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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV10n04f
         (659 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo...   178   1e-43
UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne...   158   1e-37
UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R...   153   3e-36
UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy...   147   2e-34
UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a...   142   7e-33
UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a...   142   9e-33
UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy...   141   1e-32
UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a...   140   4e-32
UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a...   137   3e-31
UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a...   132   7e-30
UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a...   132   7e-30
UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy...   130   2e-29
UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy...   129   7e-29
UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a...   127   3e-28
UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a...   126   4e-28
UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori...   125   1e-27
UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R...   124   1e-27
UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [...   122   6e-27
UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a...   121   2e-26
UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|...   120   2e-26
UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy...   120   3e-26
UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro...   120   3e-26
UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,...   114   2e-24
UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a...   107   3e-22
UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881...   106   5e-22
UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy...   103   5e-21
UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact...   101   2e-20
UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans...    98   1e-19
UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ...    96   6e-19
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR...    96   8e-19
UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor...    95   1e-18
UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    95   2e-18
UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve...    94   2e-18
UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim...    92   1e-17
UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam...    91   2e-17
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O...    91   3e-17
UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb...    90   4e-17
UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    90   5e-17
UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit...    89   1e-16
UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    89   1e-16
UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:...    88   2e-16
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR...    88   2e-16
UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR...    88   2e-16
UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena...    87   3e-16
UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR...    87   4e-16
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b...    87   4e-16
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu...    87   5e-16
UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR...    85   1e-15
UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro...    85   1e-15
UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR...    85   1e-15
UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=...    85   1e-15
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR...    85   2e-15
UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb...    84   2e-15
UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re...    84   3e-15
UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR...    84   3e-15
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta...    83   4e-15
UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr...    83   4e-15
UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc...    83   6e-15
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR...    83   6e-15
UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR...    83   6e-15
UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re...    83   6e-15
UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil...    83   6e-15
UniRef50_Q28GY1 Cluster: Novel protein containing short chain de...    83   8e-15
UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    83   8e-15
UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=...    82   1e-14
UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel...    82   1e-14
UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    81   2e-14
UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom...    81   2e-14
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena...    81   2e-14
UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR...    81   2e-14
UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei...    81   2e-14
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte...    81   2e-14
UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li...    81   2e-14
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr...    81   2e-14
UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ...    81   3e-14
UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena...    81   3e-14
UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill...    81   3e-14
UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR...    81   3e-14
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR...    81   3e-14
UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR...    80   4e-14
UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas...    80   4e-14
UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;...    80   4e-14
UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR...    80   4e-14
UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    80   5e-14
UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep...    80   5e-14
UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    79   7e-14
UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All...    79   9e-14
UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ...    79   9e-14
UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc...    79   9e-14
UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri...    79   9e-14
UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD...    79   9e-14
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho...    79   9e-14
UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR...    79   9e-14
UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR...    79   9e-14
UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR...    79   9e-14
UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena...    79   9e-14
UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    79   1e-13
UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K...    79   1e-13
UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n...    79   1e-13
UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR...    79   1e-13
UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re...    79   1e-13
UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR...    79   1e-13
UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=...    79   1e-13
UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;...    79   1e-13
UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb...    79   1e-13
UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase...    78   2e-13
UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;...    78   2e-13
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...    78   2e-13
UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    78   2e-13
UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena...    78   2e-13
UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    78   2e-13
UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;...    78   2e-13
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    77   3e-13
UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR...    77   3e-13
UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=...    77   3e-13
UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc...    77   4e-13
UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena...    77   4e-13
UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or...    77   4e-13
UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena...    77   5e-13
UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o...    77   5e-13
UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta...    77   5e-13
UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR...    77   5e-13
UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion...    77   5e-13
UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ...    77   5e-13
UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici...    77   5e-13
UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -...    76   7e-13
UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    76   7e-13
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai...    76   7e-13
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K...    76   7e-13
UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR...    76   7e-13
UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR...    76   7e-13
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    76   7e-13
UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob...    76   7e-13
UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR...    76   7e-13
UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam...    76   7e-13
UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote...    76   9e-13
UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car...    76   9e-13
UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    76   9e-13
UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR...    76   9e-13
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    76   9e-13
UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap...    75   1e-12
UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    75   1e-12
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1...    75   1e-12
UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba...    75   1e-12
UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena...    75   1e-12
UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...    75   1e-12
UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici...    75   1e-12
UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc...    75   1e-12
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill...    75   2e-12
UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro...    75   2e-12
UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ...    75   2e-12
UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    75   2e-12
UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu...    75   2e-12
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;...    75   2e-12
UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta...    75   2e-12
UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|...    75   2e-12
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo...    74   3e-12
UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena...    74   3e-12
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ...    74   3e-12
UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p...    74   4e-12
UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    74   4e-12
UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p...    74   4e-12
UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2...    74   4e-12
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ...    74   4e-12
UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ...    74   4e-12
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster...    74   4e-12
UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    74   4e-12
UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=...    73   5e-12
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc...    73   5e-12
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=...    73   5e-12
UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR...    73   5e-12
UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte...    73   5e-12
UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR...    73   5e-12
UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    73   5e-12
UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;...    73   5e-12
UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd...    73   5e-12
UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000...    73   6e-12
UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R...    73   6e-12
UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    73   6e-12
UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR...    73   6e-12
UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena...    73   6e-12
UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR...    73   6e-12
UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR...    73   6e-12
UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr...    73   6e-12
UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac...    73   6e-12
UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;...    73   6e-12
UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo...    73   6e-12
UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    73   8e-12
UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ...    73   8e-12
UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    73   8e-12
UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac...    73   8e-12
UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re...    73   8e-12
UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms...    73   8e-12
UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh...    73   8e-12
UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a...    72   1e-11
UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n...    72   1e-11
UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2...    72   1e-11
UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:...    72   1e-11
UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:...    72   1e-11
UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ...    72   1e-11
UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena...    72   1e-11
UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n...    72   1e-11
UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo...    72   1e-11
UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb...    72   1e-11
UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell...    72   1e-11
UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob...    71   2e-11
UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    71   2e-11
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena...    71   2e-11
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc...    71   2e-11
UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    71   2e-11
UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas...    71   2e-11
UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep...    71   2e-11
UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio...    71   2e-11
UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr...    71   3e-11
UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena...    71   3e-11
UniRef50_Q0B2G1 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ...    71   3e-11
UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom...    71   3e-11
UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006...    71   3e-11
UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=...    71   3e-11
UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc...    70   4e-11
UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    70   4e-11
UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3...    70   4e-11
UniRef50_Q13GX3 Cluster: Putative short-chain dehydrogenase/redu...    70   4e-11
UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR...    70   4e-11
UniRef50_A6T789 Cluster: Putative short-chain dehydrogenase/redu...    70   4e-11
UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ...    70   4e-11
UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob...    70   4e-11
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro...    70   4e-11
UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ...    70   4e-11
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=...    70   4e-11
UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ...    70   4e-11
UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    70   6e-11
UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc...    70   6e-11
UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas...    70   6e-11
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    70   6e-11
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    70   6e-11
UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena...    70   6e-11
UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A0XX22 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    70   6e-11
UniRef50_Q9VYU9 Cluster: CG9360-PA; n=12; Diptera|Rep: CG9360-PA...    70   6e-11
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;...    70   6e-11
UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh...    70   6e-11
UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ...    69   8e-11
UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    69   8e-11
UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu...    69   8e-11
UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR...    69   8e-11
UniRef50_Q1IP02 Cluster: Short-chain dehydrogenase/reductase SDR...    69   8e-11
UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena...    69   8e-11
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec...    69   8e-11
UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR...    69   8e-11
UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    69   8e-11
UniRef50_UPI0000DB6B86 Cluster: PREDICTED: similar to CG9360-PA;...    69   1e-10
UniRef50_UPI000050F9D4 Cluster: COG1028: Dehydrogenases with dif...    69   1e-10
UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif...    69   1e-10
UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici...    69   1e-10
UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena...    69   1e-10
UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu...    69   1e-10
UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ...    69   1e-10
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena...    69   1e-10
UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb...    69   1e-10
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc...    69   1e-10
UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu...    69   1e-10
UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n...    69   1e-10
UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14...    69   1e-10
UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr...    69   1e-10
UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    69   1e-10
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre...    69   1e-10
UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...    69   1e-10
UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    69   1e-10
UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi...    69   1e-10
UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f...    69   1e-10
UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati...    69   1e-10
UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ...    69   1e-10
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc...    69   1e-10
UniRef50_A1T7K9 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam...    69   1e-10
UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q6IDG8 Cluster: RH36352p; n=2; Drosophila melanogaster|...    69   1e-10
UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve...    69   1e-10
UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;...    69   1e-10
UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000...    68   2e-10
UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    68   2e-10
UniRef50_Q930L5 Cluster: Putative; n=3; Proteobacteria|Rep: Puta...    68   2e-10
UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas...    68   2e-10
UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll...    68   2e-10
UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ...    68   2e-10
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid...    68   2e-10
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R...    68   2e-10
UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac...    68   2e-10
UniRef50_Q3S8D5 Cluster: Putative short-chain dehydrogenase/redu...    68   2e-10
UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida...    68   2e-10
UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    68   2e-10
UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe...    68   2e-10
UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;...    68   2e-10
UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C...    68   2e-10
UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa...    68   2e-10
UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat...    68   2e-10
UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula...    68   2e-10
UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13...    68   2e-10
UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    68   2e-10
UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R...    68   2e-10
UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|...    68   2e-10
UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill...    68   2e-10
UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc...    68   2e-10
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho...    68   2e-10
UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ...    68   2e-10
UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari...    68   2e-10
UniRef50_Q75DB1 Cluster: ABR248Wp; n=4; Eremothecium gossypii|Re...    68   2e-10
UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;...    68   2e-10
UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth...    68   2e-10
UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    67   3e-10
UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re...    67   3e-10
UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas...    67   3e-10
UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena...    67   3e-10
UniRef50_Q7UJY8 Cluster: Probable short-chain dehydrogenase; n=1...    67   3e-10
UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    67   3e-10
UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact...    67   3e-10
UniRef50_Q2IVE1 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    67   3e-10
UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma...    67   3e-10
UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2; Bacteri...    67   3e-10
UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    67   3e-10
UniRef50_A3JK09 Cluster: Oxidoreductase; n=1; Marinobacter sp. E...    67   3e-10
UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb...    67   3e-10
UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh...    67   3e-10
UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=...    67   3e-10
UniRef50_A4XEV7 Cluster: Short-chain dehydrogenase/reductase SDR...    44   4e-10
UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ...    67   4e-10
UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogena...    67   4e-10
UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...    67   4e-10
UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr...    67   4e-10
UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=...    67   4e-10
UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei...    67   4e-10
UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_A6C1M0 Cluster: Short chain dehydrogenase; n=1; Plancto...    67   4e-10
UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_A0YDM1 Cluster: Putative 3-ketoacyl-CoA reductase; n=3;...    67   4e-10
UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;...    67   4e-10
UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family memb...    67   4e-10
UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena...    66   5e-10
UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin...    66   5e-10
UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    66   5e-10
UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter...    66   5e-10
UniRef50_Q84EX5 Cluster: R-specific alcohol dehydrogenase; n=5; ...    66   5e-10
UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ...    66   5e-10
UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri...    66   5e-10
UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep...    66   5e-10
UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1...    66   5e-10
UniRef50_A5P5M1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_A4WBV4 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte...    66   5e-10
UniRef50_Q16Q07 Cluster: Alcohol dehydrogenase, putative; n=1; A...    66   5e-10
UniRef50_A0D0S7 Cluster: Chromosome undetermined scaffold_33, wh...    66   5e-10
UniRef50_Q0U1A7 Cluster: Putative uncharacterized protein; n=1; ...    66   5e-10
UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    66   5e-10
UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)...    66   7e-10
UniRef50_Q9RKB7 Cluster: Probable 3-oxoacyl-[acyl carrier protei...    66   7e-10
UniRef50_Q8UAB0 Cluster: Dehydrogenase; n=1; Agrobacterium tumef...    66   7e-10
UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    66   7e-10
UniRef50_Q2SKD5 Cluster: Short-chain dehydrogenase of various su...    66   7e-10
UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    66   7e-10
UniRef50_Q3W7K4 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot...    66   7e-10
UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protei...    66   7e-10
UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke...    66   7e-10
UniRef50_A3SL40 Cluster: Putative uncharacterized protein; n=1; ...    66   7e-10
UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein...    66   7e-10
UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;...    66   7e-10
UniRef50_Q6CFW0 Cluster: Yarrowia lipolytica chromosome B of str...    66   7e-10
UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=...    66   7e-10
UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro...    66   7e-10
UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya...    66   9e-10
UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei...    66   9e-10
UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    66   9e-10
UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_Q2S467 Cluster: NAD-binding domain 4, putative; n=1; Sa...    66   9e-10
UniRef50_Q2KXQ0 Cluster: Probable short chain dehydrogenase/redu...    66   9e-10
UniRef50_Q7P5A9 Cluster: Ketoacyl reductase hetN; n=3; Fusobacte...    66   9e-10
UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_Q1BF92 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_Q1AYC7 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh...    66   9e-10
UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ...    66   9e-10
UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo...    66   9e-10
UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei...    66   9e-10
UniRef50_A0LJK6 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_Q9SBM0 Cluster: Wts2L; n=3; core eudicotyledons|Rep: Wt...    66   9e-10
UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    66   9e-10
UniRef50_A2YPN0 Cluster: Putative uncharacterized protein; n=3; ...    66   9e-10
UniRef50_Q4P1P4 Cluster: Putative uncharacterized protein; n=1; ...    66   9e-10
UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; ...    66   9e-10
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    66   9e-10
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=...    66   9e-10
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici...    65   1e-09
UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena...    65   1e-09
UniRef50_Q89V28 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    65   1e-09
UniRef50_Q73Q46 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    65   1e-09
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena...    65   1e-09
UniRef50_A7IJL6 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;...    65   1e-09
UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; ...    65   1e-09
UniRef50_Q5AX52 Cluster: Putative uncharacterized protein; n=2; ...    65   1e-09
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano...    65   1e-09
UniRef50_Q04520 Cluster: Acetoin(diacetyl) reductase; n=1; Raoul...    65   1e-09
UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r...    65   2e-09
UniRef50_Q6MBQ9 Cluster: Putative uncharacterized protein; n=1; ...    65   2e-09
UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ...    65   2e-09
UniRef50_Q1NAA1 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q11K25 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09

>UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1;
           Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx
           mori (Silk moth)
          Length = 274

 Score =  178 bits (433), Expect = 1e-43
 Identities = 87/199 (43%), Positives = 128/199 (64%), Gaps = 1/199 (0%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 218
           DKV  +TG A G+G  +V+ LL E  +H+A LD+A+  G +L+A+L  K+G  + KF + 
Sbjct: 14  DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398
           DV DE         V+ +   +D VIN+AA+++     + + I++N T  + STLKA++I
Sbjct: 74  DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133

Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578
           MG   GG GG ++N+SS+ AL  +  +P+Y ATK+AVLQFS  +G  E F++T VRVL+V
Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVRVLSV 193

Query: 579 CLGATDTALLTDEKLGTFD 635
           CLG TDTA+L    L  FD
Sbjct: 194 CLGPTDTAILYKNNLTKFD 212


>UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2;
           Neoptera|Rep: Putative alcohol dehydrogenase -
           Gryllotalpa orientalis (Oriental mole cricket)
          Length = 266

 Score =  158 bits (383), Expect = 1e-37
 Identities = 81/207 (39%), Positives = 120/207 (57%), Gaps = 1/207 (0%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215
           K K   +TG ATGIG + V+ LL  GV+ +A+ D+ E  G +   +LN ++G  K  F +
Sbjct: 4   KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395
            DVT+++              G+D+VINNA +++DS   ++  I +NVTA+   T  A +
Sbjct: 64  CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121

Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
           +MGK+ GG+GG V+N++S+  L      P+Y ATK AV+  S   G P HF +TGVRVLT
Sbjct: 122 LMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVLT 181

Query: 576 VCLGATDTALLTDEKLGTFDKYLXSSC 656
           +C G TDT L+++     F   L   C
Sbjct: 182 MCPGVTDTPLISEAHHRQFTDDLGKEC 208


>UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep:
           Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 270

 Score =  153 bits (372), Expect = 3e-36
 Identities = 80/205 (39%), Positives = 125/205 (60%), Gaps = 5/205 (2%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215
           KDKV  +TGAA G+G S V IL+  G K +A++D+ +  G+ L+  LN +YG N+ +FY 
Sbjct: 4   KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395
           +DV+ EE F G+L  +V++ G ID++ NNA ++N+    ++K I +N+  ++  T  A+E
Sbjct: 63  ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKH--WEKTIAINLGGVVRGTYLALE 120

Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
            M K +GG GG ++NV+S+A L    V PIY ATK  V+ FS  +      S  GVR+  
Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180

Query: 576 VCLGATDTALL----TDEKLGTFDK 638
           +C     T+LL    ++E  G+F +
Sbjct: 181 LCPWFVKTSLLSLLNSEEHTGSFSQ 205


>UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=1; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Apis mellifera
          Length = 266

 Score =  147 bits (357), Expect = 2e-34
 Identities = 74/182 (40%), Positives = 117/182 (64%), Gaps = 1/182 (0%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215
           KDK V ITG A+G+G ++ R LL  G   IA++D AEE+G+     LN ++G N+T FY 
Sbjct: 4   KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395
            ++ +   F       V+  GG+++++NNA + N++   + K I+VNVT++I +TL  I+
Sbjct: 63  CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETD--FMKTIDVNVTSVIRATLLGIQ 120

Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
            M K  GGKGG ++N+SS+A L  +  +P+Y ATK AV+ FS    +P H+ +TGV++L 
Sbjct: 121 QMQKDLGGKGGAIVNISSLAGLYAAPQLPVYSATKHAVVSFSRSFAQPYHYKRTGVKILV 180

Query: 576 VC 581
           +C
Sbjct: 181 MC 182


>UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 329

 Score =  142 bits (344), Expect = 7e-33
 Identities = 69/195 (35%), Positives = 115/195 (58%), Gaps = 1/195 (0%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215
           KDK   + GA  G+G +  + LL  GV  + ++D+ E  G++    LN ++G N+  F +
Sbjct: 71  KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 395
            DVT    F       V   G +D+++NNAA++ D +  ++  I+ NVTA+  +++  ++
Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188

Query: 396 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
            MGK +GGKGG ++NV+SV  L     +PIY AT  AV+ FS    +P H+ +TGVR++ 
Sbjct: 189 QMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLMV 248

Query: 576 VCLGATDTALLTDEK 620
           +C G T++ +L + K
Sbjct: 249 LCPGLTESPMLENLK 263


>UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 271

 Score =  142 bits (343), Expect = 9e-33
 Identities = 73/202 (36%), Positives = 118/202 (58%), Gaps = 8/202 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKF 209
           E  +KV+ ITG   G+G    + LL+ G K +A+ D+ E  GQS   +L+ ++G  +  F
Sbjct: 2   EISNKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGF 61

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI------ 371
           Y  D+  +  F    N ++++ G IDV+INNA + N+     ++ + VNV + I      
Sbjct: 62  YPGDIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQN--IERLVNVNVVSSIDKNILR 119

Query: 372 -TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
            +  L A+  MGKH GGKGG ++NV+++  L    ++P Y ATK A++ F+ C+   E+F
Sbjct: 120 ASQILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCM--KENF 177

Query: 549 SKTGVRVLTVCLGATDTALLTD 614
           + TGVRV++VC G T T L+ +
Sbjct: 178 ATTGVRVMSVCPGVTKTNLIKE 199


>UniRef50_UPI0000513348 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=2; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Apis mellifera
          Length = 263

 Score =  141 bits (342), Expect = 1e-32
 Identities = 74/205 (36%), Positives = 118/205 (57%), Gaps = 1/205 (0%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-K 200
           M+   K+K   ITG   G+G    + LL+ G K +A+LD++   GQ     L  ++G  K
Sbjct: 1   MTDNIKNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGK 60

Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380
             FY  DV++   F  +   VV +  G+D+VINNA + ND    +++ + +NV  +I  +
Sbjct: 61  AIFYACDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGS 118

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           L A + M K  GGKGGT++N++S+ AL   +  P+Y A+K  VL FS  + R  +++ TG
Sbjct: 119 LLAFDHMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLAR--YYNNTG 176

Query: 561 VRVLTVCLGATDTALLTDEKLGTFD 635
           +R+L +C G T T+LL +    +FD
Sbjct: 177 IRILIMCPGVTTTSLLENPLSKSFD 201


>UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 261

 Score =  140 bits (338), Expect = 4e-32
 Identities = 69/191 (36%), Positives = 117/191 (61%), Gaps = 1/191 (0%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           +KV  ITG A GIG ++V+ LL+ G+K +A+ D+     + +  +L  KYGN+ + Y  D
Sbjct: 5   NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 398
           VT++  F    + V++    ID+++NNA + +D   I+ +  I++N  A++  +L  IE 
Sbjct: 65  VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121

Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578
           +GKH GGKGG ++N +S+  L     +P+Y +TK AV+ F+ C+     +  TGVRV+ +
Sbjct: 122 LGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCL--DVQYDTTGVRVVAI 179

Query: 579 CLGATDTALLT 611
           C G T+T L++
Sbjct: 180 CPGVTETPLVS 190


>UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 279

 Score =  137 bits (331), Expect = 3e-31
 Identities = 74/204 (36%), Positives = 116/204 (56%), Gaps = 2/204 (0%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE--AGQSLQAELNSKYGNKTKFY 212
           KDKV+ +TG A GIG   V   L++G +++AILDI  E      LQ E  +   ++   Y
Sbjct: 11  KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPENFTADKLQEEFGT---HRVDLY 67

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392
             D+ +EE F      V+++   +D++IN+A + N++     + ++VNV   I   L AI
Sbjct: 68  HCDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAI 125

Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
           E MGKH GG+GG V+NV+SV  L   HV+P+Y A+K A++ F+  +    +  + GV+++
Sbjct: 126 EHMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKII 183

Query: 573 TVCLGATDTALLTDEKLGTFDKYL 644
            VC G T T L  +  + T   YL
Sbjct: 184 AVCPGHTRTKLNFELAVETSVNYL 207


>UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 273

 Score =  132 bits (319), Expect = 7e-30
 Identities = 67/192 (34%), Positives = 117/192 (60%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E KDKVV ITG  +GIG S+ + +L  G K++A+ ++  E  + +  EL+ +Y ++  FY
Sbjct: 19  EVKDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFY 78

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392
             DVT  +      + V++    ID++INNA + +D+    + ++++N+ AL+ ++ K I
Sbjct: 79  PCDVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFI 136

Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
             +GKH GGKGG ++N++S+A +  S  +P+Y ATK  V+ F+  +     +  TGVRVL
Sbjct: 137 ARIGKHKGGKGGVIVNIASIAGIV-SGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVL 193

Query: 573 TVCLGATDTALL 608
            +C   T+T ++
Sbjct: 194 AICPSFTNTPIV 205


>UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 266

 Score =  132 bits (319), Expect = 7e-30
 Identities = 72/193 (37%), Positives = 112/193 (58%), Gaps = 3/193 (1%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI--AEEAGQSLQAELNSKYG-NKTKF 209
           KDKV  +TG   GIG + V+ LL  G K++AI D+        S   ++  ++G +K  F
Sbjct: 4   KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389
           Y  DVT +  F    + +V  Q  +D+++N A++ ++    +   I++N+TA++T TL  
Sbjct: 64  YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121

Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
           I+ MG+H  G+GG ++NV SV  LT S   PIY ATK  V  F+  +   +H+   GVRV
Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSL--KDHYEHLGVRV 179

Query: 570 LTVCLGATDTALL 608
           + VC G T+T+LL
Sbjct: 180 MAVCPGLTETSLL 192


>UniRef50_UPI000051334A Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) isoform 1 - Apis
           mellifera
          Length = 264

 Score =  130 bits (315), Expect = 2e-29
 Identities = 63/188 (33%), Positives = 112/188 (59%), Gaps = 1/188 (0%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 221
           K+  +TG A GIG    R LL  G K +A+LD+++  G+S  A+LN+++G ++  F   D
Sbjct: 6   KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401
           V+  E F      V+     +++++N A +M+D+   ++  +++N   ++  T+  +  M
Sbjct: 66  VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDAD--WEIMVDINYKGIVYGTILGLHTM 123

Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581
           GK+ GG GG ++N+SSVA L    + PIY  T+ A++ F+  +    ++ KTG+R+LT+C
Sbjct: 124 GKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRMLTIC 181

Query: 582 LGATDTAL 605
            G T TA+
Sbjct: 182 PGLTTTAM 189


>UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) - Tribolium castaneum
          Length = 312

 Score =  129 bits (311), Expect = 7e-29
 Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 1/202 (0%)
 Frame = +3

Query: 6   IYGTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS 185
           +Y +L  +      V  ITG A GIG ++ R+ L  G+  +A+ D ++E G+    +L  
Sbjct: 40  VYYSLGRTLSLDQNVAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLAC 99

Query: 186 KYG-NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVT 362
           ++G NK  F+  D++  + F  +    +     +++V+NNA +MND    ++  +  N++
Sbjct: 100 EFGENKVLFFDGDMSQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVN--WECQVNTNLS 157

Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542
             I  TL  ++ M K S G+GGT+INV+S+  L  S   PI+  T+  ++ FS  IG   
Sbjct: 158 GTIIGTLLGMQYMSKTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLN 217

Query: 543 HFSKTGVRVLTVCLGATDTALL 608
           HF +TGVRV  +C G T+T LL
Sbjct: 218 HFDRTGVRVTALCPGLTNTKLL 239


>UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 263

 Score =  127 bits (306), Expect = 3e-28
 Identities = 70/193 (36%), Positives = 114/193 (59%), Gaps = 3/193 (1%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS-LQAE-LNSKYGN-KTKF 209
           K+KV+ ITG   G+  +  ++LL    ++IA+ D  E+   + LQ +    ++G  +  F
Sbjct: 4   KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389
           Y SDV ++  F    + V++    +D++IN A ++ D+    +  I+VN   L+  TL A
Sbjct: 64  YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121

Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
           I+ MG H GG+GGT+INVSS+  L      P+Y ATK AV+ F+N +    H++KTGVR 
Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVRA 179

Query: 570 LTVCLGATDTALL 608
           +T+C G T T+++
Sbjct: 180 MTMCPGLTSTSMI 192


>UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 267

 Score =  126 bits (305), Expect = 4e-28
 Identities = 74/201 (36%), Positives = 119/201 (59%), Gaps = 4/201 (1%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGQSLQAELNSKYGNKT 203
           E K+KV  +TG   GIG   V+ L+   ++ +AI+D+ +   EA  +  ++LN ++G  +
Sbjct: 2   EIKNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGS 61

Query: 204 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380
            ++Y  D+T+ + F  I   V+  +  +D++IN A ++ND+       I VN TA++ S+
Sbjct: 62  YQYYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSS 119

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           + AIE M K  GGKGG V+NV+S+A +      PIY ATK AV+ F+  + +P H    G
Sbjct: 120 MIAIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL-KP-HNKIIG 177

Query: 561 VRVLTVCLGATDTALLTDEKL 623
           VRV+ +C G TDT L+  + L
Sbjct: 178 VRVVCICPGVTDTGLVAFDHL 198


>UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx
           mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk
           moth)
          Length = 289

 Score =  125 bits (301), Expect = 1e-27
 Identities = 80/209 (38%), Positives = 112/209 (53%), Gaps = 3/209 (1%)
 Frame = +3

Query: 18  LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG- 194
           LK  +E + KVV ITGAA GIG ++    L  G K I ILDI    G     ELN KYG 
Sbjct: 25  LKKENEIEGKVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGK 84

Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 374
           NK +F   D+T +     I   + ++   +DV++NNA +  +     +K +  N  A I 
Sbjct: 85  NKAEFIECDITKDLE--RISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIE 140

Query: 375 STLKAIEIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
            +LK +E M K    GKGGT+IN++S          P Y  TK A++ FS  +G   ++ 
Sbjct: 141 FSLKFMENMRKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYK 200

Query: 552 KTGVRVLTVCLGATDTAL-LTDEKLGTFD 635
           K GVRVLT+C G T+T L L + K+ + D
Sbjct: 201 KNGVRVLTICPGETNTTLGLDNTKVNSED 229


>UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep:
           CG4899-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 278

 Score =  124 bits (300), Expect = 1e-27
 Identities = 66/198 (33%), Positives = 112/198 (56%)
 Frame = +3

Query: 21  KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNK 200
           KMS   K+ VV  TG A GIG  V + LL  G   +AI+D+ +   + ++    +     
Sbjct: 17  KMSFRGKNAVV--TGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRA-AHPTQS 73

Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380
               + DV +++        + +  G ID+V+N A + ND     ++ + VN+  +I ST
Sbjct: 74  VMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINST 131

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           L A+  MGK +GGKGG V+N+SSV  L    ++P+Y ATK+ ++ F+ C+   +++ ++G
Sbjct: 132 LSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSG 191

Query: 561 VRVLTVCLGATDTALLTD 614
           ++ +TVC GAT T + T+
Sbjct: 192 IKFVTVCPGATMTDMFTN 209


>UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase
           [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin
           dehydrogenase [NAD+] - Homo sapiens (Human)
          Length = 266

 Score =  122 bits (295), Expect = 6e-27
 Identities = 66/204 (32%), Positives = 116/204 (56%), Gaps = 5/204 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 221
           KV  +TGAA GIG +    LL +G K +A++D   EAG   +A L+ ++   KT F + D
Sbjct: 6   KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401
           V D++        VV   G +D+++NNA + N+    ++K +++N+ ++I+ T   ++ M
Sbjct: 65  VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122

Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581
            K +GG+GG +IN+SS+A L      P+Y A+K  ++ F+       +   +GVR+  +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182

Query: 582 LGATDTALL----TDEKLGTFDKY 641
            G  +TA+L     +E +G + +Y
Sbjct: 183 PGFVNTAILESIEKEENMGQYIEY 206


>UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 337

 Score =  121 bits (291), Expect = 2e-26
 Identities = 64/200 (32%), Positives = 111/200 (55%), Gaps = 1/200 (0%)
 Frame = +3

Query: 18  LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG- 194
           L++S     K V ITG A G+G +     L  G   I I+DI + AG+ + A  +  +G 
Sbjct: 37  LEISGVVSGKNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGV 96

Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 374
            K  F  +DV+     +      V+    +D+V+NNA ++++    +++ I VN+  +I+
Sbjct: 97  GKVIFIHADVSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERR--WEREIAVNLNGMIS 154

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
             L +++ MG+  GG+GG ++NV+    +  +  +P+Y ATK A++  S  +  P +  +
Sbjct: 155 VALLSMQYMGRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTER 214

Query: 555 TGVRVLTVCLGATDTALLTD 614
           TGVRV+T+C G T+TAL  D
Sbjct: 215 TGVRVITLCPGLTETALTID 234


>UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4;
           Endopterygota|Rep: ENSANGP00000013280 - Anopheles
           gambiae str. PEST
          Length = 183

 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/183 (36%), Positives = 96/183 (52%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K+KV  +TGAATG+G +    LL  G K + I D+  +AG+    EL  +YG +  F   
Sbjct: 4   KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398
           DVTD   F       V     +++VINNA +MND+   ++  ++VN+   I  TL A + 
Sbjct: 63  DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNF--WELEVDVNLNGAIRGTLLAQKF 120

Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578
           M K  G  GG ++N+ S  ++T     PIY ATK A+L  +   G P H + T VR    
Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFAY 180

Query: 579 CLG 587
           C G
Sbjct: 181 CPG 183


>UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase (NAD+), partial;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to 15-hydroxyprostaglandin dehydrogenase (NAD+),
           partial - Strongylocentrotus purpuratus
          Length = 298

 Score =  120 bits (289), Expect = 3e-26
 Identities = 67/202 (33%), Positives = 113/202 (55%), Gaps = 2/202 (0%)
 Frame = +3

Query: 21  KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-N 197
           K+  + +  V  ITGAA G G++    LL   V+ I I+D     G++ + ELN KYG +
Sbjct: 37  KIKMKIQGAVALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGED 96

Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 377
           K +F++ DV+ ++      +  ++   GID+V NNA +  D +  ++K ++V++ A++  
Sbjct: 97  KVRFFQCDVSSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRG 154

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH-FSK 554
           T  A + M K+ GG+GG VIN++S+A L    + P Y A K  VL FS  +   +  F+ 
Sbjct: 155 TFLAKQYMDKNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNP 214

Query: 555 TGVRVLTVCLGATDTALLTDEK 620
             VR+  +C   ++TA+L   K
Sbjct: 215 ENVRLNCLCPSFSETAILQQMK 236


>UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to
           hydroxyprostaglandin dehydrogenase 15 (NAD); n=2;
           Tribolium castaneum|Rep: PREDICTED: similar to
           hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium
           castaneum
          Length = 479

 Score =  120 bits (289), Expect = 3e-26
 Identities = 62/199 (31%), Positives = 109/199 (54%), Gaps = 2/199 (1%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-K 200
           M  +  +KV  I+GAA+GIG ++ + LL  G++ + I D+ +E G+    E+ +++G+ +
Sbjct: 1   MPFDINNKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGR 60

Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380
             F  +DV+  + F       +     ID+++N A ++NDSI  +++ I +NV   +   
Sbjct: 61  AIFVLTDVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSI--WQQEIAINVNGTVHGI 118

Query: 381 LKAIE-IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           L A+E  + K+     G ++N SS+A +      PIY  TK A+   +   G   H+ +T
Sbjct: 119 LLALENYIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERT 178

Query: 558 GVRVLTVCLGATDTALLTD 614
            VR++ +C G TDT LL D
Sbjct: 179 KVRIMAICPGPTDTPLLRD 197



 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%)
 Frame = +3

Query: 90  VVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSDVTDEEHFLGILNAVV 266
           +VR     G   + I DI  E G+ +  E+ +++G NK  +  +DVT +  +       +
Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292

Query: 267 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 443
           +    +D+V+N A ++N+    +++ +++N+   +  T+ A+E  + K+  G  G ++N+
Sbjct: 293 ETFQNLDIVVNGAGIVNELD--WQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350

Query: 444 SSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCLGATDT 599
           SS A L      PIY  TK AV+  S   G   H+ +T VRVLT C G T+T
Sbjct: 351 SSAAILDCFPPYPIYTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTET 402


>UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG4899-PA, isoform A - Tribolium castaneum
          Length = 295

 Score =  114 bits (275), Expect = 2e-24
 Identities = 64/191 (33%), Positives = 97/191 (50%), Gaps = 1/191 (0%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 221
           KV  ITG + GIG +V   +L E  K++A++ +    G+     LNS YG NK  F+  D
Sbjct: 52  KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401
           V  +       N V++E G ID+VIN A + +     ++K I  N+   I  TL+A  +M
Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRC--WEKEIMTNLVGTIHCTLEAYRVM 169

Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581
            K   G GG ++N S +  +      P   A+   ++  S   G   +F  TGVRV+T+C
Sbjct: 170 SKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVVTLC 229

Query: 582 LGATDTALLTD 614
            G T+T  + D
Sbjct: 230 PGITNTNFIKD 240


>UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 268

 Score =  107 bits (256), Expect = 3e-22
 Identities = 62/192 (32%), Positives = 104/192 (54%), Gaps = 4/192 (2%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGQSLQA--ELNSKYG-NKTKF 209
           +KV  +TG   GIG  +V+  L  G K +AI D+  EE  + + A  +L  ++   +  +
Sbjct: 5   NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALKQLEQEFAAQRFSY 64

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389
           Y  DVT+ + F+   + V    G +D+++NNA +  +        + VN T++I  T+ A
Sbjct: 65  YCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMHA 122

Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
           IE MG + GGKGG ++ + S+ AL     +P+Y ATK A+  F       ++ +K GVR+
Sbjct: 123 IERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVR--STKDYNAKYGVRI 180

Query: 570 LTVCLGATDTAL 605
           + +C G T T +
Sbjct: 181 VCLCPGMTKTKM 192


>UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep:
           CG18814-PA - Drosophila melanogaster (Fruit fly)
          Length = 285

 Score =  106 bits (254), Expect = 5e-22
 Identities = 70/217 (32%), Positives = 114/217 (52%), Gaps = 18/217 (8%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS-D 221
           K V   G   GIG+  V+ LL + +K +AI D+  +    L AE   ++ +   FY+  D
Sbjct: 6   KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 362
           +T +        A  ++ G  DVV+N + L++D     +I I    +E+ ++        
Sbjct: 64  ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123

Query: 363 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533
               +I STL A+E M K  GG+GG ++N+SSVA L  + +M IY  +K+ V  F+  + 
Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 183

Query: 534 RPEHFSKTGVRVLTVCLGATDTALLTD-EKLGTFDKY 641
            P H++ +GV  +T+C G T+T +L D +K  TF  Y
Sbjct: 184 SPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFY 220


>UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium
           castaneum|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Tribolium
           castaneum
          Length = 255

 Score =  103 bits (246), Expect = 5e-21
 Identities = 60/192 (31%), Positives = 103/192 (53%), Gaps = 1/192 (0%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E K KV  +TG A+GIG ++VR LL  G+K ++++DI+E        EL     ++  F 
Sbjct: 3   ELKGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISENT------ELQD---SRVTFI 53

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392
           ++DVT ++      +  V     +D+V+NNA ++ D I  +K+ I++N+ A+I  T  A+
Sbjct: 54  KTDVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLAL 111

Query: 393 EI-MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
              + K+     G ++N +SV  L      PIY  +K  V+     +G P  + +  VR+
Sbjct: 112 RTYLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRI 171

Query: 570 LTVCLGATDTAL 605
           +T+C G  DT +
Sbjct: 172 VTICPGLVDTPM 183


>UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4;
           Proteobacteria|Rep: Putative dehydrogenase - Azoarcus
           sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 267

 Score =  101 bits (241), Expect = 2e-20
 Identities = 68/211 (32%), Positives = 107/211 (50%), Gaps = 10/211 (4%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M      KV +++GAA+GIG ++ R+   EG   + + D+  E G+++ A +  + G + 
Sbjct: 1   MKQNLSGKVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRA 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 365
            F   DV+DE  +   L   V+E GG+D+++NNA       L +  +    K + VNV  
Sbjct: 59  LFIHHDVSDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAG 118

Query: 366 LITSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542
           +I     AI  M    S GKGG++IN+SSVA L  +  + +Y ATK AV   S       
Sbjct: 119 VILGHKHAIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVEC 178

Query: 543 HFSKTGVRVLTVCLGATDTAL---LTDEKLG 626
                G+RV ++  G  DT +   L D+ +G
Sbjct: 179 GRLGYGIRVNSIHPGLVDTDMGVKLVDDFVG 209


>UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma
           infestans|Rep: Oxidoreductase - Triatoma infestans
           (Assassin bug)
          Length = 252

 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 67/196 (34%), Positives = 105/196 (53%), Gaps = 8/196 (4%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           WKD+V  +TGA+ GIGE++ R L + G+K +A L    +  Q LQ + N+  G+  K Y+
Sbjct: 4   WKDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYK 61

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITS 377
            DVT+E      + ++V + G I V++NNA L     M D S G  ++  E NV  L+T 
Sbjct: 62  CDVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTF 121

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVA--ALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
           T   +EIM KH+    G +IN++S+A   +     M  Y A+K AV   +  +       
Sbjct: 122 TQHVVEIMKKHN-ITDGHIININSLAGHVIIPKPGMANYTASKHAVTVLTESLKNELAAM 180

Query: 552 KTGVRVLTVCLGATDT 599
           K+ +RV ++  G  +T
Sbjct: 181 KSKIRVTSISPGLVNT 196


>UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1;
           Planctomyces maris DSM 8797|Rep: Probable putative
           oxidoreductase - Planctomyces maris DSM 8797
          Length = 270

 Score = 96.3 bits (229), Expect = 6e-19
 Identities = 62/196 (31%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           ++D+VV +TG + GIGE   R+   EG  H+AIL     AGQ L  ELN     K  F +
Sbjct: 18  FQDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQ 76

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLK 386
            DV + E     ++ VV++ G +D +INNA +   ++ + + +IE     +     ST  
Sbjct: 77  CDVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFA 136

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
             +    H     GT+IN+SS+ A+   H    Y +TK A + F+  +       + GVR
Sbjct: 137 GAKYALPHLRKTKGTIINMSSMTAVLGQHHSTAYCSTKGAQVSFTKSLA--IELGEAGVR 194

Query: 567 VLTVCLGATDTALLTD 614
           V  +     DT L+ D
Sbjct: 195 VNAILPSNIDTPLMRD 210


>UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=10; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium sp. (strain
           JLS)
          Length = 282

 Score = 95.9 bits (228), Expect = 8e-19
 Identities = 58/206 (28%), Positives = 104/206 (50%), Gaps = 8/206 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E + +V  +TG A+GIG  V    + EG K + I D+ +E G++L  +     G    F+
Sbjct: 8   ELQGRVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFH 62

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTAL 368
            +DV D+E    +++  V+  G +DV++NNA         L N+ +  + + + VN+ ++
Sbjct: 63  HTDVGDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSV 122

Query: 369 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
           +  T  A   M +H GG   ++IN+SS+  +     +P+Y A+K+A+L F+ C       
Sbjct: 123 MAGTRDAGRYMSEHGGG---SIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAA--IEL 177

Query: 549 SKTGVRVLTVCLGATDTALLTDEKLG 626
           +   +RV  +  G   T +L     G
Sbjct: 178 AHYDIRVNCIAPGNIPTPILQSSATG 203


>UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23;
           Schizophora|Rep: Alcohol dehydrogenase - Bactrocera
           oleae (Olive fruit fly)
          Length = 258

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 2/188 (1%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--QSLQAELNSKYGNKTKFYRSD 221
           VVF+ G    IG    + ++ + V    + D+ E A   ++LQA +N K   K  + + D
Sbjct: 8   VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401
           +T++         V+ +   IDV++N A ++ D     +  + +N+  LI +TL+AI +M
Sbjct: 64  ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121

Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581
            K+  G+GG ++N++SV  L  +    IY A+K  V+ FS  I  P +++ TG+ V T C
Sbjct: 122 DKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVATFC 181

Query: 582 LGATDTAL 605
            G T+T L
Sbjct: 182 PGLTETPL 189


>UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=7; Alphaproteobacteria|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 261

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 58/169 (34%), Positives = 91/169 (53%), Gaps = 7/169 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF-YRSD 221
           K  FITG A G+G +  R+L  EG K +A+ DI     Q++  E+N+ +G  T F +  D
Sbjct: 11  KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 383
           VT E+ ++ +L       GG+ V++NNA +  D        G++KK + VNV ++     
Sbjct: 70  VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530
            A+  M  H   + G++IN+SS+A L  +   P Y A+K+AV   S  I
Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGLIANGNSPAYNASKAAVWLLSKNI 175


>UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 266

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 61/194 (31%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSDV 224
           V  +TG   GIG ++ + LLD   K + +LDI E+ G      L+  Y  ++  F + DV
Sbjct: 7   VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 389
           T +              G +D++ NNA +    ND +  G +K  I++NV  +I  TL  
Sbjct: 66  TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125

Query: 390 IEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           ++ MG     G GGT++NV+S+A L  +   P+Y A+K AV+  +  +     ++   VR
Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTL--TSLWATECVR 183

Query: 567 VLTVCLGATDTALL 608
           V  +C   TDTA++
Sbjct: 184 VNCICPSFTDTAMV 197


>UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima
           TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to
           tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 291

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 8/195 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TG A G+G S+   L   G+K IAILD+ ++ G     +L+  YG + +FY++DV
Sbjct: 46  KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 386
            DEE    I++ VV + G +DVV+N+A + +           +++ I++N+      T  
Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCIGRPEHFSKTG 560
           A   M K   G GGTV+ ++S++    +   P   Y A+K+AV   S  +     ++   
Sbjct: 166 AARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAAVKHLSKSLA--AEWAVHN 221

Query: 561 VRVLTVCLGATDTAL 605
           +R  ++  G  DTAL
Sbjct: 222 IRCNSISPGYMDTAL 236


>UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family
           protein; n=4; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase family protein - Gramella
           forsetii (strain KT0803)
          Length = 249

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 9/204 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K K + ITGA++GIGE+    L  EGV ++ +    EE  + L+++++ + G K      
Sbjct: 4   KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 380
           DVT +E F  +++   +E G ID +INNA LM      N     + K ++VN+  ++   
Sbjct: 63  DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
              +  M +    K G +IN+SS AA        +Y ATKSAV  FS  + R E   K  
Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGL-RQELAPKFN 178

Query: 561 VRVLTVCLGATDTAL---LTDEKL 623
           + + ++  G  DT L   +TD+++
Sbjct: 179 INITSIEPGFVDTELTDTITDDEI 202


>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
           Oxidoreductase - Oceanobacillus iheyensis
          Length = 244

 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 6/198 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           +DKV  ITG  +GIG +  ++   EG K I ++D+ EE G S++AEL S+ G++  F ++
Sbjct: 4   QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 380
           DVT+EE    I    +   G +D++ NNA +         +   ++K +EV++  +    
Sbjct: 62  DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
             AI+   K      G ++N +S+     S     Y A K+ V+  +  +G    ++   
Sbjct: 122 QAAIKEFLK---AGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGL--EYAARN 176

Query: 561 VRVLTVCLGATDTALLTD 614
           +RV  +C G  DTA+L D
Sbjct: 177 IRVNALCPGFIDTAILGD 194


>UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae
           str. PEST
          Length = 191

 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 58/195 (29%), Positives = 99/195 (50%), Gaps = 1/195 (0%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS   +  VVF  G   G+G ++ + LL +GVK + I+D+ E    +L     S      
Sbjct: 1   MSLAGQSAVVF--GGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALI 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 380
                D+++      +L   + E  G ID+++N+A ++   +    K I    T +I S 
Sbjct: 59  LCKICDISNRAALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSC 113

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           L A+ +M +  GGKGG ++NV+S A L     +P Y A+K  ++ F+  +G    +S+TG
Sbjct: 114 LIALNLMSRAKGGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETG 173

Query: 561 VRVLTVCLGATDTAL 605
           V+ + +C G T T +
Sbjct: 174 VKFIIICPGGTRTRM 188


>UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus
           furiosus
          Length = 260

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 60/201 (29%), Positives = 103/201 (51%), Gaps = 6/201 (2%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K+KV  +TG   GIG ++ ++  + G K + + +I EEAG   +A L  + G    F ++
Sbjct: 7   KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 380
           DV DEE    ++   V+  GG+D+++NNAA+M+       ++  +++ I VN+T     +
Sbjct: 65  DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
             A E M K     GG +IN++S  AL        Y A+K  +L  ++ +      +K  
Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLA--ISLAKYR 179

Query: 561 VRVLTVCLGATDTALLTDEKL 623
           +RV+ V  G  +T+     KL
Sbjct: 180 IRVVAVSPGWIETSRWKKSKL 200


>UniRef50_Q2W431 Cluster: Dehydrogenase with different
           specificities; n=2; Magnetospirillum|Rep: Dehydrogenase
           with different specificities - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 248

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 63/201 (31%), Positives = 100/201 (49%), Gaps = 6/201 (2%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           +++DKV  ITG A+GIG   V+ + + G   + I DI  EAG+   AEL +K G K +F 
Sbjct: 2   KFEDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFV 59

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 374
           R DVTD+ +   +   VV  +G +D++ N A        +++      K + +N+T  I 
Sbjct: 60  RLDVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIE 119

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
                  +M +   GK   ++NV+S A    S    +Y A K  ++ FS  + R    ++
Sbjct: 120 LIRAFFPLMIEKKTGK---IVNVASDAGRVGSLGESVYSAAKGGLIAFSKALAR--EGAR 174

Query: 555 TGVRVLTVCLGATDTALLTDE 617
             + V  +C G TDT LL  E
Sbjct: 175 FNINVNAICPGPTDTPLLKSE 195


>UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=2; Actinomycetales|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Mycobacterium avium (strain 104)
          Length = 250

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 57/189 (30%), Positives = 102/189 (53%), Gaps = 4/189 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGAA+GIGE+  + L ++G K + + DI E+ G+ + AE+ ++ G +  F R+D+
Sbjct: 6   KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 395
           + EE    +++  V   GG+ +  NNAA+ +    +++ + +V   VT + +  T   + 
Sbjct: 64  SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123

Query: 396 IMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
               H  G  GG ++N +S AAL  +  M  Y ATK  ++  +   G    +++ G+RV 
Sbjct: 124 AEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGL--DYARNGIRVN 181

Query: 573 TVCLGATDT 599
            V  G+  T
Sbjct: 182 AVAPGSIKT 190


>UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:
           Dehydrogenase - Bradyrhizobium japonicum
          Length = 271

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 59/203 (29%), Positives = 106/203 (52%), Gaps = 7/203 (3%)
 Frame = +3

Query: 18  LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197
           + M+ + + KV  +TG A+GIGE++V +   EG   IA  D+ E  G  L A+  +K G 
Sbjct: 1   MNMAGQVEGKVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPEL-AKRITKAGG 58

Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVN 356
           K  F   DV+ EE ++ I+  + +  G +D++++NA       ++++ ++G ++K   +N
Sbjct: 59  KAIFLEQDVSSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAIN 118

Query: 357 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536
           +  +  S    + +M K     GG+++ +SS+A L  +  +  Y ATK  V  F+  I  
Sbjct: 119 LDGVFLSVKHCLPLMRKTG---GGSIVMMSSLAGLRGAPGLSAYSATKGGVRLFAKSIAM 175

Query: 537 PEHFSKTGVRVLTVCLGATDTAL 605
                  G+RV +V  G  DT +
Sbjct: 176 ECAAVGDGIRVNSVHPGIIDTPI 198


>UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 249

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 56/200 (28%), Positives = 103/200 (51%), Gaps = 6/200 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           ++KV+ +TG + GIG+++     DEG K +   +  EE+ +++  E++ K G+     ++
Sbjct: 6   ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 380
           DV +E+    ++N +  E G +D+++NNA +M +++ +  K  E       N       +
Sbjct: 65  DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
             A ++M KH   K G +IN+SSV  +  S    +Y ATKS ++ F+  + +       G
Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAK--ELGPFG 179

Query: 561 VRVLTVCLGATDTALLTDEK 620
           + V  +  G  DT L  D K
Sbjct: 180 ITVNAIAPGFIDTDLTHDVK 199


>UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain
           dehydrogenase/reductase SDR - Flavobacterium johnsoniae
           UW101
          Length = 269

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 61/190 (32%), Positives = 101/190 (53%), Gaps = 6/190 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYR 215
           KDK + ITG  TGIG+++  +L+  G + + I    E+  ++  A++  ++ G++     
Sbjct: 30  KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 380
           +DVT +E    IL     E GGID++INNAAL      N+S   YK  I+ N+T  +   
Sbjct: 89  ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
            +A   M +    K G +IN+ S++A ++     IY ATKSA+  FS  + +    +  G
Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSAESKEAKSTIYVATKSAIRGFSTSLRK--ELNPLG 203

Query: 561 VRVLTVCLGA 590
           ++V  +  GA
Sbjct: 204 IKVSLIEPGA 213


>UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=16; Bacillaceae|Rep:
           Oxidoreductase, short-chain dehydrogenase/reductase
           family - Bacillus anthracis
          Length = 264

 Score = 87.4 bits (207), Expect = 3e-16
 Identities = 65/212 (30%), Positives = 107/212 (50%), Gaps = 7/212 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M+   ++KV+ ITGA++GIGE V   + ++G   + ++   EE  ++L  ++   Y    
Sbjct: 1   MTGRLQNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPC 59

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365
            +Y  DV++E     + + V+QE G ID+++NNA         + S+   K   +VNV  
Sbjct: 60  YYYVLDVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFG 119

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           L+  T   +  M K + G    +IN++S+A    +     Y ATK AVL F+N + R E 
Sbjct: 120 LVACTKAVLPYMVKRNEGH---IINIASLAGKIATPKSSAYAATKHAVLGFTNSL-RME- 174

Query: 546 FSKTGVRVLTVCLGATDTALL-TDEKLGTFDK 638
            S T V V  +  G  DT      ++ GT+ K
Sbjct: 175 LSSTNVFVTAINPGPIDTNFFEIADQSGTYVK 206


>UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 251

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 63/203 (31%), Positives = 99/203 (48%), Gaps = 6/203 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITG A G GE+  R  + EG + + I D+ +EAGQ + AEL    G+  +F   DV
Sbjct: 7   KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 386
           T E  +   ++A + + G +D+++NNAA++        S+  Y+K I+VN          
Sbjct: 62  TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A   +G      GG+++NVSS A +        Y ++K AV   +        F + G+R
Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAAL--EFGRYGIR 176

Query: 567 VLTVCLGATDTALLTDEKLGTFD 635
           V +V  G  DT +    +   FD
Sbjct: 177 VNSVHPGGIDTVMARPPEFADFD 199


>UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase
           bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis
           oxidoreductase bacC - Bacillus subtilis
          Length = 253

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 61/194 (31%), Positives = 101/194 (52%), Gaps = 6/194 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           DK V ITG A+GIG + V+  L +   ++ + DI E  G+++  + N+   ++  F ++D
Sbjct: 5   DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 383
           +TDE      + + V   GG+DV+INNA       +    +  + K ++VN+T +   + 
Sbjct: 61  ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            A++ M   + GK G +IN  SV  L     +P Y A+K  VLQ +  +     ++K  +
Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA--VDYAKHQI 175

Query: 564 RVLTVCLGATDTAL 605
           RV  VC G  DT L
Sbjct: 176 RVNCVCPGIIDTPL 189


>UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus
           sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp.
           B14905
          Length = 252

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 7/198 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E  +K+  +TGA +GIG +    L   G K + I+D  +E G+    +L  + G +  F 
Sbjct: 2   EHLNKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFV 59

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 371
           ++DV+  E     +NA V+  G IDV  NNA ++     +       Y + + +NV  + 
Sbjct: 60  QADVSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVF 119

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
                 I++M    G   G++IN +S A +   H M +Y A+K AV+  +        + 
Sbjct: 120 LGLKHVIKVM---EGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASL--EYV 174

Query: 552 KTGVRVLTVCLGATDTAL 605
           K G+R+  +C G  +TAL
Sbjct: 175 KKGIRINAICPGGVETAL 192


>UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Herpetosiphon aurantiacus ATCC
           23779|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Herpetosiphon aurantiacus ATCC 23779
          Length = 247

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 57/195 (29%), Positives = 102/195 (52%), Gaps = 7/195 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TG A GIG +  ++L  +G   + I DI E+ G +   ++    G +  F   DV
Sbjct: 5   KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 383
           + E     ++   + +QGG+D++INNA +      ++       ++ +++++T +     
Sbjct: 63  SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            A + M   +GGKGG ++NV+S+A +  S  +  Y   K+ V+Q S   G  E  +  G+
Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSK-TGAIE-LASAGI 177

Query: 564 RVLTVCLGATDTALL 608
           R+  VC G T+TA+L
Sbjct: 178 RINAVCPGWTETAIL 192


>UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1;
           Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP]
           reductase - Psychroflexus torquis ATCC 700755
          Length = 251

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 64/193 (33%), Positives = 103/193 (53%), Gaps = 2/193 (1%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M  + K K   ITG + GIG+S+   L +EGV +IAI    +EA Q  + EL  K G K 
Sbjct: 1   MDLQLKGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKV 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITS 377
                DV D E F   L AV  E G +D+++NNA+   M D    ++ ++++++ A + +
Sbjct: 59  FTQTCDVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRA 118

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           T K +  M + SG   G ++ +SSV+ L +S   P Y A K+A++ +S  +      +  
Sbjct: 119 TKKVVPWMSE-SG--SGNILFISSVSGL-ESGSPPAYAAAKAALISYSKTMA--VQLAPQ 172

Query: 558 GVRVLTVCLGATD 596
            +RV T+  GA +
Sbjct: 173 HIRVNTIAPGAIE 185


>UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Sphingomonadales|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingopyxis alaskensis
           (Sphingomonas alaskensis)
          Length = 285

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 4/189 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGAA+GIG++ V  L  EG  H+   DI E  G++L    N +      F R DV
Sbjct: 6   KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 395
           T       +++A   + GGID+V NNAA   D   I +   +  +  +  ++ S    I 
Sbjct: 61  TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120

Query: 396 IMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
               H  G KG +++N +SVAAL   +    Y   K+ VL  +         ++ G+RV 
Sbjct: 121 YAAPHMKGRKGASIVNTASVAALGAGYSPTAYAVAKAGVLHLTRVAA--TDLAQYGIRVN 178

Query: 573 TVCLGATDT 599
            +C G  +T
Sbjct: 179 AICPGFINT 187


>UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1;
           Apis mellifera|Rep: Short-chain dehydrogenase/reductase
           - Apis mellifera (Honeybee)
          Length = 246

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 53/201 (26%), Positives = 104/201 (51%), Gaps = 9/201 (4%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M   W D+V  +TGA +GIG+ ++  L+ +G+K I I    ++  ++L  EL SK G K 
Sbjct: 1   MEQNWIDEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KL 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365
              + D++++   L ++  V +  G ID++INNA       L ND +  +KK  ++N+  
Sbjct: 59  VPLQCDLSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLG 118

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALT---QSHVMPIYFATKSAVLQFSNCIGR 536
           L     + +++M K  G   G ++N++  + L     +   P Y A+K A+   ++C+  
Sbjct: 119 LTCMIQEVLKLM-KKKGINNGIIVNINDASGLNLLPMNRNRPAYLASKCALTTLTDCLRS 177

Query: 537 PEHFSKTGVRVLTVCLGATDT 599
                ++ ++V+++     +T
Sbjct: 178 ELAQCESNIKVISISPDLVET 198


>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 277

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 57/193 (29%), Positives = 101/193 (52%), Gaps = 6/193 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K+  +TGAA G+G ++ +  L+EG   + + D++EE      AEL +    +    R DV
Sbjct: 9   KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386
            D E F  +++A V E G +D+++NNA +         S+  +   + VNV+++      
Sbjct: 64  GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           AI  M +  GG    +INV+S+A L    +   Y A+K+AV+ F+  +   +H +   +R
Sbjct: 124 AIPHMRRQGGG---AIINVASIAGLRGETLAAAYSASKAAVVNFTRSLAL-DH-ADENIR 178

Query: 567 VLTVCLGATDTAL 605
           V  +C G+ +T +
Sbjct: 179 VNAICPGSVETEM 191


>UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member
           11 precursor; n=30; Euteleostomi|Rep:
           Dehydrogenase/reductase SDR family member 11 precursor -
           Homo sapiens (Human)
          Length = 260

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 11/199 (5%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--QSLQAELNSK-YGNKTK 206
           W+D++  +TGA+ GIG +V R L+ +G+K   ++  A   G  + L AE  S  Y     
Sbjct: 9   WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65

Query: 207 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 368
            YR D+++EE  L + +A+  +  G+D+ INNA       L++ S   +K    VNV AL
Sbjct: 66  PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125

Query: 369 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPE 542
              T +A + M K      G +IN++S++   +    V   Y ATK AV   +  + +  
Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184

Query: 543 HFSKTGVRVLTVCLGATDT 599
             ++T +R   +  G  +T
Sbjct: 185 REAQTHIRATCISPGVVET 203


>UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep:
           Blr4846 protein - Bradyrhizobium japonicum
          Length = 255

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 55/170 (32%), Positives = 87/170 (51%), Gaps = 5/170 (2%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           D+VV ITG A+GIG + VR    +G + +A LDI E AG SL  E+ +  G    F R D
Sbjct: 11  DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI--- 392
           + D +     +  V    G   V++NNAA  ND   +  +        +I   LK +   
Sbjct: 70  LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127

Query: 393 --EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536
              ++ +     GG++IN+SS+A +     +P+Y A K+A++ F+N + R
Sbjct: 128 AQAVVPQMQARGGGSIINMSSIAWMRGGPALPVYAAAKAAIVGFTNSLAR 177


>UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
          Length = 260

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 7/206 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           +K + ITG A+GIG +  ++L   G K I I D+AE+ G +L  +  +   +   F + D
Sbjct: 14  NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 380
           VT       +    V++ GG+DVVINNA + +    +++       + + VNV  +    
Sbjct: 72  VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
             AI  +  H GG    VINV+S+A L  + ++  Y A+K AV+  +        +++  
Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPMLSAYSASKHAVIGLTK--SAAIEYARAN 186

Query: 561 VRVLTVCLGATDTALLTDEKLGTFDK 638
           +R   VC    DT ++ +  L   +K
Sbjct: 187 IRFNAVCPSFIDTPMVRNSMLNMNEK 212


>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Leptospira interrogans
          Length = 254

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 58/203 (28%), Positives = 99/203 (48%), Gaps = 6/203 (2%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K K   +TGAA GIG+S    L   G  ++ I D+ EE+ ++   E++ + G K     +
Sbjct: 5   KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 380
           +V+D +     + A V E G +D+++NNA +  D++ +  K       I VN+T     T
Sbjct: 64  NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
             AI+ M K+    GG++IN+SS+A +  +     Y A+K+ V+ F+  +       K  
Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVR 181

Query: 561 VRVLTVCLGATDTALLTDEKLGT 629
              +     AT+      EK+ T
Sbjct: 182 CNAIAPGFIATEMTDAIPEKIRT 204


>UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa
           protein; n=44; Drosophiliti|Rep: Alcohol
           dehydrogenase-related 31 kDa protein - Drosophila
           melanogaster (Fruit fly)
          Length = 272

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 55/190 (28%), Positives = 93/190 (48%), Gaps = 1/190 (0%)
 Frame = +3

Query: 75  GIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT-DEEHFLGI 251
           GI     ++L+ + +  +AIL   E   Q++    + K   +  F+  DVT   E     
Sbjct: 17  GIALETSKVLMTKNIAKLAILQSTENP-QAIAQLQSIKPSTQIFFWTYDVTMAREDMKKY 75

Query: 252 LNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGT 431
            + V+ +   IDV+IN A L +++       I  N+T ++ +    +  M +  GG GG 
Sbjct: 76  FDEVMVQMDYIDVLINGATLCDENN--IDATINTNLTGMMNTVATVLPYMDRKMGGTGGL 133

Query: 432 VINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCLGATDTALLT 611
           ++NV+SV  L  S V   Y A+K  V+ F+  +  P ++S+ GV V+ VC G   T +  
Sbjct: 134 IVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCG--PTRVFV 191

Query: 612 DEKLGTFDKY 641
           D +L  F +Y
Sbjct: 192 DRELKAFLEY 201


>UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces
           avermitilis|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 258

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 59/199 (29%), Positives = 104/199 (52%), Gaps = 6/199 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +VV I+GAA G GE   R+ ++EG K + + D+ ++ G++L  E+ ++Y         DV
Sbjct: 7   RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 386
             E+ +   +       G ID ++NNA ++  ND +G     +++ ++VN   +    +K
Sbjct: 60  GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
            +    + +G  GGT++N +S A LT    +  Y ATK A++  +  +   E  +K  +R
Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTR-VAALELAAKK-IR 174

Query: 567 VLTVCLGATDTALLTDEKL 623
           V  VC GA DTA+    +L
Sbjct: 175 VNAVCPGAIDTAMSNPSQL 193


>UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 258

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 55/190 (28%), Positives = 97/190 (51%), Gaps = 3/190 (1%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TG A G+G +  R+ + EG   + I D+ +  G++L  EL    G+  +F R DV
Sbjct: 7   KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 398
            DE +++ + +A +++ G IDV++NNAA++       + K+  E  V+  +  T   I  
Sbjct: 62  ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121

Query: 399 MGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
           +  H    K G+++N+SSV  L   + +  Y ++K  V   +            GVRV +
Sbjct: 122 IAPHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAAL--ELGHQGVRVNS 179

Query: 576 VCLGATDTAL 605
           +  G  +TA+
Sbjct: 180 IHPGGVNTAM 189


>UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Parvibaculum
           lavamentivorans DS-1
          Length = 268

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 57/197 (28%), Positives = 95/197 (48%), Gaps = 9/197 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGAA GIG +  + L  EG K +   D   E GQ +  E+  + G  T F+R DV
Sbjct: 7   KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 383
           TDE  +  ++    ++ GG+ VV+NNA +  +       ++  ++  IEV++ ++     
Sbjct: 65  TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124

Query: 384 KAIEIMGKHS--GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
             I  + K++  GG GG ++N+SS+  L        Y A K  V   +         +  
Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECADAGY 184

Query: 558 GVRVLTVCLGATDTALL 608
            +RV +V  G  DT ++
Sbjct: 185 NIRVNSVHPGYIDTPMV 201


>UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep:
           Fat body protein 2 - Drosophila melanogaster (Fruit fly)
          Length = 256

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 55/194 (28%), Positives = 98/194 (50%), Gaps = 2/194 (1%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGQSLQAELNSKYGNKTK 206
           +W  K V   G+ +GIG  ++  L+ + +K + I+   E  E  + LQA +N     K  
Sbjct: 3   DWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMMKKLQA-INPSV--KVV 59

Query: 207 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 386
           F + ++ ++      +  + Q  G IDV+IN   ++ D     +  + +N+T +I ST+ 
Sbjct: 60  FMQMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKD--VETTMGMNLTGMIQSTMM 117

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A+  M K   G GG V+N+SSV  L  +    +Y A    +L F+  +G    + KTGV 
Sbjct: 118 AMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVM 177

Query: 567 VLTVCLGATDTALL 608
            + +C G T++ ++
Sbjct: 178 FMAMCPGLTNSEMI 191


>UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485;
           Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila
           melanogaster (Fruit fly)
          Length = 256

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 57/189 (30%), Positives = 92/189 (48%), Gaps = 2/189 (1%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAE-LNSKYGNKTKFYRSDV 224
           V+F+ G   GIG    + LL   +K++ ILD  E      + + +N K      FY  DV
Sbjct: 10  VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66

Query: 225 TDE-EHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 401
           T        +L  +  +   +DV+IN A +++D     ++ I VN T L+ +T   ++  
Sbjct: 67  TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQ--IERTIAVNYTGLVNTTTAILDFW 124

Query: 402 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 581
            K  GG GG + N+ SV      + +P+Y  TK+AV+ F++ + +      TGV   TV 
Sbjct: 125 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVN 182

Query: 582 LGATDTALL 608
            G T T L+
Sbjct: 183 PGITRTTLV 191


>UniRef50_Q28GY1 Cluster: Novel protein containing short chain
           dehydrogenase domain; n=4; Deuterostomia|Rep: Novel
           protein containing short chain dehydrogenase domain -
           Xenopus tropicalis (Western clawed frog) (Silurana
           tropicalis)
          Length = 255

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF-Y 212
           WK +V  +TGA+ GIG +V R+L+  G+K +      ++  + L AE  S     T F Y
Sbjct: 4   WKGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKI-EKLAAECQSAGYPGTLFPY 62

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 374
           + D+++EE  L + +A+     G+DV INNA       L++     ++  I+VNV AL  
Sbjct: 63  KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSI 122

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYF--ATKSAVLQFSNCIGRPEHF 548
            T +A + M K      G +IN++SV           +F  ATK  V   +  I +    
Sbjct: 123 CTREAYQSM-KERNIDDGHIININSVLGHIYQCAKQAHFYCATKHTVTALTEAIRQELRE 181

Query: 549 SKTGVRVLTVCLGATDT 599
            K+ +RV ++  G  +T
Sbjct: 182 LKSHIRVTSISPGLVET 198


>UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Leptospira interrogans
          Length = 256

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 60/204 (29%), Positives = 102/204 (50%), Gaps = 7/204 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M +  KDKV  +TG +TGIG++VV+  + +GVK +       E G+ L++E+ ++ G   
Sbjct: 1   MENIMKDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDV 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVT 362
            F   DVT  E    +++A +++ G +D  INNA +M  N  +      ++ K + VN+ 
Sbjct: 59  YFVVCDVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLK 118

Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542
               S    I  M K     GG V+NVSS++ +     +  Y A K  V+  +       
Sbjct: 119 GTWLSMKYQIPEMIKMG---GGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAAL-- 173

Query: 543 HFSKTGVRVLTVCLGATDTALLTD 614
            ++K  +R+  +C GA  T +L +
Sbjct: 174 EYAKKNIRINAICPGAVKTEILDE 197


>UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4;
           Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase
           - Comamonas testosteroni (Pseudomonas testosteroni)
          Length = 254

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 53/168 (31%), Positives = 93/168 (55%), Gaps = 6/168 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M++  + KV  +TG A+G+G  VV++LL EG K +A  DI E AGQ L AEL    G ++
Sbjct: 1   MTNRLQGKVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERS 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365
            F R DV+ E  +  ++ AV +  G ++V++NNA ++         +  + + +++N  +
Sbjct: 56  MFVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTES 115

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 509
           +     + I  M +     GG++IN++SV++         Y A+K+AV
Sbjct: 116 VFIGCQQGIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAV 159


>UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4;
           Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella
           melitensis
          Length = 272

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 59/197 (29%), Positives = 95/197 (48%), Gaps = 6/197 (3%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           +KDKVV +TG A+GIGE+  R  + EG K + I D ++  GQ L  EL   +  +  F +
Sbjct: 3   FKDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIK 59

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 377
           +DV D      ++   V+  G +D++  NA +  D+         ++K I++N+T +   
Sbjct: 60  TDVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLC 119

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
              AI+ M   S G GG ++N  S+ +      +  Y A K  V   +  +     +   
Sbjct: 120 DKYAIDQM--RSQG-GGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLA--IDYGPQ 174

Query: 558 GVRVLTVCLGATDTALL 608
            +RV  VC G  DT LL
Sbjct: 175 NIRVNAVCPGYIDTPLL 191


>UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Oceanobacillus iheyensis
          Length = 253

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 52/201 (25%), Positives = 102/201 (50%), Gaps = 7/201 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           KDKV  +TGAA+G+G+++  +   EG K + + D+ EE  QS+  E+ S  G  T   + 
Sbjct: 4   KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 377
           ++  +E    +++  V   G +D+++NNA +M+  +++G      +    ++N   ++ +
Sbjct: 62  NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
             KAI I  +    + G ++N +S   L  +H    Y A+K AV+  +   G    ++ +
Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTG--YMYANS 176

Query: 558 GVRVLTVCLGATDTALLTDEK 620
           G+R   +  G   T + +  K
Sbjct: 177 GIRCNAIAPGGVATNITSSLK 197


>UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2;
           Actinomycetales|Rep: Short chain dehydrogenase -
           Rhodococcus sp. (strain RHA1)
          Length = 267

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 59/190 (31%), Positives = 94/190 (49%), Gaps = 7/190 (3%)
 Frame = +3

Query: 57  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 236
           +TG A G+G  +   L D G   + I D+ EE G++  A+   K G  T F + DVTD+ 
Sbjct: 13  VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRAT-ADSVGKTGVDTGFVKLDVTDDG 70

Query: 237 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 398
           ++   + A V++ GG+D+++NNA +   S+ +       ++  EVN+  +       +  
Sbjct: 71  NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130

Query: 399 MGK-HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
           M    + G GG ++NVSSVAA      +  Y ATKSAV + +    +       GVRV  
Sbjct: 131 MRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKLGYGVRVNC 190

Query: 576 VCLGATDTAL 605
           V  G   T +
Sbjct: 191 VYPGLVATEM 200


>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 262

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 53/192 (27%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           +++KV  ITGAA+GIG +  R+L  EG  H+ + D+ +  G+S+ A+L    G      +
Sbjct: 6   FENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVK 60

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 389
            DV+       ++ A V+  G ID++ NNA +     S+ I     E  +   + S   A
Sbjct: 61  CDVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYA 120

Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
                 H   +G  ++N +S++ L   +    Y A K AV+ ++  +   +H  + G+RV
Sbjct: 121 CHFAIPHM-PRGSAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALA-VDH-GRDGIRV 177

Query: 570 LTVCLGATDTAL 605
             +C G  +T +
Sbjct: 178 NALCPGLVETPI 189


>UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 275

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 60/196 (30%), Positives = 98/196 (50%), Gaps = 6/196 (3%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           ++ KV F+TG  +G+G ++   L   G   IA+ DI  EA + + A +    G K+   +
Sbjct: 4   FQGKVAFVTGGGSGLGRALSEELARRGAV-IAVTDINAEAAEHVAAAITES-GGKSCSMK 61

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITS 377
            DV+  E     +++VV   G +D + NNA ++       +G+  + + I+VN+  ++  
Sbjct: 62  LDVSQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYG 121

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           T  A   M +   G    ++N++SV  L        Y ATK AV+  S  + RPE  SK 
Sbjct: 122 TTAAYSHMVRQGYGH---IVNIASVGGLVPLPTYAAYAATKHAVVGLSTSM-RPE-ASKL 176

Query: 558 GVRVLTVCLGATDTAL 605
           GVR+  VC G  +T L
Sbjct: 177 GVRITVVCPGTMNTGL 192


>UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein;
           n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short
           chain dehydrogenase family protein - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 273

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 61/194 (31%), Positives = 97/194 (50%), Gaps = 6/194 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           DKV  +TG A+G+G +V  +L   G   + I DI  E+ + + A + +  G  T  +  D
Sbjct: 6   DKVFIVTGGASGMGRAVCELLGTRGA-ILIIADIDGESAEKVAAGITAAGGRATGVF-LD 63

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383
            T +E    +++    E G +D + NNA ++      + S   + + ++VN   ++T TL
Sbjct: 64  TTADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTL 123

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            A  IM +   G    +IN +S A L    V+  Y  TK AV+  S  + RPE  +K GV
Sbjct: 124 AAYRIMVEQGFGH---IINTASTAGLVPIPVITAYATTKHAVVGLSISL-RPE-AAKAGV 178

Query: 564 RVLTVCLGATDTAL 605
           RV  VC G   T++
Sbjct: 179 RVSVVCPGYVSTSI 192


>UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9;
           Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas
           sp. (strain NCIMB 9872)
          Length = 250

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 53/166 (31%), Positives = 85/166 (51%), Gaps = 6/166 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           DKVV +TG A G+G +   +L  EG   + + D+ EE G    AE+  + G K  F   D
Sbjct: 6   DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383
           VT+E H+ G ++ ++ E   +D ++NNA ++      + S   + +  E+NV ++   T 
Sbjct: 64  VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 521
             IE M K      G ++NVSS+  L  +     Y A+K AV  F+
Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFT 166


>UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep:
           Lin2278 protein - Listeria innocua
          Length = 253

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 52/197 (26%), Positives = 100/197 (50%), Gaps = 8/197 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGAA+G+G+ +  +   EG K + + D+  EA Q   A +  + G       ++V
Sbjct: 7   KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 383
           T ++    ++N   +  G +D+++NNA +M++ +        ++ K   +N T ++ +T 
Sbjct: 65  TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124

Query: 384 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           KA+ I  +    KG G ++N++S   L  S     Y A+K AV+ F+  +G    ++   
Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVG--FQYANKN 178

Query: 561 VRVLTVCLGATDTALLT 611
           +R   +  GA +T + T
Sbjct: 179 IRCNAIAPGAVNTNIGT 195


>UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2143
          Length = 259

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 55/210 (26%), Positives = 96/210 (45%), Gaps = 5/210 (2%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS  +  +V  +TG A GIG +       EG+ ++ + D+ ++ G+   A + +  GN  
Sbjct: 1   MSTTFSGQVALVTGGAAGIGRTTAAAFAREGL-NVVVADMDKDGGEETVAAIKAAGGNAI 59

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383
            F   DVT E     ++       G +D   NNA +  +  G   K  E    +++   +
Sbjct: 60  -FVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEK-GELSKGTEDEFDSIMAVNV 117

Query: 384 KAIEIMGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
           K + +  KH   +     GGT++N SS+  L  +  M IY A+K AV+  +         
Sbjct: 118 KGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVEN-- 175

Query: 549 SKTGVRVLTVCLGATDTALLTDEKLGTFDK 638
           ++ G+R+  VC G  DT +    ++  FD+
Sbjct: 176 ARNGIRINAVCPGVIDTNMFNRSRM--FDR 203


>UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular
           organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus
           iheyensis
          Length = 256

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           +DKV  +TGAA G+G++   IL  E    + I D  EE GQ +  E+    G +  F + 
Sbjct: 7   EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEVVEEVKQA-GGQAAFIKV 64

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 377
           D++D      ++   V + G +D+ +NNAAL  D           + K I V++T   T+
Sbjct: 65  DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
                E+      G GG+++N+SSV+          Y A K  V+  +  +   E+    
Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTK-VAALEN-GPQ 180

Query: 558 GVRVLTVCLGATDTALL 608
            +RV TV  GA DT +L
Sbjct: 181 NIRVNTVAPGAIDTPML 197


>UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Bacteria|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Pseudomonas putida (strain KT2440)
          Length = 262

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 53/206 (25%), Positives = 97/206 (47%), Gaps = 7/206 (3%)
 Frame = +3

Query: 18  LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197
           + +++++  KVV +TGA +GIG +        G   +A+ DI+ + G     EL    G 
Sbjct: 1   MTVNYDFSGKVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGG 58

Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVN 356
           +  F+  DV  E     +L  VV   GG+D+  NNA +  + + +       +++ I+VN
Sbjct: 59  EATFFHVDVGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVN 118

Query: 357 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536
           ++++       I +M K     GG ++N +S + L   + +  Y ATK  V+  +     
Sbjct: 119 LSSVFYCLKGEIPLMLKRG---GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAA- 174

Query: 537 PEHFSKTGVRVLTVCLGATDTALLTD 614
              ++   +R+  VC G  D+  L D
Sbjct: 175 -IDYANQNIRINAVCPGPVDSPFLAD 199


>UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3;
           Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp.
           SG-1
          Length = 279

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 53/197 (26%), Positives = 97/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           ++K   ITGA +G+G+S    L  EG+  IA++DI EE G     E+  + G    F ++
Sbjct: 31  ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 377
           DV+  E     ++  V+E G +D   NNA +       +N  I   ++ + +N+   +  
Sbjct: 89  DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
                E+M K+    GG+++N +S A +     +  Y ATK  ++  +  +     ++K 
Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSM--VAEYAKE 203

Query: 558 GVRVLTVCLGATDTALL 608
           G+RV  +  G T+T ++
Sbjct: 204 GLRVNAIAPGPTETPMV 220


>UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Bacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Methylobacterium
           sp. 4-46
          Length = 255

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 60/203 (29%), Positives = 97/203 (47%), Gaps = 6/203 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TG A GIG +  R   +EG   + + DI  EAG +  A  N  +    +F   DV
Sbjct: 7   KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 386
           T +  +    +  V  +GG+DVV+N A +      +S+ +  +++   VNV         
Sbjct: 62  TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A+ +M K   G+GG +IN+SSV+ +   H +  Y A+K AV   +  +         G+R
Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGHNLAAYNASKGAVRLLTKSVALHCARQGYGIR 180

Query: 567 VLTVCLGATDTALLTDEKLGTFD 635
             ++  G T+T +L D   G  D
Sbjct: 181 CNSIHPGFTETDMLHDLAAGGRD 203


>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Chloroflexus|Rep: Short-chain
           dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
           9485
          Length = 256

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 6/198 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E++ KV  +TG A GIG +    L  EG   + I D    A  +L   +N+ +G +    
Sbjct: 2   EFQGKVAIVTGGAQGIGRATALALAREGAA-VVIADRDAAATTALVEGINA-WGGRALAV 59

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALIT 374
            +DV+DE     I N  V E GGID+++NNA +       + ++ ++++ I VN+T +  
Sbjct: 60  IADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF- 118

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
             L +  +M +     GG ++NV+SV  L        Y A+K  V+  +  +      + 
Sbjct: 119 --LVSRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDG--AP 174

Query: 555 TGVRVLTVCLGATDTALL 608
            G+RV  VC G  DT+LL
Sbjct: 175 DGIRVNCVCPGLIDTSLL 192


>UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 250

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 50/169 (29%), Positives = 90/169 (53%), Gaps = 7/169 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGAA GIG ++    + EG K + I DI +  GQ + AEL    G +  F+ +DV
Sbjct: 10  KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 383
           +D      +++  ++  GG+ V+ NNA +       ++D +  +++ + V++  ++  + 
Sbjct: 64  SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530
            A   M  H GG    ++N++S A +T    M  Y A K+ V+QF+ C+
Sbjct: 124 SAARHMVDHGGG---AIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCL 169


>UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase;
           n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein
           reductase - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 249

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 59/205 (28%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M+   KDKV  ITG   GIG  +    + EG K +   +   + G++  A    K+G+  
Sbjct: 1   MTDRLKDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAVA----KFGDDV 56

Query: 204 K-FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNV 359
             F + DV+ E  +  +++A + + G +D+++NNA +  +N +I       ++K I+VN+
Sbjct: 57  SLFVQQDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNL 116

Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539
           TA       AI+ M K +    G++INVSSVA L    + P Y A+K      ++     
Sbjct: 117 TANFLGEKAAIKAM-KQTADAKGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALN 175

Query: 540 EHFSKTGVRVLTVCLGATDTALLTD 614
                  +RV +V  G  DT+++ +
Sbjct: 176 LAQRGIDIRVNSVHPGWIDTSIVPE 200


>UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;
           Bacteria|Rep: Short-chain alcohol dehydrogenase -
           Burkholderia dolosa AUO158
          Length = 284

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 60/195 (30%), Positives = 101/195 (51%), Gaps = 7/195 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           +KVV ITGA++GIGE+  ++L  +G   +A+     +  Q + AE+ +K G +   ++ D
Sbjct: 44  NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 383
           VTD+E    ++N VV + G +DV++NNA LM  + + + K     + I++N+  L+    
Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAAL-TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
            A+ +  K    + G  +N++SV  L   S    +Y  TK AV   S  +    H     
Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGLKVFSPGGTVYSGTKFAVRAISEGL---RHEVGGN 215

Query: 561 VRVLTVCLGATDTAL 605
           +R   +  GA DT L
Sbjct: 216 IRTTVISPGAIDTEL 230


>UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=5; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Mycobacterium
           sp. (strain KMS)
          Length = 261

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 61/200 (30%), Positives = 94/200 (47%), Gaps = 8/200 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +V  +TG A+GIG +    L  EG++ + +LDI   A +++ AE     G      R DV
Sbjct: 6   RVALVTGGASGIGRATAGRLAAEGMR-VCVLDIDGPATEAV-AESIGGIG-----LRCDV 58

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND---SIGI-----YKKAIEVNVTALITST 380
           TD E      +  V E GG+DV   NA +  D    IG      Y+K++ VNV  ++   
Sbjct: 59  TDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDGVVFGV 118

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
             A+  M     G    ++  +S+A L   H  P+Y   K  V+ F   I    + +  G
Sbjct: 119 RAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIA--PNLAAEG 176

Query: 561 VRVLTVCLGATDTALLTDEK 620
           + V T+C G T+T +L D +
Sbjct: 177 IAVHTICPGITETGVLGDRR 196


>UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 258

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 60/202 (29%), Positives = 101/202 (50%), Gaps = 8/202 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K+  +TG A+G+G +  R L  EG + +   DI   AG + ++EL    G    F R DV
Sbjct: 6   KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 386
           T E  +L +L  +    G +DV++NNA + ++ +I       + + + VN+ ++      
Sbjct: 64  TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG-- 560
            + +M +    KGG++INVSS+ A+    V   Y A+K+ V   S  +    H ++ G  
Sbjct: 124 GLALMKQ----KGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVAL--HCAEKGYA 177

Query: 561 VRVLTVCLGATDTALLTDEKLG 626
           +RV ++  G  DT LL     G
Sbjct: 178 IRVNSLHPGYIDTPLLAGSNAG 199


>UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep:
           CylG - Streptococcus agalactiae
          Length = 240

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 53/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TG   GIG ++ + L  EG K IAI +  +   ++LQ EL      K   Y+ ++
Sbjct: 2   KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386
           +D +    ++  + +E GGID ++NNA ++ D   +      +   I +N+  L+  +  
Sbjct: 57  SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116

Query: 387 AIEIM-GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            ++IM  K   GK   VIN+SS + +        Y ATK A++  +  + +   F+  G+
Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGIAGQIGQANYSATKGAIISITKTLAK--EFASDGI 171

Query: 564 RVLTVCLGATDTALLTD 614
            +  V  G  +T +  +
Sbjct: 172 TINCVSPGFIETDMTNE 188


>UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=4; Sphingomonas|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Pseudomonas paucimobilis (Sphingomonas paucimobilis)
          Length = 250

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 63/200 (31%), Positives = 98/200 (49%), Gaps = 6/200 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M++    KV  ITG A+G+G +  +   +EG K + I D+ EE  + + AE+ +  G   
Sbjct: 1   MANRLAGKVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDA 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 365
            F R DVTD   +   + A V   GG+  + N A +++      +SI  + K + VN TA
Sbjct: 59  LFIRLDVTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTA 118

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           +      AI  + K SG   G++IN+SS+  +  +     Y ATK+AV   S        
Sbjct: 119 IFLGIKAAIPELVK-SG--NGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAAL--E 173

Query: 546 FSKTGVRVLTVCLGATDTAL 605
           F   GVRV T+  G  +T +
Sbjct: 174 FVDRGVRVNTIVPGGMNTPI 193


>UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep:
           All3753 protein - Anabaena sp. (strain PCC 7120)
          Length = 263

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 60/192 (31%), Positives = 93/192 (48%), Gaps = 6/192 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +   ITGAA+GIG  +V I  +    ++ ++D A+E  + +  E   K+G   K    D+
Sbjct: 7   QTALITGAASGIGYELVCIFAENDY-NLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDL 65

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDS-IGIYKKAIEVNVTALITSTLK 386
           +       I   V Q    +DV++NNA      L ND+ +    + ++VNV      T  
Sbjct: 66  SKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKL 125

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
            ++ M +   GK   ++NVSS AA     +M +YFATK+ VL FS  +        TGV 
Sbjct: 126 FLKNMVQQGEGK---ILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALA--NELDGTGVT 180

Query: 567 VLTVCLGATDTA 602
           V  +C G T +A
Sbjct: 181 VTVLCPGTTQSA 192


>UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20;
           Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Oceanobacillus iheyensis
          Length = 255

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 67/202 (33%), Positives = 100/202 (49%), Gaps = 13/202 (6%)
 Frame = +3

Query: 57  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 236
           +TG A+G+GE+ VR L ++G K +AI D+ +E G+ L  EL    G+   +++ DVTDE 
Sbjct: 10  VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64

Query: 237 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 386
                L+ V+++  GI  V+N A  A+   +IG         +   IE+N+         
Sbjct: 65  SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124

Query: 387 AIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           A E M  +S    G+ G +IN +SVAA         Y A+K  V   +  I R    S  
Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIAR--DLSTL 182

Query: 558 GVRVLTVCLGATDTALLTDEKL 623
           G+RV+T+  G   T L   EKL
Sbjct: 183 GIRVMTIAPGLFLTPLF--EKL 202


>UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2;
           Streptomyces|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 584

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 9/194 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS-D 221
           ++V +TGA +GIG +      + G + +A+   AE A ++  AE++   G    +  + D
Sbjct: 317 QLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAART--AEMSRLIGAPDAWAETVD 374

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 383
           V+DE+    +   V  E G +DV++NNA +       + +   ++K ++VN+  +I    
Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVI---- 430

Query: 384 KAIEIMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
               + GK     G+GG ++N +S AA   S  +P Y  +K+AVL  S C+ R E  +  
Sbjct: 431 HGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL-RAE-LAGQ 488

Query: 558 GVRVLTVCLGATDT 599
           G+ V  +C G   T
Sbjct: 489 GIGVSAICPGFVHT 502


>UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2;
           Bacteria|Rep: Short-chain dehydrogenase -
           Symbiobacterium thermophilum
          Length = 254

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 61/194 (31%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITGAA G+G +   +   EG + + I D+ EE G++ QA      G    F R+DV
Sbjct: 7   KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 404
           +       ++   V   G +DV +NNAA   D+  +     E    A+I   LK + +  
Sbjct: 65  SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123

Query: 405 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           K+        G GG++IN+SSV+ +      P Y A K  V+  +        +S  G+R
Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAM--DYSPHGIR 181

Query: 567 VLTVCLGATDTALL 608
           V  V  GA DT +L
Sbjct: 182 VNAVAPGAVDTPML 195


>UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR)
           family protein; n=1; Thermobifida fusca YX|Rep:
           Short-chain dehydrogenase/reductase (SDR) family protein
           - Thermobifida fusca (strain YX)
          Length = 282

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 57/194 (29%), Positives = 94/194 (48%), Gaps = 5/194 (2%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M+   + +V  ITG A+GIGE+ VR    EG   + I DI  EAG+ L  EL    G++ 
Sbjct: 1   MTQRLRGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRA 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383
            F R+DV++E     +++  V   G +D+++NNA +M  ++G        +    I   L
Sbjct: 56  VFVRTDVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNL 114

Query: 384 KAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
           + +    KH+       + G +I+ SS A +       IY A K  ++  SN +      
Sbjct: 115 RGVICGMKHAARVMKPRRSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVA--AEL 172

Query: 549 SKTGVRVLTVCLGA 590
            + G+RV T+  G+
Sbjct: 173 RQHGIRVNTIIPGS 186


>UniRef50_Q46PX5 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
           NAD-dependent epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 253

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           KDKV  +TG A+GIGE+ VR+   +G   + I D     G+ L  EL S+      +   
Sbjct: 9   KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 377
           DV+ E+    +++  V   G +D+++ NA + + S  +       +++ I+VN+T +  S
Sbjct: 66  DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
              AI  M K   G GG ++N++S+           Y A K  V+  +  +G   H ++ 
Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLG-VSH-AQD 181

Query: 558 GVRVLTVCLGATDTALL 608
           G+RV  VC G   T L+
Sbjct: 182 GIRVNAVCPGFVATPLI 198


>UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Pseudoalteromonas
           atlantica (strain T6c / BAA-1087)
          Length = 270

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 9/198 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K KV+ ITG ATGIG  +V   + +  + +  +D+ EEA  +L ++L+++ G    F   
Sbjct: 26  KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 377
           D T  +     ++++    G +DV+INN A       L  D  G ++  + VN+ +   +
Sbjct: 85  DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
              AI +M      + G +IN+SS+  L     MP Y A KSA+   S  +     + + 
Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVLIGPKQMPGYVAAKSALNGLSKSLA--NQYGEY 198

Query: 558 GVRVLTVCLG--ATDTAL 605
           G+RV T+  G  ATD  L
Sbjct: 199 GIRVNTILPGWVATDRQL 216


>UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase
           SDR - Pelobacter propionicus (strain DSM 2379)
          Length = 283

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 57/206 (27%), Positives = 102/206 (49%), Gaps = 10/206 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITGA  GIG ++   L  +G   + + D+  +    +  E+ ++ G K    R+DV
Sbjct: 24  KVAIITGAGRGIGRAIALRLGADGAAMV-VSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 383
           T E     +++  V++ G +D+++ NA + N  + I      + + + VN   A +  T+
Sbjct: 82  TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141

Query: 384 KAIEIMGK-HSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
            A +++ + HS   G GG +IN +S+AA +   ++  Y A+K AV  F+  + +     K
Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAKELGPYK 201

Query: 555 TGVRVLTVCLGATDTALLTDEKLGTF 632
             V      +  TD   L DEK+G +
Sbjct: 202 INVNAYCPGIVGTDMWTLIDEKMGPY 227


>UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Comamonas testosteroni
           KF-1
          Length = 259

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 59/191 (30%), Positives = 93/191 (48%), Gaps = 6/191 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +   ITGA  GIG +   +   EG   + +   AE   ++ +A L +  G +     +DV
Sbjct: 9   RTALITGAGAGIGAAASHLFCKEGAAVLMVDANAEALERTREAILQAVPGARLACVMADV 68

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITSTLK 386
           +DE      +   VQ+ GG+D ++NNAA+ N S      A E      VN+  +      
Sbjct: 69  SDESAAAAAVGQCVQQWGGLDTLVNNAAMRNYSAAADATAAEWQAMVGVNLVGMSNYCRA 128

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A+  + + SG   G+++NVSS  A+T    M +Y ATK+A L ++  +   E  +  GVR
Sbjct: 129 ALPAL-RQSG--TGSIVNVSSCYAVTGRKGMALYDATKAAQLAYTRSLAFEE--AAHGVR 183

Query: 567 VLTVCLGATDT 599
              VC G+T T
Sbjct: 184 ANAVCPGSTLT 194


>UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain
            dehydrogenase/reductase family protein; n=1; Tetrahymena
            thermophila SB210|Rep: Oxidoreductase, short chain
            dehydrogenase/reductase family protein - Tetrahymena
            thermophila SB210
          Length = 843

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 6/192 (3%)
 Frame = +3

Query: 51   VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230
            V +TGAA G G+ +      +   +I I DI E+    +  E+  K G K  FY+ DV+D
Sbjct: 577  VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635

Query: 231  EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 392
            E+     + + +Q+   ID++INN  + N       S    +KA  VN  A ++   K +
Sbjct: 636  EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695

Query: 393  EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
             +M + + G    ++NVSSVA+L  S  M  Y A+K+A+  F N +       K  +   
Sbjct: 696  PVMIERNQGH---IVNVSSVASLMPSAKMTDYCASKAALSGFHNALRLELKQQKKNINTT 752

Query: 573  TVCLGATDTALL 608
             +C  A +T +L
Sbjct: 753  LICPYAVNTGVL 764


>UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=1; Bacillus halodurans|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus
           halodurans
          Length = 247

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 53/211 (25%), Positives = 101/211 (47%), Gaps = 10/211 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           +DKV  +TGA  GIG+ +V+  +++G     I     EA + ++  LN   G K   Y S
Sbjct: 4   RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61

Query: 219 DVTDEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 377
              D++ F+  +  +VV +   +D+++NNA +  D          +++ ++VN     T 
Sbjct: 62  GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
              A+  M +   GK   ++NV SV  +        Y A+K A++  +  + R   +S+ 
Sbjct: 122 CHAALPYMERKKQGK---IVNVVSVTGVVGREAQTNYGASKGAIIGLTRLLAR--KYSEK 176

Query: 558 GVRVLTVCLGATDTALL---TDEKLGTFDKY 641
           G+ +  +  G  +T ++    +EKL  F ++
Sbjct: 177 GISINAIAPGMIETEMIKQVPEEKLKNFLRF 207


>UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii
           KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
           KSM-K16)
          Length = 247

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 64/207 (30%), Positives = 102/207 (49%), Gaps = 7/207 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E  +KVV ITG A+GIG + V   L +G K + I D  +E G++   EL    G +  F 
Sbjct: 3   ELTNKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFV 60

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALIT 374
           ++DV++E     ++   V+    +D++INNA    M+ S       Y+K ++V    +  
Sbjct: 61  QTDVSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFL 120

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
            +  AI+ M K     GG +IN SS+  ++ Q   +P Y A K AV   +  +     ++
Sbjct: 121 GSKHAIKEMIKTG---GGCIINTSSILGSVAQPEALP-YNAAKGAVNTMTKSLA--VEYA 174

Query: 552 KTGVRVLTVCLGATDTALLTDEKLGTF 632
              +RV  V  G  +TA +  E LG F
Sbjct: 175 DKQIRVNAVAPGFVETAAVNKEALGDF 201


>UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
           Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase
           - Pseudoalteromonas haloplanktis (strain TAC 125)
          Length = 262

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 58/210 (27%), Positives = 102/210 (48%), Gaps = 6/210 (2%)
 Frame = +3

Query: 18  LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197
           +K +    +KV  +TGAA GIG ++ + L+D G   IA   + EE  Q  Q     + G+
Sbjct: 1   MKNATHLTNKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGD 55

Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNV 359
           K      DVTDE  +  I++A +++   ID+++NNA ++            ++K I++N+
Sbjct: 56  KVTPMTHDVTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINI 115

Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539
           T         I  M K +G   G ++N+SS +++  ++    Y A+K AV   +      
Sbjct: 116 TGTFLGLHSVIPCM-KKAG--SGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAAL- 171

Query: 540 EHFSKTGVRVLTVCLGATDTALLTDEKLGT 629
                 G+RV +V  GA +T +   + L +
Sbjct: 172 -ELGPFGIRVNSVHPGAVNTPMTNPQGLSS 200


>UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Leeuwenhoekiella blandensis MED217
          Length = 257

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 47/167 (28%), Positives = 87/167 (52%), Gaps = 6/167 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K+KV  +TG A+G+G+S  ++L  EG K I + DI EE G+ +  ++    G +  F + 
Sbjct: 5   KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKVVQQIKED-GGEAIFIKQ 62

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 380
           DV  E+ +  ++   ++  G + ++ N+A +     + D ++  +K  I++N+      T
Sbjct: 63  DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 521
              I+  G     +GG++IN SS+  L     +P Y A+K  V  F+
Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFT 167


>UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep:
           Short chain dehydrogenase - Mycobacterium avium (strain
           104)
          Length = 594

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 57/195 (29%), Positives = 93/195 (47%), Gaps = 6/195 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E + ++  +TGA  GIG +    L  +G + + I+D  + A     A+     G     Y
Sbjct: 322 EVRGRLALVTGAGAGIGRATAVELARQGARKVVIVD-RDRAAADQTADAVRAAGAGAAVY 380

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392
           + DV+DE     +   V  E G +D+++NNA +     G + +    N  A++   ++ +
Sbjct: 381 QVDVSDEAAMNDLAAQVRNEHGVVDILVNNAGI--GMAGRFLETSPANWDAIMGVNVRGV 438

Query: 393 EIMGKHSG------GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
               +  G      G+GGT+INV+S AA   S  M  Y  TK+AVL  S  + R + F+ 
Sbjct: 439 IWGSRAFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESL-RAD-FAD 496

Query: 555 TGVRVLTVCLGATDT 599
            G+ V  VC G  +T
Sbjct: 497 EGITVTAVCPGFVNT 511


>UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=4; Shewanella|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Shewanella sp.
           (strain ANA-3)
          Length = 292

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 54/200 (27%), Positives = 98/200 (49%), Gaps = 7/200 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GQSLQAELNSKYGNKTKFYR 215
           K KV  ITG+ +GIG +   +L ++G  H+ +  +  EA G+ L AE   +Y   T F  
Sbjct: 35  KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 377
           +D+ D E     ++A V+  G ID+++NNA + +        I  +   I +N+++   +
Sbjct: 94  ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
             +A+  M +    + G +IN++SV  L  S     Y A K  ++  +  +      ++ 
Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVA--IECAEQ 208

Query: 558 GVRVLTVCLGATDTALLTDE 617
           G+ V  +C G  DT L+  +
Sbjct: 209 GITVNAICPGWVDTPLINKQ 228


>UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2;
           Euryarchaeota|Rep: Predicted short chain dehydrogenase -
           Methanosphaera stadtmanae (strain DSM 3091)
          Length = 253

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 59/206 (28%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K KV  ITGA  GIG+S+  +  +EG   I I    E   Q +  E+NS  G+ +     
Sbjct: 4   KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERLEQ-ITNEINSNGGDASACI-G 61

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 377
           DVT +E    ++   + + G ID+++NNA +M+D + +       + K I+VN+T  +  
Sbjct: 62  DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
               I  M K++   GG +I +SSV  L        Y A+K  V+  +        + K 
Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV--YGKH 176

Query: 558 GVRVLTVCLGATDTALLTDEKLGTFD 635
            +R   +  G  +T + T    G  D
Sbjct: 177 NIRSNVIAPGTVNTEIATTINPGRMD 202


>UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;
           n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase
           SSP0419 - Staphylococcus saprophyticus subsp.
           saprophyticus (strain ATCC 15305 /DSM 20229)
          Length = 234

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 59/209 (28%), Positives = 104/209 (49%), Gaps = 7/209 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGQSLQAELNSKYGNKTKF 209
           E +DKV  +TGA++GIG S+   L ++GVK +    D +  A  + + + N +   +T  
Sbjct: 3   ELQDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSI 62

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALI 371
              DVT +E    ++    ++ G ID+++N+A LM  S      +  ++  I+VN+   +
Sbjct: 63  V--DVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTL 120

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
            +    +  M   S G    +IN++S++    +    +Y A+K+AV   +   G  +  +
Sbjct: 121 YTINAVLPSMLNQSSGH---IINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKELA 175

Query: 552 KTGVRVLTVCLGATDTALLTDEKLGTFDK 638
           KTGVRV ++  G  DT L  D   G   K
Sbjct: 176 KTGVRVTSISPGMVDTPLSGDTDWGARKK 204


>UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member
           11 precursor; n=7; Eukaryota|Rep:
           Dehydrogenase/reductase SDR family member 11 precursor -
           Gallus gallus (Chicken)
          Length = 255

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 57/197 (28%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSK-YGNKTKFY 212
           W  +V  +TGA+ GIG +V R L+  G+K +      ++  + L AE  S  Y      Y
Sbjct: 4   WTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKI-EKLAAECQSAGYPGTLIPY 62

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 374
           + D+++EE  L + +A+     G+DV INNA       L++     ++  I+VNV A+  
Sbjct: 63  KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSI 122

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSV--AALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
            T +A + M K      G +IN++S+   ++    V+  Y ATK AV   +  + +    
Sbjct: 123 CTREAYQSM-KERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELRE 181

Query: 549 SKTGVRVLTVCLGATDT 599
           +KT +R   +  G  +T
Sbjct: 182 AKTHIRATCISPGLVET 198


>UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase;
           n=1; Burkholderia xenovorans LB400|Rep: Putative
           short-chain type dehydrogenase - Burkholderia xenovorans
           (strain LB400)
          Length = 252

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 63/199 (31%), Positives = 93/199 (46%), Gaps = 6/199 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M+     K + ITGA   IG+   R  + EG + + I DIAEEAG+++ AEL    G   
Sbjct: 1   MAGRLSGKRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAA 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383
            F + DVT E     ++   V+  GG+D +  NA L     G      + N  AL     
Sbjct: 56  HFVQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNA 113

Query: 384 KAIEIMGKHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           +A     KH+       GK G++IN+SS+A       +  Y A+K AV+ F+  +     
Sbjct: 114 RAHFFGAKHAIPHLQRSGK-GSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALAL--E 170

Query: 546 FSKTGVRVLTVCLGATDTA 602
            +   +RV  +C G  DTA
Sbjct: 171 LAPDNIRVNAICPGWVDTA 189


>UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Mesorhizobium sp. BNC1|Rep: Short-chain
           dehydrogenase/reductase SDR - Mesorhizobium sp. (strain
           BNC1)
          Length = 257

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS-D 221
           KV  +TGAA G+GE++   L  +G + +A+LD+ +E G  +   +    GN   +YR+ D
Sbjct: 7   KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGNA--YYRNCD 63

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 392
           + D E     ++ V    G +DV++NNAA+      I + + E   N+  +  S++    
Sbjct: 64  IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123

Query: 393 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
             ++ +     GG VIN+SSV           Y ATK A++  S  +     + +  +RV
Sbjct: 124 RFVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLA--AEWGRFNIRV 181

Query: 570 LTVCLGATDTAL 605
            TV  GA D  +
Sbjct: 182 NTVSPGAIDATM 193


>UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;
           n=11; cellular organisms|Rep: Uncharacterized
           oxidoreductase TM_0019 - Thermotoga maritima
          Length = 256

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 53/192 (27%), Positives = 96/192 (50%), Gaps = 6/192 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TG   GIG ++ ++  + G+K + I +I EEAG   +  L  + G    F ++DV
Sbjct: 5   KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 386
            DE     ++   V+  GG+DV++NNAA+M+        +  +++ I VN+T     +  
Sbjct: 63  ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
             E M K     GG +IN++S  A         Y A+K  ++  ++ +      S+  +R
Sbjct: 123 CAEEMIKRG---GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA--VSLSRYHIR 177

Query: 567 VLTVCLGATDTA 602
           V+++  G  +T+
Sbjct: 178 VVSISPGWIETS 189


>UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus
           iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
          Length = 257

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 59/199 (29%), Positives = 106/199 (53%), Gaps = 7/199 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           +++DKV+ +TGAA GIG+ VVR + +   K + ++D+ E+A +S+QAEL     N +   
Sbjct: 3   KFQDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVV 60

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 371
           ++DV++EE+    ++  + + G ID  +NNA +   +  I       +     +NV  ++
Sbjct: 61  KADVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVL 120

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
                 + +M      K G+++N +SVA L  S  M +Y ++K AV+   N +   E  +
Sbjct: 121 FGLKYVLPVM---KAQKSGSIVNTASVAGLIGSPSMALYNSSKHAVMGL-NKVAALES-A 175

Query: 552 KTGVRVLTVCLGATDTALL 608
              VRV TV  G  +T ++
Sbjct: 176 AFNVRVNTVNPGVINTQMM 194


>UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=6; Desulfuromonadales|Rep: 3-oxoacyl-(Acyl
           carrier protein) reductase - Geobacter sulfurreducens
          Length = 246

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 5/214 (2%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E+KD +V +TG   GIG ++      +G    A     +EA ++L+AE     G+     
Sbjct: 2   EFKDSIVVVTGGTRGIGRAISLHFARQGALVTAAYRADDEAARALEAEAAGLPGS-IAVI 60

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392
           R+DV   E  + +++A   E G + V++NNA ++ D  G      E +  A++ + L  +
Sbjct: 61  RADVGTAEGAMAVIDAASGESGTLHVLVNNAGIIRD--GYLAMMAEDDWDAVMRANLSPL 118

Query: 393 EI-----MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
                  + K    + G +IN+SSV+A   +     Y ATK A + F+  + R       
Sbjct: 119 FHCCKWGVRKMLARRRGAIINLSSVSAFAGTAGQTNYAATKGAAVSFTKSLAR--EVGPL 176

Query: 558 GVRVLTVCLGATDTALLTDEKLGTFDKYLXSSCL 659
           G+RV  V  G  +T ++   K    D+ + SS L
Sbjct: 177 GIRVNAVAPGLIETEMIAGMKREMVDRIVGSSIL 210


>UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Staphylococcus
           epidermidis|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Staphylococcus
           epidermidis (strain ATCC 35984 / RP62A)
          Length = 255

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 54/188 (28%), Positives = 100/188 (53%), Gaps = 7/188 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  + G ATGIG+++   L   G  +I I D+    GQ     ++++ G KT   + D+
Sbjct: 13  KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 392
           T  +    I++ VV+E G ID+++NNA  ++ +D+  I Y++ + E+N++  +       
Sbjct: 72  THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129

Query: 393 EIMGKHSGGKG-GTVINVSSVAAL--TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
           + +G+    KG G++INVSSV  L   ++     Y  +K+ V   +  + R   +S+ G+
Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLAR--EWSRYGI 187

Query: 564 RVLTVCLG 587
           +V  +  G
Sbjct: 188 KVNAIAPG 195


>UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3;
           Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase -
           Eubacterium sp. (strain VPI 12708)
          Length = 266

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 52/211 (24%), Positives = 105/211 (49%), Gaps = 10/211 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           KDKV+ +T +  GIG ++ +    EG K ++   ++  E  ++   E+N+  GN  K+  
Sbjct: 4   KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 368
           +D T EE ++ ++  +++++G IDV++NN           + N    ++ K + +N+ ++
Sbjct: 61  NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120

Query: 369 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
             ++  A++ M ++    GG++IN+SSV  L        Y  +K+A+   +  I    H 
Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIA--VHE 175

Query: 549 SKTGVRVLTVCLGATDTALLTDEKLGTFDKY 641
           ++  +R   V  G T T  + D     F  +
Sbjct: 176 ARHNIRCNAVLPGMTATDAVQDNLTDDFRNF 206


>UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Bacillus sp. B14905
          Length = 254

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 54/195 (27%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           ++KV  ITG  TGIG+    +   EG K I I DI E++G    +++ + +G +  F   
Sbjct: 7   ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 380
           DV++E+ +  + +  +     +D++ NNA       L    +  + + + +NVT +    
Sbjct: 65  DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
              + +M K +    G+VIN SS+A LT +    +Y A+K AV   +        ++  G
Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLTGAAGHVLYGASKGAVRIMTK--DAAMEYAPYG 179

Query: 561 VRVLTVCLGATDTAL 605
           VRV ++  G  DT +
Sbjct: 180 VRVNSIHPGYIDTGM 194


>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
           n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
           TM_0325 - Thermotoga maritima
          Length = 251

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 60/194 (30%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           ++ KVV ITGA +GIG+    +  + G K +AI DI+EE G+    EL    G +  F  
Sbjct: 3   FQGKVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIF 60

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITS 377
            DV  +     I+   V+  G +D+++NNA ++        S   + K + VNV      
Sbjct: 61  GDVAKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           +  A+E M K     GG ++NVSS A L       +Y  +K+A+L  +  +     +   
Sbjct: 119 SKYAVEQMKKQG---GGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLA--VDYVDY 173

Query: 558 GVRVLTVCLGATDT 599
           G+RV  VC G T +
Sbjct: 174 GIRVNAVCPGTTQS 187


>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Leptospira interrogans
          Length = 259

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 53/199 (26%), Positives = 101/199 (50%), Gaps = 7/199 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197
           MS +++ KV  +TGAA+  G+G ++   +  EG   I ++D+ +E  +   A++  ++G 
Sbjct: 5   MSKQFEGKVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGV 63

Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 377
           KT     +VT  E    ++  V ++ G +D ++NNA ++ D++ I  +  E     ++  
Sbjct: 64  KTLGLSCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDV 121

Query: 378 TLKAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542
            LK + +M K++       + G ++N+SSV+ LT       Y ++K+ V+  +    R  
Sbjct: 122 NLKGVFLMTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR-- 179

Query: 543 HFSKTGVRVLTVCLGATDT 599
            F+   V V  VC G   T
Sbjct: 180 EFAGRNVLVNAVCPGYVQT 198


>UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 595

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 60/201 (29%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
 Frame = +3

Query: 27  SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGQSLQAELNSKYGNKT 203
           S  +  KV  +TGA +GIG         EG   +A  +D+A     +L   L    G + 
Sbjct: 322 SGRFSGKVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAERTALLIGLT---GAQA 378

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTA 365
              R DV   +    +   V    GG DVVINNA +      ++ S   +++ + VN+  
Sbjct: 379 HAKRVDVGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWG 438

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           +I  +    + M     G GG ++N +S AA   S  +P Y  TK+AVL  S C+ R E 
Sbjct: 439 VIHGSRLFAQQMAAR--GTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM-RAE- 494

Query: 546 FSKTGVRVLTVCLGATDTALL 608
            ++ G+ V  VC G  +T ++
Sbjct: 495 LAEQGIGVTAVCPGFAETGIM 515


>UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1;
           marine gamma proteobacterium HTCC2143|Rep: Short-chain
           dehydrogenase/reductase - marine gamma proteobacterium
           HTCC2143
          Length = 264

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 60/200 (30%), Positives = 101/200 (50%), Gaps = 6/200 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M++  + KV  ITG  +GIGE+   I + EG   + +   +EE GQ++   L    G+K 
Sbjct: 1   MTNRLQGKVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIANRL----GDKA 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTA 365
            + ++DV+ EE     ++  V+  G +DV+ NNA        DSI  G     +++ +++
Sbjct: 56  HYIKADVSKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSS 115

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           ++     AIE M K +G  GG +IN +S+AA+       +Y A K+AV  ++   G    
Sbjct: 116 VVLGIRYAIEPM-KANG--GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAG--VE 170

Query: 546 FSKTGVRVLTVCLGATDTAL 605
               G+RV  +  GA  T +
Sbjct: 171 LGPLGIRVNCISPGAIATPI 190


>UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyces
           coelicolor|Rep: Putative dehydrogenase - Streptomyces
           coelicolor
          Length = 276

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 54/197 (27%), Positives = 99/197 (50%), Gaps = 7/197 (3%)
 Frame = +3

Query: 30  HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 209
           HE+ +    +TGA+ G+GE+  R L   G  H+ ++  + +A  +L  E+ + +  +   
Sbjct: 2   HEYTNTTALVTGASKGLGEAYARELASRGA-HLVLVARSADALHALADEIRATHSVRVDV 60

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 371
             +D++D      +L+AV      +D+++NNA +      +   +    ++++VNVTAL+
Sbjct: 61  IAADLSDRRSPQRVLDAVDGLGLDVDLLVNNAGMGAVGPFLVRPLAPNLQSVDVNVTALV 120

Query: 372 TSTLKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
                 + ++G     +G G ++N++S AA         Y ATK+ VL F+  +   E  
Sbjct: 121 ----GLVHLLGARMVERGRGGIVNIASTAAFQPMPYQASYAATKAFVLSFTEAVA--EEV 174

Query: 549 SKTGVRVLTVCLGATDT 599
             TGVRV+    GAT T
Sbjct: 175 RGTGVRVMAAHPGATAT 191


>UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 261

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 61/196 (31%), Positives = 94/196 (47%), Gaps = 7/196 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           +D+VV ITG   GIG ++ R +  EG     I+   +E      A+   + G     +  
Sbjct: 28  EDQVVLITGGNRGIGLAMARAVAKEGAS--VIITGRDEHTLHHAADQIKRDGGTVVSHVC 85

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 377
           DV DE+    +  A+ +    IDV++NNA L          S+  ++  IE N+T     
Sbjct: 86  DVRDEDSVDELFAAIHRHYSQIDVLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLC 145

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           T  A+ +M       G TV+N  SVAA T    M  Y A+K+ +L F+N +   E     
Sbjct: 146 TRAALPMMSP-----GATVVNNVSVAANTAFPGMAAYSASKAGLLAFTNTL--REELRPR 198

Query: 558 GVRVLTVCLGATDTAL 605
           G+RV+++  GATDT +
Sbjct: 199 GIRVISLVPGATDTEI 214


>UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 252

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 59/191 (30%), Positives = 89/191 (46%), Gaps = 6/191 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITG ATGIG +   +   EG   + I DI EE G S   E     G    F R DV
Sbjct: 7   KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386
           + EE    ++ A  +E G +DVV  NA L+        S   ++  + +N+TA    T  
Sbjct: 65  SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A  +M +H   +GG++I ++S   L  +     Y A+K  ++  +  +   +  +   +R
Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLA--DELAPHNIR 179

Query: 567 VLTVCLGATDT 599
           V  VC G  DT
Sbjct: 180 VNCVCPGWVDT 190


>UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=3; Clostridium
           perfringens|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Clostridium perfringens
           (strain ATCC 13124 / NCTC 8237 / Type A)
          Length = 272

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 56/197 (28%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           + DKV+ ITGAA GIG++V      EG K + + D  EE  +    E+     N  +F  
Sbjct: 9   FSDKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLI 66

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALIT 374
            D+ + E+   +++  +++ GG+D++INNA +          S  +++  ++ N+     
Sbjct: 67  CDLREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFH 126

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
            +   I+ M K +  KGG ++NVSSVA LT       Y  +K  +   +  +     +++
Sbjct: 127 CSHYGIQEMIKQN--KGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMAL--DYAR 182

Query: 555 TGVRVLTVCLGATDTAL 605
            G+RV  V  G TDT +
Sbjct: 183 YGIRVNAVNPGTTDTPM 199


>UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 246

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 56/193 (29%), Positives = 93/193 (48%), Gaps = 6/193 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K+  +TGA  GIG+++   L  EG   + + D+  +A +   A L+    +      +DV
Sbjct: 7   KIAVVTGAGQGIGKAIATKLAAEGAT-VVVTDVDHQAAKETAAALD----HGAIGLHADV 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 386
           TD      +++ VV   G IDV++NNA      A ++     + + I +N+  ++ ++ K
Sbjct: 62  TDRTSVDAMVDEVVATFGRIDVLVNNAGWDKGEAFVDSEPETWDRIIGINLYGVLNTSKK 121

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
            + IM        G+V+N+ S A    S    +Y A K  V+ FS    R    +++ V 
Sbjct: 122 VLPIMAAQG---SGSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAR--EMARSQVN 176

Query: 567 VLTVCLGATDTAL 605
           V  VC G TDTAL
Sbjct: 177 VNCVCPGPTDTAL 189


>UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Chlorobium/Pelodictyon group|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Chlorobium phaeobacteroides (strain DSM 266)
          Length = 280

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 58/199 (29%), Positives = 99/199 (49%), Gaps = 6/199 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K   +TGAA+GIG ++   L++ G + + + DI     +   A L +     T     DV
Sbjct: 8   KNAIVTGAASGIGFALAVGLIERGAR-VWVADIDSAGVERAAASLGAGAHPVTL----DV 62

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386
            D   F  ++  V ++ GGID + NNA +++             + I+VN+  ++  TL 
Sbjct: 63  RDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTLA 122

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A  +M +    + G ++N +S+A L  + ++  Y  TK AV+ FS+ + R E   + GVR
Sbjct: 123 AYPLMVRQ---RSGHIVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL-RFE-AERYGVR 177

Query: 567 VLTVCLGATDTALLTDEKL 623
           V  +C    DT LL +E +
Sbjct: 178 VSAICPAGVDTPLLDEEAI 196


>UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Delftia acidovorans SPH-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Delftia acidovorans SPH-1
          Length = 301

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 60/201 (29%), Positives = 97/201 (48%), Gaps = 6/201 (2%)
 Frame = +3

Query: 18  LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197
           +K   ++  K V +TGA+ GIGE   R L   G K + ++  + +  + L +EL      
Sbjct: 42  MKTPFDFSQKTVLVTGASMGIGEVFARELARRGAK-VVLIARSRDRLEKLASELPG---- 96

Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNV 359
             +F   D+        + +AV       D+++NNA           ++ + ++ I++NV
Sbjct: 97  -AEFLVEDLATPGAARRVFDAVSARGLLPDLLVNNAGFGTHGRFDELALDMQRETIDLNV 155

Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539
            AL+  T   +  + +  GG    VIN++S AA      M +Y ATK+ VL FS  +   
Sbjct: 156 GALVELTHLCLPALEQRQGG----VINIASTAAFQPVPYMAVYAATKAFVLSFSEALW-- 209

Query: 540 EHFSKTGVRVLTVCLGATDTA 602
             +   GVRVL +C GATDTA
Sbjct: 210 AEYRPRGVRVLALCPGATDTA 230


>UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular
           organisms|Rep: Os07g0664000 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 572

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 62/210 (29%), Positives = 94/210 (44%), Gaps = 10/210 (4%)
 Frame = +3

Query: 9   YGTLKMSHE-WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS 185
           + T   SH+    KV  ITG A+GIG++     +  G K + I DI ++ G S+ AEL  
Sbjct: 301 FSTASSSHQRLAGKVAVITGGASGIGKATATEFIKNGAK-VIIADIQDDLGHSVAAEL-- 357

Query: 186 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA----ALMND-----SIGIYK 338
             G    + R DV DE      +   V+  G +DV  NNA    AL  D      +G + 
Sbjct: 358 --GPDAAYTRCDVADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFD 415

Query: 339 KAIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQF 518
           + + VN  + + +   A   M        G V+  SS A +     +P+Y  +K+ V+  
Sbjct: 416 RVMAVNARSTLAAVKHAARAMAPRC---SGCVLCTSSGAGVIPVPAVPVYSVSKATVIAI 472

Query: 519 SNCIGRPEHFSKTGVRVLTVCLGATDTALL 608
                 P   ++ G+RV  +  GAT T LL
Sbjct: 473 VRAAAEP--MARHGLRVNAISPGATRTPLL 500


>UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Methanoregula boonei 6A8|Rep:
           Short-chain dehydrogenase/reductase SDR - Methanoregula
           boonei (strain 6A8)
          Length = 253

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 53/198 (26%), Positives = 94/198 (47%), Gaps = 6/198 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV+ +TGA+ GIG +   +      + I       +  +SL +E+ +  G+     R+DV
Sbjct: 12  KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 386
           T EE    +   + ++ G +D+++NNA +M ++      I  Y+  ++VN       T  
Sbjct: 71  TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A +IM +    K GT+IN++SV  +  +     Y ++KS V+ F+ C  +        + 
Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAK--ELGAFNIT 185

Query: 567 VLTVCLGATDTALLTDEK 620
           V  V  G  DT L  D +
Sbjct: 186 VNAVAPGFIDTDLTADTR 203


>UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Short-chain dehydrogenase/reductase SDR - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 253

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 51/173 (29%), Positives = 95/173 (54%), Gaps = 10/173 (5%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           DKV  +TGA++ IG+ + +  ++EG K I I    E   ++ + E+ ++  + T     D
Sbjct: 5   DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 380
           + DE   L ++N ++   G ID+++NNA  +ND I  +       +K I VN+  +   T
Sbjct: 62  LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVA---ALTQSHVMPIYFATKSAVLQFSNCI 530
            KA  ++ K +  K G+++N+ S++   A+ + H + +Y ATK+A+  F+  I
Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISSERAIPRVH-LAVYSATKAAIPMFTKSI 170


>UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Thermotoga|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Thermotoga maritima
          Length = 257

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 8/198 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K KV  +TG   GIG+++ + L   G   + I+DI EE  +    E+  K G +  FY  
Sbjct: 11  KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 380
           DVT EE   G +   +   G +D+ +NNA +       N  +  +KK I+VN+  +  S 
Sbjct: 69  DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
                 M +   GK   +IN++S++   + +      Y A+K+ V+  +  +     ++ 
Sbjct: 129 KAEFHAMKERKYGK---IINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA--AEWAP 183

Query: 555 TGVRVLTVCLGATDTALL 608
            G+RV ++  G   T L+
Sbjct: 184 YGIRVNSISPGYIRTPLI 201


>UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular
           organisms|Rep: Alcohol dehydrogenase - Bordetella
           parapertussis
          Length = 252

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 55/195 (28%), Positives = 91/195 (46%), Gaps = 5/195 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K   +TGA +G GE +      EG K + + DI E  GQ + A +N+  G +  F R+DV
Sbjct: 6   KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 404
           +D      +L A ++  GG+D+V+NNA   + +  +  +  E     +    +K+I +  
Sbjct: 64  SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122

Query: 405 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
           +H         GG+ IN++S AA+     +  Y  +K AV+  S  +          V  
Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNC 182

Query: 570 LTVCLGATDTALLTD 614
           +   +GA  T LL D
Sbjct: 183 VNPVIGA--TGLLAD 195


>UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Pseudoalteromonas haloplanktis (strain TAC
           125)
          Length = 247

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 6/203 (2%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M H+  D+VV +TGA  GIG+S+V      G  ++A +DI  +   +   ELN+      
Sbjct: 1   MKHQ--DQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNI 57

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365
               +++   +     + AVV++ G +D +IN A      A ++     + K I VN+T 
Sbjct: 58  VAITANIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTG 117

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
                 +A ++M        G +INVSS AALT       Y A+K+ V+  +  + R   
Sbjct: 118 TFLCCREAAKVMQAQG---SGCIINVSSTAALT-GEGPSHYCASKAGVMGLTRSMAR--E 171

Query: 546 FSKTGVRVLTVCLGATDTALLTD 614
            +  G+RV T+  G T+T ++ D
Sbjct: 172 LAPVGIRVNTIVPGPTNTPMMAD 194


>UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 262

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 48/164 (29%), Positives = 83/164 (50%), Gaps = 7/164 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           + KV  ITG A GIG    R L   G   +AILD+  +  ++L  E+ ++ G +  F+  
Sbjct: 11  RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 377
           DVT E     +   +V   G +DV++NNA +   ++         +++ ++VNV  +   
Sbjct: 69  DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 509
           T  AI  +       GG+++N+SS+  +     +P Y A+K+AV
Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAV 169


>UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4;
           Legionella pneumophila|Rep: Acetyoacetyl CoA reductase -
           Legionella pneumophila (strain Corby)
          Length = 248

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 54/196 (27%), Positives = 93/196 (47%), Gaps = 7/196 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGQSLQAELNSKYGNKTKFYRS 218
           + VV ITG    IG +V +  LD   KH+  LD+   + G+    +L ++      F   
Sbjct: 4   NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 380
           DVTD E    ++  +++E GGIDV+INNA +  D++        + + + VN+  +   T
Sbjct: 63  DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
            + +E M     G+   ++NVSSV A         Y A+K+ V  F+  +   +      
Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNAQKGQFSQANYAASKAGVYGFTKSLA--QELMIKN 177

Query: 561 VRVLTVCLGATDTALL 608
           + V ++  G  +T L+
Sbjct: 178 ITVNSISPGYVNTRLM 193


>UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1;
           Flavobacteriales bacterium HTCC2170|Rep: Probable
           glucose 1-dehydrogenase - Flavobacteriales bacterium
           HTCC2170
          Length = 268

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 5/198 (2%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K K V +TG + GIG  + R L   G +     +  E++ Q L  E+++ YG +T    +
Sbjct: 7   KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398
           DV+  E    +   +    GGID+++NNA    +SI      +E     +I   LK   +
Sbjct: 67  DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124

Query: 399 MGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
             K +G +     GG +IN+SS+  +     +  Y + K+ +   S C+      ++  +
Sbjct: 125 CSKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSL--ELAENNI 182

Query: 564 RVLTVCLGATDTALLTDE 617
           RV++V  GA  T +  DE
Sbjct: 183 RVVSVAPGAISTEMNRDE 200


>UniRef50_Q2U0U8 Cluster: Dehydrogenases with different
           specificities; n=2; Pezizomycotina|Rep: Dehydrogenases
           with different specificities - Aspergillus oryzae
          Length = 271

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 59/215 (27%), Positives = 102/215 (47%), Gaps = 23/215 (10%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN------KTKF 209
           +  ITGAA+GIG +       +G   IA+LD+ + A +++QAE+NS+         + + 
Sbjct: 6   IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTARCRVEI 65

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-------YKKAIEVNVTA 365
           Y  +VTDE     ++N+  Q    +D V+N A + M    G        +++ ++VN+T 
Sbjct: 66  YPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRILDVNLTG 125

Query: 366 LITSTLKAIEIMGKHS------GGK---GGTVINVSSVAALTQSHVMPIYFATKSAVLQF 518
                  A  IM           G+    G+++N SS+  +    +   Y ATK AV+  
Sbjct: 126 TFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATKHAVIGL 185

Query: 519 SNCIGRPEHFSKTGVRVLTVCLGATDTALLTDEKL 623
           +      E ++K G+R+  +C G T+T + T   L
Sbjct: 186 TRTAS--EDYAKDGLRINAICPGYTETPMTTKSPL 218


>UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -
           Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 249

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 58/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K+  +TGA++GIG +    L + G K + I     +  + L+ ++ +K G +      DV
Sbjct: 7   KIALVTGASSGIGAATAAKLAEAGAK-VGIAARRTDKLEDLKKKIEAK-GGEALVIEMDV 64

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALM--ND----SIGIYKKAIEVNVTALITSTLK 386
            D       +  +V   G ID+++NNA LM  +D     +  +++ ++VNV  L+ +T  
Sbjct: 65  VDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAA 124

Query: 387 AI-EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            + +++ +HS    G V N+SS+A       + +Y ATK AV  FS+ + R E   K G+
Sbjct: 125 VLPQMIKQHS----GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGL-RMEVGQKHGI 179

Query: 564 RVLTVCLGATDTAL 605
           RV  +  GA  T L
Sbjct: 180 RVTCIQPGAVATEL 193


>UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Chromobacterium violaceum
          Length = 246

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 55/196 (28%), Positives = 95/196 (48%), Gaps = 6/196 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K KV  ITG+A+GIG++     + EG   +A+ D+  +A +++  EL +  G +   Y+ 
Sbjct: 4   KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 380
           DVTD+     ++  +    G IDV++NNA ++ D+  I      + K I++N+  +    
Sbjct: 62  DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
              ++ M +     GG ++N SSV  +  +     Y A K  V+ F     +     K G
Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAK--ELGKKG 176

Query: 561 VRVLTVCLGATDTALL 608
           +R   VC G   T +L
Sbjct: 177 IRANAVCPGFVATPIL 192


>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family; n=1; Photobacterium
           profundum|Rep: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family - Photobacterium
           profundum (Photobacterium sp. (strain SS9))
          Length = 255

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 55/194 (28%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  I+G  +GIGE+  R+   +G   + ++   E  GQ L  ELN++Y   T F ++D+
Sbjct: 10  KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 383
           T       +    + E GGID   NNA        +   S  I+ + I  N+        
Sbjct: 67  TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
           + + IM K      GT++N++S+ ++        Y  ++ AVL  +        ++K GV
Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTR--SAAVEYAKQGV 181

Query: 564 RVLTVCLGATDTAL 605
           RV  V  GA DT +
Sbjct: 182 RVNAVAPGAIDTPI 195


>UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii
           KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
           KSM-K16)
          Length = 257

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 54/199 (27%), Positives = 104/199 (52%), Gaps = 8/199 (4%)
 Frame = +3

Query: 15  TLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG 194
           T+    +   K   +TG A G+G ++ + L   G   IAI+DI  EA      E+ + Y 
Sbjct: 2   TVSTIFDLSTKHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYS 60

Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVN 356
             T+  ++DV+ EE    +++ V++    IDV++NNA ++   D++ +    +K+ ++VN
Sbjct: 61  VNTQSIQADVSKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVN 120

Query: 357 VTALITSTLKAIEIMGKHSGGKG-GTVINVSSVAA-LTQSHVMPIYFATKSAVLQFSNCI 530
           + AL  ++ +    +GKH    G G+++N+SS++A +        Y A+K AV   +  +
Sbjct: 121 INALFLTSKQ----VGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSL 176

Query: 531 GRPEHFSKTGVRVLTVCLG 587
                +++ G+RV  +  G
Sbjct: 177 A--SEWAQYGIRVNAIAPG 193


>UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=3; Frankia|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Frankia sp.
           (strain CcI3)
          Length = 291

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 58/195 (29%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
 Frame = +3

Query: 57  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 236
           ITGA++GIG +      D G + + +   +E     +   L ++YG +      D+ DE 
Sbjct: 14  ITGASSGIGAAFAEAYADRGARLVLVAP-SEPRLWMVAERLGARYGTEAHVIAVDLADER 72

Query: 237 HFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNVTALITSTLKAIEIMG 404
               +  AV +    +D+++NNA          +   +   EV +  +    +  + + G
Sbjct: 73  GPDRLAEAVAEAGLEVDILVNNAGFGTRGPYHELSADRDHREVMLNVVAVERVAHLFLPG 132

Query: 405 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCL 584
             + G+G TVINVSS +       M +Y A+K+ VL FS  IG    + + GVRVL +C 
Sbjct: 133 MVARGRG-TVINVSSTSGFQAVPYMTVYGASKAFVLSFS--IGLWAEYRRRGVRVLALCP 189

Query: 585 GATDTALLTDEKLGT 629
           G TDT     E LGT
Sbjct: 190 GPTDTEFF--EVLGT 202


>UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Acidobacteria bacterium (strain Ellin345)
          Length = 271

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 57/199 (28%), Positives = 93/199 (46%), Gaps = 4/199 (2%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M  +   KV  +TG A GIGE+  R +   G   +AILD  E+AG    A + + +G + 
Sbjct: 1   MKIDLSGKVAVVTGGAMGIGEACARKIALAGAS-VAILDPNEDAGTKTAAAIRA-HGGEC 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383
           KF+R DV+  +     +  V+ +   ID++++NA +     G      E +   +I   L
Sbjct: 59  KFFRCDVSKSKDVEQAVGDVITKHSQIDILVSNAGI--QYYGDVITTPEDDWDRVIGVNL 116

Query: 384 KAIEIMGK----HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
           K   ++ K    H    GG ++ + SV + T       Y  +K AVL  +  +     ++
Sbjct: 117 KGCFLISKFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMAL--DYA 174

Query: 552 KTGVRVLTVCLGATDTALL 608
             G+RV  VC G  DT +L
Sbjct: 175 HKGIRVNCVCPGTIDTPML 193


>UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4;
           Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase
           - Clostridium perfringens (strain SM101 / Type A)
          Length = 253

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 65/210 (30%), Positives = 99/210 (47%), Gaps = 10/210 (4%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           +S   K+KVV +TG   GIG + V+  LD G K +A+    +E       ELN    N  
Sbjct: 4   LSKSIKNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYD 62

Query: 204 KF-YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNV 359
              +  ++ D      +++ V+++ G ID++INNA  ++D+  IY        K I++NV
Sbjct: 63  AIGFYPNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINV 121

Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539
            A+   T    EIM      K G ++N SSV +L        Y  +K AV   +  + R 
Sbjct: 122 KAIFNCTKAVSEIM---KNKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLAR- 177

Query: 540 EHFSKTGVRVLTVCLG--ATDTALLTDEKL 623
               + G+RV  V  G  ATD     D+KL
Sbjct: 178 -ELGRDGIRVNAVAPGIIATDMVAALDKKL 206


>UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5;
           Proteobacteria|Rep: Short chain dehydrogenase -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 278

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 64/205 (31%), Positives = 92/205 (44%), Gaps = 7/205 (3%)
 Frame = +3

Query: 15  TLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG 194
           T + S+E     V ITGA TGIG +       EG + +A+    EEAG +L AEL +  G
Sbjct: 23  TNQRSNEMNTPTVLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LG 80

Query: 195 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEV 353
           N+ +F  +DV  E     ++   V   G IDV +NNA        ++  S   Y +   V
Sbjct: 81  NEAEFLLADVRFEADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGV 140

Query: 354 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533
           NV   + S    + +M        G++IN+SSVA         +Y A+K AV   +    
Sbjct: 141 NVLGTMLSLKHEMRVMLAQG---SGSIINLSSVAGKVGIAGASVYVASKHAVEGLTKSAA 197

Query: 534 RPEHFSKTGVRVLTVCLGATDTALL 608
                +  GVRV  V  G   T +L
Sbjct: 198 L--EGAAAGVRVNAVAPGPVATEML 220


>UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Polaribacter dokdonensis MED152|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaribacter dokdonensis
           MED152
          Length = 259

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 61/193 (31%), Positives = 96/193 (49%), Gaps = 8/193 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K   ITGA++G+G+   +I    G   + I+  +++  Q L+ +L  K+G        D+
Sbjct: 3   KTALITGASSGLGKEFAKIHAKNG-GDLVIVARSKDKLQKLKEKLEKKHGVHVSIIEKDL 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG-IYKKA-------IEVNVTALITST 380
           T+      + N V   +  ID +INNA      IG  +++A       I++N+ AL   T
Sbjct: 62  TEPNAAQEVYNFVKFSKIEIDYLINNAGF--GGIGKFHERAWAQDLAMIQLNIIALTDLT 119

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
            K +    + + GK   ++NVSS A+L    +  +YFATK+ V  FSN I    H +K  
Sbjct: 120 RKFLPDFVERNQGK---ILNVSSTASLMAGPMQAVYFATKAFVTSFSNAIAEELHDTK-- 174

Query: 561 VRVLTVCLGATDT 599
           V V T+  GAT T
Sbjct: 175 VTVTTLMPGATKT 187


>UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase family
           protein; n=1; Gramella forsetii KT0803|Rep: Short-chain
           dehydrogenase/reductase family protein - Gramella
           forsetii (strain KT0803)
          Length = 271

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 52/202 (25%), Positives = 103/202 (50%), Gaps = 6/202 (2%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           ++++K V ITG A+GIG  + +  +++G   + ILDI + A Q ++ +L +       F 
Sbjct: 3   KFRNKTVLITGGASGIGLLLTKFSIEKGASALIILDIDKPALQQVELQLKTNICQILSF- 61

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALIT 374
            +D+++E      +  +  +   +D++INNA ++        ++    + ++VN  A + 
Sbjct: 62  ETDLSNEIQIENAVKKITAQNLQVDILINNAGVVTGKNFSEHNLEDIDRNMQVNAIAPMK 121

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
            T   +  M K    K G ++N+SS A++  +  M +Y A+K A+  +S+ +       +
Sbjct: 122 LTKLLLPEMLKR---KSGHIVNISSAASMLSNPGMSVYCASKWAMTGWSDSLRLEMERER 178

Query: 555 TGVRVLTVCLGATDTALLTDEK 620
           TG++VLTV     DT +    K
Sbjct: 179 TGIKVLTVTPYYIDTGMFEGVK 200


>UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24;
           Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE -
           Wolinella succinogenes
          Length = 247

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 45/166 (27%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           ++  K V ITG++ GIG  + R+L + G+K              L+AE+ +K G +    
Sbjct: 2   KFSGKNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVI 60

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALIT 374
             D TDEE F+  +  ++   G +  ++NNA + ND + I      ++  IE N+T+   
Sbjct: 61  SFDATDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFI 120

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 512
            + +A++ M K    + G+V+N+SS+     +     Y A+K  ++
Sbjct: 121 GSREALKSMSKQ---RFGSVVNISSIVGERGNAGQTNYSASKGGMI 163


>UniRef50_Q1Q261 Cluster: Strongly similar to
           3-oxoacyl-[acyl-carrier protein] reductase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to 3-oxoacyl-[acyl-carrier protein] reductase -
           Candidatus Kuenenia stuttgartiensis
          Length = 239

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 51/193 (26%), Positives = 100/193 (51%), Gaps = 7/193 (3%)
 Frame = +3

Query: 51  VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           + +TG + GIG+++ ++ + EG    V H   +D  E+    L+ E +S  G+ +   ++
Sbjct: 1   MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 392
           DVTD      +++ +V++ G IDV+INNA ++ D   +   A + N  +   +T      
Sbjct: 56  DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115

Query: 393 EIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
           + + +H  G + GT+IN++S++ +T       Y A K  V+ F+  + +    +   +RV
Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSK--ELAPFCIRV 173

Query: 570 LTVCLGATDTALL 608
            TV  G  +T ++
Sbjct: 174 NTVAPGVIETDII 186


>UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
           reductase; n=1; Bacillus sp. SG-1|Rep:
           3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus
           sp. SG-1
          Length = 246

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 55/195 (28%), Positives = 97/195 (49%), Gaps = 6/195 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K+K   ITG+A GIG +  +    EG K + + D  E  G + +AE   + G  T FY+ 
Sbjct: 4   KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 380
           DV + E    +   V+++ G ID++INNA +  D++        +++ ++VN+T +   T
Sbjct: 62  DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
              +  +   + GK G +IN +S + L  +     Y A+K+AV+  +    +   F   G
Sbjct: 122 QALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAK--EFGPKG 176

Query: 561 VRVLTVCLGATDTAL 605
           + V  V  G  +T +
Sbjct: 177 INVNAVAPGVIETEM 191


>UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP
           protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 629

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 57/192 (29%), Positives = 94/192 (48%), Gaps = 17/192 (8%)
 Frame = +3

Query: 57  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQ---SLQAELNSKYGNKTKF-----Y 212
           +TG A+GIG ++   L ++GV  + + D +EE GQ   SL  E N+K+     F      
Sbjct: 11  VTGGASGIGRALCLALAEKGV-FVTVADFSEEKGQETTSLVREANAKFHQGLSFPSAIFV 69

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN---------DSIGIYKKAIEVNVTA 365
           + DVT+    L   +  +   G +D+ INNA +           D    +K  I V++ A
Sbjct: 70  KCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDLIA 129

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           ++  T  AI+ M      K G +IN+ S A L    V PIY A+K+ V+ F+  +    +
Sbjct: 130 VVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---Y 184

Query: 546 FSKTGVRVLTVC 581
           + + G+R+  +C
Sbjct: 185 YRRQGIRINVLC 196


>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=225; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
           cholerae
          Length = 244

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 60/201 (29%), Positives = 98/201 (48%), Gaps = 9/201 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGA+ GIG+++  +L + G K I     +E   Q++   L    G+  K    +V
Sbjct: 6   KVALVTGASRGIGKAIAELLAERGAKVIGTAT-SESGAQAISDYL----GDNGKGMALNV 60

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 386
           T+ E    +L A+  E GG+D+++NNA +  D++ +  K       +E N+T++   +  
Sbjct: 61  TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
            +  M K    + G +INV SV     +     Y A K+ V+ F+  + R    +  GV 
Sbjct: 121 VLRGMMKK---RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAR--EVASRGVT 175

Query: 567 VLTVCLG--ATD-TALLTDEK 620
           V TV  G   TD T  L DE+
Sbjct: 176 VNTVAPGFIETDMTKALNDEQ 196


>UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium
           japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
          Length = 248

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 58/193 (30%), Positives = 94/193 (48%), Gaps = 5/193 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITGA +GIG ++ R+   EG K + + D+A E G +L A L +  G+   F   DV
Sbjct: 7   KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 404
           TDE     ++ A V   G +D+++ NA +      I++  + V+   +I   L  + I  
Sbjct: 64  TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122

Query: 405 KHSGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
           K + G      GG ++N++S+ A         Y A K+AV+  +  +     ++  G+R 
Sbjct: 123 KFAAGIMRATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALT--YALQGIRA 180

Query: 570 LTVCLGATDTALL 608
             V  G  DT LL
Sbjct: 181 NCVSPGYVDTPLL 193


>UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase, putative; n=26; Gammaproteobacteria|Rep:
           3-oxoacyl-(Acyl carrier protein) reductase, putative -
           Idiomarina loihiensis
          Length = 254

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 15/217 (6%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           KD V+ ITG A G+G ++      +G K +A++DI  +     Q +       K   Y  
Sbjct: 4   KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 353
           D+TDEE    +   + QE  GIDV++NNA L+ D + I               ++  ++V
Sbjct: 63  DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122

Query: 354 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533
           N+T       +A   M K   GK G +IN+SSVA    +     Y ATK+ V+  +    
Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVAR-AGNMGQTNYSATKAGVVAMTVTWA 179

Query: 534 RPEHFSKTGVRVLTVCLGATDTALLTDEKLGTFDKYL 644
           R     + G+R   +  G  +T +    K    D+ L
Sbjct: 180 R--ELGRYGIRCGAIAPGFIETPMTAQMKPEAVDRAL 214


>UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1;
           Terrabacter sp. DBF63|Rep: Short-chain
           dehydrogenase/redutase - Terrabacter sp. DBF63
          Length = 252

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 7/202 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS+    KV  +TG   GIG    ++L+D G + + + D++E+AG      ++   G+  
Sbjct: 1   MSNSLDGKVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAV 57

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVT 362
            F R+DVTD      ++ A V   G +D+  NNA        L + ++  + K I VN+T
Sbjct: 58  AFVRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLT 117

Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542
            +  S +KA EI    + G GG++IN +S            Y  +K  V+  +       
Sbjct: 118 GVFIS-MKA-EIPQMLAQG-GGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAA--V 172

Query: 543 HFSKTGVRVLTVCLGATDTALL 608
            +S  G+RV  V  G   T ++
Sbjct: 173 EYSDKGIRVNAVLPGVIQTPMI 194


>UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 261

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 63/200 (31%), Positives = 93/200 (46%), Gaps = 11/200 (5%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E   KV  ITG   G G++    L + G  H+ + DI  +   +  AEL +  G+ T   
Sbjct: 14  EHAGKVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV- 71

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTA 365
             DVTDE     ++  +V+  GG+D+++NNA L + +          G  ++  EVNV  
Sbjct: 72  TCDVTDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMG 131

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           ++  TL A + M   SG  G  V+N+SS AA         Y  +K AV  F+    R   
Sbjct: 132 VVICTLAAKDAM---SGRAGAAVVNISSSAAYAN---RTAYGVSKLAVRGFTAQFAR--E 183

Query: 546 FSKTGVRVLTVCLG--ATDT 599
            +  GVRV  +  G   TDT
Sbjct: 184 LAAVGVRVNAIAPGLILTDT 203


>UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3;
           Lactobacillus reuteri|Rep: Short-chain dehydrogenase -
           Lactobacillus reuteri
          Length = 277

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 8/195 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY----GNKTK 206
           +++VV ITG ++GIG+     L  E  +  AI+ +     + LQ E+  K     G    
Sbjct: 12  RNEVVLITGGSSGIGKE----LAFEAARRGAIVVVVSRNLEKLQ-EVAKKCLILSGRPAF 66

Query: 207 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 386
            Y+ DVTD +    +L+ V  E GGIDV+IN+A L  D I + K++       + T+ L 
Sbjct: 67  AYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGL-GDFIPVVKESYSSMEKMVHTNLLA 125

Query: 387 AIEI---MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
            + I   + K    +G G +IN+ S+A    +    +Y ATK+ V+QF N + R E  + 
Sbjct: 126 LMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKAGVIQFDNVL-RME-VAD 183

Query: 555 TGVRVLTVCLGATDT 599
            GV+VLTV  G  DT
Sbjct: 184 YGVQVLTVNPGPIDT 198


>UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=16; Pseudomonas|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Pseudomonas aeruginosa PA7
          Length = 266

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 55/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +   ITGA++GIG ++   L   G + + ++    +A +S+  EL  ++G +  F   D+
Sbjct: 3   RYALITGASSGIGLALAEALARRG-RALILVARQRDALESIAYELAQRFGVEVLFRTCDL 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386
            +     G+L+ + Q +  ID+++NNA +      ++      ++ IE+N+ AL     +
Sbjct: 62  AEPLQLSGLLHELEQGERQIDLLVNNAGIGSAGPFVDQEWAREQELIELNILALA----R 117

Query: 387 AIEIMGKHSGGKGG-TVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
               +G     +GG  ++NV+SVAA      M  Y+A+K+ VL FS   G  E      V
Sbjct: 118 LCHALGTRMAAQGGGQILNVASVAAFQPGAWMSNYYASKAYVLHFSE--GLREELKARAV 175

Query: 564 RVLTVCLGATDTALLTD 614
           +V  +C G T TA   +
Sbjct: 176 KVSVLCPGPTRTAFFRE 192


>UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 266

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           ++   +TGAA GIGE + R    EG   + + D  +E G ++  +L    G + +F R D
Sbjct: 8   NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 392
           V+  E  +G ++  V+  G +D+++NNA      + I KK  E    AL   + +T  A+
Sbjct: 66  VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125

Query: 393 EIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
           E    H   KG G VIN++S+  +        Y   K AV  +S    R   ++  G+ V
Sbjct: 126 ERALPHMKAKGWGRVINMASLNGVNAHMGSADYNVAKEAVRAYSRTAAR--EWAPYGICV 183

Query: 570 LTVCLGATDTA 602
             +C  A   A
Sbjct: 184 NVICPAAVSAA 194


>UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Enterobacter sp. 638|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Enterobacter sp.
           638
          Length = 242

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 60/200 (30%), Positives = 100/200 (50%), Gaps = 6/200 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M+ E K +V  +TGA++GIGE++ R L   G++ + +L    E    L +EL    G+  
Sbjct: 1   MNIEKKKRVAVVTGASSGIGEALARELAGNGIQ-VVLLARRFERIDVLASEL----GHGA 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365
              ++DVTD E  +   N V Q  GG+D++INNA +M      +  +  +++ +E N+  
Sbjct: 56  IAIKADVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLG 115

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
            +T T    E+         G ++N+SSVA         +Y ATK  +  +S  + R E 
Sbjct: 116 AMTVT----EVFLPQLRRNKGDLVNISSVAGRVAPSGFAVYAATKWGINGWSEAL-RVE- 169

Query: 546 FSKTGVRVLTVCLGATDTAL 605
             +  +RV+ +  GA  T L
Sbjct: 170 -LQPDIRVMVIEPGAIATEL 188


>UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative
           3-oxoacyl-[acyl-carrier protein] reductase -
           Arthrobacter aurescens (strain TC1)
          Length = 261

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K V +TGA +G+G +V +  L EG   I + D++E++    + + NS    +     +DV
Sbjct: 9   KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386
            D +    I+N  V+E G +DV++NNA +         S  +++  ++VNV  L  +T  
Sbjct: 67  GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A+     H     G ++N +SV+ +   +    Y A+K AV+ F+  +     +++ GVR
Sbjct: 127 AL----PHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVA--VDYAQRGVR 180

Query: 567 VLTVCLGATDTALL 608
              V  G   T LL
Sbjct: 181 CNAVAPGPVLTPLL 194


>UniRef50_Q2UEK6 Cluster: Dehydrogenases with different
           specificities; n=2; Aspergillus|Rep: Dehydrogenases with
           different specificities - Aspergillus oryzae
          Length = 261

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 56/203 (27%), Positives = 97/203 (47%), Gaps = 9/203 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGA +GIG      L + G  ++ + +  E  G+   A+++++ G++  F  +DV
Sbjct: 13  KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383
           +  E    ++ A ++  G +D+ +NNAAL  D+  I       ++K I VN+   +   L
Sbjct: 72  SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
           K  E+      G GG++IN+SS         M  Y A K  +   +          + G+
Sbjct: 131 K-WELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVEN--GRHGI 187

Query: 564 RVLTVCLG--ATDTALLTDEKLG 626
           RV  +  G  ATD  + T ++LG
Sbjct: 188 RVNALAPGGVATDLTMATMQELG 210


>UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16;
           Mycobacterium|Rep: Probable oxidoreductase ephD -
           Mycobacterium bovis
          Length = 592

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 6/195 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           D +V +TGA +GIG         EG + I I DI E   +   AE+ ++ G     Y  D
Sbjct: 324 DTLVSVTGAGSGIGRETALAFAREGAE-IVISDIDEATVKDTAAEIAAR-GGIAYPYVLD 381

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 383
           V+D E        V  E G  D+V+NNA +      ++     + + + VN+  ++    
Sbjct: 382 VSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCR 441

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
              + + +   G GG ++NVSS+AA      +  Y  +K+A   FS+C+ R E     GV
Sbjct: 442 AFGQRLVER--GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL-RAE-LDAAGV 497

Query: 564 RVLTVCLGATDTALL 608
            + T+C G  DT ++
Sbjct: 498 GLTTICPGVIDTNIV 512


>UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus
           thuringiensis
          Length = 247

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 50/196 (25%), Positives = 98/196 (50%), Gaps = 6/196 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TG A GIG+++   L  EG K +   + ++EA ++L  EL  K G+     ++DV
Sbjct: 7   KVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEAAENLVNEL-GKEGHDVYAVQADV 65

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386
           +  E    ++   V   G +D+++NNA +  D      +   +++ I+VN++++  +T  
Sbjct: 66  SKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSVFNTTSA 125

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
            +  +   +  + G +I++SS+           Y A K+ +L F+  +      +KT V 
Sbjct: 126 VLPYI---TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL--ELAKTNVT 180

Query: 567 VLTVCLGATDTALLTD 614
           V  +C G  DT ++ +
Sbjct: 181 VNAICPGFIDTEMVAE 196


>UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3;
           Proteobacteria|Rep: P-cumic alcohol dehydrogenase -
           Pseudomonas putida
          Length = 252

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 61/194 (31%), Positives = 94/194 (48%), Gaps = 9/194 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           KDKV  +TGAATGIG ++VR  L EG K + I D+  +  ++  AEL     +      +
Sbjct: 4   KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 371
           DV+D +    +  A +   G IDV++NNA +         +SI +  + K   VNV    
Sbjct: 58  DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
              L A  +      G GG +IN++SV A   +  M  Y ++K AV   +  + R    +
Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATT 174

Query: 552 KTGVRVLTVCLGAT 593
           K G+ V ++  G T
Sbjct: 175 KAGISVNSISPGYT 188


>UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1;
           Bacillus sp. SG-1|Rep: Putative uncharacterized protein
           - Bacillus sp. SG-1
          Length = 260

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 61/202 (30%), Positives = 95/202 (47%), Gaps = 7/202 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K+KVV ITGA++G+G    +         + +   +E+   +L  EL  K+G K      
Sbjct: 2   KNKVVVITGASSGLGVEFAKQFAGRSYD-LVLTARSEDKLNNLAKELEGKHGIKAHVIPI 60

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGIYKKA--IEVNVTALITST 380
           D++       +   VV      +++INNA        +   I K+   IEVN+TAL   T
Sbjct: 61  DLSQHGSAKTLHEKVVSLGLTTEILINNAGFGLFGEFEDTDIQKEVDMIEVNITALTELT 120

Query: 381 LKAIEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
               +  GK    G  G ++NV+SVAA     +M +Y+ATK+ VL  S  +     +   
Sbjct: 121 ----KYFGKEMVVGNTGKILNVASVAAFQPGPLMAVYYATKAYVLSLSEALS--NEWKDK 174

Query: 558 GVRVLTVCLGATDTALLTDEKL 623
           GV+V  +C GAT+T      +L
Sbjct: 175 GVKVSVLCPGATETGFSNSAEL 196


>UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=8; root|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Pseudomonas paucimobilis (Sphingomonas paucimobilis)
          Length = 250

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K + +TG  +GIG + V +L+  G  ++ + DI +EAG+++ A      G K  ++R D+
Sbjct: 7   KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVVATS----GGKAAYFRCDI 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 383
             EE    ++   +   GG+D   NNAA       L   S+  +++++++NVT   T   
Sbjct: 62  AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
              +I+     G  G+++N +S A +    +   Y   K AV+  +        + K G+
Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAA--ADYGKHGI 177

Query: 564 RVLTVCLGATDTALL 608
           RV  +  GA  T +L
Sbjct: 178 RVNALVPGAVRTPML 192


>UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Burkholderiaceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 252

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 51/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           +KV  +TGAA+G+G +   +L  EG + + + DI E+AG++L  E+    G+   F R D
Sbjct: 6   NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383
           + DE  +   + + +   G +DV++NNAA+       + S+  +++ +  N         
Sbjct: 61  IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            AI  M        G+++ +SSVAAL    +M  Y  +K AV   +  +    H  ++G 
Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVA--VHCKRSGY 176

Query: 564 RV 569
           R+
Sbjct: 177 RI 178


>UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain
           dehydrogenase/reductase SDR - Rhodopseudomonas palustris
           (strain BisB5)
          Length = 263

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 52/195 (26%), Positives = 88/195 (45%), Gaps = 7/195 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +VV +TG A+GIG +       +G   + + DI +  G     E   + G++ ++ R+DV
Sbjct: 21  RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383
           TDE     ++   V   G +DV  NNA +   S  I       ++  I VN+  +  S  
Sbjct: 79  TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
             + +    S G  G ++N +SV  L        Y A K  V+  + C      + ++G+
Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAAL--EYGRSGI 193

Query: 564 RVLTVCLGATDTALL 608
           R+  VC G  +T L+
Sbjct: 194 RINAVCPGYIETPLV 208


>UniRef50_Q13H99 Cluster: Putative short-chain
           dehydrogenase/reductase; n=3; Proteobacteria|Rep:
           Putative short-chain dehydrogenase/reductase -
           Burkholderia xenovorans (strain LB400)
          Length = 274

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 54/201 (26%), Positives = 100/201 (49%), Gaps = 12/201 (5%)
 Frame = +3

Query: 21  KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNK 200
           K   + ++KV  +TGA  G+G +  R L   G + +A++DI  EA  ++ A++    G +
Sbjct: 5   KAGGKLENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GER 59

Query: 201 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKA 344
               R+DV+ E     +++AV++  G ID++ NNAA+++D            S+ ++ +A
Sbjct: 60  AMSVRTDVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRA 119

Query: 345 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 524
           + VN+   +     AI  M +   G GG++I+ SS         M  Y A+K+ +   S 
Sbjct: 120 MAVNLRGAMLCCKHAIPAMLR---GGGGSIIHSSSGFGAQGDFTMSAYAASKAGLAMLSK 176

Query: 525 CIGRPEHFSKTGVRVLTVCLG 587
            +     + K  +R  T+ +G
Sbjct: 177 SVA--AQYGKERIRSNTIQIG 195


>UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Roseiflexus sp. RS-1
          Length = 246

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 57/196 (29%), Positives = 94/196 (47%), Gaps = 5/196 (2%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K KV  +TGA  GIG++       EG  H+A++DI     ++  AE+ ++   +    ++
Sbjct: 4   KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDINMAGAEATVAEI-TRLDGRALAVQA 61

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 398
           DV+       ++  V+   G IDV++NNA +  D+  +  K  E    A+I   LK + +
Sbjct: 62  DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119

Query: 399 MGK----HSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
             +    H   +G G++INVSS+  L  +     Y ATK  V+  +    R      +GV
Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR--ELGPSGV 177

Query: 564 RVLTVCLGATDTALLT 611
           RV  V  G   T ++T
Sbjct: 178 RVNAVTPGFIATEMIT 193


>UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;
           n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
           FadB2x - Pseudomonas stutzeri (strain A1501)
          Length = 258

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 67/219 (30%), Positives = 100/219 (45%), Gaps = 17/219 (7%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           +DKVV ITG A+G+G +    L  E    IAI D+  EAG+   A L ++   +  F  +
Sbjct: 4   QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 365
           DV+ EE     ++AV+   G I V IN AA+               +  + +A  +N+  
Sbjct: 61  DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120

Query: 366 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 536
           +     K  E M K+   +G + G VINVSS AA         Y ATK+ V+  +    R
Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAAR 180

Query: 537 PEHFSKTGVRVLTVCLG---ATDTALLTDEKLGTFDKYL 644
                  GVRV  +  G    T  A L ++ LG+  + +
Sbjct: 181 --ELGAIGVRVNAIAPGLFLTTMVAALDEKVLGSLKEQM 217


>UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase,
           putative glucose-1-dehydrogenase; n=1; Pyrococcus
           abyssi|Rep: Short-chain alcohol dehydrogenase, putative
           glucose-1-dehydrogenase - Pyrococcus abyssi
          Length = 240

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 57/202 (28%), Positives = 98/202 (48%), Gaps = 7/202 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           E K KV  ITGA+ GIG ++   L   GV  +      EE  +  + EL  +YG +T   
Sbjct: 2   ELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLV 60

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALI 371
           ++DV++ E    ++  V+ + G ID++INNA ++    D + +    + + I VN+    
Sbjct: 61  KADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAF 120

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
             T + +  M      K G ++N++S+A      V P Y A+K  ++  +  + R  H +
Sbjct: 121 IVTQEVLRYM------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR--HLA 172

Query: 552 KTGVRVLTVCLGATDTALLTDE 617
              + V  V  G  DT +L+ E
Sbjct: 173 -PNILVNAVAPGPVDTDMLSSE 193


>UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60;
           Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter
           sphaeroides (Rhodopseudomonas sphaeroides)
          Length = 256

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 53/188 (28%), Positives = 96/188 (51%), Gaps = 4/188 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K   ITG+A GIG +     + EG + +AI DI  EA ++  AE+    G        DV
Sbjct: 6   KTALITGSARGIGRAFAEAYVREGAR-VAIADINLEAARATAAEI----GPAACAIALDV 60

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIEI 398
           TD+      +  ++   G ID+++NNAAL + +  + I +++ +      ++ TL  ++ 
Sbjct: 61  TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120

Query: 399 MGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
           + +   +GG+GG +IN++S A      ++ +Y ATK+AV+  +   G   +  + G+ V 
Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLIRHGINVN 178

Query: 573 TVCLGATD 596
            +  G  D
Sbjct: 179 AIAPGVVD 186


>UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
           16129)
          Length = 256

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 58/200 (29%), Positives = 92/200 (46%), Gaps = 10/200 (5%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           +D+V  ITGAA+G G +  ++   EG K +A  DI E   Q    E+    G  T   + 
Sbjct: 4   EDRVAVITGAASGQGRAAAKLFASEGAKVVA-ADIDEGGAQRTVEEIKEAGGEATA-VKV 61

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV-----TALITSTL 383
           DV+ E     ++ +     G +DV+ NNA +   + G  K A  V        A++   L
Sbjct: 62  DVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINL 121

Query: 384 KAIEIMGKHS----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 548
           K + +  KH+      +G G++IN +S+ AL        Y A K  V+ FS  +     +
Sbjct: 122 KGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLA--VEW 179

Query: 549 SKTGVRVLTVCLGATDTALL 608
              G+RV  +C G  DT ++
Sbjct: 180 GPRGIRVNCICPGGVDTPMI 199


>UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivorax
           borkumensis SK2|Rep: Oxidoreductase, putative -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 581

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 7/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K V ITGA +GIG          G   +   DI  E   +    + ++ G +    + DV
Sbjct: 315 KRVIITGAGSGIGRETALAFARRGAL-VVCTDINSEEAAATARTITAE-GGEALSRKCDV 372

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALIT-STL 383
           ++      +   V +E G  D+V+NNA      +L++ S+  +++ + VN+  +I  S L
Sbjct: 373 SNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKDWQQVLGVNLWGVIHGSRL 432

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            A +++ +   G+ G ++N++S AA   S ++P Y  +KSAVL FS C+ R E   +  +
Sbjct: 433 FARQMIDQ---GRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMFSECL-RAE-MDEHNI 487

Query: 564 RVLTVCLGATDTAL 605
            V  +C G  +T +
Sbjct: 488 GVSAICPGIINTPI 501


>UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Xanthobacter autotrophicus Py2|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Xanthobacter sp. (strain Py2)
          Length = 261

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 8/201 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           KDK + ITGAA GIG ++ + L  +G + I + D++E A +++  E+ +  G        
Sbjct: 5   KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 380
           DV        +L+  V   G +DV+ NNA +      ++ +   ++   +VN   ++   
Sbjct: 63  DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
            +AI+   K  GG GG ++N +S+AA      +  Y A+K AV+  +    R   F K  
Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARA--FGKDQ 178

Query: 561 VRVLTVCLG--ATDTALLTDE 617
           + V   C G  ATD   + D+
Sbjct: 179 ITVNAFCPGVVATDMWKIIDK 199


>UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Marinomonas sp. MED121|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MED121
          Length = 255

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 58/207 (28%), Positives = 101/207 (48%), Gaps = 7/207 (3%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           +KD+VV ITGA+ G+G+   +    +G K +A+ D+   A   L  EL  + G +     
Sbjct: 4   FKDQVVLITGASGGLGKEAAKQFAQQGAK-LALCDLNVAALNDLGTEL-IEQGYEVFSQP 61

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALIT 374
            DV++E+     ++      G +DV INNA        L +     +++ +++NV  +  
Sbjct: 62  CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
                I  M K     GG + N+SSVA ++ +  M  Y A+K AV+  +  +     + +
Sbjct: 122 CMKYQIPHMIKQG---GGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVA--HEYGR 176

Query: 555 TGVRVLTVCLGATDTALLTDEKLGTFD 635
            G+RV +VC   T T ++ ++ L T D
Sbjct: 177 AGIRVNSVCPYITMTDMV-EQHLKTLD 202


>UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1; Marinomonas
           sp. MED121|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Marinomonas sp.
           MED121
          Length = 259

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 58/185 (31%), Positives = 90/185 (48%), Gaps = 6/185 (3%)
 Frame = +3

Query: 51  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230
           V +TG A+GIGE++V+ L  +G   ++  DI EEAG+ L   LNS +G K  F   D+TD
Sbjct: 20  VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77

Query: 231 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 392
            E     + A ++  G I  ++NNAA      L   S   + + + VN+     +  K  
Sbjct: 78  IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137

Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
            +M +     GG++IN+SS + +      P Y   K+ +   +  + R      T VRV 
Sbjct: 138 PLMAE---AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALAR--ELGPTKVRVN 192

Query: 573 TVCLG 587
           TV  G
Sbjct: 193 TVLPG 197


>UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain
           dehydrogenase/reductase SDR - Verminephrobacter eiseniae
           (strain EF01-2)
          Length = 265

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 55/197 (27%), Positives = 93/197 (47%), Gaps = 6/197 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITGA +GIG +   +   EG + I + D+  E GQ+    +    G +  F ++DV
Sbjct: 16  KVALITGAGSGIGRATALLFATEGAQ-IVVCDLDPEGGQATVRAIEQA-GAQALFVQADV 73

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386
                    +   ++    +DV+ NNA +      ++ S   +   + VNV ++   + +
Sbjct: 74  AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A+ +M +  GG   ++IN  S   L        Y A K AV+  +  +   +H  +  +R
Sbjct: 134 AVPVMAEQGGG---SIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMAL-DHGPQR-IR 188

Query: 567 VLTVCLGATDTALLTDE 617
           V +VC G TDTA+L DE
Sbjct: 189 VNSVCPGDTDTAMLRDE 205


>UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=18; Bacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Arthrobacter sp.
           (strain FB24)
          Length = 263

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 60/208 (28%), Positives = 98/208 (47%), Gaps = 18/208 (8%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTK-FYR 215
           K  V  ITG A+G+G +  R L D G   + ++D+    G++  AELN+  G  T  F  
Sbjct: 4   KGTVALITGGASGLGAATARRLFDAGAS-VVLVDLPSSRGEAFAAELNAASGAGTAVFVP 62

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS----------IGIYKKAIEVN--- 356
           +DVT EE     + A V   G + +V+N A +              +  + + I++N   
Sbjct: 63  ADVTSEEQVQAAVAAAVA-LGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINLVG 121

Query: 357 ---VTALITSTLKAIEIMGKHSGG-KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 524
              V  L  + + A E +    GG + G +IN +SVAA       P Y A+K AV   + 
Sbjct: 122 TFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMTL 181

Query: 525 CIGRPEHFSKTGVRVLTVCLGATDTALL 608
            I R    +++ +RV+T+  G  +T ++
Sbjct: 182 PIAR--ELARSLIRVVTIAPGIFETPMM 207


>UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 292

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 54/209 (25%), Positives = 97/209 (46%), Gaps = 6/209 (2%)
 Frame = +3

Query: 9   YGTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSK 188
           Y +   +   + KV F+TG A+GIG  +V   + EG K +AI+D+ +    +   ELN +
Sbjct: 24  YYSTNQNGRMEKKVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQR 82

Query: 189 YGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIE 350
           +   T     DV++EE     +   V+  GG+DV+++NA L +        +  ++K + 
Sbjct: 83  FPGSTISVECDVSNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMA 142

Query: 351 VNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530
           V++      T  A++   K    +GGT++ + SV +   S     Y   K  +     C 
Sbjct: 143 VHLDGAFLCTKYAMQEF-KKDIKRGGTILYMGSVHSKYASEYKIPYVTAKHGLEGL--CR 199

Query: 531 GRPEHFSKTGVRVLTVCLGATDTALLTDE 617
           G     +K  +R   +C G   T L+ ++
Sbjct: 200 GVAREGAKHNIRANLICPGFVLTPLVKNQ 228


>UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80593 protein -
           Strongylocentrotus purpuratus
          Length = 258

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 7/186 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           + V ITG+A G+G  + +     G + + +LDI  E  + L  EL SK G     Y  D+
Sbjct: 63  RTVLITGSANGLGRLLAQEFARRGAQ-LVLLDIDIEGNKLLAEELCSK-GRSAHAYYCDL 120

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 386
           + +     ++  + ++ G +D++INNAA ++       S    +K  EVN  A I  T  
Sbjct: 121 SRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKA 180

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG-RPEHFSKTGV 563
            +  M      K G V+N++S+A     + +  Y A+KSA++ F+  +G   +    TGV
Sbjct: 181 LLPDMLNR---KQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGV 237

Query: 564 RVLTVC 581
            +  VC
Sbjct: 238 HLSLVC 243


>UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; Leptospira|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Leptospira interrogans
          Length = 247

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K+K V +TG+  GIG         EG K+     I    G S Q  +    G+  K + +
Sbjct: 8   KNKTVLVTGSTRGIGRYFA-----EGFKNAGA--IVYGTGSS-QESIKKFDGSGIKGFAA 59

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 392
           D+   +    I+ ++V+E G +DV++NNA + ++    + K  E+   +    T   +A 
Sbjct: 60  DIRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRAC 119

Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
               K    KGG +IN++S+  +  + +  +Y  TK AV+  +  +     +  +G RV 
Sbjct: 120 TAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALA--VEWIGSGYRVN 177

Query: 573 TVCLGATDT 599
            +C G  DT
Sbjct: 178 AICPGFIDT 186


>UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase,
           putative; n=25; Alphaproteobacteria|Rep:
           20-beta-hydroxysteroid dehydrogenase, putative -
           Silicibacter pomeroyi
          Length = 250

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 59/202 (29%), Positives = 94/202 (46%), Gaps = 8/202 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K K V ITGA+ GIG    R+    G  ++ +L  + EA  +  AE+    G++      
Sbjct: 5   KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 374
           DV D     G +NA V   GG+DV+INNA ++        +D +G +  AI++N+  +  
Sbjct: 60  DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 554
               A+ +M K     GGT++ VSS AA         Y A+K+     + C+   E    
Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAAHNPVEAWSHYCASKAGAAMLTACLHLEE--GH 173

Query: 555 TGVRVLTVCLGATDTALLTDEK 620
            G+R + +  G   T +  + K
Sbjct: 174 HGIRAMGLSPGTVATQMQREIK 195


>UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2;
           Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases
           - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
           NCIB 8253 / DSM158)
          Length = 247

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 59/201 (29%), Positives = 95/201 (47%), Gaps = 6/201 (2%)
 Frame = +3

Query: 51  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230
           + ITGA +GIG    R    EG   +A++D  E A Q    E           +  DVTD
Sbjct: 10  IVITGAGSGIGRESARQFAREGAT-LALIDRDEAAAQVTADETGGHV------FALDVTD 62

Query: 231 EEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLKAI 392
           E     ++    +  GGID ++N+A ++     D IG+  +++ ++VN+T        A+
Sbjct: 63  EAAVETVVGRAAEALGGIDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQAAL 122

Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
             + K        ++N++S  AL  S     Y A+K+AV+ FS  I +        VRV 
Sbjct: 123 PWLRKE---PKAAIVNIASAQALLPSLTGSAYAASKAAVMMFSKSIAKE---LAPAVRVN 176

Query: 573 TVCLGATDTALLTDEKLGTFD 635
            +C GAT+T  +TD+ +   D
Sbjct: 177 IICPGATETP-MTDQGVAPDD 196


>UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 251

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 59/203 (29%), Positives = 96/203 (47%), Gaps = 6/203 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K   +TGA +GIG ++      EG + +A+ D+ E A + + AE+    G      R+DV
Sbjct: 7   KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 386
           T  E   G++    +  GG++V++NNA +         S   +++ + VN+         
Sbjct: 62  TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           AI  + + SG  GG VIN+SS+AAL        Y A K  +L  +   G  +H  + GVR
Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAALVGLKDRAAYSAAKGGILALTRA-GAIDHIHE-GVR 176

Query: 567 VLTVCLGATDTALLTDEKLGTFD 635
           V  +  G  +T  ++    G  D
Sbjct: 177 VNCIAPGTVETPWISRITAGYAD 199


>UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1;
           Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: Putative uncharacterized protein - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 247

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 63/201 (31%), Positives = 99/201 (49%), Gaps = 9/201 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV+ ITGA++GIGE++ +     G K I +    EE  + ++A++ +  G + ++  +DV
Sbjct: 5   KVIVITGASSGIGEAIAKKQAAAGDK-IVLGARREENLKQIKADIEAG-GGQAEYLVTDV 62

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386
           TD E    +    +   G IDV INNA LM  S+ I      + + I+VN+   +     
Sbjct: 63  TDVEQVKALAQKAMDAYGRIDVWINNAGLMPHSLLIDARIDDWNRMIDVNLKGTLYGIAA 122

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A  I    + G     IN+ SVA+L       +Y ATK AV   S  +   E  +   VR
Sbjct: 123 AQHIFHDQNTGH---FINLGSVASLYSHAGGAVYSATKWAVKAISESLREEEAQAGKNVR 179

Query: 567 VLTVCLGATDTAL---LTDEK 620
           V ++  GA ++ L   +TD K
Sbjct: 180 VTSLYPGAIESELVANMTDSK 200


>UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Parvibaculum
           lavamentivorans DS-1
          Length = 287

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 56/195 (28%), Positives = 95/195 (48%), Gaps = 8/195 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITG  +GIG   V + L EG K +A  D+ +  G++++ EL    G    + R++V
Sbjct: 7   KVAIITGGTSGIGRGTVDLFLKEGAKVVAA-DLQDHKGEAMEREL----GENFSYCRANV 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN-----VTALITSTLKA 389
             E+    +++  V++ G +D++ NNA      +G   + I++N     V  L+   +  
Sbjct: 62  AHEDEVKNLVDHTVKKFGKLDILFNNAGY--GGVGGELQEIDMNGFDETVGVLLKGVVLG 119

Query: 390 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC--IGRPEHFSKTG 560
            +    H    K G++I+ +SVA L   +   +Y A K+AV  FS C  +    HF    
Sbjct: 120 YKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAALELAPHF---- 175

Query: 561 VRVLTVCLGATDTAL 605
           VR   +C G   T++
Sbjct: 176 VRSNAICPGGIATSI 190


>UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Sphingomonadaceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 261

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 53/201 (26%), Positives = 100/201 (49%), Gaps = 8/201 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS +   KV  +TG + GIG +  R+L   G   + I    E+  ++ +AE+ +K G K 
Sbjct: 1   MSQDMTGKVAIVTGGSDGIGLATARLLAARGAT-VVICARREDKLEAARAEI-AKVG-KV 57

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA 365
           +  + DV+DE  F  ++  V    G +D+++NNA  ++ +      +  ++K   VN  A
Sbjct: 58  EAVKLDVSDEAAFTALVEDVAARHGRLDMLVNNAMSVHYAPIAKLRLDHWRKDFAVNADA 117

Query: 366 LITSTLKAIEIMG--KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539
           +   T  A+++M   +  G + G ++N++S   +  +  M  Y A+K+A++ F+      
Sbjct: 118 VFVGTKAAMKVMAAQEQRGRQRGAIVNIASTCGIRAAPNMASYSASKAAMVHFTAAAAM- 176

Query: 540 EHFSKTGVRVLTVCLGATDTA 602
              +  G+RV  +  G   TA
Sbjct: 177 -EGAPLGIRVNAIVPGQVMTA 196


>UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium gilvum
           PYR-GCK
          Length = 543

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 59/193 (30%), Positives = 87/193 (45%), Gaps = 4/193 (2%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           D +V +TGAA+GIG +        G   + I D+   AG    A L +  G     Y  D
Sbjct: 274 DTLVAVTGAASGIGRATALAFAHHGAD-VVISDV-NAAGLDETARLVTSAGVHAYPYTVD 331

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT--STLKAIE 395
           V D          V  E G  DVV+NNA + +    +   A E +    I     +    
Sbjct: 332 VADAAAVEAFAEQVCAEHGVPDVVVNNAGVGHAGFFLDTPAEEFDRVLDINFGGVVNGCR 391

Query: 396 IMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 569
             GK     G GG ++NV+S+A+ T  +VM  Y  +K+AV  FS+C+ R E     G+ +
Sbjct: 392 SFGKRLADRGVGGHIVNVASMASYTPVNVMNAYCTSKAAVFMFSDCL-RAE-LDSFGIGL 449

Query: 570 LTVCLGATDTALL 608
            T+C G   T ++
Sbjct: 450 TTICPGFISTNIV 462


>UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like
           protein; n=1; Reinekea sp. MED297|Rep: Short-chain
           alcohol dehydrogenase-like protein - Reinekea sp. MED297
          Length = 672

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 51/170 (30%), Positives = 90/170 (52%), Gaps = 9/170 (5%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELN-SKYGNKTKFYRSD 221
           KVV ITG ++GIG++    L   G     ++  A +A +  +A L+    G     +++D
Sbjct: 385 KVVLITGGSSGIGKATAMRLSKAGA---TVIICARDAEKLRRAHLDIESTGGTVVSHQAD 441

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVNVTALITS 377
           +T  +    +   + +E  G+D++INNA      ++M   D +  +++ IE+N  A +  
Sbjct: 442 ITQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVAI 501

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 527
           TLKA+ +M +    + G VIN+SS+  L+ S     Y A+K+A+  FS C
Sbjct: 502 TLKALPMMDRR---REGHVINISSIGVLSNSPRFSAYVASKAALEAFSRC 548


>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Bacillus coagulans 36D1|Rep: Short-chain
           dehydrogenase/reductase SDR - Bacillus coagulans 36D1
          Length = 262

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 52/199 (26%), Positives = 93/199 (46%), Gaps = 7/199 (3%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           ++  KV  +TG   GIG     + L  G  ++ + D+++E G+    ++    G +  F 
Sbjct: 5   DFTGKVAIVTGGGGGIGREAC-LKLAAGGANVVVADLSDELGEETAGKIREN-GGEAIFV 62

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALI 371
           R+DV+  +     +   +   G ID+++NNA        L++    ++ K + +NV  + 
Sbjct: 63  RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
                 +  M      K GT++N +SVA L  +  M  Y A+K AV+  +   G     +
Sbjct: 123 LGMKYVLPHMISQ---KSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAA 177

Query: 552 KTGVRVLTVCLGATDTALL 608
            +GVRV  VC G  DT ++
Sbjct: 178 PSGVRVNAVCPGVVDTEMM 196


>UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 286

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 59/207 (28%), Positives = 103/207 (49%), Gaps = 11/207 (5%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 227
           V  +TGAA GIG +  + L  +G++ +A+LD+  +A Q+  AEL S +         DVT
Sbjct: 21  VAIVTGAADGIGWATAQRLAADGLR-VALLDLRADAAQARAAELGSIHLG----LGCDVT 75

Query: 228 DEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNV--TALITST 380
            EE     + AV++  G ID ++NNA +          S+  + + + V++  T L++  
Sbjct: 76  SEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLRGTFLMSRA 135

Query: 381 LKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           +    +      G+G G ++N+ S+A+ T       Y A K+ VL  +  +     +++ 
Sbjct: 136 VARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA--SEWARA 193

Query: 558 GVRVLTVCLGATDTALLTD-EKLGTFD 635
           G+RV  V  G   TAL+ + E+ G  D
Sbjct: 194 GIRVNAVAPGYVRTALVAELERKGAID 220


>UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella pealeana ATCC
           700345
          Length = 254

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 55/191 (28%), Positives = 99/191 (51%), Gaps = 6/191 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS     KV  ITGAA G+G +  R++  EG + + + DI  E G+    E+ +  GN +
Sbjct: 1   MSGRLIGKVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNS 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365
            F   DVT E  +  ++N +  + G +++++NNAA++       +++  +++   VN  +
Sbjct: 56  LFIEHDVTKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDS 115

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           +      A+ +M K SG  GG++IN+SS +A+        Y A+K+A+   S  +     
Sbjct: 116 VFLRIHYALPLMEK-SG--GGSIINMSSSSAVFGMPHFAAYGASKAAIRGLSQSVAVYCS 172

Query: 546 FSKTGVRVLTV 578
            +K  VR  T+
Sbjct: 173 QTKNNVRCNTL 183


>UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila
           melanogaster|Rep: CG8757-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 266

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 13/216 (6%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           W +KV  ++GA+ GIG +  R L+  G+  + +    E   + L++ L+ +  ++    +
Sbjct: 18  WCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERV-EKLRSGLSLEQQSRLHAIK 76

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM-------NDSIGIYKKAIEVNVTALIT 374
            D+T E+  L   +   ++ GG+DV+++NA ++        D     +  IE N+   + 
Sbjct: 77  CDITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVY 136

Query: 375 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP------IYFATKSAVLQFSNCIGR 536
              ++   M K  G +G  VI V+SVA     ++ P      IY ATK A+   +    +
Sbjct: 137 CVRESFRSM-KRRGTEGHVVI-VNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQ 194

Query: 537 PEHFSKTGVRVLTVCLGATDTALLTDEKLGTFDKYL 644
                KT VRV TV  G  DT +L ++  G   +++
Sbjct: 195 EFQRHKTAVRVSTVSPGIVDTVILPEQIQGIIKQHM 230


>UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase, chloroplast precursor; n=80; cellular
           organisms|Rep: 3-oxoacyl-[acyl-carrier-protein]
           reductase, chloroplast precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 319

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 7/187 (3%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQ-AELNSKYGNKTKFYRSDV 224
           VV ITGA+ GIG+++   L   G K   +++ A  A ++ + A+   +YG +   +  DV
Sbjct: 78  VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386
           +       ++   + + G IDVV+NNA +  D++ I      + + I +N+T +   T  
Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A++IM K    K G +IN+SSV  L  +     Y A K  V+ FS    R E  S+  + 
Sbjct: 196 AVKIMMKK---KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAR-EGASR-NIN 250

Query: 567 VLTVCLG 587
           V  VC G
Sbjct: 251 VNVVCPG 257


>UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=6;
           Clostridium|Rep: Predicted short-chain dehydrogenase -
           Clostridium acetobutylicum
          Length = 262

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 50/188 (26%), Positives = 91/188 (48%), Gaps = 5/188 (2%)
 Frame = +3

Query: 51  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230
           V ITGA+TGIG  + RI    G  +  ++   +E       EL      K    + D++ 
Sbjct: 3   VLITGASTGIGYEITRIFARNG--YDVVITARDE---KRLIELAKNINTKVTVIKKDLSR 57

Query: 231 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 410
            +    + N + +    +D+++NNA  M D+ G++ K+    +  ++   +K++ I+ + 
Sbjct: 58  PDSANELFNEIKENNIEVDILVNNAG-MGDT-GLFHKSSVDKINEMLELNIKSLTILTRL 115

Query: 411 SGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
                   + G ++NV+S  +      + +Y+ATK+ VL F+  IG  E   K  V+V  
Sbjct: 116 VSAEMVKKRSGMILNVASTGSYMPGPFIAVYYATKAYVLSFTEAIG--EELKKFNVKVSA 173

Query: 576 VCLGATDT 599
           +C GAT T
Sbjct: 174 LCPGATAT 181


>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 254

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KVV ITG A GIG++  ++LLD G K +A++DI E++    +  L+ +  ++      +V
Sbjct: 4   KVVLITGGAGGIGQATAKLLLDYGAK-VALVDINEDSLVKAKESLHVE-DDRVFTITGNV 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383
           T EE     +   V   G IDV  NNA +      I       ++K + +NVT +     
Sbjct: 62  TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLK 121

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
             ++ M K      G+++N +S AA   S  M  Y A+K AV   +         +  G+
Sbjct: 122 HVMKQMKKQG---YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAAL--EVASDGI 176

Query: 564 RVLTVCLGATDTALLTD 614
           RV  V   A DT +L D
Sbjct: 177 RVNAVAPAAIDTQMLAD 193


>UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=1;
           Oceanobacter sp. RED65|Rep: Putative fatty acyl chain
           reductase - Oceanobacter sp. RED65
          Length = 252

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 48/194 (24%), Positives = 98/194 (50%), Gaps = 6/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K+V ITG +  +G + V     +  +     + ++++   L A      G +    R ++
Sbjct: 10  KIVLITGGSGDLGRASVLEFGKQKCRVYFTYNSSKDSADELVASAEES-GFEAFPIRCNI 68

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 386
           +D+E    ++N +V+++G IDV++NNA +  D++        +++ I+ N+      T  
Sbjct: 69  SDKEQVNALVNDIVEKEGKIDVLVNNAGIYKDNLFTSMTDEEFEQVIQTNLYGTFYCTKS 128

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
            +++M ++   + G ++NVSS+A +T S     Y A K AV+ FS  +      +   +R
Sbjct: 129 VVDVMYRN---RCGAIVNVSSIAGVTNSFGQANYSAAKGAVVSFSRTLA--AELAPKNIR 183

Query: 567 VLTVCLGATDTALL 608
           V TV  G  D++++
Sbjct: 184 VNTVAPGLIDSSMV 197


>UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Acidobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 257

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 53/193 (27%), Positives = 93/193 (48%), Gaps = 3/193 (1%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  + G  TGIG ++   L D G   ++     E+   +  A+   + G +T    SDV
Sbjct: 10  KVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAA--ADEIERRGRQTLRVCSDV 67

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAIEI 398
           T       + NAV+ +   +D+++N A     +  +     E N  +   +T  L+A ++
Sbjct: 68  TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPTLTVSEDEWNKILDTNLTGALRACQV 127

Query: 399 MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
            GKH   +G G +IN++S+++    H +  Y A+K+A+L  +  +     +SK GV V  
Sbjct: 128 FGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLA--VEWSKKGVTVNA 185

Query: 576 VCLGATDTALLTD 614
           +  G   TAL T+
Sbjct: 186 IAPGVFRTALNTE 198


>UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2;
           Bacteria|Rep: Cyclopentanol dehydrogenase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 355

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 58/194 (29%), Positives = 93/194 (47%), Gaps = 6/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITG A G GE+  R+    G  H+ I D+ EE G+ L AEL    G +  F   DV
Sbjct: 102 KVALITGGARGQGEAEARLFAQHGA-HVYICDVLEEEGEKLAAELRGS-GLQADFRFLDV 159

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIG-IYKKAIEVNVTALITSTLK 386
           TD E +   +  +    G +DV+INNA +     + D+    + + + VN    +   ++
Sbjct: 160 TDAEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLG-MQ 218

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A   + K SG   G++IN+ S A +   H +  Y A+K AV   +         + +G+R
Sbjct: 219 ACAPLMKRSG--NGSIINIGSTAGI-MGHPVAAYSASKWAVRGLTKAAAM--ELASSGIR 273

Query: 567 VLTVCLGATDTALL 608
           V  +  G  +T ++
Sbjct: 274 VNAMHPGVVETPMV 287


>UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Stappia aggregata IAM 12614|Rep: Short-chain
           dehydrogenase/reductase SDR - Stappia aggregata IAM
           12614
          Length = 270

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 54/200 (27%), Positives = 95/200 (47%), Gaps = 8/200 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +V  +TGA+ GIGE+  R L   G K + +   +++  + +  E+ ++ G        DV
Sbjct: 24  QVALVTGASRGIGEAAARSLAKYGAK-VVLAARSDKDIERIAGEIRAE-GQDATAVVCDV 81

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383
            D +  +  +   V   GG+D+++NNA ++     I       + K I++NV  +     
Sbjct: 82  ADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVIDINVKGVYYG-- 139

Query: 384 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
             +    KH   KG GTV+N+SS AA++       Y A+K+A L  + C  +   F   G
Sbjct: 140 --LHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK--EFGDKG 195

Query: 561 VRVLTVCLGATDTALLTDEK 620
           +R++ +  G   T +  D K
Sbjct: 196 LRIVGLSPGTVATQMQVDIK 215


>UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=2; Halobacteriaceae|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 254

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 55/211 (26%), Positives = 98/211 (46%), Gaps = 9/211 (4%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGQSLQAELNSKYGNKTKF 209
           +DKV  +TG A+G G ++ R   + G   + + D  +   E G+     + ++      F
Sbjct: 6   EDKVAVVTGGASGFGRAICRRYAEHGA-DVIVADRQQDPREGGKPTHELVEAETDRTAHF 64

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 371
              DVTD +  L +  A  +E GGID+++NNA +         +   Y + ++VN   + 
Sbjct: 65  VECDVTDPDD-LEVAVAAAEELGGIDIMVNNAGISEIADFYETTEEDYDRLMDVNTKGVF 123

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
                A E M ++    GGTVIN+SS   +  + ++  Y  +K AV  F+  +   +  S
Sbjct: 124 FGAQVATEAMRENG---GGTVINMSSSGGIRGTGLLVNYCTSKGAVRLFTYALA--DRLS 178

Query: 552 KTGVRVLTVCLGATDTALLTDEKLGTFDKYL 644
              +RV  +  G + T +  DE++    K +
Sbjct: 179 NYNIRVNAIHPGYSKTQMFEDERIDDTTKMM 209


>UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;
           n=13; Bacteria|Rep: Uncharacterized oxidoreductase
           SSP1627 - Staphylococcus saprophyticus subsp.
           saprophyticus (strain ATCC 15305 /DSM 20229)
          Length = 246

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 58/196 (29%), Positives = 91/196 (46%), Gaps = 7/196 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYR 215
           KDKVV ITGA++GIGE  V +L + G K    L +       L+ ++  K G +     +
Sbjct: 5   KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 377
           +DVT  +    ++     + G IDV+INNA LM  S         + + I+VN+  ++  
Sbjct: 60  TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
               +  M K    K G +IN++SVA         +Y  TK AV   +  + + E    +
Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGS 176

Query: 558 GVRVLTVCLGATDTAL 605
            +R   +  GA  T L
Sbjct: 177 NIRTTILSPGAVSTEL 192


>UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate
           dehydrogenase; n=31; Bacteria|Rep:
           2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase -
           Bacillus subtilis
          Length = 261

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 51/188 (27%), Positives = 91/188 (48%), Gaps = 3/188 (1%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K+ FITGAA GIGE+V R L  +G  HIA +D   E  + + + L ++     + + +DV
Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADV 66

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYKKAIEVNVTALITSTLKAIEI 398
            D      I   + +E G ID+++N A ++   +   +  +  E   +   T    A   
Sbjct: 67  RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126

Query: 399 MGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
           + K+    + G+++ V S  A      M  Y ++K+A + F+ C+G     ++  +R   
Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL--ELAEYNIRCNI 184

Query: 576 VCLGATDT 599
           V  G+T+T
Sbjct: 185 VSPGSTET 192


>UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to
           ENSANGP00000025535; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000025535 - Nasonia
           vitripennis
          Length = 254

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 57/201 (28%), Positives = 100/201 (49%), Gaps = 8/201 (3%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           W  KV  +TGA+ GIG ++V  LLD G   + ++ +A    + ++  ++ +   K     
Sbjct: 4   WAGKVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRV-EKVKELIDDRPEAKLHAVE 59

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 377
            DVT+EE+ +     + +  G +DV++NNA       L + S+  ++  ++VNV  L   
Sbjct: 60  CDVTNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVC 119

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV--MPIYFATKSAVLQFSNCIGRPEHFS 551
           T +A+  M +  G     +I++SS+A      V    +Y ATK AV   +  + R E  +
Sbjct: 120 TREAVRSMRECDG--ESVIIHISSLAGERVPAVPGFNVYPATKRAVNALAQTL-RHE-LA 175

Query: 552 KTGVRVLTVCLGATDTALLTD 614
            T +RV T+  G   T L+ +
Sbjct: 176 GTKIRVTTISPGLVATELMAN 196


>UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep:
           Bll5898 protein - Bradyrhizobium japonicum
          Length = 256

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 62/201 (30%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M   +KDKVV +TGA +GIG +  R    EG   I +L+   E   S  AE+ ++ G   
Sbjct: 1   MLSRFKDKVVIVTGAGSGIGAAAARRFHGEGA--IVVLNGRRE---SKLAEVGAELGTDR 55

Query: 204 KFYR-SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVT 362
              R +DVT       ++   V+  G ID+++NNA        +   I  ++    VNV 
Sbjct: 56  CMIRPADVTIAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVD 115

Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542
            ++  T  A+     H    GG+++NVSS++ L     +  Y ATK AV   +  +    
Sbjct: 116 GVLYMTRAAL----PHLIESGGSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLAL-- 169

Query: 543 HFSKTGVRVLTVCLGATDTAL 605
            F   GVR+  VC   T T L
Sbjct: 170 EFGPRGVRINAVCPSLTLTHL 190


>UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=3; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
           sp. (strain RHA1)
          Length = 258

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 6/184 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K + +TG A GIG ++V+    EG   +   D+ EE G+ +  E +       +F R D+
Sbjct: 6   KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 386
           TD +    +  +  +E GGIDV++N A L   ++       +++    VNV   I +   
Sbjct: 65  TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A  IM   S G  G +IN  S++  T       Y ++K AV  ++  + R   +  +G+R
Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFTGELANATYGSSKGAVHTWTRTVAR--EWGPSGIR 179

Query: 567 VLTV 578
           V  V
Sbjct: 180 VNAV 183


>UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 261

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 13/205 (6%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 227
           +  ITGA++GIG  + R+   +G   I +    +   Q L AEL + +  K +   +D+ 
Sbjct: 5   MALITGASSGIGAELARLCAADGYGLILVARRTDRLEQ-LGAELAAAHNVKFRTIAADLA 63

Query: 228 DEEHFLGILNAVVQEQGG--IDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 383
           + +       A+ ++  G  ID++INNA                 + I+VN+TAL   T 
Sbjct: 64  EPD----AATAIYRQTSGDTIDILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTK 119

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
             ++ M +   G+   ++NV S AA     +M +Y+A+K+ V+ FS  + +   F  TGV
Sbjct: 120 SYVKDMVRRGSGR---ILNVGSTAAFVPGPLMAMYYASKAFVVSFSEALAK--EFEGTGV 174

Query: 564 RVLTVCLGATDT-----ALLTDEKL 623
            V  +C G T T     A +TD KL
Sbjct: 175 TVTVLCPGPTRTEFDAAAGITDSKL 199


>UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=1;
           Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Algoriphagus
           sp. PR1
          Length = 265

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 49/181 (27%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV+ +TG+ TGIG+++ + ++ EG K + I  + E+ GQ + +EL +   +  K +  D+
Sbjct: 6   KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 386
           ++E     +++  V+  G +D ++NNAA++  S           + +EVN  +    T  
Sbjct: 62  SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           AI  + ++     G V+N+ S+ A +  H +  Y  +K A++  +  +G    F + GVR
Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLG-DSLFRENGVR 176

Query: 567 V 569
           V
Sbjct: 177 V 177


>UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Nocardioides sp. (strain
           BAA-499 / JS614)
          Length = 259

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 8/205 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M+   + +V  ITG  +GIG + V+  + EG K + I DI +  G  L  +L     +  
Sbjct: 1   MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAK-VVIGDIDDARGHQLVEQLGG--ADVA 57

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNV 359
            +   DVT +E    +        G +D+  NNA        ++++  +  ++K  EVN+
Sbjct: 58  TYVHVDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNL 117

Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 539
           T++      A+  M +   G+G  +   S VA +  +     Y A+K  VL  +  +G  
Sbjct: 118 TSVYLCCKAALPHMLEQ--GRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELG-- 173

Query: 540 EHFSKTGVRVLTVCLGATDTALLTD 614
             F++ GVRV  +C G  +T LL +
Sbjct: 174 VQFARQGVRVNALCPGPVNTPLLQE 198


>UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Paracoccus
           denitrificans (strain Pd 1222)
          Length = 253

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 7/195 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M    KDKVV ITGA  GIG +  ++ ++EG + + + D   +A + + AEL    G   
Sbjct: 1   MDMHLKDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENA 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 365
           + +  DV+  E    +++  V E GG+DV++NNA       +       ++  I+VN+T 
Sbjct: 56  RAFTVDVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTG 115

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQS-HVMPIYFATKSAVLQFSNCIGRPE 542
           +   +  A+  + K     GG ++N +S  A+  +      Y A K  V   +  +    
Sbjct: 116 VYLCSKYAVPELRKRG---GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMAL-- 170

Query: 543 HFSKTGVRVLTVCLG 587
            F+   +RV +V  G
Sbjct: 171 DFAADNIRVNSVAPG 185


>UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2080
          Length = 291

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 49/181 (27%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K + ITGAA+G+G ++ +    EG   + I DI +E G  + A+LN +Y N   F   ++
Sbjct: 2   KRILITGAASGLGLALAKKYASEGWS-VCIADIQDEEGIKIAAQLNEEYANDCFFQHLNI 60

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-KAIEVNVTALITSTLKAIEI 398
           T +  +  ++  + +   G+D ++NNA +  +  I  +  K  +  V   +   +K   +
Sbjct: 61  TSDTQWQELVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHV 120

Query: 399 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 578
                    G +INV+S+A L     M  Y  +K+ ++ FS   G        GV+V  V
Sbjct: 121 CVPLLKESKGLLINVASMAGLLHMGSMSAYNVSKAGMVAFSE--GLLSELDPYGVKVSVV 178

Query: 579 C 581
           C
Sbjct: 179 C 179


>UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1;
           Mycobacterium ulcerans Agy99|Rep: Short-chain
           dehydrogenase - Mycobacterium ulcerans (strain Agy99)
          Length = 282

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 56/191 (29%), Positives = 91/191 (47%), Gaps = 4/191 (2%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +VV ITGA +GIG  +  +    G   +A+ DI + A     A+    +G+     R DV
Sbjct: 16  RVVAITGAGSGIGRELALLCAQRGAD-LALCDINDTAVADT-AQTARGFGHDVITRRVDV 73

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAIE- 395
           +D E      +A +   GG+D+++NNA   L+   +   +K  +  V+  +   +   E 
Sbjct: 74  SDPEQMTAFADATLGHFGGVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVHGCEA 133

Query: 396 -IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
            +      G+GG V+N+SS A L  +  +  Y ATK AVL  S  + R E      + V 
Sbjct: 134 FLPAMIESGRGGHVVNLSSAAGLLANPALSAYSATKFAVLGLSEAL-RIE-LEPHRIGVT 191

Query: 573 TVCLGATDTAL 605
            +C G  +TA+
Sbjct: 192 AICPGVINTAI 202


>UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 284

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 66/220 (30%), Positives = 99/220 (45%), Gaps = 19/220 (8%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS--KYGNKTKFYR 215
           DKV  ITG++ GIG++  R+L  EG K       AE   ++    L +    GN      
Sbjct: 6   DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 365
            D+T E     ++ + + + G ID+++NNA            +N SI  Y K  E+NV +
Sbjct: 65  GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPE 542
           +I  T KA      H     G ++N+SS+ A   + V  P Y   K+A+ Q++       
Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAA--I 178

Query: 543 HFSKTGVRVLTVCLGATDTAL------LTDEKLGTFDKYL 644
                G+RV +V  GA  T        LT+EK   F  YL
Sbjct: 179 DLVPEGIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYL 218


>UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3;
           Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 -
           Eubacterium sp. (strain VPI 12708)
          Length = 249

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 50/194 (25%), Positives = 92/194 (47%), Gaps = 7/194 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF-YR 215
           +DK+  ITG   GIG +  ++ ++ G K ++I    +E   +  A+L   Y  +    + 
Sbjct: 5   QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 377
            D+T  +  +  +  V Q+ G +DV+INNA +  +S+        +K  +++NV  +   
Sbjct: 64  PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
              A + M      K G +IN +SV  +  S     Y  +K+ V+  ++ +GR     + 
Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGR--EIIRK 178

Query: 558 GVRVLTVCLGATDT 599
            +RV+ V  G  DT
Sbjct: 179 NIRVVGVAPGVVDT 192


>UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=25; Proteobacteria|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Burkholderia mallei (Pseudomonas mallei)
          Length = 265

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 49/170 (28%), Positives = 89/170 (52%), Gaps = 8/170 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG-QSLQAELNSKYGNKTKFYR-S 218
           K  FITGAA G+G ++ R + ++G + + + DI + A  ++  AELN   G +  +    
Sbjct: 14  KRAFITGAAGGLGRAIARRMAEQGAQ-VFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQ 72

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-DSIG-----IYKKAIEVNVTALITST 380
           DV DE  +   L+      GG+ V+++NA + +  +IG      +++ + +NV +++  T
Sbjct: 73  DVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGT 132

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 530
             A+  +     G   +++N+SSVAA  Q      Y A+K+AV   +  I
Sbjct: 133 KHALPYL---EAGAPASIVNISSVAAFKQEPDYTAYNASKAAVASLTKSI 179


>UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like
           protein; n=1; Hahella chejuensis KCTC 2396|Rep:
           Short-chain alcohol dehydrogenase-like protein - Hahella
           chejuensis (strain KCTC 2396)
          Length = 288

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 54/198 (27%), Positives = 95/198 (47%), Gaps = 6/198 (3%)
 Frame = +3

Query: 30  HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 209
           H + +K V ITGAA+G+G +  R  L  G + +A  D+ +E G ++ A L     N+  +
Sbjct: 2   HRFPEKRVAITGAASGLGLATARHFLSRGWR-VAFADVQDETGSAIVASLGLP-ENRAFY 59

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG-----IYKKAIEVNVTALI 371
              DVT           +V+  GG+D++INNA +  +  IG      ++  I++++  ++
Sbjct: 60  QHVDVTKVRDIQAWRRKIVETWGGLDILINNAGVAAHGGIGEAPLEDWEWVIDIDLMGVV 119

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
               +   +  +    + G ++N++S+A L  +  M  Y A K+ V+  S  +      S
Sbjct: 120 RGCKEFAPLFKRQ---RSGQIVNIASMAGLVHAPEMGSYNAAKAGVVALSETL--VGELS 174

Query: 552 KTGVRVLTVCLGATDTAL 605
             GV V  VC G   T L
Sbjct: 175 PFGVGVNVVCPGFFSTGL 192


>UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Bacillus thuringiensis serovar
           israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Bacillus thuringiensis serovar
           israelensis ATCC 35646
          Length = 252

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 47/201 (23%), Positives = 97/201 (48%), Gaps = 6/201 (2%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           ++K + +TG   GIG ++V   L EG    A    ++++   +++EL S Y ++   Y  
Sbjct: 11  ENKRIIVTGGCKGIGRAIVEKYLQEGAVVAATYYKSKDSSDQMKSELES-YSDRLAIYNM 69

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 380
           DV+D E    ++  +  +  GID+++NN+ +  DS+        + K I+ N+     + 
Sbjct: 70  DVSDAEQVNKVMEQIQDDLKGIDILVNNSGITQDSLLYSMKNSDWDKVIKTNLYGPFYTC 129

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
              +  M K    K G++IN++SV+ +        Y A+K  ++  +  + +    +   
Sbjct: 130 KSVLLNMIKQ---KYGSIINIASVSGIVGIPGQSNYCASKFGLIGLTKSLAK--ELASKN 184

Query: 561 VRVLTVCLGATDTALLTDEKL 623
           +RV  +  G  DT ++ + K+
Sbjct: 185 IRVNAIAPGYVDTEMIDNVKI 205


>UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Polaromonas sp. JS666|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 265

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 59/209 (28%), Positives = 102/209 (48%), Gaps = 7/209 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M  + K+K V +TG  + IG ++V     EG  HI I D+ E+  Q   AEL    G  +
Sbjct: 1   MDIDLKNKSVIVTGGGSNIGRAIVLGFAAEGA-HITIGDVDEQQAQKT-AELALLSGAAS 58

Query: 204 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA---LM---NDSIGIYKKAIEVNVT 362
            +  ++DVT  +    +  A V + GG+DV++NN     LM     +  +++K I +N  
Sbjct: 59  AQVVKTDVTQLDQVQAMFKAAVDKFGGVDVLVNNVGWDQLMFFTQTTPDLWQKIIAINYV 118

Query: 363 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 542
            ++  T  A+++M   +    G+++++SS A+        +Y   K+A+  F   I +  
Sbjct: 119 GVLNCTKTALDLMIPRN---AGSIVSISSDASRQGEPREAVYGGVKAAINSFMKTIAKEN 175

Query: 543 HFSKTGVRVLTVCLGATDTALLTDEKLGT 629
              + G+R   VC G T  +  TDE  G+
Sbjct: 176 --GRYGIRCNVVCPGITIPS-TTDEVGGS 201


>UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 249

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 53/197 (26%), Positives = 97/197 (49%), Gaps = 6/197 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS +   +V  +TGA++G GE+V   L   G K +A+    E+  ++L A+  +  G + 
Sbjct: 1   MSMDLSGRVALVTGASSGFGEAVALDLAKAGAK-VALAARREDRLRAL-AQRITDAGGQA 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 365
           +   +D TDE      +       G +D++INNA +M         +G ++  +E+N+  
Sbjct: 59  QVIVADFTDEHQAQRAVRETEAAFGWLDILINNAGVMYLEPVATADLGRWRSMLELNLLG 118

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           LI +T  A+  M   +  K G ++N++S A    + +   Y A+K  V+ FS  + +  H
Sbjct: 119 LIAATQAALPGM---TARKDGHIVNIASTAGHIANPLSAAYSASKFGVIGFSESLRKEVH 175

Query: 546 FSKTGVRVLTVCLGATD 596
                V V++  + AT+
Sbjct: 176 KDNIRVTVISPGMAATE 192


>UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 254

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 57/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
 Frame = +3

Query: 18  LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN 197
           + ++   K KV  ITGAA G+GE++ R  +  G   + I D+  E G+++ A++ ++ G 
Sbjct: 1   MSVNDSLKGKVAIITGAAQGLGEAIAREFVARGAA-VIITDVQREEGEAVAADILAQ-GG 58

Query: 198 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNV 359
           K  F   DV D E +  ++   +   G +DV++NNA L+  +      I ++ +   VNV
Sbjct: 59  KALFIAHDVGDAEAWDVVVAKALDTFGKVDVLVNNAGLIQFAPLEEMPIEMFDRVTRVNV 118

Query: 360 TALITSTLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGR 536
                   KAI    K +G  GG +IN+SS+   + Q+  +  Y  +K AV   +  +  
Sbjct: 119 RGPWLG-CKAILPALKAAG--GGAIINMSSMNGMIAQNPGLSAYATSKGAVRMLTKAVA- 174

Query: 537 PEHFSKTGVRVLTV 578
            + + + GVRV +V
Sbjct: 175 -QDYVQYGVRVNSV 187


>UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales
           bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales
           bacterium HTCC2150
          Length = 279

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 54/199 (27%), Positives = 96/199 (48%), Gaps = 7/199 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGQSLQAELNSKYGNKTKFYR 215
           K+K V +TGAA G+G +     L +G  ++ + D+ AE+  +S+Q  +  ++        
Sbjct: 23  KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 389
            DVT  E+   ++   V   G +DV+INNA +  + D + I     +  +   +      
Sbjct: 80  CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139

Query: 390 IEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN--CIGRPEHFSKT 557
            +I GK   + GKGG +IN+SS+ AL  + ++  Y  +K  + Q +N   +G   H    
Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPH---- 195

Query: 558 GVRVLTVCLGATDTALLTD 614
            +RV  +  G   T ++ D
Sbjct: 196 NIRVCGIGPGTILTDMVAD 214


>UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Rep:
           RH03309p - Drosophila melanogaster (Fruit fly)
          Length = 247

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 53/204 (25%), Positives = 99/204 (48%), Gaps = 13/204 (6%)
 Frame = +3

Query: 36  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYR 215
           W + V  +TGA++GIG ++ R L+  GV  +A+    +   Q L+ EL     ++ +  +
Sbjct: 4   WHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQ-LREELPQDRRSRLRIMQ 62

Query: 216 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 377
            DV+D      + +AV  + G +D++INNA       L+  S+   ++ ++ NV  ++  
Sbjct: 63  CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYC 122

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP-------IYFATKSAVLQFSNCIGR 536
           T +A E M +      G V+ ++S+      + +P       +Y ATK A+   +    +
Sbjct: 123 TQRAFESMRQRQ--SKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQ 180

Query: 537 PEHFSKTGVRVLTVCLGATDTALL 608
                KT V+V ++  G  DT L+
Sbjct: 181 EMRDFKTKVKVTSISPGLVDTELV 204


>UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular
           organisms|Rep: Oxidoreductase - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 260

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 58/200 (29%), Positives = 91/200 (45%), Gaps = 6/200 (3%)
 Frame = +3

Query: 30  HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 209
           HE    V  +TGA++GIGE+    L  EG   +     A+E   +L   +    G+    
Sbjct: 16  HELAGDVAIVTGASSGIGEATAEALAAEGAHVVLAARRADELA-ALADRIEDTDGDAL-V 73

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALI 371
             +D+TD++    +++  V E G ID+++NNA +M             ++ +EVN+  L+
Sbjct: 74  VPTDITDDDAIDDLVSETVDEYGRIDILVNNAGVMLLEPLERADRSNLRQMVEVNLLGLM 133

Query: 372 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 551
             T   + IM     G    V+NVSSVA          Y ATK  V  F++ I   +  +
Sbjct: 134 NLTHAVVPIMQDQDAGH---VVNVSSVAGRQADADSSGYNATKFGVNAFTDAI--RQELT 188

Query: 552 KTGVRVLTVCLGATDTALLT 611
              +R   +  GA DT L T
Sbjct: 189 SQDIRTTIIEPGAVDTELST 208


>UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid
           dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or
           20-beta)-hydroxysteroid dehydrogenase - Mycobacterium
           bovis
          Length = 260

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 6/200 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS     KV  ++G A G+G S VR ++ EG K +   DI +E G+++ AEL     +  
Sbjct: 1   MSGRLIGKVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAA 55

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 365
           ++   DVT    +   ++  V   GG+ V++NNA ++N       ++  +++ ++VN+T 
Sbjct: 56  RYVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTG 115

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           +       ++ M K +G   G++IN+SS+  L  +     Y ATK AV   +        
Sbjct: 116 VFLGIRAVVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--E 170

Query: 546 FSKTGVRVLTVCLGATDTAL 605
              +G+RV ++  G   T +
Sbjct: 171 LGPSGIRVNSIHPGLVKTPM 190


>UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 240

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 4/152 (2%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQ---AELNSKYGN-KTKF 209
           +KV  +T    GIG S   + L    +++A+LD+ +     +      L  ++G  K  +
Sbjct: 5   NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62

Query: 210 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 389
           Y  +V + E F  +   VV+ +G +D+++ NAA+  D+       I+VN+  +I  TL A
Sbjct: 63  YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120

Query: 390 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 485
           +E MG H   KGG V+N++S   L  +  + +
Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGLEHNKFLGV 152


>UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase;
           n=11; Proteobacteria|Rep: D-beta-hydroxybutyrate
           dehydrogenase - Bradyrhizobium japonicum
          Length = 249

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 50/193 (25%), Positives = 91/193 (47%), Gaps = 4/193 (2%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           K   V +TGAA+G+G +  R+   EG  ++A+ D  E+   S+  E+ +  G   K ++ 
Sbjct: 2   KGLTVLVTGAASGMGRATARVFAAEGA-NVAVTDYDEQGAISVAKEIAAS-GGSAKAWKL 59

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG--IYKKAIEVNVTALITSTLKA 389
           DV D      +++ V    GG+D+V+NNA + +  +I    Y+ A    +  ++T+  + 
Sbjct: 60  DVADGGEIKRVVHDVAAHFGGLDIVVNNAGISVRVAIDDETYEDAWARGIAVMLTAHPRI 119

Query: 390 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           I     H    K   ++N++S  AL  + +   Y A K  V   +  +       + G+ 
Sbjct: 120 IRAALPHLRKSKSPRIVNIASTEALGATALHSPYSAAKGGVASLTRSLA--VELGREGIT 177

Query: 567 VLTVCLGATDTAL 605
           V  +C G   TA+
Sbjct: 178 VNCICPGPIRTAI 190


>UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Polaromonas sp.
           (strain JS666 / ATCC BAA-500)
          Length = 249

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 5/191 (2%)
 Frame = +3

Query: 51  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230
           V +TGA TGIG +       +G  ++ +    EEAGQSL AEL +  G K +F ++DV +
Sbjct: 6   VLVTGALTGIGRATAIAFAKQGA-NVVVSGRREEAGQSLAAELRT-LGAKAEFIKADVAN 63

Query: 231 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 410
           E     ++   V   G +D+ INNA     ++G   +    NV A  ++ +    +  KH
Sbjct: 64  EAEVRSLVEKAVSLFGQLDIAINNAG-TEGALGPITEQSTENVHATFSTNVLGTLLSMKH 122

Query: 411 S----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 575
                  +G G+++N+SS+A         +Y A+K AV   +         +  GVRV  
Sbjct: 123 EIRAMQAQGHGSIVNLSSIAGKVGMAGASVYVASKHAVEGLTKSAAL--EGAAFGVRVNA 180

Query: 576 VCLGATDTALL 608
           V  G   T +L
Sbjct: 181 VAPGPVQTDML 191


>UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MWYL1
          Length = 256

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           KD+ VFI+G ATGIG ++V     +G K  A +D+ E+AG +L   L +K G   +F   
Sbjct: 13  KDRSVFISGGATGIGAAIVEAYAKQGAK-TAFVDLDEKAGTALAKRL-TKDGYDVRFEVC 70

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 386
           D+TD + +   + A  +  G I V++NNAA  ND     +   E     L+   +K    
Sbjct: 71  DITDIQDYQSKIRAAAEVFGPITVLLNNAA--NDVRHSLESLTEERFDELVGVNIKHAMF 128

Query: 387 ---AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
              A+  M +  G  GG++IN  SV  +  +   P Y  +K+A    +  + R       
Sbjct: 129 AAQAVAPMMRKLG--GGSIINFGSVGWMMATAGYPTYGTSKAATHGLTRSLAR--DLGGF 184

Query: 558 GVRVLTVCLG 587
           G+RV T+  G
Sbjct: 185 GIRVNTLVPG 194


>UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
          Length = 273

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 57/196 (29%), Positives = 95/196 (48%), Gaps = 8/196 (4%)
 Frame = +3

Query: 57  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELN-SKYGNKTKFYRSDVTDE 233
           +TGAA+GIG ++   LL +    +   DI  EA   + A    +  G      + DV D 
Sbjct: 7   VTGAASGIGRALCERLLTDKGNQVCACDINYEALTQIYANHKLADAGGSLILRQLDVRDV 66

Query: 234 EHFLGILNAVVQEQGGIDVVINNAALMNDS----IGIYKKA---IEVNVTALITSTLKAI 392
           + +  ++N V+ +   IDV+ N A ++ D+    I +        ++NV   I  T   +
Sbjct: 67  QQWQEVVNTVIAQWQRIDVMCNIAGVLKDNWIADIALPDDVDLHFDINVKGTIFGTQSVV 126

Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
           + M ++ G   G +INV+S+AAL+    + +Y A+K AV  +S   G      K G+ V 
Sbjct: 127 DTM-RNQGS--GHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAGM--ELEKYGIAVT 181

Query: 573 TVCLGATDTALLTDEK 620
           T+C  A  T +L  +K
Sbjct: 182 TLCPDAVQTPMLDQQK 197


>UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Mycobacterium gilvum PYR-GCK|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium gilvum
           PYR-GCK
          Length = 260

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 55/199 (27%), Positives = 99/199 (49%), Gaps = 9/199 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K V ITGAA+GIG +  ++++ EG + + I D+  +A  +  +++    G       ++V
Sbjct: 9   KRVVITGAASGIGRAAAQLMIGEGAR-VLIADLDADAAAAAASDI----GGNAIGVAANV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA---------LMNDSIGIYKKAIEVNVTALITS 377
            D++    +++  V E GGIDV+ N+           L+   +  + +A+ +N  + + +
Sbjct: 64  LDDKSVAAMIDRAVTEFGGIDVLCNHVGGSNPHKDLDLLRLDLDEWDRAMALNARSTVVA 123

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
           +  A+  M    GG   ++IN  SVA LT   +   Y A+K+AV++ +  I     + + 
Sbjct: 124 SRLALPHMIAEGGG---SIINTVSVAGLTGDTLQCAYGASKAAVIRLTQYIA--TQYGRK 178

Query: 558 GVRVLTVCLGATDTALLTD 614
           GVR   V  GA  T  L D
Sbjct: 179 GVRCNAVAPGAVMTPALAD 197


>UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2;
           Actinobacteria (class)|Rep: Putative short chain
           dehydrogenase - marine actinobacterium PHSC20C1
          Length = 265

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 56/192 (29%), Positives = 90/192 (46%), Gaps = 6/192 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           M+H  K++ V ITG  +GIG  +     + G + + + D++  A +S+  E+    G+  
Sbjct: 1   MTHPLKNQTVLITGGGSGIGRLLALGAAERGAR-VVVWDLSAAAAESVCEEILGA-GHHA 58

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 365
           + +  DV+D       +NA  ++ G +DV+INNA       L++ S    ++ I VN  A
Sbjct: 59  EAFTVDVSDRN----AVNAAAKKTGQVDVLINNAGIVTGKNLLDASDEAIERTIRVNTLA 114

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           L   T      +G     + GTV+ +SS A L        Y A+K A L F+  +     
Sbjct: 115 LFWVTRA---FLGNMIANRRGTVVTISSAAGLVGVAKQTDYSASKFAALGFAESLRVELS 171

Query: 546 FSKTGVRVLTVC 581
              TGV  L VC
Sbjct: 172 KENTGVNSLVVC 183


>UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:
           Acetoin reductases - Mycobacterium sp. (strain KMS)
          Length = 285

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 9/194 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGA  GIG  +   L  +G   IA++D++E       AE+ S+ G+KT  + +DV
Sbjct: 27  KVALVTGAGRGIGRGIAVELARQGAD-IALVDVSEAGLPDAAAEI-SEIGSKTTTFVADV 84

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGIYKKAI----EVNVTAL---ITS 377
            D +     ++      GG DV++NNA  AL+     +  + +     +NV  +   I +
Sbjct: 85  RDRDAVFAAVDHAAAALGGFDVMVNNAGIALVGPIAEVTAEDLARLWAINVDGVLWGIQA 144

Query: 378 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
                + +G H+ GK   +IN SS+A      ++  Y ATK AV   +    +   ++  
Sbjct: 145 AAAKFKELGNHAEGKVSKIINASSIAGHEGFAMLGPYSATKFAVRALTQAAAK--EYAAD 202

Query: 558 GVRVLTVCLGATDT 599
           G+ V   C G   T
Sbjct: 203 GITVNAYCPGVVGT 216


>UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella woodyi ATCC
           51908
          Length = 255

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 49/185 (26%), Positives = 94/185 (50%), Gaps = 6/185 (3%)
 Frame = +3

Query: 51  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 230
           VFITG A+GIG ++VR  +++G  ++  +D   +AG++L   L+   G +  F+  DVTD
Sbjct: 15  VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73

Query: 231 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 392
            +    ++    Q+ G +D++INN      +D+ G+    +K+ + +N+ +   ++  A 
Sbjct: 74  TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133

Query: 393 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 572
            +M +    K G +IN SS  A      M  Y   K+ +   +  + +   + ++ VRV 
Sbjct: 134 LVMKQR---KQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAK--DYGESRVRVN 188

Query: 573 TVCLG 587
            +  G
Sbjct: 189 AIVPG 193


>UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:
           Os07g0665000 protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 310

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 52/209 (24%), Positives = 98/209 (46%), Gaps = 9/209 (4%)
 Frame = +3

Query: 6   IYGTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNS 185
           ++ +   S +   KV  ITGAA+GIGE+  +  +  G K + I DI ++ G+++ AEL +
Sbjct: 33  LFSSSSSSRKLDGKVAVITGAASGIGEATAKEFVRNGAK-VIIADIQDDLGRAVAAELGA 91

Query: 186 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND---------SIGIYK 338
              +   +   DVT E+     ++  V   G +DVV +NA ++            +  Y 
Sbjct: 92  ---DAASYTHCDVTVEKDVAAAVDLAVARHGRLDVVYSNAGVIGAPAPASLAALDLDEYD 148

Query: 339 KAIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQF 518
           + + VN  +++     A  +M      + G ++  +S AA+      P+Y  +K+A++  
Sbjct: 149 RVMAVNARSMLACVKHAARVMAPR---RAGCILCTASSAAVLGGVASPVYSMSKAAIVGM 205

Query: 519 SNCIGRPEHFSKTGVRVLTVCLGATDTAL 605
              + R    ++ GVRV  +   A  T +
Sbjct: 206 VRAVAR--QLARDGVRVNAISPHAIPTPM 232


>UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 387

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 51/185 (27%), Positives = 94/185 (50%), Gaps = 17/185 (9%)
 Frame = +3

Query: 78  IGESVVRILLDEGVKHIAILDIAEEAGQ---SLQAELNSKYGNK-----TKFYRSDVTDE 233
           IG+++   L ++G+  + ++D +EE G+   SL  + N+K+  K       F R DVT+ 
Sbjct: 36  IGKAISLALGEKGI-FVTVVDFSEEGGKEVASLVEKENAKFHPKLGFPSAMFIRCDVTNT 94

Query: 234 EHFLGILNAVVQEQGGIDVVINNAAL---------MNDSIGIYKKAIEVNVTALITSTLK 386
                     +   GG+D+ +N+A +           ++ G++++ I VN+ A+I  T  
Sbjct: 95  RELAAAFKKHLATYGGLDICVNSAGIGTHEPFHKDQTENSGLWRRTINVNLVAVIDCTRL 154

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           AI+ M   +  K G +IN+ S + L   +V PIY A+K  V+ F+  +     + + G+R
Sbjct: 155 AIQTM--QAAKKPGVIINMGSASGLYPMYVDPIYSASKGGVVLFTRSLA---PYKRHGIR 209

Query: 567 VLTVC 581
           V  +C
Sbjct: 210 VNVLC 214


>UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3;
           Oligohymenophorea|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Tetrahymena
           thermophila SB210
          Length = 260

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 55/204 (26%), Positives = 101/204 (49%), Gaps = 18/204 (8%)
 Frame = +3

Query: 48  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSDV 224
           V  +TG  +G+GE+ V  LL++GV+ + I D  EE G  +Q    +KYG ++ +F + DV
Sbjct: 8   VALVTGGTSGLGEATVYALLEKGVR-VFIADRNEEKGLQIQ----TKYGQDRCRFQKCDV 62

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------------YKKAIEVNVTA 365
           +DE     +++A V   G I +++N+A +++  + +               + + VNV  
Sbjct: 63  SDEAQVKALVDACVATFGAIHILLNSAGVISAGLIVGGKNQDQTIKTEEMNRVLGVNVVG 122

Query: 366 LITST----LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 533
               T    L+ ++    +   + G ++NV+SVA +       +Y A+K A++  +  + 
Sbjct: 123 TFNVTKYVALQMVKQQPLNEFKERGVIVNVASVAGIEGQRGQTVYAASKGAIIGMTLPLA 182

Query: 534 RPEHFSKTGVRVLTVCLGATDTAL 605
           R     K GVRV T+  G   T +
Sbjct: 183 R--DLGKFGVRVCTIAPGIFQTPM 204


>UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
           Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase -
           Oceanobacillus iheyensis
          Length = 244

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 57/197 (28%), Positives = 99/197 (50%), Gaps = 6/197 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           ++KV  ITG A G+G S VR+   EG K +   D+ EE G +L  EL    G   KF + 
Sbjct: 5   ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 380
           DVT+ + +  +++   +  G ++V++NNA       LM  +   Y+K I++N  ++    
Sbjct: 60  DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           +KA+    + +G   G+++N+SS+  +    V   Y  +K AV   +            G
Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAVG--YTDSKFAVRGATKAAA--VQLGGLG 172

Query: 561 VRVLTVCLGATDTALLT 611
           +RV +V  G  +T ++T
Sbjct: 173 IRVNSVHPGVIETPMVT 189


>UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 286

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 48/181 (26%), Positives = 88/181 (48%), Gaps = 6/181 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           +  F+TG   GIG ++  I L E   ++AILDI  E  +     +    G +   + +DV
Sbjct: 10  QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 386
            + +     ++      G +D+++NNA        +  S    +K I++N+ +++ +T  
Sbjct: 68  MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A   M   +GGKGG++INV+S+ A   +    +Y A K+ +  F+  +      S  G+R
Sbjct: 128 AARHMV--AGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMAL--ELSGHGIR 183

Query: 567 V 569
           V
Sbjct: 184 V 184


>UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 274

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 55/200 (27%), Positives = 100/200 (50%), Gaps = 6/200 (3%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS  ++ KV  +TG  +GIG +V   LL  G   + ++   +E+    +    + Y N T
Sbjct: 1   MSDVFEGKVAIVTGGTSGIGYAVSEELLKRGAT-VWVIGSRQESVDKARKSF-AAYKN-T 57

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MND-----SIGIYKKAIEVNVTA 365
           +F   DVT  +   G+++A V++ G +D + NNA + M       ++ ++++AI++N+  
Sbjct: 58  RFLAVDVTVADQVKGMIDACVEKDGRLDYLFNNAGIGMTHPSQYLTLEMWQQAIDLNLWG 117

Query: 366 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           ++     A+ +M      K G ++N SS+A +        Y ATK AV   +  + R E 
Sbjct: 118 VVYGVHFALPVM---LAQKSGHIVNTSSIAGIVPLPSQAAYCATKHAVTALTESL-RYEF 173

Query: 546 FSKTGVRVLTVCLGATDTAL 605
           F + G+   T+C     TA+
Sbjct: 174 FEE-GIAFTTICPSNVATAI 192


>UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34;
           Proteobacteria|Rep: Acetoacetyl-CoA reductase -
           Acinetobacter sp. (strain RA3849)
          Length = 248

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 50/197 (25%), Positives = 90/197 (45%), Gaps = 6/197 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           + KV  +TGA  GIG  + R L+  G K IA +   EE  +    +      +  +F  +
Sbjct: 3   EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 380
           D+ + E     +   +  +G +DV++NNA +  D      S   + + I+ N+  L T T
Sbjct: 63  DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
                +  K    K G ++N+SSV  L        Y A+K+ ++ F+  +   +  +++ 
Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALA--QEGARSN 177

Query: 561 VRVLTVCLGATDTALLT 611
           + V  V  G T T ++T
Sbjct: 178 ICVNVVAPGYTATPMVT 194


>UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member
           10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR
           family member 10 - Homo sapiens (Human)
          Length = 270

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KVV +TG   GIG  +VR  ++ G + + I D  E  G++L+ EL         F   DV
Sbjct: 10  KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 383
           T E+    +++  ++  G +D V+NNA            S   +++ +E+N+    T T 
Sbjct: 64  TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123

Query: 384 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
            A+  + K      G VIN+SS V A+ Q+  +P Y ATK AV   +  +   E  S  G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176

Query: 561 VRVLTVCLGATDTAL 605
           VRV  +  G   T L
Sbjct: 177 VRVNCISPGNIWTPL 191


>UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59;
           cellular organisms|Rep: Acetoin(diacetyl) reductase -
           Klebsiella pneumoniae
          Length = 256

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 6/193 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGA  GIG+++   L+ +G   +AI D  +   +++ +E+N   G +    + DV
Sbjct: 3   KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 386
           +D +     +    +  GG DV++NNA +      +SI   I  K   +NV  +I     
Sbjct: 61  SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120

Query: 387 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 566
           A+E   K   G GG +IN  S A    +  + +Y ++K AV   +    R    +  G+ 
Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176

Query: 567 VLTVCLGATDTAL 605
           V   C G   T +
Sbjct: 177 VNGYCPGIVKTPM 189


>UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1;
           Marinobacter algicola DG893|Rep: Short chain
           dehydrogenase - Marinobacter algicola DG893
          Length = 252

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 7/166 (4%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  +TGA   IGE V R+L  EG   IA++D+     + + A++ +  G + K +  DV
Sbjct: 6   KVAIVTGAGRNIGEEVSRVLSAEGAT-IAVVDLDRSRAEKVAADIVAS-GGQAKPFICDV 63

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-KAIEVNVTALITSTLK----- 386
             E+     + AVV + GG+D+++NN A M+D+  I+   A E N T  IT T       
Sbjct: 64  ASEDQIRATVAAVVDQLGGLDILVNNVA-MSDNKHIFDITAEEWNRTLAITLTAPFLFGK 122

Query: 387 -AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 521
            A + M +H+    G +INVSS +          Y A K  V+  +
Sbjct: 123 YAAQAMVQHAA--DGRIINVSSTSGYYGRDRAIAYTAAKGGVINLT 166


>UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=1; Pedobacter sp. BAL39|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Pedobacter
           sp. BAL39
          Length = 248

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 56/198 (28%), Positives = 95/198 (47%), Gaps = 9/198 (4%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           +KV  ITGAA G+GES  R  + EG K + + D++ EAGQ L  EL    G    F + D
Sbjct: 6   NKVAIITGAAQGMGESHARTFVAEGAK-VILTDVSAEAGQKLADEL----GENAIFIKHD 60

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITST 380
           VT  E +  ++    +  G ++V++NNA ++   +         Y K  ++N  ++    
Sbjct: 61  VTCSEQWAHVVAEAEKAFGHVNVLVNNAGILGPMVKTQELQEADYLKVCDINQHSVFYGM 120

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCIGRPEHFSK 554
              I  M K      G+++N+SS+A +  ++  P   Y A+K AV   +        + +
Sbjct: 121 KAVIPSMIK---AGIGSIVNISSIAGIVANYGFPSLAYVASKFAVRGMTKATA--IEYGE 175

Query: 555 TGVRVLTVCLGATDTALL 608
             +RV +V  G   T ++
Sbjct: 176 KNIRVNSVHPGFIKTPMM 193


>UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=3;
           Bacteroidetes|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Polaribacter
           dokdonensis MED152
          Length = 257

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 62/216 (28%), Positives = 109/216 (50%), Gaps = 13/216 (6%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           KV  ITG++ GIG+++ + L ++G + + I    +EA   +  E   + G  T      +
Sbjct: 12  KVAVITGSSKGIGKAIAKGLAEQGAQ-VVISSRNQEACDEVAKEFKEQ-GLDTIGIACHI 69

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG--------IYKKAIEVNVTALITST 380
             E+    +++  ++  G ID+++NNAA+ N   G        I+ K ++VNV A    +
Sbjct: 70  GKEDQRKNLVDKTIESFGRIDILVNNAAI-NPVFGPIEEVSPEIFDKIMDVNVKA--PWS 126

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           L  + ++      K G++IN++SV ALT    + IY  +K+A+L  +    + + + K G
Sbjct: 127 LSNL-VLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTK--NQAKEWGKYG 183

Query: 561 VRVLTVCLGATDT----ALLTDEK-LGTFDKYLXSS 653
           V+   +C G   T    AL  +EK L   +K L SS
Sbjct: 184 VKANAICPGLIKTKFSAALWQNEKILSKVEKALPSS 219


>UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 253

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 53/196 (27%), Positives = 90/196 (45%), Gaps = 5/196 (2%)
 Frame = +3

Query: 33  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFY 212
           ++  KVV ITG ATGIG +       +G + + + D+ + A ++++  L  + G    F 
Sbjct: 6   DFTGKVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAETVR--LIEESGGTALFV 62

Query: 213 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 392
           R+DVT       ++   V   GG+ V  NNA ++  + G   +  E +    I   LK +
Sbjct: 63  RTDVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGV 121

Query: 393 EIMGKH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 557
            +  K+     +   GG++IN +SVA +     M  Y A K  V+  +        ++  
Sbjct: 122 FLALKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAA--IDYAAA 179

Query: 558 GVRVLTVCLGATDTAL 605
           GVRV  +  G  DT +
Sbjct: 180 GVRVNALAPGLVDTPM 195


>UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella sp. (strain
           ANA-3)
          Length = 253

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 59/206 (28%), Positives = 95/206 (46%), Gaps = 8/206 (3%)
 Frame = +3

Query: 42  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 221
           +K   +TGAA GIG++++R LL EG + +A    A+ +  +L+   N    +K   +  D
Sbjct: 5   NKTAVVTGAAGGIGQAIIRKLLAEGARVVA----ADLSADALKV-FNDFPADKLVTFSVD 59

Query: 222 VTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITST 380
           VTD +    ++     + G +D++INNA        L +D I  ++    VN   +    
Sbjct: 60  VTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGI 119

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
           L         + G  G ++N SSV A   S +   Y  +K+AV   + C       +  G
Sbjct: 120 LAGGRQF--QAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAAL--ELAPLG 175

Query: 561 VRVLTVCLGATDTALLTD-EKLGTFD 635
           VRV  V  G  DT +L   E LG ++
Sbjct: 176 VRVCAVAPGRVDTPMLRQYEALGLWE 201


>UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyces
           parvulus|Rep: Putative ketoreductase - Streptomyces
           parvulus
          Length = 265

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 58/201 (28%), Positives = 92/201 (45%), Gaps = 6/201 (2%)
 Frame = +3

Query: 24  MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 203
           MS E  D+V+ +TGA +GIG +  R+L+  G + + ++   E A     A L S +    
Sbjct: 1   MSLELTDRVMMVTGAGSGIGRAAARLLVGHGAR-VVLVGRTESALTETTAGLPSSH---H 56

Query: 204 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 383
                DV D++     +   V   G +D   NNA     S G   +    N   +I + L
Sbjct: 57  LVVPCDVGDDKQVADCVARAVSRFGRLDGAFNNAGTFG-SFGPLHQDTADNFDRVIATNL 115

Query: 384 KAI------EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 545
           + +      +I    + G GG ++N +SVA        P+Y ATK AV+  S  +     
Sbjct: 116 RGVWSCMRGQIEAMLTAG-GGAIVNCASVAGHIGHAQSPLYSATKHAVIGLSKSVAL--Q 172

Query: 546 FSKTGVRVLTVCLGATDTALL 608
           ++  G+RV  V  G+TDT +L
Sbjct: 173 YAGDGIRVNVVSPGSTDTPML 193


>UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Flavobacteriales bacterium HTCC2170
          Length = 245

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 54/196 (27%), Positives = 93/196 (47%), Gaps = 6/196 (3%)
 Frame = +3

Query: 39  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 218
           KDK+  +TG A GIG++V  +   EG   + I+D+  + GQ++ AE     G K +++  
Sbjct: 4   KDKIAVVTGGARGIGQAVSELFAKEGAT-VIIMDLLPQ-GQAV-AEGIIASGGKAEYHSL 60

Query: 219 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 380
            VT++    G+ ++V  + G ID++INNA +  D      S   +   IEVN+  +   T
Sbjct: 61  SVTNKSDVEGVFSSVNDKYGKIDILINNAGITRDRTLEKMSEAEWDAVIEVNLKGVFICT 120

Query: 381 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 560
              +  M      K G +++ +S   L  +     Y ATK+ V+  +        F K G
Sbjct: 121 QAVVPYM---KASKYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMAKT--WTVEFGKYG 175

Query: 561 VRVLTVCLGATDTALL 608
           +    +  G T T ++
Sbjct: 176 ITANAIAPGFTMTDMV 191


>UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain
           dehydrogenase/reductase SDR - Verminephrobacter eiseniae
           (strain EF01-2)
          Length = 261

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 49/194 (25%), Positives = 93/194 (47%), Gaps = 7/194 (3%)
 Frame = +3

Query: 45  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 224
           K   ITGAA GIG ++ + +  EG  H+ + DI++  G+   A+L +  G+   +   DV
Sbjct: 7   KTAVITGAADGIGHAIAQAMAREGA-HVFLSDISDAQGERCAAQLRAA-GHLADYLHCDV 64

Query: 225 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 383
              +    +++  V++ G +DV++NNAA+    + +       +++ IE+N+T++     
Sbjct: 65  AKADDIARLVDTAVRQTGHLDVMVNNAAIAIGGMPVHEMTDEQWQRLIEINLTSVFRGCK 124

Query: 384 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 563
            A+  M      K G++IN++S            Y   K AV+  +  +     F    +
Sbjct: 125 CALPHM---IAQKSGSIINMASAQGHIGLDGWTAYAGAKGAVMAMTRQMA--VEFGPVNI 179

Query: 564 RVLTVCLGATDTAL 605
           RV ++  G  DT +
Sbjct: 180 RVNSISPGTIDTPM 193


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 630,794,034
Number of Sequences: 1657284
Number of extensions: 12539209
Number of successful extensions: 44893
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 40596
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42256
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 50000004659
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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