Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV10j22r
(709 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 217 2e-56
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 217 2e-56
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 217 2e-56
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 217 2e-56
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 217 2e-56
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 217 3e-56
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 213 4e-55
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 180 6e-45
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 180 6e-45
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 180 6e-45
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 176 6e-44
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 155 1e-43
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 144 3e-34
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 144 4e-34
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 104 3e-22
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 100 1e-20
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 100 1e-20
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 1e-20
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 100 1e-20
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 1e-20
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 1e-20
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 1e-20
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 97 7e-20
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 97 7e-20
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 97 7e-20
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 96 9e-20
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 95 2e-19
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 95 2e-19
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 95 2e-19
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 95 2e-19
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 95 3e-19
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 95 3e-19
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 90 8e-18
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 90 8e-18
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 81 4e-15
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 81 5e-15
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 80 7e-15
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 80 7e-15
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 80 7e-15
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 79 2e-14
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 79 2e-14
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 79 2e-14
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 79 2e-14
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 79 2e-14
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 79 2e-14
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 79 2e-14
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 79 2e-14
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 77 8e-14
DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retin... 63 1e-12
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 70 9e-12
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 70 9e-12
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 69 2e-11
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 69 2e-11
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 69 2e-11
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 69 2e-11
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 67 5e-11
AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retin... 63 1e-09
AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retin... 63 1e-09
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 63 1e-09
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 62 2e-09
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 60 6e-09
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 58 2e-08
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 58 2e-08
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 58 2e-08
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 58 2e-08
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 58 2e-08
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 55 2e-07
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 52 2e-06
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 52 2e-06
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 52 2e-06
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 52 2e-06
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 52 2e-06
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 52 2e-06
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 51 4e-06
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 51 4e-06
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 51 4e-06
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 50 8e-06
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 50 8e-06
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 50 1e-05
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 49 1e-05
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 48 2e-05
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 48 2e-05
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 48 2e-05
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 48 2e-05
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 48 2e-05
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 48 2e-05
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 48 2e-05
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 48 2e-05
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 48 4e-05
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 47 6e-05
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 47 6e-05
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 47 6e-05
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 47 6e-05
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 47 6e-05
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 47 6e-05
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 47 6e-05
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 46 1e-04
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 46 1e-04
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 42 0.002
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 42 0.002
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 42 0.002
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 42 0.002
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 42 0.002
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 42 0.002
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 41 0.005
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 41 0.005
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 41 0.005
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 40 0.007
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 40 0.007
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 40 0.007
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 39 0.015
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 39 0.015
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 39 0.015
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 39 0.020
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 39 0.020
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 39 0.020
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 39 0.020
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 37 0.081
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 37 0.081
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.081
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.081
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.081
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.081
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 35 0.25
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 35 0.25
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.25
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.25
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 35 0.25
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 35 0.25
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.25
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.25
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 33 0.76
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 33 0.76
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 33 0.76
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 33 1.3
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 33 1.3
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 33 1.3
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 33 1.3
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 33 1.3
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 33 1.3
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 33 1.3
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 33 1.3
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 33 1.3
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 32 1.7
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 32 1.7
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 32 1.7
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 32 1.7
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 32 1.7
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 32 1.7
Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein. 32 2.3
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 31 4.0
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 31 5.3
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 31 5.3
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 31 5.3
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 31 5.3
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 31 5.3
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 31 5.3
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 31 5.3
AJ272137-1|CAC03490.1| 562|Homo sapiens membrane type matrix me... 30 9.3
AJ239053-1|CAB94713.1| 562|Homo sapiens membrane-type matrix me... 30 9.3
AJ003147-1|CAA05902.1| 183|Homo sapiens metalloproteinase protein. 30 9.3
AJ003144-1|CAA05900.1| 183|Homo sapiens metalloproteinase protein. 30 9.3
AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase h... 30 9.3
AF185270-1|AAG17007.1| 562|Homo sapiens leukolysin protein. 30 9.3
AF145442-1|AAF66697.2| 562|Homo sapiens leukolysin protein. 30 9.3
AB042328-1|BAB20584.1| 562|Homo sapiens membrane-type 6 matrix ... 30 9.3
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 217 bits (531), Expect = 2e-56
Identities = 105/214 (49%), Positives = 136/214 (63%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL A GG+DIL
Sbjct: 65 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 124
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 125 SIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 184
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLTK +A E NIRVNC+APG++ T F+ + + E + ++R G
Sbjct: 185 SKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE 244
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 245 PEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 217 bits (531), Expect = 2e-56
Identities = 105/214 (49%), Positives = 136/214 (63%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL A GG+DIL
Sbjct: 65 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 124
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 125 SIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 184
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLTK +A E NIRVNC+APG++ T F+ + + E + ++R G
Sbjct: 185 SKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE 244
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 245 PEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 217 bits (531), Expect = 2e-56
Identities = 105/214 (49%), Positives = 136/214 (63%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL A GG+DIL
Sbjct: 65 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 124
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 125 SIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 184
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLTK +A E NIRVNC+APG++ T F+ + + E + ++R G
Sbjct: 185 SKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE 244
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 245 PEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 217 bits (531), Expect = 2e-56
Identities = 105/214 (49%), Positives = 136/214 (63%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL A GG+DIL
Sbjct: 65 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 124
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 125 SIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 184
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLTK +A E NIRVNC+APG++ T F+ + + E + ++R G
Sbjct: 185 SKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE 244
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 245 PEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 217 bits (531), Expect = 2e-56
Identities = 105/214 (49%), Positives = 136/214 (63%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL A GG+DIL
Sbjct: 47 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 106
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 107 SIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 166
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLTK +A E NIRVNC+APG++ T F+ + + E + ++R G
Sbjct: 167 SKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE 226
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 227 PEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 260
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 217 bits (530), Expect = 3e-56
Identities = 104/214 (48%), Positives = 137/214 (64%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL +A GG+DIL
Sbjct: 47 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFG 106
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
S++D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 107 SLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 166
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLTK +A E NIRVNC+APG++ T F+ + + E + ++R G
Sbjct: 167 SKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE 226
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 227 PEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 260
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 213 bits (521), Expect = 4e-55
Identities = 104/214 (48%), Positives = 135/214 (63%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VC V E R RL A GG+DIL
Sbjct: 65 KQQNVDQAVATLQGEGLSVTGTVCMVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 124
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 125 SIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 184
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLTK +A E NIRVNC+APG++ T F+ + + E + ++R G
Sbjct: 185 SKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE 244
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 245 PEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 180 bits (437), Expect = 6e-45
Identities = 93/208 (44%), Positives = 123/208 (59%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +A+ L+ EG++V G+VCHV E R +L A GGVD L
Sbjct: 69 KQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVG 128
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
S L T EQ+WDKI VNVKS LL + P + R G +++ +SSIAAY P LG Y V
Sbjct: 129 STLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG-AVILVSSIAAYNPVVALGVYNV 187
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +E+ + + L+R G
Sbjct: 188 SKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGE 247
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAG 85
E+ AG V+FL S DASY+ GE + VAG
Sbjct: 248 SEDCAGIVSFLCSPDASYVNGENIAVAG 275
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 180 bits (437), Expect = 6e-45
Identities = 93/208 (44%), Positives = 123/208 (59%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +A+ L+ EG++V G+VCHV E R +L A GGVD L
Sbjct: 60 KQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVG 119
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
S L T EQ+WDKI VNVKS LL + P + R G +++ +SSIAAY P LG Y V
Sbjct: 120 STLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG-AVILVSSIAAYNPVVALGVYNV 178
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +E+ + + L+R G
Sbjct: 179 SKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGE 238
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAG 85
E+ AG V+FL S DASY+ GE + VAG
Sbjct: 239 SEDCAGIVSFLCSPDASYVNGENIAVAG 266
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 180 bits (437), Expect = 6e-45
Identities = 93/208 (44%), Positives = 123/208 (59%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +A+ L+ EG++V G+VCHV E R +L A GGVD L
Sbjct: 69 KQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVG 128
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
S L T EQ+WDKI VNVKS LL + P + R G +++ +SSIAAY P LG Y V
Sbjct: 129 STLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG-AVILVSSIAAYNPVVALGVYNV 187
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +E+ + + L+R G
Sbjct: 188 SKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGE 247
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAG 85
E+ AG V+FL S DASY+ GE + VAG
Sbjct: 248 SEDCAGIVSFLCSPDASYVNGENIAVAG 275
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 176 bits (429), Expect = 6e-44
Identities = 91/208 (43%), Positives = 122/208 (58%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +A+ L+ EG++V G+VCHV E R +L A GGVD L
Sbjct: 69 KQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVG 128
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
S L T EQ+WDKI VNVKS L + P + R G +++ +SS+AAY P LG Y V
Sbjct: 129 STLGTSEQIWDKILSVNVKSPAPLLSQLLPYMENRRG-AVILVSSVAAYNPVVALGVYSV 187
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +E+ + + L+R G
Sbjct: 188 SKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGE 247
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAG 85
E+ AG V+FL S DASY+ GE + VAG
Sbjct: 248 SEDCAGIVSFLCSPDASYVNGENIAVAG 275
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 155 bits (375), Expect(2) = 1e-43
Identities = 73/140 (52%), Positives = 95/140 (67%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 307
D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y VSKT LLGLTK +A
Sbjct: 105 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 164
Query: 306 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASD 127
E NIRVNC+APG++ T F+ + + E + ++R G PE+ AG V+FL S+
Sbjct: 165 ELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 224
Query: 126 DASYITGETVVVAGGAPARL 67
DASYITGETVVV GG P+RL
Sbjct: 225 DASYITGETVVVGGGTPSRL 244
Score = 42.3 bits (95), Expect(2) = 1e-43
Identities = 21/41 (51%), Positives = 28/41 (68%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 586
K+ NV +AV +L+ EG++V G VCHV E R RL VAT+
Sbjct: 65 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERL--VATT 103
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 144 bits (349), Expect = 3e-34
Identities = 69/146 (47%), Positives = 90/146 (61%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL +A GG+DIL
Sbjct: 63 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFG 122
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
S++D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y V
Sbjct: 123 SLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 182
Query: 348 SKTTLLGLTKAIANETVHENIRVNCV 271
SKT LLGL +A E NIRVNC+
Sbjct: 183 SKTALLGLNNTLAIELAPRNIRVNCL 208
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 144 bits (348), Expect = 4e-34
Identities = 73/159 (45%), Positives = 95/159 (59%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +A+ L+ EG++V G+VCHV E R +L A GGVD L
Sbjct: 69 KQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVG 128
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
S L T EQ+WDKI VNVKS LL + P + R G+++ +SSIAAY P LG Y V
Sbjct: 129 STLGTSEQIWDKILSVNVKSPALLLSQLLPYMENR-RGAVILVSSIAAYNPVVALGVYNV 187
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 232
SKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +
Sbjct: 188 SKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVV 226
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 104 bits (250), Expect = 3e-22
Identities = 59/136 (43%), Positives = 79/136 (58%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVS 346
++D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y VS
Sbjct: 2 LMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVS 61
Query: 345 KTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRP 166
KT LLGL +A E NIRVNC+ + +++ ASA G P
Sbjct: 62 KTALLGLNNTLAIELAPRNIRVNCL--HLDLSRLASA-----------------GWLGEP 102
Query: 165 EEIAGAVAFLASDDAS 118
E+ AG V+FL S+DAS
Sbjct: 103 EDCAGIVSFLCSEDAS 118
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 99.5 bits (237), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L E WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 171
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E IR N V PG + T + +K +P+ G
Sbjct: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGD 229
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 99.5 bits (237), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L E WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 171
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E IR N V PG + T + +K +P+ G
Sbjct: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGD 229
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 99.5 bits (237), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L E WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 171
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E IR N V PG + T + +K +P+ G
Sbjct: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGD 229
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 99.5 bits (237), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L E WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 171
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E IR N V PG + T + +K +P+ G
Sbjct: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGD 229
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 99.5 bits (237), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L E WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 171
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E IR N V PG + T + +K +P+ G
Sbjct: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGD 229
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 99.5 bits (237), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L E WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 171
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E IR N V PG + T + +K +P+ G
Sbjct: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGD 229
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 99.5 bits (237), Expect = 1e-20
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L E WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 171
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E IR N V PG + T + +K +P+ G
Sbjct: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGD 229
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 96.7 bits (230), Expect = 7e-20
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 349
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 181
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 180 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESTYVTGNPVIIDGG 242
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 96.7 bits (230), Expect = 7e-20
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 349
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 181
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 180 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 96.7 bits (230), Expect = 7e-20
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 349
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 181
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 180 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 96.3 bits (229), Expect = 9e-20
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 349
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 181
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSLAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 180 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 95.1 bits (226), Expect = 2e-19
Identities = 59/191 (30%), Positives = 94/191 (49%), Gaps = 3/191 (1%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
+ C++ N E L + FG ++ L + + W + + N+ +
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGT 135
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHEN 289
+ + K Y +K GGSIV I I + PL + G ++ + LTK++A E
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 288 IRVNCVAPGIVVTKFASAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASY 115
IR+NCVAPG++ ++ A S ++ E S +P KR G PEE++ V FL S AS+
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253
Query: 114 ITGETVVVAGG 82
ITG++V V GG
Sbjct: 254 ITGQSVDVDGG 264
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 95.1 bits (226), Expect = 2e-19
Identities = 59/191 (30%), Positives = 94/191 (49%), Gaps = 3/191 (1%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
+ C++ N E L + FG ++ L + + W + + N+ +
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGT 135
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHEN 289
+ + K Y +K GGSIV I I + PL + G ++ + LTK++A E
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 288 IRVNCVAPGIVVTKFASAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASY 115
IR+NCVAPG++ ++ A S ++ E S +P KR G PEE++ V FL S AS+
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253
Query: 114 ITGETVVVAGG 82
ITG++V V GG
Sbjct: 254 ITGQSVDVDGG 264
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 95.1 bits (226), Expect = 2e-19
Identities = 59/191 (30%), Positives = 94/191 (49%), Gaps = 3/191 (1%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
+ C++ N E L + FG ++ L + + W + + N+ +
Sbjct: 96 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGT 154
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHEN 289
+ + K Y +K GGSIV I I + PL + G ++ + LTK++A E
Sbjct: 155 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 212
Query: 288 IRVNCVAPGIVVTKFASAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASY 115
IR+NCVAPG++ ++ A S ++ E S +P KR G PEE++ V FL S AS+
Sbjct: 213 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 272
Query: 114 ITGETVVVAGG 82
ITG++V V GG
Sbjct: 273 ITGQSVDVDGG 283
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 95.1 bits (226), Expect = 2e-19
Identities = 59/191 (30%), Positives = 94/191 (49%), Gaps = 3/191 (1%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
+ C++ N E L + FG ++ L + + W + + N+ +
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGT 135
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHEN 289
+ + K Y +K GGSIV I I + PL + G ++ + LTK++A E
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 288 IRVNCVAPGIVVTKFASAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASY 115
IR+NCVAPG++ ++ A S ++ E S +P KR G PEE++ V FL S AS+
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253
Query: 114 ITGETVVVAGG 82
ITG++V V GG
Sbjct: 254 ITGQSVDVDGG 264
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 94.7 bits (225), Expect = 3e-19
Identities = 54/149 (36%), Positives = 75/149 (50%), Gaps = 1/149 (0%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGV 349
+L WDK+ VN+K ++L+ + A LV G GSI+ ISSI Y
Sbjct: 110 LLHMSRDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAA 169
Query: 348 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGR 169
SK ++GLT+ A E I N V PG + T + +K +P+ G
Sbjct: 170 SKAGVIGLTQTAARELGRHGIPCNSVLPGFIATPMTKKVPKKVV--DKITEMIPMGHLGD 227
Query: 168 PEEIAGAVAFLASDDASYITGETVVVAGG 82
PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 228 PEDVADVVAFLASEDSGYITGTSVEVTGG 256
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 94.7 bits (225), Expect = 3e-19
Identities = 60/191 (31%), Positives = 93/191 (48%), Gaps = 3/191 (1%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
+ C++ N E L + FG ++ L + + W + N+ S
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLRTNLTGS 135
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHEN 289
+ + K Y +K GGSIV I I + PL + G ++ + LTK++A E
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 288 IRVNCVAPGIVVTKFASAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASY 115
IR+NCVAPG++ ++ A S ++ E S +P KR G PEE++ V FL S AS+
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253
Query: 114 ITGETVVVAGG 82
ITG++V V GG
Sbjct: 254 ITGQSVDVDGG 264
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 89.8 bits (213), Expect = 8e-18
Identities = 60/186 (32%), Positives = 84/186 (45%)
Frame = -2
Query: 639 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWL 460
C VA + FE G V+ L + E + ++ N+ S L
Sbjct: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSML 113
Query: 459 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 280
K A ++++ GGSIV + SI + Y SK L+G ++A+A E + IRV
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173
Query: 279 NCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGET 100
N VAPG V T + E N+PL RFG E+A AV FL ++ YITG
Sbjct: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHV 226
Query: 99 VVVAGG 82
+VV GG
Sbjct: 227 LVVDGG 232
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 89.8 bits (213), Expect = 8e-18
Identities = 60/186 (32%), Positives = 84/186 (45%)
Frame = -2
Query: 639 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWL 460
C VA + FE G V+ L + E + ++ N+ S L
Sbjct: 55 CDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSML 113
Query: 459 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 280
K A ++++ GGSIV + SI + Y SK L+G ++A+A E + IRV
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173
Query: 279 NCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGET 100
N VAPG V T + E N+PL RFG E+A AV FL ++ YITG
Sbjct: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHV 226
Query: 99 VVVAGG 82
+VV GG
Sbjct: 227 LVVDGG 232
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 81.0 bits (191), Expect = 4e-15
Identities = 51/193 (26%), Positives = 95/193 (49%), Gaps = 4/193 (2%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
++C V + + L +FG +D + +T Q + ++ ++N+ +
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 286
+ L K A P L ++ G+++ ISS+ Y +K + +TKA+A + +
Sbjct: 119 YTLTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177
Query: 285 RVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDAS 118
RVNC++PG + T + A+ + + A + + PL R G+P E+ A FLAS +A+
Sbjct: 178 RVNCISPGNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236
Query: 117 YITGETVVVAGGA 79
+ TG ++V GGA
Sbjct: 237 FCTGIELLVTGGA 249
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 80.6 bits (190), Expect = 5e-15
Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ A L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIAARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 80.2 bits (189), Expect = 7e-15
Identities = 51/193 (26%), Positives = 95/193 (49%), Gaps = 4/193 (2%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
++C V + + L +FG +D + +T Q + ++ ++N+ +
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 286
+ L K A P L ++ G+++ ISS+ Y +K + +TKA+A + +
Sbjct: 119 YTLTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177
Query: 285 RVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDAS 118
RVNC++PG + T + A+ + + A + + PL R G+P E+ A FLAS +A+
Sbjct: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236
Query: 117 YITGETVVVAGGA 79
+ TG ++V GGA
Sbjct: 237 FCTGIELLVTGGA 249
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 80.2 bits (189), Expect = 7e-15
Identities = 51/193 (26%), Positives = 95/193 (49%), Gaps = 4/193 (2%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
++C V + + L +FG +D + +T Q + ++ ++N+ +
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 286
+ L K A P L ++ G+++ ISS+ Y +K + +TKA+A + +
Sbjct: 119 YTLTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177
Query: 285 RVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDAS 118
RVNC++PG + T + A+ + + A + + PL R G+P E+ A FLAS +A+
Sbjct: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236
Query: 117 YITGETVVVAGGA 79
+ TG ++V GGA
Sbjct: 237 FCTGIELLVTGGA 249
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 80.2 bits (189), Expect = 7e-15
Identities = 51/193 (26%), Positives = 95/193 (49%), Gaps = 4/193 (2%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS 466
++C V + + L +FG +D + +T Q + ++ ++N+ +
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 286
+ L K A P L ++ G+++ ISS+ Y +K + +TKA+A + +
Sbjct: 119 YTLTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177
Query: 285 RVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDAS 118
RVNC++PG + T + A+ + + A + + PL R G+P E+ A FLAS +A+
Sbjct: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236
Query: 117 YITGETVVVAGGA 79
+ TG ++V GGA
Sbjct: 237 FCTGIELLVTGGA 249
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 67 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 125
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 126 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 185
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 186 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 239
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 600 EVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 421
E A G VD+L L+ ++ +D+ F+VN+++ +++ L+ RG
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126
Query: 420 -GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 244
G+IV +SS + + Y +K L LTK +A E IRVN V P +V+T
Sbjct: 127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
Query: 243 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
A + A+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 187 GQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 76.6 bits (180), Expect = 8e-14
Identities = 47/120 (39%), Positives = 68/120 (56%), Gaps = 3/120 (2%)
Frame = -2
Query: 432 VKRGGGSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
+K GGSIV I I + PL + G ++ + LTK++A E IR+NCVAPG++
Sbjct: 1 MKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVI 58
Query: 255 VTKFASAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 82
++ A S ++ E S +P KR G PEE++ V FL AS+ITG++V V GG
Sbjct: 59 YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLPPAASFITGQSVDVDGG 118
>DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B2 isoform protein.
Length = 160
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -2
Query: 210 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 113 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 160
Score = 50.4 bits (115), Expect(2) = 1e-12
Identities = 21/38 (55%), Positives = 29/38 (76%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPT 373
D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+
Sbjct: 66 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPS 103
Score = 42.3 bits (95), Expect(2) = 1e-12
Identities = 21/41 (51%), Positives = 28/41 (68%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 586
K+ NV +AV +L+ EG++V G VCHV E R RL VAT+
Sbjct: 26 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERL--VATT 64
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 69.7 bits (163), Expect = 9e-12
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = -2
Query: 639 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWL 460
C ++N E +F S+ GVDI +L W +F+VNV + +
Sbjct: 69 CDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSI 127
Query: 459 LAKEAYPELVKRG--GGSIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--V 298
+EAY + +R G I+ I+S++ ++ P Y +K + LT+ + E
Sbjct: 128 CTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREA 187
Query: 297 HENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDAS 118
+IR C++PG+V T+FA + + + EK+ + + +PE++A AV ++ S A
Sbjct: 188 QTHIRATCISPGVVETQFAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAH 245
Query: 117 YITGE 103
G+
Sbjct: 246 IQIGD 250
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 69.7 bits (163), Expect = 9e-12
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = -2
Query: 639 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWL 460
C ++N E +F S+ GVDI +L W +F+VNV + +
Sbjct: 69 CDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSI 127
Query: 459 LAKEAYPELVKRG--GGSIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--V 298
+EAY + +R G I+ I+S++ ++ P Y +K + LT+ + E
Sbjct: 128 CTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREA 187
Query: 297 HENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDAS 118
+IR C++PG+V T+FA + + + EK+ + + +PE++A AV ++ S A
Sbjct: 188 QTHIRATCISPGVVETQFAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAH 245
Query: 117 YITGE 103
G+
Sbjct: 246 IQIGD 250
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 85 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 144
Query: 312 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 136
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 145 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 204
Query: 135 ASDDASYITGETVVVAGGA 79
AS ASY+TG +V GGA
Sbjct: 205 ASPLASYVTGAVLVADGGA 223
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 312 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 136
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 135 ASDDASYITGETVVVAGGA 79
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 68.5 bits (160), Expect = 2e-11
Identities = 32/74 (43%), Positives = 43/74 (58%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL A GG+DIL
Sbjct: 47 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 106
Query: 528 SILDTDEQVWDKIF 487
SI+D E+VWDK++
Sbjct: 107 SIMDVTEEVWDKLW 120
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -2
Query: 210 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 127 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 174
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 312 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 136
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 135 ASDDASYITGETVVVAGGA 79
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 121 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 180
Query: 312 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 136
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 181 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 240
Query: 135 ASDDASYITGETVVVAGGA 79
AS ASY+TG +V GGA
Sbjct: 241 ASPLASYVTGAVLVADGGA 259
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 312 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 136
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 135 ASDDASYITGETVVVAGGA 79
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 312 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 136
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 135 ASDDASYITGETVVVAGGA 79
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retinol
dehydrogenase A2 isoform protein.
Length = 188
Score = 67.3 bits (157), Expect = 5e-11
Identities = 32/72 (44%), Positives = 41/72 (56%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +AV +L+ EG++V G VCHV E R RL A GG+DIL
Sbjct: 65 KQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFG 124
Query: 528 SILDTDEQVWDK 493
SI+D E+VWDK
Sbjct: 125 SIMDVTEEVWDK 136
>AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase A1 like protein 1 protein.
Length = 57
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -2
Query: 210 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 10 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 57
>AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform-like protein 1
protein.
Length = 91
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -2
Query: 210 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 67
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 44 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 91
Score = 31.1 bits (67), Expect = 4.0
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 597 VATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIF 487
+A GG+DIL S++D E+VWDK++
Sbjct: 1 MAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKLW 37
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/73 (41%), Positives = 40/73 (54%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
K+ NV +A+ L+ EG++V G+VCHV E R +L A GGVD L
Sbjct: 86 KQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVG 145
Query: 528 SILDTDEQVWDKI 490
S L T EQ+WDK+
Sbjct: 146 STLGTSEQIWDKV 158
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 6/168 (3%)
Frame = -2
Query: 588 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG--GG 415
S+ GVDI +L W +F+VNV + + +EAY + +R G
Sbjct: 7 SQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDG 65
Query: 414 SIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--VHENIRVNCVAPGIVVTK 247
I+ I+S++ ++ P Y +K + LT+ + E +IR C++PG+V T+
Sbjct: 66 HIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 125
Query: 246 FASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGE 103
FA + + + EK+ + + +PE++A AV ++ S A G+
Sbjct: 126 FAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGD 171
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 6/168 (3%)
Frame = -2
Query: 588 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG--GG 415
S+ GVDI +L W +F+VNV + + +EAY + +R G
Sbjct: 7 SQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDG 65
Query: 414 SIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--VHENIRVNCVAPGIVVTK 247
I+ I+S++ ++ P Y +K + LT+ + E +IR C++PG+V T+
Sbjct: 66 HIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 125
Query: 246 FASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGE 103
FA + + + EK+ + + +PE++A AV ++ S A G+
Sbjct: 126 FAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGD 171
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 60.5 bits (140), Expect = 6e-09
Identities = 37/126 (29%), Positives = 55/126 (43%)
Frame = -2
Query: 639 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWL 460
C VA + FE G V+ L + E + ++ N+ S L
Sbjct: 55 CDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSML 113
Query: 459 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 280
K A ++++ GGSIV + SI + Y SK L+G ++A+A E + IRV
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173
Query: 279 NCVAPG 262
N VAPG
Sbjct: 174 NVVAPG 179
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 58.4 bits (135), Expect = 2e-08
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = -2
Query: 501 WDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 325
W I D+ + + + E +L+K + G + + I++I A + + +K + +
Sbjct: 161 WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAM 220
Query: 324 TKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL-SNVPLKRFGRPEEIAGA 148
+K++A E +R N + PG + TK A + + EK + +P R G EE+A
Sbjct: 221 SKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANL 280
Query: 147 VAFLASDDASYITGETVVVAGG 82
AFL SD AS+I G + GG
Sbjct: 281 AAFLCSDYASWINGAVIKFDGG 302
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 58.4 bits (135), Expect = 2e-08
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = -2
Query: 501 WDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 325
W I D+ + + + E +L+K + G + + I++I A + + +K + +
Sbjct: 161 WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAM 220
Query: 324 TKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL-SNVPLKRFGRPEEIAGA 148
+K++A E +R N + PG + TK A + + EK + +P R G EE+A
Sbjct: 221 SKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANL 280
Query: 147 VAFLASDDASYITGETVVVAGG 82
AFL SD AS+I G + GG
Sbjct: 281 AAFLCSDYASWINGAVIKFDGG 302
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 58.4 bits (135), Expect = 2e-08
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = -2
Query: 501 WDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 325
W I D+ + + + E +L+K + G + + I++I A + + +K + +
Sbjct: 161 WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAM 220
Query: 324 TKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL-SNVPLKRFGRPEEIAGA 148
+K++A E +R N + PG + TK A + + EK + +P R G EE+A
Sbjct: 221 SKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANL 280
Query: 147 VAFLASDDASYITGETVVVAGG 82
AFL SD AS+I G + GG
Sbjct: 281 AAFLCSDYASWINGAVIKFDGG 302
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 58.4 bits (135), Expect = 2e-08
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = -2
Query: 501 WDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 325
W I D+ + + + E +L+K + G + + I++I A + + +K + +
Sbjct: 161 WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAM 220
Query: 324 TKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL-SNVPLKRFGRPEEIAGA 148
+K++A E +R N + PG + TK A + + EK + +P R G EE+A
Sbjct: 221 SKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANL 280
Query: 147 VAFLASDDASYITGETVVVAGG 82
AFL SD AS+I G + GG
Sbjct: 281 AAFLCSDYASWINGAVIKFDGG 302
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 58.4 bits (135), Expect = 2e-08
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = -2
Query: 501 WDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 325
W I D+ + + + E +L+K + G + + I++I A + + +K + +
Sbjct: 161 WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAM 220
Query: 324 TKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL-SNVPLKRFGRPEEIAGA 148
+K++A E +R N + PG + TK A + + EK + +P R G EE+A
Sbjct: 221 SKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANL 280
Query: 147 VAFLASDDASYITGETVVVAGG 82
AFL SD AS+I G + GG
Sbjct: 281 AAFLCSDYASWINGAVIKFDGG 302
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 55.2 bits (127), Expect = 2e-07
Identities = 38/142 (26%), Positives = 68/142 (47%), Gaps = 2/142 (1%)
Frame = -2
Query: 501 WDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 325
W I D+ + + + E +L+K + G + + I++I A + + +K + +
Sbjct: 161 WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAM 220
Query: 324 TKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL-SNVPLKRFGRPEEIAGA 148
+K++A E +R N + PG + TK A + + EK + +P R G EE+A
Sbjct: 221 SKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANL 280
Query: 147 VAFLASDDASYITGETVVVAGG 82
AFL S AS++ G + GG
Sbjct: 281 AAFLCSGYASWVNGAVIKFDGG 302
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/142 (25%), Positives = 62/142 (43%)
Frame = -2
Query: 690 KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTD 511
K V+ +R G V + + E ++ + A FG +D++ +D
Sbjct: 57 KVVEEIRRRG---GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISD 113
Query: 510 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 331
E WD I V+++ S+ + + A+ + K+ G I+ SS + Y +K LL
Sbjct: 114 ED-WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLL 172
Query: 330 GLTKAIANETVHENIRVNCVAP 265
GL ++A E NI N +AP
Sbjct: 173 GLANSLAIEGRKSNIHCNTIAP 194
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 52.0 bits (119), Expect = 2e-06
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---V 475
+ C VA+ + R F FG +DIL +E+ W+K +N V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSV 111
Query: 474 KSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANET 301
S L + + GG I+ +SS+A P Y SK ++G T+ A+A
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171
Query: 300 VHENIRVNCVAPGIVVTKFASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAF 139
++ +R+N + PG V T +I E + K +K +G P IA +
Sbjct: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLIT 231
Query: 138 LASDDA 121
L DDA
Sbjct: 232 LIEDDA 237
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 52.0 bits (119), Expect = 2e-06
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---V 475
+ C VA+ + R F FG +DIL +E+ W+K +N V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSV 111
Query: 474 KSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANET 301
S L + + GG I+ +SS+A P Y SK ++G T+ A+A
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171
Query: 300 VHENIRVNCVAPGIVVTKFASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAF 139
++ +R+N + PG V T +I E + K +K +G P IA +
Sbjct: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLIT 231
Query: 138 LASDDA 121
L DDA
Sbjct: 232 LIEDDA 237
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 52.0 bits (119), Expect = 2e-06
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---V 475
+ C VA+ + R F FG +DIL +E+ W+K +N V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSV 111
Query: 474 KSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANET 301
S L + + GG I+ +SS+A P Y SK ++G T+ A+A
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171
Query: 300 VHENIRVNCVAPGIVVTKFASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAF 139
++ +R+N + PG V T +I E + K +K +G P IA +
Sbjct: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLIT 231
Query: 138 LASDDA 121
L DDA
Sbjct: 232 LIEDDA 237
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 52.0 bits (119), Expect = 2e-06
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---V 475
+ C VA+ + R F FG +DIL +E+ W+K +N V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSV 111
Query: 474 KSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANET 301
S L + + GG I+ +SS+A P Y SK ++G T+ A+A
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171
Query: 300 VHENIRVNCVAPGIVVTKFASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAF 139
++ +R+N + PG V T +I E + K +K +G P IA +
Sbjct: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLIT 231
Query: 138 LASDDA 121
L DDA
Sbjct: 232 LIEDDA 237
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/142 (25%), Positives = 62/142 (43%)
Frame = -2
Query: 690 KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTD 511
K V+ +R G V + + E ++ + A FG +D++ +D
Sbjct: 57 KVVEEIRRRG---GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISD 113
Query: 510 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 331
E WD I V+++ S+ + + A+ + K+ G I+ SS + Y +K LL
Sbjct: 114 ED-WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLL 172
Query: 330 GLTKAIANETVHENIRVNCVAP 265
GL ++A E NI N +AP
Sbjct: 173 GLANSLAIEGRKSNIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/142 (25%), Positives = 62/142 (43%)
Frame = -2
Query: 690 KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTD 511
K V+ +R G V + + E ++ + A FG +D++ +D
Sbjct: 57 KVVEEIRRRG---GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISD 113
Query: 510 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 331
E WD I V+++ S+ + + A+ + K+ G I+ SS + Y +K LL
Sbjct: 114 ED-WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLL 172
Query: 330 GLTKAIANETVHENIRVNCVAP 265
GL ++A E NI N +AP
Sbjct: 173 GLANSLAIEGRKSNIHCNTIAP 194
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 51.2 bits (117), Expect = 4e-06
Identities = 29/93 (31%), Positives = 51/93 (54%)
Frame = -2
Query: 516 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 337
+++++WD I +VN+ ++ L+ P +V+R G+IV ISS + +PT L A+ SK
Sbjct: 166 SEDKLWD-IINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAY 224
Query: 336 LLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 238
L ++A+ E + I V + P V T +
Sbjct: 225 LDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 51.2 bits (117), Expect = 4e-06
Identities = 29/93 (31%), Positives = 51/93 (54%)
Frame = -2
Query: 516 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 337
+++++WD I +VN+ ++ L+ P +V+R G+IV ISS + +PT L A+ SK
Sbjct: 145 SEDKLWD-IINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAY 203
Query: 336 LLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 238
L ++A+ E + I V + P V T +
Sbjct: 204 LDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 236
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 51.2 bits (117), Expect = 4e-06
Identities = 29/93 (31%), Positives = 51/93 (54%)
Frame = -2
Query: 516 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 337
+++++WD I +VN+ ++ L+ P +V+R G+IV ISS + +PT L A+ SK
Sbjct: 166 SEDKLWD-IINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAY 224
Query: 336 LLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 238
L ++A+ E + I V + P V T +
Sbjct: 225 LDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 51.2 bits (117), Expect = 4e-06
Identities = 29/93 (31%), Positives = 51/93 (54%)
Frame = -2
Query: 516 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 337
+++++WD I +VN+ ++ L+ P +V+R G+IV ISS + +PT L A+ SK
Sbjct: 145 SEDKLWD-IINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAY 203
Query: 336 LLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 238
L ++A+ E + I V + P V T +
Sbjct: 204 LDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 236
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 50.0 bits (114), Expect = 8e-06
Identities = 28/93 (30%), Positives = 51/93 (54%)
Frame = -2
Query: 516 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 337
+++++WD I +VN+ ++ L+ P +V+R G+IV ISS + +PT L A+ S+
Sbjct: 166 SEDKLWD-IINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASRAY 224
Query: 336 LLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 238
L ++A+ E + I V + P V T +
Sbjct: 225 LDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 50.0 bits (114), Expect = 8e-06
Identities = 28/93 (30%), Positives = 51/93 (54%)
Frame = -2
Query: 516 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 337
+++++WD I +VN+ ++ L+ P +V+R G+IV ISS + +PT L A+ S+
Sbjct: 166 SEDKLWD-IINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASRAY 224
Query: 336 LLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 238
L ++A+ E + I V + P V T +
Sbjct: 225 LDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens
cDNA FLJ13960 fis, clone Y79AA1001233, weakly similar to
ESTRADIOL 17 BETA-DEHYDROGENASE 1 (EC 1.1.1.62). ).
Length = 219
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/95 (32%), Positives = 46/95 (48%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+FD N + L K P + +R G IV ISS+ Q Y SK L G +++
Sbjct: 18 VFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESL 77
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNSEAGAE 208
A + + NI ++ V PG VVT+F + + AE
Sbjct: 78 AIQLLQFNIFISLVEPGPVVTEFEGKLLAQVSMAE 112
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/95 (32%), Positives = 46/95 (48%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+FD N + L K P + +R G IV ISS+ Q Y SK L G +++
Sbjct: 110 VFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESL 169
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNSEAGAE 208
A + + NI ++ V PG VVT+F + + AE
Sbjct: 170 AIQLLQFNIFISLVEPGPVVTEFEGKLLAQVSMAE 204
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/93 (30%), Positives = 50/93 (53%)
Frame = -2
Query: 516 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 337
+++++WD I +VN+ ++ L+ P +V+R G+IV ISS + +PT L A+ SK
Sbjct: 166 SEDKLWD-IINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAY 224
Query: 336 LLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 238
L ++A+ E + I V + P V +
Sbjct: 225 LDHFSRALQYEYASKGIFVQSLIPFYVAASMTA 257
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 48.4 bits (110), Expect = 2e-05
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 231
Query: 162 EIAGAVAFLASDDASYITGETVVVAG 85
E A V + + ++ GE + + G
Sbjct: 232 EYAHLVQAIIEN--PFLNGEVIRLDG 255
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 47.6 bits (108), Expect = 4e-05
Identities = 38/156 (24%), Positives = 58/156 (37%), Gaps = 3/156 (1%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
KE N + + V C + E R+ + + G V IL
Sbjct: 74 KEGNEETCKMAREAGATRVRAYTCDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKK 133
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
LD +++ +K FDVN K+ K P ++ G +V ISS A L Y
Sbjct: 134 -FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCA 192
Query: 348 SKTTLLGLTKAIANETV---HENIRVNCVAPGIVVT 250
SK G +++ ET + I+ V P + T
Sbjct: 193 SKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKT 228
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
Frame = -2
Query: 582 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 403
FG VDIL I+DT V ++ + N L K P ++KR G IV
Sbjct: 133 FGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVA 191
Query: 402 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAIT 229
ISSI AY SK + E I V ++PG + T + +AIT
Sbjct: 192 ISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAIT 250
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/156 (24%), Positives = 58/156 (37%), Gaps = 3/156 (1%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
KE N + + V C + E R+ + + G V IL
Sbjct: 74 KEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
LD +++ +K FDVN K+ K P ++ G +V ISS A L Y
Sbjct: 134 -FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCA 192
Query: 348 SKTTLLGLTKAIANETV---HENIRVNCVAPGIVVT 250
SK G +++ ET + I+ V P + T
Sbjct: 193 SKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKT 228
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/156 (24%), Positives = 58/156 (37%), Gaps = 3/156 (1%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
KE N + + V C + E R+ + + G V IL
Sbjct: 74 KEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
LD +++ +K FDVN K+ K P ++ G +V ISS A L Y
Sbjct: 134 -FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCA 192
Query: 348 SKTTLLGLTKAIANETV---HENIRVNCVAPGIVVT 250
SK G +++ ET + I+ V P + T
Sbjct: 193 SKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKT 228
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
Frame = -2
Query: 582 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 403
FG VDIL I+DT V ++ + N L K P ++KR G IV
Sbjct: 133 FGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVA 191
Query: 402 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAIT 229
ISSI AY SK + E I V ++PG + T + +AIT
Sbjct: 192 ISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAIT 250
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
Frame = -2
Query: 582 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 403
FG VDIL I+DT V ++ + N L K P ++KR G IV
Sbjct: 133 FGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVA 191
Query: 402 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAIT 229
ISSI AY SK + E I V ++PG + T + +AIT
Sbjct: 192 ISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAIT 250
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
Frame = -2
Query: 582 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 403
FG VDIL I+DT V ++ + N L K P ++KR G IV
Sbjct: 118 FGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVA 176
Query: 402 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAIT 229
ISSI AY SK + E I V ++PG + T + +AIT
Sbjct: 177 ISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAIT 235
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
Frame = -2
Query: 582 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 403
FG VDIL I+DT V ++ + N L K P ++KR G IV
Sbjct: 138 FGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVA 196
Query: 402 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAIT 229
ISSI AY SK + E I V ++PG + T + +AIT
Sbjct: 197 ISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAIT 255
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 46.0 bits (104), Expect = 1e-04
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 7/126 (5%)
Frame = -2
Query: 501 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 340
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 64 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 123
Query: 339 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 163
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 124 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 181
Query: 162 EIAGAV 145
E A V
Sbjct: 182 EYAHLV 187
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 46.0 bits (104), Expect = 1e-04
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 3/151 (1%)
Frame = -2
Query: 708 KESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
KE N + + V C + E R+ + + G V IL
Sbjct: 74 KEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
Query: 528 SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGV 349
LD +++ +K FDVN K+ K P ++ G +V ISS A L Y
Sbjct: 134 -FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCA 192
Query: 348 SKTTLLGLTKAIANETV---HENIRVNCVAP 265
SK G +++ ET + I+ V P
Sbjct: 193 SKFAAFGFAESVFVETFVQKQKGIKTTIVCP 223
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 307
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 306 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 187
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 307
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 306 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 187
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 307
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 306 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 187
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 307
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 306 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 187
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 307
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 306 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 187
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -2
Query: 486 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 307
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 306 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 187
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 40.7 bits (91), Expect = 0.005
Identities = 16/47 (34%), Positives = 33/47 (70%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA 385
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 40.7 bits (91), Expect = 0.005
Identities = 16/47 (34%), Positives = 33/47 (70%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA 385
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 40.7 bits (91), Expect = 0.005
Identities = 16/47 (34%), Positives = 33/47 (70%)
Frame = -2
Query: 525 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA 385
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/90 (27%), Positives = 44/90 (48%)
Frame = -2
Query: 510 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 331
+ V K+ ++N+ S + + P +V+R G+I+ ISS + P L Y +KT +
Sbjct: 151 DNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVD 210
Query: 330 GLTKAIANETVHENIRVNCVAPGIVVTKFA 241
++ + E + + V V P V TK A
Sbjct: 211 FFSQCLHEEYRSKGVFVQSVLPYFVATKLA 240
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/90 (27%), Positives = 44/90 (48%)
Frame = -2
Query: 510 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 331
+ V K+ ++N+ S + + P +V+R G+I+ ISS + P L Y +KT +
Sbjct: 151 DNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVD 210
Query: 330 GLTKAIANETVHENIRVNCVAPGIVVTKFA 241
++ + E + + V V P V TK A
Sbjct: 211 FFSQCLHEEYRSKGVFVQSVLPYFVATKLA 240
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/90 (27%), Positives = 44/90 (48%)
Frame = -2
Query: 510 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 331
+ V K+ ++N+ S + + P +V+R G+I+ ISS + P L Y +KT +
Sbjct: 16 DNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVD 75
Query: 330 GLTKAIANETVHENIRVNCVAPGIVVTKFA 241
++ + E + + V V P V TK A
Sbjct: 76 FFSQCLHEEYRSKGVFVQSVLPYFVATKLA 105
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 39.1 bits (87), Expect = 0.015
Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 2/143 (1%)
Frame = -2
Query: 687 AVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDE 508
A + + + G + V + + E A KFGG+DIL + LDT
Sbjct: 57 AAEEIEAVGGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNT-LDTPT 115
Query: 507 QVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPT--EPLGAYGVSKTTL 334
+ D + +VN + ++L +K P L K I+ IS P + AY ++K +
Sbjct: 116 KRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGM 175
Query: 333 LGLTKAIANETVHENIRVNCVAP 265
+A E E I VN + P
Sbjct: 176 SMYVLGMAEEFKGE-IAVNALWP 197
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 39.1 bits (87), Expect = 0.015
Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 2/143 (1%)
Frame = -2
Query: 687 AVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDE 508
A + + + G + V + + E A KFGG+DIL + LDT
Sbjct: 57 AAEEIEAVGGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNT-LDTPT 115
Query: 507 QVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPT--EPLGAYGVSKTTL 334
+ D + +VN + ++L +K P L K I+ IS P + AY ++K +
Sbjct: 116 KRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGM 175
Query: 333 LGLTKAIANETVHENIRVNCVAP 265
+A E E I VN + P
Sbjct: 176 SMYVLGMAEEFKGE-IAVNALWP 197
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 39.1 bits (87), Expect = 0.015
Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 2/143 (1%)
Frame = -2
Query: 687 AVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDE 508
A + + + G + V + + E A KFGG+DIL + LDT
Sbjct: 57 AAEEIEAVGGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNT-LDTPT 115
Query: 507 QVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPT--EPLGAYGVSKTTL 334
+ D + +VN + ++L +K P L K I+ IS P + AY ++K +
Sbjct: 116 KRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGM 175
Query: 333 LGLTKAIANETVHENIRVNCVAP 265
+A E E I VN + P
Sbjct: 176 SMYVLGMAEEFKGE-IAVNALWP 197
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 38.7 bits (86), Expect = 0.020
Identities = 45/176 (25%), Positives = 69/176 (39%), Gaps = 7/176 (3%)
Frame = -2
Query: 681 QSLRSEGITVEGVVCHVANHEHRRRLFE-VATSKFGGVDILXXXXXXXXXXX------SI 523
Q +S G VVC + R LFE V + G +D+L +
Sbjct: 49 QEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAF 108
Query: 522 LDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSK 343
+T +WD I +V ++ + + +V G G IV ISS + Q + YGV K
Sbjct: 109 WETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGK 167
Query: 342 TTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRF 175
L A+E + + PGIV T+ + E+ L + LK+F
Sbjct: 168 AACDKLAADCAHELRRHGVSCVSLWPGIVQTE----LLKEHMAKEEVLQDPVLKQF 219
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 38.7 bits (86), Expect = 0.020
Identities = 45/176 (25%), Positives = 69/176 (39%), Gaps = 7/176 (3%)
Frame = -2
Query: 681 QSLRSEGITVEGVVCHVANHEHRRRLFE-VATSKFGGVDILXXXXXXXXXXX------SI 523
Q +S G VVC + R LFE V + G +D+L +
Sbjct: 49 QEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAF 108
Query: 522 LDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSK 343
+T +WD I +V ++ + + +V G G IV ISS + Q + YGV K
Sbjct: 109 WETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-LYGVGK 167
Query: 342 TTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRF 175
L A+E + + PGIV T+ + E+ L + LK+F
Sbjct: 168 AACDKLAADCAHELRRHGVSCVSLWPGIVQTE----LLKEHMAKEEVLQDPVLKQF 219
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 38.7 bits (86), Expect = 0.020
Identities = 45/176 (25%), Positives = 69/176 (39%), Gaps = 7/176 (3%)
Frame = -2
Query: 681 QSLRSEGITVEGVVCHVANHEHRRRLFE-VATSKFGGVDILXXXXXXXXXXX------SI 523
Q +S G VVC + R LFE V + G +D+L +
Sbjct: 49 QEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAF 108
Query: 522 LDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSK 343
+T +WD I +V ++ + + +V G G IV ISS + Q + YGV K
Sbjct: 109 WETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGK 167
Query: 342 TTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRF 175
L A+E + + PGIV T+ + E+ L + LK+F
Sbjct: 168 AACDKLAADCAHELRRHGVSCVSLWPGIVQTE----LLKEHMAKEEVLQDPVLKQF 219
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 38.7 bits (86), Expect = 0.020
Identities = 45/176 (25%), Positives = 69/176 (39%), Gaps = 7/176 (3%)
Frame = -2
Query: 681 QSLRSEGITVEGVVCHVANHEHRRRLFE-VATSKFGGVDILXXXXXXXXXXX------SI 523
Q +S G VVC + R LFE V + G +D+L +
Sbjct: 49 QEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAF 108
Query: 522 LDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSK 343
+T +WD I +V ++ + + +V G G IV ISS + Q + YGV K
Sbjct: 109 WETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGK 167
Query: 342 TTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRF 175
L A+E + + PGIV T+ + E+ L + LK+F
Sbjct: 168 AACDKLAADCAHELRRHGVSCVSLWPGIVQTE----LLKEHMAKEEVLQDPVLKQF 219
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.081
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 255 VTKFASAITNSEAGAEKSLSNVP 187
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.081
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 255 VTKFASAITNSEAGAEKSLSNVP 187
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.081
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 255 VTKFASAITNSEAGAEKSLSNVP 187
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.081
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 255 VTKFASAITNSEAGAEKSLSNVP 187
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.081
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 255 VTKFASAITNSEAGAEKSLSNVP 187
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.081
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 255 VTKFASAITNSEAGAEKSLSNVP 187
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 35.1 bits (77), Expect = 0.25
Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 3/115 (2%)
Frame = -2
Query: 645 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---V 475
+ C VA+ + R F FG +DIL +++ W+K +N V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV---------NNKKNWEKTLQINLVSV 111
Query: 474 KSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIA 310
S L + + GG I+ +SS+A P Y SK ++G T++ A
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 35.1 bits (77), Expect = 0.25
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNS 223
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.25
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNS 223
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.25
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNS 223
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 35.1 bits (77), Expect = 0.25
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNS 223
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 35.1 bits (77), Expect = 0.25
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNS 223
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.25
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNS 223
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.25
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAITNS 223
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 33.5 bits (73), Expect = 0.76
Identities = 24/79 (30%), Positives = 40/79 (50%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G ++ I+S+ G Y VSK L + ++ + H IRV+ V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGF- 207
Query: 255 VTKFASAITNSEAGAEKSL 199
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 33.5 bits (73), Expect = 0.76
Identities = 24/79 (30%), Positives = 40/79 (50%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G ++ I+S+ G Y VSK L + ++ + H IRV+ V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGF- 207
Query: 255 VTKFASAITNSEAGAEKSL 199
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 33.5 bits (73), Expect = 0.76
Identities = 24/79 (30%), Positives = 40/79 (50%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G ++ I+S+ G Y VSK L + ++ + H IRV+ V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGF- 207
Query: 255 VTKFASAITNSEAGAEKSL 199
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 255 VTKFASAI 232
T A +
Sbjct: 210 KTNLADPV 217
>M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase protein.
Length = 214
Score = 32.3 bits (70), Expect = 1.7
Identities = 20/87 (22%), Positives = 39/87 (44%)
Frame = -2
Query: 492 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 313
+ DVNV + + ++ P++ + G G ++ S+ Y SK L GL +++
Sbjct: 108 VLDVNVVGTVRVLQDFLPDMKRPGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESL 167
Query: 312 ANETVHENIRVNCVAPGIVVTKFASAI 232
A + + V+ + G V T F +
Sbjct: 168 AVLLLPFGVHVSLIECGPVDTAFMQKV 194
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LV+R G IV +SSI + +G Y VSK + + + E H ++++ V PG
Sbjct: 151 LVRRARGRIVNVSSILG-RVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGY- 208
Query: 255 VTKFASAITNSEAGAEK 205
F + +TN E+
Sbjct: 209 ---FRTGMTNMTQSLER 222
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 32.3 bits (70), Expect = 1.7
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 2/144 (1%)
Frame = -2
Query: 705 ESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
E+ + K V + R G V + +A+ E + + A K GG+D L
Sbjct: 63 EALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAG 122
Query: 528 SILDTDEQV-WDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYG 352
+ + + W + VN S L A P L GS+V +SS+ PT Y
Sbjct: 123 TRARSPQATRW--LMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYS 179
Query: 351 VSKTTLLGLTKAIANETVHENIRV 280
+K L G ++ E +++ V
Sbjct: 180 AAKFALDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 32.3 bits (70), Expect = 1.7
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 2/144 (1%)
Frame = -2
Query: 705 ESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXX 529
E+ + K V + R G V + +A+ E + + A K GG+D L
Sbjct: 63 EALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAG 122
Query: 528 SILDTDEQV-WDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYG 352
+ + + W + VN S L A P L GS+V +SS+ PT Y
Sbjct: 123 TRARSPQATRW--LMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYS 179
Query: 351 VSKTTLLGLTKAIANETVHENIRV 280
+K L G ++ E +++ V
Sbjct: 180 AAKFALDGFFGSLRRELDVQDVNV 203
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LV+R G IV +SSI + +G Y VSK + + + E H ++++ V PG
Sbjct: 151 LVRRARGRIVNVSSILG-RVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGY- 208
Query: 255 VTKFASAITNSEAGAEK 205
F + +TN E+
Sbjct: 209 ---FRTGMTNMTQSLER 222
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LV+R G IV +SSI + +G Y VSK + + + E H ++++ V PG
Sbjct: 151 LVRRARGRIVNVSSILG-RVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGY- 208
Query: 255 VTKFASAITNSEAGAEK 205
F + +TN E+
Sbjct: 209 ---FRTGMTNMTQSLER 222
>Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein.
Length = 3570
Score = 31.9 bits (69), Expect = 2.3
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Frame = +2
Query: 482 TSNILSQTCSSVSKIEATAGLTAAFDT-RISTPPNLLVATSNNRLLCS*LAT*QTTP--S 652
T+ IL++ ++ + E+T T R + PP +L T+ + S AT ++P +
Sbjct: 1107 TTWILTELTTTATTTESTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTA 1166
Query: 653 TVMPSLRRLCTAFPTLLS 706
T +P+LR T PT S
Sbjct: 1167 TALPALRSTATT-PTATS 1183
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 31.1 bits (67), Expect = 4.0
Identities = 23/79 (29%), Positives = 39/79 (49%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
L+++ G ++ I+S+ G Y VSK L + ++ + H IR + V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRESIVEPGF- 207
Query: 255 VTKFASAITNSEAGAEKSL 199
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein.
Length = 1354
Score = 30.7 bits (66), Expect = 5.3
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +1
Query: 142 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 321
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 162 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 221
>L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase
protein.
Length = 1354
Score = 30.7 bits (66), Expect = 5.3
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +1
Query: 142 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 321
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 162 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 221
>BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) protein.
Length = 1356
Score = 30.7 bits (66), Expect = 5.3
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +1
Query: 142 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 321
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 164 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 223
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 30.7 bits (66), Expect = 5.3
Identities = 29/119 (24%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Frame = -2
Query: 633 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQV-WDKIFDVNVKSSWLL 457
+A+ E + + A K GG+D L + + + W + VN S L
Sbjct: 1 MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRW--LMQVNFVSYVQL 58
Query: 456 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 280
A P L GS+V +SS+ PT Y +K L G ++ E +++ V
Sbjct: 59 TSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
>AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial
growth factor receptor 2 protein.
Length = 1356
Score = 30.7 bits (66), Expect = 5.3
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +1
Query: 142 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 321
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 164 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 223
>AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein.
Length = 1356
Score = 30.7 bits (66), Expect = 5.3
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +1
Query: 142 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 321
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 164 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 223
>AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) variant
protein.
Length = 1451
Score = 30.7 bits (66), Expect = 5.3
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +1
Query: 142 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 321
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 259 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 318
>AJ272137-1|CAC03490.1| 562|Homo sapiens membrane type matrix
metalloproteinase number 6 protein.
Length = 562
Score = 29.9 bits (64), Expect = 9.3
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 115 VAGVIRSQKRYGTSNFFWSPESFQWDIR 198
VAG++R ++RY S W + W +R
Sbjct: 98 VAGLVRRRRRYALSGSVWKKRTLTWRVR 125
>AJ239053-1|CAB94713.1| 562|Homo sapiens membrane-type matrix
metalloproteinase 6 protein.
Length = 562
Score = 29.9 bits (64), Expect = 9.3
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 115 VAGVIRSQKRYGTSNFFWSPESFQWDIR 198
VAG++R ++RY S W + W +R
Sbjct: 98 VAGLVRRRRRYALSGSVWKKRTLTWRVR 125
>AJ003147-1|CAA05902.1| 183|Homo sapiens metalloproteinase protein.
Length = 183
Score = 29.9 bits (64), Expect = 9.3
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 115 VAGVIRSQKRYGTSNFFWSPESFQWDIR 198
VAG++R ++RY S W + W +R
Sbjct: 22 VAGLVRRRRRYALSGSVWKKRTLTWRVR 49
>AJ003144-1|CAA05900.1| 183|Homo sapiens metalloproteinase protein.
Length = 183
Score = 29.9 bits (64), Expect = 9.3
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 115 VAGVIRSQKRYGTSNFFWSPESFQWDIR 198
VAG++R ++RY S W + W +R
Sbjct: 22 VAGLVRRRRRYALSGSVWKKRTLTWRVR 49
>AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase
homolog isoform-2 protein.
Length = 172
Score = 29.9 bits (64), Expect = 9.3
Identities = 17/68 (25%), Positives = 30/68 (44%)
Frame = -2
Query: 435 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 256
LVK+ G ++ SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 4 LVKKAQGRVINGSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDLKAFGVHVSCIEPGLF 62
Query: 255 VTKFASAI 232
T A +
Sbjct: 63 KTNLADPV 70
>AF185270-1|AAG17007.1| 562|Homo sapiens leukolysin protein.
Length = 562
Score = 29.9 bits (64), Expect = 9.3
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 115 VAGVIRSQKRYGTSNFFWSPESFQWDIR 198
VAG++R ++RY S W + W +R
Sbjct: 98 VAGLVRRRRRYALSGSVWKKRTLTWRVR 125
>AF145442-1|AAF66697.2| 562|Homo sapiens leukolysin protein.
Length = 562
Score = 29.9 bits (64), Expect = 9.3
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 115 VAGVIRSQKRYGTSNFFWSPESFQWDIR 198
VAG++R ++RY S W + W +R
Sbjct: 98 VAGLVRRRRRYALSGSVWKKRTLTWRVR 125
>AB042328-1|BAB20584.1| 562|Homo sapiens membrane-type 6 matrix
metalloproteinase protein.
Length = 562
Score = 29.9 bits (64), Expect = 9.3
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 115 VAGVIRSQKRYGTSNFFWSPESFQWDIR 198
VAG++R ++RY S W + W +R
Sbjct: 98 VAGLVRRRRRYALSGSVWKKRTLTWRVR 125
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,210,344
Number of Sequences: 237096
Number of extensions: 2508884
Number of successful extensions: 7586
Number of sequences better than 10.0: 173
Number of HSP's better than 10.0 without gapping: 7029
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7510
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8231208258
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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