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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV11a18f
         (634 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|...   286   3e-76
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1...   269   4e-71
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ...   264   1e-69
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ...   259   3e-68
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ...   252   7e-66
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|...   243   3e-63
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA...   242   6e-63
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ...   230   2e-59
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi...   229   4e-59
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb...   226   3e-58
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep...   226   3e-58
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ...   223   2e-57
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti...   121   4e-55
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n...   216   4e-55
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;...   215   7e-55
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18...   215   7e-55
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l...   214   2e-54
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi...   213   4e-54
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p...   212   7e-54
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ...   211   1e-53
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve...   211   1e-53
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ...   207   1e-52
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13...   207   1e-52
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+...   206   3e-52
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:...   205   6e-52
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica...   202   6e-51
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=...   198   7e-50
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt...   198   7e-50
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin...   197   2e-49
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium...   197   2e-49
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E...   197   2e-49
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A...   196   3e-49
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ...   196   5e-49
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ...   194   1e-48
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+...   194   2e-48
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl...   193   3e-48
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini...   191   1e-47
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct...   190   2e-47
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|...   190   2e-47
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal...   189   4e-47
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ...   184   1e-45
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=...   184   2e-45
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re...   182   5e-45
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ...   182   6e-45
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R...   180   3e-44
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam...   177   2e-43
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct...   176   3e-43
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10...   176   3e-43
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ...   176   4e-43
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:...   175   6e-43
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ...   175   7e-43
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27...   175   7e-43
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu...   174   1e-42
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste...   174   1e-42
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several...   173   2e-42
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti...   172   5e-42
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam...   171   9e-42
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ...   171   1e-41
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ...   170   3e-41
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ...   169   5e-41
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ...   169   6e-41
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R...   169   6e-41
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ...   169   6e-41
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons...   168   8e-41
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str...   168   8e-41
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red...   167   2e-40
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ...   167   2e-40
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam...   167   2e-40
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri...   167   3e-40
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r...   166   4e-40
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   165   6e-40
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno...   165   6e-40
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di...   165   1e-39
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt...   164   2e-39
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA...   162   5e-39
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r...   162   5e-39
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota...   162   5e-39
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=...   162   5e-39
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   161   1e-38
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor...   160   3e-38
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep...   160   3e-38
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org...   159   5e-38
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea...   159   7e-38
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio...   157   2e-37
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB...   157   2e-37
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d...   157   2e-37
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald...   157   3e-37
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   156   5e-37
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ...   155   1e-36
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ...   154   1e-36
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n...   154   1e-36
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ...   154   2e-36
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb...   153   3e-36
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   153   3e-36
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7...   153   3e-36
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ...   153   3e-36
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy...   153   3e-36
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase...   153   3e-36
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str...   153   3e-36
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re...   152   6e-36
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   152   8e-36
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;...   151   1e-35
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam...   151   1e-35
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc...   151   2e-35
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam...   150   3e-35
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re...   149   5e-35
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or...   149   5e-35
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l...   149   5e-35
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;...   149   7e-35
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct...   148   1e-34
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ...   147   2e-34
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ...   147   2e-34
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ...   147   2e-34
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,...   147   2e-34
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar...   146   3e-34
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ...   146   4e-34
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ...   146   4e-34
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red...   145   9e-34
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|...   145   9e-34
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ...   145   9e-34
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam...   144   2e-33
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl...   144   2e-33
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n...   142   5e-33
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ...   142   6e-33
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R...   142   8e-33
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   141   1e-32
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ...   140   2e-32
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta...   140   2e-32
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac...   140   3e-32
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ...   140   3e-32
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   139   4e-32
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta...   138   8e-32
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam...   138   1e-31
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;...   137   2e-31
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r...   137   2e-31
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7...   136   3e-31
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...   136   3e-31
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li...   136   4e-31
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec...   136   4e-31
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ...   136   5e-31
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ...   134   2e-30
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop...   133   3e-30
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ...   132   5e-30
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ...   132   7e-30
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct...   132   9e-30
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   132   9e-30
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac...   131   1e-29
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ...   130   2e-29
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   130   2e-29
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=...   130   2e-29
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh...   130   2e-29
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria...   130   3e-29
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep...   130   4e-29
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ...   130   4e-29
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re...   129   5e-29
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E...   129   6e-29
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea...   129   6e-29
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:...   129   6e-29
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag...   128   8e-29
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;...   127   2e-28
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam...   127   2e-28
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct...   127   3e-28
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve...   127   3e-28
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci...   126   3e-28
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac...   126   3e-28
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S...   126   3e-28
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ...   126   4e-28
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:...   126   6e-28
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r...   126   6e-28
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam...   126   6e-28
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom...   126   6e-28
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   125   8e-28
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep...   124   2e-27
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=...   124   2e-27
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ...   124   2e-27
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;...   124   2e-27
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ...   124   2e-27
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy...   124   2e-27
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...   123   4e-27
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe...   123   4e-27
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ...   123   4e-27
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:...   122   7e-27
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re...   122   7e-27
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1...   122   1e-26
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ...   121   1e-26
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li...   119   5e-26
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   119   5e-26
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi...   119   7e-26
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam...   118   9e-26
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ...   118   9e-26
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled...   118   2e-25
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter...   117   2e-25
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami...   117   3e-25
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;...   117   3e-25
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac...   116   4e-25
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101...   116   6e-25
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop...   116   6e-25
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium...   116   6e-25
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str...   116   6e-25
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ...   116   6e-25
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom...    71   8e-25
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ...   115   8e-25
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...   115   1e-24
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r...   115   1e-24
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ...   105   1e-24
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ...   114   1e-24
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act...   114   1e-24
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal...   114   1e-24
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O...   114   2e-24
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ...   113   3e-24
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri...   113   4e-24
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ...   112   6e-24
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r...   112   6e-24
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc...   112   6e-24
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami...   112   8e-24
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri...   111   1e-23
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4...   111   2e-23
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba...   111   2e-23
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep...   110   2e-23
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez...   110   2e-23
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter...   110   3e-23
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ...   110   3e-23
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ...   109   5e-23
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ...   109   7e-23
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li...   108   9e-23
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba...   108   9e-23
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil...   108   1e-22
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=...   107   2e-22
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ...   106   4e-22
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta...   106   5e-22
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac...   105   7e-22
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace...   105   1e-21
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm...   104   2e-21
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ...   104   2e-21
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami...   104   2e-21
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba...   103   3e-21
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ...   103   3e-21
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc...   103   3e-21
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ...   103   4e-21
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami...   103   5e-21
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la...   103   5e-21
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba...   102   6e-21
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik...   102   6e-21
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1...   101   1e-20
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   101   1e-20
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo...   101   2e-20
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ...   100   3e-20
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ...   100   6e-20
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ...   100   6e-20
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam...    99   8e-20
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    99   8e-20
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n...    99   8e-20
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try...    99   8e-20
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas...    99   1e-19
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;...    98   1e-19
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac...    97   2e-19
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob...    97   3e-19
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve...    97   4e-19
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta...    95   1e-18
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam...    95   1e-18
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re...    95   1e-18
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re...    95   2e-18
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    94   2e-18
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=...    93   5e-18
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil...    92   1e-17
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc...    90   4e-17
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ...    90   4e-17
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ...    90   5e-17
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    90   5e-17
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3...    88   1e-16
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ...    88   2e-16
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ...    88   2e-16
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct...    87   3e-16
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep...    87   3e-16
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ...    87   4e-16
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red...    86   6e-16
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium...    85   1e-15
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;...    85   2e-15
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    82   9e-15
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei...    82   1e-14
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    82   1e-14
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ...    81   2e-14
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap...    81   2e-14
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ...    81   2e-14
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    81   2e-14
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v...    81   3e-14
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1...    79   9e-14
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ...    79   9e-14
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet...    79   9e-14
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte...    79   1e-13
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054...    79   1e-13
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc...    78   2e-13
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez...    77   3e-13
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,...    77   5e-13
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere...    76   6e-13
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve...    75   1e-12
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ...    75   2e-12
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    74   2e-12
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam...    74   3e-12
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ...    73   8e-12
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami...    73   8e-12
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ...    72   1e-11
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|...    71   2e-11
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ...    71   2e-11
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata...    71   2e-11
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ...    70   5e-11
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017...    69   7e-11
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep...    69   1e-10
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam...    68   2e-10
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc...    68   2e-10
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa...    68   2e-10
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ...    68   2e-10
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|...    67   3e-10
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ...    67   4e-10
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ...    66   5e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc...    66   9e-10
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    65   1e-09
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative...    65   2e-09
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;...    64   2e-09
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap...    64   2e-09
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac...    64   2e-09
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel...    64   3e-09
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella...    64   4e-09
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto...    64   4e-09
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ...    63   5e-09
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3....    62   8e-09
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ...    62   8e-09
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n...    62   8e-09
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D...    62   8e-09
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc...    62   8e-09
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ...    62   1e-08
UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ...    62   1e-08
UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|...    62   1e-08
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta...    61   2e-08
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep...    61   2e-08
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno...    61   2e-08
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica...    60   3e-08
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su...    60   6e-08
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ...    59   8e-08
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel...    59   1e-07
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola...    58   2e-07
UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ...    57   4e-07
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico...    56   5e-07
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1...    56   5e-07
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r...    56   7e-07
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ...    56   7e-07
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ...    56   9e-07
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam...    55   1e-06
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep...    54   2e-06
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The...    54   2e-06
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga...    53   7e-06
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p...    52   9e-06
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000...    52   2e-05
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt...    52   2e-05
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep...    51   2e-05
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O...    51   3e-05
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy...    51   3e-05
UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth...    51   3e-05
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria...    50   4e-05
UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ...    50   4e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;...    50   5e-05
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve...    50   5e-05
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu...    50   6e-05
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia...    50   6e-05
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam...    49   8e-05
UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2...    49   1e-04
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|...    49   1e-04
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    48   1e-04
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:...    48   1e-04
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym...    48   1e-04
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B...    48   2e-04
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu...    48   2e-04
UniRef50_Q966L2 Cluster: Putative uncharacterized protein; n=2; ...    48   2e-04
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p...    48   2e-04
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul...    48   2e-04
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam...    48   2e-04
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase...    47   3e-04
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam...    47   3e-04
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei...    47   3e-04
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C...    47   4e-04
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:...    47   4e-04
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4...    47   4e-04
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ...    47   4e-04
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ...    46   6e-04
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular...    46   6e-04
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina...    46   6e-04
UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ...    40   6e-04
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob...    46   8e-04
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam...    46   8e-04
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac...    46   8e-04
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    46   8e-04
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ...    46   0.001
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    46   0.001
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr...    45   0.001
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact...    45   0.001
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669...    45   0.001
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy...    45   0.002
UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter...    44   0.002
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ...    44   0.002
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam...    44   0.002
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga...    44   0.002
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia...    44   0.002
UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su...    44   0.002
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms...    44   0.002
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ...    44   0.003
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri...    44   0.004
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p...    44   0.004
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ...    44   0.004
UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno...    44   0.004
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym...    43   0.005
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r...    43   0.005
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s...    43   0.005
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium...    43   0.005
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ...    43   0.005
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa...    43   0.005
UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-...    43   0.007
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam...    43   0.007
UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri...    43   0.007
UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha...    43   0.007
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp...    43   0.007
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De...    42   0.009
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ...    42   0.009
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr...    42   0.009
UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig...    42   0.009
UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba...    42   0.009
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam...    42   0.009
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos...    42   0.009
UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires...    42   0.012
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter...    42   0.012
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R...    42   0.012
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam...    42   0.012
UniRef50_A2TIR8 Cluster: Receptor for egg jelly protein 9; n=9; ...    42   0.012
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami...    42   0.012
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=...    42   0.012
UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy...    42   0.016
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy...    42   0.016
UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ...    42   0.016
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R...    42   0.016
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...    42   0.016
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc...    42   0.016
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn...    42   0.016
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ...    42   0.016
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh...    41   0.022
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid...    41   0.022
UniRef50_Q41CR8 Cluster: Aldo/keto reductase; n=1; Exiguobacteri...    41   0.022
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma...    41   0.022
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy...    41   0.022
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu...    41   0.022
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1...    41   0.022
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi...    41   0.028
UniRef50_Q3A7S5 Cluster: Predicted oxidoreductases of the aldo/k...    41   0.028
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    41   0.028
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ...    41   0.028
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal...    41   0.028
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ...    41   0.028
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu...    41   0.028
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f...    40   0.038
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re...    40   0.038
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a...    40   0.038
UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla...    40   0.038
UniRef50_Q6WN58 Cluster: Glutamate-cysteine ligase modifier subu...    40   0.038
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ...    40   0.038
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    40   0.038
UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba...    40   0.050
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter...    40   0.050
UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga...    40   0.050
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b...    40   0.050
UniRef50_Q4QEB9 Cluster: Protein kinase, putative; n=3; Leishman...    40   0.050
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ...    40   0.050
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido...    40   0.050
UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2; Des...    40   0.050
UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|...    40   0.050
UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase fam...    40   0.066
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid...    40   0.066
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ...    40   0.066
UniRef50_A7RWF3 Cluster: Predicted protein; n=1; Nematostella ve...    40   0.066
UniRef50_P48507 Cluster: Glutamate--cysteine ligase regulatory s...    40   0.066
UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact...    39   0.087
UniRef50_Q5FJ72 Cluster: Predicted oxidoreductase; n=1; Lactobac...    39   0.087
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ...    39   0.087
UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ...    39   0.087
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ...    39   0.087
UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de...    39   0.087
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ...    39   0.087
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob...    39   0.087
UniRef50_UPI0000605361 Cluster: PREDICTED: hypothetical protein;...    39   0.11 
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole...    39   0.11 
UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro...    39   0.11 
UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St...    39   0.11 
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ...    39   0.11 
UniRef50_Q17N98 Cluster: Gamma-glutamylcysteine synthetase, puta...    39   0.11 
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ...    39   0.11 
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis...    38   0.15 
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|...    38   0.15 
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki...    38   0.15 
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve...    38   0.15 

>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
           Endopterygota|Rep: ENSANGP00000031808 - Anopheles
           gambiae str. PEST
          Length = 316

 Score =  286 bits (701), Expect = 3e-76
 Identities = 128/197 (64%), Positives = 150/197 (76%), Gaps = 1/197 (0%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           +P   F NG +IP+FGLGTW S PG+V QAVKDAID+GYRHIDCA+VY NE EVGE I +
Sbjct: 6   VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
           KI EGVV REDLF+TSKLWNTFHRPDLV GA + TL NL + YLDLYLIHWP  Y+E   
Sbjct: 66  KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125

Query: 407 LFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
           LFP    GK   FSD DYVDTW  ME LV  GLV++IGVSNFN+KQ++R+L  A + P  
Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPAT 185

Query: 584 NQVECHPYLNQKRLKEF 634
           NQ+ECHPYL+Q ++  F
Sbjct: 186 NQIECHPYLHQSKITTF 202


>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
           GA19341-PA - Drosophila pseudoobscura (Fruit fly)
          Length = 315

 Score =  269 bits (659), Expect = 4e-71
 Identities = 121/193 (62%), Positives = 148/193 (76%), Gaps = 1/193 (0%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P    ++G  +P+ GLGTW+S P  V QAVKDAIDIGYRH DCA++YGNE  VG AI  K
Sbjct: 4   PSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIREK 63

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           I+EG+VTR++LFITSKLWNTFH+P+LVR A + +L NL + YLDLYL+HWP AYK   +L
Sbjct: 64  IQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGDNL 123

Query: 410 FPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
           +PT   +GK  F D+DY+DTWKAME LV  GLV +IGVSNFN KQ+ RLL  A +KPV+ 
Sbjct: 124 YPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPVML 183

Query: 587 QVECHPYLNQKRL 625
           Q+ECHPYL QK L
Sbjct: 184 QIECHPYLRQKSL 196


>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 322

 Score =  264 bits (647), Expect = 1e-69
 Identities = 120/194 (61%), Positives = 151/194 (77%), Gaps = 2/194 (1%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P    +NG+ +P+ GLGTW+S P  VTQAVKDAIDIGYRH DCA++YGNE +VG A+  K
Sbjct: 4   PNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREK 63

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE-DGS 406
           + EGVVTR++LFITSKLWNT H+PDLVR A + ++ NL V+YL+LYL+HWP AYK    +
Sbjct: 64  MDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDN 123

Query: 407 LFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
           L+PT   + K  F D+DYVDTW+AME LV EGL ++IGVSNFN +Q+ RLL  A +KPVV
Sbjct: 124 LYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVV 183

Query: 584 NQVECHPYLNQKRL 625
            Q+ECHPYL+QK L
Sbjct: 184 LQIECHPYLSQKPL 197


>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
           Aldose reductase - Mus musculus (Mouse)
          Length = 316

 Score =  259 bits (635), Expect = 3e-68
 Identities = 120/192 (62%), Positives = 143/192 (74%), Gaps = 2/192 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NNG  +P  GLGTWKS PG+VT+AVK AID+GYRHIDCA VY NEKEVG A+  K+KE V
Sbjct: 8   NNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQV 67

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           V R+DLFI SKLW TFH   +V+GA Q+TL +L + YLDLYLIHWP  +K     FP D 
Sbjct: 68  VKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDA 127

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVEC 598
           SG +  SD D+VDTW AME LV EGLVK+IGVSNFN  Q+ER+L    +  KP VNQ+EC
Sbjct: 128 SGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIEC 187

Query: 599 HPYLNQKRLKEF 634
           HPYL Q++L E+
Sbjct: 188 HPYLTQEKLIEY 199


>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
           Aldose reductase - Homo sapiens (Human)
          Length = 316

 Score =  252 bits (616), Expect = 7e-66
 Identities = 114/192 (59%), Positives = 143/192 (74%), Gaps = 2/192 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NNG  +P+ GLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI  K++E V
Sbjct: 8   NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           V RE+LFI SKLW T+H   LV+GA Q+TL +L + YLDLYLIHWP  +K     FP D+
Sbjct: 68  VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVEC 598
           SG +  SD + +DTW AME LV EGLVK+IG+SNFN  Q+E +L    +  KP VNQ+EC
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187

Query: 599 HPYLNQKRLKEF 634
           HPYL Q++L ++
Sbjct: 188 HPYLTQEKLIQY 199


>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
           Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
           (Mouse)
          Length = 316

 Score =  243 bits (594), Expect = 3e-63
 Identities = 114/195 (58%), Positives = 137/195 (70%), Gaps = 2/195 (1%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           VT   G  +P+ GLGTWKS P +V +AVK AID GYRHIDCAYVY NE EVGEAI  KI+
Sbjct: 5   VTLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ 64

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
           E  V REDLFI SKLW+TF    LV+ A Q TL +L + YLDLYLIHWPQ ++      P
Sbjct: 65  EKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLP 124

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQ 589
           TD  G I  S   ++D W+AME LV +GLVK++GVSNFN  Q+ERLL    +  KPV NQ
Sbjct: 125 TDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQ 184

Query: 590 VECHPYLNQKRLKEF 634
           VECHPYL Q++L ++
Sbjct: 185 VECHPYLTQEKLTQY 199


>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA10458-PA - Nasonia vitripennis
          Length = 569

 Score =  242 bits (592), Expect = 6e-63
 Identities = 108/196 (55%), Positives = 145/196 (73%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           +P VTFN+G  +P+ GLGT+ SKPGEV +AVK AI++GYRH+D A+ Y NEKE+G AI  
Sbjct: 3   VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
           KI +G + RED+F+T+KLW   H+ D V  A +++L+NL   Y+DL+L+HWP A+K   +
Sbjct: 63  KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
           L P D +GKI+FSD DY++TWK ME   ++GL +SIG+SNFNS+Q+ RLL  A +KPV N
Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNN 182

Query: 587 QVECHPYLNQKRLKEF 634
           QVE    LNQK L EF
Sbjct: 183 QVEVTMNLNQKPLIEF 198



 Score =  167 bits (406), Expect = 2e-40
 Identities = 84/159 (52%), Positives = 109/159 (68%), Gaps = 1/159 (0%)
 Frame = +2

Query: 161 YRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDN 340
           YRHID AY+Y NEK +G AI  KIK+G V REDLF+T+KL    H+   V  A +++L++
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360

Query: 341 LNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 517
           L + Y+DLYLIHWP + Y         + SGK+  SD DY++TWK ME   ++GL +SIG
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQGLARSIG 416

Query: 518 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
           VSNFNS+Q+ RLL+ A +KPV NQVE    LNQK L EF
Sbjct: 417 VSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEF 455


>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 316

 Score =  230 bits (563), Expect = 2e-59
 Identities = 103/190 (54%), Positives = 132/190 (69%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N+G +IP  GLGTW+SKPGEV  A+K A+  GYRHIDCA+VY N+KEVGEA+   + EG 
Sbjct: 8   NSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEGK 67

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           V RE+LFITSK+WNTFH        +   L +L + Y+DL LIHWPQ Y E   LFP  +
Sbjct: 68  VKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAGE 127

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
           +GK+++SDVDY++TWKA E   K G  +SIG+SNF   Q++R+   A VKP   QVE HP
Sbjct: 128 NGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHP 187

Query: 605 YLNQKRLKEF 634
           Y  Q +L+EF
Sbjct: 188 YFTQVKLREF 197


>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
           Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
           sapiens (Human)
          Length = 325

 Score =  229 bits (560), Expect = 4e-59
 Identities = 101/191 (52%), Positives = 140/191 (73%), Gaps = 1/191 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           V  + G+ +P+ GLGTWKS+PG+V  AVK A+ +GYRHIDCA +YGNE E+GEA+   + 
Sbjct: 6   VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65

Query: 236 EG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
            G  V RE+LF+TSKLWNT H P+ V  AL++TL +L ++YLDLYL+HWP A++   + F
Sbjct: 66  PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
           P +  G I +    Y +TWKA+E LV +GLV+++G+SNFNS+Q++ +L  A+V+P V QV
Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQV 185

Query: 593 ECHPYLNQKRL 625
           ECHPYL Q  L
Sbjct: 186 ECHPYLAQNEL 196


>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
           str. PEST
          Length = 319

 Score =  226 bits (553), Expect = 3e-58
 Identities = 108/205 (52%), Positives = 147/205 (71%), Gaps = 5/205 (2%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           M+ ++P V F+NG  IPV G GT+ ++ G+  + VK AID+GYRHID A++Y NE E+G+
Sbjct: 1   MSTQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQ 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
           AI  KI EGV+ RED+F+T+KLWNTFH P  V  A + + D L++ Y+DL+L+H P   +
Sbjct: 61  AIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQ 120

Query: 395 EDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE-GLVKSIGVSNFNSKQLERLLQ 559
             G     + P D +G + FSDVDYV+TWKAME LV   G V+SIG+SNFNS+Q+ER+LQ
Sbjct: 121 FSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQ 180

Query: 560 HATVKPVVNQVECHPYLNQKRLKEF 634
            ATVKPV NQVE +P  +Q++L  F
Sbjct: 181 IATVKPVNNQVEANPGYDQRKLIAF 205


>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
           Aldo-keto reductase - Aedes aegypti (Yellowfever
           mosquito)
          Length = 324

 Score =  226 bits (553), Expect = 3e-58
 Identities = 114/200 (57%), Positives = 139/200 (69%), Gaps = 4/200 (2%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP V  NNG  +P  GLGT  SK  E  +AV  AID G+RHID AY Y NE  VG AI +
Sbjct: 6   IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 403
           KI+EGVVTRE+LF+T+KLWNTFH PD V  A  ++L++L + Y+DL+LIH P  Y+ +G 
Sbjct: 66  KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125

Query: 404 ---SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
                 P D +G +  SD DYVDTWKAME L++ G V SIGVSNFNS+QLER+L +  VK
Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVK 185

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           PV NQVEC   +NQK L EF
Sbjct: 186 PVTNQVECSARINQKLLIEF 205


>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 321

 Score =  223 bits (546), Expect = 2e-57
 Identities = 102/202 (50%), Positives = 139/202 (68%), Gaps = 2/202 (0%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 208
           M+PK+  +T ++G  +PV GLGTW+  + P EV  AVK AID GYRH DCA  YGNE E+
Sbjct: 1   MSPKVDEITLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEI 60

Query: 209 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388
           G+AI  KI +GVV REDLF+ +K+WN   + +LV  A + +L  L + Y+DLYL+HWP +
Sbjct: 61  GKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFS 120

Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
           Y              +   +VDY++TW+ ME  +K GL +SIGVSNFNS+QL RLL+ A+
Sbjct: 121 YPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESAS 180

Query: 569 VKPVVNQVECHPYLNQKRLKEF 634
           +KPV+NQ+E H  LNQK+L+EF
Sbjct: 181 IKPVMNQIELHINLNQKKLREF 202


>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 284

 Score =  121 bits (291), Expect(2) = 4e-55
 Identities = 57/87 (65%), Positives = 67/87 (77%), Gaps = 2/87 (2%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           M+PK P+V  NNG  +PV GLGTW SK GE  +A+K AID GYRHID AY Y NEKEVGE
Sbjct: 1   MSPKAPMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGE 60

Query: 215 AITSKIKEGVVTREDLFITSKL--WNT 289
           AI +KI+EGVV REDLF+T+K   W+T
Sbjct: 61  AIRAKIEEGVVCREDLFVTTKFIDWDT 87



 Score =  116 bits (280), Expect(2) = 4e-55
 Identities = 52/77 (67%), Positives = 62/77 (80%)
 Frame = +2

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
           +L P D  GK+QFSDVDY+DTWKAME L+K G VKSIGVSNFNS+Q+ RLL    +KPV 
Sbjct: 89  NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148

Query: 584 NQVECHPYLNQKRLKEF 634
           NQVEC+P LNQ++L EF
Sbjct: 149 NQVECNPSLNQRKLTEF 165


>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
           n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
           dehydrogenase - Xenopus tropicalis (Western clawed frog)
           (Silurana tropicalis)
          Length = 324

 Score =  216 bits (527), Expect = 4e-55
 Identities = 103/198 (52%), Positives = 134/198 (67%), Gaps = 5/198 (2%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTW---KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           V  N+G  +PV G GT+   K       +  K AID+GYRHIDCA++YGNE+EVG AI +
Sbjct: 9   VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRA 68

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
           KI +G V RED+F T KLW+T H P+ VR AL+++L +L + Y+DL++IH P  +K    
Sbjct: 69  KIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDD 128

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPV 580
           LFP D++GK  + + D  DTWKA+E     GLV+SIGVSNFN KQLE +L    +  KPV
Sbjct: 129 LFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPV 188

Query: 581 VNQVECHPYLNQKRLKEF 634
            NQVECH YLNQ +L EF
Sbjct: 189 CNQVECHVYLNQSKLLEF 206


>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 333

 Score =  215 bits (525), Expect = 7e-55
 Identities = 99/195 (50%), Positives = 133/195 (68%), Gaps = 2/195 (1%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           VT  +G  +P+ GLGTWK K  EV  A+  A+D GYRH DCA +YGNEKEVG A+   ++
Sbjct: 5   VTLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQ 64

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 409
              + RED+FIT+K+WNTFH  + V      +L +L + Y+DLY++HWP  ++  G   +
Sbjct: 65  RLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVM 124

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
           FP  ++G I +SDV Y++TW AME LVK G  KS+G+SNFNSKQL+ +LQH+TV P V Q
Sbjct: 125 FPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQ 184

Query: 590 VECHPYLNQKRLKEF 634
           VE HP+L Q  L  F
Sbjct: 185 VESHPFLPQVELLNF 199


>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
           n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
           C18 - Mus musculus (Mouse)
          Length = 323

 Score =  215 bits (525), Expect = 7e-55
 Identities = 103/202 (50%), Positives = 139/202 (68%), Gaps = 5/202 (2%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKE 205
           M  KI  +  N+G +IPV G GT+ ++     +  ++ K AID+G+ HIDC+++Y NE+E
Sbjct: 1   MNSKIQKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEE 60

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
           +G+AI SKI++G V RED+F TSKLW+T HRP+LVR +L+ +L  LN+ Y+DLYLIH+P 
Sbjct: 61  IGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPV 120

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
           + K    L P D+ G + F  VD  DTW+AME     GL KSIGVSNFN +QLE +L   
Sbjct: 121 SLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 566 TV--KPVVNQVECHPYLNQKRL 625
            +  KPV NQVECH YLNQ +L
Sbjct: 181 GLKYKPVCNQVECHLYLNQSKL 202


>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
           protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
           family 1 member C-like protein 2 - Homo sapiens (Human)
          Length = 320

 Score =  214 bits (522), Expect = 2e-54
 Identities = 110/206 (53%), Positives = 133/206 (64%), Gaps = 21/206 (10%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           IP  GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG  I  KIKEG V RED
Sbjct: 4   IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63

Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL-- 409
           LFI +KLW T H+  LV  A +++L  L + YLDLYLIHWP  +K            L  
Sbjct: 64  LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123

Query: 410 ---------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
                     P D+S  +  SD D++DTW+AME LV  GLVK+IGVSNFN +QLERLL  
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183

Query: 563 ATV--KPVVNQVECHPYLNQKRLKEF 634
             +  KP+ NQ+ECHPYL QK L  F
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISF 209


>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
           division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
           candidate division TM7 genomosp. GTL1
          Length = 299

 Score =  213 bits (519), Expect = 4e-54
 Identities = 100/193 (51%), Positives = 130/193 (67%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +T  N +T+P+ G GTW+   G     V+ AI  GYRHIDCA +YGNEKEVGE I   I 
Sbjct: 4   LTLRNKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTID 63

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
           +GVV REDLF+TSKLWNT H    V  A ++TL++L + YLDLYLIHW  A++   +L P
Sbjct: 64  QGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEP 123

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
            D  G  +FS +   +TW+AME LV++GLVKS+GV+NF +  L  LL +A +KP V+Q+E
Sbjct: 124 LDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIE 183

Query: 596 CHPYLNQKRLKEF 634
            HPYL Q  L  F
Sbjct: 184 LHPYLAQNDLVAF 196


>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
           Drosophila melanogaster (Fruit fly)
          Length = 311

 Score =  212 bits (517), Expect = 7e-54
 Identities = 96/194 (49%), Positives = 134/194 (69%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P +  NNG  +P  GLGTWKS   +   + + A+D+GYRH+D A+VY NE EVG+AI+ K
Sbjct: 6   PTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEK 65

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           I EGVVTRE++F+T+KL    H P LV  A + +L NL ++Y+DLYL+H P   K     
Sbjct: 66  IAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHND- 124

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
             ++  G ++ +DVDY+DTW+ ME LV  GL +SIG+SNFN+ Q ER+L +  ++PVVNQ
Sbjct: 125 --SNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQ 182

Query: 590 VECHPYLNQKRLKE 631
           VECHP   Q++L+E
Sbjct: 183 VECHPGFQQRQLRE 196


>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
           discoideum|Rep: Aldehyde reductase - Dictyostelium
           discoideum AX4
          Length = 297

 Score =  211 bits (515), Expect = 1e-53
 Identities = 106/196 (54%), Positives = 134/196 (68%), Gaps = 1/196 (0%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P    ++G  IP+ G GTWK++   V +AV+ A+D GYRHIDCA VY NEKEVGEA T K
Sbjct: 3   PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62

Query: 230 IK-EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
              E  V RED+FITSKLWNTFH+ + VR AL+ TL +L +QYLDLYL+HWP A++   +
Sbjct: 63  FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
              T  SG  Q   V   +TW+ ME LV  GLVKSIG+SNFN + L  +L +A +KP  N
Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAAN 179

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HP+L+Q  LK+F
Sbjct: 180 QVELHPFLSQPELKKF 195


>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 323

 Score =  211 bits (515), Expect = 1e-53
 Identities = 105/200 (52%), Positives = 135/200 (67%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MA K      N G +IP   LGTW+S   EV  AV+ AI++GYRHIDCA +YGNE E+GE
Sbjct: 1   MAMKQIFCKLNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGE 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
           A++  + EG V RE+LF+TSKLW   H PD V  A Q TL NL + YLDLYLIH P A+K
Sbjct: 61  ALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFK 120

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
           +   L  +   G I ++     +TW+AME LV +GL K+IGVSNF+ K+L +LL+ A++ 
Sbjct: 121 KGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIV 180

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P  NQVE HPYL Q++LKEF
Sbjct: 181 PACNQVELHPYLPQEKLKEF 200


>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
           protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "AKR1B1 protein. - Takifugu rubripes
          Length = 330

 Score =  207 bits (506), Expect = 1e-52
 Identities = 107/222 (48%), Positives = 139/222 (62%), Gaps = 26/222 (11%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP VT N G  +PV GLGTWKS  G  T+AVK AI  GYRHID AYVY NE EVG  + +
Sbjct: 2   IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ------- 385
            I +GVV RE+LFI SKLW TFH P LVRGA ++TL +LN+ Y+DLYL+H+P        
Sbjct: 62  MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121

Query: 386 -----------AYKEDGSL------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 514
                       +++   L      FP D+  ++      ++DTW+AME LV +GL K+I
Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAI 181

Query: 515 GVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEF 634
           G+SNFN  Q+E +L    +  KP  NQ+ECHP+LNQ++L  F
Sbjct: 182 GISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHF 223


>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
           n=11; Theria|Rep: Aldo-keto reductase family 1 member
           C13 - Mus musculus (Mouse)
          Length = 323

 Score =  207 bits (506), Expect = 1e-52
 Identities = 101/205 (49%), Positives = 139/205 (67%), Gaps = 5/205 (2%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDA---IDIGYRHIDCAYVYGNEKE 205
           M+ K   V  N+G  IP  G GT+K K    +++++ A   +D+GYRH+D AY Y  E+E
Sbjct: 1   MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEE 60

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
           +G+AI SKIK GVV REDLFIT+KLW T  RP+LV+ AL+++L  L + Y+DLY++H+P 
Sbjct: 61  IGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPV 120

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
             K   + FP ++ GK     VD+ DTW+ +E     GLVKSIGVSNFN +QLER+L   
Sbjct: 121 PMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKP 180

Query: 566 TV--KPVVNQVECHPYLNQKRLKEF 634
            +  KPV NQVECH YLNQ++L ++
Sbjct: 181 GLKYKPVCNQVECHLYLNQRKLLDY 205


>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 323

 Score =  206 bits (504), Expect = 3e-52
 Identities = 100/192 (52%), Positives = 127/192 (66%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T N G  IP  G GTW++KP EV  AV+ A+  GYRHIDCA +Y NE EVG  I    K 
Sbjct: 8   TINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR---KS 64

Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
           GV  RE++FIT KLWNT H P+ V  AL +TL +L V YLDLYL+HWP A+K     FP 
Sbjct: 65  GV-PREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPL 123

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
           +  G    +++DY+ T++AME L+  G V++IGVSNFN ++LE LL   +V P VNQ+E 
Sbjct: 124 NDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEA 183

Query: 599 HPYLNQKRLKEF 634
           HPYL Q  L +F
Sbjct: 184 HPYLQQPDLLQF 195


>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
           Aldehyde reductase - Salinibacter ruber (strain DSM
           13855)
          Length = 321

 Score =  205 bits (501), Expect = 6e-52
 Identities = 95/193 (49%), Positives = 127/193 (65%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           ++F NG+ +P+ GLGTWKS PGEV +AV  A++ GYRH+DCA +Y NE EVG A++    
Sbjct: 4   ISFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFD 63

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
            G + R+D+++TSKLWN  H PD VR AL++TL +L +  LDLYLIHWP A + +   FP
Sbjct: 64  AGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVD-FP 122

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                 +    V   +TW AME L K+GLV+ IGVSNF+   L+ +L    V+P +NQVE
Sbjct: 123 ESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVE 182

Query: 596 CHPYLNQKRLKEF 634
            HPYL Q  L  F
Sbjct: 183 MHPYLPQPELVSF 195


>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
           tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 345

 Score =  202 bits (493), Expect = 6e-51
 Identities = 96/181 (53%), Positives = 124/181 (68%), Gaps = 2/181 (1%)
 Frame = +2

Query: 98  GTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK 277
           GT KS   +V  A K A+D+GYRH+D A++Y +E  VG+A   K  +G + REDLF TSK
Sbjct: 47  GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106

Query: 278 LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY 457
           LWNTFH+P LVR AL++TL  L + Y+DLYLIH P ++K    LFP ++ G   F   D 
Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166

Query: 458 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKE 631
           + TW+A+E     GLVKSIGVSNFN +QLE +L    +  KPV NQ+ECHPYLNQK++ E
Sbjct: 167 LQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLE 226

Query: 632 F 634
           F
Sbjct: 227 F 227


>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
           Arabidopsis thaliana|Rep: Uncharacterized protein
           At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 283

 Score =  198 bits (484), Expect = 7e-50
 Identities = 102/200 (51%), Positives = 126/200 (63%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MA  I     N G   P  GLGTW++ PG V  AV  A+ IGYRHIDCA +YGNEKE+G 
Sbjct: 1   MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
            +    ++ VV REDLFITSKLW T H P  V  AL  TL +L ++Y+DLYLIHWP   K
Sbjct: 61  VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
           + GS+    ++       VD   TWKAME L   G  ++IGVSNF++K+L  LL+ A V 
Sbjct: 121 K-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVP 175

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P VNQVECHP   Q +L+EF
Sbjct: 176 PAVNQVECHPSWRQTKLQEF 195


>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
           Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 315

 Score =  198 bits (484), Expect = 7e-50
 Identities = 102/200 (51%), Positives = 126/200 (63%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MA  I     N G   P  GLGTW++ PG V  AV  A+ IGYRHIDCA +YGNEKE+G 
Sbjct: 1   MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
            +    ++ VV REDLFITSKLW T H P  V  AL  TL +L ++Y+DLYLIHWP   K
Sbjct: 61  VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
           + GS+    ++       VD   TWKAME L   G  ++IGVSNF++K+L  LL+ A V 
Sbjct: 121 K-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVP 175

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P VNQVECHP   Q +L+EF
Sbjct: 176 PAVNQVECHPSWRQTKLQEF 195


>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
           Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
           posadasii
          Length = 314

 Score =  197 bits (481), Expect = 2e-49
 Identities = 93/200 (46%), Positives = 126/200 (63%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MA +      N GE IP  G GTW+ +  +   AV  A+  GYRHID A VYG EK +G 
Sbjct: 1   MASRHTTFRLNTGEDIPAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGR 59

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
           A+        ++R++LFITSKLWN  HRP+ V  A+ ++L NL + YLDLYL+HWP A+ 
Sbjct: 60  ALA----RSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFA 115

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
               +FP D  G  +  D+DYVDT+KAME LVK G  K+IG+SNF+  ++ERLL+  ++ 
Sbjct: 116 PGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIV 175

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P V Q+E HP+L Q    E+
Sbjct: 176 PAVMQMELHPWLQQNDFVEW 195


>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 321

 Score =  197 bits (480), Expect = 2e-49
 Identities = 100/196 (51%), Positives = 131/196 (66%), Gaps = 6/196 (3%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           N+G  IP  GLGT+ S+ PGEV  A+ +A+  GYRHID A  YGNEK +G ++    KEG
Sbjct: 20  NDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEG 79

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT- 418
            + RED+F TSKLWN+ H  +LV     +T+++L + YLDLYLIHWP A++    L  T 
Sbjct: 80  EIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTI 139

Query: 419 ----DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
               DQ+G    + V   +TW+ ME LV+ GLVKSIGVSNFN + L  LL +A +KPVVN
Sbjct: 140 EPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVN 199

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HPYL Q +L+E+
Sbjct: 200 QVEIHPYLTQFKLQEY 215


>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
           1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
           n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
           4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
           5-beta-reductase) - Homo sapiens (Human)
          Length = 326

 Score =  197 bits (480), Expect = 2e-49
 Identities = 100/199 (50%), Positives = 129/199 (64%), Gaps = 6/199 (3%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           +  ++G +IP+ GLGT+   KS P G    +VK AID GYRHID AY+Y NE EVGEAI 
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
            KI EG V RED+F   KLW T H P++VR  L+ TL  L + Y+DLY+I  P A+K   
Sbjct: 70  EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KP 577
            ++P D++GK  +   +   TW+AME     GLVKS+GVSNFN +QLE +L    +  KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189

Query: 578 VVNQVECHPYLNQKRLKEF 634
           V NQVECHPY  Q +L +F
Sbjct: 190 VSNQVECHPYFTQPKLLKF 208


>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
           Aldehyde reductase 1 - Sporobolomyces salmonicolor
          Length = 323

 Score =  196 bits (479), Expect = 3e-49
 Identities = 99/198 (50%), Positives = 129/198 (65%), Gaps = 5/198 (2%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           +   T N G ++ + G GTW++ PGEV Q VK AI+ GYRH+D A VY N+ EVG AI  
Sbjct: 2   VGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAI-- 59

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 403
             KE  V REDLFITSKLWN  HRP+ V  AL +TL  L ++YLDLYLIHWP A+  +G 
Sbjct: 60  --KEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGD 117

Query: 404 ---SLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571
              +LFP     +++   +V  VDTWKAM  L+  G VK+IGVSNF++K ++ +++   V
Sbjct: 118 ITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGV 177

Query: 572 KPVVNQVECHPYLNQKRL 625
            P VNQ+E HP L Q  L
Sbjct: 178 TPSVNQIERHPLLLQPEL 195


>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
           Schizosaccharomyces pombe|Rep: Probable oxidoreductase
           C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
          Length = 321

 Score =  196 bits (477), Expect = 5e-49
 Identities = 93/191 (48%), Positives = 124/191 (64%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T  +G  IP  GLGTW+S+P +   AVK A+  GYRHID A +YGNE EVG+ I    KE
Sbjct: 17  TLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGI----KE 72

Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
             V R+D+++TSKLW   H P+ V  AL++TL +L + YLD YLIHWP ++K     FP 
Sbjct: 73  SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPK 132

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
           D+ G + +      +TWKAME L++ G V+ IG+SNFN   LER+L+ A VKP V+Q+E 
Sbjct: 133 DKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMEL 192

Query: 599 HPYLNQKRLKE 631
           HP+L Q    E
Sbjct: 193 HPFLPQTEFVE 203


>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
           protein; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to LOC553452 protein -
           Strongylocentrotus purpuratus
          Length = 321

 Score =  194 bits (474), Expect = 1e-48
 Identities = 96/202 (47%), Positives = 128/202 (63%), Gaps = 2/202 (0%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MA     +    G  +P+ G GTW+ KP EV + ++ AID GYRHID A +YGNEK VG+
Sbjct: 1   MASSNTHIVLPGGRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGD 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
            I +KI +G + REDLF+TSKLW T   P  V  + +++L +L + YLDL+LIH P +  
Sbjct: 61  GIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAV 120

Query: 395 EDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571
                FP D +G     D +DYVDTW+ ME LV +GLV++IGVSNF   Q++R+L     
Sbjct: 121 GGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPK 180

Query: 572 KPVVN-QVECHPYLNQKRLKEF 634
            P+ N QVECHP+L Q  L EF
Sbjct: 181 YPIANVQVECHPFLAQNELIEF 202


>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 345

 Score =  194 bits (472), Expect = 2e-48
 Identities = 95/192 (49%), Positives = 127/192 (66%), Gaps = 2/192 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N G  +P  GLGTW+SK  EV  AV  A+  GYRHID A VYGNE+EVG+ +    +   
Sbjct: 10  NTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM----RLSG 65

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP--T 418
           V RE++F+TSKLWNT H P+ V  A+ ++L +L   YLDLYLIHWP A++   +      
Sbjct: 66  VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPVN 125

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
           +Q+G I   DV   DTW AME LV++G V+SIGVSNF  +++E LL+ A + P VNQ+E 
Sbjct: 126 EQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIEA 185

Query: 599 HPYLNQKRLKEF 634
           HP+L Q+ L E+
Sbjct: 186 HPFLQQRDLLEW 197


>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
           ATCC 50803
          Length = 313

 Score =  193 bits (471), Expect = 3e-48
 Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 4/179 (2%)
 Frame = +2

Query: 83  PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 256
           P  G GTW++ P  V  AV+ A+  GYRHIDCAYVY NE+ +G A     K+    + RE
Sbjct: 5   PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--GSLFPTDQSG 430
           D++ITSKLWN  HRP+LVR   ++T+ +L V YLDL+L+HWP A+  +  G LFP D  G
Sbjct: 65  DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607
           +     V   DTW+AME LV+EGLVK IGVSN+    L  LL +A +KP+VNQ+E HP+
Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPW 183


>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
           Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
           (Human)
          Length = 263

 Score =  191 bits (465), Expect = 1e-47
 Identities = 100/192 (52%), Positives = 123/192 (64%), Gaps = 21/192 (10%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           IP  GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG  I  KIKEG V RED
Sbjct: 4   IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63

Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL-- 409
           LFI +KLW T H+  LV  A +++L  L + YLDLYLIHWP  +K            L  
Sbjct: 64  LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123

Query: 410 ---------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
                     P D+S  +  SD D++DTW+AME LV  GLVK+IGVSNFN +QLERLL  
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183

Query: 563 ATV--KPVVNQV 592
             +  KP+ NQ+
Sbjct: 184 PGLRFKPLTNQI 195


>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
           family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 305

 Score =  190 bits (464), Expect = 2e-47
 Identities = 99/192 (51%), Positives = 125/192 (65%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T NNG  IP  GLGTW S  GEV +AV+ AI  GYRHIDCA  YGNEKEVG+ I S I +
Sbjct: 6   TLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAK 65

Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
           G V RE+LF+T+KLW+T    + VR A  E+L  L ++YLDLY+IH P        L   
Sbjct: 66  GYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIP--------LTAD 117

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
            ++G+     +   +TW+ ME LV+EGLVKSIGVSNFN K+LE LL  A ++P VNQ E 
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177

Query: 599 HPYLNQKRLKEF 634
           H Y  + +L +F
Sbjct: 178 HIYYQRPKLHQF 189


>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
           Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
           atlanticus HTCC2559
          Length = 316

 Score =  190 bits (463), Expect = 2e-47
 Identities = 90/191 (47%), Positives = 121/191 (63%)
 Frame = +2

Query: 62  FNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           F +G++IP  GLGTWKS P +V +AVK A++ GY+HIDCA  Y NE  VGEA     + G
Sbjct: 6   FRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESG 65

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
            V RED+F+TSKLWN  H+ + V  AL++TL +LN+ YLDLYL+HWP A+K   + FP  
Sbjct: 66  NVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFPEK 125

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
               +   +    +T  AM    K+GL+K +GVSNF+ ++LE L       P +NQVE H
Sbjct: 126 DEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVELH 185

Query: 602 PYLNQKRLKEF 634
           PYL Q  L  +
Sbjct: 186 PYLPQNDLYSY 196


>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
           Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
           sp. (strain CC9311)
          Length = 336

 Score =  189 bits (461), Expect = 4e-47
 Identities = 92/203 (45%), Positives = 129/203 (63%)
 Frame = +2

Query: 26  ISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205
           I  + P +   + +NG+ +P+ GLGT KS+  +V ++V++AI IGYRHIDCA +YGNE+E
Sbjct: 12  IKDVIPTMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEE 71

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
           VG+AI   I+   +TR +L+ITSKLW+  H  + V  AL ++L NL V YL+LYLIHWP 
Sbjct: 72  VGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPV 131

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
             + +   F       +   +    +TW+AME    +GL K IGVSNF  K+L++L+ H 
Sbjct: 132 GIRPE-KTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHC 190

Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634
             KP VNQVE HP L Q  L E+
Sbjct: 191 KQKPEVNQVEHHPLLQQPTLIEY 213


>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
           n=39; cellular organisms|Rep: NADPH-dependent aldose
           reductase GRE3 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 327

 Score =  184 bits (449), Expect = 1e-45
 Identities = 94/204 (46%), Positives = 128/204 (62%), Gaps = 10/204 (4%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           +VT NNG  +P+ GLG WK         + +AI +GYR  D A  YGNEKEVGE I   I
Sbjct: 4   LVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK--EDGS 406
            EG+V+R+D+F+ SKLWN FH PD V+ AL++TL ++ + YLDLY IH+P A+K      
Sbjct: 64  SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123

Query: 407 LFP--------TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
            +P         ++ G I  + V  +DT++A+E  V EGL+KSIGVSNF    ++ LL+ 
Sbjct: 124 KYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRG 183

Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634
             +KPV  Q+E HPYL Q+ L EF
Sbjct: 184 CRIKPVALQIEHHPYLTQEHLVEF 207


>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
           Ascomycota|Rep: Aldo/keto reductase family proteins -
           Aspergillus oryzae
          Length = 323

 Score =  184 bits (448), Expect = 2e-45
 Identities = 91/192 (47%), Positives = 123/192 (64%), Gaps = 2/192 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N+G  IP  GLGTW SKP EV  AV+ A+  GYRHID A  Y NE EVG       K+  
Sbjct: 10  NSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGW----KKSG 65

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE-DGSLFPTD 421
           V R+ +FITSKLWNT H P+ V  A+ +TL +L   YLDLYLIHWP A++  + +L P D
Sbjct: 66  VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPID 125

Query: 422 Q-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
             + + + ++V   DTW A+E LV+   ++SIG+SNF   +++ LL+ A + P VNQ+E 
Sbjct: 126 PVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIEA 185

Query: 599 HPYLNQKRLKEF 634
           HPYL Q  L ++
Sbjct: 186 HPYLQQPGLHKY 197


>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 337

 Score =  182 bits (444), Expect = 5e-45
 Identities = 94/202 (46%), Positives = 119/202 (58%), Gaps = 2/202 (0%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MAP   +V   NG  IP  GLGTWK++P EV  AV+DA+  GY H+DCA  Y NE EVGE
Sbjct: 1   MAPSTILVNDANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGE 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
           A+    + G   RED+F+TSKLWN   RP  VR AL  TL++L V YLDLYLIHWP A+K
Sbjct: 61  ALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWK 120

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ--HAT 568
             G++   D    I        + W  +E  V +GLV+ IGVSNFN  QL  L       
Sbjct: 121 R-GTVLQPDAEASI-------AECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTK 172

Query: 569 VKPVVNQVECHPYLNQKRLKEF 634
           ++P  NQ+E HP  +   L ++
Sbjct: 173 IQPACNQIESHPLWSNDSLVKY 194


>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
           cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
           cuniculi
          Length = 301

 Score =  182 bits (443), Expect = 6e-45
 Identities = 91/193 (47%), Positives = 119/193 (61%), Gaps = 3/193 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           NNG+ IP  GLGTW  +   V + A+++A+ +GYRHID A++YGNEK +G  +     EG
Sbjct: 9   NNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEG 68

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFP 415
           VV R+DLFITSKLWNTFH        L+ +L++L + Y+DLYLIHWP  +    DG++  
Sbjct: 69  VVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVES 126

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
             +  K      D V  WK ME LV  GL KSIG+SNF     E++L    + P   Q+E
Sbjct: 127 CGK--KYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIE 184

Query: 596 CHPYLNQKRLKEF 634
            HPYLNQK L EF
Sbjct: 185 LHPYLNQKELVEF 197


>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
           Aldose reductase - Magnaporthe grisea (Rice blast
           fungus) (Pyricularia grisea)
          Length = 312

 Score =  180 bits (437), Expect = 3e-44
 Identities = 94/196 (47%), Positives = 119/196 (60%), Gaps = 4/196 (2%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T N G  IP FGLGTW+   G + +AV  AI  GYR ID AYVYGNE+EVG+ I   I  
Sbjct: 7   TLNTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISS 66

Query: 239 GVVTREDLFITSKLWNTF-HRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 409
           G+V REDLF+ SK W T+  R +L    L ++L  L + Y+DLYL+HWP     +G+   
Sbjct: 67  GIVKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEK 123

Query: 410 FPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
           FP    G        ++VDTWK ME L   G  K++GVSN++   LE+LL HAT  P VN
Sbjct: 124 FPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVN 183

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HP L Q+ L +F
Sbjct: 184 QVENHPQLPQQELVDF 199


>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=3; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 309

 Score =  177 bits (430), Expect = 2e-43
 Identities = 90/193 (46%), Positives = 127/193 (65%), Gaps = 6/193 (3%)
 Frame = +2

Query: 74  ETIPVFGLGTWKSK-PGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           E IP  GLGT+ ++ P  +  AV  AI D GYRH+DCA  Y N++ +GEA++    +G V
Sbjct: 2   EVIPSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQV 61

Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFPTD 421
            RE+++ITSK+WNT HRPDL+   +++TL  L ++YLDL L+HW  A+  +ED    P D
Sbjct: 62  KREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRD 121

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVE 595
           ++GKI   ++D ++TWKAME     GL K IGVSNF+ +QLER+     VK  P  NQVE
Sbjct: 122 ETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVE 181

Query: 596 CHPYLNQKRLKEF 634
            H YL Q+ + ++
Sbjct: 182 SHMYLQQQPMLDY 194


>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
           family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 307

 Score =  176 bits (429), Expect = 3e-43
 Identities = 92/190 (48%), Positives = 124/190 (65%), Gaps = 1/190 (0%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE-AITSKIKEG 241
           NNG+ +P  GLGTW + PGEV +AV  A++ GYR IDCA  Y NEKE+GE  I   +K  
Sbjct: 9   NNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKNH 68

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
              RE+LF+TSKLW    +   +R +  E++ +L  +YLDLYLIHWP A K D S  P  
Sbjct: 69  --PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKP 124

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
           +     F D+D  + W+ ME LV EGLVKSIG+SNF   Q+E++++   +KPV+NQVE +
Sbjct: 125 ED----FLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELN 180

Query: 602 PYLNQKRLKE 631
            YL Q +L+E
Sbjct: 181 VYLQQNKLRE 190


>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein T08H10.1 - Caenorhabditis elegans
          Length = 333

 Score =  176 bits (429), Expect = 3e-43
 Identities = 84/193 (43%), Positives = 127/193 (65%), Gaps = 2/193 (1%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           +  N G  +P+FGLGTW+ K   E+T A++ A+D GYR ID A++Y NE  +G+ +   I
Sbjct: 6   IPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYI 65

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK-EDGSL 409
             G + RED+F+TSKL  T H P+ V   ++  L  L ++Y+DLYLIH P  +K ++GS 
Sbjct: 66  SSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSF 125

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
            P  ++G++  +++ ++DTW+A+E L KEG +K++GVSNF+  QL+ L   A VKP   Q
Sbjct: 126 APLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQQ 185

Query: 590 VECHPYLNQKRLK 628
           VECH Y  Q+ L+
Sbjct: 186 VECHIYWPQQELR 198


>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 339

 Score =  176 bits (428), Expect = 4e-43
 Identities = 81/203 (39%), Positives = 126/203 (62%), Gaps = 5/203 (2%)
 Frame = +2

Query: 41  PKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 220
           P    VT N+G  +PV G GTW+       + V+DA++ GYRHID A  + N++EV   I
Sbjct: 2   PIADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGI 61

Query: 221 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 400
               K   V RE+LF++SK+WNT+H  +     + E L+     Y+DL +IHWP  + ED
Sbjct: 62  KDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAED 121

Query: 401 -----GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
                  L+P   +GK+++SDVDY++TWKA+E   + G ++SIG++NFN  Q+E++    
Sbjct: 122 EPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTKG 181

Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634
            +KP V QVE +P+L+Q+ +++F
Sbjct: 182 LIKPAVLQVEMNPFLDQEEIRQF 204


>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
           Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  175 bits (427), Expect = 6e-43
 Identities = 84/169 (49%), Positives = 115/169 (68%), Gaps = 1/169 (0%)
 Frame = +2

Query: 131 QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLV 310
           +A + AI  GYRHID A+ Y NE +VG AI +KI++G++ R+D+FI SKLW T H P+ +
Sbjct: 4   RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63

Query: 311 RGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPL 487
                ++L +L + YLD YL+H+P   K+ G  LFP ++ GKI  +D+DYVD W+ ME L
Sbjct: 64  PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122

Query: 488 VKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
              G VKSIGVSNF  +Q++RLL  A + P VNQVE HPYL Q  L ++
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDY 171


>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
           Aldehyde reductase - gamma proteobacterium HTCC2207
          Length = 330

 Score =  175 bits (426), Expect = 7e-43
 Identities = 88/205 (42%), Positives = 132/205 (64%), Gaps = 9/205 (4%)
 Frame = +2

Query: 38  APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217
           A ++P V  ++ +++P  GLG WK       QAV +AI +GYRH+D A  YGNE++VGE 
Sbjct: 4   AIQVPGVKVSS-KSMPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEG 62

Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--Y 391
           I   I EG+ +RE+L+IT+KLWNT+HR + V  A + ++D+L + Y+DLYL+H+P A  Y
Sbjct: 63  IARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRY 122

Query: 392 KEDGSLFPT----DQSGKIQFSDVDYV---DTWKAMEPLVKEGLVKSIGVSNFNSKQLER 550
            +    +P     D S +    ++D V   +TW AME LV+ GLV+ IGV N+++  L  
Sbjct: 123 VDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHD 182

Query: 551 LLQHATVKPVVNQVECHPYLNQKRL 625
           L+ +A +KP + Q+E HPYL Q+ L
Sbjct: 183 LMSYARIKPAMLQIESHPYLTQEAL 207


>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
           CG2767-PA - Drosophila melanogaster (Fruit fly)
          Length = 329

 Score =  175 bits (426), Expect = 7e-43
 Identities = 86/196 (43%), Positives = 127/196 (64%), Gaps = 3/196 (1%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +TFNNGE +PV G+GTW++   E+  A+  A++ GYRHID A VYGNEK +G  +   + 
Sbjct: 7   LTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDGSL 409
            G V RE+LFI +K+    +RP  V   ++++L++L + Y+DLYL+H P      EDGS 
Sbjct: 67  AGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGS- 125

Query: 410 FPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
           F  D+ G ++     ++   W AME LV++GL KSIGVSNF+  Q+ RLL++  ++P  N
Sbjct: 126 FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANN 185

Query: 587 QVECHPYLNQKRLKEF 634
           Q+E H YL Q+ L +F
Sbjct: 186 QIEHHVYLQQRDLVDF 201


>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
           precursor; n=1; Spodoptera littoralis|Rep:
           3-dehydroecdysone 3beta-reductase precursor - Spodoptera
           littoralis (Egyptian cotton leafworm)
          Length = 345

 Score =  174 bits (424), Expect = 1e-42
 Identities = 89/202 (44%), Positives = 123/202 (60%), Gaps = 9/202 (4%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTW---------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNE 199
           +P++   N   +P   LGT+          SK  ++   V  AID+GYRH D A +Y  E
Sbjct: 22  VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81

Query: 200 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 379
            EVGEAI  KI EGV+ RED+F+T+KLWNT H+ + V  A++ETL+   + Y+DL+L+HW
Sbjct: 82  AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141

Query: 380 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 559
           P A  ED S            S+ DY++TW+A E +VK G  KSIG+SNFN  Q+  +LQ
Sbjct: 142 PIALNEDYS-----------HSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQ 190

Query: 560 HATVKPVVNQVECHPYLNQKRL 625
             T+KPV  Q+E HP + Q+ L
Sbjct: 191 ECTIKPVALQIEVHPQIIQEDL 212


>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
           melanogaster|Rep: CG40064-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 361

 Score =  174 bits (424), Expect = 1e-42
 Identities = 84/173 (48%), Positives = 122/173 (70%), Gaps = 2/173 (1%)
 Frame = +2

Query: 122 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRP 301
           + + AV  AI+ G+RH D AY Y NEKE+GEA+ ++IK G ++RE++F+T+KLWNT H P
Sbjct: 45  QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104

Query: 302 DLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKA 475
             VR   ++ L+ L   Y+DLYL+H+P  YK   D  L P     ++Q  ++DY+DTW+A
Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPM-SGDELQTVEIDYLDTWRA 163

Query: 476 MEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
           ME LVK G+V+SIG+SNFN +Q++R++Q ++ KPVVNQVE  P   QK L ++
Sbjct: 164 MENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDY 216


>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
           dehydrogenases of different specificities; n=4;
           Pezizomycotina|Rep: Similarity: shows similarity to
           several dehydrogenases of different specificities -
           Aspergillus niger
          Length = 381

 Score =  173 bits (422), Expect = 2e-42
 Identities = 89/200 (44%), Positives = 117/200 (58%), Gaps = 7/200 (3%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           VT N+G  IP  G GTW+S PG+V  AV +A+  GYRH+D A +Y N++EV E I    K
Sbjct: 7   VTLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYK 66

Query: 236 EGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
           +   + RED+FITSKLWN+ H P +V  AL E L  L + YLDLYL+HWP ++     LF
Sbjct: 67  DVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELF 126

Query: 413 PTDQSGKIQFSDV------DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
           P  +   ++  DV        VDTWKAM  L K    +++GVSN     LE ++    V 
Sbjct: 127 PLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAIINATGVV 185

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P VNQ+E HP L    L E+
Sbjct: 186 PAVNQIERHPVLQSNELIEY 205


>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 303

 Score =  172 bits (419), Expect = 5e-42
 Identities = 85/196 (43%), Positives = 128/196 (65%), Gaps = 2/196 (1%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           ++  NNG +IP  GLGT+K    +   A+K A++ GYR ID A+VY NE+ VG+A+    
Sbjct: 1   MLALNNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIF 60

Query: 233 KEGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
            +G  + RED+FI SKL  TFHRP+ V    + +L+ L + Y+DLYL+H P A ++ G  
Sbjct: 61  SQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSG-- 118

Query: 410 FPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
              D + + +  D V  ++TWKA+E   ++GLV+SIGVSNFN +QL  ++ H +++PVVN
Sbjct: 119 ---DGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVN 175

Query: 587 QVECHPYLNQKRLKEF 634
           QVEC    +Q +L++F
Sbjct: 176 QVECSIGFHQVKLRKF 191


>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=9; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 308

 Score =  171 bits (417), Expect = 9e-42
 Identities = 96/195 (49%), Positives = 124/195 (63%), Gaps = 10/195 (5%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           IP  GLGTWKS   E     +T A+K+A   GY HIDCA  Y NE  VG+A+      G+
Sbjct: 4   IPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSGI 60

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE---DGSLFP 415
             RE+++ITSKLWNT HR ++V  A ++TL +L + YLDLYL+H+P A++     GSL P
Sbjct: 61  -KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNP 119

Query: 416 TDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQHATVKPVVNQ 589
            D+ G   F D V  +DTWKAME LV++GLVK IGVSN+   QLERL    A   P  NQ
Sbjct: 120 LDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQ 179

Query: 590 VECHPYLNQKRLKEF 634
           VE + Y+ Q  L+E+
Sbjct: 180 VEFNLYMQQGPLREY 194


>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 700

 Score =  171 bits (416), Expect = 1e-41
 Identities = 86/198 (43%), Positives = 126/198 (63%), Gaps = 6/198 (3%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T  NG  IP  G GTWK    + T AV  AI  GYRHIDCA+ Y NE    +A+ + IK+
Sbjct: 13  TLANGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKK 68

Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY-KEDGSLFP 415
             V R  L++TSKLWN+FH P+ V  AL  +L +L   YLDLYL+HWP A+    GS+ P
Sbjct: 69  AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVP 128

Query: 416 TDQS---GKIQFSDV--DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580
           + +S     ++  D+  D++ T++ ME +VK+G V++IGVSNFN ++   ++  A++KPV
Sbjct: 129 SIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPV 188

Query: 581 VNQVECHPYLNQKRLKEF 634
           VNQVE +  ++ + L+ +
Sbjct: 189 VNQVEVNLGVHNEELRNY 206


>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG03517.1 - Gibberella zeae PH-1
          Length = 364

 Score =  170 bits (413), Expect = 3e-41
 Identities = 86/194 (44%), Positives = 126/194 (64%), Gaps = 3/194 (1%)
 Frame = +2

Query: 62  FNNGET---IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           FN  ET   IP FGLGTW +  G V  AV+ A+  GYRHID A ++ NE EVG+ I    
Sbjct: 51  FNKNETVRDIPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGI---- 106

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
           K   V+R+++++T KLWNT HRP+LVR A++ ++ NL V+YLDLYLIH+P A+       
Sbjct: 107 KASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAW------- 159

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
              ++  +  ++   +DTWKAME LV+ GL ++IG SNF  K + ++L+ A+++P  ++ 
Sbjct: 160 -VPETRDVD-NNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEF 217

Query: 593 ECHPYLNQKRLKEF 634
           E HPYL Q+   +F
Sbjct: 218 ETHPYLQQQSFVDF 231


>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 301

 Score =  169 bits (411), Expect = 5e-41
 Identities = 94/212 (44%), Positives = 125/212 (58%), Gaps = 22/212 (10%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           ++G  +P  GLGTW SKP EV  AV+ A+ +GYRHID A  Y NE EVG       K+  
Sbjct: 10  SSGYDMPAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNG----WKKSG 65

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYL------------------ 370
           V R+ +FITSKLWNT H PD V  A+ +TL +L   YLDLYL                  
Sbjct: 66  VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLTN 125

Query: 371 --IHWPQAYKE-DGSLFPTDQ-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSK 538
             IHWP A++  + +L P D  S + + +++   DTW A+E LV  G V+SIGVSNF  +
Sbjct: 126 NKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIE 185

Query: 539 QLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
           ++E LL+ A + P VNQ+E HPYL Q  L ++
Sbjct: 186 KIEELLKTARIPPAVNQIEAHPYLQQPALHKY 217


>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
           Aldehyde reductase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 313

 Score =  169 bits (410), Expect = 6e-41
 Identities = 81/186 (43%), Positives = 115/186 (61%), Gaps = 1/186 (0%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           IP  G GT  + P     A +DA+  G+RH DCA  Y NE+EVGEA+ +    G + RE+
Sbjct: 20  IPALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREE 79

Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439
           +F+T+KLWNT HRP+ V  A + +LD L + YLDLYLIH P A++      P DQ+G + 
Sbjct: 80  IFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVI 139

Query: 440 FSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616
           + + V   +TW A+E LV  G  ++IG+S+ +  +L  + + A +KP V QVE HPYL +
Sbjct: 140 YDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPE 199

Query: 617 KRLKEF 634
             L EF
Sbjct: 200 TELLEF 205


>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
           Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
          Length = 321

 Score =  169 bits (410), Expect = 6e-41
 Identities = 92/205 (44%), Positives = 129/205 (62%), Gaps = 5/205 (2%)
 Frame = +2

Query: 35  MAPKIPVVTFNNG-ETIPVFGLGTWKSKPGE---VTQAVKDAIDIGYRHIDCAYVYGNEK 202
           MA  IP V  ++G   +PV GLGT    P +   V +AV +A+ +GYRH D A +Y +E+
Sbjct: 1   MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQ 60

Query: 203 EVGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 379
            +G+AI   + EG++ +R++LFITSKLW +    + V  ALQ+TL NL ++Y+D+YLIHW
Sbjct: 61  PLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHW 120

Query: 380 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 559
           P + K     +P     K  F  +DY   W+AME   K GL K+IGVSNF+ K+L  +L 
Sbjct: 121 PVSSKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLA 177

Query: 560 HATVKPVVNQVECHPYLNQKRLKEF 634
           +A V P VNQVE +P   QK+L EF
Sbjct: 178 NAKVPPAVNQVEVNPCWQQKQLTEF 202


>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
           Trichoderma atroviride (Hypocrea atroviridis)
          Length = 327

 Score =  169 bits (410), Expect = 6e-41
 Identities = 86/199 (43%), Positives = 123/199 (61%), Gaps = 7/199 (3%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           T N G  IP  G GT+ ++   GE   AV  A+D+GYRH+DCA+ Y NE EVG+AI   +
Sbjct: 16  TLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFL 75

Query: 233 -KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS- 406
            +   VTR+DLFI +K+WN  H P+ V+ + + + +NL V Y+DL+L+HWP A +++   
Sbjct: 76  ARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADR 135

Query: 407 LFPTDQSGKIQFSDV---DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577
                  GK   +     +   TW+AME LV  G+VK+IGVSN+    L++LL+ A +KP
Sbjct: 136 TVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKP 195

Query: 578 VVNQVECHPYLNQKRLKEF 634
            VNQ+E HP+L    L EF
Sbjct: 196 AVNQIEIHPFLPNTELVEF 214


>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
           eudicotyledons|Rep: Chalcone reductase - Sesbania
           rostrata
          Length = 322

 Score =  168 bits (409), Expect = 8e-41
 Identities = 89/201 (44%), Positives = 124/201 (61%), Gaps = 4/201 (1%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGTW-KSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           KIP V  N+G  +PV G+GT  +S+P    +     DAI +GYRH D A VYG E+ +G 
Sbjct: 5   KIPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGM 64

Query: 215 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391
           A++  I++G++ +R+++FITSK WNT    DL+  AL+ TL  L ++Y+DLYLIHWP   
Sbjct: 65  AVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRL 124

Query: 392 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571
           + D  L       K      D   TWKAME   + GL KSIG+ N+ +K+L +LL+ AT+
Sbjct: 125 RHD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATI 182

Query: 572 KPVVNQVECHPYLNQKRLKEF 634
            P VNQVE +P   Q  L+EF
Sbjct: 183 PPAVNQVEMNPSWQQGNLREF 203


>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
           Yarrowia lipolytica chromosome B of strain CLIB122 of
           Yarrowia lipolytica - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 337

 Score =  168 bits (409), Expect = 8e-41
 Identities = 92/196 (46%), Positives = 119/196 (60%), Gaps = 4/196 (2%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           T NNG+TIP  GLGTWKS   EV  AV+ A+ + GYRHID A+ Y NE  VG  I   ++
Sbjct: 35  TLNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRAME 94

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 409
           +GV  RED+F+T+K+W T+H  D V   L  +L+ L + Y+D+ LIHWP     +G+  +
Sbjct: 95  KGV-KREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLNPNGNDPV 151

Query: 410 FPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
           +P    G     +      TWK ME ++K G  KSIGVSNF+   LE LL+ A V P VN
Sbjct: 152 YPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEVVPAVN 211

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HP L Q  L EF
Sbjct: 212 QVELHPLLPQLELMEF 227


>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
           reductase; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to aldose reductase -
           Strongylocentrotus purpuratus
          Length = 274

 Score =  167 bits (406), Expect = 2e-40
 Identities = 88/177 (49%), Positives = 108/177 (61%)
 Frame = +2

Query: 104 WKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW 283
           W SKPG+V  AVK AID GYRHIDCA+VYGNE EVG  +  K    VV RED+FITSKLW
Sbjct: 5   WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64

Query: 284 NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVD 463
           N  H PD V  A   TL NL + Y+DLYL+HWP AY                        
Sbjct: 65  NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAY------------------------ 100

Query: 464 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
             +AME LV  G  K+IG+SNF+ K ++R+++ AT++P   QVE HP L Q++L EF
Sbjct: 101 --QAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEF 155


>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
           reductase family 1, member B10, partial; n=1; Macaca
           mulatta|Rep: PREDICTED: similar to aldo-keto reductase
           family 1, member B10, partial - Macaca mulatta
          Length = 275

 Score =  167 bits (406), Expect = 2e-40
 Identities = 96/184 (52%), Positives = 115/184 (62%), Gaps = 8/184 (4%)
 Frame = +2

Query: 107 KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK--- 277
           KS  G+V +AVK AID GYRHIDCAYVY NE EVGEAI  KI+E  V REDLFI SK   
Sbjct: 42  KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101

Query: 278 ---LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD 448
              LW TF    LVR A ++TL +L + YLD+YLIHWPQ +K                  
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------------------ 143

Query: 449 VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKR 622
                   AME LV EGLVK++G+SNFN  Q+E+LL    +  KPV NQVECHPYL Q++
Sbjct: 144 --------AMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK 195

Query: 623 LKEF 634
           L ++
Sbjct: 196 LIQY 199


>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=10; Trichomonas vaginalis|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 312

 Score =  167 bits (406), Expect = 2e-40
 Identities = 84/191 (43%), Positives = 120/191 (62%), Gaps = 6/191 (3%)
 Frame = +2

Query: 80  IPVFGLGTWKSK-PGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 253
           IP  G GT+ +  P ++  A+  AI+  G RHID A+ Y N+  +GE +     +G + R
Sbjct: 3   IPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKR 62

Query: 254 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK----EDGSLFPTD 421
           ED+FIT+KLW T HR DLV   L E L  L + Y+DL+LIH P A+K    +DG++ P D
Sbjct: 63  EDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKD 122

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
           + GKIQ+  +D ++T+ AME   K+GL + IGVSNF+ +QLER+  +  +KP  NQVEC+
Sbjct: 123 EKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVECN 182

Query: 602 PYLNQKRLKEF 634
            Y   K L  +
Sbjct: 183 IYRQFKPLLSY 193


>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
           Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
           Trichoplusia ni (Cabbage looper)
          Length = 308

 Score =  167 bits (405), Expect = 3e-40
 Identities = 93/206 (45%), Positives = 123/206 (59%), Gaps = 1/206 (0%)
 Frame = +2

Query: 11  AAAKIISKMAPKIPVVTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYV 187
           A    IS    K P+   N+G  IP   LGT+      +V QAV  AI  GYRHID A +
Sbjct: 12  ALVNAISGEPGKAPLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAAL 71

Query: 188 YGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 367
           YGNE+EVG+ I   I++G+V RE+LF+T+KLWN  H    V  AL+E+L  L + Y+DLY
Sbjct: 72  YGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLY 131

Query: 368 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 547
           LIH P+A  E+G   P          D+D ++TW  ME   K GL KSIGVSNF++  L+
Sbjct: 132 LIHSPEATNENGD--PV---------DIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLD 180

Query: 548 RLLQHATVKPVVNQVECHPYLNQKRL 625
           RL+  +   P VNQ+E HP   Q++L
Sbjct: 181 RLIAGSNTVPAVNQIEVHPSKTQEKL 206


>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 293

 Score =  166 bits (403), Expect = 4e-40
 Identities = 91/197 (46%), Positives = 116/197 (58%), Gaps = 1/197 (0%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           IP +  NNG  IP  GLG ++    E T+ A+K A+  GYRHID A  YGNE+ VGEAI 
Sbjct: 11  IPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEAI- 69

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
              +E  V R+ +F+TSKLWN+    D  + A QETLD L + YLDLYLIHWP       
Sbjct: 70  ---RESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAP----- 121

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
                            Y+D+W+AME L K G +K+IGVSNFN  Q+  +L H TVKPVV
Sbjct: 122 ----------------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVV 165

Query: 584 NQVECHPYLNQKRLKEF 634
           +Q+E HPY  Q  +  +
Sbjct: 166 DQIETHPYFQQNDMHAY 182


>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
           Lactobacillus reuteri 100-23
          Length = 288

 Score =  165 bits (402), Expect = 6e-40
 Identities = 87/180 (48%), Positives = 112/180 (62%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NNG  IP  G GT+++      QAVK+AI+ GYRHID A VYGNE+ VG+ I    K+  
Sbjct: 14  NNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGI----KDSG 69

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + REDLF+TSKLWNT    +  + A QETLD L + YLDLYLIHWP   K+ G     D 
Sbjct: 70  IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG-----DD 124

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
           + KI        +TW+AME L  EG +++IGVSNF    +  L++ A V P V+Q+E HP
Sbjct: 125 AAKIN------AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHP 178


>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_22, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 360

 Score =  165 bits (402), Expect = 6e-40
 Identities = 84/191 (43%), Positives = 118/191 (61%), Gaps = 1/191 (0%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N    IP  GLGTW+S      +AVK A+  GYR IDCA++YGNE EVGEA+      G 
Sbjct: 15  NTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAFN-GS 73

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + RED+F+TSKL+ T +  + +  +++ +L NL V YLDLYL+HWP       +  P   
Sbjct: 74  LKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSN 133

Query: 425 SGKIQFSDVDYVD-TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
           SG      ++ +   WKAME L++ GLV++IGVSNF  +Q++ LL+ A + P VNQV+ H
Sbjct: 134 SGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLH 193

Query: 602 PYLNQKRLKEF 634
           P+  Q  L +F
Sbjct: 194 PFWRQDELVKF 204


>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
           Dikarya|Rep: Aldo-keto reductase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 353

 Score =  165 bits (400), Expect = 1e-39
 Identities = 87/193 (45%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N G +IP  GLGTW++K GEV QAV  A+  GYRHID A  Y NE EVG      IK+  
Sbjct: 42  NTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLG----IKDSG 97

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--LFPT 418
           V R ++F+TSK+W+++H  D V   L  TL +L   YLDLYLIHWP     +G+  LFP 
Sbjct: 98  VPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPVRLAPNGTHPLFPV 155

Query: 419 DQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
              G      D D   TW  ME ++K+G  K+IG+SN     +E +++   V P VNQVE
Sbjct: 156 KPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGKVTPAVNQVE 215

Query: 596 CHPYLNQKRLKEF 634
            HPY  Q  L ++
Sbjct: 216 LHPYCPQHALLKY 228


>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
           synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
           6'-deoxychalcone synthase - Glycine max (Soybean)
          Length = 315

 Score =  164 bits (398), Expect = 2e-39
 Identities = 87/204 (42%), Positives = 129/204 (63%), Gaps = 5/204 (2%)
 Frame = +2

Query: 38  APKIPVVTFNNG---ETIPVFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEK 202
           A +IP + F N    + +PV G+G+    +   +  +A+ +A+  GYRH D A  YG+E+
Sbjct: 4   AIEIPTIVFPNSSAQQRMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQ 63

Query: 203 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382
            +GEA+   I  G+V+R+DLF+TSKLW T + P LV  AL+++L  L ++YLDLYLIHWP
Sbjct: 64  ALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWP 123

Query: 383 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
            + +     FP +    + F   D    W++ME   K GL K+IGVSNF+ K+L+ LL  
Sbjct: 124 LSSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSV 180

Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634
           AT++PVV+QVE +    QK+L+EF
Sbjct: 181 ATIRPVVDQVEMNLAWQQKKLREF 204


>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA15457-PA - Nasonia vitripennis
          Length = 388

 Score =  162 bits (394), Expect = 5e-39
 Identities = 87/200 (43%), Positives = 120/200 (60%), Gaps = 1/200 (0%)
 Frame = +2

Query: 38  APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217
           A  +  +  ++G  IP  GLGT   K  E+  A+  A++ GYRHID A+ Y NE  +G+ 
Sbjct: 20  AQAVEKLKLSSGHEIPAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKI 79

Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397
           +     +G   RED+FITSKL +  +RP  V   L+ +L +L + Y+D+YLIH P A KE
Sbjct: 80  LKKWFDKGG-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKE 138

Query: 398 DGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
             +L    D+ G   F DVD+   WKAME  VKEG  KSIG+SNFN  Q+  +  +A +K
Sbjct: 139 GENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIK 198

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P   QVE H YL QK+L++F
Sbjct: 199 PSNLQVETHAYLQQKQLRKF 218


>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 268

 Score =  162 bits (394), Expect = 5e-39
 Identities = 85/190 (44%), Positives = 117/190 (61%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           +NG TIP+ G GT+     +V  A+K A+D GYRH+DCA++YGNE  VGEA    IK   
Sbjct: 7   SNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEA----IKASG 62

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + R DLFITSK+WN     D    A  +TL +L + YLDLYLIHWP   ++D  L     
Sbjct: 63  IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWPN--EDDFEL----- 115

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
                      +DTW+ +E L ++  V++IGVSNF+  QL+++ + ATVKP++NQ+E HP
Sbjct: 116 ----------TLDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHP 165

Query: 605 YLNQKRLKEF 634
           Y  Q  L +F
Sbjct: 166 YKVQADLGQF 175


>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
           Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 316

 Score =  162 bits (394), Expect = 5e-39
 Identities = 78/193 (40%), Positives = 118/193 (61%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +TF NG T+P  G GTW++   EV +A+ +A++ GYRHID A VY NEK +G+ +   + 
Sbjct: 7   ITFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
            G VTR++LFI +KL     R   V   L+ +LD+L ++Y+DLY +H P    E    F 
Sbjct: 67  AGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFL 126

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
            +    +  +  D+V  WKAME + + GL ++IG+SNFN +Q++R+L +  +KP   Q+E
Sbjct: 127 VEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIE 186

Query: 596 CHPYLNQKRLKEF 634
            H YL Q  L +F
Sbjct: 187 NHIYLQQPELVKF 199


>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
           Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
           - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
           NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
           DSM 3700 / NRRL 181))
          Length = 321

 Score =  162 bits (394), Expect = 5e-39
 Identities = 81/197 (41%), Positives = 117/197 (59%), Gaps = 5/197 (2%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P    N+G  +P+ G G WK         +  AI  GYR  D A  YGNE E G+ +   
Sbjct: 4   PSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARA 63

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDG 403
           I+EG+V REDLFI SKLWN+FH  D V    ++ L +  + Y DL+++H+P A  Y +  
Sbjct: 64  IQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVDPA 123

Query: 404 SLFP---TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
             +P     ++ K++FS+    +TW AME LV + L +SIGVSNF+++ L  LL++A ++
Sbjct: 124 VRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYARIR 183

Query: 575 PVVNQVECHPYLNQKRL 625
           P   Q+E HPYL Q+RL
Sbjct: 184 PATLQIEHHPYLTQERL 200


>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
           Kineococcus radiotolerans SRS30216
          Length = 289

 Score =  161 bits (392), Expect = 1e-38
 Identities = 85/200 (42%), Positives = 117/200 (58%)
 Frame = +2

Query: 29  SKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 208
           S  A  +P +  N+G  IP  G G ++ +PG+  QAVK A+D+GYRHID A +YGNE EV
Sbjct: 6   SVSAMTVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEV 65

Query: 209 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388
            + I     +  V R+++++TSKL N FH PD  R A+ ++++ L    +DLYLIHWP  
Sbjct: 66  AQGIA----DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLIHWP-- 118

Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
                   PT   G       D+V TWK +E     G ++SIGVSNF    L+RL Q AT
Sbjct: 119 -------LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEAT 164

Query: 569 VKPVVNQVECHPYLNQKRLK 628
           V P VNQ+E HPY   + ++
Sbjct: 165 VVPAVNQIEVHPYFGNEEVR 184


>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
           eudicotyledons|Rep: Aldose reductase-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 316

 Score =  160 bits (388), Expect = 3e-38
 Identities = 85/189 (44%), Positives = 119/189 (62%), Gaps = 2/189 (1%)
 Frame = +2

Query: 71  GETIPVFGLGTW-KSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           GETIP+ G+GT+   K  E T  AV  AI IGYRH D A +YG+E+ +G A+   I  G 
Sbjct: 11  GETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGT 70

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           V R+DLF+TSKLW++ H   +   AL +TL  + + YLD YL+HWP   K  G   P  +
Sbjct: 71  VQRDDLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLK-PGVSEPIPK 127

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
             + +  D+   +TW+ ME  ++ GL +SIGVSNF+SK++  LL  A+V P VNQVE HP
Sbjct: 128 EDEFE-KDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHP 186

Query: 605 YLNQKRLKE 631
              Q++L++
Sbjct: 187 LWRQRKLRK 195


>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
           GCY protein - Lodderomyces elongisporus (Yeast)
           (Saccharomyces elongisporus)
          Length = 295

 Score =  160 bits (388), Expect = 3e-38
 Identities = 86/206 (41%), Positives = 123/206 (59%), Gaps = 4/206 (1%)
 Frame = +2

Query: 29  SKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKE 205
           S+++      T NNG  IP  GLGTW +   +   +A   A+  GY+HID A  YGNE +
Sbjct: 3   SQLSINTKTYTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQ 62

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
           VG AI     +  V+R+++F+T+KLWN  H+     GAL E+L  L ++Y+DLYLIHWP 
Sbjct: 63  VGRAIA----DSGVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWP- 115

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG-LVKSIGVSNFNSKQLERLL-- 556
                      D   +  + D D+VDTW+ ++ + KEG  VK+IGVSNFN K+L++LL  
Sbjct: 116 --------LSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNS 167

Query: 557 QHATVKPVVNQVECHPYLNQKRLKEF 634
           +   V PV+NQ+E HP L Q  L ++
Sbjct: 168 EGVNVVPVINQIEAHPLLTQPDLFDY 193


>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
           organisms|Rep: Probable reductase - Leishmania major
          Length = 284

 Score =  159 bits (386), Expect = 5e-38
 Identities = 91/195 (46%), Positives = 119/195 (61%), Gaps = 1/195 (0%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           +VT +NG  +P FGLG W+S  GEVT+ AV  A+  GYRHID A +Y NE+ VG  +   
Sbjct: 8   MVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGL--- 64

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
            +   V RED+FIT+KLWNT    +    A +E+   L V Y+DLYLIHWP+  K+  S 
Sbjct: 65  -RASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG-KDILS- 121

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
               + GK       Y+D+W+A E L KE  V++IGVSNF+   LE +L   TV P+VNQ
Sbjct: 122 ----KEGK------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQ 171

Query: 590 VECHPYLNQKRLKEF 634
           VE HP  NQ  L+ F
Sbjct: 172 VELHPLNNQADLRAF 186


>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
           chain; n=3; Saccharomycetaceae|Rep: D-arabinose
           dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 344

 Score =  159 bits (385), Expect = 7e-38
 Identities = 97/228 (42%), Positives = 133/228 (58%), Gaps = 17/228 (7%)
 Frame = +2

Query: 2   SSQAAAKIISKMA-PKIPVVTF--NNGETIPVFGLGTWK--SKPGEVTQAVKDAIDIGYR 166
           S  +   I+  M  PK   + F  NNG  IP  GLGT     K  E  QAVK AI  GYR
Sbjct: 4   SVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYR 63

Query: 167 HIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLN 346
           HID A+ Y  E  VGEAI   +++G + REDLFIT+K+W      D V  +L E+L  L 
Sbjct: 64  HIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALG 121

Query: 347 VQYLDLYLIHWPQAYKE-------DGSL-FPTDQSGKIQF-SDVDYVDTWKAMEPLV--- 490
           ++Y+DL L HWP  +++        G +  P D SGK  + +D DY++T+K +E +    
Sbjct: 122 LEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDP 181

Query: 491 KEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
            +  V++IGVSNF+ + LERL++   VKP VNQVE HP+L Q  L++F
Sbjct: 182 NDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKF 229


>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
           Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
           sativa (Rice)
          Length = 323

 Score =  157 bits (382), Expect = 2e-37
 Identities = 79/192 (41%), Positives = 118/192 (61%), Gaps = 4/192 (2%)
 Frame = +2

Query: 71  GETIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           G  +P  G+GT  S    P     A   A+++G+RH D A +YG E  +GEAI    + G
Sbjct: 14  GRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEAIAEATRRG 73

Query: 242 VV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
           +V +RE++F+T+KLW T   P LV  +L+E+L NL ++Y+DLYL+HWP + K    + P 
Sbjct: 74  LVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLPV 133

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
            +   + F   D+   W+AME   + GL K+IGVSNF +K L++LL  AT+ P VNQVE 
Sbjct: 134 KREDAVPF---DFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVEM 190

Query: 599 HPYLNQKRLKEF 634
           +P   Q+ ++E+
Sbjct: 191 NPVWQQRTVREY 202


>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
           SCB49|Rep: ARA1 - unidentified eubacterium SCB49
          Length = 280

 Score =  157 bits (381), Expect = 2e-37
 Identities = 86/186 (46%), Positives = 113/186 (60%), Gaps = 2/186 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           NN   IP  G GTW++  G+    A+K AID GY+HID A +Y NEK VG  I    KE 
Sbjct: 8   NNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI----KEA 63

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
            + R+DLF+TSK+WN     +    A   T+++L + YLDLYLIHWP A  +        
Sbjct: 64  NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ-------F 116

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
           ++ K Q ++    DTW AME L K+G +K++GVSNF    L  LLQHAT+KP VNQ+E H
Sbjct: 117 ENWK-QLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYH 171

Query: 602 P-YLNQ 616
           P Y+ Q
Sbjct: 172 PGYMQQ 177


>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
           dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
           D-sorbitol-6-phosphate dehydrogenase - Malus domestica
           (Apple) (Malus sylvestris)
          Length = 310

 Score =  157 bits (381), Expect = 2e-37
 Identities = 79/197 (40%), Positives = 116/197 (58%), Gaps = 4/197 (2%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           VT ++G  +PV GLG W+ +  E+ + + +AI IGYRH DCA  Y +E +VGEA+    K
Sbjct: 4   VTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
            G+V RE+LFIT+K+WN+ H    V  A + +L+ L + YLDLYL+H+P   K +     
Sbjct: 64  TGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKT 121

Query: 416 TDQSGKIQFSDVDYV----DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
               G+ +  D+D       TW+ ME  V  GLV+SIG+SN+        L ++ +KP V
Sbjct: 122 ASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAV 181

Query: 584 NQVECHPYLNQKRLKEF 634
           +Q E HPY  +  L +F
Sbjct: 182 SQFETHPYFQRDSLVKF 198


>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
           reductase - Hordeum vulgare (Barley)
          Length = 320

 Score =  157 bits (380), Expect = 3e-37
 Identities = 81/180 (45%), Positives = 114/180 (63%), Gaps = 1/180 (0%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           +G  +P  GLGTW++   +   +V+ AI + GYRH+D A  YG EKEVG+ + + ++ G+
Sbjct: 20  SGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAGI 78

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
             R+DLF+TSK+W T   P+ VR AL+ TL +L + Y+DLY IHWP   K DG+  P + 
Sbjct: 79  -DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPPEA 136

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
              ++F   D    WK ME LVK+GLVK IGV N+   +L RLL+ A + P V Q+E HP
Sbjct: 137 GEVLEF---DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHP 193


>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Photorhabdus luminescens subsp. laumondii
          Length = 292

 Score =  156 bits (378), Expect = 5e-37
 Identities = 81/192 (42%), Positives = 114/192 (59%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P++   +G  +P  GLG+W S   ++ + +  A+DIGYR ID A +Y NEK VG A    
Sbjct: 5   PIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA---- 60

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           ++E  + RED+F+T+KLWN  H     R AL E+L+ L + Y+DLYLIHWP         
Sbjct: 61  LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWPAP------- 111

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
            P DQ          YV  W+ +  L KEGL++SIGVSNF  + ++RL+    V PV+NQ
Sbjct: 112 -PQDQ----------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQ 160

Query: 590 VECHPYLNQKRL 625
           +E HP L Q++L
Sbjct: 161 IELHPLLQQRQL 172


>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
           Benzil reductase - Bacillus subtilis
          Length = 276

 Score =  155 bits (375), Expect = 1e-36
 Identities = 89/194 (45%), Positives = 118/194 (60%), Gaps = 1/194 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           V  +NG  +P FGLG +K + G E T++VK AI  GYR ID A +Y NE+ VG  I    
Sbjct: 9   VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI---- 64

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
           KE  V RE+LFITSK+WN     +    A +++L+ L + YLDLYLIHWP          
Sbjct: 65  KESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------- 114

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                GK +     Y DTW+A+E L K+G +++IGVSNF    LE LL+ A +KP+VNQV
Sbjct: 115 -----GKDK-----YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQV 164

Query: 593 ECHPYLNQKRLKEF 634
           E HP L QK L+++
Sbjct: 165 EFHPRLTQKELRDY 178


>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 320

 Score =  154 bits (374), Expect = 1e-36
 Identities = 80/199 (40%), Positives = 116/199 (58%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           M+ K+P+ T +NG  +P  GLGTW+    E    +++A+  GYRHID A +Y NE ++G+
Sbjct: 1   MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGD 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
           A+     EG++ RED+FIT+K +     PD+V  AL+ +L  L + Y+DLYL H P + K
Sbjct: 61  ALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTK 120

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
           +DGS            SDV   D W+  E +   GL K+IGVSNFN  Q+ R++    V 
Sbjct: 121 DDGSF----------RSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVP 170

Query: 575 PVVNQVECHPYLNQKRLKE 631
              +Q+E H YL QK  +E
Sbjct: 171 IHASQLELHLYLPQKAHRE 189


>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
           niger|Rep: Putative frameshift - Aspergillus niger
          Length = 357

 Score =  154 bits (374), Expect = 1e-36
 Identities = 80/193 (41%), Positives = 117/193 (60%), Gaps = 1/193 (0%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T N G  IP  G+GT++  P    + V   +  G R ID A VYG E++VG  I    K+
Sbjct: 39  TLNTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGI----KK 93

Query: 239 GVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
             V RE++F+ +KLW N FH PD V  A+ ++L +L   Y+DL L+H+P  +K     FP
Sbjct: 94  SGVPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFP 152

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
            D  G++   +  +VDTW+A+E +VK G V++IGVSNF+  ++E LL+  +  P V+Q+E
Sbjct: 153 RDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQME 212

Query: 596 CHPYLNQKRLKEF 634
            HPYL QK   E+
Sbjct: 213 VHPYLQQKGFNEW 225


>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
           Aldehyde reductase - Leptospira interrogans
          Length = 278

 Score =  154 bits (373), Expect = 2e-36
 Identities = 83/203 (40%), Positives = 120/203 (59%), Gaps = 1/203 (0%)
 Frame = +2

Query: 29  SKMAPKIPVVTFNNGETIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKE 205
           +K  P    +  NNG ++P+ GLG WK+K G E  +AV +A++ GYRHID A +Y NE +
Sbjct: 3   NKENPLKQTIMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVD 62

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
           VG+AI    +E  + R+++FIT+KLWN     D  R AL+ +LD L + ++DLYLIH+P 
Sbjct: 63  VGQAI----RESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPV 118

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
             K                     +D+WK +E L  + L K+IGVSN+    L  LL+++
Sbjct: 119 TSKR--------------------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNS 158

Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634
            + P VNQVE HP+LNQ  L E+
Sbjct: 159 QITPAVNQVEFHPFLNQIHLLEY 181


>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
           str. PEST
          Length = 310

 Score =  153 bits (372), Expect = 3e-36
 Identities = 80/202 (39%), Positives = 115/202 (56%), Gaps = 2/202 (0%)
 Frame = +2

Query: 35  MAPKIPV-VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211
           M PK  + ++  +   +P  GLGT+     +  +A++ AID+GYR  D A  YGNE  VG
Sbjct: 1   MIPKTCINLSDQHSIALPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVG 60

Query: 212 EAITSKIKE-GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388
           EAI  KI+E   +TR+D FI SKL  ++HR DLV    + TLD L + Y+DLYL+H P A
Sbjct: 61  EAIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVA 120

Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
            + +                +   + W  +E   +EGL +SIGVSNFN  Q+  LL  A+
Sbjct: 121 LQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDAS 180

Query: 569 VKPVVNQVECHPYLNQKRLKEF 634
           + P VNQ+EC    NQ+ +++F
Sbjct: 181 IVPAVNQIECSIGFNQRPMRKF 202


>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Opitutaceae bacterium TAV2
          Length = 347

 Score =  153 bits (371), Expect = 3e-36
 Identities = 80/202 (39%), Positives = 115/202 (56%), Gaps = 5/202 (2%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGTWKSK---PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           KIP  T  +G  +P  G+GT+ S    PGEV  +V  A ++GYRH DCA VY NE+E+G 
Sbjct: 15  KIPQRTLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGA 74

Query: 215 AITSKIKEGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP-QA 388
                +     + REDL+ITSKLWN  H    V  A +++L +L + YLDLYLIHWP   
Sbjct: 75  TFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPN 134

Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
           +   G    +       +   +++ TW+ +E L   GLV+ IG SN    +L+ LL+ A 
Sbjct: 135 FHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDAR 194

Query: 569 VKPVVNQVECHPYLNQKRLKEF 634
           V+P VN++E HP+  Q  L ++
Sbjct: 195 VRPAVNEMELHPHFQQPALFDY 216


>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
           cellular organisms|Rep: Prostaglandin f synthase,
           putative - Leishmania major
          Length = 279

 Score =  153 bits (371), Expect = 3e-36
 Identities = 81/200 (40%), Positives = 115/200 (57%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MA K   VT +NG  +P  G+GTW++K G     +K A++ GYRH+D A+ Y NEK VG+
Sbjct: 1   MAVKCTHVTLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQ 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
            I+    E  V R D+F+T+KLWN  H  +    A +++   L V+Y+DLYLIHWP   +
Sbjct: 61  GIS----ECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWPGPNR 116

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
                               Y++TW+A E L +   V++IGVSNF    L+ LL + TV 
Sbjct: 117 -------------------SYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVP 157

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P+VNQVE HP+  QK L+ +
Sbjct: 158 PMVNQVEMHPHFQQKALRAY 177


>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
           Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
           Leishmania major strain Friedlin
          Length = 372

 Score =  153 bits (371), Expect = 3e-36
 Identities = 84/195 (43%), Positives = 108/195 (55%), Gaps = 12/195 (6%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +   +  TIP  G GT++    E T AV  A+  GYRH+DCA  YGNE  VGEA+   ++
Sbjct: 22  IAMRDSHTIPQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALR 81

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA------YKE 397
                REDLF+TSKLW T   PD V  A + TL  L + YLDLYLIHWP        +  
Sbjct: 82  TRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTS 141

Query: 398 DGSLFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH-ATV 571
           D   +P  + G     + V  +DTW AM  LV  GLVKSIG++N  +  +  L++  A  
Sbjct: 142 DEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEA 201

Query: 572 K----PVVNQVECHP 604
           K    PV+NQVE HP
Sbjct: 202 KLAHLPVLNQVEHHP 216


>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
           Saccharomycetaceae|Rep: Glycerol dehydrogenase -
           Zygosaccharomyces rouxii (Candida mogii)
          Length = 310

 Score =  153 bits (371), Expect = 3e-36
 Identities = 87/200 (43%), Positives = 123/200 (61%), Gaps = 10/200 (5%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N G+TIP  GLGTW+SK  E  +AV +A+  GYRHID A VYGNE EVG+A    I++  
Sbjct: 14  NTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA----IQDSG 69

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK----EDGSLF 412
           V R ++F+T+KLW T  R    + AL ++L  L + Y+ LYL+HWP   +    +DG+LF
Sbjct: 70  VPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLRTENIKDGNLF 127

Query: 413 ----PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK-- 574
                 D S  +   + +++ TW+ M+ L++ G  K+IGVSNF+   L+ LL   T K  
Sbjct: 128 QFAEKPDGSKDVDL-EWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLLAAPTTKVT 186

Query: 575 PVVNQVECHPYLNQKRLKEF 634
           P VNQVE HP L Q+ L ++
Sbjct: 187 PAVNQVEFHPLLPQEELIQY 206


>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
           n=2; Parasitella parasitica|Rep:
           4-dihydromethyltrisporate dehydrogenase - Parasitella
           parasitica
          Length = 321

 Score =  153 bits (371), Expect = 3e-36
 Identities = 80/190 (42%), Positives = 109/190 (57%), Gaps = 6/190 (3%)
 Frame = +2

Query: 74  ETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 253
           + +P+ G G WK +  +    +  AI IGYR  D A  YGNE EVG  I   IKEG+V R
Sbjct: 13  DKMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKR 72

Query: 254 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW--PQAYKEDGSLFPTD-- 421
           E+LFI +KLWNTFH    VR A    L +  ++Y DLYLIH+  P  Y +    +P +  
Sbjct: 73  EELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWY 132

Query: 422 --QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
              + K+ F      + W  ME LV+  L ++IGV+NFN + +  LL +A +KP V Q+E
Sbjct: 133 VPHADKLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIE 192

Query: 596 CHPYLNQKRL 625
            HP L Q+RL
Sbjct: 193 IHPLLPQERL 202


>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 324

 Score =  153 bits (371), Expect = 3e-36
 Identities = 82/196 (41%), Positives = 120/196 (61%), Gaps = 6/196 (3%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N+G +IP  GLGT  +  G V + V  AI  GYRHID A++YG+E +VG+ I   I E +
Sbjct: 10  NDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEEL 67

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG----SLF 412
           V RE+LF+T+K+W TF+  + V  +L  +L +L++ Y+DL L+HWP +   D     +++
Sbjct: 68  VKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAIY 125

Query: 413 PTDQSGKIQFSDV--DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
             +  G +++SD   D++ T+K +E     G  KSIGVSN +   L+RLL      P VN
Sbjct: 126 LVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVPAVN 185

Query: 587 QVECHPYLNQKRLKEF 634
           Q E HPYL QK+  EF
Sbjct: 186 QFEIHPYLPQKKEIEF 201


>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
           Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
          Length = 312

 Score =  152 bits (369), Expect = 6e-36
 Identities = 86/205 (41%), Positives = 122/205 (59%), Gaps = 11/205 (5%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           +++ N G  IP  GLGTW+SK  +  +AV  A+  GYRHID A +Y NE +VG+A    I
Sbjct: 11  ILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQA----I 66

Query: 233 KEGVVTREDLFITSKLWNT-FHRPDLVRGALQETLDNLNVQYLDLYLIHWP----QAY-- 391
           K+  V RE++F+T+KLW T  H P++   AL ++L  L + Y+DLYL+HWP     AY  
Sbjct: 67  KDSGVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPAYIK 123

Query: 392 KEDGSLFPTDQSGK--IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--Q 559
            ED    PT + G   +  ++ +++ TW+ M+ L K G  K++GVSNF+   L+ LL  Q
Sbjct: 124 NEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQ 183

Query: 560 HATVKPVVNQVECHPYLNQKRLKEF 634
              + P  NQVE HP L Q  L  F
Sbjct: 184 GNKLTPAANQVEIHPLLPQDELINF 208


>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Exiguobacterium sibiricum 255-15
          Length = 274

 Score =  152 bits (368), Expect = 8e-36
 Identities = 80/193 (41%), Positives = 114/193 (59%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           VT NNG  +P  G G +K    EV +AV++A+ +GYR ID A +Y NE  VG A    +K
Sbjct: 4   VTLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRA----LK 59

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
           +  + RED+F+T+K+WN     +    A + +L  L V Y+DLYLIHWP     D  L  
Sbjct: 60  DSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---PDEDL-- 114

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                        Y+DTW+A+E L ++G  K+IGVSNF+   L R+L+  TV P VNQ+E
Sbjct: 115 -------------YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIE 161

Query: 596 CHPYLNQKRLKEF 634
            HP+L+Q+ ++ F
Sbjct: 162 LHPFLSQEAIRAF 174


>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
           - Apis mellifera
          Length = 321

 Score =  151 bits (366), Expect = 1e-35
 Identities = 75/191 (39%), Positives = 119/191 (62%), Gaps = 2/191 (1%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           NGE +P+ G GTW+++  E+  A+  A++ GYRHID A  Y NEK +G+ + +      +
Sbjct: 10  NGELMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKKL 69

Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTDQ 424
            R D+FI +KL    +R + V   ++ +L NL ++YLDLYLIH P  +++ G  L P D+
Sbjct: 70  KRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFDE 129

Query: 425 SGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
           +G I+  +  ++V+ W  ME  VK G  K+IG+SNFN  Q++R+L++  +K  + Q+E H
Sbjct: 130 NGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIELH 189

Query: 602 PYLNQKRLKEF 634
            Y  QK L +F
Sbjct: 190 VYFQQKELVKF 200


>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Staphylococcus|Rep: Oxidoreductase,
           aldo/keto reductase family - Staphylococcus epidermidis
           (strain ATCC 35984 / RP62A)
          Length = 279

 Score =  151 bits (366), Expect = 1e-35
 Identities = 79/194 (40%), Positives = 113/194 (58%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           V   NNG  +P  GLG +K    ++ + V+ A+D GYR  D AY YGNEK +G A+    
Sbjct: 5   VQILNNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSAL---- 60

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
           K   V R++LFITSKLWN +   D       ++LDNL + YLDL+LIHWP          
Sbjct: 61  KHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCE-------- 112

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                     +D  Y++++KA+E L +EG +K+IGV NF    LE+L++   + P VNQ+
Sbjct: 113 ----------NDQLYIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQI 162

Query: 593 ECHPYLNQKRLKEF 634
           E HPY NQ+ +++F
Sbjct: 163 ELHPYFNQQDVQDF 176


>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
           Actinomycetales|Rep: Putative oxidoreductase -
           Streptomyces coelicolor
          Length = 277

 Score =  151 bits (365), Expect = 2e-35
 Identities = 82/199 (41%), Positives = 111/199 (55%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           M+ K+P +  NNG  +P  G G W+    +   AV  A++ GYR ID A +YGNE+  G 
Sbjct: 1   MSSKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGR 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
           AI +      + REDLF+T+KLWN+    D    A   ++  L ++YLDLYLIHWP   K
Sbjct: 61  AIAA----SGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAK 116

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
           E                   YVDT+KA E L+ +G V++IGVSNF  + LERL    +V 
Sbjct: 117 E------------------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVI 158

Query: 575 PVVNQVECHPYLNQKRLKE 631
           P VNQ+E HP+L Q   +E
Sbjct: 159 PAVNQIELHPHLQQHAARE 177


>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
           reductase family - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 279

 Score =  150 bits (363), Expect = 3e-35
 Identities = 82/193 (42%), Positives = 109/193 (56%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           VT NNG  IP  GLG ++    E  + V++ I  GYR ID A +YGNE   G  I + + 
Sbjct: 9   VTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLA 68

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
              + REDLF+TSK+WN     D    A  ++L+ L + YLDLYLIHWP           
Sbjct: 69  ATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP----------- 117

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                     +  Y ++W+A+E L  EG VK+IGVSNF    LE LL +A V PV+NQVE
Sbjct: 118 ---------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVE 168

Query: 596 CHPYLNQKRLKEF 634
            HP L+QK +++F
Sbjct: 169 LHPKLDQKEVRDF 181


>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus acidophilus
          Length = 285

 Score =  149 bits (361), Expect = 5e-35
 Identities = 77/183 (42%), Positives = 115/183 (62%), Gaps = 1/183 (0%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           T NNG  IP+ G GTW++  GEV + +V  A++ GYRHID A  YGNE  VG AI    K
Sbjct: 11  TLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ---K 67

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
            G+  R +LFIT+KLWN+ H  +  + A+ ++L +L + YLD+YLIHW           P
Sbjct: 68  SGI-NRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHW-----------P 115

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
              S +  +++++  ++W+AME  V+ G +++IGVSNF    L+ L++ A +KPVVNQ+ 
Sbjct: 116 NPSSMRDHWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIF 174

Query: 596 CHP 604
            +P
Sbjct: 175 LNP 177


>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
           Orconectes limosus|Rep: Aldoketoreductase-like protein -
           Orconectes limosus (Spinycheek crayfish)
          Length = 336

 Score =  149 bits (361), Expect = 5e-35
 Identities = 82/204 (40%), Positives = 118/204 (57%), Gaps = 7/204 (3%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205
           KIP +  N+G  IPV GLGT       K     VT  ++ A++ GYRH D A  YGNE  
Sbjct: 10  KIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAI 69

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
           +G+ +   I EG V RE+LFIT+KL    +R   V   LQ++LDNL + Y+DLYL+H+P 
Sbjct: 70  IGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPC 129

Query: 386 AYKE-DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
              + D      D+      +D+  +  W+AME  +  G  K+IG+SNFN+ Q++R+++ 
Sbjct: 130 GILDTDRERLSADEVTVDPTTDIHAI--WRAMEAQLAAGKTKNIGLSNFNADQVQRIIKG 187

Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634
             V+P V QVE H Y+ Q  L+ F
Sbjct: 188 CQVRPAVLQVEVHVYMQQGALRAF 211


>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
           protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
           family 1 member C-like protein 1 - Homo sapiens (Human)
          Length = 302

 Score =  149 bits (361), Expect = 5e-35
 Identities = 87/198 (43%), Positives = 112/198 (56%), Gaps = 5/198 (2%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           V  N+G  +PV G GT+    +   +  +A K AID+G+RHID AY+Y NE+EVG+AI  
Sbjct: 11  VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 403
           KI +G V RE++F T KLW TF R +LV  AL+ +L  L   Y+DL++IH P A K+ G 
Sbjct: 71  KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGK 130

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
            L P D SG+I    V+  DTW+    L K GL                       KP  
Sbjct: 131 ELLPKDASGEIILETVELCDTWELELILNKPGL---------------------RYKPTC 169

Query: 584 NQ-VECHPYLNQKRLKEF 634
           NQ VECHPYLNQ +L EF
Sbjct: 170 NQVVECHPYLNQSKLLEF 187


>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG2767-PA - Nasonia vitripennis
          Length = 356

 Score =  149 bits (360), Expect = 7e-35
 Identities = 76/195 (38%), Positives = 118/195 (60%), Gaps = 3/195 (1%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +  ++G  +P+ GLGTW+  P  +  AV  A++ GYRHID A+ YGNE+ +G+ +     
Sbjct: 28  IKLSSGHDMPMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFD 87

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
           +G   REDLFIT+KL     R + V   L+ +L+ L ++Y+++YLIH P A+ +D   + 
Sbjct: 88  KGG-KREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYE 146

Query: 416 T--DQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
              +  G +   +D D+V  W+AME  VK G V+SIG+SNFN  QL  + +HA +KP   
Sbjct: 147 PALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAEIKPSNL 206

Query: 587 QVECHPYLNQKRLKE 631
           Q+E   Y  Q+ ++E
Sbjct: 207 QIELQAYNQQRPMRE 221


>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 295

 Score =  148 bits (359), Expect = 1e-34
 Identities = 78/190 (41%), Positives = 116/190 (61%), Gaps = 1/190 (0%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NG  +PVFGLGT+K     E+   ++ A+D+GYRHID A +Y NEK++G+A+    KEG 
Sbjct: 12  NGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYKEGK 71

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
             REDLF+ +KL++  ++   V   ++++L NL   Y+DLYL+H+        S  PTDQ
Sbjct: 72  YKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHY-------ASSPPTDQ 122

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
               + +       W   E LV++GL+++IG+SNFN + L  L  +  +KPVVNQ+E + 
Sbjct: 123 ---FELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNV 179

Query: 605 YLNQKRLKEF 634
           Y  Q RL EF
Sbjct: 180 YCQQPRLLEF 189


>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 310

 Score =  147 bits (357), Expect = 2e-34
 Identities = 84/203 (41%), Positives = 126/203 (62%), Gaps = 3/203 (1%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVG 211
           + P I  +  NNG  +P+ G+GT+K +  EV + V D +  +G+R ID A VY NE+++G
Sbjct: 19  LTPTIRDLRLNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIG 78

Query: 212 EAITSKIKEGVVTREDLFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388
            A+   + +  + RED+FITSKL  + +  PD +R +++++L  L+  YLDLYLIHWP A
Sbjct: 79  LALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGA 138

Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
            +    L  +  + K++      V TW  +  L ++GL++SIGVSN+    LE LL+H +
Sbjct: 139 SR---ILENSPDNPKLR------VTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCS 189

Query: 569 -VKPVVNQVECHPYLNQKRLKEF 634
            VKP VNQVECHP+  Q  L EF
Sbjct: 190 GVKPDVNQVECHPHFRQDELIEF 212


>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
           n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
           protein - Oryza sativa (Rice)
          Length = 337

 Score =  147 bits (357), Expect = 2e-34
 Identities = 85/204 (41%), Positives = 120/204 (58%), Gaps = 6/204 (2%)
 Frame = +2

Query: 38  APKIPVVTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           A  +P VT N+G  +PV G GT  S P  ++   +  A+ +GYRH+D A VYG E  VG 
Sbjct: 17  ATAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGA 76

Query: 215 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391
           A+   ++ G V +R +LF+T+KL      P  V  AL+E+L  L + Y+DL+LIHWP A 
Sbjct: 77  AVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAI 136

Query: 392 -KED--GSLFPTDQS-GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 559
            K+D  G L   D S G + F   D    W+ ME   + GL +SIGVSNF++ ++ RLL 
Sbjct: 137 GKKDAAGELTWDDLSRGLVPF---DMEGVWRGMEECHRLGLARSIGVSNFSAAKMSRLLA 193

Query: 560 HATVKPVVNQVECHPYLNQKRLKE 631
            A V P VNQVE +    Q++++E
Sbjct: 194 LAAVPPAVNQVEMNVGWRQEKVRE 217


>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 288

 Score =  147 bits (357), Expect = 2e-34
 Identities = 80/204 (39%), Positives = 116/204 (56%), Gaps = 8/204 (3%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWK-----SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211
           +P    ++G+ +P  G+GT       + P  V   V  AI+ GYRH D A VY  E  +G
Sbjct: 1   MPEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60

Query: 212 EAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388
           +A+   ++ G+V +R++L+ITSKLW     P  V  +L+  L  + ++YLDLYLIH+P +
Sbjct: 61  DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120

Query: 389 YK--EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
            +  ED       +   +    +D    WK ME   + GL K+IGVSNF+ K+LE LL  
Sbjct: 121 MRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSF 177

Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634
           AT+ P  NQVE HPY  Q +L+EF
Sbjct: 178 ATISPAANQVEVHPYCRQNKLREF 201


>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG6084-PA, isoform A - Tribolium castaneum
          Length = 493

 Score =  147 bits (356), Expect = 2e-34
 Identities = 85/203 (41%), Positives = 124/203 (61%)
 Frame = +2

Query: 26  ISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205
           +S+    IP+   NNG  IPVFGL   +    EV + V+  +   YR +DC+ ++ NEK 
Sbjct: 1   MSQKMRDIPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKR 57

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
            G A+   I+ G + R+DLF+ SK   T +  +LV+ AL +TL  L V YLDLYLI  P 
Sbjct: 58  FGVALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPP 116

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
           A K                 D + ++TW+AME L  E L ++IG+SNFNSKQ+ER+L++ 
Sbjct: 117 ACK-----------------DHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENC 159

Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634
           T++P VNQ++CHPYLNQ +L+++
Sbjct: 160 TIRPQVNQIQCHPYLNQAKLRKY 182



 Score =  138 bits (333), Expect = 1e-31
 Identities = 61/104 (58%), Positives = 81/104 (77%), Gaps = 1/104 (0%)
 Frame = +2

Query: 326 ETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGL 502
           E+L NL + YLD+YL+HWP A KE  SL P D ++G    SDVD+VDTWKAME + ++ L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330

Query: 503 VKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
            KSIG+SNFNS Q++RLL+ A + PV+NQ+ECHPYLNQ +L++F
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKF 374


>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
           Saccharomycetales|Rep: D-arabinose dehydrogenase -
           Pichia stipitis (Yeast)
          Length = 326

 Score =  147 bits (355), Expect = 3e-34
 Identities = 83/214 (38%), Positives = 130/214 (60%), Gaps = 11/214 (5%)
 Frame = +2

Query: 26  ISKMAPKIPVVTFNNGETIPVFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEK 202
           ++++A  +  V  +NG+TIP  GLGT   + P E+ + V  A+  GYRHID A+ YG E+
Sbjct: 1   MTQLATDVDFV-LSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEE 59

Query: 203 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382
            +G+A+    +EG+V REDLFIT+K+W +F R      +L ++L +L + Y+DL+L HWP
Sbjct: 60  YIGQALKQLFEEGIVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWP 117

Query: 383 QAYKEDGSLF---PTDQSGKIQFSD-----VDYVDTWKAMEPLV-KEGLVKSIGVSNFNS 535
                D +     P D+ GK+ + D     + Y+D + ++E ++     VKSIGVSN++ 
Sbjct: 118 VVLHGDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSI 177

Query: 536 KQLERLLQHATV-KPVVNQVECHPYLNQKRLKEF 634
            +L +LL      KPVVNQ+E HP L Q+ L ++
Sbjct: 178 PKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKY 211


>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep:
           2,5-didehydrogluconate reductase - Clostridium
           beijerinckii NCIMB 8052
          Length = 289

 Score =  146 bits (354), Expect = 4e-34
 Identities = 78/190 (41%), Positives = 112/190 (58%), Gaps = 1/190 (0%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NG  IP  G G +K   GE  + AV +AI IGYRH D A +YGNEK++G AI    ++  
Sbjct: 12  NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + RE+ FITSK+WNT H  +  + A ++T   LNV+YLD+YLIH+  +Y           
Sbjct: 68  IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
                     Y++TW AME L  +G +K IGV+NF  + LE L++H+ + P++NQ+E HP
Sbjct: 117 ----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHP 166

Query: 605 YLNQKRLKEF 634
              Q  L ++
Sbjct: 167 EFPQNELHQY 176


>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 360

 Score =  146 bits (354), Expect = 4e-34
 Identities = 80/181 (44%), Positives = 110/181 (60%), Gaps = 3/181 (1%)
 Frame = +2

Query: 83  PVFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256
           P+ G GTW  K  P   T+AV  AI+IGYR IDCA VYGNE  VG  I   +K   + RE
Sbjct: 40  PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99

Query: 257 DLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 433
           D+++TSKLWN  H   + V   L +TL +L ++YLDLYLIHWP  +  +G+         
Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA--------- 150

Query: 434 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 613
               ++D+V T+K+M  L K   V +IGVSNF+  QL+ ++   T+ P ++Q+E HPYL 
Sbjct: 151 ---KNLDHVQTYKSMISLPK-SRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQ 205

Query: 614 Q 616
           Q
Sbjct: 206 Q 206


>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
           reductase; n=1; Gluconobacter oxydans|Rep: Putative
           2,5-diketo-D-gluconic acid reductase - Gluconobacter
           oxydans (Gluconobacter suboxydans)
          Length = 279

 Score =  145 bits (351), Expect = 9e-34
 Identities = 79/194 (40%), Positives = 110/194 (56%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           V++F++G T+P  GLG W++ P E  + VK+A+ +GYR +D A +Y NE+ VG       
Sbjct: 13  VISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVG------- 65

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
            +G+    ++F+T+KLWN     D    A +E+   L    LDLYLIHWP          
Sbjct: 66  -KGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP-------- 116

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                     +   YV+TWKA+  L K G VKSIGVSNF S+ LER++    V PVVNQ+
Sbjct: 117 ----------AQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQI 166

Query: 593 ECHPYLNQKRLKEF 634
           E HP   Q+ L+EF
Sbjct: 167 ELHPDFQQRALREF 180


>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
           djamor|Rep: Reductase AKOR2 - Pleurotus djamor
          Length = 306

 Score =  145 bits (351), Expect = 9e-34
 Identities = 83/199 (41%), Positives = 116/199 (58%), Gaps = 7/199 (3%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKD----AIDIGYRHIDCAYVYGNEKEVGEA 217
           P +  N G  +P   LG W     E     K+    A+  GYRHID A +Y  EK VG A
Sbjct: 5   PPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVGNA 64

Query: 218 ITSKIKEGVVTREDLFITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ-AY 391
           I    +E  + RE+LFIT+KL WN   R   V  + Q++L+NL  +Y+DLYL+H+PQ  +
Sbjct: 65  I----RESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFPQRVF 117

Query: 392 KEDGSLFPTDQSGKIQFSDVDYV-DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
            ++ + FP +  G I+  +   + D W  +E L+  G VK+IGVSN++ K LE LL+ A 
Sbjct: 118 YDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELLKTAK 177

Query: 569 VKPVVNQVECHPYLNQKRL 625
           V P VNQVE HP+L Q +L
Sbjct: 178 VVPAVNQVELHPFLAQSKL 196


>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 339

 Score =  145 bits (351), Expect = 9e-34
 Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 14/214 (6%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPG-----EVTQAVKDAIDIGYRHIDCAYVYGNE 199
           MA  IP  T N G  +P  G+G W+ +PG     E+  A+  AI +GYRH+D A  Y NE
Sbjct: 1   MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNE 60

Query: 200 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQE---TLDNLNVQYLDLYL 370
            EVG+A+    ++  V R ++F+T+KL     RP  V   +QE   +L+ L + Y+DL+L
Sbjct: 61  AEVGQAV----RQSGVARSEIFVTTKL-----RPGGVHDVVQELENSLNELGIDYIDLWL 111

Query: 371 IHWPQAYKEDGSLFPTDQSGKIQFSD---VDYVDTWKAMEPLV---KEGLVKSIGVSNFN 532
           +HWPQ + +D   F T +S  ++        + +TW  ME +     +G VK+IGVSNF+
Sbjct: 112 LHWPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFS 171

Query: 533 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
            K LE L + + V P VNQ+E HPYL +  L ++
Sbjct: 172 IKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKY 205


>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 286

 Score =  144 bits (348), Expect = 2e-33
 Identities = 79/197 (40%), Positives = 114/197 (57%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           ++P VT NNG  +P+ G G ++  P +  + V +AI +GYR ID A  Y NE+ VG AI 
Sbjct: 2   QVPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIK 61

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
             I EG+V RE+LF+T+KLW +    +  + A +++L  L ++Y+DLYLIH P       
Sbjct: 62  RAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP------- 114

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
                       F DV     WKAME + K+GLV++IGVSNF   +L  L+ H  + P V
Sbjct: 115 ------------FGDVHC--AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAV 160

Query: 584 NQVECHPYLNQKRLKEF 634
           NQ+E HP+  ++   EF
Sbjct: 161 NQIEIHPFYQRQEEIEF 177


>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
           ATCC 50803
          Length = 303

 Score =  144 bits (348), Expect = 2e-33
 Identities = 76/188 (40%), Positives = 101/188 (53%), Gaps = 4/188 (2%)
 Frame = +2

Query: 83  PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 256
           P  G GT+  +  E   A++ A+ +GYRH DCAY YGNE+ +GE       +    V RE
Sbjct: 6   PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSG 430
           DL+I SKLW  FH P+ V   + ETL +L ++YLD++L+HWP A K   D     +D  G
Sbjct: 63  DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610
                      TW+AME  V +   + IGVSN  +  L  LL +  +KP  NQ E  PY 
Sbjct: 123 GTLLGTTPIRKTWEAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYF 182

Query: 611 NQKRLKEF 634
              RL EF
Sbjct: 183 PNDRLIEF 190


>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
           Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
           reductase - Tropheryma whipplei (strain Twist)
           (Whipple's bacillus)
          Length = 283

 Score =  142 bits (345), Expect = 5e-33
 Identities = 77/193 (39%), Positives = 116/193 (60%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           +P V   +G +IP FGLGT++  P E +  V+ AI++GYRHID A +Y NE+EVG AI S
Sbjct: 9   VPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRAIAS 68

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
                 + RE+ F+T+KLWN+  +P   R A + +LD L++ Y+DLYLIHWP        
Sbjct: 69  ----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWPCP------ 116

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
             P++           Y++ W+ +  L + G  KS+GVSNF S+ ++++ +     P VN
Sbjct: 117 --PSEL----------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVN 164

Query: 587 QVECHPYLNQKRL 625
           Q+E HP+L Q+ L
Sbjct: 165 QIELHPWLQQREL 177


>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 322

 Score =  142 bits (344), Expect = 6e-33
 Identities = 77/193 (39%), Positives = 108/193 (55%), Gaps = 1/193 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           +  NNG+ IP   LG +K+   G    A K A D GYRHID A  Y NE+ VG A+    
Sbjct: 19  IKLNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWT 78

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
           KE  V R ++FITSKLW+  H  D    A++++L  LNV Y+D+YL+H P     +  L 
Sbjct: 79  KENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKRL- 135

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                           + WKA+E  V  G +K+IGVSNF+ ++L+ LL +  +KP VNQ+
Sbjct: 136 ----------------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQI 179

Query: 593 ECHPYLNQKRLKE 631
           E HP+   + L+E
Sbjct: 180 ESHPFFAHEELRE 192


>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 286

 Score =  142 bits (343), Expect = 8e-33
 Identities = 78/183 (42%), Positives = 105/183 (57%), Gaps = 1/183 (0%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           T NNG  IP+ G GTW++  G+V   +V  A+  GYRHID A  YGNE+ VG+AI     
Sbjct: 12  TLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA---- 67

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
           +  V REDLF+T+KLWN  H  D  + AL  +L  L + Y+DLYLIHWP           
Sbjct: 68  DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNP--------- 118

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
              + +  +  ++  DTW+AME        ++IGVSNF  K L+ LL+ A V P VNQ+ 
Sbjct: 119 --AAMRDNWEQLN-ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIF 175

Query: 596 CHP 604
            +P
Sbjct: 176 LNP 178


>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase A - Corynebacterium sp. (strain ATCC 31090)
          Length = 278

 Score =  141 bits (341), Expect = 1e-32
 Identities = 75/196 (38%), Positives = 109/196 (55%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           +P +  N+G +IP  G G +K  P +  +AV++A+++GYRHID A +YGNE+ VG AI +
Sbjct: 3   VPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAA 62

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
                 + R+DLFIT+KLWN  H  D    A+ E+L  L +  +DLYL+HWP    +   
Sbjct: 63  ----SGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAAD--- 115

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
                          +YV  W+ M  L   GL +SIGVSN     LER++    V P VN
Sbjct: 116 ---------------NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVN 160

Query: 587 QVECHPYLNQKRLKEF 634
           Q+E HP   Q+ + ++
Sbjct: 161 QIELHPAYQQREITDW 176


>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Opitutaceae bacterium TAV2
          Length = 334

 Score =  140 bits (340), Expect = 2e-32
 Identities = 79/196 (40%), Positives = 110/196 (56%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP +  ++G +IP  GLG W+         ++ A + GYR ID A +YGNE+ VG AI  
Sbjct: 59  IPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRAI-- 116

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
             +   + R++L+IT+K+WN+    D    A++E+L  L ++Y+DLYLIHWP        
Sbjct: 117 --RASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPVP------ 168

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
                   KI      YVDTWKA+  +  +GL +SIGVSNF    L+RL     + PVVN
Sbjct: 169 --------KID----RYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVN 216

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HP L Q  L+ F
Sbjct: 217 QVELHPRLQQHELRAF 232


>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
           1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
           oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
          Length = 321

 Score =  140 bits (340), Expect = 2e-32
 Identities = 75/190 (39%), Positives = 115/190 (60%), Gaps = 4/190 (2%)
 Frame = +2

Query: 74  ETIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           +T+P  G+GT     +   + T A+  AI++GYRH D A +Y  E  VGEA+   ++ G+
Sbjct: 14  QTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGL 73

Query: 245 V-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
           + +R D+F+TSK+W +      V  A +ETL NL + Y+DL L+HWP +       FP  
Sbjct: 74  IASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFP 133

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
           +   +   D++ V  W+ ME   + GL ++IGVSNF++K+LE+LL  A V+P VNQVE +
Sbjct: 134 KEVILPSFDMEGV--WRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVN 191

Query: 602 PYLNQKRLKE 631
           P   Q+ L+E
Sbjct: 192 PMWQQRTLRE 201


>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
           Corynebacterium|Rep: Putative oxidoreductase -
           Corynebacterium diphtheriae
          Length = 290

 Score =  140 bits (339), Expect = 3e-32
 Identities = 71/190 (37%), Positives = 111/190 (58%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP +T N+G  +P  G GT+K +  +  +AV+ AI++GYRHID A +Y NE+EVG A+  
Sbjct: 11  IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
            I  G V R++LFIT+K+WN  H   L + + QE+L  L + Y+D  ++HWP        
Sbjct: 71  AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP-------- 122

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
            +P  Q G        YV+++ A+  +   G ++S+ V+NF  + L  ++    + PV+N
Sbjct: 123 -WP--QKGL-------YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLN 172

Query: 587 QVECHPYLNQ 616
           QVE HP  +Q
Sbjct: 173 QVELHPGFSQ 182


>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 353

 Score =  140 bits (338), Expect = 3e-32
 Identities = 77/197 (39%), Positives = 112/197 (56%), Gaps = 3/197 (1%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           V   ++G   P+ GLGT       +   +  A++ G  HID ++VY NE+ +G+ +    
Sbjct: 30  VYRLSSGHNFPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWF 89

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDGS 406
            +G   RED+F+TSKL    + P+ V   ++ +L+ L +QYLD+YLIH P A  +KED  
Sbjct: 90  AKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSY 148

Query: 407 LFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
              T++ G +   +  D +  WK ME  VKEG  KSIG+SNFN  Q+  +L+ A +KP  
Sbjct: 149 ELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSN 208

Query: 584 NQVECHPYLNQKRLKEF 634
            QVE H Y  QK L EF
Sbjct: 209 LQVEVHAYHQQKPLIEF 225


>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Yersinia pestis
          Length = 277

 Score =  139 bits (337), Expect = 4e-32
 Identities = 76/193 (39%), Positives = 111/193 (57%), Gaps = 1/193 (0%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P++   +G  +P  GLG W++   E   AV  A+++GYR ID A +Y NE+ VG+A    
Sbjct: 5   PLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA---- 60

Query: 230 IKEGVVTREDLFITSKLWN-TFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
           +K   V R++LFIT+KLWN   H P   + AL+ +L  L + Y+DLYLIHWP   K+D  
Sbjct: 61  LKAAAVARDELFITTKLWNDDQHNP---QQALETSLQKLQLDYVDLYLIHWPDP-KQD-- 114

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
                           YV  W+ +  L ++GL++SIGV NF+   L+RL+    + P VN
Sbjct: 115 ---------------HYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVN 159

Query: 587 QVECHPYLNQKRL 625
           Q+E HP L Q++L
Sbjct: 160 QIELHPLLQQRQL 172


>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
           2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
           oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
          Length = 322

 Score =  138 bits (335), Expect = 8e-32
 Identities = 76/189 (40%), Positives = 110/189 (58%), Gaps = 4/189 (2%)
 Frame = +2

Query: 77  TIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           T+P  G+GT     +   E T A+  AI++GYRH D A +Y  E  V EA+   ++ G+V
Sbjct: 17  TMPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLV 76

Query: 248 -TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
            +R D+F+TSKLW +      V  A +ETL NL + Y+DL L+HWP         FP  +
Sbjct: 77  ASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
                  D++ V  W+ ME   + GL ++IGVSNF++K+LE+LL  A V+P  NQVE +P
Sbjct: 137 EEMAPAFDMEGV--WRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNP 194

Query: 605 YLNQKRLKE 631
              Q+ L+E
Sbjct: 195 MWQQRTLRE 203


>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
           aldo/keto reductase family protein - Tetrahymena
           thermophila SB210
          Length = 297

 Score =  138 bits (333), Expect = 1e-31
 Identities = 77/198 (38%), Positives = 115/198 (58%), Gaps = 1/198 (0%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           K+P++ F  G +IP  G GT++ +  +    V +A+ IGY HID A VY NE+++ + I 
Sbjct: 12  KVPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIH 71

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
           +      + REDLFITSK+       +  + A+Q+ L  LN++YLD  LIHWP   K   
Sbjct: 72  NPAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK--- 126

Query: 404 SLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580
            L P D ++ +I+      ++TWKA+  L K G++K IGVSNFN   L+ L++ +  KP 
Sbjct: 127 -LPPNDPKNAQIR------LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPE 179

Query: 581 VNQVECHPYLNQKRLKEF 634
           +NQ E HP    K+  EF
Sbjct: 180 MNQFEIHPLCFNKKTIEF 197


>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Oceanobacillus iheyensis
          Length = 280

 Score =  137 bits (332), Expect = 2e-31
 Identities = 79/195 (40%), Positives = 105/195 (53%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           M  +IP VT ++G TIP  G GT++    +  QA+ +AID GYR ID AY Y NE  VGE
Sbjct: 1   MVNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGE 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
           A    ++     RE L ITSKL   +H  D     +QE+L   N+ Y DLYLIHWP    
Sbjct: 61  A----VRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPN--- 113

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
                            D+ YV+ W+A+    + G ++SIGV NF  + LERL Q     
Sbjct: 114 --------------PIQDI-YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGEL 158

Query: 575 PVVNQVECHPYLNQK 619
           P +NQ+E HP+ NQ+
Sbjct: 159 PTINQIELHPFFNQE 173


>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=3; Lactobacillales|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 292

 Score =  137 bits (332), Expect = 2e-31
 Identities = 77/189 (40%), Positives = 108/189 (57%), Gaps = 1/189 (0%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           T  +G  +P+ G G ++  + G   QAV DAI  GYR ID A  YGNE+EVGEAI   I 
Sbjct: 5   TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
           +G+V RE+LF+TSK+W           A+Q +L  LN+ YLDLYLIH P           
Sbjct: 65  QGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP----------- 113

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                   ++DV     W+AME   + G +K+IGVSNF+  QL  L + + +KP++NQ+E
Sbjct: 114 --------YNDV--FGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIE 163

Query: 596 CHPYLNQKR 622
            +P+   K+
Sbjct: 164 VNPFQQNKK 172


>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
           700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
          Length = 280

 Score =  136 bits (330), Expect = 3e-31
 Identities = 81/193 (41%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAV-KDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           N+G  IP+ G GT+K+   E  +++ K A+ +GYR ID   +Y NE+ VG+AI ++   G
Sbjct: 6   NDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---G 62

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
           V+ RE++F+T+KLW         R AL E+L  L++ Y+DLYLIHWP             
Sbjct: 63  VL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWP------------- 108

Query: 422 QSGKIQFSD--VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
            +  I + D      DTW+AME L  EG +KS+GVSNF  + LE L Q A V P VNQ+E
Sbjct: 109 -ANAINYKDWQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIE 167

Query: 596 CHPYLNQKRLKEF 634
            HP   Q ++ EF
Sbjct: 168 FHPGYWQPQVTEF 180


>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
           Aldo/keto reductase - Kineococcus radiotolerans SRS30216
          Length = 343

 Score =  136 bits (330), Expect = 3e-31
 Identities = 72/197 (36%), Positives = 106/197 (53%), Gaps = 4/197 (2%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217
           +P      G T+P  G+GT+ S    P EV  AV  A+  GYR +DCA VYGNE +VGEA
Sbjct: 13  VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72

Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397
           +   +  G V R++LF+ SK+WN  H P     ++  +L +L + +LD   +HWP     
Sbjct: 73  LAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPNHH 131

Query: 398 DGSLFPTDQSGKIQFSDVD-YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
                   +  + +  D D Y+  W A+E LV  GLV+ +G SN    +L+ LL+ A + 
Sbjct: 132 PPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDARIP 191

Query: 575 PVVNQVECHPYLNQKRL 625
           P +N++E HP   Q  L
Sbjct: 192 PALNEMELHPCFQQPEL 208


>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
           Lin2349 protein - Listeria innocua
          Length = 294

 Score =  136 bits (329), Expect = 4e-31
 Identities = 85/188 (45%), Positives = 106/188 (56%), Gaps = 1/188 (0%)
 Frame = +2

Query: 74  ETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250
           ETIP  GLG ++    E +  AV+ AI++GYR  D A VY NE  VG+AI     +  V 
Sbjct: 15  ETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVP 70

Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430
           RE+LFI+SK+WN     D    A + TL NL + YLDLYLIHWP A K            
Sbjct: 71  REELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK------------ 118

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610
                   Y D+W+AME L  E L+KSIGV+NF    L  LL  A  KPV+NQVE HP L
Sbjct: 119 --------YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLL 170

Query: 611 NQKRLKEF 634
            Q  L+++
Sbjct: 171 PQNDLRKY 178


>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
           precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
           complete genome. precursor - Aspergillus niger
          Length = 351

 Score =  136 bits (329), Expect = 4e-31
 Identities = 91/223 (40%), Positives = 120/223 (53%), Gaps = 12/223 (5%)
 Frame = +2

Query: 2   SSQAAAKIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGE--VTQAVKDAIDIGYRHID 175
           S   +A+II ++  +      +   T P  GLGT++   G   V +AV  A+  GYRHID
Sbjct: 21  SLSTSAEIIPELVHRFSFFPVSE-MTFPAVGLGTFQGDAGNRGVKEAVLQALRCGYRHID 79

Query: 176 CAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQY 355
            A  YGNE EVGEAI    KE  + RE++ +T+KL  T+HR   V  AL  +L+ L + Y
Sbjct: 80  TATAYGNEIEVGEAI----KESRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNY 135

Query: 356 -LDLYLIHW-----PQAYKE--DGSLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEGLV 505
            L ++L        P AY    D +         I   ++  DY  TW AME LV +G +
Sbjct: 136 GLSMHLYSASSYSVPHAYSPGPDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKL 195

Query: 506 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
           K IGVSNFN  +LERLL  A + P VNQ+E HPYL Q  L  F
Sbjct: 196 KMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVRF 238


>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Arthrobacter sp. (strain FB24)
          Length = 291

 Score =  136 bits (328), Expect = 5e-31
 Identities = 80/207 (38%), Positives = 112/207 (54%), Gaps = 13/207 (6%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT-- 223
           P ++ NNG  I   G G +K  P +    V  A++ GYRH D A +YGNE  VG+AI   
Sbjct: 5   PRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGAL 64

Query: 224 -----------SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYL 370
                      S      ++REDLF+T+K+WN  H  D    A   ++ NL ++Y+DLYL
Sbjct: 65  AGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYL 124

Query: 371 IHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLER 550
           IHWP A +    LF                ++++AME L +EG +++IGVSNF    LE 
Sbjct: 125 IHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGVSNFQPAHLEH 166

Query: 551 LLQHATVKPVVNQVECHPYLNQKRLKE 631
           LL+ A V P VNQ+E HP+L Q  L++
Sbjct: 167 LLETAEVVPAVNQIELHPWLQQDELRQ 193


>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 292

 Score =  134 bits (324), Expect = 2e-30
 Identities = 74/196 (37%), Positives = 106/196 (54%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP      G  IPV G GT+K  P +   AV  A+++GYRHID A +YGNE EVG A   
Sbjct: 16  IPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAA--- 72

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
            ++   + REDLFIT+K+ N+ H PD    +++ +L++L   Y+DL L+HWP        
Sbjct: 73  -LEASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP-------- 123

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
             PT   G       D    W A+E     G  ++IG+SN+  + +E + + ATV P V 
Sbjct: 124 -LPTLYGG-------DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVL 175

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HP+     L+ +
Sbjct: 176 QVESHPFFPNADLRAY 191


>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
           Mycoplasma gallisepticum
          Length = 289

 Score =  133 bits (322), Expect = 3e-30
 Identities = 79/201 (39%), Positives = 117/201 (58%), Gaps = 4/201 (1%)
 Frame = +2

Query: 44  KIPVVTFN---NGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVG 211
           KI V+ +N   N   +P  G GT+K + G+ T +AVK A+++GYRH+DCA +Y N+  V 
Sbjct: 7   KIKVMKYNLLANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVS 66

Query: 212 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391
           + I    K   V R+++FITSK+WN     +  + A  + L +L+++YLDL LIHWP   
Sbjct: 67  QGI----KLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPI-- 120

Query: 392 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571
              G  F      K  + +V+   TWKAME    EG +K+IG+SNF    +E L + A +
Sbjct: 121 ---GKGF------KDNWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKI 170

Query: 572 KPVVNQVECHPYLNQKRLKEF 634
            P+VNQ+E HP   Q  + E+
Sbjct: 171 LPMVNQLEFHPGYLQPEIVEY 191


>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 355

 Score =  132 bits (320), Expect = 5e-30
 Identities = 85/228 (37%), Positives = 114/228 (50%), Gaps = 29/228 (12%)
 Frame = +2

Query: 38  APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAID-----------------IGYR 166
           AP       N G  IPV GLGTW+S PGEV +AV+ AI                  +GY 
Sbjct: 8   APGQKTFKLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYV 67

Query: 167 HI----------DCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRG 316
            +          D A++YGNE EVG+ I    K   V R +LF+T+K+W T+HR      
Sbjct: 68  ALHPLYIPFLAKDAAWIYGNENEVGQGI----KASGVPRSELFVTTKIWCTYHRQP--EA 121

Query: 317 ALQETLDNLNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLV 490
            L E+L  L + Y+DL L+HWP    K      P ++ G      D     TW+ ME L 
Sbjct: 122 CLDESLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLP 181

Query: 491 KEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
             G  K+IGVSN++   L++LL  A + P  NQVE HP+L Q  L ++
Sbjct: 182 ATGKTKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKY 229


>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Bacteroides capillosus ATCC 29799
          Length = 287

 Score =  132 bits (319), Expect = 7e-30
 Identities = 77/190 (40%), Positives = 103/190 (54%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           +NG +IP  G GT+K+  G+ +  + +AI  GYRH D A  YG E  +G+A+     E  
Sbjct: 11  SNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ESD 65

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + RED F+TSKLW T    D    A   TL+ L   YLDLYLIHWP+   E       D+
Sbjct: 66  IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDLELEDWAKLDR 125

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
                       +TW+A+E L + GLV++IGVSNF    LE +L  A V P+V+Q+E HP
Sbjct: 126 ------------ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHP 173

Query: 605 YLNQKRLKEF 634
              Q     F
Sbjct: 174 GYTQDEAVAF 183


>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 323

 Score =  132 bits (318), Expect = 9e-30
 Identities = 77/204 (37%), Positives = 114/204 (55%), Gaps = 8/204 (3%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 208
           I  V  NNG  +P+ GLGT       +    E+T  + +A+D GYR+ D A  Y NE E+
Sbjct: 12  IKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEI 71

Query: 209 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388
           G+A  +  ++G   RED+FIT+KL+  F     ++  +Q +LD L   Y+DLYLI W   
Sbjct: 72  GQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQW--- 127

Query: 389 YKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
                S  P  T+  G +  +     + W+ +E  V+ G+++SIGV+NFN + +  LL +
Sbjct: 128 -----SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSY 182

Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634
           A +KPVVNQ+E  PYL Q  L  F
Sbjct: 183 AKIKPVVNQIEVTPYLPQIDLINF 206


>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
           reductase - Lactobacillus reuteri F275
          Length = 300

 Score =  132 bits (318), Expect = 9e-30
 Identities = 73/196 (37%), Positives = 106/196 (54%), Gaps = 1/196 (0%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P +  NNG  IP  GLG WK+   E  Q VK+AI   Y  ID A  YGNE  VG+ I   
Sbjct: 11  PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70

Query: 230 IKEGVVTREDLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
            K     R+ +F+T+K++N      D +R A+ E L  L   Y+DL L+HWP   K    
Sbjct: 71  FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDK---- 126

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
                           Y ++W+A+E + K+G  K+IGV NFN +++  LL HA +KP +N
Sbjct: 127 ----------------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAIN 170

Query: 587 QVECHPYLNQKRLKEF 634
           Q+E +P ++Q ++ +F
Sbjct: 171 QIEFNPLIHQPKIVKF 186


>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
           Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
           sp. (strain CCS1)
          Length = 276

 Score =  131 bits (317), Expect = 1e-29
 Identities = 69/193 (35%), Positives = 109/193 (56%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           PV+ F++G  IP  G G W+       + V+ AI+IGYR ID AY+Y NE  +GE     
Sbjct: 5   PVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG---- 60

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           ++   + R+++F+T+K+WN        R +++ +L  + V+ LDL LIHWP         
Sbjct: 61  LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP--------- 111

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
                   +   D+ Y++TWKA + +  EGL++SIG SNFN+  LER++      PV+NQ
Sbjct: 112 --------VPSQDL-YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQ 162

Query: 590 VECHPYLNQKRLK 628
           +E +P L Q  ++
Sbjct: 163 IELNPMLQQPEMR 175


>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 301

 Score =  130 bits (315), Expect = 2e-29
 Identities = 79/191 (41%), Positives = 109/191 (57%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           K+P V  NNG  +P  G+GT+  K     + V  AI +G+R ID A  YGNEKEVGE I 
Sbjct: 28  KVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGEGIC 86

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
              + G+  RE LFIT+K+     R   VR +L ++L +L   Y+DL LIHWP       
Sbjct: 87  ---RSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP------- 135

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
                   G I+       +TW+ +E  V +G ++SIGVSNFN   L+ LL++A ++PVV
Sbjct: 136 ------VKGHIK-------ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVV 182

Query: 584 NQVECHPYLNQ 616
           NQ+E  PY+ Q
Sbjct: 183 NQIEIEPYMTQ 193


>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinobacteria (class)|Rep: 2,5-didehydrogluconate
           reductase - Arthrobacter sp. (strain FB24)
          Length = 276

 Score =  130 bits (315), Expect = 2e-29
 Identities = 75/189 (39%), Positives = 99/189 (52%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           PV+  N+G  IP  GLGTW     +V  AV +A++ GYRHID A  YGNEK VG  I S 
Sbjct: 5   PVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIRS- 63

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
                + R +LFIT+KL   F   D     L  +L  L + Y+DL LIHWP   ++    
Sbjct: 64  ---SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD---- 116

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
                         +++ TWK  E L  +G V+SIGVSNF    LERL+    V P VNQ
Sbjct: 117 --------------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQ 162

Query: 590 VECHPYLNQ 616
           ++  P + +
Sbjct: 163 IQVSPAITR 171


>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
           Pezizomycotina|Rep: Aldo/keto reductase family proteins
           - Aspergillus oryzae
          Length = 294

 Score =  130 bits (315), Expect = 2e-29
 Identities = 81/211 (38%), Positives = 112/211 (53%), Gaps = 9/211 (4%)
 Frame = +2

Query: 29  SKMAPKIPVVTFNNGETIPVFGLGT---WKSKPG------EVTQAVKDAIDIGYRHIDCA 181
           S   P  P V  N+  +IP+ G GT   W  + G      E+ +A+K AI +GYRH+D A
Sbjct: 3   SNSIPNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGA 62

Query: 182 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLD 361
            VYG E E+G A    IKE  + RE+LF+T+K+         +  A+ ++L  L + Y+D
Sbjct: 63  EVYGTEAELGVA----IKESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVD 115

Query: 362 LYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQ 541
           LYLIH P   K DG L                   W AME + + G  K+IGVSN++   
Sbjct: 116 LYLIHSPFFAKSDGEL----------------QQAWAAMEKVQQAGKAKAIGVSNYHQSH 159

Query: 542 LERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
           LE  L+ A + PV+NQ+E HPYL Q+ L  F
Sbjct: 160 LEATLKTAVIAPVINQIEHHPYLQQEELLRF 190


>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
           reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
           NADH/NADPH dependent indole-3-acetaldehyde reductase
           AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
          Length = 284

 Score =  130 bits (315), Expect = 2e-29
 Identities = 92/212 (43%), Positives = 118/212 (55%), Gaps = 8/212 (3%)
 Frame = +2

Query: 23  IISKMAPKIPVVTFNNGETIPVFGLGT--WKSKPGEVTQ----AVKDAIDIGYRHIDCAY 184
           +I+ M PKIPV         P +G+GT  +K + GE+ +    +VK+A+  G+ HIDCA 
Sbjct: 2   LIAAMGPKIPV---------PAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAE 52

Query: 185 VYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 364
           VYGNE+EVG A+    KE  V R  LFITSK+    H  D +  AL E+L  L   YLDL
Sbjct: 53  VYGNEEEVGVAL----KEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDL 105

Query: 365 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544
           YL+H P  + E           KI  S+      WKAME  +  GLV S+GVSNF    L
Sbjct: 106 YLLHSPIPFYEK----------KIPISE-----GWKAMETALGTGLVHSVGVSNFRIPDL 150

Query: 545 ERLLQHATVKPVVNQVECHP--YLNQKRLKEF 634
           E LL+ +T+ P VNQ+E HP  Y   K L EF
Sbjct: 151 EELLKTSTITPRVNQIEFHPQVYKAAKPLVEF 182


>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
           Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
           putida
          Length = 296

 Score =  130 bits (314), Expect = 3e-29
 Identities = 75/197 (38%), Positives = 105/197 (53%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           MA K P++  NNG  +P  GLG + +   E   A+  AI  GYR ID A  Y NE +VGE
Sbjct: 1   MAGKSPLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGE 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
                I+   V R ++F+T+KL+N  +  +    A  E+L  L + Y+DLYL+HWP    
Sbjct: 61  G----IRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP---- 112

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574
                   D +  IQ        +WKA E ++ +G  ++IGV NF   QL+ L+  + V 
Sbjct: 113 ------TKDWNATIQ--------SWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVV 158

Query: 575 PVVNQVECHPYLNQKRL 625
           P VNQ+E HPY  QK L
Sbjct: 159 PAVNQIELHPYFAQKPL 175


>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
           Aldo-keto reductase - Helicobacter hepaticus
          Length = 292

 Score =  130 bits (313), Expect = 4e-29
 Identities = 75/182 (41%), Positives = 101/182 (55%), Gaps = 1/182 (0%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI-TSKIK 235
           T NNG  IP  GLGTW+     V  AV++A  +GYRHID A  YGNE+ VGEA+  SKIK
Sbjct: 16  TLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVRKSKIK 75

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
                RE+LFITSK+   +        ++  +L  + + ++DL LIH PQ +      F 
Sbjct: 76  -----REELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS----FR 126

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                K      + V+ + A+E   K G V+SIGVSNF  K LE +L++   KP  NQ+ 
Sbjct: 127 KGDYFK------ENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQIL 180

Query: 596 CH 601
           CH
Sbjct: 181 CH 182


>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 287

 Score =  130 bits (313), Expect = 4e-29
 Identities = 66/191 (34%), Positives = 116/191 (60%), Gaps = 2/191 (1%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           NG+ IP   LGT+++K  ++  AV +A+ +GYR  D A  Y NEK++G A+ + +    +
Sbjct: 6   NGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRHNI 65

Query: 248 TREDLFITSKL--WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
             ED+++TSK+  +++ +  +L+R  + E+L+ L+ +YLDL L+H+P+         P D
Sbjct: 66  CSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR---------PLD 116

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
                + + +   DTW A+E L  EG ++SIGVSN+    +E +  + T++P VNQ+E H
Sbjct: 117 TEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIEYH 176

Query: 602 PYLNQKRLKEF 634
           P+  +K L+ +
Sbjct: 177 PHFQRKVLRAY 187


>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
           AkrI - Butyrivibrio fibrisolvens
          Length = 172

 Score =  129 bits (312), Expect = 5e-29
 Identities = 72/178 (40%), Positives = 99/178 (55%), Gaps = 1/178 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           +  NNG  IP+FG GT+K K   E   +V+ A+  GYRHID A  Y NEK V  AI   +
Sbjct: 8   IKLNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFM 67

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
           +E    RED+F+TSK W T    D    A ++T++ + + YLDLYL+HWP +Y  D    
Sbjct: 68  EESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWE 127

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
            T++             TWKAM  + K G VK+IGVSNF +  L+ ++    V P V+
Sbjct: 128 NTNR------------QTWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID-MEVTPAVD 172


>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
           Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
           protein - Erythrobacter sp. SD-21
          Length = 272

 Score =  129 bits (311), Expect = 6e-29
 Identities = 71/194 (36%), Positives = 103/194 (53%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P +  N+G  IP  G GTW+ +  +  QAV  AID+GY  ID A +YGNEK VG      
Sbjct: 5   PTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG------ 58

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
             +GV    D+F+ +K+WN     D    A ++ L+ L  +++D+ LIHWP   K+    
Sbjct: 59  --KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD---- 112

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
                          +VDTWKA+  L   G  KSIGVSNF  + L+R++    V P +NQ
Sbjct: 113 --------------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQ 158

Query: 590 VECHPYLNQKRLKE 631
           +E HP   Q+ +++
Sbjct: 159 IELHPSFQQRDMRK 172


>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
           Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 281

 Score =  129 bits (311), Expect = 6e-29
 Identities = 79/193 (40%), Positives = 102/193 (52%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP +T NNG  IP  G G ++  P E  + V+DA++ GYRHID A  Y NE  VG AI++
Sbjct: 9   IPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAISA 68

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
                 + RED+FIT+KL N          A Q +   L V+++DLYLIHWP        
Sbjct: 69  ----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHWPVP------ 116

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
                       S   Y + WKAME L     +++IGVSNF  + L+ LL  A V P VN
Sbjct: 117 ------------SQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVN 164

Query: 587 QVECHPYLNQKRL 625
           QVE HP   Q+ L
Sbjct: 165 QVEIHPTFQQQEL 177


>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
           ENSANGP00000029046 - Anopheles gambiae str. PEST
          Length = 331

 Score =  129 bits (311), Expect = 6e-29
 Identities = 76/194 (39%), Positives = 109/194 (56%), Gaps = 4/194 (2%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           N G  IP+ G GT++    E+   V D A++ GYRHID A VY NE+ +G A+ + + + 
Sbjct: 37  NTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPKY 96

Query: 242 VVTREDLFITSKLWNTFHRPD-LVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
            + RED+FITSKL +   + +  V   ++++L NL   YLDLYLIHWP    + G     
Sbjct: 97  NLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWKWL 156

Query: 419 DQSGKIQFSDVDY-VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVNQV 592
                    +V Y   +W A+  L +EG ++SIGVSN+  K L+ +L     + P VNQV
Sbjct: 157 FGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVNQV 216

Query: 593 ECHPYLNQKRLKEF 634
           E HPY  Q  L E+
Sbjct: 217 EWHPYYYQPELLEY 230


>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
           coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
           coagulans 36D1
          Length = 273

 Score =  128 bits (310), Expect = 8e-29
 Identities = 69/176 (39%), Positives = 101/176 (57%), Gaps = 1/176 (0%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NG  IP  GLGTW+   GE T  AV  A+  GYRHID AY Y NE+ VG+A+    ++  
Sbjct: 12  NGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGKAV----RDSG 67

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + R D+F+TSKL       D       ET+ N  ++ LDLYLIH P  + E G+ +  + 
Sbjct: 68  IDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKGADYTKEN 127

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                      ++ WKAME + + G  ++IGVSNF+   L+ ++++A +KP+VNQ+
Sbjct: 128 -----------IEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172


>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
           Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
           - Mycobacterium sp. (strain KMS)
          Length = 283

 Score =  127 bits (307), Expect = 2e-28
 Identities = 71/198 (35%), Positives = 108/198 (54%)
 Frame = +2

Query: 38  APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217
           A  IP V+ N+G +IPV GLG  +    E  ++V  A++ GYR ID A VYGNE  VG A
Sbjct: 8   AAGIPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRA 67

Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397
           + +      + RE++++T+KL          + A + +L+ L + Y+DLYLIHWP     
Sbjct: 68  VNAS----GIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAG--- 120

Query: 398 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577
                     GK       Y+D+W  +    ++G+ +SIGV NFN++ L  ++  +   P
Sbjct: 121 --------DHGK-------YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTP 165

Query: 578 VVNQVECHPYLNQKRLKE 631
            +NQ+E HP LNQ  L+E
Sbjct: 166 AINQIELHPLLNQAELRE 183


>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=2; Tetrahymena thermophila SB210|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 332

 Score =  127 bits (307), Expect = 2e-28
 Identities = 74/191 (38%), Positives = 112/191 (58%), Gaps = 1/191 (0%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           NNG+ +P+ GLGT+  +   E+T  ++ A+D GYRHID A  Y NE  +GE++ +  KEG
Sbjct: 11  NNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKEG 70

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
             +R+DLFI SK++   ++   +  +++++L  L + Y+DLY +H+P  +          
Sbjct: 71  KYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGF---------- 118

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
            S K +F  +     W  +E   + GL KSIGVSNFN   L  LL +A VKPV NQVE  
Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVS 178

Query: 602 PYLNQKRLKEF 634
            ++ QK L +F
Sbjct: 179 VFIQQKNLIKF 189


>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=3; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 299

 Score =  127 bits (306), Expect = 3e-28
 Identities = 73/195 (37%), Positives = 108/195 (55%), Gaps = 1/195 (0%)
 Frame = +2

Query: 53  VVTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           V+T +NG+ +P FGLG+ + +   EVT  ++ A+D+GYRHID A +Y NE+ +G A+ + 
Sbjct: 9   VITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTI 68

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
             EG   RED+F+ +K      +       ++E L  L V Y+DL LIH P A       
Sbjct: 69  FGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLA------- 119

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
            P+D   +     V  +  W   E +   GL K +GVSNFN + +  LL +  +KP+VNQ
Sbjct: 120 APSDDYQQWNHKPVHQI--WAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQ 177

Query: 590 VECHPYLNQKRLKEF 634
           +E H +  QK L EF
Sbjct: 178 IELHVFNQQKNLVEF 192


>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 275

 Score =  127 bits (306), Expect = 3e-28
 Identities = 75/192 (39%), Positives = 104/192 (54%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T ++G  IP FGLG +        QAV  A++ GYR ID A  Y NEK VGEA    ++E
Sbjct: 8   TLSDGYKIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA----LRE 63

Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
             V R ++++ +K+++T H  +    A   +L  L V Y+DLYLIH+P            
Sbjct: 64  SAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFP------------ 111

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
                        V +W+AM  L  +GL +SIGVSNFN   LE L +H+ + PVVNQ+E 
Sbjct: 112 --------VPAGVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEV 163

Query: 599 HPYLNQKRLKEF 634
           HPYL  + L +F
Sbjct: 164 HPYLQMEELVDF 175


>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
           Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
           Lactobacillus acidophilus
          Length = 271

 Score =  126 bits (305), Expect = 3e-28
 Identities = 70/182 (38%), Positives = 101/182 (55%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           V  NNGE IP   LGTW     EV + V+ A++IGYR  D A  YGNE  VG+ I +   
Sbjct: 7   VILNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIWN--- 63

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
              + R D+F+T+KL       +  + A+   LD   ++Y+DL LIH PQ + E      
Sbjct: 64  -SDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIE------ 116

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
            +++    F     ++ W+AME  VK G V+SIGVSNF  + +E ++ + T+ P VNQ+E
Sbjct: 117 VNRTNDRHFK--GNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIE 174

Query: 596 CH 601
            H
Sbjct: 175 VH 176


>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           oxidoreductase - Corynebacterium jeikeium (strain K411)
          Length = 285

 Score =  126 bits (305), Expect = 3e-28
 Identities = 73/190 (38%), Positives = 102/190 (53%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           +P +  N+G+T P  GLG W+    +   +V+ AI+ GYRHID A +YGNE+ VG A+  
Sbjct: 8   VPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGRAVAD 67

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
            +K G V RE+LFIT+KLWN        + A  E+   L + Y+DLYL+HWP        
Sbjct: 68  AVKAGDVQREELFITTKLWNADQA--CGKEAFAESQKKLGMDYVDLYLLHWP-------- 117

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
             P   S         +V  + +M  + + G   SIGV NF  + L+ L Q A   P VN
Sbjct: 118 -CPQADS---------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQ-AGHTPAVN 166

Query: 587 QVECHPYLNQ 616
           Q+E HP  +Q
Sbjct: 167 QIEIHPGFSQ 176


>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
           Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 282

 Score =  126 bits (305), Expect = 3e-28
 Identities = 77/205 (37%), Positives = 118/205 (57%), Gaps = 5/205 (2%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           M PK      +NG  IP   LGT+     +  + V + +  GYRH D A +YGNEKEVG+
Sbjct: 1   MVPKF--YKLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGD 58

Query: 215 AITSKIKE--GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLN-VQYLDLYLIHWPQ 385
            I   + E  G   RE++F T+KLWN+ +     + A+++ L+ ++ +QY+DL LIH P 
Sbjct: 59  GIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL 118

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
               +GS        K++      ++TW+AM+  V EGLVKSIGVSN+  K ++ LL   
Sbjct: 119 ----EGS--------KLR------LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWP 160

Query: 566 TV--KPVVNQVECHPYLNQKRLKEF 634
            +  KPVVNQ+E  P++ ++ L ++
Sbjct: 161 ELKHKPVVNQIEISPWIMRQELADY 185


>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 287

 Score =  126 bits (304), Expect = 4e-28
 Identities = 70/186 (37%), Positives = 106/186 (56%), Gaps = 1/186 (0%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDA-IDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256
           +P+ G+GTW+ +  E+ + V DA    GYR ID A VY NE ++G  +   +    + RE
Sbjct: 11  MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRE 70

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436
           D++ITSKL  +       R +++E+L NL V+YLDL LIHWP      GS   ++     
Sbjct: 71  DIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP------GSSLKSENPANK 124

Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616
           +      V++W  M  ++ EG ++S+GVSNF    LE L + + V P VNQVE HP+ +Q
Sbjct: 125 KLR----VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQ 180

Query: 617 KRLKEF 634
             L ++
Sbjct: 181 DDLVKY 186


>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 288

 Score =  126 bits (303), Expect = 6e-28
 Identities = 76/197 (38%), Positives = 104/197 (52%), Gaps = 1/197 (0%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 220
           K P +T N+G  IP  G GT++    G   QAVK+A+ IGYRHID A  Y NE EVG+A 
Sbjct: 3   KTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQA- 61

Query: 221 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 400
              IK+  + R+ +++TSKLW   +  D    A+  +L  L + Y+DLYLIH P      
Sbjct: 62  ---IKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP------ 112

Query: 401 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580
                        + DV     W+AME   K G +KSIGVSN      ++ +      P 
Sbjct: 113 -------------YGDVP--GAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPA 157

Query: 581 VNQVECHPYLNQKRLKE 631
           VNQVE +PY  Q+ L++
Sbjct: 158 VNQVEFNPYFQQQPLRQ 174


>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=2; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
          Length = 273

 Score =  126 bits (303), Expect = 6e-28
 Identities = 70/193 (36%), Positives = 106/193 (54%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +T NN   IP+FG GT++  P +  QAV  A + GYR ID A  Y NE++VGEA    +K
Sbjct: 4   LTLNNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA----VK 59

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
              + R+++FIT+K     +    +   L E+L  + + Y DL LIHWP  +        
Sbjct: 60  ASGLNRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD------- 110

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                         +DTW A+E   K G  ++IG+SNFNS+Q   L+  ++V+P+V+Q+E
Sbjct: 111 --------------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIE 156

Query: 596 CHPYLNQKRLKEF 634
            H +L Q ++ EF
Sbjct: 157 THLFLQQWKMHEF 169


>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
           aldo/keto reductase family - Lactococcus lactis subsp.
           cremoris (strain MG1363)
          Length = 281

 Score =  126 bits (303), Expect = 6e-28
 Identities = 80/194 (41%), Positives = 110/194 (56%), Gaps = 1/194 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           +  N+G  IP FGLG ++   GE T+ AVK+A+ +GYRHID A+ Y NE+ VG AI S  
Sbjct: 5   IVLNDGNIIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS-- 62

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
             G+   E ++ITSKLW + +  D    A++  L+ LN++ +DL L+H            
Sbjct: 63  -SGIPISE-IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLH------------ 106

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
              Q G       +Y   W A+E  VK G VKSIG+SNF+ ++L  L   A +KP   QV
Sbjct: 107 --QQVG-------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQV 157

Query: 593 ECHPYLNQKRLKEF 634
           E HPY  QK L+EF
Sbjct: 158 ETHPYHQQKELQEF 171


>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_5, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 247

 Score =  126 bits (303), Expect = 6e-28
 Identities = 83/196 (42%), Positives = 110/196 (56%), Gaps = 14/196 (7%)
 Frame = +2

Query: 47  IPVVTFNN-GETIPVFGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           IP +T  + G+ IP+ G+ T  +   P E +  ++  AI++GYRH DC   Y +EK +GE
Sbjct: 4   IPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGE 63

Query: 215 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETL---------DNLNVQYLDL 364
           AI   +K G++ +R++LFITSKLW +    D V  ALQ TL          NL + YLDL
Sbjct: 64  AIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLDL 123

Query: 365 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544
           YLIHW      DG L             +D    WKAME   K  L K+IGVSNF+  +L
Sbjct: 124 YLIHW-----SDGHL------------PIDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKL 166

Query: 545 ERLLQHATVKPVVNQV 592
           E LLQ A++ P VNQV
Sbjct: 167 EELLQTASILPAVNQV 182


>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Escherichia coli (strain UTI89 / UPEC)
          Length = 294

 Score =  125 bits (302), Expect = 8e-28
 Identities = 75/186 (40%), Positives = 101/186 (54%), Gaps = 2/186 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           +N   +P+ G G ++    +V  Q+V +AI  GYR ID A VYGNE  VGEA+   I EG
Sbjct: 12  SNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEG 71

Query: 242 VVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
           + TRE+LFITSKLW       D+    ++ +L    ++Y DLYL+H  QA +        
Sbjct: 72  LCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH--QAMR-------- 121

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
                      DY   W+A+E   +EG +K+IGVSNF    L    +   VKP+VNQVE 
Sbjct: 122 -----------DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVEL 170

Query: 599 HPYLNQ 616
           HPY  Q
Sbjct: 171 HPYFAQ 176


>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
           Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
          Length = 308

 Score =  124 bits (299), Expect = 2e-27
 Identities = 68/187 (36%), Positives = 106/187 (56%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           +G  +P+ GLG +++ P E T AV++A+ +GYRHID A  YGNE+EVGE     I+   +
Sbjct: 25  SGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEG----IRRAGI 80

Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 427
            R+++FI +K+W + +  D    A  ++   L V  +DL L+H P     D +L      
Sbjct: 81  ARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRTL------ 134

Query: 428 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607
                        ++A+E L+ +G V++IGVSNF  + L RLL   ++ P VNQ+E HPY
Sbjct: 135 -----------GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPY 183

Query: 608 LNQKRLK 628
             Q+ L+
Sbjct: 184 FQQRALQ 190


>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
           Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 349

 Score =  124 bits (299), Expect = 2e-27
 Identities = 83/216 (38%), Positives = 111/216 (51%), Gaps = 27/216 (12%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           +G  IP  GLGTW+S        V   ++ GYRHID A+ YG+++EVG+ I   +  G+ 
Sbjct: 20  SGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAGL- 78

Query: 248 TREDLFIT----------------SKLWN-----------TFHRPDLVRGALQETLDNLN 346
            R DLF+T                S L N           T   P+ VR ALQ TL  L 
Sbjct: 79  ERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKELQ 138

Query: 347 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 526
           ++YLDLYLIHWP   +E  S  P  ++G +   D D    W+ ME L K+ LV++IGV N
Sbjct: 139 LEYLDLYLIHWPIRLREGASKPP--KAGDVL--DFDMEGVWREMENLSKDSLVRNIGVCN 194

Query: 527 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
           F   +L +LL  A + P V Q+E HP     R+ EF
Sbjct: 195 FTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEF 230


>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
           n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
           Apis mellifera
          Length = 292

 Score =  124 bits (298), Expect = 2e-27
 Identities = 70/196 (35%), Positives = 112/196 (57%), Gaps = 3/196 (1%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           V  ++G  +P+ G GT+K +  E V Q V +++++G+R ID A  Y NE+++G A+ + +
Sbjct: 8   VCLSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLL 67

Query: 233 KEGVVTREDLFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
            +  + R D+FIT+KL  + +  P  +   +Q++L   N  Y+DLYLIHWP A +     
Sbjct: 68  PKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATR----- 122

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPVVN 586
            P   +            TW  +  L K+G ++SIGVSNF  K L+ LLQ+   + P VN
Sbjct: 123 IPETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVN 178

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HP+  Q+ L ++
Sbjct: 179 QVELHPHYRQEELIKY 194


>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Acinetobacter sp. (strain ADP1)
          Length = 297

 Score =  124 bits (298), Expect = 2e-27
 Identities = 71/196 (36%), Positives = 104/196 (53%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP +  ++G +IP  G GT+  K  +    +  A+  GYR +D A+ Y NE  VG A+  
Sbjct: 22  IPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAAV-- 79

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
             ++  + R+++FITSKL    H  D     ++E+L  +   YLDLYLIHW         
Sbjct: 80  --RQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHW--------- 128

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
             P  Q G        Y++ W+A+    K+G ++SIGVSNF  K +E L +   V PV+N
Sbjct: 129 --PNPQQGL-------YIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVIN 179

Query: 587 QVECHPYLNQKRLKEF 634
           QVE HPY NQ   + +
Sbjct: 180 QVELHPYFNQAEQRAY 195


>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 263

 Score =  124 bits (298), Expect = 2e-27
 Identities = 76/186 (40%), Positives = 102/186 (54%), Gaps = 1/186 (0%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256
           +P+ GLG +K+    E   A+  A+  GYR +D A  Y NE+ VG  I    K GV  R+
Sbjct: 1   MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIA---KCGV-PRK 56

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436
           DLFIT+K+WN   R   V GA Q +LD L + Y+DLYLIHWP      G           
Sbjct: 57  DLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP----VPGC---------- 102

Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616
                 +++TWK ME +++ G   SIGVSNF  + LE L + + + P VNQ+ECHP    
Sbjct: 103 ------FLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYP 156

Query: 617 KRLKEF 634
           K L E+
Sbjct: 157 KELIEY 162


>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
           Phytophthora infestans|Rep: Aldo-keto reductase,
           putative - Phytophthora infestans (Potato late blight
           fungus)
          Length = 255

 Score =  124 bits (298), Expect = 2e-27
 Identities = 71/201 (35%), Positives = 112/201 (55%), Gaps = 1/201 (0%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211
           M+  +P     +G  IP+ GLG ++S+PG E   A+  ++ +GYRHID A +YGNE++VG
Sbjct: 1   MSVNVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVG 60

Query: 212 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391
            A    +++  + RE++F+T+KL+ T         A + + D L + Y+ LYL+H P   
Sbjct: 61  RA----VRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPP 116

Query: 392 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571
           KE                     DTW+A+E L ++  ++ IGVSNFN   L  L + A +
Sbjct: 117 KE-------------------RADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHI 157

Query: 572 KPVVNQVECHPYLNQKRLKEF 634
           KP VNQVE HP++ ++ L  +
Sbjct: 158 KPAVNQVELHPWMMRQSLVNY 178


>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
           Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
           alexandrii HTCC2633
          Length = 275

 Score =  123 bits (296), Expect = 4e-27
 Identities = 69/183 (37%), Positives = 96/183 (52%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           NG  IP  G GTW+ +  +  + V  A+  GYRHID A +YGNE  VG+      K+  V
Sbjct: 8   NGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG----WKQSGV 63

Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 427
            RED F+T+K+W    R   ++ +++E+LD L   Y+DL L+HWP               
Sbjct: 64  KREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP--------------- 108

Query: 428 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607
                 +V   +T KAM  + + G V+ IGVSNF    L+    H+    V NQVE HPY
Sbjct: 109 ----VPEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPY 164

Query: 608 LNQ 616
           L+Q
Sbjct: 165 LDQ 167


>UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1;
           Aspergillus fumigatus|Rep: Aldehyde reductase, putative
           - Aspergillus fumigatus (Sartorya fumigata)
          Length = 350

 Score =  123 bits (296), Expect = 4e-27
 Identities = 72/164 (43%), Positives = 94/164 (57%), Gaps = 7/164 (4%)
 Frame = +2

Query: 155 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETL 334
           +GYRHID A V  NE EVG       K+  V RE +F+TSKLWNT H P  V  AL +T+
Sbjct: 72  VGYRHIDSAAVGLNEAEVGRGW----KKLGVPREGIFLTSKLWNTHHHPSHVEEALDKTV 127

Query: 335 DNLNVQYLDLYLI----HWPQAYKEDGSLFPTDQSGKIQFS--DVDYVDTWKAMEPLVKE 496
            +L   YLDLYL+    H    Y+      P  + G  +F   D+   DTW A E LV  
Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184

Query: 497 GLVKSIGVSN-FNSKQLERLLQHATVKPVVNQVECHPYLNQKRL 625
           G ++S+GVSN F  +++E LL  A + P VNQ+E HPYL Q ++
Sbjct: 185 GKIRSLGVSNLFTIEKMEELLNTADIPPAVNQIEAHPYLLQPKI 228


>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 286

 Score =  123 bits (296), Expect = 4e-27
 Identities = 79/199 (39%), Positives = 111/199 (55%), Gaps = 4/199 (2%)
 Frame = +2

Query: 50  PVVTFN--NGETIPVFGLGTWKSKPG--EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217
           P  +F   NG T+P  GLGT++   G  +V   VK AI  GYRHID A  YGNE+ +G+A
Sbjct: 4   PTASFRLVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDA 63

Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397
           I    KE  ++R++L   ++ W   H P  V  AL  +L+ L ++Y+       P AY  
Sbjct: 64  I----KESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV-------PHAYLP 106

Query: 398 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577
             +    ++S K       Y +TW+AME LV  G  K+IG+SNFN  + +R+L+ A ++P
Sbjct: 107 GPNNVDYERSRK-------YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRP 159

Query: 578 VVNQVECHPYLNQKRLKEF 634
            VNQVE HPY  Q  L  F
Sbjct: 160 AVNQVEAHPYFPQHELLAF 178


>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
           Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  122 bits (294), Expect = 7e-27
 Identities = 79/205 (38%), Positives = 111/205 (54%), Gaps = 1/205 (0%)
 Frame = +2

Query: 20  KIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGN 196
           K  S  A   P V  +NG  IP+ GLGT     G   +AV  A+ + G RHID A  YG 
Sbjct: 4   KPTSCTALSCPAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGC 62

Query: 197 EKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIH 376
           E+ +G+A+T    E  V RE+L++T+KLW   +     + A +++   L V YLDLYL+H
Sbjct: 63  EEALGKAVT----ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMH 118

Query: 377 WPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 556
           WP       S+ P   S +++      ++TW+A+E L  EGL ++IGVSNF    L  L 
Sbjct: 119 WPD------SMVPGRSSQEVR------LETWRALEELYDEGLCRAIGVSNFLIPHLNELK 166

Query: 557 QHATVKPVVNQVECHPYLNQKRLKE 631
               + P VNQVE HP+    +L E
Sbjct: 167 DSGGIVPHVNQVEFHPFQQPMKLVE 191


>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 282

 Score =  122 bits (294), Expect = 7e-27
 Identities = 70/190 (36%), Positives = 104/190 (54%), Gaps = 1/190 (0%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NG  IP    GTW+   GE T QAV+ A+  GYRHID A  Y NE  VG+AI    ++  
Sbjct: 12  NGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAI----RDSG 67

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + RE +F+T+KL                +L NL + Y+DLYL+H P         +P  Q
Sbjct: 68  IPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPWGQ 118

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
            G++   D   +D W+AME + + G  K+IGVSNF  + L+ +L  AT+ P+VNQ++ + 
Sbjct: 119 VGRVY--DEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYL 176

Query: 605 YLNQKRLKEF 634
              + ++ +F
Sbjct: 177 GFTEPKITKF 186


>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
           Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 287

 Score =  122 bits (293), Expect = 1e-26
 Identities = 73/196 (37%), Positives = 109/196 (55%), Gaps = 1/196 (0%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           +P V   +G  +P+ GLGT+K +  E + Q+V  A+  GYR  D A VYGNE  +G+ + 
Sbjct: 3   VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
             + +  + RED+FI SKL  + H      G L+ +L+ L+ +Y+DLYLIHWP     +G
Sbjct: 63  ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGM---EG 118

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
            L P D     + S+     +W  +E     G  K+IGVSN+ +K +  LL    V P V
Sbjct: 119 -LDPEDS----RHSEYR-AQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAV 172

Query: 584 NQVECHPYLNQKRLKE 631
            Q+EC P L Q+ L++
Sbjct: 173 LQIECQPKLIQRELRD 188


>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 324

 Score =  121 bits (292), Expect = 1e-26
 Identities = 78/199 (39%), Positives = 106/199 (53%), Gaps = 9/199 (4%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKP-----GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           N    IP  GLGT++  P     G V  +V  A+ IGYRHID A  YG    V   I + 
Sbjct: 11  NTSIRIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAA 69

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           I+   V RED+F+ +KL N FH P+ V   +  +L NL + Y+       P AY +  + 
Sbjct: 70  IRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTKGENY 122

Query: 410 FPTDQSGKIQFSDVD----YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577
               +       D++    +  TWKAME LV +G  K IGVSNF++ +L+RLL    + P
Sbjct: 123 STVRKPDGKPVVDIELSRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFP 182

Query: 578 VVNQVECHPYLNQKRLKEF 634
           VVNQVE +PY  QK+L  F
Sbjct: 183 VVNQVELNPYFPQKQLLRF 201


>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
           Lin2848 protein - Listeria innocua
          Length = 280

 Score =  119 bits (287), Expect = 5e-26
 Identities = 69/191 (36%), Positives = 105/191 (54%), Gaps = 1/191 (0%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241
           NNG  +P  G G +K +    +  A++ A+D+GYR  D A  Y NEKE+G+   S     
Sbjct: 12  NNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS---- 67

Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
            + R++ F+T+K+WNT    D    A +++   L +  +DLYL+HWP   K+D       
Sbjct: 68  GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------- 117

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
                      + +TW+A+E L  EGLV++IGVSNF +  L+RL   A V PVV+Q+E H
Sbjct: 118 ----------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETH 167

Query: 602 PYLNQKRLKEF 634
           P+   + L  +
Sbjct: 168 PHFPNQLLHRY 178


>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Lactobacillus acidophilus
          Length = 278

 Score =  119 bits (287), Expect = 5e-26
 Identities = 70/194 (36%), Positives = 109/194 (56%), Gaps = 1/194 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           VT NNG  +P  G G ++     +  Q V+D +++GYR +D A +YGNE+ VG+AI    
Sbjct: 5   VTLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI---- 60

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
           K   V RED+FITSK+W   +  D    A  +++  L + Y+DLYLIH P  Y       
Sbjct: 61  KHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP--YN------ 112

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                        DY  TW+A+E L +EG +++IGVS+F +++L  L+    VKP VNQ+
Sbjct: 113 -------------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQI 159

Query: 593 ECHPYLNQKRLKEF 634
           E + +  + + +++
Sbjct: 160 ETNVWNQEWKSQQY 173


>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
           Filobasidiella neoformans|Rep: Oxidoreductase, putative
           - Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 321

 Score =  119 bits (286), Expect = 7e-26
 Identities = 86/207 (41%), Positives = 110/207 (53%), Gaps = 22/207 (10%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCA---YVYGNEKEVGEAIT 223
           +T N+G  IP    GTWK  P EVT   V  AID+G+ HID A    VY NE+EVG+A  
Sbjct: 6   ITLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEVGQA-- 62

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
             IKE  ++R  L++T+K W+        R ++ E+L+ L ++YLDLYLIH PQ  K   
Sbjct: 63  --IKESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQVTKG-- 116

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS------------------NF 529
                           D    WK +E L KEG  KSIGVS                  +F
Sbjct: 117 ----------------DIKGAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSDVWDSF 160

Query: 530 NSKQLERLLQHATVKPVVNQVECHPYL 610
           N +QL+ LL HATVKPVVNQ+  HPY+
Sbjct: 161 NKEQLQELLAHATVKPVVNQILLHPYV 187


>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
           reductase family - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 279

 Score =  118 bits (285), Expect = 9e-26
 Identities = 72/200 (36%), Positives = 112/200 (56%), Gaps = 2/200 (1%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETI-PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211
           M+  +P V   +G+ + P  G GTW+ + G     V+ A++IGYRHID A +YGNE++VG
Sbjct: 1   MSKLVPAV--RSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVG 58

Query: 212 EAITSKIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388
            A    I+   V R+++F+T+K+W + F   DL R A +++L+ L V  +DL L+HWP+ 
Sbjct: 59  AA----IRNSGVKRDEIFLTTKVWIDQFADGDLQRSA-EKSLEKLGVDQVDLLLLHWPK- 112

Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
                              +V   +T KA+  +  +G  ++IG+SNF S QLE   + + 
Sbjct: 113 ------------------PEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSE 154

Query: 569 VKPVVNQVECHPYLNQKRLK 628
                +QVE HPYL+ K LK
Sbjct: 155 APIATDQVEYHPYLSLKTLK 174


>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 282

 Score =  118 bits (285), Expect = 9e-26
 Identities = 70/191 (36%), Positives = 101/191 (52%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +T NNG TIP  GLGT+  +P +   AV  A+D  Y  ID A VY NE+ VG  + +  K
Sbjct: 4   ITLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK 63

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
                R+++F+ +KLW +F        A++ETL+ L   Y+DL ++H P           
Sbjct: 64  ----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG--------- 107

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                       D V  ++ +E   KEG +++IG+SNF+  Q +R+L    V P +NQVE
Sbjct: 108 ------------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVE 155

Query: 596 CHPYLNQKRLK 628
           CHPY  Q  LK
Sbjct: 156 CHPYFPQTELK 166


>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
           eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 176

 Score =  118 bits (283), Expect = 2e-25
 Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 8/174 (4%)
 Frame = +2

Query: 47  IPVVTFNNG----ETIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205
           +P +   +G     ++PV G GT  S   +P  + + V +AI +GYRH D +  Y  E+ 
Sbjct: 6   VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEP 65

Query: 206 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382
           +GEA+   +  G+V +R + F+T+KLW       LV  A++ +L NL + YLDLY+IHWP
Sbjct: 66  IGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWP 125

Query: 383 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544
            + K     FP D+     F  +D+   W  ME   + GL K IGVSNF+ K+L
Sbjct: 126 VSSKPGKYKFPIDED---DFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176


>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
           cryohalolentis K5|Rep: Aldo/keto reductase -
           Psychrobacter cryohalolentis (strain K5)
          Length = 282

 Score =  117 bits (282), Expect = 2e-25
 Identities = 70/187 (37%), Positives = 101/187 (54%), Gaps = 2/187 (1%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           IPV GLGTW+S   +    V   + +GY HID A  YGNE EVG+     IK+  V R+ 
Sbjct: 16  IPVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKG----IKQSGVARDK 71

Query: 260 LFITSKLW--NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 433
            F+T+K++  +    P+ +  A + +L+NL+  Y+DL L+HWP                 
Sbjct: 72  FFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD---------------- 115

Query: 434 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 613
                V   +T  A+  L K+GL ++IGVSNFN   +    ++A V  VVNQVE HP++ 
Sbjct: 116 ---DRVPLSETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPFIK 172

Query: 614 QKRLKEF 634
           QK L+ F
Sbjct: 173 QKTLQTF 179


>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
           n=1; Haloarcula marismortui|Rep: Oxidoreductase
           aldo/keto reductase family - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 274

 Score =  117 bits (281), Expect = 3e-25
 Identities = 68/188 (36%), Positives = 103/188 (54%)
 Frame = +2

Query: 71  GETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250
           G ++P  GLGTW+       + V+ A+ +GYRHID A  YGNE++VG  + +      V 
Sbjct: 8   GTSVPALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA----AAVD 63

Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430
           RED+F+T+KL  +      VR + +E+L+ L   YLDL LIHWP           T    
Sbjct: 64  REDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWPN----------TPWMA 113

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610
            +        +T  AM  +V+EGLV+ IGVSNF+   L+R    ++     +QV+ HPY 
Sbjct: 114 SLS-------ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYW 166

Query: 611 NQKRLKEF 634
           +Q++L ++
Sbjct: 167 DQRKLLDY 174


>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
           n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase B - Corynebacterium sp. (strain SHS752001)
          Length = 277

 Score =  117 bits (281), Expect = 3e-25
 Identities = 72/198 (36%), Positives = 100/198 (50%)
 Frame = +2

Query: 41  PKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 220
           P IP ++ N+G      GLGT+  +  E   A+  AID GYR +D A  Y NE EVG A 
Sbjct: 2   PNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA- 60

Query: 221 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 400
              ++   V R++L + SK+    H       +++ +LD L +  +DL LIHW       
Sbjct: 61  ---VRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHW------- 110

Query: 401 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580
               P    G+       ++DTW+ M    + GLV+SIGVSNF    L+ L+    V P 
Sbjct: 111 ----PNPSVGR-------WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPA 159

Query: 581 VNQVECHPYLNQKRLKEF 634
           VNQVE HPY  Q  L+ F
Sbjct: 160 VNQVELHPYFPQAALRAF 177


>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
           pacificus|Rep: Aldose reductase - Pristionchus pacificus
          Length = 293

 Score =  116 bits (280), Expect = 4e-25
 Identities = 63/188 (33%), Positives = 101/188 (53%), Gaps = 1/188 (0%)
 Frame = +2

Query: 74  ETIPVFGLGTWKSKPGEV-TQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250
           + +P+ G+GT++ +   V T  + +A  +GYR ID A +Y NE  +G  +   +++  + 
Sbjct: 14  DRMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLK 73

Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430
           RED+FITSK+            ++ ++L +L   Y+DL LIHWP       S   ++   
Sbjct: 74  REDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGT-----SRLKSNHKD 128

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610
             +F    YV+    +E L+ EG ++SIGVSN+  K LE LL    + P +NQ ECHP+ 
Sbjct: 129 NAKFRAETYVE----LETLMDEGKIRSIGVSNYEIKHLETLLAECRILPAINQCECHPHF 184

Query: 611 NQKRLKEF 634
               L E+
Sbjct: 185 RNSELAEY 192


>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 288

 Score =  116 bits (278), Expect = 6e-25
 Identities = 70/194 (36%), Positives = 102/194 (52%), Gaps = 1/194 (0%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           P V  NN   +P+ GLGT++ +  E T  AV  A+  GYR  D A VY NE  +G A+  
Sbjct: 6   PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
            + +  ++RED+FITSKL     +    R   Q++L+ L + Y+DLYLIHWP        
Sbjct: 66  LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQG---- 120

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
             P       +    +   +W+ +E    EG  ++IGVSN+  + ++ LL+   V P V 
Sbjct: 121 -LPVGDKRNPE----NRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVL 175

Query: 587 QVECHPYLNQKRLK 628
           QVE HP L Q  L+
Sbjct: 176 QVEFHPKLLQNDLR 189


>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
           Propionibacterium freudenreichii subsp. shermanii|Rep:
           Putative aldo-keto reductase - Propionibacterium
           freudenreichii subsp. shermanii
          Length = 280

 Score =  116 bits (278), Expect = 6e-25
 Identities = 68/195 (34%), Positives = 105/195 (53%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P V  + G  +P+ G+GTW  K  E   AV  AI+ GYR +D A  YGNE+ VG+A    
Sbjct: 9   PTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKA---- 64

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           ++E    R ++F+T+K    +H    V  AL+ +L+ L + Y+DL+L+HWP     +GS 
Sbjct: 65  VREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM--PGEGS- 121

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
                          YVD ++ M  L ++GL K+IGVSNF    L+ L+    + P VNQ
Sbjct: 122 ---------------YVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQ 165

Query: 590 VECHPYLNQKRLKEF 634
           ++  P   +  +++F
Sbjct: 166 IQLDPSRPRLEVRDF 180


>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 305

 Score =  116 bits (278), Expect = 6e-25
 Identities = 72/193 (37%), Positives = 103/193 (53%), Gaps = 8/193 (4%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI--KEGV--- 244
           +P+ G+GT+K    ++   +K  ++ GYR ID A +Y NE+ +G+ +   +   +G+   
Sbjct: 27  MPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGK 84

Query: 245 -VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
            + REDLFITSK        +    A + +L  L + YLD YLIHWP     DGS    D
Sbjct: 85  KIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGS----D 140

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ--HATVKPVVNQVE 595
               IQ        TW+A+E L ++  V+SIGVSN+    L  LL   +  +KP +NQVE
Sbjct: 141 SGNSIQ-----RAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVE 195

Query: 596 CHPYLNQKRLKEF 634
            HP   QK L EF
Sbjct: 196 FHPLNFQKDLLEF 208


>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 302

 Score =  116 bits (278), Expect = 6e-25
 Identities = 75/198 (37%), Positives = 103/198 (52%), Gaps = 8/198 (4%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGT---WKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEK 202
           +P V  +NG  IP  G G+   WK  PGE     +  AV  AI+ G+ HID A  YG EK
Sbjct: 3   VPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEK 62

Query: 203 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382
           ++GEA    IKE  V R+D+F+TSK        D +  ++   L  L   Y DL+LIH P
Sbjct: 63  QIGEA----IKESGVPRKDIFLTSKTLFGLLADDPIE-SISNQLKTLQTDYFDLFLIHVP 117

Query: 383 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562
                     P D        + D    W  +E L ++GL K+IGVSN +  +LE +++ 
Sbjct: 118 ----------PNDD------INYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKV 161

Query: 563 ATVKPVVNQVECHPYLNQ 616
           A +KP VNQ+E HP L +
Sbjct: 162 AKIKPHVNQIEFHPLLQE 179


>UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 253

 Score =  116 bits (278), Expect = 6e-25
 Identities = 73/199 (36%), Positives = 98/199 (49%), Gaps = 7/199 (3%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P +  N+G  +P  G G WK         V +AI  GYR  D A                
Sbjct: 4   PTLKLNSGHEMPQVGFGLWKVDNATCADTVYNAIKTGYRLFDGAC--------------- 48

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDG 403
                    DLFI SKLWN+FH  D V    ++ L +  + Y DL+++H+P A  Y +  
Sbjct: 49  ---------DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVALRYVDPA 99

Query: 404 SLFP-----TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568
             +P     +D+ G +Q S     +TW+AME LV EGL KSIGVSNF    L  LL++A 
Sbjct: 100 VRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGVSNFQGALLIDLLRYAR 159

Query: 569 VKPVVNQVECHPYLNQKRL 625
           ++P   Q+E HPYL Q  L
Sbjct: 160 IRPATLQIEHHPYLVQNTL 178


>UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo
           sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo
           sapiens (Human)
          Length = 188

 Score = 70.9 bits (166), Expect(2) = 8e-25
 Identities = 34/68 (50%), Positives = 47/68 (69%)
 Frame = +2

Query: 146 AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQ 325
           AI+ G+ HID A+VY NE++VG      I +G V RED+F TSKLW+  HRP+LVR AL+
Sbjct: 2   AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55

Query: 326 ETLDNLNV 349
              D +++
Sbjct: 56  ILFDTVDL 63



 Score = 65.7 bits (153), Expect(2) = 8e-25
 Identities = 36/70 (51%), Positives = 44/70 (62%), Gaps = 2/70 (2%)
 Frame = +2

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHP 604
           +I F  VD   TW+AME        KSIGVSNFN + LE +L    +K  PV NQVECHP
Sbjct: 55  EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHP 106

Query: 605 YLNQKRLKEF 634
           Y NQ++L +F
Sbjct: 107 YFNQRKLLDF 116


>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 297

 Score =  115 bits (277), Expect = 8e-25
 Identities = 65/191 (34%), Positives = 104/191 (54%), Gaps = 1/191 (0%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N+G  IP  G GT+K     V  A+  A+  GYR  D A  Y NEKE+GEA+   + +  
Sbjct: 16  NSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKHG 75

Query: 245 VTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421
           ++R D+F+TSK +  + +  +  RG ++E+L +L   Y+D+YL+H+P+    D      D
Sbjct: 76  LSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSD-----ND 130

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601
                ++  + Y    + +E     G V+SIGVSN+    LE L  +A V P  NQ+E H
Sbjct: 131 DVNNAEYRKIAY----EVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYH 186

Query: 602 PYLNQKRLKEF 634
           P+  +  L+++
Sbjct: 187 PHFARIPLQKY 197


>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 285

 Score =  115 bits (276), Expect = 1e-24
 Identities = 69/180 (38%), Positives = 98/180 (54%), Gaps = 1/180 (0%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           NG  +P+ GLG +K++       +  AID  GYR ID A VY NE+ VG AI    K+  
Sbjct: 8   NGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAI----KQTK 63

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + RED+FIT+K+W + +  +    ++ ++L  L   Y+DL L+H P              
Sbjct: 64  IKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG------------ 111

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
                    DY   WKA+E L K+G+VK+IGVSNF + +L     H  VKPV+NQ+E HP
Sbjct: 112 ---------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHP 162


>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Leuconostoc mesenteroides subsp.
           mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
           diketogulonate reductase family - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 288

 Score =  115 bits (276), Expect = 1e-24
 Identities = 70/191 (36%), Positives = 98/191 (51%), Gaps = 4/191 (2%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T NNG  +P  G G ++    E  QAV DAI+ GYR ID A VYGNE E G+ +   I  
Sbjct: 5   TLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIAN 64

Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
            VV RE+LF+T+KLW +    +  +GA+ ++L  L   Y DL L+H P            
Sbjct: 65  AVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG---------- 114

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF-NSKQLERLLQHATVK---PVVN 586
                      D    +KA+     +G VKSIG+SNF  +K +E +    T+    P ++
Sbjct: 115 -----------DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQID 163

Query: 587 QVECHPYLNQK 619
           Q+E HPY  +K
Sbjct: 164 QIEFHPYYQEK 174


>UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus
           scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus
           scrofa (Pig)
          Length = 206

 Score =  105 bits (252), Expect(2) = 1e-24
 Identities = 63/127 (49%), Positives = 72/127 (56%), Gaps = 1/127 (0%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256
           IPV GLGTW++ PG EVT+AVK AID GYRH D AY+Y NE EVG  I +KI EGVV RE
Sbjct: 2   IPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRRE 61

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436
           DLFI SK                         YLDL  IHWP  +K      P D+SG I
Sbjct: 62  DLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGMI 99

Query: 437 QFSDVDY 457
             S+ D+
Sbjct: 100 VASNTDF 106



 Score = 30.3 bits (65), Expect(2) = 1e-24
 Identities = 11/15 (73%), Positives = 12/15 (80%)
 Frame = +2

Query: 575 PVVNQVECHPYLNQK 619
           PV NQ+E HPYL QK
Sbjct: 109 PVTNQIESHPYLTQK 123


>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
           Klebsiella pneumoniae|Rep: Putative uncharacterized
           protein - Klebsiella pneumoniae
          Length = 279

 Score =  114 bits (275), Expect = 1e-24
 Identities = 69/193 (35%), Positives = 99/193 (51%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +  N+G  +P  G G W     +V   ++ A+  G+RH D A  Y NE  VG A    ++
Sbjct: 6   ILLNDGYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRA----LR 61

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
              V RE LFITSK+            +  ETL+ L V+YL+L+LIHWP   K       
Sbjct: 62  YTEVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKN------ 115

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                        YV+TW+A   L   GL++SIGVSNF  + +ERL++   V P VNQ+E
Sbjct: 116 ------------LYVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLE 163

Query: 596 CHPYLNQKRLKEF 634
            HP+  Q  ++++
Sbjct: 164 LHPHFQQCDVRDY 176


>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
           Actinobacillus succinogenes 130Z|Rep: Aldo/keto
           reductase precursor - Actinobacillus succinogenes 130Z
          Length = 315

 Score =  114 bits (275), Expect = 1e-24
 Identities = 68/211 (32%), Positives = 109/211 (51%)
 Frame = +2

Query: 2   SSQAAAKIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCA 181
           ++ +A +I      K   V  NNG  +P+ G+G W   P +  ++V +A+  GYR ID A
Sbjct: 27  AADSAGQIFHPFDFKKRTVKLNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLIDTA 86

Query: 182 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLD 361
            +Y NE+ VG A    +++  + RE++FIT+K++ +    +    A+ E L  L+  Y+D
Sbjct: 87  RMYRNEQAVGRA----VRDSGIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYID 141

Query: 362 LYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQ 541
           L L+H+P                     D +    WK ME  VK G +++IG+SN++ K 
Sbjct: 142 LLLLHYP---------------------DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKT 180

Query: 542 LERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
             R++Q AT+ P V Q E H Y   K+ K F
Sbjct: 181 FNRIMQAATITPAVVQNEVHIYNQDKQTKAF 211


>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
           Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 287

 Score =  114 bits (275), Expect = 1e-24
 Identities = 72/191 (37%), Positives = 98/191 (51%)
 Frame = +2

Query: 38  APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217
           A  IP +   +G TIP  GLGTW     E   AV+ A+  GYR +D A+ Y NE+ VG  
Sbjct: 10  ASDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRG 69

Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397
               I+   V R +LFI+SK     H  D V+ A  E+L  L + +LD+++ HW      
Sbjct: 70  ----IRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW------ 119

Query: 398 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577
                P    GK       YVD WK +  L++EG VK+IGVSNF    L+ ++    V P
Sbjct: 120 -----PVPALGK-------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVP 167

Query: 578 VVNQVECHPYL 610
            VNQ++  P L
Sbjct: 168 DVNQIQLSPDL 178


>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 272

 Score =  114 bits (274), Expect = 2e-24
 Identities = 65/187 (34%), Positives = 100/187 (53%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247
           NG  IP  GLGTW+       + V+ A+ +GYRHID A VY NE+EVG+     ++   V
Sbjct: 7   NGARIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDG----VRASGV 62

Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 427
            R+D+F+T+K+W     P+ +  +++E+L  L +  +DL L+HWP               
Sbjct: 63  RRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPN-------------- 108

Query: 428 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607
                S V   +T  A+    + GL + IGVSNF    +E+ +  +    V NQVE HPY
Sbjct: 109 -----SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPY 163

Query: 608 LNQKRLK 628
           L+Q +++
Sbjct: 164 LDQAKVR 170


>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 293

 Score =  113 bits (272), Expect = 3e-24
 Identities = 72/194 (37%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKI 232
           +T  +G  +P FG+G W  +  E  QA+ +A D  GYRH+D A  Y NE + GEA    +
Sbjct: 19  ITMVDGYAMPRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEADCGEA----V 74

Query: 233 KEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           +E  V R +LF T+K++ N        R A++++L    + YLDL L+H P     DG  
Sbjct: 75  RECSVPRSELFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP-----DG-- 127

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL-QHATVKPVVN 586
                 GK +F     +D+W  +  LV+EG V+S+GVSNF    ++ L+     V PV N
Sbjct: 128 ------GK-KFR----LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCN 176

Query: 587 QVECHPYLNQKRLK 628
           Q+ECHP+  QK ++
Sbjct: 177 QIECHPFFAQKEVR 190


>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
           Griffithsia japonica|Rep: Mannose 6-phosphate reductase
           - Griffithsia japonica (Red alga)
          Length = 174

 Score =  113 bits (271), Expect = 4e-24
 Identities = 54/105 (51%), Positives = 68/105 (64%)
 Frame = +2

Query: 59  TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           T  +G  +P+ G GTWK+   E  QAV  A+  GYRHIDCA VY NE  VG AI+  I  
Sbjct: 7   TLQSGAKMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAISG 66

Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLI 373
           GVV REDLFITSK+WNT H  D V  + +++L +  V Y DL+L+
Sbjct: 67  GVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 19/44 (43%), Positives = 28/44 (63%)
 Frame = +2

Query: 500 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 631
           LV+ IGVSN++   L   L +A +KP VNQ E H Y  + +L++
Sbjct: 110 LVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRD 153


>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 270

 Score =  112 bits (270), Expect = 6e-24
 Identities = 65/192 (33%), Positives = 105/192 (54%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           +T NNG  +P+ GLGT+        +A+ +AI++GYR  D A +Y NE E+G AI + +K
Sbjct: 4   LTLNNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVK 63

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
            G + RE+ FI +KL  +    DL + +++++L  L + Y+D  LIH P  Y +  +++ 
Sbjct: 64  GG-IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMY- 118

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
                             +AME   K+G+++ IG+SNF +K     ++   V P +NQ E
Sbjct: 119 ------------------RAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCE 160

Query: 596 CHPYLNQKRLKE 631
            H  L QK L+E
Sbjct: 161 THLLLQQKPLRE 172


>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=5; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus brevis (strain ATCC 367 / JCM 1170)
          Length = 282

 Score =  112 bits (270), Expect = 6e-24
 Identities = 74/190 (38%), Positives = 100/190 (52%), Gaps = 1/190 (0%)
 Frame = +2

Query: 68  NGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           +G  +PV G GT+  +    +  A++ A D GYR  D A +Y NE  +G AI    ++  
Sbjct: 14  DGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAI----QQLG 69

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           + RE LF+TSK+       D    A++ +L  L   YLDL LIHWP   +E         
Sbjct: 70  LPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWP--VREH-------- 119

Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604
                     + DTW+A+E L  +G VKSIGVSN+    LE L   A   PVVNQVE HP
Sbjct: 120 ----------FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHP 169

Query: 605 YLNQKRLKEF 634
           YLNQ+ L ++
Sbjct: 170 YLNQQALADY 179


>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 283

 Score =  112 bits (270), Expect = 6e-24
 Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 1/204 (0%)
 Frame = +2

Query: 26  ISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205
           +S+   +   VT  NG  IP  G G +  K  E    V  A+D GYRHID A VYGNE  
Sbjct: 1   MSESQTESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDI 60

Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
            G+AI    ++  V R D+F+TSKL N        R A++ +L +L   Y+DL+LI  P 
Sbjct: 61  CGKAIVDWCEKNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLGT-YIDLFLIQSPA 118

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQH 562
             K+                    + +WKAME  V  G ++S+GVSN+  K L+ L   +
Sbjct: 119 GGKK------------------SRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASN 160

Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634
               P VNQ+E HP+L+Q  + ++
Sbjct: 161 PKFYPCVNQIELHPFLSQDDIVKY 184


>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
           n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
           reductase family - Lactobacillus acidophilus
          Length = 289

 Score =  112 bits (269), Expect = 8e-24
 Identities = 73/192 (38%), Positives = 98/192 (51%), Gaps = 1/192 (0%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           IP +  N+G  IP  G G ++ S   E  +AV+ AI  GYR ID A  Y N+  VGEAI 
Sbjct: 4   IPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGEAI- 62

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
              K   V R+D+F+T+KLW +    +    A+ E L  L   Y+D+ L+H  QAY    
Sbjct: 63  ---KNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAYG--- 114

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
                           D    W+A+E   K G  KSIGVSNF   QL  L   + VKPVV
Sbjct: 115 ----------------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVV 158

Query: 584 NQVECHPYLNQK 619
           NQ+E +P+  ++
Sbjct: 159 NQIEVNPWFQRE 170


>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
           Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 667

 Score =  111 bits (268), Expect = 1e-23
 Identities = 64/203 (31%), Positives = 100/203 (49%), Gaps = 18/203 (8%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250
           +P  G G  + + G   +   ++  A+D GYR +D A +YGNE  +G  + +    G   
Sbjct: 378 LPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GAPD 434

Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL------- 409
           R  +FI  K+W T HR   +  A + +LD L +   D Y +HWP+A    GSL       
Sbjct: 435 RRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKS 494

Query: 410 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
                   FP +  G I+   V     W+ +E L + G  +++G+ N +  QLE +++  
Sbjct: 495 VARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETG 554

Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634
           TV+P + QVE HPY  Q  L E+
Sbjct: 555 TVRPALVQVERHPYQPQTDLIEY 577


>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
           Bifidobacterium|Rep: Dehydrogenase or reductase protein
           - Bifidobacterium longum
          Length = 289

 Score =  111 bits (266), Expect = 2e-23
 Identities = 65/196 (33%), Positives = 95/196 (48%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           +P +   +G +IP  GLG  +     V   V+ A++ GYRHID A  Y NE  VG A+ +
Sbjct: 11  VPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAA 70

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
                   RE L++T+KL ++    D    A   +L  L + Y+D+Y+IHWP  +     
Sbjct: 71  SGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF----- 125

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
                        D    DTWKA   L  EG+ +++GV NF    L+RL +     P VN
Sbjct: 126 -------------DWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVN 172

Query: 587 QVECHPYLNQKRLKEF 634
           Q+E HP   Q+ +  F
Sbjct: 173 QIELHPTWQQREVVAF 188


>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
           bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
           bacterium HTCC2654
          Length = 278

 Score =  111 bits (266), Expect = 2e-23
 Identities = 69/186 (37%), Positives = 97/186 (52%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P VT  NG  +P  GLGTW     E  +AV  AI+ GYR ID A  Y NE  VG+     
Sbjct: 8   PTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQG---- 63

Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409
           I++  V R+++F+T+K+   +H  D  R A + +L+ L + Y+DL+LIHWP         
Sbjct: 64  IRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN-------- 115

Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
              DQ          YV+ ++ +  L+  GLV++IG SNF    L  L     V P VNQ
Sbjct: 116 --PDQG--------TYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQ 164

Query: 590 VECHPY 607
           ++  PY
Sbjct: 165 IQLDPY 170


>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
           Oxidoreductase - Xanthomonas campestris pv. campestris
           (strain 8004)
          Length = 267

 Score =  110 bits (265), Expect = 2e-23
 Identities = 67/187 (35%), Positives = 100/187 (53%), Gaps = 1/187 (0%)
 Frame = +2

Query: 77  TIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256
           T+P FGLGT++ K   V  +V++A+ +GYR ID A +Y NE +VG+AI     +  V R+
Sbjct: 2   TVPAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRD 57

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436
            LF+T+K+W      D ++ +LQE+L  L   Y+DL LIHWP          P DQ    
Sbjct: 58  QLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWPS---------PKDQ---- 104

Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV-VNQVECHPYLN 613
               V   +  +A+     +GL ++IGVSNF      + ++      +  NQ+E HPYL 
Sbjct: 105 ----VPMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQ 160

Query: 614 QKRLKEF 634
            + L  F
Sbjct: 161 NRTLIAF 167


>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
           Pezizomycotina|Rep: Aldo-keto reductase, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 283

 Score =  110 bits (265), Expect = 2e-23
 Identities = 67/193 (34%), Positives = 108/193 (55%), Gaps = 3/193 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N+   IP  G G ++S  G+  Q+   A++ GYRHID A  YGNEKEVGEA    +++  
Sbjct: 15  NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEA----LRKCG 70

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQ--YLDLYLIHWPQAYKEDGSLFPT 418
           + R D+F+T+K+ +    P+     L E+++ +  +  Y+DL+LIH             +
Sbjct: 71  IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------------S 117

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVE 595
             SG     ++     W+A+E L++EG  +SIGVSNF  K +E +  +A V  P VNQ+E
Sbjct: 118 SSSGSAGRKEL-----WQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIE 172

Query: 596 CHPYLNQKRLKEF 634
            HP+  Q+ ++ +
Sbjct: 173 LHPWCQQRVIEAY 185


>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 292

 Score =  110 bits (264), Expect = 3e-23
 Identities = 71/200 (35%), Positives = 106/200 (53%), Gaps = 9/200 (4%)
 Frame = +2

Query: 44  KIPVVTFNNGETIPVFGLGT----WKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGN 196
           K P ++  +G  +P+ G GT    +K  P + T     + +K A++ G+ HID A  YG 
Sbjct: 2   KWPALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGT 61

Query: 197 EKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIH 376
           E+EVG A    I+E  + RE LFIT+K+   +     V GAL  +L+ L + Y+DLYL+H
Sbjct: 62  EREVGIA----IRESGIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLH 114

Query: 377 WPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 556
            P        + P         +D+     WK +E +   G  +SIGVSNF    LE +L
Sbjct: 115 NPY-------VIP-------NLTDIQ--SAWKGLEAVKATGKARSIGVSNFQRNHLEAIL 158

Query: 557 QHATVKPVVNQVECHPYLNQ 616
           +  +V P +NQ+E HPYL +
Sbjct: 159 ETCSVVPAINQLEYHPYLQR 178


>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
           Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
           Caenorhabditis elegans
          Length = 321

 Score =  110 bits (264), Expect = 3e-23
 Identities = 74/197 (37%), Positives = 106/197 (53%), Gaps = 1/197 (0%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAIT 223
           IP    +N   +P+ GLGT  S  G    AV  +I   GYR ID A  YG EK++G A+ 
Sbjct: 2   IPTTVLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAV- 59

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
              K   V RE++F+++KLW      D V  A Q + + L   YLD+Y+IH PQ    D 
Sbjct: 60  ---KNCSVPREEMFLSTKLWPV-DCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQL--PDW 113

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
            +   +   K          TW+ ME L ++  V+SIGVSN++ + L+ LL+ A++ P  
Sbjct: 114 IVNQKETKEK----------TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163

Query: 584 NQVECHPYLNQKRLKEF 634
           NQVE HP+ +Q  LK +
Sbjct: 164 NQVELHPWFHQADLKNY 180


>UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 186

 Score =  109 bits (262), Expect = 5e-23
 Identities = 72/174 (41%), Positives = 93/174 (53%), Gaps = 1/174 (0%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N G  IP  GLGTWKS+PGEV +A+  A+  GYRHID A        +G           
Sbjct: 10  NPGALIPAVGLGTWKSEPGEVARALAHALKTGYRHIDAA--------LG----------- 50

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424
           V RE++FITSKLWNT H+P++  G LQ+TLD L V  LDLY         E   L P + 
Sbjct: 51  VPREEIFITSKLWNT-HQPNIKEG-LQKTLDALGVDCLDLY--------NETSDLLPVNP 100

Query: 425 SG-KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
            G +      D  +TW+ ME   K G  K+IGV+N++   LE LL     + +V
Sbjct: 101 DGTRAVDRSWDQSETWRQMEDFYKSGKAKAIGVANWSIPYLEELLADEVTRAIV 154


>UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 212

 Score =  109 bits (261), Expect = 7e-23
 Identities = 69/179 (38%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
 Frame = +2

Query: 65  NNGETIPVFGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           + G+ IP+ G+ T  +   P E +  ++  AI++GYRH DC   Y +EK +GEAI   +K
Sbjct: 5   STGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVK 64

Query: 236 EGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
            G++ +R++LFIT +             AL     NL + YLDLYLIHW  + K      
Sbjct: 65  LGLIKSRDELFITLQ-------------AL-----NLQLDYLDLYLIHWSVSLKPGNYEL 106

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589
           P ++   +    +D    WKAME   K  L K+IGVSNF+  +LE LLQ A++ P VNQ
Sbjct: 107 PVNKDDHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQ 162


>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
           Lin2739 protein - Listeria innocua
          Length = 283

 Score =  108 bits (260), Expect = 9e-23
 Identities = 70/190 (36%), Positives = 98/190 (51%), Gaps = 1/190 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           V  NNG  +P+ G GT++ +  GE  QAVK+AI  GYRHID A  Y NE+ VG  I +  
Sbjct: 4   VKLNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA-- 61

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
               V R++LFIT+K+W        V  +   +L  L + Y+DL LIH P          
Sbjct: 62  --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP---------- 109

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                    ++DV     W AME L  +G +K+IGVSNF   ++  L     + P VNQ+
Sbjct: 110 ---------YNDV--YGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQI 158

Query: 593 ECHPYLNQKR 622
           E +P+  Q +
Sbjct: 159 EINPFQQQSK 168


>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 273

 Score =  108 bits (260), Expect = 9e-23
 Identities = 67/184 (36%), Positives = 98/184 (53%), Gaps = 1/184 (0%)
 Frame = +2

Query: 77  TIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256
           TIP  G GT++ K  +   AV++A+D+GYRHID A  Y NE EVG+AI++      ++R 
Sbjct: 10  TIPTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRG 65

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436
           +LF+T+K+W      D    ++Q +L  LN  Y+DL L+HWP              S   
Sbjct: 66  ELFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP--------------SPDN 111

Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV-NQVECHPYLN 613
           + S  +Y+   KA +   + GL + IGVSNF   QL+  L       ++ NQ+E HP   
Sbjct: 112 KVSMAEYLKELKACK---ERGLTRHIGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQ 168

Query: 614 QKRL 625
            K L
Sbjct: 169 NKEL 172


>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
           Filobasidiella neoformans|Rep: Aldo-keto reductase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 303

 Score =  108 bits (259), Expect = 1e-22
 Identities = 71/209 (33%), Positives = 104/209 (49%), Gaps = 6/209 (2%)
 Frame = +2

Query: 23  IISKMAPKIPV------VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAY 184
           I+S+M+   PV      +  ++G  IP FGLG ++    E    VK A++ GYRH+D A 
Sbjct: 16  ILSEMSGPAPVKSLDARLKMHDGNAIPQFGLGVYEMNDKETYDCVKWALEAGYRHVDTAE 75

Query: 185 VYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 364
            Y NE   G+AI   +K    +RE++F+TSKL N           L+ +L    V+Y DL
Sbjct: 76  WYENEAPCGKAIADFLKATGTSREEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDL 134

Query: 365 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544
           YL+H             +   G +   +V     WKA+     +GLVKSIGVSNF  K +
Sbjct: 135 YLMH-------------SAIGGPVIRKNV-----WKALCDAQSQGLVKSIGVSNFGKKHI 176

Query: 545 ERLLQHATVKPVVNQVECHPYLNQKRLKE 631
           +  +      P VNQV+ HP++    + E
Sbjct: 177 QEFIDQKVPLPTVNQVDLHPFMRHPEIVE 205


>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
           Ostreococcus|Rep: Aldo/keto reductase family proteins -
           Ostreococcus tauri
          Length = 336

 Score =  107 bits (257), Expect = 2e-22
 Identities = 66/188 (35%), Positives = 100/188 (53%)
 Frame = +2

Query: 71  GETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250
           G T+P+   GT++ +      AV+DA+  G++H+D A VYGNE++VGEA+ +  +E    
Sbjct: 59  GITMPMLAFGTYRLRGETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACHRE---V 115

Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430
            E +F+TSK+  +  R +    A    ++    +  DL L+HWP   KE     P  +  
Sbjct: 116 SERIFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTPDLVLVHWPGRDKES----PDSE-- 169

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610
             +  D     TW+A+E  +K G  ++IGVSN+    L  LLQ   VKP VNQ+E H   
Sbjct: 170 --RHRDARRW-TWRALENALKMGQCRAIGVSNYELSHLRELLQFCDVKPAVNQIELHARF 226

Query: 611 NQKRLKEF 634
            Q  L+ F
Sbjct: 227 PQTELRAF 234


>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 287

 Score =  106 bits (255), Expect = 4e-22
 Identities = 67/193 (34%), Positives = 105/193 (54%), Gaps = 4/193 (2%)
 Frame = +2

Query: 68  NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI-KEGV 244
           NG  IP  G+G +     +    V+ A+D+GYR ID A  Y NE+E GE I + + K+  
Sbjct: 14  NGSRIPACGVGVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKDKN 73

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNL-NVQYLDLYLIHWPQAYKEDGSLFPTD 421
             RED+  T+K+ N     D    +L+E+L+ + +++Y+DL LIH P + K+        
Sbjct: 74  NKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLSDKK-------- 125

Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVE 595
                       ++TWKA++  V  G+VKSIGVSNF    ++ L   +    KP+VNQ+E
Sbjct: 126 ----------TRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175

Query: 596 CHPYLNQKRLKEF 634
             P+L +K L ++
Sbjct: 176 LSPWLMRKDLVDY 188


>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
           n=1; Rhodococcus sp. RHA1|Rep: Probable
           2,5-didehydrogluconate reductase - Rhodococcus sp.
           (strain RHA1)
          Length = 265

 Score =  106 bits (254), Expect = 5e-22
 Identities = 68/177 (38%), Positives = 91/177 (51%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           IP  GLGTW     + T+AV   I+ GYR ID A +Y NE  VG A+     E  V RE+
Sbjct: 4   IPPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREE 59

Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439
           LF+T+KL  + H    +RGA++ +L NL +  LDL+LIHWP          P        
Sbjct: 60  LFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWP---------LPRHNR---- 106

Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610
                YV  ++AM      GLV+ +GVSNF    L R++      P VNQ++  P L
Sbjct: 107 -----YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSL 158


>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
           Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 665

 Score =  105 bits (253), Expect = 7e-22
 Identities = 61/202 (30%), Positives = 96/202 (47%), Gaps = 18/202 (8%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKD---AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250
           +P  G G  + + GE    V     A+D GYR +D A +YGNE  +GE + +    G   
Sbjct: 376 LPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GAPD 432

Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL------- 409
           RE +F+  K W T HR + +  A   + + L +   D Y +HWP A +  G L       
Sbjct: 433 RERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAEKP 492

Query: 410 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
                   FP  + G+   +DV     W+ +E + + G  +++G+ N +  QLE +L+  
Sbjct: 493 VERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGICNVSRAQLETVLETG 552

Query: 566 TVKPVVNQVECHPYLNQKRLKE 631
            + P + QVE HPY  +  L E
Sbjct: 553 EIDPALVQVERHPYRPRNGLVE 574


>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
           Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 279

 Score =  105 bits (251), Expect = 1e-21
 Identities = 62/185 (33%), Positives = 92/185 (49%), Gaps = 1/185 (0%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256
           +P+ GLGTW+++  E   ++V+ A++ GYRHID A  Y NE  VG+ I +      V R+
Sbjct: 17  MPMLGLGTWQNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA----ADVDRD 72

Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436
           D+F+ +K+W +    D V    +E+LD L V  +DL  +HW     E     P       
Sbjct: 73  DIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP------- 125

Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616
                       A + LV  GL+ ++GVSNF    +E  +         NQVE HP+L Q
Sbjct: 126 ------------AFDELVDRGLIDNVGVSNFEPHHVETAMDVLDAPVFANQVETHPFLQQ 173

Query: 617 KRLKE 631
             L+E
Sbjct: 174 SELRE 178


>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
           Lmo2592 protein - Listeria monocytogenes
          Length = 283

 Score =  104 bits (250), Expect = 2e-21
 Identities = 70/188 (37%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232
           V  NNG  +P+ G GT++ +   E   AVKDAI  GYRHID A  Y NE+ VG  I +  
Sbjct: 4   VKLNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA-- 61

Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412
               V R++LFIT+K+W        V  +   +L  L + Y+DL LIH P          
Sbjct: 62  --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP---------- 109

Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592
                    F+DV     W AME L   G +++IGVSNF+  ++  L     V P VNQ+
Sbjct: 110 ---------FNDV--YGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQI 158

Query: 593 ECHPYLNQ 616
           E +P+  Q
Sbjct: 159 EVNPFQQQ 166


>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
           reductase; n=5; Pezizomycotina|Rep: Related to 2,
           5-diketo-D-gluconic acid reductase - Neurospora crassa
          Length = 289

 Score =  104 bits (249), Expect = 2e-21
 Identities = 66/196 (33%), Positives = 102/196 (52%), Gaps = 5/196 (2%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           V  +NG +IP   LG +     E T+AV+ A+  GYR  D A  Y NE+E G+AI S + 
Sbjct: 13  VKLSNGLSIPQIQLGLYMMSGPETTRAVRWALGAGYRGFDSAQWYYNEREAGQAILSFLS 72

Query: 236 E----GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
                  +TR+D+  TSKL +     D VR ++ +++    + Y+DL+L+H P   +E  
Sbjct: 73  SPENTAGLTRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSPLGGRE-- 130

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPV 580
                             + +WKA+E  V  G VK  GVSN+  K L+ ++     +KP+
Sbjct: 131 ----------------ARLTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPL 174

Query: 581 VNQVECHPYLNQKRLK 628
           VNQ+ECHP+  Q  ++
Sbjct: 175 VNQIECHPFNTQPEIR 190


>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
           n=1; Haloarcula marismortui|Rep: Oxidoreductase
           aldo/keto reductase family - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 302

 Score =  104 bits (249), Expect = 2e-21
 Identities = 66/192 (34%), Positives = 97/192 (50%), Gaps = 2/192 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N   T+P  G GT+++   +   AVK+A+D GY HID A  Y NE  VG A    I++  
Sbjct: 15  NGTTTVPTLGFGTYRTGGYKCYNAVKNALDCGYTHIDTAMAYENEAAVGRA----IEQSS 70

Query: 245 VTREDLFITSKLWNTFHRPDLVR--GALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418
           V RED+F+T+K+       +  R   A +  L+ L  +YLDL L+HW             
Sbjct: 71  VDREDIFLTTKIKGYPEMVEYERLIEAAKGCLERLGTEYLDLLLVHWWNPL--------- 121

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598
                      D  +T+ A+  LV +GLV  IGVSNF+ K+L++ ++ +      NQ+E 
Sbjct: 122 ----------ADMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQIEY 171

Query: 599 HPYLNQKRLKEF 634
           HPY   + L  F
Sbjct: 172 HPYWGDEELVRF 183


>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
           baltica OS145|Rep: Aldo/keto reductase - Idiomarina
           baltica OS145
          Length = 263

 Score =  103 bits (248), Expect = 3e-21
 Identities = 64/185 (34%), Positives = 95/185 (51%), Gaps = 1/185 (0%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           IP FG+GT++ +  E+T  V  AID+GY HID A  YGNE +VG+A+         T +D
Sbjct: 2   IPQFGMGTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKD 55

Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439
           +F+T+K+W        V  +LQ + D L    +DL LIHWP          P D      
Sbjct: 56  VFVTTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWPS---------PND------ 100

Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV-NQVECHPYLNQ 616
             +V   +T  A++   ++GL+K +GVSNF    L R   H     ++ NQ+E HP+   
Sbjct: 101 --EVPVEETLDALQKAQQDGLIKHLGVSNFTIDLLNRAAAHVGKDEILTNQIEVHPFFQN 158

Query: 617 KRLKE 631
             + +
Sbjct: 159 HAITD 163


>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 289

 Score =  103 bits (248), Expect = 3e-21
 Identities = 71/190 (37%), Positives = 96/190 (50%)
 Frame = +2

Query: 47  IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226
           IP++   +G  IP+  LG      G V    K  I+ G+ H+DCA +YG E+EV  A   
Sbjct: 3   IPLLRLRDGNQIPL-DLGDTTFGQGLV-DLTKAVIEKGFYHLDCAEMYGTEEEVAIA--- 57

Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406
            IKE  V RE LFIT+K+       D +  A+ ++L  +   Y DLYLIH P   K    
Sbjct: 58  -IKESGVPREKLFITNKVAQGI---DDIEAAIDQSLQKMQTNYFDLYLIHIPFFAK---- 109

Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586
                       S+ D+   WK ME + K G  +SIGVSN+    +E  L+ AT  PV N
Sbjct: 110 ------------SEEDFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPPVTN 157

Query: 587 QVECHPYLNQ 616
           Q+E H YL +
Sbjct: 158 QIEYHAYLQR 167


>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 275

 Score =  103 bits (248), Expect = 3e-21
 Identities = 62/194 (31%), Positives = 100/194 (51%), Gaps = 1/194 (0%)
 Frame = +2

Query: 56  VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235
           V  NNG   P F  G++     +   +V  A+  GYRHID A +Y NE + G AI   ++
Sbjct: 6   VKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFME 65

Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
           E    RED++ TSKL N          ++  ++    + Y+DL+L+H P           
Sbjct: 66  ETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG--------- 115

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL-QHATVKPVVNQV 592
                       D +++WKA+E  V+EG +++IGVSNF    ++ LL  H  + P VNQ+
Sbjct: 116 ------------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQI 163

Query: 593 ECHPYLNQKRLKEF 634
           E HP+ +Q+++ ++
Sbjct: 164 ELHPFCSQQKVVDY 177


>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
           Magnoliophyta|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 304

 Score =  103 bits (247), Expect = 4e-21
 Identities = 76/201 (37%), Positives = 96/201 (47%), Gaps = 1/201 (0%)
 Frame = +2

Query: 35  MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214
           M+  I     N G  +P  GLGTW+S PG V QAV  AI +GYRHIDCA VYGNE+E+G 
Sbjct: 1   MSDDIRFFQLNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGI 60

Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394
            +     +GVV REDL+ITSKLW T        G  ++  +              P A  
Sbjct: 61  VLKKLFDDGVVKREDLWITSKLWCTESCTRRCTGGTKQNFEG-------------PAA-- 105

Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQHATV 571
               L P     +  F    ++ TWK         + ++ G    +S  L RL L  A V
Sbjct: 106 ---RLHPLANEYEKGFC---WLQTWKTS----PNQIYQAHGEQWKHSMILARLELLVARV 155

Query: 572 KPVVNQVECHPYLNQKRLKEF 634
            P V QVECHP   Q +L  F
Sbjct: 156 PPAVIQVECHPSWQQSKLHAF 176


>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
           n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
           reductase family - Mycoplasma penetrans
          Length = 299

 Score =  103 bits (246), Expect = 5e-21
 Identities = 65/194 (33%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
 Frame = +2

Query: 50  PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229
           P++T N+G  IP+ GLGT          A+K A++IG R  D A +YGNEKEVGE     
Sbjct: 35  PLLTLNDGYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGET---- 90

Query: 230 IKEGVVTREDLFITSKLW--NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
           I+E  + R ++F+ +KL+    F  P+    A++E L+ LN  Y+D+ L+H P       
Sbjct: 91  IRESNINRNEIFVITKLYPGAQFANPE---KAIEEALNKLNTDYIDMMLLHHP------- 140

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
                   G+      + V  +KA+E  +++G +KS+G+SN+  K++   L    +KP +
Sbjct: 141 --------GE------NDVKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSL 186

Query: 584 NQVECHPYLNQKRL 625
            Q E H Y  +K +
Sbjct: 187 IQNEIHIYYQEKEV 200


>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 309

 Score =  103 bits (246), Expect = 5e-21
 Identities = 69/214 (32%), Positives = 107/214 (50%), Gaps = 4/214 (1%)
 Frame = +2

Query: 5   SQAAAKIISKMAPK---IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHID 175
           S+A   I   + P    IP  T  +G+T+P  GLGT+     ++  +V+ A+  GY HID
Sbjct: 17  SEAVVSISEPLNPPRVTIPTQTLPSGDTLPALGLGTYALDDDQIADSVRAALSSGYTHID 76

Query: 176 CAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK-LWNTFHRPDLVRGALQETLDNLNVQ 352
            A  Y NE+ +GE +          R+D+F+TSK L        L++ + + +L+ L   
Sbjct: 77  TAEGYHNEEAIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQ-SCEASLERLETD 129

Query: 353 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 532
           YLDLYLIHWP          P           +   ++ +AM  L   GLV+++GVSNF+
Sbjct: 130 YLDLYLIHWPN---------PA----------ISLRESLQAMAELHDRGLVRNVGVSNFS 170

Query: 533 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634
           + QL      + V   VNQ+E HP+  +  L ++
Sbjct: 171 AYQLSCANHISEVPIAVNQIEFHPWFQRPNLVDY 204


>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Shewanella sp. (strain ANA-3)
          Length = 280

 Score =  102 bits (245), Expect = 6e-21
 Identities = 66/186 (35%), Positives = 100/186 (53%), Gaps = 1/186 (0%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           +P+ G GT++ K      AV  A++ G RHID A +YGNE+ VG+AI +      + RE+
Sbjct: 17  MPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINT----SGIPREE 72

Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439
           LFIT+K+W      +    ++ ++L  L  +YLDL LIHWP    E              
Sbjct: 73  LFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEP------------- 119

Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV-VNQVECHPYLNQ 616
            S V+Y+   KA   ++ +GL + IGVSNF + QL + +       +  NQVE HPYL  
Sbjct: 120 -SMVEYLSELKA---VLDKGLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLIN 175

Query: 617 KRLKEF 634
           +++ +F
Sbjct: 176 RKVTDF 181


>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
           Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
           clavatus
          Length = 283

 Score =  102 bits (245), Expect = 6e-21
 Identities = 64/188 (34%), Positives = 101/188 (53%), Gaps = 3/188 (1%)
 Frame = +2

Query: 65  NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244
           N+   IP  G G ++S   +  Q+   A+  GYR+ID A  Y NE+EVGEA    ++   
Sbjct: 15  NSSVRIPRLGFGVYRSPTRQCVQSCLTALQAGYRNIDTAQFYANEQEVGEA----LRTSG 70

Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQ--YLDLYLIHWPQAYKEDGSLFPT 418
           + R D+F+T+K+ +    P+     L E+++ +  +  Y+DL+LIH             +
Sbjct: 71  IPRSDVFVTTKILSPAGSPEATYKKLLESVEKIGGENGYVDLFLIH-------------S 117

Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVE 595
             SG     ++     W+A+E L++EG  KSIGVSNF  K +E +  +A V  P VNQ+E
Sbjct: 118 SSSGSAGRKEL-----WQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIE 172

Query: 596 CHPYLNQK 619
            HP+  Q+
Sbjct: 173 LHPWCQQR 180


>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
           Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
           Bradyrhizobium sp. (strain ORS278)
          Length = 273

 Score =  101 bits (243), Expect = 1e-20
 Identities = 61/188 (32%), Positives = 94/188 (50%)
 Frame = +2

Query: 71  GETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250
           G  +P  GLGT++ +      AV+ A+ +GYRHID A +Y NE  +G A+ +      + 
Sbjct: 8   GVRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQIA 63

Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430
           REDL +T+K+W     PD +R A   +L  L + ++DLYLIHWP      G   P     
Sbjct: 64  REDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPAT----GMNLPA---- 115

Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610
                        + +  L +EG  ++IGV+NF    L++ ++        NQVE H  L
Sbjct: 116 -----------AMETLMALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVML 164

Query: 611 NQKRLKEF 634
           +Q +L  +
Sbjct: 165 DQSKLMAY 172


>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=1; Rhodobacterales bacterium HTCC2150|Rep:
           2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
           bacterium HTCC2150
          Length = 334

 Score =  101 bits (243), Expect = 1e-20
 Identities = 73/209 (34%), Positives = 94/209 (44%), Gaps = 7/209 (3%)
 Frame = +2

Query: 2   SSQAAAKIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCA 181
           S+QA       M       T N   TIP  G GT+     +    +  AI  GYRHID A
Sbjct: 22  SNQANNGTEHPMTNTATTFTLNTTTTIPAVGFGTYLISNDDAKSTISAAIQAGYRHIDTA 81

Query: 182 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW--NTF--HRPDLVRGALQE---TLDN 340
             Y NEK VG  I + ++   +TR+DLF+T+KLW  N      P      L E   +L  
Sbjct: 82  SGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLAR 141

Query: 341 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 520
           L + Y+DLYLIH P  Y  D  L                 + W+A+  L   G  +SIGV
Sbjct: 142 LGLDYVDLYLIHAP--YGGDMRL-----------------EQWRALLELQANGKARSIGV 182

Query: 521 SNFNSKQLERLLQHATVKPVVNQVECHPY 607
           SNFN   L  +       P  NQ+E HP+
Sbjct: 183 SNFNESHLNEIKAAGLPMPDANQIELHPW 211


>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
           marismortui|Rep: Oxidoreductase - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 264

 Score =  101 bits (241), Expect = 2e-20
 Identities = 63/181 (34%), Positives = 95/181 (52%)
 Frame = +2

Query: 92  GLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFIT 271
           G+GTW      V ++V+  +++GY H+D A  Y NE E+GEA+          RED+F+T
Sbjct: 3   GVGTWDIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVFLT 56

Query: 272 SKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDV 451
           SK+       + V  A + +LD L   YLDLYL+HWP            + +  I+    
Sbjct: 57  SKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP------------NPATSIR---- 100

Query: 452 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 631
              +T  AM  L  +G ++++GVSNF++ QL      A V   VNQ+E HP+  Q ++ E
Sbjct: 101 ---ETMNAMATLHDQGKIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVE 157

Query: 632 F 634
           F
Sbjct: 158 F 158


>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 301

 Score =  100 bits (239), Expect = 3e-20
 Identities = 62/193 (32%), Positives = 105/193 (54%), Gaps = 2/193 (1%)
 Frame = +2

Query: 62  FNNGETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238
           F++G  +P  GLG  + +  + +  +++ A+  GYR  D A +Y NE  +G ++   + +
Sbjct: 14  FSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLPQ 73

Query: 239 GVVTREDLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415
             +TRED+FIT+K+        +     L  +L  L   Y+DL LIH+P+  ++ G+   
Sbjct: 74  FGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRD-RDTGN--- 129

Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595
            D   +I  S    V  W+ +E   + G V+SIGVSN+    L  + ++A ++PV+NQ E
Sbjct: 130 -DDDYEINKSRRKIV--WQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYE 186

Query: 596 CHPYLNQKRLKEF 634
             PYL +  LK+F
Sbjct: 187 YQPYLTRPTLKKF 199


>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
           Parvularcula bermudensis HTCC2503|Rep: Putative
           uncharacterized protein - Parvularcula bermudensis
           HTCC2503
          Length = 278

 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 58/179 (32%), Positives = 90/179 (50%)
 Frame = +2

Query: 80  IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259
           IP  G GTW+ +  +   + + AI+ GYRHID A +Y NEK+VGE     IK+  + R++
Sbjct: 11  IPRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEG----IKDSGIPRDE 66

Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439
           LF+T+K+WN   +      A+ E+LD L + Y++L L+HWP                   
Sbjct: 67  LFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWP------------------- 107

Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616
            +D+   D    +  + + G  K IG+SN+N  Q    +  +       Q E HP L+Q
Sbjct: 108 INDMPIADQVGPLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQ 166


>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 313

 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 74/198 (37%), Positives = 100/198 (50%), Gaps = 13/198 (6%)
 Frame = +2

Query: 65  NNGETIP---VFGLGT-WKSKPG-------EVTQAVKDAIDI-GYRHIDCAYVYGNEKEV 208
           NNG  IP   + G GT W  +PG       E+ + +K A+ + G  HID A  YG   E+
Sbjct: 11  NNGNQIPSISIIGTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYPEL 70

Query: 209 GEAITSKIKEGVVTREDLFITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385
            +A+    KE    R ++FIT K    T    D + G L   L  L + Y+DLYLIH P 
Sbjct: 71  AKAL----KESSKPRSEIFITDKYSTQTKFTNDPIEG-LNTGLKTLGLDYVDLYLIHSP- 124

Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565
                   F  +  G +    V     WK ME L KEG  KSIGVSNF+ K +E +L+ A
Sbjct: 125 -------FFDPEFKGSLTLEKV-----WKDMETLYKEGKAKSIGVSNFSVKNIEEILKIA 172

Query: 566 TVKPVVNQVECHPYLNQK 619
            +KP VNQ+E + +L  +
Sbjct: 173 GIKPQVNQIEFNAFLQNQ 190


>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 274

 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 68/184 (36%), Positives = 93/184 (50%), Gaps = 9/184 (4%)
 Frame = +2

Query: 71  GETIPVFGLGTWK---------SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223
           GE IP  GLGTW          S+  E+ + +K AI +GY HID A  YG      E I 
Sbjct: 10  GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGG-HTEELIG 68

Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403
             IK+    REDLFI SK+W T  R D +  +L+ TL  L+  Y+DLYLIHWP       
Sbjct: 69  KAIKD--FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWPN------ 120

Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583
                         ++   +T  AM   V++GL++ IGVSNF+ + LE  +  +    V 
Sbjct: 121 -------------PEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVC 167

Query: 584 NQVE 595
           +QV+
Sbjct: 168 DQVK 171


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 679,601,185
Number of Sequences: 1657284
Number of extensions: 15037284
Number of successful extensions: 64348
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 58145
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 63465
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46881492319
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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