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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV11d14f
         (606 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X68836-1|CAA48726.1|  395|Homo sapiens S-adenosylmethionine synt...   292   5e-79
DQ083239-1|AAY85355.1|  395|Homo sapiens methionine adenosyltran...   292   5e-79
BC001854-1|AAH01854.1|  395|Homo sapiens methionine adenosyltran...   292   5e-79
BC001686-1|AAH01686.1|  395|Homo sapiens methionine adenosyltran...   292   5e-79
AC016753-1|AAY24339.1|  395|Homo sapiens unknown protein.             292   5e-79
X69078-1|CAA48822.1|  395|Homo sapiens methionine adenosyltransf...   277   2e-74
D49357-1|BAA08355.1|  395|Homo sapiens S-adenosylmethionine synt...   277   2e-74
BC018359-1|AAH18359.1|  395|Homo sapiens methionine adenosyltran...   277   2e-74
AL359195-2|CAI13695.1|  395|Homo sapiens methionine adenosyltran...   277   2e-74
AL359195-3|CAI13696.1|  145|Homo sapiens methionine adenosyltran...   128   2e-29
BC028352-1|AAH28352.1|  691|Homo sapiens TBC1 domain family, mem...    30   5.5  
AK022147-1|BAB13971.1|  674|Homo sapiens protein ( Homo sapiens ...    30   7.3  

>X68836-1|CAA48726.1|  395|Homo sapiens S-adenosylmethionine
           synthetase protein.
          Length = 395

 Score =  292 bits (717), Expect = 5e-79
 Identities = 137/173 (79%), Positives = 157/173 (90%), Gaps = 1/173 (0%)
 Frame = +2

Query: 89  MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 265
           MNG  + NG H   +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1   MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57

Query: 266 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 445
           T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58  TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117

Query: 446 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT+VLAHKLN K+AELRRN
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRN 170


>DQ083239-1|AAY85355.1|  395|Homo sapiens methionine
           adenosyltransferase II protein.
          Length = 395

 Score =  292 bits (717), Expect = 5e-79
 Identities = 137/173 (79%), Positives = 157/173 (90%), Gaps = 1/173 (0%)
 Frame = +2

Query: 89  MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 265
           MNG  + NG H   +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1   MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57

Query: 266 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 445
           T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58  TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117

Query: 446 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT+VLAHKLN K+AELRRN
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRN 170


>BC001854-1|AAH01854.1|  395|Homo sapiens methionine
           adenosyltransferase II, alpha protein.
          Length = 395

 Score =  292 bits (717), Expect = 5e-79
 Identities = 137/173 (79%), Positives = 157/173 (90%), Gaps = 1/173 (0%)
 Frame = +2

Query: 89  MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 265
           MNG  + NG H   +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1   MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57

Query: 266 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 445
           T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58  TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117

Query: 446 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT+VLAHKLN K+AELRRN
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRN 170


>BC001686-1|AAH01686.1|  395|Homo sapiens methionine
           adenosyltransferase II, alpha protein.
          Length = 395

 Score =  292 bits (717), Expect = 5e-79
 Identities = 137/173 (79%), Positives = 157/173 (90%), Gaps = 1/173 (0%)
 Frame = +2

Query: 89  MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 265
           MNG  + NG H   +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1   MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57

Query: 266 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 445
           T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58  TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117

Query: 446 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT+VLAHKLN K+AELRRN
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRN 170


>AC016753-1|AAY24339.1|  395|Homo sapiens unknown protein.
          Length = 395

 Score =  292 bits (717), Expect = 5e-79
 Identities = 137/173 (79%), Positives = 157/173 (90%), Gaps = 1/173 (0%)
 Frame = +2

Query: 89  MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 265
           MNG  + NG H   +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1   MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57

Query: 266 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 445
           T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58  TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117

Query: 446 AAGVHENRNDEEVGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           A GVH +RN+E++GAGDQGLMFGYATDETEECMPLT+VLAHKLN K+AELRRN
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRN 170


>X69078-1|CAA48822.1|  395|Homo sapiens methionine
           adenosyltransferase protein.
          Length = 395

 Score =  277 bits (679), Expect = 2e-74
 Identities = 123/161 (76%), Positives = 150/161 (93%)
 Frame = +2

Query: 122 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 301
           + + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11  HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69

Query: 302 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 481
           EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+
Sbjct: 70  EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129

Query: 482 VGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           VGAGDQGLMFGYATDETEECMPLT++LAHKLN ++A+LRR+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRS 170


>D49357-1|BAA08355.1|  395|Homo sapiens S-adenosylmethionine
           synthetase protein.
          Length = 395

 Score =  277 bits (679), Expect = 2e-74
 Identities = 123/161 (76%), Positives = 150/161 (93%)
 Frame = +2

Query: 122 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 301
           + + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11  HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69

Query: 302 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 481
           EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+
Sbjct: 70  EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129

Query: 482 VGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           VGAGDQGLMFGYATDETEECMPLT++LAHKLN ++A+LRR+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRS 170


>BC018359-1|AAH18359.1|  395|Homo sapiens methionine
           adenosyltransferase I, alpha protein.
          Length = 395

 Score =  277 bits (679), Expect = 2e-74
 Identities = 123/161 (76%), Positives = 150/161 (93%)
 Frame = +2

Query: 122 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 301
           + + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11  HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69

Query: 302 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 481
           EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+
Sbjct: 70  EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129

Query: 482 VGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           VGAGDQGLMFGYATDETEECMPLT++LAHKLN ++A+LRR+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRS 170


>AL359195-2|CAI13695.1|  395|Homo sapiens methionine
           adenosyltransferase I, alpha protein.
          Length = 395

 Score =  277 bits (679), Expect = 2e-74
 Identities = 123/161 (76%), Positives = 150/161 (93%)
 Frame = +2

Query: 122 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 301
           + + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11  HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69

Query: 302 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEE 481
           EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+
Sbjct: 70  EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129

Query: 482 VGAGDQGLMFGYATDETEECMPLTVVLAHKLNQKIAELRRN 604
           VGAGDQGLMFGYATDETEECMPLT++LAHKLN ++A+LRR+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRS 170


>AL359195-3|CAI13696.1|  145|Homo sapiens methionine
           adenosyltransferase I, alpha protein.
          Length = 145

 Score =  128 bits (308), Expect = 2e-29
 Identities = 57/85 (67%), Positives = 75/85 (88%), Gaps = 3/85 (3%)
 Frame = +2

Query: 359 HIGYDDSSK---GFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQGLMFGYATDE 529
           H+  D ++K   GFD+KTC+V++AL+QQSP+IA  VH +RN+E+VGAGDQGLMFGYATDE
Sbjct: 23  HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDE 82

Query: 530 TEECMPLTVVLAHKLNQKIAELRRN 604
           TEECMPLT++LAHKLN ++A+LRR+
Sbjct: 83  TEECMPLTIILAHKLNARMADLRRS 107



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 42/81 (51%), Positives = 49/81 (60%)
 Frame = +2

Query: 161 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKV 340
           ESVGEGHPDK+CDQISDA+LDAHL QDP+AKVAC    KT  VL+  E  S        +
Sbjct: 1   ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHL 60

Query: 341 VRETVKHIGYDDSSKGFDYKT 403
            R   + +G  D    F Y T
Sbjct: 61  DRNE-EDVGAGDQGLMFGYAT 80


>BC028352-1|AAH28352.1|  691|Homo sapiens TBC1 domain family, member
           15 protein.
          Length = 691

 Score = 30.3 bits (65), Expect = 5.5
 Identities = 20/66 (30%), Positives = 31/66 (46%)
 Frame = +2

Query: 50  WANSKFRMPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAH 229
           W   K + P T+ M G++K   + +D   GS       S  +  P +M D +SDAI    
Sbjct: 235 WKKIK-KDPYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLK 288

Query: 230 LNQDPD 247
           +NQ  +
Sbjct: 289 INQQEE 294


>AK022147-1|BAB13971.1|  674|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12085 fis, clone HEMBB1002510, weakly similar to
           GYP7 PROTEIN. ).
          Length = 674

 Score = 29.9 bits (64), Expect = 7.3
 Identities = 18/58 (31%), Positives = 28/58 (48%)
 Frame = +2

Query: 74  PETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPD 247
           P T+ M G++K   + +D   GS       S  +  P +M D +SDAI    +NQ  +
Sbjct: 225 PYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLKINQQEE 277


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,022,201
Number of Sequences: 237096
Number of extensions: 2220660
Number of successful extensions: 8290
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8159
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8290
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6410414940
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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