BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fmgV11a18f (634 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 286 3e-76 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 269 4e-71 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 264 1e-69 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 259 3e-68 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 252 7e-66 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 243 3e-63 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 242 6e-63 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 230 2e-59 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 229 4e-59 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 226 3e-58 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 226 3e-58 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 223 2e-57 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 121 4e-55 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 216 4e-55 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 215 7e-55 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 215 7e-55 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 214 2e-54 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 213 4e-54 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 212 7e-54 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 211 1e-53 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 211 1e-53 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 207 1e-52 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 207 1e-52 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 206 3e-52 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 205 6e-52 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 202 6e-51 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 198 7e-50 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 198 7e-50 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 197 2e-49 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 197 2e-49 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 197 2e-49 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 196 3e-49 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 196 5e-49 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 194 1e-48 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 194 2e-48 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 193 3e-48 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 191 1e-47 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 190 2e-47 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 190 2e-47 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 189 4e-47 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 184 1e-45 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 184 2e-45 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 182 5e-45 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 182 6e-45 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 180 3e-44 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 177 2e-43 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 176 3e-43 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 176 3e-43 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 176 4e-43 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 175 6e-43 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 175 7e-43 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 175 7e-43 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 174 1e-42 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 174 1e-42 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 173 2e-42 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 172 5e-42 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 171 9e-42 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 171 1e-41 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 170 3e-41 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 169 5e-41 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 169 6e-41 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 169 6e-41 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 169 6e-41 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 168 8e-41 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 168 8e-41 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 167 2e-40 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 167 2e-40 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 167 2e-40 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 167 3e-40 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 166 4e-40 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 165 6e-40 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 165 6e-40 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 165 1e-39 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 164 2e-39 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 162 5e-39 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 162 5e-39 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 162 5e-39 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 162 5e-39 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 161 1e-38 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 160 3e-38 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 160 3e-38 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 159 5e-38 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 159 7e-38 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 157 2e-37 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 157 2e-37 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 157 2e-37 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 157 3e-37 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 156 5e-37 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 155 1e-36 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 154 1e-36 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 154 1e-36 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 154 2e-36 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 153 3e-36 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 153 3e-36 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 153 3e-36 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 153 3e-36 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 153 3e-36 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 153 3e-36 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 153 3e-36 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 152 6e-36 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 152 8e-36 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 151 1e-35 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 151 1e-35 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 151 2e-35 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 150 3e-35 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 149 5e-35 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 149 5e-35 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 149 5e-35 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 149 7e-35 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 148 1e-34 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 147 2e-34 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 147 2e-34 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 147 2e-34 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 147 2e-34 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 146 3e-34 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 146 4e-34 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 146 4e-34 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 145 9e-34 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 145 9e-34 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 145 9e-34 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 144 2e-33 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 144 2e-33 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 142 5e-33 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 142 6e-33 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 142 8e-33 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 141 1e-32 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 140 2e-32 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 140 2e-32 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 140 3e-32 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 140 3e-32 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 139 4e-32 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 138 8e-32 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 138 1e-31 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 137 2e-31 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 137 2e-31 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 136 3e-31 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 136 3e-31 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 136 4e-31 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 136 4e-31 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 136 5e-31 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 134 2e-30 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 133 3e-30 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 132 5e-30 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 132 7e-30 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 132 9e-30 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 132 9e-30 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 131 1e-29 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 130 2e-29 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 130 2e-29 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 130 2e-29 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 130 2e-29 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 130 3e-29 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 130 4e-29 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 130 4e-29 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 129 5e-29 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 129 6e-29 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 129 6e-29 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 129 6e-29 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 128 8e-29 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 127 2e-28 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 127 2e-28 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 127 3e-28 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 127 3e-28 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 126 3e-28 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 126 3e-28 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 126 3e-28 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 126 4e-28 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 126 6e-28 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 126 6e-28 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 126 6e-28 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 126 6e-28 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 125 8e-28 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 124 2e-27 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 124 2e-27 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 124 2e-27 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 124 2e-27 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 124 2e-27 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 124 2e-27 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 123 4e-27 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 123 4e-27 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 123 4e-27 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 122 7e-27 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 122 7e-27 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 122 1e-26 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 121 1e-26 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 119 5e-26 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 119 5e-26 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 119 7e-26 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 118 9e-26 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 118 9e-26 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 118 2e-25 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 117 2e-25 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 117 3e-25 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 117 3e-25 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 116 4e-25 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 116 6e-25 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 116 6e-25 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 116 6e-25 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 116 6e-25 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 71 8e-25 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 115 8e-25 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 115 1e-24 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 115 1e-24 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 105 1e-24 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 114 1e-24 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 114 1e-24 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 114 1e-24 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 114 2e-24 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 113 3e-24 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 113 4e-24 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 112 6e-24 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 112 6e-24 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 112 6e-24 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 112 8e-24 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 111 1e-23 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 111 2e-23 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 111 2e-23 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 110 2e-23 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 110 2e-23 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 110 3e-23 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 110 3e-23 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 109 5e-23 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 109 7e-23 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 108 9e-23 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 108 9e-23 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 108 1e-22 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 107 2e-22 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 106 4e-22 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 106 5e-22 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 105 7e-22 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 105 1e-21 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 104 2e-21 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 104 2e-21 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 104 2e-21 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 103 3e-21 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 103 3e-21 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 103 3e-21 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 103 4e-21 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 103 5e-21 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 103 5e-21 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 102 6e-21 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 102 6e-21 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 101 1e-20 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 101 1e-20 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 101 2e-20 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 100 3e-20 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 99 8e-20 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 99 8e-20 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 99 8e-20 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 99 8e-20 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 99 1e-19 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 98 1e-19 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 97 2e-19 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 97 3e-19 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 97 4e-19 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 95 1e-18 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 95 1e-18 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 95 1e-18 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 95 2e-18 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 94 2e-18 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 93 5e-18 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 92 1e-17 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 90 4e-17 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 90 4e-17 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 90 5e-17 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 90 5e-17 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 88 1e-16 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 87 3e-16 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 87 3e-16 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 87 4e-16 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 86 6e-16 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 85 1e-15 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 85 2e-15 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 82 9e-15 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 82 1e-14 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 82 1e-14 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 81 2e-14 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 81 2e-14 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 81 3e-14 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 79 9e-14 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 79 9e-14 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 79 1e-13 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 79 1e-13 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 78 2e-13 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 77 3e-13 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 77 5e-13 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 76 6e-13 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 75 1e-12 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 75 2e-12 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 74 2e-12 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 74 3e-12 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 73 8e-12 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 73 8e-12 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 71 2e-11 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 71 2e-11 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 71 2e-11 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 69 7e-11 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 69 1e-10 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 2e-10 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 68 2e-10 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 68 2e-10 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 68 2e-10 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 67 3e-10 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-10 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 66 9e-10 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 65 1e-09 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 65 2e-09 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 64 2e-09 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 64 2e-09 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 64 2e-09 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 64 3e-09 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 64 4e-09 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 64 4e-09 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 62 8e-09 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 62 8e-09 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 62 8e-09 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 62 8e-09 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 62 8e-09 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 62 1e-08 UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 62 1e-08 UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 62 1e-08 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 61 2e-08 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 61 2e-08 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 61 2e-08 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 60 3e-08 UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 60 6e-08 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 59 8e-08 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 59 1e-07 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 58 2e-07 UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07 UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 56 5e-07 UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 56 5e-07 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 56 7e-07 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 56 7e-07 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 56 9e-07 UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 55 1e-06 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 54 2e-06 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 54 2e-06 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 53 7e-06 UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 52 9e-06 UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 52 2e-05 UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 52 2e-05 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 51 2e-05 UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 51 3e-05 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 51 3e-05 UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 51 3e-05 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 50 4e-05 UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 50 4e-05 UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 50 5e-05 UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 50 5e-05 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 50 6e-05 UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 50 6e-05 UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 49 8e-05 UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2... 49 1e-04 UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 49 1e-04 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 48 1e-04 UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 48 1e-04 UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 48 1e-04 UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 48 2e-04 UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 48 2e-04 UniRef50_Q966L2 Cluster: Putative uncharacterized protein; n=2; ... 48 2e-04 UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 48 2e-04 UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 48 2e-04 UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 2e-04 UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 47 3e-04 UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 47 3e-04 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 47 3e-04 UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 47 4e-04 UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 47 4e-04 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 47 4e-04 UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 46 6e-04 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 46 6e-04 UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 46 6e-04 UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 40 6e-04 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 46 8e-04 UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 8e-04 UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 46 8e-04 UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 46 8e-04 UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 46 0.001 UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 46 0.001 UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 45 0.001 UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 45 0.001 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 45 0.001 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 45 0.002 UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 44 0.002 UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 44 0.002 UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.002 UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 44 0.002 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 44 0.002 UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 44 0.002 UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 44 0.002 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 44 0.003 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 44 0.004 UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 44 0.004 UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004 UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 44 0.004 UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 43 0.005 UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 43 0.005 UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 43 0.005 UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 43 0.005 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 43 0.005 UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 43 0.005 UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 43 0.007 UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.007 UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri... 43 0.007 UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 43 0.007 UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 43 0.007 UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 42 0.009 UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 42 0.009 UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 42 0.009 UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig... 42 0.009 UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 42 0.009 UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 42 0.009 UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 42 0.009 UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires... 42 0.012 UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 42 0.012 UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 42 0.012 UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.012 UniRef50_A2TIR8 Cluster: Receptor for egg jelly protein 9; n=9; ... 42 0.012 UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 42 0.012 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 42 0.012 UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 42 0.016 UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 42 0.016 UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 42 0.016 UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 42 0.016 UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 42 0.016 UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 42 0.016 UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 42 0.016 UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016 UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 41 0.022 UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 41 0.022 UniRef50_Q41CR8 Cluster: Aldo/keto reductase; n=1; Exiguobacteri... 41 0.022 UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 41 0.022 UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 41 0.022 UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 41 0.022 UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 41 0.022 UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 41 0.028 UniRef50_Q3A7S5 Cluster: Predicted oxidoreductases of the aldo/k... 41 0.028 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 41 0.028 UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 41 0.028 UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 41 0.028 UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 41 0.028 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 41 0.028 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 40 0.038 UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 40 0.038 UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 40 0.038 UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla... 40 0.038 UniRef50_Q6WN58 Cluster: Glutamate-cysteine ligase modifier subu... 40 0.038 UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.038 UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 40 0.038 UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 40 0.050 UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 40 0.050 UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga... 40 0.050 UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 40 0.050 UniRef50_Q4QEB9 Cluster: Protein kinase, putative; n=3; Leishman... 40 0.050 UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.050 UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 40 0.050 UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2; Des... 40 0.050 UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 40 0.050 UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.066 UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 40 0.066 UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 40 0.066 UniRef50_A7RWF3 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.066 UniRef50_P48507 Cluster: Glutamate--cysteine ligase regulatory s... 40 0.066 UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 39 0.087 UniRef50_Q5FJ72 Cluster: Predicted oxidoreductase; n=1; Lactobac... 39 0.087 UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 39 0.087 UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 39 0.087 UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 39 0.087 UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 39 0.087 UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 39 0.087 UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 39 0.087 UniRef50_UPI0000605361 Cluster: PREDICTED: hypothetical protein;... 39 0.11 UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 39 0.11 UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 39 0.11 UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St... 39 0.11 UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.11 UniRef50_Q17N98 Cluster: Gamma-glutamylcysteine synthetase, puta... 39 0.11 UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ... 39 0.11 UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 38 0.15 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 38 0.15 UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 38 0.15 UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.15 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 286 bits (701), Expect = 3e-76 Identities = 128/197 (64%), Positives = 150/197 (76%), Gaps = 1/197 (0%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 +P F NG +IP+FGLGTW S PG+V QAVKDAID+GYRHIDCA+VY NE EVGE I + Sbjct: 6 VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 KI EGVV REDLF+TSKLWNTFHRPDLV GA + TL NL + YLDLYLIHWP Y+E Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125 Query: 407 LFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 LFP GK FSD DYVDTW ME LV GLV++IGVSNFN+KQ++R+L A + P Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPAT 185 Query: 584 NQVECHPYLNQKRLKEF 634 NQ+ECHPYL+Q ++ F Sbjct: 186 NQIECHPYLHQSKITTF 202 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 269 bits (659), Expect = 4e-71 Identities = 121/193 (62%), Positives = 148/193 (76%), Gaps = 1/193 (0%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P ++G +P+ GLGTW+S P V QAVKDAIDIGYRH DCA++YGNE VG AI K Sbjct: 4 PSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIREK 63 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 I+EG+VTR++LFITSKLWNTFH+P+LVR A + +L NL + YLDLYL+HWP AYK +L Sbjct: 64 IQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGDNL 123 Query: 410 FPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 +PT +GK F D+DY+DTWKAME LV GLV +IGVSNFN KQ+ RLL A +KPV+ Sbjct: 124 YPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPVML 183 Query: 587 QVECHPYLNQKRL 625 Q+ECHPYL QK L Sbjct: 184 QIECHPYLRQKSL 196 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 264 bits (647), Expect = 1e-69 Identities = 120/194 (61%), Positives = 151/194 (77%), Gaps = 2/194 (1%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P +NG+ +P+ GLGTW+S P VTQAVKDAIDIGYRH DCA++YGNE +VG A+ K Sbjct: 4 PNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREK 63 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE-DGS 406 + EGVVTR++LFITSKLWNT H+PDLVR A + ++ NL V+YL+LYL+HWP AYK + Sbjct: 64 MDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDN 123 Query: 407 LFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 L+PT + K F D+DYVDTW+AME LV EGL ++IGVSNFN +Q+ RLL A +KPVV Sbjct: 124 LYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVV 183 Query: 584 NQVECHPYLNQKRL 625 Q+ECHPYL+QK L Sbjct: 184 LQIECHPYLSQKPL 197 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 259 bits (635), Expect = 3e-68 Identities = 120/192 (62%), Positives = 143/192 (74%), Gaps = 2/192 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NNG +P GLGTWKS PG+VT+AVK AID+GYRHIDCA VY NEKEVG A+ K+KE V Sbjct: 8 NNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQV 67 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 V R+DLFI SKLW TFH +V+GA Q+TL +L + YLDLYLIHWP +K FP D Sbjct: 68 VKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDA 127 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVEC 598 SG + SD D+VDTW AME LV EGLVK+IGVSNFN Q+ER+L + KP VNQ+EC Sbjct: 128 SGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIEC 187 Query: 599 HPYLNQKRLKEF 634 HPYL Q++L E+ Sbjct: 188 HPYLTQEKLIEY 199 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 252 bits (616), Expect = 7e-66 Identities = 114/192 (59%), Positives = 143/192 (74%), Gaps = 2/192 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NNG +P+ GLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP +K FP D+ Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVEC 598 SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E +L + KP VNQ+EC Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187 Query: 599 HPYLNQKRLKEF 634 HPYL Q++L ++ Sbjct: 188 HPYLTQEKLIQY 199 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 243 bits (594), Expect = 3e-63 Identities = 114/195 (58%), Positives = 137/195 (70%), Gaps = 2/195 (1%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 VT G +P+ GLGTWKS P +V +AVK AID GYRHIDCAYVY NE EVGEAI KI+ Sbjct: 5 VTLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ 64 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 E V REDLFI SKLW+TF LV+ A Q TL +L + YLDLYLIHWPQ ++ P Sbjct: 65 EKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLP 124 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQ 589 TD G I S ++D W+AME LV +GLVK++GVSNFN Q+ERLL + KPV NQ Sbjct: 125 TDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQ 184 Query: 590 VECHPYLNQKRLKEF 634 VECHPYL Q++L ++ Sbjct: 185 VECHPYLTQEKLTQY 199 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 242 bits (592), Expect = 6e-63 Identities = 108/196 (55%), Positives = 145/196 (73%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 +P VTFN+G +P+ GLGT+ SKPGEV +AVK AI++GYRH+D A+ Y NEKE+G AI Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 KI +G + RED+F+T+KLW H+ D V A +++L+NL Y+DL+L+HWP A+K + Sbjct: 63 KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 L P D +GKI+FSD DY++TWK ME ++GL +SIG+SNFNS+Q+ RLL A +KPV N Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNN 182 Query: 587 QVECHPYLNQKRLKEF 634 QVE LNQK L EF Sbjct: 183 QVEVTMNLNQKPLIEF 198 Score = 167 bits (406), Expect = 2e-40 Identities = 84/159 (52%), Positives = 109/159 (68%), Gaps = 1/159 (0%) Frame = +2 Query: 161 YRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDN 340 YRHID AY+Y NEK +G AI KIK+G V REDLF+T+KL H+ V A +++L++ Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360 Query: 341 LNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 517 L + Y+DLYLIHWP + Y + SGK+ SD DY++TWK ME ++GL +SIG Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQGLARSIG 416 Query: 518 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 VSNFNS+Q+ RLL+ A +KPV NQVE LNQK L EF Sbjct: 417 VSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEF 455 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 230 bits (563), Expect = 2e-59 Identities = 103/190 (54%), Positives = 132/190 (69%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N+G +IP GLGTW+SKPGEV A+K A+ GYRHIDCA+VY N+KEVGEA+ + EG Sbjct: 8 NSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEGK 67 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 V RE+LFITSK+WNTFH + L +L + Y+DL LIHWPQ Y E LFP + Sbjct: 68 VKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAGE 127 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 +GK+++SDVDY++TWKA E K G +SIG+SNF Q++R+ A VKP QVE HP Sbjct: 128 NGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHP 187 Query: 605 YLNQKRLKEF 634 Y Q +L+EF Sbjct: 188 YFTQVKLREF 197 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 229 bits (560), Expect = 4e-59 Identities = 101/191 (52%), Positives = 140/191 (73%), Gaps = 1/191 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 V + G+ +P+ GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65 Query: 236 EG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A++ + F Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 P + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q++ +L A+V+P V QV Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQV 185 Query: 593 ECHPYLNQKRL 625 ECHPYL Q L Sbjct: 186 ECHPYLAQNEL 196 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 226 bits (553), Expect = 3e-58 Identities = 108/205 (52%), Positives = 147/205 (71%), Gaps = 5/205 (2%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 M+ ++P V F+NG IPV G GT+ ++ G+ + VK AID+GYRHID A++Y NE E+G+ Sbjct: 1 MSTQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQ 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 AI KI EGV+ RED+F+T+KLWNTFH P V A + + D L++ Y+DL+L+H P + Sbjct: 61 AIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQ 120 Query: 395 EDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE-GLVKSIGVSNFNSKQLERLLQ 559 G + P D +G + FSDVDYV+TWKAME LV G V+SIG+SNFNS+Q+ER+LQ Sbjct: 121 FSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQ 180 Query: 560 HATVKPVVNQVECHPYLNQKRLKEF 634 ATVKPV NQVE +P +Q++L F Sbjct: 181 IATVKPVNNQVEANPGYDQRKLIAF 205 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 226 bits (553), Expect = 3e-58 Identities = 114/200 (57%), Positives = 139/200 (69%), Gaps = 4/200 (2%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP V NNG +P GLGT SK E +AV AID G+RHID AY Y NE VG AI + Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 403 KI+EGVVTRE+LF+T+KLWNTFH PD V A ++L++L + Y+DL+LIH P Y+ +G Sbjct: 66 KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125 Query: 404 ---SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 P D +G + SD DYVDTWKAME L++ G V SIGVSNFNS+QLER+L + VK Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVK 185 Query: 575 PVVNQVECHPYLNQKRLKEF 634 PV NQVEC +NQK L EF Sbjct: 186 PVTNQVECSARINQKLLIEF 205 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 223 bits (546), Expect = 2e-57 Identities = 102/202 (50%), Positives = 139/202 (68%), Gaps = 2/202 (0%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 208 M+PK+ +T ++G +PV GLGTW+ + P EV AVK AID GYRH DCA YGNE E+ Sbjct: 1 MSPKVDEITLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEI 60 Query: 209 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388 G+AI KI +GVV REDLF+ +K+WN + +LV A + +L L + Y+DLYL+HWP + Sbjct: 61 GKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFS 120 Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 Y + +VDY++TW+ ME +K GL +SIGVSNFNS+QL RLL+ A+ Sbjct: 121 YPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESAS 180 Query: 569 VKPVVNQVECHPYLNQKRLKEF 634 +KPV+NQ+E H LNQK+L+EF Sbjct: 181 IKPVMNQIELHINLNQKKLREF 202 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 121 bits (291), Expect(2) = 4e-55 Identities = 57/87 (65%), Positives = 67/87 (77%), Gaps = 2/87 (2%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 M+PK P+V NNG +PV GLGTW SK GE +A+K AID GYRHID AY Y NEKEVGE Sbjct: 1 MSPKAPMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGE 60 Query: 215 AITSKIKEGVVTREDLFITSKL--WNT 289 AI +KI+EGVV REDLF+T+K W+T Sbjct: 61 AIRAKIEEGVVCREDLFVTTKFIDWDT 87 Score = 116 bits (280), Expect(2) = 4e-55 Identities = 52/77 (67%), Positives = 62/77 (80%) Frame = +2 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 +L P D GK+QFSDVDY+DTWKAME L+K G VKSIGVSNFNS+Q+ RLL +KPV Sbjct: 89 NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148 Query: 584 NQVECHPYLNQKRLKEF 634 NQVEC+P LNQ++L EF Sbjct: 149 NQVECNPSLNQRKLTEF 165 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 216 bits (527), Expect = 4e-55 Identities = 103/198 (52%), Positives = 134/198 (67%), Gaps = 5/198 (2%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTW---KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 V N+G +PV G GT+ K + K AID+GYRHIDCA++YGNE+EVG AI + Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRA 68 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 KI +G V RED+F T KLW+T H P+ VR AL+++L +L + Y+DL++IH P +K Sbjct: 69 KIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDD 128 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPV 580 LFP D++GK + + D DTWKA+E GLV+SIGVSNFN KQLE +L + KPV Sbjct: 129 LFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPV 188 Query: 581 VNQVECHPYLNQKRLKEF 634 NQVECH YLNQ +L EF Sbjct: 189 CNQVECHVYLNQSKLLEF 206 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 215 bits (525), Expect = 7e-55 Identities = 99/195 (50%), Positives = 133/195 (68%), Gaps = 2/195 (1%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 VT +G +P+ GLGTWK K EV A+ A+D GYRH DCA +YGNEKEVG A+ ++ Sbjct: 5 VTLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQ 64 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 409 + RED+FIT+K+WNTFH + V +L +L + Y+DLY++HWP ++ G + Sbjct: 65 RLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVM 124 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 FP ++G I +SDV Y++TW AME LVK G KS+G+SNFNSKQL+ +LQH+TV P V Q Sbjct: 125 FPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQ 184 Query: 590 VECHPYLNQKRLKEF 634 VE HP+L Q L F Sbjct: 185 VESHPFLPQVELLNF 199 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 215 bits (525), Expect = 7e-55 Identities = 103/202 (50%), Positives = 139/202 (68%), Gaps = 5/202 (2%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKE 205 M KI + N+G +IPV G GT+ ++ + ++ K AID+G+ HIDC+++Y NE+E Sbjct: 1 MNSKIQKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEE 60 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 +G+AI SKI++G V RED+F TSKLW+T HRP+LVR +L+ +L LN+ Y+DLYLIH+P Sbjct: 61 IGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPV 120 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 + K L P D+ G + F VD DTW+AME GL KSIGVSNFN +QLE +L Sbjct: 121 SLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 566 TV--KPVVNQVECHPYLNQKRL 625 + KPV NQVECH YLNQ +L Sbjct: 181 GLKYKPVCNQVECHLYLNQSKL 202 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 214 bits (522), Expect = 2e-54 Identities = 110/206 (53%), Positives = 133/206 (64%), Gaps = 21/206 (10%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 IP GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V RED Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63 Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL-- 409 LFI +KLW T H+ LV A +++L L + YLDLYLIHWP +K L Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123 Query: 410 ---------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 P D+S + SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183 Query: 563 ATV--KPVVNQVECHPYLNQKRLKEF 634 + KP+ NQ+ECHPYL QK L F Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISF 209 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 213 bits (519), Expect = 4e-54 Identities = 100/193 (51%), Positives = 130/193 (67%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 +T N +T+P+ G GTW+ G V+ AI GYRHIDCA +YGNEKEVGE I I Sbjct: 4 LTLRNKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTID 63 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 +GVV REDLF+TSKLWNT H V A ++TL++L + YLDLYLIHW A++ +L P Sbjct: 64 QGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEP 123 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 D G +FS + +TW+AME LV++GLVKS+GV+NF + L LL +A +KP V+Q+E Sbjct: 124 LDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIE 183 Query: 596 CHPYLNQKRLKEF 634 HPYL Q L F Sbjct: 184 LHPYLAQNDLVAF 196 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 212 bits (517), Expect = 7e-54 Identities = 96/194 (49%), Positives = 134/194 (69%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P + NNG +P GLGTWKS + + + A+D+GYRH+D A+VY NE EVG+AI+ K Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEK 65 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 I EGVVTRE++F+T+KL H P LV A + +L NL ++Y+DLYL+H P K Sbjct: 66 IAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHND- 124 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 ++ G ++ +DVDY+DTW+ ME LV GL +SIG+SNFN+ Q ER+L + ++PVVNQ Sbjct: 125 --SNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQ 182 Query: 590 VECHPYLNQKRLKE 631 VECHP Q++L+E Sbjct: 183 VECHPGFQQRQLRE 196 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 211 bits (515), Expect = 1e-53 Identities = 106/196 (54%), Positives = 134/196 (68%), Gaps = 1/196 (0%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P ++G IP+ G GTWK++ V +AV+ A+D GYRHIDCA VY NEKEVGEA T K Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62 Query: 230 IK-EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 E V RED+FITSKLWNTFH+ + VR AL+ TL +L +QYLDLYL+HWP A++ + Sbjct: 63 FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 T SG Q V +TW+ ME LV GLVKSIG+SNFN + L +L +A +KP N Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAAN 179 Query: 587 QVECHPYLNQKRLKEF 634 QVE HP+L+Q LK+F Sbjct: 180 QVELHPFLSQPELKKF 195 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 211 bits (515), Expect = 1e-53 Identities = 105/200 (52%), Positives = 135/200 (67%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MA K N G +IP LGTW+S EV AV+ AI++GYRHIDCA +YGNE E+GE Sbjct: 1 MAMKQIFCKLNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGE 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 A++ + EG V RE+LF+TSKLW H PD V A Q TL NL + YLDLYLIH P A+K Sbjct: 61 ALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFK 120 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 + L + G I ++ +TW+AME LV +GL K+IGVSNF+ K+L +LL+ A++ Sbjct: 121 KGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIV 180 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P NQVE HPYL Q++LKEF Sbjct: 181 PACNQVELHPYLPQEKLKEF 200 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 207 bits (506), Expect = 1e-52 Identities = 107/222 (48%), Positives = 139/222 (62%), Gaps = 26/222 (11%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP VT N G +PV GLGTWKS G T+AVK AI GYRHID AYVY NE EVG + + Sbjct: 2 IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ------- 385 I +GVV RE+LFI SKLW TFH P LVRGA ++TL +LN+ Y+DLYL+H+P Sbjct: 62 MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121 Query: 386 -----------AYKEDGSL------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 514 +++ L FP D+ ++ ++DTW+AME LV +GL K+I Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAI 181 Query: 515 GVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEF 634 G+SNFN Q+E +L + KP NQ+ECHP+LNQ++L F Sbjct: 182 GISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHF 223 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 207 bits (506), Expect = 1e-52 Identities = 101/205 (49%), Positives = 139/205 (67%), Gaps = 5/205 (2%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDA---IDIGYRHIDCAYVYGNEKE 205 M+ K V N+G IP G GT+K K +++++ A +D+GYRH+D AY Y E+E Sbjct: 1 MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEE 60 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 +G+AI SKIK GVV REDLFIT+KLW T RP+LV+ AL+++L L + Y+DLY++H+P Sbjct: 61 IGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPV 120 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 K + FP ++ GK VD+ DTW+ +E GLVKSIGVSNFN +QLER+L Sbjct: 121 PMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKP 180 Query: 566 TV--KPVVNQVECHPYLNQKRLKEF 634 + KPV NQVECH YLNQ++L ++ Sbjct: 181 GLKYKPVCNQVECHLYLNQRKLLDY 205 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 206 bits (504), Expect = 3e-52 Identities = 100/192 (52%), Positives = 127/192 (66%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T N G IP G GTW++KP EV AV+ A+ GYRHIDCA +Y NE EVG I K Sbjct: 8 TINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR---KS 64 Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 GV RE++FIT KLWNT H P+ V AL +TL +L V YLDLYL+HWP A+K FP Sbjct: 65 GV-PREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPL 123 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 + G +++DY+ T++AME L+ G V++IGVSNFN ++LE LL +V P VNQ+E Sbjct: 124 NDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEA 183 Query: 599 HPYLNQKRLKEF 634 HPYL Q L +F Sbjct: 184 HPYLQQPDLLQF 195 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 205 bits (501), Expect = 6e-52 Identities = 95/193 (49%), Positives = 127/193 (65%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 ++F NG+ +P+ GLGTWKS PGEV +AV A++ GYRH+DCA +Y NE EVG A++ Sbjct: 4 ISFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFD 63 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 G + R+D+++TSKLWN H PD VR AL++TL +L + LDLYLIHWP A + + FP Sbjct: 64 AGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVD-FP 122 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 + V +TW AME L K+GLV+ IGVSNF+ L+ +L V+P +NQVE Sbjct: 123 ESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVE 182 Query: 596 CHPYLNQKRLKEF 634 HPYL Q L F Sbjct: 183 MHPYLPQPELVSF 195 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 202 bits (493), Expect = 6e-51 Identities = 96/181 (53%), Positives = 124/181 (68%), Gaps = 2/181 (1%) Frame = +2 Query: 98 GTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK 277 GT KS +V A K A+D+GYRH+D A++Y +E VG+A K +G + REDLF TSK Sbjct: 47 GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106 Query: 278 LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY 457 LWNTFH+P LVR AL++TL L + Y+DLYLIH P ++K LFP ++ G F D Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166 Query: 458 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKE 631 + TW+A+E GLVKSIGVSNFN +QLE +L + KPV NQ+ECHPYLNQK++ E Sbjct: 167 LQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLE 226 Query: 632 F 634 F Sbjct: 227 F 227 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 198 bits (484), Expect = 7e-50 Identities = 102/200 (51%), Positives = 126/200 (63%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MA I N G P GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 + ++ VV REDLFITSKLW T H P V AL TL +L ++Y+DLYLIHWP K Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 + GS+ ++ VD TWKAME L G ++IGVSNF++K+L LL+ A V Sbjct: 121 K-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVP 175 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P VNQVECHP Q +L+EF Sbjct: 176 PAVNQVECHPSWRQTKLQEF 195 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 198 bits (484), Expect = 7e-50 Identities = 102/200 (51%), Positives = 126/200 (63%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MA I N G P GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 + ++ VV REDLFITSKLW T H P V AL TL +L ++Y+DLYLIHWP K Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 + GS+ ++ VD TWKAME L G ++IGVSNF++K+L LL+ A V Sbjct: 121 K-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVP 175 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P VNQVECHP Q +L+EF Sbjct: 176 PAVNQVECHPSWRQTKLQEF 195 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 197 bits (481), Expect = 2e-49 Identities = 93/200 (46%), Positives = 126/200 (63%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MA + N GE IP G GTW+ + + AV A+ GYRHID A VYG EK +G Sbjct: 1 MASRHTTFRLNTGEDIPAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGR 59 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 A+ ++R++LFITSKLWN HRP+ V A+ ++L NL + YLDLYL+HWP A+ Sbjct: 60 ALA----RSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFA 115 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 +FP D G + D+DYVDT+KAME LVK G K+IG+SNF+ ++ERLL+ ++ Sbjct: 116 PGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIV 175 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P V Q+E HP+L Q E+ Sbjct: 176 PAVMQMELHPWLQQNDFVEW 195 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 197 bits (480), Expect = 2e-49 Identities = 100/196 (51%), Positives = 131/196 (66%), Gaps = 6/196 (3%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 N+G IP GLGT+ S+ PGEV A+ +A+ GYRHID A YGNEK +G ++ KEG Sbjct: 20 NDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEG 79 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT- 418 + RED+F TSKLWN+ H +LV +T+++L + YLDLYLIHWP A++ L T Sbjct: 80 EIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTI 139 Query: 419 ----DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 DQ+G + V +TW+ ME LV+ GLVKSIGVSNFN + L LL +A +KPVVN Sbjct: 140 EPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVN 199 Query: 587 QVECHPYLNQKRLKEF 634 QVE HPYL Q +L+E+ Sbjct: 200 QVEIHPYLTQFKLQEY 215 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 197 bits (480), Expect = 2e-49 Identities = 100/199 (50%), Positives = 129/199 (64%), Gaps = 6/199 (3%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 + ++G +IP+ GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 KI EG V RED+F KLW T H P++VR L+ TL L + Y+DLY+I P A+K Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KP 577 ++P D++GK + + TW+AME GLVKS+GVSNFN +QLE +L + KP Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189 Query: 578 VVNQVECHPYLNQKRLKEF 634 V NQVECHPY Q +L +F Sbjct: 190 VSNQVECHPYFTQPKLLKF 208 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 196 bits (479), Expect = 3e-49 Identities = 99/198 (50%), Positives = 129/198 (65%), Gaps = 5/198 (2%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 + T N G ++ + G GTW++ PGEV Q VK AI+ GYRH+D A VY N+ EVG AI Sbjct: 2 VGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAI-- 59 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 403 KE V REDLFITSKLWN HRP+ V AL +TL L ++YLDLYLIHWP A+ +G Sbjct: 60 --KEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGD 117 Query: 404 ---SLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571 +LFP +++ +V VDTWKAM L+ G VK+IGVSNF++K ++ +++ V Sbjct: 118 ITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGV 177 Query: 572 KPVVNQVECHPYLNQKRL 625 P VNQ+E HP L Q L Sbjct: 178 TPSVNQIERHPLLLQPEL 195 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 196 bits (477), Expect = 5e-49 Identities = 93/191 (48%), Positives = 124/191 (64%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T +G IP GLGTW+S+P + AVK A+ GYRHID A +YGNE EVG+ I KE Sbjct: 17 TLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGI----KE 72 Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 V R+D+++TSKLW H P+ V AL++TL +L + YLD YLIHWP ++K FP Sbjct: 73 SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPK 132 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 D+ G + + +TWKAME L++ G V+ IG+SNFN LER+L+ A VKP V+Q+E Sbjct: 133 DKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMEL 192 Query: 599 HPYLNQKRLKE 631 HP+L Q E Sbjct: 193 HPFLPQTEFVE 203 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 194 bits (474), Expect = 1e-48 Identities = 96/202 (47%), Positives = 128/202 (63%), Gaps = 2/202 (0%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MA + G +P+ G GTW+ KP EV + ++ AID GYRHID A +YGNEK VG+ Sbjct: 1 MASSNTHIVLPGGRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGD 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 I +KI +G + REDLF+TSKLW T P V + +++L +L + YLDL+LIH P + Sbjct: 61 GIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAV 120 Query: 395 EDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571 FP D +G D +DYVDTW+ ME LV +GLV++IGVSNF Q++R+L Sbjct: 121 GGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPK 180 Query: 572 KPVVN-QVECHPYLNQKRLKEF 634 P+ N QVECHP+L Q L EF Sbjct: 181 YPIANVQVECHPFLAQNELIEF 202 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 194 bits (472), Expect = 2e-48 Identities = 95/192 (49%), Positives = 127/192 (66%), Gaps = 2/192 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N G +P GLGTW+SK EV AV A+ GYRHID A VYGNE+EVG+ + + Sbjct: 10 NTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM----RLSG 65 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP--T 418 V RE++F+TSKLWNT H P+ V A+ ++L +L YLDLYLIHWP A++ + Sbjct: 66 VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPVN 125 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 +Q+G I DV DTW AME LV++G V+SIGVSNF +++E LL+ A + P VNQ+E Sbjct: 126 EQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIEA 185 Query: 599 HPYLNQKRLKEF 634 HP+L Q+ L E+ Sbjct: 186 HPFLQQRDLLEW 197 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 193 bits (471), Expect = 3e-48 Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 4/179 (2%) Frame = +2 Query: 83 PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 256 P G GTW++ P V AV+ A+ GYRHIDCAYVY NE+ +G A K+ + RE Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--GSLFPTDQSG 430 D++ITSKLWN HRP+LVR ++T+ +L V YLDL+L+HWP A+ + G LFP D G Sbjct: 65 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607 + V DTW+AME LV+EGLVK IGVSN+ L LL +A +KP+VNQ+E HP+ Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPW 183 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 191 bits (465), Expect = 1e-47 Identities = 100/192 (52%), Positives = 123/192 (64%), Gaps = 21/192 (10%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 IP GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V RED Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63 Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL-- 409 LFI +KLW T H+ LV A +++L L + YLDLYLIHWP +K L Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123 Query: 410 ---------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 P D+S + SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183 Query: 563 ATV--KPVVNQV 592 + KP+ NQ+ Sbjct: 184 PGLRFKPLTNQI 195 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 190 bits (464), Expect = 2e-47 Identities = 99/192 (51%), Positives = 125/192 (65%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T NNG IP GLGTW S GEV +AV+ AI GYRHIDCA YGNEKEVG+ I S I + Sbjct: 6 TLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAK 65 Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 G V RE+LF+T+KLW+T + VR A E+L L ++YLDLY+IH P L Sbjct: 66 GYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIP--------LTAD 117 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 ++G+ + +TW+ ME LV+EGLVKSIGVSNFN K+LE LL A ++P VNQ E Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177 Query: 599 HPYLNQKRLKEF 634 H Y + +L +F Sbjct: 178 HIYYQRPKLHQF 189 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 190 bits (463), Expect = 2e-47 Identities = 90/191 (47%), Positives = 121/191 (63%) Frame = +2 Query: 62 FNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 F +G++IP GLGTWKS P +V +AVK A++ GY+HIDCA Y NE VGEA + G Sbjct: 6 FRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESG 65 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 V RED+F+TSKLWN H+ + V AL++TL +LN+ YLDLYL+HWP A+K + FP Sbjct: 66 NVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFPEK 125 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 + + +T AM K+GL+K +GVSNF+ ++LE L P +NQVE H Sbjct: 126 DEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVELH 185 Query: 602 PYLNQKRLKEF 634 PYL Q L + Sbjct: 186 PYLPQNDLYSY 196 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 189 bits (461), Expect = 4e-47 Identities = 92/203 (45%), Positives = 129/203 (63%) Frame = +2 Query: 26 ISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205 I + P + + +NG+ +P+ GLGT KS+ +V ++V++AI IGYRHIDCA +YGNE+E Sbjct: 12 IKDVIPTMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEE 71 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 VG+AI I+ +TR +L+ITSKLW+ H + V AL ++L NL V YL+LYLIHWP Sbjct: 72 VGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPV 131 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 + + F + + +TW+AME +GL K IGVSNF K+L++L+ H Sbjct: 132 GIRPE-KTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHC 190 Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634 KP VNQVE HP L Q L E+ Sbjct: 191 KQKPEVNQVEHHPLLQQPTLIEY 213 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 184 bits (449), Expect = 1e-45 Identities = 94/204 (46%), Positives = 128/204 (62%), Gaps = 10/204 (4%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 +VT NNG +P+ GLG WK + +AI +GYR D A YGNEKEVGE I I Sbjct: 4 LVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK--EDGS 406 EG+V+R+D+F+ SKLWN FH PD V+ AL++TL ++ + YLDLY IH+P A+K Sbjct: 64 SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123 Query: 407 LFP--------TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 +P ++ G I + V +DT++A+E V EGL+KSIGVSNF ++ LL+ Sbjct: 124 KYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRG 183 Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634 +KPV Q+E HPYL Q+ L EF Sbjct: 184 CRIKPVALQIEHHPYLTQEHLVEF 207 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 184 bits (448), Expect = 2e-45 Identities = 91/192 (47%), Positives = 123/192 (64%), Gaps = 2/192 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N+G IP GLGTW SKP EV AV+ A+ GYRHID A Y NE EVG K+ Sbjct: 10 NSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGW----KKSG 65 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE-DGSLFPTD 421 V R+ +FITSKLWNT H P+ V A+ +TL +L YLDLYLIHWP A++ + +L P D Sbjct: 66 VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPID 125 Query: 422 Q-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 + + + ++V DTW A+E LV+ ++SIG+SNF +++ LL+ A + P VNQ+E Sbjct: 126 PVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIEA 185 Query: 599 HPYLNQKRLKEF 634 HPYL Q L ++ Sbjct: 186 HPYLQQPGLHKY 197 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 182 bits (444), Expect = 5e-45 Identities = 94/202 (46%), Positives = 119/202 (58%), Gaps = 2/202 (0%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MAP +V NG IP GLGTWK++P EV AV+DA+ GY H+DCA Y NE EVGE Sbjct: 1 MAPSTILVNDANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGE 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 A+ + G RED+F+TSKLWN RP VR AL TL++L V YLDLYLIHWP A+K Sbjct: 61 ALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWK 120 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ--HAT 568 G++ D I + W +E V +GLV+ IGVSNFN QL L Sbjct: 121 R-GTVLQPDAEASI-------AECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTK 172 Query: 569 VKPVVNQVECHPYLNQKRLKEF 634 ++P NQ+E HP + L ++ Sbjct: 173 IQPACNQIESHPLWSNDSLVKY 194 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 182 bits (443), Expect = 6e-45 Identities = 91/193 (47%), Positives = 119/193 (61%), Gaps = 3/193 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 NNG+ IP GLGTW + V + A+++A+ +GYRHID A++YGNEK +G + EG Sbjct: 9 NNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEG 68 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFP 415 VV R+DLFITSKLWNTFH L+ +L++L + Y+DLYLIHWP + DG++ Sbjct: 69 VVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVES 126 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 + K D V WK ME LV GL KSIG+SNF E++L + P Q+E Sbjct: 127 CGK--KYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIE 184 Query: 596 CHPYLNQKRLKEF 634 HPYLNQK L EF Sbjct: 185 LHPYLNQKELVEF 197 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 180 bits (437), Expect = 3e-44 Identities = 94/196 (47%), Positives = 119/196 (60%), Gaps = 4/196 (2%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T N G IP FGLGTW+ G + +AV AI GYR ID AYVYGNE+EVG+ I I Sbjct: 7 TLNTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISS 66 Query: 239 GVVTREDLFITSKLWNTF-HRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 409 G+V REDLF+ SK W T+ R +L L ++L L + Y+DLYL+HWP +G+ Sbjct: 67 GIVKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEK 123 Query: 410 FPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 FP G ++VDTWK ME L G K++GVSN++ LE+LL HAT P VN Sbjct: 124 FPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVN 183 Query: 587 QVECHPYLNQKRLKEF 634 QVE HP L Q+ L +F Sbjct: 184 QVENHPQLPQQELVDF 199 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 177 bits (430), Expect = 2e-43 Identities = 90/193 (46%), Positives = 127/193 (65%), Gaps = 6/193 (3%) Frame = +2 Query: 74 ETIPVFGLGTWKSK-PGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 E IP GLGT+ ++ P + AV AI D GYRH+DCA Y N++ +GEA++ +G V Sbjct: 2 EVIPSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQV 61 Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFPTD 421 RE+++ITSK+WNT HRPDL+ +++TL L ++YLDL L+HW A+ +ED P D Sbjct: 62 KREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRD 121 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVE 595 ++GKI ++D ++TWKAME GL K IGVSNF+ +QLER+ VK P NQVE Sbjct: 122 ETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVE 181 Query: 596 CHPYLNQKRLKEF 634 H YL Q+ + ++ Sbjct: 182 SHMYLQQQPMLDY 194 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 176 bits (429), Expect = 3e-43 Identities = 92/190 (48%), Positives = 124/190 (65%), Gaps = 1/190 (0%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE-AITSKIKEG 241 NNG+ +P GLGTW + PGEV +AV A++ GYR IDCA Y NEKE+GE I +K Sbjct: 9 NNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKNH 68 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 RE+LF+TSKLW + +R + E++ +L +YLDLYLIHWP A K D S P Sbjct: 69 --PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKP 124 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 + F D+D + W+ ME LV EGLVKSIG+SNF Q+E++++ +KPV+NQVE + Sbjct: 125 ED----FLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELN 180 Query: 602 PYLNQKRLKE 631 YL Q +L+E Sbjct: 181 VYLQQNKLRE 190 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 176 bits (429), Expect = 3e-43 Identities = 84/193 (43%), Positives = 127/193 (65%), Gaps = 2/193 (1%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 + N G +P+FGLGTW+ K E+T A++ A+D GYR ID A++Y NE +G+ + I Sbjct: 6 IPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYI 65 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK-EDGSL 409 G + RED+F+TSKL T H P+ V ++ L L ++Y+DLYLIH P +K ++GS Sbjct: 66 SSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSF 125 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 P ++G++ +++ ++DTW+A+E L KEG +K++GVSNF+ QL+ L A VKP Q Sbjct: 126 APLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQQ 185 Query: 590 VECHPYLNQKRLK 628 VECH Y Q+ L+ Sbjct: 186 VECHIYWPQQELR 198 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 176 bits (428), Expect = 4e-43 Identities = 81/203 (39%), Positives = 126/203 (62%), Gaps = 5/203 (2%) Frame = +2 Query: 41 PKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 220 P VT N+G +PV G GTW+ + V+DA++ GYRHID A + N++EV I Sbjct: 2 PIADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGI 61 Query: 221 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 400 K V RE+LF++SK+WNT+H + + E L+ Y+DL +IHWP + ED Sbjct: 62 KDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAED 121 Query: 401 -----GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 L+P +GK+++SDVDY++TWKA+E + G ++SIG++NFN Q+E++ Sbjct: 122 EPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTKG 181 Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634 +KP V QVE +P+L+Q+ +++F Sbjct: 182 LIKPAVLQVEMNPFLDQEEIRQF 204 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 175 bits (427), Expect = 6e-43 Identities = 84/169 (49%), Positives = 115/169 (68%), Gaps = 1/169 (0%) Frame = +2 Query: 131 QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLV 310 +A + AI GYRHID A+ Y NE +VG AI +KI++G++ R+D+FI SKLW T H P+ + Sbjct: 4 RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63 Query: 311 RGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPL 487 ++L +L + YLD YL+H+P K+ G LFP ++ GKI +D+DYVD W+ ME L Sbjct: 64 PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122 Query: 488 VKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 G VKSIGVSNF +Q++RLL A + P VNQVE HPYL Q L ++ Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDY 171 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 175 bits (426), Expect = 7e-43 Identities = 88/205 (42%), Positives = 132/205 (64%), Gaps = 9/205 (4%) Frame = +2 Query: 38 APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217 A ++P V ++ +++P GLG WK QAV +AI +GYRH+D A YGNE++VGE Sbjct: 4 AIQVPGVKVSS-KSMPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEG 62 Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--Y 391 I I EG+ +RE+L+IT+KLWNT+HR + V A + ++D+L + Y+DLYL+H+P A Y Sbjct: 63 IARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRY 122 Query: 392 KEDGSLFPT----DQSGKIQFSDVDYV---DTWKAMEPLVKEGLVKSIGVSNFNSKQLER 550 + +P D S + ++D V +TW AME LV+ GLV+ IGV N+++ L Sbjct: 123 VDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHD 182 Query: 551 LLQHATVKPVVNQVECHPYLNQKRL 625 L+ +A +KP + Q+E HPYL Q+ L Sbjct: 183 LMSYARIKPAMLQIESHPYLTQEAL 207 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 175 bits (426), Expect = 7e-43 Identities = 86/196 (43%), Positives = 127/196 (64%), Gaps = 3/196 (1%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 +TFNNGE +PV G+GTW++ E+ A+ A++ GYRHID A VYGNEK +G + + Sbjct: 7 LTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDGSL 409 G V RE+LFI +K+ +RP V ++++L++L + Y+DLYL+H P EDGS Sbjct: 67 AGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGS- 125 Query: 410 FPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 F D+ G ++ ++ W AME LV++GL KSIGVSNF+ Q+ RLL++ ++P N Sbjct: 126 FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANN 185 Query: 587 QVECHPYLNQKRLKEF 634 Q+E H YL Q+ L +F Sbjct: 186 QIEHHVYLQQRDLVDF 201 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 174 bits (424), Expect = 1e-42 Identities = 89/202 (44%), Positives = 123/202 (60%), Gaps = 9/202 (4%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTW---------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNE 199 +P++ N +P LGT+ SK ++ V AID+GYRH D A +Y E Sbjct: 22 VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81 Query: 200 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 379 EVGEAI KI EGV+ RED+F+T+KLWNT H+ + V A++ETL+ + Y+DL+L+HW Sbjct: 82 AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141 Query: 380 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 559 P A ED S S+ DY++TW+A E +VK G KSIG+SNFN Q+ +LQ Sbjct: 142 PIALNEDYS-----------HSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQ 190 Query: 560 HATVKPVVNQVECHPYLNQKRL 625 T+KPV Q+E HP + Q+ L Sbjct: 191 ECTIKPVALQIEVHPQIIQEDL 212 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 174 bits (424), Expect = 1e-42 Identities = 84/173 (48%), Positives = 122/173 (70%), Gaps = 2/173 (1%) Frame = +2 Query: 122 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRP 301 + + AV AI+ G+RH D AY Y NEKE+GEA+ ++IK G ++RE++F+T+KLWNT H P Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104 Query: 302 DLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKA 475 VR ++ L+ L Y+DLYL+H+P YK D L P ++Q ++DY+DTW+A Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPM-SGDELQTVEIDYLDTWRA 163 Query: 476 MEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 ME LVK G+V+SIG+SNFN +Q++R++Q ++ KPVVNQVE P QK L ++ Sbjct: 164 MENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDY 216 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 173 bits (422), Expect = 2e-42 Identities = 89/200 (44%), Positives = 117/200 (58%), Gaps = 7/200 (3%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 VT N+G IP G GTW+S PG+V AV +A+ GYRH+D A +Y N++EV E I K Sbjct: 7 VTLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYK 66 Query: 236 EGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 + + RED+FITSKLWN+ H P +V AL E L L + YLDLYL+HWP ++ LF Sbjct: 67 DVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELF 126 Query: 413 PTDQSGKIQFSDV------DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 P + ++ DV VDTWKAM L K +++GVSN LE ++ V Sbjct: 127 PLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAIINATGVV 185 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P VNQ+E HP L L E+ Sbjct: 186 PAVNQIERHPVLQSNELIEY 205 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 172 bits (419), Expect = 5e-42 Identities = 85/196 (43%), Positives = 128/196 (65%), Gaps = 2/196 (1%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 ++ NNG +IP GLGT+K + A+K A++ GYR ID A+VY NE+ VG+A+ Sbjct: 1 MLALNNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIF 60 Query: 233 KEGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 +G + RED+FI SKL TFHRP+ V + +L+ L + Y+DLYL+H P A ++ G Sbjct: 61 SQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSG-- 118 Query: 410 FPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 D + + + D V ++TWKA+E ++GLV+SIGVSNFN +QL ++ H +++PVVN Sbjct: 119 ---DGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVN 175 Query: 587 QVECHPYLNQKRLKEF 634 QVEC +Q +L++F Sbjct: 176 QVECSIGFHQVKLRKF 191 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 171 bits (417), Expect = 9e-42 Identities = 96/195 (49%), Positives = 124/195 (63%), Gaps = 10/195 (5%) Frame = +2 Query: 80 IPVFGLGTWKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 IP GLGTWKS E +T A+K+A GY HIDCA Y NE VG+A+ G+ Sbjct: 4 IPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSGI 60 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE---DGSLFP 415 RE+++ITSKLWNT HR ++V A ++TL +L + YLDLYL+H+P A++ GSL P Sbjct: 61 -KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNP 119 Query: 416 TDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQHATVKPVVNQ 589 D+ G F D V +DTWKAME LV++GLVK IGVSN+ QLERL A P NQ Sbjct: 120 LDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQ 179 Query: 590 VECHPYLNQKRLKEF 634 VE + Y+ Q L+E+ Sbjct: 180 VEFNLYMQQGPLREY 194 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 171 bits (416), Expect = 1e-41 Identities = 86/198 (43%), Positives = 126/198 (63%), Gaps = 6/198 (3%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T NG IP G GTWK + T AV AI GYRHIDCA+ Y NE +A+ + IK+ Sbjct: 13 TLANGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKK 68 Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY-KEDGSLFP 415 V R L++TSKLWN+FH P+ V AL +L +L YLDLYL+HWP A+ GS+ P Sbjct: 69 AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVP 128 Query: 416 TDQS---GKIQFSDV--DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580 + +S ++ D+ D++ T++ ME +VK+G V++IGVSNFN ++ ++ A++KPV Sbjct: 129 SIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPV 188 Query: 581 VNQVECHPYLNQKRLKEF 634 VNQVE + ++ + L+ + Sbjct: 189 VNQVEVNLGVHNEELRNY 206 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 170 bits (413), Expect = 3e-41 Identities = 86/194 (44%), Positives = 126/194 (64%), Gaps = 3/194 (1%) Frame = +2 Query: 62 FNNGET---IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 FN ET IP FGLGTW + G V AV+ A+ GYRHID A ++ NE EVG+ I Sbjct: 51 FNKNETVRDIPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGI---- 106 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 K V+R+++++T KLWNT HRP+LVR A++ ++ NL V+YLDLYLIH+P A+ Sbjct: 107 KASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAW------- 159 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 ++ + ++ +DTWKAME LV+ GL ++IG SNF K + ++L+ A+++P ++ Sbjct: 160 -VPETRDVD-NNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEF 217 Query: 593 ECHPYLNQKRLKEF 634 E HPYL Q+ +F Sbjct: 218 ETHPYLQQQSFVDF 231 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 169 bits (411), Expect = 5e-41 Identities = 94/212 (44%), Positives = 125/212 (58%), Gaps = 22/212 (10%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 ++G +P GLGTW SKP EV AV+ A+ +GYRHID A Y NE EVG K+ Sbjct: 10 SSGYDMPAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNG----WKKSG 65 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYL------------------ 370 V R+ +FITSKLWNT H PD V A+ +TL +L YLDLYL Sbjct: 66 VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLTN 125 Query: 371 --IHWPQAYKE-DGSLFPTDQ-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSK 538 IHWP A++ + +L P D S + + +++ DTW A+E LV G V+SIGVSNF + Sbjct: 126 NKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIE 185 Query: 539 QLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 ++E LL+ A + P VNQ+E HPYL Q L ++ Sbjct: 186 KIEELLKTARIPPAVNQIEAHPYLQQPALHKY 217 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 169 bits (410), Expect = 6e-41 Identities = 81/186 (43%), Positives = 115/186 (61%), Gaps = 1/186 (0%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 IP G GT + P A +DA+ G+RH DCA Y NE+EVGEA+ + G + RE+ Sbjct: 20 IPALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREE 79 Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439 +F+T+KLWNT HRP+ V A + +LD L + YLDLYLIH P A++ P DQ+G + Sbjct: 80 IFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVI 139 Query: 440 FSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616 + + V +TW A+E LV G ++IG+S+ + +L + + A +KP V QVE HPYL + Sbjct: 140 YDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPE 199 Query: 617 KRLKEF 634 L EF Sbjct: 200 TELLEF 205 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 169 bits (410), Expect = 6e-41 Identities = 92/205 (44%), Positives = 129/205 (62%), Gaps = 5/205 (2%) Frame = +2 Query: 35 MAPKIPVVTFNNG-ETIPVFGLGTWKSKPGE---VTQAVKDAIDIGYRHIDCAYVYGNEK 202 MA IP V ++G +PV GLGT P + V +AV +A+ +GYRH D A +Y +E+ Sbjct: 1 MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQ 60 Query: 203 EVGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 379 +G+AI + EG++ +R++LFITSKLW + + V ALQ+TL NL ++Y+D+YLIHW Sbjct: 61 PLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHW 120 Query: 380 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 559 P + K +P K F +DY W+AME K GL K+IGVSNF+ K+L +L Sbjct: 121 PVSSKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLA 177 Query: 560 HATVKPVVNQVECHPYLNQKRLKEF 634 +A V P VNQVE +P QK+L EF Sbjct: 178 NAKVPPAVNQVEVNPCWQQKQLTEF 202 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 169 bits (410), Expect = 6e-41 Identities = 86/199 (43%), Positives = 123/199 (61%), Gaps = 7/199 (3%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 T N G IP G GT+ ++ GE AV A+D+GYRH+DCA+ Y NE EVG+AI + Sbjct: 16 TLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFL 75 Query: 233 -KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS- 406 + VTR+DLFI +K+WN H P+ V+ + + + +NL V Y+DL+L+HWP A +++ Sbjct: 76 ARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADR 135 Query: 407 LFPTDQSGKIQFSDV---DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577 GK + + TW+AME LV G+VK+IGVSN+ L++LL+ A +KP Sbjct: 136 TVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKP 195 Query: 578 VVNQVECHPYLNQKRLKEF 634 VNQ+E HP+L L EF Sbjct: 196 AVNQIEIHPFLPNTELVEF 214 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 168 bits (409), Expect = 8e-41 Identities = 89/201 (44%), Positives = 124/201 (61%), Gaps = 4/201 (1%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGTW-KSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 KIP V N+G +PV G+GT +S+P + DAI +GYRH D A VYG E+ +G Sbjct: 5 KIPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGM 64 Query: 215 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391 A++ I++G++ +R+++FITSK WNT DL+ AL+ TL L ++Y+DLYLIHWP Sbjct: 65 AVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRL 124 Query: 392 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571 + D L K D TWKAME + GL KSIG+ N+ +K+L +LL+ AT+ Sbjct: 125 RHD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATI 182 Query: 572 KPVVNQVECHPYLNQKRLKEF 634 P VNQVE +P Q L+EF Sbjct: 183 PPAVNQVEMNPSWQQGNLREF 203 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 168 bits (409), Expect = 8e-41 Identities = 92/196 (46%), Positives = 119/196 (60%), Gaps = 4/196 (2%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIK 235 T NNG+TIP GLGTWKS EV AV+ A+ + GYRHID A+ Y NE VG I ++ Sbjct: 35 TLNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRAME 94 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 409 +GV RED+F+T+K+W T+H D V L +L+ L + Y+D+ LIHWP +G+ + Sbjct: 95 KGV-KREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLNPNGNDPV 151 Query: 410 FPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 +P G + TWK ME ++K G KSIGVSNF+ LE LL+ A V P VN Sbjct: 152 YPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEVVPAVN 211 Query: 587 QVECHPYLNQKRLKEF 634 QVE HP L Q L EF Sbjct: 212 QVELHPLLPQLELMEF 227 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 167 bits (406), Expect = 2e-40 Identities = 88/177 (49%), Positives = 108/177 (61%) Frame = +2 Query: 104 WKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW 283 W SKPG+V AVK AID GYRHIDCA+VYGNE EVG + K VV RED+FITSKLW Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64 Query: 284 NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVD 463 N H PD V A TL NL + Y+DLYL+HWP AY Sbjct: 65 NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAY------------------------ 100 Query: 464 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 +AME LV G K+IG+SNF+ K ++R+++ AT++P QVE HP L Q++L EF Sbjct: 101 --QAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEF 155 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 167 bits (406), Expect = 2e-40 Identities = 96/184 (52%), Positives = 115/184 (62%), Gaps = 8/184 (4%) Frame = +2 Query: 107 KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK--- 277 KS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI+E V REDLFI SK Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101 Query: 278 ---LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD 448 LW TF LVR A ++TL +L + YLD+YLIHWPQ +K Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------------------ 143 Query: 449 VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKR 622 AME LV EGLVK++G+SNFN Q+E+LL + KPV NQVECHPYL Q++ Sbjct: 144 --------AMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK 195 Query: 623 LKEF 634 L ++ Sbjct: 196 LIQY 199 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 167 bits (406), Expect = 2e-40 Identities = 84/191 (43%), Positives = 120/191 (62%), Gaps = 6/191 (3%) Frame = +2 Query: 80 IPVFGLGTWKSK-PGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 253 IP G GT+ + P ++ A+ AI+ G RHID A+ Y N+ +GE + +G + R Sbjct: 3 IPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKR 62 Query: 254 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK----EDGSLFPTD 421 ED+FIT+KLW T HR DLV L E L L + Y+DL+LIH P A+K +DG++ P D Sbjct: 63 EDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKD 122 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 + GKIQ+ +D ++T+ AME K+GL + IGVSNF+ +QLER+ + +KP NQVEC+ Sbjct: 123 EKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVECN 182 Query: 602 PYLNQKRLKEF 634 Y K L + Sbjct: 183 IYRQFKPLLSY 193 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 167 bits (405), Expect = 3e-40 Identities = 93/206 (45%), Positives = 123/206 (59%), Gaps = 1/206 (0%) Frame = +2 Query: 11 AAAKIISKMAPKIPVVTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYV 187 A IS K P+ N+G IP LGT+ +V QAV AI GYRHID A + Sbjct: 12 ALVNAISGEPGKAPLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAAL 71 Query: 188 YGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 367 YGNE+EVG+ I I++G+V RE+LF+T+KLWN H V AL+E+L L + Y+DLY Sbjct: 72 YGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLY 131 Query: 368 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 547 LIH P+A E+G P D+D ++TW ME K GL KSIGVSNF++ L+ Sbjct: 132 LIHSPEATNENGD--PV---------DIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLD 180 Query: 548 RLLQHATVKPVVNQVECHPYLNQKRL 625 RL+ + P VNQ+E HP Q++L Sbjct: 181 RLIAGSNTVPAVNQIEVHPSKTQEKL 206 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 166 bits (403), Expect = 4e-40 Identities = 91/197 (46%), Positives = 116/197 (58%), Gaps = 1/197 (0%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 IP + NNG IP GLG ++ E T+ A+K A+ GYRHID A YGNE+ VGEAI Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEAI- 69 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 +E V R+ +F+TSKLWN+ D + A QETLD L + YLDLYLIHWP Sbjct: 70 ---RESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAP----- 121 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 Y+D+W+AME L K G +K+IGVSNFN Q+ +L H TVKPVV Sbjct: 122 ----------------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVV 165 Query: 584 NQVECHPYLNQKRLKEF 634 +Q+E HPY Q + + Sbjct: 166 DQIETHPYFQQNDMHAY 182 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 165 bits (402), Expect = 6e-40 Identities = 87/180 (48%), Positives = 112/180 (62%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NNG IP G GT+++ QAVK+AI+ GYRHID A VYGNE+ VG+ I K+ Sbjct: 14 NNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGI----KDSG 69 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + REDLF+TSKLWNT + + A QETLD L + YLDLYLIHWP K+ G D Sbjct: 70 IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG-----DD 124 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 + KI +TW+AME L EG +++IGVSNF + L++ A V P V+Q+E HP Sbjct: 125 AAKIN------AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHP 178 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 165 bits (402), Expect = 6e-40 Identities = 84/191 (43%), Positives = 118/191 (61%), Gaps = 1/191 (0%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N IP GLGTW+S +AVK A+ GYR IDCA++YGNE EVGEA+ G Sbjct: 15 NTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAFN-GS 73 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + RED+F+TSKL+ T + + + +++ +L NL V YLDLYL+HWP + P Sbjct: 74 LKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSN 133 Query: 425 SGKIQFSDVDYVD-TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 SG ++ + WKAME L++ GLV++IGVSNF +Q++ LL+ A + P VNQV+ H Sbjct: 134 SGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLH 193 Query: 602 PYLNQKRLKEF 634 P+ Q L +F Sbjct: 194 PFWRQDELVKF 204 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 165 bits (400), Expect = 1e-39 Identities = 87/193 (45%), Positives = 113/193 (58%), Gaps = 3/193 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N G +IP GLGTW++K GEV QAV A+ GYRHID A Y NE EVG IK+ Sbjct: 42 NTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLG----IKDSG 97 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--LFPT 418 V R ++F+TSK+W+++H D V L TL +L YLDLYLIHWP +G+ LFP Sbjct: 98 VPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPVRLAPNGTHPLFPV 155 Query: 419 DQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 G D D TW ME ++K+G K+IG+SN +E +++ V P VNQVE Sbjct: 156 KPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGKVTPAVNQVE 215 Query: 596 CHPYLNQKRLKEF 634 HPY Q L ++ Sbjct: 216 LHPYCPQHALLKY 228 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 164 bits (398), Expect = 2e-39 Identities = 87/204 (42%), Positives = 129/204 (63%), Gaps = 5/204 (2%) Frame = +2 Query: 38 APKIPVVTFNNG---ETIPVFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEK 202 A +IP + F N + +PV G+G+ + + +A+ +A+ GYRH D A YG+E+ Sbjct: 4 AIEIPTIVFPNSSAQQRMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQ 63 Query: 203 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382 +GEA+ I G+V+R+DLF+TSKLW T + P LV AL+++L L ++YLDLYLIHWP Sbjct: 64 ALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWP 123 Query: 383 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 + + FP + + F D W++ME K GL K+IGVSNF+ K+L+ LL Sbjct: 124 LSSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSV 180 Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634 AT++PVV+QVE + QK+L+EF Sbjct: 181 ATIRPVVDQVEMNLAWQQKKLREF 204 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 162 bits (394), Expect = 5e-39 Identities = 87/200 (43%), Positives = 120/200 (60%), Gaps = 1/200 (0%) Frame = +2 Query: 38 APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217 A + + ++G IP GLGT K E+ A+ A++ GYRHID A+ Y NE +G+ Sbjct: 20 AQAVEKLKLSSGHEIPAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKI 79 Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397 + +G RED+FITSKL + +RP V L+ +L +L + Y+D+YLIH P A KE Sbjct: 80 LKKWFDKGG-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKE 138 Query: 398 DGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 +L D+ G F DVD+ WKAME VKEG KSIG+SNFN Q+ + +A +K Sbjct: 139 GENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIK 198 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P QVE H YL QK+L++F Sbjct: 199 PSNLQVETHAYLQQKQLRKF 218 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 162 bits (394), Expect = 5e-39 Identities = 85/190 (44%), Positives = 117/190 (61%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 +NG TIP+ G GT+ +V A+K A+D GYRH+DCA++YGNE VGEA IK Sbjct: 7 SNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEA----IKASG 62 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + R DLFITSK+WN D A +TL +L + YLDLYLIHWP ++D L Sbjct: 63 IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWPN--EDDFEL----- 115 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 +DTW+ +E L ++ V++IGVSNF+ QL+++ + ATVKP++NQ+E HP Sbjct: 116 ----------TLDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHP 165 Query: 605 YLNQKRLKEF 634 Y Q L +F Sbjct: 166 YKVQADLGQF 175 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 162 bits (394), Expect = 5e-39 Identities = 78/193 (40%), Positives = 118/193 (61%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 +TF NG T+P G GTW++ EV +A+ +A++ GYRHID A VY NEK +G+ + + Sbjct: 7 ITFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 G VTR++LFI +KL R V L+ +LD+L ++Y+DLY +H P E F Sbjct: 67 AGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFL 126 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 + + + D+V WKAME + + GL ++IG+SNFN +Q++R+L + +KP Q+E Sbjct: 127 VEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIE 186 Query: 596 CHPYLNQKRLKEF 634 H YL Q L +F Sbjct: 187 NHIYLQQPELVKF 199 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 162 bits (394), Expect = 5e-39 Identities = 81/197 (41%), Positives = 117/197 (59%), Gaps = 5/197 (2%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P N+G +P+ G G WK + AI GYR D A YGNE E G+ + Sbjct: 4 PSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARA 63 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDG 403 I+EG+V REDLFI SKLWN+FH D V ++ L + + Y DL+++H+P A Y + Sbjct: 64 IQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVDPA 123 Query: 404 SLFP---TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 +P ++ K++FS+ +TW AME LV + L +SIGVSNF+++ L LL++A ++ Sbjct: 124 VRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYARIR 183 Query: 575 PVVNQVECHPYLNQKRL 625 P Q+E HPYL Q+RL Sbjct: 184 PATLQIEHHPYLTQERL 200 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 161 bits (392), Expect = 1e-38 Identities = 85/200 (42%), Positives = 117/200 (58%) Frame = +2 Query: 29 SKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 208 S A +P + N+G IP G G ++ +PG+ QAVK A+D+GYRHID A +YGNE EV Sbjct: 6 SVSAMTVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEV 65 Query: 209 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388 + I + V R+++++TSKL N FH PD R A+ ++++ L +DLYLIHWP Sbjct: 66 AQGIA----DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLIHWP-- 118 Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 PT G D+V TWK +E G ++SIGVSNF L+RL Q AT Sbjct: 119 -------LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEAT 164 Query: 569 VKPVVNQVECHPYLNQKRLK 628 V P VNQ+E HPY + ++ Sbjct: 165 VVPAVNQIEVHPYFGNEEVR 184 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 160 bits (388), Expect = 3e-38 Identities = 85/189 (44%), Positives = 119/189 (62%), Gaps = 2/189 (1%) Frame = +2 Query: 71 GETIPVFGLGTW-KSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 GETIP+ G+GT+ K E T AV AI IGYRH D A +YG+E+ +G A+ I G Sbjct: 11 GETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGT 70 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 V R+DLF+TSKLW++ H + AL +TL + + YLD YL+HWP K G P + Sbjct: 71 VQRDDLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLK-PGVSEPIPK 127 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 + + D+ +TW+ ME ++ GL +SIGVSNF+SK++ LL A+V P VNQVE HP Sbjct: 128 EDEFE-KDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHP 186 Query: 605 YLNQKRLKE 631 Q++L++ Sbjct: 187 LWRQRKLRK 195 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 160 bits (388), Expect = 3e-38 Identities = 86/206 (41%), Positives = 123/206 (59%), Gaps = 4/206 (1%) Frame = +2 Query: 29 SKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKE 205 S+++ T NNG IP GLGTW + + +A A+ GY+HID A YGNE + Sbjct: 3 SQLSINTKTYTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQ 62 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 VG AI + V+R+++F+T+KLWN H+ GAL E+L L ++Y+DLYLIHWP Sbjct: 63 VGRAIA----DSGVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWP- 115 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG-LVKSIGVSNFNSKQLERLL-- 556 D + + D D+VDTW+ ++ + KEG VK+IGVSNFN K+L++LL Sbjct: 116 --------LSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNS 167 Query: 557 QHATVKPVVNQVECHPYLNQKRLKEF 634 + V PV+NQ+E HP L Q L ++ Sbjct: 168 EGVNVVPVINQIEAHPLLTQPDLFDY 193 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 159 bits (386), Expect = 5e-38 Identities = 91/195 (46%), Positives = 119/195 (61%), Gaps = 1/195 (0%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 +VT +NG +P FGLG W+S GEVT+ AV A+ GYRHID A +Y NE+ VG + Sbjct: 8 MVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGL--- 64 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 + V RED+FIT+KLWNT + A +E+ L V Y+DLYLIHWP+ K+ S Sbjct: 65 -RASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG-KDILS- 121 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 + GK Y+D+W+A E L KE V++IGVSNF+ LE +L TV P+VNQ Sbjct: 122 ----KEGK------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQ 171 Query: 590 VECHPYLNQKRLKEF 634 VE HP NQ L+ F Sbjct: 172 VELHPLNNQADLRAF 186 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 159 bits (385), Expect = 7e-38 Identities = 97/228 (42%), Positives = 133/228 (58%), Gaps = 17/228 (7%) Frame = +2 Query: 2 SSQAAAKIISKMA-PKIPVVTF--NNGETIPVFGLGTWK--SKPGEVTQAVKDAIDIGYR 166 S + I+ M PK + F NNG IP GLGT K E QAVK AI GYR Sbjct: 4 SVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYR 63 Query: 167 HIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLN 346 HID A+ Y E VGEAI +++G + REDLFIT+K+W D V +L E+L L Sbjct: 64 HIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALG 121 Query: 347 VQYLDLYLIHWPQAYKE-------DGSL-FPTDQSGKIQF-SDVDYVDTWKAMEPLV--- 490 ++Y+DL L HWP +++ G + P D SGK + +D DY++T+K +E + Sbjct: 122 LEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDP 181 Query: 491 KEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 + V++IGVSNF+ + LERL++ VKP VNQVE HP+L Q L++F Sbjct: 182 NDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKF 229 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 157 bits (382), Expect = 2e-37 Identities = 79/192 (41%), Positives = 118/192 (61%), Gaps = 4/192 (2%) Frame = +2 Query: 71 GETIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 G +P G+GT S P A A+++G+RH D A +YG E +GEAI + G Sbjct: 14 GRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEAIAEATRRG 73 Query: 242 VV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 +V +RE++F+T+KLW T P LV +L+E+L NL ++Y+DLYL+HWP + K + P Sbjct: 74 LVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLPV 133 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 + + F D+ W+AME + GL K+IGVSNF +K L++LL AT+ P VNQVE Sbjct: 134 KREDAVPF---DFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVEM 190 Query: 599 HPYLNQKRLKEF 634 +P Q+ ++E+ Sbjct: 191 NPVWQQRTVREY 202 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 157 bits (381), Expect = 2e-37 Identities = 86/186 (46%), Positives = 113/186 (60%), Gaps = 2/186 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 NN IP G GTW++ G+ A+K AID GY+HID A +Y NEK VG I KE Sbjct: 8 NNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI----KEA 63 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 + R+DLF+TSK+WN + A T+++L + YLDLYLIHWP A + Sbjct: 64 NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ-------F 116 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 ++ K Q ++ DTW AME L K+G +K++GVSNF L LLQHAT+KP VNQ+E H Sbjct: 117 ENWK-QLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYH 171 Query: 602 P-YLNQ 616 P Y+ Q Sbjct: 172 PGYMQQ 177 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 157 bits (381), Expect = 2e-37 Identities = 79/197 (40%), Positives = 116/197 (58%), Gaps = 4/197 (2%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 VT ++G +PV GLG W+ + E+ + + +AI IGYRH DCA Y +E +VGEA+ K Sbjct: 4 VTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 G+V RE+LFIT+K+WN+ H V A + +L+ L + YLDLYL+H+P K + Sbjct: 64 TGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKT 121 Query: 416 TDQSGKIQFSDVDYV----DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 G+ + D+D TW+ ME V GLV+SIG+SN+ L ++ +KP V Sbjct: 122 ASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAV 181 Query: 584 NQVECHPYLNQKRLKEF 634 +Q E HPY + L +F Sbjct: 182 SQFETHPYFQRDSLVKF 198 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 157 bits (380), Expect = 3e-37 Identities = 81/180 (45%), Positives = 114/180 (63%), Gaps = 1/180 (0%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 +G +P GLGTW++ + +V+ AI + GYRH+D A YG EKEVG+ + + ++ G+ Sbjct: 20 SGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAGI 78 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 R+DLF+TSK+W T P+ VR AL+ TL +L + Y+DLY IHWP K DG+ P + Sbjct: 79 -DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPPEA 136 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 ++F D WK ME LVK+GLVK IGV N+ +L RLL+ A + P V Q+E HP Sbjct: 137 GEVLEF---DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHP 193 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 156 bits (378), Expect = 5e-37 Identities = 81/192 (42%), Positives = 114/192 (59%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P++ +G +P GLG+W S ++ + + A+DIGYR ID A +Y NEK VG A Sbjct: 5 PIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA---- 60 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 ++E + RED+F+T+KLWN H R AL E+L+ L + Y+DLYLIHWP Sbjct: 61 LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWPAP------- 111 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 P DQ YV W+ + L KEGL++SIGVSNF + ++RL+ V PV+NQ Sbjct: 112 -PQDQ----------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQ 160 Query: 590 VECHPYLNQKRL 625 +E HP L Q++L Sbjct: 161 IELHPLLQQRQL 172 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 155 bits (375), Expect = 1e-36 Identities = 89/194 (45%), Positives = 118/194 (60%), Gaps = 1/194 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 V +NG +P FGLG +K + G E T++VK AI GYR ID A +Y NE+ VG I Sbjct: 9 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI---- 64 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 KE V RE+LFITSK+WN + A +++L+ L + YLDLYLIHWP Sbjct: 65 KESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------- 114 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 GK + Y DTW+A+E L K+G +++IGVSNF LE LL+ A +KP+VNQV Sbjct: 115 -----GKDK-----YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQV 164 Query: 593 ECHPYLNQKRLKEF 634 E HP L QK L+++ Sbjct: 165 EFHPRLTQKELRDY 178 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 154 bits (374), Expect = 1e-36 Identities = 80/199 (40%), Positives = 116/199 (58%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 M+ K+P+ T +NG +P GLGTW+ E +++A+ GYRHID A +Y NE ++G+ Sbjct: 1 MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGD 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 A+ EG++ RED+FIT+K + PD+V AL+ +L L + Y+DLYL H P + K Sbjct: 61 ALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTK 120 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 +DGS SDV D W+ E + GL K+IGVSNFN Q+ R++ V Sbjct: 121 DDGSF----------RSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVP 170 Query: 575 PVVNQVECHPYLNQKRLKE 631 +Q+E H YL QK +E Sbjct: 171 IHASQLELHLYLPQKAHRE 189 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 154 bits (374), Expect = 1e-36 Identities = 80/193 (41%), Positives = 117/193 (60%), Gaps = 1/193 (0%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T N G IP G+GT++ P + V + G R ID A VYG E++VG I K+ Sbjct: 39 TLNTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGI----KK 93 Query: 239 GVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 V RE++F+ +KLW N FH PD V A+ ++L +L Y+DL L+H+P +K FP Sbjct: 94 SGVPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFP 152 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 D G++ + +VDTW+A+E +VK G V++IGVSNF+ ++E LL+ + P V+Q+E Sbjct: 153 RDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQME 212 Query: 596 CHPYLNQKRLKEF 634 HPYL QK E+ Sbjct: 213 VHPYLQQKGFNEW 225 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 154 bits (373), Expect = 2e-36 Identities = 83/203 (40%), Positives = 120/203 (59%), Gaps = 1/203 (0%) Frame = +2 Query: 29 SKMAPKIPVVTFNNGETIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKE 205 +K P + NNG ++P+ GLG WK+K G E +AV +A++ GYRHID A +Y NE + Sbjct: 3 NKENPLKQTIMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVD 62 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 VG+AI +E + R+++FIT+KLWN D R AL+ +LD L + ++DLYLIH+P Sbjct: 63 VGQAI----RESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPV 118 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 K +D+WK +E L + L K+IGVSN+ L LL+++ Sbjct: 119 TSKR--------------------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNS 158 Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634 + P VNQVE HP+LNQ L E+ Sbjct: 159 QITPAVNQVEFHPFLNQIHLLEY 181 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 153 bits (372), Expect = 3e-36 Identities = 80/202 (39%), Positives = 115/202 (56%), Gaps = 2/202 (0%) Frame = +2 Query: 35 MAPKIPV-VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211 M PK + ++ + +P GLGT+ + +A++ AID+GYR D A YGNE VG Sbjct: 1 MIPKTCINLSDQHSIALPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVG 60 Query: 212 EAITSKIKE-GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388 EAI KI+E +TR+D FI SKL ++HR DLV + TLD L + Y+DLYL+H P A Sbjct: 61 EAIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVA 120 Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 + + + + W +E +EGL +SIGVSNFN Q+ LL A+ Sbjct: 121 LQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDAS 180 Query: 569 VKPVVNQVECHPYLNQKRLKEF 634 + P VNQ+EC NQ+ +++F Sbjct: 181 IVPAVNQIECSIGFNQRPMRKF 202 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 153 bits (371), Expect = 3e-36 Identities = 80/202 (39%), Positives = 115/202 (56%), Gaps = 5/202 (2%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGTWKSK---PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 KIP T +G +P G+GT+ S PGEV +V A ++GYRH DCA VY NE+E+G Sbjct: 15 KIPQRTLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGA 74 Query: 215 AITSKIKEGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP-QA 388 + + REDL+ITSKLWN H V A +++L +L + YLDLYLIHWP Sbjct: 75 TFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPN 134 Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 + G + + +++ TW+ +E L GLV+ IG SN +L+ LL+ A Sbjct: 135 FHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDAR 194 Query: 569 VKPVVNQVECHPYLNQKRLKEF 634 V+P VN++E HP+ Q L ++ Sbjct: 195 VRPAVNEMELHPHFQQPALFDY 216 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 153 bits (371), Expect = 3e-36 Identities = 81/200 (40%), Positives = 115/200 (57%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MA K VT +NG +P G+GTW++K G +K A++ GYRH+D A+ Y NEK VG+ Sbjct: 1 MAVKCTHVTLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQ 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 I+ E V R D+F+T+KLWN H + A +++ L V+Y+DLYLIHWP + Sbjct: 61 GIS----ECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWPGPNR 116 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 Y++TW+A E L + V++IGVSNF L+ LL + TV Sbjct: 117 -------------------SYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVP 157 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P+VNQVE HP+ QK L+ + Sbjct: 158 PMVNQVEMHPHFQQKALRAY 177 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 153 bits (371), Expect = 3e-36 Identities = 84/195 (43%), Positives = 108/195 (55%), Gaps = 12/195 (6%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 + + TIP G GT++ E T AV A+ GYRH+DCA YGNE VGEA+ ++ Sbjct: 22 IAMRDSHTIPQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALR 81 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA------YKE 397 REDLF+TSKLW T PD V A + TL L + YLDLYLIHWP + Sbjct: 82 TRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTS 141 Query: 398 DGSLFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH-ATV 571 D +P + G + V +DTW AM LV GLVKSIG++N + + L++ A Sbjct: 142 DEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEA 201 Query: 572 K----PVVNQVECHP 604 K PV+NQVE HP Sbjct: 202 KLAHLPVLNQVEHHP 216 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 153 bits (371), Expect = 3e-36 Identities = 87/200 (43%), Positives = 123/200 (61%), Gaps = 10/200 (5%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N G+TIP GLGTW+SK E +AV +A+ GYRHID A VYGNE EVG+A I++ Sbjct: 14 NTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA----IQDSG 69 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK----EDGSLF 412 V R ++F+T+KLW T R + AL ++L L + Y+ LYL+HWP + +DG+LF Sbjct: 70 VPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLRTENIKDGNLF 127 Query: 413 ----PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK-- 574 D S + + +++ TW+ M+ L++ G K+IGVSNF+ L+ LL T K Sbjct: 128 QFAEKPDGSKDVDL-EWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLLAAPTTKVT 186 Query: 575 PVVNQVECHPYLNQKRLKEF 634 P VNQVE HP L Q+ L ++ Sbjct: 187 PAVNQVEFHPLLPQEELIQY 206 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 153 bits (371), Expect = 3e-36 Identities = 80/190 (42%), Positives = 109/190 (57%), Gaps = 6/190 (3%) Frame = +2 Query: 74 ETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 253 + +P+ G G WK + + + AI IGYR D A YGNE EVG I IKEG+V R Sbjct: 13 DKMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKR 72 Query: 254 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW--PQAYKEDGSLFPTD-- 421 E+LFI +KLWNTFH VR A L + ++Y DLYLIH+ P Y + +P + Sbjct: 73 EELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWY 132 Query: 422 --QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 + K+ F + W ME LV+ L ++IGV+NFN + + LL +A +KP V Q+E Sbjct: 133 VPHADKLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIE 192 Query: 596 CHPYLNQKRL 625 HP L Q+RL Sbjct: 193 IHPLLPQERL 202 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 153 bits (371), Expect = 3e-36 Identities = 82/196 (41%), Positives = 120/196 (61%), Gaps = 6/196 (3%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N+G +IP GLGT + G V + V AI GYRHID A++YG+E +VG+ I I E + Sbjct: 10 NDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEEL 67 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG----SLF 412 V RE+LF+T+K+W TF+ + V +L +L +L++ Y+DL L+HWP + D +++ Sbjct: 68 VKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAIY 125 Query: 413 PTDQSGKIQFSDV--DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 + G +++SD D++ T+K +E G KSIGVSN + L+RLL P VN Sbjct: 126 LVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVPAVN 185 Query: 587 QVECHPYLNQKRLKEF 634 Q E HPYL QK+ EF Sbjct: 186 QFEIHPYLPQKKEIEF 201 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 152 bits (369), Expect = 6e-36 Identities = 86/205 (41%), Positives = 122/205 (59%), Gaps = 11/205 (5%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 +++ N G IP GLGTW+SK + +AV A+ GYRHID A +Y NE +VG+A I Sbjct: 11 ILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQA----I 66 Query: 233 KEGVVTREDLFITSKLWNT-FHRPDLVRGALQETLDNLNVQYLDLYLIHWP----QAY-- 391 K+ V RE++F+T+KLW T H P++ AL ++L L + Y+DLYL+HWP AY Sbjct: 67 KDSGVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPAYIK 123 Query: 392 KEDGSLFPTDQSGK--IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--Q 559 ED PT + G + ++ +++ TW+ M+ L K G K++GVSNF+ L+ LL Q Sbjct: 124 NEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQ 183 Query: 560 HATVKPVVNQVECHPYLNQKRLKEF 634 + P NQVE HP L Q L F Sbjct: 184 GNKLTPAANQVEIHPLLPQDELINF 208 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 152 bits (368), Expect = 8e-36 Identities = 80/193 (41%), Positives = 114/193 (59%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 VT NNG +P G G +K EV +AV++A+ +GYR ID A +Y NE VG A +K Sbjct: 4 VTLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRA----LK 59 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 + + RED+F+T+K+WN + A + +L L V Y+DLYLIHWP D L Sbjct: 60 DSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---PDEDL-- 114 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 Y+DTW+A+E L ++G K+IGVSNF+ L R+L+ TV P VNQ+E Sbjct: 115 -------------YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIE 161 Query: 596 CHPYLNQKRLKEF 634 HP+L+Q+ ++ F Sbjct: 162 LHPFLSQEAIRAF 174 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 151 bits (366), Expect = 1e-35 Identities = 75/191 (39%), Positives = 119/191 (62%), Gaps = 2/191 (1%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 NGE +P+ G GTW+++ E+ A+ A++ GYRHID A Y NEK +G+ + + + Sbjct: 10 NGELMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKKL 69 Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTDQ 424 R D+FI +KL +R + V ++ +L NL ++YLDLYLIH P +++ G L P D+ Sbjct: 70 KRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFDE 129 Query: 425 SGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 +G I+ + ++V+ W ME VK G K+IG+SNFN Q++R+L++ +K + Q+E H Sbjct: 130 NGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIELH 189 Query: 602 PYLNQKRLKEF 634 Y QK L +F Sbjct: 190 VYFQQKELVKF 200 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 151 bits (366), Expect = 1e-35 Identities = 79/194 (40%), Positives = 113/194 (58%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 V NNG +P GLG +K ++ + V+ A+D GYR D AY YGNEK +G A+ Sbjct: 5 VQILNNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSAL---- 60 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 K V R++LFITSKLWN + D ++LDNL + YLDL+LIHWP Sbjct: 61 KHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCE-------- 112 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 +D Y++++KA+E L +EG +K+IGV NF LE+L++ + P VNQ+ Sbjct: 113 ----------NDQLYIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQI 162 Query: 593 ECHPYLNQKRLKEF 634 E HPY NQ+ +++F Sbjct: 163 ELHPYFNQQDVQDF 176 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 151 bits (365), Expect = 2e-35 Identities = 82/199 (41%), Positives = 111/199 (55%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 M+ K+P + NNG +P G G W+ + AV A++ GYR ID A +YGNE+ G Sbjct: 1 MSSKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGR 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 AI + + REDLF+T+KLWN+ D A ++ L ++YLDLYLIHWP K Sbjct: 61 AIAA----SGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAK 116 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 E YVDT+KA E L+ +G V++IGVSNF + LERL +V Sbjct: 117 E------------------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVI 158 Query: 575 PVVNQVECHPYLNQKRLKE 631 P VNQ+E HP+L Q +E Sbjct: 159 PAVNQIELHPHLQQHAARE 177 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 150 bits (363), Expect = 3e-35 Identities = 82/193 (42%), Positives = 109/193 (56%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 VT NNG IP GLG ++ E + V++ I GYR ID A +YGNE G I + + Sbjct: 9 VTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLA 68 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 + REDLF+TSK+WN D A ++L+ L + YLDLYLIHWP Sbjct: 69 ATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP----------- 117 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 + Y ++W+A+E L EG VK+IGVSNF LE LL +A V PV+NQVE Sbjct: 118 ---------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVE 168 Query: 596 CHPYLNQKRLKEF 634 HP L+QK +++F Sbjct: 169 LHPKLDQKEVRDF 181 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 149 bits (361), Expect = 5e-35 Identities = 77/183 (42%), Positives = 115/183 (62%), Gaps = 1/183 (0%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 T NNG IP+ G GTW++ GEV + +V A++ GYRHID A YGNE VG AI K Sbjct: 11 TLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ---K 67 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 G+ R +LFIT+KLWN+ H + + A+ ++L +L + YLD+YLIHW P Sbjct: 68 SGI-NRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHW-----------P 115 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 S + +++++ ++W+AME V+ G +++IGVSNF L+ L++ A +KPVVNQ+ Sbjct: 116 NPSSMRDHWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIF 174 Query: 596 CHP 604 +P Sbjct: 175 LNP 177 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 149 bits (361), Expect = 5e-35 Identities = 82/204 (40%), Positives = 118/204 (57%), Gaps = 7/204 (3%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205 KIP + N+G IPV GLGT K VT ++ A++ GYRH D A YGNE Sbjct: 10 KIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAI 69 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 +G+ + I EG V RE+LFIT+KL +R V LQ++LDNL + Y+DLYL+H+P Sbjct: 70 IGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPC 129 Query: 386 AYKE-DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 + D D+ +D+ + W+AME + G K+IG+SNFN+ Q++R+++ Sbjct: 130 GILDTDRERLSADEVTVDPTTDIHAI--WRAMEAQLAAGKTKNIGLSNFNADQVQRIIKG 187 Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634 V+P V QVE H Y+ Q L+ F Sbjct: 188 CQVRPAVLQVEVHVYMQQGALRAF 211 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 149 bits (361), Expect = 5e-35 Identities = 87/198 (43%), Positives = 112/198 (56%), Gaps = 5/198 (2%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 V N+G +PV G GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 403 KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A K+ G Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGK 130 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 L P D SG+I V+ DTW+ L K GL KP Sbjct: 131 ELLPKDASGEIILETVELCDTWELELILNKPGL---------------------RYKPTC 169 Query: 584 NQ-VECHPYLNQKRLKEF 634 NQ VECHPYLNQ +L EF Sbjct: 170 NQVVECHPYLNQSKLLEF 187 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 149 bits (360), Expect = 7e-35 Identities = 76/195 (38%), Positives = 118/195 (60%), Gaps = 3/195 (1%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 + ++G +P+ GLGTW+ P + AV A++ GYRHID A+ YGNE+ +G+ + Sbjct: 28 IKLSSGHDMPMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFD 87 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 +G REDLFIT+KL R + V L+ +L+ L ++Y+++YLIH P A+ +D + Sbjct: 88 KGG-KREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYE 146 Query: 416 T--DQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 + G + +D D+V W+AME VK G V+SIG+SNFN QL + +HA +KP Sbjct: 147 PALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAEIKPSNL 206 Query: 587 QVECHPYLNQKRLKE 631 Q+E Y Q+ ++E Sbjct: 207 QIELQAYNQQRPMRE 221 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 148 bits (359), Expect = 1e-34 Identities = 78/190 (41%), Positives = 116/190 (61%), Gaps = 1/190 (0%) Frame = +2 Query: 68 NGETIPVFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NG +PVFGLGT+K E+ ++ A+D+GYRHID A +Y NEK++G+A+ KEG Sbjct: 12 NGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYKEGK 71 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 REDLF+ +KL++ ++ V ++++L NL Y+DLYL+H+ S PTDQ Sbjct: 72 YKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHY-------ASSPPTDQ 122 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 + + W E LV++GL+++IG+SNFN + L L + +KPVVNQ+E + Sbjct: 123 ---FELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNV 179 Query: 605 YLNQKRLKEF 634 Y Q RL EF Sbjct: 180 YCQQPRLLEF 189 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 147 bits (357), Expect = 2e-34 Identities = 84/203 (41%), Positives = 126/203 (62%), Gaps = 3/203 (1%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVG 211 + P I + NNG +P+ G+GT+K + EV + V D + +G+R ID A VY NE+++G Sbjct: 19 LTPTIRDLRLNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIG 78 Query: 212 EAITSKIKEGVVTREDLFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388 A+ + + + RED+FITSKL + + PD +R +++++L L+ YLDLYLIHWP A Sbjct: 79 LALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGA 138 Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 + L + + K++ V TW + L ++GL++SIGVSN+ LE LL+H + Sbjct: 139 SR---ILENSPDNPKLR------VTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCS 189 Query: 569 -VKPVVNQVECHPYLNQKRLKEF 634 VKP VNQVECHP+ Q L EF Sbjct: 190 GVKPDVNQVECHPHFRQDELIEF 212 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 147 bits (357), Expect = 2e-34 Identities = 85/204 (41%), Positives = 120/204 (58%), Gaps = 6/204 (2%) Frame = +2 Query: 38 APKIPVVTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 A +P VT N+G +PV G GT S P ++ + A+ +GYRH+D A VYG E VG Sbjct: 17 ATAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGA 76 Query: 215 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391 A+ ++ G V +R +LF+T+KL P V AL+E+L L + Y+DL+LIHWP A Sbjct: 77 AVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAI 136 Query: 392 -KED--GSLFPTDQS-GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 559 K+D G L D S G + F D W+ ME + GL +SIGVSNF++ ++ RLL Sbjct: 137 GKKDAAGELTWDDLSRGLVPF---DMEGVWRGMEECHRLGLARSIGVSNFSAAKMSRLLA 193 Query: 560 HATVKPVVNQVECHPYLNQKRLKE 631 A V P VNQVE + Q++++E Sbjct: 194 LAAVPPAVNQVEMNVGWRQEKVRE 217 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 147 bits (357), Expect = 2e-34 Identities = 80/204 (39%), Positives = 116/204 (56%), Gaps = 8/204 (3%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWK-----SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211 +P ++G+ +P G+GT + P V V AI+ GYRH D A VY E +G Sbjct: 1 MPEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60 Query: 212 EAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388 +A+ ++ G+V +R++L+ITSKLW P V +L+ L + ++YLDLYLIH+P + Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120 Query: 389 YK--EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 + ED + + +D WK ME + GL K+IGVSNF+ K+LE LL Sbjct: 121 MRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSF 177 Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634 AT+ P NQVE HPY Q +L+EF Sbjct: 178 ATISPAANQVEVHPYCRQNKLREF 201 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 147 bits (356), Expect = 2e-34 Identities = 85/203 (41%), Positives = 124/203 (61%) Frame = +2 Query: 26 ISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205 +S+ IP+ NNG IPVFGL + EV + V+ + YR +DC+ ++ NEK Sbjct: 1 MSQKMRDIPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKR 57 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 G A+ I+ G + R+DLF+ SK T + +LV+ AL +TL L V YLDLYLI P Sbjct: 58 FGVALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPP 116 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 A K D + ++TW+AME L E L ++IG+SNFNSKQ+ER+L++ Sbjct: 117 ACK-----------------DHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENC 159 Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634 T++P VNQ++CHPYLNQ +L+++ Sbjct: 160 TIRPQVNQIQCHPYLNQAKLRKY 182 Score = 138 bits (333), Expect = 1e-31 Identities = 61/104 (58%), Positives = 81/104 (77%), Gaps = 1/104 (0%) Frame = +2 Query: 326 ETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGL 502 E+L NL + YLD+YL+HWP A KE SL P D ++G SDVD+VDTWKAME + ++ L Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330 Query: 503 VKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 KSIG+SNFNS Q++RLL+ A + PV+NQ+ECHPYLNQ +L++F Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKF 374 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 147 bits (355), Expect = 3e-34 Identities = 83/214 (38%), Positives = 130/214 (60%), Gaps = 11/214 (5%) Frame = +2 Query: 26 ISKMAPKIPVVTFNNGETIPVFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEK 202 ++++A + V +NG+TIP GLGT + P E+ + V A+ GYRHID A+ YG E+ Sbjct: 1 MTQLATDVDFV-LSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEE 59 Query: 203 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382 +G+A+ +EG+V REDLFIT+K+W +F R +L ++L +L + Y+DL+L HWP Sbjct: 60 YIGQALKQLFEEGIVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWP 117 Query: 383 QAYKEDGSLF---PTDQSGKIQFSD-----VDYVDTWKAMEPLV-KEGLVKSIGVSNFNS 535 D + P D+ GK+ + D + Y+D + ++E ++ VKSIGVSN++ Sbjct: 118 VVLHGDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSI 177 Query: 536 KQLERLLQHATV-KPVVNQVECHPYLNQKRLKEF 634 +L +LL KPVVNQ+E HP L Q+ L ++ Sbjct: 178 PKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKY 211 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 146 bits (354), Expect = 4e-34 Identities = 78/190 (41%), Positives = 112/190 (58%), Gaps = 1/190 (0%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NG IP G G +K GE + AV +AI IGYRH D A +YGNEK++G AI ++ Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + RE+ FITSK+WNT H + + A ++T LNV+YLD+YLIH+ +Y Sbjct: 68 IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 Y++TW AME L +G +K IGV+NF + LE L++H+ + P++NQ+E HP Sbjct: 117 ----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHP 166 Query: 605 YLNQKRLKEF 634 Q L ++ Sbjct: 167 EFPQNELHQY 176 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 146 bits (354), Expect = 4e-34 Identities = 80/181 (44%), Positives = 110/181 (60%), Gaps = 3/181 (1%) Frame = +2 Query: 83 PVFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256 P+ G GTW K P T+AV AI+IGYR IDCA VYGNE VG I +K + RE Sbjct: 40 PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99 Query: 257 DLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 433 D+++TSKLWN H + V L +TL +L ++YLDLYLIHWP + +G+ Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA--------- 150 Query: 434 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 613 ++D+V T+K+M L K V +IGVSNF+ QL+ ++ T+ P ++Q+E HPYL Sbjct: 151 ---KNLDHVQTYKSMISLPK-SRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQ 205 Query: 614 Q 616 Q Sbjct: 206 Q 206 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 145 bits (351), Expect = 9e-34 Identities = 79/194 (40%), Positives = 110/194 (56%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 V++F++G T+P GLG W++ P E + VK+A+ +GYR +D A +Y NE+ VG Sbjct: 13 VISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVG------- 65 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 +G+ ++F+T+KLWN D A +E+ L LDLYLIHWP Sbjct: 66 -KGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP-------- 116 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 + YV+TWKA+ L K G VKSIGVSNF S+ LER++ V PVVNQ+ Sbjct: 117 ----------AQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQI 166 Query: 593 ECHPYLNQKRLKEF 634 E HP Q+ L+EF Sbjct: 167 ELHPDFQQRALREF 180 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 145 bits (351), Expect = 9e-34 Identities = 83/199 (41%), Positives = 116/199 (58%), Gaps = 7/199 (3%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKD----AIDIGYRHIDCAYVYGNEKEVGEA 217 P + N G +P LG W E K+ A+ GYRHID A +Y EK VG A Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVGNA 64 Query: 218 ITSKIKEGVVTREDLFITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ-AY 391 I +E + RE+LFIT+KL WN R V + Q++L+NL +Y+DLYL+H+PQ + Sbjct: 65 I----RESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFPQRVF 117 Query: 392 KEDGSLFPTDQSGKIQFSDVDYV-DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 ++ + FP + G I+ + + D W +E L+ G VK+IGVSN++ K LE LL+ A Sbjct: 118 YDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELLKTAK 177 Query: 569 VKPVVNQVECHPYLNQKRL 625 V P VNQVE HP+L Q +L Sbjct: 178 VVPAVNQVELHPFLAQSKL 196 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 145 bits (351), Expect = 9e-34 Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 14/214 (6%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPG-----EVTQAVKDAIDIGYRHIDCAYVYGNE 199 MA IP T N G +P G+G W+ +PG E+ A+ AI +GYRH+D A Y NE Sbjct: 1 MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNE 60 Query: 200 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQE---TLDNLNVQYLDLYL 370 EVG+A+ ++ V R ++F+T+KL RP V +QE +L+ L + Y+DL+L Sbjct: 61 AEVGQAV----RQSGVARSEIFVTTKL-----RPGGVHDVVQELENSLNELGIDYIDLWL 111 Query: 371 IHWPQAYKEDGSLFPTDQSGKIQFSD---VDYVDTWKAMEPLV---KEGLVKSIGVSNFN 532 +HWPQ + +D F T +S ++ + +TW ME + +G VK+IGVSNF+ Sbjct: 112 LHWPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFS 171 Query: 533 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 K LE L + + V P VNQ+E HPYL + L ++ Sbjct: 172 IKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKY 205 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 144 bits (348), Expect = 2e-33 Identities = 79/197 (40%), Positives = 114/197 (57%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 ++P VT NNG +P+ G G ++ P + + V +AI +GYR ID A Y NE+ VG AI Sbjct: 2 QVPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIK 61 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 I EG+V RE+LF+T+KLW + + + A +++L L ++Y+DLYLIH P Sbjct: 62 RAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP------- 114 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 F DV WKAME + K+GLV++IGVSNF +L L+ H + P V Sbjct: 115 ------------FGDVHC--AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAV 160 Query: 584 NQVECHPYLNQKRLKEF 634 NQ+E HP+ ++ EF Sbjct: 161 NQIEIHPFYQRQEEIEF 177 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 144 bits (348), Expect = 2e-33 Identities = 76/188 (40%), Positives = 101/188 (53%), Gaps = 4/188 (2%) Frame = +2 Query: 83 PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 256 P G GT+ + E A++ A+ +GYRH DCAY YGNE+ +GE + V RE Sbjct: 6 PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSG 430 DL+I SKLW FH P+ V + ETL +L ++YLD++L+HWP A K D +D G Sbjct: 63 DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610 TW+AME V + + IGVSN + L LL + +KP NQ E PY Sbjct: 123 GTLLGTTPIRKTWEAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYF 182 Query: 611 NQKRLKEF 634 RL EF Sbjct: 183 PNDRLIEF 190 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 142 bits (345), Expect = 5e-33 Identities = 77/193 (39%), Positives = 116/193 (60%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 +P V +G +IP FGLGT++ P E + V+ AI++GYRHID A +Y NE+EVG AI S Sbjct: 9 VPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRAIAS 68 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 + RE+ F+T+KLWN+ +P R A + +LD L++ Y+DLYLIHWP Sbjct: 69 ----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWPCP------ 116 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 P++ Y++ W+ + L + G KS+GVSNF S+ ++++ + P VN Sbjct: 117 --PSEL----------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVN 164 Query: 587 QVECHPYLNQKRL 625 Q+E HP+L Q+ L Sbjct: 165 QIELHPWLQQREL 177 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 142 bits (344), Expect = 6e-33 Identities = 77/193 (39%), Positives = 108/193 (55%), Gaps = 1/193 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 + NNG+ IP LG +K+ G A K A D GYRHID A Y NE+ VG A+ Sbjct: 19 IKLNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWT 78 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 KE V R ++FITSKLW+ H D A++++L LNV Y+D+YL+H P + L Sbjct: 79 KENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKRL- 135 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 + WKA+E V G +K+IGVSNF+ ++L+ LL + +KP VNQ+ Sbjct: 136 ----------------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQI 179 Query: 593 ECHPYLNQKRLKE 631 E HP+ + L+E Sbjct: 180 ESHPFFAHEELRE 192 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 142 bits (343), Expect = 8e-33 Identities = 78/183 (42%), Positives = 105/183 (57%), Gaps = 1/183 (0%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 T NNG IP+ G GTW++ G+V +V A+ GYRHID A YGNE+ VG+AI Sbjct: 12 TLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA---- 67 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 + V REDLF+T+KLWN H D + AL +L L + Y+DLYLIHWP Sbjct: 68 DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNP--------- 118 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 + + + ++ DTW+AME ++IGVSNF K L+ LL+ A V P VNQ+ Sbjct: 119 --AAMRDNWEQLN-ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIF 175 Query: 596 CHP 604 +P Sbjct: 176 LNP 178 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 141 bits (341), Expect = 1e-32 Identities = 75/196 (38%), Positives = 109/196 (55%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 +P + N+G +IP G G +K P + +AV++A+++GYRHID A +YGNE+ VG AI + Sbjct: 3 VPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAA 62 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 + R+DLFIT+KLWN H D A+ E+L L + +DLYL+HWP + Sbjct: 63 ----SGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAAD--- 115 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 +YV W+ M L GL +SIGVSN LER++ V P VN Sbjct: 116 ---------------NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVN 160 Query: 587 QVECHPYLNQKRLKEF 634 Q+E HP Q+ + ++ Sbjct: 161 QIELHPAYQQREITDW 176 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 140 bits (340), Expect = 2e-32 Identities = 79/196 (40%), Positives = 110/196 (56%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP + ++G +IP GLG W+ ++ A + GYR ID A +YGNE+ VG AI Sbjct: 59 IPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRAI-- 116 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 + + R++L+IT+K+WN+ D A++E+L L ++Y+DLYLIHWP Sbjct: 117 --RASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPVP------ 168 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 KI YVDTWKA+ + +GL +SIGVSNF L+RL + PVVN Sbjct: 169 --------KID----RYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVN 216 Query: 587 QVECHPYLNQKRLKEF 634 QVE HP L Q L+ F Sbjct: 217 QVELHPRLQQHELRAF 232 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 140 bits (340), Expect = 2e-32 Identities = 75/190 (39%), Positives = 115/190 (60%), Gaps = 4/190 (2%) Frame = +2 Query: 74 ETIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 +T+P G+GT + + T A+ AI++GYRH D A +Y E VGEA+ ++ G+ Sbjct: 14 QTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGL 73 Query: 245 V-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 + +R D+F+TSK+W + V A +ETL NL + Y+DL L+HWP + FP Sbjct: 74 IASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFP 133 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 + + D++ V W+ ME + GL ++IGVSNF++K+LE+LL A V+P VNQVE + Sbjct: 134 KEVILPSFDMEGV--WRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVN 191 Query: 602 PYLNQKRLKE 631 P Q+ L+E Sbjct: 192 PMWQQRTLRE 201 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 140 bits (339), Expect = 3e-32 Identities = 71/190 (37%), Positives = 111/190 (58%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP +T N+G +P G GT+K + + +AV+ AI++GYRHID A +Y NE+EVG A+ Sbjct: 11 IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 I G V R++LFIT+K+WN H L + + QE+L L + Y+D ++HWP Sbjct: 71 AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP-------- 122 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 +P Q G YV+++ A+ + G ++S+ V+NF + L ++ + PV+N Sbjct: 123 -WP--QKGL-------YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLN 172 Query: 587 QVECHPYLNQ 616 QVE HP +Q Sbjct: 173 QVELHPGFSQ 182 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 140 bits (338), Expect = 3e-32 Identities = 77/197 (39%), Positives = 112/197 (56%), Gaps = 3/197 (1%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 V ++G P+ GLGT + + A++ G HID ++VY NE+ +G+ + Sbjct: 30 VYRLSSGHNFPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWF 89 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDGS 406 +G RED+F+TSKL + P+ V ++ +L+ L +QYLD+YLIH P A +KED Sbjct: 90 AKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSY 148 Query: 407 LFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 T++ G + + D + WK ME VKEG KSIG+SNFN Q+ +L+ A +KP Sbjct: 149 ELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSN 208 Query: 584 NQVECHPYLNQKRLKEF 634 QVE H Y QK L EF Sbjct: 209 LQVEVHAYHQQKPLIEF 225 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 139 bits (337), Expect = 4e-32 Identities = 76/193 (39%), Positives = 111/193 (57%), Gaps = 1/193 (0%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P++ +G +P GLG W++ E AV A+++GYR ID A +Y NE+ VG+A Sbjct: 5 PLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA---- 60 Query: 230 IKEGVVTREDLFITSKLWN-TFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 +K V R++LFIT+KLWN H P + AL+ +L L + Y+DLYLIHWP K+D Sbjct: 61 LKAAAVARDELFITTKLWNDDQHNP---QQALETSLQKLQLDYVDLYLIHWPDP-KQD-- 114 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 YV W+ + L ++GL++SIGV NF+ L+RL+ + P VN Sbjct: 115 ---------------HYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVN 159 Query: 587 QVECHPYLNQKRL 625 Q+E HP L Q++L Sbjct: 160 QIELHPLLQQRQL 172 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 138 bits (335), Expect = 8e-32 Identities = 76/189 (40%), Positives = 110/189 (58%), Gaps = 4/189 (2%) Frame = +2 Query: 77 TIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 T+P G+GT + E T A+ AI++GYRH D A +Y E V EA+ ++ G+V Sbjct: 17 TMPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLV 76 Query: 248 -TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 +R D+F+TSKLW + V A +ETL NL + Y+DL L+HWP FP + Sbjct: 77 ASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 D++ V W+ ME + GL ++IGVSNF++K+LE+LL A V+P NQVE +P Sbjct: 137 EEMAPAFDMEGV--WRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNP 194 Query: 605 YLNQKRLKE 631 Q+ L+E Sbjct: 195 MWQQRTLRE 203 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 138 bits (333), Expect = 1e-31 Identities = 77/198 (38%), Positives = 115/198 (58%), Gaps = 1/198 (0%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 K+P++ F G +IP G GT++ + + V +A+ IGY HID A VY NE+++ + I Sbjct: 12 KVPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIH 71 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 + + REDLFITSK+ + + A+Q+ L LN++YLD LIHWP K Sbjct: 72 NPAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK--- 126 Query: 404 SLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580 L P D ++ +I+ ++TWKA+ L K G++K IGVSNFN L+ L++ + KP Sbjct: 127 -LPPNDPKNAQIR------LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPE 179 Query: 581 VNQVECHPYLNQKRLKEF 634 +NQ E HP K+ EF Sbjct: 180 MNQFEIHPLCFNKKTIEF 197 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 137 bits (332), Expect = 2e-31 Identities = 79/195 (40%), Positives = 105/195 (53%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 M +IP VT ++G TIP G GT++ + QA+ +AID GYR ID AY Y NE VGE Sbjct: 1 MVNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGE 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 A ++ RE L ITSKL +H D +QE+L N+ Y DLYLIHWP Sbjct: 61 A----VRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPN--- 113 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 D+ YV+ W+A+ + G ++SIGV NF + LERL Q Sbjct: 114 --------------PIQDI-YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGEL 158 Query: 575 PVVNQVECHPYLNQK 619 P +NQ+E HP+ NQ+ Sbjct: 159 PTINQIELHPFFNQE 173 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 137 bits (332), Expect = 2e-31 Identities = 77/189 (40%), Positives = 108/189 (57%), Gaps = 1/189 (0%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 T +G +P+ G G ++ + G QAV DAI GYR ID A YGNE+EVGEAI I Sbjct: 5 TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 +G+V RE+LF+TSK+W A+Q +L LN+ YLDLYLIH P Sbjct: 65 QGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP----------- 113 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 ++DV W+AME + G +K+IGVSNF+ QL L + + +KP++NQ+E Sbjct: 114 --------YNDV--FGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIE 163 Query: 596 CHPYLNQKR 622 +P+ K+ Sbjct: 164 VNPFQQNKK 172 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 136 bits (330), Expect = 3e-31 Identities = 81/193 (41%), Positives = 113/193 (58%), Gaps = 3/193 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAV-KDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 N+G IP+ G GT+K+ E +++ K A+ +GYR ID +Y NE+ VG+AI ++ G Sbjct: 6 NDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---G 62 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 V+ RE++F+T+KLW R AL E+L L++ Y+DLYLIHWP Sbjct: 63 VL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWP------------- 108 Query: 422 QSGKIQFSD--VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 + I + D DTW+AME L EG +KS+GVSNF + LE L Q A V P VNQ+E Sbjct: 109 -ANAINYKDWQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIE 167 Query: 596 CHPYLNQKRLKEF 634 HP Q ++ EF Sbjct: 168 FHPGYWQPQVTEF 180 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 136 bits (330), Expect = 3e-31 Identities = 72/197 (36%), Positives = 106/197 (53%), Gaps = 4/197 (2%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217 +P G T+P G+GT+ S P EV AV A+ GYR +DCA VYGNE +VGEA Sbjct: 13 VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72 Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397 + + G V R++LF+ SK+WN H P ++ +L +L + +LD +HWP Sbjct: 73 LAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPNHH 131 Query: 398 DGSLFPTDQSGKIQFSDVD-YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 + + + D D Y+ W A+E LV GLV+ +G SN +L+ LL+ A + Sbjct: 132 PPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDARIP 191 Query: 575 PVVNQVECHPYLNQKRL 625 P +N++E HP Q L Sbjct: 192 PALNEMELHPCFQQPEL 208 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 136 bits (329), Expect = 4e-31 Identities = 85/188 (45%), Positives = 106/188 (56%), Gaps = 1/188 (0%) Frame = +2 Query: 74 ETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250 ETIP GLG ++ E + AV+ AI++GYR D A VY NE VG+AI + V Sbjct: 15 ETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVP 70 Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430 RE+LFI+SK+WN D A + TL NL + YLDLYLIHWP A K Sbjct: 71 REELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK------------ 118 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610 Y D+W+AME L E L+KSIGV+NF L LL A KPV+NQVE HP L Sbjct: 119 --------YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLL 170 Query: 611 NQKRLKEF 634 Q L+++ Sbjct: 171 PQNDLRKY 178 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 136 bits (329), Expect = 4e-31 Identities = 91/223 (40%), Positives = 120/223 (53%), Gaps = 12/223 (5%) Frame = +2 Query: 2 SSQAAAKIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGE--VTQAVKDAIDIGYRHID 175 S +A+II ++ + + T P GLGT++ G V +AV A+ GYRHID Sbjct: 21 SLSTSAEIIPELVHRFSFFPVSE-MTFPAVGLGTFQGDAGNRGVKEAVLQALRCGYRHID 79 Query: 176 CAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQY 355 A YGNE EVGEAI KE + RE++ +T+KL T+HR V AL +L+ L + Y Sbjct: 80 TATAYGNEIEVGEAI----KESRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNY 135 Query: 356 -LDLYLIHW-----PQAYKE--DGSLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEGLV 505 L ++L P AY D + I ++ DY TW AME LV +G + Sbjct: 136 GLSMHLYSASSYSVPHAYSPGPDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKL 195 Query: 506 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 K IGVSNFN +LERLL A + P VNQ+E HPYL Q L F Sbjct: 196 KMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVRF 238 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 136 bits (328), Expect = 5e-31 Identities = 80/207 (38%), Positives = 112/207 (54%), Gaps = 13/207 (6%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT-- 223 P ++ NNG I G G +K P + V A++ GYRH D A +YGNE VG+AI Sbjct: 5 PRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGAL 64 Query: 224 -----------SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYL 370 S ++REDLF+T+K+WN H D A ++ NL ++Y+DLYL Sbjct: 65 AGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYL 124 Query: 371 IHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLER 550 IHWP A + LF ++++AME L +EG +++IGVSNF LE Sbjct: 125 IHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGVSNFQPAHLEH 166 Query: 551 LLQHATVKPVVNQVECHPYLNQKRLKE 631 LL+ A V P VNQ+E HP+L Q L++ Sbjct: 167 LLETAEVVPAVNQIELHPWLQQDELRQ 193 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 134 bits (324), Expect = 2e-30 Identities = 74/196 (37%), Positives = 106/196 (54%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP G IPV G GT+K P + AV A+++GYRHID A +YGNE EVG A Sbjct: 16 IPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAA--- 72 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 ++ + REDLFIT+K+ N+ H PD +++ +L++L Y+DL L+HWP Sbjct: 73 -LEASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP-------- 123 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 PT G D W A+E G ++IG+SN+ + +E + + ATV P V Sbjct: 124 -LPTLYGG-------DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVL 175 Query: 587 QVECHPYLNQKRLKEF 634 QVE HP+ L+ + Sbjct: 176 QVESHPFFPNADLRAY 191 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 133 bits (322), Expect = 3e-30 Identities = 79/201 (39%), Positives = 117/201 (58%), Gaps = 4/201 (1%) Frame = +2 Query: 44 KIPVVTFN---NGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVG 211 KI V+ +N N +P G GT+K + G+ T +AVK A+++GYRH+DCA +Y N+ V Sbjct: 7 KIKVMKYNLLANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVS 66 Query: 212 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391 + I K V R+++FITSK+WN + + A + L +L+++YLDL LIHWP Sbjct: 67 QGI----KLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPI-- 120 Query: 392 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571 G F K + +V+ TWKAME EG +K+IG+SNF +E L + A + Sbjct: 121 ---GKGF------KDNWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKI 170 Query: 572 KPVVNQVECHPYLNQKRLKEF 634 P+VNQ+E HP Q + E+ Sbjct: 171 LPMVNQLEFHPGYLQPEIVEY 191 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 132 bits (320), Expect = 5e-30 Identities = 85/228 (37%), Positives = 114/228 (50%), Gaps = 29/228 (12%) Frame = +2 Query: 38 APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAID-----------------IGYR 166 AP N G IPV GLGTW+S PGEV +AV+ AI +GY Sbjct: 8 APGQKTFKLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYV 67 Query: 167 HI----------DCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRG 316 + D A++YGNE EVG+ I K V R +LF+T+K+W T+HR Sbjct: 68 ALHPLYIPFLAKDAAWIYGNENEVGQGI----KASGVPRSELFVTTKIWCTYHRQP--EA 121 Query: 317 ALQETLDNLNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLV 490 L E+L L + Y+DL L+HWP K P ++ G D TW+ ME L Sbjct: 122 CLDESLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLP 181 Query: 491 KEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 G K+IGVSN++ L++LL A + P NQVE HP+L Q L ++ Sbjct: 182 ATGKTKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKY 229 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 132 bits (319), Expect = 7e-30 Identities = 77/190 (40%), Positives = 103/190 (54%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 +NG +IP G GT+K+ G+ + + +AI GYRH D A YG E +G+A+ E Sbjct: 11 SNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ESD 65 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + RED F+TSKLW T D A TL+ L YLDLYLIHWP+ E D+ Sbjct: 66 IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDLELEDWAKLDR 125 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 +TW+A+E L + GLV++IGVSNF LE +L A V P+V+Q+E HP Sbjct: 126 ------------ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHP 173 Query: 605 YLNQKRLKEF 634 Q F Sbjct: 174 GYTQDEAVAF 183 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 132 bits (318), Expect = 9e-30 Identities = 77/204 (37%), Positives = 114/204 (55%), Gaps = 8/204 (3%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 208 I V NNG +P+ GLGT + E+T + +A+D GYR+ D A Y NE E+ Sbjct: 12 IKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEI 71 Query: 209 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388 G+A + ++G RED+FIT+KL+ F ++ +Q +LD L Y+DLYLI W Sbjct: 72 GQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQW--- 127 Query: 389 YKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 S P T+ G + + + W+ +E V+ G+++SIGV+NFN + + LL + Sbjct: 128 -----SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSY 182 Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634 A +KPVVNQ+E PYL Q L F Sbjct: 183 AKIKPVVNQIEVTPYLPQIDLINF 206 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 132 bits (318), Expect = 9e-30 Identities = 73/196 (37%), Positives = 106/196 (54%), Gaps = 1/196 (0%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P + NNG IP GLG WK+ E Q VK+AI Y ID A YGNE VG+ I Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70 Query: 230 IKEGVVTREDLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 K R+ +F+T+K++N D +R A+ E L L Y+DL L+HWP K Sbjct: 71 FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDK---- 126 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 Y ++W+A+E + K+G K+IGV NFN +++ LL HA +KP +N Sbjct: 127 ----------------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAIN 170 Query: 587 QVECHPYLNQKRLKEF 634 Q+E +P ++Q ++ +F Sbjct: 171 QIEFNPLIHQPKIVKF 186 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 131 bits (317), Expect = 1e-29 Identities = 69/193 (35%), Positives = 109/193 (56%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 PV+ F++G IP G G W+ + V+ AI+IGYR ID AY+Y NE +GE Sbjct: 5 PVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG---- 60 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 ++ + R+++F+T+K+WN R +++ +L + V+ LDL LIHWP Sbjct: 61 LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP--------- 111 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 + D+ Y++TWKA + + EGL++SIG SNFN+ LER++ PV+NQ Sbjct: 112 --------VPSQDL-YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQ 162 Query: 590 VECHPYLNQKRLK 628 +E +P L Q ++ Sbjct: 163 IELNPMLQQPEMR 175 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 130 bits (315), Expect = 2e-29 Identities = 79/191 (41%), Positives = 109/191 (57%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 K+P V NNG +P G+GT+ K + V AI +G+R ID A YGNEKEVGE I Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGEGIC 86 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 + G+ RE LFIT+K+ R VR +L ++L +L Y+DL LIHWP Sbjct: 87 ---RSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP------- 135 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 G I+ +TW+ +E V +G ++SIGVSNFN L+ LL++A ++PVV Sbjct: 136 ------VKGHIK-------ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVV 182 Query: 584 NQVECHPYLNQ 616 NQ+E PY+ Q Sbjct: 183 NQIEIEPYMTQ 193 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 130 bits (315), Expect = 2e-29 Identities = 75/189 (39%), Positives = 99/189 (52%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 PV+ N+G IP GLGTW +V AV +A++ GYRHID A YGNEK VG I S Sbjct: 5 PVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIRS- 63 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 + R +LFIT+KL F D L +L L + Y+DL LIHWP ++ Sbjct: 64 ---SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD---- 116 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 +++ TWK E L +G V+SIGVSNF LERL+ V P VNQ Sbjct: 117 --------------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQ 162 Query: 590 VECHPYLNQ 616 ++ P + + Sbjct: 163 IQVSPAITR 171 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 130 bits (315), Expect = 2e-29 Identities = 81/211 (38%), Positives = 112/211 (53%), Gaps = 9/211 (4%) Frame = +2 Query: 29 SKMAPKIPVVTFNNGETIPVFGLGT---WKSKPG------EVTQAVKDAIDIGYRHIDCA 181 S P P V N+ +IP+ G GT W + G E+ +A+K AI +GYRH+D A Sbjct: 3 SNSIPNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGA 62 Query: 182 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLD 361 VYG E E+G A IKE + RE+LF+T+K+ + A+ ++L L + Y+D Sbjct: 63 EVYGTEAELGVA----IKESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVD 115 Query: 362 LYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQ 541 LYLIH P K DG L W AME + + G K+IGVSN++ Sbjct: 116 LYLIHSPFFAKSDGEL----------------QQAWAAMEKVQQAGKAKAIGVSNYHQSH 159 Query: 542 LERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 LE L+ A + PV+NQ+E HPYL Q+ L F Sbjct: 160 LEATLKTAVIAPVINQIEHHPYLQQEELLRF 190 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 130 bits (315), Expect = 2e-29 Identities = 92/212 (43%), Positives = 118/212 (55%), Gaps = 8/212 (3%) Frame = +2 Query: 23 IISKMAPKIPVVTFNNGETIPVFGLGT--WKSKPGEVTQ----AVKDAIDIGYRHIDCAY 184 +I+ M PKIPV P +G+GT +K + GE+ + +VK+A+ G+ HIDCA Sbjct: 2 LIAAMGPKIPV---------PAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAE 52 Query: 185 VYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 364 VYGNE+EVG A+ KE V R LFITSK+ H D + AL E+L L YLDL Sbjct: 53 VYGNEEEVGVAL----KEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDL 105 Query: 365 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544 YL+H P + E KI S+ WKAME + GLV S+GVSNF L Sbjct: 106 YLLHSPIPFYEK----------KIPISE-----GWKAMETALGTGLVHSVGVSNFRIPDL 150 Query: 545 ERLLQHATVKPVVNQVECHP--YLNQKRLKEF 634 E LL+ +T+ P VNQ+E HP Y K L EF Sbjct: 151 EELLKTSTITPRVNQIEFHPQVYKAAKPLVEF 182 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 130 bits (314), Expect = 3e-29 Identities = 75/197 (38%), Positives = 105/197 (53%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 MA K P++ NNG +P GLG + + E A+ AI GYR ID A Y NE +VGE Sbjct: 1 MAGKSPLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGE 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 I+ V R ++F+T+KL+N + + A E+L L + Y+DLYL+HWP Sbjct: 61 G----IRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP---- 112 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 574 D + IQ +WKA E ++ +G ++IGV NF QL+ L+ + V Sbjct: 113 ------TKDWNATIQ--------SWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVV 158 Query: 575 PVVNQVECHPYLNQKRL 625 P VNQ+E HPY QK L Sbjct: 159 PAVNQIELHPYFAQKPL 175 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 130 bits (313), Expect = 4e-29 Identities = 75/182 (41%), Positives = 101/182 (55%), Gaps = 1/182 (0%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI-TSKIK 235 T NNG IP GLGTW+ V AV++A +GYRHID A YGNE+ VGEA+ SKIK Sbjct: 16 TLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVRKSKIK 75 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 RE+LFITSK+ + ++ +L + + ++DL LIH PQ + F Sbjct: 76 -----REELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS----FR 126 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 K + V+ + A+E K G V+SIGVSNF K LE +L++ KP NQ+ Sbjct: 127 KGDYFK------ENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQIL 180 Query: 596 CH 601 CH Sbjct: 181 CH 182 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 130 bits (313), Expect = 4e-29 Identities = 66/191 (34%), Positives = 116/191 (60%), Gaps = 2/191 (1%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 NG+ IP LGT+++K ++ AV +A+ +GYR D A Y NEK++G A+ + + + Sbjct: 6 NGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRHNI 65 Query: 248 TREDLFITSKL--WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 ED+++TSK+ +++ + +L+R + E+L+ L+ +YLDL L+H+P+ P D Sbjct: 66 CSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR---------PLD 116 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 + + + DTW A+E L EG ++SIGVSN+ +E + + T++P VNQ+E H Sbjct: 117 TEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIEYH 176 Query: 602 PYLNQKRLKEF 634 P+ +K L+ + Sbjct: 177 PHFQRKVLRAY 187 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 129 bits (312), Expect = 5e-29 Identities = 72/178 (40%), Positives = 99/178 (55%), Gaps = 1/178 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 + NNG IP+FG GT+K K E +V+ A+ GYRHID A Y NEK V AI + Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFM 67 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 +E RED+F+TSK W T D A ++T++ + + YLDLYL+HWP +Y D Sbjct: 68 EESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWE 127 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 T++ TWKAM + K G VK+IGVSNF + L+ ++ V P V+ Sbjct: 128 NTNR------------QTWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID-MEVTPAVD 172 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 129 bits (311), Expect = 6e-29 Identities = 71/194 (36%), Positives = 103/194 (53%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P + N+G IP G GTW+ + + QAV AID+GY ID A +YGNEK VG Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG------ 58 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 +GV D+F+ +K+WN D A ++ L+ L +++D+ LIHWP K+ Sbjct: 59 --KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD---- 112 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 +VDTWKA+ L G KSIGVSNF + L+R++ V P +NQ Sbjct: 113 --------------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQ 158 Query: 590 VECHPYLNQKRLKE 631 +E HP Q+ +++ Sbjct: 159 IELHPSFQQRDMRK 172 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 129 bits (311), Expect = 6e-29 Identities = 79/193 (40%), Positives = 102/193 (52%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP +T NNG IP G G ++ P E + V+DA++ GYRHID A Y NE VG AI++ Sbjct: 9 IPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAISA 68 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 + RED+FIT+KL N A Q + L V+++DLYLIHWP Sbjct: 69 ----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHWPVP------ 116 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 S Y + WKAME L +++IGVSNF + L+ LL A V P VN Sbjct: 117 ------------SQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVN 164 Query: 587 QVECHPYLNQKRL 625 QVE HP Q+ L Sbjct: 165 QVEIHPTFQQQEL 177 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 129 bits (311), Expect = 6e-29 Identities = 76/194 (39%), Positives = 109/194 (56%), Gaps = 4/194 (2%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 N G IP+ G GT++ E+ V D A++ GYRHID A VY NE+ +G A+ + + + Sbjct: 37 NTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPKY 96 Query: 242 VVTREDLFITSKLWNTFHRPD-LVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 + RED+FITSKL + + + V ++++L NL YLDLYLIHWP + G Sbjct: 97 NLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWKWL 156 Query: 419 DQSGKIQFSDVDY-VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVNQV 592 +V Y +W A+ L +EG ++SIGVSN+ K L+ +L + P VNQV Sbjct: 157 FGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVNQV 216 Query: 593 ECHPYLNQKRLKEF 634 E HPY Q L E+ Sbjct: 217 EWHPYYYQPELLEY 230 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 128 bits (310), Expect = 8e-29 Identities = 69/176 (39%), Positives = 101/176 (57%), Gaps = 1/176 (0%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NG IP GLGTW+ GE T AV A+ GYRHID AY Y NE+ VG+A+ ++ Sbjct: 12 NGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGKAV----RDSG 67 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + R D+F+TSKL D ET+ N ++ LDLYLIH P + E G+ + + Sbjct: 68 IDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKGADYTKEN 127 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 ++ WKAME + + G ++IGVSNF+ L+ ++++A +KP+VNQ+ Sbjct: 128 -----------IEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 127 bits (307), Expect = 2e-28 Identities = 71/198 (35%), Positives = 108/198 (54%) Frame = +2 Query: 38 APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217 A IP V+ N+G +IPV GLG + E ++V A++ GYR ID A VYGNE VG A Sbjct: 8 AAGIPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRA 67 Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397 + + + RE++++T+KL + A + +L+ L + Y+DLYLIHWP Sbjct: 68 VNAS----GIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAG--- 120 Query: 398 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577 GK Y+D+W + ++G+ +SIGV NFN++ L ++ + P Sbjct: 121 --------DHGK-------YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTP 165 Query: 578 VVNQVECHPYLNQKRLKE 631 +NQ+E HP LNQ L+E Sbjct: 166 AINQIELHPLLNQAELRE 183 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 127 bits (307), Expect = 2e-28 Identities = 74/191 (38%), Positives = 112/191 (58%), Gaps = 1/191 (0%) Frame = +2 Query: 65 NNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 NNG+ +P+ GLGT+ + E+T ++ A+D GYRHID A Y NE +GE++ + KEG Sbjct: 11 NNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKEG 70 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 +R+DLFI SK++ ++ + +++++L L + Y+DLY +H+P + Sbjct: 71 KYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGF---------- 118 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 S K +F + W +E + GL KSIGVSNFN L LL +A VKPV NQVE Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVS 178 Query: 602 PYLNQKRLKEF 634 ++ QK L +F Sbjct: 179 VFIQQKNLIKF 189 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 127 bits (306), Expect = 3e-28 Identities = 73/195 (37%), Positives = 108/195 (55%), Gaps = 1/195 (0%) Frame = +2 Query: 53 VVTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 V+T +NG+ +P FGLG+ + + EVT ++ A+D+GYRHID A +Y NE+ +G A+ + Sbjct: 9 VITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTI 68 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 EG RED+F+ +K + ++E L L V Y+DL LIH P A Sbjct: 69 FGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLA------- 119 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 P+D + V + W E + GL K +GVSNFN + + LL + +KP+VNQ Sbjct: 120 APSDDYQQWNHKPVHQI--WAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQ 177 Query: 590 VECHPYLNQKRLKEF 634 +E H + QK L EF Sbjct: 178 IELHVFNQQKNLVEF 192 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 127 bits (306), Expect = 3e-28 Identities = 75/192 (39%), Positives = 104/192 (54%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T ++G IP FGLG + QAV A++ GYR ID A Y NEK VGEA ++E Sbjct: 8 TLSDGYKIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA----LRE 63 Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 V R ++++ +K+++T H + A +L L V Y+DLYLIH+P Sbjct: 64 SAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFP------------ 111 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 V +W+AM L +GL +SIGVSNFN LE L +H+ + PVVNQ+E Sbjct: 112 --------VPAGVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEV 163 Query: 599 HPYLNQKRLKEF 634 HPYL + L +F Sbjct: 164 HPYLQMEELVDF 175 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 126 bits (305), Expect = 3e-28 Identities = 70/182 (38%), Positives = 101/182 (55%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 V NNGE IP LGTW EV + V+ A++IGYR D A YGNE VG+ I + Sbjct: 7 VILNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIWN--- 63 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 + R D+F+T+KL + + A+ LD ++Y+DL LIH PQ + E Sbjct: 64 -SDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIE------ 116 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 +++ F ++ W+AME VK G V+SIGVSNF + +E ++ + T+ P VNQ+E Sbjct: 117 VNRTNDRHFK--GNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIE 174 Query: 596 CH 601 H Sbjct: 175 VH 176 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 126 bits (305), Expect = 3e-28 Identities = 73/190 (38%), Positives = 102/190 (53%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 +P + N+G+T P GLG W+ + +V+ AI+ GYRHID A +YGNE+ VG A+ Sbjct: 8 VPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGRAVAD 67 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 +K G V RE+LFIT+KLWN + A E+ L + Y+DLYL+HWP Sbjct: 68 AVKAGDVQREELFITTKLWNADQA--CGKEAFAESQKKLGMDYVDLYLLHWP-------- 117 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 P S +V + +M + + G SIGV NF + L+ L Q A P VN Sbjct: 118 -CPQADS---------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQ-AGHTPAVN 166 Query: 587 QVECHPYLNQ 616 Q+E HP +Q Sbjct: 167 QIEIHPGFSQ 176 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 126 bits (305), Expect = 3e-28 Identities = 77/205 (37%), Positives = 118/205 (57%), Gaps = 5/205 (2%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 M PK +NG IP LGT+ + + V + + GYRH D A +YGNEKEVG+ Sbjct: 1 MVPKF--YKLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGD 58 Query: 215 AITSKIKE--GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLN-VQYLDLYLIHWPQ 385 I + E G RE++F T+KLWN+ + + A+++ L+ ++ +QY+DL LIH P Sbjct: 59 GIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL 118 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 +GS K++ ++TW+AM+ V EGLVKSIGVSN+ K ++ LL Sbjct: 119 ----EGS--------KLR------LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWP 160 Query: 566 TV--KPVVNQVECHPYLNQKRLKEF 634 + KPVVNQ+E P++ ++ L ++ Sbjct: 161 ELKHKPVVNQIEISPWIMRQELADY 185 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 126 bits (304), Expect = 4e-28 Identities = 70/186 (37%), Positives = 106/186 (56%), Gaps = 1/186 (0%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDA-IDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256 +P+ G+GTW+ + E+ + V DA GYR ID A VY NE ++G + + + RE Sbjct: 11 MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRE 70 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436 D++ITSKL + R +++E+L NL V+YLDL LIHWP GS ++ Sbjct: 71 DIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP------GSSLKSENPANK 124 Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616 + V++W M ++ EG ++S+GVSNF LE L + + V P VNQVE HP+ +Q Sbjct: 125 KLR----VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQ 180 Query: 617 KRLKEF 634 L ++ Sbjct: 181 DDLVKY 186 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 126 bits (303), Expect = 6e-28 Identities = 76/197 (38%), Positives = 104/197 (52%), Gaps = 1/197 (0%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 220 K P +T N+G IP G GT++ G QAVK+A+ IGYRHID A Y NE EVG+A Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQA- 61 Query: 221 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 400 IK+ + R+ +++TSKLW + D A+ +L L + Y+DLYLIH P Sbjct: 62 ---IKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP------ 112 Query: 401 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580 + DV W+AME K G +KSIGVSN ++ + P Sbjct: 113 -------------YGDVP--GAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPA 157 Query: 581 VNQVECHPYLNQKRLKE 631 VNQVE +PY Q+ L++ Sbjct: 158 VNQVEFNPYFQQQPLRQ 174 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 126 bits (303), Expect = 6e-28 Identities = 70/193 (36%), Positives = 106/193 (54%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 +T NN IP+FG GT++ P + QAV A + GYR ID A Y NE++VGEA +K Sbjct: 4 LTLNNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA----VK 59 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 + R+++FIT+K + + L E+L + + Y DL LIHWP + Sbjct: 60 ASGLNRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD------- 110 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 +DTW A+E K G ++IG+SNFNS+Q L+ ++V+P+V+Q+E Sbjct: 111 --------------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIE 156 Query: 596 CHPYLNQKRLKEF 634 H +L Q ++ EF Sbjct: 157 THLFLQQWKMHEF 169 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 126 bits (303), Expect = 6e-28 Identities = 80/194 (41%), Positives = 110/194 (56%), Gaps = 1/194 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 + N+G IP FGLG ++ GE T+ AVK+A+ +GYRHID A+ Y NE+ VG AI S Sbjct: 5 IVLNDGNIIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS-- 62 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 G+ E ++ITSKLW + + D A++ L+ LN++ +DL L+H Sbjct: 63 -SGIPISE-IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLH------------ 106 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 Q G +Y W A+E VK G VKSIG+SNF+ ++L L A +KP QV Sbjct: 107 --QQVG-------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQV 157 Query: 593 ECHPYLNQKRLKEF 634 E HPY QK L+EF Sbjct: 158 ETHPYHQQKELQEF 171 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 126 bits (303), Expect = 6e-28 Identities = 83/196 (42%), Positives = 110/196 (56%), Gaps = 14/196 (7%) Frame = +2 Query: 47 IPVVTFNN-GETIPVFGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 IP +T + G+ IP+ G+ T + P E + ++ AI++GYRH DC Y +EK +GE Sbjct: 4 IPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGE 63 Query: 215 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETL---------DNLNVQYLDL 364 AI +K G++ +R++LFITSKLW + D V ALQ TL NL + YLDL Sbjct: 64 AIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLDL 123 Query: 365 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544 YLIHW DG L +D WKAME K L K+IGVSNF+ +L Sbjct: 124 YLIHW-----SDGHL------------PIDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKL 166 Query: 545 ERLLQHATVKPVVNQV 592 E LLQ A++ P VNQV Sbjct: 167 EELLQTASILPAVNQV 182 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 125 bits (302), Expect = 8e-28 Identities = 75/186 (40%), Positives = 101/186 (54%), Gaps = 2/186 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 +N +P+ G G ++ +V Q+V +AI GYR ID A VYGNE VGEA+ I EG Sbjct: 12 SNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEG 71 Query: 242 VVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 + TRE+LFITSKLW D+ ++ +L ++Y DLYL+H QA + Sbjct: 72 LCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH--QAMR-------- 121 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 DY W+A+E +EG +K+IGVSNF L + VKP+VNQVE Sbjct: 122 -----------DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVEL 170 Query: 599 HPYLNQ 616 HPY Q Sbjct: 171 HPYFAQ 176 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 124 bits (299), Expect = 2e-27 Identities = 68/187 (36%), Positives = 106/187 (56%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 +G +P+ GLG +++ P E T AV++A+ +GYRHID A YGNE+EVGE I+ + Sbjct: 25 SGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEG----IRRAGI 80 Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 427 R+++FI +K+W + + D A ++ L V +DL L+H P D +L Sbjct: 81 ARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRTL------ 134 Query: 428 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607 ++A+E L+ +G V++IGVSNF + L RLL ++ P VNQ+E HPY Sbjct: 135 -----------GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPY 183 Query: 608 LNQKRLK 628 Q+ L+ Sbjct: 184 FQQRALQ 190 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 124 bits (299), Expect = 2e-27 Identities = 83/216 (38%), Positives = 111/216 (51%), Gaps = 27/216 (12%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 +G IP GLGTW+S V ++ GYRHID A+ YG+++EVG+ I + G+ Sbjct: 20 SGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAGL- 78 Query: 248 TREDLFIT----------------SKLWN-----------TFHRPDLVRGALQETLDNLN 346 R DLF+T S L N T P+ VR ALQ TL L Sbjct: 79 ERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKELQ 138 Query: 347 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 526 ++YLDLYLIHWP +E S P ++G + D D W+ ME L K+ LV++IGV N Sbjct: 139 LEYLDLYLIHWPIRLREGASKPP--KAGDVL--DFDMEGVWREMENLSKDSLVRNIGVCN 194 Query: 527 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 F +L +LL A + P V Q+E HP R+ EF Sbjct: 195 FTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEF 230 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 124 bits (298), Expect = 2e-27 Identities = 70/196 (35%), Positives = 112/196 (57%), Gaps = 3/196 (1%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 V ++G +P+ G GT+K + E V Q V +++++G+R ID A Y NE+++G A+ + + Sbjct: 8 VCLSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLL 67 Query: 233 KEGVVTREDLFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 + + R D+FIT+KL + + P + +Q++L N Y+DLYLIHWP A + Sbjct: 68 PKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATR----- 122 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPVVN 586 P + TW + L K+G ++SIGVSNF K L+ LLQ+ + P VN Sbjct: 123 IPETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVN 178 Query: 587 QVECHPYLNQKRLKEF 634 QVE HP+ Q+ L ++ Sbjct: 179 QVELHPHYRQEELIKY 194 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 124 bits (298), Expect = 2e-27 Identities = 71/196 (36%), Positives = 104/196 (53%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP + ++G +IP G GT+ K + + A+ GYR +D A+ Y NE VG A+ Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAAV-- 79 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 ++ + R+++FITSKL H D ++E+L + YLDLYLIHW Sbjct: 80 --RQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHW--------- 128 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 P Q G Y++ W+A+ K+G ++SIGVSNF K +E L + V PV+N Sbjct: 129 --PNPQQGL-------YIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVIN 179 Query: 587 QVECHPYLNQKRLKEF 634 QVE HPY NQ + + Sbjct: 180 QVELHPYFNQAEQRAY 195 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 124 bits (298), Expect = 2e-27 Identities = 76/186 (40%), Positives = 102/186 (54%), Gaps = 1/186 (0%) Frame = +2 Query: 80 IPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256 +P+ GLG +K+ E A+ A+ GYR +D A Y NE+ VG I K GV R+ Sbjct: 1 MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIA---KCGV-PRK 56 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436 DLFIT+K+WN R V GA Q +LD L + Y+DLYLIHWP G Sbjct: 57 DLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP----VPGC---------- 102 Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616 +++TWK ME +++ G SIGVSNF + LE L + + + P VNQ+ECHP Sbjct: 103 ------FLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYP 156 Query: 617 KRLKEF 634 K L E+ Sbjct: 157 KELIEY 162 >UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phytophthora infestans|Rep: Aldo-keto reductase, putative - Phytophthora infestans (Potato late blight fungus) Length = 255 Score = 124 bits (298), Expect = 2e-27 Identities = 71/201 (35%), Positives = 112/201 (55%), Gaps = 1/201 (0%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211 M+ +P +G IP+ GLG ++S+PG E A+ ++ +GYRHID A +YGNE++VG Sbjct: 1 MSVNVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVG 60 Query: 212 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 391 A +++ + RE++F+T+KL+ T A + + D L + Y+ LYL+H P Sbjct: 61 RA----VRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPP 116 Query: 392 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 571 KE DTW+A+E L ++ ++ IGVSNFN L L + A + Sbjct: 117 KE-------------------RADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHI 157 Query: 572 KPVVNQVECHPYLNQKRLKEF 634 KP VNQVE HP++ ++ L + Sbjct: 158 KPAVNQVELHPWMMRQSLVNY 178 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 123 bits (296), Expect = 4e-27 Identities = 69/183 (37%), Positives = 96/183 (52%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 NG IP G GTW+ + + + V A+ GYRHID A +YGNE VG+ K+ V Sbjct: 8 NGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG----WKQSGV 63 Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 427 RED F+T+K+W R ++ +++E+LD L Y+DL L+HWP Sbjct: 64 KREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP--------------- 108 Query: 428 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607 +V +T KAM + + G V+ IGVSNF L+ H+ V NQVE HPY Sbjct: 109 ----VPEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPY 164 Query: 608 LNQ 616 L+Q Sbjct: 165 LDQ 167 >UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspergillus fumigatus|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 350 Score = 123 bits (296), Expect = 4e-27 Identities = 72/164 (43%), Positives = 94/164 (57%), Gaps = 7/164 (4%) Frame = +2 Query: 155 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETL 334 +GYRHID A V NE EVG K+ V RE +F+TSKLWNT H P V AL +T+ Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGW----KKLGVPREGIFLTSKLWNTHHHPSHVEEALDKTV 127 Query: 335 DNLNVQYLDLYLI----HWPQAYKEDGSLFPTDQSGKIQFS--DVDYVDTWKAMEPLVKE 496 +L YLDLYL+ H Y+ P + G +F D+ DTW A E LV Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184 Query: 497 GLVKSIGVSN-FNSKQLERLLQHATVKPVVNQVECHPYLNQKRL 625 G ++S+GVSN F +++E LL A + P VNQ+E HPYL Q ++ Sbjct: 185 GKIRSLGVSNLFTIEKMEELLNTADIPPAVNQIEAHPYLLQPKI 228 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 123 bits (296), Expect = 4e-27 Identities = 79/199 (39%), Positives = 111/199 (55%), Gaps = 4/199 (2%) Frame = +2 Query: 50 PVVTFN--NGETIPVFGLGTWKSKPG--EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217 P +F NG T+P GLGT++ G +V VK AI GYRHID A YGNE+ +G+A Sbjct: 4 PTASFRLVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDA 63 Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397 I KE ++R++L ++ W H P V AL +L+ L ++Y+ P AY Sbjct: 64 I----KESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV-------PHAYLP 106 Query: 398 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577 + ++S K Y +TW+AME LV G K+IG+SNFN + +R+L+ A ++P Sbjct: 107 GPNNVDYERSRK-------YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRP 159 Query: 578 VVNQVECHPYLNQKRLKEF 634 VNQVE HPY Q L F Sbjct: 160 AVNQVEAHPYFPQHELLAF 178 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 122 bits (294), Expect = 7e-27 Identities = 79/205 (38%), Positives = 111/205 (54%), Gaps = 1/205 (0%) Frame = +2 Query: 20 KIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGN 196 K S A P V +NG IP+ GLGT G +AV A+ + G RHID A YG Sbjct: 4 KPTSCTALSCPAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGC 62 Query: 197 EKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIH 376 E+ +G+A+T E V RE+L++T+KLW + + A +++ L V YLDLYL+H Sbjct: 63 EEALGKAVT----ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMH 118 Query: 377 WPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 556 WP S+ P S +++ ++TW+A+E L EGL ++IGVSNF L L Sbjct: 119 WPD------SMVPGRSSQEVR------LETWRALEELYDEGLCRAIGVSNFLIPHLNELK 166 Query: 557 QHATVKPVVNQVECHPYLNQKRLKE 631 + P VNQVE HP+ +L E Sbjct: 167 DSGGIVPHVNQVEFHPFQQPMKLVE 191 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 122 bits (294), Expect = 7e-27 Identities = 70/190 (36%), Positives = 104/190 (54%), Gaps = 1/190 (0%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NG IP GTW+ GE T QAV+ A+ GYRHID A Y NE VG+AI ++ Sbjct: 12 NGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAI----RDSG 67 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + RE +F+T+KL +L NL + Y+DLYL+H P +P Q Sbjct: 68 IPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPWGQ 118 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 G++ D +D W+AME + + G K+IGVSNF + L+ +L AT+ P+VNQ++ + Sbjct: 119 VGRVY--DEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYL 176 Query: 605 YLNQKRLKEF 634 + ++ +F Sbjct: 177 GFTEPKITKF 186 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 122 bits (293), Expect = 1e-26 Identities = 73/196 (37%), Positives = 109/196 (55%), Gaps = 1/196 (0%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 +P V +G +P+ GLGT+K + E + Q+V A+ GYR D A VYGNE +G+ + Sbjct: 3 VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 + + + RED+FI SKL + H G L+ +L+ L+ +Y+DLYLIHWP +G Sbjct: 63 ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGM---EG 118 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 L P D + S+ +W +E G K+IGVSN+ +K + LL V P V Sbjct: 119 -LDPEDS----RHSEYR-AQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAV 172 Query: 584 NQVECHPYLNQKRLKE 631 Q+EC P L Q+ L++ Sbjct: 173 LQIECQPKLIQRELRD 188 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 121 bits (292), Expect = 1e-26 Identities = 78/199 (39%), Positives = 106/199 (53%), Gaps = 9/199 (4%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKP-----GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 N IP GLGT++ P G V +V A+ IGYRHID A YG V I + Sbjct: 11 NTSIRIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAA 69 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 I+ V RED+F+ +KL N FH P+ V + +L NL + Y+ P AY + + Sbjct: 70 IRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTKGENY 122 Query: 410 FPTDQSGKIQFSDVD----YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577 + D++ + TWKAME LV +G K IGVSNF++ +L+RLL + P Sbjct: 123 STVRKPDGKPVVDIELSRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFP 182 Query: 578 VVNQVECHPYLNQKRLKEF 634 VVNQVE +PY QK+L F Sbjct: 183 VVNQVELNPYFPQKQLLRF 201 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 119 bits (287), Expect = 5e-26 Identities = 69/191 (36%), Positives = 105/191 (54%), Gaps = 1/191 (0%) Frame = +2 Query: 65 NNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 241 NNG +P G G +K + + A++ A+D+GYR D A Y NEKE+G+ S Sbjct: 12 NNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS---- 67 Query: 242 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 + R++ F+T+K+WNT D A +++ L + +DLYL+HWP K+D Sbjct: 68 GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------- 117 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 + +TW+A+E L EGLV++IGVSNF + L+RL A V PVV+Q+E H Sbjct: 118 ----------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETH 167 Query: 602 PYLNQKRLKEF 634 P+ + L + Sbjct: 168 PHFPNQLLHRY 178 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 119 bits (287), Expect = 5e-26 Identities = 70/194 (36%), Positives = 109/194 (56%), Gaps = 1/194 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 VT NNG +P G G ++ + Q V+D +++GYR +D A +YGNE+ VG+AI Sbjct: 5 VTLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI---- 60 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 K V RED+FITSK+W + D A +++ L + Y+DLYLIH P Y Sbjct: 61 KHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP--YN------ 112 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 DY TW+A+E L +EG +++IGVS+F +++L L+ VKP VNQ+ Sbjct: 113 -------------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQI 159 Query: 593 ECHPYLNQKRLKEF 634 E + + + + +++ Sbjct: 160 ETNVWNQEWKSQQY 173 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 119 bits (286), Expect = 7e-26 Identities = 86/207 (41%), Positives = 110/207 (53%), Gaps = 22/207 (10%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCA---YVYGNEKEVGEAIT 223 +T N+G IP GTWK P EVT V AID+G+ HID A VY NE+EVG+A Sbjct: 6 ITLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEVGQA-- 62 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 IKE ++R L++T+K W+ R ++ E+L+ L ++YLDLYLIH PQ K Sbjct: 63 --IKESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQVTKG-- 116 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS------------------NF 529 D WK +E L KEG KSIGVS +F Sbjct: 117 ----------------DIKGAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSDVWDSF 160 Query: 530 NSKQLERLLQHATVKPVVNQVECHPYL 610 N +QL+ LL HATVKPVVNQ+ HPY+ Sbjct: 161 NKEQLQELLAHATVKPVVNQILLHPYV 187 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 118 bits (285), Expect = 9e-26 Identities = 72/200 (36%), Positives = 112/200 (56%), Gaps = 2/200 (1%) Frame = +2 Query: 35 MAPKIPVVTFNNGETI-PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 211 M+ +P V +G+ + P G GTW+ + G V+ A++IGYRHID A +YGNE++VG Sbjct: 1 MSKLVPAV--RSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVG 58 Query: 212 EAITSKIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 388 A I+ V R+++F+T+K+W + F DL R A +++L+ L V +DL L+HWP+ Sbjct: 59 AA----IRNSGVKRDEIFLTTKVWIDQFADGDLQRSA-EKSLEKLGVDQVDLLLLHWPK- 112 Query: 389 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 +V +T KA+ + +G ++IG+SNF S QLE + + Sbjct: 113 ------------------PEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSE 154 Query: 569 VKPVVNQVECHPYLNQKRLK 628 +QVE HPYL+ K LK Sbjct: 155 APIATDQVEYHPYLSLKTLK 174 >UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 282 Score = 118 bits (285), Expect = 9e-26 Identities = 70/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 +T NNG TIP GLGT+ +P + AV A+D Y ID A VY NE+ VG + + K Sbjct: 4 ITLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK 63 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 R+++F+ +KLW +F A++ETL+ L Y+DL ++H P Sbjct: 64 ----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG--------- 107 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 D V ++ +E KEG +++IG+SNF+ Q +R+L V P +NQVE Sbjct: 108 ------------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVE 155 Query: 596 CHPYLNQKRLK 628 CHPY Q LK Sbjct: 156 CHPYFPQTELK 166 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 118 bits (283), Expect = 2e-25 Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 8/174 (4%) Frame = +2 Query: 47 IPVVTFNNG----ETIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205 +P + +G ++PV G GT S +P + + V +AI +GYRH D + Y E+ Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEP 65 Query: 206 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382 +GEA+ + G+V +R + F+T+KLW LV A++ +L NL + YLDLY+IHWP Sbjct: 66 IGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWP 125 Query: 383 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544 + K FP D+ F +D+ W ME + GL K IGVSNF+ K+L Sbjct: 126 VSSKPGKYKFPIDED---DFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 117 bits (282), Expect = 2e-25 Identities = 70/187 (37%), Positives = 101/187 (54%), Gaps = 2/187 (1%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 IPV GLGTW+S + V + +GY HID A YGNE EVG+ IK+ V R+ Sbjct: 16 IPVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKG----IKQSGVARDK 71 Query: 260 LFITSKLW--NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 433 F+T+K++ + P+ + A + +L+NL+ Y+DL L+HWP Sbjct: 72 FFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD---------------- 115 Query: 434 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 613 V +T A+ L K+GL ++IGVSNFN + ++A V VVNQVE HP++ Sbjct: 116 ---DRVPLSETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPFIK 172 Query: 614 QKRLKEF 634 QK L+ F Sbjct: 173 QKTLQTF 179 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 117 bits (281), Expect = 3e-25 Identities = 68/188 (36%), Positives = 103/188 (54%) Frame = +2 Query: 71 GETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250 G ++P GLGTW+ + V+ A+ +GYRHID A YGNE++VG + + V Sbjct: 8 GTSVPALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA----AAVD 63 Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430 RED+F+T+KL + VR + +E+L+ L YLDL LIHWP T Sbjct: 64 REDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWPN----------TPWMA 113 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610 + +T AM +V+EGLV+ IGVSNF+ L+R ++ +QV+ HPY Sbjct: 114 SLS-------ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYW 166 Query: 611 NQKRLKEF 634 +Q++L ++ Sbjct: 167 DQRKLLDY 174 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 117 bits (281), Expect = 3e-25 Identities = 72/198 (36%), Positives = 100/198 (50%) Frame = +2 Query: 41 PKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 220 P IP ++ N+G GLGT+ + E A+ AID GYR +D A Y NE EVG A Sbjct: 2 PNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA- 60 Query: 221 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 400 ++ V R++L + SK+ H +++ +LD L + +DL LIHW Sbjct: 61 ---VRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHW------- 110 Query: 401 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 580 P G+ ++DTW+ M + GLV+SIGVSNF L+ L+ V P Sbjct: 111 ----PNPSVGR-------WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPA 159 Query: 581 VNQVECHPYLNQKRLKEF 634 VNQVE HPY Q L+ F Sbjct: 160 VNQVELHPYFPQAALRAF 177 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 116 bits (280), Expect = 4e-25 Identities = 63/188 (33%), Positives = 101/188 (53%), Gaps = 1/188 (0%) Frame = +2 Query: 74 ETIPVFGLGTWKSKPGEV-TQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250 + +P+ G+GT++ + V T + +A +GYR ID A +Y NE +G + +++ + Sbjct: 14 DRMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLK 73 Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430 RED+FITSK+ ++ ++L +L Y+DL LIHWP S ++ Sbjct: 74 REDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGT-----SRLKSNHKD 128 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610 +F YV+ +E L+ EG ++SIGVSN+ K LE LL + P +NQ ECHP+ Sbjct: 129 NAKFRAETYVE----LETLMDEGKIRSIGVSNYEIKHLETLLAECRILPAINQCECHPHF 184 Query: 611 NQKRLKEF 634 L E+ Sbjct: 185 RNSELAEY 192 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 116 bits (278), Expect = 6e-25 Identities = 70/194 (36%), Positives = 102/194 (52%), Gaps = 1/194 (0%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 P V NN +P+ GLGT++ + E T AV A+ GYR D A VY NE +G A+ Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 + + ++RED+FITSKL + R Q++L+ L + Y+DLYLIHWP Sbjct: 66 LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQG---- 120 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 P + + +W+ +E EG ++IGVSN+ + ++ LL+ V P V Sbjct: 121 -LPVGDKRNPE----NRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVL 175 Query: 587 QVECHPYLNQKRLK 628 QVE HP L Q L+ Sbjct: 176 QVEFHPKLLQNDLR 189 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 116 bits (278), Expect = 6e-25 Identities = 68/195 (34%), Positives = 105/195 (53%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P V + G +P+ G+GTW K E AV AI+ GYR +D A YGNE+ VG+A Sbjct: 9 PTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKA---- 64 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 ++E R ++F+T+K +H V AL+ +L+ L + Y+DL+L+HWP +GS Sbjct: 65 VREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM--PGEGS- 121 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 YVD ++ M L ++GL K+IGVSNF L+ L+ + P VNQ Sbjct: 122 ---------------YVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQ 165 Query: 590 VECHPYLNQKRLKEF 634 ++ P + +++F Sbjct: 166 IQLDPSRPRLEVRDF 180 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 116 bits (278), Expect = 6e-25 Identities = 72/193 (37%), Positives = 103/193 (53%), Gaps = 8/193 (4%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI--KEGV--- 244 +P+ G+GT+K ++ +K ++ GYR ID A +Y NE+ +G+ + + +G+ Sbjct: 27 MPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGK 84 Query: 245 -VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 + REDLFITSK + A + +L L + YLD YLIHWP DGS D Sbjct: 85 KIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGS----D 140 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ--HATVKPVVNQVE 595 IQ TW+A+E L ++ V+SIGVSN+ L LL + +KP +NQVE Sbjct: 141 SGNSIQ-----RAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVE 195 Query: 596 CHPYLNQKRLKEF 634 HP QK L EF Sbjct: 196 FHPLNFQKDLLEF 208 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 116 bits (278), Expect = 6e-25 Identities = 75/198 (37%), Positives = 103/198 (52%), Gaps = 8/198 (4%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGT---WKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEK 202 +P V +NG IP G G+ WK PGE + AV AI+ G+ HID A YG EK Sbjct: 3 VPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEK 62 Query: 203 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 382 ++GEA IKE V R+D+F+TSK D + ++ L L Y DL+LIH P Sbjct: 63 QIGEA----IKESGVPRKDIFLTSKTLFGLLADDPIE-SISNQLKTLQTDYFDLFLIHVP 117 Query: 383 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 562 P D + D W +E L ++GL K+IGVSN + +LE +++ Sbjct: 118 ----------PNDD------INYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKV 161 Query: 563 ATVKPVVNQVECHPYLNQ 616 A +KP VNQ+E HP L + Sbjct: 162 AKIKPHVNQIEFHPLLQE 179 >UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 253 Score = 116 bits (278), Expect = 6e-25 Identities = 73/199 (36%), Positives = 98/199 (49%), Gaps = 7/199 (3%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P + N+G +P G G WK V +AI GYR D A Sbjct: 4 PTLKLNSGHEMPQVGFGLWKVDNATCADTVYNAIKTGYRLFDGAC--------------- 48 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDG 403 DLFI SKLWN+FH D V ++ L + + Y DL+++H+P A Y + Sbjct: 49 ---------DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVALRYVDPA 99 Query: 404 SLFP-----TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 568 +P +D+ G +Q S +TW+AME LV EGL KSIGVSNF L LL++A Sbjct: 100 VRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGVSNFQGALLIDLLRYAR 159 Query: 569 VKPVVNQVECHPYLNQKRL 625 ++P Q+E HPYL Q L Sbjct: 160 IRPATLQIEHHPYLVQNTL 178 >UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo sapiens (Human) Length = 188 Score = 70.9 bits (166), Expect(2) = 8e-25 Identities = 34/68 (50%), Positives = 47/68 (69%) Frame = +2 Query: 146 AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQ 325 AI+ G+ HID A+VY NE++VG I +G V RED+F TSKLW+ HRP+LVR AL+ Sbjct: 2 AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55 Query: 326 ETLDNLNV 349 D +++ Sbjct: 56 ILFDTVDL 63 Score = 65.7 bits (153), Expect(2) = 8e-25 Identities = 36/70 (51%), Positives = 44/70 (62%), Gaps = 2/70 (2%) Frame = +2 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHP 604 +I F VD TW+AME KSIGVSNFN + LE +L +K PV NQVECHP Sbjct: 55 EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHP 106 Query: 605 YLNQKRLKEF 634 Y NQ++L +F Sbjct: 107 YFNQRKLLDF 116 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 115 bits (277), Expect = 8e-25 Identities = 65/191 (34%), Positives = 104/191 (54%), Gaps = 1/191 (0%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N+G IP G GT+K V A+ A+ GYR D A Y NEKE+GEA+ + + Sbjct: 16 NSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKHG 75 Query: 245 VTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 421 ++R D+F+TSK + + + + RG ++E+L +L Y+D+YL+H+P+ D D Sbjct: 76 LSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSD-----ND 130 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 601 ++ + Y + +E G V+SIGVSN+ LE L +A V P NQ+E H Sbjct: 131 DVNNAEYRKIAY----EVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYH 186 Query: 602 PYLNQKRLKEF 634 P+ + L+++ Sbjct: 187 PHFARIPLQKY 197 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 115 bits (276), Expect = 1e-24 Identities = 69/180 (38%), Positives = 98/180 (54%), Gaps = 1/180 (0%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 NG +P+ GLG +K++ + AID GYR ID A VY NE+ VG AI K+ Sbjct: 8 NGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAI----KQTK 63 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + RED+FIT+K+W + + + ++ ++L L Y+DL L+H P Sbjct: 64 IKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG------------ 111 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 DY WKA+E L K+G+VK+IGVSNF + +L H VKPV+NQ+E HP Sbjct: 112 ---------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHP 162 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 115 bits (276), Expect = 1e-24 Identities = 70/191 (36%), Positives = 98/191 (51%), Gaps = 4/191 (2%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T NNG +P G G ++ E QAV DAI+ GYR ID A VYGNE E G+ + I Sbjct: 5 TLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIAN 64 Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 VV RE+LF+T+KLW + + +GA+ ++L L Y DL L+H P Sbjct: 65 AVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG---------- 114 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF-NSKQLERLLQHATVK---PVVN 586 D +KA+ +G VKSIG+SNF +K +E + T+ P ++ Sbjct: 115 -----------DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQID 163 Query: 587 QVECHPYLNQK 619 Q+E HPY +K Sbjct: 164 QIEFHPYYQEK 174 >UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus scrofa (Pig) Length = 206 Score = 105 bits (252), Expect(2) = 1e-24 Identities = 63/127 (49%), Positives = 72/127 (56%), Gaps = 1/127 (0%) Frame = +2 Query: 80 IPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256 IPV GLGTW++ PG EVT+AVK AID GYRH D AY+Y NE EVG I +KI EGVV RE Sbjct: 2 IPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRRE 61 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436 DLFI SK YLDL IHWP +K P D+SG I Sbjct: 62 DLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGMI 99 Query: 437 QFSDVDY 457 S+ D+ Sbjct: 100 VASNTDF 106 Score = 30.3 bits (65), Expect(2) = 1e-24 Identities = 11/15 (73%), Positives = 12/15 (80%) Frame = +2 Query: 575 PVVNQVECHPYLNQK 619 PV NQ+E HPYL QK Sbjct: 109 PVTNQIESHPYLTQK 123 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 114 bits (275), Expect = 1e-24 Identities = 69/193 (35%), Positives = 99/193 (51%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 + N+G +P G G W +V ++ A+ G+RH D A Y NE VG A ++ Sbjct: 6 ILLNDGYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRA----LR 61 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 V RE LFITSK+ + ETL+ L V+YL+L+LIHWP K Sbjct: 62 YTEVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKN------ 115 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 YV+TW+A L GL++SIGVSNF + +ERL++ V P VNQ+E Sbjct: 116 ------------LYVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLE 163 Query: 596 CHPYLNQKRLKEF 634 HP+ Q ++++ Sbjct: 164 LHPHFQQCDVRDY 176 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 114 bits (275), Expect = 1e-24 Identities = 68/211 (32%), Positives = 109/211 (51%) Frame = +2 Query: 2 SSQAAAKIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCA 181 ++ +A +I K V NNG +P+ G+G W P + ++V +A+ GYR ID A Sbjct: 27 AADSAGQIFHPFDFKKRTVKLNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLIDTA 86 Query: 182 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLD 361 +Y NE+ VG A +++ + RE++FIT+K++ + + A+ E L L+ Y+D Sbjct: 87 RMYRNEQAVGRA----VRDSGIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYID 141 Query: 362 LYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQ 541 L L+H+P D + WK ME VK G +++IG+SN++ K Sbjct: 142 LLLLHYP---------------------DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKT 180 Query: 542 LERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 R++Q AT+ P V Q E H Y K+ K F Sbjct: 181 FNRIMQAATITPAVVQNEVHIYNQDKQTKAF 211 >UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 287 Score = 114 bits (275), Expect = 1e-24 Identities = 72/191 (37%), Positives = 98/191 (51%) Frame = +2 Query: 38 APKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 217 A IP + +G TIP GLGTW E AV+ A+ GYR +D A+ Y NE+ VG Sbjct: 10 ASDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRG 69 Query: 218 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 397 I+ V R +LFI+SK H D V+ A E+L L + +LD+++ HW Sbjct: 70 ----IRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW------ 119 Query: 398 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 577 P GK YVD WK + L++EG VK+IGVSNF L+ ++ V P Sbjct: 120 -----PVPALGK-------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVP 167 Query: 578 VVNQVECHPYL 610 VNQ++ P L Sbjct: 168 DVNQIQLSPDL 178 >UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 272 Score = 114 bits (274), Expect = 2e-24 Identities = 65/187 (34%), Positives = 100/187 (53%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 247 NG IP GLGTW+ + V+ A+ +GYRHID A VY NE+EVG+ ++ V Sbjct: 7 NGARIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDG----VRASGV 62 Query: 248 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 427 R+D+F+T+K+W P+ + +++E+L L + +DL L+HWP Sbjct: 63 RRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPN-------------- 108 Query: 428 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 607 S V +T A+ + GL + IGVSNF +E+ + + V NQVE HPY Sbjct: 109 -----SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPY 163 Query: 608 LNQKRLK 628 L+Q +++ Sbjct: 164 LDQAKVR 170 >UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 293 Score = 113 bits (272), Expect = 3e-24 Identities = 72/194 (37%), Positives = 107/194 (55%), Gaps = 3/194 (1%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKI 232 +T +G +P FG+G W + E QA+ +A D GYRH+D A Y NE + GEA + Sbjct: 19 ITMVDGYAMPRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEADCGEA----V 74 Query: 233 KEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 +E V R +LF T+K++ N R A++++L + YLDL L+H P DG Sbjct: 75 RECSVPRSELFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP-----DG-- 127 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL-QHATVKPVVN 586 GK +F +D+W + LV+EG V+S+GVSNF ++ L+ V PV N Sbjct: 128 ------GK-KFR----LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCN 176 Query: 587 QVECHPYLNQKRLK 628 Q+ECHP+ QK ++ Sbjct: 177 QIECHPFFAQKEVR 190 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 113 bits (271), Expect = 4e-24 Identities = 54/105 (51%), Positives = 68/105 (64%) Frame = +2 Query: 59 TFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 T +G +P+ G GTWK+ E QAV A+ GYRHIDCA VY NE VG AI+ I Sbjct: 7 TLQSGAKMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAISG 66 Query: 239 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLI 373 GVV REDLFITSK+WNT H D V + +++L + V Y DL+L+ Sbjct: 67 GVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111 Score = 41.5 bits (93), Expect = 0.016 Identities = 19/44 (43%), Positives = 28/44 (63%) Frame = +2 Query: 500 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 631 LV+ IGVSN++ L L +A +KP VNQ E H Y + +L++ Sbjct: 110 LVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRD 153 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 112 bits (270), Expect = 6e-24 Identities = 65/192 (33%), Positives = 105/192 (54%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 +T NNG +P+ GLGT+ +A+ +AI++GYR D A +Y NE E+G AI + +K Sbjct: 4 LTLNNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVK 63 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 G + RE+ FI +KL + DL + +++++L L + Y+D LIH P Y + +++ Sbjct: 64 GG-IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMY- 118 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 +AME K+G+++ IG+SNF +K ++ V P +NQ E Sbjct: 119 ------------------RAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCE 160 Query: 596 CHPYLNQKRLKE 631 H L QK L+E Sbjct: 161 THLLLQQKPLRE 172 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 112 bits (270), Expect = 6e-24 Identities = 74/190 (38%), Positives = 100/190 (52%), Gaps = 1/190 (0%) Frame = +2 Query: 68 NGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 +G +PV G GT+ + + A++ A D GYR D A +Y NE +G AI ++ Sbjct: 14 DGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAI----QQLG 69 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 + RE LF+TSK+ D A++ +L L YLDL LIHWP +E Sbjct: 70 LPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWP--VREH-------- 119 Query: 425 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 604 + DTW+A+E L +G VKSIGVSN+ LE L A PVVNQVE HP Sbjct: 120 ----------FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHP 169 Query: 605 YLNQKRLKEF 634 YLNQ+ L ++ Sbjct: 170 YLNQQALADY 179 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 112 bits (270), Expect = 6e-24 Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 1/204 (0%) Frame = +2 Query: 26 ISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 205 +S+ + VT NG IP G G + K E V A+D GYRHID A VYGNE Sbjct: 1 MSESQTESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDI 60 Query: 206 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 G+AI ++ V R D+F+TSKL N R A++ +L +L Y+DL+LI P Sbjct: 61 CGKAIVDWCEKNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLGT-YIDLFLIQSPA 118 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQH 562 K+ + +WKAME V G ++S+GVSN+ K L+ L + Sbjct: 119 GGKK------------------SRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASN 160 Query: 563 ATVKPVVNQVECHPYLNQKRLKEF 634 P VNQ+E HP+L+Q + ++ Sbjct: 161 PKFYPCVNQIELHPFLSQDDIVKY 184 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 112 bits (269), Expect = 8e-24 Identities = 73/192 (38%), Positives = 98/192 (51%), Gaps = 1/192 (0%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 IP + N+G IP G G ++ S E +AV+ AI GYR ID A Y N+ VGEAI Sbjct: 4 IPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGEAI- 62 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 K V R+D+F+T+KLW + + A+ E L L Y+D+ L+H QAY Sbjct: 63 ---KNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAYG--- 114 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 D W+A+E K G KSIGVSNF QL L + VKPVV Sbjct: 115 ----------------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVV 158 Query: 584 NQVECHPYLNQK 619 NQ+E +P+ ++ Sbjct: 159 NQIEVNPWFQRE 170 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 111 bits (268), Expect = 1e-23 Identities = 64/203 (31%), Positives = 100/203 (49%), Gaps = 18/203 (8%) Frame = +2 Query: 80 IPVFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250 +P G G + + G + ++ A+D GYR +D A +YGNE +G + + G Sbjct: 378 LPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GAPD 434 Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL------- 409 R +FI K+W T HR + A + +LD L + D Y +HWP+A GSL Sbjct: 435 RRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKS 494 Query: 410 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 FP + G I+ V W+ +E L + G +++G+ N + QLE +++ Sbjct: 495 VARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETG 554 Query: 566 TVKPVVNQVECHPYLNQKRLKEF 634 TV+P + QVE HPY Q L E+ Sbjct: 555 TVRPALVQVERHPYQPQTDLIEY 577 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 111 bits (266), Expect = 2e-23 Identities = 65/196 (33%), Positives = 95/196 (48%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 +P + +G +IP GLG + V V+ A++ GYRHID A Y NE VG A+ + Sbjct: 11 VPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAA 70 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 RE L++T+KL ++ D A +L L + Y+D+Y+IHWP + Sbjct: 71 SGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF----- 125 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 D DTWKA L EG+ +++GV NF L+RL + P VN Sbjct: 126 -------------DWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVN 172 Query: 587 QVECHPYLNQKRLKEF 634 Q+E HP Q+ + F Sbjct: 173 QIELHPTWQQREVVAF 188 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 111 bits (266), Expect = 2e-23 Identities = 69/186 (37%), Positives = 97/186 (52%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P VT NG +P GLGTW E +AV AI+ GYR ID A Y NE VG+ Sbjct: 8 PTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQG---- 63 Query: 230 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 409 I++ V R+++F+T+K+ +H D R A + +L+ L + Y+DL+LIHWP Sbjct: 64 IRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN-------- 115 Query: 410 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 DQ YV+ ++ + L+ GLV++IG SNF L L V P VNQ Sbjct: 116 --PDQG--------TYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQ 164 Query: 590 VECHPY 607 ++ PY Sbjct: 165 IQLDPY 170 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 110 bits (265), Expect = 2e-23 Identities = 67/187 (35%), Positives = 100/187 (53%), Gaps = 1/187 (0%) Frame = +2 Query: 77 TIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256 T+P FGLGT++ K V +V++A+ +GYR ID A +Y NE +VG+AI + V R+ Sbjct: 2 TVPAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRD 57 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436 LF+T+K+W D ++ +LQE+L L Y+DL LIHWP P DQ Sbjct: 58 QLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWPS---------PKDQ---- 104 Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV-VNQVECHPYLN 613 V + +A+ +GL ++IGVSNF + ++ + NQ+E HPYL Sbjct: 105 ----VPMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQ 160 Query: 614 QKRLKEF 634 + L F Sbjct: 161 NRTLIAF 167 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 110 bits (265), Expect = 2e-23 Identities = 67/193 (34%), Positives = 108/193 (55%), Gaps = 3/193 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N+ IP G G ++S G+ Q+ A++ GYRHID A YGNEKEVGEA +++ Sbjct: 15 NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEA----LRKCG 70 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQ--YLDLYLIHWPQAYKEDGSLFPT 418 + R D+F+T+K+ + P+ L E+++ + + Y+DL+LIH + Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------------S 117 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVE 595 SG ++ W+A+E L++EG +SIGVSNF K +E + +A V P VNQ+E Sbjct: 118 SSSGSAGRKEL-----WQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIE 172 Query: 596 CHPYLNQKRLKEF 634 HP+ Q+ ++ + Sbjct: 173 LHPWCQQRVIEAY 185 >UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 292 Score = 110 bits (264), Expect = 3e-23 Identities = 71/200 (35%), Positives = 106/200 (53%), Gaps = 9/200 (4%) Frame = +2 Query: 44 KIPVVTFNNGETIPVFGLGT----WKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGN 196 K P ++ +G +P+ G GT +K P + T + +K A++ G+ HID A YG Sbjct: 2 KWPALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGT 61 Query: 197 EKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIH 376 E+EVG A I+E + RE LFIT+K+ + V GAL +L+ L + Y+DLYL+H Sbjct: 62 EREVGIA----IRESGIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLH 114 Query: 377 WPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 556 P + P +D+ WK +E + G +SIGVSNF LE +L Sbjct: 115 NPY-------VIP-------NLTDIQ--SAWKGLEAVKATGKARSIGVSNFQRNHLEAIL 158 Query: 557 QHATVKPVVNQVECHPYLNQ 616 + +V P +NQ+E HPYL + Sbjct: 159 ETCSVVPAINQLEYHPYLQR 178 >UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans Length = 321 Score = 110 bits (264), Expect = 3e-23 Identities = 74/197 (37%), Positives = 106/197 (53%), Gaps = 1/197 (0%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAIT 223 IP +N +P+ GLGT S G AV +I GYR ID A YG EK++G A+ Sbjct: 2 IPTTVLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAV- 59 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 K V RE++F+++KLW D V A Q + + L YLD+Y+IH PQ D Sbjct: 60 ---KNCSVPREEMFLSTKLWPV-DCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQL--PDW 113 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 + + K TW+ ME L ++ V+SIGVSN++ + L+ LL+ A++ P Sbjct: 114 IVNQKETKEK----------TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163 Query: 584 NQVECHPYLNQKRLKEF 634 NQVE HP+ +Q LK + Sbjct: 164 NQVELHPWFHQADLKNY 180 >UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 186 Score = 109 bits (262), Expect = 5e-23 Identities = 72/174 (41%), Positives = 93/174 (53%), Gaps = 1/174 (0%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N G IP GLGTWKS+PGEV +A+ A+ GYRHID A +G Sbjct: 10 NPGALIPAVGLGTWKSEPGEVARALAHALKTGYRHIDAA--------LG----------- 50 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 424 V RE++FITSKLWNT H+P++ G LQ+TLD L V LDLY E L P + Sbjct: 51 VPREEIFITSKLWNT-HQPNIKEG-LQKTLDALGVDCLDLY--------NETSDLLPVNP 100 Query: 425 SG-KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 G + D +TW+ ME K G K+IGV+N++ LE LL + +V Sbjct: 101 DGTRAVDRSWDQSETWRQMEDFYKSGKAKAIGVANWSIPYLEELLADEVTRAIV 154 >UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 212 Score = 109 bits (261), Expect = 7e-23 Identities = 69/179 (38%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +2 Query: 65 NNGETIPVFGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 + G+ IP+ G+ T + P E + ++ AI++GYRH DC Y +EK +GEAI +K Sbjct: 5 STGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVK 64 Query: 236 EGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 G++ +R++LFIT + AL NL + YLDLYLIHW + K Sbjct: 65 LGLIKSRDELFITLQ-------------AL-----NLQLDYLDLYLIHWSVSLKPGNYEL 106 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 589 P ++ + +D WKAME K L K+IGVSNF+ +LE LLQ A++ P VNQ Sbjct: 107 PVNKDDHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQ 162 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 108 bits (260), Expect = 9e-23 Identities = 70/190 (36%), Positives = 98/190 (51%), Gaps = 1/190 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 V NNG +P+ G GT++ + GE QAVK+AI GYRHID A Y NE+ VG I + Sbjct: 4 VKLNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA-- 61 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 V R++LFIT+K+W V + +L L + Y+DL LIH P Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP---------- 109 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 ++DV W AME L +G +K+IGVSNF ++ L + P VNQ+ Sbjct: 110 ---------YNDV--YGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQI 158 Query: 593 ECHPYLNQKR 622 E +P+ Q + Sbjct: 159 EINPFQQQSK 168 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 108 bits (260), Expect = 9e-23 Identities = 67/184 (36%), Positives = 98/184 (53%), Gaps = 1/184 (0%) Frame = +2 Query: 77 TIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256 TIP G GT++ K + AV++A+D+GYRHID A Y NE EVG+AI++ ++R Sbjct: 10 TIPTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRG 65 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436 +LF+T+K+W D ++Q +L LN Y+DL L+HWP S Sbjct: 66 ELFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP--------------SPDN 111 Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV-NQVECHPYLN 613 + S +Y+ KA + + GL + IGVSNF QL+ L ++ NQ+E HP Sbjct: 112 KVSMAEYLKELKACK---ERGLTRHIGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQ 168 Query: 614 QKRL 625 K L Sbjct: 169 NKEL 172 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 108 bits (259), Expect = 1e-22 Identities = 71/209 (33%), Positives = 104/209 (49%), Gaps = 6/209 (2%) Frame = +2 Query: 23 IISKMAPKIPV------VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAY 184 I+S+M+ PV + ++G IP FGLG ++ E VK A++ GYRH+D A Sbjct: 16 ILSEMSGPAPVKSLDARLKMHDGNAIPQFGLGVYEMNDKETYDCVKWALEAGYRHVDTAE 75 Query: 185 VYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 364 Y NE G+AI +K +RE++F+TSKL N L+ +L V+Y DL Sbjct: 76 WYENEAPCGKAIADFLKATGTSREEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDL 134 Query: 365 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 544 YL+H + G + +V WKA+ +GLVKSIGVSNF K + Sbjct: 135 YLMH-------------SAIGGPVIRKNV-----WKALCDAQSQGLVKSIGVSNFGKKHI 176 Query: 545 ERLLQHATVKPVVNQVECHPYLNQKRLKE 631 + + P VNQV+ HP++ + E Sbjct: 177 QEFIDQKVPLPTVNQVDLHPFMRHPEIVE 205 >UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2; Ostreococcus|Rep: Aldo/keto reductase family proteins - Ostreococcus tauri Length = 336 Score = 107 bits (257), Expect = 2e-22 Identities = 66/188 (35%), Positives = 100/188 (53%) Frame = +2 Query: 71 GETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250 G T+P+ GT++ + AV+DA+ G++H+D A VYGNE++VGEA+ + +E Sbjct: 59 GITMPMLAFGTYRLRGETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACHRE---V 115 Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430 E +F+TSK+ + R + A ++ + DL L+HWP KE P + Sbjct: 116 SERIFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTPDLVLVHWPGRDKES----PDSE-- 169 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610 + D TW+A+E +K G ++IGVSN+ L LLQ VKP VNQ+E H Sbjct: 170 --RHRDARRW-TWRALENALKMGQCRAIGVSNYELSHLRELLQFCDVKPAVNQIELHARF 226 Query: 611 NQKRLKEF 634 Q L+ F Sbjct: 227 PQTELRAF 234 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 106 bits (255), Expect = 4e-22 Identities = 67/193 (34%), Positives = 105/193 (54%), Gaps = 4/193 (2%) Frame = +2 Query: 68 NGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI-KEGV 244 NG IP G+G + + V+ A+D+GYR ID A Y NE+E GE I + + K+ Sbjct: 14 NGSRIPACGVGVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKDKN 73 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNL-NVQYLDLYLIHWPQAYKEDGSLFPTD 421 RED+ T+K+ N D +L+E+L+ + +++Y+DL LIH P + K+ Sbjct: 74 NKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLSDKK-------- 125 Query: 422 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVE 595 ++TWKA++ V G+VKSIGVSNF ++ L + KP+VNQ+E Sbjct: 126 ----------TRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175 Query: 596 CHPYLNQKRLKEF 634 P+L +K L ++ Sbjct: 176 LSPWLMRKDLVDY 188 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 106 bits (254), Expect = 5e-22 Identities = 68/177 (38%), Positives = 91/177 (51%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 IP GLGTW + T+AV I+ GYR ID A +Y NE VG A+ E V RE+ Sbjct: 4 IPPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREE 59 Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439 LF+T+KL + H +RGA++ +L NL + LDL+LIHWP P Sbjct: 60 LFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWP---------LPRHNR---- 106 Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610 YV ++AM GLV+ +GVSNF L R++ P VNQ++ P L Sbjct: 107 -----YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSL 158 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 105 bits (253), Expect = 7e-22 Identities = 61/202 (30%), Positives = 96/202 (47%), Gaps = 18/202 (8%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKD---AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250 +P G G + + GE V A+D GYR +D A +YGNE +GE + + G Sbjct: 376 LPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GAPD 432 Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL------- 409 RE +F+ K W T HR + + A + + L + D Y +HWP A + G L Sbjct: 433 RERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAEKP 492 Query: 410 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 FP + G+ +DV W+ +E + + G +++G+ N + QLE +L+ Sbjct: 493 VERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGICNVSRAQLETVLETG 552 Query: 566 TVKPVVNQVECHPYLNQKRLKE 631 + P + QVE HPY + L E Sbjct: 553 EIDPALVQVERHPYRPRNGLVE 574 >UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 279 Score = 105 bits (251), Expect = 1e-21 Identities = 62/185 (33%), Positives = 92/185 (49%), Gaps = 1/185 (0%) Frame = +2 Query: 80 IPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 256 +P+ GLGTW+++ E ++V+ A++ GYRHID A Y NE VG+ I + V R+ Sbjct: 17 MPMLGLGTWQNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA----ADVDRD 72 Query: 257 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 436 D+F+ +K+W + D V +E+LD L V +DL +HW E P Sbjct: 73 DIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP------- 125 Query: 437 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616 A + LV GL+ ++GVSNF +E + NQVE HP+L Q Sbjct: 126 ------------AFDELVDRGLIDNVGVSNFEPHHVETAMDVLDAPVFANQVETHPFLQQ 173 Query: 617 KRLKE 631 L+E Sbjct: 174 SELRE 178 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 104 bits (250), Expect = 2e-21 Identities = 70/188 (37%), Positives = 95/188 (50%), Gaps = 1/188 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 232 V NNG +P+ G GT++ + E AVKDAI GYRHID A Y NE+ VG I + Sbjct: 4 VKLNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA-- 61 Query: 233 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 412 V R++LFIT+K+W V + +L L + Y+DL LIH P Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP---------- 109 Query: 413 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 592 F+DV W AME L G +++IGVSNF+ ++ L V P VNQ+ Sbjct: 110 ---------FNDV--YGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQI 158 Query: 593 ECHPYLNQ 616 E +P+ Q Sbjct: 159 EVNPFQQQ 166 >UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid reductase; n=5; Pezizomycotina|Rep: Related to 2, 5-diketo-D-gluconic acid reductase - Neurospora crassa Length = 289 Score = 104 bits (249), Expect = 2e-21 Identities = 66/196 (33%), Positives = 102/196 (52%), Gaps = 5/196 (2%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 V +NG +IP LG + E T+AV+ A+ GYR D A Y NE+E G+AI S + Sbjct: 13 VKLSNGLSIPQIQLGLYMMSGPETTRAVRWALGAGYRGFDSAQWYYNEREAGQAILSFLS 72 Query: 236 E----GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 +TR+D+ TSKL + D VR ++ +++ + Y+DL+L+H P +E Sbjct: 73 SPENTAGLTRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSPLGGRE-- 130 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPV 580 + +WKA+E V G VK GVSN+ K L+ ++ +KP+ Sbjct: 131 ----------------ARLTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPL 174 Query: 581 VNQVECHPYLNQKRLK 628 VNQ+ECHP+ Q ++ Sbjct: 175 VNQIECHPFNTQPEIR 190 >UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 302 Score = 104 bits (249), Expect = 2e-21 Identities = 66/192 (34%), Positives = 97/192 (50%), Gaps = 2/192 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N T+P G GT+++ + AVK+A+D GY HID A Y NE VG A I++ Sbjct: 15 NGTTTVPTLGFGTYRTGGYKCYNAVKNALDCGYTHIDTAMAYENEAAVGRA----IEQSS 70 Query: 245 VTREDLFITSKLWNTFHRPDLVR--GALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 418 V RED+F+T+K+ + R A + L+ L +YLDL L+HW Sbjct: 71 VDREDIFLTTKIKGYPEMVEYERLIEAAKGCLERLGTEYLDLLLVHWWNPL--------- 121 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 598 D +T+ A+ LV +GLV IGVSNF+ K+L++ ++ + NQ+E Sbjct: 122 ----------ADMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQIEY 171 Query: 599 HPYLNQKRLKEF 634 HPY + L F Sbjct: 172 HPYWGDEELVRF 183 >UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina baltica OS145|Rep: Aldo/keto reductase - Idiomarina baltica OS145 Length = 263 Score = 103 bits (248), Expect = 3e-21 Identities = 64/185 (34%), Positives = 95/185 (51%), Gaps = 1/185 (0%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 IP FG+GT++ + E+T V AID+GY HID A YGNE +VG+A+ T +D Sbjct: 2 IPQFGMGTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKD 55 Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439 +F+T+K+W V +LQ + D L +DL LIHWP P D Sbjct: 56 VFVTTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWPS---------PND------ 100 Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV-NQVECHPYLNQ 616 +V +T A++ ++GL+K +GVSNF L R H ++ NQ+E HP+ Sbjct: 101 --EVPVEETLDALQKAQQDGLIKHLGVSNFTIDLLNRAAAHVGKDEILTNQIEVHPFFQN 158 Query: 617 KRLKE 631 + + Sbjct: 159 HAITD 163 >UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 289 Score = 103 bits (248), Expect = 3e-21 Identities = 71/190 (37%), Positives = 96/190 (50%) Frame = +2 Query: 47 IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 226 IP++ +G IP+ LG G V K I+ G+ H+DCA +YG E+EV A Sbjct: 3 IPLLRLRDGNQIPL-DLGDTTFGQGLV-DLTKAVIEKGFYHLDCAEMYGTEEEVAIA--- 57 Query: 227 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 406 IKE V RE LFIT+K+ D + A+ ++L + Y DLYLIH P K Sbjct: 58 -IKESGVPREKLFITNKVAQGI---DDIEAAIDQSLQKMQTNYFDLYLIHIPFFAK---- 109 Query: 407 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 586 S+ D+ WK ME + K G +SIGVSN+ +E L+ AT PV N Sbjct: 110 ------------SEEDFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPPVTN 157 Query: 587 QVECHPYLNQ 616 Q+E H YL + Sbjct: 158 QIEYHAYLQR 167 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 103 bits (248), Expect = 3e-21 Identities = 62/194 (31%), Positives = 100/194 (51%), Gaps = 1/194 (0%) Frame = +2 Query: 56 VTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 235 V NNG P F G++ + +V A+ GYRHID A +Y NE + G AI ++ Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFME 65 Query: 236 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 E RED++ TSKL N ++ ++ + Y+DL+L+H P Sbjct: 66 ETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG--------- 115 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL-QHATVKPVVNQV 592 D +++WKA+E V+EG +++IGVSNF ++ LL H + P VNQ+ Sbjct: 116 ------------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQI 163 Query: 593 ECHPYLNQKRLKEF 634 E HP+ +Q+++ ++ Sbjct: 164 ELHPFCSQQKVVDY 177 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 103 bits (247), Expect = 4e-21 Identities = 76/201 (37%), Positives = 96/201 (47%), Gaps = 1/201 (0%) Frame = +2 Query: 35 MAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 214 M+ I N G +P GLGTW+S PG V QAV AI +GYRHIDCA VYGNE+E+G Sbjct: 1 MSDDIRFFQLNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGI 60 Query: 215 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 394 + +GVV REDL+ITSKLW T G ++ + P A Sbjct: 61 VLKKLFDDGVVKREDLWITSKLWCTESCTRRCTGGTKQNFEG-------------PAA-- 105 Query: 395 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQHATV 571 L P + F ++ TWK + ++ G +S L RL L A V Sbjct: 106 ---RLHPLANEYEKGFC---WLQTWKTS----PNQIYQAHGEQWKHSMILARLELLVARV 155 Query: 572 KPVVNQVECHPYLNQKRLKEF 634 P V QVECHP Q +L F Sbjct: 156 PPAVIQVECHPSWQQSKLHAF 176 >UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family; n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto reductase family - Mycoplasma penetrans Length = 299 Score = 103 bits (246), Expect = 5e-21 Identities = 65/194 (33%), Positives = 104/194 (53%), Gaps = 2/194 (1%) Frame = +2 Query: 50 PVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 229 P++T N+G IP+ GLGT A+K A++IG R D A +YGNEKEVGE Sbjct: 35 PLLTLNDGYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGET---- 90 Query: 230 IKEGVVTREDLFITSKLW--NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 I+E + R ++F+ +KL+ F P+ A++E L+ LN Y+D+ L+H P Sbjct: 91 IRESNINRNEIFVITKLYPGAQFANPE---KAIEEALNKLNTDYIDMMLLHHP------- 140 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 G+ + V +KA+E +++G +KS+G+SN+ K++ L +KP + Sbjct: 141 --------GE------NDVKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSL 186 Query: 584 NQVECHPYLNQKRL 625 Q E H Y +K + Sbjct: 187 IQNEIHIYYQEKEV 200 >UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 309 Score = 103 bits (246), Expect = 5e-21 Identities = 69/214 (32%), Positives = 107/214 (50%), Gaps = 4/214 (1%) Frame = +2 Query: 5 SQAAAKIISKMAPK---IPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHID 175 S+A I + P IP T +G+T+P GLGT+ ++ +V+ A+ GY HID Sbjct: 17 SEAVVSISEPLNPPRVTIPTQTLPSGDTLPALGLGTYALDDDQIADSVRAALSSGYTHID 76 Query: 176 CAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK-LWNTFHRPDLVRGALQETLDNLNVQ 352 A Y NE+ +GE + R+D+F+TSK L L++ + + +L+ L Sbjct: 77 TAEGYHNEEAIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQ-SCEASLERLETD 129 Query: 353 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 532 YLDLYLIHWP P + ++ +AM L GLV+++GVSNF+ Sbjct: 130 YLDLYLIHWPN---------PA----------ISLRESLQAMAELHDRGLVRNVGVSNFS 170 Query: 533 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 634 + QL + V VNQ+E HP+ + L ++ Sbjct: 171 AYQLSCANHISEVPIAVNQIEFHPWFQRPNLVDY 204 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 102 bits (245), Expect = 6e-21 Identities = 66/186 (35%), Positives = 100/186 (53%), Gaps = 1/186 (0%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 +P+ G GT++ K AV A++ G RHID A +YGNE+ VG+AI + + RE+ Sbjct: 17 MPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINT----SGIPREE 72 Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439 LFIT+K+W + ++ ++L L +YLDL LIHWP E Sbjct: 73 LFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEP------------- 119 Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV-VNQVECHPYLNQ 616 S V+Y+ KA ++ +GL + IGVSNF + QL + + + NQVE HPYL Sbjct: 120 -SMVEYLSELKA---VLDKGLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLIN 175 Query: 617 KRLKEF 634 +++ +F Sbjct: 176 RKVTDF 181 >UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus clavatus Length = 283 Score = 102 bits (245), Expect = 6e-21 Identities = 64/188 (34%), Positives = 101/188 (53%), Gaps = 3/188 (1%) Frame = +2 Query: 65 NNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 244 N+ IP G G ++S + Q+ A+ GYR+ID A Y NE+EVGEA ++ Sbjct: 15 NSSVRIPRLGFGVYRSPTRQCVQSCLTALQAGYRNIDTAQFYANEQEVGEA----LRTSG 70 Query: 245 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQ--YLDLYLIHWPQAYKEDGSLFPT 418 + R D+F+T+K+ + P+ L E+++ + + Y+DL+LIH + Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYKKLLESVEKIGGENGYVDLFLIH-------------S 117 Query: 419 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVE 595 SG ++ W+A+E L++EG KSIGVSNF K +E + +A V P VNQ+E Sbjct: 118 SSSGSAGRKEL-----WQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIE 172 Query: 596 CHPYLNQK 619 HP+ Q+ Sbjct: 173 LHPWCQQR 180 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 101 bits (243), Expect = 1e-20 Identities = 61/188 (32%), Positives = 94/188 (50%) Frame = +2 Query: 71 GETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 250 G +P GLGT++ + AV+ A+ +GYRHID A +Y NE +G A+ + + Sbjct: 8 GVRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQIA 63 Query: 251 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 430 REDL +T+K+W PD +R A +L L + ++DLYLIHWP G P Sbjct: 64 REDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPAT----GMNLPA---- 115 Query: 431 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 610 + + L +EG ++IGV+NF L++ ++ NQVE H L Sbjct: 116 -----------AMETLMALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVML 164 Query: 611 NQKRLKEF 634 +Q +L + Sbjct: 165 DQSKLMAY 172 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 101 bits (243), Expect = 1e-20 Identities = 73/209 (34%), Positives = 94/209 (44%), Gaps = 7/209 (3%) Frame = +2 Query: 2 SSQAAAKIISKMAPKIPVVTFNNGETIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCA 181 S+QA M T N TIP G GT+ + + AI GYRHID A Sbjct: 22 SNQANNGTEHPMTNTATTFTLNTTTTIPAVGFGTYLISNDDAKSTISAAIQAGYRHIDTA 81 Query: 182 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW--NTF--HRPDLVRGALQE---TLDN 340 Y NEK VG I + ++ +TR+DLF+T+KLW N P L E +L Sbjct: 82 SGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLAR 141 Query: 341 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 520 L + Y+DLYLIH P Y D L + W+A+ L G +SIGV Sbjct: 142 LGLDYVDLYLIHAP--YGGDMRL-----------------EQWRALLELQANGKARSIGV 182 Query: 521 SNFNSKQLERLLQHATVKPVVNQVECHPY 607 SNFN L + P NQ+E HP+ Sbjct: 183 SNFNESHLNEIKAAGLPMPDANQIELHPW 211 >UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismortui|Rep: Oxidoreductase - Haloarcula marismortui (Halobacterium marismortui) Length = 264 Score = 101 bits (241), Expect = 2e-20 Identities = 63/181 (34%), Positives = 95/181 (52%) Frame = +2 Query: 92 GLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFIT 271 G+GTW V ++V+ +++GY H+D A Y NE E+GEA+ RED+F+T Sbjct: 3 GVGTWDIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVFLT 56 Query: 272 SKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDV 451 SK+ + V A + +LD L YLDLYL+HWP + + I+ Sbjct: 57 SKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP------------NPATSIR---- 100 Query: 452 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 631 +T AM L +G ++++GVSNF++ QL A V VNQ+E HP+ Q ++ E Sbjct: 101 ---ETMNAMATLHDQGKIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVE 157 Query: 632 F 634 F Sbjct: 158 F 158 >UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 301 Score = 100 bits (239), Expect = 3e-20 Identities = 62/193 (32%), Positives = 105/193 (54%), Gaps = 2/193 (1%) Frame = +2 Query: 62 FNNGETIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 238 F++G +P GLG + + + + +++ A+ GYR D A +Y NE +G ++ + + Sbjct: 14 FSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLPQ 73 Query: 239 GVVTREDLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 415 +TRED+FIT+K+ + L +L L Y+DL LIH+P+ ++ G+ Sbjct: 74 FGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRD-RDTGN--- 129 Query: 416 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 595 D +I S V W+ +E + G V+SIGVSN+ L + ++A ++PV+NQ E Sbjct: 130 -DDDYEINKSRRKIV--WQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYE 186 Query: 596 CHPYLNQKRLKEF 634 PYL + LK+F Sbjct: 187 YQPYLTRPTLKKF 199 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 99.5 bits (237), Expect = 6e-20 Identities = 58/179 (32%), Positives = 90/179 (50%) Frame = +2 Query: 80 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 259 IP G GTW+ + + + + AI+ GYRHID A +Y NEK+VGE IK+ + R++ Sbjct: 11 IPRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEG----IKDSGIPRDE 66 Query: 260 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 439 LF+T+K+WN + A+ E+LD L + Y++L L+HWP Sbjct: 67 LFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWP------------------- 107 Query: 440 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 616 +D+ D + + + G K IG+SN+N Q + + Q E HP L+Q Sbjct: 108 INDMPIADQVGPLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQ 166 >UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 313 Score = 99.5 bits (237), Expect = 6e-20 Identities = 74/198 (37%), Positives = 100/198 (50%), Gaps = 13/198 (6%) Frame = +2 Query: 65 NNGETIP---VFGLGT-WKSKPG-------EVTQAVKDAIDI-GYRHIDCAYVYGNEKEV 208 NNG IP + G GT W +PG E+ + +K A+ + G HID A YG E+ Sbjct: 11 NNGNQIPSISIIGTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYPEL 70 Query: 209 GEAITSKIKEGVVTREDLFITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 385 +A+ KE R ++FIT K T D + G L L L + Y+DLYLIH P Sbjct: 71 AKAL----KESSKPRSEIFITDKYSTQTKFTNDPIEG-LNTGLKTLGLDYVDLYLIHSP- 124 Query: 386 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 565 F + G + V WK ME L KEG KSIGVSNF+ K +E +L+ A Sbjct: 125 -------FFDPEFKGSLTLEKV-----WKDMETLYKEGKAKSIGVSNFSVKNIEEILKIA 172 Query: 566 TVKPVVNQVECHPYLNQK 619 +KP VNQ+E + +L + Sbjct: 173 GIKPQVNQIEFNAFLQNQ 190 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 99.1 bits (236), Expect = 8e-20 Identities = 68/184 (36%), Positives = 93/184 (50%), Gaps = 9/184 (4%) Frame = +2 Query: 71 GETIPVFGLGTWK---------SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 223 GE IP GLGTW S+ E+ + +K AI +GY HID A YG E I Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGG-HTEELIG 68 Query: 224 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 403 IK+ REDLFI SK+W T R D + +L+ TL L+ Y+DLYLIHWP Sbjct: 69 KAIKD--FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWPN------ 120 Query: 404 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 583 ++ +T AM V++GL++ IGVSNF+ + LE + + V Sbjct: 121 -------------PEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVC 167 Query: 584 NQVE 595 +QV+ Sbjct: 168 DQVK 171 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 679,601,185 Number of Sequences: 1657284 Number of extensions: 15037284 Number of successful extensions: 64348 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 58145 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 63465 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 46881492319 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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