BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fmgV11a18r (701 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 264 1e-69 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 263 3e-69 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 259 4e-68 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 254 1e-66 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 242 7e-63 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 239 4e-62 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 230 3e-59 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 214 2e-54 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 212 6e-54 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 209 4e-53 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 204 1e-51 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 198 1e-49 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 198 1e-49 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 194 2e-48 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 193 3e-48 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 192 5e-48 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 187 3e-46 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 186 4e-46 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 185 1e-45 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 184 1e-45 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 181 1e-44 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 181 2e-44 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 178 1e-43 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 178 1e-43 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 176 5e-43 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 174 2e-42 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 174 2e-42 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 174 2e-42 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 170 3e-41 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 167 2e-40 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 167 2e-40 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 167 3e-40 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 166 5e-40 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 164 2e-39 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 162 9e-39 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 162 9e-39 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 161 1e-38 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 160 3e-38 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 157 2e-37 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 157 3e-37 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 157 3e-37 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 156 6e-37 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 154 2e-36 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 153 3e-36 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 153 5e-36 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 151 1e-35 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 151 1e-35 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 151 2e-35 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 151 2e-35 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 150 4e-35 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 149 5e-35 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 149 9e-35 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 148 2e-34 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 147 2e-34 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 146 3e-34 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 146 3e-34 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 146 5e-34 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 146 6e-34 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 145 8e-34 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 145 8e-34 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 144 2e-33 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 143 3e-33 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 143 3e-33 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 143 3e-33 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 142 6e-33 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 142 7e-33 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 142 7e-33 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 142 1e-32 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 142 1e-32 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 141 2e-32 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 141 2e-32 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 140 3e-32 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 140 3e-32 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 140 4e-32 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 139 5e-32 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 139 7e-32 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 139 7e-32 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 138 9e-32 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 138 2e-31 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 137 3e-31 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 136 6e-31 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 135 9e-31 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 135 1e-30 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 135 1e-30 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 134 1e-30 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 134 1e-30 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 134 3e-30 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 133 3e-30 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 133 3e-30 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 132 6e-30 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 132 8e-30 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 131 1e-29 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 131 2e-29 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 131 2e-29 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 130 2e-29 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 130 2e-29 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 128 1e-28 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 128 1e-28 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 128 1e-28 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 128 1e-28 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 128 2e-28 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 128 2e-28 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 127 2e-28 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 127 3e-28 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 126 4e-28 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 126 5e-28 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 126 5e-28 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 126 7e-28 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 126 7e-28 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 125 9e-28 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 125 1e-27 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 124 2e-27 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 124 2e-27 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 124 2e-27 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 124 2e-27 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 124 3e-27 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 123 4e-27 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 123 4e-27 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 123 5e-27 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 123 5e-27 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 122 9e-27 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 121 1e-26 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 121 1e-26 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 121 1e-26 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 121 1e-26 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 121 2e-26 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 120 3e-26 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 120 3e-26 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 120 3e-26 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 120 5e-26 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 119 6e-26 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 119 8e-26 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 119 8e-26 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 119 8e-26 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 118 2e-25 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 118 2e-25 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 117 2e-25 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 117 2e-25 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 117 3e-25 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 116 4e-25 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 116 6e-25 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 116 7e-25 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 115 1e-24 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 115 1e-24 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 114 2e-24 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 113 3e-24 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 113 3e-24 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 113 3e-24 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 113 3e-24 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 113 4e-24 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 113 4e-24 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 113 4e-24 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 113 5e-24 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 112 7e-24 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 112 7e-24 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 112 9e-24 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 111 1e-23 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 111 2e-23 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 111 2e-23 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 111 2e-23 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 110 4e-23 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 110 4e-23 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 110 4e-23 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 110 4e-23 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 110 4e-23 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 110 4e-23 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 109 5e-23 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 109 5e-23 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 109 5e-23 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 109 6e-23 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 109 6e-23 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 109 6e-23 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 109 9e-23 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 109 9e-23 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 108 1e-22 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 108 1e-22 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 108 1e-22 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 108 1e-22 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 107 3e-22 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 107 3e-22 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 107 3e-22 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 107 3e-22 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 106 6e-22 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 105 8e-22 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 105 8e-22 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 105 8e-22 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 105 8e-22 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 105 8e-22 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 105 1e-21 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-21 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 105 1e-21 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 104 2e-21 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 103 3e-21 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 103 4e-21 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 103 4e-21 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 103 4e-21 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 102 7e-21 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 102 1e-20 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 102 1e-20 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 101 1e-20 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 101 2e-20 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 100 3e-20 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 99 5e-20 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 99 5e-20 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 99 5e-20 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 100 7e-20 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 99 9e-20 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-19 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 99 1e-19 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 99 1e-19 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 98 2e-19 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 98 2e-19 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 97 3e-19 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 97 4e-19 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 97 4e-19 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 97 4e-19 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 96 8e-19 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 95 1e-18 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 95 1e-18 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 95 2e-18 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 95 2e-18 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 94 3e-18 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 93 6e-18 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 93 6e-18 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 90 4e-17 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 90 4e-17 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 90 4e-17 UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 89 7e-17 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 89 1e-16 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 89 1e-16 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 88 2e-16 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 87 3e-16 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 87 3e-16 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 87 4e-16 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 86 7e-16 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 86 9e-16 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 86 9e-16 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 85 1e-15 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 85 1e-15 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 85 2e-15 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 85 2e-15 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 85 2e-15 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 83 5e-15 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 83 5e-15 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 83 6e-15 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 83 8e-15 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 83 8e-15 UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 83 8e-15 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 82 1e-14 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 82 1e-14 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 82 1e-14 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 81 2e-14 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 81 2e-14 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 81 3e-14 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 81 3e-14 UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 81 3e-14 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 80 5e-14 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 79 8e-14 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 79 8e-14 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 79 8e-14 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 78 2e-13 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 78 2e-13 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 77 6e-13 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 76 7e-13 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 76 7e-13 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 76 7e-13 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 48 8e-13 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 76 1e-12 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 75 1e-12 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 75 2e-12 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 75 2e-12 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 74 4e-12 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 74 4e-12 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 74 4e-12 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 73 5e-12 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 73 5e-12 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 73 9e-12 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 72 1e-11 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 72 2e-11 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 71 3e-11 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 70 5e-11 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 70 6e-11 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 69 1e-10 UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 68 2e-10 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 67 5e-10 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 66 1e-09 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 66 1e-09 UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 64 2e-09 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 64 3e-09 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 64 3e-09 UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 63 6e-09 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 63 6e-09 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 63 6e-09 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 63 7e-09 UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 62 1e-08 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 62 2e-08 UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 62 2e-08 UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 61 2e-08 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 61 3e-08 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 61 3e-08 UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 60 4e-08 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 60 4e-08 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 60 4e-08 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 60 7e-08 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 60 7e-08 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 59 9e-08 UniRef50_A6BFM9 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 58 3e-07 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 57 5e-07 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 56 6e-07 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 56 8e-07 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 56 8e-07 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 56 1e-06 UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 56 1e-06 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 55 2e-06 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 54 3e-06 UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 54 3e-06 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 54 3e-06 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 54 4e-06 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 54 4e-06 UniRef50_Q14LU7 Cluster: Putative aldo/keto reductase n-terminal... 53 6e-06 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 53 8e-06 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 53 8e-06 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 52 1e-05 UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc... 52 1e-05 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 52 1e-05 UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 52 1e-05 UniRef50_Q9RL57 Cluster: Putative oxidoreductase; n=4; Actinomyc... 52 2e-05 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 51 2e-05 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 51 2e-05 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 51 3e-05 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 50 4e-05 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 50 4e-05 UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 50 4e-05 UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 50 6e-05 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 50 7e-05 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 50 7e-05 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 49 1e-04 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 49 1e-04 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 49 1e-04 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 49 1e-04 UniRef50_A1KMW5 Cluster: Putative uncharacterized protein BCG_29... 49 1e-04 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 49 1e-04 UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 49 1e-04 UniRef50_Q5KQ01 Cluster: Pyridoxal reductase, putative; n=2; Fil... 49 1e-04 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 48 3e-04 UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 48 3e-04 UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 47 4e-04 UniRef50_P82810 Cluster: Morphine 6-dehydrogenase; n=1; Oryctola... 47 4e-04 UniRef50_Q8G5I8 Cluster: Possible oxidoreductase in aldo-keto re... 46 7e-04 UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 46 9e-04 UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 46 0.001 UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 45 0.002 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 45 0.002 UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.003 UniRef50_A3I2P1 Cluster: Putative oxidoreductase-possibly Aldo/k... 44 0.003 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003 UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 44 0.003 UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 44 0.004 UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 44 0.005 UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.005 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 44 0.005 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 44 0.005 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 43 0.008 UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla... 43 0.008 UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;... 43 0.008 UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 42 0.011 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 42 0.011 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 42 0.011 UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires... 42 0.015 UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 42 0.015 UniRef50_A4A767 Cluster: Aldo/keto reductase/Endoribonuclease L-... 42 0.015 UniRef50_Q966L2 Cluster: Putative uncharacterized protein; n=2; ... 42 0.015 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 42 0.015 UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 42 0.019 UniRef50_A0QJ98 Cluster: Morphine 6-dehydrogenase; n=1; Mycobact... 42 0.019 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 41 0.026 UniRef50_A0ZZI9 Cluster: Possible oxidoreductase in aldo-keto re... 41 0.034 UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 41 0.034 UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 41 0.034 UniRef50_Q8YUM4 Cluster: Aldo/keto reductase; n=4; Nostocaceae|R... 40 0.045 UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 40 0.045 UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.045 UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 40 0.059 UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 40 0.059 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 40 0.059 UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 40 0.059 UniRef50_A2TIR8 Cluster: Receptor for egg jelly protein 9; n=9; ... 40 0.059 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 40 0.059 UniRef50_UPI00005A55ED Cluster: PREDICTED: hypothetical protein ... 40 0.078 UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 40 0.078 UniRef50_A1WAL7 Cluster: Aldo/keto reductase; n=35; cellular org... 40 0.078 UniRef50_A0VU33 Cluster: Aldo/keto reductase; n=1; Dinoroseobact... 40 0.078 UniRef50_P48507 Cluster: Glutamate--cysteine ligase regulatory s... 40 0.078 UniRef50_Q5FJ72 Cluster: Predicted oxidoreductase; n=1; Lactobac... 39 0.10 UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 39 0.10 UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 39 0.10 UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 39 0.10 UniRef50_UPI0000605361 Cluster: PREDICTED: hypothetical protein;... 39 0.14 UniRef50_Q3DEH0 Cluster: Putative uncharacterized protein; n=2; ... 39 0.14 UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 39 0.14 UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14 UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 39 0.14 UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 39 0.14 UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 38 0.18 UniRef50_A7RWF3 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.18 UniRef50_Q0D184 Cluster: Predicted protein; n=2; Trichocomaceae|... 38 0.18 UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 38 0.18 UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 38 0.24 UniRef50_Q1GLY3 Cluster: Aldo/keto reductase; n=9; Proteobacteri... 38 0.24 UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St... 38 0.24 UniRef50_A5C803 Cluster: Putative uncharacterized protein; n=1; ... 38 0.24 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 38 0.24 UniRef50_UPI000023E73A Cluster: hypothetical protein FG04811.1; ... 38 0.32 UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 38 0.32 UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 38 0.32 UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 38 0.32 UniRef50_Q0IN30 Cluster: Os12g0511100 protein; n=1; Oryza sativa... 38 0.32 UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2; Des... 38 0.32 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 37 0.42 UniRef50_Q3WFS8 Cluster: Aldo/keto reductase; n=1; Frankia sp. E... 37 0.42 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 37 0.42 UniRef50_A0VRG6 Cluster: Putative uncharacterized protein; n=1; ... 37 0.42 UniRef50_Q7S500 Cluster: Predicted protein; n=1; Neurospora cras... 37 0.42 UniRef50_Q4WE64 Cluster: Aldo-keto reductase (AKR), putative; n=... 37 0.42 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 37 0.55 UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 37 0.55 UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55 UniRef50_Q0CQW8 Cluster: Predicted protein; n=3; Eurotiomycetida... 37 0.55 UniRef50_Q0CGX7 Cluster: Predicted protein; n=1; Aspergillus ter... 37 0.55 UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 36 0.73 UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 36 0.73 UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 36 0.73 UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 36 0.73 UniRef50_O13524 Cluster: B2-aldehyde-forming enzyme; n=1; Schizo... 36 0.73 UniRef50_UPI0000D56933 Cluster: PREDICTED: similar to CG4919-PA;... 36 0.96 UniRef50_UPI000018356B Cluster: UPI000018356B related cluster; n... 36 0.96 UniRef50_Q4S2M1 Cluster: Chromosome 17 SCAF14760, whole genome s... 36 0.96 UniRef50_A4T4H4 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 36 0.96 UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 36 1.3 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 36 1.3 UniRef50_Q1J2F9 Cluster: HRDC; n=1; Deinococcus geothermalis DSM... 36 1.3 UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 36 1.3 UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.3 UniRef50_Q9NKP7 Cluster: Putative uncharacterized protein; n=3; ... 36 1.3 UniRef50_Q4P0M3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3 UniRef50_Q2USD3 Cluster: Voltage-gated shaker-like K+ channel; n... 36 1.3 UniRef50_Q0URT8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3 UniRef50_Q0SFJ5 Cluster: Aryl-alcohol dehydrogenase; n=4; Actino... 35 1.7 UniRef50_A3US12 Cluster: Oxidoreductase, aldo/keto reductase fam... 35 1.7 UniRef50_A2TW02 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7 UniRef50_A1SNS8 Cluster: Major facilitator superfamily MFS_1 pre... 35 1.7 UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 35 1.7 UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7 UniRef50_UPI0001552E13 Cluster: PREDICTED: hypothetical protein;... 35 2.2 UniRef50_UPI0000DD8688 Cluster: PREDICTED: hypothetical protein;... 35 2.2 UniRef50_Q7WFM3 Cluster: Conserved hypothetical secreted protein... 35 2.2 UniRef50_Q3JU16 Cluster: Putative uncharacterized protein; n=2; ... 35 2.2 UniRef50_Q3WAH4 Cluster: ABC transporter; n=2; Frankia|Rep: ABC ... 35 2.2 UniRef50_Q12D62 Cluster: Aldo/keto reductase; n=12; Proteobacter... 35 2.2 UniRef50_Q6WN58 Cluster: Glutamate-cysteine ligase modifier subu... 35 2.2 UniRef50_Q54UR7 Cluster: Putative uncharacterized protein; n=2; ... 35 2.2 UniRef50_Q2UT23 Cluster: Voltage-gated shaker-like K+ channel; n... 35 2.2 UniRef50_UPI00015559B0 Cluster: PREDICTED: similar to dopamine r... 34 2.9 UniRef50_O39307 Cluster: 71; n=7; Equid herpesvirus 4|Rep: 71 - ... 34 2.9 UniRef50_Q747Y9 Cluster: Oxidoreductase, aldo/keto reductase fam... 34 2.9 UniRef50_Q6FW57 Cluster: Candida glabrata strain CBS138 chromoso... 34 2.9 UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 34 2.9 UniRef50_P10383 Cluster: Protein ovarian tumor locus; n=6; melan... 34 2.9 UniRef50_UPI00015B8A62 Cluster: UPI00015B8A62 related cluster; n... 34 3.9 UniRef50_UPI00015B487E Cluster: PREDICTED: similar to protease, ... 34 3.9 UniRef50_UPI0000F2E860 Cluster: PREDICTED: hypothetical protein;... 34 3.9 UniRef50_UPI0000EBDB83 Cluster: PREDICTED: hypothetical protein ... 34 3.9 UniRef50_UPI0000DA3A40 Cluster: PREDICTED: hypothetical protein;... 34 3.9 UniRef50_UPI0000D9E78C Cluster: PREDICTED: hypothetical protein,... 34 3.9 UniRef50_UPI00005A28C2 Cluster: PREDICTED: similar to Collagen a... 34 3.9 UniRef50_Q4RAW1 Cluster: Chromosome undetermined SCAF22779, whol... 34 3.9 UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 34 3.9 UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 34 3.9 UniRef50_Q3JKD7 Cluster: Putative uncharacterized protein; n=1; ... 34 3.9 UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 34 3.9 UniRef50_A5ZEM6 Cluster: Putative uncharacterized protein; n=1; ... 34 3.9 UniRef50_Q6C376 Cluster: Similar to sp|O14295 Schizosaccharomyce... 34 3.9 UniRef50_A6R162 Cluster: Predicted protein; n=1; Ajellomyces cap... 34 3.9 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 34 3.9 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 34 3.9 UniRef50_Q90508 Cluster: Vitellogenin-1 precursor (Vitellogenin ... 34 3.9 UniRef50_P40691 Cluster: Auxin-induced protein PCNT115; n=65; ce... 34 3.9 UniRef50_UPI0000E468EB Cluster: PREDICTED: similar to KIAA0732 p... 33 5.1 UniRef50_UPI0000D55EBD Cluster: PREDICTED: similar to CG16857-PA... 33 5.1 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 264 bits (648), Expect = 1e-69 Identities = 117/211 (55%), Positives = 151/211 (71%), Gaps = 1/211 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + YLDLYLIHWP Y+E LFP GK FSD DYVDTW ME LV GLV++IGVS Sbjct: 106 LDYLDLYLIHWPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVS 165 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NFN+KQ++R+L A + P NQ+ECHPYL+Q ++ FC +G+ +TAYSPLGSP RPW K Sbjct: 166 NFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPLGSPARPWVK 225 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 DDP LM+D + +A + GK+ AQ+LIRYQI G++VIPKSVT+ RIASNFDV F+L Sbjct: 226 ADDPVLMDDATVGQLAKKHGKSAAQILIRYQIQLGHVVIPKSVTKERIASNFDVFSFQLD 285 Query: 159 REDVALIDSFDCGGRLVPMTASLGHKHHPFE 67 +D+ + + GR+ P +++ GH HHPFE Sbjct: 286 EDDMKQLAGLERNGRICPESSAFGHPHHPFE 316 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 263 bits (645), Expect = 3e-69 Identities = 112/211 (53%), Positives = 154/211 (72%), Gaps = 1/211 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + YLD+YL+HWP A KE SL P D ++G SDVD+VDTWKAME + ++ L KSIG+S Sbjct: 278 LDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDLTKSIGIS 337 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NFNS Q++RLL+ A + PV+NQ+ECHPYLNQ +L++FC RG+ +T+YSPLGSP RPW K Sbjct: 338 NFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGSPARPWQK 397 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 P DP ++ DPK+K I ++ GK+ AQ+L+RY + GN+VIPKS R+R+ N + DF LS Sbjct: 398 PGDPYVINDPKIKEIGNKYGKSPAQILLRYNVQLGNVVIPKSSNRNRLVENMSIFDFTLS 457 Query: 159 REDVALIDSFDCGGRLVPMTASLGHKHHPFE 67 +D+ I +FDC GR+ P + H +PF+ Sbjct: 458 EDDMKYIGTFDCNGRICPQAEAREHPFYPFK 488 Score = 145 bits (351), Expect = 1e-33 Identities = 77/189 (40%), Positives = 118/189 (62%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V YLDLYLI P A K D + ++TW+AME L E L ++IG+SN Sbjct: 104 VAYLDLYLIERPPACK-----------------DHNLIETWEAMEGLYSEKLTRAIGLSN 146 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FNSKQ+ER+L++ T++P VNQ++CHPYLNQ +L+++C G+ + +YSPLG+ R +P Sbjct: 147 FNSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLGA--RNNIQP 204 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + ++ D ++K IA R KT +++++Y + GNIVI + S +NF DF L+ Sbjct: 205 ESLDVLSDCRIKEIARRYNKTPTEIVLKYNVQLGNIVISDMLIES---ANF--FDFYLAP 259 Query: 156 EDVALIDSF 130 ED++ I +F Sbjct: 260 EDMSYISTF 268 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 259 bits (635), Expect = 4e-68 Identities = 120/214 (56%), Positives = 153/214 (71%), Gaps = 2/214 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP +K FP D SG + SD D+VDTW AME LV EGLVK+IGVSN Sbjct: 102 LDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSN 161 Query: 516 FNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 FN Q+ER+L +K P VNQ+ECHPYL Q++L E+C ++G+ +TAYSPLGSPDRPWA Sbjct: 162 FNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWA 221 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 KP+DP L+EDP++KAIA + KT AQVLIR+ I +VIPKSVT RIA N V DF++ Sbjct: 222 KPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEV 281 Query: 162 SREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 S ED+A + S++ R+ + + HK +PF E Sbjct: 282 SSEDMATLLSYNRNWRVCALMSCAKHKDYPFHAE 315 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 254 bits (623), Expect = 1e-66 Identities = 116/216 (53%), Positives = 156/216 (72%), Gaps = 2/216 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SN Sbjct: 102 LDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISN 161 Query: 516 FNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 FN Q+E +L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWA Sbjct: 162 FNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA 221 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 KP+DP L+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+L Sbjct: 222 KPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFEL 281 Query: 162 SREDVALIDSFDCGGRLVPMTASLGHKHHPFENEEF 55 S +D+ + S++ R+ + + HK +PF +EEF Sbjct: 282 SSQDMTTLLSYNRNWRVCALLSCTSHKDYPF-HEEF 316 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 242 bits (592), Expect = 7e-63 Identities = 112/212 (52%), Positives = 147/212 (69%), Gaps = 2/212 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + YLDLYL+HWP AYK +L+PT +GK F D+DY+DTWKAME LV GLV +IGVS Sbjct: 103 IDYLDLYLMHWPMAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVS 162 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NFN KQ+ RLL A +KPV+ Q+ECHPYL QK L C + +TAYS LGS P+ K Sbjct: 163 NFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGSGHTPYEK 222 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFD-VLDFKL 163 P L+++P + ++A++ G+T AQVL+RYQ SG IVIP+SV++ + NF + DF+L Sbjct: 223 PGSYPLLQNPIIVSVAEKYGRTPAQVLLRYQTQSGIIVIPRSVSKQHMHDNFKRIWDFQL 282 Query: 162 SREDVALIDSFDCGGRLVPMTASLGHKHHPFE 67 + +DV ID DC GR + M A+ GH HHPFE Sbjct: 283 AIDDVKAIDGLDCNGRFMTMKAAYGHPHHPFE 314 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 239 bits (586), Expect = 4e-62 Identities = 116/214 (54%), Positives = 148/214 (69%), Gaps = 2/214 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWPQ ++ PTD G I S ++D W+AME LV +GLVK++GVSN Sbjct: 102 LDYLDLYLIHWPQGFQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSN 161 Query: 516 FNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 FN Q+ERLL +K PV NQVECHPYL Q++L ++C ++G+ ITAYSPLGSPDRP A Sbjct: 162 FNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDRPSA 221 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 KP+DP L+E PK+K IA + KT AQVLIR+ I+ +VIPKSVT SRI N V DF+L Sbjct: 222 KPEDPLLLEIPKIKEIAAKHKKTAAQVLIRFHIERNVVVIPKSVTPSRIQENIQVFDFQL 281 Query: 162 SREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 S ED+A I SF+ R + A+ ++ PF E Sbjct: 282 SEEDMAAILSFNRNWRACGLFAASHNEDFPFHAE 315 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 230 bits (562), Expect = 3e-59 Identities = 109/213 (51%), Positives = 147/213 (69%), Gaps = 3/213 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDG-SLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 V+YL+LYL+HWP AYK +L+PT + K F D+DYVDTW+AME LV EGL ++IGV Sbjct: 103 VKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGV 162 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SNFN +Q+ RLL A +KPVV Q+ECHPYL+QK L C + +TAYS LGS P+ Sbjct: 163 SNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYE 222 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFD-VLDFK 166 KP L++ P + AIA++ +T AQVL+R+Q SG IVIP+SV++ + NF + DF+ Sbjct: 223 KPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFE 282 Query: 165 LSREDVALIDSFDCGGRLVPMTASLGHKHHPFE 67 L+ +D+ I+ DC GR + M A+ GH HHPFE Sbjct: 283 LAVDDIQAINELDCNGRFMTMKAAYGHPHHPFE 315 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 214 bits (523), Expect = 2e-54 Identities = 103/197 (52%), Positives = 133/197 (67%), Gaps = 2/197 (1%) Frame = -3 Query: 639 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 460 +L P D GK+QFSDVDY+DTWKAME L+K G VKSIGVSNFNS+Q+ RLL +KPV Sbjct: 89 NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148 Query: 459 NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD-PQ-LMEDPKLKAIADR 286 NQVEC+P LNQ++L EFC+ + +TAYSPLG P+ PD+ P+ ++DPK+ I + Sbjct: 149 NQVECNPSLNQRKLTEFCKNLDITLTAYSPLGRPNYYEKDPDNMPKPALDDPKVIEIGKK 208 Query: 285 LGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRLVP 106 KT QV++RY +D G I IPKS RI N D+ DFKL+ E++ ++D F G R VP Sbjct: 209 YNKTSGQVILRYLVDIGTIPIPKSSNSERIRQNIDIFDFKLTEEEIKIMDGFHTGQRTVP 268 Query: 105 MTASLGHKHHPFENEEF 55 HK+ PF N EF Sbjct: 269 FNLCTSHKYFPF-NAEF 284 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 212 bits (518), Expect = 6e-54 Identities = 95/199 (47%), Positives = 141/199 (70%), Gaps = 1/199 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SN Sbjct: 104 LEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSN 163 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W P Sbjct: 164 FNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDP 223 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 D+P L+E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S Sbjct: 224 DEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSP 283 Query: 156 EDVALIDSFDCGGR-LVPM 103 E++ +++ + R +VPM Sbjct: 284 EEMKQLNALNKNWRYIVPM 302 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 209 bits (511), Expect = 4e-53 Identities = 101/199 (50%), Positives = 133/199 (66%), Gaps = 2/199 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 + Y+DLY++HWP ++ G +FP ++G I +SDV Y++TW AME LVK G KS+G+ Sbjct: 102 LDYIDLYIMHWPLGFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGL 161 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SNFNSKQL+ +LQH+TV P V QVE HP+L Q L FC R V ++AYSPLG DR W Sbjct: 162 SNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELLNFCRERSVVVSAYSPLGCGDRAWK 221 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 +P + +DP L IA RL K++AQV IR+Q+ G VIPKS T S I N +V DF+L Sbjct: 222 LSGEPSIFDDPGLLKIAQRLRKSIAQVAIRFQVQRGIPVIPKSATPSHIQENINVFDFEL 281 Query: 162 SREDVALIDSFDCGGRLVP 106 S +D+AL+ S LVP Sbjct: 282 SEDDMALLSSLPRRRILVP 300 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 204 bits (499), Expect = 1e-51 Identities = 96/214 (44%), Positives = 138/214 (64%), Gaps = 2/214 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DL LIHWPQ Y E LFP ++GK+++SDVDY++TWKA E K G +SIG+SN Sbjct: 102 LSYVDLMLIHWPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSN 161 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F Q++R+ A VKP QVE HPY Q +L+EFC+ +G+ + YSPLG+P + + Sbjct: 162 FTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRK 221 Query: 336 D-DPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 D DP ++ + + IA GKT AQ+++R+ +DSG IPKSVT RI+ N V DF+L+ Sbjct: 222 DGDPNVLTNEVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISENLAVFDFQLT 281 Query: 159 REDVALIDSFDCGGRLVPMTASLG-HKHHPFENE 61 E+++ ID + R+V ++ G H H PF E Sbjct: 282 AEEISKIDGINKNWRIVDLSQRDGDHPHCPFLEE 315 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 198 bits (483), Expect = 1e-49 Identities = 101/218 (46%), Positives = 140/218 (64%), Gaps = 5/218 (2%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG-LVK 535 ++ Y+DL+L+H P + G + P D +G + FSDVDYV+TWKAME LV G V+ Sbjct: 104 DIGYIDLFLMHSPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVR 163 Query: 534 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 355 SIG+SNFNS+Q+ER+LQ ATVKPV NQVE +P +Q++L FC+ARG+ +TAY P+G P Sbjct: 164 SIGLSNFNSEQIERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMGRPH 223 Query: 354 RPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVL 175 R + ++DPK+ I + GKT QV++RY ID G I IP S R+ N DV Sbjct: 224 R--TTNGNRNALDDPKVLEIGRKYGKTGGQVILRYLIDIGTIPIPYSTNEERMRQNIDVC 281 Query: 174 DFKLSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 DFKL+ E++ + SF R +P HK++PF+ E Sbjct: 282 DFKLTGEEIEYLASFH-SARTIPFLPLKSHKYYPFDLE 318 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 198 bits (482), Expect = 1e-49 Identities = 96/214 (44%), Positives = 134/214 (62%), Gaps = 2/214 (0%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DLYL+HWP +Y + +VDY++TW+ ME +K GL +SIGVSNFN Sbjct: 109 YIDLYLVHWPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFN 168 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA-KPD 334 S+QL RLL+ A++KPV+NQ+E H LNQK+L+EFC ++ + +T YSP G+P R +P Sbjct: 169 SQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSPFGAPGRNNVFQPA 228 Query: 333 DPQL-MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + ++ P + IA + KT AQ+++RY ID G I IPKS + RI N D+ DFKL+ Sbjct: 229 GADISLQSPVITGIAKKYNKTNAQIVLRYVIDIGAIPIPKSSSEKRIKENIDIFDFKLTP 288 Query: 156 EDVALIDSFDCGGRLVPMTASLGHKHHPFENEEF 55 E++A ID DCG R K +PF N EF Sbjct: 289 EEIAAIDKLDCGFRTCSAIEHKDCKEYPF-NIEF 321 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 194 bits (473), Expect = 2e-48 Identities = 95/215 (44%), Positives = 140/215 (65%), Gaps = 6/215 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 529 + Y+DL+LIH P Y+ +G P D +G + SD DYVDTWKAME L++ G V SI Sbjct: 106 LDYVDLFLIHMPFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSI 165 Query: 528 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 GVSNFNS+QLER+L + VKPV NQVEC +NQK L EFC R + +TA+SP G P Sbjct: 166 GVSNFNSEQLERILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRPHLF 225 Query: 348 WAKP-DDPQ-LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVL 175 P D P+ ++++P++ I + K+ AQV++RY + +G + IPKS + + N ++ Sbjct: 226 EKNPKDKPKPVLDEPEIVEIGKKFDKSSAQVVLRYLLQNGVVPIPKSTSAQHLKQNLEIF 285 Query: 174 DFKLSREDVALIDSFDCGGRLVPMTASLGHKHHPF 70 DF+LS +D+A++D F+ R+V ++ HK++PF Sbjct: 286 DFELSSDDMAILDGFNTNQRMVRLSLLKEHKYYPF 320 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 193 bits (471), Expect = 3e-48 Identities = 95/215 (44%), Positives = 130/215 (60%), Gaps = 3/215 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DL++IH P +K LFP D++GK + + D DTWKA+E GLV+SIGVSN Sbjct: 109 LDYMDLFIIHMPMEFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSN 168 Query: 516 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPW 346 FN KQLE +L + KPV NQVECH YLNQ +L EFC+++ + + YS LGS D W Sbjct: 169 FNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERW 228 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 + P L+EDP L IA + +T AQV +RY + G +V+ KS T +RI NF V DF+ Sbjct: 229 IEASTPVLLEDPALTEIAKKHNRTPAQVAMRYHLQRGVVVLAKSFTPARIQQNFQVFDFQ 288 Query: 165 LSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 L ED+ ID + R + + H +P+ E Sbjct: 289 LDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPYSEE 323 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 192 bits (469), Expect = 5e-48 Identities = 101/213 (47%), Positives = 136/213 (63%), Gaps = 4/213 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNF 514 YLDL+LIH P + FP D +G D +DYVDTW+ ME LV +GLV++IGVSNF Sbjct: 107 YLDLFLIHCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNF 166 Query: 513 NSKQLERLLQHATVKPVVN-QVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK- 340 Q++R+L P+ N QVECHP+L Q L EFC+ +G+ +TAYSPLGSP+R K Sbjct: 167 TVAQIQRVLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSPLGSPERVLQKR 226 Query: 339 -PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 DP LMEDP + AIA + G + AQVLIRYQ+ G V+PKSV SRI NF+ L+F+L Sbjct: 227 ATTDPLLMEDPVVCAIAKKKGVSPAQVLIRYQLQRGVAVLPKSVMPSRIQQNFEALNFEL 286 Query: 162 SREDVALIDSFDCGGRLVPMTASLGHKHHPFEN 64 S+E+ + + + RL+ K++PF + Sbjct: 287 SKEEFQALVNLNKNYRLLNFAPMKNMKYYPFND 319 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 187 bits (455), Expect = 3e-46 Identities = 92/216 (42%), Positives = 136/216 (62%), Gaps = 2/216 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYL+H P K ++ G ++ +DVDY+DTW+ ME LV GL +SIG+SN Sbjct: 105 LEYVDLYLMHMPVGQKFHND---SNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSN 161 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD--RPWA 343 FN+ Q ER+L + ++PVVNQVECHP Q++L+E + G+ I AY PL P R W Sbjct: 162 FNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQPARQW- 220 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 P + D + +A + G+T AQ+ +RY + G + +PKS ++RI NF V DF+L Sbjct: 221 ----PPFLYDEHAQNLAKKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRVFDFEL 276 Query: 162 SREDVALIDSFDCGGRLVPMTASLGHKHHPFENEEF 55 S +DVA ++ + G R VP + GHK++PF N+EF Sbjct: 277 SPDDVAGMEQYHTGQRTVPFSGMSGHKYYPF-NDEF 311 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 186 bits (454), Expect = 4e-46 Identities = 92/215 (42%), Positives = 129/215 (60%), Gaps = 3/215 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIH P ++K LFP ++ G F D + TW+A+E GLVKSIGVSN Sbjct: 130 MDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGVSN 189 Query: 516 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDR-PW 346 FN +QLE +L + KPV NQ+ECHPYLNQK++ EFC+++ + + AY LGSP W Sbjct: 190 FNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLGSPGAGKW 249 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 P L+EDP L +I + K+ AQV +RY I G + I KS R+ N +V DF+ Sbjct: 250 VDQSCPILLEDPVLISIGQKYSKSPAQVSMRYMIQRGCVAIAKSFNPDRMKQNLEVFDFQ 309 Query: 165 LSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 LS+E++A ID + R + H +PF ++ Sbjct: 310 LSQEEMAAIDGLNKNMRYWSFSEWEKHPQYPFHSQ 344 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 185 bits (450), Expect = 1e-45 Identities = 89/215 (41%), Positives = 128/215 (59%), Gaps = 3/215 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLY+I P A+K ++P D++GK + + TW+AME GLVKS+GVSN Sbjct: 111 LDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSN 170 Query: 516 FNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-W 346 FN +QLE +L +K PV NQVECHPY Q +L +FC+ + ITAYSPLG+ P W Sbjct: 171 FNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIW 230 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 P L++D L ++ R KT AQ+++R+ I G +VIPKS RI NF + DF Sbjct: 231 VNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFS 290 Query: 165 LSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 L+ E++ I++ + R V + H +PF +E Sbjct: 291 LTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDE 325 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 184 bits (449), Expect = 1e-45 Identities = 95/210 (45%), Positives = 130/210 (61%), Gaps = 1/210 (0%) Frame = -3 Query: 696 VQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + Y+DLYLIHWP + Y + SGK+ SD DY++TWK ME ++GL +SIGVS Sbjct: 363 LDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQGLARSIGVS 418 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NFNS+Q+ RLL+ A +KPV NQVE LNQK L EFC+ + +T YSPLG RP + Sbjct: 419 NFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLG---RPGNR 475 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 +DP ++ + + GKT AQ+ R+ G I IPKSVT+SRI NF++ DF L+ Sbjct: 476 YGITNAWDDPIIQELVKKYGKTPAQIACRFVSQLGAIPIPKSVTKSRIKENFEIFDFSLT 535 Query: 159 REDVALIDSFDCGGRLVPMTASLGHKHHPF 70 E++ I S G R+ PM + K++PF Sbjct: 536 DEEINSIQSIATGERVAPMEDAKESKYYPF 565 Score = 183 bits (445), Expect = 4e-45 Identities = 87/185 (47%), Positives = 123/185 (66%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL+L+HWP A+K +L P D +GKI+FSD DY++TWK ME ++GL +SIG+SNFN Sbjct: 105 YIDLFLVHWPFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFN 164 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 S+Q+ RLL A +KPV NQVE LNQK L EFC+ + +T +SPLG RP + Sbjct: 165 SEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLG---RPGNRHGI 221 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 L ++P+++ +A + KT A + R+ G IPKSVT+SRI N D+ DF L+ E+ Sbjct: 222 QNLWDEPQIQKLAQKYKKTPANIACRFIHQLGVTPIPKSVTKSRIKENLDIFDFSLTPEE 281 Query: 150 VALID 136 V+ I+ Sbjct: 282 VSTIE 286 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 181 bits (441), Expect = 1e-44 Identities = 96/215 (44%), Positives = 131/215 (60%), Gaps = 5/215 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + YLD YL+H+P K+ G LFP ++ GKI +D+DYVD W+ ME L G VKSIGVS Sbjct: 76 LDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEALKATGKVKSIGVS 134 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP--- 349 NF +Q++RLL A + P VNQVE HPYL Q L ++C+++ + +TA+SP GSP RP Sbjct: 135 NFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPFGSPGRPLEF 194 Query: 348 WAKPDDPQ-LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLD 172 +DP L+EDP + +A + +T AQVL+RY I VIPKSV I N + D Sbjct: 195 QTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVKPHHILENTKIFD 254 Query: 171 FKLSREDVALIDSFDCGGRLVPMTASLGHKHHPFE 67 F L ED+ + S + G R +T H +PF+ Sbjct: 255 FTLDEEDMNALKSLNRGWRACIITELEAHYFYPFK 289 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 181 bits (440), Expect = 2e-44 Identities = 90/216 (41%), Positives = 125/216 (57%), Gaps = 3/216 (1%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 N+ Y+DLYLIH+P + K L P D+ G + F VD DTW+AME GL KSIGVS Sbjct: 107 NLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVS 166 Query: 519 NFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW 346 NFN +QLE +L + KPV NQVECH YLNQ +L +C+ + + AY LG+ + Sbjct: 167 NFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKY 226 Query: 345 A-KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 D P L++DP L A+A + +T A + +RYQ+D G + + KS RI N V DF Sbjct: 227 CINEDTPVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDF 286 Query: 168 KLSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 +L+ +D+ ++D D R P H + PF +E Sbjct: 287 QLASDDMKILDGLDRNLRYFPADMFKAHPNFPFFDE 322 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 178 bits (433), Expect = 1e-43 Identities = 92/172 (53%), Positives = 115/172 (66%), Gaps = 2/172 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLD+YLIHWPQ +K AME LV EGLVK++G+SN Sbjct: 128 LSYLDVYLIHWPQGFK--------------------------AMEELVDEGLVKALGISN 161 Query: 516 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 FN Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ ITAYSPLGSPDRPWA Sbjct: 162 FNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYSPLGSPDRPWA 221 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 187 KP+DP L+E+PK+K IA + KT AQVLIR+ I IVIPKSVT +RI N Sbjct: 222 KPEDPSLLEEPKIKEIAAKHKKTTAQVLIRFHIQRNVIVIPKSVTPARIVEN 273 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 178 bits (433), Expect = 1e-43 Identities = 92/218 (42%), Positives = 135/218 (61%), Gaps = 7/218 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYK-EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 ++Y+DLYLIH P +K ++GS P ++G++ +++ ++DTW+A+E L KEG +K++GVS Sbjct: 104 LEYIDLYLIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVS 163 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NF+ QL+ L A VKP QVECH Y Q+ L+ C+ GV +TAY+PLGSP R A+ Sbjct: 164 NFSCNQLQALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAAR 223 Query: 339 PD------DPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDV 178 PD DP L +P +K +A + KT AQ+LIR+ G IPKSV+ RI N Sbjct: 224 PDGVWPEGDPLL--EPIVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVENIST 281 Query: 177 LDFKLSREDVALIDSFDCGGRLVPMTASLGHKHHPFEN 64 DFKLS ED+ ++S + RL ++ H P ++ Sbjct: 282 FDFKLSDEDMHTLNSIETRTRLFIADFAVKHPFFPHDD 319 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 176 bits (428), Expect = 5e-43 Identities = 101/233 (43%), Positives = 133/233 (57%), Gaps = 21/233 (9%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQFSDVDYVDTW 574 + YLDLYLIHWP +K + P D+S + SD D++DTW Sbjct: 93 LNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTW 152 Query: 573 KAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEA 400 +AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL QK L FC++ Sbjct: 153 EAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQS 212 Query: 399 RGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIP 220 R V +TAY PLG + L+++P +K IA GK+ AQ+LIR+QI IVIP Sbjct: 213 RDVSVTAYRPLGG------SCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266 Query: 219 KSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 S+T S I N V DF+L++ D+ I S + RL + H +PF E Sbjct: 267 GSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHNDYPFHIE 319 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 174 bits (424), Expect = 2e-42 Identities = 85/196 (43%), Positives = 124/196 (63%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHW A++ +L P D G +FS + +TW+AME LV++GLVKS+GV+N Sbjct: 101 LDYLDLYLIHWGVAFEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVAN 160 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + L LL +A +KP V+Q+E HPYL Q L FC ++ + +TAYSP GS + P Sbjct: 161 FTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPFGSTEAP---- 216 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++ DP +K +A LGKT AQVL+R+ + VIP+S +RI NF++ F+LS Sbjct: 217 ----VLTDPTVKEVAKGLGKTPAQVLLRWAVQRNTSVIPRSSNATRIKENFEIATFELSN 272 Query: 156 EDVALIDSFDCGGRLV 109 E +A +++ + R V Sbjct: 273 EHMAALNTLNRNKRFV 288 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 174 bits (423), Expect = 2e-42 Identities = 89/189 (47%), Positives = 126/189 (66%), Gaps = 5/189 (2%) Frame = -3 Query: 609 IQFSDVD-YVDTW----KAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 445 +Q S VD Y+ W +AME LV G K+IG+SNF+ K ++R+++ AT++P QVE Sbjct: 84 LQLSYVDLYLMHWPMAYQAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVEL 143 Query: 444 HPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQ 265 HP L Q++L EFC+ + +TAYSPLG+PDRPW K DDP+LMEDP + IA + GK+ AQ Sbjct: 144 HPLLTQEKLIEFCKEHNMTVTAYSPLGAPDRPWVKDDDPKLMEDPIVTGIATKKGKSPAQ 203 Query: 264 VLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRLVPMTASLGH 85 +LIR+ ++ G I IPKSVT SRI +NF+ L+F+L ED+ + + + G R + + H Sbjct: 204 ILIRFCLERGIICIPKSVTPSRIQANFEALNFELDPEDLKTLLAMNIGYRGC-LLDWVNH 262 Query: 84 KHHPFENEE 58 HPF E Sbjct: 263 PQHPFLGPE 271 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 174 bits (423), Expect = 2e-42 Identities = 86/205 (41%), Positives = 129/205 (62%), Gaps = 1/205 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYL+HWP A+ +FP D G + D+DYVDT+KAME LVK G K+IG+SN Sbjct: 100 IDYLDLYLMHWPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISN 159 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA-K 340 F+ ++ERLL+ ++ P V Q+E HP+L Q E+ +++G+ +T YS LG+ + ++ + Sbjct: 160 FSKGEMERLLESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLGNQNEVYSGR 219 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 +L+EDP L AI + GKT AQV + + I G+ V+ KS T RI NF+ DF+L Sbjct: 220 ERYGRLIEDPALAAIGTKYGKTGAQVALAWGITKGHSVLVKSKTPHRIQQNFE-SDFELK 278 Query: 159 REDVALIDSFDCGGRLVPMTASLGH 85 +ED+ I++ D R +A G+ Sbjct: 279 QEDMKAIENIDKKLRFNDSSADFGY 303 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 170 bits (413), Expect = 3e-41 Identities = 87/191 (45%), Positives = 128/191 (67%), Gaps = 3/191 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIH P A+K+ L + G I ++ +TW+AME LV +GL K+IGVSN Sbjct: 105 LDYLDLYLIHIPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSN 164 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK- 340 F+ K+L +LL+ A++ P NQVE HPYL Q++LKEFC+++G+ +TAYSPLG+P R K Sbjct: 165 FSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLGNPGRLVPKE 224 Query: 339 --PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 +P++ME+P +K IA + +VA+VL+R+ I G V+PKS +R + NF L Sbjct: 225 RLEREPKVMEEPVIKEIAAKHNCSVARVLLRWGIQRGYPVLPKSTSRDHLHDNFSALGLV 284 Query: 165 LSREDVALIDS 133 L+ +++A I S Sbjct: 285 LTDDEMAAIKS 295 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 167 bits (407), Expect = 2e-40 Identities = 91/189 (48%), Positives = 114/189 (60%), Gaps = 2/189 (1%) Frame = -3 Query: 687 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 508 LDLYLIHWP A + + FP + V +TW AME L K+GLV+ IGVSNF+ Sbjct: 104 LDLYLIHWPVALQPEVD-FPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSV 162 Query: 507 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA-KPDD 331 L+ +L V+P +NQVE HPYL Q L F EA + ITAYSPLGS DRP A K DD Sbjct: 163 PNLQMILDAGEVRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGSGDRPDAMKADD 222 Query: 330 -PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRE 154 P LM +P + IADR G + AQVL+++ + G VIPKS T + I N D LS + Sbjct: 223 EPTLMANPTINDIADRHGVSPAQVLLQWGVARGTAVIPKSTTPAHIKDNLAAADLDLSAD 282 Query: 153 DVALIDSFD 127 ++ IDS D Sbjct: 283 ELETIDSLD 291 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 167 bits (406), Expect = 2e-40 Identities = 81/215 (37%), Positives = 125/215 (58%), Gaps = 3/215 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLY++H+P K + FP ++ GK VD+ DTW+ +E GLVKSIGVSN Sbjct: 108 LDYVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSN 167 Query: 516 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD-RPW 346 FN +QLER+L + KPV NQVECH YLNQ++L ++CE++ + + AY LG+ + W Sbjct: 168 FNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEW 227 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 + P L+ DP L +A + ++ A + +RY I G + + +S + + N V F+ Sbjct: 228 VDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQ 287 Query: 165 LSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 LS ED+ +D + R +P + H +PF E Sbjct: 288 LSPEDMKTLDGLNKNFRYLPAEFLVDHPEYPFVEE 322 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 167 bits (405), Expect = 3e-40 Identities = 76/175 (43%), Positives = 113/175 (64%), Gaps = 2/175 (1%) Frame = -3 Query: 633 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVV 460 FP D+ ++ ++DTW+AME LV +GL K+IG+SNFN Q+E +L +K P Sbjct: 147 FPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPAT 206 Query: 459 NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLG 280 NQ+ECHP+LNQ++L FC +RG+ +TA++ LGS DR WA D+P ++DP++ AIA + Sbjct: 207 NQIECHPHLNQEKLIHFCRSRGISVTAFACLGSADRSWASADEPSFLDDPQINAIARKNQ 266 Query: 279 KTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGR 115 T AQVLI++QI + KSV+ RI N D++LS +D+ + SF+ R Sbjct: 267 MTPAQVLIKFQIQRNITAVVKSVSPHRIKENIKAFDYELSDDDMKTLMSFNSNWR 321 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 166 bits (403), Expect = 5e-40 Identities = 82/178 (46%), Positives = 118/178 (66%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYLIHWP K+ GS+ ++ VD TWKAME L G ++IGVSN Sbjct: 105 LEYVDLYLIHWPARIKK-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSN 159 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F++K+L LL+ A V P VNQVECHP Q +L+EFC+++GV ++AYSPLGSP W K Sbjct: 160 FSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKS 219 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 D ++++P L +A++LGK+ AQV +R+ + G+ V+PKS RI NF+V D+ + Sbjct: 220 D---VLKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 164 bits (399), Expect = 2e-39 Identities = 92/217 (42%), Positives = 129/217 (59%), Gaps = 9/217 (4%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYK--EDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIG 526 + Y+DLYL+H P EDGS F D+ G ++ ++ W AME LV++GL KSIG Sbjct: 104 LDYVDLYLVHTPFTININEDGS-FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIG 162 Query: 525 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD--- 355 VSNF+ Q+ RLL++ ++P NQ+E H YL Q+ L +FC++ + +TAYSPLGS Sbjct: 163 VSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAK 222 Query: 354 ---RPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF 184 D P LM+ P++K IA GKT AQVL+R+ ID+G IPKS +R+ N Sbjct: 223 FNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNL 282 Query: 183 DVLDFKLSREDVALIDSFDCGGRLVPMTASLGHKHHP 73 DV DF+L+ E+VA + S D R+ G + HP Sbjct: 283 DVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHP 319 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 162 bits (393), Expect = 9e-39 Identities = 86/198 (43%), Positives = 121/198 (61%), Gaps = 6/198 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + Y+D+YLIH P A KE +L D+ G F DVD+ WKAME VKEG KSIG+S Sbjct: 122 LDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLS 181 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW-- 346 NFN Q+ + +A +KP QVE H YL QK+L++FC+ + +TAY+PLGS + Sbjct: 182 NFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLGSHNARLNL 241 Query: 345 --AKPDD-PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVL 175 P + P L+E P +K++A + K+ Q+L+R+ I G + IPKS R SN D+ Sbjct: 242 HRGTPKELPALVELPLIKSLAAKYNKSPGQILLRHTIQEGLVAIPKSSNAQRQKSNIDIF 301 Query: 174 DFKLSREDVALIDSFDCG 121 DFKL+ E++ ID+ D G Sbjct: 302 DFKLTDEEMKKIDALDKG 319 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 162 bits (393), Expect = 9e-39 Identities = 77/214 (35%), Positives = 134/214 (62%), Gaps = 7/214 (3%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDG-----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 526 Y+DL +IHWP + ED L+P +GK+++SDVDY++TWKA+E + G ++SIG Sbjct: 106 YMDLIVIHWPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIG 165 Query: 525 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP- 349 ++NFN Q+E++ +KP V QVE +P+L+Q+ +++FC +G+ +TA+ G+P Sbjct: 166 LANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSAL 225 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 + K +DP L+ + L++IA GK+V QVL+R+ ID + KS RI N ++ F Sbjct: 226 YRKHEDPNLLYNETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNINIFKF 285 Query: 168 KLSREDVALIDSFDCGGRLV-PMTASLGHKHHPF 70 +L+ +++A I + + R++ P+ + H + P+ Sbjct: 286 RLTSQEIARIKALNIDFRILNPLLGNYDHPYFPW 319 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 161 bits (392), Expect = 1e-38 Identities = 92/215 (42%), Positives = 125/215 (58%), Gaps = 5/215 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPT-----DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 532 + YLDLYLIHWP A++ L T DQ+G + V +TW+ ME LV+ GLVKS Sbjct: 115 IGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKS 174 Query: 531 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDR 352 IGVSNFN + L LL +A +KPVVNQVE HPYL Q +L+E+C+ +K+ AYSPLG Sbjct: 175 IGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQ--- 231 Query: 351 PWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLD 172 K D + LK+IA + K+VA V+ ++ G IPKS SRI NF++ D Sbjct: 232 --GKCD---FFSNKILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNIFD 286 Query: 171 FKLSREDVALIDSFDCGGRLVPMTASLGHKHHPFE 67 F+LS +D+ I+S + R G + F+ Sbjct: 287 FQLSNDDIEKINSLNANIRTCSPITFFGTPFYLFD 321 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 160 bits (388), Expect = 3e-38 Identities = 84/213 (39%), Positives = 129/213 (60%), Gaps = 1/213 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVS 520 + Y+DLYL+H P A ++ G D + + + D V ++TWKA+E ++GLV+SIGVS Sbjct: 100 LDYVDLYLMHTPVAARDSG-----DGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVS 154 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NFN +QL ++ H +++PVVNQVEC +Q +L++FC G+ I AYSPLG P +P K Sbjct: 155 NFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNREGILIMAYSPLGKP-KPGKK 213 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 ++ L +A++ G++ AQ+ +R+ I+ G I IPKS R+ N DVL FKL Sbjct: 214 ---HVFLDSSDLNKMAEKYGRSPAQISLRFLIEIGTIPIPKSSKTDRMKENLDVLSFKLE 270 Query: 159 REDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 DV ++SF R + + KH+PF ++ Sbjct: 271 ETDVQALESFVKQQRSMTLDWLKSSKHYPFNDQ 303 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 157 bits (382), Expect = 2e-37 Identities = 77/195 (39%), Positives = 120/195 (61%) Frame = -3 Query: 693 QYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF 514 +YLDLYLIHWP A K D S P + F D+D + W+ ME LV EGLVKSIG+SNF Sbjct: 101 KYLDLYLIHWPIALKVDASNPPKPED----FLDMDITEIWQEMERLVDEGLVKSIGLSNF 156 Query: 513 NSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPD 334 Q+E++++ +KPV+NQVE + YL Q +L+E C++ + + AY P+G +P A Sbjct: 157 TIPQIEKIMKMCRIKPVINQVELNVYLQQNKLREVCKSYNIVVEAYRPIGG--KP-ANES 213 Query: 333 DPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRE 154 D ++D + ++A + KT AQ+ +R+ + +G I +PKS +R+ N+ V ++ LS E Sbjct: 214 DKNCLDDEVVVSLAKKYNKTTAQICLRWLVQNGIIAVPKSTNPNRLLQNYQVFEWSLSNE 273 Query: 153 DVALIDSFDCGGRLV 109 D+ ++ + R V Sbjct: 274 DMKALEKRNLNKRNV 288 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 157 bits (380), Expect = 3e-37 Identities = 86/190 (45%), Positives = 122/190 (64%), Gaps = 7/190 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDG---SLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSI 529 + YLDLYL+H+P A++ G SL P D+ G F D V +DTWKAME LV++GLVK I Sbjct: 94 LDYLDLYLMHYPFAFQNTGIGGSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRI 153 Query: 528 GVSNFNSKQLERL-LQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDR 352 GVSN+ QLERL A P NQVE + Y+ Q L+E+ G+ +T YS LG+PD Sbjct: 154 GVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQGPLREYMHKEGIIVTGYSTLGTPD- 212 Query: 351 PWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRY--QIDSGNIVIPKSVTRSRIASNFDV 178 WAKPD+P +++D +L IA GK+V +V +++ I+ G ++ KSVT RI N + Sbjct: 213 -WAKPDEPVVLKDEELNKIAAETGKSVGEVELKFLLTIEPGASLLAKSVTPERIYKN-NH 270 Query: 177 LDFKLSREDV 148 LDF+L+++ + Sbjct: 271 LDFELTKDQI 280 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 157 bits (380), Expect = 3e-37 Identities = 74/173 (42%), Positives = 110/173 (63%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V YLDLYL+HWP A+K FP + G +++DY+ T++AME L+ G V++IGVSN Sbjct: 100 VAYLDLYLMHWPCAFKGGDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSN 159 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN ++LE LL +V P VNQ+E HPYL Q L +FC+++G+ I AYSPLG+ + Sbjct: 160 FNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGN-----NQT 214 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDV 178 +P+ ++DP + +A L +L + + G +V+ KSVT +RIA+N V Sbjct: 215 GEPRTVDDPLVHRVAGELSLDPGPLLASWGVQRGTVVLSKSVTPARIAANLRV 267 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 156 bits (378), Expect = 6e-37 Identities = 81/190 (42%), Positives = 116/190 (61%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 +QYLDLYL+HWP A++ + T SG Q V +TW+ ME LV GLVKSIG+SN Sbjct: 103 LQYLDLYLVHWPVAFEYTSNDIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGLSN 159 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN + L +L +A +KP NQVE HP+L+Q LK+FC+ + +TAYSPLG Sbjct: 160 FNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLG--------- 210 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + +++ ++ AIA + KT+ VL ++ I VIPKS T SR+A NFD+ +F++ Sbjct: 211 -NGAFVDNEEVGAIAKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEIEE 269 Query: 156 EDVALIDSFD 127 D+ +D D Sbjct: 270 ADMLFLDKMD 279 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 154 bits (373), Expect = 2e-36 Identities = 82/198 (41%), Positives = 116/198 (58%), Gaps = 2/198 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V YL+LYLIHWP + + + F + + +TW+AME +GL K IGVSN Sbjct: 119 VDYLNLYLIHWPVGIRPEKT-FAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSN 177 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA-- 343 F K+L++L+ H KP VNQVE HP L Q L E+C + + ITAYSPLGS DRP + Sbjct: 178 FTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSPLGSMDRPQSLK 237 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 D P +++ P ++AIA+ G + AQV++ + + G IPKSV SR+ N D +L Sbjct: 238 VKDAPAVLDHPVIRAIAETRGCSPAQVVLAWDVQRGISAIPKSVKPSRLLENLQAADIQL 297 Query: 162 SREDVALIDSFDCGGRLV 109 S ++ I++ D RLV Sbjct: 298 SNTELQKIEALDQNFRLV 315 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 153 bits (372), Expect = 3e-36 Identities = 78/171 (45%), Positives = 109/171 (63%), Gaps = 2/171 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 YLDLYLIHWP A++ + +Q+G I DV DTW AME LV++G V+SIGVSN Sbjct: 102 YLDLYLIHWPVAFRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSN 161 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F +++E LL+ A + P VNQ+E HP+L Q+ L E+ +G+ + YSPLG+ Sbjct: 162 FTREKIEELLKTAKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLGNNIY----- 216 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF 184 + P+ ++DP + A +L KT AQVLI + + G +V+PKSVT RI SNF Sbjct: 217 NIPRAVDDPLVIETAKKLNKTPAQVLISWAVQRGTVVLPKSVTPERIESNF 267 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 153 bits (370), Expect = 5e-36 Identities = 73/182 (40%), Positives = 114/182 (62%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYL+HWP + K + P + + F D+ W+AME + GL K+IGVSN Sbjct: 110 MEYVDLYLVHWPISVKPGPPMLPVKREDAVPF---DFEGVWRAMEECHRLGLAKAIGVSN 166 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F +K L++LL AT+ P VNQVE +P Q+ ++E+C A+G+++ AYSPLG + W Sbjct: 167 FTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLGGQN--WI-G 223 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + +ME P L IA GK++AQV +R+ + G IPKS + R+ N ++ D++L++ Sbjct: 224 EGNDVMESPVLADIARARGKSIAQVSLRWIHEQGVTPIPKSYNKERLKQNLEIFDWELTK 283 Query: 156 ED 151 ED Sbjct: 284 ED 285 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 151 bits (367), Expect = 1e-35 Identities = 85/207 (41%), Positives = 118/207 (57%), Gaps = 12/207 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKED--GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 V YLDL+L+HWP A+ + G LFP D G+ V DTW+AME LV+EGLVK IGV Sbjct: 95 VDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRAMEQLVEEGLVKHIGV 154 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SN+ L LL +A +KP+VNQ+E HP+ +FC G+ +TAYSP+G +A Sbjct: 155 SNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIGVTAYSPMGG---SYA 211 Query: 342 KPDDPQ------LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI----VIPKSVTRSRIA 193 P DP ++E LKAIAD G + V + + + N VIPKS T +RI Sbjct: 212 DPRDPSGTQKNVILECKTLKAIADAKGTSPHCVALAWHVKKWNTSMYSVIPKSQTPARIE 271 Query: 192 SNFDVLDFKLSREDVALIDSFDCGGRL 112 +NF + +LS +D+ I++ R+ Sbjct: 272 ANFKCTEVQLSDDDMDAINNIHLNKRI 298 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 151 bits (367), Expect = 1e-35 Identities = 76/209 (36%), Positives = 120/209 (57%), Gaps = 1/209 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLY +H P E F + + + D+V WKAME + + GL ++IG+SN Sbjct: 104 LEYVDLYHVHVPFTVPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSN 163 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD-RPWAK 340 FN +Q++R+L + +KP Q+E H YL Q L +FC+A G+ +TAYSPLGS Sbjct: 164 FNQRQIQRILDNCQIKPANLQIENHIYLQQPELVKFCKANGITVTAYSPLGSKGIEKLLG 223 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 + P L+++P +K IA++LGK+ AQVL+R+ + G IPKS +R+ N D+ F++ Sbjct: 224 REVPDLLDNPVVKDIAEKLGKSPAQVLLRHLLQRGISTIPKSTNPTRLRDNIDLFGFEID 283 Query: 159 REDVALIDSFDCGGRLVPMTASLGHKHHP 73 D+ ++ D R+ G HP Sbjct: 284 DSDMVRLNQLDQNIRICDFGFFPGITKHP 312 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 151 bits (366), Expect = 2e-35 Identities = 87/197 (44%), Positives = 120/197 (60%), Gaps = 5/197 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKS 532 ++YLDLYLIHWP A+ +G +LFP +++ +V VDTWKAM L+ G VK+ Sbjct: 98 LEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKA 157 Query: 531 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDR 352 IGVSNF++K ++ +++ V P VNQ+E HP L Q L +A+ + ITAYSPLG+ Sbjct: 158 IGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGN--- 214 Query: 351 PWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLD 172 P L++ P++K IA++ G T AQVLI + I G+ VIPKSVT SRI NF Sbjct: 215 --NTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSVIPKSVTPSRIGENFK--Q 270 Query: 171 FKLSREDVALIDSFDCG 121 LS+EDV + G Sbjct: 271 VSLSQEDVDAVSKLGEG 287 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 151 bits (365), Expect = 2e-35 Identities = 87/197 (44%), Positives = 116/197 (58%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V Y+DLYLIHWP+ K+ S + GK Y+D+W+A E L KE V++IGVSN Sbjct: 103 VDYIDLYLIHWPRG-KDILS-----KEGK------KYLDSWRAFEQLYKEKKVRAIGVSN 150 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ LE +L TV P+VNQVE HP NQ L+ FC+A+ +K+ A+SPLG Sbjct: 151 FHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLG--------- 201 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +L+ +P L AI + KT AQV++R+ I I IPKSV R RI N D+ DF+L Sbjct: 202 -QGKLLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGA 260 Query: 156 EDVALIDSFDCGGRLVP 106 EDV ID+ + R P Sbjct: 261 EDVMSIDALNTNSRYGP 277 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 150 bits (363), Expect = 4e-35 Identities = 79/190 (41%), Positives = 117/190 (61%), Gaps = 2/190 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDG-SLFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 YLDLYLIHWP A++ +L P D K + ++V DTW A+E LV+ ++SIG+SN Sbjct: 102 YLDLYLIHWPVAFEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISN 161 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F +++ LL+ A + P VNQ+E HPYL Q L ++ + + + AYSPLG+ Sbjct: 162 FTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGNNIY----- 216 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + P++++DP +KAIAD+LGK A +LI + + G V+PKSVT SRI SNF DF + Sbjct: 217 NAPRVVDDPDVKAIADKLGKDPAALLISWAVQRGTAVLPKSVTPSRIESNFQ--DFIIPD 274 Query: 156 EDVALIDSFD 127 + ++ D Sbjct: 275 AEFEALNKLD 284 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 149 bits (362), Expect = 5e-35 Identities = 76/210 (36%), Positives = 120/210 (57%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DL+L+HWP A ED S S+ DY++TW+A E +VK G KSIG+SN Sbjct: 131 LDYVDLFLMHWPIALNEDYS-----------HSNTDYLETWRATEEMVKLGYTKSIGLSN 179 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN Q+ +LQ T+KPV Q+E HP + Q+ L + + G+ + YSP GS + + Sbjct: 180 FNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLVKRFGMD 239 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 M+DP L ++A + KT AQ+++R+ +D + IPK+V+ R+ N ++ DFKL Sbjct: 240 LPGPKMDDPVLTSLAKKYEKTPAQIVLRWLVDRKVVPIPKTVSPKRLLENINIFDFKLKE 299 Query: 156 EDVALIDSFDCGGRLVPMTASLGHKHHPFE 67 E++ I+ F+ R + H +PF+ Sbjct: 300 EEIEKINQFNSNTRYTLPSFWQKHPFYPFD 329 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 149 bits (360), Expect = 9e-35 Identities = 84/201 (41%), Positives = 112/201 (55%), Gaps = 3/201 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVS 520 YLDLYLIHWP +G+ LFP G D D TW ME ++K+G K+IG+S Sbjct: 132 YLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLS 191 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 N +E +++ V P VNQVE HPY Q L ++C+ +G+ + AYSPLGS P Sbjct: 192 NAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGSTSSP--- 248 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 L EDP L A+A + A VLI YQ++ G +V+PKSVT +RI SN + KL Sbjct: 249 -----LHEDPDLLAVAKKHNVPTATVLISYQVNRGVVVLPKSVTPARIESNLKTI--KLD 301 Query: 159 REDVALIDSFDCGGRLVPMTA 97 ED+ +D GG+ TA Sbjct: 302 EEDMNKLDKLAEGGKQTRFTA 322 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 148 bits (358), Expect = 2e-34 Identities = 81/190 (42%), Positives = 111/190 (58%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++YLDLY+IH P L ++G+ + +TW+ ME LV+EGLVKSIGVSN Sbjct: 102 LEYLDLYIIHIP--------LTADKKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSN 153 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN K+LE LL A ++P VNQ E H Y + +L +FC+ + IT Y PLG+P Sbjct: 154 FNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQFCKKHNIHITGYCPLGNPG---ISS 210 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 P E+ +KAIA + K AQ+ I++ I SG+ VIPKSV RI N +V DF+L Sbjct: 211 GVPAPFENEVVKAIAKKHNKKAAQICIKFSIASGHSVIPKSVHEERIKENGEVFDFELDE 270 Query: 156 EDVALIDSFD 127 ED+ + D Sbjct: 271 EDMEKLRGLD 280 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 147 bits (357), Expect = 2e-34 Identities = 75/186 (40%), Positives = 103/186 (55%), Gaps = 2/186 (1%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 N+ YLDLYL+HWP A+K + FP + + +T AM K+GL+K +GVS Sbjct: 100 NLDYLDLYLMHWPVAFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVS 159 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP--W 346 NF+ ++LE L P +NQVE HPYL Q L +C G+ +T YSPLGS DR Sbjct: 160 NFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLGSGDRSEGM 219 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 D+P L ED +K +A+R + Q LI + G VIPKS RI N + + + Sbjct: 220 KADDEPSLFEDDTIKKVAERNNISKGQTLIAWAKQRGTAVIPKSTNEGRIKENLESDNIE 279 Query: 165 LSREDV 148 LS+ED+ Sbjct: 280 LSKEDL 285 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 147 bits (355), Expect = 3e-34 Identities = 82/225 (36%), Positives = 127/225 (56%), Gaps = 14/225 (6%) Frame = -3 Query: 696 VQYLDLYLIHWPQA--YKEDGSLFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIG 526 +QYLD+YLIH P A +KED T++ G + + D + WK ME VKEG KSIG Sbjct: 127 LQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIG 186 Query: 525 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD--- 355 +SNFN Q+ +L+ A +KP QVE H Y QK L EFC+ G+ +T Y+PLGSP Sbjct: 187 LSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSPGARK 246 Query: 354 --RPWAKPDD-PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF 184 P ++ P + + P + IA + GK+V Q+L+ + + G VI S + + N Sbjct: 247 ELHPGQMEEEFPDVFKLPVVNEIAKKHGKSVVQILLHHLVQKGIAVIFSSKNPNHLKENI 306 Query: 183 DVLDFKLSREDVALIDSFDCG--GRLVPMTASLG---HKHHPFEN 64 ++ DF+L+ +++ +D+ D G G++ G H+++PF + Sbjct: 307 EIFDFELTEDEMKSLDALDKGERGKIFDYKFLKGIEKHQYYPFSS 351 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 147 bits (355), Expect = 3e-34 Identities = 81/196 (41%), Positives = 115/196 (58%), Gaps = 2/196 (1%) Frame = -3 Query: 687 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 508 +DLYLIHWP PT G D+V TWK +E G ++SIGVSNF Sbjct: 110 IDLYLIHWP---------LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQV 153 Query: 507 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDP 328 L+RL Q ATV P VNQ+E HPY + ++ C + + A+SP+ Sbjct: 154 NHLQRLAQEATVVPAVNQIEVHPYFGNEEVRRHCGEHQIGVEAWSPIAQG---------- 203 Query: 327 QLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDV 148 ++++DP + A+A+RLGK+ AQV++R+ ++ G+IV PKSVT SR+ NF + DF+L+ ED+ Sbjct: 204 KVLDDPTVTAVANRLGKSPAQVVLRWHVERGDIVFPKSVTPSRMEENFALFDFELTEEDL 263 Query: 147 ALIDSFDCG--GRLVP 106 ALI + D G GR P Sbjct: 264 ALISALDKGEAGRTGP 279 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 146 bits (354), Expect = 5e-34 Identities = 75/199 (37%), Positives = 118/199 (59%), Gaps = 7/199 (3%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL L+H+P +K FP D G++ + +VDTW+A+E +VK G V++IGVSNF+ Sbjct: 132 YVDLLLMHYPCTFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFS 191 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD-----RPW 346 ++E LL+ + P V+Q+E HPYL QK E+ +G+ + +SPLG+ + W Sbjct: 192 KGEIETLLRETSTVPAVHQMEVHPYLQQKGFNEWLREKGIHVVQFSPLGNMNDFYRQAGW 251 Query: 345 AK--PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLD 172 +K ++++ P LK I + GK+ QV++ + I+SG VIPK+V +I N D Sbjct: 252 SKEIAHMMRVIDQPILKEIGQKYGKSPVQVVLAWGINSGRSVIPKTVIDWQIEENL-AAD 310 Query: 171 FKLSREDVALIDSFDCGGR 115 F+L ED+A I + D R Sbjct: 311 FELDAEDMARIATLDAKAR 329 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 146 bits (353), Expect = 6e-34 Identities = 75/196 (38%), Positives = 119/196 (60%), Gaps = 6/196 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYK----EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 529 + Y+DL+LIH P A+K +DG++ P D+ GKIQ+ +D ++T+ AME K+GL + I Sbjct: 94 LSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHI 153 Query: 528 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 GVSNF+ +QLER+ + +KP NQVEC+ Y K L +CE+ + + A++ +G P P Sbjct: 154 GVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLLSYCESHNIYLMAHTTIGHP--P 211 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRY--QIDSGNIVIPKSVTRSRIASNFDVL 175 P L+EDP +K +A KT AQ+ +++ Q I+IP S+ I SN++ L Sbjct: 212 LKGPFGTSLLEDPVVKQVASEAKKTSAQICLKFLQQKSKMYILIPMSMNPKNIKSNYE-L 270 Query: 174 DFKLSREDVALIDSFD 127 DF L+ + + ++ D Sbjct: 271 DFTLTEQQMKKLEELD 286 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 145 bits (352), Expect = 8e-34 Identities = 81/197 (41%), Positives = 120/197 (60%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP GK + Y DTW+A+E L K+G +++IGVSN Sbjct: 103 LDYLDLYLIHWP---------------GKDK-----YKDTWRALEKLYKDGKIRAIGVSN 142 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F LE LL+ A +KP+VNQVE HP L QK L+++C+A+G+++ A+SPL Sbjct: 143 FQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKAQGIQLEAWSPL---------- 192 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 QL+++ L IA++ K+VAQV++R+ + + IPKS+ RI N D+ DF+LS+ Sbjct: 193 MQGQLLDNEVLTQIAEKHNKSVAQVILRWDLQHEVVTIPKSIKEHRIIENADIFDFELSQ 252 Query: 156 EDVALIDSFDCGGRLVP 106 ED+ ID+ + R+ P Sbjct: 253 EDMDKIDALNKDERVGP 269 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 145 bits (352), Expect = 8e-34 Identities = 81/203 (39%), Positives = 117/203 (57%), Gaps = 2/203 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLD YLIHWP ++K FP D+ G + + +TWKAME L++ G V+ IG+SN Sbjct: 109 LDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSN 168 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN LER+L+ A VKP V+Q+E HP+L Q E + G+ +TAYSP G+ + + + Sbjct: 169 FNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTIY-ES 227 Query: 336 DDPQLMEDPKLKAIADRLGK--TVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 P+L+E ++ IA G+ T A + + + I G VIPKSV RI SNF + L Sbjct: 228 KIPKLIEHETIQKIAKSKGEGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFKYI--PL 285 Query: 162 SREDVALIDSFDCGGRLVPMTAS 94 ++ED+ I+S R T S Sbjct: 286 TKEDMDEINSIGIRARFNQATFS 308 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 144 bits (348), Expect = 2e-33 Identities = 78/215 (36%), Positives = 130/215 (60%), Gaps = 7/215 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGV 523 ++YLDLYLIH P +++ G L P D++G I+ + ++V+ W ME VK G K+IG+ Sbjct: 103 LEYLDLYLIHVPIGFEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGL 162 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD--RP 349 SNFN Q++R+L++ +K + Q+E H Y QK L +FC+ + ITAYSPLGS + Sbjct: 163 SNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSPLGSRSLIKL 222 Query: 348 WAKPDD-PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLD 172 K ++ ++++ + IA + K+ AQ+L+RY + +G +VIPKS+ RI N + D Sbjct: 223 LNKTEEISDMLQNDVVMEIAKKYKKSSAQILLRYIVQNGIVVIPKSINPQRIKENIQLFD 282 Query: 171 FKLSREDVALIDSFDCG--GRLVPMTASLGHKHHP 73 ++++ ED+ + + D G R+ + G + HP Sbjct: 283 WEINPEDMKKLYNLDRGESSRICDLKFFKGIETHP 317 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 143 bits (347), Expect = 3e-33 Identities = 80/218 (36%), Positives = 123/218 (56%), Gaps = 10/218 (4%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPT--DQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIG 526 ++Y+++YLIH P A+ +D + + G + +D D+V W+AME VK G V+SIG Sbjct: 124 LEYVNMYLIHKPFAFVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIG 183 Query: 525 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRP 349 +SNFN QL + +HA +KP Q+E Y Q+ ++E C R + +TA+S LGSP P Sbjct: 184 LSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLGSPGSSP 243 Query: 348 WAK----PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFD 181 K P L + P +K IA+ +T AQVL+R+ + +G IV+PKS RI N Sbjct: 244 DKKTRYIKSLPTLFDHPIVKKIAEAHNRTSAQVLLRHAVQNGIIVLPKSTNPGRIKQNIG 303 Query: 180 VLDFKLSREDVALIDSFDCG--GRLVPMTASLGHKHHP 73 + DF L+ +++ ++ D G GR+ G + HP Sbjct: 304 IFDFALTEDEMQAMNGLDKGEKGRIFHFFIDKGVEKHP 341 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 143 bits (347), Expect = 3e-33 Identities = 81/190 (42%), Positives = 113/190 (59%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP A + ++ K Q ++ DTW AME L K+G +K++GVSN Sbjct: 99 LDYLDLYLIHWPAAAHQF-------ENWK-QLNN----DTWSAMEKLYKDGKIKALGVSN 146 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L LLQHAT+KP VNQ+E HP Q+ +FC +++ +SPLG D Sbjct: 147 FMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQVEGWSPLGRGD------ 200 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + ++ LK +A + KTVAQ+ IR+ I + I +PKSVT +RI NF+V DF +S Sbjct: 201 ----VFDNEVLKQLAHKYNKTVAQLSIRWAIQNNVIPLPKSVTPNRIIENFEVSDFNISE 256 Query: 156 EDVALIDSFD 127 D+ALI+ D Sbjct: 257 SDMALINKID 266 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 143 bits (347), Expect = 3e-33 Identities = 85/214 (39%), Positives = 122/214 (57%), Gaps = 6/214 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDV---DYVDTWKAMEPLVKEGLVKSI 529 V Y+DL+L+HWP A +++ GK + + TW+AME LV G+VK+I Sbjct: 115 VDYIDLFLVHWPIAAEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAI 174 Query: 528 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 GVSN+ L++LL+ A +KP VNQ+E HP+L L EFC + AYSPLGS ++ Sbjct: 175 GVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGSQNQ- 233 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 ++ ++P L A+ADR G ++AQVL+ + + G +V+PKS T SRI SNF + + Sbjct: 234 -VPTTGERVRDNPTLNAVADRRGSSLAQVLLAWGLKRGYVVLPKSSTPSRIESNFIIPE- 291 Query: 168 KLSREDVALIDSFDCGG--RLVPMTASLGHKHHP 73 LS ED A I G R V M + G+ P Sbjct: 292 -LSEEDFAAIQKVAEGRHVRFVNMKDTFGYDVWP 324 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 142 bits (345), Expect = 6e-33 Identities = 74/182 (40%), Positives = 112/182 (61%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++YLDLYLIHWP + + FP + + F D W++ME K GL K+IGVSN Sbjct: 112 LEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLGLTKAIGVSN 168 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ K+L+ LL AT++PVV+QVE + QK+L+EFC+ G+ +TA+SPL R A Sbjct: 169 FSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPL----RKGASR 224 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++ME+ LK IA+ GK++AQV +R+ + G +PKS + R+ N + D+ L+ Sbjct: 225 GPNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKSYDKERMNQNLHIFDWALTE 284 Query: 156 ED 151 +D Sbjct: 285 QD 286 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 142 bits (344), Expect = 7e-33 Identities = 81/190 (42%), Positives = 111/190 (58%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V Y+DLYLIHWP D L Y+DTW+A+E L ++G K+IGVSN Sbjct: 97 VDYVDLYLIHWPMP---DEDL---------------YMDTWRALEQLYRDGKAKAIGVSN 138 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ L R+L+ TV P VNQ+E HP+L+Q+ ++ FC+ G+ + A+SPL K Sbjct: 139 FHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSPL-------MKG 191 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 D + DP + IA R GKT AQV++R+ + I IPKSVT SRI N D+ DF LS Sbjct: 192 RD--ALTDPVITDIAARHGKTPAQVVLRWHLQHDIIAIPKSVTPSRIQENLDIFDFVLSP 249 Query: 156 EDVALIDSFD 127 +D+ ID + Sbjct: 250 DDMRQIDQLN 259 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 142 bits (344), Expect = 7e-33 Identities = 74/186 (39%), Positives = 110/186 (59%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYLIHWP + D L K D TWKAME + GL KSIG+ N Sbjct: 110 MEYVDLYLIHWPVRLRHD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICN 167 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 + +K+L +LL+ AT+ P VNQVE +P Q L+EFC+ +G+ ++A+SPLG+ W Sbjct: 168 YGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGAYKIFWG-- 225 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +ME+ L+ IA GKT+AQV +R+ G+ + KS + R+ N ++ DF+LS Sbjct: 226 -SGAVMENQILQDIATAKGKTIAQVALRWVYQQGSSAMAKSFNKERMKQNLEIFDFELSE 284 Query: 156 EDVALI 139 E++ I Sbjct: 285 EELEKI 290 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 142 bits (343), Expect = 1e-32 Identities = 83/195 (42%), Positives = 112/195 (57%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++YLDLYLIHWP KE YVDT+KA E L+ +G V++IGVSN Sbjct: 101 LEYLDLYLIHWPMPAKER------------------YVDTYKAFEKLLADGRVRAIGVSN 142 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + LERL +V P VNQ+E HP+L Q +E +G+ A+SPLGS Sbjct: 143 FLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREVHAEQGIATEAWSPLGS-------- 194 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +++ P + AIA + G+T AQV++R+ + GN+VIPKSVT SRI N DV F L Sbjct: 195 -GKGILDIPAIVAIAQKHGRTPAQVVLRWHLQLGNVVIPKSVTPSRIKENIDVFGFSLDT 253 Query: 156 EDVALIDSFDCGGRL 112 ED+A I + + RL Sbjct: 254 EDLAAISALNEDRRL 268 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 142 bits (343), Expect = 1e-32 Identities = 79/197 (40%), Positives = 111/197 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIHWP P DQ YV W+ + L KEGL++SIGVSN Sbjct: 98 LDYVDLYLIHWPAP--------PQDQ----------YVGAWQQLIELQKEGLIRSIGVSN 139 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + ++RL+ V PV+NQ+E HP L Q++L + + ++SPL Sbjct: 140 FQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSPLAQGGE----- 194 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + ++ ++ + + GKT AQV+IR+ ID+G IVIPKS T SRI NFDV DFKL + Sbjct: 195 ---NVFDNQLVQHLTQKYGKTPAQVVIRWHIDNGMIVIPKSTTLSRIKENFDVFDFKLEK 251 Query: 156 EDVALIDSFDCGGRLVP 106 ED+ + + D G RL P Sbjct: 252 EDLTAMTTLDIGKRLGP 268 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 141 bits (341), Expect = 2e-32 Identities = 77/198 (38%), Positives = 113/198 (57%), Gaps = 2/198 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 + Y+DLYLIHWP + DG++ + K D V WK ME LV GL KSIG+ Sbjct: 102 MDYVDLYLIHWPVTFDPAPDGTVESCGK--KYNVGKFDAVGVWKKMEALVDLGLAKSIGI 159 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SNF E++L + P Q+E HPYLNQK L EF +++G+++ +YS LGS A Sbjct: 160 SNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGS-----A 214 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 ++ +D +KAIA + G +Q+++ Y G VIPKS ++ + N D+ + L Sbjct: 215 PGSSAKVRDDKTIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEHLRENIDLKE--L 272 Query: 162 SREDVALIDSFDCGGRLV 109 SRED++ ID+ + G R V Sbjct: 273 SREDISAIDALNTGHRYV 290 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 141 bits (341), Expect = 2e-32 Identities = 82/192 (42%), Positives = 111/192 (57%), Gaps = 3/192 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIG 526 + Y+DLYL+HWP +G+ FP G ++VDTWK ME L G K++G Sbjct: 101 LDYVDLYLVHWPILMNPEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVG 160 Query: 525 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW 346 VSN++ LE+LL HAT P VNQVE HP L Q+ L +FC+ +G+ I AYSPLGS Sbjct: 161 VSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGS----- 215 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 P L +P +K IA++ + A VL+ YQI G VIPKSV RI +N + D Sbjct: 216 --TGGPLLTAEPVVK-IAEKHSISPAAVLLGYQIARGITVIPKSVNPDRIKANAQLKD-- 270 Query: 165 LSREDVALIDSF 130 L ED+ L++ + Sbjct: 271 LDAEDMKLLNDY 282 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 140 bits (339), Expect = 3e-32 Identities = 85/192 (44%), Positives = 106/192 (55%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYLIHWP KI YVDTWKA+ + +GL +SIGVSN Sbjct: 155 LEYVDLYLIHWPVP--------------KID----RYVDTWKALAKIKADGLARSIGVSN 196 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L+RL + PVVNQVE HP L Q L+ F + A+SPLG Sbjct: 197 FTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAWSPLG--------- 247 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 L+ DP L IA + G++ AQV+IR+ I G +VIPKSVT SRIA N +V DF L Sbjct: 248 -QGTLLADPVLAGIAQKHGRSAAQVIIRWHIQQGLVVIPKSVTPSRIAENANVFDFTLDA 306 Query: 156 EDVALIDSFDCG 121 ED+A I S D G Sbjct: 307 EDMAAIASLDAG 318 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 140 bits (339), Expect = 3e-32 Identities = 83/213 (38%), Positives = 116/213 (54%), Gaps = 3/213 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF 514 Y+DL++IH P A K+ G L P D SG+I V+ DTW+ L K GL Sbjct: 113 YVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL--------- 163 Query: 513 NSKQLERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAK 340 KP NQV ECHPYLNQ +L EFC+++ + + AYS LGS P W Sbjct: 164 ------------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVD 211 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 PD P L+E+P LK+IA + ++ QV +RYQ+ G +V+ KS ++ RI NF + DF+L+ Sbjct: 212 PDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELT 271 Query: 159 REDVALIDSFDCGGRLVPMTASLGHKHHPFENE 61 ED+ ID + R + + H + PF E Sbjct: 272 PEDMKAIDGLN---RNLRYDNAANHPYFPFSEE 301 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 140 bits (338), Expect = 4e-32 Identities = 74/190 (38%), Positives = 111/190 (58%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLD YL+HWP K G P + + + D+ +TW+ ME ++ GL +SIGVSN Sbjct: 103 LDYLDNYLVHWPIKLKP-GVSEPIPKEDEFE-KDLGIEETWQGMERCLEMGLCRSIGVSN 160 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+SK++ LL A+V P VNQVE HP Q++L++ CE + ++ YSPLG P W Sbjct: 161 FSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPGNCWG-- 218 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++E P +K+IA + T AQV +R+ + G VI KS +R+ N L+ KL Sbjct: 219 -STAVIEHPIIKSIALKHNATPAQVALRWGMSKGASVIVKSFNGARMIENKRALEIKLDD 277 Query: 156 EDVALIDSFD 127 +D++LID + Sbjct: 278 QDLSLIDHLE 287 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 139 bits (337), Expect = 5e-32 Identities = 76/205 (37%), Positives = 119/205 (58%), Gaps = 3/205 (1%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 NV Y+D+YL+H P + L + WKA+E V G +K+IGVS Sbjct: 114 NVDYMDMYLMHSPGTMGAEKRL-----------------EAWKALEEAVDAGKIKTIGVS 156 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NF+ ++L+ LL + +KP VNQ+E HP+ + L+E C +RG+ I AYSP+ Sbjct: 157 NFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREACISRGIHIQAYSPMA-------- 208 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 Q ++ P++K IA + GKT AQ+L+++ + GNI++PKS+T+ RI SN + DF+L Sbjct: 209 --QGQALDRPEIKTIASKHGKTPAQILLKWGLTHGNIILPKSLTKHRIESNAQLFDFELD 266 Query: 159 REDVALIDSFDCG---GRLVPMTAS 94 +D+ ++D+ D G G+L P S Sbjct: 267 SDDMDVLDNLDEGMKVGKLGPAGTS 291 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 139 bits (336), Expect = 7e-32 Identities = 73/209 (34%), Positives = 111/209 (53%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYL+H P A + + + + W +E +EGL +SIGVSN Sbjct: 107 MDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSN 166 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN Q+ LL A++ P VNQ+EC NQ+ +++FC+ + + + Y+PLG P+ Sbjct: 167 FNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILVMGYTPLGKQKLPF--- 223 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +++ +LK IA + KT AQV +RY ID G + I KS R R N D+ DFKL++ Sbjct: 224 -----LQNNRLKEIALSVDKTTAQVSLRYLIDEGVVPIVKSTDRKRQQENLDIFDFKLTK 278 Query: 156 EDVALIDSFDCGGRLVPMTASLGHKHHPF 70 + + +D+ R M G KH PF Sbjct: 279 QQLEELDAIGGDQRACKMDFLAGAKHFPF 307 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 139 bits (336), Expect = 7e-32 Identities = 75/188 (39%), Positives = 107/188 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLY IHWP K DG+ P + ++F D WK ME LVK+GLVK IGV N Sbjct: 112 LDYIDLYHIHWPFRLK-DGAHMPPEAGEVLEF---DMEGVWKEMENLVKDGLVKDIGVCN 167 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 + +L RLL+ A + P V Q+E HP ++ E C+ G+ +TAYSPLGS ++ Sbjct: 168 YTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSPLGSSEK----- 222 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 L DP ++ +A++L KT QVLI++ + G VIPKS RI N V +++ Sbjct: 223 ---NLAHDPVVEKVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPE 279 Query: 156 EDVALIDS 133 ED ++ S Sbjct: 280 EDFKVLCS 287 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 138 bits (335), Expect = 9e-32 Identities = 75/194 (38%), Positives = 111/194 (57%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDL+LIHWP +D Y++++KA+E L +EG +K+IGV N Sbjct: 99 LDYLDLFLIHWPCE------------------NDQLYIESYKALEHLYEEGKIKAIGVCN 140 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F LE+L++ + P VNQ+E HPY NQ+ +++FC+ +K+TA+ PL Sbjct: 141 FKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWMPL---------M 191 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + L++DP + IA R KT AQ+++R+ + I+IPKS T RI NFD+ DF L Sbjct: 192 RNKGLLDDPVITDIAHRYDKTPAQIVLRWHLAHNRIIIPKSQTPKRIKENFDIFDFNLEL 251 Query: 156 EDVALIDSFDCGGR 115 DVA IDS + R Sbjct: 252 TDVAEIDSLNKNAR 265 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 138 bits (333), Expect = 2e-31 Identities = 66/182 (36%), Positives = 106/182 (58%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DL L+HWP FP + D++ V W+ ME + GL ++IGVSN Sbjct: 111 MDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGV--WRGMEECHRLGLARAIGVSN 168 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F++K+LE+LL A V+P NQVE +P Q+ L+E C GV++ YSPLG+ PW Sbjct: 169 FSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSPLGAKGTPWG-- 226 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +M+ L IA GKT+AQ+ +R+ + G++++ K+ +R+ N D+ D++L+ Sbjct: 227 -SAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLLVKTYNENRMKENLDIFDWELTE 285 Query: 156 ED 151 E+ Sbjct: 286 EE 287 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 137 bits (331), Expect = 3e-31 Identities = 77/195 (39%), Positives = 110/195 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V+Y+DLYLIHWP + Y++TW+A E L + V++IGVSN Sbjct: 101 VEYVDLYLIHWPGPNRS-------------------YIETWRAFEKLYEMKKVRAIGVSN 141 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L+ LL + TV P+VNQVE HP+ QK L+ +C + + +TA+ PLG Sbjct: 142 FEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAYCAEKNIAVTAWRPLGK-------- 193 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 L+ +P+L +A++ ++ AQV+IR+ I G I IPKS RI NFDV DF+LS Sbjct: 194 --GALLTEPQLVELAEKHKRSAAQVIIRWLIQLGVIAIPKSSHEERIKQNFDVFDFELSP 251 Query: 156 EDVALIDSFDCGGRL 112 ED+ I+S D R+ Sbjct: 252 EDMRRIESMDRNSRI 266 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 136 bits (328), Expect = 6e-31 Identities = 81/203 (39%), Positives = 117/203 (57%), Gaps = 7/203 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAY--KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 ++YLDL L+HW A+ +ED P D++GKI ++D ++TWKAME GL K IGV Sbjct: 95 LEYLDLVLVHWACAFQSREDDEYLPRDETGKIITENIDILETWKAMEECYNLGLAKHIGV 154 Query: 522 SNFNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 SNF+ +QLER+ VK P NQVE H YL Q+ + ++ R + + +Y+ LG R Sbjct: 155 SNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRKMYMISYTCLG---RA 211 Query: 348 WAK-PDDPQLMEDPKLKAIADRLGKTVAQVLIRY--QIDSGNIVIPKSVTRSRIASNFDV 178 K P L++DP L +A +GKT AQ +R+ ++ +VIPKS+ + I N Sbjct: 212 TLKGPYGYPLLQDPVLNEVAKEIGKTPAQTNLRFLLKLSPYAVVIPKSLNPANIKGNIS- 270 Query: 177 LDFKLSREDVALIDSFDCGGRLV 109 LDF L++E + S CG R V Sbjct: 271 LDFDLTQEQFEKLRSRQCGWRFV 293 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 135 bits (327), Expect = 9e-31 Identities = 66/182 (36%), Positives = 109/182 (59%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DL L+HWP + FP + + D++ V W+ ME + GL ++IGVSN Sbjct: 109 MDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGV--WRGMEECHRLGLARAIGVSN 166 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F++K+LE+LL A V+P VNQVE +P Q+ L+E C GV++ YSPLG+ PW Sbjct: 167 FSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLGAKGTPWG-- 224 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +M+ L+ IA GKT+AQ+ +R+ + G++++ K+ R+ N D+ +++L+ Sbjct: 225 -SAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLLVKTYNEKRMKENLDIFNWELTD 283 Query: 156 ED 151 E+ Sbjct: 284 EE 285 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 135 bits (326), Expect = 1e-30 Identities = 73/192 (38%), Positives = 112/192 (58%), Gaps = 1/192 (0%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 N++YLD LIHWP K L P D ++ +I+ ++TWKA+ L K G++K IGV Sbjct: 110 NIKYLDCVLIHWPGVSK----LPPNDPKNAQIR------LETWKALIELRKAGVIKHIGV 159 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SNFN L+ L++ + KP +NQ E HP K+ EFC+ G+ + AYSPL Sbjct: 160 SNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEFCQKNGILVEAYSPLAR------ 213 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 ++M+ P + +A + KTVAQV++R+ + + ++IPKS T RI N D+LDF L Sbjct: 214 --QHEKVMKHPLINQLAQKYKKTVAQVILRWALQNNMVIIPKSKTPQRIQENIDILDFAL 271 Query: 162 SREDVALIDSFD 127 S +++ ++ D Sbjct: 272 SPQELEQMNQLD 283 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 135 bits (326), Expect = 1e-30 Identities = 74/197 (37%), Positives = 110/197 (55%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIHWP K+D YV W+ + L ++GL++SIGV N Sbjct: 98 LDYVDLYLIHWPDP-KQD-----------------HYVSAWRELVTLKEQGLIRSIGVCN 139 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ L+RL+ + P VNQ+E HP L Q++L + + ++SPL + Sbjct: 140 FHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWSPLAQGGKG---- 195 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + + ++ +A + KT AQ++IR+ +DSG IVIPKSVT +RI NF+V DFKL + Sbjct: 196 ----VFDQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVIPKSVTPARIRENFEVFDFKLQK 251 Query: 156 EDVALIDSFDCGGRLVP 106 E++ I DCG RL P Sbjct: 252 EELLAITKLDCGKRLGP 268 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 134 bits (325), Expect = 1e-30 Identities = 68/162 (41%), Positives = 99/162 (61%) Frame = -3 Query: 576 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEAR 397 ++A+E L+ +G V++IGVSNF + L RLL ++ P VNQ+E HPY Q+ L+ Sbjct: 137 YRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEH 196 Query: 396 GVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPK 217 G+ A+SP+G + + + +EDP L IA + GK+ AQV++R+ + G VIPK Sbjct: 197 GILTQAWSPIGGIT--FYRGGEKSTLEDPVLLEIAQQHGKSAAQVMLRWHLQEGRSVIPK 254 Query: 216 SVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRLVPMTASL 91 S +RIA NFDV DF+LS E +A ID+ D G R P S+ Sbjct: 255 STKPARIAENFDVFDFELSGEQIAAIDALDTGVRSGPEPDSI 296 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 134 bits (325), Expect = 1e-30 Identities = 78/190 (41%), Positives = 107/190 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIH P+A E+G P D +D ++TW ME K GL KSIGVSN Sbjct: 125 LSYVDLYLIHSPEATNENGD--PVD---------IDVLNTWNGMEEAKKLGLAKSIGVSN 173 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F++ L+RL+ + P VNQ+E HP Q++L RG+++ AYSP G Sbjct: 174 FDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPFGFYVSR-GSH 232 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++P + D + IA + KTV QVL+RY ++ I IPKS + RI N DV DF+LS Sbjct: 233 NNP-VKNDRTVADIARKYNKTVNQVLVRYLLERSLIPIPKSTNQQRIRENIDVFDFQLSP 291 Query: 156 EDVALIDSFD 127 ED+ I D Sbjct: 292 EDINAIGKLD 301 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 134 bits (323), Expect = 3e-30 Identities = 73/199 (36%), Positives = 116/199 (58%), Gaps = 9/199 (4%) Frame = -3 Query: 696 VQYLDLYLIHWPQA--YKEDGSLFPT---DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 532 + Y DL+++H+P A Y + +P ++ K++FS+ +TW AME LV + L +S Sbjct: 103 LDYFDLFIVHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARS 162 Query: 531 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYS---PLGS 361 IGVSNF+++ L LL++A ++P Q+E HPYL Q+RL + + G+ +TAYS PL Sbjct: 163 IGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPLSF 222 Query: 360 PDRPWAKP-DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF 184 + + P+L + +K IA + GKT AQVL+R+ VIPKS +R+A N Sbjct: 223 VELDLKDAHETPKLFDHDVIKGIAQKHGKTPAQVLLRWATQRNIAVIPKSNDPTRLAQNL 282 Query: 183 DVLDFKLSREDVALIDSFD 127 DV + L ++ +I S + Sbjct: 283 DVTGWDLETSEIEVISSLN 301 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 133 bits (322), Expect = 3e-30 Identities = 76/187 (40%), Positives = 117/187 (62%), Gaps = 6/187 (3%) Frame = -3 Query: 690 YLDLYLIHWPQAY-KEDGSLFPTDQSG---KIQFSDV--DYVDTWKAMEPLVKEGLVKSI 529 YLDLYL+HWP A+ GS+ P+ +S ++ D+ D++ T++ ME +VK+G V++I Sbjct: 107 YLDLYLMHWPVAFLNSKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNI 166 Query: 528 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 GVSNFN ++ ++ A++KPVVNQVE + ++ + L+ + A GV + AYSP GS ++ Sbjct: 167 GVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPFGS-NQN 225 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 AK +EDP + +A R T AQVL+ + + I I KSVT RI NF VLD Sbjct: 226 VAKS-----LEDPVVVDVAQRNNITPAQVLLAWTLGRDIIPISKSVTPERIEENFRVLDI 280 Query: 168 KLSREDV 148 +L+ E++ Sbjct: 281 QLAEEEI 287 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 133 bits (322), Expect = 3e-30 Identities = 73/194 (37%), Positives = 105/194 (54%), Gaps = 4/194 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYV----DTWKAMEPLVKEGLVKSI 529 + YLDLYL+H+P K + G+ + D+D TW+ ME V GLV+SI Sbjct: 99 IDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSI 158 Query: 528 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 G+SN+ L ++ +KP V+Q E HPY + L +FC GV TA++PLG Sbjct: 159 GLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAAN 218 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 ++DP L +A + GK+VAQ+ +R+ I VIPKS R+ N +VL+F Sbjct: 219 KDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKTAVIPKSSKIQRLKENLEVLEF 278 Query: 168 KLSREDVALIDSFD 127 +LS ED+ LI S D Sbjct: 279 QLSDEDMQLIYSID 292 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 132 bits (320), Expect = 6e-30 Identities = 66/153 (43%), Positives = 93/153 (60%) Frame = -3 Query: 585 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFC 406 V +W+AM L +GL +SIGVSNFN LE L +H+ + PVVNQ+E HPYL + L +FC Sbjct: 117 VGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFC 176 Query: 405 EARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIV 226 + I AYSPL ++ + DP L+++ D+ GKT AQVL+R+ + G I Sbjct: 177 RKHSIAIQAYSPLTRGEK----------LHDPLLRSLGDKYGKTPAQVLLRWSLQKGYIC 226 Query: 225 IPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 I KSV SRI N DV +F +S D+ ++D + Sbjct: 227 ISKSVQLSRIIENVDVFNFTISMADMEILDGLE 259 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 132 bits (319), Expect = 8e-30 Identities = 75/188 (39%), Positives = 111/188 (59%), Gaps = 1/188 (0%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + YLDLYLIHWP A + L + + K++ V TW + L ++GL++SIGVS Sbjct: 124 DTSYLDLYLIHWPGASR---ILENSPDNPKLR------VTTWATLVELQQKGLLRSIGVS 174 Query: 519 NFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 N+ LE LL+H + VKP VNQVECHP+ Q L EFC +G+ + AYS LG+ Sbjct: 175 NYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYSSLGT------ 228 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 D L+EDP +K IA L + A+VL+++ + G +IPK++ I N LDF++ Sbjct: 229 -SDTTNLLEDPVVKKIASELNVSPARVLLKWALQRGLGIIPKAIKSDHIKDNIK-LDFEI 286 Query: 162 SREDVALI 139 S++ + L+ Sbjct: 287 SKDQMTLL 294 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 131 bits (317), Expect = 1e-29 Identities = 73/196 (37%), Positives = 108/196 (55%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++YLDLYLIHWP +E S P ++G + D D W+ ME L K+ LV++IGV N Sbjct: 139 LEYLDLYLIHWPIRLREGASKPP--KAGDVL--DFDMEGVWREMENLSKDSLVRNIGVCN 194 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F +L +LL A + P V Q+E HP R+ EFC+ + +TAYSPLGS + Sbjct: 195 FTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPLGSQE------ 248 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 L+ D + IA +L KT Q+L+++ + G VIPKS+ RI N V D+ + Sbjct: 249 GGRDLIHDQTVDRIAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKVFDWVIPE 308 Query: 156 EDVALIDSFDCGGRLV 109 +D ++S R++ Sbjct: 309 QDFQALNSITDQKRVI 324 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 131 bits (316), Expect = 2e-29 Identities = 75/187 (40%), Positives = 104/187 (55%) Frame = -3 Query: 687 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 508 LDLYLIHWP + YV+TWKA+ L K G VKSIGVSNF S Sbjct: 106 LDLYLIHWPMP------------------AQGQYVETWKALVELKKSGRVKSIGVSNFES 147 Query: 507 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDP 328 + LER++ V PVVNQ+E HP Q+ L+EF E ++ ++ PLG Sbjct: 148 EHLERIMDATGVVPVVNQIELHPDFQQRALREFHEKHNIRTESWRPLGK----------G 197 Query: 327 QLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDV 148 +++ D ++ IA++ +T AQV+IR+ + +G IVIPKSV R+A N DV F L +D+ Sbjct: 198 RVLSDERIGKIAEKHSRTPAQVVIRWHLQNGLIVIPKSVNPKRLAENLDVFGFVLDADDM 257 Query: 147 ALIDSFD 127 I+ D Sbjct: 258 QAIEQMD 264 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 131 bits (316), Expect = 2e-29 Identities = 71/167 (42%), Positives = 103/167 (61%), Gaps = 4/167 (2%) Frame = -3 Query: 672 IHWPQAYKEDG-SLFPTDQ-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 499 IHWP A++ +L P D S + + +++ DTW A+E LV G V+SIGVSNF +++ Sbjct: 128 IHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIEKI 187 Query: 498 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKI--TAYSPLGSPDRPWAKPDDPQ 325 E LL+ A + P VNQ+E HPYL Q L ++ + + I AYSPLG+ + P+ Sbjct: 188 EELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPLGNNIY-----NAPR 242 Query: 324 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF 184 +++DP +K IA +L K A +LI + + G V+PKSVT SRI SNF Sbjct: 243 VVDDPTVKEIAQKLNKDPAALLISWAVQRGTSVLPKSVTPSRIESNF 289 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 130 bits (315), Expect = 2e-29 Identities = 65/174 (37%), Positives = 104/174 (59%), Gaps = 1/174 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVS 520 + YLDLYLIH P A++ P DQ+G + + + V +TW A+E LV G ++IG+S Sbjct: 109 LDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLS 168 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 + + +L + + A +KP V QVE HPYL + L EFC+ G+ + A++PLG R Sbjct: 169 DISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAPLGHGMR---- 224 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDV 178 P L+EDP + ++++R+GKT AQVL+ + + G ++ + +R NFD+ Sbjct: 225 ---PGLLEDPVITSVSERVGKTAAQVLLSWAVQRGTALLTTPRSAARAKENFDI 275 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 130 bits (315), Expect = 2e-29 Identities = 72/192 (37%), Positives = 107/192 (55%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+D+YLIHWP + K +P K F +DY W+AME K GL K+IGVSN Sbjct: 110 LEYIDMYLIHWPVSSKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIGVSN 166 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ K+L +L +A V P VNQVE +P QK+L EFC++ G+ + AY+ LG+ + Sbjct: 167 FSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAALGAVGTFYG-- 224 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++M L IA G TVAQV +R+ + G V+ KS + R+ N + ++ LS Sbjct: 225 -TNRVMGSEVLNEIARIRGNTVAQVCLRWAYEQGIGVLVKSFNKERMEQNLQIFNWTLSD 283 Query: 156 EDVALIDSFDCG 121 ++ I G Sbjct: 284 DESKKISEIPQG 295 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 128 bits (310), Expect = 1e-28 Identities = 77/197 (39%), Positives = 111/197 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP + Y ++W+A+E L EG VK+IGVSN Sbjct: 106 LDYLDLYLIHWP--------------------GNNSYKESWQALETLYAEGKVKAIGVSN 145 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F LE LL +A V PV+NQVE HP L+QK +++FCE +K+ A+SPL Sbjct: 146 FQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAWSPL---------- 195 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 QL+ + + AIA+ K+ AQV++R+ I ++ KSV + R+ SN V DF+LS Sbjct: 196 MQGQLLSNETILAIAENHNKSAAQVILRWDIQQDILLAVKSVHKERMISNAAVFDFELSA 255 Query: 156 EDVALIDSFDCGGRLVP 106 E++A I+ + R+ P Sbjct: 256 EEMAQINQLNESLRVGP 272 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 128 bits (310), Expect = 1e-28 Identities = 65/147 (44%), Positives = 91/147 (61%), Gaps = 2/147 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYK--EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 ++YLDLYLIH+P + + ED + + +D WK ME + GL K+IGV Sbjct: 107 MEYLDLYLIHFPVSMRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRLGLTKAIGV 163 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SNF+ K+LE LL AT+ P NQVE HPY Q +L+EFC+ +G+++ AYSPLG PW+ Sbjct: 164 SNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLGGKGTPWS 223 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQV 262 + +M+ P LK IA GKT+AQ+ Sbjct: 224 ---NNAVMDCPLLKQIAMERGKTIAQI 247 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 128 bits (310), Expect = 1e-28 Identities = 74/190 (38%), Positives = 105/190 (55%), Gaps = 3/190 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIG 526 + Y+D+ LIHWP +G+ ++P G + TWK ME ++K G KSIG Sbjct: 129 LDYVDMLLIHWPVPLNPNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIG 188 Query: 525 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW 346 VSNF+ LE LL+ A V P VNQVE HP L Q L EFC+ + +TA+SP GS P Sbjct: 189 VSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSVGGP- 247 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 L+++ + ++AD+ + +L Y I +G +VIPKSVT SRI N Sbjct: 248 -------LLKNELVVSLADKYNTSPGGILTSYHIGNGTVVIPKSVTNSRIVEN-GKSAVT 299 Query: 165 LSREDVALID 136 LS+ED+ ++ Sbjct: 300 LSQEDLKALN 309 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 128 bits (310), Expect = 1e-28 Identities = 73/196 (37%), Positives = 113/196 (57%), Gaps = 2/196 (1%) Frame = -3 Query: 693 QYLDLYLIHWPQ-AYKEDGSLFPTDQSGKIQFSDVDYV-DTWKAMEPLVKEGLVKSIGVS 520 +Y+DLYL+H+PQ + ++ + FP + G I+ + + D W +E L+ G VK+IGVS Sbjct: 103 EYIDLYLVHFPQRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVS 162 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 N++ K LE LL+ A V P VNQVE HP+L Q +L +C+ +G+ +TAY+P G Sbjct: 163 NYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTGY------- 215 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 ++ DP + +A + G + AQ+++ + + G PKS SR N + L F L Sbjct: 216 ---QTVLTDPTIVELAGKYGVSPAQIVLAWHLSRGVAAAPKSANESRQKENLN-LPF-LQ 270 Query: 159 REDVALIDSFDCGGRL 112 EDVA I + D G R+ Sbjct: 271 PEDVAKISALDRGQRI 286 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 128 bits (308), Expect = 2e-28 Identities = 70/197 (35%), Positives = 104/197 (52%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP Y+D+W+AME L K G +K+IGVSN Sbjct: 108 LDYLDLYLIHWPAP---------------------GYLDSWRAMEDLYKAGKIKNIGVSN 146 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN Q+ +L H TVKPVV+Q+E HPY Q + + E++G+ A+SPLG + Sbjct: 147 FNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAYLESQGILHEAWSPLGGGNN----- 201 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + D + +A + AQ+++R+ + +VIPKS+ +RI N D+ F L Sbjct: 202 ---NALTDSVINELAAAHDVSAAQIILRWHVQREEVVIPKSIHEARIQQNRDIFAFGLDE 258 Query: 156 EDVALIDSFDCGGRLVP 106 +++ I D G R+ P Sbjct: 259 DEMKAISDLDTGKRVGP 275 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 128 bits (308), Expect = 2e-28 Identities = 74/193 (38%), Positives = 111/193 (57%), Gaps = 3/193 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL-VKSIGVS 520 ++Y+DLYLIHWP + D + + D D+VDTW+ ++ + KEG VK+IGVS Sbjct: 104 LEYVDLYLIHWPLS---------VDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVS 154 Query: 519 NFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW 346 NFN K+L++LL + V PV+NQ+E HP L Q L ++ +++ + ITAYSPLG Sbjct: 155 NFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLGHA---- 210 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 D +++ + IA + QVLI + + G IVIPKS T RI N + F Sbjct: 211 ----DASTLKNKVVTDIAKKHNANAGQVLISWGVQRGTIVIPKSTTDERIIDN--IKTFT 264 Query: 165 LSREDVALIDSFD 127 LS+ED +++ + Sbjct: 265 LSQEDFDALNNLE 277 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 127 bits (307), Expect = 2e-28 Identities = 69/190 (36%), Positives = 112/190 (58%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP ++D L +DTW+ +E L ++ V++IGVSN Sbjct: 97 LDYLDLYLIHWPN--EDDFELT---------------LDTWRVLETLYQQKKVRAIGVSN 139 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ QL+++ + ATVKP++NQ+E HPY Q L +F + YSP+G Sbjct: 140 FSEDQLKQVFEMATVKPMINQIERHPYKVQADLGQFDTDNDIVNEGYSPIG--------- 190 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++EDP + +A++ GK+ AQ+++R+QID+G +V PKS +R+ NF++ F L+ Sbjct: 191 HGHLILEDPVITKLAEKYGKSPAQIVLRWQIDTGFVVFPKSSKPARVKENFEISGFSLTA 250 Query: 156 EDVALIDSFD 127 +++A I+ D Sbjct: 251 DEIAEINGLD 260 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 127 bits (306), Expect = 3e-28 Identities = 77/197 (39%), Positives = 109/197 (55%), Gaps = 10/197 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYK----EDGSLFPTDQSGKIQFSDVD----YVDTWKAMEPLVKEGL 541 + Y+ LYL+HWP + +DG+LF + DVD ++ TW+ M+ L++ G Sbjct: 102 LDYVGLYLVHWPVPLRTENIKDGNLFQFAEKPDGS-KDVDLEWNFIKTWELMQKLLESGK 160 Query: 540 VKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 367 K+IGVSNF+ L+ LL T K P VNQVE HP L Q+ L ++C +G+ I AYSPL Sbjct: 161 TKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPL 220 Query: 366 GSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 187 G + P ++ DP ++ IA G V+I + + G + +PKSVT SRI N Sbjct: 221 GGENAP--------ILSDPTVQEIAKANGVEAGHVVISWAVQKGLVTLPKSVTPSRIVGN 272 Query: 186 FDVLDFKLSREDVALID 136 VL LS DVA +D Sbjct: 273 LKVL--TLSDSDVAKVD 287 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 126 bits (305), Expect = 4e-28 Identities = 72/190 (37%), Positives = 106/190 (55%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + ++DLYLIH+P K +D+WK +E L + L K+IGVSN Sbjct: 106 IDFVDLYLIHFPVTSKR--------------------MDSWKELEKLYHDKLCKAIGVSN 145 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 + L LL+++ + P VNQVE HP+LNQ L E+C+ +++ AYSPL Sbjct: 146 YTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQLEAYSPLA--------- 196 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 Q +EDP + IA + KT AQ+LIR+ I+ +VIPKS+ + RI N V DF +S Sbjct: 197 -HGQKIEDPTIAKIAQKYDKTPAQILIRWAIEQKIVVIPKSIKKERIIENSKVFDFAISE 255 Query: 156 EDVALIDSFD 127 ED+ +++S D Sbjct: 256 EDMKILNSLD 265 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 126 bits (304), Expect = 5e-28 Identities = 74/214 (34%), Positives = 113/214 (52%), Gaps = 7/214 (3%) Frame = -3 Query: 690 YLDLYLIHWPQAYKE-DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF 514 Y+DLYL+H+P + D D+ +D+ + W+AME + G K+IG+SNF Sbjct: 119 YVDLYLVHYPCGILDTDRERLSADEVTVDPTTDIHAI--WRAMEAQLAAGKTKNIGLSNF 176 Query: 513 NSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPD 334 N+ Q++R+++ V+P V QVE H Y+ Q L+ FC + + A+ PLG P R K Sbjct: 177 NADQVQRIIKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPFRLIRKAS 236 Query: 333 DP----QLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 P L+EDP++ +A KT AQVL+RY I IPKS +R+ N + DF+ Sbjct: 237 RPGEVKLLLEDPQVLDVATAHHKTPAQVLLRYLHQINVIPIPKSANPTRLFQNTQIFDFE 296 Query: 165 LSREDVALIDSFDCG--GRLVPMTASLGHKHHPF 70 L+ +++ + D G GR+ H H F Sbjct: 297 LTSAEMSRLAGLDRGHEGRIFTEFRRGDHTHPEF 330 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 126 bits (304), Expect = 5e-28 Identities = 70/148 (47%), Positives = 93/148 (62%), Gaps = 1/148 (0%) Frame = -3 Query: 579 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEA 400 TWKAME LV +G K IGVSNF++ +L+RLL + PVVNQVE +PY QK+L FC Sbjct: 145 TWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHE 204 Query: 399 RGVKITAYSPLGSPDRPW-AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVI 223 + +TAY PLG P+ P +ED +KA+A+R +T AQ+++ + I G VI Sbjct: 205 HEIHVTAYGPLGCTPVPYLIGRKTPGPLEDCTVKAMAERYSRTPAQIILAHLIMLGVSVI 264 Query: 222 PKSVTRSRIASNFDVLDFKLSREDVALI 139 PKS SRI+ NFD L +LS ED A + Sbjct: 265 PKSNNLSRISENFDCL-VELSPEDHAAL 291 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 126 bits (303), Expect = 7e-28 Identities = 73/192 (38%), Positives = 105/192 (54%), Gaps = 2/192 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V YLDLYLIHWP A+K G++ D I + W +E V +GLV+ IGVSN Sbjct: 105 VGYLDLYLIHWPVAWKR-GTVLQPDAEASI-------AECWSELERCVADGLVRHIGVSN 156 Query: 516 FNSKQLERLLQ--HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 FN QL L ++P NQ+E HP + L ++ +++G+ +TAYSPL Sbjct: 157 FNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKYSQSKGLTVTAYSPLAQGG---- 212 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 +L E+ L +A + G T AQV++R+ + +VIPKS + RIASN D+ F+L Sbjct: 213 -----ELFENEILVGLAKKYGVTPAQVVLRWNVQRDVVVIPKSTSAKRIASNADLFGFEL 267 Query: 162 SREDVALIDSFD 127 S ED+ + D Sbjct: 268 SDEDMDAMKVLD 279 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 126 bits (303), Expect = 7e-28 Identities = 72/213 (33%), Positives = 117/213 (54%), Gaps = 10/213 (4%) Frame = -3 Query: 696 VQYLDLYLIHWP--QAYKEDGSLFPTD----QSGKIQFSDVDYVDTWKAMEPLVKEGLVK 535 ++Y DLYLIH+P Y + +P + + K+ F + W ME LV+ L + Sbjct: 104 LEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHECWAEMEKLVQAKLTR 163 Query: 534 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP- 358 +IGV+NFN + + LL +A +KP V Q+E HP L Q+RL ++ + +G+++TAYS G Sbjct: 164 NIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQGIQVTAYSSFGPTS 223 Query: 357 --DRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF 184 D + L+ + +K+IA++ Q+L+RY +D VIPKSV R+ SN Sbjct: 224 YVDLCESGKTYSSLLANADVKSIANKHNANTGQILLRYALDRNIAVIPKSVHEDRMKSNL 283 Query: 183 DVLDFKLSREDVALIDSFDCGGRL-VPMTASLG 88 D+L+ +L ++D +++S R PM G Sbjct: 284 DILNIQLDQDDRKILNSLKTNQRFNDPMIFGFG 316 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 125 bits (302), Expect = 9e-28 Identities = 73/202 (36%), Positives = 115/202 (56%), Gaps = 12/202 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQA--YKEDGSLFPT----DQSGKIQFSDVDYV---DTWKAMEPLVKEG 544 + Y+DLYL+H+P A Y + +P D S + ++D V +TW AME LV+ G Sbjct: 106 LDYIDLYLVHFPIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESG 165 Query: 543 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 364 LV+ IGV N+++ L L+ +A +KP + Q+E HPYL Q+ L + + +TA+SPLG Sbjct: 166 LVRQIGVCNYSAVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLG 225 Query: 363 S---PDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIA 193 S + A +D ++ DP + A A R G T AQV++R+ I G VIPK+ R+ Sbjct: 226 SLSYVELNMAGAND-TVLTDPSVLAAAQRNGVTAAQVVLRWGIQRGTAVIPKTSNPQRLI 284 Query: 192 SNFDVLDFKLSREDVALIDSFD 127 N + +F L+ E++ I + + Sbjct: 285 ENLTLTEFTLNDEEMDAISALN 306 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 125 bits (301), Expect = 1e-27 Identities = 74/213 (34%), Positives = 115/213 (53%), Gaps = 23/213 (10%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVD-TWKAMEPLVKEGLVKSIGVS 520 V YLDLYL+HWP + P SG ++ + WKAME L++ GLV++IGVS Sbjct: 108 VTYLDLYLMHWPDITAFGDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVS 167 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP------ 358 NF +Q++ LL+ A + P VNQV+ HP+ Q L +FC+++G+ ++A++PLG P Sbjct: 168 NFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTPLGVPASGPGP 227 Query: 357 -DRPWAKPDDP----------QLMEDPKLK-----AIADRLGKTVAQVLIRYQIDSGNIV 226 D D+P + + P LK IADR KT QV++R+ + G V Sbjct: 228 SDSGSGGEDEPGTPRISFRRSRSVHGPMLKLSVVAEIADRHKKTPEQVILRWGLQRGTSV 287 Query: 225 IPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 +P S+ RI N D+ + LS ++ ++ + Sbjct: 288 LPCSLKADRIRKNIDIFSWSLSDDECNCLNQIE 320 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 124 bits (300), Expect = 2e-27 Identities = 76/198 (38%), Positives = 110/198 (55%), Gaps = 12/198 (6%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDV------DYVDTWKAMEPLVKEGLVK 535 + YLDLYL+HWP ++ LFP + ++ DV VDTWKAM L K + Sbjct: 105 LDYLDLYLVHWPVSFTTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPKSK-AR 163 Query: 534 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 355 ++GVSN LE ++ V P VNQ+E HP L L E+C+ +G+ +TAYS G+ Sbjct: 164 TVGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGNNG 223 Query: 354 RPWAKPDDPQLMEDPKLKAIAD----RLGKTV--AQVLIRYQIDSGNIVIPKSVTRSRIA 193 P L+ P++K +A+ RLG TV AQV++ + G+ VIPKSVT SRI Sbjct: 224 F-----GVPLLVTRPEVKEVAESASKRLGTTVTPAQVILAWSQVGGHSVIPKSVTPSRIH 278 Query: 192 SNFDVLDFKLSREDVALI 139 NF + +L+ E++A + Sbjct: 279 ENFK--EVELTPEEIAKV 294 >UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 282 Score = 124 bits (299), Expect = 2e-27 Identities = 65/157 (41%), Positives = 95/157 (60%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 D V ++ +E KEG +++IG+SNF+ Q +R+L V P +NQVECHPY Q LK Sbjct: 108 DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECHPYFPQTELKA 167 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 + + + A+ PLG + +D +M +P ++ +A+ K+ AQVL+R+ I G+ Sbjct: 168 LLKDHNITLQAWYPLG------GRGND-SIMSEPIVQGLAEEHSKSPAQVLLRWHIQQGH 220 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 IVIP S T S IA N D+ DF L+ ED+A IDS D G Sbjct: 221 IVIPGSKTPSHIAQNIDLFDFALTDEDMAQIDSLDKG 257 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 124 bits (299), Expect = 2e-27 Identities = 71/195 (36%), Positives = 107/195 (54%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 NV+YLD+YLIH+ +Y Y++TW AME L +G +K IGV+ Sbjct: 101 NVEYLDMYLIHFASSY---------------------YLETWHAMEELYLQGKIKVIGVA 139 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NF + LE L++H+ + P++NQ+E HP Q L ++ + A++PLG ++ Sbjct: 140 NFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAPLGQGNK---- 195 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 L+E+ LK IA KTVAQV++R+ I G I+IPKS RI N + DF+LS Sbjct: 196 ----ALLENTVLKKIASNHEKTVAQVILRWHIQRGIIIIPKSSNPKRIKENIQLFDFELS 251 Query: 159 REDVALIDSFDCGGR 115 E++ I+ + G R Sbjct: 252 SEEMEKINQLNTGKR 266 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 124 bits (299), Expect = 2e-27 Identities = 73/201 (36%), Positives = 108/201 (53%), Gaps = 11/201 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYL H P + K+DGS SDV D W+ E + GL K+IGVSN Sbjct: 105 LDYVDLYLAHIPASTKDDGSFR----------SDVKVEDIWRGFEKVYGLGLTKAIGVSN 154 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP------- 358 FN Q+ R++ V +Q+E H YL QK +E C+ + ITAY+ LGSP Sbjct: 155 FNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGRMSVVG 214 Query: 357 --DRPW--AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIAS 190 RP + + M D +KA+A + KT AQ+L+R ++ G IVIPK+ R+ Sbjct: 215 SNGRPLFESTQNSENEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTNPERMKE 274 Query: 189 NFDVLDFKLSREDVALIDSFD 127 N ++ DF +S +V L+++ + Sbjct: 275 NINIFDFNISNAEVNLLEAHE 295 >UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative; n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase (GCY1), putative - Aspergillus fumigatus (Sartorya fumigata) Length = 274 Score = 124 bits (298), Expect = 3e-27 Identities = 68/159 (42%), Positives = 97/159 (61%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 DY +TW+ ME + K G VK+IGV+N++ LE L + TV P VNQVE HP+L Q LKE Sbjct: 106 DY-ETWRQMEEIYKAGKVKAIGVANWSIPYLEELKKKWTVVPAVNQVELHPFLPQHALKE 164 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 +C+ G+ + AYSPLGS P LM DP ++ +A + G + A VLI Y ++ G Sbjct: 165 WCDKHGILLEAYSPLGSEGAP--------LMSDPAIQEMAKKYGVSPATVLISYHVNRGV 216 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGR 115 +V+PKS +RI SN V+ LS ED+ +++ G+ Sbjct: 217 VVLPKSTQENRILSNRQVI--PLSPEDMDVLNGLAAQGK 253 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 123 bits (297), Expect = 4e-27 Identities = 73/190 (38%), Positives = 107/190 (56%), Gaps = 4/190 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAY-KED--GSLFPTDQS-GKIQFSDVDYVDTWKAMEPLVKEGLVKSI 529 + Y+DL+LIHWP A K+D G L D S G + F D W+ ME + GL +SI Sbjct: 122 LDYVDLFLIHWPVAIGKKDAAGELTWDDLSRGLVPF---DMEGVWRGMEECHRLGLARSI 178 Query: 528 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 GVSNF++ ++ RLL A V P VNQVE + Q++++E C GV + AYSPLG+ Sbjct: 179 GVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLGAHGAH 238 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 W +M L +A KT+AQV +R+ + G ++ +S R+ N D+ D+ Sbjct: 239 WG---SDAVMNSGVLHDVAAARCKTIAQVALRWLYEQGVCMVARSFNEGRMKQNMDIFDW 295 Query: 168 KLSREDVALI 139 +LS +D A+I Sbjct: 296 ELSDQDKAMI 305 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 123 bits (297), Expect = 4e-27 Identities = 74/198 (37%), Positives = 110/198 (55%), Gaps = 10/198 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQ----AY--KEDGSLFPTDQSGK--IQFSDVDYVDTWKAMEPLVKEGL 541 + Y+DLYL+HWP AY ED PT + G + ++ +++ TW+ M+ L K G Sbjct: 103 LDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGK 162 Query: 540 VKSIGVSNFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 367 K++GVSNF+ L+ LL Q + P NQVE HP L Q L FC+++G+ + AYSPL Sbjct: 163 TKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPL 222 Query: 366 GSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 187 GS D P L+++P + IA + V+I + + G +V+PKSV RI +N Sbjct: 223 GSTDAP--------LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTN 274 Query: 186 FDVLDFKLSREDVALIDS 133 + F LS ED I++ Sbjct: 275 RKI--FTLSTEDFEAINN 290 >UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Os05g0456200 protein - Oryza sativa subsp. japonica (Rice) Length = 229 Score = 123 bits (296), Expect = 5e-27 Identities = 61/132 (46%), Positives = 85/132 (64%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 D TW+AME L G ++IGVSNF+ K+LE LL A V P VNQVECHP Q +L++ Sbjct: 76 DIPATWQAMEKLYDSGKARAIGVSNFSCKKLEDLLNVARVPPAVNQVECHPVWQQGKLRK 135 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 C+++GV ++AY+PLGSP P D P ++ P + +IA +L K+ AQV +R+ I G Sbjct: 136 LCQSKGVHLSAYAPLGSPGSP--GNDGPNVLSHPTVISIAKKLQKSPAQVALRWGIQMGQ 193 Query: 231 IVIPKSVTRSRI 196 V+PKS R+ Sbjct: 194 SVLPKSDNEVRL 205 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 123 bits (296), Expect = 5e-27 Identities = 60/156 (38%), Positives = 101/156 (64%), Gaps = 1/156 (0%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ-HATVKPVVNQVECHPYLNQKRLK 415 D +++WKA+E V+EG +++IGVSNF ++ LL H + P VNQ+E HP+ +Q+++ Sbjct: 116 DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVV 175 Query: 414 EFCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSG 235 ++CE++G+++ AY+PL ++ + +L AIA + K+ AQ++IRY + G Sbjct: 176 DYCESKGIQLAAYAPLVHGEK----------FGNKQLLAIASKYNKSEAQIMIRYCLQRG 225 Query: 234 NIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 IV+PKS T RI N DV DF++S+ED+ + + D Sbjct: 226 FIVLPKSSTPRRIKENGDVFDFEISKEDMEKLYNLD 261 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 122 bits (294), Expect = 9e-27 Identities = 73/201 (36%), Positives = 118/201 (58%), Gaps = 12/201 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKE-------DGSL-FPTDQSGKIQFS-DVDYVDTWKAMEPLV--- 553 ++Y+DL L HWP +++ G + P D SGK ++ D DY++T+K +E + Sbjct: 122 LEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDP 181 Query: 552 KEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYS 373 + V++IGVSNF+ + LERL++ VKP VNQVE HP+L Q L++FC + +TAYS Sbjct: 182 NDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYS 241 Query: 372 PLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIA 193 PLGS P ++ P +K +A++ T +LI Y I G IVIP+S+ RI+ Sbjct: 242 PLGSHGAP--------NLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRIS 293 Query: 192 SNFDVLDFKLSREDVALIDSF 130 S+ + L+++++ ++ F Sbjct: 294 SSIEFA--SLTKDELQELNDF 312 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 121 bits (292), Expect = 1e-26 Identities = 67/186 (36%), Positives = 106/186 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP K+ G D + KI +TW+AME L EG +++IGVSN Sbjct: 104 MDYLDLYLIHWPANEKQFG-----DDAAKIN------AETWRAMEDLYNEGKIRAIGVSN 152 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + L++ A V P V+Q+E HP + ++ +A + + A++PLG Sbjct: 153 FMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWAPLGG-------- 204 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +++ +P + IAD+ KT AQV +R+ + G + +PKSV + R+ SN ++ DF+L+ Sbjct: 205 QGAKVLTNPTMIQIADKYQKTPAQVCLRWVLQQGILPLPKSVHKERMISNQNIFDFELTD 264 Query: 156 EDVALI 139 ED+ I Sbjct: 265 EDMRKI 270 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 121 bits (292), Expect = 1e-26 Identities = 63/155 (40%), Positives = 92/155 (59%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 +Y W A+E VK G VKSIG+SNF+ ++L L A +KP QVE HPY QK L+E Sbjct: 111 NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQKELQE 170 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 F + G KI ++ PLG D+ +L+++ +LK IA + KTVAQ+++R+ I G Sbjct: 171 FLKPYGTKIESWYPLGHGDQ--------RLLDESRLKKIAQKYNKTVAQIILRWHIQEGI 222 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 IV P+S +A N ++ DF+LS ++ I D Sbjct: 223 IVFPRSTRVEHLAENINIFDFELSCTEIKEIRKLD 257 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 121 bits (292), Expect = 1e-26 Identities = 69/197 (35%), Positives = 104/197 (52%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIHWP GK Y+D+W + ++G+ +SIGV N Sbjct: 107 LDYVDLYLIHWPAG-----------DHGK-------YIDSWGGLMKAKQDGVARSIGVCN 148 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN++ L ++ + P +NQ+E HP LNQ L+E G+ AY PLG Sbjct: 149 FNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREVNAGYGIVTEAYGPLGV-------- 200 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +L++ + +A GKT AQVL+R+ I GN+VI +S RI SN +V DF+L+ Sbjct: 201 --GRLLDHAAVTGVAQAHGKTPAQVLLRWSIQLGNVVIARSANPDRITSNLEVFDFELTD 258 Query: 156 EDVALIDSFDCGGRLVP 106 +++A ++ D G R P Sbjct: 259 DEMATLNGLDEGTRFRP 275 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 121 bits (292), Expect = 1e-26 Identities = 67/161 (41%), Positives = 100/161 (62%), Gaps = 5/161 (3%) Frame = -3 Query: 585 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKE 412 ++TWKA++ V G+VKSIGVSNF ++ L + KP+VNQ+E P+L +K L + Sbjct: 128 IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSPWLMRKDLVD 187 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 +C+ G+ + AY PL + AK +DP L++ +A + KT AQVL+R+ ID G Sbjct: 188 YCQNLGIVLEAYCPLTTG----AKLNDPTLVK------LAKKYNKTPAQVLLRWNIDRGV 237 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALI---DSFDCGG 118 +VIPKS+ R+ NFD+ DFKL+ ED A + D++D G Sbjct: 238 VVIPKSLKPERLPQNFDLFDFKLTDEDFAELAHPDAYDVFG 278 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 121 bits (291), Expect = 2e-26 Identities = 76/211 (36%), Positives = 114/211 (54%), Gaps = 17/211 (8%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYK--------EDGSLFPTD--QSGKIQFSDVDYVDTWKAMEPLVKE 547 + YLDLY IH+P A+K G D + G I + V +DT++A+E V E Sbjct: 102 LDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDE 161 Query: 546 GLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 367 GL+KSIGVSNF ++ LL+ +KPV Q+E HPYL Q+ L EFC+ +++ AYS Sbjct: 162 GLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSF 221 Query: 366 G-----SPDRPWAKPDDPQLMEDPKLKAIA-DRLGKTVAQVLIRYQIDSGNIVIPKSVTR 205 G D AK P L E+ +K ++ + G T +QVL+R+ G VIPKS + Sbjct: 222 GPQSFIEMDLQLAK-TTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKK 280 Query: 204 SRIASNFDV-LDFKLSREDVALIDSFDCGGR 115 R+ N ++ F L+ +++ I + + R Sbjct: 281 ERLLGNLEIEKKFTLTEQELKDISALNANIR 311 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 120 bits (290), Expect = 3e-26 Identities = 69/194 (35%), Positives = 110/194 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYLIHWP A + LF ++++AME L +EG +++IGVSN Sbjct: 117 MEYVDLYLIHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGVSN 158 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F LE LL+ A V P VNQ+E HP+L Q L++ + G++ A+SPLG Sbjct: 159 FQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSPLGR-------- 210 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 Q++ DP + +A ++ AQ+++R+ + GN+VIPK+ + +RI N DV F L Sbjct: 211 --GQVLADPVVLELAAAHRRSAAQIILRWHVQLGNVVIPKASSYARIRENLDVFGFTLDP 268 Query: 156 EDVALIDSFDCGGR 115 ++A + + + G R Sbjct: 269 AEMAALAALERGHR 282 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 120 bits (290), Expect = 3e-26 Identities = 72/200 (36%), Positives = 104/200 (52%), Gaps = 3/200 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYL+HWP D + IQ +WKA E ++ +G ++IGV N Sbjct: 101 LDYVDLYLLHWPTK----------DWNATIQ--------SWKAAEKILGDGRARAIGVCN 142 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F QL+ L+ + V P VNQ+E HPY QK L A G+ A+SP+G Sbjct: 143 FLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALGIVTEAWSPIGGAINDGDGD 202 Query: 336 DD---PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 + + DP + IA+ G++ AQV++R+ + + IPKSV RIA N DV DF Sbjct: 203 NHGGRKHPLTDPVITTIAEAHGRSAAQVILRWHFQNDVVAIPKSVNPERIAKNIDVFDFA 262 Query: 165 LSREDVALIDSFDCGGRLVP 106 LS ++A +D D G R+ P Sbjct: 263 LSDAEMAQLDELDTGVRIGP 282 >UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus clavatus Length = 283 Score = 120 bits (289), Expect = 3e-26 Identities = 65/155 (41%), Positives = 98/155 (63%), Gaps = 1/155 (0%) Frame = -3 Query: 582 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFC 406 + W+A+E L++EG KSIGVSNF K +E + +A V P VNQ+E HP+ Q+ + +C Sbjct: 127 ELWQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYC 186 Query: 405 EARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIV 226 + G+ + AYSPL R + K +DP L++ +A + GKT AQVLIRY + + Sbjct: 187 KRNGIVVEAYSPLV---RNY-KANDPTLVD------LAKKYGKTTAQVLIRYALQKHWVP 236 Query: 225 IPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 +PKS T RI +N V DF++S ED+A++++ D G Sbjct: 237 LPKSDTPERIEANTKVFDFEISEEDMAVLNALDQG 271 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 120 bits (288), Expect = 5e-26 Identities = 70/193 (36%), Positives = 101/193 (52%) Frame = -3 Query: 693 QYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF 514 +Y+DLYLIHWP +G L P D + S+ +W +E G K+IGVSN+ Sbjct: 104 EYIDLYLIHWPGM---EG-LDPEDS----RHSEYR-AQSWATLEEFHASGQFKAIGVSNY 154 Query: 513 NSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPD 334 +K + LL V P V Q+EC P L Q+ L++ C G+ AYS LG Sbjct: 155 TAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLCMETGIHFQAYSSLGK--------- 205 Query: 333 DPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRE 154 L+ +P++ I G+T AQVL+R+ + G V+P+S SR+ N V DFKL+ Sbjct: 206 -GALLREPEVMDIVRHCGRTPAQVLLRWALQQGISVLPRSSQPSRVLENAQVFDFKLNET 264 Query: 153 DVALIDSFDCGGR 115 D+ +D +CG R Sbjct: 265 DMKRLDDLNCGTR 277 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 119 bits (287), Expect = 6e-26 Identities = 67/193 (34%), Positives = 105/193 (54%), Gaps = 6/193 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD---VDYVDTWKAMEPLV---KEGLVK 535 + Y+DL+L+HWPQ + +D F T +S ++ + +TW ME + +G VK Sbjct: 104 IDYIDLWLLHWPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVK 163 Query: 534 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 355 +IGVSNF+ K LE L + + V P VNQ+E HPYL + L ++C+ + + +TAYSPLG Sbjct: 164 AIGVSNFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLGQ-- 221 Query: 354 RPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVL 175 + + ED L IA + T A V + + + G V PKS R+ N ++ Sbjct: 222 ------YNASIHEDKDLNEIAKKHDVTAATVALSWAVQRGTSVAPKSTNEKRMKQNITLI 275 Query: 174 DFKLSREDVALID 136 KL+ E++ +D Sbjct: 276 --KLTDEEMKQVD 286 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 119 bits (286), Expect = 8e-26 Identities = 73/197 (37%), Positives = 107/197 (54%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V+ LDL LIHWP + D+ Y++TWKA + + EGL++SIG SN Sbjct: 100 VEQLDLVLIHWP-----------------VPSQDL-YLETWKAFQDMRDEGLMRSIGTSN 141 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN+ LER++ PV+NQ+E +P L Q ++ +A GV A++PLG+ Sbjct: 142 FNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGNA------- 194 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +P KA+A R GK+ QV++R+ + GN VIP+SV R A N DV DF L+ Sbjct: 195 --RSFEAEPITKAVA-RTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAENLDVFDFTLTE 251 Query: 156 EDVALIDSFDCGGRLVP 106 +++ I + D G R P Sbjct: 252 AEMSEIATLDMGLRTGP 268 >UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 293 Score = 119 bits (286), Expect = 8e-26 Identities = 68/154 (44%), Positives = 92/154 (59%) Frame = -3 Query: 582 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 403 + W+A+ KEG VK IGVSNF L+ L P VNQ+E HP+ Q+ + ++CE Sbjct: 129 NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPPPV---PAVNQIELHPFCQQRDIVKYCE 185 Query: 402 ARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVI 223 G+ I AYSPL ++ K D ++ L +A + GK VAQVL+R+ + G I + Sbjct: 186 EHGIAIEAYSPLVRANK---KHYDNEV-----LVKVAKKYGKEVAQVLLRWSLQKGYIPL 237 Query: 222 PKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 PKSVT SRI SN D+ DFKL +ED+A ID D G Sbjct: 238 PKSVTPSRIESNADLYDFKLDQEDMAEIDGLDKG 271 >UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 274 Score = 119 bits (286), Expect = 8e-26 Identities = 68/187 (36%), Positives = 103/187 (55%), Gaps = 7/187 (3%) Frame = -3 Query: 627 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQ 454 T + K + D D+VDTW+ M+ L+ ++++GVSNF K LERLL + K P VNQ Sbjct: 93 TPEDLKKHYPDWDFVDTWREMQKLMDTNKIRNLGVSNFGIKNLERLLNDPSCKIVPAVNQ 152 Query: 453 VECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKT 274 +E HP +L +C +G+ + YSPLGS D P L ++ + +IA ++ Sbjct: 153 IELHPGNPSPKLIAYCAEKGIHCSGYSPLGSSDSP--------LYKNETIASIAKAKNRS 204 Query: 273 VAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD-----CGGRLV 109 V QVL+ + + G V+PKSV R+ +NFD+ + L+ E+VA IDS CG + Sbjct: 205 VQQVLLMWGVKKGWSVLPKSVNPDRVKANFDLDGWDLTDEEVAKIDSIPDRFKVCGDAWL 264 Query: 108 PMTASLG 88 P+ G Sbjct: 265 PIKVFFG 271 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 118 bits (283), Expect = 2e-25 Identities = 58/155 (37%), Positives = 93/155 (60%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 DY WKA+E L K+G+VK+IGVSNF + +L H VKPV+NQ+E HP + Sbjct: 112 DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLRQRIEDLH 171 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 + GV + +++ G ++ME+P L ++A++ KTV Q+++R+ I Sbjct: 172 WNNKYGVAVESWASFGRA--------TSEIMENPILVSLAEKYNKTVPQIILRWLIQQNI 223 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 +VIPK+VT SR+ N D+ DF++S +D+ LI + + Sbjct: 224 VVIPKTVTESRLKENMDIFDFEISDDDMDLIKTIN 258 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 118 bits (283), Expect = 2e-25 Identities = 73/194 (37%), Positives = 105/194 (54%), Gaps = 1/194 (0%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLDLYLIHWP Q G Y++ W+A+ K+G ++SIGVSNF Sbjct: 120 YLDLYLIHWPNP-----------QQGL-------YIEAWQALIDAQKKGYIRSIGVSNFL 161 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 K +E L + V PV+NQVE HPY NQ + + E++ + A+SPLG AK Sbjct: 162 PKHIETLRRETGVIPVINQVELHPYFNQAEQRAYDESQQIITMAWSPLGR-----AK--- 213 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 +++D LK IA +TV QV++R+Q+ G I IPK+ + +N + DF LS + Sbjct: 214 -AILDDAVLKQIAQETSRTVVQVVLRWQVQMGVIPIPKAASDQNQMANQAIFDFSLSDDQ 272 Query: 150 VALIDSFDCG-GRL 112 V I++ C GR+ Sbjct: 273 VQRINALTCADGRI 286 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 118 bits (283), Expect = 2e-25 Identities = 62/153 (40%), Positives = 88/153 (57%), Gaps = 2/153 (1%) Frame = -3 Query: 588 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 409 Y +TW+AME LV G K+IG+SNFN + +R+L+ A ++P VNQVE HPY Q L F Sbjct: 119 YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAF 178 Query: 408 CEARGVKITAYSPLGSPDRPWAKP--DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSG 235 CE + + A+ PLG P D P + D K+ IA + G T AQV++ + + G Sbjct: 179 CEKEHIHLMAHQPLGGKPVGVVAPHADIPGPLFDTKIAQIAAQTGMTPAQVILSWAVQRG 238 Query: 234 NIVIPKSVTRSRIASNFDVLDFKLSREDVALID 136 +IPK+ SR++ N + LS E A+ID Sbjct: 239 TSIIPKTSNESRLSEN--LCTAPLSEEHFAIID 269 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 117 bits (282), Expect = 2e-25 Identities = 63/190 (33%), Positives = 103/190 (54%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y DL LIHWP + +DTW A+E K G ++IG+SN Sbjct: 95 LDYFDLVLIHWPMGHD---------------------IDTWHALEAAYKAGKTRAIGISN 133 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FNS+Q L+ ++V+P+V+Q+E H +L Q ++ EF E + +YSPLG+ + Sbjct: 134 FNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPLGNGQQ----- 188 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 L+ +P LK I+++ GK+ QV++RY + + + IP+S + I SN D+ DF+L Sbjct: 189 ---NLISNPVLKEISEKYGKSPIQVILRYLVQNDVVTIPRSTNPAHIKSNIDIFDFELDN 245 Query: 156 EDVALIDSFD 127 +D+ + D Sbjct: 246 DDLKRLRVLD 255 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 117 bits (282), Expect = 2e-25 Identities = 61/155 (39%), Positives = 98/155 (63%), Gaps = 1/155 (0%) Frame = -3 Query: 582 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFC 406 + W+A+E L++EG +SIGVSNF K +E + +A V P VNQ+E HP+ Q+ ++ +C Sbjct: 127 ELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYC 186 Query: 405 EARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIV 226 + G+ + AYSPL R + K +DP L++ +A + +T AQ+LIRY + G + Sbjct: 187 KRNGIVVEAYSPLV---RNY-KANDPTLVD------VAKKYERTTAQILIRYALQKGWVP 236 Query: 225 IPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 +PKS T RI +N +V DF++ ED+A+++ D G Sbjct: 237 LPKSDTPERIVANANVFDFEIGEEDLAVLNGLDQG 271 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 117 bits (281), Expect = 3e-25 Identities = 55/154 (35%), Positives = 96/154 (62%) Frame = -3 Query: 588 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 409 Y ++W+A+E + K+G K+IGV NFN +++ LL HA +KP +NQ+E +P ++Q ++ +F Sbjct: 127 YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKF 186 Query: 408 CEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI 229 C +++ A+SPLG + +L+ + +K IAD K+ AQV++R++I G I Sbjct: 187 CRENDIQLEAWSPLG----------NGRLLSNDVIKQIADEHQKSPAQVILRWEIQQGFI 236 Query: 228 VIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 V+ K+ R+ N ++ DF LS +++ ID D Sbjct: 237 VLTKTTHPQRMKENAEIFDFTLSPDEMKQIDKLD 270 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 116 bits (280), Expect = 4e-25 Identities = 71/190 (37%), Positives = 104/190 (54%), Gaps = 2/190 (1%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYV--DTWKAMEPLVKEGLVKSIG 526 ++ Y+DLYLIHWP + I + D DTW+AME L EG +KS+G Sbjct: 96 DLNYIDLYLIHWP--------------ANAINYKDWQKTNADTWRAMEELQAEGKIKSLG 141 Query: 525 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW 346 VSNF + LE L Q A V P VNQ+E HP Q ++ EFC+ G+ + ++SPL Sbjct: 142 VSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCKNHGIAVESWSPLAR----- 196 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 ++ + L ++ + K+V+QV +R+ I I IPKS + RI N DV DF+ Sbjct: 197 -----GKVFGNDLLIGLSKKYQKSVSQVCLRWIIQHDVIAIPKSSSPERIKENIDVFDFE 251 Query: 165 LSREDVALID 136 LS+E++ I+ Sbjct: 252 LSKEEMKKIN 261 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 116 bits (279), Expect = 6e-25 Identities = 70/195 (35%), Positives = 108/195 (55%), Gaps = 1/195 (0%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 +++YLDL LIHWP G F K + +V+ TWKAME EG +K+IG+S Sbjct: 107 DLEYLDLLLIHWPI-----GKGF------KDNWQEVN-AQTWKAMEEFYLEGKIKAIGLS 154 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NF +E L + A + P+VNQ+E HP Q + E+C+ + + A+SP Sbjct: 155 NFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSPF--------- 205 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 +++E+ L +A + TVAQ+++ + I + +PKS T RI SNFDV +F ++ Sbjct: 206 -SQSKVLENKTLVQLAKKYEVTVAQLILNWIIQKDIVPLPKSKTPERIRSNFDVFNFGIN 264 Query: 159 REDVALIDSF-DCGG 118 + D+ +ID DCGG Sbjct: 265 QADLKVIDQLNDCGG 279 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 116 bits (278), Expect = 7e-25 Identities = 57/161 (35%), Positives = 90/161 (55%) Frame = -3 Query: 609 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 430 + + D + WK ME VK G +++IG+SN++ K R++Q AT+ P V Q E H Y Sbjct: 145 LHYPDQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVHIYNQ 204 Query: 429 QKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRY 250 K+ K F G ++ A+ PLG + + L DP + ++A + K+ AQVL+R+ Sbjct: 205 DKQTKAFLRNYGTQMEAWYPLGGRN-SYGNGGKDVLFADPTIVSLAKKYAKSPAQVLLRW 263 Query: 249 QIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 Q+ +GNI IP S + I N D+ DF LS +++A + D Sbjct: 264 QLQAGNIAIPGSSNPAHIRENIDIFDFALSDDEMATLSRLD 304 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 115 bits (276), Expect = 1e-24 Identities = 67/202 (33%), Positives = 107/202 (52%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 ++ Y+DLYLIHWP P++ Y++ W+ + L + G KS+GVS Sbjct: 102 SLDYVDLYLIHWPCP--------PSEL----------YINVWEVLLELKESGRAKSVGVS 143 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NF S+ ++++ + P VNQ+E HP+L Q+ L C G++I ++ P + Sbjct: 144 NFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLSCRNDGIQIESWGPFARFSK---- 199 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 L P+L A + GKT AQV++R+ I G +V PK+V R+ N D+ DF L+ Sbjct: 200 ----DLDAFPELTRPAKQYGKTPAQVILRWHIQKGYVVFPKTVHAERLRQNIDIFDFDLT 255 Query: 159 REDVALIDSFDCGGRLVPMTAS 94 ++++ IDS D G R P +S Sbjct: 256 PDEISGIDSLDAGFRTGPDPSS 277 >UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep: ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 310 Score = 115 bits (276), Expect = 1e-24 Identities = 60/153 (39%), Positives = 94/153 (61%), Gaps = 2/153 (1%) Frame = -3 Query: 579 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKEFC 406 TW+A+E V EG V+SIGVSN+ + L LL + ++PVVNQVE +P+L ++ L ++C Sbjct: 133 TWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEINPWLCRQELVQYC 192 Query: 405 EARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIV 226 + + A+SPL R ++DP L+ +A + K VAQ+L+R+ I G IV Sbjct: 193 RENNIAVQAFSPLMRGKR----------LDDPILQKVAHQYDKGVAQILVRWSIQMGFIV 242 Query: 225 IPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 +PK+ + R+A NFD+ DF+LS E ++ + D Sbjct: 243 LPKAAKKERLAPNFDIWDFELSAETMSELTHSD 275 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 114 bits (275), Expect = 2e-24 Identities = 73/197 (37%), Positives = 103/197 (52%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLDLYLIHWP A K Y D+W+AME L E L+KSIGV+N Sbjct: 103 LDYLDLYLIHWPVAGK--------------------YRDSWRAMERLHDEKLIKSIGVAN 142 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L LL A KPV+NQVE HP L Q L+++ + + A+SPL Sbjct: 143 FKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSPLAK-------- 194 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 LM++P + IA + +V QV++++ ++ I+ PKS+T SRI N + F+L Sbjct: 195 --GILMQNPVITEIAKKHQASVDQVILQWHLNRNTIIFPKSITSSRIEENSRLSYFQLDA 252 Query: 156 EDVALIDSFDCGGRLVP 106 D+ ID + G R+ P Sbjct: 253 SDMEKIDRLETGKRVGP 269 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 113 bits (273), Expect = 3e-24 Identities = 66/190 (34%), Positives = 97/190 (51%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DLYLIHWP P + + +W+ +E EG ++IGVSN+ Sbjct: 107 YIDLYLIHWPGTQG-----LPVGDKRNPE----NRAQSWRVLEEFYSEGKFRAIGVSNYT 157 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 + ++ LL+ V P V QVE HP L Q L+ C+ RGV AYS LG+ Sbjct: 158 VEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRGLCKIRGVCFQAYSSLGT---------- 207 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 L+ +P + IA G+T AQVL+R+ + V+PKS R+ N + DF++S ED Sbjct: 208 GLLLSNPVVLEIAKECGRTPAQVLLRWAVQQSIAVLPKSSQPERVKENGRLFDFEISEED 267 Query: 150 VALIDSFDCG 121 + + + DCG Sbjct: 268 MERLSALDCG 277 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 113 bits (273), Expect = 3e-24 Identities = 68/203 (33%), Positives = 102/203 (50%), Gaps = 7/203 (3%) Frame = -3 Query: 696 VQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + YLDLYLIHWP + G + + +++ TW+ +E L GLV+ IG S Sbjct: 120 LDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTS 179 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW-- 346 N +L+ LL+ A V+P VN++E HP+ Q L ++ R + Y PLGSP RP Sbjct: 180 NMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPLGSPGRPERD 239 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF----DV 178 +D +EDP ++ IA G A V +++ + G IP S R I +N V Sbjct: 240 RTAEDTSPLEDPVIQRIAAAHGMHPAAVCLKWAVQRGQTPIPFSTKRRNIHANLAAAASV 299 Query: 177 LDFKLSREDVALIDSFDCGGRLV 109 LS +++A I + D RL+ Sbjct: 300 TTAPLSEQEMADIAATDRHCRLI 322 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 113 bits (273), Expect = 3e-24 Identities = 63/188 (33%), Positives = 98/188 (52%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL LIHWP S ++ +F YV+ +E L+ EG ++SIGVSN+ Sbjct: 108 YIDLVLIHWPGT-----SRLKSNHKDNAKFRAETYVE----LETLMDEGKIRSIGVSNYE 158 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 K LE LL + P +NQ ECHP+ L E+C+ +G+ AYS LG P Sbjct: 159 IKHLETLLAECRILPAINQCECHPHFRNSELAEYCKEKGIHFQAYSSLGGPSYV------ 212 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 L++D +K IA+ + A +L+ + ++ G ++P++ RI N+ D KLS ++ Sbjct: 213 ENLLKDKIIKKIANAHSTSPAVILLAWGLNQGYSILPRTEKVGRIEENWKAKDIKLSEKE 272 Query: 150 VALIDSFD 127 + I S D Sbjct: 273 MKEIGSID 280 >UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid reductase; n=5; Pezizomycotina|Rep: Related to 2, 5-diketo-D-gluconic acid reductase - Neurospora crassa Length = 289 Score = 113 bits (273), Expect = 3e-24 Identities = 59/152 (38%), Positives = 87/152 (57%), Gaps = 1/152 (0%) Frame = -3 Query: 579 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPVVNQVECHPYLNQKRLKEFCE 403 +WKA+E V G VK GVSN+ K L+ ++ +KP+VNQ+ECHP+ Q ++ CE Sbjct: 135 SWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPLVNQIECHPFNTQPEIRAACE 194 Query: 402 ARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVI 223 G+ I AY+PL R M+ P L A+A + G T AQVL+R+ + G + + Sbjct: 195 KYGIVIEAYAPLARGMR----------MKHPVLTAVAKKYGVTPAQVLVRWSVQHGFVTL 244 Query: 222 PKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 PKS + R+ N DV F+L+ ED+ +D D Sbjct: 245 PKSTKKERLVENADVGRFELAEEDMEKLDGLD 276 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 113 bits (272), Expect = 4e-24 Identities = 69/203 (33%), Positives = 110/203 (54%), Gaps = 4/203 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 Y+DLYLI W S P T+ G + + + W+ +E V+ G+++SIGV+N Sbjct: 119 YIDLYLIQW--------SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVAN 170 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN + + LL +A +KPVVNQ+E PYL Q L F + ++ A SPLG P Sbjct: 171 FNCQMVLDLLSYAKIKPVVNQIEVTPYLPQIDLINFLKRCKIETVAISPLGRAGCFENTP 230 Query: 336 DDP--QLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 + +L+E+ K IA + K+V QV++R + ++IPK+ R+ N ++ DF+L Sbjct: 231 EGMKIKLLEEDIFKQIAQKHKKSVVQVILRCLVQREIMMIPKTAKLDRLKENSEIFDFEL 290 Query: 162 SREDVALIDSFDCGGRLVPMTAS 94 + ED+ I S + G R + + S Sbjct: 291 TEEDMKQIYSLENGTRAINLKHS 313 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 113 bits (272), Expect = 4e-24 Identities = 67/192 (34%), Positives = 104/192 (54%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYLIH P F DV WKAME + K+GLV++IGVSN Sbjct: 103 LEYIDLYLIHQP-------------------FGDVHCA--WKAMEEMYKDGLVRAIGVSN 141 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F +L L+ H + P VNQ+E HP+ ++ EF ++ A+ P + Sbjct: 142 FYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRK----- 196 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + ++ L++IA++ GKTVAQV++R+ G + IPK+V R R+ N + DF+L++ Sbjct: 197 ---NIFQNGVLRSIAEKYGKTVAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQ 253 Query: 156 EDVALIDSFDCG 121 ED+ I + D G Sbjct: 254 EDMEKIATLDEG 265 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 113 bits (272), Expect = 4e-24 Identities = 70/185 (37%), Positives = 99/185 (53%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLDL LIHWP +E + DTW+A+E L +G VKSIGVSN+ Sbjct: 106 YLDLLLIHWP--VREH------------------FFDTWRALEQLKADGQVKSIGVSNYT 145 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 LE L A PVVNQVE HPYLNQ+ L ++ + + A+SPLG Sbjct: 146 IAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVTEAWSPLGR---------- 195 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 +++DP L +A K+VAQV++R+++ + IPKS RI N ++ DF L ++ Sbjct: 196 RVVLDDPMLAKMAAHHNKSVAQVILRWELQHQLVTIPKSTHPERIQENANIFDFSLDIDE 255 Query: 150 VALID 136 + +ID Sbjct: 256 MTMID 260 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 113 bits (271), Expect = 5e-24 Identities = 67/190 (35%), Positives = 101/190 (53%), Gaps = 1/190 (0%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 N Y+DLYLIHWP A + P + TW + L K+G ++SIGVS Sbjct: 106 NTTYIDLYLIHWPGATR-----IPETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVS 156 Query: 519 NFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 NF K L+ LLQ+ + P VNQVE HP+ Q+ L ++C +G+ I AYS LG+ Sbjct: 157 NFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCNEKGIHIQAYSSLGT------ 210 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 + L+ +P + IA +L + A++L+ + + G VIPK+V + I N LDF + Sbjct: 211 -SGNINLLRNPIVLKIASQLNVSSARLLLNWALQQGIGVIPKAVNKEHIKDNIQ-LDFLI 268 Query: 162 SREDVALIDS 133 E + ++ S Sbjct: 269 DEESMNILFS 278 >UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG07276.1 - Gibberella zeae PH-1 Length = 284 Score = 112 bits (270), Expect = 7e-24 Identities = 59/153 (38%), Positives = 90/153 (58%), Gaps = 1/153 (0%) Frame = -3 Query: 576 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFCEA 400 W+AME +E ++IGVSNF + L+ + ++AT P VNQ+E HP+ QK + ++C+ Sbjct: 131 WEAMERAKREARARNIGVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQD 190 Query: 399 RGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIP 220 + I AYSPL + R +EDP ++ I+ + K+ AQVLIRY + G + +P Sbjct: 191 NEIIIEAYSPLATGAR----------LEDPLVEGISTKHDKSHAQVLIRYSLQKGWVPLP 240 Query: 219 KSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 KS RI+ NF+V DF L +D+ +D D G Sbjct: 241 KSSRPDRISENFNVFDFVLDEDDMETLDDLDKG 273 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 112 bits (270), Expect = 7e-24 Identities = 66/190 (34%), Positives = 101/190 (53%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIHWP G +++TWK ME +++ G SIGVSN Sbjct: 87 LDYIDLYLIHWPVP----GC----------------FLNTWKDMEKILESGRALSIGVSN 126 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + LE L + + + P VNQ+ECHP K L E+C+A +++ AY+PL Sbjct: 127 FEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQVQAYAPLAR-------- 178 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +++ L + + T AQ+ +R+ + G VIPKSV RIASN + DF + + Sbjct: 179 --GAYLDNDVLCVLGTKYAHTPAQIGLRWAVQKGISVIPKSVHPERIASNARIFDFTIDQ 236 Query: 156 EDVALIDSFD 127 ED+ L+D+ + Sbjct: 237 EDMDLLDTLN 246 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 112 bits (269), Expect = 9e-24 Identities = 64/172 (37%), Positives = 93/172 (54%), Gaps = 2/172 (1%) Frame = -3 Query: 696 VQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGV 523 + Y+DL L+HWP K P ++ G D TW+ ME L G K+IGV Sbjct: 132 LDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAIGV 191 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SN++ L++LL A + P NQVE HP+L Q L ++C +G+ AYSPLGS P Sbjct: 192 SNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLGSSGGP-- 249 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 187 +++D ++++IA AQV+I + G + +PKSVT SRI +N Sbjct: 250 ------VLQDERVQSIAKAHKADPAQVVISWAAQRGVVALPKSVTPSRIETN 295 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 111 bits (268), Expect = 1e-23 Identities = 63/187 (33%), Positives = 107/187 (57%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++ LDLYLIH P + E G+ + + ++ WKAME + + G ++IGVSN Sbjct: 102 LEQLDLYLIHAPWPWSEKGADYTKEN-----------IEVWKAMEEIYESGRCRAIGVSN 150 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ L+ ++++A +KP+VNQ+ Q+ + FC+ G+ + AYSPL + Sbjct: 151 FSVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILVEAYSPLAT-------- 202 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +++E+ +++ IAD+ GKT+ QV I Y + G + +PKS + I N DV DF++S Sbjct: 203 --GKILENAEIQKIADKYGKTLPQVCICYCLQKGVLPLPKSTHEAFILQNADV-DFEISS 259 Query: 156 EDVALID 136 ED+ +D Sbjct: 260 EDMQYLD 266 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 111 bits (267), Expect = 2e-23 Identities = 62/157 (39%), Positives = 89/157 (56%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 DY W+A+E +EG +K+IGVSNF L + VKP+VNQVE HPY Q Sbjct: 122 DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALA 181 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 + V+ A++PLG KP E+ L++IAD K+++QV++R+ I G Sbjct: 182 TMKYYNVQPEAWAPLGGGRH---KP-----FENNLLQSIADAHQKSISQVILRWNIQRGV 233 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 +VIPKS + RI NF + DF L+ +++A I S D G Sbjct: 234 VVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLG 270 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 111 bits (267), Expect = 2e-23 Identities = 58/138 (42%), Positives = 80/138 (57%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 DY TW AME LV +G +K IGVSNFN +LERLL A + P VNQ+E HPYL Q L Sbjct: 178 DYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVR 237 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 FC+A G+ + A+ PLG P +P A + ++ AQ+++ + + G Sbjct: 238 FCKANGIHLVAHQPLGG---------KPVAAVNPNADRPASKHERSPAQIILSWIVQQGI 288 Query: 231 IVIPKSVTRSRIASNFDV 178 VIPK+V +SR+ N D+ Sbjct: 289 SVIPKTVRQSRMVENLDL 306 >UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 302 Score = 111 bits (266), Expect = 2e-23 Identities = 61/152 (40%), Positives = 89/152 (58%), Gaps = 1/152 (0%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 D +T+ A+ LV +GLV IGVSNF+ K+L++ ++ + NQ+E HPY + L Sbjct: 123 DMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEELVR 182 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 FC+ V +TAYSPL + + +ED L++I DR GK+ AQV IR+ I N Sbjct: 183 FCQDNDVTVTAYSPLA----------EGRAVEDDVLRSIGDRYGKSAAQVSIRWLIQQEN 232 Query: 231 IV-IPKSVTRSRIASNFDVLDFKLSREDVALI 139 +V IPK+ T I +N DV DF+L+ D+ I Sbjct: 233 VVTIPKAATPKHIEANIDVFDFELTDRDMRRI 264 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 110 bits (264), Expect = 4e-23 Identities = 60/170 (35%), Positives = 96/170 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V+YLDLYLIH+P A+ ++ + ++ +DTWKAME LV+ GL ++IG SN Sbjct: 145 VEYLDLYLIHYPVAW--------VPETRDVD-NNTSLIDTWKAMEELVRAGLTRNIGFSN 195 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F K + ++L+ A+++P ++ E HPYL Q+ +F + +K+ A SPL + + P Sbjct: 196 FAPKDINKILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASPLANTN-PTYGD 254 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 187 P ++ D +A+ TVAQ ++ + G IVI KS + IA N Sbjct: 255 KYPSILHDEFWVKLAEDKNATVAQTILAWGQQRGTIVISKSTHSNHIAEN 304 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 110 bits (264), Expect = 4e-23 Identities = 66/188 (35%), Positives = 106/188 (56%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLD+YLIHWP S + +++++ ++W+AME V+ G +++IGVSN Sbjct: 104 LDYLDMYLIHWPNP-----------SSMRDHWAEIN-AESWRAMEEAVRAGKIRAIGVSN 151 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L+ L++ A +KPVVNQ+ +P Q + + + AYSPLG+ Sbjct: 152 FRKHHLDALMETAEIKPVVNQIFLNPSDLQSEVVTENKKLDLLSEAYSPLGTGG------ 205 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 L+ + +K +A GK+ AQVLIR+ + G + +PKSV I +N DV DF++S Sbjct: 206 ----LLGNEVVKEVAANYGKSTAQVLIRWSLQHGFLPLPKSVHPEYIKANADVFDFEISP 261 Query: 156 EDVALIDS 133 ED+A +D+ Sbjct: 262 EDMAKLDN 269 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 110 bits (264), Expect = 4e-23 Identities = 67/183 (36%), Positives = 98/183 (53%), Gaps = 2/183 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY-VDTWKAMEPLVKEGLVKSIGVSNF 514 YLDLYLIHWP + G +V Y +W A+ L +EG ++SIGVSN+ Sbjct: 135 YLDLYLIHWPGVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNY 194 Query: 513 NSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 K L+ +L + P VNQVE HPY Q L E+C G+ + AYS LGS Sbjct: 195 TVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLGS-------S 247 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + +L ED ++++A L KT QVL+R+ I+ ++PK+ +R I N L+F++ Sbjct: 248 NTAELREDETVQSVAKSLQKTPVQVLLRWAIEQEVGILPKARSRDHIQENVG-LEFEIPA 306 Query: 156 EDV 148 E + Sbjct: 307 EQM 309 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 110 bits (264), Expect = 4e-23 Identities = 56/152 (36%), Positives = 83/152 (54%) Frame = -3 Query: 582 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 403 + WKA+ +GLVKSIGVSNF K ++ + P VNQV+ HP++ + E CE Sbjct: 149 NVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICE 208 Query: 402 ARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVI 223 + + A+ PL R + P + IA GK AQ+++R+ I G +VI Sbjct: 209 QNEILLEAWGPLARAMR----------FDHPVVVKIAKEKGKDAAQIMLRWGIQHGFVVI 258 Query: 222 PKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 PKSV++ RI SN + DF+LS E++ +D D Sbjct: 259 PKSVSQKRIVSNSKIFDFELSSEEMKELDGLD 290 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 110 bits (264), Expect = 4e-23 Identities = 69/192 (35%), Positives = 97/192 (50%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIH P K DG L W AME + + G K+IGVSN Sbjct: 111 LNYVDLYLIHSPFFAKSDGEL----------------QQAWAAMEKVQQAGKAKAIGVSN 154 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 ++ LE L+ A + PV+NQ+E HPYL Q+ L F + +KI +Y PL R P Sbjct: 155 YHQSHLEATLKTAVIAPVINQIEHHPYLQQEELLRFQREKDIKIASYGPLTPILR---AP 211 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 P DPK+ +A + T +VL+R+ ID G++ + S SR+ VL F+L+ Sbjct: 212 GGP---VDPKVSELAAKYKVTEGEVLLRWSIDRGDVAVTTSSKESRLQEFLQVLTFQLTP 268 Query: 156 EDVALIDSFDCG 121 E+V I G Sbjct: 269 EEVREISQLGQG 280 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 110 bits (264), Expect = 4e-23 Identities = 64/203 (31%), Positives = 101/203 (49%), Gaps = 15/203 (7%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSL---------------FPTDQSGKIQFSDVDYVDTWKAME 562 + D Y +HWP+A GSL FP + G I+ V W+ +E Sbjct: 467 IDAFDCYALHWPEALAHRGSLTRLAEKSVARQEALTFPKNDRGDIETDSVSLQRAWENLE 526 Query: 561 PLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKIT 382 L + G +++G+ N + QLE +++ TV+P + QVE HPY Q L E+C RG+++ Sbjct: 527 ALHERGWTRTLGLCNVSQTQLETVIETGTVRPALVQVERHPYQPQTDLIEYCHERGIRVV 586 Query: 381 AYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRS 202 A+SPL +P L+++P L AIA+ G + A V++ + + G + IP S T S Sbjct: 587 AHSPLSAPG----------LLDEPVLAAIAEEYGLSPAGVVLAWNVTQGVVPIPSSTTPS 636 Query: 201 RIASNFDVLDFKLSREDVALIDS 133 I N +L E A I++ Sbjct: 637 HIVENLAAAGQRLDAEACARIEA 659 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 109 bits (263), Expect = 5e-23 Identities = 56/157 (35%), Positives = 95/157 (60%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 DY TW+A+E L +EG +++IGVS+F +++L L+ VKP VNQ+E + + + + ++ Sbjct: 113 DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQ 172 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 + E GV+ A++P + +P L+ IA++ KT AQV++R+ + Sbjct: 173 YMEKEGVQPEAWAPFAEGAN--------HIFTNPLLEEIAEKHHKTTAQVMLRWFLQRNY 224 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 +VIPKSV + R+A N+DV DF+L +D+ I + D G Sbjct: 225 VVIPKSVHKKRLAENYDVFDFELDADDMKKIKTLDQG 261 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 109 bits (263), Expect = 5e-23 Identities = 62/190 (32%), Positives = 103/190 (54%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V+YL+L+LIHWP K YV+TW+A L GL++SIGVSN Sbjct: 99 VEYLELFLIHWPIPAKNL------------------YVETWEASIELEASGLIRSIGVSN 140 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + +ERL++ V P VNQ+E HP+ Q ++++ G+ I +YSP GS Sbjct: 141 FTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFGS-------- 192 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + ++ + + +A R + AQ+++R+ + G +P++ +R + N DV DF+LS Sbjct: 193 NGAAVLRNAVVMVLARRHDHSPAQIVLRWHLQQGLTPLPRTTNGARFSENVDVWDFELSE 252 Query: 156 EDVALIDSFD 127 E++ L+ S + Sbjct: 253 EEMKLLASLN 262 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 109 bits (263), Expect = 5e-23 Identities = 69/189 (36%), Positives = 95/189 (50%) Frame = -3 Query: 687 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 508 +DLYL+HWP ++ YV W+ M L GL +SIGVSN Sbjct: 102 VDLYLVHWPTPAADN------------------YVHAWEKMIELRAAGLTRSIGVSNHLV 143 Query: 507 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDP 328 LER++ V P VNQ+E HP Q+ + ++ A VKI ++ PLG K D Sbjct: 144 PHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPLGQ-----GKYD-- 196 Query: 327 QLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDV 148 L + A A GKT AQ ++R+ + G +V PKSV R R+ N DV DF L+ ++ Sbjct: 197 -LFGAEPVTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEI 255 Query: 147 ALIDSFDCG 121 A ID+ D G Sbjct: 256 AAIDAMDPG 264 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 109 bits (262), Expect = 6e-23 Identities = 64/194 (32%), Positives = 101/194 (52%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DLYL+H+ S PTDQ + + W E LV++GL+++IG+SNFN Sbjct: 106 YIDLYLLHY-------ASSPPTDQ---FELTHKPVFQVWAEFEELVQKGLIRNIGISNFN 155 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 + L L + +KPVVNQ+E + Y Q RL EFC+ + +TAY PL + D Sbjct: 156 VQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFCKKLNLHVTAYCPLAR-----CQNTD 210 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 D L ++ + K+V Q+++++ + G VIPK+ R+ N + DF L D Sbjct: 211 ----NDALLTELSTKYKKSVCQIMLQFLLSLGVSVIPKTQNLERLRENIESTDFSLDEAD 266 Query: 150 VALIDSFDCGGRLV 109 +A + + RL+ Sbjct: 267 IAKLKGLNKNFRLI 280 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 109 bits (262), Expect = 6e-23 Identities = 64/192 (33%), Positives = 95/192 (49%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V YLDLYL+HWP S+ P S +++ ++TW+A+E L EGL ++IGVSN Sbjct: 109 VDYLDLYLMHWPD------SMVPGRSSQEVR------LETWRALEELYDEGLCRAIGVSN 156 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L L + P VNQVE HP+ +L E C + Y PL Sbjct: 157 FLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHCRKENIVFEGYCPLAK-------- 208 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 Q + P + +A + G++ +Q+ IR+ I +G + IPKS RI N V F+L Sbjct: 209 --GQALTHPHILELAKKYGRSASQICIRWSIQNGVVTIPKSTKPDRIYENCQVFGFRLED 266 Query: 156 EDVALIDSFDCG 121 ++A + + G Sbjct: 267 SEMAALSTLHDG 278 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 109 bits (262), Expect = 6e-23 Identities = 62/183 (33%), Positives = 98/183 (53%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V+YLDL LIHWP GS ++ + V++W M ++ EG ++S+GVSN Sbjct: 101 VEYLDLLLIHWP------GSSLKSENPANKKLR----VESWNVMCEMMAEGKLRSVGVSN 150 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F LE L + + V P VNQVE HP+ +Q L ++C + AYS LGSP + K Sbjct: 151 FEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYCNENNIHFQAYSSLGSP--TYRK- 207 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 QL E+P +K +A + + +L+ + G V+P++ +A+NF V +++ Sbjct: 208 ---QLSEEPLIKELAQKYNVEIPVLLLGFAYCQGISVLPRTTNPEHVATNFKVTKLAITQ 264 Query: 156 EDV 148 ED+ Sbjct: 265 EDI 267 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 109 bits (261), Expect = 9e-23 Identities = 65/189 (34%), Positives = 102/189 (53%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIHWP + + + ++ DTW+AME ++IGVSN Sbjct: 105 LDYVDLYLIHWPNP-----------AAMRDNWEQLN-ADTWRAMEEAYTARKARAIGVSN 152 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F K L+ LL+ A V P VNQ+ +P + + + + AYSPLG+ Sbjct: 153 FRPKHLDALLKTAKVVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAYSPLGTG------- 205 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++ P+LK +AD+ K+VAQV++R+ + G + +PKSV RI N ++ DF+LS Sbjct: 206 ---KIFSIPELKTLADKYDKSVAQVVLRWSLQHGFLPLPKSVHADRIEQNTELFDFELSD 262 Query: 156 EDVALIDSF 130 +D+ +ID F Sbjct: 263 DDMKVIDGF 271 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 109 bits (261), Expect = 9e-23 Identities = 65/198 (32%), Positives = 96/198 (48%), Gaps = 7/198 (3%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 523 ++YLD++L+HWP A K D +D G TW+AME V + + IGV Sbjct: 93 LEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAMEACVDKKQTRFIGV 152 Query: 522 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 SN + L LL + +KP NQ E PY RL EFC + G+ +TAY PLG R A Sbjct: 153 SNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYVTAYRPLGGRCRVDA 212 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLI-----RYQIDSGNIVIPKSVTRSRIASNFDV 178 K + DP L+ +A + TV+++++ R+ VIPKS R R N + Sbjct: 213 KAP----LTDPALEELAKKANLTVSELILAWHWTRWGTSGTYSVIPKSSDRERQKQNLES 268 Query: 177 LDFKLSREDVALIDSFDC 124 + +L+ + + C Sbjct: 269 VKLRLTPDQMDAFARLGC 286 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 108 bits (260), Expect = 1e-22 Identities = 66/192 (34%), Positives = 106/192 (55%) Frame = -3 Query: 687 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 508 +DLYL+HWP K+D + +TW+A+E L EGLV++IGVSNF + Sbjct: 106 VDLYLVHWP---KQD-----------------TFFETWRAVEKLYDEGLVRAIGVSNFEA 145 Query: 507 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDP 328 L+RL A V PVV+Q+E HP+ + L + E + A+SPLG Sbjct: 146 HHLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAWSPLGRGG--------- 196 Query: 327 QLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDV 148 ++++ L +A + GK+ AQ+++R+ + + +IPKS T SRI N D+ DF+L+ D+ Sbjct: 197 -VLQEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRIRENADIYDFELTEADM 255 Query: 147 ALIDSFDCGGRL 112 ++ + G R+ Sbjct: 256 RQVERLNNGERV 267 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 108 bits (260), Expect = 1e-22 Identities = 62/188 (32%), Positives = 103/188 (54%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 N+ Y DLYLIHWP + D+ YV+ W+A+ + G ++SIGV Sbjct: 100 NLDYYDLYLIHWPNPIQ-----------------DI-YVEAWQALIEAKRRGYIRSIGVC 141 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NF + LERL Q P +NQ+E HP+ NQ+ +++ + + ++SPL A+ Sbjct: 142 NFLPEHLERLKQETGELPTINQIELHPFFNQEDQRKWHQEHQIATESWSPL-------AR 194 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 +D +++ P L+ +A +TV+Q+++R+ I IPKS T SR N + DF+LS Sbjct: 195 TND--VLDHPVLQKLASNHNRTVSQIILRWHYQLDAIAIPKSATPSRQLENISIFDFELS 252 Query: 159 REDVALID 136 E++++I+ Sbjct: 253 DEEMSIIN 260 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 108 bits (260), Expect = 1e-22 Identities = 62/177 (35%), Positives = 95/177 (53%), Gaps = 6/177 (3%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEGLV 538 ++ Y+DL L+HWP + D +++ + G +++SD D++ T+K +E G Sbjct: 99 SLDYVDLLLVHWPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRT 158 Query: 537 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 358 KSIGVSN + L+RLL P VNQ E HPYL QK+ EF E G+ +TA+SPLGS Sbjct: 159 KSIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLGS- 217 Query: 357 DRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 187 +L E+P IA + + VLI + + V+PK+ + R+ +N Sbjct: 218 -----STGALKLHENPIAVEIAQKHNTSTGSVLINWHVSQKRAVLPKTRSIERVVAN 269 >UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans Length = 321 Score = 108 bits (260), Expect = 1e-22 Identities = 66/194 (34%), Positives = 101/194 (52%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLD+Y+IH PQ D + + K TW+ ME L ++ V+SIGVSN++ Sbjct: 99 YLDMYMIHMPQL--PDWIVNQKETKEK----------TWRQMELLYEDEHVRSIGVSNYS 146 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 + L+ LL+ A++ P NQVE HP+ +Q LK +C+ G+ Y PL Sbjct: 147 IEDLDELLEFASILPHANQVELHPWFHQADLKNYCDELGILTMGYCPLAK---------- 196 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 + +ED L IA + K+ AQ+ +R+ I +PKS R+ N +V DF+LS ED Sbjct: 197 GKYLEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKSTDCRRLKENTNVFDFELSAED 256 Query: 150 VALIDSFDCGGRLV 109 + ++SF R + Sbjct: 257 MNTLNSFSSQNRKI 270 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 107 bits (257), Expect = 3e-22 Identities = 68/192 (35%), Positives = 101/192 (52%), Gaps = 2/192 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + YLD YLIHWP DGS D IQ + TW+A+E L ++ V+SIGVSN Sbjct: 120 LDYLDCYLIHWPGVKGLDGS----DSGNSIQRAQ-----TWRALEKLYQDKKVRSIGVSN 170 Query: 516 FNSKQLERLLQ--HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWA 343 + L LL + +KP +NQVE HP QK L EFC+ + + +Y L Sbjct: 171 YTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLLEFCKNNKIILESYGSLAGG----- 225 Query: 342 KPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 +L+ + +K A ++G+T +Q+L+RY ++ VIPK+ R+ N +LDF L Sbjct: 226 -----RLLNNESVKEFAKKVGRTPSQLLLRYCLEHNCPVIPKTENVHRLIENQMILDFTL 280 Query: 162 SREDVALIDSFD 127 S + V +D + Sbjct: 281 SDDIVNSLDKLN 292 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 107 bits (256), Expect = 3e-22 Identities = 64/194 (32%), Positives = 111/194 (57%), Gaps = 1/194 (0%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYL+H P +P Q G++ D +D W+AME + + G K+IGVSN Sbjct: 102 LDYVDLYLVHAP---------WPWGQVGRVY--DEANLDVWQAMEAIYQSGRAKAIGVSN 150 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + L+ +L AT+ P+VNQ++ + + ++ +F E + + AYSPL + Sbjct: 151 FAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLVEAYSPLATGG------ 204 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 ++++P+++A AD+ G +VAQ+ +R+ + +G + +PK+V + I +N LDF +S Sbjct: 205 ----VLDNPQVQAYADKYGVSVAQLALRFVLQNGVLPLPKAVNPAHIEANTQ-LDFAISV 259 Query: 156 EDV-ALIDSFDCGG 118 D+ AL D D G Sbjct: 260 ADMQALNDLPDAAG 273 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 107 bits (256), Expect = 3e-22 Identities = 64/184 (34%), Positives = 100/184 (54%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DL LIH PQ + E G ++ W+AME VK G V+SIGVSN Sbjct: 100 LEYIDLLLIHSPQPWIEVNRTNDRHFKGNLE--------NWRAMEEAVKAGKVRSIGVSN 151 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + +E ++ + T+ P VNQ+E H L ++C+ G+KI AYSPL Sbjct: 152 FLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDYCKKLGIKIEAYSPL---------- 201 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +L+ D ++ A A + T AQ+++ + + G IVIPKS + + N ++ +FK+S Sbjct: 202 SHGKLLNDDQIIAYAKKYNVTPAQLMLAFDMQLGCIVIPKSDNVTEMKENLNI-NFKISD 260 Query: 156 EDVA 145 ED+A Sbjct: 261 EDIA 264 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 107 bits (256), Expect = 3e-22 Identities = 61/184 (33%), Positives = 100/184 (54%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL LIHWP G I+ +TW+ +E V +G ++SIGVSNFN Sbjct: 126 YIDLVLIHWPV-------------KGHIK-------ETWQILEEYVDKGKIRSIGVSNFN 165 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 L+ LL++A ++PVVNQ+E PY+ Q + + +G+++ A+ PLG Sbjct: 166 PHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTFRKGIQVEAWGPLGQ--------GV 217 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 +++DP + IA R GK+ AQV++R+ + G + IP+ + N + DF+LS + Sbjct: 218 TGVLDDPAIGEIAARHGKSAAQVILRWHMQRGLVTIPRCDNDAYTDENIRIFDFELSPSE 277 Query: 150 VALI 139 + +I Sbjct: 278 MEII 281 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 107 bits (256), Expect = 3e-22 Identities = 72/194 (37%), Positives = 107/194 (55%), Gaps = 18/194 (9%) Frame = -3 Query: 690 YLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 Y+DLYL+H+P YK D L P ++Q ++DY+DTW+AME LVK G+V+SIG+SN Sbjct: 122 YIDLYLMHFPVGYKYVCDEILMPMS-GDELQTVEIDYLDTWRAMENLVKLGMVRSIGLSN 180 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARG----VKITAYSPLGSPDRP 349 FN +Q++R++Q ++ KPVVNQVE P QK L ++C G T++S P Sbjct: 181 FNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNGNYCDSLFTSWSTKQKKSLP 240 Query: 348 ----WAKPDDPQLME----DPKLKAIADRLGKTV---AQVLIR-YQIDSGNIVIPKSVTR 205 + + + L KL AI + ++ + IR +ID G + IPK+ Sbjct: 241 SVFLFGRCETDWLRSTSALQVKLVAIFGSIFISIRLNLNINIRILEIDYGVVPIPKAANP 300 Query: 204 SRIASNFDVLDFKL 163 I N ++ DFKL Sbjct: 301 IHIKENLNIFDFKL 314 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 106 bits (254), Expect = 6e-22 Identities = 65/191 (34%), Positives = 105/191 (54%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 N+ YLDLYLIH P ++DV W+AME + G +K+IGVS Sbjct: 101 NLDYLDLYLIHQP-------------------YNDV--FGAWRAMESAYRSGQLKAIGVS 139 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NF+ QL L + + +KP++NQ+E +P+ K+ + GV++ A++P K Sbjct: 140 NFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDITYFSQYGVQVEAWAPFAE-----GK 194 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 D L + L+ IAD+ K++AQ+++R+ IV+ KSV R+A N D+ DFKL+ Sbjct: 195 ND---LFSNILLRKIADKHHKSIAQIVLRWLTQRNIIVVAKSVKPERMAQNLDIFDFKLT 251 Query: 159 REDVALIDSFD 127 +++A I++ D Sbjct: 252 HQELAEIETLD 262 >UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis Length = 273 Score = 105 bits (253), Expect = 8e-22 Identities = 66/190 (34%), Positives = 97/190 (51%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V L+LYLIHWP Q K Y +TW+ + + G SIGVSN Sbjct: 97 VTSLNLYLIHWP------------GQDRK------RYEETWQTLIQIRAIGKASSIGVSN 138 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L+ ++ + V P VNQ+E HPY QK L+ + RG+ T++SPLG Sbjct: 139 FTIDHLDHIIADSGVVPAVNQIELHPYFQQKELRAYHAERGIVTTSWSPLGR-------- 190 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + DP ++ IA + GKT AQV++ + + G VIPK+ +++R+ N + F L Sbjct: 191 --GAALNDPVIREIALKHGKTPAQVVLNWHLSLGLTVIPKASSKARLQENLEADSFALDE 248 Query: 156 EDVALIDSFD 127 ED+ I+S D Sbjct: 249 EDMQRIESLD 258 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 105 bits (253), Expect = 8e-22 Identities = 64/190 (33%), Positives = 95/190 (50%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL L+HWP PT G + W A+E G ++IG+SN+ Sbjct: 114 YVDLLLVHWP---------LPTLYGGDVALP-------WPALEDAFNAGGARAIGLSNYE 157 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 + +E + + ATV P V QVE HP+ L+ + + G+ A+SPL Sbjct: 158 REHVEAVREVATVAPHVLQVESHPFFPNADLRAYAQGLGMVFEAWSPLARG--------- 208 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 + + DP L I LG QV +R+ +D G++V PK+++R R+A+NFDV F L E Sbjct: 209 -RAVTDPTLVEIGAELGVGPTQVTLRWALDRGHVVFPKTLSRERMAANFDVFSFSLDPEQ 267 Query: 150 VALIDSFDCG 121 A ID+ D G Sbjct: 268 TARIDALDAG 277 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 105 bits (253), Expect = 8e-22 Identities = 64/186 (34%), Positives = 98/186 (52%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLDLYLIHWP+ E D+ +TW+A+E L + GLV++IGVSNF Sbjct: 102 YLDLYLIHWPRPDLELEDWAKLDR------------ETWRALERLYESGLVRAIGVSNFL 149 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 LE +L A V P+V+Q+E HP Q FC+ + + A+SPLG Sbjct: 150 PHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQNHSILVEAWSPLGR---------- 199 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 +L + L +A G + AQ+ +R+ + G + +PKS + R+A N D+ F L+ E+ Sbjct: 200 NRLTGNGVLTRLAAEHGVSPAQICLRFALQRGVLPLPKSSSPERMAENLDLFSFSLTGEE 259 Query: 150 VALIDS 133 +A + + Sbjct: 260 MAALST 265 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 105 bits (253), Expect = 8e-22 Identities = 62/200 (31%), Positives = 103/200 (51%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+D+YL+H+P+ D D ++ + Y + +E G V+SIGVSN+ Sbjct: 113 YIDMYLVHYPKPNDSDN-----DDVNNAEYRKIAY----EVLEEAKAAGKVRSIGVSNYE 163 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 LE L +A V P NQ+E HP+ + L+++C+ + + A+S L + Sbjct: 164 IVHLEELKTYAKVPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFSSLAR--------HE 215 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 P+L+EDP + +A + +V VL+ + + ++PKSVT SRI NF V+D L+ ED Sbjct: 216 PKLIEDPVVVELAKKHNTSVPLVLLAWALRQNVGIVPKSVTPSRIVENFKVIDIALTPED 275 Query: 150 VALIDSFDCGGRLVPMTASL 91 + + + D G + T L Sbjct: 276 IQSLTALDRGQHYIRCTGWL 295 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 105 bits (253), Expect = 8e-22 Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 15/203 (7%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSL---------------FPTDQSGKIQFSDVDYVDTWKAME 562 + D Y +HWP A + G L FP + G+ +DV W+ +E Sbjct: 465 IDAFDCYALHWPSALEHRGELNRLAEKPVERQETLTFPEGEDGEPATADVALATAWRNLE 524 Query: 561 PLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKIT 382 + + G +++G+ N + QLE +L+ + P + QVE HPY + L E C RG+++ Sbjct: 525 AVHERGWARTLGICNVSRAQLETVLETGEIDPALVQVERHPYRPRNGLVELCHGRGIRVV 584 Query: 381 AYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRS 202 A+SPL +P L+++P L AI G + A+V+I + G + IP S S Sbjct: 585 AHSPLSAPG----------LLDEPVLNAIGTERGLSPAEVVIAWNASQGVVPIPSSTAES 634 Query: 201 RIASNFDVLDFKLSREDVALIDS 133 + SN +L+ ++VA ID+ Sbjct: 635 HVVSNLAAGSERLTADEVARIDA 657 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 105 bits (252), Expect = 1e-21 Identities = 66/197 (33%), Positives = 102/197 (51%), Gaps = 1/197 (0%) Frame = -3 Query: 693 QYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF 514 +++D+ LIHWP K+ +VDTWKA+ L G KSIGVSNF Sbjct: 97 EHVDMLLIHWPCPEKDQ------------------FVDTWKALIELRDAGKAKSIGVSNF 138 Query: 513 NSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPD 334 + L+R++ V P +NQ+E HP Q+ +++ E G+ ++SPLG Sbjct: 139 REEDLKRIIDETGVTPALNQIELHPSFQQRDMRKVHEDLGIVTQSWSPLG---------- 188 Query: 333 DPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRE 154 + M + ++AIA+ G+ V++R+ I G IPK+ +R I +NF L F+LS E Sbjct: 189 QGKGMSNEVIEAIAEETGQPETAVILRWHIQHGLCPIPKASSRDHIEANFKALSFELSDE 248 Query: 153 DVALIDSF-DCGGRLVP 106 + ID+ D GR+ P Sbjct: 249 QMGRIDALDDPKGRMGP 265 >UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 293 Score = 105 bits (252), Expect = 1e-21 Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 1/158 (0%) Frame = -3 Query: 585 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEF 409 +D+W + LV+EG V+S+GVSNF ++ L+ V PV NQ+ECHP+ QK ++ Sbjct: 133 LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAA 192 Query: 408 CEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI 229 EA + + AY PL DP LK +A GKT AQV++R+ + G + Sbjct: 193 SEAHSIIVQAYCPLARG----------HYYGDPTLKKVAAETGKTEAQVMLRWLVQHGIV 242 Query: 228 VIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGR 115 +PKS R N + L F LS E + +D+ D G + Sbjct: 243 ALPKSSNLQRQVENAECLTFVLSDEQMKELDALDRGDK 280 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 105 bits (251), Expect = 1e-21 Identities = 65/200 (32%), Positives = 101/200 (50%), Gaps = 4/200 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVD-YVDTWKAMEPLVKEGLVKSIGVS 520 + +LD +HWP + + + D D Y+ W A+E LV GLV+ +G S Sbjct: 115 LDHLDAVFVHWPFPNHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTS 174 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPW-- 346 N +L+ LL+ A + P +N++E HP Q L C G++ YSPLGSP RP Sbjct: 175 NTTVAKLDLLLRDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGSPSRPERD 234 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF-DVLDF 169 P D EDP + IA G A V +++ + G + IP SV ++ +N V++ Sbjct: 235 RTPGDVVDTEDPVVVRIAREHGVHPALVCLKWAVARGQVPIPFSVKPAQYTANLRAVVED 294 Query: 168 KLSREDVALIDSFDCGGRLV 109 L+ ++VA + + D G RL+ Sbjct: 295 PLTAQEVADLAAADRGERLI 314 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 104 bits (249), Expect = 2e-21 Identities = 63/190 (33%), Positives = 97/190 (51%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+D+Y+IHWP + D DTWKA L EG+ +++GV N Sbjct: 111 LDYVDMYMIHWPTPF------------------DWRSTDTWKAFVKLRDEGMARTLGVCN 152 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L+RL + P VNQ+E HP Q+ + FC+ G+ + AYSP+ A+ Sbjct: 153 FMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPM-------ARG 205 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 D D ++ IA + AQV++R+ I++G I+IPKSV R N ++ F L+ Sbjct: 206 ADLN-AGDGTIEKIAAAHEVSPAQVILRWHIENGTIIIPKSVHADRQKENLNLFGFALTA 264 Query: 156 EDVALIDSFD 127 ++ A ID+ D Sbjct: 265 DEHAAIDALD 274 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 103 bits (248), Expect = 3e-21 Identities = 55/157 (35%), Positives = 89/157 (56%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 D W+AME K G +KSIGVSN ++ + P VNQVE +PY Q+ L++ Sbjct: 115 DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVEFNPYFQQQPLRQ 174 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 A+ VK+ A++PLG ++ L ++P ++ +A + K Q+++R++ G Sbjct: 175 LLAAQDVKLEAWAPLGQGNQ--------ALFKEPIIQQLAIKYHKDAGQIILRFEHQEGV 226 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 IV PKSV +RI SN D+ DF+L+ ++A + + D G Sbjct: 227 IVFPKSVHSARIKSNRDIFDFELTSTEMAQLRALDTG 263 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 103 bits (247), Expect = 4e-21 Identities = 65/194 (33%), Positives = 94/194 (48%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V+++DLYLIHWP S Y + WKAME L +++IGVSN Sbjct: 103 VEFVDLYLIHWPVP------------------SQGLYTEAWKAMEKLYANSQIRAIGVSN 144 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + L+ LL A V P VNQVE HP Q+ L C G+ + AYSPLG Sbjct: 145 FLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYSPLGQGAD----- 199 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + +K +A + T AQ+++ + + G IVIPKS R+ N + +LS Sbjct: 200 -----LNATAVKDLAGKYDATPAQIVLAWHLAQGTIVIPKSADSKRMRENLGAVAVELSP 254 Query: 156 EDVALIDSFDCGGR 115 +++ I + + G R Sbjct: 255 AELSEISALESGAR 268 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 103 bits (247), Expect = 4e-21 Identities = 61/192 (31%), Positives = 94/192 (48%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DL LIHWP +++ ++ TWK E L +G V+SIGVSN Sbjct: 100 LDYVDLLLIHWPLPRRDE------------------FISTWKTFERLQADGKVRSIGVSN 141 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F LERL+ V P VNQ++ P + + + G+ +YSPLG+ Sbjct: 142 FKPAHLERLMAACDVVPAVNQIQVSPAITRIVDIAYNRRHGIVTESYSPLGA-------- 193 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 L+ P L IA + GKT Q+++R+ ++ G + IPK+ R+ N D+ F L Sbjct: 194 -GSDLLNAPVLGRIAQKHGKTPGQIVLRWHVEQGLVAIPKTANPQRMKENLDIFGFTLDA 252 Query: 156 EDVALIDSFDCG 121 +D + I + D G Sbjct: 253 DDTSAIATLDGG 264 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 103 bits (247), Expect = 4e-21 Identities = 68/201 (33%), Positives = 103/201 (51%), Gaps = 12/201 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKE------DGSLFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLV 538 + YLDLYLIHWP + D +P + G + V +DTW AM LV GLV Sbjct: 119 LDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLV 178 Query: 537 KSIGVSNFNSKQLERLLQH-ATVK----PVVNQVECHPYLNQKRLKEFCEARGVKITAYS 373 KSIG++N + + L++ A K PV+NQVE HP + L + + + AY Sbjct: 179 KSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHPGIVDGDLIGCLGSHDMLMAAYC 238 Query: 372 PLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIA 193 PLG P P L++DP L++++ G + A++L+ + +D N+VI KS +R I Sbjct: 239 PLGMPTCS-TPPGFQSLLDDPVLRSLSAFSGFSPARLLLNWSVDRHNVVIVKSASREHIR 297 Query: 192 SNFDVLDFKLSREDVALIDSF 130 SN F L ++D++ Sbjct: 298 SNAKAARFALDDRTRLVLDNY 318 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 102 bits (245), Expect = 7e-21 Identities = 61/189 (32%), Positives = 101/189 (53%) Frame = -3 Query: 693 QYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF 514 +YLDL L+H+P+ P D + + + DTW A+E L EG ++SIGVSN+ Sbjct: 102 KYLDLVLVHYPR---------PLDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNY 152 Query: 513 NSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPD 334 +E + + T++P VNQ+E HP+ +K L+ +C + A+SPLG ++ Sbjct: 153 EPHHIEEMRSYITIEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSPLGRGNK------ 206 Query: 333 DPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRE 154 L+ D ++ IA TVA V++ + + V+ KSVT SR+A N+ L +LS + Sbjct: 207 --TLLGDSTMERIALCHKTTVANVILAWIMKGKYGVVAKSVTPSRVAENYTSLSLELSDD 264 Query: 153 DVALIDSFD 127 + I+ + Sbjct: 265 EFEKINGLN 273 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 102 bits (244), Expect = 1e-20 Identities = 52/150 (34%), Positives = 87/150 (58%) Frame = -3 Query: 576 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEAR 397 ++AME K+G+++ IG+SNF +K ++ V P +NQ E H L QK L+E +++ Sbjct: 118 YRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHLLLQQKPLREAMKSK 177 Query: 396 GVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPK 217 + ++SP + ++E+P LK+IA + KT AQV++R+ I+ G VIPK Sbjct: 178 KTLLQSWSPFIA--------GKGSILENPTLKSIAQKYNKTPAQVVLRFLIEQGISVIPK 229 Query: 216 SVTRSRIASNFDVLDFKLSREDVALIDSFD 127 + R+R+ N +V DF LS +D ++ D Sbjct: 230 TSKRARMQENLNVFDFSLSAQDTQILKELD 259 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 102 bits (244), Expect = 1e-20 Identities = 57/154 (37%), Positives = 87/154 (56%), Gaps = 1/154 (0%) Frame = -3 Query: 585 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL-QHATVKPVVNQVECHPYLNQKRLKEF 409 + +WKAME V G ++S+GVSN+ K L+ L + P VNQ+E HP+L+Q + ++ Sbjct: 125 IASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKY 184 Query: 408 CEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI 229 C++ + I AYSPL R + D KL IA +L +VAQ+LIR+ + G I Sbjct: 185 CQSHDIAIEAYSPLTHGIR----------LNDEKLVPIAKKLNISVAQLLIRWSLQKGYI 234 Query: 228 VIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 I KS + + S+ DV +F + + V + SFD Sbjct: 235 PIIKSTKKEHMLSDLDVFNFTIPDDVVQELSSFD 268 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 101 bits (243), Expect = 1e-20 Identities = 53/155 (34%), Positives = 90/155 (58%), Gaps = 2/155 (1%) Frame = -3 Query: 585 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKE 412 ++TW+AM+ V EGLVKSIGVSN+ K ++ LL + KPVVNQ+E P++ ++ L + Sbjct: 125 LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELAD 184 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 +C+++G+ + A++PL + M +P L + + + QVLIR+ + G Sbjct: 185 YCKSKGLVVEAFAPLCHGYK----------MTNPDLLKVCKEVDRNPGQVLIRWSLQHGY 234 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 + +PK+ T R+ N +F+LS E + +D D Sbjct: 235 LPLPKTKTVKRLEGNLAAYNFELSDEQMKFLDHPD 269 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 101 bits (242), Expect = 2e-20 Identities = 53/113 (46%), Positives = 72/113 (63%), Gaps = 1/113 (0%) Frame = -3 Query: 513 NSKQLERL-LQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 +S L RL L A V P V QVECHP Q +L FC+++GV +T +SPLGSP W K Sbjct: 141 HSMILARLELLVARVPPAVIQVECHPSWQQSKLHAFCKSKGVHLTGFSPLGSPGTTWFKG 200 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDV 178 D +++ P L A++LGK+ AQV +R+ + G+ V+PKS + SRI NFDV Sbjct: 201 D---ILKHPVLTMAAEKLGKSPAQVALRWGLQMGHSVLPKSTSESRIKENFDV 250 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 100 bits (240), Expect = 3e-20 Identities = 50/105 (47%), Positives = 70/105 (66%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYLIHWP K+ GS+ ++ VD TWKAME L G ++IGVSN Sbjct: 105 LEYVDLYLIHWPARIKK-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSN 159 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKIT 382 F++K+L LL+ A V P VNQVECHP Q +L+EFC+++GV ++ Sbjct: 160 FSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLS 204 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 99 bits (238), Expect = 5e-20 Identities = 59/153 (38%), Positives = 85/153 (55%) Frame = -3 Query: 597 DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRL 418 +V +T KA+ + +G ++IG+SNF S QLE + + +QVE HPYL+ K L Sbjct: 114 EVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTL 173 Query: 417 KEFCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDS 238 K + GV ITA+SPL ++ +DP L I GKT QV +R+ I Sbjct: 174 KAKADQLGVSITAWSPLA----------QGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQ 223 Query: 237 GNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 139 G I IP++ RI NFD+LDF+LS +++A I Sbjct: 224 GIIAIPRTSNPKRIEENFDILDFELSEKEMAQI 256 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 99 bits (238), Expect = 5e-20 Identities = 58/157 (36%), Positives = 86/157 (54%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 D W AME L +G +K+IGVSNF ++ L + P VNQ+E +P+ Q + E Sbjct: 112 DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQQQSKNIE 171 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 GV + A++P K D + +P L IA++ GK+VAQV++R+ I+ Sbjct: 172 ALRKEGVAVEAWAPFAE-----GKND---IFTNPILTKIAEKYGKSVAQVILRWLIEQDI 223 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 IV+ KSV R+A N V DF+LS ED + I + + G Sbjct: 224 IVLAKSVKPERMAQNLAVFDFELSEEDKSAIATLNQG 260 >UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr8 scaffold_23, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 219 Score = 99 bits (238), Expect = 5e-20 Identities = 65/181 (35%), Positives = 95/181 (52%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + ++DLYLIHWP K+ + T IQ D TW+AME L G V++IGVSN Sbjct: 27 LDFIDLYLIHWPVRMKKSSVV--TKPENLIQ---PDIPSTWRAMEALYDSGKVRAIGVSN 81 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 ++K+L LL+ A V P GV +T YSPLGSP K Sbjct: 82 LSTKKLGDLLEIARVPPP----------------------GVHLTGYSPLGSPGTVTLKS 119 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 + +++ P L +A++LG++ AQV +R+ + G+ V+PKS SRI NFDV + + Sbjct: 120 E---VLKHPVLNIVAEKLGRSPAQVALRWGLQMGHSVLPKSTNESRIKENFDVFGWSIPE 176 Query: 156 E 154 + Sbjct: 177 D 177 >UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 253 Score = 99.5 bits (237), Expect = 7e-20 Identities = 54/152 (35%), Positives = 84/152 (55%) Frame = -3 Query: 582 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 403 + W+A+ ++GL + IGVSN++ + +E L+ PVVNQVE P+ + LK + + Sbjct: 100 ELWRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVEWSPFGHDLELKHYAD 159 Query: 402 ARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVI 223 G+ I AYSPL R ++D L A++ GKT AQVLIR+ ++ G + I Sbjct: 160 FNGIVIQAYSPLTRATR----------LDDAALCETAEKYGKTPAQVLIRWNLERGTVPI 209 Query: 222 PKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 PK+ S + N V DF L + D+ +DS + Sbjct: 210 PKANLHSHMKENISVFDFTLEKSDLESLDSLN 241 >UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 315 Score = 99.1 bits (236), Expect = 9e-20 Identities = 56/188 (29%), Positives = 101/188 (53%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 +V Y+D++L+HWP A DG D+ +V+T+K ME LV +S+GV Sbjct: 68 DVGYIDIFLLHWPNASGPDGRWRGIDERPT-------FVETYKKMEKLVGPKC-RSLGVC 119 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 + + K ++ LL+ TVKPV+NQ+E HP+ +L +C +G+++ ++ PLG + Sbjct: 120 SLSQKSMDVLLKECTVKPVINQIEVHPFNPSLKLVPYCLDKGIQVISWGPLGGGPKS-LY 178 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLS 160 D + L ++A R ++ ++I + + G + IP S +R+R+ N + L+ Sbjct: 179 FDTSSMYNHKTLTSLASRYNVSIELIMISWLVQRGIVPIPHSASRARMDDNLSPV--SLT 236 Query: 159 REDVALID 136 E+V I+ Sbjct: 237 DEEVGQIN 244 >UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 253 Score = 98.7 bits (235), Expect = 1e-19 Identities = 49/114 (42%), Positives = 70/114 (61%), Gaps = 7/114 (6%) Frame = -3 Query: 696 VQYLDLYLIHWPQA--YKEDGSLFP-----TDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 538 + Y DL+++H+P A Y + +P +D+ G +Q S +TW+AME LV EGL Sbjct: 79 IDYFDLFIVHFPVALRYVDPAVRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLA 138 Query: 537 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAY 376 KSIGVSNF L LL++A ++P Q+E HPYL Q L + E+ G+K+TAY Sbjct: 139 KSIGVSNFQGALLIDLLRYARIRPATLQIEHHPYLVQNTLLKLAESEGIKVTAY 192 Score = 38.7 bits (86), Expect = 0.14 Identities = 29/84 (34%), Positives = 40/84 (47%) Frame = -3 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 P L+++ LK +A+ G +V + G VIPKS +SR+ N V DF L +ED Sbjct: 171 PYLVQNTLLK-LAESEG---IKVTAYWATQRGLAVIPKSNNQSRLEQNLHVTDFDLEKED 226 Query: 150 VALIDSFDCGGRLVPMTASLGHKH 79 + I D R T LG H Sbjct: 227 LNAITKLDRNLRFNNPTDYLGTLH 250 >UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reductase; n=4; Saccharomycetales|Rep: NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 98.7 bits (235), Expect = 1e-19 Identities = 61/183 (33%), Positives = 96/183 (52%), Gaps = 2/183 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DLYL+H P KE L + WK ME L K G K+IGVSNF Sbjct: 115 YVDLYLLHSPFVSKEVNGL--------------SLEEAWKDMEQLYKSGKAKNIGVSNFA 160 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPLGSPDRPWAKP 337 + L+R+L+ A VKP VNQ+E P+L + + +FC+ + + AYSPLG + A+ Sbjct: 161 VEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQD 220 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 D E +K ++++ K+ AQ+++R+ G + + S RI+ ++ F L+ Sbjct: 221 DSQPFFE--YVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTA 278 Query: 156 EDV 148 E+V Sbjct: 279 EEV 281 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 98.7 bits (235), Expect = 1e-19 Identities = 55/156 (35%), Positives = 81/156 (51%) Frame = -3 Query: 588 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 409 ++DTW+ M + GLV+SIGVSNF L+ L+ V P VNQVE HPY Q L+ F Sbjct: 118 WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAF 177 Query: 408 CEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI 229 + G++ ++SPL +L+ + L+ +A G T QV++R+ + G+ Sbjct: 178 HDEHGIRTESWSPLARRS---------ELLTEQLLQELAVVYGVTPTQVVLRWHVQLGST 228 Query: 228 VIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 IPKS R N DV F L+ + V I + G Sbjct: 229 PIPKSADPDRQRENADVFGFALTADQVDAISGLERG 264 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 97.9 bits (233), Expect = 2e-19 Identities = 66/190 (34%), Positives = 96/190 (50%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYL+HWP P S +V + +M + + G SIGV N Sbjct: 106 MDYVDLYLLHWP---------CPQADS---------FVQAYDSMAEIQQSGGATSIGVCN 147 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F + L+ L Q A P VNQ+E HP +Q + RG+ A+SPLG Sbjct: 148 FYPEALDALKQ-AGHTPAVNQIEIHPGFSQAEQRSDNRDRGIVTEAWSPLGQG------- 199 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 Q + DP + IA G +VAQ +IR+ I G++VIP+S R+ NFDV F+LS Sbjct: 200 ---QNLTDPTIAKIAAEHGVSVAQAIIRWHIQRGDVVIPRSSKVERVRQNFDVFGFELSA 256 Query: 156 EDVALIDSFD 127 ++V+ I++ D Sbjct: 257 DEVSAIEALD 266 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 97.9 bits (233), Expect = 2e-19 Identities = 65/196 (33%), Positives = 99/196 (50%), Gaps = 2/196 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL L+HWP +V +T KAM + + G V+ IGVSNF Sbjct: 99 YVDLLLLHWP-------------------VPEVPIAETMKAMNEVKEAGQVRHIGVSNFT 139 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 L+ H+ V NQVE HPYL+Q + C A G+ +TAYSP+ Sbjct: 140 VDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAMTAYSPIA----------Q 189 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIV-IPKSVTRSRIASNFDVLDFKLSRE 154 ++ +D + IA + AQ+++R+ ID +++ IP+S + I SNF++ D KLS+E Sbjct: 190 GKVFDDEVITEIAKAHNVSPAQIVLRWLIDQDSVIAIPRSSSDKHIKSNFEIADLKLSQE 249 Query: 153 DVALIDSF-DCGGRLV 109 + I+S GRL+ Sbjct: 250 ETGRINSLRSPDGRLI 265 >UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 313 Score = 97.9 bits (233), Expect = 2e-19 Identities = 61/186 (32%), Positives = 100/186 (53%), Gaps = 3/186 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DLYLIH P F + G + V WK ME L KEG KSIGVSN Sbjct: 113 LDYVDLYLIHSP--------FFDPEFKGSLTLEKV-----WKDMETLYKEGKAKSIGVSN 159 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPLGSPDRPWA 343 F+ K +E +L+ A +KP VNQ+E + +L + + +C+ +++ AYSPLG + Sbjct: 160 FSVKNIEEILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSPLGPLQK--- 216 Query: 342 KPDDP-QLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 +P++ +L + +A + GKT +Q+L+ + + G + I S RI ++ F Sbjct: 217 RPENSNELPFYNYIDELASKYGKTDSQILLNWVYNRGILPITTSSKTQRIIDAQNIFSFN 276 Query: 165 LSREDV 148 L++++V Sbjct: 277 LTKDEV 282 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 97.5 bits (232), Expect = 3e-19 Identities = 64/179 (35%), Positives = 97/179 (54%), Gaps = 10/179 (5%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPT---DQSGKIQFSD-----VDYVDTWKAMEPLVKE-G 544 + Y+DL+L HWP D + P D+ GK+ + D + Y+D + ++E ++ Sbjct: 106 LDYVDLFLQHWPVVLHGDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTS 165 Query: 543 LVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 367 VKSIGVSN++ +L +LL KPVVNQ+E HP L Q+ L ++C GV I+AYSP+ Sbjct: 166 KVKSIGVSNYSIPKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPV 225 Query: 366 GSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIAS 190 GS P K QL+ + +A + +V ++ Y I G V+P+S RI S Sbjct: 226 GSNGAPVLK---LQLINE-----LASKYDVSVNEIANAYHILQGRSVLPRSSNLERIKS 276 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 97.1 bits (231), Expect = 4e-19 Identities = 57/155 (36%), Positives = 87/155 (56%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 D W+A+E K G KSIGVSNF QL L + VKPVVNQ+E +P+ ++ + Sbjct: 115 DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNPWFQREPEVK 174 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 + + V + A++ P+A+ D + +P L I + GK+ QV++R+ I G Sbjct: 175 WNQKDDVAVEAWA-------PFAEGKD-GIFTNPVLTEIGKKYGKSNGQVILRWLIQRGI 226 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 IVIPKSV +R N D+ DF+L+ +D+ I + D Sbjct: 227 IVIPKSVHDARQKENIDIFDFELNNDDMQKIAALD 261 >UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2; Ostreococcus|Rep: Aldo/keto reductase family proteins - Ostreococcus tauri Length = 336 Score = 97.1 bits (231), Expect = 4e-19 Identities = 61/170 (35%), Positives = 84/170 (49%) Frame = -3 Query: 684 DLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSK 505 DL L+HWP KE P + + D TW+A+E +K G ++IGVSN+ Sbjct: 152 DLVLVHWPGRDKES----PDSERHR----DARRW-TWRALENALKMGQCRAIGVSNYELS 202 Query: 504 QLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQ 325 L LLQ VKP VNQ+E H Q L+ FCE+ GV + YSPLG Sbjct: 203 HLRELLQFCDVKPAVNQIELHARFPQTELRAFCESVGVHVVGYSPLGV----------GA 252 Query: 324 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVL 175 L++D ++KA A +G A L+R+ + G V+ KS R NF + Sbjct: 253 LLDDDRVKAYAATIGLRPAPALVRWTLSMGASVVVKSSAAERTEENFTAI 302 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 97.1 bits (231), Expect = 4e-19 Identities = 51/146 (34%), Positives = 82/146 (56%) Frame = -3 Query: 585 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFC 406 + + A+ L +EGL++S+GVSNF LE L + P +NQ+E +P+ Q+ + ++C Sbjct: 122 IAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYC 181 Query: 405 EARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIV 226 G+ + Y+P+ K D P L+E +++R GKTVAQ++IR+ + I Sbjct: 182 NKHGITVEGYAPVFR----GCKFDHPVLVE------MSERYGKTVAQIMIRWSVQKQYIT 231 Query: 225 IPKSVTRSRIASNFDVLDFKLSREDV 148 IPKS RI N V DF +S +D+ Sbjct: 232 IPKSSNPERILENAQVFDFVISEKDM 257 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 95.9 bits (228), Expect = 8e-19 Identities = 60/196 (30%), Positives = 97/196 (49%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V Y+DL LIH P A P+D + V + W E + GL K +GVSN Sbjct: 106 VDYVDLLLIHVPLAA-------PSDDYQQWNHKPVHQI--WAEFEEIHSLGLAKGLGVSN 156 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 FN + + LL + +KP+VNQ+E H + QK L EF + + A+SP+ + Sbjct: 157 FNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLVEFLKKVNIYPVAFSPMAKYN------ 210 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +++++ L IA + +VAQV+I + +VIP++ R+ NFD + S Sbjct: 211 ---EVVKNETLNQIAQKQNASVAQVMIAFMYHQDVVVIPRTAKIERLQHNFDAQKLQFSE 267 Query: 156 EDVALIDSFDCGGRLV 109 ED+ + + + R+V Sbjct: 268 EDIQTLRNLNSNTRVV 283 >UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; Ostreococcus|Rep: Glycerol dehydrogenase, putative - Ostreococcus tauri Length = 425 Score = 95.5 bits (227), Expect = 1e-18 Identities = 61/192 (31%), Positives = 100/192 (52%), Gaps = 2/192 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++YLDL+ + WP +K + D G ++ +TW A+E V +G VK++GV+N Sbjct: 213 IEYLDLFSLEWPVVHKPGTT--EVDSEGSLE-------ETWAALEKCVADGRVKALGVAN 263 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F+ +ERL++ VKP VN+VE HP L Q++L C GV + A++ L + Sbjct: 264 FSVPAVERLMKCCKVKPAVNEVELHPLLAQRKLVGVCRRYGVTVLAHTSLAN-------- 315 Query: 336 DDPQLMEDPKL-KAIADRLGKTVAQVLI-RYQIDSGNIVIPKSVTRSRIASNFDVLDFKL 163 D QL+E KL +A AD K A+ L+ R+ I G ++ + + I F+L Sbjct: 316 GDEQLLEHAKLVQAEADERNKQSAKALLTRWSIQRGVPLVINASSAIAIDECLAARTFRL 375 Query: 162 SREDVALIDSFD 127 + + L+D + Sbjct: 376 TNKQKVLLDDIE 387 >UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1; Candida parapsilosis|Rep: Conjugated polyketone reductase C2 - Candida parapsilosis (Yeast) Length = 307 Score = 95.5 bits (227), Expect = 1e-18 Identities = 66/188 (35%), Positives = 99/188 (52%), Gaps = 5/188 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 V Y+DL+LIH P F T+Q+ W+A+ K G V+ IG+SN Sbjct: 116 VDYVDLFLIHSP--------FFTTEQTHGYTLEQA-----WEALVEAKKAGKVREIGISN 162 Query: 516 FNSKQLERLLQHATVK---PVVNQVECHPYL-NQ-KRLKEFCEARGVKITAYSPLGSPDR 352 LE+L + PVVNQ+E HP+L NQ K + FC+ G+ + A+SPL Sbjct: 163 AAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLA---- 218 Query: 351 PWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLD 172 P A+ + L E LK +A++ KT AQVL+RY + G + + S SR+ + ++ D Sbjct: 219 PLARVETNALAET--LKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFD 276 Query: 171 FKLSREDV 148 F+L+ E+V Sbjct: 277 FELTDEEV 284 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 94.7 bits (225), Expect = 2e-18 Identities = 61/190 (32%), Positives = 95/190 (50%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + Y+DL+LIHWP DQ YV+ ++ + L+ GLV++IG SN Sbjct: 103 LDYIDLFLIHWPNP----------DQG--------TYVEAFEGLTRLLDAGLVRAIGTSN 144 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F L L V P VNQ++ PY + + A+G+ ++SP+G Sbjct: 145 FLPHHLNDLFAAGFV-PHVNQIQLDPYHLRPDITAIHAAKGIVTESWSPIGRAG------ 197 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +++ DP + IA+ GKT AQ+++R+Q+ SG + PKS R A N DV F L+ Sbjct: 198 ---EMLADPAITRIAEAHGKTPAQIVLRWQVQSGFVPAPKSADPERQAQNLDVFGFALTE 254 Query: 156 EDVALIDSFD 127 D+A ++ D Sbjct: 255 SDMAALNGLD 264 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 94.7 bits (225), Expect = 2e-18 Identities = 62/185 (33%), Positives = 96/185 (51%), Gaps = 1/185 (0%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLDL LIHWP T + +T AM +V+EGLV+ IGVSNF+ Sbjct: 98 YLDLLLIHWPN----------TPWMASLS-------ETLGAMNDVVEEGLVRHIGVSNFS 140 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 L+R ++ +QV+ HPY +Q++L ++C V +TAYSPL Sbjct: 141 PSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCRIHDVLLTAYSPLARGG-------- 192 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQI-DSGNIVIPKSVTRSRIASNFDVLDFKLSRE 154 +++DP L I ++ GK+ AQV +R+ + G IPK+ +R + +N V DF+L+ Sbjct: 193 --VLDDPALVQIGNKYGKSPAQVALRWLVQQDGVAAIPKASSREHLEANLAVFDFELTDA 250 Query: 153 DVALI 139 ++ I Sbjct: 251 EMERI 255 >UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 301 Score = 93.9 bits (223), Expect = 3e-18 Identities = 59/191 (30%), Positives = 101/191 (52%), Gaps = 1/191 (0%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL LIH+P+ ++ G+ D +I S V W+ +E + G V+SIGVSN+ Sbjct: 113 YVDLLLIHYPRD-RDTGN----DDDYEINKSRRKIV--WQTLEKAKESGRVRSIGVSNYE 165 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 L + ++A ++PV+NQ E PYL + LK+FC+ + + +YS L W D Sbjct: 166 VYHLVEMFEYAKIRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYSSL-----CWG---D 217 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNF-DVLDFKLSRE 154 +++++ L + + +T +L + S +IPKS T SRI N + + KL+ + Sbjct: 218 KEILQEKPLVDLCQKYNQTPQAILYAFAHCSNTSMIPKSATPSRIHDNLHNTIKIKLTED 277 Query: 153 DVALIDSFDCG 121 ++ + S D G Sbjct: 278 ELKSLRSLDKG 288 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 93.1 bits (221), Expect = 6e-18 Identities = 60/183 (32%), Positives = 94/183 (51%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 + ++DL LIH PQ + F K + V+ + A+E K G V+SIGVSN Sbjct: 108 LDFIDLMLIHSPQPWNS----FRKGDYFK------ENVEVYNALEDAQKAGKVRSIGVSN 157 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 F K LE +L++ KP NQ+ CH L ++C+ + + AYSP+ Sbjct: 158 FLQKDLENILKNCKTKPAANQILCHIGNTPFTLLDYCKKQNILAEAYSPIA--------- 208 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 +L++DP++ +A + + AQ+ IRY ++ G + +PKS T IA N V DF S+ Sbjct: 209 -HGELLKDPRVIELAKKYNVSPAQICIRYTLELGLVSLPKSKTPKYIAENAQV-DFTFSK 266 Query: 156 EDV 148 D+ Sbjct: 267 ADL 269 >UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cerevisiae Probable oxidoreductase YJR096W; n=2; Yarrowia lipolytica|Rep: Similar to sp|P47137 Saccharomyces cerevisiae Probable oxidoreductase YJR096W - Yarrowia lipolytica (Candida lipolytica) Length = 287 Score = 93.1 bits (221), Expect = 6e-18 Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 1/151 (0%) Frame = -3 Query: 576 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEFCEA 400 WKA+ V +G ++++ VSN+ K L+ T KPV+NQ+E P+ + + ++C Sbjct: 134 WKALSEFVDDGKIRTLAVSNYGVKHLKEFWDADTKYKPVLNQIESSPWNVHQDIHDYCNE 193 Query: 399 RGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIP 220 + + YSPL + ++P ++++A + KT AQ+LIR+ ID G + IP Sbjct: 194 HDIVVEQYSPLIRGKK----------FDEPGVQSLAKKYNKTPAQILIRWGIDKGMLPIP 243 Query: 219 KSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 KS R SN DV DFKL+ ++V + D Sbjct: 244 KSDQPQRQKSNADVFDFKLTPDEVTALQDLD 274 >UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropicalis|Rep: LOC548351 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 248 Score = 90.2 bits (214), Expect = 4e-17 Identities = 50/142 (35%), Positives = 73/142 (51%) Frame = -3 Query: 546 GLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 367 G+ +SIGVSNF L++L + + P +NQVE HP+ + L ++C + Y PL Sbjct: 106 GICRSIGVSNFLIHHLDQLKEDCNMVPHLNQVEYHPFQRPQELVDYCRRNNIVFEGYCPL 165 Query: 366 GSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 187 Q + P ++ IA GKT AQV IR+ I +G + IPKS RI N Sbjct: 166 AKG----------QALNHPVIQKIAKNYGKTPAQVCIRWSIQNGIVTIPKSTKEERIQEN 215 Query: 186 FDVLDFKLSREDVALIDSFDCG 121 +V F L+ EDV +++ G Sbjct: 216 CEVFGFVLADEDVLALNALHDG 237 >UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative aldo-keto reductase/oxidase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 274 Score = 90.2 bits (214), Expect = 4e-17 Identities = 64/200 (32%), Positives = 97/200 (48%), Gaps = 4/200 (2%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFP-TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 V +DL L+HWP + + +P D G QF++V GL + IGVS Sbjct: 95 VDQVDLLLLHWPSPHNK----YPLADYLG--QFAEV------------FDSGLARQIGVS 136 Query: 519 NFNSKQLE---RLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP 349 NF ++ RLL T+ NQVECH Y+ + + ++C+ G+ +TAYSPL Sbjct: 137 NFTKAMIDESIRLLDSRTI--TTNQVECHVYMQNRPIIDYCQNLGIAVTAYSPLARG--- 191 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 ++ DP L+ I G T Q+ + + I G++VIP S R RI NF+ Sbjct: 192 -------AVVGDPVLEEIGKARGATSDQIALAFLIAKGHVVIPSSSKRGRIMQNFEARKI 244 Query: 168 KLSREDVALIDSFDCGGRLV 109 L+ ++ I+ + G RLV Sbjct: 245 TLTPAEIKRIEGLEKGMRLV 264 >UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pezizomycotina|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 295 Score = 90.2 bits (214), Expect = 4e-17 Identities = 55/152 (36%), Positives = 84/152 (55%), Gaps = 4/152 (2%) Frame = -3 Query: 576 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV----KPVVNQVECHPYLNQKRLKEF 409 W+A+ K G V+SIGVSN+ LE L ++ + V Q E HP+ ++ + + Sbjct: 138 WRALVEAQKAGHVRSIGVSNYGIHHLEELEEYINSGVGGEISVGQYEIHPWCAREDIVAW 197 Query: 408 CEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI 229 + R V I AYSPL R +++P L+ +A + KT AQ+LIR+ + G + Sbjct: 198 LKKRNVVIEAYSPLVQAQR----------LDEPVLQNLAKKHNKTGAQILIRWSLQKGYV 247 Query: 228 VIPKSVTRSRIASNFDVLDFKLSREDVALIDS 133 +PKSVT SRI N V DF+LS ED+ +++ Sbjct: 248 PLPKSVTDSRIVENTQVFDFELSGEDMESLNT 279 >UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 151 Score = 89.4 bits (212), Expect = 7e-17 Identities = 49/152 (32%), Positives = 83/152 (54%) Frame = -3 Query: 582 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 403 D+W+A+E LV +G ++SIGVSNF K L++L A V P Q P+ K +++C+ Sbjct: 1 DSWRALEELVSQGKIRSIGVSNFEVKDLKKLKDIAKVPPSAIQNFFTPFYQDKATRQYCK 60 Query: 402 ARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVI 223 +K YS LG +P + + +L+ I TV+QV++++ ++ +VI Sbjct: 61 ENNIKYMGYSTLGGMYVREGFDKNP-VQNNFELQRIGGVFDATVSQVVLKWALEQDVLVI 119 Query: 222 PKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 P+S T + I +NF + +L + +A DS D Sbjct: 120 PQSRTPNHIRTNFHLDHVQLDSKQMAYFDSLD 151 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 89.0 bits (211), Expect = 1e-16 Identities = 54/159 (33%), Positives = 89/159 (55%), Gaps = 4/159 (2%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFN-SKQLERLLQHATVK---PVVNQVECHPYLNQK 424 D +KA+ +G VKSIG+SNF +K +E + T+ P ++Q+E HPY +K Sbjct: 115 DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEK 174 Query: 423 RLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQI 244 ++ + GV+I A+ PLG + P+L+E IA + K+V QV++R+ + Sbjct: 175 VARQLHDKYGVQIEAWGPLGRTANKYDTFHQPELVE------IAAKHDKSVGQVVLRWIM 228 Query: 243 DSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD 127 S I + KSV SR+A N D+ +F+L +D+ I++ D Sbjct: 229 QSNIITVAKSVNPSRMAENIDIFNFELDDDDMKKIETLD 267 >UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina baltica OS145|Rep: Aldo/keto reductase - Idiomarina baltica OS145 Length = 263 Score = 89.0 bits (211), Expect = 1e-16 Identities = 59/194 (30%), Positives = 93/194 (47%), Gaps = 1/194 (0%) Frame = -3 Query: 687 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 508 +DL LIHWP P D+ V +T A++ ++GL+K +GVSNF Sbjct: 88 IDLALIHWPS---------PNDE--------VPVEETLDALQKAQQDGLIKHLGVSNFTI 130 Query: 507 KQLERLLQHATVKPVV-NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 L R H ++ NQ+E HP+ + + C+ GVK+TAY PL Sbjct: 131 DLLNRAAAHVGKDEILTNQIEVHPFFQNHAITDACKQMGVKVTAYLPLAKG--------- 181 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 +M++ ++ IA++ + AQV I +Q+ + I IP + + SNFD KL ++D Sbjct: 182 -AVMDNSVMQNIAEKHNVSPAQVAIAWQLANDYIAIPSTTKVDHLKSNFDAQSLKLDQDD 240 Query: 150 VALIDSFDCGGRLV 109 + I D RL+ Sbjct: 241 MKAIADIDKDDRLI 254 >UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid reductase - Picrophilus torridus Length = 283 Score = 88.2 bits (209), Expect = 2e-16 Identities = 59/193 (30%), Positives = 92/193 (47%), Gaps = 3/193 (1%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 NV+ +DLY +HWP + VD +T KAME LV G+++ IGVS Sbjct: 92 NVKTIDLYQLHWPNRH-------------------VDIKETMKAMEHLVDTGMIRYIGVS 132 Query: 519 NFNSKQLERLLQHATVKPVV-NQVECHPYLN--QKRLKEFCEARGVKITAYSPLGSPDRP 349 NFN +L+ + + +V NQVE +P + + + EFC + I AYSPL Sbjct: 133 NFNVNELKSAMSAMSKYEIVSNQVEYNPLVRYIEPEISEFCRKNSISIIAYSPL-----M 187 Query: 348 WAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDF 169 DP ++ IA++ TV QV++ + + IPKS + N ++ Sbjct: 188 HGHDIDPISKDESPFNIIANKRNATVRQVILAWILSKNFFAIPKSNVPEHVIENVKSMNI 247 Query: 168 KLSREDVALIDSF 130 LS E+ ++ID + Sbjct: 248 NLSSEETSMIDHY 260 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 87.4 bits (207), Expect = 3e-16 Identities = 69/212 (32%), Positives = 107/212 (50%), Gaps = 29/212 (13%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++YLDLYLIHWP + +G+ ++D+V T+K+M L K ++ +IGVSN Sbjct: 131 LEYLDLYLIHWPIGFSSNGA------------KNLDHVQTYKSMISLPKSRVL-NIGVSN 177 Query: 516 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG--------- 364 F+ QL+ ++ T+ P ++Q+E HPYL Q +A G+K+TAYSPLG Sbjct: 178 FSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIKMTAYSPLGNTNPTYHSS 236 Query: 363 -SPD----------------RPWAKPDDPQ---LMEDPKLKAIADRLGKTVAQVLIRYQI 244 SP RP + P+ L+++P L IA+ T AQV +++ + Sbjct: 237 TSPSLSSSSSFSWASWTSLFRPSSSSSKPKAPPLLQNPILIDIAEERNCTPAQVALKWNM 296 Query: 243 DSGNIVIPKSVTRSRIASNFDVLDFKLSREDV 148 G VIPKS I N + +L+ D+ Sbjct: 297 GRGISVIPKSSHEEWIKENLQAGECELTHADL 328 >UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismortui|Rep: Oxidoreductase - Haloarcula marismortui (Halobacterium marismortui) Length = 264 Score = 87.4 bits (207), Expect = 3e-16 Identities = 53/188 (28%), Positives = 98/188 (52%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLDLYL+HWP + + I+ +T AM L +G ++++GVSNF+ Sbjct: 84 YLDLYLVHWP------------NPATSIR-------ETMNAMATLHDQGKIRNVGVSNFS 124 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 + QL A V VNQ+E HP+ Q ++ EFC + A +PLG Sbjct: 125 AYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAPLGR---------- 174 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 ++ D ++ ++++ ++ AQ+++++ +++ +V+PKS + + NFD+ D++L D Sbjct: 175 TKVFADDIIQDLSEKYDRSPAQIVLKWAVENNVVVLPKSSSPEHVRQNFDLFDWELDATD 234 Query: 150 VALIDSFD 127 ID+ + Sbjct: 235 RERIDAIE 242 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 87.0 bits (206), Expect = 4e-16 Identities = 53/157 (33%), Positives = 78/157 (49%) Frame = -3 Query: 591 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 412 D W AME L G +++IGVSNF+ ++ L V P VNQ+E +P+ Q Sbjct: 112 DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANLA 171 Query: 411 FCEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGN 232 GV I A++P K D + +P L I + GK+ AQV++R+ ++ Sbjct: 172 ILRKEGVAIEAWAPFAE-----GKND---IFNNPVLTKIGAKYGKSAAQVILRWLVEQDI 223 Query: 231 IVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 IV+ KSV R+A N + DF+L+ D I D G Sbjct: 224 IVLAKSVKPERMAQNLAIFDFELTEADKEEIAGLDQG 260 >UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 287 Score = 86.2 bits (204), Expect = 7e-16 Identities = 52/156 (33%), Positives = 79/156 (50%) Frame = -3 Query: 588 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 409 YVD WK + L++EG VK+IGVSNF L+ ++ V P VNQ++ P L + + Sbjct: 127 YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQIQLSPDLARTEPRAV 186 Query: 408 CEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI 229 G+ A+SP+G L +P + IA RL K+ AQVL+R+ + + Sbjct: 187 HRLLGIVTEAWSPIGR---------SSGLRANPLIIEIAQRLDKSPAQVLLRWHVQQDIV 237 Query: 228 VIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 IP++ + N V DF L+ ++A I D G Sbjct: 238 PIPQASDPLWLKENLSVFDFSLTAGEMASIRKLDRG 273 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 85.8 bits (203), Expect = 9e-16 Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 1/190 (0%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 + Y+DL L+HWP V +T A+ L K+GL ++IGVS Sbjct: 102 DTDYVDLLLLHWPD-------------------DRVPLSETIPALCELQKQGLTRNIGVS 142 Query: 519 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAK 340 NFN + ++A V VVNQVE HP++ QK L+ F + + AYSPL D Sbjct: 143 NFNIANIIEAKRYADVPIVVNQVEFHPFIKQKTLQTFLNNHHILLEAYSPLARGD----- 197 Query: 339 PDDPQLMEDPKLKAIADRLGKTVAQVLIRYQI-DSGNIVIPKSVTRSRIASNFDVLDFKL 163 + ++ +K IAD+ G T AQV + + + D I IPK+ + N D + +L Sbjct: 198 -----VFDNKIIKDIADKHGITAAQVSLAWILSDKHRIAIPKTSNPEHLQGNLDAIKVEL 252 Query: 162 SREDVALIDS 133 S +++ I S Sbjct: 253 SADELEKIGS 262 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 85.8 bits (203), Expect = 9e-16 Identities = 64/214 (29%), Positives = 93/214 (43%), Gaps = 3/214 (1%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y DL+LIH P P D + D W +E L ++GL K+IGVSN + Sbjct: 108 YFDLFLIHVP----------PNDDI------NYDLAKAWGVLEQLYEKGLAKAIGVSNHS 151 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPLGSPDRPWAKP 337 +LE +++ A +KP VNQ+E HP L + + +FC+ + + YSPL S + KP Sbjct: 152 PAELETIIKVAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLASNELEGEKP 211 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSR 157 D + +A + VL+R+ G + I S R + DFKLS Sbjct: 212 LDAVVAN------VAKNHNVSPGSVLLRWATQKGIVPITTSANAGRQKEALAIFDFKLSD 265 Query: 156 EDVALIDSFDCGGRLVPMTASLGHKH-HPFENEE 58 +V I HKH +P E E Sbjct: 266 GEVEEISKVGAESPRYQRLPIPSHKHYYPAEEGE 299 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 85.4 bits (202), Expect = 1e-15 Identities = 61/194 (31%), Positives = 92/194 (47%), Gaps = 1/194 (0%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL LIHWP P DQ V + +A+ +GL ++IGVSNF Sbjct: 90 YVDLTLIHWPS---------PKDQ--------VPMREYLEALADAKAQGLTRAIGVSNFT 132 Query: 510 SKQLERLLQHATVKPVV-NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPD 334 + ++ + NQ+E HPYL + L F +G+ +T+Y L + Sbjct: 133 IALTRQAIEILGADAIATNQIEVHPYLQNRTLIAFLREQGIHVTSYMTLAVGE------- 185 Query: 333 DPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRE 154 +++DP ++AIA R T AQV + + + G VIP S R+ + SN LS + Sbjct: 186 ---VLKDPVIQAIARRHDATPAQVTLAWALQQGYSVIPSSTKRANLESNLKAQSLHLSEQ 242 Query: 153 DVALIDSFDCGGRL 112 D+A I + D G RL Sbjct: 243 DMAEIAALDRGERL 256 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 85.4 bits (202), Expect = 1e-15 Identities = 74/216 (34%), Positives = 96/216 (44%), Gaps = 21/216 (9%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS- 520 ++YLDLYLIH PQ K D WK +E L KEG KSIGVS Sbjct: 100 LEYLDLYLIHSPQVTKGD------------------IKGAWKELETLQKEGKTKSIGVSK 141 Query: 519 -----------------NFNSKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEAR 397 +FN +QL+ LL HATVKPVVNQ+ HPY+ + L E+ E + Sbjct: 142 QVYYQTIFFASLSDVWDSFNKEQLQELLAHATVKPVVNQILLHPYVITRTAPLLEYLEEQ 201 Query: 396 GVKITAYSPL-GSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIP 220 + YS L RP D P + IA+RL QVL+ + I + Sbjct: 202 NIVAEGYSTLIPLTSRPGGPVDKP-------VNQIAERLNVKPEQVLLAWSRAKRAIPVT 254 Query: 219 KSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRL 112 S ++R+ DV D L+ +DV ID G L Sbjct: 255 TSSRKARLEGYLDVGDITLTEDDVKAIDKAGAKGEL 290 >UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep: YvgN - Bacillus sp. NRRL B-14911 Length = 268 Score = 85.0 bits (201), Expect = 2e-15 Identities = 62/186 (33%), Positives = 92/186 (49%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLDL LIH+P ED K+Q + TW+ E + G +K+IGVSNF Sbjct: 111 YLDLLLIHFPI---ED----------KVQLKN-----TWEVFEEYYEAGKLKAIGVSNFE 152 Query: 510 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDD 331 L+ L + A VKP VNQ++ + K L + + A+ P+ + Sbjct: 153 ENHLDELKEFAKVKPAVNQIQINLKEPNKNLLAVLKDEEITPVAWGPMKA---------- 202 Query: 330 PQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSRED 151 + + L I K+ AQ+L++YQI G IVIPKS R ASN ++ DF+L+ ED Sbjct: 203 -EAHQKEALDEIGKIYHKSGAQILLKYQIQRGVIVIPKSHNRENQASNLELFDFELTAED 261 Query: 150 VALIDS 133 + I++ Sbjct: 262 IEKIEN 267 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 85.0 bits (201), Expect = 2e-15 Identities = 64/185 (34%), Positives = 90/185 (48%), Gaps = 4/185 (2%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 YLDLYL+H P + E KI S+ WKAME + GLV S+GVSNF Sbjct: 102 YLDLYLLHSPIPFYEK----------KIPISE-----GWKAMETALGTGLVHSVGVSNFR 146 Query: 510 SKQLERLLQHATVKPVVNQVECHP--YLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKP 337 LE LL+ +T+ P VNQ+E HP Y K L EFC+++G+ + Y PL R Sbjct: 147 IPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYGPLSPLVR----- 201 Query: 336 DDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVI--PKSVTRSRIASNFDVLDFKL 163 D Q K++ + + Q+L+++ G I I + R + NFD F L Sbjct: 202 -DAQGPVAEFTKSLESKYHVSDTQILLKWAYSKGVIPITTTSKIERMKECLNFD--SFTL 258 Query: 162 SREDV 148 + D+ Sbjct: 259 DKADI 263 >UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycetales|Rep: Aldo/keto reductase - Pichia stipitis (Yeast) Length = 323 Score = 84.6 bits (200), Expect = 2e-15 Identities = 68/194 (35%), Positives = 98/194 (50%), Gaps = 9/194 (4%) Frame = -3 Query: 690 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 511 Y+DL+LIH P ++E S T +S W + K G V+ IGVSNF+ Sbjct: 128 YVDLFLIHSP-FFEEKVSRGQTLESA------------WAEVIDAKKAGKVRHIGVSNFS 174 Query: 510 SKQLERLLQHA---TVKPVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPLGSPDRPW 346 + LER + A P VNQ+E HPYL + + +F + + I AY PL + R Sbjct: 175 KEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSPGIIKFAQENDILIEAYGPLSTLFRIK 234 Query: 345 AKPDDPQLMEDPKLKAI----ADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDV 178 D +ED LK + A++ GKT AQ+L+RY + + I S RI + +V Sbjct: 235 QNGVD---VEDHPLKELIPKLAEKYGKTDAQILLRYTLQKKILPITTSSKLDRIRQSLEV 291 Query: 177 LDFKLSREDVALID 136 +F++S EDVA ID Sbjct: 292 YNFEISDEDVAEID 305 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 83.4 bits (197), Expect = 5e-15 Identities = 47/162 (29%), Positives = 80/162 (49%), Gaps = 7/162 (4%) Frame = -3 Query: 585 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFC 406 ++ W+A+ L G +SIGVSNFN L + P NQ+E HP+ + L + Sbjct: 162 LEQWRALLELQANGKARSIGVSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYM 221 Query: 405 EARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKA-------IADRLGKTVAQVLIRYQ 247 + + AYS L P W + + ++KA +A++ G + AQ+L+R+ Sbjct: 222 DQHAIAPIAYSSL-VPLSTWRTKEGQASAKTDEMKAAGTTFRDMAEKYGVSEAQLLLRWG 280 Query: 246 IDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCG 121 + +G V+PKS+ R+ N D+ F + D+A + + D G Sbjct: 281 VQNGYAVLPKSMNPDRMRQNIDLFSFSIDDTDMAKMATMDQG 322 >UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3; Saccharomycetales|Rep: Conjugated polyketone reductase C1 - Candida parapsilosis (Yeast) Length = 304 Score = 83.4 bits (197), Expect = 5e-15 Identities = 55/185 (29%), Positives = 92/185 (49%), Gaps = 3/185 (1%) Frame = -3 Query: 696 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 517 ++Y+DLYLIH+P ++ D V+ W+ +E EGL ++IGVSN Sbjct: 116 LEYVDLYLIHFPYISEKSHGF--------------DLVEAWRYLERAKNEGLARNIGVSN 161 Query: 516 FNSKQLERLLQHATVK-PVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPLGSPDRPW 346 F + L+ +L T PVVNQ+E YL + + E+ + +G+ I AY PLG + Sbjct: 162 FTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGR 221 Query: 345 AKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFK 166 P D L ++++ + Q+L+R+ + G + I + RI ++ DF+ Sbjct: 222 PGP------LDKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFE 275 Query: 165 LSRED 151 L +ED Sbjct: 276 LDKED 280 >UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A - Sulfolobus acidocaldarius Length = 267 Score = 83.0 bits (196), Expect = 6e-15 Identities = 69/187 (36%), Positives = 95/187 (50%), Gaps = 4/187 (2%) Frame = -3 Query: 699 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 520 N +Y+DLYLIHWP DV +T AME L+ G+V+ IGVS Sbjct: 103 NTKYIDLYLIHWPNP-------------------DVKVEETISAMEKLIDMGVVRCIGVS 143 Query: 519 NFNSKQLERLLQHATVK--PVVNQVECHPY-LNQKR-LKEFCEARGVKITAYSPLGSPDR 352 NF+ K L++ + H+T K V NQ++ Y L +R + F E V I AYSPLG Sbjct: 144 NFDVKLLDQAI-HSTKKYEIVANQIQYSIYRLTPERDVIPFAEKNKVTIIAYSPLG---- 198 Query: 351 PWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLD 172 + + +LK IA + GKT AQV + Y + +I IPK+V ++ I DV+ Sbjct: 199 ------QGSISSESRLKDIALKYGKTQAQVALAY-LKRRSIPIPKAVQKTHIDEIADVMK 251 Query: 171 FKLSRED 151 F L ED Sbjct: 252 FDLRDED 258 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 82.6 bits (195), Expect = 8e-15 Identities = 54/160 (33%), Positives = 80/160 (50%), Gaps = 1/160 (0%) Frame = -3 Query: 588 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 409 YV+++ A+ + G ++S+ V+NF + L ++ + PV+NQVE HP +Q + Sbjct: 129 YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQRAV 188 Query: 408 CEARGVKITAYSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNI 229 GV A+SPLG D + + IA KT AQV +R+ G Sbjct: 189 DRELGVVTEAWSPLGRGDS----------LNAEAITLIAQCYEKTPAQVTLRWIHQLGCS 238 Query: 228 VIPKSVTRSRIASNFDVLDFKLSREDVALIDSFD-CGGRL 112 V+PKS R N D+ DF+L+ ED+ I S D GGRL Sbjct: 239 VVPKSANPQRQRENLDIFDFELNTEDMNSITSLDEQGGRL 278 >UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo sapiens (Human) Length = 188 Score = 82.6 bits (195), Expect = 8e-15 Identities = 46/96 (47%), Positives = 59/96 (61%), Gaps = 3/96 (3%) Frame = -3 Query: 612 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHP 439 +I F VD TW+AME KSIGVSNFN + LE +L +K PV NQVECHP Sbjct: 55 EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHP 106 Query: 438 YLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPD 334 Y NQ++L +FC + + + AYS LGS + PW P+ Sbjct: 107 YFNQRKLLDFC--KDIVLVAYSALGSHREEPWVDPN 140 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 683,651,923 Number of Sequences: 1657284 Number of extensions: 14488215 Number of successful extensions: 61169 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 55740 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 60453 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 55785129165 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -