BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fmgV10n04f (659 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo... 178 1e-43 UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne... 158 1e-37 UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R... 153 3e-36 UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy... 147 2e-34 UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a... 142 7e-33 UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a... 142 9e-33 UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy... 141 1e-32 UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a... 140 4e-32 UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a... 137 3e-31 UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a... 132 7e-30 UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a... 132 7e-30 UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy... 130 2e-29 UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy... 129 7e-29 UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a... 127 3e-28 UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a... 126 4e-28 UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori... 125 1e-27 UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R... 124 1e-27 UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [... 122 6e-27 UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a... 121 2e-26 UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|... 120 2e-26 UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy... 120 3e-26 UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 120 3e-26 UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,... 114 2e-24 UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a... 107 3e-22 UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881... 106 5e-22 UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy... 103 5e-21 UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact... 101 2e-20 UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans... 98 1e-19 UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 96 6e-19 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 96 8e-19 UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor... 95 1e-18 UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 95 2e-18 UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 94 2e-18 UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim... 92 1e-17 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 91 2e-17 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 91 3e-17 UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb... 90 4e-17 UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 90 5e-17 UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 89 1e-16 UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 89 1e-16 UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:... 88 2e-16 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena... 87 3e-16 UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 87 4e-16 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 87 4e-16 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 87 5e-16 UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro... 85 1e-15 UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=... 85 1e-15 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb... 84 2e-15 UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re... 84 3e-15 UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 83 4e-15 UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr... 83 4e-15 UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 83 6e-15 UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re... 83 6e-15 UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil... 83 6e-15 UniRef50_Q28GY1 Cluster: Novel protein containing short chain de... 83 8e-15 UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 83 8e-15 UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 82 1e-14 UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel... 82 1e-14 UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 81 2e-14 UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 81 2e-14 UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 81 2e-14 UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei... 81 2e-14 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 81 2e-14 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 81 2e-14 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 81 2e-14 UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 81 3e-14 UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 81 3e-14 UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 81 3e-14 UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 80 4e-14 UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 80 4e-14 UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 80 5e-14 UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep... 80 5e-14 UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 79 7e-14 UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All... 79 9e-14 UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ... 79 9e-14 UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc... 79 9e-14 UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 79 9e-14 UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD... 79 9e-14 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 79 9e-14 UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena... 79 9e-14 UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 79 1e-13 UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 79 1e-13 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 79 1e-13 UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re... 79 1e-13 UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 79 1e-13 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 79 1e-13 UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb... 79 1e-13 UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 78 2e-13 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 78 2e-13 UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 78 2e-13 UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 78 2e-13 UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 78 2e-13 UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 78 2e-13 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 78 2e-13 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 3e-13 UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 77 3e-13 UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc... 77 4e-13 UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 77 4e-13 UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or... 77 4e-13 UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 77 5e-13 UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 77 5e-13 UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta... 77 5e-13 UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 77 5e-13 UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ... 77 5e-13 UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici... 77 5e-13 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 76 7e-13 UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 76 7e-13 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 76 7e-13 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 76 7e-13 UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR... 76 7e-13 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 76 7e-13 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 76 7e-13 UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 76 7e-13 UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR... 76 7e-13 UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam... 76 7e-13 UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote... 76 9e-13 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 76 9e-13 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 76 9e-13 UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR... 76 9e-13 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 76 9e-13 UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 75 1e-12 UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 75 1e-12 UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 75 1e-12 UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba... 75 1e-12 UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena... 75 1e-12 UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 75 1e-12 UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici... 75 1e-12 UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc... 75 1e-12 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 75 2e-12 UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro... 75 2e-12 UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 75 2e-12 UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu... 75 2e-12 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;... 75 2e-12 UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 75 2e-12 UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|... 75 2e-12 UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo... 74 3e-12 UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena... 74 3e-12 UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12 UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p... 74 4e-12 UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 74 4e-12 UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p... 74 4e-12 UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2... 74 4e-12 UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ... 74 4e-12 UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ... 74 4e-12 UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster... 74 4e-12 UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 74 4e-12 UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=... 73 5e-12 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 73 5e-12 UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 73 5e-12 UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 73 5e-12 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 73 5e-12 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 73 5e-12 UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 73 5e-12 UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 73 5e-12 UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 73 5e-12 UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000... 73 6e-12 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 73 6e-12 UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 73 6e-12 UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 73 6e-12 UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr... 73 6e-12 UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 73 6e-12 UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 73 6e-12 UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo... 73 6e-12 UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 73 8e-12 UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 73 8e-12 UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 73 8e-12 UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 73 8e-12 UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re... 73 8e-12 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 73 8e-12 UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 73 8e-12 UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a... 72 1e-11 UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 72 1e-11 UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2... 72 1e-11 UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:... 72 1e-11 UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:... 72 1e-11 UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11 UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena... 72 1e-11 UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 72 1e-11 UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo... 72 1e-11 UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 72 1e-11 UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 72 1e-11 UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob... 71 2e-11 UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 71 2e-11 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 71 2e-11 UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc... 71 2e-11 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 71 2e-11 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas... 71 2e-11 UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep... 71 2e-11 UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 71 2e-11 UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr... 71 3e-11 UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena... 71 3e-11 UniRef50_Q0B2G1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11 UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom... 71 3e-11 UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006... 71 3e-11 UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=... 71 3e-11 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 70 4e-11 UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 70 4e-11 UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3... 70 4e-11 UniRef50_Q13GX3 Cluster: Putative short-chain dehydrogenase/redu... 70 4e-11 UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11 UniRef50_A6T789 Cluster: Putative short-chain dehydrogenase/redu... 70 4e-11 UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11 UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob... 70 4e-11 UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 70 4e-11 UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11 UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 70 4e-11 UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 70 4e-11 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 70 6e-11 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 70 6e-11 UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas... 70 6e-11 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 70 6e-11 UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 70 6e-11 UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena... 70 6e-11 UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A0XX22 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 70 6e-11 UniRef50_Q9VYU9 Cluster: CG9360-PA; n=12; Diptera|Rep: CG9360-PA... 70 6e-11 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 70 6e-11 UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 70 6e-11 UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ... 69 8e-11 UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 69 8e-11 UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu... 69 8e-11 UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 69 8e-11 UniRef50_Q1IP02 Cluster: Short-chain dehydrogenase/reductase SDR... 69 8e-11 UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 69 8e-11 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 69 8e-11 UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 8e-11 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 8e-11 UniRef50_UPI0000DB6B86 Cluster: PREDICTED: similar to CG9360-PA;... 69 1e-10 UniRef50_UPI000050F9D4 Cluster: COG1028: Dehydrogenases with dif... 69 1e-10 UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif... 69 1e-10 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 69 1e-10 UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena... 69 1e-10 UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 69 1e-10 UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 69 1e-10 UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb... 69 1e-10 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc... 69 1e-10 UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu... 69 1e-10 UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 69 1e-10 UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 69 1e-10 UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 69 1e-10 UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 69 1e-10 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 69 1e-10 UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 69 1e-10 UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 69 1e-10 UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi... 69 1e-10 UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f... 69 1e-10 UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 69 1e-10 UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ... 69 1e-10 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc... 69 1e-10 UniRef50_A1T7K9 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 69 1e-10 UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q6IDG8 Cluster: RH36352p; n=2; Drosophila melanogaster|... 69 1e-10 UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve... 69 1e-10 UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;... 69 1e-10 UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000... 68 2e-10 UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10 UniRef50_Q930L5 Cluster: Putative; n=3; Proteobacteria|Rep: Puta... 68 2e-10 UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 68 2e-10 UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 68 2e-10 UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 68 2e-10 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 68 2e-10 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R... 68 2e-10 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 68 2e-10 UniRef50_Q3S8D5 Cluster: Putative short-chain dehydrogenase/redu... 68 2e-10 UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida... 68 2e-10 UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 68 2e-10 UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 68 2e-10 UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;... 68 2e-10 UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C... 68 2e-10 UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 68 2e-10 UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat... 68 2e-10 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 68 2e-10 UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13... 68 2e-10 UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 68 2e-10 UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 68 2e-10 UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 68 2e-10 UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill... 68 2e-10 UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc... 68 2e-10 UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 68 2e-10 UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10 UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari... 68 2e-10 UniRef50_Q75DB1 Cluster: ABR248Wp; n=4; Eremothecium gossypii|Re... 68 2e-10 UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 68 2e-10 UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 68 2e-10 UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 67 3e-10 UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re... 67 3e-10 UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas... 67 3e-10 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 67 3e-10 UniRef50_Q7UJY8 Cluster: Probable short-chain dehydrogenase; n=1... 67 3e-10 UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 67 3e-10 UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact... 67 3e-10 UniRef50_Q2IVE1 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 67 3e-10 UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 67 3e-10 UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2; Bacteri... 67 3e-10 UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 67 3e-10 UniRef50_A3JK09 Cluster: Oxidoreductase; n=1; Marinobacter sp. E... 67 3e-10 UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb... 67 3e-10 UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh... 67 3e-10 UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=... 67 3e-10 UniRef50_A4XEV7 Cluster: Short-chain dehydrogenase/reductase SDR... 44 4e-10 UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ... 67 4e-10 UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogena... 67 4e-10 UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 67 4e-10 UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr... 67 4e-10 UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=... 67 4e-10 UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei... 67 4e-10 UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_A6C1M0 Cluster: Short chain dehydrogenase; n=1; Plancto... 67 4e-10 UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_A0YDM1 Cluster: Putative 3-ketoacyl-CoA reductase; n=3;... 67 4e-10 UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 67 4e-10 UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family memb... 67 4e-10 UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena... 66 5e-10 UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin... 66 5e-10 UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 66 5e-10 UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 66 5e-10 UniRef50_Q84EX5 Cluster: R-specific alcohol dehydrogenase; n=5; ... 66 5e-10 UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-10 UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 66 5e-10 UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 66 5e-10 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1... 66 5e-10 UniRef50_A5P5M1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_A4WBV4 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 66 5e-10 UniRef50_Q16Q07 Cluster: Alcohol dehydrogenase, putative; n=1; A... 66 5e-10 UniRef50_A0D0S7 Cluster: Chromosome undetermined scaffold_33, wh... 66 5e-10 UniRef50_Q0U1A7 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-10 UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 66 5e-10 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 66 7e-10 UniRef50_Q9RKB7 Cluster: Probable 3-oxoacyl-[acyl carrier protei... 66 7e-10 UniRef50_Q8UAB0 Cluster: Dehydrogenase; n=1; Agrobacterium tumef... 66 7e-10 UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 66 7e-10 UniRef50_Q2SKD5 Cluster: Short-chain dehydrogenase of various su... 66 7e-10 UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 66 7e-10 UniRef50_Q3W7K4 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 66 7e-10 UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protei... 66 7e-10 UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke... 66 7e-10 UniRef50_A3SL40 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10 UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein... 66 7e-10 UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 66 7e-10 UniRef50_Q6CFW0 Cluster: Yarrowia lipolytica chromosome B of str... 66 7e-10 UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=... 66 7e-10 UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro... 66 7e-10 UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya... 66 9e-10 UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei... 66 9e-10 UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 66 9e-10 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q2S467 Cluster: NAD-binding domain 4, putative; n=1; Sa... 66 9e-10 UniRef50_Q2KXQ0 Cluster: Probable short chain dehydrogenase/redu... 66 9e-10 UniRef50_Q7P5A9 Cluster: Ketoacyl reductase hetN; n=3; Fusobacte... 66 9e-10 UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q1BF92 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q1AYC7 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh... 66 9e-10 UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10 UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 66 9e-10 UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei... 66 9e-10 UniRef50_A0LJK6 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q9SBM0 Cluster: Wts2L; n=3; core eudicotyledons|Rep: Wt... 66 9e-10 UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 66 9e-10 UniRef50_A2YPN0 Cluster: Putative uncharacterized protein; n=3; ... 66 9e-10 UniRef50_Q4P1P4 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10 UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10 UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 66 9e-10 UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 66 9e-10 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 65 1e-09 UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena... 65 1e-09 UniRef50_Q89V28 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 65 1e-09 UniRef50_Q73Q46 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 65 1e-09 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena... 65 1e-09 UniRef50_A7IJL6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;... 65 1e-09 UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09 UniRef50_Q5AX52 Cluster: Putative uncharacterized protein; n=2; ... 65 1e-09 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 65 1e-09 UniRef50_Q04520 Cluster: Acetoin(diacetyl) reductase; n=1; Raoul... 65 1e-09 UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 65 2e-09 UniRef50_Q6MBQ9 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09 UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09 UniRef50_Q1NAA1 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q11K25 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 >UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 274 Score = 178 bits (433), Expect = 1e-43 Identities = 87/199 (43%), Positives = 128/199 (64%), Gaps = 1/199 (0%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 218 DKV +TG A G+G +V+ LL E +H+A LD+A+ G +L+A+L K+G + KF + Sbjct: 14 DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398 DV DE V+ + +D VIN+AA+++ + + I++N T + STLKA++I Sbjct: 74 DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133 Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578 MG GG GG ++N+SS+ AL + +P+Y ATK+AVLQFS +G E F++T VRVL+V Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVRVLSV 193 Query: 579 CLGATDTALLTDEKLGTFD 635 CLG TDTA+L L FD Sbjct: 194 CLGPTDTAILYKNNLTKFD 212 >UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Neoptera|Rep: Putative alcohol dehydrogenase - Gryllotalpa orientalis (Oriental mole cricket) Length = 266 Score = 158 bits (383), Expect = 1e-37 Identities = 81/207 (39%), Positives = 120/207 (57%), Gaps = 1/207 (0%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215 K K +TG ATGIG + V+ LL GV+ +A+ D+ E G + +LN ++G K F + Sbjct: 4 KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395 DVT+++ G+D+VINNA +++DS ++ I +NVTA+ T A + Sbjct: 64 CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121 Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 +MGK+ GG+GG V+N++S+ L P+Y ATK AV+ S G P HF +TGVRVLT Sbjct: 122 LMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVLT 181 Query: 576 VCLGATDTALLTDEKLGTFDKYLXSSC 656 +C G TDT L+++ F L C Sbjct: 182 MCPGVTDTPLISEAHHRQFTDDLGKEC 208 >UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep: Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 270 Score = 153 bits (372), Expect = 3e-36 Identities = 80/205 (39%), Positives = 125/205 (60%), Gaps = 5/205 (2%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215 KDKV +TGAA G+G S V IL+ G K +A++D+ + G+ L+ LN +YG N+ +FY Sbjct: 4 KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395 +DV+ EE F G+L +V++ G ID++ NNA ++N+ ++K I +N+ ++ T A+E Sbjct: 63 ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKH--WEKTIAINLGGVVRGTYLALE 120 Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 M K +GG GG ++NV+S+A L V PIY ATK V+ FS + S GVR+ Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180 Query: 576 VCLGATDTALL----TDEKLGTFDK 638 +C T+LL ++E G+F + Sbjct: 181 LCPWFVKTSLLSLLNSEEHTGSFSQ 205 >UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 266 Score = 147 bits (357), Expect = 2e-34 Identities = 74/182 (40%), Positives = 117/182 (64%), Gaps = 1/182 (0%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215 KDK V ITG A+G+G ++ R LL G IA++D AEE+G+ LN ++G N+T FY Sbjct: 4 KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395 ++ + F V+ GG+++++NNA + N++ + K I+VNVT++I +TL I+ Sbjct: 63 CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETD--FMKTIDVNVTSVIRATLLGIQ 120 Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 M K GGKGG ++N+SS+A L + +P+Y ATK AV+ FS +P H+ +TGV++L Sbjct: 121 QMQKDLGGKGGAIVNISSLAGLYAAPQLPVYSATKHAVVSFSRSFAQPYHYKRTGVKILV 180 Query: 576 VC 581 +C Sbjct: 181 MC 182 >UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 329 Score = 142 bits (344), Expect = 7e-33 Identities = 69/195 (35%), Positives = 115/195 (58%), Gaps = 1/195 (0%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215 KDK + GA G+G + + LL GV + ++D+ E G++ LN ++G N+ F + Sbjct: 71 KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395 DVT F V G +D+++NNAA++ D + ++ I+ NVTA+ +++ ++ Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188 Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 MGK +GGKGG ++NV+SV L +PIY AT AV+ FS +P H+ +TGVR++ Sbjct: 189 QMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLMV 248 Query: 576 VCLGATDTALLTDEK 620 +C G T++ +L + K Sbjct: 249 LCPGLTESPMLENLK 263 >UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 271 Score = 142 bits (343), Expect = 9e-33 Identities = 73/202 (36%), Positives = 118/202 (58%), Gaps = 8/202 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKF 209 E +KV+ ITG G+G + LL+ G K +A+ D+ E GQS +L+ ++G + F Sbjct: 2 EISNKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGF 61 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI------ 371 Y D+ + F N ++++ G IDV+INNA + N+ ++ + VNV + I Sbjct: 62 YPGDIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQN--IERLVNVNVVSSIDKNILR 119 Query: 372 -TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 + L A+ MGKH GGKGG ++NV+++ L ++P Y ATK A++ F+ C+ E+F Sbjct: 120 ASQILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCM--KENF 177 Query: 549 SKTGVRVLTVCLGATDTALLTD 614 + TGVRV++VC G T T L+ + Sbjct: 178 ATTGVRVMSVCPGVTKTNLIKE 199 >UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 263 Score = 141 bits (342), Expect = 1e-32 Identities = 74/205 (36%), Positives = 118/205 (57%), Gaps = 1/205 (0%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-K 200 M+ K+K ITG G+G + LL+ G K +A+LD++ GQ L ++G K Sbjct: 1 MTDNIKNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGK 60 Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380 FY DV++ F + VV + G+D+VINNA + ND +++ + +NV +I + Sbjct: 61 AIFYACDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGS 118 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 L A + M K GGKGGT++N++S+ AL + P+Y A+K VL FS + R +++ TG Sbjct: 119 LLAFDHMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLAR--YYNNTG 176 Query: 561 VRVLTVCLGATDTALLTDEKLGTFD 635 +R+L +C G T T+LL + +FD Sbjct: 177 IRILIMCPGVTTTSLLENPLSKSFD 201 >UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 261 Score = 140 bits (338), Expect = 4e-32 Identities = 69/191 (36%), Positives = 117/191 (61%), Gaps = 1/191 (0%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 +KV ITG A GIG ++V+ LL+ G+K +A+ D+ + + +L KYGN+ + Y D Sbjct: 5 NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 398 VT++ F + V++ ID+++NNA + +D I+ + I++N A++ +L IE Sbjct: 65 VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121 Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578 +GKH GGKGG ++N +S+ L +P+Y +TK AV+ F+ C+ + TGVRV+ + Sbjct: 122 LGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCL--DVQYDTTGVRVVAI 179 Query: 579 CLGATDTALLT 611 C G T+T L++ Sbjct: 180 CPGVTETPLVS 190 >UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 279 Score = 137 bits (331), Expect = 3e-31 Identities = 74/204 (36%), Positives = 116/204 (56%), Gaps = 2/204 (0%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE--AGQSLQAELNSKYGNKTKFY 212 KDKV+ +TG A GIG V L++G +++AILDI E LQ E + ++ Y Sbjct: 11 KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPENFTADKLQEEFGT---HRVDLY 67 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392 D+ +EE F V+++ +D++IN+A + N++ + ++VNV I L AI Sbjct: 68 HCDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAI 125 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 E MGKH GG+GG V+NV+SV L HV+P+Y A+K A++ F+ + + + GV+++ Sbjct: 126 EHMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKII 183 Query: 573 TVCLGATDTALLTDEKLGTFDKYL 644 VC G T T L + + T YL Sbjct: 184 AVCPGHTRTKLNFELAVETSVNYL 207 >UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 273 Score = 132 bits (319), Expect = 7e-30 Identities = 67/192 (34%), Positives = 117/192 (60%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E KDKVV ITG +GIG S+ + +L G K++A+ ++ E + + EL+ +Y ++ FY Sbjct: 19 EVKDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFY 78 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392 DVT + + V++ ID++INNA + +D+ + ++++N+ AL+ ++ K I Sbjct: 79 PCDVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFI 136 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 +GKH GGKGG ++N++S+A + S +P+Y ATK V+ F+ + + TGVRVL Sbjct: 137 ARIGKHKGGKGGVIVNIASIAGIV-SGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVL 193 Query: 573 TVCLGATDTALL 608 +C T+T ++ Sbjct: 194 AICPSFTNTPIV 205 >UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 266 Score = 132 bits (319), Expect = 7e-30 Identities = 72/193 (37%), Positives = 112/193 (58%), Gaps = 3/193 (1%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI--AEEAGQSLQAELNSKYG-NKTKF 209 KDKV +TG GIG + V+ LL G K++AI D+ S ++ ++G +K F Sbjct: 4 KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389 Y DVT + F + +V Q +D+++N A++ ++ + I++N+TA++T TL Sbjct: 64 YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121 Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 I+ MG+H G+GG ++NV SV LT S PIY ATK V F+ + +H+ GVRV Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSL--KDHYEHLGVRV 179 Query: 570 LTVCLGATDTALL 608 + VC G T+T+LL Sbjct: 180 MAVCPGLTETSLL 192 >UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1 - Apis mellifera Length = 264 Score = 130 bits (315), Expect = 2e-29 Identities = 63/188 (33%), Positives = 112/188 (59%), Gaps = 1/188 (0%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 221 K+ +TG A GIG R LL G K +A+LD+++ G+S A+LN+++G ++ F D Sbjct: 6 KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401 V+ E F V+ +++++N A +M+D+ ++ +++N ++ T+ + M Sbjct: 66 VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDAD--WEIMVDINYKGIVYGTILGLHTM 123 Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581 GK+ GG GG ++N+SSVA L + PIY T+ A++ F+ + ++ KTG+R+LT+C Sbjct: 124 GKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRMLTIC 181 Query: 582 LGATDTAL 605 G T TA+ Sbjct: 182 PGLTTTAM 189 >UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) - Tribolium castaneum Length = 312 Score = 129 bits (311), Expect = 7e-29 Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 1/202 (0%) Frame = +3 Query: 6 IYGTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS 185 +Y +L + V ITG A GIG ++ R+ L G+ +A+ D ++E G+ +L Sbjct: 40 VYYSLGRTLSLDQNVAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLAC 99 Query: 186 KYG-NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVT 362 ++G NK F+ D++ + F + + +++V+NNA +MND ++ + N++ Sbjct: 100 EFGENKVLFFDGDMSQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVN--WECQVNTNLS 157 Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542 I TL ++ M K S G+GGT+INV+S+ L S PI+ T+ ++ FS IG Sbjct: 158 GTIIGTLLGMQYMSKTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLN 217 Query: 543 HFSKTGVRVLTVCLGATDTALL 608 HF +TGVRV +C G T+T LL Sbjct: 218 HFDRTGVRVTALCPGLTNTKLL 239 >UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 263 Score = 127 bits (306), Expect = 3e-28 Identities = 70/193 (36%), Positives = 114/193 (59%), Gaps = 3/193 (1%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS-LQAE-LNSKYGN-KTKF 209 K+KV+ ITG G+ + ++LL ++IA+ D E+ + LQ + ++G + F Sbjct: 4 KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389 Y SDV ++ F + V++ +D++IN A ++ D+ + I+VN L+ TL A Sbjct: 64 YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121 Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 I+ MG H GG+GGT+INVSS+ L P+Y ATK AV+ F+N + H++KTGVR Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVRA 179 Query: 570 LTVCLGATDTALL 608 +T+C G T T+++ Sbjct: 180 MTMCPGLTSTSMI 192 >UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 267 Score = 126 bits (305), Expect = 4e-28 Identities = 74/201 (36%), Positives = 119/201 (59%), Gaps = 4/201 (1%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGQSLQAELNSKYGNKT 203 E K+KV +TG GIG V+ L+ ++ +AI+D+ + EA + ++LN ++G + Sbjct: 2 EIKNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGS 61 Query: 204 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380 ++Y D+T+ + F I V+ + +D++IN A ++ND+ I VN TA++ S+ Sbjct: 62 YQYYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSS 119 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + AIE M K GGKGG V+NV+S+A + PIY ATK AV+ F+ + +P H G Sbjct: 120 MIAIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL-KP-HNKIIG 177 Query: 561 VRVLTVCLGATDTALLTDEKL 623 VRV+ +C G TDT L+ + L Sbjct: 178 VRVVCICPGVTDTGLVAFDHL 198 >UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 289 Score = 125 bits (301), Expect = 1e-27 Identities = 80/209 (38%), Positives = 112/209 (53%), Gaps = 3/209 (1%) Frame = +3 Query: 18 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG- 194 LK +E + KVV ITGAA GIG ++ L G K I ILDI G ELN KYG Sbjct: 25 LKKENEIEGKVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGK 84 Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 374 NK +F D+T + I + ++ +DV++NNA + + +K + N A I Sbjct: 85 NKAEFIECDITKDLE--RISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIE 140 Query: 375 STLKAIEIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 +LK +E M K GKGGT+IN++S P Y TK A++ FS +G ++ Sbjct: 141 FSLKFMENMRKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYK 200 Query: 552 KTGVRVLTVCLGATDTAL-LTDEKLGTFD 635 K GVRVLT+C G T+T L L + K+ + D Sbjct: 201 KNGVRVLTICPGETNTTLGLDNTKVNSED 229 >UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep: CG4899-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 278 Score = 124 bits (300), Expect = 1e-27 Identities = 66/198 (33%), Positives = 112/198 (56%) Frame = +3 Query: 21 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNK 200 KMS K+ VV TG A GIG V + LL G +AI+D+ + + ++ + Sbjct: 17 KMSFRGKNAVV--TGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRA-AHPTQS 73 Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380 + DV +++ + + G ID+V+N A + ND ++ + VN+ +I ST Sbjct: 74 VMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINST 131 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 L A+ MGK +GGKGG V+N+SSV L ++P+Y ATK+ ++ F+ C+ +++ ++G Sbjct: 132 LSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSG 191 Query: 561 VRVLTVCLGATDTALLTD 614 ++ +TVC GAT T + T+ Sbjct: 192 IKFVTVCPGATMTDMFTN 209 >UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin dehydrogenase [NAD+] - Homo sapiens (Human) Length = 266 Score = 122 bits (295), Expect = 6e-27 Identities = 66/204 (32%), Positives = 116/204 (56%), Gaps = 5/204 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 221 KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401 V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122 Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581 K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182 Query: 582 LGATDTALL----TDEKLGTFDKY 641 G +TA+L +E +G + +Y Sbjct: 183 PGFVNTAILESIEKEENMGQYIEY 206 >UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 337 Score = 121 bits (291), Expect = 2e-26 Identities = 64/200 (32%), Positives = 111/200 (55%), Gaps = 1/200 (0%) Frame = +3 Query: 18 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG- 194 L++S K V ITG A G+G + L G I I+DI + AG+ + A + +G Sbjct: 37 LEISGVVSGKNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGV 96 Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 374 K F +DV+ + V+ +D+V+NNA ++++ +++ I VN+ +I+ Sbjct: 97 GKVIFIHADVSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERR--WEREIAVNLNGMIS 154 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 L +++ MG+ GG+GG ++NV+ + + +P+Y ATK A++ S + P + + Sbjct: 155 VALLSMQYMGRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTER 214 Query: 555 TGVRVLTVCLGATDTALLTD 614 TGVRV+T+C G T+TAL D Sbjct: 215 TGVRVITLCPGLTETALTID 234 >UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|Rep: ENSANGP00000013280 - Anopheles gambiae str. PEST Length = 183 Score = 120 bits (290), Expect = 2e-26 Identities = 67/183 (36%), Positives = 96/183 (52%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K+KV +TGAATG+G + LL G K + I D+ +AG+ EL +YG + F Sbjct: 4 KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398 DVTD F V +++VINNA +MND+ ++ ++VN+ I TL A + Sbjct: 63 DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNF--WELEVDVNLNGAIRGTLLAQKF 120 Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578 M K G GG ++N+ S ++T PIY ATK A+L + G P H + T VR Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFAY 180 Query: 579 CLG 587 C G Sbjct: 181 CPG 183 >UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial - Strongylocentrotus purpuratus Length = 298 Score = 120 bits (289), Expect = 3e-26 Identities = 67/202 (33%), Positives = 113/202 (55%), Gaps = 2/202 (0%) Frame = +3 Query: 21 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-N 197 K+ + + V ITGAA G G++ LL V+ I I+D G++ + ELN KYG + Sbjct: 37 KIKMKIQGAVALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGED 96 Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 377 K +F++ DV+ ++ + ++ GID+V NNA + D + ++K ++V++ A++ Sbjct: 97 KVRFFQCDVSSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRG 154 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH-FSK 554 T A + M K+ GG+GG VIN++S+A L + P Y A K VL FS + + F+ Sbjct: 155 TFLAKQYMDKNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNP 214 Query: 555 TGVRVLTVCLGATDTALLTDEK 620 VR+ +C ++TA+L K Sbjct: 215 ENVRLNCLCPSFSETAILQQMK 236 >UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD); n=2; Tribolium castaneum|Rep: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium castaneum Length = 479 Score = 120 bits (289), Expect = 3e-26 Identities = 62/199 (31%), Positives = 109/199 (54%), Gaps = 2/199 (1%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-K 200 M + +KV I+GAA+GIG ++ + LL G++ + I D+ +E G+ E+ +++G+ + Sbjct: 1 MPFDINNKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGR 60 Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380 F +DV+ + F + ID+++N A ++NDSI +++ I +NV + Sbjct: 61 AIFVLTDVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSI--WQQEIAINVNGTVHGI 118 Query: 381 LKAIE-IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 L A+E + K+ G ++N SS+A + PIY TK A+ + G H+ +T Sbjct: 119 LLALENYIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERT 178 Query: 558 GVRVLTVCLGATDTALLTD 614 VR++ +C G TDT LL D Sbjct: 179 KVRIMAICPGPTDTPLLRD 197 Score = 94.7 bits (225), Expect = 2e-18 Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%) Frame = +3 Query: 90 VVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSDVTDEEHFLGILNAVV 266 +VR G + I DI E G+ + E+ +++G NK + +DVT + + + Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292 Query: 267 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 443 + +D+V+N A ++N+ +++ +++N+ + T+ A+E + K+ G G ++N+ Sbjct: 293 ETFQNLDIVVNGAGIVNELD--WQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350 Query: 444 SSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCLGATDT 599 SS A L PIY TK AV+ S G H+ +T VRVLT C G T+T Sbjct: 351 SSAAILDCFPPYPIYTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTET 402 >UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4899-PA, isoform A - Tribolium castaneum Length = 295 Score = 114 bits (275), Expect = 2e-24 Identities = 64/191 (33%), Positives = 97/191 (50%), Gaps = 1/191 (0%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 221 KV ITG + GIG +V +L E K++A++ + G+ LNS YG NK F+ D Sbjct: 52 KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401 V + N V++E G ID+VIN A + + ++K I N+ I TL+A +M Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRC--WEKEIMTNLVGTIHCTLEAYRVM 169 Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581 K G GG ++N S + + P A+ ++ S G +F TGVRV+T+C Sbjct: 170 SKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVVTLC 229 Query: 582 LGATDTALLTD 614 G T+T + D Sbjct: 230 PGITNTNFIKD 240 >UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 268 Score = 107 bits (256), Expect = 3e-22 Identities = 62/192 (32%), Positives = 104/192 (54%), Gaps = 4/192 (2%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGQSLQA--ELNSKYG-NKTKF 209 +KV +TG GIG +V+ L G K +AI D+ EE + + A +L ++ + + Sbjct: 5 NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALKQLEQEFAAQRFSY 64 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389 Y DVT+ + F+ + V G +D+++NNA + + + VN T++I T+ A Sbjct: 65 YCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMHA 122 Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 IE MG + GGKGG ++ + S+ AL +P+Y ATK A+ F ++ +K GVR+ Sbjct: 123 IERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVR--STKDYNAKYGVRI 180 Query: 570 LTVCLGATDTAL 605 + +C G T T + Sbjct: 181 VCLCPGMTKTKM 192 >UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG18814-PA - Drosophila melanogaster (Fruit fly) Length = 285 Score = 106 bits (254), Expect = 5e-22 Identities = 70/217 (32%), Positives = 114/217 (52%), Gaps = 18/217 (8%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS-D 221 K V G GIG+ V+ LL + +K +AI D+ + L AE ++ + FY+ D Sbjct: 6 KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 362 +T + A ++ G DVV+N + L++D +I I +E+ ++ Sbjct: 64 ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123 Query: 363 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533 +I STL A+E M K GG+GG ++N+SSVA L + +M IY +K+ V F+ + Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 183 Query: 534 RPEHFSKTGVRVLTVCLGATDTALLTD-EKLGTFDKY 641 P H++ +GV +T+C G T+T +L D +K TF Y Sbjct: 184 SPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFY 220 >UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Tribolium castaneum Length = 255 Score = 103 bits (246), Expect = 5e-21 Identities = 60/192 (31%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E K KV +TG A+GIG ++VR LL G+K ++++DI+E EL ++ F Sbjct: 3 ELKGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISENT------ELQD---SRVTFI 53 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392 ++DVT ++ + V +D+V+NNA ++ D I +K+ I++N+ A+I T A+ Sbjct: 54 KTDVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLAL 111 Query: 393 EI-MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 + K+ G ++N +SV L PIY +K V+ +G P + + VR+ Sbjct: 112 RTYLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRI 171 Query: 570 LTVCLGATDTAL 605 +T+C G DT + Sbjct: 172 VTICPGLVDTPM 183 >UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobacteria|Rep: Putative dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 267 Score = 101 bits (241), Expect = 2e-20 Identities = 68/211 (32%), Positives = 107/211 (50%), Gaps = 10/211 (4%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M KV +++GAA+GIG ++ R+ EG + + D+ E G+++ A + + G + Sbjct: 1 MKQNLSGKVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRA 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 365 F DV+DE + L V+E GG+D+++NNA L + + K + VNV Sbjct: 59 LFIHHDVSDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAG 118 Query: 366 LITSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542 +I AI M S GKGG++IN+SSVA L + + +Y ATK AV S Sbjct: 119 VILGHKHAIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVEC 178 Query: 543 HFSKTGVRVLTVCLGATDTAL---LTDEKLG 626 G+RV ++ G DT + L D+ +G Sbjct: 179 GRLGYGIRVNSIHPGLVDTDMGVKLVDDFVG 209 >UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans|Rep: Oxidoreductase - Triatoma infestans (Assassin bug) Length = 252 Score = 98.3 bits (234), Expect = 1e-19 Identities = 67/196 (34%), Positives = 105/196 (53%), Gaps = 8/196 (4%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 WKD+V +TGA+ GIGE++ R L + G+K +A L + Q LQ + N+ G+ K Y+ Sbjct: 4 WKDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYK 61 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITS 377 DVT+E + ++V + G I V++NNA L M D S G ++ E NV L+T Sbjct: 62 CDVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTF 121 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVA--ALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 T +EIM KH+ G +IN++S+A + M Y A+K AV + + Sbjct: 122 TQHVVEIMKKHN-ITDGHIININSLAGHVIIPKPGMANYTASKHAVTVLTESLKNELAAM 180 Query: 552 KTGVRVLTVCLGATDT 599 K+ +RV ++ G +T Sbjct: 181 KSKIRVTSISPGLVNT 196 >UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; Planctomyces maris DSM 8797|Rep: Probable putative oxidoreductase - Planctomyces maris DSM 8797 Length = 270 Score = 96.3 bits (229), Expect = 6e-19 Identities = 62/196 (31%), Positives = 96/196 (48%), Gaps = 3/196 (1%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 ++D+VV +TG + GIGE R+ EG H+AIL AGQ L ELN K F + Sbjct: 18 FQDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQ 76 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLK 386 DV + E ++ VV++ G +D +INNA + ++ + + +IE + ST Sbjct: 77 CDVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFA 136 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 + H GT+IN+SS+ A+ H Y +TK A + F+ + + GVR Sbjct: 137 GAKYALPHLRKTKGTIINMSSMTAVLGQHHSTAYCSTKGAQVSFTKSLA--IELGEAGVR 194 Query: 567 VLTVCLGATDTALLTD 614 V + DT L+ D Sbjct: 195 VNAILPSNIDTPLMRD 210 >UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR; n=10; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 282 Score = 95.9 bits (228), Expect = 8e-19 Identities = 58/206 (28%), Positives = 104/206 (50%), Gaps = 8/206 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E + +V +TG A+GIG V + EG K + I D+ +E G++L + G F+ Sbjct: 8 ELQGRVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFH 62 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTAL 368 +DV D+E +++ V+ G +DV++NNA L N+ + + + + VN+ ++ Sbjct: 63 HTDVGDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSV 122 Query: 369 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 + T A M +H GG ++IN+SS+ + +P+Y A+K+A+L F+ C Sbjct: 123 MAGTRDAGRYMSEHGGG---SIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAA--IEL 177 Query: 549 SKTGVRVLTVCLGATDTALLTDEKLG 626 + +RV + G T +L G Sbjct: 178 AHYDIRVNCIAPGNIPTPILQSSATG 203 >UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophora|Rep: Alcohol dehydrogenase - Bactrocera oleae (Olive fruit fly) Length = 258 Score = 95.5 bits (227), Expect = 1e-18 Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 2/188 (1%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--QSLQAELNSKYGNKTKFYRSD 221 VVF+ G IG + ++ + V + D+ E A ++LQA +N K K + + D Sbjct: 8 VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401 +T++ V+ + IDV++N A ++ D + + +N+ LI +TL+AI +M Sbjct: 64 ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121 Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581 K+ G+GG ++N++SV L + IY A+K V+ FS I P +++ TG+ V T C Sbjct: 122 DKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVATFC 181 Query: 582 LGATDTAL 605 G T+T L Sbjct: 182 PGLTETPL 189 >UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=7; Alphaproteobacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Caulobacter crescentus (Caulobacter vibrioides) Length = 261 Score = 94.7 bits (225), Expect = 2e-18 Identities = 58/169 (34%), Positives = 91/169 (53%), Gaps = 7/169 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF-YRSD 221 K FITG A G+G + R+L EG K +A+ DI Q++ E+N+ +G T F + D Sbjct: 11 KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 383 VT E+ ++ +L GG+ V++NNA + D G++KK + VNV ++ Sbjct: 70 VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530 A+ M H + G++IN+SS+A L + P Y A+K+AV S I Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGLIANGNSPAYNASKAAVWLLSKNI 175 >UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 266 Score = 94.3 bits (224), Expect = 2e-18 Identities = 61/194 (31%), Positives = 99/194 (51%), Gaps = 7/194 (3%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSDV 224 V +TG GIG ++ + LLD K + +LDI E+ G L+ Y ++ F + DV Sbjct: 7 VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 389 T + G +D++ NNA + ND + G +K I++NV +I TL Sbjct: 66 TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125 Query: 390 IEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 ++ MG G GGT++NV+S+A L + P+Y A+K AV+ + + ++ VR Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTL--TSLWATECVR 183 Query: 567 VLTVCLGATDTALL 608 V +C TDTA++ Sbjct: 184 VNCICPSFTDTAMV 197 >UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase - Yarrowia lipolytica (Candida lipolytica) Length = 291 Score = 91.9 bits (218), Expect = 1e-17 Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 8/195 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TG A G+G S+ L G+K IAILD+ ++ G +L+ YG + +FY++DV Sbjct: 46 KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 386 DEE I++ VV + G +DVV+N+A + + +++ I++N+ T Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCIGRPEHFSKTG 560 A M K G GGTV+ ++S++ + P Y A+K+AV S + ++ Sbjct: 166 AARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAAVKHLSKSLA--AEWAVHN 221 Query: 561 VRVLTVCLGATDTAL 605 +R ++ G DTAL Sbjct: 222 IRCNSISPGYMDTAL 236 >UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family protein; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 249 Score = 91.1 bits (216), Expect = 2e-17 Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 9/204 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K K + ITGA++GIGE+ L EGV ++ + EE + L+++++ + G K Sbjct: 4 KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 380 DVT +E F +++ +E G ID +INNA LM N + K ++VN+ ++ Sbjct: 63 DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + M + K G +IN+SS AA +Y ATKSAV FS + R E K Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGL-RQELAPKFN 178 Query: 561 VRVLTVCLGATDTAL---LTDEKL 623 + + ++ G DT L +TD+++ Sbjct: 179 INITSIEPGFVDTELTDTITDDEI 202 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 90.6 bits (215), Expect = 3e-17 Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 6/198 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 +DKV ITG +GIG + ++ EG K I ++D+ EE G S++AEL S+ G++ F ++ Sbjct: 4 QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 380 DVT+EE I + G +D++ NNA + + ++K +EV++ + Sbjct: 62 DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 AI+ K G ++N +S+ S Y A K+ V+ + +G ++ Sbjct: 122 QAAIKEFLK---AGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGL--EYAARN 176 Query: 561 VRVLTVCLGATDTALLTD 614 +RV +C G DTA+L D Sbjct: 177 IRVNALCPGFIDTAILGD 194 >UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae str. PEST Length = 191 Score = 90.2 bits (214), Expect = 4e-17 Identities = 58/195 (29%), Positives = 99/195 (50%), Gaps = 1/195 (0%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS + VVF G G+G ++ + LL +GVK + I+D+ E +L S Sbjct: 1 MSLAGQSAVVF--GGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALI 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380 D+++ +L + E G ID+++N+A ++ + K I T +I S Sbjct: 59 LCKICDISNRAALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSC 113 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 L A+ +M + GGKGG ++NV+S A L +P Y A+K ++ F+ +G +S+TG Sbjct: 114 LIALNLMSRAKGGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETG 173 Query: 561 VRVLTVCLGATDTAL 605 V+ + +C G T T + Sbjct: 174 VKFIIICPGGTRTRM 188 >UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus furiosus Length = 260 Score = 89.8 bits (213), Expect = 5e-17 Identities = 60/201 (29%), Positives = 103/201 (51%), Gaps = 6/201 (2%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K+KV +TG GIG ++ ++ + G K + + +I EEAG +A L + G F ++ Sbjct: 7 KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 380 DV DEE ++ V+ GG+D+++NNAA+M+ ++ +++ I VN+T + Sbjct: 65 DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 A E M K GG +IN++S AL Y A+K +L ++ + +K Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLA--ISLAKYR 179 Query: 561 VRVLTVCLGATDTALLTDEKL 623 +RV+ V G +T+ KL Sbjct: 180 IRVVAVSPGWIETSRWKKSKL 200 >UniRef50_Q2W431 Cluster: Dehydrogenase with different specificities; n=2; Magnetospirillum|Rep: Dehydrogenase with different specificities - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 248 Score = 88.6 bits (210), Expect = 1e-16 Identities = 63/201 (31%), Positives = 100/201 (49%), Gaps = 6/201 (2%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 +++DKV ITG A+GIG V+ + + G + I DI EAG+ AEL +K G K +F Sbjct: 2 KFEDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFV 59 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 374 R DVTD+ + + VV +G +D++ N A +++ K + +N+T I Sbjct: 60 RLDVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIE 119 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 +M + GK ++NV+S A S +Y A K ++ FS + R ++ Sbjct: 120 LIRAFFPLMIEKKTGK---IVNVASDAGRVGSLGESVYSAAKGGLIAFSKALAR--EGAR 174 Query: 555 TGVRVLTVCLGATDTALLTDE 617 + V +C G TDT LL E Sbjct: 175 FNINVNAICPGPTDTPLLKSE 195 >UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=2; Actinomycetales|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Mycobacterium avium (strain 104) Length = 250 Score = 88.6 bits (210), Expect = 1e-16 Identities = 57/189 (30%), Positives = 102/189 (53%), Gaps = 4/189 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGAA+GIGE+ + L ++G K + + DI E+ G+ + AE+ ++ G + F R+D+ Sbjct: 6 KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 395 + EE +++ V GG+ + NNAA+ + +++ + +V VT + + T + Sbjct: 64 SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123 Query: 396 IMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 H G GG ++N +S AAL + M Y ATK ++ + G +++ G+RV Sbjct: 124 AEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGL--DYARNGIRVN 181 Query: 573 TVCLGATDT 599 V G+ T Sbjct: 182 AVAPGSIKT 190 >UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep: Dehydrogenase - Bradyrhizobium japonicum Length = 271 Score = 88.2 bits (209), Expect = 2e-16 Identities = 59/203 (29%), Positives = 106/203 (52%), Gaps = 7/203 (3%) Frame = +3 Query: 18 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197 + M+ + + KV +TG A+GIGE++V + EG IA D+ E G L A+ +K G Sbjct: 1 MNMAGQVEGKVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPEL-AKRITKAGG 58 Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVN 356 K F DV+ EE ++ I+ + + G +D++++NA ++++ ++G ++K +N Sbjct: 59 KAIFLEQDVSSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAIN 118 Query: 357 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536 + + S + +M K GG+++ +SS+A L + + Y ATK V F+ I Sbjct: 119 LDGVFLSVKHCLPLMRKTG---GGSIVMMSSLAGLRGAPGLSAYSATKGGVRLFAKSIAM 175 Query: 537 PEHFSKTGVRVLTVCLGATDTAL 605 G+RV +V G DT + Sbjct: 176 ECAAVGDGIRVNSVHPGIIDTPI 198 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 88.2 bits (209), Expect = 2e-16 Identities = 56/200 (28%), Positives = 103/200 (51%), Gaps = 6/200 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 ++KV+ +TG + GIG+++ DEG K + + EE+ +++ E++ K G+ ++ Sbjct: 6 ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 380 DV +E+ ++N + E G +D+++NNA +M +++ + K E N + Sbjct: 65 DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 A ++M KH K G +IN+SSV + S +Y ATKS ++ F+ + + G Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAK--ELGPFG 179 Query: 561 VRVLTVCLGATDTALLTDEK 620 + V + G DT L D K Sbjct: 180 ITVNAIAPGFIDTDLTHDVK 199 >UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 269 Score = 87.8 bits (208), Expect = 2e-16 Identities = 61/190 (32%), Positives = 101/190 (53%), Gaps = 6/190 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYR 215 KDK + ITG TGIG+++ +L+ G + + I E+ ++ A++ ++ G++ Sbjct: 30 KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 380 +DVT +E IL E GGID++INNAAL N+S YK I+ N+T + Sbjct: 89 ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 +A M + K G +IN+ S++A ++ IY ATKSA+ FS + + + G Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSAESKEAKSTIYVATKSAIRGFSTSLRK--ELNPLG 203 Query: 561 VRVLTVCLGA 590 ++V + GA Sbjct: 204 IKVSLIEPGA 213 >UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=16; Bacillaceae|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Bacillus anthracis Length = 264 Score = 87.4 bits (207), Expect = 3e-16 Identities = 65/212 (30%), Positives = 107/212 (50%), Gaps = 7/212 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M+ ++KV+ ITGA++GIGE V + ++G + ++ EE ++L ++ Y Sbjct: 1 MTGRLQNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPC 59 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365 +Y DV++E + + V+QE G ID+++NNA + S+ K +VNV Sbjct: 60 YYYVLDVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFG 119 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 L+ T + M K + G +IN++S+A + Y ATK AVL F+N + R E Sbjct: 120 LVACTKAVLPYMVKRNEGH---IINIASLAGKIATPKSSAYAATKHAVLGFTNSL-RME- 174 Query: 546 FSKTGVRVLTVCLGATDTALL-TDEKLGTFDK 638 S T V V + G DT ++ GT+ K Sbjct: 175 LSSTNVFVTAINPGPIDTNFFEIADQSGTYVK 206 >UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 251 Score = 87.0 bits (206), Expect = 4e-16 Identities = 63/203 (31%), Positives = 99/203 (48%), Gaps = 6/203 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITG A G GE+ R + EG + + I D+ +EAGQ + AEL G+ +F DV Sbjct: 7 KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 386 T E + ++A + + G +D+++NNAA++ S+ Y+K I+VN Sbjct: 62 TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A +G GG+++NVSS A + Y ++K AV + F + G+R Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAAL--EFGRYGIR 176 Query: 567 VLTVCLGATDTALLTDEKLGTFD 635 V +V G DT + + FD Sbjct: 177 VNSVHPGGIDTVMARPPEFADFD 199 >UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis Length = 253 Score = 87.0 bits (206), Expect = 4e-16 Identities = 61/194 (31%), Positives = 101/194 (52%), Gaps = 6/194 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 DK V ITG A+GIG + V+ L + ++ + DI E G+++ + N+ ++ F ++D Sbjct: 5 DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 383 +TDE + + V GG+DV+INNA + + + K ++VN+T + + Sbjct: 61 ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 A++ M + GK G +IN SV L +P Y A+K VLQ + + ++K + Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA--VDYAKHQI 175 Query: 564 RVLTVCLGATDTAL 605 RV VC G DT L Sbjct: 176 RVNCVCPGIIDTPL 189 >UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp. B14905 Length = 252 Score = 86.6 bits (205), Expect = 5e-16 Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 7/198 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E +K+ +TGA +GIG + L G K + I+D +E G+ +L + G + F Sbjct: 2 EHLNKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFV 59 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 371 ++DV+ E +NA V+ G IDV NNA ++ + Y + + +NV + Sbjct: 60 QADVSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVF 119 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 I++M G G++IN +S A + H M +Y A+K AV+ + + Sbjct: 120 LGLKHVIKVM---EGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASL--EYV 174 Query: 552 KTGVRVLTVCLGATDTAL 605 K G+R+ +C G +TAL Sbjct: 175 KKGIRINAICPGGVETAL 192 >UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Short-chain dehydrogenase/reductase SDR precursor - Herpetosiphon aurantiacus ATCC 23779 Length = 247 Score = 85.4 bits (202), Expect = 1e-15 Identities = 57/195 (29%), Positives = 102/195 (52%), Gaps = 7/195 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TG A GIG + ++L +G + I DI E+ G + ++ G + F DV Sbjct: 5 KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 383 + E ++ + +QGG+D++INNA + ++ ++ +++++T + Sbjct: 63 SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 A + M +GGKGG ++NV+S+A + S + Y K+ V+Q S G E + G+ Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSK-TGAIE-LASAGI 177 Query: 564 RVLTVCLGATDTALL 608 R+ VC G T+TA+L Sbjct: 178 RINAVCPGWTETAIL 192 >UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP] reductase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 85.0 bits (201), Expect = 1e-15 Identities = 64/193 (33%), Positives = 103/193 (53%), Gaps = 2/193 (1%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M + K K ITG + GIG+S+ L +EGV +IAI +EA Q + EL K G K Sbjct: 1 MDLQLKGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKV 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITS 377 DV D E F L AV E G +D+++NNA+ M D ++ ++++++ A + + Sbjct: 59 FTQTCDVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRA 118 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 T K + M + SG G ++ +SSV+ L +S P Y A K+A++ +S + + Sbjct: 119 TKKVVPWMSE-SG--SGNILFISSVSGL-ESGSPPAYAAAKAALISYSKTMA--VQLAPQ 172 Query: 558 GVRVLTVCLGATD 596 +RV T+ GA + Sbjct: 173 HIRVNTIAPGAIE 185 >UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Sphingomonadales|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 285 Score = 85.0 bits (201), Expect = 1e-15 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 4/189 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGAA+GIG++ V L EG H+ DI E G++L N + F R DV Sbjct: 6 KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 395 T +++A + GGID+V NNAA D I + + + + ++ S I Sbjct: 61 TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120 Query: 396 IMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 H G KG +++N +SVAAL + Y K+ VL + ++ G+RV Sbjct: 121 YAAPHMKGRKGASIVNTASVAALGAGYSPTAYAVAKAGVLHLTRVAA--TDLAQYGIRVN 178 Query: 573 TVCLGATDT 599 +C G +T Sbjct: 179 AICPGFINT 187 >UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1; Apis mellifera|Rep: Short-chain dehydrogenase/reductase - Apis mellifera (Honeybee) Length = 246 Score = 85.0 bits (201), Expect = 1e-15 Identities = 53/201 (26%), Positives = 104/201 (51%), Gaps = 9/201 (4%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M W D+V +TGA +GIG+ ++ L+ +G+K I I ++ ++L EL SK G K Sbjct: 1 MEQNWIDEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KL 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365 + D++++ L ++ V + G ID++INNA L ND + +KK ++N+ Sbjct: 59 VPLQCDLSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLG 118 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALT---QSHVMPIYFATKSAVLQFSNCIGR 536 L + +++M K G G ++N++ + L + P Y A+K A+ ++C+ Sbjct: 119 LTCMIQEVLKLM-KKKGINNGIIVNINDASGLNLLPMNRNRPAYLASKCALTTLTDCLRS 177 Query: 537 PEHFSKTGVRVLTVCLGATDT 599 ++ ++V+++ +T Sbjct: 178 ELAQCESNIKVISISPDLVET 198 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 84.6 bits (200), Expect = 2e-15 Identities = 57/193 (29%), Positives = 101/193 (52%), Gaps = 6/193 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K+ +TGAA G+G ++ + L+EG + + D++EE AEL + + R DV Sbjct: 9 KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386 D E F +++A V E G +D+++NNA + S+ + + VNV+++ Sbjct: 64 GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 AI M + GG +INV+S+A L + Y A+K+AV+ F+ + +H + +R Sbjct: 124 AIPHMRRQGGG---AIINVASIAGLRGETLAAAYSASKAAVVNFTRSLAL-DH-ADENIR 178 Query: 567 VLTVCLGATDTAL 605 V +C G+ +T + Sbjct: 179 VNAICPGSVETEM 191 >UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=30; Euteleostomi|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Homo sapiens (Human) Length = 260 Score = 84.2 bits (199), Expect = 2e-15 Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 11/199 (5%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--QSLQAELNSK-YGNKTK 206 W+D++ +TGA+ GIG +V R L+ +G+K ++ A G + L AE S Y Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65 Query: 207 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 368 YR D+++EE L + +A+ + G+D+ INNA L++ S +K VNV AL Sbjct: 66 PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125 Query: 369 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPE 542 T +A + M K G +IN++S++ + V Y ATK AV + + + Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184 Query: 543 HFSKTGVRVLTVCLGATDT 599 ++T +R + G +T Sbjct: 185 REAQTHIRATCISPGVVET 203 >UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep: Blr4846 protein - Bradyrhizobium japonicum Length = 255 Score = 83.8 bits (198), Expect = 3e-15 Identities = 55/170 (32%), Positives = 87/170 (51%), Gaps = 5/170 (2%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 D+VV ITG A+GIG + VR +G + +A LDI E AG SL E+ + G F R D Sbjct: 11 DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI--- 392 + D + + V G V++NNAA ND + + +I LK + Sbjct: 70 LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127 Query: 393 --EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536 ++ + GG++IN+SS+A + +P+Y A K+A++ F+N + R Sbjct: 128 AQAVVPQMQARGGGSIINMSSIAWMRGGPALPVYAAAKAAIVGFTNSLAR 177 >UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 260 Score = 83.8 bits (198), Expect = 3e-15 Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 7/206 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 +K + ITG A+GIG + ++L G K I I D+AE+ G +L + + + F + D Sbjct: 14 NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 380 VT + V++ GG+DVVINNA + + +++ + + VNV + Sbjct: 72 VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 AI + H GG VINV+S+A L + ++ Y A+K AV+ + +++ Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPMLSAYSASKHAVIGLTK--SAAIEYARAN 186 Query: 561 VRVLTVCLGATDTALLTDEKLGTFDK 638 +R VC DT ++ + L +K Sbjct: 187 IRFNAVCPSFIDTPMVRNSMLNMNEK 212 >UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Leptospira interrogans Length = 254 Score = 83.4 bits (197), Expect = 4e-15 Identities = 58/203 (28%), Positives = 99/203 (48%), Gaps = 6/203 (2%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K K +TGAA GIG+S L G ++ I D+ EE+ ++ E++ + G K + Sbjct: 5 KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 380 +V+D + + A V E G +D+++NNA + D++ + K I VN+T T Sbjct: 64 NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 AI+ M K+ GG++IN+SS+A + + Y A+K+ V+ F+ + K Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVR 181 Query: 561 VRVLTVCLGATDTALLTDEKLGT 629 + AT+ EK+ T Sbjct: 182 CNAIAPGFIATEMTDAIPEKIRT 204 >UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa protein; n=44; Drosophiliti|Rep: Alcohol dehydrogenase-related 31 kDa protein - Drosophila melanogaster (Fruit fly) Length = 272 Score = 83.4 bits (197), Expect = 4e-15 Identities = 55/190 (28%), Positives = 93/190 (48%), Gaps = 1/190 (0%) Frame = +3 Query: 75 GIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT-DEEHFLGI 251 GI ++L+ + + +AIL E Q++ + K + F+ DVT E Sbjct: 17 GIALETSKVLMTKNIAKLAILQSTENP-QAIAQLQSIKPSTQIFFWTYDVTMAREDMKKY 75 Query: 252 LNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGT 431 + V+ + IDV+IN A L +++ I N+T ++ + + M + GG GG Sbjct: 76 FDEVMVQMDYIDVLINGATLCDENN--IDATINTNLTGMMNTVATVLPYMDRKMGGTGGL 133 Query: 432 VINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCLGATDTALLT 611 ++NV+SV L S V Y A+K V+ F+ + P ++S+ GV V+ VC G T + Sbjct: 134 IVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCG--PTRVFV 191 Query: 612 DEKLGTFDKY 641 D +L F +Y Sbjct: 192 DRELKAFLEY 201 >UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 258 Score = 83.0 bits (196), Expect = 6e-15 Identities = 59/199 (29%), Positives = 104/199 (52%), Gaps = 6/199 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 +VV I+GAA G GE R+ ++EG K + + D+ ++ G++L E+ ++Y DV Sbjct: 7 RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 386 E+ + + G ID ++NNA ++ ND +G +++ ++VN + +K Sbjct: 60 GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 + + +G GGT++N +S A LT + Y ATK A++ + + E +K +R Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTR-VAALELAAKK-IR 174 Query: 567 VLTVCLGATDTALLTDEKL 623 V VC GA DTA+ +L Sbjct: 175 VNAVCPGAIDTAMSNPSQL 193 >UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 258 Score = 83.0 bits (196), Expect = 6e-15 Identities = 55/190 (28%), Positives = 97/190 (51%), Gaps = 3/190 (1%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TG A G+G + R+ + EG + I D+ + G++L EL G+ +F R DV Sbjct: 7 KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 398 DE +++ + +A +++ G IDV++NNAA++ + K+ E V+ + T I Sbjct: 62 ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121 Query: 399 MGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 + H K G+++N+SSV L + + Y ++K V + GVRV + Sbjct: 122 IAPHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAAL--ELGHQGVRVNS 179 Query: 576 VCLGATDTAL 605 + G +TA+ Sbjct: 180 IHPGGVNTAM 189 >UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 268 Score = 83.0 bits (196), Expect = 6e-15 Identities = 57/197 (28%), Positives = 95/197 (48%), Gaps = 9/197 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGAA GIG + + L EG K + D E GQ + E+ + G T F+R DV Sbjct: 7 KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 383 TDE + ++ ++ GG+ VV+NNA + + ++ ++ IEV++ ++ Sbjct: 65 TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124 Query: 384 KAIEIMGKHS--GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 I + K++ GG GG ++N+SS+ L Y A K V + + Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECADAGY 184 Query: 558 GVRVLTVCLGATDTALL 608 +RV +V G DT ++ Sbjct: 185 NIRVNSVHPGYIDTPMV 201 >UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep: Fat body protein 2 - Drosophila melanogaster (Fruit fly) Length = 256 Score = 83.0 bits (196), Expect = 6e-15 Identities = 55/194 (28%), Positives = 98/194 (50%), Gaps = 2/194 (1%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGQSLQAELNSKYGNKTK 206 +W K V G+ +GIG ++ L+ + +K + I+ E E + LQA +N K Sbjct: 3 DWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMMKKLQA-INPSV--KVV 59 Query: 207 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 386 F + ++ ++ + + Q G IDV+IN ++ D + + +N+T +I ST+ Sbjct: 60 FMQMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKD--VETTMGMNLTGMIQSTMM 117 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A+ M K G GG V+N+SSV L + +Y A +L F+ +G + KTGV Sbjct: 118 AMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVM 177 Query: 567 VLTVCLGATDTALL 608 + +C G T++ ++ Sbjct: 178 FMAMCPGLTNSEMI 191 >UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila melanogaster (Fruit fly) Length = 256 Score = 83.0 bits (196), Expect = 6e-15 Identities = 57/189 (30%), Positives = 92/189 (48%), Gaps = 2/189 (1%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAE-LNSKYGNKTKFYRSDV 224 V+F+ G GIG + LL +K++ ILD E + + +N K FY DV Sbjct: 10 VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66 Query: 225 TDE-EHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401 T +L + + +DV+IN A +++D ++ I VN T L+ +T ++ Sbjct: 67 TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQ--IERTIAVNYTGLVNTTTAILDFW 124 Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581 K GG GG + N+ SV + +P+Y TK+AV+ F++ + + TGV TV Sbjct: 125 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVN 182 Query: 582 LGATDTALL 608 G T T L+ Sbjct: 183 PGITRTTLV 191 >UniRef50_Q28GY1 Cluster: Novel protein containing short chain dehydrogenase domain; n=4; Deuterostomia|Rep: Novel protein containing short chain dehydrogenase domain - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 255 Score = 82.6 bits (195), Expect = 8e-15 Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 9/197 (4%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF-Y 212 WK +V +TGA+ GIG +V R+L+ G+K + ++ + L AE S T F Y Sbjct: 4 WKGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKI-EKLAAECQSAGYPGTLFPY 62 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 374 + D+++EE L + +A+ G+DV INNA L++ ++ I+VNV AL Sbjct: 63 KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSI 122 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYF--ATKSAVLQFSNCIGRPEHF 548 T +A + M K G +IN++SV +F ATK V + I + Sbjct: 123 CTREAYQSM-KERNIDDGHIININSVLGHIYQCAKQAHFYCATKHTVTALTEAIRQELRE 181 Query: 549 SKTGVRVLTVCLGATDT 599 K+ +RV ++ G +T Sbjct: 182 LKSHIRVTSISPGLVET 198 >UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Leptospira interrogans Length = 256 Score = 82.6 bits (195), Expect = 8e-15 Identities = 60/204 (29%), Positives = 102/204 (50%), Gaps = 7/204 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M + KDKV +TG +TGIG++VV+ + +GVK + E G+ L++E+ ++ G Sbjct: 1 MENIMKDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDV 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVT 362 F DVT E +++A +++ G +D INNA +M N + ++ K + VN+ Sbjct: 59 YFVVCDVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLK 118 Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542 S I M K GG V+NVSS++ + + Y A K V+ + Sbjct: 119 GTWLSMKYQIPEMIKMG---GGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAAL-- 173 Query: 543 HFSKTGVRVLTVCLGATDTALLTD 614 ++K +R+ +C GA T +L + Sbjct: 174 EYAKKNIRINAICPGAVKTEILDE 197 >UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4; Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase - Comamonas testosteroni (Pseudomonas testosteroni) Length = 254 Score = 82.2 bits (194), Expect = 1e-14 Identities = 53/168 (31%), Positives = 93/168 (55%), Gaps = 6/168 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M++ + KV +TG A+G+G VV++LL EG K +A DI E AGQ L AEL G ++ Sbjct: 1 MTNRLQGKVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERS 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365 F R DV+ E + ++ AV + G ++V++NNA ++ + + + +++N + Sbjct: 56 MFVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTES 115 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 509 + + I M + GG++IN++SV++ Y A+K+AV Sbjct: 116 VFIGCQQGIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAV 159 >UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella melitensis Length = 272 Score = 81.8 bits (193), Expect = 1e-14 Identities = 59/197 (29%), Positives = 95/197 (48%), Gaps = 6/197 (3%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 +KDKVV +TG A+GIGE+ R + EG K + I D ++ GQ L EL + + F + Sbjct: 3 FKDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIK 59 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 377 +DV D ++ V+ G +D++ NA + D+ ++K I++N+T + Sbjct: 60 TDVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLC 119 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 AI+ M S G GG ++N S+ + + Y A K V + + + Sbjct: 120 DKYAIDQM--RSQG-GGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLA--IDYGPQ 174 Query: 558 GVRVLTVCLGATDTALL 608 +RV VC G DT LL Sbjct: 175 NIRVNAVCPGYIDTPLL 191 >UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 253 Score = 81.4 bits (192), Expect = 2e-14 Identities = 52/201 (25%), Positives = 102/201 (50%), Gaps = 7/201 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 KDKV +TGAA+G+G+++ + EG K + + D+ EE QS+ E+ S G T + Sbjct: 4 KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 377 ++ +E +++ V G +D+++NNA +M+ +++G + ++N ++ + Sbjct: 62 NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 KAI I + + G ++N +S L +H Y A+K AV+ + G ++ + Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTG--YMYANS 176 Query: 558 GVRVLTVCLGATDTALLTDEK 620 G+R + G T + + K Sbjct: 177 GIRCNAIAPGGVATNITSSLK 197 >UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinomycetales|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 267 Score = 81.4 bits (192), Expect = 2e-14 Identities = 59/190 (31%), Positives = 94/190 (49%), Gaps = 7/190 (3%) Frame = +3 Query: 57 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 236 +TG A G+G + L D G + I D+ EE G++ A+ K G T F + DVTD+ Sbjct: 13 VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRAT-ADSVGKTGVDTGFVKLDVTDDG 70 Query: 237 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 398 ++ + A V++ GG+D+++NNA + S+ + ++ EVN+ + + Sbjct: 71 NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130 Query: 399 MGK-HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 M + G GG ++NVSSVAA + Y ATKSAV + + + GVRV Sbjct: 131 MRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKLGYGVRVNC 190 Query: 576 VCLGATDTAL 605 V G T + Sbjct: 191 VYPGLVATEM 200 >UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Hyphomonas neptunium ATCC 15444|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Hyphomonas neptunium (strain ATCC 15444) Length = 262 Score = 81.4 bits (192), Expect = 2e-14 Identities = 53/192 (27%), Positives = 94/192 (48%), Gaps = 2/192 (1%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 +++KV ITGAA+GIG + R+L EG H+ + D+ + G+S+ A+L G + Sbjct: 6 FENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVK 60 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 389 DV+ ++ A V+ G ID++ NNA + S+ I E + + S A Sbjct: 61 CDVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYA 120 Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 H +G ++N +S++ L + Y A K AV+ ++ + +H + G+RV Sbjct: 121 CHFAIPHM-PRGSAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALA-VDH-GRDGIRV 177 Query: 570 LTVCLGATDTAL 605 +C G +T + Sbjct: 178 NALCPGLVETPI 189 >UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 275 Score = 81.4 bits (192), Expect = 2e-14 Identities = 60/196 (30%), Positives = 98/196 (50%), Gaps = 6/196 (3%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 ++ KV F+TG +G+G ++ L G IA+ DI EA + + A + G K+ + Sbjct: 4 FQGKVAFVTGGGSGLGRALSEELARRGAV-IAVTDINAEAAEHVAAAITES-GGKSCSMK 61 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITS 377 DV+ E +++VV G +D + NNA ++ +G+ + + I+VN+ ++ Sbjct: 62 LDVSQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYG 121 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 T A M + G ++N++SV L Y ATK AV+ S + RPE SK Sbjct: 122 TTAAYSHMVRQGYGH---IVNIASVGGLVPLPTYAAYAATKHAVVGLSTSM-RPE-ASKL 176 Query: 558 GVRVLTVCLGATDTAL 605 GVR+ VC G +T L Sbjct: 177 GVRITVVCPGTMNTGL 192 >UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short chain dehydrogenase family protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 273 Score = 81.4 bits (192), Expect = 2e-14 Identities = 61/194 (31%), Positives = 97/194 (50%), Gaps = 6/194 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 DKV +TG A+G+G +V +L G + I DI E+ + + A + + G T + D Sbjct: 6 DKVFIVTGGASGMGRAVCELLGTRGA-ILIIADIDGESAEKVAAGITAAGGRATGVF-LD 63 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383 T +E +++ E G +D + NNA ++ + S + + ++VN ++T TL Sbjct: 64 TTADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTL 123 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 A IM + G +IN +S A L V+ Y TK AV+ S + RPE +K GV Sbjct: 124 AAYRIMVEQGFGH---IINTASTAGLVPIPVITAYATTKHAVVGLSISL-RPE-AAKAGV 178 Query: 564 RVLTVCLGATDTAL 605 RV VC G T++ Sbjct: 179 RVSVVCPGYVSTSI 192 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 81.4 bits (192), Expect = 2e-14 Identities = 53/166 (31%), Positives = 85/166 (51%), Gaps = 6/166 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 DKVV +TG A G+G + +L EG + + D+ EE G AE+ + G K F D Sbjct: 6 DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383 VT+E H+ G ++ ++ E +D ++NNA ++ + S + + E+NV ++ T Sbjct: 64 VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 521 IE M K G ++NVSS+ L + Y A+K AV F+ Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFT 166 >UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Lin2278 protein - Listeria innocua Length = 253 Score = 81.0 bits (191), Expect = 2e-14 Identities = 52/197 (26%), Positives = 100/197 (50%), Gaps = 8/197 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGAA+G+G+ + + EG K + + D+ EA Q A + + G ++V Sbjct: 7 KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 383 T ++ ++N + G +D+++NNA +M++ + ++ K +N T ++ +T Sbjct: 65 TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124 Query: 384 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 KA+ I + KG G ++N++S L S Y A+K AV+ F+ +G ++ Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVG--FQYANKN 178 Query: 561 VRVLTVCLGATDTALLT 611 +R + GA +T + T Sbjct: 179 IRCNAIAPGAVNTNIGT 195 >UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2143 Length = 259 Score = 81.0 bits (191), Expect = 2e-14 Identities = 55/210 (26%), Positives = 96/210 (45%), Gaps = 5/210 (2%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS + +V +TG A GIG + EG+ ++ + D+ ++ G+ A + + GN Sbjct: 1 MSTTFSGQVALVTGGAAGIGRTTAAAFAREGL-NVVVADMDKDGGEETVAAIKAAGGNAI 59 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383 F DVT E ++ G +D NNA + + G K E +++ + Sbjct: 60 -FVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEK-GELSKGTEDEFDSIMAVNV 117 Query: 384 KAIEIMGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 K + + KH + GGT++N SS+ L + M IY A+K AV+ + Sbjct: 118 KGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVEN-- 175 Query: 549 SKTGVRVLTVCLGATDTALLTDEKLGTFDK 638 ++ G+R+ VC G DT + ++ FD+ Sbjct: 176 ARNGIRINAVCPGVIDTNMFNRSRM--FDR 203 >UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus iheyensis Length = 256 Score = 80.6 bits (190), Expect = 3e-14 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 +DKV +TGAA G+G++ IL E + I D EE GQ + E+ G + F + Sbjct: 7 EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEVVEEVKQA-GGQAAFIKV 64 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 377 D++D ++ V + G +D+ +NNAAL D + K I V++T T+ Sbjct: 65 DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 E+ G GG+++N+SSV+ Y A K V+ + + E+ Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTK-VAALEN-GPQ 180 Query: 558 GVRVLTVCLGATDTALL 608 +RV TV GA DT +L Sbjct: 181 NIRVNTVAPGAIDTPML 197 >UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas putida (strain KT2440) Length = 262 Score = 80.6 bits (190), Expect = 3e-14 Identities = 53/206 (25%), Positives = 97/206 (47%), Gaps = 7/206 (3%) Frame = +3 Query: 18 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197 + +++++ KVV +TGA +GIG + G +A+ DI+ + G EL G Sbjct: 1 MTVNYDFSGKVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGG 58 Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVN 356 + F+ DV E +L VV GG+D+ NNA + + + + +++ I+VN Sbjct: 59 EATFFHVDVGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVN 118 Query: 357 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536 ++++ I +M K GG ++N +S + L + + Y ATK V+ + Sbjct: 119 LSSVFYCLKGEIPLMLKRG---GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAA- 174 Query: 537 PEHFSKTGVRVLTVCLGATDTALLTD 614 ++ +R+ VC G D+ L D Sbjct: 175 -IDYANQNIRINAVCPGPVDSPFLAD 199 >UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp. SG-1 Length = 279 Score = 80.6 bits (190), Expect = 3e-14 Identities = 53/197 (26%), Positives = 97/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 ++K ITGA +G+G+S L EG+ IA++DI EE G E+ + G F ++ Sbjct: 31 ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 377 DV+ E ++ V+E G +D NNA + +N I ++ + +N+ + Sbjct: 89 DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 E+M K+ GG+++N +S A + + Y ATK ++ + + ++K Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSM--VAEYAKE 203 Query: 558 GVRVLTVCLGATDTALL 608 G+RV + G T+T ++ Sbjct: 204 GLRVNAIAPGPTETPMV 220 >UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Methylobacterium sp. 4-46 Length = 255 Score = 80.6 bits (190), Expect = 3e-14 Identities = 60/203 (29%), Positives = 97/203 (47%), Gaps = 6/203 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TG A GIG + R +EG + + DI EAG + A N + +F DV Sbjct: 7 KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 386 T + + + V +GG+DVV+N A + +S+ + +++ VNV Sbjct: 62 TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A+ +M K G+GG +IN+SSV+ + H + Y A+K AV + + G+R Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGHNLAAYNASKGAVRLLTKSVALHCARQGYGIR 180 Query: 567 VLTVCLGATDTALLTDEKLGTFD 635 ++ G T+T +L D G D Sbjct: 181 CNSIHPGFTETDMLHDLAAGGRD 203 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 80.6 bits (190), Expect = 3e-14 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 6/198 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E++ KV +TG A GIG + L EG + I D A +L +N+ +G + Sbjct: 2 EFQGKVAIVTGGAQGIGRATALALAREGAA-VVIADRDAAATTALVEGINA-WGGRALAV 59 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALIT 374 +DV+DE I N V E GGID+++NNA + + ++ ++++ I VN+T + Sbjct: 60 IADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF- 118 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 L + +M + GG ++NV+SV L Y A+K V+ + + + Sbjct: 119 --LVSRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDG--AP 174 Query: 555 TGVRVLTVCLGATDTALL 608 G+RV VC G DT+LL Sbjct: 175 DGIRVNCVCPGLIDTSLL 192 >UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 250 Score = 80.2 bits (189), Expect = 4e-14 Identities = 50/169 (29%), Positives = 90/169 (53%), Gaps = 7/169 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGAA GIG ++ + EG K + I DI + GQ + AEL G + F+ +DV Sbjct: 10 KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 383 +D +++ ++ GG+ V+ NNA + ++D + +++ + V++ ++ + Sbjct: 64 SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530 A M H GG ++N++S A +T M Y A K+ V+QF+ C+ Sbjct: 124 SAARHMVDHGGG---AIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCL 169 >UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase; n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein reductase - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 249 Score = 80.2 bits (189), Expect = 4e-14 Identities = 59/205 (28%), Positives = 102/205 (49%), Gaps = 8/205 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M+ KDKV ITG GIG + + EG K + + + G++ A K+G+ Sbjct: 1 MTDRLKDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAVA----KFGDDV 56 Query: 204 K-FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNV 359 F + DV+ E + +++A + + G +D+++NNA + +N +I ++K I+VN+ Sbjct: 57 SLFVQQDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNL 116 Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539 TA AI+ M K + G++INVSSVA L + P Y A+K ++ Sbjct: 117 TANFLGEKAAIKAM-KQTADAKGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALN 175 Query: 540 EHFSKTGVRVLTVCLGATDTALLTD 614 +RV +V G DT+++ + Sbjct: 176 LAQRGIDIRVNSVHPGWIDTSIVPE 200 >UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8; Bacteria|Rep: Short-chain alcohol dehydrogenase - Burkholderia dolosa AUO158 Length = 284 Score = 80.2 bits (189), Expect = 4e-14 Identities = 60/195 (30%), Positives = 101/195 (51%), Gaps = 7/195 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 +KVV ITGA++GIGE+ ++L +G +A+ + Q + AE+ +K G + ++ D Sbjct: 44 NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 383 VTD+E ++N VV + G +DV++NNA LM + + + K + I++N+ L+ Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAAL-TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 A+ + K + G +N++SV L S +Y TK AV S + H Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGLKVFSPGGTVYSGTKFAVRAISEGL---RHEVGGN 215 Query: 561 VRVLTVCLGATDTAL 605 +R + GA DT L Sbjct: 216 IRTTVISPGAIDTEL 230 >UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=5; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 261 Score = 80.2 bits (189), Expect = 4e-14 Identities = 61/200 (30%), Positives = 94/200 (47%), Gaps = 8/200 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 +V +TG A+GIG + L EG++ + +LDI A +++ AE G R DV Sbjct: 6 RVALVTGGASGIGRATAGRLAAEGMR-VCVLDIDGPATEAV-AESIGGIG-----LRCDV 58 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND---SIGI-----YKKAIEVNVTALITST 380 TD E + V E GG+DV NA + D IG Y+K++ VNV ++ Sbjct: 59 TDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDGVVFGV 118 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 A+ M G ++ +S+A L H P+Y K V+ F I + + G Sbjct: 119 RAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIA--PNLAAEG 176 Query: 561 VRVLTVCLGATDTALLTDEK 620 + V T+C G T+T +L D + Sbjct: 177 IAVHTICPGITETGVLGDRR 196 >UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 79.8 bits (188), Expect = 5e-14 Identities = 60/202 (29%), Positives = 101/202 (50%), Gaps = 8/202 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K+ +TG A+G+G + R L EG + + DI AG + ++EL G F R DV Sbjct: 6 KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 386 T E +L +L + G +DV++NNA + ++ +I + + + VN+ ++ Sbjct: 64 TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG-- 560 + +M + KGG++INVSS+ A+ V Y A+K+ V S + H ++ G Sbjct: 124 GLALMKQ----KGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVAL--HCAEKGYA 177 Query: 561 VRVLTVCLGATDTALLTDEKLG 626 +RV ++ G DT LL G Sbjct: 178 IRVNSLHPGYIDTPLLAGSNAG 199 >UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep: CylG - Streptococcus agalactiae Length = 240 Score = 79.8 bits (188), Expect = 5e-14 Identities = 53/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TG GIG ++ + L EG K IAI + + ++LQ EL K Y+ ++ Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386 +D + ++ + +E GGID ++NNA ++ D + + I +N+ L+ + Sbjct: 57 SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116 Query: 387 AIEIM-GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 ++IM K GK VIN+SS + + Y ATK A++ + + + F+ G+ Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGIAGQIGQANYSATKGAIISITKTLAK--EFASDGI 171 Query: 564 RVLTVCLGATDTALLTD 614 + V G +T + + Sbjct: 172 TINCVSPGFIETDMTNE 188 >UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=4; Sphingomonas|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 79.4 bits (187), Expect = 7e-14 Identities = 63/200 (31%), Positives = 98/200 (49%), Gaps = 6/200 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M++ KV ITG A+G+G + + +EG K + I D+ EE + + AE+ + G Sbjct: 1 MANRLAGKVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDA 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 365 F R DVTD + + A V GG+ + N A +++ +SI + K + VN TA Sbjct: 59 LFIRLDVTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTA 118 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 + AI + K SG G++IN+SS+ + + Y ATK+AV S Sbjct: 119 IFLGIKAAIPELVK-SG--NGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAAL--E 173 Query: 546 FSKTGVRVLTVCLGATDTAL 605 F GVRV T+ G +T + Sbjct: 174 FVDRGVRVNTIVPGGMNTPI 193 >UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All3753 protein - Anabaena sp. (strain PCC 7120) Length = 263 Score = 79.0 bits (186), Expect = 9e-14 Identities = 60/192 (31%), Positives = 93/192 (48%), Gaps = 6/192 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 + ITGAA+GIG +V I + ++ ++D A+E + + E K+G K D+ Sbjct: 7 QTALITGAASGIGYELVCIFAENDY-NLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDL 65 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDS-IGIYKKAIEVNVTALITSTLK 386 + I V Q +DV++NNA L ND+ + + ++VNV T Sbjct: 66 SKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKL 125 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 ++ M + GK ++NVSS AA +M +YFATK+ VL FS + TGV Sbjct: 126 FLKNMVQQGEGK---ILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALA--NELDGTGVT 180 Query: 567 VLTVCLGATDTA 602 V +C G T +A Sbjct: 181 VTVLCPGTTQSA 192 >UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase - Oceanobacillus iheyensis Length = 255 Score = 79.0 bits (186), Expect = 9e-14 Identities = 67/202 (33%), Positives = 100/202 (49%), Gaps = 13/202 (6%) Frame = +3 Query: 57 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 236 +TG A+G+GE+ VR L ++G K +AI D+ +E G+ L EL G+ +++ DVTDE Sbjct: 10 VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64 Query: 237 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 386 L+ V+++ GI V+N A A+ +IG + IE+N+ Sbjct: 65 SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124 Query: 387 AIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 A E M +S G+ G +IN +SVAA Y A+K V + I R S Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIAR--DLSTL 182 Query: 558 GVRVLTVCLGATDTALLTDEKL 623 G+RV+T+ G T L EKL Sbjct: 183 GIRVMTIAPGLFLTPLF--EKL 202 >UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyces|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 584 Score = 79.0 bits (186), Expect = 9e-14 Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 9/194 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS-D 221 ++V +TGA +GIG + + G + +A+ AE A ++ AE++ G + + D Sbjct: 317 QLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAART--AEMSRLIGAPDAWAETVD 374 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 383 V+DE+ + V E G +DV++NNA + + + ++K ++VN+ +I Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVI---- 430 Query: 384 KAIEIMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + GK G+GG ++N +S AA S +P Y +K+AVL S C+ R E + Sbjct: 431 HGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL-RAE-LAGQ 488 Query: 558 GVRVLTVCLGATDT 599 G+ V +C G T Sbjct: 489 GIGVSAICPGFVHT 502 >UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteria|Rep: Short-chain dehydrogenase - Symbiobacterium thermophilum Length = 254 Score = 79.0 bits (186), Expect = 9e-14 Identities = 61/194 (31%), Positives = 91/194 (46%), Gaps = 6/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITGAA G+G + + EG + + I D+ EE G++ QA G F R+DV Sbjct: 7 KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 404 + ++ V G +DV +NNAA D+ + E A+I LK + + Sbjct: 65 SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123 Query: 405 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 K+ G GG++IN+SSV+ + P Y A K V+ + +S G+R Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAM--DYSPHGIR 181 Query: 567 VLTVCLGATDTALL 608 V V GA DT +L Sbjct: 182 VNAVAPGAVDTPML 195 >UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR) family protein; n=1; Thermobifida fusca YX|Rep: Short-chain dehydrogenase/reductase (SDR) family protein - Thermobifida fusca (strain YX) Length = 282 Score = 79.0 bits (186), Expect = 9e-14 Identities = 57/194 (29%), Positives = 94/194 (48%), Gaps = 5/194 (2%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M+ + +V ITG A+GIGE+ VR EG + I DI EAG+ L EL G++ Sbjct: 1 MTQRLRGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRA 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383 F R+DV++E +++ V G +D+++NNA +M ++G + I L Sbjct: 56 VFVRTDVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNL 114 Query: 384 KAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 + + KH+ + G +I+ SS A + IY A K ++ SN + Sbjct: 115 RGVICGMKHAARVMKPRRSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVA--AEL 172 Query: 549 SKTGVRVLTVCLGA 590 + G+RV T+ G+ Sbjct: 173 RQHGIRVNTIIPGS 186 >UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 253 Score = 79.0 bits (186), Expect = 9e-14 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 KDKV +TG A+GIGE+ VR+ +G + I D G+ L EL S+ + Sbjct: 9 KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 377 DV+ E+ +++ V G +D+++ NA + + S + +++ I+VN+T + S Sbjct: 66 DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 AI M K G GG ++N++S+ Y A K V+ + +G H ++ Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLG-VSH-AQD 181 Query: 558 GVRVLTVCLGATDTALL 608 G+RV VC G T L+ Sbjct: 182 GIRVNAVCPGFVATPLI 198 >UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 270 Score = 79.0 bits (186), Expect = 9e-14 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 9/198 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K KV+ ITG ATGIG +V + + + + +D+ EEA +L ++L+++ G F Sbjct: 26 KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 377 D T + ++++ G +DV+INN A L D G ++ + VN+ + + Sbjct: 85 DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 AI +M + G +IN+SS+ L MP Y A KSA+ S + + + Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVLIGPKQMPGYVAAKSALNGLSKSLA--NQYGEY 198 Query: 558 GVRVLTVCLG--ATDTAL 605 G+RV T+ G ATD L Sbjct: 199 GIRVNTILPGWVATDRQL 216 >UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase SDR - Pelobacter propionicus (strain DSM 2379) Length = 283 Score = 79.0 bits (186), Expect = 9e-14 Identities = 57/206 (27%), Positives = 102/206 (49%), Gaps = 10/206 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITGA GIG ++ L +G + + D+ + + E+ ++ G K R+DV Sbjct: 24 KVAIITGAGRGIGRAIALRLGADGAAMV-VSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 383 T E +++ V++ G +D+++ NA + N + I + + + VN A + T+ Sbjct: 82 TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141 Query: 384 KAIEIMGK-HSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 A +++ + HS G GG +IN +S+AA + ++ Y A+K AV F+ + + K Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAKELGPYK 201 Query: 555 TGVRVLTVCLGATDTALLTDEKLGTF 632 V + TD L DEK+G + Sbjct: 202 INVNAYCPGIVGTDMWTLIDEKMGPY 227 >UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Comamonas testosteroni KF-1 Length = 259 Score = 79.0 bits (186), Expect = 9e-14 Identities = 59/191 (30%), Positives = 93/191 (48%), Gaps = 6/191 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 + ITGA GIG + + EG + + AE ++ +A L + G + +DV Sbjct: 9 RTALITGAGAGIGAAASHLFCKEGAAVLMVDANAEALERTREAILQAVPGARLACVMADV 68 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITSTLK 386 +DE + VQ+ GG+D ++NNAA+ N S A E VN+ + Sbjct: 69 SDESAAAAAVGQCVQQWGGLDTLVNNAAMRNYSAAADATAAEWQAMVGVNLVGMSNYCRA 128 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A+ + + SG G+++NVSS A+T M +Y ATK+A L ++ + E + GVR Sbjct: 129 ALPAL-RQSG--TGSIVNVSSCYAVTGRKGMALYDATKAAQLAYTRSLAFEE--AAHGVR 183 Query: 567 VLTVCLGATDT 599 VC G+T T Sbjct: 184 ANAVCPGSTLT 194 >UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 843 Score = 79.0 bits (186), Expect = 9e-14 Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 6/192 (3%) Frame = +3 Query: 51 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230 V +TGAA G G+ + + +I I DI E+ + E+ K G K FY+ DV+D Sbjct: 577 VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635 Query: 231 EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 392 E+ + + +Q+ ID++INN + N S +KA VN A ++ K + Sbjct: 636 EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 +M + + G ++NVSSVA+L S M Y A+K+A+ F N + K + Sbjct: 696 PVMIERNQGH---IVNVSSVASLMPSAKMTDYCASKAALSGFHNALRLELKQQKKNINTT 752 Query: 573 TVCLGATDTALL 608 +C A +T +L Sbjct: 753 LICPYAVNTGVL 764 >UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Bacillus halodurans|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 247 Score = 78.6 bits (185), Expect = 1e-13 Identities = 53/211 (25%), Positives = 101/211 (47%), Gaps = 10/211 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 +DKV +TGA GIG+ +V+ +++G I EA + ++ LN G K Y S Sbjct: 4 RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61 Query: 219 DVTDEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 377 D++ F+ + +VV + +D+++NNA + D +++ ++VN T Sbjct: 62 GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 A+ M + GK ++NV SV + Y A+K A++ + + R +S+ Sbjct: 122 CHAALPYMERKKQGK---IVNVVSVTGVVGREAQTNYGASKGAIIGLTRLLAR--KYSEK 176 Query: 558 GVRVLTVCLGATDTALL---TDEKLGTFDKY 641 G+ + + G +T ++ +EKL F ++ Sbjct: 177 GISINAIAPGMIETEMIKQVPEEKLKNFLRF 207 >UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 247 Score = 78.6 bits (185), Expect = 1e-13 Identities = 64/207 (30%), Positives = 102/207 (49%), Gaps = 7/207 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E +KVV ITG A+GIG + V L +G K + I D +E G++ EL G + F Sbjct: 3 ELTNKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFV 60 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALIT 374 ++DV++E ++ V+ +D++INNA M+ S Y+K ++V + Sbjct: 61 QTDVSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFL 120 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 + AI+ M K GG +IN SS+ ++ Q +P Y A K AV + + ++ Sbjct: 121 GSKHAIKEMIKTG---GGCIINTSSILGSVAQPEALP-YNAAKGAVNTMTKSLA--VEYA 174 Query: 552 KTGVRVLTVCLGATDTALLTDEKLGTF 632 +RV V G +TA + E LG F Sbjct: 175 DKQIRVNAVAPGFVETAAVNKEALGDF 201 >UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 262 Score = 78.6 bits (185), Expect = 1e-13 Identities = 58/210 (27%), Positives = 102/210 (48%), Gaps = 6/210 (2%) Frame = +3 Query: 18 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197 +K + +KV +TGAA GIG ++ + L+D G IA + EE Q Q + G+ Sbjct: 1 MKNATHLTNKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGD 55 Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNV 359 K DVTDE + I++A +++ ID+++NNA ++ ++K I++N+ Sbjct: 56 KVTPMTHDVTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINI 115 Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539 T I M K +G G ++N+SS +++ ++ Y A+K AV + Sbjct: 116 TGTFLGLHSVIPCM-KKAG--SGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAAL- 171 Query: 540 EHFSKTGVRVLTVCLGATDTALLTDEKLGT 629 G+RV +V GA +T + + L + Sbjct: 172 -ELGPFGIRVNSVHPGAVNTPMTNPQGLSS 200 >UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Leeuwenhoekiella blandensis MED217 Length = 257 Score = 78.6 bits (185), Expect = 1e-13 Identities = 47/167 (28%), Positives = 87/167 (52%), Gaps = 6/167 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K+KV +TG A+G+G+S ++L EG K I + DI EE G+ + ++ G + F + Sbjct: 5 KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKVVQQIKED-GGEAIFIKQ 62 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 380 DV E+ + ++ ++ G + ++ N+A + + D ++ +K I++N+ T Sbjct: 63 DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 521 I+ G +GG++IN SS+ L +P Y A+K V F+ Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFT 167 >UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep: Short chain dehydrogenase - Mycobacterium avium (strain 104) Length = 594 Score = 78.6 bits (185), Expect = 1e-13 Identities = 57/195 (29%), Positives = 93/195 (47%), Gaps = 6/195 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E + ++ +TGA GIG + L +G + + I+D + A A+ G Y Sbjct: 322 EVRGRLALVTGAGAGIGRATAVELARQGARKVVIVD-RDRAAADQTADAVRAAGAGAAVY 380 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392 + DV+DE + V E G +D+++NNA + G + + N A++ ++ + Sbjct: 381 QVDVSDEAAMNDLAAQVRNEHGVVDILVNNAGI--GMAGRFLETSPANWDAIMGVNVRGV 438 Query: 393 EIMGKHSG------GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 + G G+GGT+INV+S AA S M Y TK+AVL S + R + F+ Sbjct: 439 IWGSRAFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESL-RAD-FAD 496 Query: 555 TGVRVLTVCLGATDT 599 G+ V VC G +T Sbjct: 497 EGITVTAVCPGFVNT 511 >UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=4; Shewanella|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella sp. (strain ANA-3) Length = 292 Score = 78.6 bits (185), Expect = 1e-13 Identities = 54/200 (27%), Positives = 98/200 (49%), Gaps = 7/200 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GQSLQAELNSKYGNKTKFYR 215 K KV ITG+ +GIG + +L ++G H+ + + EA G+ L AE +Y T F Sbjct: 35 KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 377 +D+ D E ++A V+ G ID+++NNA + + I + I +N+++ + Sbjct: 94 ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 +A+ M + + G +IN++SV L S Y A K ++ + + ++ Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVA--IECAEQ 208 Query: 558 GVRVLTVCLGATDTALLTDE 617 G+ V +C G DT L+ + Sbjct: 209 GITVNAICPGWVDTPLINKQ 228 >UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2; Euryarchaeota|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 78.6 bits (185), Expect = 1e-13 Identities = 59/206 (28%), Positives = 95/206 (46%), Gaps = 7/206 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K KV ITGA GIG+S+ + +EG I I E Q + E+NS G+ + Sbjct: 4 KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERLEQ-ITNEINSNGGDASACI-G 61 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 377 DVT +E ++ + + G ID+++NNA +M+D + + + K I+VN+T + Sbjct: 62 DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 I M K++ GG +I +SSV L Y A+K V+ + + K Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV--YGKH 176 Query: 558 GVRVLTVCLGATDTALLTDEKLGTFD 635 +R + G +T + T G D Sbjct: 177 NIRSNVIAPGTVNTEIATTINPGRMD 202 >UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419; n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase SSP0419 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 234 Score = 78.6 bits (185), Expect = 1e-13 Identities = 59/209 (28%), Positives = 104/209 (49%), Gaps = 7/209 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGQSLQAELNSKYGNKTKF 209 E +DKV +TGA++GIG S+ L ++GVK + D + A + + + N + +T Sbjct: 3 ELQDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSI 62 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALI 371 DVT +E ++ ++ G ID+++N+A LM S + ++ I+VN+ + Sbjct: 63 V--DVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTL 120 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 + + M S G +IN++S++ + +Y A+K+AV + G + + Sbjct: 121 YTINAVLPSMLNQSSGH---IINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKELA 175 Query: 552 KTGVRVLTVCLGATDTALLTDEKLGTFDK 638 KTGVRV ++ G DT L D G K Sbjct: 176 KTGVRVTSISPGMVDTPLSGDTDWGARKK 204 >UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=7; Eukaryota|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Gallus gallus (Chicken) Length = 255 Score = 78.6 bits (185), Expect = 1e-13 Identities = 57/197 (28%), Positives = 97/197 (49%), Gaps = 9/197 (4%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSK-YGNKTKFY 212 W +V +TGA+ GIG +V R L+ G+K + ++ + L AE S Y Y Sbjct: 4 WTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKI-EKLAAECQSAGYPGTLIPY 62 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 374 + D+++EE L + +A+ G+DV INNA L++ ++ I+VNV A+ Sbjct: 63 KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSI 122 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSV--AALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 T +A + M K G +IN++S+ ++ V+ Y ATK AV + + + Sbjct: 123 CTREAYQSM-KERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELRE 181 Query: 549 SKTGVRVLTVCLGATDT 599 +KT +R + G +T Sbjct: 182 AKTHIRATCISPGLVET 198 >UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain type dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 252 Score = 78.2 bits (184), Expect = 2e-13 Identities = 63/199 (31%), Positives = 93/199 (46%), Gaps = 6/199 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M+ K + ITGA IG+ R + EG + + I DIAEEAG+++ AEL G Sbjct: 1 MAGRLSGKRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAA 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383 F + DVT E ++ V+ GG+D + NA L G + N AL Sbjct: 56 HFVQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNA 113 Query: 384 KAIEIMGKHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 +A KH+ GK G++IN+SS+A + Y A+K AV+ F+ + Sbjct: 114 RAHFFGAKHAIPHLQRSGK-GSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALAL--E 170 Query: 546 FSKTGVRVLTVCLGATDTA 602 + +RV +C G DTA Sbjct: 171 LAPDNIRVNAICPGWVDTA 189 >UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 257 Score = 78.2 bits (184), Expect = 2e-13 Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 5/192 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS-D 221 KV +TGAA G+GE++ L +G + +A+LD+ +E G + + GN +YR+ D Sbjct: 7 KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGNA--YYRNCD 63 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 392 + D E ++ V G +DV++NNAA+ I + + E N+ + S++ Sbjct: 64 IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123 Query: 393 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 ++ + GG VIN+SSV Y ATK A++ S + + + +RV Sbjct: 124 RFVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLA--AEWGRFNIRV 181 Query: 570 LTVCLGATDTAL 605 TV GA D + Sbjct: 182 NTVSPGAIDATM 193 >UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019; n=11; cellular organisms|Rep: Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima Length = 256 Score = 78.2 bits (184), Expect = 2e-13 Identities = 53/192 (27%), Positives = 96/192 (50%), Gaps = 6/192 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TG GIG ++ ++ + G+K + I +I EEAG + L + G F ++DV Sbjct: 5 KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 386 DE ++ V+ GG+DV++NNAA+M+ + +++ I VN+T + Sbjct: 63 ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 E M K GG +IN++S A Y A+K ++ ++ + S+ +R Sbjct: 123 CAEEMIKRG---GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA--VSLSRYHIR 177 Query: 567 VLTVCLGATDTA 602 V+++ G +T+ Sbjct: 178 VVSISPGWIETS 189 >UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 257 Score = 77.8 bits (183), Expect = 2e-13 Identities = 59/199 (29%), Positives = 106/199 (53%), Gaps = 7/199 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 +++DKV+ +TGAA GIG+ VVR + + K + ++D+ E+A +S+QAEL N + Sbjct: 3 KFQDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVV 60 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 371 ++DV++EE+ ++ + + G ID +NNA + + I + +NV ++ Sbjct: 61 KADVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVL 120 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 + +M K G+++N +SVA L S M +Y ++K AV+ N + E + Sbjct: 121 FGLKYVLPVM---KAQKSGSIVNTASVAGLIGSPSMALYNSSKHAVMGL-NKVAALES-A 175 Query: 552 KTGVRVLTVCLGATDTALL 608 VRV TV G +T ++ Sbjct: 176 AFNVRVNTVNPGVINTQMM 194 >UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=6; Desulfuromonadales|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Geobacter sulfurreducens Length = 246 Score = 77.8 bits (183), Expect = 2e-13 Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 5/214 (2%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E+KD +V +TG GIG ++ +G A +EA ++L+AE G+ Sbjct: 2 EFKDSIVVVTGGTRGIGRAISLHFARQGALVTAAYRADDEAARALEAEAAGLPGS-IAVI 60 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392 R+DV E + +++A E G + V++NNA ++ D G E + A++ + L + Sbjct: 61 RADVGTAEGAMAVIDAASGESGTLHVLVNNAGIIRD--GYLAMMAEDDWDAVMRANLSPL 118 Query: 393 EI-----MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + K + G +IN+SSV+A + Y ATK A + F+ + R Sbjct: 119 FHCCKWGVRKMLARRRGAIINLSSVSAFAGTAGQTNYAATKGAAVSFTKSLAR--EVGPL 176 Query: 558 GVRVLTVCLGATDTALLTDEKLGTFDKYLXSSCL 659 G+RV V G +T ++ K D+ + SS L Sbjct: 177 GIRVNAVAPGLIETEMIAGMKREMVDRIVGSSIL 210 >UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Staphylococcus epidermidis|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 255 Score = 77.8 bits (183), Expect = 2e-13 Identities = 54/188 (28%), Positives = 100/188 (53%), Gaps = 7/188 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV + G ATGIG+++ L G +I I D+ GQ ++++ G KT + D+ Sbjct: 13 KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 392 T + I++ VV+E G ID+++NNA ++ +D+ I Y++ + E+N++ + Sbjct: 72 THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129 Query: 393 EIMGKHSGGKG-GTVINVSSVAAL--TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 + +G+ KG G++INVSSV L ++ Y +K+ V + + R +S+ G+ Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLAR--EWSRYGI 187 Query: 564 RVLTVCLG 587 +V + G Sbjct: 188 KVNAIAPG 195 >UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3; Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase - Eubacterium sp. (strain VPI 12708) Length = 266 Score = 77.8 bits (183), Expect = 2e-13 Identities = 52/211 (24%), Positives = 105/211 (49%), Gaps = 10/211 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 KDKV+ +T + GIG ++ + EG K ++ ++ E ++ E+N+ GN K+ Sbjct: 4 KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 368 +D T EE ++ ++ +++++G IDV++NN + N ++ K + +N+ ++ Sbjct: 61 NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120 Query: 369 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 ++ A++ M ++ GG++IN+SSV L Y +K+A+ + I H Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIA--VHE 175 Query: 549 SKTGVRVLTVCLGATDTALLTDEKLGTFDKY 641 ++ +R V G T T + D F + Sbjct: 176 ARHNIRCNAVLPGMTATDAVQDNLTDDFRNF 206 >UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 254 Score = 77.8 bits (183), Expect = 2e-13 Identities = 54/195 (27%), Positives = 96/195 (49%), Gaps = 6/195 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 ++KV ITG TGIG+ + EG K I I DI E++G +++ + +G + F Sbjct: 7 ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 380 DV++E+ + + + + +D++ NNA L + + + + +NVT + Sbjct: 65 DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + +M K + G+VIN SS+A LT + +Y A+K AV + ++ G Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLTGAAGHVLYGASKGAVRIMTK--DAAMEYAPYG 179 Query: 561 VRVLTVCLGATDTAL 605 VRV ++ G DT + Sbjct: 180 VRVNSIHPGYIDTGM 194 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 77.8 bits (183), Expect = 2e-13 Identities = 60/194 (30%), Positives = 94/194 (48%), Gaps = 6/194 (3%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 ++ KVV ITGA +GIG+ + + G K +AI DI+EE G+ EL G + F Sbjct: 3 FQGKVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIF 60 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITS 377 DV + I+ V+ G +D+++NNA ++ S + K + VNV Sbjct: 61 GDVAKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + A+E M K GG ++NVSS A L +Y +K+A+L + + + Sbjct: 119 SKYAVEQMKKQG---GGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLA--VDYVDY 173 Query: 558 GVRVLTVCLGATDT 599 G+RV VC G T + Sbjct: 174 GIRVNAVCPGTTQS 187 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 77.4 bits (182), Expect = 3e-13 Identities = 53/199 (26%), Positives = 101/199 (50%), Gaps = 7/199 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197 MS +++ KV +TGAA+ G+G ++ + EG I ++D+ +E + A++ ++G Sbjct: 5 MSKQFEGKVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGV 63 Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 377 KT +VT E ++ V ++ G +D ++NNA ++ D++ I + E ++ Sbjct: 64 KTLGLSCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDV 121 Query: 378 TLKAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542 LK + +M K++ + G ++N+SSV+ LT Y ++K+ V+ + R Sbjct: 122 NLKGVFLMTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR-- 179 Query: 543 HFSKTGVRVLTVCLGATDT 599 F+ V V VC G T Sbjct: 180 EFAGRNVLVNAVCPGYVQT 198 >UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR; n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 595 Score = 77.4 bits (182), Expect = 3e-13 Identities = 60/201 (29%), Positives = 93/201 (46%), Gaps = 7/201 (3%) Frame = +3 Query: 27 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGQSLQAELNSKYGNKT 203 S + KV +TGA +GIG EG +A +D+A +L L G + Sbjct: 322 SGRFSGKVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAERTALLIGLT---GAQA 378 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTA 365 R DV + + V GG DVVINNA + ++ S +++ + VN+ Sbjct: 379 HAKRVDVGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWG 438 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 +I + + M G GG ++N +S AA S +P Y TK+AVL S C+ R E Sbjct: 439 VIHGSRLFAQQMAAR--GTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM-RAE- 494 Query: 546 FSKTGVRVLTVCLGATDTALL 608 ++ G+ V VC G +T ++ Sbjct: 495 LAEQGIGVTAVCPGFAETGIM 515 >UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short-chain dehydrogenase/reductase - marine gamma proteobacterium HTCC2143 Length = 264 Score = 77.4 bits (182), Expect = 3e-13 Identities = 60/200 (30%), Positives = 101/200 (50%), Gaps = 6/200 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M++ + KV ITG +GIGE+ I + EG + + +EE GQ++ L G+K Sbjct: 1 MTNRLQGKVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIANRL----GDKA 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTA 365 + ++DV+ EE ++ V+ G +DV+ NNA DSI G +++ +++ Sbjct: 56 HYIKADVSKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSS 115 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 ++ AIE M K +G GG +IN +S+AA+ +Y A K+AV ++ G Sbjct: 116 VVLGIRYAIEPM-KANG--GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAG--VE 170 Query: 546 FSKTGVRVLTVCLGATDTAL 605 G+RV + GA T + Sbjct: 171 LGPLGIRVNCISPGAIATPI 190 >UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyces coelicolor|Rep: Putative dehydrogenase - Streptomyces coelicolor Length = 276 Score = 77.0 bits (181), Expect = 4e-13 Identities = 54/197 (27%), Positives = 99/197 (50%), Gaps = 7/197 (3%) Frame = +3 Query: 30 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 209 HE+ + +TGA+ G+GE+ R L G H+ ++ + +A +L E+ + + + Sbjct: 2 HEYTNTTALVTGASKGLGEAYARELASRGA-HLVLVARSADALHALADEIRATHSVRVDV 60 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 371 +D++D +L+AV +D+++NNA + + + ++++VNVTAL+ Sbjct: 61 IAADLSDRRSPQRVLDAVDGLGLDVDLLVNNAGMGAVGPFLVRPLAPNLQSVDVNVTALV 120 Query: 372 TSTLKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 + ++G +G G ++N++S AA Y ATK+ VL F+ + E Sbjct: 121 ----GLVHLLGARMVERGRGGIVNIASTAAFQPMPYQASYAATKAFVLSFTEAVA--EEV 174 Query: 549 SKTGVRVLTVCLGATDT 599 TGVRV+ GAT T Sbjct: 175 RGTGVRVMAAHPGATAT 191 >UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 261 Score = 77.0 bits (181), Expect = 4e-13 Identities = 61/196 (31%), Positives = 94/196 (47%), Gaps = 7/196 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 +D+VV ITG GIG ++ R + EG I+ +E A+ + G + Sbjct: 28 EDQVVLITGGNRGIGLAMARAVAKEGAS--VIITGRDEHTLHHAADQIKRDGGTVVSHVC 85 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 377 DV DE+ + A+ + IDV++NNA L S+ ++ IE N+T Sbjct: 86 DVRDEDSVDELFAAIHRHYSQIDVLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLC 145 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 T A+ +M G TV+N SVAA T M Y A+K+ +L F+N + E Sbjct: 146 TRAALPMMSP-----GATVVNNVSVAANTAFPGMAAYSASKAGLLAFTNTL--REELRPR 198 Query: 558 GVRVLTVCLGATDTAL 605 G+RV+++ GATDT + Sbjct: 199 GIRVISLVPGATDTEI 214 >UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 252 Score = 77.0 bits (181), Expect = 4e-13 Identities = 59/191 (30%), Positives = 89/191 (46%), Gaps = 6/191 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITG ATGIG + + EG + I DI EE G S E G F R DV Sbjct: 7 KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386 + EE ++ A +E G +DVV NA L+ S ++ + +N+TA T Sbjct: 65 SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A +M +H +GG++I ++S L + Y A+K ++ + + + + +R Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLA--DELAPHNIR 179 Query: 567 VLTVCLGATDT 599 V VC G DT Sbjct: 180 VNCVCPGWVDT 190 >UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Clostridium perfringens|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 272 Score = 77.0 bits (181), Expect = 4e-13 Identities = 56/197 (28%), Positives = 98/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 + DKV+ ITGAA GIG++V EG K + + D EE + E+ N +F Sbjct: 9 FSDKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLI 66 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALIT 374 D+ + E+ +++ +++ GG+D++INNA + S +++ ++ N+ Sbjct: 67 CDLREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFH 126 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 + I+ M K + KGG ++NVSSVA LT Y +K + + + +++ Sbjct: 127 CSHYGIQEMIKQN--KGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMAL--DYAR 182 Query: 555 TGVRVLTVCLGATDTAL 605 G+RV V G TDT + Sbjct: 183 YGIRVNAVNPGTTDTPM 199 >UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR; n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 246 Score = 77.0 bits (181), Expect = 4e-13 Identities = 56/193 (29%), Positives = 93/193 (48%), Gaps = 6/193 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K+ +TGA GIG+++ L EG + + D+ +A + A L+ + +DV Sbjct: 7 KIAVVTGAGQGIGKAIATKLAAEGAT-VVVTDVDHQAAKETAAALD----HGAIGLHADV 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 386 TD +++ VV G IDV++NNA A ++ + + I +N+ ++ ++ K Sbjct: 62 TDRTSVDAMVDEVVATFGRIDVLVNNAGWDKGEAFVDSEPETWDRIIGINLYGVLNTSKK 121 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 + IM G+V+N+ S A S +Y A K V+ FS R +++ V Sbjct: 122 VLPIMAAQG---SGSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAR--EMARSQVN 176 Query: 567 VLTVCLGATDTAL 605 V VC G TDTAL Sbjct: 177 VNCVCPGPTDTAL 189 >UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Chlorobium/Pelodictyon group|Rep: Short-chain dehydrogenase/reductase SDR precursor - Chlorobium phaeobacteroides (strain DSM 266) Length = 280 Score = 77.0 bits (181), Expect = 4e-13 Identities = 58/199 (29%), Positives = 99/199 (49%), Gaps = 6/199 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K +TGAA+GIG ++ L++ G + + + DI + A L + T DV Sbjct: 8 KNAIVTGAASGIGFALAVGLIERGAR-VWVADIDSAGVERAAASLGAGAHPVTL----DV 62 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386 D F ++ V ++ GGID + NNA +++ + I+VN+ ++ TL Sbjct: 63 RDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTLA 122 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A +M + + G ++N +S+A L + ++ Y TK AV+ FS+ + R E + GVR Sbjct: 123 AYPLMVRQ---RSGHIVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL-RFE-AERYGVR 177 Query: 567 VLTVCLGATDTALLTDEKL 623 V +C DT LL +E + Sbjct: 178 VSAICPAGVDTPLLDEEAI 196 >UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Delftia acidovorans SPH-1|Rep: Short-chain dehydrogenase/reductase SDR - Delftia acidovorans SPH-1 Length = 301 Score = 77.0 bits (181), Expect = 4e-13 Identities = 60/201 (29%), Positives = 97/201 (48%), Gaps = 6/201 (2%) Frame = +3 Query: 18 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197 +K ++ K V +TGA+ GIGE R L G K + ++ + + + L +EL Sbjct: 42 MKTPFDFSQKTVLVTGASMGIGEVFARELARRGAK-VVLIARSRDRLEKLASELPG---- 96 Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNV 359 +F D+ + +AV D+++NNA ++ + ++ I++NV Sbjct: 97 -AEFLVEDLATPGAARRVFDAVSARGLLPDLLVNNAGFGTHGRFDELALDMQRETIDLNV 155 Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539 AL+ T + + + GG VIN++S AA M +Y ATK+ VL FS + Sbjct: 156 GALVELTHLCLPALEQRQGG----VINIASTAAFQPVPYMAVYAATKAFVLSFSEALW-- 209 Query: 540 EHFSKTGVRVLTVCLGATDTA 602 + GVRVL +C GATDTA Sbjct: 210 AEYRPRGVRVLALCPGATDTA 230 >UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular organisms|Rep: Os07g0664000 protein - Oryza sativa subsp. japonica (Rice) Length = 572 Score = 77.0 bits (181), Expect = 4e-13 Identities = 62/210 (29%), Positives = 94/210 (44%), Gaps = 10/210 (4%) Frame = +3 Query: 9 YGTLKMSHE-WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS 185 + T SH+ KV ITG A+GIG++ + G K + I DI ++ G S+ AEL Sbjct: 301 FSTASSSHQRLAGKVAVITGGASGIGKATATEFIKNGAK-VIIADIQDDLGHSVAAEL-- 357 Query: 186 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA----ALMND-----SIGIYK 338 G + R DV DE + V+ G +DV NNA AL D +G + Sbjct: 358 --GPDAAYTRCDVADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFD 415 Query: 339 KAIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQF 518 + + VN + + + A M G V+ SS A + +P+Y +K+ V+ Sbjct: 416 RVMAVNARSTLAAVKHAARAMAPRC---SGCVLCTSSGAGVIPVPAVPVYSVSKATVIAI 472 Query: 519 SNCIGRPEHFSKTGVRVLTVCLGATDTALL 608 P ++ G+RV + GAT T LL Sbjct: 473 VRAAAEP--MARHGLRVNAISPGATRTPLL 500 >UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Methanoregula boonei 6A8|Rep: Short-chain dehydrogenase/reductase SDR - Methanoregula boonei (strain 6A8) Length = 253 Score = 77.0 bits (181), Expect = 4e-13 Identities = 53/198 (26%), Positives = 94/198 (47%), Gaps = 6/198 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV+ +TGA+ GIG + + + I + +SL +E+ + G+ R+DV Sbjct: 12 KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 386 T EE + + ++ G +D+++NNA +M ++ I Y+ ++VN T Sbjct: 71 TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A +IM + K GT+IN++SV + + Y ++KS V+ F+ C + + Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAK--ELGAFNIT 185 Query: 567 VLTVCLGATDTALLTDEK 620 V V G DT L D + Sbjct: 186 VNAVAPGFIDTDLTADTR 203 >UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 253 Score = 77.0 bits (181), Expect = 4e-13 Identities = 51/173 (29%), Positives = 95/173 (54%), Gaps = 10/173 (5%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 DKV +TGA++ IG+ + + ++EG K I I E ++ + E+ ++ + T D Sbjct: 5 DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 380 + DE L ++N ++ G ID+++NNA +ND I + +K I VN+ + T Sbjct: 62 LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVA---ALTQSHVMPIYFATKSAVLQFSNCI 530 KA ++ K + K G+++N+ S++ A+ + H + +Y ATK+A+ F+ I Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISSERAIPRVH-LAVYSATKAAIPMFTKSI 170 >UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Thermotoga|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima Length = 257 Score = 76.6 bits (180), Expect = 5e-13 Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 8/198 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K KV +TG GIG+++ + L G + I+DI EE + E+ K G + FY Sbjct: 11 KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 380 DVT EE G + + G +D+ +NNA + N + +KK I+VN+ + S Sbjct: 69 DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 M + GK +IN++S++ + + Y A+K+ V+ + + ++ Sbjct: 129 KAEFHAMKERKYGK---IINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA--AEWAP 183 Query: 555 TGVRVLTVCLGATDTALL 608 G+RV ++ G T L+ Sbjct: 184 YGIRVNSISPGYIRTPLI 201 >UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular organisms|Rep: Alcohol dehydrogenase - Bordetella parapertussis Length = 252 Score = 76.6 bits (180), Expect = 5e-13 Identities = 55/195 (28%), Positives = 91/195 (46%), Gaps = 5/195 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K +TGA +G GE + EG K + + DI E GQ + A +N+ G + F R+DV Sbjct: 6 KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 404 +D +L A ++ GG+D+V+NNA + + + + E + +K+I + Sbjct: 64 SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122 Query: 405 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 +H GG+ IN++S AA+ + Y +K AV+ S + V Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNC 182 Query: 570 LTVCLGATDTALLTD 614 + +GA T LL D Sbjct: 183 VNPVIGA--TGLLAD 195 >UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 247 Score = 76.6 bits (180), Expect = 5e-13 Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 6/203 (2%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M H+ D+VV +TGA GIG+S+V G ++A +DI + + ELN+ Sbjct: 1 MKHQ--DQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNI 57 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365 +++ + + AVV++ G +D +IN A A ++ + K I VN+T Sbjct: 58 VAITANIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTG 117 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 +A ++M G +INVSS AALT Y A+K+ V+ + + R Sbjct: 118 TFLCCREAAKVMQAQG---SGCIINVSSTAALT-GEGPSHYCASKAGVMGLTRSMAR--E 171 Query: 546 FSKTGVRVLTVCLGATDTALLTD 614 + G+RV T+ G T+T ++ D Sbjct: 172 LAPVGIRVNTIVPGPTNTPMMAD 194 >UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 76.6 bits (180), Expect = 5e-13 Identities = 48/164 (29%), Positives = 83/164 (50%), Gaps = 7/164 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 + KV ITG A GIG R L G +AILD+ + ++L E+ ++ G + F+ Sbjct: 11 RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 377 DVT E + +V G +DV++NNA + ++ +++ ++VNV + Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 509 T AI + GG+++N+SS+ + +P Y A+K+AV Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAV 169 >UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legionella pneumophila|Rep: Acetyoacetyl CoA reductase - Legionella pneumophila (strain Corby) Length = 248 Score = 76.6 bits (180), Expect = 5e-13 Identities = 54/196 (27%), Positives = 93/196 (47%), Gaps = 7/196 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGQSLQAELNSKYGNKTKFYRS 218 + VV ITG IG +V + LD KH+ LD+ + G+ +L ++ F Sbjct: 4 NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 380 DVTD E ++ +++E GGIDV+INNA + D++ + + + VN+ + T Sbjct: 63 DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + +E M G+ ++NVSSV A Y A+K+ V F+ + + Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNAQKGQFSQANYAASKAGVYGFTKSLA--QELMIKN 177 Query: 561 VRVLTVCLGATDTALL 608 + V ++ G +T L+ Sbjct: 178 ITVNSISPGYVNTRLM 193 >UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Probable glucose 1-dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 268 Score = 76.6 bits (180), Expect = 5e-13 Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 5/198 (2%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K K V +TG + GIG + R L G + + E++ Q L E+++ YG +T + Sbjct: 7 KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398 DV+ E + + GGID+++NNA +SI +E +I LK + Sbjct: 67 DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124 Query: 399 MGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 K +G + GG +IN+SS+ + + Y + K+ + S C+ ++ + Sbjct: 125 CSKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSL--ELAENNI 182 Query: 564 RVLTVCLGATDTALLTDE 617 RV++V GA T + DE Sbjct: 183 RVVSVAPGAISTEMNRDE 200 >UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specificities; n=2; Pezizomycotina|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 271 Score = 76.6 bits (180), Expect = 5e-13 Identities = 59/215 (27%), Positives = 102/215 (47%), Gaps = 23/215 (10%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN------KTKF 209 + ITGAA+GIG + +G IA+LD+ + A +++QAE+NS+ + + Sbjct: 6 IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTARCRVEI 65 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-------YKKAIEVNVTA 365 Y +VTDE ++N+ Q +D V+N A + M G +++ ++VN+T Sbjct: 66 YPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRILDVNLTG 125 Query: 366 LITSTLKAIEIMGKHS------GGK---GGTVINVSSVAALTQSHVMPIYFATKSAVLQF 518 A IM G+ G+++N SS+ + + Y ATK AV+ Sbjct: 126 TFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATKHAVIGL 185 Query: 519 SNCIGRPEHFSKTGVRVLTVCLGATDTALLTDEKL 623 + E ++K G+R+ +C G T+T + T L Sbjct: 186 TRTAS--EDYAKDGLRINAICPGYTETPMTTKSPL 218 >UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 249 Score = 76.2 bits (179), Expect = 7e-13 Identities = 58/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K+ +TGA++GIG + L + G K + I + + L+ ++ +K G + DV Sbjct: 7 KIALVTGASSGIGAATAAKLAEAGAK-VGIAARRTDKLEDLKKKIEAK-GGEALVIEMDV 64 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM--ND----SIGIYKKAIEVNVTALITSTLK 386 D + +V G ID+++NNA LM +D + +++ ++VNV L+ +T Sbjct: 65 VDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAA 124 Query: 387 AI-EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 + +++ +HS G V N+SS+A + +Y ATK AV FS+ + R E K G+ Sbjct: 125 VLPQMIKQHS----GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGL-RMEVGQKHGI 179 Query: 564 RVLTVCLGATDTAL 605 RV + GA T L Sbjct: 180 RVTCIQPGAVATEL 193 >UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Chromobacterium violaceum Length = 246 Score = 76.2 bits (179), Expect = 7e-13 Identities = 55/196 (28%), Positives = 95/196 (48%), Gaps = 6/196 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K KV ITG+A+GIG++ + EG +A+ D+ +A +++ EL + G + Y+ Sbjct: 4 KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 380 DVTD+ ++ + G IDV++NNA ++ D+ I + K I++N+ + Sbjct: 62 DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 ++ M + GG ++N SSV + + Y A K V+ F + K G Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAK--ELGKKG 176 Query: 561 VRVLTVCLGATDTALL 608 +R VC G T +L Sbjct: 177 IRANAVCPGFVATPIL 192 >UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Photobacterium profundum|Rep: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 255 Score = 76.2 bits (179), Expect = 7e-13 Identities = 55/194 (28%), Positives = 89/194 (45%), Gaps = 7/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV I+G +GIGE+ R+ +G + ++ E GQ L ELN++Y T F ++D+ Sbjct: 10 KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 383 T + + E GGID NNA + S I+ + I N+ Sbjct: 67 TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 + + IM K GT++N++S+ ++ Y ++ AVL + ++K GV Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTR--SAAVEYAKQGV 181 Query: 564 RVLTVCLGATDTAL 605 RV V GA DT + Sbjct: 182 RVNAVAPGAIDTPI 195 >UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 257 Score = 76.2 bits (179), Expect = 7e-13 Identities = 54/199 (27%), Positives = 104/199 (52%), Gaps = 8/199 (4%) Frame = +3 Query: 15 TLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG 194 T+ + K +TG A G+G ++ + L G IAI+DI EA E+ + Y Sbjct: 2 TVSTIFDLSTKHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYS 60 Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVN 356 T+ ++DV+ EE +++ V++ IDV++NNA ++ D++ + +K+ ++VN Sbjct: 61 VNTQSIQADVSKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVN 120 Query: 357 VTALITSTLKAIEIMGKHSGGKG-GTVINVSSVAA-LTQSHVMPIYFATKSAVLQFSNCI 530 + AL ++ + +GKH G G+++N+SS++A + Y A+K AV + + Sbjct: 121 INALFLTSKQ----VGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSL 176 Query: 531 GRPEHFSKTGVRVLTVCLG 587 +++ G+RV + G Sbjct: 177 A--SEWAQYGIRVNAIAPG 193 >UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; Frankia|Rep: Short-chain dehydrogenase/reductase SDR precursor - Frankia sp. (strain CcI3) Length = 291 Score = 76.2 bits (179), Expect = 7e-13 Identities = 58/195 (29%), Positives = 92/195 (47%), Gaps = 4/195 (2%) Frame = +3 Query: 57 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 236 ITGA++GIG + D G + + + +E + L ++YG + D+ DE Sbjct: 14 ITGASSGIGAAFAEAYADRGARLVLVAP-SEPRLWMVAERLGARYGTEAHVIAVDLADER 72 Query: 237 HFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNVTALITSTLKAIEIMG 404 + AV + +D+++NNA + + EV + + + + + G Sbjct: 73 GPDRLAEAVAEAGLEVDILVNNAGFGTRGPYHELSADRDHREVMLNVVAVERVAHLFLPG 132 Query: 405 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCL 584 + G+G TVINVSS + M +Y A+K+ VL FS IG + + GVRVL +C Sbjct: 133 MVARGRG-TVINVSSTSGFQAVPYMTVYGASKAFVLSFS--IGLWAEYRRRGVRVLALCP 189 Query: 585 GATDTALLTDEKLGT 629 G TDT E LGT Sbjct: 190 GPTDTEFF--EVLGT 202 >UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 271 Score = 76.2 bits (179), Expect = 7e-13 Identities = 57/199 (28%), Positives = 93/199 (46%), Gaps = 4/199 (2%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M + KV +TG A GIGE+ R + G +AILD E+AG A + + +G + Sbjct: 1 MKIDLSGKVAVVTGGAMGIGEACARKIALAGAS-VAILDPNEDAGTKTAAAIRA-HGGEC 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383 KF+R DV+ + + V+ + ID++++NA + G E + +I L Sbjct: 59 KFFRCDVSKSKDVEQAVGDVITKHSQIDILVSNAGI--QYYGDVITTPEDDWDRVIGVNL 116 Query: 384 KAIEIMGK----HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 K ++ K H GG ++ + SV + T Y +K AVL + + ++ Sbjct: 117 KGCFLISKFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMAL--DYA 174 Query: 552 KTGVRVLTVCLGATDTALL 608 G+RV VC G DT +L Sbjct: 175 HKGIRVNCVCPGTIDTPML 193 >UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4; Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase - Clostridium perfringens (strain SM101 / Type A) Length = 253 Score = 76.2 bits (179), Expect = 7e-13 Identities = 65/210 (30%), Positives = 99/210 (47%), Gaps = 10/210 (4%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 +S K+KVV +TG GIG + V+ LD G K +A+ +E ELN N Sbjct: 4 LSKSIKNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYD 62 Query: 204 KF-YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNV 359 + ++ D +++ V+++ G ID++INNA ++D+ IY K I++NV Sbjct: 63 AIGFYPNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINV 121 Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539 A+ T EIM K G ++N SSV +L Y +K AV + + R Sbjct: 122 KAIFNCTKAVSEIM---KNKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLAR- 177 Query: 540 EHFSKTGVRVLTVCLG--ATDTALLTDEKL 623 + G+RV V G ATD D+KL Sbjct: 178 -ELGRDGIRVNAVAPGIIATDMVAALDKKL 206 >UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteobacteria|Rep: Short chain dehydrogenase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 278 Score = 76.2 bits (179), Expect = 7e-13 Identities = 64/205 (31%), Positives = 92/205 (44%), Gaps = 7/205 (3%) Frame = +3 Query: 15 TLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG 194 T + S+E V ITGA TGIG + EG + +A+ EEAG +L AEL + G Sbjct: 23 TNQRSNEMNTPTVLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LG 80 Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEV 353 N+ +F +DV E ++ V G IDV +NNA ++ S Y + V Sbjct: 81 NEAEFLLADVRFEADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGV 140 Query: 354 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533 NV + S + +M G++IN+SSVA +Y A+K AV + Sbjct: 141 NVLGTMLSLKHEMRVMLAQG---SGSIINLSSVAGKVGIAGASVYVASKHAVEGLTKSAA 197 Query: 534 RPEHFSKTGVRVLTVCLGATDTALL 608 + GVRV V G T +L Sbjct: 198 L--EGAAAGVRVNAVAPGPVATEML 220 >UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Polaribacter dokdonensis MED152|Rep: Short-chain dehydrogenase/reductase SDR - Polaribacter dokdonensis MED152 Length = 259 Score = 76.2 bits (179), Expect = 7e-13 Identities = 61/193 (31%), Positives = 96/193 (49%), Gaps = 8/193 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K ITGA++G+G+ +I G + I+ +++ Q L+ +L K+G D+ Sbjct: 3 KTALITGASSGLGKEFAKIHAKNG-GDLVIVARSKDKLQKLKEKLEKKHGVHVSIIEKDL 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG-IYKKA-------IEVNVTALITST 380 T+ + N V + ID +INNA IG +++A I++N+ AL T Sbjct: 62 TEPNAAQEVYNFVKFSKIEIDYLINNAGF--GGIGKFHERAWAQDLAMIQLNIIALTDLT 119 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 K + + + GK ++NVSS A+L + +YFATK+ V FSN I H +K Sbjct: 120 RKFLPDFVERNQGK---ILNVSSTASLMAGPMQAVYFATKAFVTSFSNAIAEELHDTK-- 174 Query: 561 VRVLTVCLGATDT 599 V V T+ GAT T Sbjct: 175 VTVTTLMPGATKT 187 >UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase family protein; n=1; Gramella forsetii KT0803|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 271 Score = 76.2 bits (179), Expect = 7e-13 Identities = 52/202 (25%), Positives = 103/202 (50%), Gaps = 6/202 (2%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 ++++K V ITG A+GIG + + +++G + ILDI + A Q ++ +L + F Sbjct: 3 KFRNKTVLITGGASGIGLLLTKFSIEKGASALIILDIDKPALQQVELQLKTNICQILSF- 61 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALIT 374 +D+++E + + + +D++INNA ++ ++ + ++VN A + Sbjct: 62 ETDLSNEIQIENAVKKITAQNLQVDILINNAGVVTGKNFSEHNLEDIDRNMQVNAIAPMK 121 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 T + M K K G ++N+SS A++ + M +Y A+K A+ +S+ + + Sbjct: 122 LTKLLLPEMLKR---KSGHIVNISSAASMLSNPGMSVYCASKWAMTGWSDSLRLEMERER 178 Query: 555 TGVRVLTVCLGATDTALLTDEK 620 TG++VLTV DT + K Sbjct: 179 TGIKVLTVTPYYIDTGMFEGVK 200 >UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE - Wolinella succinogenes Length = 247 Score = 75.8 bits (178), Expect = 9e-13 Identities = 45/166 (27%), Positives = 83/166 (50%), Gaps = 6/166 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 ++ K V ITG++ GIG + R+L + G+K L+AE+ +K G + Sbjct: 2 KFSGKNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVI 60 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALIT 374 D TDEE F+ + ++ G + ++NNA + ND + I ++ IE N+T+ Sbjct: 61 SFDATDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFI 120 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 512 + +A++ M K + G+V+N+SS+ + Y A+K ++ Sbjct: 121 GSREALKSMSKQ---RFGSVVNISSIVGERGNAGQTNYSASKGGMI 163 >UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase - Candidatus Kuenenia stuttgartiensis Length = 239 Score = 75.8 bits (178), Expect = 9e-13 Identities = 51/193 (26%), Positives = 100/193 (51%), Gaps = 7/193 (3%) Frame = +3 Query: 51 VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 + +TG + GIG+++ ++ + EG V H +D E+ L+ E +S G+ + ++ Sbjct: 1 MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 392 DVTD +++ +V++ G IDV+INNA ++ D + A + N + +T Sbjct: 56 DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115 Query: 393 EIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 + + +H G + GT+IN++S++ +T Y A K V+ F+ + + + +RV Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSK--ELAPFCIRV 173 Query: 570 LTVCLGATDTALL 608 TV G +T ++ Sbjct: 174 NTVAPGVIETDII 186 >UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 246 Score = 75.8 bits (178), Expect = 9e-13 Identities = 55/195 (28%), Positives = 97/195 (49%), Gaps = 6/195 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K+K ITG+A GIG + + EG K + + D E G + +AE + G T FY+ Sbjct: 4 KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 380 DV + E + V+++ G ID++INNA + D++ +++ ++VN+T + T Sbjct: 62 DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + + + GK G +IN +S + L + Y A+K+AV+ + + F G Sbjct: 122 QALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAK--EFGPKG 176 Query: 561 VRVLTVCLGATDTAL 605 + V V G +T + Sbjct: 177 INVNAVAPGVIETEM 191 >UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP protein - Arabidopsis thaliana (Mouse-ear cress) Length = 629 Score = 75.8 bits (178), Expect = 9e-13 Identities = 57/192 (29%), Positives = 94/192 (48%), Gaps = 17/192 (8%) Frame = +3 Query: 57 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQ---SLQAELNSKYGNKTKF-----Y 212 +TG A+GIG ++ L ++GV + + D +EE GQ SL E N+K+ F Sbjct: 11 VTGGASGIGRALCLALAEKGV-FVTVADFSEEKGQETTSLVREANAKFHQGLSFPSAIFV 69 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN---------DSIGIYKKAIEVNVTA 365 + DVT+ L + + G +D+ INNA + D +K I V++ A Sbjct: 70 KCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDLIA 129 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 ++ T AI+ M K G +IN+ S A L V PIY A+K+ V+ F+ + + Sbjct: 130 VVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---Y 184 Query: 546 FSKTGVRVLTVC 581 + + G+R+ +C Sbjct: 185 YRRQGIRINVLC 196 >UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=225; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae Length = 244 Score = 75.8 bits (178), Expect = 9e-13 Identities = 60/201 (29%), Positives = 98/201 (48%), Gaps = 9/201 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGA+ GIG+++ +L + G K I +E Q++ L G+ K +V Sbjct: 6 KVALVTGASRGIGKAIAELLAERGAKVIGTAT-SESGAQAISDYL----GDNGKGMALNV 60 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 386 T+ E +L A+ E GG+D+++NNA + D++ + K +E N+T++ + Sbjct: 61 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 + M K + G +INV SV + Y A K+ V+ F+ + R + GV Sbjct: 121 VLRGMMKK---RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAR--EVASRGVT 175 Query: 567 VLTVCLG--ATD-TALLTDEK 620 V TV G TD T L DE+ Sbjct: 176 VNTVAPGFIETDMTKALNDEQ 196 >UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 248 Score = 75.4 bits (177), Expect = 1e-12 Identities = 58/193 (30%), Positives = 94/193 (48%), Gaps = 5/193 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITGA +GIG ++ R+ EG K + + D+A E G +L A L + G+ F DV Sbjct: 7 KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 404 TDE ++ A V G +D+++ NA + I++ + V+ +I L + I Sbjct: 64 TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122 Query: 405 KHSGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 K + G GG ++N++S+ A Y A K+AV+ + + ++ G+R Sbjct: 123 KFAAGIMRATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALT--YALQGIRA 180 Query: 570 LTVCLGATDTALL 608 V G DT LL Sbjct: 181 NCVSPGYVDTPLL 193 >UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase, putative; n=26; Gammaproteobacteria|Rep: 3-oxoacyl-(Acyl carrier protein) reductase, putative - Idiomarina loihiensis Length = 254 Score = 75.4 bits (177), Expect = 1e-12 Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 15/217 (6%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 KD V+ ITG A G+G ++ +G K +A++DI + Q + K Y Sbjct: 4 KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 353 D+TDEE + + QE GIDV++NNA L+ D + I ++ ++V Sbjct: 63 DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122 Query: 354 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533 N+T +A M K GK G +IN+SSVA + Y ATK+ V+ + Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVAR-AGNMGQTNYSATKAGVVAMTVTWA 179 Query: 534 RPEHFSKTGVRVLTVCLGATDTALLTDEKLGTFDKYL 644 R + G+R + G +T + K D+ L Sbjct: 180 R--ELGRYGIRCGAIAPGFIETPMTAQMKPEAVDRAL 214 >UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1; Terrabacter sp. DBF63|Rep: Short-chain dehydrogenase/redutase - Terrabacter sp. DBF63 Length = 252 Score = 75.4 bits (177), Expect = 1e-12 Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 7/202 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS+ KV +TG GIG ++L+D G + + + D++E+AG ++ G+ Sbjct: 1 MSNSLDGKVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAV 57 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVT 362 F R+DVTD ++ A V G +D+ NNA L + ++ + K I VN+T Sbjct: 58 AFVRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLT 117 Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542 + S +KA EI + G GG++IN +S Y +K V+ + Sbjct: 118 GVFIS-MKA-EIPQMLAQG-GGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAA--V 172 Query: 543 HFSKTGVRVLTVCLGATDTALL 608 +S G+RV V G T ++ Sbjct: 173 EYSDKGIRVNAVLPGVIQTPMI 194 >UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 261 Score = 75.4 bits (177), Expect = 1e-12 Identities = 63/200 (31%), Positives = 93/200 (46%), Gaps = 11/200 (5%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E KV ITG G G++ L + G H+ + DI + + AEL + G+ T Sbjct: 14 EHAGKVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV- 71 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTA 365 DVTDE ++ +V+ GG+D+++NNA L + + G ++ EVNV Sbjct: 72 TCDVTDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMG 131 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 ++ TL A + M SG G V+N+SS AA Y +K AV F+ R Sbjct: 132 VVICTLAAKDAM---SGRAGAAVVNISSSAAYAN---RTAYGVSKLAVRGFTAQFAR--E 183 Query: 546 FSKTGVRVLTVCLG--ATDT 599 + GVRV + G TDT Sbjct: 184 LAAVGVRVNAIAPGLILTDT 203 >UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactobacillus reuteri|Rep: Short-chain dehydrogenase - Lactobacillus reuteri Length = 277 Score = 75.4 bits (177), Expect = 1e-12 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 8/195 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY----GNKTK 206 +++VV ITG ++GIG+ L E + AI+ + + LQ E+ K G Sbjct: 12 RNEVVLITGGSSGIGKE----LAFEAARRGAIVVVVSRNLEKLQ-EVAKKCLILSGRPAF 66 Query: 207 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 386 Y+ DVTD + +L+ V E GGIDV+IN+A L D I + K++ + T+ L Sbjct: 67 AYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGL-GDFIPVVKESYSSMEKMVHTNLLA 125 Query: 387 AIEI---MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 + I + K +G G +IN+ S+A + +Y ATK+ V+QF N + R E + Sbjct: 126 LMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKAGVIQFDNVL-RME-VAD 183 Query: 555 TGVRVLTVCLGATDT 599 GV+VLTV G DT Sbjct: 184 YGVQVLTVNPGPIDT 198 >UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=16; Pseudomonas|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas aeruginosa PA7 Length = 266 Score = 75.4 bits (177), Expect = 1e-12 Identities = 55/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 + ITGA++GIG ++ L G + + ++ +A +S+ EL ++G + F D+ Sbjct: 3 RYALITGASSGIGLALAEALARRG-RALILVARQRDALESIAYELAQRFGVEVLFRTCDL 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386 + G+L+ + Q + ID+++NNA + ++ ++ IE+N+ AL + Sbjct: 62 AEPLQLSGLLHELEQGERQIDLLVNNAGIGSAGPFVDQEWAREQELIELNILALA----R 117 Query: 387 AIEIMGKHSGGKGG-TVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 +G +GG ++NV+SVAA M Y+A+K+ VL FS G E V Sbjct: 118 LCHALGTRMAAQGGGQILNVASVAAFQPGAWMSNYYASKAYVLHFSE--GLREELKARAV 175 Query: 564 RVLTVCLGATDTALLTD 614 +V +C G T TA + Sbjct: 176 KVSVLCPGPTRTAFFRE 192 >UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 266 Score = 75.4 bits (177), Expect = 1e-12 Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 ++ +TGAA GIGE + R EG + + D +E G ++ +L G + +F R D Sbjct: 8 NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 392 V+ E +G ++ V+ G +D+++NNA + I KK E AL + +T A+ Sbjct: 66 VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125 Query: 393 EIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 E H KG G VIN++S+ + Y K AV +S R ++ G+ V Sbjct: 126 ERALPHMKAKGWGRVINMASLNGVNAHMGSADYNVAKEAVRAYSRTAAR--EWAPYGICV 183 Query: 570 LTVCLGATDTA 602 +C A A Sbjct: 184 NVICPAAVSAA 194 >UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Enterobacter sp. 638|Rep: Short-chain dehydrogenase/reductase SDR precursor - Enterobacter sp. 638 Length = 242 Score = 75.4 bits (177), Expect = 1e-12 Identities = 60/200 (30%), Positives = 100/200 (50%), Gaps = 6/200 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M+ E K +V +TGA++GIGE++ R L G++ + +L E L +EL G+ Sbjct: 1 MNIEKKKRVAVVTGASSGIGEALARELAGNGIQ-VVLLARRFERIDVLASEL----GHGA 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365 ++DVTD E + N V Q GG+D++INNA +M + + +++ +E N+ Sbjct: 56 IAIKADVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLG 115 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 +T T E+ G ++N+SSVA +Y ATK + +S + R E Sbjct: 116 AMTVT----EVFLPQLRRNKGDLVNISSVAGRVAPSGFAVYAATKWGINGWSEAL-RVE- 169 Query: 546 FSKTGVRVLTVCLGATDTAL 605 + +RV+ + GA T L Sbjct: 170 -LQPDIRVMVIEPGAIATEL 188 >UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative 3-oxoacyl-[acyl-carrier protein] reductase - Arthrobacter aurescens (strain TC1) Length = 261 Score = 75.4 bits (177), Expect = 1e-12 Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 6/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K V +TGA +G+G +V + L EG I + D++E++ + + NS + +DV Sbjct: 9 KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386 D + I+N V+E G +DV++NNA + S +++ ++VNV L +T Sbjct: 67 GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A+ H G ++N +SV+ + + Y A+K AV+ F+ + +++ GVR Sbjct: 127 AL----PHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVA--VDYAQRGVR 180 Query: 567 VLTVCLGATDTALL 608 V G T LL Sbjct: 181 CNAVAPGPVLTPLL 194 >UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specificities; n=2; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 261 Score = 75.4 bits (177), Expect = 1e-12 Identities = 56/203 (27%), Positives = 97/203 (47%), Gaps = 9/203 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGA +GIG L + G ++ + + E G+ A+++++ G++ F +DV Sbjct: 13 KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383 + E ++ A ++ G +D+ +NNAAL D+ I ++K I VN+ + L Sbjct: 72 SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 K E+ G GG++IN+SS M Y A K + + + G+ Sbjct: 131 K-WELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVEN--GRHGI 187 Query: 564 RVLTVCLG--ATDTALLTDEKLG 626 RV + G ATD + T ++LG Sbjct: 188 RVNALAPGGVATDLTMATMQELG 210 >UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Mycobacterium|Rep: Probable oxidoreductase ephD - Mycobacterium bovis Length = 592 Score = 75.4 bits (177), Expect = 1e-12 Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 6/195 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 D +V +TGA +GIG EG + I I DI E + AE+ ++ G Y D Sbjct: 324 DTLVSVTGAGSGIGRETALAFAREGAE-IVISDIDEATVKDTAAEIAAR-GGIAYPYVLD 381 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 383 V+D E V E G D+V+NNA + ++ + + + VN+ ++ Sbjct: 382 VSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCR 441 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 + + + G GG ++NVSS+AA + Y +K+A FS+C+ R E GV Sbjct: 442 AFGQRLVER--GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL-RAE-LDAAGV 497 Query: 564 RVLTVCLGATDTALL 608 + T+C G DT ++ Sbjct: 498 GLTTICPGVIDTNIV 512 >UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus thuringiensis Length = 247 Score = 74.9 bits (176), Expect = 2e-12 Identities = 50/196 (25%), Positives = 98/196 (50%), Gaps = 6/196 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TG A GIG+++ L EG K + + ++EA ++L EL K G+ ++DV Sbjct: 7 KVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEAAENLVNEL-GKEGHDVYAVQADV 65 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386 + E ++ V G +D+++NNA + D + +++ I+VN++++ +T Sbjct: 66 SKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSVFNTTSA 125 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 + + + + G +I++SS+ Y A K+ +L F+ + +KT V Sbjct: 126 VLPYI---TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL--ELAKTNVT 180 Query: 567 VLTVCLGATDTALLTD 614 V +C G DT ++ + Sbjct: 181 VNAICPGFIDTEMVAE 196 >UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Proteobacteria|Rep: P-cumic alcohol dehydrogenase - Pseudomonas putida Length = 252 Score = 74.9 bits (176), Expect = 2e-12 Identities = 61/194 (31%), Positives = 94/194 (48%), Gaps = 9/194 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 KDKV +TGAATGIG ++VR L EG K + I D+ + ++ AEL + + Sbjct: 4 KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 371 DV+D + + A + G IDV++NNA + +SI + + K VNV Sbjct: 58 DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 L A + G GG +IN++SV A + M Y ++K AV + + R + Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATT 174 Query: 552 KTGVRVLTVCLGAT 593 K G+ V ++ G T Sbjct: 175 KAGISVNSISPGYT 188 >UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; Bacillus sp. SG-1|Rep: Putative uncharacterized protein - Bacillus sp. SG-1 Length = 260 Score = 74.9 bits (176), Expect = 2e-12 Identities = 61/202 (30%), Positives = 95/202 (47%), Gaps = 7/202 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K+KVV ITGA++G+G + + + +E+ +L EL K+G K Sbjct: 2 KNKVVVITGASSGLGVEFAKQFAGRSYD-LVLTARSEDKLNNLAKELEGKHGIKAHVIPI 60 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGIYKKA--IEVNVTALITST 380 D++ + VV +++INNA + I K+ IEVN+TAL T Sbjct: 61 DLSQHGSAKTLHEKVVSLGLTTEILINNAGFGLFGEFEDTDIQKEVDMIEVNITALTELT 120 Query: 381 LKAIEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + GK G G ++NV+SVAA +M +Y+ATK+ VL S + + Sbjct: 121 ----KYFGKEMVVGNTGKILNVASVAAFQPGPLMAVYYATKAYVLSLSEALS--NEWKDK 174 Query: 558 GVRVLTVCLGATDTALLTDEKL 623 GV+V +C GAT+T +L Sbjct: 175 GVKVSVLCPGATETGFSNSAEL 196 >UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=8; root|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 74.9 bits (176), Expect = 2e-12 Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K + +TG +GIG + V +L+ G ++ + DI +EAG+++ A G K ++R D+ Sbjct: 7 KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVVATS----GGKAAYFRCDI 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 383 EE ++ + GG+D NNAA L S+ +++++++NVT T Sbjct: 62 AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 +I+ G G+++N +S A + + Y K AV+ + + K G+ Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAA--ADYGKHGI 177 Query: 564 RVLTVCLGATDTALL 608 RV + GA T +L Sbjct: 178 RVNALVPGAVRTPML 192 >UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Burkholderiaceae|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 74.5 bits (175), Expect = 2e-12 Identities = 51/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 +KV +TGAA+G+G + +L EG + + + DI E+AG++L E+ G+ F R D Sbjct: 6 NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383 + DE + + + + G +DV++NNAA+ + S+ +++ + N Sbjct: 61 IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 AI M G+++ +SSVAAL +M Y +K AV + + H ++G Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVA--VHCKRSGY 176 Query: 564 RV 569 R+ Sbjct: 177 RI 178 >UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB5) Length = 263 Score = 74.5 bits (175), Expect = 2e-12 Identities = 52/195 (26%), Positives = 88/195 (45%), Gaps = 7/195 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 +VV +TG A+GIG + +G + + DI + G E + G++ ++ R+DV Sbjct: 21 RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383 TDE ++ V G +DV NNA + S I ++ I VN+ + S Sbjct: 79 TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 + + S G G ++N +SV L Y A K V+ + C + ++G+ Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAAL--EYGRSGI 193 Query: 564 RVLTVCLGATDTALL 608 R+ VC G +T L+ Sbjct: 194 RINAVCPGYIETPLV 208 >UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/reductase; n=3; Proteobacteria|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 274 Score = 74.5 bits (175), Expect = 2e-12 Identities = 54/201 (26%), Positives = 100/201 (49%), Gaps = 12/201 (5%) Frame = +3 Query: 21 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNK 200 K + ++KV +TGA G+G + R L G + +A++DI EA ++ A++ G + Sbjct: 5 KAGGKLENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GER 59 Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKA 344 R+DV+ E +++AV++ G ID++ NNAA+++D S+ ++ +A Sbjct: 60 AMSVRTDVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRA 119 Query: 345 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 524 + VN+ + AI M + G GG++I+ SS M Y A+K+ + S Sbjct: 120 MAVNLRGAMLCCKHAIPAMLR---GGGGSIIHSSSGFGAQGDFTMSAYAASKAGLAMLSK 176 Query: 525 CIGRPEHFSKTGVRVLTVCLG 587 + + K +R T+ +G Sbjct: 177 SVA--AQYGKERIRSNTIQIG 195 >UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 246 Score = 74.5 bits (175), Expect = 2e-12 Identities = 57/196 (29%), Positives = 94/196 (47%), Gaps = 5/196 (2%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K KV +TGA GIG++ EG H+A++DI ++ AE+ ++ + ++ Sbjct: 4 KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDINMAGAEATVAEI-TRLDGRALAVQA 61 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398 DV+ ++ V+ G IDV++NNA + D+ + K E A+I LK + + Sbjct: 62 DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119 Query: 399 MGK----HSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 + H +G G++INVSS+ L + Y ATK V+ + R +GV Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR--ELGPSGV 177 Query: 564 RVLTVCLGATDTALLT 611 RV V G T ++T Sbjct: 178 RVNAVTPGFIATEMIT 193 >UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase FadB2x - Pseudomonas stutzeri (strain A1501) Length = 258 Score = 74.5 bits (175), Expect = 2e-12 Identities = 67/219 (30%), Positives = 100/219 (45%), Gaps = 17/219 (7%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 +DKVV ITG A+G+G + L E IAI D+ EAG+ A L ++ + F + Sbjct: 4 QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 365 DV+ EE ++AV+ G I V IN AA+ + + +A +N+ Sbjct: 61 DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120 Query: 366 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536 + K E M K+ +G + G VINVSS AA Y ATK+ V+ + R Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAAR 180 Query: 537 PEHFSKTGVRVLTVCLG---ATDTALLTDEKLGTFDKYL 644 GVRV + G T A L ++ LG+ + + Sbjct: 181 --ELGAIGVRVNAIAPGLFLTTMVAALDEKVLGSLKEQM 217 >UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase; n=1; Pyrococcus abyssi|Rep: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase - Pyrococcus abyssi Length = 240 Score = 74.5 bits (175), Expect = 2e-12 Identities = 57/202 (28%), Positives = 98/202 (48%), Gaps = 7/202 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 E K KV ITGA+ GIG ++ L GV + EE + + EL +YG +T Sbjct: 2 ELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLV 60 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALI 371 ++DV++ E ++ V+ + G ID++INNA ++ D + + + + I VN+ Sbjct: 61 KADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAF 120 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 T + + M K G ++N++S+A V P Y A+K ++ + + R H + Sbjct: 121 IVTQEVLRYM------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR--HLA 172 Query: 552 KTGVRVLTVCLGATDTALLTDE 617 + V V G DT +L+ E Sbjct: 173 -PNILVNAVAPGPVDTDMLSSE 193 >UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) Length = 256 Score = 74.5 bits (175), Expect = 2e-12 Identities = 53/188 (28%), Positives = 96/188 (51%), Gaps = 4/188 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K ITG+A GIG + + EG + +AI DI EA ++ AE+ G DV Sbjct: 6 KTALITGSARGIGRAFAEAYVREGAR-VAIADINLEAARATAAEI----GPAACAIALDV 60 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIEI 398 TD+ + ++ G ID+++NNAAL + + + I +++ + ++ TL ++ Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120 Query: 399 MGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 + + +GG+GG +IN++S A ++ +Y ATK+AV+ + G + + G+ V Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLIRHGINVN 178 Query: 573 TVCLGATD 596 + G D Sbjct: 179 AIAPGVVD 186 >UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 256 Score = 74.1 bits (174), Expect = 3e-12 Identities = 58/200 (29%), Positives = 92/200 (46%), Gaps = 10/200 (5%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 +D+V ITGAA+G G + ++ EG K +A DI E Q E+ G T + Sbjct: 4 EDRVAVITGAASGQGRAAAKLFASEGAKVVA-ADIDEGGAQRTVEEIKEAGGEATA-VKV 61 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV-----TALITSTL 383 DV+ E ++ + G +DV+ NNA + + G K A V A++ L Sbjct: 62 DVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINL 121 Query: 384 KAIEIMGKHS----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548 K + + KH+ +G G++IN +S+ AL Y A K V+ FS + + Sbjct: 122 KGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLA--VEW 179 Query: 549 SKTGVRVLTVCLGATDTALL 608 G+RV +C G DT ++ Sbjct: 180 GPRGIRVNCICPGGVDTPMI 199 >UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivorax borkumensis SK2|Rep: Oxidoreductase, putative - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 581 Score = 74.1 bits (174), Expect = 3e-12 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 7/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K V ITGA +GIG G + DI E + + ++ G + + DV Sbjct: 315 KRVIITGAGSGIGRETALAFARRGAL-VVCTDINSEEAAATARTITAE-GGEALSRKCDV 372 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALIT-STL 383 ++ + V +E G D+V+NNA +L++ S+ +++ + VN+ +I S L Sbjct: 373 SNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKDWQQVLGVNLWGVIHGSRL 432 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 A +++ + G+ G ++N++S AA S ++P Y +KSAVL FS C+ R E + + Sbjct: 433 FARQMIDQ---GRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMFSECL-RAE-MDEHNI 487 Query: 564 RVLTVCLGATDTAL 605 V +C G +T + Sbjct: 488 GVSAICPGIINTPI 501 >UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain dehydrogenase/reductase SDR precursor - Xanthobacter sp. (strain Py2) Length = 261 Score = 74.1 bits (174), Expect = 3e-12 Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 8/201 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 KDK + ITGAA GIG ++ + L +G + I + D++E A +++ E+ + G Sbjct: 5 KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 380 DV +L+ V G +DV+ NNA + ++ + ++ +VN ++ Sbjct: 63 DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 +AI+ K GG GG ++N +S+AA + Y A+K AV+ + R F K Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARA--FGKDQ 178 Query: 561 VRVLTVCLG--ATDTALLTDE 617 + V C G ATD + D+ Sbjct: 179 ITVNAFCPGVVATDMWKIIDK 199 >UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 255 Score = 74.1 bits (174), Expect = 3e-12 Identities = 58/207 (28%), Positives = 101/207 (48%), Gaps = 7/207 (3%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 +KD+VV ITGA+ G+G+ + +G K +A+ D+ A L EL + G + Sbjct: 4 FKDQVVLITGASGGLGKEAAKQFAQQGAK-LALCDLNVAALNDLGTEL-IEQGYEVFSQP 61 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALIT 374 DV++E+ ++ G +DV INNA L + +++ +++NV + Sbjct: 62 CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 I M K GG + N+SSVA ++ + M Y A+K AV+ + + + + Sbjct: 122 CMKYQIPHMIKQG---GGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVA--HEYGR 176 Query: 555 TGVRVLTVCLGATDTALLTDEKLGTFD 635 G+RV +VC T T ++ ++ L T D Sbjct: 177 AGIRVNSVCPYITMTDMV-EQHLKTLD 202 >UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Marinomonas sp. MED121|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Marinomonas sp. MED121 Length = 259 Score = 74.1 bits (174), Expect = 3e-12 Identities = 58/185 (31%), Positives = 90/185 (48%), Gaps = 6/185 (3%) Frame = +3 Query: 51 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230 V +TG A+GIGE++V+ L +G ++ DI EEAG+ L LNS +G K F D+TD Sbjct: 20 VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77 Query: 231 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 392 E + A ++ G I ++NNAA L S + + + VN+ + K Sbjct: 78 IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 +M + GG++IN+SS + + P Y K+ + + + R T VRV Sbjct: 138 PLMAE---AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALAR--ELGPTKVRVN 192 Query: 573 TVCLG 587 TV G Sbjct: 193 TVLPG 197 >UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 265 Score = 74.1 bits (174), Expect = 3e-12 Identities = 55/197 (27%), Positives = 93/197 (47%), Gaps = 6/197 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITGA +GIG + + EG + I + D+ E GQ+ + G + F ++DV Sbjct: 16 KVALITGAGSGIGRATALLFATEGAQ-IVVCDLDPEGGQATVRAIEQA-GAQALFVQADV 73 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386 + ++ +DV+ NNA + ++ S + + VNV ++ + + Sbjct: 74 AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A+ +M + GG ++IN S L Y A K AV+ + + +H + +R Sbjct: 134 AVPVMAEQGGG---SIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMAL-DHGPQR-IR 188 Query: 567 VLTVCLGATDTALLTDE 617 V +VC G TDTA+L DE Sbjct: 189 VNSVCPGDTDTAMLRDE 205 >UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=18; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Arthrobacter sp. (strain FB24) Length = 263 Score = 74.1 bits (174), Expect = 3e-12 Identities = 60/208 (28%), Positives = 98/208 (47%), Gaps = 18/208 (8%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTK-FYR 215 K V ITG A+G+G + R L D G + ++D+ G++ AELN+ G T F Sbjct: 4 KGTVALITGGASGLGAATARRLFDAGAS-VVLVDLPSSRGEAFAAELNAASGAGTAVFVP 62 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS----------IGIYKKAIEVN--- 356 +DVT EE + A V G + +V+N A + + + + I++N Sbjct: 63 ADVTSEEQVQAAVAAAVA-LGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINLVG 121 Query: 357 ---VTALITSTLKAIEIMGKHSGG-KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 524 V L + + A E + GG + G +IN +SVAA P Y A+K AV + Sbjct: 122 TFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMTL 181 Query: 525 CIGRPEHFSKTGVRVLTVCLGATDTALL 608 I R +++ +RV+T+ G +T ++ Sbjct: 182 PIAR--ELARSLIRVVTIAPGIFETPMM 207 >UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 292 Score = 74.1 bits (174), Expect = 3e-12 Identities = 54/209 (25%), Positives = 97/209 (46%), Gaps = 6/209 (2%) Frame = +3 Query: 9 YGTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSK 188 Y + + + KV F+TG A+GIG +V + EG K +AI+D+ + + ELN + Sbjct: 24 YYSTNQNGRMEKKVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQR 82 Query: 189 YGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIE 350 + T DV++EE + V+ GG+DV+++NA L + + ++K + Sbjct: 83 FPGSTISVECDVSNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMA 142 Query: 351 VNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530 V++ T A++ K +GGT++ + SV + S Y K + C Sbjct: 143 VHLDGAFLCTKYAMQEF-KKDIKRGGTILYMGSVHSKYASEYKIPYVTAKHGLEGL--CR 199 Query: 531 GRPEHFSKTGVRVLTVCLGATDTALLTDE 617 G +K +R +C G T L+ ++ Sbjct: 200 GVAREGAKHNIRANLICPGFVLTPLVKNQ 228 >UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC80593 protein - Strongylocentrotus purpuratus Length = 258 Score = 73.7 bits (173), Expect = 4e-12 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 7/186 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 + V ITG+A G+G + + G + + +LDI E + L EL SK G Y D+ Sbjct: 63 RTVLITGSANGLGRLLAQEFARRGAQ-LVLLDIDIEGNKLLAEELCSK-GRSAHAYYCDL 120 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386 + + ++ + ++ G +D++INNAA ++ S +K EVN A I T Sbjct: 121 SRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKA 180 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG-RPEHFSKTGV 563 + M K G V+N++S+A + + Y A+KSA++ F+ +G + TGV Sbjct: 181 LLPDMLNR---KQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGV 237 Query: 564 RVLTVC 581 + VC Sbjct: 238 HLSLVC 243 >UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; Leptospira|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Leptospira interrogans Length = 247 Score = 73.7 bits (173), Expect = 4e-12 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 2/189 (1%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K+K V +TG+ GIG EG K+ I G S Q + G+ K + + Sbjct: 8 KNKTVLVTGSTRGIGRYFA-----EGFKNAGA--IVYGTGSS-QESIKKFDGSGIKGFAA 59 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 392 D+ + I+ ++V+E G +DV++NNA + ++ + K E+ + T +A Sbjct: 60 DIRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRAC 119 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 K KGG +IN++S+ + + + +Y TK AV+ + + + +G RV Sbjct: 120 TAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALA--VEWIGSGYRVN 177 Query: 573 TVCLGATDT 599 +C G DT Sbjct: 178 AICPGFIDT 186 >UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, putative; n=25; Alphaproteobacteria|Rep: 20-beta-hydroxysteroid dehydrogenase, putative - Silicibacter pomeroyi Length = 250 Score = 73.7 bits (173), Expect = 4e-12 Identities = 59/202 (29%), Positives = 94/202 (46%), Gaps = 8/202 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K K V ITGA+ GIG R+ G ++ +L + EA + AE+ G++ Sbjct: 5 KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 374 DV D G +NA V GG+DV+INNA ++ +D +G + AI++N+ + Sbjct: 60 DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554 A+ +M K GGT++ VSS AA Y A+K+ + C+ E Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAAHNPVEAWSHYCASKAGAAMLTACLHLEE--GH 173 Query: 555 TGVRVLTVCLGATDTALLTDEK 620 G+R + + G T + + K Sbjct: 174 HGIRAMGLSPGTVATQMQREIK 195 >UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2; Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 247 Score = 73.7 bits (173), Expect = 4e-12 Identities = 59/201 (29%), Positives = 95/201 (47%), Gaps = 6/201 (2%) Frame = +3 Query: 51 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230 + ITGA +GIG R EG +A++D E A Q E + DVTD Sbjct: 10 IVITGAGSGIGRESARQFAREGAT-LALIDRDEAAAQVTADETGGHV------FALDVTD 62 Query: 231 EEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLKAI 392 E ++ + GGID ++N+A ++ D IG+ +++ ++VN+T A+ Sbjct: 63 EAAVETVVGRAAEALGGIDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQAAL 122 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 + K ++N++S AL S Y A+K+AV+ FS I + VRV Sbjct: 123 PWLRKE---PKAAIVNIASAQALLPSLTGSAYAASKAAVMMFSKSIAKE---LAPAVRVN 176 Query: 573 TVCLGATDTALLTDEKLGTFD 635 +C GAT+T +TD+ + D Sbjct: 177 IICPGATETP-MTDQGVAPDD 196 >UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 73.7 bits (173), Expect = 4e-12 Identities = 59/203 (29%), Positives = 96/203 (47%), Gaps = 6/203 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K +TGA +GIG ++ EG + +A+ D+ E A + + AE+ G R+DV Sbjct: 7 KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386 T E G++ + GG++V++NNA + S +++ + VN+ Sbjct: 62 TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 AI + + SG GG VIN+SS+AAL Y A K +L + G +H + GVR Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAALVGLKDRAAYSAAKGGILALTRA-GAIDHIHE-GVR 176 Query: 567 VLTVCLGATDTALLTDEKLGTFD 635 V + G +T ++ G D Sbjct: 177 VNCIAPGTVETPWISRITAGYAD 199 >UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Putative uncharacterized protein - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 247 Score = 73.7 bits (173), Expect = 4e-12 Identities = 63/201 (31%), Positives = 99/201 (49%), Gaps = 9/201 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV+ ITGA++GIGE++ + G K I + EE + ++A++ + G + ++ +DV Sbjct: 5 KVIVITGASSGIGEAIAKKQAAAGDK-IVLGARREENLKQIKADIEAG-GGQAEYLVTDV 62 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386 TD E + + G IDV INNA LM S+ I + + I+VN+ + Sbjct: 63 TDVEQVKALAQKAMDAYGRIDVWINNAGLMPHSLLIDARIDDWNRMIDVNLKGTLYGIAA 122 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A I + G IN+ SVA+L +Y ATK AV S + E + VR Sbjct: 123 AQHIFHDQNTGH---FINLGSVASLYSHAGGAVYSATKWAVKAISESLREEEAQAGKNVR 179 Query: 567 VLTVCLGATDTAL---LTDEK 620 V ++ GA ++ L +TD K Sbjct: 180 VTSLYPGAIESELVANMTDSK 200 >UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 287 Score = 73.7 bits (173), Expect = 4e-12 Identities = 56/195 (28%), Positives = 95/195 (48%), Gaps = 8/195 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITG +GIG V + L EG K +A D+ + G++++ EL G + R++V Sbjct: 7 KVAIITGGTSGIGRGTVDLFLKEGAKVVAA-DLQDHKGEAMEREL----GENFSYCRANV 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN-----VTALITSTLKA 389 E+ +++ V++ G +D++ NNA +G + I++N V L+ + Sbjct: 62 AHEDEVKNLVDHTVKKFGKLDILFNNAGY--GGVGGELQEIDMNGFDETVGVLLKGVVLG 119 Query: 390 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC--IGRPEHFSKTG 560 + H K G++I+ +SVA L + +Y A K+AV FS C + HF Sbjct: 120 YKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAALELAPHF---- 175 Query: 561 VRVLTVCLGATDTAL 605 VR +C G T++ Sbjct: 176 VRSNAICPGGIATSI 190 >UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Sphingomonadaceae|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 261 Score = 73.7 bits (173), Expect = 4e-12 Identities = 53/201 (26%), Positives = 100/201 (49%), Gaps = 8/201 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS + KV +TG + GIG + R+L G + I E+ ++ +AE+ +K G K Sbjct: 1 MSQDMTGKVAIVTGGSDGIGLATARLLAARGAT-VVICARREDKLEAARAEI-AKVG-KV 57 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA 365 + + DV+DE F ++ V G +D+++NNA ++ + + ++K VN A Sbjct: 58 EAVKLDVSDEAAFTALVEDVAARHGRLDMLVNNAMSVHYAPIAKLRLDHWRKDFAVNADA 117 Query: 366 LITSTLKAIEIMG--KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539 + T A+++M + G + G ++N++S + + M Y A+K+A++ F+ Sbjct: 118 VFVGTKAAMKVMAAQEQRGRQRGAIVNIASTCGIRAAPNMASYSASKAAMVHFTAAAAM- 176 Query: 540 EHFSKTGVRVLTVCLGATDTA 602 + G+RV + G TA Sbjct: 177 -EGAPLGIRVNAIVPGQVMTA 196 >UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium gilvum PYR-GCK Length = 543 Score = 73.7 bits (173), Expect = 4e-12 Identities = 59/193 (30%), Positives = 87/193 (45%), Gaps = 4/193 (2%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 D +V +TGAA+GIG + G + I D+ AG A L + G Y D Sbjct: 274 DTLVAVTGAASGIGRATALAFAHHGAD-VVISDV-NAAGLDETARLVTSAGVHAYPYTVD 331 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT--STLKAIE 395 V D V E G DVV+NNA + + + A E + I + Sbjct: 332 VADAAAVEAFAEQVCAEHGVPDVVVNNAGVGHAGFFLDTPAEEFDRVLDINFGGVVNGCR 391 Query: 396 IMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569 GK G GG ++NV+S+A+ T +VM Y +K+AV FS+C+ R E G+ + Sbjct: 392 SFGKRLADRGVGGHIVNVASMASYTPVNVMNAYCTSKAAVFMFSDCL-RAE-LDSFGIGL 449 Query: 570 LTVCLGATDTALL 608 T+C G T ++ Sbjct: 450 TTICPGFISTNIV 462 >UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Reinekea sp. MED297|Rep: Short-chain alcohol dehydrogenase-like protein - Reinekea sp. MED297 Length = 672 Score = 73.7 bits (173), Expect = 4e-12 Identities = 51/170 (30%), Positives = 90/170 (52%), Gaps = 9/170 (5%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELN-SKYGNKTKFYRSD 221 KVV ITG ++GIG++ L G ++ A +A + +A L+ G +++D Sbjct: 385 KVVLITGGSSGIGKATAMRLSKAGA---TVIICARDAEKLRRAHLDIESTGGTVVSHQAD 441 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVNVTALITS 377 +T + + + +E G+D++INNA ++M D + +++ IE+N A + Sbjct: 442 ITQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVAI 501 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 527 TLKA+ +M + + G VIN+SS+ L+ S Y A+K+A+ FS C Sbjct: 502 TLKALPMMDRR---REGHVINISSIGVLSNSPRFSAYVASKAALEAFSRC 548 >UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus coagulans 36D1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 262 Score = 73.7 bits (173), Expect = 4e-12 Identities = 52/199 (26%), Positives = 93/199 (46%), Gaps = 7/199 (3%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 ++ KV +TG GIG + L G ++ + D+++E G+ ++ G + F Sbjct: 5 DFTGKVAIVTGGGGGIGREAC-LKLAAGGANVVVADLSDELGEETAGKIREN-GGEAIFV 62 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALI 371 R+DV+ + + + G ID+++NNA L++ ++ K + +NV + Sbjct: 63 RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 + M K GT++N +SVA L + M Y A+K AV+ + G + Sbjct: 123 LGMKYVLPHMISQ---KSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAA 177 Query: 552 KTGVRVLTVCLGATDTALL 608 +GVRV VC G DT ++ Sbjct: 178 PSGVRVNAVCPGVVDTEMM 196 >UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas naphthalenivorans (strain CJ2) Length = 286 Score = 73.7 bits (173), Expect = 4e-12 Identities = 59/207 (28%), Positives = 103/207 (49%), Gaps = 11/207 (5%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 227 V +TGAA GIG + + L +G++ +A+LD+ +A Q+ AEL S + DVT Sbjct: 21 VAIVTGAADGIGWATAQRLAADGLR-VALLDLRADAAQARAAELGSIHLG----LGCDVT 75 Query: 228 DEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNV--TALITST 380 EE + AV++ G ID ++NNA + S+ + + + V++ T L++ Sbjct: 76 SEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLRGTFLMSRA 135 Query: 381 LKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + + G+G G ++N+ S+A+ T Y A K+ VL + + +++ Sbjct: 136 VARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA--SEWARA 193 Query: 558 GVRVLTVCLGATDTALLTD-EKLGTFD 635 G+RV V G TAL+ + E+ G D Sbjct: 194 GIRVNAVAPGYVRTALVAELERKGAID 220 >UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella pealeana ATCC 700345 Length = 254 Score = 73.7 bits (173), Expect = 4e-12 Identities = 55/191 (28%), Positives = 99/191 (51%), Gaps = 6/191 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS KV ITGAA G+G + R++ EG + + + DI E G+ E+ + GN + Sbjct: 1 MSGRLIGKVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNS 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365 F DVT E + ++N + + G +++++NNAA++ +++ +++ VN + Sbjct: 56 LFIEHDVTKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDS 115 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 + A+ +M K SG GG++IN+SS +A+ Y A+K+A+ S + Sbjct: 116 VFLRIHYALPLMEK-SG--GGSIINMSSSSAVFGMPHFAAYGASKAAIRGLSQSVAVYCS 172 Query: 546 FSKTGVRVLTV 578 +K VR T+ Sbjct: 173 QTKNNVRCNTL 183 >UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster|Rep: CG8757-PA - Drosophila melanogaster (Fruit fly) Length = 266 Score = 73.7 bits (173), Expect = 4e-12 Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 13/216 (6%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 W +KV ++GA+ GIG + R L+ G+ + + E + L++ L+ + ++ + Sbjct: 18 WCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERV-EKLRSGLSLEQQSRLHAIK 76 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM-------NDSIGIYKKAIEVNVTALIT 374 D+T E+ L + ++ GG+DV+++NA ++ D + IE N+ + Sbjct: 77 CDITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVY 136 Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP------IYFATKSAVLQFSNCIGR 536 ++ M K G +G VI V+SVA ++ P IY ATK A+ + + Sbjct: 137 CVRESFRSM-KRRGTEGHVVI-VNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQ 194 Query: 537 PEHFSKTGVRVLTVCLGATDTALLTDEKLGTFDKYL 644 KT VRV TV G DT +L ++ G +++ Sbjct: 195 EFQRHKTAVRVSTVSPGIVDTVILPEQIQGIIKQHM 230 >UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor; n=80; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 319 Score = 73.7 bits (173), Expect = 4e-12 Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 7/187 (3%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQ-AELNSKYGNKTKFYRSDV 224 VV ITGA+ GIG+++ L G K +++ A A ++ + A+ +YG + + DV Sbjct: 78 VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386 + ++ + + G IDVV+NNA + D++ I + + I +N+T + T Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A++IM K K G +IN+SSV L + Y A K V+ FS R E S+ + Sbjct: 196 AVKIMMKK---KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAR-EGASR-NIN 250 Query: 567 VLTVCLG 587 V VC G Sbjct: 251 VNVVCPG 257 >UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=6; Clostridium|Rep: Predicted short-chain dehydrogenase - Clostridium acetobutylicum Length = 262 Score = 73.3 bits (172), Expect = 5e-12 Identities = 50/188 (26%), Positives = 91/188 (48%), Gaps = 5/188 (2%) Frame = +3 Query: 51 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230 V ITGA+TGIG + RI G + ++ +E EL K + D++ Sbjct: 3 VLITGASTGIGYEITRIFARNG--YDVVITARDE---KRLIELAKNINTKVTVIKKDLSR 57 Query: 231 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 410 + + N + + +D+++NNA M D+ G++ K+ + ++ +K++ I+ + Sbjct: 58 PDSANELFNEIKENNIEVDILVNNAG-MGDT-GLFHKSSVDKINEMLELNIKSLTILTRL 115 Query: 411 SGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 + G ++NV+S + + +Y+ATK+ VL F+ IG E K V+V Sbjct: 116 VSAEMVKKRSGMILNVASTGSYMPGPFIAVYYATKAYVLSFTEAIG--EELKKFNVKVSA 173 Query: 576 VCLGATDT 599 +C GAT T Sbjct: 174 LCPGATAT 181 >UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 254 Score = 73.3 bits (172), Expect = 5e-12 Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KVV ITG A GIG++ ++LLD G K +A++DI E++ + L+ + ++ +V Sbjct: 4 KVVLITGGAGGIGQATAKLLLDYGAK-VALVDINEDSLVKAKESLHVE-DDRVFTITGNV 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383 T EE + V G IDV NNA + I ++K + +NVT + Sbjct: 62 TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLK 121 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 ++ M K G+++N +S AA S M Y A+K AV + + G+ Sbjct: 122 HVMKQMKKQG---YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAAL--EVASDGI 176 Query: 564 RVLTVCLGATDTALLTD 614 RV V A DT +L D Sbjct: 177 RVNAVAPAAIDTQMLAD 193 >UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=1; Oceanobacter sp. RED65|Rep: Putative fatty acyl chain reductase - Oceanobacter sp. RED65 Length = 252 Score = 73.3 bits (172), Expect = 5e-12 Identities = 48/194 (24%), Positives = 98/194 (50%), Gaps = 6/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K+V ITG + +G + V + + + ++++ L A G + R ++ Sbjct: 10 KIVLITGGSGDLGRASVLEFGKQKCRVYFTYNSSKDSADELVASAEES-GFEAFPIRCNI 68 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386 +D+E ++N +V+++G IDV++NNA + D++ +++ I+ N+ T Sbjct: 69 SDKEQVNALVNDIVEKEGKIDVLVNNAGIYKDNLFTSMTDEEFEQVIQTNLYGTFYCTKS 128 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 +++M ++ + G ++NVSS+A +T S Y A K AV+ FS + + +R Sbjct: 129 VVDVMYRN---RCGAIVNVSSIAGVTNSFGQANYSAAKGAVVSFSRTLA--AELAPKNIR 183 Query: 567 VLTVCLGATDTALL 608 V TV G D++++ Sbjct: 184 VNTVAPGLIDSSMV 197 >UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Acidobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 257 Score = 73.3 bits (172), Expect = 5e-12 Identities = 53/193 (27%), Positives = 93/193 (48%), Gaps = 3/193 (1%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV + G TGIG ++ L D G ++ E+ + A+ + G +T SDV Sbjct: 10 KVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAA--ADEIERRGRQTLRVCSDV 67 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAIEI 398 T + NAV+ + +D+++N A + + E N + +T L+A ++ Sbjct: 68 TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPTLTVSEDEWNKILDTNLTGALRACQV 127 Query: 399 MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 GKH +G G +IN++S+++ H + Y A+K+A+L + + +SK GV V Sbjct: 128 FGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLA--VEWSKKGVTVNA 185 Query: 576 VCLGATDTALLTD 614 + G TAL T+ Sbjct: 186 IAPGVFRTALNTE 198 >UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 355 Score = 73.3 bits (172), Expect = 5e-12 Identities = 58/194 (29%), Positives = 93/194 (47%), Gaps = 6/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITG A G GE+ R+ G H+ I D+ EE G+ L AEL G + F DV Sbjct: 102 KVALITGGARGQGEAEARLFAQHGA-HVYICDVLEEEGEKLAAELRGS-GLQADFRFLDV 159 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIG-IYKKAIEVNVTALITSTLK 386 TD E + + + G +DV+INNA + + D+ + + + VN + ++ Sbjct: 160 TDAEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLG-MQ 218 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A + K SG G++IN+ S A + H + Y A+K AV + + +G+R Sbjct: 219 ACAPLMKRSG--NGSIINIGSTAGI-MGHPVAAYSASKWAVRGLTKAAAM--ELASSGIR 273 Query: 567 VLTVCLGATDTALL 608 V + G +T ++ Sbjct: 274 VNAMHPGVVETPMV 287 >UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Stappia aggregata IAM 12614|Rep: Short-chain dehydrogenase/reductase SDR - Stappia aggregata IAM 12614 Length = 270 Score = 73.3 bits (172), Expect = 5e-12 Identities = 54/200 (27%), Positives = 95/200 (47%), Gaps = 8/200 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 +V +TGA+ GIGE+ R L G K + + +++ + + E+ ++ G DV Sbjct: 24 QVALVTGASRGIGEAAARSLAKYGAK-VVLAARSDKDIERIAGEIRAE-GQDATAVVCDV 81 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383 D + + + V GG+D+++NNA ++ I + K I++NV + Sbjct: 82 ADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVIDINVKGVYYG-- 139 Query: 384 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + KH KG GTV+N+SS AA++ Y A+K+A L + C + F G Sbjct: 140 --LHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK--EFGDKG 195 Query: 561 VRVLTVCLGATDTALLTDEK 620 +R++ + G T + D K Sbjct: 196 LRIVGLSPGTVATQMQVDIK 215 >UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Halobacteriaceae|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 254 Score = 73.3 bits (172), Expect = 5e-12 Identities = 55/211 (26%), Positives = 98/211 (46%), Gaps = 9/211 (4%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGQSLQAELNSKYGNKTKF 209 +DKV +TG A+G G ++ R + G + + D + E G+ + ++ F Sbjct: 6 EDKVAVVTGGASGFGRAICRRYAEHGA-DVIVADRQQDPREGGKPTHELVEAETDRTAHF 64 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 371 DVTD + L + A +E GGID+++NNA + + Y + ++VN + Sbjct: 65 VECDVTDPDD-LEVAVAAAEELGGIDIMVNNAGISEIADFYETTEEDYDRLMDVNTKGVF 123 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 A E M ++ GGTVIN+SS + + ++ Y +K AV F+ + + S Sbjct: 124 FGAQVATEAMRENG---GGTVINMSSSGGIRGTGLLVNYCTSKGAVRLFTYALA--DRLS 178 Query: 552 KTGVRVLTVCLGATDTALLTDEKLGTFDKYL 644 +RV + G + T + DE++ K + Sbjct: 179 NYNIRVNAIHPGYSKTQMFEDERIDDTTKMM 209 >UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627; n=13; Bacteria|Rep: Uncharacterized oxidoreductase SSP1627 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 246 Score = 73.3 bits (172), Expect = 5e-12 Identities = 58/196 (29%), Positives = 91/196 (46%), Gaps = 7/196 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215 KDKVV ITGA++GIGE V +L + G K L + L+ ++ K G + + Sbjct: 5 KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 377 +DVT + ++ + G IDV+INNA LM S + + I+VN+ ++ Sbjct: 60 TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + M K K G +IN++SVA +Y TK AV + + + E + Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGS 176 Query: 558 GVRVLTVCLGATDTAL 605 +R + GA T L Sbjct: 177 NIRTTILSPGAVSTEL 192 >UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; n=31; Bacteria|Rep: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase - Bacillus subtilis Length = 261 Score = 73.3 bits (172), Expect = 5e-12 Identities = 51/188 (27%), Positives = 91/188 (48%), Gaps = 3/188 (1%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K+ FITGAA GIGE+V R L +G HIA +D E + + + L ++ + + +DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADV 66 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYKKAIEVNVTALITSTLKAIEI 398 D I + +E G ID+++N A ++ + + + E + T A Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 399 MGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 + K+ + G+++ V S A M Y ++K+A + F+ C+G ++ +R Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL--ELAEYNIRCNI 184 Query: 576 VCLGATDT 599 V G+T+T Sbjct: 185 VSPGSTET 192 >UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP00000025535; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000025535 - Nasonia vitripennis Length = 254 Score = 72.9 bits (171), Expect = 6e-12 Identities = 57/201 (28%), Positives = 100/201 (49%), Gaps = 8/201 (3%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 W KV +TGA+ GIG ++V LLD G + ++ +A + ++ ++ + K Sbjct: 4 WAGKVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRV-EKVKELIDDRPEAKLHAVE 59 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 377 DVT+EE+ + + + G +DV++NNA L + S+ ++ ++VNV L Sbjct: 60 CDVTNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVC 119 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV--MPIYFATKSAVLQFSNCIGRPEHFS 551 T +A+ M + G +I++SS+A V +Y ATK AV + + R E + Sbjct: 120 TREAVRSMRECDG--ESVIIHISSLAGERVPAVPGFNVYPATKRAVNALAQTL-RHE-LA 175 Query: 552 KTGVRVLTVCLGATDTALLTD 614 T +RV T+ G T L+ + Sbjct: 176 GTKIRVTTISPGLVATELMAN 196 >UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep: Bll5898 protein - Bradyrhizobium japonicum Length = 256 Score = 72.9 bits (171), Expect = 6e-12 Identities = 62/201 (30%), Positives = 93/201 (46%), Gaps = 7/201 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M +KDKVV +TGA +GIG + R EG I +L+ E S AE+ ++ G Sbjct: 1 MLSRFKDKVVIVTGAGSGIGAAAARRFHGEGA--IVVLNGRRE---SKLAEVGAELGTDR 55 Query: 204 KFYR-SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVT 362 R +DVT ++ V+ G ID+++NNA + I ++ VNV Sbjct: 56 CMIRPADVTIAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVD 115 Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542 ++ T A+ H GG+++NVSS++ L + Y ATK AV + + Sbjct: 116 GVLYMTRAAL----PHLIESGGSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLAL-- 169 Query: 543 HFSKTGVRVLTVCLGATDTAL 605 F GVR+ VC T T L Sbjct: 170 EFGPRGVRINAVCPSLTLTHL 190 >UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=3; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 258 Score = 72.9 bits (171), Expect = 6e-12 Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 6/184 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K + +TG A GIG ++V+ EG + D+ EE G+ + E + +F R D+ Sbjct: 6 KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 386 TD + + + +E GGIDV++N A L ++ +++ VNV I + Sbjct: 65 TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A IM S G G +IN S++ T Y ++K AV ++ + R + +G+R Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFTGELANATYGSSKGAVHTWTRTVAR--EWGPSGIR 179 Query: 567 VLTV 578 V V Sbjct: 180 VNAV 183 >UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 261 Score = 72.9 bits (171), Expect = 6e-12 Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 13/205 (6%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 227 + ITGA++GIG + R+ +G I + + Q L AEL + + K + +D+ Sbjct: 5 MALITGASSGIGAELARLCAADGYGLILVARRTDRLEQ-LGAELAAAHNVKFRTIAADLA 63 Query: 228 DEEHFLGILNAVVQEQGG--IDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383 + + A+ ++ G ID++INNA + I+VN+TAL T Sbjct: 64 EPD----AATAIYRQTSGDTIDILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTK 119 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 ++ M + G+ ++NV S AA +M +Y+A+K+ V+ FS + + F TGV Sbjct: 120 SYVKDMVRRGSGR---ILNVGSTAAFVPGPLMAMYYASKAFVVSFSEALAK--EFEGTGV 174 Query: 564 RVLTVCLGATDT-----ALLTDEKL 623 V +C G T T A +TD KL Sbjct: 175 TVTVLCPGPTRTEFDAAAGITDSKL 199 >UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=1; Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Algoriphagus sp. PR1 Length = 265 Score = 72.9 bits (171), Expect = 6e-12 Identities = 49/181 (27%), Positives = 95/181 (52%), Gaps = 6/181 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV+ +TG+ TGIG+++ + ++ EG K + I + E+ GQ + +EL + + K + D+ Sbjct: 6 KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 386 ++E +++ V+ G +D ++NNAA++ S + +EVN + T Sbjct: 62 SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 AI + ++ G V+N+ S+ A + H + Y +K A++ + +G F + GVR Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLG-DSLFRENGVR 176 Query: 567 V 569 V Sbjct: 177 V 177 >UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 259 Score = 72.9 bits (171), Expect = 6e-12 Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 8/205 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M+ + +V ITG +GIG + V+ + EG K + I DI + G L +L + Sbjct: 1 MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAK-VVIGDIDDARGHQLVEQLGG--ADVA 57 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNV 359 + DVT +E + G +D+ NNA ++++ + ++K EVN+ Sbjct: 58 TYVHVDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNL 117 Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539 T++ A+ M + G+G + S VA + + Y A+K VL + +G Sbjct: 118 TSVYLCCKAALPHMLEQ--GRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELG-- 173 Query: 540 EHFSKTGVRVLTVCLGATDTALLTD 614 F++ GVRV +C G +T LL + Sbjct: 174 VQFARQGVRVNALCPGPVNTPLLQE 198 >UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Paracoccus denitrificans (strain Pd 1222) Length = 253 Score = 72.9 bits (171), Expect = 6e-12 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 7/195 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M KDKVV ITGA GIG + ++ ++EG + + + D +A + + AEL G Sbjct: 1 MDMHLKDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENA 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365 + + DV+ E +++ V E GG+DV++NNA + ++ I+VN+T Sbjct: 56 RAFTVDVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTG 115 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQS-HVMPIYFATKSAVLQFSNCIGRPE 542 + + A+ + K GG ++N +S A+ + Y A K V + + Sbjct: 116 VYLCSKYAVPELRKRG---GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMAL-- 170 Query: 543 HFSKTGVRVLTVCLG 587 F+ +RV +V G Sbjct: 171 DFAADNIRVNSVAPG 185 >UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2080 Length = 291 Score = 72.9 bits (171), Expect = 6e-12 Identities = 49/181 (27%), Positives = 86/181 (47%), Gaps = 2/181 (1%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K + ITGAA+G+G ++ + EG + I DI +E G + A+LN +Y N F ++ Sbjct: 2 KRILITGAASGLGLALAKKYASEGWS-VCIADIQDEEGIKIAAQLNEEYANDCFFQHLNI 60 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-KAIEVNVTALITSTLKAIEI 398 T + + ++ + + G+D ++NNA + + I + K + V + +K + Sbjct: 61 TSDTQWQELVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHV 120 Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578 G +INV+S+A L M Y +K+ ++ FS G GV+V V Sbjct: 121 CVPLLKESKGLLINVASMAGLLHMGSMSAYNVSKAGMVAFSE--GLLSELDPYGVKVSVV 178 Query: 579 C 581 C Sbjct: 179 C 179 >UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobacterium ulcerans Agy99|Rep: Short-chain dehydrogenase - Mycobacterium ulcerans (strain Agy99) Length = 282 Score = 72.9 bits (171), Expect = 6e-12 Identities = 56/191 (29%), Positives = 91/191 (47%), Gaps = 4/191 (2%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 +VV ITGA +GIG + + G +A+ DI + A A+ +G+ R DV Sbjct: 16 RVVAITGAGSGIGRELALLCAQRGAD-LALCDINDTAVADT-AQTARGFGHDVITRRVDV 73 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAIE- 395 +D E +A + GG+D+++NNA L+ + +K + V+ + + E Sbjct: 74 SDPEQMTAFADATLGHFGGVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVHGCEA 133 Query: 396 -IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 + G+GG V+N+SS A L + + Y ATK AVL S + R E + V Sbjct: 134 FLPAMIESGRGGHVVNLSSAAGLLANPALSAYSATKFAVLGLSEAL-RIE-LEPHRIGVT 191 Query: 573 TVCLGATDTAL 605 +C G +TA+ Sbjct: 192 AICPGVINTAI 202 >UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 72.9 bits (171), Expect = 6e-12 Identities = 66/220 (30%), Positives = 99/220 (45%), Gaps = 19/220 (8%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS--KYGNKTKFYR 215 DKV ITG++ GIG++ R+L EG K AE ++ L + GN Sbjct: 6 DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 365 D+T E ++ + + + G ID+++NNA +N SI Y K E+NV + Sbjct: 65 GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPE 542 +I T KA H G ++N+SS+ A + V P Y K+A+ Q++ Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAA--I 178 Query: 543 HFSKTGVRVLTVCLGATDTAL------LTDEKLGTFDKYL 644 G+RV +V GA T LT+EK F YL Sbjct: 179 DLVPEGIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYL 218 >UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 - Eubacterium sp. (strain VPI 12708) Length = 249 Score = 72.9 bits (171), Expect = 6e-12 Identities = 50/194 (25%), Positives = 92/194 (47%), Gaps = 7/194 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF-YR 215 +DK+ ITG GIG + ++ ++ G K ++I +E + A+L Y + + Sbjct: 5 QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 377 D+T + + + V Q+ G +DV+INNA + +S+ +K +++NV + Sbjct: 64 PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 A + M K G +IN +SV + S Y +K+ V+ ++ +GR + Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGR--EIIRK 178 Query: 558 GVRVLTVCLGATDT 599 +RV+ V G DT Sbjct: 179 NIRVVGVAPGVVDT 192 >UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=25; Proteobacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Burkholderia mallei (Pseudomonas mallei) Length = 265 Score = 72.5 bits (170), Expect = 8e-12 Identities = 49/170 (28%), Positives = 89/170 (52%), Gaps = 8/170 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG-QSLQAELNSKYGNKTKFYR-S 218 K FITGAA G+G ++ R + ++G + + + DI + A ++ AELN G + + Sbjct: 14 KRAFITGAAGGLGRAIARRMAEQGAQ-VFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQ 72 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-DSIG-----IYKKAIEVNVTALITST 380 DV DE + L+ GG+ V+++NA + + +IG +++ + +NV +++ T Sbjct: 73 DVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGT 132 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530 A+ + G +++N+SSVAA Q Y A+K+AV + I Sbjct: 133 KHALPYL---EAGAPASIVNISSVAAFKQEPDYTAYNASKAAVASLTKSI 179 >UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Hahella chejuensis KCTC 2396|Rep: Short-chain alcohol dehydrogenase-like protein - Hahella chejuensis (strain KCTC 2396) Length = 288 Score = 72.5 bits (170), Expect = 8e-12 Identities = 54/198 (27%), Positives = 95/198 (47%), Gaps = 6/198 (3%) Frame = +3 Query: 30 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 209 H + +K V ITGAA+G+G + R L G + +A D+ +E G ++ A L N+ + Sbjct: 2 HRFPEKRVAITGAASGLGLATARHFLSRGWR-VAFADVQDETGSAIVASLGLP-ENRAFY 59 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG-----IYKKAIEVNVTALI 371 DVT +V+ GG+D++INNA + + IG ++ I++++ ++ Sbjct: 60 QHVDVTKVRDIQAWRRKIVETWGGLDILINNAGVAAHGGIGEAPLEDWEWVIDIDLMGVV 119 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 + + + + G ++N++S+A L + M Y A K+ V+ S + S Sbjct: 120 RGCKEFAPLFKRQ---RSGQIVNIASMAGLVHAPEMGSYNAAKAGVVALSETL--VGELS 174 Query: 552 KTGVRVLTVCLGATDTAL 605 GV V VC G T L Sbjct: 175 PFGVGVNVVCPGFFSTGL 192 >UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Bacillus thuringiensis serovar israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 252 Score = 72.5 bits (170), Expect = 8e-12 Identities = 47/201 (23%), Positives = 97/201 (48%), Gaps = 6/201 (2%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 ++K + +TG GIG ++V L EG A ++++ +++EL S Y ++ Y Sbjct: 11 ENKRIIVTGGCKGIGRAIVEKYLQEGAVVAATYYKSKDSSDQMKSELES-YSDRLAIYNM 69 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 380 DV+D E ++ + + GID+++NN+ + DS+ + K I+ N+ + Sbjct: 70 DVSDAEQVNKVMEQIQDDLKGIDILVNNSGITQDSLLYSMKNSDWDKVIKTNLYGPFYTC 129 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + M K K G++IN++SV+ + Y A+K ++ + + + + Sbjct: 130 KSVLLNMIKQ---KYGSIINIASVSGIVGIPGQSNYCASKFGLIGLTKSLAK--ELASKN 184 Query: 561 VRVLTVCLGATDTALLTDEKL 623 +RV + G DT ++ + K+ Sbjct: 185 IRVNAIAPGYVDTEMIDNVKI 205 >UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Polaromonas sp. JS666|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 265 Score = 72.5 bits (170), Expect = 8e-12 Identities = 59/209 (28%), Positives = 102/209 (48%), Gaps = 7/209 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M + K+K V +TG + IG ++V EG HI I D+ E+ Q AEL G + Sbjct: 1 MDIDLKNKSVIVTGGGSNIGRAIVLGFAAEGA-HITIGDVDEQQAQKT-AELALLSGAAS 58 Query: 204 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA---LM---NDSIGIYKKAIEVNVT 362 + ++DVT + + A V + GG+DV++NN LM + +++K I +N Sbjct: 59 AQVVKTDVTQLDQVQAMFKAAVDKFGGVDVLVNNVGWDQLMFFTQTTPDLWQKIIAINYV 118 Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542 ++ T A+++M + G+++++SS A+ +Y K+A+ F I + Sbjct: 119 GVLNCTKTALDLMIPRN---AGSIVSISSDASRQGEPREAVYGGVKAAINSFMKTIAKEN 175 Query: 543 HFSKTGVRVLTVCLGATDTALLTDEKLGT 629 + G+R VC G T + TDE G+ Sbjct: 176 --GRYGIRCNVVCPGITIPS-TTDEVGGS 201 >UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 249 Score = 72.5 bits (170), Expect = 8e-12 Identities = 53/197 (26%), Positives = 97/197 (49%), Gaps = 6/197 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS + +V +TGA++G GE+V L G K +A+ E+ ++L A+ + G + Sbjct: 1 MSMDLSGRVALVTGASSGFGEAVALDLAKAGAK-VALAARREDRLRAL-AQRITDAGGQA 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365 + +D TDE + G +D++INNA +M +G ++ +E+N+ Sbjct: 59 QVIVADFTDEHQAQRAVRETEAAFGWLDILINNAGVMYLEPVATADLGRWRSMLELNLLG 118 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 LI +T A+ M + K G ++N++S A + + Y A+K V+ FS + + H Sbjct: 119 LIAATQAALPGM---TARKDGHIVNIASTAGHIANPLSAAYSASKFGVIGFSESLRKEVH 175 Query: 546 FSKTGVRVLTVCLGATD 596 V V++ + AT+ Sbjct: 176 KDNIRVTVISPGMAATE 192 >UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 254 Score = 72.5 bits (170), Expect = 8e-12 Identities = 57/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%) Frame = +3 Query: 18 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197 + ++ K KV ITGAA G+GE++ R + G + I D+ E G+++ A++ ++ G Sbjct: 1 MSVNDSLKGKVAIITGAAQGLGEAIAREFVARGAA-VIITDVQREEGEAVAADILAQ-GG 58 Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNV 359 K F DV D E + ++ + G +DV++NNA L+ + I ++ + VNV Sbjct: 59 KALFIAHDVGDAEAWDVVVAKALDTFGKVDVLVNNAGLIQFAPLEEMPIEMFDRVTRVNV 118 Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGR 536 KAI K +G GG +IN+SS+ + Q+ + Y +K AV + + Sbjct: 119 RGPWLG-CKAILPALKAAG--GGAIINMSSMNGMIAQNPGLSAYATSKGAVRMLTKAVA- 174 Query: 537 PEHFSKTGVRVLTV 578 + + + GVRV +V Sbjct: 175 -QDYVQYGVRVNSV 187 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 72.5 bits (170), Expect = 8e-12 Identities = 54/199 (27%), Positives = 96/199 (48%), Gaps = 7/199 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGQSLQAELNSKYGNKTKFYR 215 K+K V +TGAA G+G + L +G ++ + D+ AE+ +S+Q + ++ Sbjct: 23 KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 389 DVT E+ ++ V G +DV+INNA + + D + I + + + Sbjct: 80 CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139 Query: 390 IEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN--CIGRPEHFSKT 557 +I GK + GKGG +IN+SS+ AL + ++ Y +K + Q +N +G H Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPH---- 195 Query: 558 GVRVLTVCLGATDTALLTD 614 +RV + G T ++ D Sbjct: 196 NIRVCGIGPGTILTDMVAD 214 >UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Rep: RH03309p - Drosophila melanogaster (Fruit fly) Length = 247 Score = 72.5 bits (170), Expect = 8e-12 Identities = 53/204 (25%), Positives = 99/204 (48%), Gaps = 13/204 (6%) Frame = +3 Query: 36 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215 W + V +TGA++GIG ++ R L+ GV +A+ + Q L+ EL ++ + + Sbjct: 4 WHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQ-LREELPQDRRSRLRIMQ 62 Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 377 DV+D + +AV + G +D++INNA L+ S+ ++ ++ NV ++ Sbjct: 63 CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYC 122 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP-------IYFATKSAVLQFSNCIGR 536 T +A E M + G V+ ++S+ + +P +Y ATK A+ + + Sbjct: 123 TQRAFESMRQRQ--SKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQ 180 Query: 537 PEHFSKTGVRVLTVCLGATDTALL 608 KT V+V ++ G DT L+ Sbjct: 181 EMRDFKTKVKVTSISPGLVDTELV 204 >UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms|Rep: Oxidoreductase - Halobacterium salinarium (Halobacterium halobium) Length = 260 Score = 72.5 bits (170), Expect = 8e-12 Identities = 58/200 (29%), Positives = 91/200 (45%), Gaps = 6/200 (3%) Frame = +3 Query: 30 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 209 HE V +TGA++GIGE+ L EG + A+E +L + G+ Sbjct: 16 HELAGDVAIVTGASSGIGEATAEALAAEGAHVVLAARRADELA-ALADRIEDTDGDAL-V 73 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALI 371 +D+TD++ +++ V E G ID+++NNA +M ++ +EVN+ L+ Sbjct: 74 VPTDITDDDAIDDLVSETVDEYGRIDILVNNAGVMLLEPLERADRSNLRQMVEVNLLGLM 133 Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551 T + IM G V+NVSSVA Y ATK V F++ I + + Sbjct: 134 NLTHAVVPIMQDQDAGH---VVNVSSVAGRQADADSSGYNATKFGVNAFTDAI--RQELT 188 Query: 552 KTGVRVLTVCLGATDTALLT 611 +R + GA DT L T Sbjct: 189 SQDIRTTIIEPGAVDTELST 208 >UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase - Mycobacterium bovis Length = 260 Score = 72.5 bits (170), Expect = 8e-12 Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 6/200 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS KV ++G A G+G S VR ++ EG K + DI +E G+++ AEL + Sbjct: 1 MSGRLIGKVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAA 55 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 365 ++ DVT + ++ V GG+ V++NNA ++N ++ +++ ++VN+T Sbjct: 56 RYVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTG 115 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 + ++ M K +G G++IN+SS+ L + Y ATK AV + Sbjct: 116 VFLGIRAVVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--E 170 Query: 546 FSKTGVRVLTVCLGATDTAL 605 +G+RV ++ G T + Sbjct: 171 LGPSGIRVNSIHPGLVKTPM 190 >UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 240 Score = 72.1 bits (169), Expect = 1e-11 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 4/152 (2%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQ---AELNSKYGN-KTKF 209 +KV +T GIG S + L +++A+LD+ + + L ++G K + Sbjct: 5 NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62 Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389 Y +V + E F + VV+ +G +D+++ NAA+ D+ I+VN+ +I TL A Sbjct: 63 YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120 Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 485 +E MG H KGG V+N++S L + + + Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGLEHNKFLGV 152 >UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n=11; Proteobacteria|Rep: D-beta-hydroxybutyrate dehydrogenase - Bradyrhizobium japonicum Length = 249 Score = 72.1 bits (169), Expect = 1e-11 Identities = 50/193 (25%), Positives = 91/193 (47%), Gaps = 4/193 (2%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 K V +TGAA+G+G + R+ EG ++A+ D E+ S+ E+ + G K ++ Sbjct: 2 KGLTVLVTGAASGMGRATARVFAAEGA-NVAVTDYDEQGAISVAKEIAAS-GGSAKAWKL 59 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG--IYKKAIEVNVTALITSTLKA 389 DV D +++ V GG+D+V+NNA + + +I Y+ A + ++T+ + Sbjct: 60 DVADGGEIKRVVHDVAAHFGGLDIVVNNAGISVRVAIDDETYEDAWARGIAVMLTAHPRI 119 Query: 390 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 I H K ++N++S AL + + Y A K V + + + G+ Sbjct: 120 IRAALPHLRKSKSPRIVNIASTEALGATALHSPYSAAKGGVASLTRSLA--VELGREGIT 177 Query: 567 VLTVCLGATDTAL 605 V +C G TA+ Sbjct: 178 VNCICPGPIRTAI 190 >UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 249 Score = 72.1 bits (169), Expect = 1e-11 Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 5/191 (2%) Frame = +3 Query: 51 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230 V +TGA TGIG + +G ++ + EEAGQSL AEL + G K +F ++DV + Sbjct: 6 VLVTGALTGIGRATAIAFAKQGA-NVVVSGRREEAGQSLAAELRT-LGAKAEFIKADVAN 63 Query: 231 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 410 E ++ V G +D+ INNA ++G + NV A ++ + + KH Sbjct: 64 EAEVRSLVEKAVSLFGQLDIAINNAG-TEGALGPITEQSTENVHATFSTNVLGTLLSMKH 122 Query: 411 S----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575 +G G+++N+SS+A +Y A+K AV + + GVRV Sbjct: 123 EIRAMQAQGHGSIVNLSSIAGKVGMAGASVYVASKHAVEGLTKSAAL--EGAAFGVRVNA 180 Query: 576 VCLGATDTALL 608 V G T +L Sbjct: 181 VAPGPVQTDML 191 >UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 256 Score = 72.1 bits (169), Expect = 1e-11 Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 7/190 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 KD+ VFI+G ATGIG ++V +G K A +D+ E+AG +L L +K G +F Sbjct: 13 KDRSVFISGGATGIGAAIVEAYAKQGAK-TAFVDLDEKAGTALAKRL-TKDGYDVRFEVC 70 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 386 D+TD + + + A + G I V++NNAA ND + E L+ +K Sbjct: 71 DITDIQDYQSKIRAAAEVFGPITVLLNNAA--NDVRHSLESLTEERFDELVGVNIKHAMF 128 Query: 387 ---AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 A+ M + G GG++IN SV + + P Y +K+A + + R Sbjct: 129 AAQAVAPMMRKLG--GGSIINFGSVGWMMATAGYPTYGTSKAATHGLTRSLAR--DLGGF 184 Query: 558 GVRVLTVCLG 587 G+RV T+ G Sbjct: 185 GIRVNTLVPG 194 >UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 273 Score = 72.1 bits (169), Expect = 1e-11 Identities = 57/196 (29%), Positives = 95/196 (48%), Gaps = 8/196 (4%) Frame = +3 Query: 57 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELN-SKYGNKTKFYRSDVTDE 233 +TGAA+GIG ++ LL + + DI EA + A + G + DV D Sbjct: 7 VTGAASGIGRALCERLLTDKGNQVCACDINYEALTQIYANHKLADAGGSLILRQLDVRDV 66 Query: 234 EHFLGILNAVVQEQGGIDVVINNAALMNDS----IGIYKKA---IEVNVTALITSTLKAI 392 + + ++N V+ + IDV+ N A ++ D+ I + ++NV I T + Sbjct: 67 QQWQEVVNTVIAQWQRIDVMCNIAGVLKDNWIADIALPDDVDLHFDINVKGTIFGTQSVV 126 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 + M ++ G G +INV+S+AAL+ + +Y A+K AV +S G K G+ V Sbjct: 127 DTM-RNQGS--GHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAGM--ELEKYGIAVT 181 Query: 573 TVCLGATDTALLTDEK 620 T+C A T +L +K Sbjct: 182 TLCPDAVQTPMLDQQK 197 >UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mycobacterium gilvum PYR-GCK|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium gilvum PYR-GCK Length = 260 Score = 72.1 bits (169), Expect = 1e-11 Identities = 55/199 (27%), Positives = 99/199 (49%), Gaps = 9/199 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K V ITGAA+GIG + ++++ EG + + I D+ +A + +++ G ++V Sbjct: 9 KRVVITGAASGIGRAAAQLMIGEGAR-VLIADLDADAAAAAASDI----GGNAIGVAANV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA---------LMNDSIGIYKKAIEVNVTALITS 377 D++ +++ V E GGIDV+ N+ L+ + + +A+ +N + + + Sbjct: 64 LDDKSVAAMIDRAVTEFGGIDVLCNHVGGSNPHKDLDLLRLDLDEWDRAMALNARSTVVA 123 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + A+ M GG ++IN SVA LT + Y A+K+AV++ + I + + Sbjct: 124 SRLALPHMIAEGGG---SIINTVSVAGLTGDTLQCAYGASKAAVIRLTQYIA--TQYGRK 178 Query: 558 GVRVLTVCLGATDTALLTD 614 GVR V GA T L D Sbjct: 179 GVRCNAVAPGAVMTPALAD 197 >UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2; Actinobacteria (class)|Rep: Putative short chain dehydrogenase - marine actinobacterium PHSC20C1 Length = 265 Score = 72.1 bits (169), Expect = 1e-11 Identities = 56/192 (29%), Positives = 90/192 (46%), Gaps = 6/192 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 M+H K++ V ITG +GIG + + G + + + D++ A +S+ E+ G+ Sbjct: 1 MTHPLKNQTVLITGGGSGIGRLLALGAAERGAR-VVVWDLSAAAAESVCEEILGA-GHHA 58 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 365 + + DV+D +NA ++ G +DV+INNA L++ S ++ I VN A Sbjct: 59 EAFTVDVSDRN----AVNAAAKKTGQVDVLINNAGIVTGKNLLDASDEAIERTIRVNTLA 114 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 L T +G + GTV+ +SS A L Y A+K A L F+ + Sbjct: 115 LFWVTRA---FLGNMIANRRGTVVTISSAAGLVGVAKQTDYSASKFAALGFAESLRVELS 171 Query: 546 FSKTGVRVLTVC 581 TGV L VC Sbjct: 172 KENTGVNSLVVC 183 >UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep: Acetoin reductases - Mycobacterium sp. (strain KMS) Length = 285 Score = 72.1 bits (169), Expect = 1e-11 Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 9/194 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGA GIG + L +G IA++D++E AE+ S+ G+KT + +DV Sbjct: 27 KVALVTGAGRGIGRGIAVELARQGAD-IALVDVSEAGLPDAAAEI-SEIGSKTTTFVADV 84 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGIYKKAI----EVNVTAL---ITS 377 D + ++ GG DV++NNA AL+ + + + +NV + I + Sbjct: 85 RDRDAVFAAVDHAAAALGGFDVMVNNAGIALVGPIAEVTAEDLARLWAINVDGVLWGIQA 144 Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + +G H+ GK +IN SS+A ++ Y ATK AV + + ++ Sbjct: 145 AAAKFKELGNHAEGKVSKIINASSIAGHEGFAMLGPYSATKFAVRALTQAAAK--EYAAD 202 Query: 558 GVRVLTVCLGATDT 599 G+ V C G T Sbjct: 203 GITVNAYCPGVVGT 216 >UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella woodyi ATCC 51908 Length = 255 Score = 72.1 bits (169), Expect = 1e-11 Identities = 49/185 (26%), Positives = 94/185 (50%), Gaps = 6/185 (3%) Frame = +3 Query: 51 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230 VFITG A+GIG ++VR +++G ++ +D +AG++L L+ G + F+ DVTD Sbjct: 15 VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73 Query: 231 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 392 + ++ Q+ G +D++INN +D+ G+ +K+ + +N+ + ++ A Sbjct: 74 TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133 Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572 +M + K G +IN SS A M Y K+ + + + + + ++ VRV Sbjct: 134 LVMKQR---KQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAK--DYGESRVRVN 188 Query: 573 TVCLG 587 + G Sbjct: 189 AIVPG 193 >UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep: Os07g0665000 protein - Oryza sativa subsp. japonica (Rice) Length = 310 Score = 72.1 bits (169), Expect = 1e-11 Identities = 52/209 (24%), Positives = 98/209 (46%), Gaps = 9/209 (4%) Frame = +3 Query: 6 IYGTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS 185 ++ + S + KV ITGAA+GIGE+ + + G K + I DI ++ G+++ AEL + Sbjct: 33 LFSSSSSSRKLDGKVAVITGAASGIGEATAKEFVRNGAK-VIIADIQDDLGRAVAAELGA 91 Query: 186 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND---------SIGIYK 338 + + DVT E+ ++ V G +DVV +NA ++ + Y Sbjct: 92 ---DAASYTHCDVTVEKDVAAAVDLAVARHGRLDVVYSNAGVIGAPAPASLAALDLDEYD 148 Query: 339 KAIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQF 518 + + VN +++ A +M + G ++ +S AA+ P+Y +K+A++ Sbjct: 149 RVMAVNARSMLACVKHAARVMAPR---RAGCILCTASSAAVLGGVASPVYSMSKAAIVGM 205 Query: 519 SNCIGRPEHFSKTGVRVLTVCLGATDTAL 605 + R ++ GVRV + A T + Sbjct: 206 VRAVAR--QLARDGVRVNAISPHAIPTPM 232 >UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 387 Score = 72.1 bits (169), Expect = 1e-11 Identities = 51/185 (27%), Positives = 94/185 (50%), Gaps = 17/185 (9%) Frame = +3 Query: 78 IGESVVRILLDEGVKHIAILDIAEEAGQ---SLQAELNSKYGNK-----TKFYRSDVTDE 233 IG+++ L ++G+ + ++D +EE G+ SL + N+K+ K F R DVT+ Sbjct: 36 IGKAISLALGEKGI-FVTVVDFSEEGGKEVASLVEKENAKFHPKLGFPSAMFIRCDVTNT 94 Query: 234 EHFLGILNAVVQEQGGIDVVINNAAL---------MNDSIGIYKKAIEVNVTALITSTLK 386 + GG+D+ +N+A + ++ G++++ I VN+ A+I T Sbjct: 95 RELAAAFKKHLATYGGLDICVNSAGIGTHEPFHKDQTENSGLWRRTINVNLVAVIDCTRL 154 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 AI+ M + K G +IN+ S + L +V PIY A+K V+ F+ + + + G+R Sbjct: 155 AIQTM--QAAKKPGVIINMGSASGLYPMYVDPIYSASKGGVVLFTRSLA---PYKRHGIR 209 Query: 567 VLTVC 581 V +C Sbjct: 210 VNVLC 214 >UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Oligohymenophorea|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 260 Score = 72.1 bits (169), Expect = 1e-11 Identities = 55/204 (26%), Positives = 101/204 (49%), Gaps = 18/204 (8%) Frame = +3 Query: 48 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSDV 224 V +TG +G+GE+ V LL++GV+ + I D EE G +Q +KYG ++ +F + DV Sbjct: 8 VALVTGGTSGLGEATVYALLEKGVR-VFIADRNEEKGLQIQ----TKYGQDRCRFQKCDV 62 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------------YKKAIEVNVTA 365 +DE +++A V G I +++N+A +++ + + + + VNV Sbjct: 63 SDEAQVKALVDACVATFGAIHILLNSAGVISAGLIVGGKNQDQTIKTEEMNRVLGVNVVG 122 Query: 366 LITST----LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533 T L+ ++ + + G ++NV+SVA + +Y A+K A++ + + Sbjct: 123 TFNVTKYVALQMVKQQPLNEFKERGVIVNVASVAGIEGQRGQTVYAASKGAIIGMTLPLA 182 Query: 534 RPEHFSKTGVRVLTVCLGATDTAL 605 R K GVRV T+ G T + Sbjct: 183 R--DLGKFGVRVCTIAPGIFQTPM 204 >UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase - Oceanobacillus iheyensis Length = 244 Score = 71.7 bits (168), Expect = 1e-11 Identities = 57/197 (28%), Positives = 99/197 (50%), Gaps = 6/197 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 ++KV ITG A G+G S VR+ EG K + D+ EE G +L EL G KF + Sbjct: 5 ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 380 DVT+ + + +++ + G ++V++NNA LM + Y+K I++N ++ Sbjct: 60 DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 +KA+ + +G G+++N+SS+ + V Y +K AV + G Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAVG--YTDSKFAVRGATKAAA--VQLGGLG 172 Query: 561 VRVLTVCLGATDTALLT 611 +RV +V G +T ++T Sbjct: 173 IRVNSVHPGVIETPMVT 189 >UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 286 Score = 71.7 bits (168), Expect = 1e-11 Identities = 48/181 (26%), Positives = 88/181 (48%), Gaps = 6/181 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 + F+TG GIG ++ I L E ++AILDI E + + G + + +DV Sbjct: 10 QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 386 + + ++ G +D+++NNA + S +K I++N+ +++ +T Sbjct: 68 MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A M +GGKGG++INV+S+ A + +Y A K+ + F+ + S G+R Sbjct: 128 AARHMV--AGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMAL--ELSGHGIR 183 Query: 567 V 569 V Sbjct: 184 V 184 >UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 274 Score = 71.7 bits (168), Expect = 1e-11 Identities = 55/200 (27%), Positives = 100/200 (50%), Gaps = 6/200 (3%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS ++ KV +TG +GIG +V LL G + ++ +E+ + + Y N T Sbjct: 1 MSDVFEGKVAIVTGGTSGIGYAVSEELLKRGAT-VWVIGSRQESVDKARKSF-AAYKN-T 57 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MND-----SIGIYKKAIEVNVTA 365 +F DVT + G+++A V++ G +D + NNA + M ++ ++++AI++N+ Sbjct: 58 RFLAVDVTVADQVKGMIDACVEKDGRLDYLFNNAGIGMTHPSQYLTLEMWQQAIDLNLWG 117 Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 ++ A+ +M K G ++N SS+A + Y ATK AV + + R E Sbjct: 118 VVYGVHFALPVM---LAQKSGHIVNTSSIAGIVPLPSQAAYCATKHAVTALTESL-RYEF 173 Query: 546 FSKTGVRVLTVCLGATDTAL 605 F + G+ T+C TA+ Sbjct: 174 FEE-GIAFTTICPSNVATAI 192 >UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteobacteria|Rep: Acetoacetyl-CoA reductase - Acinetobacter sp. (strain RA3849) Length = 248 Score = 71.7 bits (168), Expect = 1e-11 Identities = 50/197 (25%), Positives = 90/197 (45%), Gaps = 6/197 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 + KV +TGA GIG + R L+ G K IA + EE + + + +F + Sbjct: 3 EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 380 D+ + E + + +G +DV++NNA + D S + + I+ N+ L T T Sbjct: 63 DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + K K G ++N+SSV L Y A+K+ ++ F+ + + +++ Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALA--QEGARSN 177 Query: 561 VRVLTVCLGATDTALLT 611 + V V G T T ++T Sbjct: 178 ICVNVVAPGYTATPMVT 194 >UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member 10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR family member 10 - Homo sapiens (Human) Length = 270 Score = 71.7 bits (168), Expect = 1e-11 Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 383 T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 Query: 384 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176 Query: 561 VRVLTVCLGATDTAL 605 VRV + G T L Sbjct: 177 VRVNCISPGNIWTPL 191 >UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cellular organisms|Rep: Acetoin(diacetyl) reductase - Klebsiella pneumoniae Length = 256 Score = 71.7 bits (168), Expect = 1e-11 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 6/193 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGA GIG+++ L+ +G +AI D + +++ +E+N G + + DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 386 +D + + + GG DV++NNA + +SI I K +NV +I Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566 A+E K G GG +IN S A + + +Y ++K AV + R + G+ Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176 Query: 567 VLTVCLGATDTAL 605 V C G T + Sbjct: 177 VNGYCPGIVKTPM 189 >UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinobacter algicola DG893|Rep: Short chain dehydrogenase - Marinobacter algicola DG893 Length = 252 Score = 71.3 bits (167), Expect = 2e-11 Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 7/166 (4%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV +TGA IGE V R+L EG IA++D+ + + A++ + G + K + DV Sbjct: 6 KVAIVTGAGRNIGEEVSRVLSAEGAT-IAVVDLDRSRAEKVAADIVAS-GGQAKPFICDV 63 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-KAIEVNVTALITSTLK----- 386 E+ + AVV + GG+D+++NN A M+D+ I+ A E N T IT T Sbjct: 64 ASEDQIRATVAAVVDQLGGLDILVNNVA-MSDNKHIFDITAEEWNRTLAITLTAPFLFGK 122 Query: 387 -AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 521 A + M +H+ G +INVSS + Y A K V+ + Sbjct: 123 YAAQAMVQHAA--DGRIINVSSTSGYYGRDRAIAYTAAKGGVINLT 166 >UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Pedobacter sp. BAL39|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Pedobacter sp. BAL39 Length = 248 Score = 71.3 bits (167), Expect = 2e-11 Identities = 56/198 (28%), Positives = 95/198 (47%), Gaps = 9/198 (4%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 +KV ITGAA G+GES R + EG K + + D++ EAGQ L EL G F + D Sbjct: 6 NKVAIITGAAQGMGESHARTFVAEGAK-VILTDVSAEAGQKLADEL----GENAIFIKHD 60 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITST 380 VT E + ++ + G ++V++NNA ++ + Y K ++N ++ Sbjct: 61 VTCSEQWAHVVAEAEKAFGHVNVLVNNAGILGPMVKTQELQEADYLKVCDINQHSVFYGM 120 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCIGRPEHFSK 554 I M K G+++N+SS+A + ++ P Y A+K AV + + + Sbjct: 121 KAVIPSMIK---AGIGSIVNISSIAGIVANYGFPSLAYVASKFAVRGMTKATA--IEYGE 175 Query: 555 TGVRVLTVCLGATDTALL 608 +RV +V G T ++ Sbjct: 176 KNIRVNSVHPGFIKTPMM 193 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 71.3 bits (167), Expect = 2e-11 Identities = 62/216 (28%), Positives = 109/216 (50%), Gaps = 13/216 (6%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 KV ITG++ GIG+++ + L ++G + + I +EA + E + G T + Sbjct: 12 KVAVITGSSKGIGKAIAKGLAEQGAQ-VVISSRNQEACDEVAKEFKEQ-GLDTIGIACHI 69 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG--------IYKKAIEVNVTALITST 380 E+ +++ ++ G ID+++NNAA+ N G I+ K ++VNV A + Sbjct: 70 GKEDQRKNLVDKTIESFGRIDILVNNAAI-NPVFGPIEEVSPEIFDKIMDVNVKA--PWS 126 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 L + ++ K G++IN++SV ALT + IY +K+A+L + + + + K G Sbjct: 127 LSNL-VLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTK--NQAKEWGKYG 183 Query: 561 VRVLTVCLGATDT----ALLTDEK-LGTFDKYLXSS 653 V+ +C G T AL +EK L +K L SS Sbjct: 184 VKANAICPGLIKTKFSAALWQNEKILSKVEKALPSS 219 >UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 253 Score = 71.3 bits (167), Expect = 2e-11 Identities = 53/196 (27%), Positives = 90/196 (45%), Gaps = 5/196 (2%) Frame = +3 Query: 33 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212 ++ KVV ITG ATGIG + +G + + + D+ + A ++++ L + G F Sbjct: 6 DFTGKVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAETVR--LIEESGGTALFV 62 Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392 R+DVT ++ V GG+ V NNA ++ + G + E + I LK + Sbjct: 63 RTDVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGV 121 Query: 393 EIMGKH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557 + K+ + GG++IN +SVA + M Y A K V+ + ++ Sbjct: 122 FLALKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAA--IDYAAA 179 Query: 558 GVRVLTVCLGATDTAL 605 GVRV + G DT + Sbjct: 180 GVRVNALAPGLVDTPM 195 >UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sp. (strain ANA-3) Length = 253 Score = 71.3 bits (167), Expect = 2e-11 Identities = 59/206 (28%), Positives = 95/206 (46%), Gaps = 8/206 (3%) Frame = +3 Query: 42 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221 +K +TGAA GIG++++R LL EG + +A A+ + +L+ N +K + D Sbjct: 5 NKTAVVTGAAGGIGQAIIRKLLAEGARVVA----ADLSADALKV-FNDFPADKLVTFSVD 59 Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITST 380 VTD + ++ + G +D++INNA L +D I ++ VN + Sbjct: 60 VTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGI 119 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 L + G G ++N SSV A S + Y +K+AV + C + G Sbjct: 120 LAGGRQF--QAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAAL--ELAPLG 175 Query: 561 VRVLTVCLGATDTALLTD-EKLGTFD 635 VRV V G DT +L E LG ++ Sbjct: 176 VRVCAVAPGRVDTPMLRQYEALGLWE 201 >UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyces parvulus|Rep: Putative ketoreductase - Streptomyces parvulus Length = 265 Score = 70.9 bits (166), Expect = 2e-11 Identities = 58/201 (28%), Positives = 92/201 (45%), Gaps = 6/201 (2%) Frame = +3 Query: 24 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203 MS E D+V+ +TGA +GIG + R+L+ G + + ++ E A A L S + Sbjct: 1 MSLELTDRVMMVTGAGSGIGRAAARLLVGHGAR-VVLVGRTESALTETTAGLPSSH---H 56 Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383 DV D++ + V G +D NNA S G + N +I + L Sbjct: 57 LVVPCDVGDDKQVADCVARAVSRFGRLDGAFNNAGTFG-SFGPLHQDTADNFDRVIATNL 115 Query: 384 KAI------EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545 + + +I + G GG ++N +SVA P+Y ATK AV+ S + Sbjct: 116 RGVWSCMRGQIEAMLTAG-GGAIVNCASVAGHIGHAQSPLYSATKHAVIGLSKSVAL--Q 172 Query: 546 FSKTGVRVLTVCLGATDTALL 608 ++ G+RV V G+TDT +L Sbjct: 173 YAGDGIRVNVVSPGSTDTPML 193 >UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Flavobacteriales bacterium HTCC2170 Length = 245 Score = 70.9 bits (166), Expect = 2e-11 Identities = 54/196 (27%), Positives = 93/196 (47%), Gaps = 6/196 (3%) Frame = +3 Query: 39 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218 KDK+ +TG A GIG++V + EG + I+D+ + GQ++ AE G K +++ Sbjct: 4 KDKIAVVTGGARGIGQAVSELFAKEGAT-VIIMDLLPQ-GQAV-AEGIIASGGKAEYHSL 60 Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 380 VT++ G+ ++V + G ID++INNA + D S + IEVN+ + T Sbjct: 61 SVTNKSDVEGVFSSVNDKYGKIDILINNAGITRDRTLEKMSEAEWDAVIEVNLKGVFICT 120 Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560 + M K G +++ +S L + Y ATK+ V+ + F K G Sbjct: 121 QAVVPYM---KASKYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMAKT--WTVEFGKYG 175 Query: 561 VRVLTVCLGATDTALL 608 + + G T T ++ Sbjct: 176 ITANAIAPGFTMTDMV 191 >UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 261 Score = 70.9 bits (166), Expect = 2e-11 Identities = 49/194 (25%), Positives = 93/194 (47%), Gaps = 7/194 (3%) Frame = +3 Query: 45 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224 K ITGAA GIG ++ + + EG H+ + DI++ G+ A+L + G+ + DV Sbjct: 7 KTAVITGAADGIGHAIAQAMAREGA-HVFLSDISDAQGERCAAQLRAA-GHLADYLHCDV 64 Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383 + +++ V++ G +DV++NNAA+ + + +++ IE+N+T++ Sbjct: 65 AKADDIARLVDTAVRQTGHLDVMVNNAAIAIGGMPVHEMTDEQWQRLIEINLTSVFRGCK 124 Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563 A+ M K G++IN++S Y K AV+ + + F + Sbjct: 125 CALPHM---IAQKSGSIINMASAQGHIGLDGWTAYAGAKGAVMAMTRQMA--VEFGPVNI 179 Query: 564 RVLTVCLGATDTAL 605 RV ++ G DT + Sbjct: 180 RVNSISPGTIDTPM 193 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 630,794,034 Number of Sequences: 1657284 Number of extensions: 12539209 Number of successful extensions: 44893 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 40596 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 42256 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 50000004659 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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