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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV10l18f
         (646 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=12...   236   4e-61
UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|R...   199   5e-50
UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium t...   194   2e-48
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or...   191   1e-47
UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular org...   180   2e-44
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re...   177   2e-43
UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmi...   176   4e-43
UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Re...   175   1e-42
UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putativ...   173   4e-42
UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=...   171   9e-42
UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium t...   167   2e-40
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte...   165   6e-40
UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18; Trichomonad...   162   8e-39
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta...   160   3e-38
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi...   160   3e-38
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr...   158   1e-37
UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Re...   158   1e-37
UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplas...   157   3e-37
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea...   152   8e-36
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t...   146   5e-34
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=...   142   7e-33
UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Re...   140   3e-32
UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella ve...   138   1e-31
UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomo...   112   8e-24
UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;...    86   8e-16
UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate deh...    76   8e-13
UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1; ...    74   3e-12
UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella chej...    69   1e-10
UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;...    69   1e-10
UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21; Amniota|...    68   2e-10
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale...    57   4e-07
UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep: Zgc:1...    53   7e-06
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale...    51   3e-05
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere...    49   1e-04
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu...    48   1e-04
UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to tetratrico...    47   3e-04
UniRef50_A2Q2G7 Cluster: Putative uncharacterized protein; n=1; ...    47   3e-04
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A...    47   3e-04
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae...    45   0.001
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;...    45   0.002
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R...    44   0.003
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi...    44   0.004
UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein NCU048...    43   0.007
UniRef50_A0T7L1 Cluster: Putative uncharacterized protein; n=1; ...    42   0.010
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti...    42   0.017
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R...    42   0.017
UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD (so...    41   0.029
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2...    41   0.029
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o...    41   0.029
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter...    41   0.029
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re...    41   0.029
UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1; ...    40   0.039
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi...    40   0.039
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ...    39   0.090
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;...    38   0.21 
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea...    38   0.21 
UniRef50_Q9HHJ2 Cluster: Vng6368h; n=1; Halobacterium salinarum|...    38   0.27 
UniRef50_O97299 Cluster: Putative uncharacterized protein MAL3P7...    37   0.36 
UniRef50_A3KPA8 Cluster: LOC568298 protein; n=2; Danio rerio|Rep...    36   0.84 
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ...    36   0.84 
UniRef50_Q6DXR3 Cluster: Predicted protein; n=3; eurosids II|Rep...    36   0.84 
UniRef50_Q54HN9 Cluster: Putative uncharacterized protein; n=1; ...    36   0.84 
UniRef50_P19980 Cluster: Malate dehydrogenase; n=5; Bacteria|Rep...    36   0.84 
UniRef50_A7P2B9 Cluster: Chromosome chr1 scaffold_5, whole genom...    36   1.1  
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte...    36   1.1  
UniRef50_Q88SJ4 Cluster: Extracellular protein, gamma-D-glutamat...    35   1.5  
UniRef50_A6W575 Cluster: Putative uncharacterized protein; n=1; ...    35   1.5  
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm...    35   1.5  
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|...    35   1.5  
UniRef50_A3BI71 Cluster: Putative uncharacterized protein; n=7; ...    35   1.9  
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop...    35   1.9  
UniRef50_Q1J2E3 Cluster: Peptidase M23B precursor; n=1; Deinococ...    34   2.6  
UniRef50_Q869R4 Cluster: Similar to Streptococcus pneumoniae. Ce...    34   2.6  
UniRef50_Q8IEN1 Cluster: Putative uncharacterized protein MAL13P...    34   3.4  
UniRef50_Q9P5T7 Cluster: Related to glucan 1, 4-alpha-glucosidas...    34   3.4  
UniRef50_P58338 Cluster: Ornithine cyclodeaminase 1; n=34; Prote...    34   3.4  
UniRef50_Q9P5L4 Cluster: Related to DOS1 protein; n=3; Sordariom...    33   4.5  
UniRef50_Q8PTW7 Cluster: Putative uncharacterized protein; n=1; ...    33   4.5  
UniRef50_P35453 Cluster: Homeobox protein Hox-D13; n=47; Craniat...    33   4.5  
UniRef50_A7NQN6 Cluster: Extracellular solute-binding protein fa...    33   5.9  
UniRef50_Q7PWG9 Cluster: ENSANGP00000006494; n=2; cellular organ...    33   5.9  
UniRef50_P20659 Cluster: Protein trithorax; n=4; Drosophila mela...    33   5.9  
UniRef50_UPI0000DD83F5 Cluster: PREDICTED: similar to keratin as...    33   7.8  
UniRef50_Q4RJK7 Cluster: Chromosome 3 SCAF15037, whole genome sh...    33   7.8  
UniRef50_Q2NDZ8 Cluster: Putative uncharacterized protein; n=1; ...    33   7.8  
UniRef50_A7HYU6 Cluster: UspA domain protein; n=1; Parvibaculum ...    33   7.8  
UniRef50_A6FWZ9 Cluster: L-lysine aminotransferase; n=1; Plesioc...    33   7.8  
UniRef50_Q6BCL3 Cluster: Beta-1,4-endoglucanase precursor; n=5; ...    33   7.8  
UniRef50_Q22MV0 Cluster: PWI domain containing protein; n=1; Tet...    33   7.8  

>UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=124;
           cellular organisms|Rep: Malate dehydrogenase,
           cytoplasmic - Homo sapiens (Human)
          Length = 334

 Score =  236 bits (577), Expect = 4e-61
 Identities = 114/159 (71%), Positives = 131/159 (82%)
 Frame = +1

Query: 166 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 345
           M+EPIRV+VTGAAGQIAYSLLY I +G+VFG  QP+ L LLDI PMMGVL+GV+MEL DC
Sbjct: 1   MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC 60

Query: 346 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVA 525
           ALPLL  V+ T   + AFKD+  A LVG+MPR+EGMERKDLL ANV+IFK QG ALDK A
Sbjct: 61  ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA 120

Query: 526 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           +K VKV+VVGNPANTN L  SK APSIPKENF+ +TRLD
Sbjct: 121 KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLD 159


>UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|Rep:
           Malate dehydrogenase - Caenorhabditis elegans
          Length = 336

 Score =  199 bits (485), Expect = 5e-50
 Identities = 99/160 (61%), Positives = 121/160 (75%), Gaps = 1/160 (0%)
 Frame = +1

Query: 166 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 345
           M+ P+RV+VTGAAGQI YS++ +IA G VFG +QPV L LLD+     +LEGVV EL DC
Sbjct: 1   MSAPLRVLVTGAAGQIGYSIVIRIADGTVFGKEQPVELVLLDVPQCSNILEGVVFELQDC 60

Query: 346 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVA 525
           ALP L  V+   + + AF  +  AFLVGAMPR+EGMERKDLLAANV+IFK QG+AL + A
Sbjct: 61  ALPTLFSVVAVTDEKSAFTGIDYAFLVGAMPRREGMERKDLLAANVKIFKSQGKALAEYA 120

Query: 526 RKDVKVLVVGNPANTNALICSKYAP-SIPKENFTAMTRLD 642
           +   KV+VVGNPANTNA I +KYA   IP +NF+AMTRLD
Sbjct: 121 KPTTKVIVVGNPANTNAFIAAKYAAGKIPAKNFSAMTRLD 160


>UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium
           tetraurelia|Rep: Malate dehydrogenase - Paramecium
           tetraurelia
          Length = 356

 Score =  194 bits (472), Expect = 2e-48
 Identities = 94/157 (59%), Positives = 114/157 (72%)
 Frame = +1

Query: 175 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 354
           P+RV VTGAAG I Y+L++ I  G + GP Q + L LL++      LEG +MEL DCA P
Sbjct: 26  PVRVTVTGAAGNIGYALVHMIGQGRLLGPNQQIILTLLELPMAKDQLEGTMMELRDCAFP 85

Query: 355 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKD 534
           +L  +  T   ++ F     A LVGA PR  GMERKDLLAAN RIFKEQG+AL+K A K+
Sbjct: 86  ILKEIRGTTQYDQGFMGCEIAILVGAKPRGPGMERKDLLAANARIFKEQGEALEKYASKN 145

Query: 535 VKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 645
           VKVLVVGNPANTNALI +++APSIPK NFTA+TRLDQ
Sbjct: 146 VKVLVVGNPANTNALITAQFAPSIPKSNFTALTRLDQ 182


>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
           organisms|Rep: Malate dehydrogenase - Acidovorax sp.
           (strain JS42)
          Length = 328

 Score =  191 bits (465), Expect = 1e-47
 Identities = 97/159 (61%), Positives = 116/159 (72%), Gaps = 2/159 (1%)
 Frame = +1

Query: 172 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAP--MMGVLEGVVMELADC 345
           +P+RV VTGAAGQI Y+LL++IASG + G  QPV L LL+I        L+GV+MEL DC
Sbjct: 4   KPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQNALKGVIMELEDC 63

Query: 346 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVA 525
           A PLLAG+   ++P  AFKD   A LVGA PR  GMER DLLAAN +IF  QG+AL+ VA
Sbjct: 64  AFPLLAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVA 123

Query: 526 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
            ++VKVLVVGNPANTNA I  K AP +P +NFTAM RLD
Sbjct: 124 SRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLD 162


>UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular
           organisms|Rep: Malate dehydrogenase - Oryza sativa
           (Rice)
          Length = 352

 Score =  180 bits (439), Expect = 2e-44
 Identities = 86/157 (54%), Positives = 112/157 (71%)
 Frame = +1

Query: 172 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 351
           +P++V+VTGAAGQI Y+++  IA G + G  QPV LHLLD+      L GV MEL D AL
Sbjct: 25  KPVKVLVTGAAGQIGYAIVAMIAKGLMLGADQPVVLHLLDLPVAANALNGVRMELIDAAL 84

Query: 352 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARK 531
           PLL GV+ T++  EAFK V  A L+G  PR++GMERKDL++ NV I+K Q  AL + A  
Sbjct: 85  PLLRGVVATSDEAEAFKGVNVAILIGGWPRRDGMERKDLISKNVTIYKSQASALQQHAAP 144

Query: 532 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           + KVLVV NPANTNAL+  ++AP+IP +N T +TRLD
Sbjct: 145 NCKVLVVANPANTNALVLKEFAPAIPAKNITCLTRLD 181


>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
           Malate dehydrogenase - Bdellovibrio bacteriovorus
          Length = 335

 Score =  177 bits (430), Expect = 2e-43
 Identities = 95/164 (57%), Positives = 112/164 (68%), Gaps = 5/164 (3%)
 Frame = +1

Query: 166 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMG--VLEGVVMELA 339
           M  P+RV VTGAAGQI Y+LL++IASGA+ G  QPV L LL+I        L+GV+MEL 
Sbjct: 1   MKAPVRVAVTGAAGQIGYALLFRIASGAMLGADQPVILQLLEIPDEKAQKALKGVMMELE 60

Query: 340 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 519
           DCA PLL  ++ T +P  AFKD   A LVGA PR  GMERKDLL AN +IF  QG+A+ K
Sbjct: 61  DCAFPLLHSMIATGDPAVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGK 120

Query: 520 VARKDVKVLVVGNPANTNALICSKYAPS---IPKENFTAMTRLD 642
            A  +VKVLVVGNPANTNA I  K A     +  +NFTAM RLD
Sbjct: 121 YANPNVKVLVVGNPANTNAYIAMKSAMKHGRVKAKNFTAMLRLD 164


>UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmic
           (EC 1.1.1.37) (Cytosolic malate dehydrogenase).; n=1;
           Takifugu rubripes|Rep: Malate dehydrogenase, cytoplasmic
           (EC 1.1.1.37) (Cytosolic malate dehydrogenase). -
           Takifugu rubripes
          Length = 382

 Score =  176 bits (428), Expect = 4e-43
 Identities = 91/135 (67%), Positives = 104/135 (77%), Gaps = 1/135 (0%)
 Frame = +1

Query: 163 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           + AEPIRV+VTGAAGQIAYSLL+ IA G VFG  QP+ L LLDI  M+ VLEGVVMEL D
Sbjct: 90  RQAEPIRVLVTGAAGQIAYSLLFSIAKGDVFGKDQPIILLLLDITAMLPVLEGVVMELQD 149

Query: 343 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKV 522
           CALPLL  ++ T   E AFKD+ AA LVG+MPRKEGMERKDLL ANV IFK QG AL+K 
Sbjct: 150 CALPLLRDIIATDMEEVAFKDLDAAILVGSMPRKEGMERKDLLKANVAIFKSQGSALEKF 209

Query: 523 ARKDVKVLV-VGNPA 564
           ++K VKV +  G PA
Sbjct: 210 SKKTVKVAMRCGVPA 224


>UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Rep:
           Malate dehydrogenase - Frankia sp. (strain CcI3)
          Length = 329

 Score =  175 bits (425), Expect = 1e-42
 Identities = 88/156 (56%), Positives = 109/156 (69%)
 Frame = +1

Query: 175 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 354
           P+ V VTGAAGQI Y+LL++IASG + G   PV L LL+I   +   EG  +EL D A P
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGADTPVKLRLLEIPQAVRAAEGTALELEDSAFP 64

Query: 355 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKD 534
           LLAGV    + + AF+    A LVGA PR +GMER DLL+AN  IFK QG+A++  A +D
Sbjct: 65  LLAGVDVFDDAKRAFEGTNVALLVGARPRTKGMERGDLLSANGGIFKPQGEAINSGAAED 124

Query: 535 VKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           ++VLVVGNPANTNALI   +AP +P E FTAMTRLD
Sbjct: 125 IRVLVVGNPANTNALIAQTHAPDVPAERFTAMTRLD 160


>UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putative;
           n=7; Eukaryota|Rep: Cytosolic malate dehydrogenase,
           putative - Leishmania major
          Length = 324

 Score =  173 bits (420), Expect = 4e-42
 Identities = 92/156 (58%), Positives = 107/156 (68%), Gaps = 1/156 (0%)
 Frame = +1

Query: 178 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 357
           ++V VTGAAGQI Y+L+  IA GA+ GP  PV L LLDI P +  L GV  EL DCA PL
Sbjct: 4   VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDCAFPL 63

Query: 358 LAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDV 537
           L  V+ TA+P  AF  VA A + GA PRK GMERKDLL  N RIFKEQG+A+  VA  D 
Sbjct: 64  LDKVVVTADPRVAFDGVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEAIAAVAASDC 123

Query: 538 KVLVVGNPANTNALICSKYAP-SIPKENFTAMTRLD 642
           +V+VVGNPANTNALI  K A   +   + TAMTRLD
Sbjct: 124 RVVVVGNPANTNALILLKSAQGKLNPRHVTAMTRLD 159


>UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=2;
           Entamoeba histolytica|Rep: NAD-specific malate
           dehydrogenase 1 - Entamoeba histolytica
          Length = 355

 Score =  171 bits (417), Expect = 9e-42
 Identities = 89/159 (55%), Positives = 109/159 (68%)
 Frame = +1

Query: 169 AEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCA 348
           ++P+ V+VTGAAGQI Y+LL+ IA G +FGP Q V+LHL DI  M+  +EGV MELADC 
Sbjct: 22  SKPLHVLVTGAAGQIGYNLLFLIAHGLMFGPNQTVYLHLYDI--MVEAMEGVKMELADCC 79

Query: 349 LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVAR 528
            PL+ GV+ +   E AFKDV  A LV  MPRK GMERK+L+  N RI KEQ  AL   A 
Sbjct: 80  FPLVKGVVASNKTEVAFKDVECAILVAGMPRKVGMERKELIGINTRIMKEQALALKNFAN 139

Query: 529 KDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 645
             V+VLVV NPANTNAL+ +  A  I  +  T +TRLDQ
Sbjct: 140 PHVRVLVVANPANTNALVVANNA-GIDVKQITCLTRLDQ 177


>UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium
           tetraurelia|Rep: Malate dehydrogenase - Paramecium
           tetraurelia
          Length = 360

 Score =  167 bits (406), Expect = 2e-40
 Identities = 79/145 (54%), Positives = 101/145 (69%)
 Frame = +1

Query: 208 QIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANP 387
           ++ YSL++++ASG + GP QPV LHL+D+   M  L GVVME+ DCA PL+ G++ T N 
Sbjct: 51  KLGYSLIFRVASGEMLGPNQPVILHLIDLPFAMAALNGVVMEIQDCAFPLVQGIVATDNQ 110

Query: 388 EEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPAN 567
              FKDV  A +VGA PR  GMER DLL  N +IF E G+ ++  A +D+KV+VVGNP N
Sbjct: 111 SVGFKDVNYALMVGAKPRGPGMERGDLLKDNGKIFTETGKYINDHASRDIKVVVVGNPCN 170

Query: 568 TNALICSKYAPSIPKENFTAMTRLD 642
           TN LI +     IPKENFTAMTRLD
Sbjct: 171 TNCLILANQIKDIPKENFTAMTRLD 195


>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
           intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
           ATCC 50803
          Length = 331

 Score =  165 bits (402), Expect = 6e-40
 Identities = 82/160 (51%), Positives = 111/160 (69%), Gaps = 1/160 (0%)
 Frame = +1

Query: 166 MAEPI-RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           M +P+ RV ++GAAGQI YS+L++IA+G + G  QPV + +L++   +   EGV MEL D
Sbjct: 1   MTKPVLRVCISGAAGQICYSVLFRIAAGDMLGYDQPVHIVMLEVPAALKAAEGVAMELVD 60

Query: 343 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKV 522
           CA PLL+G   T++  EAFKDV    L GA PRK GMER +LL+ N  IF+ QG A+++ 
Sbjct: 61  CAFPLLSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQIQGAAINEH 120

Query: 523 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           A+   ++LV+GNPANTNAL+ S     IPK N TAM+RLD
Sbjct: 121 AKPTCRILVIGNPANTNALVLSTQLTKIPKTNVTAMSRLD 160


>UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18;
           Trichomonadinae|Rep: Malate dehydrogenase - Trichomonas
           vaginalis G3
          Length = 339

 Score =  162 bits (393), Expect = 8e-39
 Identities = 81/160 (50%), Positives = 107/160 (66%)
 Frame = +1

Query: 166 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 345
           M EP RV++TGAAGQI Y L + IASG ++G ++PV LHL DI      L  + MEL DC
Sbjct: 1   MVEPARVLITGAAGQIGYVLSHWIASGELYG-ERPVILHLFDIPVAQNRLTALTMELQDC 59

Query: 346 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVA 525
           A P LAG + T  PE+AFKD+  AFLV ++P K G  R DL+ +N  IFK  G+ L + A
Sbjct: 60  AFPHLAGYVATTEPEQAFKDIDCAFLVASVPMKSGQIRSDLIGSNSIIFKNTGEWLSQYA 119

Query: 526 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 645
           +  VKVLV+GNP NTNA I   +A ++  ENF++++ LDQ
Sbjct: 120 KPTVKVLVIGNPDNTNAEIALLHAKNLKPENFSSLSLLDQ 159


>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
           putative; n=3; Oligohymenophorea|Rep: Malate
           dehydrogenase, cytoplasmic, putative - Tetrahymena
           thermophila SB210
          Length = 365

 Score =  160 bits (388), Expect = 3e-38
 Identities = 84/160 (52%), Positives = 106/160 (66%)
 Frame = +1

Query: 163 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           K  + I V VTGAAGQI Y+ L  + +G  FG ++ + L LLD+     +L+GV +EL D
Sbjct: 41  KENDEINVCVTGAAGQIGYAFLPLLLTGQCFGDKK-INLRLLDVPQAESILQGVELELQD 99

Query: 343 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKV 522
            A PLL  +   +N    F+DV  A  +G  PRK GMERKDLL  N  IFK+QGQALD V
Sbjct: 100 GAYPLLKSIKTGSNESILFQDVDVAVFIGGFPRKPGMERKDLLTINGNIFKKQGQALDTV 159

Query: 523 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           A+K  K LVV NPANTN LI ++ A SIPK+NF+A+TRLD
Sbjct: 160 AKKTCKSLVVANPANTNCLILAETAKSIPKQNFSALTRLD 199


>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
           Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
           vaginalis G3
          Length = 332

 Score =  160 bits (388), Expect = 3e-38
 Identities = 81/159 (50%), Positives = 107/159 (67%)
 Frame = +1

Query: 166 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 345
           M +P+ V+VTGAAGQI Y L ++IA+G +FG ++ V LHLL+I+P M  LE VVMEL DC
Sbjct: 1   MTQPLHVLVTGAAGQIGYVLAFRIANGDLFG-ERDVVLHLLEISPAMKALEAVVMELHDC 59

Query: 346 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVA 525
             P L  V+ T++ EEAF+DV  AFLVG+ P+K   +  D    N  I+ E G+AL   A
Sbjct: 60  TFPHLLHVIGTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFA 119

Query: 526 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           +  VKVLV+G P NTNAL+    A ++  +NF AMTRLD
Sbjct: 120 KPTVKVLVIGMPTNTNALVAMTAAVNLSPKNFCAMTRLD 158


>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
           Trichomonadida|Rep: Cytosolic malate dehydrogenase -
           Tetratrichomonas gallinarum
          Length = 314

 Score =  158 bits (383), Expect = 1e-37
 Identities = 83/141 (58%), Positives = 102/141 (72%)
 Frame = +1

Query: 220 SLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAF 399
           +L ++IA G + G ++ VFLH L+I   M  LEG VMEL DCA P +AG++ T   EEAF
Sbjct: 1   ALTFRIAKGDLCGDRK-VFLHHLEIPFGMKALEGCVMELQDCAFPNVAGIVWTDKIEEAF 59

Query: 400 KDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNAL 579
           KDV  AFLVG+ PRK+GM+R DLLA N  IF  QG+AL   A+KDVKVLVVGNPANTN L
Sbjct: 60  KDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDVKVLVVGNPANTNCL 119

Query: 580 ICSKYAPSIPKENFTAMTRLD 642
           I    AP++ K+N+ AMTRLD
Sbjct: 120 IAQASAPNLSKKNWCAMTRLD 140


>UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Rep:
           Malate dehydrogenase - Mastigamoeba balamuthi
           (Phreatamoeba balamuthi)
          Length = 382

 Score =  158 bits (383), Expect = 1e-37
 Identities = 84/160 (52%), Positives = 102/160 (63%), Gaps = 2/160 (1%)
 Frame = +1

Query: 169 AEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIA--PMMGVLEGVVMELAD 342
           A P+ V +TG AGQIAYSL + IA G + G  QPV L LLD+         E VVMEL D
Sbjct: 44  AAPLHVTLTGGAGQIAYSLAFLIARGQMLGLYQPVVLRLLDLPRPEKQRAQEAVVMELKD 103

Query: 343 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKV 522
           CA  LL  V+ TA+P EAF       LVG+ PR  G  R+DLLA N  IFK QG+A+   
Sbjct: 104 CAFGLLRDVVATADPREAFAGAHVVVLVGSSPRAAGQLRRDLLAQNAAIFKAQGKAVSDY 163

Query: 523 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           A  DV+VLVV NPANTN L+ S+ AP+IP+ + + MTRLD
Sbjct: 164 ADPDVRVLVVANPANTNCLVFSRCAPNIPRTHVSCMTRLD 203


>UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplast
           precursor; n=62; cellular organisms|Rep: Malate
           dehydrogenase [NADP], chloroplast precursor - Zea mays
           (Maize)
          Length = 432

 Score =  157 bits (380), Expect = 3e-37
 Identities = 83/156 (53%), Positives = 104/156 (66%)
 Frame = +1

Query: 178 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 357
           + V V+GAAG I+  LL+++ASG VFG  QP+ L LL        LEGV MEL D   PL
Sbjct: 90  VNVAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYPL 149

Query: 358 LAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDV 537
           L  V    +P   F+DV  A L+GA PR  GMER  LL  N +IF +QG+AL+ VA ++ 
Sbjct: 150 LREVSIGIDPYVVFQDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASRND 209

Query: 538 KVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 645
           +VLVVGNP NTNALIC K AP+IP +NF A+TRLD+
Sbjct: 210 EVLVVGNPCNTNALICLKNAPNIPAKNFHALTRLDE 245


>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
           Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 328

 Score =  152 bits (368), Expect = 8e-36
 Identities = 79/158 (50%), Positives = 101/158 (63%)
 Frame = +1

Query: 172 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 351
           E +RV VTG  GQIAY+ L+ +A G VFG  + V L + D+      L GV MEL D A 
Sbjct: 5   EVVRVAVTGGKGQIAYNFLFALAHGDVFGVDRGVDLRIYDVPGTERALSGVRMELDDGAY 64

Query: 352 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARK 531
           PLL  +  T +  +AF  + AAFL+GA+PR  GMER DLL  N +IF  QG AL+  A++
Sbjct: 65  PLLHRLRVTTSLNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR 124

Query: 532 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 645
           D K+ VVGNP NTN  I  K+AP + ++NF AM RLDQ
Sbjct: 125 DAKIFVVGNPVNTNCWIAMKHAPRLHRKNFHAMLRLDQ 162


>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
           tetraurelia|Rep: Malate dehydrogenase - Paramecium
           tetraurelia
          Length = 322

 Score =  146 bits (353), Expect = 5e-34
 Identities = 71/157 (45%), Positives = 99/157 (63%)
 Frame = +1

Query: 172 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 351
           E +++ +TG AG +A +    + SG VFG  Q   L LL++   +  LEG+ M++ DCA 
Sbjct: 5   EELKIAITGGAGNLASAFYPLLGSGQVFGSTQKFSLQLLELPEKLQELEGIKMQIQDCAF 64

Query: 352 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARK 531
           PLL  V  +++P  AFKD   A  +GAMPRK GMER DLL  N  IF +QGQ L++ A+ 
Sbjct: 65  PLLNNVTVSSDPAIAFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKS 124

Query: 532 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
            VKVLVV NP+NTN    +     IP++NFT++ +LD
Sbjct: 125 TVKVLVVANPSNTNCATLAHQCTKIPQQNFTSLMQLD 161


>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
           Entamoeba histolytica|Rep: NAD-specific malate
           dehydrogenase 2 - Entamoeba histolytica
          Length = 329

 Score =  142 bits (344), Expect = 7e-33
 Identities = 74/162 (45%), Positives = 101/162 (62%)
 Frame = +1

Query: 160 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 339
           +   EP+ V++TGAAGQI Y+L + I  G +F     V LHL D+  M   L+G+ MEL 
Sbjct: 10  VNRTEPLHVLITGAAGQIGYNLCFLIGRGFLFDCD--VILHLYDLNDM--ALKGLSMELT 65

Query: 340 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 519
           DC LP L G++ T     AF +V  A +V  +PRK GM+R DL+  N ++ +  G+AL  
Sbjct: 66  DCCLPKLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGT 125

Query: 520 VARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 645
            + KDV+V+VV NPANTNA +  K    IP E+ TA+TRLDQ
Sbjct: 126 YSNKDVRVVVVANPANTNAYVICK-TSGIPPEHITALTRLDQ 166


>UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Rep:
           Malate dehydrogenase - Trypanosoma cruzi
          Length = 332

 Score =  140 bits (338), Expect = 3e-32
 Identities = 76/155 (49%), Positives = 98/155 (63%), Gaps = 1/155 (0%)
 Frame = +1

Query: 181 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 360
           +VVV+GAAG++ Y+LL  IA G + GP Q + L+LLDI   M  LEG+  EL DCA PLL
Sbjct: 9   KVVVSGAAGKVGYALLPLIAGGRMLGPNQHLQLNLLDIEAAMKCLEGIRAELMDCAFPLL 68

Query: 361 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVK 540
             V+ T  P  AF++V  A L G+ P K G  R+DLL  N  IF E G+ L ++A KD  
Sbjct: 69  DRVVITHQPAVAFENVDIAILCGSFPAKPGTLRRDLLQKNAAIFSEHGRLLGELASKDCH 128

Query: 541 VLVVGNPANTNALICSKYA-PSIPKENFTAMTRLD 642
           V VVGNP NTNAL+    +   I  +N +A+TRLD
Sbjct: 129 VCVVGNPVNTNALVLLNASNGKIKPKNVSALTRLD 163


>UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 462

 Score =  138 bits (334), Expect = 1e-31
 Identities = 65/161 (40%), Positives = 101/161 (62%)
 Frame = +1

Query: 163 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           K   P+RV V+ A+G +AY +L  +  G VFG Q+ V ++LLD       L+GV  E+ D
Sbjct: 127 KKINPLRVCVSKASGPLAYGMLASLVQGEVFGFQEEVSIYLLDTPENQEALQGVAYEIED 186

Query: 343 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKV 522
           CA PL  GV  T++P  AFKD +   L+      EG ++K+ L ++ ++F++ G+AL+  
Sbjct: 187 CAWPLFRGVHITSDPAVAFKDASVVVLLDGKAINEGTDKKEYLLSHAKLFRDYGKALEAH 246

Query: 523 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 645
           A+ D KVL  G PAN +  I SK+APSI K+NF +++R+++
Sbjct: 247 AKPDCKVLTAGGPANFSTFIASKFAPSIQKKNFVSLSRIEE 287


>UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomonas
           acosta|Rep: Malate dehydrogenase - Hypotrichomonas
           acosta
          Length = 318

 Score =  112 bits (269), Expect = 8e-24
 Identities = 59/140 (42%), Positives = 84/140 (60%)
 Frame = +1

Query: 223 LLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFK 402
           + ++IA+G + G ++ V LHLL++   +   EG+ +EL DCA   L   + T   EEA K
Sbjct: 1   MAFRIANGDLLGNRR-VCLHLLELPVALKACEGLALELEDCAFQNLEKTIVTDKLEEACK 59

Query: 403 DVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNALI 582
           D+  AFLV ++P K G  R +LL  N  IFK  G+AL + A+  V+ LVVGNP N+N L+
Sbjct: 60  DIDIAFLVASVPLKPGEHRVNLLTKNTPIFKAIGEALSEYAKPTVRALVVGNPVNSNCLV 119

Query: 583 CSKYAPSIPKENFTAMTRLD 642
               AP +  ENF+ M  LD
Sbjct: 120 AMLNAPKLSAENFSCMCTLD 139


>UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG5362-PA - Nasonia vitripennis
          Length = 358

 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 54/156 (34%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
 Frame = +1

Query: 181 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 360
           RVV+T A   IA SL Y+I S  +FG  Q + L L D      +L+ V +E+  CA  LL
Sbjct: 19  RVVITEATSFIARSLAYRILSDEIFGADQEIVLSLYDSGEQAMLLQTVAIEITACAPNLL 78

Query: 361 AGVLPTANPEEAFKDVAAAFLVGA-----MPRKEGMERKDLLAANVRIFKEQGQALDKVA 525
             V+ +++   AF      F +G        + + ++       +V   K+   AL+K A
Sbjct: 79  KDVVYSSDTSLAFAGADWVFFIGKSRDYNFSKSQELQDDPFFIESVLETKKMAIALEKFA 138

Query: 526 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMT 633
           + DVK++ +G   NT+A + S+YAPSIPK N T +T
Sbjct: 139 KIDVKIITLG---NTSARLISEYAPSIPKNNITGVT 171


>UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate
           dehydrogenase 1B, NAD (soluble); n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to Malate
           dehydrogenase 1B, NAD (soluble) - Monodelphis domestica
          Length = 655

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 47/160 (29%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
 Frame = +1

Query: 163 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           +M  P++V +TGA+    Y L+  +ASG VFG ++ + ++LL        L G+VME  D
Sbjct: 261 EMINPLQVWITGASCPTCYHLIPILASGEVFGLEEEISINLLSSTYNEDNLRGLVMESED 320

Query: 343 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKV 522
            ALPLL  +       EAF +     ++  +   E    +D +     I +  G  +DK 
Sbjct: 321 LALPLLRNISLCTEINEAFLEAHVIVILNDIIEDESEPLEDRIRDRFPICQLYGSLIDKN 380

Query: 523 ARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRL 639
           A ++VKV+V G    N    +  ++ PS+   N  A+  +
Sbjct: 381 ANENVKVIVAGKTFLNLTTSLIIQHTPSVNPRNIIAVAMI 420


>UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1;
           Branchiostoma floridae|Rep: Putative uncharacterized
           protein - Branchiostoma floridae (Florida lancelet)
           (Amphioxus)
          Length = 522

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 43/162 (26%), Positives = 83/162 (51%), Gaps = 1/162 (0%)
 Frame = +1

Query: 163 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           + ++P+ V V  AA   AY +L  + +G +   ++ + LHL D    +  L+G+ ME+ D
Sbjct: 127 RQSKPLHVCVINAARSPAYHVLPSLVNGKILREEE-IALHLHDSEENLEKLKGLEMEVFD 185

Query: 343 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKV 522
            + P L  +  T +   AF++   A ++    +    +    +   V  +K   +A+++ 
Sbjct: 186 LSFPFLKEISVTTDLPTAFQNAHIAIVLDDFDQGGKEDAIGDMETKVSFYKRVAEAINQT 245

Query: 523 ARKDVKVLVVG-NPANTNALICSKYAPSIPKENFTAMTRLDQ 645
           A KD++VLV G  P N+   I   + PSIP++N  A+ ++ +
Sbjct: 246 ASKDIRVLVAGTGPLNSLVSILIDHTPSIPRQNIAAVAQVKE 287


>UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella
           chejuensis KCTC 2396|Rep: Malate dehydrogenase - Hahella
           chejuensis (strain KCTC 2396)
          Length = 193

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 36/64 (56%), Positives = 42/64 (65%)
 Frame = +1

Query: 451 MERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 630
           M+R   L  N  IF EQG+AL KVA+  VK LVVGNPANTNALI    A  +P   F+A+
Sbjct: 1   MDRMQQLQENPSIFVEQGKALGKVAKDTVKTLVVGNPANTNALIAWANARYLPHHQFSAL 60

Query: 631 TRLD 642
            RLD
Sbjct: 61  MRLD 64


>UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 553

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 3/165 (1%)
 Frame = +1

Query: 160 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 339
           +  + P++V +T ++  IAY ++ +IA G V G    V + LL        +EG  ME+ 
Sbjct: 120 LSRSTPLQVCITNSSSPIAYHMVNEIARGDVLGHDNEVSIRLLTKPEDKDYVEGQCMEVF 179

Query: 340 DCALPLLAGVLPTANPEEAFKDVAAAFLVG--AMPRKEGMERKDLLAANVRIFKEQGQAL 513
           D A PLL GV    +   A   V  A  +    +  +E  +   +       F   G+ L
Sbjct: 180 DLACPLLRGVKVYTDATAALTGVHVAVFLDEFCLMEEENAKLGGVSQEGCAQFALYGRIL 239

Query: 514 DKVARKDVKVLVVG-NPANTNALICSKYAPSIPKENFTAMTRLDQ 645
           ++ A +DVKVL+ G    N +AL+    AP I ++N     RL +
Sbjct: 240 NQYAEQDVKVLIGGRGKLNFSALMLKHNAPRIARQNIIITPRLQE 284


>UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21;
           Amniota|Rep: Malate dehydrogenase 1B - Homo sapiens
           (Human)
          Length = 518

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
 Frame = +1

Query: 175 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 354
           P++V +T A+    Y+L+  + SG VFG    + + L D       L+ +V+E  D A P
Sbjct: 131 PLQVWITSASAPACYNLIPILTSGEVFGMHTEISITLFDNKQAEEHLKSLVVETQDLASP 190

Query: 355 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKD 534
           +L  V      EEAF+      ++     KE    +D L + V + +  G  ++K A + 
Sbjct: 191 VLRSVSICTKVEEAFRQAHVIVVLDDSTNKEVFTLEDCLRSRVPLCRLYGYLIEKNAHES 250

Query: 535 VKVLVVGNP-ANTNALICSKYAPSI 606
           V+V+V G    N   ++  +YAP I
Sbjct: 251 VRVIVGGRTFVNLKTVLLMRYAPRI 275


>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
           Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 334

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 48/154 (31%), Positives = 70/154 (45%)
 Frame = +1

Query: 181 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 360
           ++ + GAAG I  S + Q A+     P     L L D  P    LEGV  E+  C    L
Sbjct: 8   KLTIVGAAGMIG-SNMAQTAAMMRLTPN----LCLYD--PFAVGLEGVAEEIRHCGFEGL 60

Query: 361 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVK 540
             +  T++ +EA  D       G  PRKEGM R+DLL  N  I  + G+ +         
Sbjct: 61  -NLTFTSDIKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKH 119

Query: 541 VLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
           V+++ NPA+   L+   Y+   P +  T +  LD
Sbjct: 120 VIIIFNPADITGLVTLIYSGLKPSQ-VTTLAGLD 152


>UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep:
           Zgc:153922 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 447

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 1/159 (0%)
 Frame = +1

Query: 160 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 339
           +K   P+ + ++ A   + YSL+  + +  +F     + LHL+D +    +L+ + ME  
Sbjct: 126 LKSLRPLHIWISSALNPVCYSLIPHLFTPGLFSGLPILSLHLMDTSGSEEMLQALKMETV 185

Query: 340 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 519
           D A+P L       N E+  KD  A                         F   GQ ++ 
Sbjct: 186 DLAIPRLHEPAGEYNDEQNDKDQVAEH-----------------------FHRYGQLIET 222

Query: 520 VARKDVKVLVVGN-PANTNALICSKYAPSIPKENFTAMT 633
            A+KDV+VLV G+   N    +  + APSI   NF AMT
Sbjct: 223 NAQKDVRVLVAGDFFINMKCSLLIENAPSIDSRNFVAMT 261


>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
           Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
           fragilis
          Length = 333

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 49/146 (33%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
 Frame = +1

Query: 181 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 360
           ++ + GAAG I  S + Q A      P     + L D  P    LEGV  EL  CA   +
Sbjct: 8   KLTIVGAAGMIG-SNMAQTALMMKLTPN----ICLYD--PYAPALEGVAEELYHCAFEGV 60

Query: 361 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVK 540
             +  T++ +EA          G   RK GM R+DLL  N  I  + G+ + +    DVK
Sbjct: 61  -NLTYTSDIKEALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYC-PDVK 118

Query: 541 -VLVVGNPANTNALICSKYAPSIPKE 615
            V+VV NPA+   LI   YA   P +
Sbjct: 119 HVVVVFNPADITGLIVLLYAGLKPSQ 144


>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
           cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
           Kluyveromyces lactis|Rep: Similar to sp|P22133
           Saccharomyces cerevisiae YOL126c MDH2 malate
           dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 404

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 7/145 (4%)
 Frame = +1

Query: 157 NIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHL-LDIAPM-MGVLEGVVM 330
           N +  E +++ V GAAG I  SL   + S A F        H+ L +  +    + G   
Sbjct: 40  NAQEKEILKISVLGAAGGIGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAA 99

Query: 331 ELADCALPLLAGV-LP---TANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKE 498
           +L+    P+      P        +   + +   +   +PRK GM R DL+  N +I K 
Sbjct: 100 DLSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKS 159

Query: 499 QGQALDKVA-RKDVKVLVVGNPANT 570
            G+ + K      V VLV+ NP N+
Sbjct: 160 LGEDIAKYCDLNKVHVLVISNPINS 184


>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
           precursor; n=41; cellular organisms|Rep: Malate
           dehydrogenase, chloroplast precursor - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 403

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 3/150 (2%)
 Frame = +1

Query: 151 YGNIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVM 330
           YG  K+    +V V GAAG I   L   I    +        LHL DIA +    +GV  
Sbjct: 75  YG-FKINASYKVAVLGAAGGIGQPLSLLIKMSPLVST-----LHLYDIANV----KGVAA 124

Query: 331 ELADCALPLLAGVLPTANPEE---AFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQ 501
           +L+ C  P  + V     P E     KDV    +   +PRK GM R DL   N  I K  
Sbjct: 125 DLSHCNTP--SQVRDFTGPSELADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTL 182

Query: 502 GQALDKVARKDVKVLVVGNPANTNALICSK 591
            +A+ +    +  + ++ NP N+   I ++
Sbjct: 183 VEAVAENC-PNAFIHIISNPVNSTVPIAAE 211


>UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to
            tetratricopeptide repeat domain 21B; n=1; Apis
            mellifera|Rep: PREDICTED: similar to tetratricopeptide
            repeat domain 21B - Apis mellifera
          Length = 1491

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 32/93 (34%), Positives = 48/93 (51%)
 Frame = +1

Query: 151  YGNIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVM 330
            Y  IK  E +  +VT    +IA S LY+I +  VFG  Q VF+ L +++     LE + +
Sbjct: 1214 YPRIKK-EILEKLVTDGTTEIARSFLYRILTDDVFGKNQCVFVSLYELSTKTMFLESLAI 1272

Query: 331  ELADCALPLLAGVLPTANPEEAFKDVAAAFLVG 429
            EL   +  LL+G+  + N  E FKD      +G
Sbjct: 1273 ELYSFSPKLLSGISYSNNVFE-FKDADVVICIG 1304


>UniRef50_A2Q2G7 Cluster: Putative uncharacterized protein; n=1;
           Medicago truncatula|Rep: Putative uncharacterized
           protein - Medicago truncatula (Barrel medic)
          Length = 165

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 27/62 (43%), Positives = 34/62 (54%)
 Frame = +1

Query: 205 GQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTAN 384
           GQI  +L   IA G + G  Q V LH+LDI P +  L+GV MEL D  +     V  +AN
Sbjct: 24  GQIGDALAPMIARGMMLGTNQHVILHMLDIEPTLEALKGVKMELIDVDVAAAGYVDKSAN 83

Query: 385 PE 390
            E
Sbjct: 84  IE 85


>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
           ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 381

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 46/141 (32%), Positives = 69/141 (48%), Gaps = 10/141 (7%)
 Frame = +1

Query: 178 IRVVVTGAAGQIAY--SLLYQIASGAVFGPQQPVF-LHLLDIAPMMGVLEGVVMELADCA 348
           +RV V GAAG I    SLL +     V G       L L D+A     L GV  +L+   
Sbjct: 24  VRVAVLGAAGGIGQPLSLLLKTQLAQVLGDANASLELALYDVAA--DALAGVAADLSHVN 81

Query: 349 LPL-LAGVLPTANP-EEAFKDV---AAAFLVGA-MPRKEGMERKDLLAANVRIFKEQGQA 510
            P+ ++  +P++   EEA ++    A+  ++ A +PRK GM R DL+  N  I K   + 
Sbjct: 82  TPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKG 141

Query: 511 LDKVA-RKDVKVLVVGNPANT 570
           +      + V VLV+ NP N+
Sbjct: 142 IAGACDLEKVFVLVISNPVNS 162


>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
           aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
          Length = 334

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/60 (38%), Positives = 35/60 (58%)
 Frame = +1

Query: 391 EAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANT 570
           E  K      +   +PR+EGM R+DLL  N++I K+   A+ + A KD  ++VV NP +T
Sbjct: 84  EELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYA-KDSIIIVVSNPVDT 142


>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: L-lactate
           dehydrogenase precursor - Methanoregula boonei (strain
           6A8)
          Length = 332

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = +1

Query: 394 AFKDVAAAFLV---GAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPA 564
           + KDVA + +V      PR  G  R DL   N RI     + +  +A  D K+++V NP 
Sbjct: 67  SLKDVAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIA-PDTKIIMVTNPV 125

Query: 565 NTNALICSKYAPSIPKENFTAMTRLD 642
           +    +  KY+   P + F   T LD
Sbjct: 126 DVMTCVALKYSGLKPNQVFGLGTHLD 151


>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
           Malate dehydrogenase - Plasmodium falciparum
          Length = 313

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 2/120 (1%)
 Frame = +1

Query: 277 LHLLDIAPMMGVLEGVVMELADCA--LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 450
           L L D+ P  G+ +G  ++L   +  L +   +L T N  E  KD     +   + RKEG
Sbjct: 28  LILYDVVP--GIPQGKALDLKHFSTILGVNRNILGT-NQIEDIKDADIIVITAGVQRKEG 84

Query: 451 MERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 630
           M R+DL+  N +I K   +++ K+      V+ V NP +    +  K++ ++P E    M
Sbjct: 85  MTREDLIGVNGKIMKSVAESV-KLHCSKAFVICVSNPLDIMVNVFHKFS-NLPHEKICGM 142


>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
           domain protein; n=2; Campylobacter|Rep: Lactate/malate
           dehydrogenase, NAD binding domain protein -
           Campylobacter curvus 525.92
          Length = 297

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 3/143 (2%)
 Frame = +1

Query: 178 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 357
           +++ V GA G +  S+ Y +A   V        + L+DI   +   + + +  A C   +
Sbjct: 1   MKISVIGA-GNVGASIAYALAMRGVCDE-----IALVDIFGDVARAKAIDIAQAGC---V 51

Query: 358 LAGVLPTANPEEAFKDVAAAFLV---GAMPRKEGMERKDLLAANVRIFKEQGQALDKVAR 528
             G L TA  ++ F  + A+ +V      PRKEG  R+DLL  N ++ K+  Q + K A 
Sbjct: 52  FCGCLSTAGGDD-FALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAP 110

Query: 529 KDVKVLVVGNPANTNALICSKYA 597
             + V++V NP +       +Y+
Sbjct: 111 NAI-VIIVTNPLDVMVWTVLRYS 132


>UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein
           NCU04826.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU04826.1 - Neurospora crassa
          Length = 1422

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/83 (30%), Positives = 37/83 (44%)
 Frame = -3

Query: 554 PTTRTFTSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAV 375
           PTT   T+  +  ++     +  ++  A R   ++PS  G +PT+ +A  S   SS  A 
Sbjct: 160 PTTAASTTTASHRTRPSSSEIDSKSTTASRRTSAVPSSTGASPTKPSARVSSTTSSTTAA 219

Query: 374 GRTPAKSGRAQSANSMTTPSSTP 306
            R PA S       S T  S TP
Sbjct: 220 ARKPASSSTVSPRTSTTGVSRTP 242


>UniRef50_A0T7L1 Cluster: Putative uncharacterized protein; n=1;
           Burkholderia ambifaria MC40-6|Rep: Putative
           uncharacterized protein - Burkholderia ambifaria MC40-6
          Length = 543

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 31/155 (20%), Positives = 68/155 (43%)
 Frame = -2

Query: 645 LIETSHGSEIFFWNRWSILRTY*SICIGWVANNKDLHIFTSHFVQSLALLFEDAHISSKK 466
           ++E  H  E+        L     + +  VA+++ LH+    FVQ  AL  ED  +  ++
Sbjct: 383 VVEAQHCGEVLLRQIRCRLHGDVRVGVRRVADDQHLHVAARDFVQRGALDREDLGVRRQQ 442

Query: 465 ILPLHTFLSGHXXXXXXXXXXXXXXFRICCRKNPSQKWQSTVSQLHDNTFKYTHHRRNIK 286
           +L  H   +                 RI    +  ++ +  + +LH + F      R ++
Sbjct: 443 VLAFHALRARTCADQQSDVCILECHLRIVGDHDAREQRERAIVELHHDAFDGGLGLREVE 502

Query: 285 KVEEDRLLRSKNCSRRNLIKK*VCNLSGSTSYNNS 181
           ++++DRL+ ++  + R+  ++ VC+L+      N+
Sbjct: 503 QLQDDRLVLAEQVAVRDAEQQGVCDLTCGAGDGNA 537


>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
           Actinomycetales|Rep: Lactate/malate dehydrogenase -
           Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 330

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 22/57 (38%), Positives = 29/57 (50%)
 Frame = +1

Query: 391 EAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNP 561
           E   D +   +   +PRK GM R DLL  N RI +   + + K A   V V+VV NP
Sbjct: 83  EVIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAV-VIVVSNP 138


>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
           Malate dehydrogenase 1 - Aquifex aeolicus
          Length = 335

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 26/88 (29%), Positives = 37/88 (42%)
 Frame = +1

Query: 367 VLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVL 546
           V P     E  +      +    PR+ GM R+DLL AN+RI       + + A  D  V+
Sbjct: 73  VTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIADRIKRYA-PDAIVI 131

Query: 547 VVGNPANTNALICSKYAPSIPKENFTAM 630
           VV NP +    +  K   + PK     M
Sbjct: 132 VVTNPVDVMTYVAYKLL-NFPKNRVMGM 158


>UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD
           (soluble); n=1; Takifugu rubripes|Rep: malate
           dehydrogenase 1B, NAD (soluble) - Takifugu rubripes
          Length = 441

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 8/159 (5%)
 Frame = +1

Query: 190 VTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGV 369
           ++ A    +  L+  + S  VF     + +HLLD+     VL  +  EL   AL LL  V
Sbjct: 122 ISSALSSTSQFLMSSLISADVFPNISTIDVHLLDLDGDEEVLHHLKNELEHQALHLLHQV 181

Query: 370 LPTANPEEAFKDVAAAFLVGAM------PRKEGMERKDLLAANVRIFKEQGQALDKVARK 531
               + E+AF+      L+  +         E   +K  + A    ++E G+ +D   +K
Sbjct: 182 TIHTDLEQAFQKADVIILLDELWCDDIATVDERELKKQKIDAISERYREYGRLIDTQTKK 241

Query: 532 DVKVLVVGNP-ANTNALICSKYAPSIPKENFTAM-TRLD 642
           +VKV+V G    N    +   Y  SI      A+ T+L+
Sbjct: 242 EVKVIVSGESFVNLRCSLLLDYTHSIHSHQIVALATQLE 280


>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
           Toxoplasma gondii|Rep: Mitochondrial
           malate-dehydrogenase - Toxoplasma gondii
          Length = 470

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 21/68 (30%), Positives = 33/68 (48%)
 Frame = +1

Query: 379 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGN 558
           +N     KD     +   +PRK GM R DLLA N +I  + G+A+ +    +  V+ + N
Sbjct: 217 SNDYSVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYC-PNAFVICITN 275

Query: 559 PANTNALI 582
           P +    I
Sbjct: 276 PLDVMVYI 283


>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
           organisms|Rep: Malate dehydrogenase - Silicibacter
           pomeroyi
          Length = 320

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
 Frame = +1

Query: 166 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 345
           MA P ++ + GA GQI  +L + +A   +        + L DIA   G  EG  +++A+ 
Sbjct: 1   MARP-KIALIGA-GQIGGTLAHLVALKELGD------VVLFDIAE--GTPEGKALDIAES 50

Query: 346 ALPLLAGVLPTANPEEAFKDVAAA---FLVGAMPRKEGMERKDLLAANVRIFKEQGQALD 516
                 G        +++ D+A A    +   +PRK GM R DLL  N+++ K  G+ + 
Sbjct: 51  GPS--EGFDAKLKGTQSYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIR 108

Query: 517 KVARKDVKVLVVGNP 561
             A  D  V+ + NP
Sbjct: 109 DNA-PDAFVICITNP 122


>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
           hepaticus|Rep: Malate dehydrogenase - Helicobacter
           hepaticus
          Length = 315

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 33/150 (22%), Positives = 62/150 (41%)
 Frame = +1

Query: 181 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 360
           ++ + G +G +   + +    GA+    + + L   DI    GV   +    A   +P+L
Sbjct: 4   KIAIIGGSGNVGSHIAFL---GAMRHIAKEILLFSNDIPRCKGVGLDISQAAAIFDIPIL 60

Query: 361 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVK 540
              +   N  E   +     +    PR   M R DLL  N  I +E    + ++A + + 
Sbjct: 61  ---IKGCNSYEEIAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSL- 116

Query: 541 VLVVGNPANTNALICSKYAPSIPKENFTAM 630
           ++VV NP +   L+  +++    KE    M
Sbjct: 117 LIVVSNPLDAMCLVAKQWS-KFEKERVIGM 145


>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
           Malate dehydrogenase - Brucella melitensis
          Length = 320

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 22/84 (26%), Positives = 38/84 (45%)
 Frame = +1

Query: 379 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGN 558
           AN   A +      +   +PRK GM R DLL  N+++ ++ G  + K A  +  V+ + N
Sbjct: 63  ANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYA-PEAFVICITN 121

Query: 559 PANTNALICSKYAPSIPKENFTAM 630
           P +       K++  +P      M
Sbjct: 122 PLDAMVWALQKFS-GLPAHKVVGM 144


>UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 323

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 40/146 (27%), Positives = 61/146 (41%), Gaps = 3/146 (2%)
 Frame = +1

Query: 169 AEPIRVVVTGAA---GQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 339
           ++P++VV+ GA       AY+LL   A+  +          L+D+       EG VM+L 
Sbjct: 10  SKPVKVVIVGAGYVGSTTAYTLLMNRAAAEIV---------LIDVDK--DKTEGEVMDLV 58

Query: 340 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 519
             A P L      A   E  K  +   L     +K G  R +L  +N  IFKE    + +
Sbjct: 59  HAA-PFLHQTRIWAGDYEDCKGASVIILTAGANQKPGQSRMELAQSNWGIFKEIVPKVVQ 117

Query: 520 VARKDVKVLVVGNPANTNALICSKYA 597
            A  D  +LV  NP +       K++
Sbjct: 118 HASPDALLLVSANPVDVMTYAAVKFS 143


>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
           Methanomicrobiales|Rep: L-lactate dehydrogenase -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 319

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 24/74 (32%), Positives = 36/74 (48%)
 Frame = +1

Query: 421 LVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNALICSKYAP 600
           L   +PRK    R DL   N RI K   + + ++A + + +LVV NP +    +  KY+ 
Sbjct: 79  LTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAI-LLVVTNPVDIMTTVALKYSG 137

Query: 601 SIPKENFTAMTRLD 642
            +P   F   T LD
Sbjct: 138 MMPHRVFGLGTHLD 151


>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
           Ascomycota|Rep: Probable L-lactate dehydrogenase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 330

 Score = 39.1 bits (87), Expect = 0.090
 Identities = 29/84 (34%), Positives = 38/84 (45%)
 Frame = +1

Query: 316 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFK 495
           EG  M+L   A PL           +  KD  A  +     +K G  R DLL AN+ IFK
Sbjct: 59  EGEAMDLNHAA-PLSHETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFK 117

Query: 496 EQGQALDKVARKDVKVLVVGNPAN 567
           E  + + K   KD  +LV  NP +
Sbjct: 118 EILREVTKYT-KDAILLVATNPVD 140


>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
           Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
           (NAD) - Ignicoccus hospitalis KIN4/I
          Length = 311

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
 Frame = +1

Query: 175 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 354
           P +V V G  G++  +  Y +A   V G  + V   L+D  P  G+ +GV+ ++   A  
Sbjct: 5   PYKVAVIGT-GRVGATFAYTMA--IVPGVARMV---LVDAVP--GLSKGVMEDIKHAAAV 56

Query: 355 LLAGVLPTANPEEAFKDVAAAFLVGA-MPRKEGMERKDLLAANVRIFKEQGQALDKVARK 531
               +   A  + +  + A A ++ A  PRK  M R+DL   N +I ++ G  L +    
Sbjct: 57  FRRSIQVEAYDDVSKVENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKL-RDRNP 115

Query: 532 DVKVLVVGNPANTNALICS 588
               +V+ NP +   +I S
Sbjct: 116 GAFYMVITNPVDVMTMILS 134


>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
           Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
           acidocaldarius
          Length = 306

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 28/105 (26%), Positives = 45/105 (42%)
 Frame = +1

Query: 283 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 462
           L D+ P +       +  A  AL +   +L T N ++         +    PRK GM R+
Sbjct: 31  LYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDD-ISGADIVVITAGKPRKPGMSRR 89

Query: 463 DLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNALICSKYA 597
           DL   N +I  +  + L K   K    ++V NP +  A +  KY+
Sbjct: 90  DLFIDNAKIMIDLAKKLPK-KNKGAMYIMVANPVDMMASVFMKYS 133


>UniRef50_Q9HHJ2 Cluster: Vng6368h; n=1; Halobacterium
           salinarum|Rep: Vng6368h - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 141

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = -3

Query: 554 PTTRTFTSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAA-TSLKASSGFA 378
           PT   F   RA++ +         T + +RS  S P+     P+  + A     AS+   
Sbjct: 3   PTMPRFPCSRASMMERSRKLSSSTTYSRKRSTASRPTPATTQPSTSSIAWKKTPASTSTH 62

Query: 377 VGRTPAKSGRAQSANSMTTPSSTPIIGAISR 285
              TP++ GR  SAN   +PSSTP +  I +
Sbjct: 63  SPPTPSRQGRPSSANRNRSPSSTPALSRICK 93


>UniRef50_O97299 Cluster: Putative uncharacterized protein
           MAL3P7.37; n=1; Plasmodium falciparum 3D7|Rep: Putative
           uncharacterized protein MAL3P7.37 - Plasmodium
           falciparum (isolate 3D7)
          Length = 1542

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 5/60 (8%)
 Frame = -2

Query: 330 HDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VC---NLSGSTSYN--NSDRFSH 166
           HDN + Y H  +N K  E +R+ + K   ++N  +K V    N  G+ +YN  N+D F +
Sbjct: 204 HDNNYNYFHVGKNEKMKERERINKKKKIGKKNNRRKHVLRKNNTDGNNNYNDDNNDSFDN 263


>UniRef50_A3KPA8 Cluster: LOC568298 protein; n=2; Danio rerio|Rep:
           LOC568298 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 258

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
 Frame = -3

Query: 554 PTTRT-FTSLRATLSKAWPCSLKMRTLAARRSFL--SIPSFLGIAPTRKAAATSLKASSG 384
           PTT+T F S   T S  +P S   + LAA + F   +  +  G +P     A S  A + 
Sbjct: 25  PTTQTTFGSSTFTTSSNFPASTP-QALAAPKPFAFGAAGASSGASPFTFGTAASTSAPA- 82

Query: 383 FAVGRTPAKSGRAQ--SANSMTTPSSTPIIGAISR 285
           F     PA  G +   S  + TTPS+TP+ GA ++
Sbjct: 83  FGTNSQPAFGGVSSGFSFGNTTTPSATPVFGATTQ 117


>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 312

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
 Frame = +1

Query: 328 MELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQ 507
           M++AD      + V+         KD     +   +PR  G  R D+L  +V   ++   
Sbjct: 47  MDIADSVSFFNSSVIVRCGDYSDCKDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVS 106

Query: 508 ALDKVARKDVKVLVVGNPANTNALICSKYAPSIPKEN-FTAMTRLD 642
            L+K+  K + ++ + NPA+  A    K A  +PK   F+  T LD
Sbjct: 107 NLNKIEIKGI-IITITNPADIIADFVRK-ATGLPKNRVFSTGTSLD 150


>UniRef50_Q6DXR3 Cluster: Predicted protein; n=3; eurosids II|Rep:
           Predicted protein - Gossypium hirsutum (Upland cotton)
           (Gossypium mexicanum)
          Length = 253

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
 Frame = +1

Query: 283 LLDIAPMMGVLEGV--VMELADCA-LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGM 453
           L+++A + GVL G+  VM+ ADC  L  L GVL   NP ++   +A   ++    RK G 
Sbjct: 173 LVEVA-LKGVLAGLERVMKAADCVRLKALKGVLDVLNPSQSLDFLAGICMLQIQIRKWGQ 231

Query: 454 ERKDLLAANVRIFKE 498
            R +   +N  I  E
Sbjct: 232 NRDNQKGSNPIILGE 246


>UniRef50_Q54HN9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 621

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 33/117 (28%), Positives = 49/117 (41%)
 Frame = -3

Query: 536 TSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAK 357
           TS+  T    W  + K   L    + +S P+     P   A  +++ ASS      TP  
Sbjct: 469 TSVVETKKMEWGPADKKSVLPVETTVVSPPTTTTTTPV--APTSNVAASSSSTATATPTT 526

Query: 356 SGRAQSANSMTTPSSTPIIGAISRRWRKTGC*GPKTAPDAI**RSEYAICPAAPVTT 186
           +   Q+A S   PS+       S+         PK +P  +  +S+ A  PAAPVTT
Sbjct: 527 TTTTQTAASTNAPSNKKSTTQSSQ---------PKKSPSKVEDKSKTAPTPAAPVTT 574


>UniRef50_P19980 Cluster: Malate dehydrogenase; n=5; Bacteria|Rep:
           Malate dehydrogenase - Phenylobacterium immobile
          Length = 25

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 16/22 (72%), Positives = 18/22 (81%)
 Frame = +1

Query: 175 PIRVVVTGAAGQIAYSLLYQIA 240
           PIRV VTGAAG I Y LL++IA
Sbjct: 4   PIRVAVTGAAGNIGYHLLFRIA 25


>UniRef50_A7P2B9 Cluster: Chromosome chr1 scaffold_5, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_5, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 199

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/53 (35%), Positives = 25/53 (47%)
 Frame = +1

Query: 184 VVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           +V  G  G  +      IA     G  QP+ LH+LDI P   VL G V+ + D
Sbjct: 101 LVAVGMGGGTSSGEAPMIARRGRLGADQPMILHMLDIPPAAEVLNGGVVAITD 153



 Score = 33.5 bits (73), Expect = 4.5
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = +1

Query: 235 IASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 342
           IA     G  QP+ LH+LDI P   VL G V+ + D
Sbjct: 13  IARRGRLGADQPMILHMLDIPPAAEVLNGGVVAITD 48


>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
           Methanobacteriaceae|Rep: Malate dehydrogenase -
           Methanobacterium thermoautotrophicum
          Length = 325

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
 Frame = +1

Query: 277 LHLLDIAPMMGVLEGVVMELADC--ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 450
           LHL+     +    G V++++D   A  +   +  +A+ E  +         G +PR   
Sbjct: 29  LHLISRKESLEQNLGEVLDMSDALAAKGVSVKLENSADIENVYGSRIVVITAG-VPRTAD 87

Query: 451 MERKDLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 630
           M+R DL   N RI  +  + + + A  D  +LVV NP +    +  +Y+   P   F   
Sbjct: 88  MDRDDLAFKNGRIVADYARQIARFA-PDSIILVVTNPVDVMTYVALRYSGFHPSRVFGLG 146

Query: 631 TRLD 642
             LD
Sbjct: 147 NHLD 150


>UniRef50_Q88SJ4 Cluster: Extracellular protein,
           gamma-D-glutamate-meso-diaminopimelate muropeptidase;
           n=1; Lactobacillus plantarum|Rep: Extracellular protein,
           gamma-D-glutamate-meso-diaminopimelate muropeptidase -
           Lactobacillus plantarum
          Length = 370

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 21/88 (23%), Positives = 42/88 (47%)
 Frame = -3

Query: 551 TTRTFTSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVG 372
           T+   TS   T + +   ++   ++AA+ S  S  S   +  +   ++ + +ASS     
Sbjct: 123 TSAAATSSSTTSASSTSQAVSSSSVAAQSSSTSTASASSVTSSASTSSVASQASSSAVTS 182

Query: 371 RTPAKSGRAQSANSMTTPSSTPIIGAIS 288
              ++S  +QS+ S  + SSTP+  + S
Sbjct: 183 SATSQSSASQSSASQASQSSTPVASSTS 210


>UniRef50_A6W575 Cluster: Putative uncharacterized protein; n=1;
           Kineococcus radiotolerans SRS30216|Rep: Putative
           uncharacterized protein - Kineococcus radiotolerans
           SRS30216
          Length = 212

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
 Frame = -3

Query: 563 AGLPTTRTFTSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSL--KAS 390
           A  P  +T    + T S A     +  T  A+++    P+     P +K  A     K +
Sbjct: 71  AAAPAKKTSAPAQKTASSA---PAQKATTPAQKTASPAPAQKATTPAKKTTAKKAAGKKA 127

Query: 389 SGFAVGRTPAKSGRAQSANS--MTTPSSTPIIGAISRRWRKTGC*GPKTAPDAI**R--- 225
           +   V  TPA +  A +A +  + TP++TP   A +++  K        A DA   R   
Sbjct: 128 APAPVEETPAPAAEAPAAEAPAVETPAATPAKKATAKKAAKKSTPASTAAVDARAVREWA 187

Query: 224 --SEYAICPAAPVTTTLI 177
             +  A+ P  P++TT+I
Sbjct: 188 AANGIAVAPRGPISTTII 205


>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
           hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
           hyopneumoniae
          Length = 315

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 29/132 (21%), Positives = 56/132 (42%)
 Frame = +1

Query: 172 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 351
           +PI++ + GA G +  S LY   +  +          ++DI P     +G   +  D + 
Sbjct: 2   KPIKIALIGA-GNVGNSFLYAAMNQGLASEYG-----IIDINPDFA--DGNAFDFEDASA 53

Query: 352 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVARK 531
            L   +  +    +  KD     +    P+K G  R +L+A N+RI +E    + +    
Sbjct: 54  SLPFPISVSRYEYKDLKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFS 113

Query: 532 DVKVLVVGNPAN 567
            + + +V NP +
Sbjct: 114 GISI-IVANPVD 124


>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
           Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
           radiodurans
          Length = 304

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 24/88 (27%), Positives = 34/88 (38%)
 Frame = +1

Query: 346 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKVA 525
           A P+  G            D     L     +K G  R DLL  N  IF+E    + + A
Sbjct: 48  AAPVSHGTRVWHGGHSELADAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAA 107

Query: 526 RKDVKVLVVGNPANTNALICSKYAPSIP 609
             D  +LV  NP +    + ++ AP  P
Sbjct: 108 -PDAVLLVTSNPVDLLTDLATQLAPGQP 134


>UniRef50_A3BI71 Cluster: Putative uncharacterized protein; n=7;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 571

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 15/24 (62%), Positives = 16/24 (66%)
 Frame = +3

Query: 306 GCT*RCCHGVG*LCSATFGWGSSY 377
           GC   CC GVG + S T GWGSSY
Sbjct: 539 GCGGGCCGGVGFVESPTCGWGSSY 562


>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
           oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
           (Rhizopus delemar)
          Length = 320

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 31/120 (25%), Positives = 53/120 (44%)
 Frame = +1

Query: 283 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 462
           ++D+ P   +++  V++LAD A  +    +   + EEA +        GA  R EG  R 
Sbjct: 34  IVDVNP--DIVQAQVLDLADAA-SISHTPIRAGSAEEAGQADIVVITAGAKQR-EGEPRT 89

Query: 463 DLLAANVRIFKEQGQALDKVARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 642
            L+  N R+ +     +  + R D  +LVV NP +    I    +   P +   + T LD
Sbjct: 90  KLIERNFRVLQSIIGGMQPI-RPDAVILVVANPVDILTHIAKTLSGLPPNQVIGSGTYLD 148


>UniRef50_Q1J2E3 Cluster: Peptidase M23B precursor; n=1; Deinococcus
           geothermalis DSM 11300|Rep: Peptidase M23B precursor -
           Deinococcus geothermalis (strain DSM 11300)
          Length = 330

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 25/59 (42%), Positives = 33/59 (55%)
 Frame = -3

Query: 485 RTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSST 309
           RT+AAR     +PS  G+ P RK+AA+S       A  RTPA + RA S    + PS+T
Sbjct: 157 RTVAAR-----LPSSEGVTPDRKSAASS-------AARRTPAATVRAASIRVTSAPSAT 203


>UniRef50_Q869R4 Cluster: Similar to Streptococcus pneumoniae. Cell
            wall surface anchor family protein; n=3; Dictyostelium
            discoideum|Rep: Similar to Streptococcus pneumoniae. Cell
            wall surface anchor family protein - Dictyostelium
            discoideum (Slime mold)
          Length = 1806

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 23/61 (37%), Positives = 30/61 (49%)
 Frame = -3

Query: 425  TRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTPIIGAISRRWRKTGC*GPKTA 246
            T  AA T+  ++S F    TP+ S    S +S+TT  ST + GA S     TG  G  T 
Sbjct: 1220 TTTAATTATPSTSLFGSTTTPSTSS---STSSLTTTPSTGLFGASSSTTPSTGLFGSATT 1276

Query: 245  P 243
            P
Sbjct: 1277 P 1277


>UniRef50_Q8IEN1 Cluster: Putative uncharacterized protein MAL13P1.39;
            n=1; Plasmodium falciparum 3D7|Rep: Putative
            uncharacterized protein MAL13P1.39 - Plasmodium
            falciparum (isolate 3D7)
          Length = 6088

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 21/56 (37%), Positives = 28/56 (50%)
 Frame = -2

Query: 333  LHDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTSYNNSDRFSH 166
            L DN FK  + R NIKK+ E+R   SKN   +N  KK + N+     Y      S+
Sbjct: 1044 LQDNYFKKLYDR-NIKKMMEERENASKNIFAKNKKKKIILNILKKVYYRYEHNLSN 1098


>UniRef50_Q9P5T7 Cluster: Related to glucan 1, 4-alpha-glucosidase;
           n=2; Neurospora crassa|Rep: Related to glucan 1,
           4-alpha-glucosidase - Neurospora crassa
          Length = 701

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 28/93 (30%), Positives = 42/93 (45%)
 Frame = +1

Query: 331 ELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQA 510
           EL +C  P++     TA PE +    AAA    A  RKE M    +LA  V   + + +A
Sbjct: 383 ELEECGSPVVPW---TARPELSNAVAAAAAAAAAAERKEAMVGVPVLAVPVPPSRARTRA 439

Query: 511 LDKVARKDVKVLVVGNPANTNALICSKYAPSIP 609
             +   + V+ +V GN A   A   +   P +P
Sbjct: 440 --QTQAQSVQTVVTGNKAAAVAAAVALQIPQLP 470


>UniRef50_P58338 Cluster: Ornithine cyclodeaminase 1; n=34;
           Proteobacteria|Rep: Ornithine cyclodeaminase 1 -
           Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 329

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 5/109 (4%)
 Frame = -3

Query: 605 IDGAYLEHIR---AFVLAGLPTTRTFTSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLG 435
           +D  YL  +R   A  +A    +R  +S+ A         L++  LA  R       +  
Sbjct: 106 LDNGYLTDVRTAAAGAVAARRLSREDSSVAAVFGAGMQARLQLEALALVRPIREARIWAR 165

Query: 434 IAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSM--TTPSSTPIIGA 294
            A   +AAA +L    GFAV            A+ +  TTPS TP++ A
Sbjct: 166 DAAKAEAAAIALGGKLGFAVKAETDPRAAITGADIIVTTTPSETPVLKA 214


>UniRef50_Q9P5L4 Cluster: Related to DOS1 protein; n=3;
           Sordariomycetes|Rep: Related to DOS1 protein -
           Neurospora crassa
          Length = 452

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 18/59 (30%), Positives = 30/59 (50%)
 Frame = -3

Query: 470 RRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTPIIGA 294
           R + +S    L IA T+ AA+ +  ASSG     + + S  + S +  TTP++   + A
Sbjct: 90  RTTLISRTRALSIATTQAAASAAAAASSGVTAASSSSSSSSSASKDEQTTPTTVKDLSA 148


>UniRef50_Q8PTW7 Cluster: Putative uncharacterized protein; n=1;
           Methanosarcina mazei|Rep: Putative uncharacterized
           protein - Methanosarcina mazei (Methanosarcina frisia)
          Length = 324

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 7/108 (6%)
 Frame = +1

Query: 148 LYGNIKMAEPIRVVVTGAAGQIAYSLLYQIAS--GAVFGPQQPV----FLHLLDIAPMMG 309
           L GN+K+  P+ V+ +  A  + +  L +I +   AV    +PV    F  +L   P+  
Sbjct: 215 LLGNLKLLIPLGVIASALASLLYFRGLARIKAQTAAVLSLIEPVSSICFCCILLGEPLQS 274

Query: 310 -VLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 450
             + G ++ LA  AL   +  +    PE+ F+DV A F    MP + G
Sbjct: 275 NTVGGCLLILAGAALIGSSTSIQQGIPEKYFRDVWARFFQPYMPLRPG 322


>UniRef50_P35453 Cluster: Homeobox protein Hox-D13; n=47;
           Craniata|Rep: Homeobox protein Hox-D13 - Homo sapiens
           (Human)
          Length = 335

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
 Frame = -3

Query: 467 RSFLSIPSFLGI-----APTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTP 306
           R FLS P F G      A    AAA +  A+SGFA   T  ++G + S++S    ++ P
Sbjct: 33  RGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARP 91


>UniRef50_A7NQN6 Cluster: Extracellular solute-binding protein
           family 5 precursor; n=1; Roseiflexus castenholzii DSM
           13941|Rep: Extracellular solute-binding protein family 5
           precursor - Roseiflexus castenholzii DSM 13941
          Length = 564

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 15/111 (13%)
 Frame = +1

Query: 307 GVLEGVVMELADCALPLLAGVLPTANP--EEAFK---DVAAAFL--VGAMPRKEGMERKD 465
           G++E V   + + A   L+ V P   P  E+ ++   + AA  L   G +P  +G+  KD
Sbjct: 344 GIIESVYFNMVEPAYGPLSRVFPEYEPALEQMYEYNPEKAAQLLEEAGWLPGPDGVRVKD 403

Query: 466 LLAANVRIFKEQG--------QALDKVARKDVKVLVVGNPANTNALICSKY 594
                V I + +G        QA  +    D KVL    P+NT A+   KY
Sbjct: 404 GRRLEVTIVENKGWNDWVYVLQANLQAIGFDAKVLTTQGPSNTEAIASGKY 454


>UniRef50_Q7PWG9 Cluster: ENSANGP00000006494; n=2; cellular
            organisms|Rep: ENSANGP00000006494 - Anopheles gambiae
            str. PEST
          Length = 1721

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 23/89 (25%), Positives = 40/89 (44%)
 Frame = -3

Query: 575  AFVLAGLPTTRTFTSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLK 396
            +F  +G    ++ T   AT++   P +   +T A +    +  +   + P   A  ++  
Sbjct: 1263 SFASSGFGVAKSSTDTTATVAS--PATEPAKT-AGKEESTATATATTVTPASSATVSTPA 1319

Query: 395  ASSGFAVGRTPAKSGRAQSANSMTTPSST 309
            ASSG  V  T A      SA + TTP++T
Sbjct: 1320 ASSGTPVTATAAPVAATSSATTTTTPTTT 1348


>UniRef50_P20659 Cluster: Protein trithorax; n=4; Drosophila
           melanogaster|Rep: Protein trithorax - Drosophila
           melanogaster (Fruit fly)
          Length = 3726

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
 Frame = -3

Query: 497 SLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSAN-SMTT 321
           S   RT +A  S  S     G +P   + A+S  ASSG + G++ AKS  A S   + TT
Sbjct: 164 SKSSRTFSASTSVTSSGRSSGSSPDGNSGASSDGASSGISCGKSTAKSTEASSGKLAKTT 223

Query: 320 PSST 309
            + T
Sbjct: 224 GAGT 227


>UniRef50_UPI0000DD83F5 Cluster: PREDICTED: similar to keratin
           associated protein 9.2; n=1; Homo sapiens|Rep:
           PREDICTED: similar to keratin associated protein 9.2 -
           Homo sapiens
          Length = 301

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)
 Frame = +3

Query: 177 YQSCC-NWCCRTNCIL-TSLSNCVWSSFWTSATCLPP--PS*YCAYDGCT*RCC 326
           + +CC N CCRT C   T +++C   S  ++  C P    S  C    C   CC
Sbjct: 128 HPTCCQNTCCRTTCCQPTCVASCCQPSCCSTPCCQPTCCGSSCCGQTSCGTTCC 181


>UniRef50_Q4RJK7 Cluster: Chromosome 3 SCAF15037, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 3 SCAF15037, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 740

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 19/70 (27%), Positives = 30/70 (42%)
 Frame = +1

Query: 235 IASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAA 414
           +  G   GP     LH L +   +G  +G  + +   A P   GVL  ++P    ++  A
Sbjct: 220 VCGGVGLGPDHQERLHGLHVLRRVGADQGASLRMVQAAQPGGGGVLQRSHPRGGRREPGA 279

Query: 415 AFLVGAMPRK 444
           A  V  +P K
Sbjct: 280 AAEVRGLPVK 289


>UniRef50_Q2NDZ8 Cluster: Putative uncharacterized protein; n=1;
            Erythrobacter litoralis HTCC2594|Rep: Putative
            uncharacterized protein - Erythrobacter litoralis (strain
            HTCC2594)
          Length = 2409

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
 Frame = -3

Query: 617  FSFGIDGAYLEHIRAFVLAGLPT-TRTFTSLRATLS-KAWPCSLKMRTLAARRSF-LSIP 447
            F  G+ GA+L   +  VL+G PT + + ++  A +S   +  SL   TLA  R + LS+ 
Sbjct: 1204 FQPGVAGAFLADTQGNVLSGAPTVSSSGSAANADVSGSPYTISLAQGTLATSRGYSLSLS 1263

Query: 446  SFLGIAPTRKAAATSLKASSGFAVGRT 366
                +  T KA   S+ A+S    G T
Sbjct: 1264 DAGRLTITPKAITASVSANSKTYDGTT 1290


>UniRef50_A7HYU6 Cluster: UspA domain protein; n=1; Parvibaculum
           lavamentivorans DS-1|Rep: UspA domain protein -
           Parvibaculum lavamentivorans DS-1
          Length = 289

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
 Frame = +1

Query: 286 LDIAPMMGVLEGVVMELADCALPLLAGVLPTAN--PEEAFKDVAAAFLVGAMPRKEGMER 459
           L  A  +G+L+G+ + L    LPL  G++  AN  P++    VA          +  +E 
Sbjct: 156 LRTARALGILDGLKVTLLHAFLPLAKGMMVYANVEPDKIADYVAHESSEAGQAIQTFIEG 215

Query: 460 KDLLAANVRIFKEQGQALDKVAR----KDVKVLVVGNPANTNA 576
            DL   +  +  E+G   D +AR    +   +L++G    T A
Sbjct: 216 LDLAPNDYELKLEEGAPFDVIARAVAERKADLLIIGTKGLTGA 258


>UniRef50_A6FWZ9 Cluster: L-lysine aminotransferase; n=1;
           Plesiocystis pacifica SIR-1|Rep: L-lysine
           aminotransferase - Plesiocystis pacifica SIR-1
          Length = 1013

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 23/74 (31%), Positives = 30/74 (40%)
 Frame = -3

Query: 593 YLEHIRAFVLAGLPTTRTFTSLRATLSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKA 414
           YLEH+RA +  G     T TS    + K   C    R    + + + +    G      A
Sbjct: 689 YLEHLRAILPRGTGHLYTTTSQDELVDKTLRCLKMSRDTPEQPATVCVGFEGGFVGHNTA 748

Query: 413 AATSLKASSGFAVG 372
           AA SL    GFA G
Sbjct: 749 AARSLSDPEGFAAG 762


>UniRef50_Q6BCL3 Cluster: Beta-1,4-endoglucanase precursor; n=5;
           Eukaryota|Rep: Beta-1,4-endoglucanase precursor -
           Bursaphelenchus xylophilus (Pinewood nematode worm)
          Length = 359

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 18/57 (31%), Positives = 28/57 (49%)
 Frame = -3

Query: 476 AARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTP 306
           AA     + PS    AP++ +AA S  +++       P+K+  A S  S T  S+TP
Sbjct: 62  AAPTKASAAPSTASAAPSKASAAPSTASAAPSTASAAPSKASAAPSTASSTASSTTP 118


>UniRef50_Q22MV0 Cluster: PWI domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: PWI domain containing
           protein - Tetrahymena thermophila SB210
          Length = 1085

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 20/62 (32%), Positives = 30/62 (48%)
 Frame = -2

Query: 360 QKWQSTVSQLHDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTSYNNS 181
           Q+ Q    Q+ DN      HR ++KK EED  L  K   ++ + KK     S S+S + S
Sbjct: 196 QQEQQNKDQIKDNKSNDKRHRESLKKFEEDEFLDKK--EKKEVEKKKNSRRSSSSSRSRS 253

Query: 180 DR 175
            +
Sbjct: 254 KK 255


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 625,080,632
Number of Sequences: 1657284
Number of extensions: 12403832
Number of successful extensions: 41339
Number of sequences better than 10.0: 89
Number of HSP's better than 10.0 without gapping: 39392
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41249
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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