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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV10l18r
         (735 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U20352-1|AAC16436.1|  334|Homo sapiens malate dehydrogenase prot...   171   2e-42
D55654-1|BAA09513.1|  334|Homo sapiens cytosolic malate dehydrog...   171   2e-42
CR457405-1|CAG33686.1|  334|Homo sapiens MDH1 protein.                171   2e-42
BC001484-1|AAH01484.1|  334|Homo sapiens malate dehydrogenase 1,...   171   2e-42
AC016734-1|AAY14893.1|  334|Homo sapiens unknown protein.             171   2e-42
BC088356-1|AAH88356.1|  518|Homo sapiens malate dehydrogenase 1B...    61   5e-09
BC033509-1|AAH33509.1|  283|Homo sapiens MDH1B protein protein.        54   5e-07
AC008269-1|AAX93274.1|  283|Homo sapiens unknown protein.              54   5e-07
X63755-1|CAA45283.1|  169|Homo sapiens high-sulpher keratin prot...    33   0.80 
X55293-1|CAA39005.1|  169|Homo sapiens ultra high-sulphur kerati...    33   0.80 
BC101744-1|AAI01745.2|  169|Homo sapiens keratin associated prot...    33   0.80 
BC069531-1|AAH69531.1|  169|Homo sapiens keratin associated prot...    33   0.80 
AJ006693-1|CAA07189.1|  169|Homo sapiens ultra high sulfer kerat...    33   0.80 
AB126078-1|BAD20205.1|  169|Homo sapiens keratin associated prot...    33   0.80 
BC040341-1|AAH40341.1| 1063|Homo sapiens KIAA1618 protein.             31   5.7  
BC036891-1|AAH36891.1| 1063|Homo sapiens KIAA1618 protein.             31   5.7  
AB046838-1|BAB13444.1| 1415|Homo sapiens KIAA1618 protein protein.     31   5.7  
AY597812-1|AAT09005.1|  238|Homo sapiens UHS KerB-like protein.        30   9.9  
AJ628246-1|CAF31638.1|  167|Homo sapiens keratin associated prot...    30   9.9  
AB126080-1|BAD20207.1|  156|Homo sapiens keratin associated prot...    30   9.9  
AB126072-1|BAD20199.1|  238|Homo sapiens keratin associated prot...    30   9.9  

>U20352-1|AAC16436.1|  334|Homo sapiens malate dehydrogenase
           protein.
          Length = 334

 Score =  171 bits (416), Expect = 2e-42
 Identities = 83/157 (52%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
 Frame = -3

Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
           V   DVK VIIWGNHSSTQ+PD ++A   + G +  V E + DD++LKG FVTTVQ+RGA
Sbjct: 173 VTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGA 232

Query: 553 AVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVTV 380
           AVI                DH+RD WF   E  +VSMGV+SDG SYG P D++YSFPV +
Sbjct: 233 AVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVI 292

Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 269
            N  WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 293 KNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329


>D55654-1|BAA09513.1|  334|Homo sapiens cytosolic malate
           dehydrogenase protein.
          Length = 334

 Score =  171 bits (416), Expect = 2e-42
 Identities = 83/157 (52%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
 Frame = -3

Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
           V   DVK VIIWGNHSSTQ+PD ++A   + G +  V E + DD++LKG FVTTVQ+RGA
Sbjct: 173 VTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGA 232

Query: 553 AVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVTV 380
           AVI                DH+RD WF   E  +VSMGV+SDG SYG P D++YSFPV +
Sbjct: 233 AVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVI 292

Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 269
            N  WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 293 KNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329


>CR457405-1|CAG33686.1|  334|Homo sapiens MDH1 protein.
          Length = 334

 Score =  171 bits (416), Expect = 2e-42
 Identities = 83/157 (52%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
 Frame = -3

Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
           V   DVK VIIWGNHSSTQ+PD ++A   + G +  V E + DD++LKG FVTTVQ+RGA
Sbjct: 173 VTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGA 232

Query: 553 AVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVTV 380
           AVI                DH+RD WF   E  +VSMGV+SDG SYG P D++YSFPV +
Sbjct: 233 AVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVI 292

Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 269
            N  WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 293 KNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329


>BC001484-1|AAH01484.1|  334|Homo sapiens malate dehydrogenase 1,
           NAD (soluble) protein.
          Length = 334

 Score =  171 bits (416), Expect = 2e-42
 Identities = 83/157 (52%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
 Frame = -3

Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
           V   DVK VIIWGNHSSTQ+PD ++A   + G +  V E + DD++LKG FVTTVQ+RGA
Sbjct: 173 VTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGA 232

Query: 553 AVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVTV 380
           AVI                DH+RD WF   E  +VSMGV+SDG SYG P D++YSFPV +
Sbjct: 233 AVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVI 292

Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 269
            N  WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 293 KNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329


>AC016734-1|AAY14893.1|  334|Homo sapiens unknown protein.
          Length = 334

 Score =  171 bits (416), Expect = 2e-42
 Identities = 83/157 (52%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
 Frame = -3

Query: 733 VPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGA 554
           V   DVK VIIWGNHSSTQ+PD ++A   + G +  V E + DD++LKG FVTTVQ+RGA
Sbjct: 173 VTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGA 232

Query: 553 AVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVTV 380
           AVI                DH+RD WF   E  +VSMGV+SDG SYG P D++YSFPV +
Sbjct: 233 AVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVI 292

Query: 379 TNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 269
            N  WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 293 KNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329


>BC088356-1|AAH88356.1|  518|Homo sapiens malate dehydrogenase 1B,
           NAD (soluble) protein.
          Length = 518

 Score = 60.9 bits (141), Expect = 5e-09
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 9/158 (5%)
 Frame = -3

Query: 718 VKRVIIWGNHSSTQFPDASNA------VAIVGGAQKS--VSEIINDDAYLKGAFVTTVQK 563
           +K VIIWGN S   + D           AI G    S  V  +I D  ++K  FV  ++ 
Sbjct: 305 IKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNLIFDSEWVKREFVAILKN 364

Query: 562 RGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPV 386
               +                +  ++ W+ G+     VS+G++S+G +G P+ +V+S PV
Sbjct: 365 ----LTTTGRQFGGILAAHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPV 420

Query: 385 TVTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEAL 272
              NG W ++  L   + + Q++     +L++EK  AL
Sbjct: 421 KFENGTWVVLTDLKDVEISEQIMTRMTSDLIQEKLVAL 458


>BC033509-1|AAH33509.1|  283|Homo sapiens MDH1B protein protein.
          Length = 283

 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
 Frame = -3

Query: 490 MRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLD 314
           ++ W+ G+     VS+G++S+G +G P+ +V+S PV   NG W ++  L   + + Q++ 
Sbjct: 172 LKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFENGTWVVLTDLKDVEISEQIMT 231

Query: 313 ATGKELVEEKQEAL 272
               +L++EK  AL
Sbjct: 232 RMTSDLIQEKLVAL 245


>AC008269-1|AAX93274.1|  283|Homo sapiens unknown protein.
          Length = 283

 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
 Frame = -3

Query: 490 MRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLD 314
           ++ W+ G+     VS+G++S+G +G P+ +V+S PV   NG W ++  L   + + Q++ 
Sbjct: 172 LKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFENGTWVVLTDLKDVEISEQIMT 231

Query: 313 ATGKELVEEKQEAL 272
               +L++EK  AL
Sbjct: 232 RMTSDLIQEKLVAL 245


>X63755-1|CAA45283.1|  169|Homo sapiens high-sulpher keratin
           protein.
          Length = 169

 Score = 33.5 bits (73), Expect = 0.80
 Identities = 17/65 (26%), Positives = 27/65 (41%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSF 516
           KP+ +    C  CCS   R S  C  +    C       ++  ++ CC+ CC ++  C  
Sbjct: 103 KPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVP 162

Query: 515 CC*SC 501
            C  C
Sbjct: 163 VCYQC 167


>X55293-1|CAA39005.1|  169|Homo sapiens ultra high-sulphur keratin
           protein protein.
          Length = 169

 Score = 33.5 bits (73), Expect = 0.80
 Identities = 17/65 (26%), Positives = 27/65 (41%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSF 516
           KP+ +    C  CCS   R S  C  +    C       ++  ++ CC+ CC ++  C  
Sbjct: 103 KPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVP 162

Query: 515 CC*SC 501
            C  C
Sbjct: 163 VCYQC 167


>BC101744-1|AAI01745.2|  169|Homo sapiens keratin associated protein
           5-9 protein.
          Length = 169

 Score = 33.5 bits (73), Expect = 0.80
 Identities = 17/65 (26%), Positives = 27/65 (41%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSF 516
           KP+ +    C  CCS   R S  C  +    C       ++  ++ CC+ CC ++  C  
Sbjct: 103 KPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVP 162

Query: 515 CC*SC 501
            C  C
Sbjct: 163 VCYQC 167


>BC069531-1|AAH69531.1|  169|Homo sapiens keratin associated protein
           5-9 protein.
          Length = 169

 Score = 33.5 bits (73), Expect = 0.80
 Identities = 17/65 (26%), Positives = 27/65 (41%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSF 516
           KP+ +    C  CCS   R S  C  +    C       ++  ++ CC+ CC ++  C  
Sbjct: 103 KPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVP 162

Query: 515 CC*SC 501
            C  C
Sbjct: 163 VCYQC 167


>AJ006693-1|CAA07189.1|  169|Homo sapiens ultra high sulfer keratin
           protein.
          Length = 169

 Score = 33.5 bits (73), Expect = 0.80
 Identities = 17/65 (26%), Positives = 27/65 (41%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSF 516
           KP+ +    C  CCS   R S  C  +    C       ++  ++ CC+ CC ++  C  
Sbjct: 103 KPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVP 162

Query: 515 CC*SC 501
            C  C
Sbjct: 163 VCYQC 167


>AB126078-1|BAD20205.1|  169|Homo sapiens keratin associated protein
           protein.
          Length = 169

 Score = 33.5 bits (73), Expect = 0.80
 Identities = 17/65 (26%), Positives = 27/65 (41%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNGSKTWCCRYCCQENVICSF 516
           KP+ +    C  CCS   R S  C  +    C       ++  ++ CC+ CC ++  C  
Sbjct: 103 KPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVP 162

Query: 515 CC*SC 501
            C  C
Sbjct: 163 VCYQC 167


>BC040341-1|AAH40341.1| 1063|Homo sapiens KIAA1618 protein.
          Length = 1063

 Score = 30.7 bits (66), Expect = 5.7
 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
 Frame = -3

Query: 367 WKIVEGLTISDFARQMLDATG-KELVEEKQEALDV 266
           W  +EGL+ S F  QMLD +   + + EKQ  L +
Sbjct: 719 WAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSI 753


>BC036891-1|AAH36891.1| 1063|Homo sapiens KIAA1618 protein.
          Length = 1063

 Score = 30.7 bits (66), Expect = 5.7
 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
 Frame = -3

Query: 367 WKIVEGLTISDFARQMLDATG-KELVEEKQEALDV 266
           W  +EGL+ S F  QMLD +   + + EKQ  L +
Sbjct: 719 WAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSI 753


>AB046838-1|BAB13444.1| 1415|Homo sapiens KIAA1618 protein protein.
          Length = 1415

 Score = 30.7 bits (66), Expect = 5.7
 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
 Frame = -3

Query: 367 WKIVEGLTISDFARQMLDATG-KELVEEKQEALDV 266
           W  +EGL+ S F  QMLD +   + + EKQ  L +
Sbjct: 584 WAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSI 618


>AY597812-1|AAT09005.1|  238|Homo sapiens UHS KerB-like protein.
          Length = 238

 Score = 29.9 bits (64), Expect = 9.9
 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 2/70 (2%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNG-SKTWCCRYCCQENVICS 519
           KP  +    C  CCS    C   C  +       +   C    S++ CC+ CC  +   S
Sbjct: 152 KPSCSQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKPCCCSSGCGS 211

Query: 518 FCC-*SCIRP 492
            CC  SC +P
Sbjct: 212 SCCQSSCCKP 221


>AJ628246-1|CAF31638.1|  167|Homo sapiens keratin associated protein
           5-9 protein.
          Length = 167

 Score = 29.9 bits (64), Expect = 9.9
 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 2/70 (2%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNG-SKTWCCRYCCQENVICS 519
           KP  +    C  CCS    C   C  +       +   C    S++ CC+ CC  +   S
Sbjct: 81  KPSCSQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKPCCCSSGCGS 140

Query: 518 FCC-*SCIRP 492
            CC  SC +P
Sbjct: 141 SCCQSSCCKP 150


>AB126080-1|BAD20207.1|  156|Homo sapiens keratin associated protein
           protein.
          Length = 156

 Score = 29.9 bits (64), Expect = 9.9
 Identities = 12/27 (44%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
 Frame = -2

Query: 569 SKTWCCRYCCQENVICSFCC-*SCIRP 492
           S++ CC+ CC  +   SFCC  SC +P
Sbjct: 83  SQSNCCKPCCSSSGCGSFCCQSSCSKP 109


>AB126072-1|BAD20199.1|  238|Homo sapiens keratin associated protein
           protein.
          Length = 238

 Score = 29.9 bits (64), Expect = 9.9
 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 2/70 (2%)
 Frame = -2

Query: 695 KPFINPVP*CFECCSYCWRCSKICF*NYQ*RCIFERRICNNG-SKTWCCRYCCQENVICS 519
           KP  +    C  CCS    C   C  +       +   C    S++ CC+ CC  +   S
Sbjct: 152 KPSCSQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKPCCCSSGCGS 211

Query: 518 FCC-*SCIRP 492
            CC  SC +P
Sbjct: 212 SCCQSSCCKP 221


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,211,581
Number of Sequences: 237096
Number of extensions: 2152154
Number of successful extensions: 4133
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3539
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4032
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8735159784
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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