = 94/189 (49%), Gaps = 3/189 (1%) Frame = -3 Query: 600 LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGYT 424 +PFI+ ++VG ND + L + E EL +V+ A + +D A +++ GYT Sbjct: 140 MPFIWLATHGSLVGANDDVPLPQ-IGANHDWEAELCLVLAGGAPRYMDPEEAHEHIAGYT 198 Query: 423 IAQDI--GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 250 I D+ G + K + + K+ F P+GP++V + +L +K +NG K Sbjct: 199 IVNDMHTGELFSRDDIKWNADWIAKSPPGFKPVGPYVVPRQFFPDIDDLVIKLWVNGELK 258 Query: 249 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 70 Q N I +A S + +LPGD+++TG+P G G + N +FL PGD + EI Sbjct: 259 QDWPVNDMIFSSEHYVAYASERLKILPGDLLMTGSPPGNGAFHN--QFLVPGDTMDIEIS 316 Query: 69 NIGTFETRV 43 +G R+ Sbjct: 317 YLGRQRNRL 325 >UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isomerase; n=4; Halobacteriaceae|Rep: 2-hydroxyhepta-24-diene-1,7-dioate isomerase - Haloarcula marismortui (Halobacterium marismortui) Length = 238 Score = 87.8 bits (208), Expect = 2e-16 Identities = 59/207 (28%), Positives = 93/207 (44%) Frame = -3 Query: 657 CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGK 478 CVG NY ++ PE P F K P+ ++ I + EL VIG+ Sbjct: 48 CVGRNYAATNDQMDYDRPEEPDFFIKPPTALLAHEQNIPYPPFTDELTYAG-ELAAVIGE 106 Query: 477 KASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIG 298 + +D + D V GYTI D+ A D + KA D P+GPWI T+ + Sbjct: 107 RCHDIDPADVSDAVRGYTILNDVDALDQQGRTA------RKAFDGSGPLGPWIETAVD-- 158 Query: 297 NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRN 118 P ++++ IN ++Q +NT++ + +++A LS T PGD++ G+P G Sbjct: 159 -PTDIDMYTDINDERRQSANTSEMLFGPHEVVAYLSKRFTFRPGDVVAFGSPANPGT--- 214 Query: 117 PPEFLQPGDVITSEIENIGTFETRVEE 37 + P D I + +GT V E Sbjct: 215 ----VAPDDTIEITYDGVGTLRNSVVE 237 >UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Plesiocystis pacifica SIR-1 Length = 287 Score = 87.0 bits (206), Expect = 4e-16 Identities = 62/206 (30%), Positives = 97/206 (47%), Gaps = 2/206 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KVL +G NY H +E P P F K PS ++ + L ++ + E EL +V Sbjct: 82 KVLAIGRNYAAHAKELGNEVPSSPLSFFKPPSCLLASGQPLSLPRGYAR-IDMEAELVLV 140 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 307 IG++A ++ ++ A+ +V Y + DI D +++ K Q K D F P+ + S Sbjct: 141 IGRRARQIAAADAWAHVGAYLMGNDISCRDLQRSDK--QWTRAKGFDGFGPVSAFARLSP 198 Query: 306 --EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 E+ L V+ + Q T+ I +P ++ LS MTL GD+I TGTP GV Sbjct: 199 AAELPPVDALRVRGLLGDELVQDGPTSAMIFDVPTLLEHLSACMTLEVGDLIFTGTPAGV 258 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTF 55 L+PG V E++ +F Sbjct: 259 SA-------LEPGMVTRVELDGPPSF 277 >UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Alcanivorax borkumensis SK2|Rep: Fumarylacetoacetate hydrolase family protein - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 233 Score = 86.6 bits (205), Expect = 5e-16 Identities = 62/204 (30%), Positives = 96/204 (47%), Gaps = 3/204 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 KV+CVG NY DH +E P+ P +F K + + ++ + L + V E+E+ V+ Sbjct: 31 KVVCVGRNYADHAKELGNETPDAPILFMKPATALTSLHEPLVLP-EGQGPVHHEVEMVVL 89 Query: 486 IGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLGKAMDTFCPIGPWIV 316 IGK+ K H V Y I D+ + + +K KA D P+ +I Sbjct: 90 IGKRIRKETRLDHVRFSVAAYGIGLDLTLREVQNQLKEKGHPWERAKAFDGAAPVSGFI- 148 Query: 315 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 + I Q+L V +N KQ +T Q + ++++ +S TL PGD++ TGTP G Sbjct: 149 DARGISVRQDLGVTLELNDAVKQHGHTGQMLFPTFELLSEISQTFTLEPGDVVFTGTPAG 208 Query: 135 VGVYRNPPEFLQPGDVITSEIENI 64 VG L GD T+ + NI Sbjct: 209 VGP-------LNSGDKFTARLGNI 225 >UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia phytofirmans PsJN Length = 257 Score = 86.6 bits (205), Expect = 5e-16 Identities = 48/179 (26%), Positives = 85/179 (47%) Frame = -3 Query: 672 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 493 ND+ L H K PP+ P ++ K +T+ G + + D + V L Sbjct: 49 NDRAALAALGDAVHAAPYK-APPQAPVLYLKPRNTLAGHRARVGVPDD-ALGVEVGASLG 106 Query: 492 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 313 +V+G+ A++V + AFDY+ GYT+ D+ + + +A D FC +GP +V Sbjct: 107 IVVGRTATRVGVAQAFDYIAGYTLVADLSVPHASVYRPSVRF---RARDGFCVVGPVVVA 163 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 S + P NL ++ + ++T + + ++A +++ MTL GD+I G P G Sbjct: 164 SHHVATPDNLAIRVQLGSRDAFTASTASSVRNVAQLVADVTDFMTLSAGDVITLGVPHG 222 >UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xanthomonadaceae|Rep: Fumarylacetoacetate hydrolase - Xanthomonas oryzae pv. oryzae Length = 290 Score = 85.8 bits (203), Expect = 9e-16 Identities = 63/212 (29%), Positives = 98/212 (46%), Gaps = 11/212 (5%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPP-------ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 508 ++ CVG N+ DH E + P + F + VVG D I +K + Sbjct: 79 RIYCVGRNFADHAREMGASAPASKAERGQPTFFMKPADAIVVGHGDQIPYPPG-TKELHH 137 Query: 507 EIELTVVIGKKA--SKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTF 340 E+EL V +G A ++ A + GY + D+ D + K L + K D Sbjct: 138 EVELVVALGSDAPAGELPVEQAERLIYGYGVGLDLTRRDLQAAAKAKGLPWDIAKGFDHS 197 Query: 339 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 160 PI +V + E+G + LN+ +NG +Q+S +Q I +P+I+ LS + L GD+ Sbjct: 198 APISE-LVHAGEVGVLEALNLSLEVNGQVRQQSLLDQMIWNVPEILHALSKLYALRAGDL 256 Query: 159 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 64 I GTP GVG L PGD ++ +EN+ Sbjct: 257 IFMGTPAGVGP-------LLPGDQFSARLENV 281 >UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=16; Bacteroidetes|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Psychroflexus torquis ATCC 700755 Length = 204 Score = 85.8 bits (203), Expect = 9e-16 Identities = 62/211 (29%), Positives = 97/211 (45%), Gaps = 2/211 (0%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K++C+G NY H E K PE P +F K S+V+ N+ + +K V E+E+ V Sbjct: 2 KLICIGRNYAKHISELKNEKPEHPVVFLKPDSSVLLKNNPFIIPA-FTKEVHHEVEILVK 60 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVT 313 I K + + A Y + D A D + K L KA D IG + Sbjct: 61 INKVGKHIQTKFAHKYYDEIGLGIDFTARDIQNQLKEQGLPWEKAKGFDGAAVIGETWLP 120 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 133 D + N++ + N Q +T++ + +I ++IA +S TL GD+I TGTP GV Sbjct: 121 KDRFQDLNNIDFRLEKNKTAVQSGSTSEMLWRIDELIAHVSEYFTLKIGDVIFTGTPAGV 180 Query: 132 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 40 G ++ GD + IE+ F +V+ Sbjct: 181 G-------RVEEGDHLEGFIEDTSCFSIQVK 204 >UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Roseobacter sp. CCS2|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Roseobacter sp. CCS2 Length = 257 Score = 85.4 bits (202), Expect = 1e-15 Identities = 60/171 (35%), Positives = 83/171 (48%), Gaps = 1/171 (0%) Frame = -3 Query: 645 NYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK 466 N+ E KL P+ P F K S++ GPN + L ++ + VV E EL +VIGK Sbjct: 61 NFHAAAERNKLDIPQHPLFFLKPLSSLAGPNAQVALPPNIGR-VVYEGELGIVIGKTCKN 119 Query: 465 VDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQ 289 + A +LGYT DI A D ++ Q K D F IGP I T N + Sbjct: 120 ISVDAAESAILGYTCVNDITALDILFEDPSFPQWTRAKGYDGFGVIGPVIQTDL---NWR 176 Query: 288 NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 136 +L VK +N ++Q + I I+++LS MTL PGD+I GT G Sbjct: 177 DLTVKVMVNDRERQSYPASDMIMNPAQIVSQLSTDMTLEPGDVIACGTSIG 227 >UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Polaribacter dokdonensis MED152|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Polaribacter dokdonensis MED152 Length = 203 Score = 85.4 bits (202), Expect = 1e-15 Identities = 56/177 (31%), Positives = 85/177 (48%), Gaps = 2/177 (1%) Frame = -3 Query: 666 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 487 K+L +G NY ++ FIF+K P + + N + ++ ++ E+EL V Sbjct: 2 KILGIGSNYVTDLKDIPEKKKGKKFIFSK-PESSLAVNCDVPYPSSITNELIYEVELVVK 60 Query: 486 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFCPIGPWIVT 313 IGK+ + A Y+ I D A D N + ++ K D PI + Sbjct: 61 IGKEGKNITKEEANSYISEIAIGIDYTAKDILTNARETKHPWEFAKGFDGAAPISSFKPI 120 Query: 312 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 142 +D + N++ ING +KQKSNT I+ DII+ +S MTL PGD+I TGTP Sbjct: 121 TDY--DLANIDFDLKINGEEKQKSNTAYMINNFADIISFISEYMTLQPGDLIFTGTP 175 >UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate (FAA) hydrolase - Sphingomonas wittichii RW1 Length = 317 Score = 85.0 bits (201), Expect = 2e-15 Identities = 54/157 (34%), Positives = 75/157 (47%), Gaps = 2/157 (1%) Frame = -3 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFCP 334 E+E ++GK + + A ++ GYTI D+ A D + Q+ GK D P Sbjct: 155 ELEWACIVGKGGRNISPAQARAHIFGYTIFNDLSARDVQLAVMAGQIGPGAGKDFDNSNP 214 Query: 333 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 154 IGP IVT+D I +P L + S+NG Q + +T H D + LS L G+II Sbjct: 215 IGPCIVTADAIPDPYALAMTASVNGEQWSRGSTASMHHSFEDAVVMLSRDRQLHAGEIIA 274 Query: 153 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 +GT G L PGDV+ +E IGT T V Sbjct: 275 SGTV-LTGCGFELQRRLSPGDVVELYVEAIGTLTTTV 310 >UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Roseiflexus|Rep: Fumarylacetoacetate (FAA) hydrolase - Roseiflexus sp. RS-1 Length = 333 Score = 85.0 bits (201), Expect = 2e-15 Identities = 47/163 (28%), Positives = 75/163 (46%), Gaps = 8/163 (4%) Frame = -3 Query: 507 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 328 E+E+ VIG+ + A DY+ GY + D A D ++ + I+ K+ D IG Sbjct: 169 ELEVACVIGRSGRDISPEEAGDYIAGYLLLNDWTARDVQREELIAGFAFSKSKDAATSIG 228 Query: 327 PWIVTSDEI------GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 166 PW+ T DE+ NL + +NGV++ + N + +IA S TL PG Sbjct: 229 PWLATPDELQEYALDDGQFNLTLIARVNGVEQSRGNLRDLTYSFAQMIAIASEGCTLFPG 288 Query: 165 DIILTGTPGG--VGVYRNPPEFLQPGDVITSEIENIGTFETRV 43 D+I G GG + +L+P D++ E +G R+ Sbjct: 289 DMIACGAIGGSLLEATNGQGPWLEPDDLVELEAGGLGILRNRI 331 >UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate isomerase; n=2; Sulfolobus|Rep: 2-hydroxyhepta-2 ,4-diene-1,7-dioate isomerase - Sulfolobus solfataricus Length = 288 Score = 85.0 bits (201), Expect = 2e-15 Identities = 68/226 (30%), Positives = 108/226 (47%), Gaps = 21/226 (9%) Frame = -3 Query: 654 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 475 VG+N K+ +E +P F K P+ + I D A+ E+E+ V+ K Sbjct: 66 VGVNDKNEAKEMVKSPK----FFIKLPTVAIAHRQPIISPPD---AIRPEVEIGVITRFK 118 Query: 474 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK------------ISQLLL------GKAM 349 V S Y+LGYT+ DI K + +LL+ K Sbjct: 119 MKDVSRSDVKKYILGYTVFNDITYPPGLKEDSYYAMRRDPTDGNVKKLLMRGTHFRNKVR 178 Query: 348 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 169 DTF PIGP+IVT +EIG+ +L ++ NG Q +++FI I +I++ LS ++T+ P Sbjct: 179 DTFAPIGPYIVTEEEIGDVNSLRMRSYYNGELVQDGYSSEFIFSIEEILSELSKIVTIPP 238 Query: 168 GDIILTGTPGGVGVYRNPPEF-LQP--GDVITSEIENIGTFETRVE 40 +I TG+ G V + EF L+P ++ +E+E IG E ++ Sbjct: 239 FSVISTGSIGYTNV-SDASEFNLKPIESALMVAEVEKIGRLENPIK 283 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 751,574,244 Number of Sequences: 1657284 Number of extensions: 16732770 Number of successful extensions: 45688 Number of sequences better than 10.0: 341 Number of HSP's better than 10.0 without gapping: 43218 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 45079 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 53305790091 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -