Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV10l18r
(735 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=12... 171 2e-41
UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular org... 168 1e-40
UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|R... 161 2e-38
UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmi... 152 1e-35
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 144 2e-33
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 139 7e-32
UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium t... 138 1e-31
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 136 4e-31
UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Re... 128 1e-28
UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Re... 126 4e-28
UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=... 116 5e-25
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 116 5e-25
UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putativ... 115 1e-24
UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Re... 110 3e-23
UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium t... 109 7e-23
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 97 3e-19
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 97 4e-19
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 85 2e-15
UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella ve... 83 5e-15
UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomo... 81 4e-14
UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplas... 81 4e-14
UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1; ... 80 5e-14
UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18; Trichomonad... 80 6e-14
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 76 1e-12
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 72 2e-11
UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep: Zgc:1... 71 3e-11
UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella chej... 69 1e-10
UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;... 66 8e-10
UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;... 65 1e-09
UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21; Amniota|... 61 3e-08
UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD (so... 59 1e-07
UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to tetratrico... 55 2e-06
UniRef50_Q53TK9 Cluster: Malate dehydrogenase; n=3; Eutheria|Rep... 54 4e-06
UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate deh... 40 0.084
UniRef50_A0BUG0 Cluster: Chromosome undetermined scaffold_129, w... 38 0.26
UniRef50_A7RY18 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.4
UniRef50_Q0J1G4 Cluster: Os09g0441900 protein; n=2; Oryza sativa... 35 1.8
UniRef50_UPI0000DC2038 Cluster: UPI0000DC2038 related cluster; n... 35 2.4
UniRef50_UPI00006D0DE8 Cluster: Latrophilin/CL-1-like GPS domain... 34 3.1
UniRef50_Q54DK4 Cluster: Putative uncharacterized protein ak1; n... 34 3.1
UniRef50_O96695 Cluster: Rough deal protein; n=3; Sophophora|Rep... 34 3.1
UniRef50_Q0RYH4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_Q0U265 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
>UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=124;
cellular organisms|Rep: Malate dehydrogenase,
cytoplasmic - Homo sapiens (Human)
Length = 334
Score = 171 bits (416), Expect = 2e-41
Identities = 83/157 (52%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
V DVK VIIWGNHSSTQ+PD ++A + G + V E + DD++LKG FVTTVQ+RGA
Sbjct: 173 VTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGA 232
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVTV 380
AVI DH+RD WF E +VSMGV+SDG SYG P D++YSFPV +
Sbjct: 233 AVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVI 292
Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 269
N WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 293 KNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329
>UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular
organisms|Rep: Malate dehydrogenase - Oryza sativa
(Rice)
Length = 352
Score = 168 bits (408), Expect = 1e-40
Identities = 81/156 (51%), Positives = 98/156 (62%), Gaps = 1/156 (0%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
V V DVK IIWGNHSSTQFPDAS+A ++ V E+I D+ +L+ FVT VQ+RGA
Sbjct: 195 VHVGDVKNAIIWGNHSSTQFPDASHATVSTDRGERPVRELIADEIWLREEFVTDVQQRGA 254
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDVVYSFPVTVT 377
AVI DHMRDW LGT + WVSMGV SDGSYG P V +SFPVT
Sbjct: 255 AVIKARKQSSSLSAASAACDHMRDWILGTPKGTWVSMGVYSDGSYGVPEGVFFSFPVTCE 314
Query: 376 NGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 269
G+W +V+GL I DFAR ++ + EL EEK A +
Sbjct: 315 KGEWSVVQGLEIDDFARSKMETSATELKEEKSIAYE 350
>UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|Rep:
Malate dehydrogenase - Caenorhabditis elegans
Length = 336
Score = 161 bits (390), Expect = 2e-38
Identities = 72/158 (45%), Positives = 99/158 (62%), Gaps = 1/158 (0%)
Frame = -3
Query: 727 VKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 548
+ +VK VIIWGNHS TQFPD ++A G + + D+A+L+G F+ TVQKRG +
Sbjct: 176 IGNVKNVIIWGNHSGTQFPDVTHATVNKNGTETDAYAAVGDNAFLQGPFIATVQKRGGVI 235
Query: 547 IXXXXXXXXXXXXXXXSDHMRDWFLGTE-DRWVSMGVVSDGSYGTPRDVVYSFPVTVTNG 371
I DH+ DW GT+ ++VSM V SDGSYG P+ +++SFPVT+ G
Sbjct: 236 IEKRKLSSAMSAAKAACDHIHDWHFGTKAGQFVSMAVPSDGSYGIPQGLIFSFPVTIEGG 295
Query: 370 KWKIVEGLTISDFARQMLDATGKELVEEKQEALDVCKD 257
+WKIV+GL+ DFA+ + AT KEL EE+ +AL C D
Sbjct: 296 EWKIVQGLSFDDFAKGKIAATTKELEEERDDALKACDD 333
>UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase).; n=1;
Takifugu rubripes|Rep: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase). -
Takifugu rubripes
Length = 382
Score = 152 bits (368), Expect = 1e-35
Identities = 76/157 (48%), Positives = 101/157 (64%), Gaps = 3/157 (1%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
VP VK VIIWGNHSSTQ+PD + + + G++ + + I D+A+LKG F+ TVQ+RGA
Sbjct: 222 VPATHVKNVIIWGNHSSTQYPDVHHCMVNMSGSELTCFDAIKDEAWLKGEFIATVQQRGA 281
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDG-SYGTPRDVVYSFPVTV 380
AVI DHMRD + GT E ++SMGV S G SYG P D++YSFPV +
Sbjct: 282 AVIKARKLSSAMSAAKAICDHMRDIWTGTPEGEFISMGVYSTGNSYGVPDDLIYSFPVQI 341
Query: 379 TNGK-WKIVEGLTISDFARQMLDATGKELVEEKQEAL 272
K WKIV+GL I+ F++ +DAT EL+EE+ AL
Sbjct: 342 HKDKSWKIVDGLGINSFSQTKMDATAAELMEERDTAL 378
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 144 bits (350), Expect = 2e-33
Identities = 66/152 (43%), Positives = 98/152 (64%), Gaps = 1/152 (0%)
Frame = -3
Query: 727 VKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 548
+ DVK VIIWGNHS+TQ+PD ++ ++G K + + IND+AYL AF+ VQKRG V
Sbjct: 215 ITDVKNVIIWGNHSTTQYPDVNHGT-VLG---KRIRQFINDEAYLNNAFIERVQKRGGEV 270
Query: 547 IXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNG 371
+ DH+ DW+ GT+ +VSM V SDGSYG P+ +++S+PVT +N
Sbjct: 271 LAARKNSSVMSAANAVKDHLHDWYFGTKSGEFVSMAVYSDGSYGVPKGLIFSYPVTCSNF 330
Query: 370 KWKIVEGLTISDFARQMLDATGKELVEEKQEA 275
+KIV+GL I +F+++ + T +EL+ EK +A
Sbjct: 331 NYKIVQGLNIDEFSKEKIRITTEELLSEKADA 362
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 139 bits (336), Expect = 7e-32
Identities = 68/148 (45%), Positives = 90/148 (60%)
Frame = -3
Query: 727 VKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 548
V D+K++ +WGNHS T + D A V G KSV + IND A+ K F+ TV KRGAA+
Sbjct: 178 VGDIKKLTVWGNHSPTMYADYR--FATVDG--KSVKDAINDPAWYKDVFLPTVGKRGAAI 233
Query: 547 IXXXXXXXXXXXXXXXSDHMRDWFLGTEDRWVSMGVVSDGSYGTPRDVVYSFPVTVTNGK 368
I DHMRDW LG++ WV+MGV S+G YG P +V+ FPVT NG+
Sbjct: 234 IAARGLSSAASAANAAIDHMRDWALGSKGEWVTMGVPSNGEYGIPAGIVFGFPVTTENGE 293
Query: 367 WKIVEGLTISDFARQMLDATGKELVEEK 284
+KIVEGL I F+++ +D T EL E+
Sbjct: 294 YKIVEGLPIDAFSQECIDKTLAELQGEQ 321
>UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 356
Score = 138 bits (335), Expect = 1e-31
Identities = 69/156 (44%), Positives = 93/156 (59%), Gaps = 2/156 (1%)
Frame = -3
Query: 727 VKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 548
V+DV+ +IIWGNHS+TQF D S A G ++V ++ DDA+L+ AFV V KRG A+
Sbjct: 197 VEDVRNIIIWGNHSTTQFADVSQATVQQNGISQTVRGLVADDAWLQKAFVEQVAKRGGAI 256
Query: 547 IXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGS-YGTPRDVVYSFPVTVTN 374
I DH+ DW +GT++ +VSMGVV+DG YG V +SFP +
Sbjct: 257 IEKRKASSAASAASAVCDHIHDWLIGTDNGTFVSMGVVTDGKLYGIKEQVCFSFPCICKD 316
Query: 373 GKWKIVEGLTISDFARQMLDATGKELVEEKQEALDV 266
G K+VEGL F + M+D T KEL+EEK+ A V
Sbjct: 317 GNVKVVEGLKWDQFQQSMIDKTLKELLEEKEMAFSV 352
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 136 bits (330), Expect = 4e-31
Identities = 69/154 (44%), Positives = 92/154 (59%), Gaps = 5/154 (3%)
Frame = -3
Query: 730 PVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIIN-----DDAYLKGAFVTTVQ 566
PV K+V +WGNHS T +PD A A GA+ V E++ DA+ K F+ TV
Sbjct: 179 PVASFKKVAVWGNHSPTMYPDVRFATA--DGAK--VPELLKLGTAEGDAWNKDTFIPTVG 234
Query: 565 KRGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTEDRWVSMGVVSDGSYGTPRDVVYSFPV 386
KRGAA+I DH+RDW+LGT WV+MG+ SDGSY P ++Y FPV
Sbjct: 235 KRGAAIIEARGLSSAASAASAAVDHIRDWWLGTNGEWVTMGIPSDGSYDIPEGIMYGFPV 294
Query: 385 TVTNGKWKIVEGLTISDFARQMLDATGKELVEEK 284
T NG+++IV+GL I F+R+ ++ T KEL EEK
Sbjct: 295 TCKNGEYEIVKGLEIDAFSREKMNNTLKELNEEK 328
>UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Rep:
Malate dehydrogenase - Trypanosoma cruzi
Length = 332
Score = 128 bits (309), Expect = 1e-28
Identities = 72/156 (46%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = -3
Query: 727 VKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 548
V+DVK IIWGNHS TQ PD ++A V G V E I DDAYL G F+TTVQ+RG +
Sbjct: 179 VRDVKNCIIWGNHSGTQVPDVNSAT--VKGVP--VREAIKDDAYLDGEFMTTVQQRGYEI 234
Query: 547 IXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGS-YGTPRDVVYSFPVTVTN 374
I D + DW LGT VSM V SDG+ YG P +V+SFPVT +
Sbjct: 235 IRWRGNSSALSAANAAVDQVHDWVLGTPTGTHVSMAVYSDGNPYGVPPGLVFSFPVTCSG 294
Query: 373 GKWKIVEGLTISDFARQMLDATGKELVEEKQEALDV 266
G+W VE I+ + L AT KEL EE+ E+L +
Sbjct: 295 GEWHFVENACITPSVAKHLAATTKELEEERAESLSL 330
>UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Rep:
Malate dehydrogenase - Frankia sp. (strain CcI3)
Length = 329
Score = 126 bits (305), Expect = 4e-28
Identities = 60/152 (39%), Positives = 91/152 (59%), Gaps = 1/152 (0%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
VP ++K++ IWGNHS+TQ+PD +A VGG +S +E + D A++ F+ V KRGA
Sbjct: 174 VPSAEIKKITIWGNHSATQYPDIFHAE--VGG--RSGAEAVGDQAWIADEFIPRVAKRGA 229
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGTE-DRWVSMGVVSDGSYGTPRDVVYSFPVTVT 377
+I DH+ W GT W S + SDGSYG P ++ SFPVT +
Sbjct: 230 EIIEVRGASSAASAASAAIDHIFTWVNGTPAGDWTSAAIPSDGSYGVPEGLISSFPVTAS 289
Query: 376 NGKWKIVEGLTISDFARQMLDATGKELVEEKQ 281
G+++IV+GL + F+R+ +DA+ +EL EE++
Sbjct: 290 GGRFEIVQGLELDAFSREKIDASVRELAEERE 321
>UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=2;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 1 - Entamoeba histolytica
Length = 355
Score = 116 bits (280), Expect = 5e-25
Identities = 59/150 (39%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = -3
Query: 727 VKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 548
V+DV +WGNHS Q PD S+AV K V++++ ++++L+ +F TVQ+RGA V
Sbjct: 192 VEDVSDAFVWGNHSEKQCPDISHAVVQTPNGPKRVADLV-EESWLE-SFNKTVQERGAKV 249
Query: 547 IXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDVVYSFPVTVTNG 371
I DH RDW LGT +++ V MGV S+G YG P+ + +S PV G
Sbjct: 250 IEMRKASSAASAAKAIVDHFRDWCLGTNKEKIVCMGVYSEGQYGIPKGIFFSMPVVCYGG 309
Query: 370 KWKIVEGLTISDFARQMLDATGKELVEEKQ 281
++ IV+ L +S+ R ML + +EL+EEK+
Sbjct: 310 EYHIVDDLVLSESTRTMLKNSEEELLEEKK 339
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 116 bits (280), Expect = 5e-25
Identities = 57/151 (37%), Positives = 90/151 (59%), Gaps = 2/151 (1%)
Frame = -3
Query: 727 VKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 548
+ +K+VIIWGNHS TQ+PD ++ +I+ G K SE + D +L+ A + VQ+RG +
Sbjct: 177 IDQIKKVIIWGNHSLTQYPDMTH--SIING--KQASETFSKD-FLRNALIQQVQQRGGQI 231
Query: 547 IXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGS-YGTPRDVVYSFPVTVTN 374
+ DH+R WFLGT +D W S GV+SDG+ YG P+ + +S PVT
Sbjct: 232 LQLSRGASTISGAIAVKDHLRTWFLGTSQDNWTSFGVISDGNHYGIPKGICFSLPVTCKE 291
Query: 373 GKWKIVEGLTISDFARQMLDATGKELVEEKQ 281
++K+V + + DF++Q + + EL +E+Q
Sbjct: 292 FEFKVVGDVELDDFSKQRIQLSLVELQKEQQ 322
>UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putative;
n=7; Eukaryota|Rep: Cytosolic malate dehydrogenase,
putative - Leishmania major
Length = 324
Score = 115 bits (276), Expect = 1e-24
Identities = 67/155 (43%), Positives = 83/155 (53%), Gaps = 2/155 (1%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
VPV V+ VIIWGNHSSTQ PD +AV +G E I DDA L FV V+ RGA
Sbjct: 173 VPVSQVRNVIIWGNHSSTQVPDTDSAV--IG--TTPAREAIKDDA-LDDDFVQVVRGRGA 227
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSD-GSYGTPRDVVYSFPVTV 380
+I DH+ DW GT E +VSMGV SD YG P +++SFP T
Sbjct: 228 EIIQLRGLSSAMSAAKAAVDHVHDWIHGTPEGVYVSMGVYSDENPYGVPSGLIFSFPCTC 287
Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEA 275
G+W +V G D +Q L +T EL EE+ +A
Sbjct: 288 HAGEWTVVSGKLNGDLGKQRLASTIAELQEERAQA 322
>UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Rep:
Malate dehydrogenase - Mastigamoeba balamuthi
(Phreatamoeba balamuthi)
Length = 382
Score = 110 bits (265), Expect = 3e-23
Identities = 61/158 (38%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAI---VGGAQKSVSEIINDDAYLKGAFVTTVQK 563
V ++V I+WGNHS TQ+PD A GA +INDD ++ FV TVQ+
Sbjct: 217 VETRNVHNAIVWGNHSGTQYPDLRFARVDDFPTKGASTPARALINDDEWVFKTFVPTVQQ 276
Query: 562 RGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGS-YGTPRDVVYSFP 389
RG VI D +RDW LGT VSMGVV+DGS YG D+V+S P
Sbjct: 277 RGYKVIEARKLSSAASAATAACDAIRDWVLGTPAGEMVSMGVVTDGSKYGIAEDLVFSMP 336
Query: 388 VTVTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEA 275
V + G++ +V+ L + +++ L A+ +EL+ E+ EA
Sbjct: 337 VQCSGGEYTVVDNLPVDAESQRRLRASEQELIAERTEA 374
>UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 360
Score = 109 bits (262), Expect = 7e-23
Identities = 58/151 (38%), Positives = 84/151 (55%), Gaps = 1/151 (0%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
V D++++ I+GNHS T P A K+ + D ++ F+ TVQ+RGA
Sbjct: 209 VHTSDIRKIAIFGNHSPTMVPYIDQMTA------KNHKATV-DQQWVTQTFIPTVQQRGA 261
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDVVYSFPVTVT 377
+I +H+ W GT E + SM + SDGSYG P+ +++SFPVTV
Sbjct: 262 EIIKARKLSSAASAGNAAMNHITTWVNGTAEGDYTSMAIPSDGSYGVPKGLIFSFPVTVK 321
Query: 376 NGKWKIVEGLTISDFARQMLDATGKELVEEK 284
NGK+ IV+GL IS F + +LD T KELV+E+
Sbjct: 322 NGKYSIVQGLPISPFYQGLLDKTIKELVDER 352
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 97.5 bits (232), Expect = 3e-19
Identities = 54/152 (35%), Positives = 80/152 (52%), Gaps = 2/152 (1%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
VP+++V RV+IWGNHS+ Q PD + A I G K +E+I D +L+ V +VQ RG+
Sbjct: 175 VPLEEVSRVVIWGNHSAKQVPDFTQA-RISG---KPAAEVIGDRDWLENILVHSVQNRGS 230
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGTEDRWVSMGVVSD-GSYGTPRDVVYSFPV-TV 380
AVI ++ R F D W S GV SD YG P D+++ FP +
Sbjct: 231 AVIEARGKSSAASASRALAEAARSIFCPKSDEWFSSGVCSDHNPYGIPEDLIFGFPCRML 290
Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEK 284
+G ++I+ GL F R + + E+ +EK
Sbjct: 291 PSGDYEIIPGLPWEPFIRNKIQISLDEIAQEK 322
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 97.1 bits (231), Expect = 4e-19
Identities = 56/159 (35%), Positives = 84/159 (52%), Gaps = 3/159 (1%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
V + V VI+WGNHS+TQ PDA +A + V++ + D YL+ F + RG
Sbjct: 154 VTPEKVHNVIVWGNHSNTQVPDAYHATVDLPEGTVKVADKL-DAEYLEKEFAPMIATRGG 212
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGV-VSDGS-YGTPRDVVYSFPVT 383
AVI ++DW GT+D +VSM + V D YG + ++YSFP T
Sbjct: 213 AVIKMRGASSAASAANAALTCVKDWIYGTKDGEFVSMAIPVPDNEPYGVKQGIIYSFPCT 272
Query: 382 VTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALDV 266
+G+ K+VE L +++ + + AT +ELV EK+ A V
Sbjct: 273 CKDGEVKVVENLERNEWVKSKMVATEQELVGEKETAWKV 311
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 85.0 bits (201), Expect = 2e-15
Identities = 49/146 (33%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXX 539
V +I+WGNHS+T PD S + K ++ I D AF V+ RG VI
Sbjct: 184 VHNIIVWGNHSNTMQPDLSYSYLADQNGIKPLANCIEDF----DAFTEKVRCRGEEVIST 239
Query: 538 XXXXXXXXXXXXXSDHMRDWFLGTEDR-WVSMGVVSDGSYGTPRDVVYSFPVTVTNGKWK 362
H++DW GT+ VSMGV S+G YG + YS PVT + G++
Sbjct: 240 RKASSAGSAAHAICQHIKDWIYGTKPGIMVSMGVSSNGEYGIDTGLFYSMPVTCSEGEYH 299
Query: 361 IVEGLTISDFARQMLDATGKELVEEK 284
IV+ L I + L + EL++E+
Sbjct: 300 IVDSLVIEPRIKDSLILSELELIDER 325
>UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 462
Score = 83.4 bits (197), Expect = 5e-15
Identities = 51/160 (31%), Positives = 80/160 (50%), Gaps = 11/160 (6%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAV------AIVG----GAQKSVSEIINDDAYLKGAFVTTV 569
+K +I+WGN +PDAS+A AI G G + V E+++D+ +L G FV +
Sbjct: 305 IKDLIVWGNPGFNHYPDASHARVDGFDGAIWGPHVPGFTRPVPEMVHDNKWLSGEFVEVL 364
Query: 568 QKRGAAVIXXXXXXXXXXXXXXXSDHMRDWF-LGTEDRWVSMGVVSDGSYGTPRDVVYSF 392
+K ++DW + D W S+GV+S+G Y P + +SF
Sbjct: 365 KKPSEG-------ENALMGSVAVKSLLQDWCQCASSDMW-SLGVISEGWYDIPEGIAFSF 416
Query: 391 PVTVTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEAL 272
PV T G W++VEGL +SD +++L +E E +E L
Sbjct: 417 PVKFTGGSWQVVEGLALSDSLKEVLKNIAQEAKAETEEVL 456
>UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomonas
acosta|Rep: Malate dehydrogenase - Hypotrichomonas
acosta
Length = 318
Score = 80.6 bits (190), Expect = 4e-14
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 6/160 (3%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAI--VGGAQKSVSEIINDDAYLKGAFVTTVQKR 560
VP+ V V +WGNH+ TQ PD ++ G +K+ E+ + + F+ + +R
Sbjct: 153 VPIDHVYHVAVWGNHAETQVPDITHVEVTDENGTHRKAFDELCRIEP--EPDFIEVIAQR 210
Query: 559 GAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTE-DRWVSMGV-VSDG-SYGTPRDVVYSFP 389
V+ HMR W GT + W+S+G+ V +G SYG +++SFP
Sbjct: 211 AWKVLEMRGKTSAGSAVNAALCHMRAWLFGTRPNDWISLGIPVPEGNSYGIKPGIIFSFP 270
Query: 388 VTV-TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEAL 272
TV GK IVE L ++ + + T K+L EE++ AL
Sbjct: 271 CTVDEKGKVHIVENLELNPEIKTKIAQTEKDLFEERETAL 310
>UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplast
precursor; n=62; cellular organisms|Rep: Malate
dehydrogenase [NADP], chloroplast precursor - Zea mays
(Maize)
Length = 432
Score = 80.6 bits (190), Expect = 4e-14
Identities = 51/149 (34%), Positives = 74/149 (49%), Gaps = 3/149 (2%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXX 539
V V IWGNHS+TQ PD NA I G + V E+I D +L+ F TVQKRG +I
Sbjct: 263 VSNVTIWGNHSTTQVPDFLNA-KIDG---RPVKEVIKDTKWLEEEFTLTVQKRGGVLIQK 318
Query: 538 XXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGS-YGTPRDVVYSFPV-TVTNGK 368
D +R T E W S GV + G+ YG D+V+S P + +G
Sbjct: 319 WGRSSAASTAVSIVDAIRSLVTPTPEGDWFSTGVYTTGNPYGIAEDIVFSMPCRSKGDGD 378
Query: 367 WKIVEGLTISDFARQMLDATGKELVEEKQ 281
+++ + + DF + + + EL+ EK+
Sbjct: 379 YELASDVLMDDFLWERIKKSEAELLAEKK 407
>UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1;
Branchiostoma floridae|Rep: Putative uncharacterized
protein - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 522
Score = 80.2 bits (189), Expect = 5e-14
Identities = 49/151 (32%), Positives = 76/151 (50%), Gaps = 9/151 (5%)
Frame = -3
Query: 709 VIIWGNHSSTQFPDASNAV------AIVGGAQKS--VSEIINDDAYLKGAFVTTVQKRGA 554
VI+WGN T + D S A AI G S VSE+++D+ +L+G F+ +Q R
Sbjct: 308 VIVWGNVGGTTYTDVSRARVHGYDGAIWGPPSYSCSVSEMVHDNKWLEGEFLEQLQSRSH 367
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDVVYSFPVTVT 377
+ S + W+ G+ E + S+ V S+G Y P VV+SFPV
Sbjct: 368 TIQDSLQHSADLSMAAAISSTLSYWWNGSPEGQLFSLAVCSEGFYNIPEGVVFSFPVMFH 427
Query: 376 NGKWKIVEGLTISDFARQMLDATGKELVEEK 284
G W++V+ + +++ R ML + +LVEEK
Sbjct: 428 KGSWEVVQDIDMNEDMRVMLSSITAQLVEEK 458
>UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18;
Trichomonadinae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 339
Score = 79.8 bits (188), Expect = 6e-14
Identities = 47/158 (29%), Positives = 76/158 (48%), Gaps = 4/158 (2%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
V V D+ +++WGNH + D + A G + V++++ D+ Y + F + RG
Sbjct: 172 VKVTDLHDIVVWGNHGESMVADLTQATFEKDGKIQKVTDVL-DEKYREETFFKFISHRGW 230
Query: 553 AVIXXXXXXXXXXXXXXXSDHMRDWFLGTEDRWV-SMG--VVSDGSYGTPRDVVYSFPVT 383
++ HM+ W GT+ V SMG V + YG VV+S P T
Sbjct: 231 DIVEYRGFSSAASPTKASIQHMKAWLFGTKPGEVLSMGIPVPENNKYGLKPGVVFSLPCT 290
Query: 382 V-TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEAL 272
V +G +VE ++D+ R+ L+ T K+L EK+ AL
Sbjct: 291 VDKDGNVHVVETYKVNDWLREKLEFTEKDLFNEKEIAL 328
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 75.8 bits (178), Expect = 1e-12
Identities = 51/157 (32%), Positives = 78/157 (49%), Gaps = 4/157 (2%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXX 539
V +V+IWGN SS+Q PD SNA + + E ++++ Y+ F + + +RG V
Sbjct: 177 VYKVVIWGNRSSSQIPDVSNAEYQDETGRHHILEKVSEE-YVNTEFSSDLAQRGNKVTMM 235
Query: 538 XXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGV-VSDGS-YGTPRDVVYSFPVTV-TNG 371
MRDW GT D +VSM V V + S YG + +SFP TV G
Sbjct: 236 RGASSAASAATAAIQCMRDWLYGTPADNFVSMSVPVPESSPYGVKPGIFFSFPCTVDKEG 295
Query: 370 KWKIVEGLTISDFARQMLDATGKELVEEKQEALDVCK 260
+VEGL + +AT K++ ++++E L+ K
Sbjct: 296 NIHVVEGLPVD-------EATAKKIKQQEEEILNELK 325
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 71.7 bits (168), Expect = 2e-11
Identities = 49/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAVAIVGGAQ--KSVSEIINDDAYLKGAFVTTVQKRGAAVI 545
+ V + GNHS+T P V G + + V ++ D ++KG FV V+ RG AVI
Sbjct: 179 ISNVWVAGNHSNTMVPIVDCGVIYDEGLKDKQPVKPMLPAD-WIKGEFVPCVRGRGTAVI 237
Query: 544 XXXXXXXXXXXXXXXSDHMRDWFLGTE-DRWVSMG-VVSDGS-YGTPRDVVYSFPVTVTN 374
DH+RDW +GT+ +VS ++ +G+ YG + YS P +
Sbjct: 238 EARGHSSSASAANAAIDHVRDWHMGTKPGAFVSCSLLIEEGNPYGIAPGIFYSMPCSCVG 297
Query: 373 GKWKIVEGLTISDFARQMLDATGKELVEEKQEALDVCK 260
GKW+IV+ D + +LD E +EA D K
Sbjct: 298 GKWQIVK----LDLPKDVLDEMKLSEAELMKEAADALK 331
>UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep:
Zgc:153922 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 447
Score = 70.9 bits (166), Expect = 3e-11
Identities = 50/168 (29%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Frame = -3
Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAV------AIVG--GAQKSVSEIINDDAYLKGAFV 578
V D+ VI+WGN S + D A AI G G + V E+I D +LK F
Sbjct: 278 VKTSDITNVIVWGNISGSFHIDLQRAKVFRYDGAIRGPDGFSQHVMEMIYDWKWLKTDFR 337
Query: 577 TTVQKRGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTEDRWV-SMGVVSDGSYGTPRDVV 401
+ + K A + ++ W V S+GV+S G +G P +V
Sbjct: 338 SLLHKHRATISSKTNKATAISTTNAILAILKAWNNAESPEEVFSLGVLSTGQFGIPAGLV 397
Query: 400 YSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALDVCKD 257
+S PV+ T+G W + +T++D R LDA EL E+ A K+
Sbjct: 398 FSMPVSFTDGHWSVRSDVTVTDELRVNLDACADELRMERDMAAKTLKN 445
>UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella
chejuensis KCTC 2396|Rep: Malate dehydrogenase - Hahella
chejuensis (strain KCTC 2396)
Length = 193
Score = 68.9 bits (161), Expect = 1e-10
Identities = 41/106 (38%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXX 539
+KR+ IWGNH+ST FPDAS+ + I G + D + + + VQ+RG AVI
Sbjct: 83 IKRLTIWGNHASTLFPDASH-LRIDG----QPIRMALDMNWYRDIMIDQVQQRGTAVISC 137
Query: 538 XXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGSYGTPRDV 404
DH+RDW GTE+ +VSMGV+S G DV
Sbjct: 138 KGRTSSSSAAQAIIDHLRDWRFGTEEGDFVSMGVLSQGDRKPVADV 183
>UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 553
Score = 66.1 bits (154), Expect = 8e-10
Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAV------AIVGGAQKS--VSEIINDDAYLKGAFVTTVQK 563
V +IIWGN D S A AI G + S V+E+++D+ +L+ + +Q
Sbjct: 302 VADLIIWGNIGGITHFDISQARVYKYEGAIWGPSSFSRPVTEVVHDEKWLQTEYPQLLQN 361
Query: 562 RGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTEDRWV-SMGVVSDGSYGTPRDVVYSFPV 386
A+ + + W+ G+ D+ + S+GV SDG Y P D+ +S PV
Sbjct: 362 HPDALATMLNHKVAMSEAHALTSILTHWYNGSPDKEIFSLGVYSDGWYDLPVDIFFSLPV 421
Query: 385 TVTNGKWKIVEGLTISDFARQMLDATGKELVEEK 284
G W++V+ ++ R LD EL+ E+
Sbjct: 422 KFQKGAWEVVQDRQVTTEIRAQLDQITNELIHER 455
>UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG5362-PA - Nasonia vitripennis
Length = 358
Score = 65.3 bits (152), Expect = 1e-09
Identities = 47/155 (30%), Positives = 70/155 (45%), Gaps = 1/155 (0%)
Frame = -3
Query: 721 DVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIX 542
DVK +IIWG +S + FP +A +KSV I DD + K T+ K V
Sbjct: 192 DVKNLIIWGTNSRSVFPYCGHAKF---SDEKSVINEICDDKWFK----KTLPKLVEGVFR 244
Query: 541 XXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNGKW 365
+H + GT W M VVSDGSY +SFP+ +G W
Sbjct: 245 KCRYRISEALALA--EHCKLLVQGTPPGEWTCMSVVSDGSYDVTPGHFFSFPLYCRDGNW 302
Query: 364 KIVEGLTISDFARQMLDATGKELVEEKQEALDVCK 260
+IV L + D+ ++++ L E+ + AL +C+
Sbjct: 303 EIVRDLYVEDYCKRIIKDIIVALDEKIEAALKICR 337
>UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21;
Amniota|Rep: Malate dehydrogenase 1B - Homo sapiens
(Human)
Length = 518
Score = 60.9 bits (141), Expect = 3e-08
Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 9/158 (5%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNA------VAIVGGAQKS--VSEIINDDAYLKGAFVTTVQK 563
+K VIIWGN S + D AI G S V +I D ++K FV ++
Sbjct: 305 IKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNLIFDSEWVKREFVAILKN 364
Query: 562 RGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPV 386
+ + ++ W+ G+ VS+G++S+G +G P+ +V+S PV
Sbjct: 365 ----LTTTGRQFGGILAAHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPV 420
Query: 385 TVTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEAL 272
NG W ++ L + + Q++ +L++EK AL
Sbjct: 421 KFENGTWVVLTDLKDVEISEQIMTRMTSDLIQEKLVAL 458
>UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD
(soluble); n=1; Takifugu rubripes|Rep: malate
dehydrogenase 1B, NAD (soluble) - Takifugu rubripes
Length = 441
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 9/136 (6%)
Frame = -3
Query: 721 DVKRVIIWGNHSSTQFPDASNA-VAIVGGAQKS-------VSEIINDDAYLKGAFVTTVQ 566
DV+ VI+WGN S + + D V G K IIND +++ F V+
Sbjct: 297 DVRDVIVWGNISGSFYVDLQKTKVFNYDGPVKGPEFFSLPAQNIINDRTWIETDFQELVR 356
Query: 565 KRGAAVIXXXXXXXXXXXXXXXSDHMRDWF-LGTEDRWVSMGVVSDGSYGTPRDVVYSFP 389
R AAV+ ++ W LG + S+GV+ G + P VV S P
Sbjct: 357 SRRAAVVSRMNRTTAMSCSHGILTVLKAWNGLGAGNEVFSLGVLCSGYHDLPDGVVLSVP 416
Query: 388 VTVTNGKWKIVEGLTI 341
+T T+GKW + +TI
Sbjct: 417 LTFTDGKWSALSDVTI 432
>UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to
tetratricopeptide repeat domain 21B; n=1; Apis
mellifera|Rep: PREDICTED: similar to tetratricopeptide
repeat domain 21B - Apis mellifera
Length = 1491
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Frame = -3
Query: 721 DVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEI-INDDAYLKGAFVTTVQKRGAAVI 545
+VK +IIWG++ S FPD G K +I I +D + + R +
Sbjct: 1342 EVKNIIIWGSNGSYCFPDCRYLYLTNGKPLKDSIKIWIYNDL---PRIIRSTYNRACLI- 1397
Query: 544 XXXXXXXXXXXXXXXSDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDVVYSFPVTVTNGK 368
++H + + GT E+ W SMGV+SD SY + +SFPV + +
Sbjct: 1398 --------NSIAYALAEHCKILWNGTPENEWTSMGVLSDLSYSIQSGIFFSFPVICKDKQ 1449
Query: 367 WKIVEGLTISDFARQMLDATGKELVEEKQEALDVC 263
+I++ + ++ ++ + + + E Q AL++C
Sbjct: 1450 CEIIKDFELDEYVKKYIVDLSRLIFREIQIALEIC 1484
>UniRef50_Q53TK9 Cluster: Malate dehydrogenase; n=3; Eutheria|Rep:
Malate dehydrogenase - Homo sapiens (Human)
Length = 283
Score = 54.0 bits (124), Expect = 4e-06
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
Frame = -3
Query: 490 MRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLD 314
++ W+ G+ VS+G++S+G +G P+ +V+S PV NG W ++ L + + Q++
Sbjct: 172 LKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFENGTWVVLTDLKDVEISEQIMT 231
Query: 313 ATGKELVEEKQEAL 272
+L++EK AL
Sbjct: 232 RMTSDLIQEKLVAL 245
>UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate
dehydrogenase 1B, NAD (soluble); n=1; Monodelphis
domestica|Rep: PREDICTED: similar to Malate
dehydrogenase 1B, NAD (soluble) - Monodelphis domestica
Length = 655
Score = 39.5 bits (88), Expect = 0.084
Identities = 37/154 (24%), Positives = 64/154 (41%), Gaps = 9/154 (5%)
Frame = -3
Query: 718 VKRVIIWGNHSSTQFPDASNAV------AIVGGAQKS--VSEIINDDAYLKGAFVTTVQK 563
VK VIIWGN + ++ D A AI G S + ++I D +++ FV ++
Sbjct: 440 VKDVIIWGNITGFRYIDLKKAKIFKYNSAIWGPPNYSRFLLQLIFDSEWIRKEFVASLN- 498
Query: 562 RGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPV 386
A + + WF + + S+G+ S+G +G P +V S P
Sbjct: 499 ---AWSLKEHFQKAIPSAHCIATMLTFWFHDSPPGEFFSVGIRSEGEFGMPEGMVISMPA 555
Query: 385 TVTNGKWKIVEGLTISDFARQMLDATGKELVEEK 284
NG W + L S+ + + +L +E+
Sbjct: 556 QCQNGIWTVPTDLIESELTEDVRNRIIHDLQQEQ 589
>UniRef50_A0BUG0 Cluster: Chromosome undetermined scaffold_129,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_129,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 283
Score = 37.9 bits (84), Expect = 0.26
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = -3
Query: 370 KWKIVEGLTISDFARQMLDATGKELVEEKQEALDV 266
K K+VEGL + F + M+D T KEL+EEK+ A V
Sbjct: 7 KVKVVEGLKLDQFLQCMIDKTLKELLEEKEMAFSV 41
>UniRef50_A7RY18 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 150
Score = 35.5 bits (78), Expect = 1.4
Identities = 19/56 (33%), Positives = 21/56 (37%)
Frame = -2
Query: 668 CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSFCC*SC 501
C ECC + C K C C + IC CC CC IC CC C
Sbjct: 52 CIECCYMLFFCYKCCI-----ECCYMLFICYK-----CCIECCYMLFICYKCCIEC 97
Score = 35.5 bits (78), Expect = 1.4
Identities = 19/56 (33%), Positives = 21/56 (37%)
Frame = -2
Query: 668 CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSFCC*SC 501
C ECC + C K C C + IC CC CC IC CC C
Sbjct: 94 CIECCYMLFFCYKCCI-----ECCYMLFICYK-----CCIECCYMLFICYKCCIEC 139
Score = 33.9 bits (74), Expect = 4.2
Identities = 18/56 (32%), Positives = 20/56 (35%)
Frame = -2
Query: 668 CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSFCC*SC 501
C ECC + C K C C + IC CC CC C CC C
Sbjct: 10 CIECCYLLFFCYKCCI-----ECCYMLFICYK-----CCIECCYMLFFCYKCCIEC 55
Score = 33.9 bits (74), Expect = 4.2
Identities = 18/56 (32%), Positives = 20/56 (35%)
Frame = -2
Query: 668 CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSFCC*SC 501
C ECC + C K C C + C CC CC IC CC C
Sbjct: 38 CIECCYMLFFCYKCCI-----ECCYMLFFCYK-----CCIECCYMLFICYKCCIEC 83
Score = 33.9 bits (74), Expect = 4.2
Identities = 18/56 (32%), Positives = 20/56 (35%)
Frame = -2
Query: 668 CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSFCC*SC 501
C ECC + C K C C + C CC CC IC CC C
Sbjct: 80 CIECCYMLFICYKCCI-----ECCYMLFFCYK-----CCIECCYMLFICYKCCIEC 125
>UniRef50_Q0J1G4 Cluster: Os09g0441900 protein; n=2; Oryza sativa
(japonica cultivar-group)|Rep: Os09g0441900 protein -
Oryza sativa subsp. japonica (Rice)
Length = 444
Score = 35.1 bits (77), Expect = 1.8
Identities = 23/61 (37%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Frame = -2
Query: 668 CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCC-RYCCQENVICSFCC-*SCIR 495
C C YC +CS C +R C N S + CC CC+ N CS CC SC
Sbjct: 117 CISCLCYCCKCSPKC----------KRPRCLNCSCSSCCDEPCCKPN--CSACCAGSCCS 164
Query: 494 P 492
P
Sbjct: 165 P 165
>UniRef50_UPI0000DC2038 Cluster: UPI0000DC2038 related cluster; n=1;
Rattus norvegicus|Rep: UPI0000DC2038 UniRef100 entry -
Rattus norvegicus
Length = 184
Score = 34.7 bits (76), Expect = 2.4
Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 11/64 (17%)
Frame = -2
Query: 668 CFECCSYCW----RCSKICF*NYQ*RCI---FERRICNNGSKTWCCRYCCQENV----IC 522
C CC YC CS C Q +CI C NG+ CC CC N +C
Sbjct: 70 CHCCCCYCCCAPVACSSECCQPVQCQCIQVSCAGSYCVNGNCCCCC--CCFPNYRPDCLC 127
Query: 521 SFCC 510
S+CC
Sbjct: 128 SYCC 131
>UniRef50_UPI00006D0DE8 Cluster: Latrophilin/CL-1-like GPS domain
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Latrophilin/CL-1-like GPS domain containing
protein - Tetrahymena thermophila SB210
Length = 5230
Score = 34.3 bits (75), Expect = 3.1
Identities = 15/22 (68%), Positives = 16/22 (72%), Gaps = 1/22 (4%)
Frame = +1
Query: 442 LPC*PICLQC-QGTNLSCGLMQ 504
LPC P+CLQC TNLSC L Q
Sbjct: 2873 LPCNPLCLQCTDQTNLSCSLCQ 2894
>UniRef50_Q54DK4 Cluster: Putative uncharacterized protein ak1; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein ak1 - Dictyostelium discoideum
AX4
Length = 1352
Score = 34.3 bits (75), Expect = 3.1
Identities = 22/65 (33%), Positives = 29/65 (44%)
Frame = +1
Query: 403 QHHAEYHKIHLKQLPC*PICLQCQGTNLSCGLMQL*QQKEQMTFSWQQ*RQHHVFEPLLQ 582
QHH+ K+HL +P LQ Q L L Q QQ++Q QQ +Q + P
Sbjct: 378 QHHSSDFKVHLIDIPTTQQQLQQQQLQLQQQLQQQLQQQQQQQQQQQQQQQSPISNPFTS 437
Query: 583 MRLSN 597
SN
Sbjct: 438 NNNSN 442
>UniRef50_O96695 Cluster: Rough deal protein; n=3; Sophophora|Rep:
Rough deal protein - Drosophila melanogaster (Fruit fly)
Length = 2098
Score = 34.3 bits (75), Expect = 3.1
Identities = 18/41 (43%), Positives = 27/41 (65%), Gaps = 4/41 (9%)
Frame = +1
Query: 76 YKNKNIDKSFN----NNAF*PAMIRLIPKKNNINKLLLPIY 186
YK+KN +S++ NNAF +++RL+ K NN NK L +Y
Sbjct: 1612 YKSKNDSESWSLHPTNNAFLQSILRLVEKVNNPNKAFLILY 1652
>UniRef50_Q0RYH4 Cluster: Putative uncharacterized protein; n=1;
Rhodococcus sp. RHA1|Rep: Putative uncharacterized
protein - Rhodococcus sp. (strain RHA1)
Length = 362
Score = 33.5 bits (73), Expect = 5.5
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = +3
Query: 573 VVTNAPFKYASSLIISETDF*APPTIATAFEASGNWVDEWFPQMITLLT 719
VV P +S+ +I + ++ AP IA + E +W+ +FPQ+I LT
Sbjct: 126 VVIKVPRNVSSNALI-DAEWAAPTEIAASAEGGNDWLRAYFPQLIDHLT 173
>UniRef50_Q0U265 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1081
Score = 33.1 bits (72), Expect = 7.3
Identities = 17/51 (33%), Positives = 26/51 (50%)
Frame = +3
Query: 339 EIVRPSTIFHFPLVTVTGNEYTTSRGVP*DPSETTPMLTHLSSVPRNQSLM 491
E RPS+ TGNE ++ + P P + TH+ S+PR++S M
Sbjct: 966 EDARPSSRRRRLANRATGNERSSEKNTPARPKRVRRLSTHIMSLPRSESSM 1016
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 683,473,044
Number of Sequences: 1657284
Number of extensions: 14161200
Number of successful extensions: 34486
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 32543
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 34349
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59677054775
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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