BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fmgV10i23f (642 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q567K5 Cluster: Zgc:111977; n=14; Coelomata|Rep: Zgc:11... 232 5e-60 UniRef50_Q7Z4W1 Cluster: L-xylulose reductase; n=37; Coelomata|R... 211 9e-54 UniRef50_A7S0F0 Cluster: Predicted protein; n=1; Nematostella ve... 173 2e-42 UniRef50_Q201Y9 Cluster: Putative diacetyl/L-xylulose reductase;... 165 6e-40 UniRef50_Q8SYA6 Cluster: RH08058p; n=5; Diptera|Rep: RH08058p - ... 158 9e-38 UniRef50_Q21929 Cluster: Probable L-xylulose reductase; n=3; Bil... 150 2e-35 UniRef50_Q7CUM7 Cluster: AGR_L_1073p; n=6; Alphaproteobacteria|R... 150 3e-35 UniRef50_UPI0000E46E8D Cluster: PREDICTED: similar to dicarbonyl... 149 7e-35 UniRef50_Q92MT5 Cluster: PUTATIVE OXIDOREDUCTASE PROTEIN; n=2; R... 140 3e-32 UniRef50_Q62K95 Cluster: Oxidoreductase, short chain dehydrogena... 140 3e-32 UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomyceta... 122 1e-26 UniRef50_UPI0001555DAD Cluster: PREDICTED: similar to dicarbonyl... 116 5e-25 UniRef50_A0XC03 Cluster: Short-chain dehydrogenase/reductase SDR... 112 6e-24 UniRef50_A0VS96 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23 UniRef50_A3Z051 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23 UniRef50_Q62AB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 109 6e-23 UniRef50_Q28TD9 Cluster: Short-chain dehydrogenase/reductase SDR... 109 6e-23 UniRef50_A6W805 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22 UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP000... 105 9e-22 UniRef50_A7D2W7 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21 UniRef50_Q5KZI9 Cluster: Dehydrogenase; n=5; Bacilli|Rep: Dehydr... 104 2e-21 UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_UPI00005BF380 Cluster: PREDICTED: similar to dicarbonyl... 101 2e-20 UniRef50_Q7WPV2 Cluster: Short chain dehydrogenase; n=2; Bordete... 101 2e-20 UniRef50_Q0RYT4 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 100 6e-20 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 100 6e-20 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 99 8e-20 UniRef50_A1UGS1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 8e-20 UniRef50_A6SY22 Cluster: Oxidoreductase, short chain dehydrogena... 98 1e-19 UniRef50_A1AZ92 Cluster: Short-chain dehydrogenase/reductase SDR... 98 1e-19 UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_A0VRR7 Cluster: Short-chain dehydrogenase/reductase SDR... 96 6e-19 UniRef50_A0QZ64 Cluster: Acetoacetyl-CoA reductase; n=1; Mycobac... 96 6e-19 UniRef50_A0T544 Cluster: Short-chain dehydrogenase/reductase SDR... 96 7e-19 UniRef50_Q1VP55 Cluster: Short chain dehydrogenase; n=4; Bacteri... 95 1e-18 UniRef50_A2W1T9 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_P33368 Cluster: Uncharacterized oxidoreductase yohF; n=... 95 1e-18 UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chai... 95 1e-18 UniRef50_Q3BBM8 Cluster: Xylitol dehydrogenase; n=1; Pantoea ana... 95 1e-18 UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain dehy... 95 2e-18 UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 95 2e-18 UniRef50_A1R350 Cluster: Oxidoreductase, short chain dehydrogena... 94 2e-18 UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specifici... 94 3e-18 UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_Q8RL53 Cluster: MupS; n=1; Pseudomonas fluorescens|Rep:... 94 3e-18 UniRef50_Q2AZB5 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_Q08Z99 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 94 3e-18 UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 p... 93 4e-18 UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola... 93 4e-18 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 93 5e-18 UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 93 7e-18 UniRef50_Q11C87 Cluster: Short-chain dehydrogenase/reductase SDR... 92 9e-18 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 92 9e-18 UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR... 92 9e-18 UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR... 92 9e-18 UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=... 92 9e-18 UniRef50_Q0FYP0 Cluster: Putative oxidoreductase protein; n=1; F... 92 1e-17 UniRef50_A1UP20 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; ... 92 1e-17 UniRef50_Q1YNT8 Cluster: Oxidoreductase, short chain dehydrogena... 91 2e-17 UniRef50_Q1IKU0 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A4SZ40 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_Q26GY6 Cluster: Short-chain dehydrogenases/reductases f... 91 2e-17 UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=... 91 2e-17 UniRef50_Q8YJQ0 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 91 3e-17 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 91 3e-17 UniRef50_A0VRG5 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_A1B7W8 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_Q97RW1 Cluster: Oxidoreductase, short chain dehydrogena... 90 5e-17 UniRef50_Q89CB1 Cluster: Bll7886 protein; n=8; Bradyrhizobiaceae... 90 5e-17 UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;... 90 5e-17 UniRef50_Q15RB1 Cluster: Short-chain dehydrogenase/reductase SDR... 90 5e-17 UniRef50_Q12JI9 Cluster: Short-chain dehydrogenase/reductase SDR... 90 5e-17 UniRef50_Q11EZ4 Cluster: Short-chain dehydrogenase/reductase SDR... 90 5e-17 UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteri... 90 5e-17 UniRef50_A5V7U7 Cluster: Short-chain dehydrogenase/reductase SDR... 90 5e-17 UniRef50_Q393N0 Cluster: Short-chain dehydrogenase/reductase SDR... 89 6e-17 UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR... 89 6e-17 UniRef50_Q89NC8 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 89 8e-17 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 89 8e-17 UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep... 89 8e-17 UniRef50_Q6W1M4 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 89 8e-17 UniRef50_A3PZB7 Cluster: Short-chain dehydrogenase/reductase SDR... 89 8e-17 UniRef50_Q46MD0 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A3J7V6 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_P0A2D1 Cluster: Oxidoreductase ucpA; n=21; Bacteria|Rep... 89 1e-16 UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Re... 88 1e-16 UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketor... 88 1e-16 UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 88 1e-16 UniRef50_Q5FKH2 Cluster: Oxidoreductase, short chaindehydrogenas... 88 1e-16 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 88 1e-16 UniRef50_Q392C0 Cluster: Short-chain dehydrogenase/reductase SDR... 88 1e-16 UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR... 88 1e-16 UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain dehydrogena... 88 1e-16 UniRef50_A3YG01 Cluster: Short-chain dehydrogenase/reductase SDR... 88 1e-16 UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR... 88 1e-16 UniRef50_Q825Y8 Cluster: Putative dehydrogenase; n=1; Streptomyc... 88 2e-16 UniRef50_P71079 Cluster: Unidentfied dehydrogenase; n=23; Bacill... 88 2e-16 UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A6PU89 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A0TC55 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_Q6ADW8 Cluster: Oxidoreductase; n=3; Actinomycetales|Re... 87 3e-16 UniRef50_Q5YUD9 Cluster: Putative short chain dehydrogenase; n=1... 87 3e-16 UniRef50_Q6W1M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 87 3e-16 UniRef50_Q1VSS0 Cluster: Gluconate 5-dehydrogenase, putative; n=... 87 3e-16 UniRef50_Q1RS55 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 87 3e-16 UniRef50_Q1M6K9 Cluster: Putative short-chain dehydrogenase/redu... 87 3e-16 UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogena... 87 3e-16 UniRef50_A6EBP7 Cluster: Short chain dehydrogenase; n=1; Pedobac... 87 3e-16 UniRef50_A1SPY4 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_P0A9Q0 Cluster: Gluconate 5-dehydrogenase; n=12; Gammap... 87 3e-16 UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin... 87 3e-16 UniRef50_Q7WBP3 Cluster: Probable short chain dehydrogenase; n=2... 87 3e-16 UniRef50_Q53W85 Cluster: Oxidoreductase, short-chain dehydrogena... 87 3e-16 UniRef50_Q3WJB3 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 87 3e-16 UniRef50_A3PW05 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 87 3e-16 UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=... 87 3e-16 UniRef50_UPI000023E6B9 Cluster: hypothetical protein FG02829.1; ... 87 4e-16 UniRef50_Q2K0D6 Cluster: Probable oxidoreductase protein, dehydr... 87 4e-16 UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentispha... 87 4e-16 UniRef50_Q01JQ2 Cluster: H0523F07.11 protein; n=4; Oryza sativa|... 87 4e-16 UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1... 87 4e-16 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 87 4e-16 UniRef50_P50199 Cluster: Gluconate 5-dehydrogenase; n=35; Bacter... 87 4e-16 UniRef50_Q89V28 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 86 6e-16 UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena... 86 6e-16 UniRef50_Q74T42 Cluster: Gluconate 5-dehydrogenase; n=17; Gammap... 86 6e-16 UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR... 86 6e-16 UniRef50_A6UKV7 Cluster: Short-chain dehydrogenase/reductase SDR... 86 6e-16 UniRef50_A4FJJ0 Cluster: Short-chain dehydrogenase/reductase SDR... 86 6e-16 UniRef50_A7QCC5 Cluster: Chromosome undetermined scaffold_77, wh... 86 6e-16 UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; ... 86 6e-16 UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-su... 86 8e-16 UniRef50_Q0RYG2 Cluster: Oxidoreductase; n=1; Rhodococcus sp. RH... 86 8e-16 UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesioc... 86 8e-16 UniRef50_A5VEE8 Cluster: Short-chain dehydrogenase/reductase SDR... 86 8e-16 UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR... 86 8e-16 UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reducta... 86 8e-16 UniRef50_Q8FV67 Cluster: 2-deoxy-d-gluconate 3-dehydrogenase, pu... 85 1e-15 UniRef50_Q7UEZ4 Cluster: 1-cyclohexenylcarbonyl CoA reductase-sh... 85 1e-15 UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder... 85 1e-15 UniRef50_Q0K243 Cluster: Short chain dehydrogenase; n=3; Cupriav... 85 1e-15 UniRef50_A1UGA6 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A1DLG7 Cluster: Short-chain dehydrogenase/reductase, pu... 85 1e-15 UniRef50_Q815Q6 Cluster: Short chain dehydrogenase; n=1; Bacillu... 85 1e-15 UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 85 1e-15 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 85 1e-15 UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 85 1e-15 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 85 2e-15 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 85 2e-15 UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_A5USD0 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_A1BBU8 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q9FJP5 Cluster: Similarity to dehydrogenase; n=9; core ... 85 2e-15 UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 84 2e-15 UniRef50_Q982J8 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 84 2e-15 UniRef50_Q7UPP3 Cluster: Gluconate 5-dehydrogenase; n=1; Pirellu... 84 2e-15 UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR... 84 2e-15 UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 84 2e-15 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 84 2e-15 UniRef50_A4AIS2 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 84 2e-15 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 84 2e-15 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 84 2e-15 UniRef50_A7RYX9 Cluster: Predicted protein; n=1; Nematostella ve... 84 2e-15 UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|... 84 2e-15 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 84 3e-15 UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;... 84 3e-15 UniRef50_A7MMI9 Cluster: Putative uncharacterized protein; n=1; ... 84 3e-15 UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_A6G9T9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 84 3e-15 UniRef50_A1W2L0 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q3EBY4 Cluster: Uncharacterized protein At2g17845.1; n=... 84 3e-15 UniRef50_A7D6X0 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 83 4e-15 UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR... 83 4e-15 UniRef50_A6ERE9 Cluster: Short-chain dehydrogenase/reductase SDR... 83 4e-15 UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR... 83 4e-15 UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep:... 83 4e-15 UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re... 83 4e-15 UniRef50_A6RBN3 Cluster: Predicted protein; n=1; Ajellomyces cap... 83 4e-15 UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 83 4e-15 UniRef50_Q1GX18 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 83 6e-15 UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 83 6e-15 UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_A7RXH2 Cluster: Predicted protein; n=1; Nematostella ve... 83 6e-15 UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6... 83 7e-15 UniRef50_Q46NM9 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q01ZR5 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_A5VE52 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_A5UT09 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p... 83 7e-15 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_UPI000038E4B9 Cluster: hypothetical protein Faci_030005... 82 1e-14 UniRef50_Q83BJ4 Cluster: Oxidoreductase, short chain dehydrogena... 82 1e-14 UniRef50_Q2T2R4 Cluster: Polyketide synthase, putative; n=1; Bur... 82 1e-14 UniRef50_Q3E250 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q1WVR8 Cluster: Short chain dehydrogenase; n=1; Lactoba... 82 1e-14 UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena... 82 1e-14 UniRef50_A1SMM6 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 82 1e-14 UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 82 1e-14 UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chai... 82 1e-14 UniRef50_P73991 Cluster: Short-chain alcohol dehydrogenase famil... 82 1e-14 UniRef50_Q1YRW1 Cluster: Pteridine reductase; n=1; gamma proteob... 82 1e-14 UniRef50_A6ULD1 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A3SDF7 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A1ZSH9 Cluster: Oxidoreductase, short-chain dehydrogena... 82 1e-14 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 81 2e-14 UniRef50_Q5KZY0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 81 2e-14 UniRef50_Q0SCM6 Cluster: Probable short chain dehydrogenase; n=1... 81 2e-14 UniRef50_Q44MJ4 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A1SP95 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A0V473 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specifici... 81 2e-14 UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas... 81 2e-14 UniRef50_Q82VC9 Cluster: Short-chain dehydrogenase/reductase (SD... 81 2e-14 UniRef50_Q629N6 Cluster: Putative polyketide synthase; n=11; Bur... 81 2e-14 UniRef50_Q840C9 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 81 2e-14 UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; ... 81 2e-14 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A6UFI1 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A1WDR0 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A1RDP9 Cluster: Oxidoreductase, short chain dehydrogena... 81 2e-14 UniRef50_A1HSQ5 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A0QVD4 Cluster: Dehydrogenase/reductase SDR family prot... 81 2e-14 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 81 2e-14 UniRef50_Q0CBP4 Cluster: Putative uncharacterized protein; n=2; ... 81 2e-14 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q89PM9 Cluster: Blr3451 protein; n=2; Alphaproteobacter... 81 3e-14 UniRef50_Q7VV50 Cluster: Probable short chain dehydrogenase; n=1... 81 3e-14 UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenas... 81 3e-14 UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 81 3e-14 UniRef50_Q0SBJ1 Cluster: Probable short chain dehydrogenase; n=1... 81 3e-14 UniRef50_A7HL35 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A4E7X7 Cluster: Putative uncharacterized protein; n=2; ... 81 3e-14 UniRef50_A3I430 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 81 3e-14 UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 81 3e-14 UniRef50_Q47QD3 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 80 4e-14 UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_Q1M6N2 Cluster: Putative short-chain dehydrogenase/redu... 80 4e-14 UniRef50_Q1FGW1 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|... 80 4e-14 UniRef50_A6W647 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_A3VWL9 Cluster: Putative 5-keto-D-gluconate 5-reductase... 80 4e-14 UniRef50_A3VA26 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_A1ULI4 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_A0R0K6 Cluster: Glucose-1-dehydrogenase; n=2; Mycobacte... 80 4e-14 UniRef50_Q1DSR4 Cluster: Putative uncharacterized protein; n=1; ... 80 4e-14 UniRef50_Q0CF34 Cluster: Putative uncharacterized protein; n=1; ... 80 4e-14 UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M... 80 4e-14 UniRef50_Q05528 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 80 4e-14 UniRef50_Q6MNA7 Cluster: Putative oxidoreductase; n=1; Bdellovib... 80 5e-14 UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena... 80 5e-14 UniRef50_Q396I4 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f... 80 5e-14 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 80 5e-14 UniRef50_Q1ASH3 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 80 5e-14 UniRef50_Q01ZI6 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_A6AT01 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 80 5e-14 UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_A1T1X3 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 80 5e-14 UniRef50_Q97WD7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 80 5e-14 UniRef50_Q6L1W9 Cluster: Dehydrogenase; n=1; Picrophilus torridu... 80 5e-14 UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family memb... 80 5e-14 UniRef50_Q9PDC2 Cluster: Pteridine reductase 1; n=11; Xanthomona... 79 7e-14 UniRef50_Q8YVU0 Cluster: All1884 protein; n=3; Bacteria|Rep: All... 79 7e-14 UniRef50_Q7W6W0 Cluster: Putative dehydrogenase; n=2; Bordetella... 79 7e-14 UniRef50_Q4K7Y8 Cluster: Oxidoreductase, short-chain dehydrogena... 79 7e-14 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 79 7e-14 UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ... 79 7e-14 UniRef50_Q1YII7 Cluster: Possible short-chain dehydrogenase/redu... 79 7e-14 UniRef50_Q1AYC7 Cluster: Short-chain dehydrogenase/reductase SDR... 79 7e-14 UniRef50_A3QCS8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 7e-14 UniRef50_A3HUJ4 Cluster: NAD dependent epimerase/dehydratase fam... 79 7e-14 UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 79 7e-14 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 79 7e-14 UniRef50_Q4WGA6 Cluster: Alcohol dehydrogenase; n=18; cellular o... 79 7e-14 UniRef50_A2QLP6 Cluster: Contig An06c0090, complete genome; n=1;... 79 7e-14 UniRef50_Q7MWE6 Cluster: Oxidoreductase, short chain dehydrogena... 79 9e-14 UniRef50_Q5LVV0 Cluster: Gluconate 5-dehydrogenase; n=17; Bacter... 79 9e-14 UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1; Microm... 79 9e-14 UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_A4CNY8 Cluster: Dehydrogenase; n=2; Bacteroidetes|Rep: ... 79 9e-14 UniRef50_A3K7Y9 Cluster: Oxidoreductase, short-chain dehydrogena... 79 9e-14 UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-... 79 9e-14 UniRef50_A1CZT4 Cluster: Oxidoreductase, short chain dehydrogena... 79 9e-14 UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 79 9e-14 UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 79 1e-13 UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 79 1e-13 UniRef50_Q6FBA5 Cluster: Putative oxidoreductase, short-chain de... 79 1e-13 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q41CQ8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q2CEF3 Cluster: Dehydrogenase; n=1; Oceanicola granulos... 79 1e-13 UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 79 1e-13 UniRef50_Q0SD55 Cluster: Possible short chain oxidoreductase; n=... 79 1e-13 UniRef50_A5UTC3 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A5USZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A5FF05 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A3XEC4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 79 1e-13 UniRef50_A0L6T4 Cluster: Acetoacetyl-CoA reductase; n=24; Bacter... 79 1e-13 UniRef50_A0JVY9 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q9VJG8 Cluster: CG6012-PA; n=2; Sophophora|Rep: CG6012-... 79 1e-13 UniRef50_Q6BVQ9 Cluster: Debaryomyces hansenii chromosome C of s... 79 1e-13 UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family memb... 79 1e-13 UniRef50_UPI00003C857D Cluster: hypothetical protein Faci_030002... 78 2e-13 UniRef50_Q9KCQ9 Cluster: Oxidoreductase; n=10; Firmicutes|Rep: O... 78 2e-13 UniRef50_Q97SL2 Cluster: Oxidoreductase, short chain dehydrogena... 78 2e-13 UniRef50_Q93H96 Cluster: Putative oxidoreductase; n=1; Streptomy... 78 2e-13 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 78 2e-13 UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc... 78 2e-13 UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogena... 78 2e-13 UniRef50_Q9KHD1 Cluster: Putative beta-ketoacyl reductase; n=1; ... 78 2e-13 UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str... 78 2e-13 UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A5Z530 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13 UniRef50_A5V821 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A5UX97 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A3U137 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A3Q4Y4 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A3K762 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A1UBR0 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A1G626 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q2UP16 Cluster: RIB40 genomic DNA, SC001; n=3; Aspergil... 78 2e-13 UniRef50_A2QME7 Cluster: Catalytic activity: scytalone + NADP(+)... 78 2e-13 UniRef50_A2QIH4 Cluster: Contig An04c0140, complete genome; n=16... 78 2e-13 UniRef50_Q97BK9 Cluster: Alcohol dehydrogenase [ADH]; n=3; Therm... 78 2e-13 UniRef50_A0RXB6 Cluster: Short-chain alcohol dehydrogenase; n=2;... 78 2e-13 UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein,... 78 2e-13 UniRef50_UPI0000DB7181 Cluster: PREDICTED: similar to CG1444-PA;... 78 2e-13 UniRef50_Q983U4 Cluster: Putative dehydrogenase; n=1; Mesorhizob... 78 2e-13 UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=... 78 2e-13 UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Al... 78 2e-13 UniRef50_Q7NCZ3 Cluster: Gll2833 protein; n=1; Gloeobacter viola... 78 2e-13 UniRef50_Q2CJE2 Cluster: Short chain dehydrogenase; n=1; Oceanic... 78 2e-13 UniRef50_Q0K556 Cluster: Short chain dehydrogenase; n=1; Ralston... 78 2e-13 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A1UBL5 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A0K061 Cluster: Rhamnulose-1-phosphate aldolase/alcohol... 78 2e-13 UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 78 2e-13 UniRef50_Q5YXU5 Cluster: Putative short chain dehydrogenase; n=1... 77 3e-13 UniRef50_Q4KG49 Cluster: Oxidoreductase, short chain dehydrogena... 77 3e-13 UniRef50_Q46MU1 Cluster: NAD-dependent epimerase/dehydratase:Sho... 77 3e-13 UniRef50_Q3W5I4 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q2CJE1 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho... 77 3e-13 UniRef50_Q126E9 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q11QG7 Cluster: Short-chain alcohol-related dehydrogena... 77 3e-13 UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba... 77 3e-13 UniRef50_Q04HJ3 Cluster: 3-oxoacyl-acyl carrier protein reductas... 77 3e-13 UniRef50_Q03U43 Cluster: Short-chain alcohol dehydrogenase; n=4;... 77 3e-13 UniRef50_A7MP24 Cluster: Putative uncharacterized protein; n=1; ... 77 3e-13 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 77 3e-13 UniRef50_A4BRT2 Cluster: Probable oxidoreductase; n=1; Nitrococc... 77 3e-13 UniRef50_A1G918 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_A0UJ74 Cluster: Beta-ketoacyl synthase; n=2; Bacteria|R... 77 3e-13 UniRef50_A0QH10 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_A0JT69 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q6KZE3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 77 3e-13 UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 77 3e-13 UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 77 4e-13 UniRef50_Q7CHE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 77 4e-13 UniRef50_Q67RA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 4e-13 UniRef50_Q48GA0 Cluster: Gluconate 5-dehydrogenase, putative; n=... 77 4e-13 UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q5KRB0 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 4e-13 UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein... 77 4e-13 UniRef50_Q2CJ65 Cluster: Polyketide synthase, putative; n=1; Oce... 77 4e-13 UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain dehydrogena... 77 4e-13 UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 4e-13 UniRef50_A3Q3U6 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q236S0 Cluster: Oxidoreductase, short chain dehydrogena... 77 4e-13 UniRef50_Q5ANM3 Cluster: Likely dihydroxyacetone phosphate reduc... 77 4e-13 UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 77 4e-13 UniRef50_P0AET9 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 77 4e-13 UniRef50_Q7ND89 Cluster: Gll4347 protein; n=3; Cyanobacteria|Rep... 77 5e-13 UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogena... 77 5e-13 UniRef50_Q63IK1 Cluster: Short chain dehydrogenase; n=6; Proteob... 77 5e-13 UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 77 5e-13 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 77 5e-13 UniRef50_Q3E683 Cluster: NAD-dependent epimerase/dehydratase:Sho... 77 5e-13 UniRef50_Q1CYK0 Cluster: Putative 3-oxoacyl-(Acyl-carrier-protei... 77 5e-13 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_Q1AU84 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A6CPA0 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A5V849 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A5FER5 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A4YXA7 Cluster: Putative 3-oxoacyl-[acyl-carrier-protei... 77 5e-13 UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A3IAI0 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_P14697 Cluster: Acetoacetyl-CoA reductase; n=25; Bacter... 77 5e-13 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 77 5e-13 UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 77 5e-13 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 76 6e-13 UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 76 6e-13 UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 76 6e-13 UniRef50_Q62JY9 Cluster: Acetoacetyl-CoA reductase; n=58; cellul... 76 6e-13 UniRef50_Q5LDH2 Cluster: Putative 2,5-dichloro-2,5-cyclohexadien... 76 6e-13 UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact... 76 6e-13 UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 76 6e-13 UniRef50_Q1M371 Cluster: Putative short-chain dehydrogenase/oxid... 76 6e-13 UniRef50_A0R386 Cluster: Dehydrogenase/reductase SDR family prot... 76 6e-13 UniRef50_Q9YDK1 Cluster: Putative dehydrogenase; n=1; Aeropyrum ... 76 6e-13 UniRef50_Q9HLN6 Cluster: Probable glucose 1-dehydrogenase; n=4; ... 76 6e-13 UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 76 6e-13 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 76 6e-13 UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 76 6e-13 UniRef50_Q9BUT1 Cluster: 3-hydroxybutyrate dehydrogenase type 2;... 76 6e-13 UniRef50_UPI000023F218 Cluster: hypothetical protein FG03404.1; ... 76 8e-13 UniRef50_Q98C97 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 76 8e-13 UniRef50_Q73Q46 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 76 8e-13 UniRef50_Q72L28 Cluster: Gluconate 5-dehydrogenase; n=2; Thermus... 76 8e-13 UniRef50_Q63M96 Cluster: Short chain dehydrogenase; n=34; Bacter... 76 8e-13 UniRef50_Q39N10 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_Q2JVU3 Cluster: Oxidoreductase, short chain dehydrogena... 76 8e-13 UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc... 76 8e-13 UniRef50_Q28JT5 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_Q12AF9 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_Q02B17 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 76 8e-13 UniRef50_A2ULL1 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ... 76 8e-13 UniRef50_A0NSD0 Cluster: Ketoreductase; n=1; Stappia aggregata I... 76 8e-13 UniRef50_Q54PT0 Cluster: Putative uncharacterized protein; n=1; ... 76 8e-13 UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 76 8e-13 UniRef50_Q9AK65 Cluster: Putative glucose 1-dehydrogenase; n=2; ... 75 1e-12 UniRef50_Q8KAS0 Cluster: Oxidoreductase, short-chain dehydrogena... 75 1e-12 UniRef50_Q82MI1 Cluster: Putative dehydrogenase; n=1; Streptomyc... 75 1e-12 UniRef50_Q7NDN2 Cluster: Gll4203 protein; n=2; Bacteria|Rep: Gll... 75 1e-12 UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 75 1e-12 UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta... 75 1e-12 UniRef50_Q28RW9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 75 1e-12 UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 75 1e-12 UniRef50_Q1GSP0 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q0M3P6 Cluster: NAD-dependent epimerase/dehydratase:Sho... 75 1e-12 UniRef50_Q0BR82 Cluster: Short chain dehydrogenase; n=1; Granuli... 75 1e-12 UniRef50_A7D028 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A6W3U8 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A5V6W3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A5L8A4 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A4WBV5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A3SL40 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12 UniRef50_A3D7Y4 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A1AYG8 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A0HKD2 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q9W4U2 Cluster: CG3603-PA; n=8; Neoptera|Rep: CG3603-PA... 75 1e-12 UniRef50_Q6CNU5 Cluster: Similar to sp|Q9ALU7 Enterobacter cloac... 75 1e-12 UniRef50_Q2U1J7 Cluster: RIB40 genomic DNA, SC011; n=1; Aspergil... 75 1e-12 UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 75 1e-12 UniRef50_UPI000038DFB9 Cluster: hypothetical protein Faci_030015... 75 1e-12 UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogena... 75 1e-12 UniRef50_Q826D4 Cluster: Putative 3-oxoacyl-ACP reductase; n=1; ... 75 1e-12 UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 75 1e-12 UniRef50_Q5GZM4 Cluster: 3-oxoacyl-reductase; n=5; Proteobacteri... 75 1e-12 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 75 1e-12 UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q0RIJ2 Cluster: Putative short chain dehydrogenase/redu... 75 1e-12 UniRef50_A7HGD6 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A6VSM3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 >UniRef50_Q567K5 Cluster: Zgc:111977; n=14; Coelomata|Rep: Zgc:111977 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 244 Score = 232 bits (568), Expect = 5e-60 Identities = 111/202 (54%), Positives = 145/202 (71%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 214 MEISF+GKR LVT L R G+ + A++RT++ L+SL E PSI V VD Sbjct: 1 MEISFRGKRALVTGAGKGIGRATALALARCGSEVTAVTRTKADLDSLVQECPSIKPVCVD 60 Query: 215 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 + DW+ T++ + ++G D LVNNAA A +PFLD +P FD +F++NVKA L+++Q+VAR Sbjct: 61 LSDWDATKEALNNVGPVDLLVNNAACAKLQPFLDVTPDQFDMSFNINVKAALHVAQIVAR 120 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 M T G+IVN+SSQAS+ ALKDH +Y A+KAALD LTR MALELGP+ IRVN++NPT Sbjct: 121 GMKARGTGGSIVNVSSQASQCALKDHAVYCATKAALDMLTRVMALELGPHQIRVNSVNPT 180 Query: 575 VIMTEMAKVGWSDPIKANEMLS 640 V+MTEM K+GWSDP KA M S Sbjct: 181 VVMTEMGKIGWSDPEKARSMTS 202 >UniRef50_Q7Z4W1 Cluster: L-xylulose reductase; n=37; Coelomata|Rep: L-xylulose reductase - Homo sapiens (Human) Length = 244 Score = 211 bits (516), Expect = 9e-54 Identities = 101/202 (50%), Positives = 141/202 (69%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 214 ME+ G+R+LVT L GA +VA+SRT++ L+SL E P I+ V VD Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60 Query: 215 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 +GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 +I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180 Query: 575 VIMTEMAKVGWSDPIKANEMLS 640 V+MT M + WSDP KA ML+ Sbjct: 181 VVMTSMGQATWSDPHKAKTMLN 202 >UniRef50_A7S0F0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 210 Score = 173 bits (422), Expect = 2e-42 Identities = 90/188 (47%), Positives = 122/188 (64%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 214 MEISFKGKR LVT L R GA +VA+SRT++ L+SL+ E PSI V D Sbjct: 1 MEISFKGKRALVTGAGKGIGRGVAKALVRCGAEVVAISRTKADLDSLRDEVPSIQAVCDD 60 Query: 215 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 + D EK +K++ES FD LVNNA A+ E FL+ P +FD+ + NV+A L I+Q VA+ Sbjct: 61 VADIEKMQKLIESQETFDLLVNNAGFAIFESFLEIKPESFDRMHETNVRAPLFIAQAVAK 120 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 KM+ GAIVN+SS ++ L + ++KAA+D +T+ MA+ELG Y IRVN +NPT Sbjct: 121 KMVAKGEGGAIVNVSSVFTELHLPNSISLVSNKAAMDRMTKGMAMELGHYKIRVNTVNPT 180 Query: 575 VIMTEMAK 598 V+ T+ AK Sbjct: 181 VVWTDAAK 188 >UniRef50_Q201Y9 Cluster: Putative diacetyl/L-xylulose reductase; n=3; Aphidinae|Rep: Putative diacetyl/L-xylulose reductase - Acyrthosiphon pisum (Pea aphid) Length = 241 Score = 165 bits (402), Expect = 6e-40 Identities = 84/201 (41%), Positives = 117/201 (58%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 214 ME FKGK+ +VT L G+ + A+ E P+ + D Sbjct: 1 MEDYFKGKKFIVTGSCAGMGEKITERLVDLGSFVYAVVEKE---EGAAKALPNTKQIFCD 57 Query: 215 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 + +WE T K + +G LVNNA VAV EPF D + +DKT ++N +A++ ISQ VA+ Sbjct: 58 VSNWEDTYKKMYDIGPVHGLVNNAGVAVIEPFFDVTEHGWDKTLNINARALVRISQAVAK 117 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 MI+ G+IVNISS S A+ DHT Y ASK A++ +TR MA+ELG YGIR N +NPT Sbjct: 118 NMIDAGIKGSIVNISSTISTRAIPDHTTYCASKGAVNQITRTMAIELGKYGIRTNNVNPT 177 Query: 575 VIMTEMAKVGWSDPIKANEML 637 V++T M K+ WSDP K+ ++ Sbjct: 178 VVLTRMGKIAWSDPEKSGPIM 198 >UniRef50_Q8SYA6 Cluster: RH08058p; n=5; Diptera|Rep: RH08058p - Drosophila melanogaster (Fruit fly) Length = 242 Score = 158 bits (384), Expect = 9e-38 Identities = 83/197 (42%), Positives = 123/197 (62%), Gaps = 1/197 (0%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-SIDIVDVDIGDWE 229 GK ILVT +L AGA ++A++R L+ L + P I + +D+ W+ Sbjct: 7 GKVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDPVHIQPLQLDLSGWQ 66 Query: 230 KTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN 409 R+ + + D LVNNA VA+ +PF + + +FD FDVN+KAV N++Q + ++ Sbjct: 67 AVREGLAKVPLLDGLVNNAGVAIIKPFEELTEQDFDTHFDVNIKAVFNVTQSLLPRL--- 123 Query: 410 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 589 K +IVN+SS AS + HT YSA+KAALD+LT+++ALELGP IRVN+INPTV++T+ Sbjct: 124 KDGASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSINPTVVLTK 183 Query: 590 MAKVGWSDPIKANEMLS 640 M WSDP K+ +L+ Sbjct: 184 MGADNWSDPAKSGPLLA 200 >UniRef50_Q21929 Cluster: Probable L-xylulose reductase; n=3; Bilateria|Rep: Probable L-xylulose reductase - Caenorhabditis elegans Length = 251 Score = 150 bits (364), Expect = 2e-35 Identities = 86/202 (42%), Positives = 119/202 (58%), Gaps = 5/202 (2%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI-GD 223 F KRILVT L +AGA ++A +R ++L SL E S+ + I GD Sbjct: 7 FTDKRILVTGASQGIGKEICLSLAKAGAQVIAFARNEANLLSLVKETTSLRYTIIPIVGD 66 Query: 224 WEKTRKVVESL--GHFD--ALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 +V+ L HF LVNNA +A + + D+TF VNV+ + I+Q+VA Sbjct: 67 VSANEEVLFKLIVPHFPIHGLVNNAGIATNHAIGQITQQSIDRTFAVNVRGPILIAQLVA 126 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 R ++ + G+IVNISSQA+ L +HT+Y ASKAALD +TR +A ELG IRVN++NP Sbjct: 127 RNFVDRQIKGSIVNISSQAAIRPLDNHTVYCASKAALDMVTRCLANELGSQNIRVNSVNP 186 Query: 572 TVIMTEMAKVGWSDPIKANEML 637 TV+MT+M + WSDP K +ML Sbjct: 187 TVVMTDMGRDNWSDPDKKKKML 208 >UniRef50_Q7CUM7 Cluster: AGR_L_1073p; n=6; Alphaproteobacteria|Rep: AGR_L_1073p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 270 Score = 150 bits (363), Expect = 3e-35 Identities = 79/199 (39%), Positives = 114/199 (57%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIG 220 + F GK +++T + GA +VA+SRT+S L+SL+SE I VD+ Sbjct: 30 MQFSGKSVIITGAGKGIGRACAQLMAARGAEVVAISRTQSDLDSLKSEIGGRSI-RVDLA 88 Query: 221 DWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 D TR + G D L+N+A + V E LD S + ++ +N++A L Q AR Sbjct: 89 DIAATRAAMAEAGPCDFLINSAGINVLESVLDMSDAGYEAVLGINLRAALVTCQEFARGR 148 Query: 401 IENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVI 580 + N GAIVNI+S A +DH Y+ASKA L+ TR +A ELGP+GIRVNA+ PT+ Sbjct: 149 VANGGGGAIVNITSIAGHRGFQDHLCYAASKAGLEGATRVLAKELGPHGIRVNAVAPTIT 208 Query: 581 MTEMAKVGWSDPIKANEML 637 +TE+A W+DP K+ M+ Sbjct: 209 LTELAAEAWNDPEKSQPMM 227 >UniRef50_UPI0000E46E8D Cluster: PREDICTED: similar to dicarbonyl/L-xylulose reductase, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dicarbonyl/L-xylulose reductase, partial - Strongylocentrotus purpuratus Length = 228 Score = 149 bits (360), Expect = 7e-35 Identities = 71/176 (40%), Positives = 116/176 (65%) Frame = +2 Query: 113 LWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAV 292 L + GA++ AL+R+++ L++L+ E P I+ + +D+ DW+KT +V+ L FD LVN+A V Sbjct: 9 LAKCGASVTALTRSQADLDTLKQEVPGIETICLDVHDWDKTNEVLSPLPPFDLLVNSAGV 68 Query: 293 AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDH 472 + E L+ S +D +N +A+L I+++VA+ MI G+IVN+SS AS L +H Sbjct: 69 SSGESCLEVSAEAYDNVMMINHRAILQITKIVAKGMIAKGEGGSIVNLSSIASLQGLTNH 128 Query: 473 TIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKANEMLS 640 +Y++SK ALD+ T+ ALEL + IRVN +NPTV++T MA+ W+ + M++ Sbjct: 129 AVYASSKGALDSYTKVAALELAKHKIRVNCVNPTVVLTPMARKFWAQGEMRDAMIN 184 >UniRef50_Q92MT5 Cluster: PUTATIVE OXIDOREDUCTASE PROTEIN; n=2; Rhizobiaceae|Rep: PUTATIVE OXIDOREDUCTASE PROTEIN - Rhizobium meliloti (Sinorhizobium meliloti) Length = 241 Score = 140 bits (339), Expect = 3e-32 Identities = 79/199 (39%), Positives = 107/199 (53%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIG 220 + F GK ++VT L GA +VALSRT+S L+ L S+ IV D+ Sbjct: 1 MEFSGKSVIVTGGGKGIGRATVALLAARGAQVVALSRTQSDLDELSSQTGCHGIV-ADLA 59 Query: 221 DWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 D R + G D LVN A V E +D + +D + N++A L +Q AR Sbjct: 60 DAAAARAAMVEAGTCDILVNCAGTNVLESLIDMTDDGYDVVMNTNLRAALICAQEFARAR 119 Query: 401 IENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVI 580 + GAIVN++S A ++H Y+ASKA L+ TR MA ELGPYGIRV AI PT+ Sbjct: 120 MAAGGGGAIVNVTSIAGHRGFQNHVCYAASKAGLEGATRVMAKELGPYGIRVVAIAPTIT 179 Query: 581 MTEMAKVGWSDPIKANEML 637 MTE+A W+DP K+ M+ Sbjct: 180 MTELAAAAWADPQKSEPMM 198 >UniRef50_Q62K95 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=34; cellular organisms|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Burkholderia mallei (Pseudomonas mallei) Length = 248 Score = 140 bits (339), Expect = 3e-32 Identities = 78/207 (37%), Positives = 111/207 (53%), Gaps = 3/207 (1%) Frame = +2 Query: 29 LKMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD 208 + + F G+ LVT L GA +VA +R LE L E + ++ Sbjct: 1 MSVAFDFHGRSFLVTGASSGIGRAAAVALRGGGARVVAAARNARELERLAHE-TGCEPLE 59 Query: 209 VDIGDWEKTRKVVES---LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 +D+G R + FD L+N A V +D + FD+ VN + + ++ Sbjct: 60 LDVGCDASVRAALSGERMRDAFDGLINCAGVTSLAAAIDTTADEFDRVMAVNARGAMLVA 119 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + VAR MI G+IVN+SSQA+ AL H Y ASKAALDA+TR + +ELGP+GIRVN Sbjct: 120 RHVARAMIRAGRGGSIVNVSSQAALVALPSHLAYCASKAALDAMTRVLCVELGPHGIRVN 179 Query: 560 AINPTVIMTEMAKVGWSDPIKANEMLS 640 ++NPTV +T MA+ WSDP + ML+ Sbjct: 180 SVNPTVTLTPMAERAWSDPHASGPMLA 206 >UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomycetales|Rep: L-xylulose reductase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 262 Score = 122 bits (293), Expect = 1e-26 Identities = 71/205 (34%), Positives = 107/205 (52%), Gaps = 9/205 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQ---SEYPSIDI--VDVDI 217 GKR L+T AGA +V R S L++ + E D+ V +D+ Sbjct: 16 GKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVAIDL 75 Query: 218 GD----WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + E R+ E+ G D LVNNA ++ +P +D P FD T VN++A ++ Sbjct: 76 AEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALLASA 135 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 V + M+ GAI+ ++S A+ A L DH Y SKA L T+ +A ELGP+GIR N++ Sbjct: 136 VGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSV 195 Query: 566 NPTVIMTEMAKVGWSDPIKANEMLS 640 PTV++TEM + W D K+ M++ Sbjct: 196 CPTVVLTEMGQRVWGDEAKSAPMIA 220 >UniRef50_UPI0001555DAD Cluster: PREDICTED: similar to dicarbonyl/L-xylulose reductase; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to dicarbonyl/L-xylulose reductase - Ornithorhynchus anatinus Length = 400 Score = 116 bits (279), Expect = 5e-25 Identities = 52/100 (52%), Positives = 72/100 (72%) Frame = +2 Query: 188 PSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAV 367 P I+ V VD+G WE T K + +G D LVNNA VA+ +PFLD + FD +F+VN+++V Sbjct: 249 PGIETVCVDLGSWEATEKALADVGPVDLLVNNAGVALLQPFLDVTKEAFDTSFEVNLRSV 308 Query: 368 LNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSA 487 L +SQ+VAR M+ GAIVN+SSQAS+ A++DH +YSA Sbjct: 309 LQVSQIVARGMVARGAPGAIVNVSSQASRCAVRDHAVYSA 348 >UniRef50_A0XC03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Dinoroseobacter shibae DFL 12|Rep: Short-chain dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL 12 Length = 255 Score = 112 bits (270), Expect = 6e-24 Identities = 69/207 (33%), Positives = 107/207 (51%), Gaps = 8/207 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDV 211 S + K LVT AGA+IV R L L ++ + + Sbjct: 8 SLQDKTALVTGASSGIGRAIAEVFADAGADIVGQGRDLDRLTDLGAQIKTTGRQFAAITG 67 Query: 212 DIGDWEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ D ++T+ V + + G D LVN+A +AV P + ++ +T VN+ A +S Sbjct: 68 DLADPDQTQNVADRALAAFGKIDILVNSAGIAVTGPVTNYDLDDWQRTLAVNLTAPFILS 127 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + V M++ K G I+NISSQ ALKDH Y+ SK L+ALT+++ E P+ ++VN Sbjct: 128 KAVMPGMMQRK-QGKIINISSQTGVIALKDHAAYATSKGGLNALTKSLMTEAAPHNVQVN 186 Query: 560 AINPTVIMTEMAKVGWSDPIKANEMLS 640 AI PTV++TEM K WS P + + ++ Sbjct: 187 AICPTVVLTEMGKELWSAPERKDPFIA 213 >UniRef50_A0VS96 Cluster: Short-chain dehydrogenase/reductase SDR; n=12; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL 12 Length = 262 Score = 111 bits (266), Expect = 2e-23 Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 4/194 (2%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPSIDIVDVDIG 220 G+R LVT L AGA++V +R ++ L++ +++E S++ +DI Sbjct: 24 GQRALVTGASRGIGLGCAVALAEAGAHVVMAARGQAELDAAATEMRAEGWSVETAVLDIA 83 Query: 221 DWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 D + + + FD LVN+A +A P LD P +FD VN++A ++ AR M Sbjct: 84 DLDAQAEFFGAQAPFDCLVNSAGLARHSPALDTRPEDFDAVMSVNLRAAYFLATNAARTM 143 Query: 401 IENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVI 580 + G+IV ISSQ D +Y ASK ++ +T+AMA E GP GIRVN++ PT I Sbjct: 144 PDG---GSIVQISSQMGHVGGLDRAVYCASKHGVEGMTKAMAQEFGPRGIRVNSLCPTFI 200 Query: 581 MTEMAKVGWSDPIK 622 T + + ++DP K Sbjct: 201 RTPLTEATFADPEK 214 >UniRef50_A3Z051 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Synechococcus sp. WH 5701|Rep: Short-chain dehydrogenase/reductase SDR - Synechococcus sp. WH 5701 Length = 256 Score = 110 bits (264), Expect = 3e-23 Identities = 65/196 (33%), Positives = 105/196 (53%), Gaps = 8/196 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQ----SEYPSIDIVDVDIG 220 GKR L++ AGA+I + R R L +Q + + + +++ D+ Sbjct: 8 GKRALISGGSKGLGAAIAERFSEAGADIGVIGRDREGLGRIQGIVENNHRNCWVIEEDVS 67 Query: 221 DWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 E R+ + +D LVNNA +A + L+ + N++ F VN+++ L +SQ + Sbjct: 68 SIEGARRAGDKALALDPEWDVLVNNAGIARVQSILETTQDNWNDIFSVNLRSALLLSQAI 127 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 +MI+ + HG +VNISS + Y+ASKAAL+ LTR MA+E GP+ ++VNA+ Sbjct: 128 VPQMIK-RGHGKVVNISSIGAFIGTPGLGAYAASKAALNQLTRTMAVEWGPHNVQVNALC 186 Query: 569 PTVIMTEMAKVGWSDP 616 PTVI+T+M W P Sbjct: 187 PTVILTQMGHDIWDSP 202 >UniRef50_Q62AB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=14; Burkholderiales|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Burkholderia mallei (Pseudomonas mallei) Length = 256 Score = 109 bits (262), Expect = 6e-23 Identities = 53/118 (44%), Positives = 76/118 (64%) Frame = +2 Query: 257 GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNI 436 G D LVN+A VA+ + LD + +D T +NVKA ++Q AR+MI G IVN+ Sbjct: 88 GGVDMLVNSAGVALLDKALDVGEAAWDATMAINVKASFFVAQAAARQMIAGARGGRIVNL 147 Query: 437 SSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWS 610 +SQAS L+ H Y ASKAA+ +T+A+ALE P+GI VNA++PT++ T + K W+ Sbjct: 148 ASQASVVGLERHAAYCASKAAIVGMTKALALEWAPHGITVNAVSPTIVETALGKQAWA 205 >UniRef50_Q28TD9 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Jannaschia sp. (strain CCS1) Length = 251 Score = 109 bits (262), Expect = 6e-23 Identities = 66/197 (33%), Positives = 102/197 (51%), Gaps = 4/197 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP----SIDIVDV 211 S G+R V L AGA++V +R R +++ +E S + + + Sbjct: 10 SLAGQRAFVPGGSRGIGLGCAVALAEAGAHVVIAARGRDAVDAAMAEITQAGFSAEGITL 69 Query: 212 DIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 DI D + TR V ++G D L N+A +A P D +P +FD VNV+A ++Q A Sbjct: 70 DITDVDATRAAVAAMGRLDILCNSAGLARHTPATDTTPEDFDAVQAVNVRAAYFLAQAAA 129 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 +MI+ G+I+ +SSQ D +Y A+K A++ T+AMA+E GP IRVN + P Sbjct: 130 AQMIDG---GSIIQVSSQMGHVGGIDRAVYCATKHAVEGFTKAMAIEWGPRNIRVNTLCP 186 Query: 572 TVIMTEMAKVGWSDPIK 622 T I T + ++DP K Sbjct: 187 TFIRTPLTAPTFADPEK 203 >UniRef50_A6W805 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Kineococcus radiotolerans SRS30216|Rep: Short-chain dehydrogenase/reductase SDR precursor - Kineococcus radiotolerans SRS30216 Length = 235 Score = 107 bits (258), Expect = 2e-22 Identities = 65/184 (35%), Positives = 91/184 (49%) Frame = +2 Query: 65 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKV 244 LVT L G + L RT + L LQ + D V +V Sbjct: 8 LVTGGAGGIGAAVVAALEAEGTRVAVLDRTETSLGELQVGADTTDPAQVRAA----VDEV 63 Query: 245 VESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGA 424 V G D LVN A VA P L+ + +++T VN+ ++Q VAR + + G Sbjct: 64 VARAGRLDVLVNCAGVATIAPALEIDLAGWERTVAVNLTGAFVVAQTVARHLAAHGG-GR 122 Query: 425 IVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVG 604 IV I+SQA+ L H Y+ASKA L +TR +ALE GP GI VN ++PTV++T +A+ Sbjct: 123 IVTIASQAATVGLAGHVAYAASKAGLLGMTRTLALEWGPLGITVNTVSPTVVLTPLARPN 182 Query: 605 WSDP 616 W +P Sbjct: 183 WENP 186 >UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP00000021339; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000021339 - Strongylocentrotus purpuratus Length = 242 Score = 105 bits (252), Expect = 9e-22 Identities = 53/120 (44%), Positives = 76/120 (63%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 + ++ D LVNNA V S +FDK F VNV+A L ++Q++A ++I KT Sbjct: 58 ETIQKFNQIDVLVNNAGVLTAGSVETVSLESFDKIFAVNVRAPLQLTQLLAPQLI--KTK 115 Query: 419 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 G +VN+SS K ++ D IYS SK ALD +TR++A EL P+G+RVNA+NP I+T + K Sbjct: 116 GTVVNVSSVVGKVSMPDFLIYSMSKTALDHMTRSIAEELAPHGVRVNAVNPGAIVTPIIK 175 >UniRef50_A7D2W7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Short-chain dehydrogenase/reductase SDR - Halorubrum lacusprofundi ATCC 49239 Length = 257 Score = 105 bits (251), Expect = 1e-21 Identities = 58/152 (38%), Positives = 88/152 (57%), Gaps = 3/152 (1%) Frame = +2 Query: 167 ESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHF---DALVNNAAVAVCEPFLDCSPSNFD 337 E+++ + V+ D+ D + V+E+ G F D +VNNA V FLD +P +FD Sbjct: 57 EAIEDRGGTAVFVETDVSDPTQIESVIEAAGEFGGVDVMVNNAGVHRSAEFLDVTPEDFD 116 Query: 338 KTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTR 517 VN+K +Q+ A+ MI+ G IVN SS ++ A +H+ Y+A+K + LTR Sbjct: 117 FVHGVNLKGAFFGTQLAAQDMIDRGVEGTIVNTSSTTAERAEWNHSHYAATKGGIQMLTR 176 Query: 518 AMALELGPYGIRVNAINPTVIMTEMAKVGWSD 613 + ALEL +GIRVNA+ P I TE+ + GWS+ Sbjct: 177 SAALELDRHGIRVNAVAPGPIATEI-REGWSE 207 >UniRef50_Q5KZI9 Cluster: Dehydrogenase; n=5; Bacilli|Rep: Dehydrogenase - Geobacillus kaustophilus Length = 257 Score = 104 bits (249), Expect = 2e-21 Identities = 65/204 (31%), Positives = 99/204 (48%), Gaps = 8/204 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDVDIG 220 GK LVT AGA++ ++RT + L+ S I +D+ Sbjct: 10 GKTALVTGAGRGIGRAIAIGFAEAGADVALIARTEADLQETASHIEQFGRKAYIYPLDVI 69 Query: 221 DWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 D + V ++ G D +VNNA + + P LD + ++ + N+K+ +SQ Sbjct: 70 DRKAVHDAVANVKQQAGSLDIVVNNAGMNIRTPALDVTDHEWETIMNTNLKSAFLVSQEA 129 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 R M E K G I+NI+S A AL+ +Y+A+KAAL +T+ +A E G YGIRVNAI Sbjct: 130 GRVMKEQKQGGNIINIASVAGHVALRTGVVYAATKAALIQMTKVLAFEWGRYGIRVNAIG 189 Query: 569 PTVIMTEMAKVGWSDPIKANEMLS 640 P T + K D N++L+ Sbjct: 190 PWYFRTPLTKTLLEDEAYVNDILA 213 >UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 255 Score = 101 bits (243), Expect = 1e-20 Identities = 66/193 (34%), Positives = 98/193 (50%), Gaps = 8/193 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI----VDV 211 S KGK +VT L AGAN+V SR + + + SE S + V Sbjct: 7 SLKGKTAIVTGASQGLGEAMALGLAEAGANLVLASRNEASMAKVASEVTSKGVQCLTVKT 66 Query: 212 DIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ + + +V+ G D LVNNA + + +PF++ + ++D D N+K S Sbjct: 67 DMLKADDIQAMVDKGIAQFGTIDILVNNAGINLVKPFVNLTEEDWDSVVDTNLKGYFLCS 126 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 QVV R+MI+NK +G ++N +S + Y ASK + LTR +A+E + IRVN Sbjct: 127 QVVGREMIKNK-NGCVINNASVFGLRGFPNIASYIASKGGVVQLTRGLAVEWARHNIRVN 185 Query: 560 AINPTVIMTEMAK 598 I P I+TEMAK Sbjct: 186 CIAPGYIVTEMAK 198 >UniRef50_UPI00005BF380 Cluster: PREDICTED: similar to dicarbonyl/L-xylulose reductase isoform 3; n=1; Bos taurus|Rep: PREDICTED: similar to dicarbonyl/L-xylulose reductase isoform 3 - Bos taurus Length = 189 Score = 101 bits (241), Expect = 2e-20 Identities = 48/117 (41%), Positives = 72/117 (61%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 214 M++ G+R LVT L AGA +VA+SRT++ L+SL E P ++ V VD Sbjct: 1 MDLRLAGRRALVTGAGKGIGRSIVKALHAAGARVVAVSRTQADLDSLVRECPGVETVCVD 60 Query: 215 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + DWE T + + +G D LVNNAAVA +PFL+ + +D +F VN++AV+ +SQ+ Sbjct: 61 LADWEATEQALGGVGPVDLLVNNAAVAFLQPFLEVTKEAYDMSFSVNLRAVIQVSQI 117 Score = 47.6 bits (108), Expect = 3e-04 Identities = 20/30 (66%), Positives = 23/30 (76%) Frame = +2 Query: 548 IRVNAINPTVIMTEMAKVGWSDPIKANEML 637 IRVNA+NPTV+MT M + WSDP KA ML Sbjct: 117 IRVNAVNPTVVMTPMGQAAWSDPQKAKAML 146 >UniRef50_Q7WPV2 Cluster: Short chain dehydrogenase; n=2; Bordetella|Rep: Short chain dehydrogenase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 250 Score = 101 bits (241), Expect = 2e-20 Identities = 66/188 (35%), Positives = 95/188 (50%), Gaps = 8/188 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQ---SEYPSIDIVDV-DIG 220 GK LVT L +AGAN+V R ++ LE + EY +D DI Sbjct: 6 GKTALVTGASRGIGQNVALCLAQAGANVVLWGRDQAELEQTRVRIDEYGVQSTIDAFDIT 65 Query: 221 DWEKTRKV----VESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 + E R+ +E GH D LV NA V V PFLD +P +D VN+ ++ Q V Sbjct: 66 EAESVRRATAQAIERFGHLDVLVVNAGVNVLRPFLDWTPQQWDHMIGVNLVGAMHTLQAV 125 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 R M E K G+I+ +SS S D+++Y +K L LT+++A+E + +RVNAI Sbjct: 126 GRHMTERK-QGSIITMSSIYSHVGAPDNSVYCLTKGGLLQLTKSLAMEWARHKVRVNAIC 184 Query: 569 PTVIMTEM 592 P I T++ Sbjct: 185 PGWIETDL 192 >UniRef50_Q0RYT4 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Rhodococcus sp. RHA1|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 260 Score = 99.5 bits (237), Expect = 6e-20 Identities = 68/197 (34%), Positives = 96/197 (48%), Gaps = 7/197 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVA--LSRTRSHLESLQSE-YPSIDIVDVD 214 + + K +VT EL GA +V L +LQS P VD Sbjct: 3 TLENKIAIVTGASRGLGEGIAVELAARGATVVCADLHSAEDTATTLQSAGSPKSSSAKVD 62 Query: 215 IGDW----EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 + E VE+ G D +VNNA + D + +F +T DVN+ V N S+ Sbjct: 63 VSSAASVDELVGSTVETHGRLDIMVNNAGIYTYGAIADVTDDDFRRTMDVNIGGVFNGSR 122 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 AR M E K+ G I+N +SQ K A + +YSASKAA+ +T+A+ LEL PY I VNA Sbjct: 123 AAARVMKEQKS-GRIINTASQLGKLARPNEGVYSASKAAVILMTQALGLELAPYNITVNA 181 Query: 563 INPTVIMTEMAKVGWSD 613 I P + TEM + +++ Sbjct: 182 ICPGCMHTEMMEKSFAE 198 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 99.5 bits (237), Expect = 6e-20 Identities = 68/203 (33%), Positives = 102/203 (50%), Gaps = 9/203 (4%) Frame = +2 Query: 32 KMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS--IDIV 205 K + + GK ++T L GA +V SR + + + E+ +D + Sbjct: 4 KDQFNLSGKVAVITGSSKGIGKAIAKGLAEQGAQVVISSRNQEACDEVAKEFKEQGLDTI 63 Query: 206 DV--DIGDWEKTR----KVVESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKA 364 + IG ++ + K +ES G D LVNNAA+ V P + SP FDK DVNVKA Sbjct: 64 GIACHIGKEDQRKNLVDKTIESFGRIDILVNNAAINPVFGPIEEVSPEIFDKIMDVNVKA 123 Query: 365 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 544 ++S +V NK +G+I+NI+S + IYS SKAA+ LT+ A E G Y Sbjct: 124 PWSLSNLVLPHFQTNK-NGSIINIASVEALTPGLGLGIYSTSKAAILMLTKNQAKEWGKY 182 Query: 545 GIRVNAINPTVIMTEMAKVGWSD 613 G++ NAI P +I T+ + W + Sbjct: 183 GVKANAICPGLIKTKFSAALWQN 205 >UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=14; Clostridia|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Clostridium tetani Length = 249 Score = 99.1 bits (236), Expect = 8e-20 Identities = 64/191 (33%), Positives = 94/191 (49%), Gaps = 11/191 (5%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID-------IVDV 211 GK L+T EL GA ++ R L+ + +I+ I+ Sbjct: 8 GKVALITGASRGIGRGIAIELADKGACVIV--NYRKDLKGAEETKKTIEERGGYCRIIKC 65 Query: 212 DIGDWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ +E T+ K++ G D L+NNA ++ F+D ++D + N+K V N S Sbjct: 66 DVSSYEDTKLMIEKIIRDFGKIDILINNAGISKIGLFIDMEEEDWDNIINTNLKGVFNCS 125 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + V MI K +G I+NISS IYSASK +D+ T+A+A E+GP IRVN Sbjct: 126 RNVLPYMIGEK-NGVIINISSMWGSVGASCEVIYSASKGGVDSFTKALAKEVGPSNIRVN 184 Query: 560 AINPTVIMTEM 592 AI+P VI T M Sbjct: 185 AISPGVINTSM 195 >UniRef50_A1UGS1 Cluster: Short-chain dehydrogenase/reductase SDR; n=32; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 256 Score = 99.1 bits (236), Expect = 8e-20 Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 5/199 (2%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRT----RSHLESLQSEYPSIDI 202 ++ S GK LVT GA + ++H +L +E Sbjct: 10 LDFSLTGKVALVTGGASGIGAAIASAFAAKGARVAVADLNEPGAQAHAAALATESSGFRC 69 Query: 203 VDVDIGDWEKTRKVVE-SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D T V + G D LVN+A VA P D + ++++ T D+N+K + Sbjct: 70 DVSDPASVAATVDAVAGTFGRIDILVNSAGVARLAPAEDLTLTDWESTIDINLKGTFLMC 129 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 Q V R+M+ + G+IVN++SQA+ AL H Y ASK + +++ +A E G GIRVN Sbjct: 130 QAVGRRMLADGG-GSIVNLASQAASVALDQHVAYCASKFGVVGVSKVLAAEWGGRGIRVN 188 Query: 560 AINPTVIMTEMAKVGWSDP 616 I+PTV++TE+ W P Sbjct: 189 TISPTVVLTELGHKAWDGP 207 >UniRef50_A6SY22 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=41; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 272 Score = 98.3 bits (234), Expect = 1e-19 Identities = 62/199 (31%), Positives = 100/199 (50%), Gaps = 13/199 (6%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDI 202 +E++F+GK LVT L AGA ++ SR L+ L++E + + Sbjct: 17 IEVNFEGKVALVTGASSGLGARFAKVLAMAGAQVILASRRVDRLKELRAEIEAEGGAAQV 76 Query: 203 VDVDIGDWEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 V +D+ D+ + + G D LVNN+ V+ + +D +P ++ D N + Sbjct: 77 VSLDVTDYASIKSAIAHAETETGAIDILVNNSGVSASQRLVDVTPEDYAHMMDTNQRGAF 136 Query: 371 NISQVVARKMI-----ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALEL 535 ++Q VA++MI + K I+NI S A + + +Y SKAA+ +T+AMA+E Sbjct: 137 FVAQEVAKRMIARHKGDPKKQHRIINIGSVAGLRVVPELGLYCMSKAAVVHMTKAMAVEW 196 Query: 536 GPYGIRVNAINPTVIMTEM 592 G +GI NAI P I TEM Sbjct: 197 GKFGINTNAICPGYIGTEM 215 >UniRef50_A1AZ92 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Paracoccus denitrificans (strain Pd 1222) Length = 254 Score = 98.3 bits (234), Expect = 1e-19 Identities = 63/178 (35%), Positives = 87/178 (48%), Gaps = 5/178 (2%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 232 G+ ++VT AGA + +++E+P I + DI ++ Sbjct: 3 GQSVIVTAGASGIGLAIARSFLEAGARVAICDLNAEAFAQVKAEHPDIQTLQADIAREDQ 62 Query: 233 T----RKVVESLGHFDALVNNAAVA-VCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 +VV G D LVNNA +A C P D S +++ ++FDVNV V + + V Sbjct: 63 AIASVAEVVRLHGRVDVLVNNAGIAGACAPIADISAADWIRSFDVNVHGVFFMLRAVLPD 122 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 M T GAI+NIS+ + Y ASK AL+ LTRA A ELGP GIRVNAI P Sbjct: 123 MTARGT-GAIINISTGSVFTLPAGRADYVASKWALEGLTRAAAKELGPLGIRVNAIRP 179 >UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Burkholderia|Rep: Short-chain dehydrogenase/reductase SDR precursor - Burkholderia phytofirmans PsJN Length = 255 Score = 97.9 bits (233), Expect = 2e-19 Identities = 66/202 (32%), Positives = 102/202 (50%), Gaps = 15/202 (7%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIV-----ALSRTRSHLESLQSEYPSID 199 M + KGK LVT L R GA+++ + R + ++ ++ + Sbjct: 1 MTQALKGKLALVTGASRGIGAAIAARLARDGASVIVHYASSTERAEAVVKEIRDAGGEAE 60 Query: 200 IVDVDIGDWEKTRKVVESL---------GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDV 352 V ++ E R +++SL G D LVNNA PFLD S S++D F++ Sbjct: 61 TVGANLSKPEGVRSLIDSLSGAFGGRFEGRLDILVNNAGTVEYGPFLDSSESSYDTHFNL 120 Query: 353 NVKAVLNISQVVARKMIENKTHGAIVNISSQASKAA-LKDHTIYSASKAALDALTRAMAL 529 NV+A + +++ A +M+ G I+N+ S +AA L T+Y ASK AL TR ++ Sbjct: 121 NVRAPIKLAKDAAARMVA-AGWGRIINVGSAFGEAAPLPGVTLYIASKFALRGFTRGLSR 179 Query: 530 ELGPYGIRVNAINPTVIMTEMA 595 ELG YG+ VNA+ P I TE+A Sbjct: 180 ELGKYGVTVNAVQPGPIDTELA 201 >UniRef50_A0VRR7 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL 12 Length = 303 Score = 96.3 bits (229), Expect = 6e-19 Identities = 61/189 (32%), Positives = 95/189 (50%), Gaps = 4/189 (2%) Frame = +2 Query: 32 KMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD- 208 K +GKR L+T L +AGA ++ +R LE++ + IV Sbjct: 56 KRLFGLEGKRALITGASSGIGAHLALTLGQAGAEVILAARRADRLEAVAETLRAEGIVAQ 115 Query: 209 ---VDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 +D+ D V ++G D L+NN+ V+ + +D + +++D+ D N+K +S Sbjct: 116 TAALDVTDAASVAAAVTTVGPLDILINNSGVSGQDMVIDTTEADWDRVLDTNLKGAWRVS 175 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + A +I + G I+N++S LK Y+ASKA L LTRAMALEL G+RVN Sbjct: 176 RAFAPGLIARQ--GTILNVASILGIGVLKTVGPYAASKAGLIQLTRAMALELARDGVRVN 233 Query: 560 AINPTVIMT 586 A+ P I T Sbjct: 234 ALAPGYIET 242 >UniRef50_A0QZ64 Cluster: Acetoacetyl-CoA reductase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Acetoacetyl-CoA reductase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 187 Score = 96.3 bits (229), Expect = 6e-19 Identities = 47/130 (36%), Positives = 78/130 (60%) Frame = +2 Query: 236 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 RK+ LG D LVNNAAVA+ P + + +++D T N++ V ++ R M++ + Sbjct: 12 RKIDAELGSVDVLVNNAAVALLAPATEYTTTDWDTTMATNLRGVFLCTREFGRGMVD-RG 70 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA 595 G +VNI+SQ + + H YSA+KA + ++R +A E GP+G+ VN +PT++ T M+ Sbjct: 71 WGRVVNIASQNAIQGIGGHVAYSAAKAGILGMSRVLAAEWGPHGVTVNCASPTLVDTPMS 130 Query: 596 KVGWSDPIKA 625 + W D +A Sbjct: 131 RATWPDAARA 140 >UniRef50_A0T544 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia ambifaria MC40-6 Length = 271 Score = 95.9 bits (228), Expect = 7e-19 Identities = 63/200 (31%), Positives = 103/200 (51%), Gaps = 2/200 (1%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSE--YPSIDIVDVDIG 220 F G+ +LV+ R GA+ +A + + L++L++E + +D+ Sbjct: 33 FAGRHVLVSGATSGIGLAIARAFHRLGAHTIATGSSATKLDALRNEASLTGLRFAALDVR 92 Query: 221 DWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 + + SLG D LVN A VA P + + F DVN+++V+ +SQ AR + Sbjct: 93 NHGEIDAFFGSLGRLDVLVNAAGVA--RPRDEYADDVFGDVLDVNLRSVMRLSQA-ARPL 149 Query: 401 IENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVI 580 +E ++ G+IVNI+S S A D Y ASK + LTR++A E GP +RVNAI P Sbjct: 150 LE-QSRGSIVNIASMLSYLADADVPAYCASKTGVVGLTRSLAHEYGPRRVRVNAIAPGYH 208 Query: 581 MTEMAKVGWSDPIKANEMLS 640 T+M ++ W + +++S Sbjct: 209 RTDMTRIFWESEELSRKIVS 228 >UniRef50_Q1VP55 Cluster: Short chain dehydrogenase; n=4; Bacteria|Rep: Short chain dehydrogenase - Psychroflexus torquis ATCC 700755 Length = 255 Score = 95.5 bits (227), Expect = 1e-18 Identities = 56/191 (29%), Positives = 93/191 (48%), Gaps = 8/191 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI----VDV 211 + K K +VT L AGANI+ +SRT+ L+ + + Sbjct: 7 NLKNKTAVVTGAGKGLGRACAIALAEAGANIIIISRTKKDLDEVSKKIKKTKSKCKSYVC 66 Query: 212 DIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 DI ++++ + ++ D L+NNA + E F + + +N A N++Q+ A Sbjct: 67 DITNYDQIKNIINKQSKIDILINNAGNNIPEHFTKVKTKDMEYLVKINTMATFNLAQLCA 126 Query: 392 RKMIE----NKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 KMI+ K GAIVN+SSQ ++Y+ +K L+ LT+ M+++L Y IRVN Sbjct: 127 LKMIKLKKRKKIGGAIVNMSSQMGHVGGPIRSVYNMTKFGLEGLTKGMSIDLAKYNIRVN 186 Query: 560 AINPTVIMTEM 592 + PT ++T M Sbjct: 187 TVCPTFVVTPM 197 >UniRef50_A2W1T9 Cluster: Short-chain dehydrogenase/reductase SDR; n=24; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cenocepacia PC184 Length = 288 Score = 95.5 bits (227), Expect = 1e-18 Identities = 61/191 (31%), Positives = 101/191 (52%), Gaps = 9/191 (4%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDW 226 F GK++LV ++ ++G ++V + E++++E + V V + Sbjct: 36 FSGKKLLVVGGTSGIGLATAKQVLKSGGSVVLTGNRKDKAEAVRAELSGLGPVSVIAANL 95 Query: 227 --EKTRKVVES---LGHFDA--LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 E+ + + H D LVN+A + V + F+D S++D +N +A I+Q Sbjct: 96 MTEEGMNAIRAEINANHKDISLLVNSAGIFVPKAFIDHEESDYDMYLSLN-RATFFITQD 154 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDH--TIYSASKAALDALTRAMALELGPYGIRVN 559 V R M+ K GAIVN+ S ++AAL D + YS +KA L ALTR +A+EL GIRVN Sbjct: 155 VVRNMLAAKRQGAIVNVGSIGAQAALGDSAASAYSMAKAGLHALTRNLAIELADAGIRVN 214 Query: 560 AINPTVIMTEM 592 A++P ++ T + Sbjct: 215 AVSPAIVQTSI 225 >UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 248 Score = 95.5 bits (227), Expect = 1e-18 Identities = 67/202 (33%), Positives = 99/202 (49%), Gaps = 9/202 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESL--------QSEYPSID 199 + GK +VT L R GA +VA T E Q +D Sbjct: 3 NLSGKVAIVTGAGQGIGRGIALRLARDGAIVVATDITGKENEVAEEVRKLGGQGMALRLD 62 Query: 200 IVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 + D + + E R V + GH D LVNNA + +PF++ + +++ + +VN+ V N++ Sbjct: 63 VTDGKMAE-EVARTVFDKYGHIDILVNNAGIYPFKPFMEMTFNDWYRVINVNLNGVFNVT 121 Query: 380 QVVARKMIENKTHGAIVNISSQASKA-ALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 + V M++ K +G I+NI+S A T YSASKA + TRA+ALEL YGI V Sbjct: 122 RAVVPYMVKQK-NGRIINIASIAGAVMGFMGLTHYSASKAGIVGFTRALALELARYGITV 180 Query: 557 NAINPTVIMTEMAKVGWSDPIK 622 NAI P I T A G + ++ Sbjct: 181 NAIAPGAINTPGAATGSEEQVR 202 >UniRef50_P33368 Cluster: Uncharacterized oxidoreductase yohF; n=21; Enterobacteriaceae|Rep: Uncharacterized oxidoreductase yohF - Escherichia coli (strain K12) Length = 253 Score = 95.5 bits (227), Expect = 1e-18 Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 4/143 (2%) Frame = +2 Query: 197 DIVDVDIGDWEK----TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 364 +IV +D+G+ + K+++ LG D LVNNA PFLD + + K F V+V Sbjct: 55 EIVQLDLGNLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDG 114 Query: 365 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 544 SQ+ AR+M++ G I+NI+S L D + Y+A+K AL LT+AMALEL + Sbjct: 115 AFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRH 174 Query: 545 GIRVNAINPTVIMTEMAKVGWSD 613 I VNA+ P I T M + SD Sbjct: 175 KILVNAVAPGAIATPMNGMDDSD 197 >UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chain dehydrogenase; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to short-chain dehydrogenase - Strongylocentrotus purpuratus Length = 250 Score = 95.1 bits (226), Expect = 1e-18 Identities = 50/126 (39%), Positives = 77/126 (61%), Gaps = 1/126 (0%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 K +E G D L+NNA F D + FD +N+++ + +S++ + E+K Sbjct: 76 KTIEKFGRLDILINNAGRPAKGRFHDLQMTFFDDVMRLNLRSAIYLSKLAIPYLKESK-- 133 Query: 419 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 G +VN+SS ASK + YS SK ALD T+++A+ELGPYG+RVN++NP VI+T + + Sbjct: 134 GCVVNMSSVASKTTCDYNPTYSISKVALDQFTKSLAVELGPYGVRVNSLNPGVILTPLYR 193 Query: 599 -VGWSD 613 +G SD Sbjct: 194 NLGKSD 199 >UniRef50_Q3BBM8 Cluster: Xylitol dehydrogenase; n=1; Pantoea ananatis|Rep: Xylitol dehydrogenase - Pantoea ananas (Erwinia uredovora) Length = 264 Score = 95.1 bits (226), Expect = 1e-18 Identities = 46/131 (35%), Positives = 74/131 (56%) Frame = +2 Query: 242 VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHG 421 +V+ GH D LVN A + +P L+ + + K VN+ SQ ++M++ G Sbjct: 91 IVDHYGHIDILVNCAGYVMLQPVLETDFAEWQKQIAVNLTGPFLCSQAAGKQMVKAGNGG 150 Query: 422 AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKV 601 I+NI+SQA+ A+ +H Y+++KA L +T+ MA E P+ I VN ++PTV++T M + Sbjct: 151 KIINIASQAASIAIDNHVAYTSAKAGLLGMTKVMAKEFAPHRINVNTLSPTVVLTPMGEK 210 Query: 602 GWSDPIKANEM 634 W K EM Sbjct: 211 AWRGE-KGTEM 220 >UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain dehydrogenase/reductase family; n=1; Coxiella burnetii Dugway 7E9-12|Rep: oxidoreductase, short chain dehydrogenase/reductase family - Coxiella burnetii Dugway 7E9-12 Length = 258 Score = 94.7 bits (225), Expect = 2e-18 Identities = 60/201 (29%), Positives = 108/201 (53%), Gaps = 9/201 (4%) Frame = +2 Query: 38 EISFKGKRILVTXXXXXXXXXXXXELWRAGANIVAL----SRTRSHLESLQSEYPS-IDI 202 + S K K ++VT + + G+ +V + + +E+ S+YP+ + + Sbjct: 3 DYSVKDKVVIVTGATKGMGLASSKQFLKMGSKVVMVYFGDAENARKVEAALSDYPAQLLL 62 Query: 203 VDVDIGDWEKTRKVV-ESLGHF---DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 + DI E ++++ E++ F + LVNNA + FL + +F++ DVN+KA + Sbjct: 63 IKADITKAEDRQRIIDETINTFQRINVLVNNAGIPAKAGFLKEAEEDFNRVIDVNLKAPI 122 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 ++++VA +MI+ G+I+N SS A A+ + Y A+KA + ++ MA LG YGI Sbjct: 123 FLAKLVAEQMIKQAQGGSIINFSSVAGHRAMGGIS-YDAAKAGIIRASQTMANTLGKYGI 181 Query: 551 RVNAINPTVIMTEMAKVGWSD 613 RVN+I+P TEM + W + Sbjct: 182 RVNSISPGTHKTEMNRYQWEN 202 >UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 263 Score = 94.7 bits (225), Expect = 2e-18 Identities = 63/191 (32%), Positives = 93/191 (48%), Gaps = 5/191 (2%) Frame = +2 Query: 29 LKMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD 208 +K F+ + ++VT GA +V S E SE + V Sbjct: 1 MKTHKRFERQVVVVTGAGHGIGRAVALRFADEGALVVLNDLDASRAEDAASEVKADLWVA 60 Query: 209 VDIGDWEKTR----KVVESLGHFDALVNNAA-VAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 D+ D E+ +V E G D LVNNA + FL+ +D+ VN+K Sbjct: 61 ADVSDKEQVDAMFDRVEEEYGRIDVLVNNAGNIYAARHFLEGDEQWWDQVLGVNLKGAFL 120 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 S A+KM+ ++ G I+N+SS + A + + Y ASK ++A+TRAMAL+L PYG+R Sbjct: 121 CSHRAAQKMVRQRS-GVILNMSSGGATRAHRGNVAYDASKGGIEAMTRAMALDLAPYGVR 179 Query: 554 VNAINPTVIMT 586 VNAI P +I T Sbjct: 180 VNAIVPGLIRT 190 >UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p - Drosophila melanogaster (Fruit fly) Length = 255 Score = 94.7 bits (225), Expect = 2e-18 Identities = 57/188 (30%), Positives = 91/188 (48%), Gaps = 4/188 (2%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVD 208 +S K ++VT L R GA + + R ++LE SL+ I + D Sbjct: 5 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVAD 64 Query: 209 VDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 V ++ + G D LVNNA + +D FD + N++ V+ +++ V Sbjct: 65 VTKDADAIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTKAV 124 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 ++ KT GA+VN+SS A Y SKAALD T+ +ALE+ P G+RVN++N Sbjct: 125 LPHLL--KTKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVN 182 Query: 569 PTVIMTEM 592 P ++T + Sbjct: 183 PGFVVTNI 190 >UniRef50_A1R350 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Arthrobacter aurescens TC1|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Arthrobacter aurescens (strain TC1) Length = 264 Score = 94.3 bits (224), Expect = 2e-18 Identities = 61/192 (31%), Positives = 99/192 (51%), Gaps = 6/192 (3%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI---V 205 M +F GK +L+T + GAN+V +SR + + S S + Sbjct: 1 MNRTFSGKTVLITGASQGIGLAAAEHFLKEGANVVGVSREPADMASTTSTNADHFLHISA 60 Query: 206 DVDIGDWEKT--RKVVESLGHFDALVNNA-AVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 D+ + T R+ ++ G D LVNNA AVAV + FLD + ++ T ++N + + Sbjct: 61 DLSLPGTPGTAVRQALQRFGGIDVLVNNAGAVAVRKGFLDATDEMWESTMELNFMGYVRM 120 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 S+ V M+E + G+I+++ S+A + L D YS SKAA+ +L++ ++ E GP GIR Sbjct: 121 SREVLPHMLEAGS-GSIIHVGSEAGRTPLVDAPDYSVSKAAILSLSKLLSREFGPKGIRS 179 Query: 557 NAINPTVIMTEM 592 N + P I T M Sbjct: 180 NVVAPAHIYTPM 191 >UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 245 Score = 93.9 bits (223), Expect = 3e-18 Identities = 62/193 (32%), Positives = 102/193 (52%), Gaps = 10/193 (5%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQ------SEYPSIDIVDVD 214 GK +VT EL + GA+ VA+ S+ ++++ + +I D Sbjct: 4 GKVAIVTGGAGDIGRRICIELAKEGAS-VAIHYNSSYEKAVELRDYIRENFSYAEIFQAD 62 Query: 215 IGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 I + ++ ++++ + G D L+NNA +A +PF++ + ++D+ +VN+K + N +Q Sbjct: 63 ISNRKQVDEMIDEIYRKFGRIDYLINNAGIAQIKPFVEITEEDWDRMMNVNLKGLFNCTQ 122 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 V R M+ K G+I+NISS + YSASK + A T+A+A ELGP IRVN Sbjct: 123 SVLRYMLPKK-QGSIINISSIWGISGASCEVHYSASKGGVIAFTKALAKELGPSKIRVNC 181 Query: 563 INPTVIMTEMAKV 601 I P VI T M + Sbjct: 182 IAPGVIDTRMNNI 194 >UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 254 Score = 93.9 bits (223), Expect = 3e-18 Identities = 64/207 (30%), Positives = 101/207 (48%), Gaps = 8/207 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID------IV 205 + +GK +VT L +AGA++V SRT++ L+++ E ++ Sbjct: 7 NLEGKVAIVTGGSRGFGKAIALGLAQAGADVVVASRTQADLDAVAEEIRALGRKSLAVAT 66 Query: 206 DV-DIGDWEK-TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ D G E K +E+ G D LVNNA PFL + +D+ DVN+K + Sbjct: 67 DMLDRGSIENLAAKTMEAFGKIDILVNNAGQGWTVPFLKWTDEQWDQILDVNLKGYFLCT 126 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 Q+V + M + K G ++NISS L Y+ASK ++A+T+ +A E GI VN Sbjct: 127 QIVGQHMFKAKA-GRVINISSAMGSYPLPYMVPYAASKGGINAMTKCLAQEWATRGITVN 185 Query: 560 AINPTVIMTEMAKVGWSDPIKANEMLS 640 AI P+ T++ K D ++S Sbjct: 186 AIAPSYFSTDINKDAMEDEATTKLIMS 212 >UniRef50_Q8RL53 Cluster: MupS; n=1; Pseudomonas fluorescens|Rep: MupS - Pseudomonas fluorescens Length = 257 Score = 93.9 bits (223), Expect = 3e-18 Identities = 56/163 (34%), Positives = 88/163 (53%), Gaps = 4/163 (2%) Frame = +2 Query: 122 AGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK----TRKVVESLGHFDALVNNAA 289 AG N+ SR S + SE +D D+ ++V + G D LVNNAA Sbjct: 44 AGYNVATFSRRESPAVTELSERADFHWQALDCTDYSALTAFVQQVEKRFGGLDGLVNNAA 103 Query: 290 VAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKD 469 V ++ D D+N+K L ++++V K+++ G++VN+SS + Sbjct: 104 TGVEGILSTMRVADIDSALDINLKGQLYLTKLVTAKLLKRGA-GSVVNVSSINALRGHSG 162 Query: 470 HTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 T+YSA+KAA+D LTR++A ELGP GIRVN+++P ++M K Sbjct: 163 LTVYSATKAAMDGLTRSLAKELGPRGIRVNSVSPGYFSSDMVK 205 >UniRef50_Q2AZB5 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacillus cereus group|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus weihenstephanensis KBAB4 Length = 248 Score = 93.9 bits (223), Expect = 3e-18 Identities = 63/205 (30%), Positives = 98/205 (47%), Gaps = 9/205 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWE 229 K K I+++ N++AL + L + S +V +D+ + Sbjct: 3 KNKTIMISGANSGIGNACIEYFLEKSFNVIALDINTNKLVDYTKTHTSFKLVQIDLSNSN 62 Query: 230 KTRKVVESLGHF----DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 + + L D L+N A + P L+ S F K DVN+ A +S+ A++ Sbjct: 63 EINNLFIQLDTDTLCPDILINAAGIREITPVLELSDDLFKKVIDVNLVAPFILSREAAKR 122 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 ++KT G IVNI+S + A + Y ASK AL LT+ MA+E G IRVN+I+P V Sbjct: 123 WYKSKTKGCIVNIASVSGLMAEPERAAYVASKHALIGLTKQMAMEFGKQNIRVNSISPGV 182 Query: 578 IMTEMAKVGWSDP-----IKANEML 637 I TE+ + +SD IK+N+ L Sbjct: 183 IRTELTEEYFSDERLVSLIKSNQSL 207 >UniRef50_Q08Z99 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Stigmatella aurantiaca DW4/3-1 Length = 252 Score = 93.9 bits (223), Expect = 3e-18 Identities = 57/185 (30%), Positives = 94/185 (50%), Gaps = 4/185 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGD 223 SF G LV+ L + GA + L+ + S L S + +P++ + D+ Sbjct: 6 SFDGSVFLVSGASSGIGEAAAVALRQRGAAVYGLTSSSSTLASARERHPAVRWLSADVTR 65 Query: 224 WEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 + V ++ G D LVN A + P + F+VNV + ++Q Sbjct: 66 RSEVGTAVAAILAEAGRLDGLVNTAGIYTFAPLEASGEEMMRRQFEVNVFGTVFLTQASL 125 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 + ++K G IVN+SS ++ A+ D +IY+A+K A+++LTRA ALEL +G+RVNAI+P Sbjct: 126 AALKDSK--GTIVNVSSTSAHKAMADQSIYAATKGAVESLTRAWALELARHGVRVNAISP 183 Query: 572 TVIMT 586 +T Sbjct: 184 GPTLT 188 >UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella sediminis HAW-EB3|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sediminis HAW-EB3 Length = 245 Score = 93.9 bits (223), Expect = 3e-18 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 5/189 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSE-----YPSIDIVD 208 +F+ K +L+T GA +V R +S LE E YP + V Sbjct: 3 NFENKVVLITGGGTGIGKATASAFIAKGATVVITGRRQSVLEETSQELGPQVYPIVGDVS 62 Query: 209 VDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 G + + G D LVNNA P + S + + + NV A+L + + Sbjct: 63 KKGGPARIVEETISKFGRLDVLVNNAGTGKMGPLSETSDEDIESIYRTNVFALLALVREA 122 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 + +K GA+VNISS A++ + Y++SKAA++ TR +A ELGP GIRVNA+ Sbjct: 123 TVHLANSK--GAVVNISSVAAQGMMPAVAAYASSKAAVEHATRLLAAELGPMGIRVNAVA 180 Query: 569 PTVIMTEMA 595 P + T++A Sbjct: 181 PGLTNTDIA 189 >UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC79752 protein - Strongylocentrotus purpuratus Length = 303 Score = 93.5 bits (222), Expect = 4e-18 Identities = 63/172 (36%), Positives = 86/172 (50%), Gaps = 3/172 (1%) Frame = +2 Query: 122 AGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK--TRKVVESLGHFDALVNNAAVA 295 AG L RT+ +E ++ G + K + +E G D LVNNA V Sbjct: 82 AGRKEANLMRTKDSCMQTGNEEALTVTGELRDGSYRKHLVEQAMEEYGKLDILVNNAGVI 141 Query: 296 VCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHT 475 + S ++D DVNV++V +++ + +IE K G IVN+SS A Sbjct: 142 SLGSIENSSLEDYDTMMDVNVRSVFHLTSLAVPHLIETK--GNIVNVSSVNGLRAFAGVL 199 Query: 476 IYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK-VGWSDPIKAN 628 Y SKAALD TR ALEL P G+RVN++NP V +TE+ K G SD AN Sbjct: 200 SYCMSKAALDHFTRCTALELAPKGVRVNSVNPGVTITELQKRGGLSDEAYAN 251 >UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola batsensis HTCC2597|Rep: Probable dehydrogenase - Oceanicola batsensis HTCC2597 Length = 254 Score = 93.5 bits (222), Expect = 4e-18 Identities = 67/201 (33%), Positives = 98/201 (48%), Gaps = 9/201 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHL----ESLQSEYPSIDIVD 208 + K K +++T AGA +V SR R E+++ + +V Sbjct: 5 LRLKDKVVVITGSSRGIGRAMAEMFAEAGARVVVSSRKREACKPVAEAIREKGGEAIVVP 64 Query: 209 VDIGDWEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLN 373 IG+ E + +V++ G D LV NAA+ V P D + FDK NV+ + Sbjct: 65 CHIGNPEDLQNLVDTTIREWGRIDVLVPNAAINPVYGPMQDLDDAVFDKMLVTNVRTINT 124 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 + ++V +M EN GA+V ISS A+ Y +KAA A+ RA+ALE GP IR Sbjct: 125 MCKMVLPRMAENGG-GAVVIISSVAAIKGSTTLGAYGVTKAADAAVARALALEWGPQNIR 183 Query: 554 VNAINPTVIMTEMAKVGWSDP 616 VNAI P +I T+ A+ W DP Sbjct: 184 VNAIGPGLIKTDFARALWEDP 204 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 93.1 bits (221), Expect = 5e-18 Identities = 63/195 (32%), Positives = 100/195 (51%), Gaps = 8/195 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANI----VALSRTRSHLESLQSEYPSIDIVD 208 ++F+GK +L+T GA + ++ + + +E ++S + Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60 Query: 209 VDIG-DWEK-TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 D+ D E+ +K VE+ G D LVNNA + + S +FDKT VNVK +S+ Sbjct: 61 GDVAKDAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLLSK 120 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 +M + + G IVN+SS+A + +YS SKAAL LTR++A++ YGIRVNA Sbjct: 121 YAVEQM-KKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVNA 179 Query: 563 INPTVIMTE--MAKV 601 + P +E MA+V Sbjct: 180 VCPGTTQSEGLMARV 194 >UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Flavobacteriaceae|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leeuwenhoekiella blandensis MED217 Length = 246 Score = 92.7 bits (220), Expect = 7e-18 Identities = 56/148 (37%), Positives = 85/148 (57%), Gaps = 5/148 (3%) Frame = +2 Query: 212 DIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ + E K+++ L G D LVNNA + + + F + + + FD+ NVK+V IS Sbjct: 57 DLNNLEAIPKLIDELLQATGKIDVLVNNAGINMKKDFAEVTDAEFDRILHTNVKSVFAIS 116 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + V + M N G+IVNISS A++ + Y+ASK A++ +TRAMA++L Y IRVN Sbjct: 117 REVVKSMKGNYG-GSIVNISSMAAQYGIPQVIAYTASKTAIEGMTRAMAVDLAQYNIRVN 175 Query: 560 AINPTVIMTEM-AKVGWSDPIKANEMLS 640 + P I T M AK SD + + + S Sbjct: 176 CVAPGFIKTPMTAKALNSDKQRKDRVFS 203 >UniRef50_Q11C87 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 247 Score = 92.3 bits (219), Expect = 9e-18 Identities = 55/149 (36%), Positives = 81/149 (54%) Frame = +2 Query: 194 IDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 ID+ D + D RKV E D +VN A + PF + +P+ F K DVNV Sbjct: 57 IDVTDENAVD-AAVRKVAEPFERIDGVVNCAGIGQNIPFNETTPAQFRKVLDVNVIG--- 112 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 S +VA+ + + ++G++VNI+S + Y ASK A++ +TR MA+EL P+G+R Sbjct: 113 -SFIVAQSAVRHMSNGSVVNITSVSGIQGSVGRVAYGASKGAVNTMTRIMAVELAPHGVR 171 Query: 554 VNAINPTVIMTEMAKVGWSDPIKANEMLS 640 VNAI P + T MA+ W D N+ S Sbjct: 172 VNAIAPGPVETPMAQ-KWHDEKTRNDWKS 199 >UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4; Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase - Clostridium perfringens (strain SM101 / Type A) Length = 253 Score = 92.3 bits (219), Expect = 9e-18 Identities = 50/122 (40%), Positives = 74/122 (60%) Frame = +2 Query: 227 EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIE 406 E KV+E G D L+NNA V+ + S +F K D+NVKA+ N ++ V+ ++++ Sbjct: 78 EMVDKVLEKWGTIDILINNAGVSDNKSIYTQSDEDFSKIIDINVKAIFNCTKAVS-EIMK 136 Query: 407 NKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT 586 NK +G I+N SS S K Y SK A++ LT+++A ELG GIRVNA+ P +I T Sbjct: 137 NKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLARELGRDGIRVNAVAPGIIAT 196 Query: 587 EM 592 +M Sbjct: 197 DM 198 >UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseovarius sp. HTCC2601 Length = 255 Score = 92.3 bits (219), Expect = 9e-18 Identities = 63/197 (31%), Positives = 92/197 (46%), Gaps = 8/197 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVAL----SRTRSHLESLQSEYPSIDIVDVDI 217 +G+ +VT L GAN+VA+ + + L+ L + V VD+ Sbjct: 5 EGRTYIVTGAGSGIGAATVARLIEDGANVVAVDLDQAAAQKTLDGLGLDASRAVAVGVDV 64 Query: 218 GDWEK----TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 D +K T + + G D +VN A V LD +D +VN++ N SQ Sbjct: 65 SDEDKVDAMTAEGIAKFGGLDGVVNCAGVRGVGNILDTDHGVWDLNMNVNIEGSFNTSQA 124 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 R E+ G+IVNISSQA A+ + Y SK + LTR +A+E+ P+GIR N I Sbjct: 125 FCRYAREHNRPGSIVNISSQAGVEAVPNRLSYVTSKHGVVGLTRGVAIEMAPHGIRCNGI 184 Query: 566 NPTVIMTEMAKVGWSDP 616 P +I T M +DP Sbjct: 185 APGMIATAMTAGMRADP 201 >UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Pasteurellaceae|Rep: Short-chain dehydrogenase/reductase SDR - Actinobacillus succinogenes 130Z Length = 248 Score = 92.3 bits (219), Expect = 9e-18 Identities = 58/175 (33%), Positives = 92/175 (52%), Gaps = 4/175 (2%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKT 235 K LVT + + GAN+V + R + LE ++ +I + D+ E Sbjct: 7 KTALVTGGGTGIGRAIAKRMAKDGANVVIIGRNEATLEESAEQHENITYLVADVLKSEDI 66 Query: 236 RKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 403 +V+ E G D +VNNA +A P + + ++FD+TF +NV+AV++++ + Sbjct: 67 ARVLTEIQEEFGKLDIVVNNAGIAPMTPIENINLADFDRTFALNVRAVIDVTAQAIPYLK 126 Query: 404 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 +K G IVNI S + + IY+ASKAA+ +LTR A EL YGIRVN ++ Sbjct: 127 ASK--GNIVNIISGLVHNPMPGNCIYTASKAAVLSLTRTWAKELAAYGIRVNCVS 179 >UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=4; Bacillaceae|Rep: Uncharacterized oxidoreductase yoxD - Bacillus subtilis Length = 238 Score = 92.3 bits (219), Expect = 9e-18 Identities = 57/192 (29%), Positives = 98/192 (51%), Gaps = 8/192 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI----VDV 211 S + K L+T L + G NI + RT +++E + E ++ + Sbjct: 3 SLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEVKALGVKAAFAAA 62 Query: 212 DIGDWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ D ++ + V E LG D L+NNA ++ FLD S ++ VN+ V +++ Sbjct: 63 DVKDADQVNQAVAQVKEQLGDIDILINNAGISKFGGFLDLSADEWENIIQVNLMGVYHVT 122 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + V +MIE K G I+NISS A + + YSASK A+ LT ++ E+ + IRV+ Sbjct: 123 RAVLPEMIERKA-GDIINISSTAGQRGAAVTSAYSASKFAVLGLTESLMQEVRKHNIRVS 181 Query: 560 AINPTVIMTEMA 595 A+ P+ + ++M+ Sbjct: 182 ALTPSTVASDMS 193 >UniRef50_Q0FYP0 Cluster: Putative oxidoreductase protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative oxidoreductase protein - Fulvimarina pelagi HTCC2506 Length = 243 Score = 91.9 bits (218), Expect = 1e-17 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 3/137 (2%) Frame = +2 Query: 209 VDIGDWEKTRKVVESLGH---FDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 +D+ D VE++G D LVNNA + + P +D+T +N++A + Sbjct: 57 IDLQDPGAIASGVEAIGKDSGIDILVNNAGLGMVFPAEKTDIDAWDRTMRINLRAPW-LM 115 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 A ++ G IVN+SSQA A+++H Y ASKA L LT+ MA+E YGI N Sbjct: 116 AAAALPFLKASGRGRIVNLSSQAGVIAIEEHAAYGASKAGLINLTQVMAIEWAQYGITAN 175 Query: 560 AINPTVIMTEMAKVGWS 610 AI PTV+ T MA VGWS Sbjct: 176 AIAPTVVETPMALVGWS 192 >UniRef50_A1UP20 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=7; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 244 Score = 91.9 bits (218), Expect = 1e-17 Identities = 58/170 (34%), Positives = 81/170 (47%), Gaps = 1/170 (0%) Frame = +2 Query: 65 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-SIDIVDVDIGDWEKTRK 241 LVT L GA +V R +E ++ V D+ D + + Sbjct: 9 LVTGGTSGIGLASARLLAAEGAEVVVSGRDAERGAQAVAEIGGAVRFVQADMSDPQSVKD 68 Query: 242 VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHG 421 + E G D LVNNA V P LD ++F+ FD NV+ + VAR M+ + G Sbjct: 69 LAEQAGDVDILVNNAGVFPAAPTLDQDLASFETMFDTNVRGAYFLVAEVARGMVA-RGRG 127 Query: 422 AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 AIVNI+S A + Y A+KAAL +LTR A E G G+RVN+++P Sbjct: 128 AIVNITSPAGDKGFPGTSAYGATKAALASLTRTWAAEFGANGVRVNSVSP 177 >UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; Sarcoptes scabiei type suis|Rep: Putative uncharacterized protein - Sarcoptes scabiei type suis Length = 304 Score = 91.9 bits (218), Expect = 1e-17 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%) Frame = +2 Query: 29 LKMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSE-------- 184 LKM+ F GK LVT + + GA + R + LE + E Sbjct: 33 LKMKYDFSGKVALVTGSSSGIGAAIALQFAQYGAKVCITGRDSNALEKVAGEIEKATGGK 92 Query: 185 YPSIDIVDVDIGDWEKT----RKVVESLGHFDALVNNAAVAVCEPFL--DCSPSNFDKTF 346 + + I+ + D + + V G D LVNNA + L + ++DK F Sbjct: 93 HRPLKIIGGLVEDRQLPVRLINETVNEFGRLDFLVNNAGGSTAHGKLTDENLMDSYDKVF 152 Query: 347 DVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMA 526 D+NV++VL++ QV A+ +E KT G I+NISS A A + IYS SKAALD +T+ +A Sbjct: 153 DLNVRSVLHLCQV-AKPHLE-KTKGNIINISSIA--AIVPYSLIYSPSKAALDMMTKCLA 208 Query: 527 LELGPYGIRVNAINPTVIMT 586 +E G G+RVN+INP + T Sbjct: 209 IEYGDIGVRVNSINPGPVRT 228 >UniRef50_Q1YNT8 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; gamma proteobacterium HTCC2207|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - gamma proteobacterium HTCC2207 Length = 256 Score = 91.5 bits (217), Expect = 2e-17 Identities = 51/135 (37%), Positives = 79/135 (58%), Gaps = 4/135 (2%) Frame = +2 Query: 200 IVDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAV 367 +V +D+ D + + ++ LG D +V NA +PFL+ + +D +VN+K V Sbjct: 63 VVTMDVTDRDSVKAGFDAAEAQLGTPDIVVCNAGATGAQPFLEMEEAVWDNVLNVNLKGV 122 Query: 368 LNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 547 N+ Q A++M+ G+I+NISS + A+ K T YS+SKAAL+ LT M EL + Sbjct: 123 FNLGQEAAQRMVAAGKPGSIINISSICAVASFKGLTHYSSSKAALNQLTAVMGHELAEHS 182 Query: 548 IRVNAINPTVIMTEM 592 IRVNA+ P +MT+M Sbjct: 183 IRVNALAPGYMMTDM 197 >UniRef50_Q1IKU0 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 255 Score = 91.5 bits (217), Expect = 2e-17 Identities = 64/205 (31%), Positives = 94/205 (45%), Gaps = 9/205 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVA--LSR---TRSHLESLQSEYPSIDIVDVD 214 KGK L+T + GA++ LS +S +E ++S + + +D Sbjct: 4 KGKHALITGGDQGIGRGIALRFAQEGADVAIGFLSNDDHAKSAVEEMRSHGVNAAALQID 63 Query: 215 IGDWEKTRK----VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 + + K +LG D LVNNA + + FL + +FD VN+K +SQ Sbjct: 64 VSNIGALAKFYADATRALGPLDVLVNNAGIEKRDEFLKSTEDDFDSVIAVNLKGPYFLSQ 123 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 + AR + E K G I+NISS + + Y A+K L L R +A+EL PYGI VN Sbjct: 124 LFARDLAEAKRPGKIINISSVHEELPFPNFASYCAAKGGLKMLCRNLAIELAPYGITVNN 183 Query: 563 INPTVIMTEMAKVGWSDPIKANEML 637 I P I T + DP K +L Sbjct: 184 IAPGAIKTPINDKLLHDPSKLKPLL 208 >UniRef50_A4SZ40 Cluster: Short-chain dehydrogenase/reductase SDR; n=26; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polynucleobacter sp. QLW-P1DMWA-1 Length = 267 Score = 91.5 bits (217), Expect = 2e-17 Identities = 62/176 (35%), Positives = 88/176 (50%), Gaps = 6/176 (3%) Frame = +2 Query: 119 RAGANIVALSRTRSHLESLQSEYPSIDIVDV--DIGDWEKTRK----VVESLGHFDALVN 280 R G + L + L+ S D++ + D+ ++ K V+ GH DALVN Sbjct: 31 RHGYQVALLDIDKVTLDKTMQSIGSEDVIGIHCDVSKPQEVEKASQEVLAQFGHVDALVN 90 Query: 281 NAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAA 460 NA VAV +P L+ S + N+ SQV R +++N GAIVNI+S + A Sbjct: 91 NAGVAVFKPVLETSFDEWRTVLGTNLDGAFICSQVFGRSIVQNGG-GAIVNIASISGLRA 149 Query: 461 LKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKAN 628 Y SKAAL LT+ A+ELG +RVN I P + TEMAK+ S I+ + Sbjct: 150 STLRVAYGTSKAALIQLTKQYAVELGNLNVRVNVIAPGPVETEMAKLVHSVAIRTD 205 >UniRef50_Q26GY6 Cluster: Short-chain dehydrogenases/reductases family (SDR) protein; n=12; Bacteroidetes|Rep: Short-chain dehydrogenases/reductases family (SDR) protein - Flavobacteria bacterium BBFL7 Length = 256 Score = 91.1 bits (216), Expect = 2e-17 Identities = 60/190 (31%), Positives = 90/190 (47%), Gaps = 8/190 (4%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV---DIGDW 226 K +L+T L G IV R L L+ E ++ V+ D+ D Sbjct: 8 KTVLITGATSGIGLATAITLAENGFAIVLCGRNMEKLAELKEELSAVVPVETLAFDVRDK 67 Query: 227 EKTRKVVESL----GHFDALVNNAAVAV-CEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 + + SL D L+NNA A +P S ++D D+NVK +L +S + Sbjct: 68 DMVASQIASLKAPFNEIDILINNAGNAHGLDPIDRGSIDDWDAMMDINVKGLLYVSNAII 127 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 +M + K G I+NI S A K + +Y SK A+DA+T M L+L PY IRV A+NP Sbjct: 128 PQMRDRK-RGQIINIGSTAGKEVYPNGNVYCGSKHAVDAITTGMRLDLNPYNIRVGAVNP 186 Query: 572 TVIMTEMAKV 601 ++ T ++V Sbjct: 187 GLVETNFSEV 196 >UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 283 Score = 91.1 bits (216), Expect = 2e-17 Identities = 61/195 (31%), Positives = 101/195 (51%), Gaps = 11/195 (5%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQ---SEYPSI-DIVDV-- 211 KGK ++VT G+ +V +R+ ++++ ++Y S + + V Sbjct: 15 KGKVVIVTGSTRGIGYEIVKLFKEMGSRVVVNARSADEVQTVVKKLNDYVSDGEAIGVAG 74 Query: 212 DIGDWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ +E K+V + G D LVNNA + + L+ S ++++T +++ + +S Sbjct: 75 DVSKYEDCEKIVNETVDKYGKIDVLVNNAGINMIRDSLNLSIDDWERTLRIDLFSAFYMS 134 Query: 380 QVVARKMIENKTHGAIVNISSQASK-AALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 Q+VAR M+ K G+IVNI+S AL Y+A+KA L LTR +A+E P GIRV Sbjct: 135 QLVARTMVAKKVKGSIVNIASMVGPIVALPKRAAYAAAKAGLVGLTRVLAVEWAPLGIRV 194 Query: 557 NAINPTVIMTEMAKV 601 NAI P I + +V Sbjct: 195 NAIAPGYIWSSAQEV 209 >UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=2; Bacillus|Rep: Uncharacterized oxidoreductase yqjQ - Bacillus subtilis Length = 259 Score = 91.1 bits (216), Expect = 2e-17 Identities = 56/188 (29%), Positives = 92/188 (48%), Gaps = 5/188 (2%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVDVDI 217 GKRI +T GA+++ +R L ++ + +I +D+ Sbjct: 6 GKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEWSGQCEIFPLDV 65 Query: 218 GDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 G E +V + +G D L+NNA + E LD + + FDVNV ++ ++ V + Sbjct: 66 GRLEDIARVRDQIGSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLIACTKAVLPQ 125 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 M+E K G I+NI+SQA K A ++YSA+K A+ + A+ +EL GI V +NP Sbjct: 126 MLEQK-KGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMELSGTGIYVTTVNPGP 184 Query: 578 IMTEMAKV 601 I T+ + Sbjct: 185 IQTDFFSI 192 >UniRef50_Q8YJQ0 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE; n=6; Brucellaceae|Rep: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella melitensis Length = 254 Score = 90.6 bits (215), Expect = 3e-17 Identities = 45/108 (41%), Positives = 62/108 (57%) Frame = +2 Query: 266 DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQ 445 D LVNNA + P L+ S +D N+K +Q A++M+E GAIVNI S Sbjct: 83 DVLVNNAGIQTWAPLLELSEEGWDDVIRTNLKGCFLNTQAAAKRMVEADKGGAIVNIGSG 142 Query: 446 ASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 589 +K A Y+ASK ++ LT+A A+ELGP+GIRVN + P I+ E Sbjct: 143 CNKLAFPKLVSYTASKGGIEQLTKASAVELGPHGIRVNCVAPGAILNE 190 >UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=19; Bacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Bacillus anthracis Length = 242 Score = 90.6 bits (215), Expect = 3e-17 Identities = 55/190 (28%), Positives = 98/190 (51%), Gaps = 8/190 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV----DI 217 +GK L+T L + G N+ L+R+ +L+++ E + + V D+ Sbjct: 9 QGKNALITGAGRGIGRAVAIALAKEGVNVGLLARSEENLKAVAKEVEAEGVKAVIATADV 68 Query: 218 GDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 +E+ +E+L G D L+NNA ++ FL+ ++++K VN+ V ++ Sbjct: 69 SSYEEVTTAIETLKNGLGSIDILINNAGISKFGKFLELDVADWEKIIQVNLMGVYYATRA 128 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 MIE ++ G I+NISS A + + YSASK + LT ++A+E+ + IRV A+ Sbjct: 129 ALPSMIEQQS-GDIINISSTAGQKGAPVTSAYSASKFGVLGLTESLAMEVRKHNIRVTAL 187 Query: 566 NPTVIMTEMA 595 P+ + T+MA Sbjct: 188 TPSTVATDMA 197 >UniRef50_A0VRG5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Rhodobacteraceae|Rep: Short-chain dehydrogenase/reductase SDR precursor - Dinoroseobacter shibae DFL 12 Length = 247 Score = 90.6 bits (215), Expect = 3e-17 Identities = 50/123 (40%), Positives = 70/123 (56%) Frame = +2 Query: 272 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 451 LVNNA +A FLD + FD+ D+N++ V +Q R M+ + GA+VN+SS + Sbjct: 79 LVNNAGIAAPGDFLDYDLATFDRVLDINLRGVFVATQRAGRSMVAHGIKGAVVNMSSINA 138 Query: 452 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKANE 631 + A+ Y ASK L LT+ AL L P+GIRVNA+ P I TEM ++P N Sbjct: 139 QVAIPSIPAYCASKGGLMQLTKVAALALAPHGIRVNAVGPGSIDTEMMAGVNANPEAMNM 198 Query: 632 MLS 640 +LS Sbjct: 199 VLS 201 >UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR precursor - Clostridium phytofermentans ISDg Length = 258 Score = 90.2 bits (214), Expect = 4e-17 Identities = 65/192 (33%), Positives = 98/192 (51%), Gaps = 12/192 (6%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDVDIG 220 GK +VT +AGA++ L+R L +++E I V D+ Sbjct: 9 GKVAVVTGASSGLGADAALAYAKAGADVALLARRIEKLNEVKAEIEKIGRKVVAVGCDVT 68 Query: 221 DWEKTRK----VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 + E + V+++ GH D L+NNA +AV S ++DK++D NVK + S+ V Sbjct: 69 NEESVKTAMQTVIDTFGHIDILLNNAGIAVRGGVDSMSVEDWDKSYDTNVKGIFLASKYV 128 Query: 389 ARKMIENKTHGAIVNISSQASKAALK-DHTI---YSASKAALDALTRAMALELGPYGIRV 556 +M E + +G I+NI+S + A K D I Y++SKAA+ LTR MA YGI V Sbjct: 129 VPQMKE-RGYGKIINIASVNAVVADKFDAFIRHSYNSSKAAVVGLTRGMAASYARYGITV 187 Query: 557 NAINPTVIMTEM 592 NAI P + +EM Sbjct: 188 NAIGPALFESEM 199 >UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 249 Score = 90.2 bits (214), Expect = 4e-17 Identities = 61/202 (30%), Positives = 97/202 (48%), Gaps = 11/202 (5%) Frame = +2 Query: 62 ILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI----DIVDVDIGDWE 229 +LVT + GAN+V R +SL +E ++ + + D+ + Sbjct: 6 VLVTGALTGIGRATAIAFAKQGANVVVSGRREEAGQSLAAELRTLGAKAEFIKADVANEA 65 Query: 230 KTRKVVES----LGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 + R +VE G D +NNA P + S N TF NV L +S Sbjct: 66 EVRSLVEKAVSLFGQLDIAINNAGTEGALGPITEQSTENVHATFSTNVLGTL-LSMKHEI 124 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 + ++ + HG+IVN+SS A K + ++Y ASK A++ LT++ ALE +G+RVNA+ P Sbjct: 125 RAMQAQGHGSIVNLSSIAGKVGMAGASVYVASKHAVEGLTKSAALEGAAFGVRVNAVAPG 184 Query: 575 VIMTEMAK--VGWSDPIKANEM 634 + T+M VG + +KA M Sbjct: 185 PVQTDMLDRFVGRDESVKAGFM 206 >UniRef50_A1B7W8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Paracoccus denitrificans PD1222|Rep: Short-chain dehydrogenase/reductase SDR - Paracoccus denitrificans (strain Pd 1222) Length = 261 Score = 90.2 bits (214), Expect = 4e-17 Identities = 65/200 (32%), Positives = 105/200 (52%), Gaps = 5/200 (2%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDW-- 226 G+ +VT L AGA+++A+ R + +E+L + P + V D+ D Sbjct: 9 GRTAIVTGAGQGIGLAIAEALLAAGAHVLAVDREAAGIEALAAR-PGVTAVLGDVTDPGL 67 Query: 227 -EKTRKVVESL-GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 E+ V++ D LVNNA +A L +F + FD+NV + +S+ ++M Sbjct: 68 PEQIGAVLDGARARLDILVNNAGIARGAHALHTGDEDFTRYFDINVLGLFRLSRWAVQRM 127 Query: 401 IENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVI 580 ++ GAIVN +S ++ YSASKAA+ LTR MA + GP GIRVNA+ P +I Sbjct: 128 MD-AGGGAIVNTASIFGLIGAQNSCGYSASKAAVIGLTRQMATDFGPNGIRVNAVAPGLI 186 Query: 581 MTEM-AKVGWSDPIKANEML 637 T + A+ S+P + ++M+ Sbjct: 187 ETPLTAERIRSEPWRRHQMI 206 >UniRef50_Q97RW1 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=39; Streptococcus|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Streptococcus pneumoniae Length = 251 Score = 89.8 bits (213), Expect = 5e-17 Identities = 51/155 (32%), Positives = 82/155 (52%), Gaps = 4/155 (2%) Frame = +2 Query: 134 IVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVC 301 ++ L R + L L Y +++++DI D +V L G D L+NNA + Sbjct: 26 LILLGRNKEKLAQLYGNYSHAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIF 85 Query: 302 EPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIY 481 E F + + + F+VN A++N+S+ +A +M E+ + G I+NI S A A ++Y Sbjct: 86 EGFDQIADKDIHQMFEVNTFALMNLSRHLAARMKES-SKGHIINIVSMAGLIATGKSSLY 144 Query: 482 SASKAALDALTRAMALELGPYGIRVNAINPTVIMT 586 SA+K A + A+ LEL PYG+ V +NP I T Sbjct: 145 SATKFAAIGFSNALRLELMPYGVYVTTVNPGPIRT 179 >UniRef50_Q89CB1 Cluster: Bll7886 protein; n=8; Bradyrhizobiaceae|Rep: Bll7886 protein - Bradyrhizobium japonicum Length = 253 Score = 89.8 bits (213), Expect = 5e-17 Identities = 63/193 (32%), Positives = 92/193 (47%), Gaps = 8/193 (4%) Frame = +2 Query: 62 ILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDIVDVDIGDWE 229 ILVT L GA + +R L++L+ E V +D+ D Sbjct: 12 ILVTGASQGLGRQFARLLAAHGAAVALAARQTDKLKNLEQEIRGNGGRAAAVALDVTDIA 71 Query: 230 KTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 K V++ LG L+NNA +A+ + + + +++D N+K ++ VAR+ Sbjct: 72 SIAKAVDATEAALGPVTVLINNAGIAIEKLATEQTEADWDTVIGANLKGAYFLATEVARR 131 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 MI K G IVNI+S LK + Y+ SKA + T+AMALEL IR+NA+ P Sbjct: 132 MIARKQEGNIVNIASVLGTGVLKAVSPYAISKAGIIQATKAMALELAGQNIRINALAPGY 191 Query: 578 IMTEMAKVGWSDP 616 I TEM WS P Sbjct: 192 IDTEMNHAFWSTP 204 >UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase; n=6; Bacteria|Rep: 2-keto-3-deoxygluconate oxidoreductase - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 253 Score = 89.8 bits (213), Expect = 5e-17 Identities = 60/173 (34%), Positives = 91/173 (52%), Gaps = 2/173 (1%) Frame = +2 Query: 125 GANIVALSRTRSHLESLQSEYPSI--DIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAV 298 G NIV T + +L + S+ D+ +V G E K V GH D LVNNA + Sbjct: 39 GVNIVEPKDTIEKVTALGRRFLSLTADMSNV-AGHAELVEKAVAEFGHVDILVNNAGIIR 97 Query: 299 CEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTI 478 E ++ S N+D ++N+K+V +SQ VAR+ I+ G I+NI+S S Sbjct: 98 REDAIEFSEKNWDDVMNLNIKSVFFMSQAVARQFIKQGKGGKIINIASMLSFQGGIRVPS 157 Query: 479 YSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKANEML 637 Y+ASK+A+ +TR +A E +GI VNAI P + T + +D ++ E+L Sbjct: 158 YTASKSAVMGVTRLLANEWAKHGINVNAIAPGYMATNNTQQLRADEDRSKEIL 210 >UniRef50_Q15RB1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 241 Score = 89.8 bits (213), Expect = 5e-17 Identities = 57/183 (31%), Positives = 94/183 (51%), Gaps = 6/183 (3%) Frame = +2 Query: 62 ILVTXXXXXXXXXXXXELWRAGANIVALSRTRS-HLESLQSEYPSI-DIVDVDIGDWEKT 235 ++VT +L +G ++VAL+RT S L SL YP ++ D+ D + Sbjct: 5 VIVTGASRGLGLAICRDLLDSGVSVVALARTYSPELHSLSDAYPDCCHFIEADLADLDAL 64 Query: 236 ----RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 403 + +V+ G LVNNAAV D +NV++ + +S+ + R M+ Sbjct: 65 PALCKSIVKRFGRPYGLVNNAAVGHDGVLATMPNGEIDNLMRLNVQSPMLLSKYLLRSML 124 Query: 404 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 583 N+ G I+NISS +K ++Y+ASKAAL+ ++++A E+G GI VN + P + Sbjct: 125 LNR-RGRIINISSIIAKTGFNGLSVYAASKAALEGFSKSLAREVGKAGITVNCVAPGYMQ 183 Query: 584 TEM 592 T+M Sbjct: 184 TDM 186 >UniRef50_Q12JI9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Shewanella|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) Length = 257 Score = 89.8 bits (213), Expect = 5e-17 Identities = 63/190 (33%), Positives = 94/190 (49%), Gaps = 8/190 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVD-- 214 GK++LVT L + GA I+ R ++ LE SL I + D+ Sbjct: 14 GKQVLVTGASAGIGRACCTLLSQLGAKIILTGRNQAGLEETLSSLSGNGHKIAVFDIKNI 73 Query: 215 --IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 +GDW K + G+ D+ V+ A V + +P FD T VN+ + + I+Q Sbjct: 74 NGLGDWVKYLR--SEYGYLDSFVHCAGVQITKPIRSFDQGFFDDTMHVNLASAMAITQGF 131 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 K +K G+IV +SS A +T+Y ASKA L +LTR +A+EL IRVN + Sbjct: 132 RLKRDRSK-QGSIVFVSSIAGLIGQTGNTVYGASKAGLMSLTRGLAMELLRDNIRVNCVA 190 Query: 569 PTVIMTEMAK 598 P ++ TEMA+ Sbjct: 191 PALVETEMAQ 200 >UniRef50_Q11EZ4 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mesorhizobium sp. (strain BNC1) Length = 254 Score = 89.8 bits (213), Expect = 5e-17 Identities = 62/205 (30%), Positives = 96/205 (46%), Gaps = 7/205 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP----SIDIVDV 211 S +G+R LVT L AGA+IV SR+R LE Q S +IV Sbjct: 7 SLQGRRALVTGAGRGIGQAIAVALSDAGADIVLTSRSREQLEETQKRITDAGGSAEIVQG 66 Query: 212 DIGDWEKTRKVV---ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 D+ E+ ++V E G D +V++A EP + + +D VN+ A +SQ Sbjct: 67 DLSQAERLTELVDAAEERGPLDIVVHSAGAQHREPAVTFPKAAWDHVIGVNLTAPFLLSQ 126 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 + R+ + + G+ V + S S L D Y+A+K+ L + RA++ E GIR N Sbjct: 127 EIGRRQLAHGRKGSHVFVCSLTSILGLPDLVAYNAAKSGLMGVVRALSREWSSKGIRFNG 186 Query: 563 INPTVIMTEMAKVGWSDPIKANEML 637 ++P + T M + DP K +L Sbjct: 187 VSPGYVETAMTAALFKDPAKRQRLL 211 >UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteria|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 260 Score = 89.8 bits (213), Expect = 5e-17 Identities = 63/197 (31%), Positives = 98/197 (49%), Gaps = 4/197 (2%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 214 M+ G +LVT RAGA +VA +R R ++ + +I+ + D Sbjct: 1 MDSGLNGAIVLVTGGVRGVGAGISRTFLRAGATVVACAR-RPGEAPVEVDGRAIEFLPCD 59 Query: 215 IGDWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 I D E+ + ++VE G D LVNNA A D SP K ++N+ A L +SQ Sbjct: 60 IRDPEQVQGLVDRIVERHGRLDVLVNNAGGAPFALAADASPKFHSKIVELNLLAPLLVSQ 119 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 M + + GAIVNISS + Y A+KA +D+LT ++A+E P +RVN+ Sbjct: 120 TANAVMQKQDSGGAIVNISSVSGSRPSPGTAAYGAAKAGVDSLTGSLAVEWAP-KVRVNS 178 Query: 563 INPTVIMTEMAKVGWSD 613 + ++ TE+A + + D Sbjct: 179 VVVGLVRTELAHLHYGD 195 >UniRef50_A5V7U7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Sphingomonas wittichii RW1 Length = 252 Score = 89.8 bits (213), Expect = 5e-17 Identities = 50/139 (35%), Positives = 77/139 (55%), Gaps = 4/139 (2%) Frame = +2 Query: 188 PSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVN 355 P +++D+ D + V ++ G D LVN A +P+L+ P +D+ F VN Sbjct: 51 PPARAIELDVSDPAAVGRTVAAIDAEAGGIDLLVNAAGRYALQPWLEIEPETWDRIFAVN 110 Query: 356 VKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALEL 535 + ++ +Q VAR M G+I+NI+S A + + YSASKAA ++T++ AL L Sbjct: 111 TRGIMLTTQAVARVMAARGKGGSIINIASAAGRRGDPNSVAYSASKAAAISITQSAALGL 170 Query: 536 GPYGIRVNAINPTVIMTEM 592 P+GIRVNAI P + T M Sbjct: 171 APHGIRVNAIAPGPVDTPM 189 >UniRef50_Q393N0 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 267 Score = 89.4 bits (212), Expect = 6e-17 Identities = 63/191 (32%), Positives = 96/191 (50%), Gaps = 9/191 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIG 220 G+ LVT R GA +V R + L+ ++ + +D+G Sbjct: 20 GRVALVTGGGTGIGRAAALAFAREGARVVVAGRRAAPLDETVHAIAERGGEAFAMAIDVG 79 Query: 221 DWEKTRKVVES-LGHFDAL---VNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + R +V++ +G + AL NNA P ++ + ++FD+ N+K + Sbjct: 80 SADGVRALVDTTIGRYGALHAAFNNAGTEGTFAPIVEQTEADFDQVIATNLKGTWLSIKY 139 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 M+ + GAIVN SS +K AL + YSASK ALDAL RA+ALE GP+GIR+N + Sbjct: 140 EMEAMLAHGG-GAIVNTSSWLAKGALAGSSTYSASKGALDALVRAVALEGGPHGIRINNV 198 Query: 566 NPTVIMTEMAK 598 NP +I T MA+ Sbjct: 199 NPGIIDTPMAR 209 >UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 516 Score = 89.4 bits (212), Expect = 6e-17 Identities = 58/188 (30%), Positives = 90/188 (47%), Gaps = 7/188 (3%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRS----HLESLQSEYPSIDIVDVDI 217 + + +LVT RAG +V R + E L S + ++ + D Sbjct: 9 RARLVLVTGAARGIGLACAHRFARAGDRVVMADRDLAACTFEAERLGSRHVALQLDVSDE 68 Query: 218 GDWEKTRK-VVESLGHFDALVNNAAVA--VCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 E +++ G FD ++NNA V P LD P + D+ VN++ + + Sbjct: 69 AAVEHAMDGLLQQFGAFDVVINNAGVVDRFARPLLDVPPEDIDRLIGVNLEGPYLVVRAA 128 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 R ++ + AIVN++S A+ AL YS +KA + +TRAMA+ELGP GI VNA+ Sbjct: 129 LRTILAGRRGAAIVNVASGAALRALPGRAAYSMTKAGVIGMTRAMAIELGPQGIAVNAVL 188 Query: 569 PTVIMTEM 592 P I TE+ Sbjct: 189 PGYIDTEI 196 Score = 80.2 bits (189), Expect = 4e-14 Identities = 49/118 (41%), Positives = 68/118 (57%), Gaps = 3/118 (2%) Frame = +2 Query: 242 VVESLGHFDALVNNAAVAVCEPFL---DCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 412 + LG LVNNA + EP D + ++F +T DVNVK ++ S+ AR+MI Sbjct: 332 IAGQLGPVTLLVNNAGIV--EPMAKSADQALADFRRTIDVNVKGTIHASRAAARQMI-GA 388 Query: 413 THGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT 586 GAIVN+SS + L Y ASK+A+ LTR++A E +GIRVNA+ P I+T Sbjct: 389 GGGAIVNLSSITASLGLPGRNAYCASKSAVTMLTRSLACEWAAHGIRVNAVAPGYILT 446 >UniRef50_Q89NC8 Cluster: Oxidoreductase; n=1; Bradyrhizobium japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 269 Score = 89.0 bits (211), Expect = 8e-17 Identities = 59/185 (31%), Positives = 89/185 (48%) Frame = +2 Query: 32 KMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV 211 KM KGKR ++T R GA ++A S + L E + + + Sbjct: 26 KMADRLKGKRAVITAAAAGIGRACAIAFAREGATVIATDINESGIAGLAKEGIA-ETAKL 84 Query: 212 DIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 D+ + + +G D L+N A L+CS +FD +FD+NVK++ + Sbjct: 85 DVRNTADVNAFAKRVGKIDILLNAAGFVHHGTILECSEEDFDFSFDLNVKSMHRTIRAFL 144 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 M+ G+IVNISS A+ + +YSASKAA+ LTRA+AL+ GIR N+I P Sbjct: 145 PDMLAGGG-GSIVNISSCAALRPPANRYVYSASKAAVSLLTRAVALDFITKGIRCNSICP 203 Query: 572 TVIMT 586 + T Sbjct: 204 GTVET 208 >UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succiniciproducens MBEL55E|Rep: FabG protein - Mannheimia succiniciproducens (strain MBEL55E) Length = 248 Score = 89.0 bits (211), Expect = 8e-17 Identities = 56/184 (30%), Positives = 92/184 (50%), Gaps = 4/184 (2%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDW 226 F+ K LVT L + GA ++ + RT L+ + +P+I DI Sbjct: 4 FEQKTALVTGAGTGIGQAIAVRLAQEGAKVLVVGRTEKTLQETTALHPNIAYAVADIEKD 63 Query: 227 EKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 + +K+V+ L G D L+NNA A P +DK F +NV+A++N++ Sbjct: 64 DDVQKIVQQLNQKYGGLDILINNAGWAPVTPISQVKIEEYDKVFGINVRALVNLTLQCLP 123 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 + K G I+N+SS + L + ++Y+ +KAA++ T+ A ELG G+RVN+I+ Sbjct: 124 MLKARK--GNIINMSSAICRNHLPNMSMYAGTKAAVEIFTKIWAKELGADGVRVNSISVG 181 Query: 575 VIMT 586 I T Sbjct: 182 PIET 185 >UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep: CylG - Streptococcus agalactiae Length = 240 Score = 89.0 bits (211), Expect = 8e-17 Identities = 52/184 (28%), Positives = 92/184 (50%), Gaps = 5/184 (2%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTR-SHLESLQSEYPSIDIVDVDIGDWEK 232 K +VT EL++ G ++A+ + + +LQ E P +D+ +I D + Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEELPKLDVYKCNISDAKA 61 Query: 233 TRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 +K+V + G D LVNNA + FL S + ++N+ ++N+S+ V + M Sbjct: 62 VQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKAVLKIM 121 Query: 401 IENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVI 580 + G ++NISS + A YSA+K A+ ++T+ +A E GI +N ++P I Sbjct: 122 KAKRIQGKVINISSTSGIAGQIGQANYSATKGAIISITKTLAKEFASDGITINCVSPGFI 181 Query: 581 MTEM 592 T+M Sbjct: 182 ETDM 185 >UniRef50_Q6W1M4 Cluster: Putative uncharacterized protein; n=1; Rhizobium sp. NGR234|Rep: Putative uncharacterized protein - Rhizobium sp. (strain NGR234) Length = 230 Score = 89.0 bits (211), Expect = 8e-17 Identities = 53/173 (30%), Positives = 92/173 (53%) Frame = +2 Query: 122 AGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVC 301 AGA+++ ++R LE+L E S + VD+ D + +G D LVNN+ Sbjct: 20 AGADVIPVARGGEALETLADELGSAPLA-VDLTDPAVISSAMNGIGPVDVLVNNSGTNRP 78 Query: 302 EPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIY 481 PF + +FD ++N++ +Q + + + GAI+N+ SQ ++ T+Y Sbjct: 79 GPFEAVTVQDFDLLVNLNLRGTFFATQSLLPHI---RAGGAILNVGSQMGHVGAENRTVY 135 Query: 482 SASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKANEMLS 640 A+K A++ T+A+A+EL P IRV +I PT I T M ++DP +++L+ Sbjct: 136 CATKHAIEGFTKALAIELAPRAIRVVSIAPTFIETPMTAPMFADPTFRSQVLT 188 >UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Clostridium perfringens|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 272 Score = 89.0 bits (211), Expect = 8e-17 Identities = 56/191 (29%), Positives = 89/191 (46%), Gaps = 9/191 (4%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSR----TRSHLESLQSEYPSIDIVDVD 214 F K +++T + GA +V R ++ L+ ++ +++ + D Sbjct: 9 FSDKVMIITGAAGGIGKAVALRAAKEGAKLVLADRKEEMSKETLKEIREITSNVEFLICD 68 Query: 215 IGDWEKTRKVVES----LGHFDALVNNAAVA-VCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 + + E +KV+++ G D L+NNA + P + S F D N+ + S Sbjct: 69 LREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFHCS 128 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 ++MI+ GAIVN+SS A H+ Y SK L+ LTR MAL+ YGIRVN Sbjct: 129 HYGIQEMIKQNKGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMALDYARYGIRVN 188 Query: 560 AINPTVIMTEM 592 A+NP T M Sbjct: 189 AVNPGTTDTPM 199 >UniRef50_A3PZB7 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 263 Score = 89.0 bits (211), Expect = 8e-17 Identities = 52/118 (44%), Positives = 67/118 (56%), Gaps = 1/118 (0%) Frame = +2 Query: 242 VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHG 421 V + LG DA VNNA V+ E F+D +P +D+T D+N KAV Q AR MI G Sbjct: 80 VADRLG-LDAWVNNAGVSAMERFVDVTPGQYDRTLDINTKAVFFCGQAAARAMIRTGRQG 138 Query: 422 AIVNISSQASK-AALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 IVN +S A+K + T Y ASK A+ LT+AMA EL + I VN + P + T M Sbjct: 139 TIVNTASMAAKQGRVPFLTDYVASKFAVLGLTQAMAYELADHQITVNCVCPGFVATPM 196 >UniRef50_Q46MD0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 88.6 bits (210), Expect = 1e-16 Identities = 65/192 (33%), Positives = 95/192 (49%), Gaps = 9/192 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES-----LQSEYPSIDI-V 205 S GK ++ + AGA +V +R S LE L + Y + + + Sbjct: 9 SLHGKAAFISGASSGIGLHVAELMAEAGAKVVLAARRASLLEDHVERLLTAGYVASSVPL 68 Query: 206 DV-DIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 DV D G ++ ES G D L NNA V E FL P + D+ FD+N + + Sbjct: 69 DVSDSGSIAESWCQAESQVGGQIDILFNNAGVIYTERFLSQQPEDIDRVFDINFRGAFLL 128 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 +Q A+ M ++ G+I+N++S + A T Y ASKAAL +LT+ MALEL G+RV Sbjct: 129 AQQAAKGMAARRS-GSIINVASTSGLRAGGYMTSYGASKAALISLTQTMALELAGKGVRV 187 Query: 557 NAINPTVIMTEM 592 NA+ P T+M Sbjct: 188 NALCPGNFRTDM 199 >UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Herpetosiphon aurantiacus ATCC 23779 Length = 257 Score = 88.6 bits (210), Expect = 1e-16 Identities = 68/199 (34%), Positives = 98/199 (49%), Gaps = 12/199 (6%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID-------IVDV 211 GK +VT +AGA +V +R LESLQ+ SI+ + Sbjct: 8 GKVAIVTGASRGIGEAIAQHFAQAGAKVVVCARK---LESLQTVADSINQAGGTALAMAC 64 Query: 212 DIGDWEKTRKVVESL----GHFDALVNNAAVAV-CEPFLDCSPSNFDKTFDVNVKAVLNI 376 G E+ + VV G D +VNNAA P L+ S +DKT++VNVK + Sbjct: 65 HTGKPEQVQAVVAQTLAEWGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYFWL 124 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 Q A M + + G+I+N++S A IYS SKAA+ A+T+ +A ELGP IRV Sbjct: 125 IQAAAEAM-QAQGGGSIINVASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIRV 183 Query: 557 NAINPTVIMTEMAKVGWSD 613 NA+ P +I T+ + W + Sbjct: 184 NALAPGLIKTKFSSALWDN 202 >UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 266 Score = 88.6 bits (210), Expect = 1e-16 Identities = 60/202 (29%), Positives = 100/202 (49%), Gaps = 8/202 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDIVDV 211 S +G+ +VT L AGA+++ +R + L + E + IV Sbjct: 6 SLEGRTAMVTGASRGLGRAIALGLADAGASLILAARDAAKLGEVADEVRAKGRDARIVTF 65 Query: 212 DIGDWEKT----RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ D R +V+ D LVNN +A P S ++++TFDVNV A+ + Sbjct: 66 DLADMASVEAAARGLVDEGAPIDILVNNGGIAEWGPLHGSSLDHWERTFDVNVSAIYLLC 125 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + +++ M E + G I+N +S ++ + + Y ASK A+ LTRA+A +L P+G+ N Sbjct: 126 RELSKPMAE-RGWGRIINFASYVAETGRPNLSAYVASKHAVLGLTRAVAADLAPHGVTCN 184 Query: 560 AINPTVIMTEMAKVGWSDPIKA 625 AI P + +T+MA P +A Sbjct: 185 AIAPGIFLTDMAAPTAGHPQRA 206 >UniRef50_A3J7V6 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinobacter sp. ELB17 Length = 266 Score = 88.6 bits (210), Expect = 1e-16 Identities = 58/188 (30%), Positives = 92/188 (48%), Gaps = 8/188 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDIVDVDIG 220 GK L+T L GA ++ R L+ L+SE+P I IV +D+ Sbjct: 20 GKIALITGAAGGLGQSFTRCLLDTGATVIVSGRRCEALKRLKSEFPDHSDRIHIVPMDVS 79 Query: 221 DWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 D + + + G D +V NA VA+ + L+C+ ++D D N+K ++ Sbjct: 80 DELSVTQAFDVMAARVGIPDVVVANAGVAISKKALNCTGDDWDSVVDTNLKGCWLVATEA 139 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 AR++ G+I+ ISS A + Y+ +KA ++ LTR +ALE YGIRVNA+ Sbjct: 140 ARRLSGEGRRGSIIMISSILGHRAAGNVAPYAVAKAGVEQLTRVLALEWARYGIRVNALA 199 Query: 569 PTVIMTEM 592 P I T++ Sbjct: 200 PGYIETDL 207 >UniRef50_P0A2D1 Cluster: Oxidoreductase ucpA; n=21; Bacteria|Rep: Oxidoreductase ucpA - Salmonella typhimurium Length = 263 Score = 88.6 bits (210), Expect = 1e-16 Identities = 66/191 (34%), Positives = 92/191 (48%), Gaps = 9/191 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDIVDVDIG 220 GK L+T R GAN++ L + +E L E V D+ Sbjct: 6 GKTALITGASQGIGEGIARVFARHGANLILLDIS-DEIEKLADELGGRGHRCTAVKADVR 64 Query: 221 DWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 D+ + V E+ G D LVNNA V FLD S + D D+N+K V N+++ V Sbjct: 65 DFASVQAAVARAKETEGRIDILVNNAGVCRLGNFLDMSEEDRDFHIDINIKGVWNVTKAV 124 Query: 389 ARKMIENKTHGAIVNISS-QASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 +MI+ K G IV +SS A T Y+ SKAA+ LT+++A+E GIRVNAI Sbjct: 125 LPEMIKRK-DGRIVMMSSVTGDMVADPGETAYALSKAAIVGLTKSLAVEYAQSGIRVNAI 183 Query: 566 NPTVIMTEMAK 598 P + T MA+ Sbjct: 184 CPGYVRTPMAE 194 >UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Rep: Blr3449 protein - Bradyrhizobium japonicum Length = 256 Score = 88.2 bits (209), Expect = 1e-16 Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 1/151 (0%) Frame = +2 Query: 191 SIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPF-LDCSPSNFDKTFDVNVKAV 367 S+D+ D + E R+V E LG D +VNNA + + EP + N+ + FDVNV Sbjct: 68 SLDVTDA-LACGEVARRVDEELGLADVVVNNAGIIIREPIDSPRAHENWRQVFDVNVNGT 126 Query: 368 LNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 547 N+ + K+ G I+N++S A+ ++ YS+SK A+ T+A+A +L P G Sbjct: 127 FNVVHAFIPAL--RKSPGTIINVASVAAFGSMGGTVGYSSSKGAVRLFTQALARDLAPDG 184 Query: 548 IRVNAINPTVIMTEMAKVGWSDPIKANEMLS 640 IRVNA+ P +I TEM++ +P + + +++ Sbjct: 185 IRVNAVAPGIIATEMSESTRGNPARLSGLMA 215 >UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketoreductase - Symbiobacterium thermophilum Length = 241 Score = 88.2 bits (209), Expect = 1e-16 Identities = 57/155 (36%), Positives = 77/155 (49%), Gaps = 4/155 (2%) Frame = +2 Query: 119 RAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNA 286 R GA ++ R L ++ P I V D+ R+VVE G D +VNNA Sbjct: 20 RRGAKVLITGRRPEPLRETEAAAPGIRGVTADVTVASDARRVVEEAAKLWGRIDVVVNNA 79 Query: 287 AVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALK 466 + PF + F NV +N+ + + E++ GAI+N+SS A Sbjct: 80 GMFASGPFEKVGAETAAQLFATNVFGPINLVREALPWLKESR--GAIINVSSTYGHKAAA 137 Query: 467 DHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 + Y+ASKAALD LTR ALEL PYGIRVNA+ P Sbjct: 138 NVAHYAASKAALDHLTRCWALELAPYGIRVNAVAP 172 >UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Geobacillus kaustophilus Length = 256 Score = 88.2 bits (209), Expect = 1e-16 Identities = 60/194 (30%), Positives = 97/194 (50%), Gaps = 14/194 (7%) Frame = +2 Query: 65 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV------DIGDW 226 ++T L + GA +V + RT LE + + + V D+ D Sbjct: 9 VITGGGSGIGRATAVRLAQEGATVVLVGRTAVKLEETVQDITRLGVPGVADRFAADVTDH 68 Query: 227 EKTRK----VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 E+ R V G LVNNA ++ +L+ + +D VN+K+V +SQ +A Sbjct: 69 EQVRALAAYVQNRYGDLHVLVNNAGISTHTKWLELTEQEWDDVQRVNMKSVFLVSQTLAP 128 Query: 395 KMIEN----KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 MIE + + AIVN++S + A + YSA+KA + LT+++ALEL PYGIRVN+ Sbjct: 129 LMIEGAKRERANRAIVNVASLSGHQAGAEIPHYSAAKAGVINLTKSLALELAPYGIRVNS 188 Query: 563 INPTVIMTEMAKVG 604 ++P + T + + G Sbjct: 189 VSPGFVETPLTERG 202 >UniRef50_Q5FKH2 Cluster: Oxidoreductase, short chaindehydrogenase-reductase; n=6; Lactobacillus|Rep: Oxidoreductase, short chaindehydrogenase-reductase - Lactobacillus acidophilus Length = 264 Score = 88.2 bits (209), Expect = 1e-16 Identities = 54/198 (27%), Positives = 92/198 (46%), Gaps = 9/198 (4%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----- 199 M+ S + K +++T E GA ++ ++R + LE + +E + Sbjct: 1 MKDSLRNKVVVITGASSGIGRSIALESAGRGATVILIARRKDRLEEITAEAKELSGAEAY 60 Query: 200 IVDVDIGDWEKTRK----VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAV 367 + D+G E K + + + H D LVN A E F++ + F VNV + Sbjct: 61 VFPTDMGKPESIEKTFDEITKQVKHIDFLVNCAGFGKFEEFMEQKMQDVTNMFQVNVLGL 120 Query: 368 LNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 547 + ++++ R M++ KT G I+N S A K YSASKAA+ + + LEL P+G Sbjct: 121 MYFTRLIGRVMMDQKT-GQIINFGSIAGKVPTTKSAAYSASKAAVIQFSNVLRLELKPFG 179 Query: 548 IRVNAINPTVIMTEMAKV 601 ++V +NP + T V Sbjct: 180 VKVMTVNPGPVYTNFFNV 197 >UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=2; Candidatus Pelagibacter ubique|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Pelagibacter ubique Length = 245 Score = 88.2 bits (209), Expect = 1e-16 Identities = 55/188 (29%), Positives = 93/188 (49%), Gaps = 5/188 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGD 223 S K K I+VT +L + GANI+A LE L+ ++ +I I+ DI Sbjct: 3 SLKDKNIIVTGASGGIGNSIVEKLNQNGANILATGTRIEKLEELKEKFNNIKILKFDISQ 62 Query: 224 WEKTRKVVESL-----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 +K + +E+ G D +VNNA + + S + K ++N+ + + + Sbjct: 63 HDKIEEFIENATKELGGSLDCIVNNAGITKDNLTIRMSLEEWSKVININLTSTFLMCKYS 122 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 +KM++NK+ G I+NI+S Y+ASKA + A+++++A+E I VN I+ Sbjct: 123 IKKMLKNKS-GKIINITSVVGHTGNVGQANYTASKAGIVAMSKSLAIEYAKKNINVNCIS 181 Query: 569 PTVIMTEM 592 P I T M Sbjct: 182 PGFISTAM 189 >UniRef50_Q392C0 Cluster: Short-chain dehydrogenase/reductase SDR; n=38; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 239 Score = 88.2 bits (209), Expect = 1e-16 Identities = 59/179 (32%), Positives = 94/179 (52%), Gaps = 3/179 (1%) Frame = +2 Query: 65 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKV 244 LVT L R G +++ L+R H + + ++P +++ D+ D E+T Sbjct: 7 LVTGASRGIGLAVSTLLARHGHHVIGLAR---HAQGI--DFPG-ELLACDLADIEQTAAT 60 Query: 245 VESLGH---FDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 + + D +VNNA + + +P + FD+NV+A + ++Q A M + + Sbjct: 61 LARISEQHDVDGIVNNAGIVLPQPLGQIDFQSLQTVFDLNVRAAIQVTQHFADAM-KARG 119 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 HG IVNI S+A +L D T YSA+K+AL TR ALEL +G+ VNA+ P I TE+ Sbjct: 120 HGRIVNICSRAIFGSL-DRTAYSAAKSALVGCTRTWALELAEHGVTVNAVAPGPIETEL 177 >UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 251 Score = 88.2 bits (209), Expect = 1e-16 Identities = 46/127 (36%), Positives = 69/127 (54%) Frame = +2 Query: 236 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 + V ++ GH DA+VNNA + + ++D DVN K + Q V M++ + Sbjct: 76 KAVGDAFGHLDAVVNNAGILISGDVEGLDEEHWDSVMDVNAKGTFLVVQAVL-PMMKARR 134 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA 595 +G IVNI+S K + YSASKAA+ TR +A E+G GI N + P +I+T+M Sbjct: 135 YGRIVNIASIGGKHGAPEQAHYSASKAAVMGFTRVLAQEVGVDGITANCVCPGIILTDMG 194 Query: 596 KVGWSDP 616 +V DP Sbjct: 195 RVNLDDP 201 >UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Saccharopolyspora erythraea (strain NRRL 23338) Length = 253 Score = 88.2 bits (209), Expect = 1e-16 Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 6/186 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI------DIVDVD 214 G+ +VT L GA +V R R +E L ++ P D+ D D Sbjct: 12 GRVAVVTGAARGIGRATAALLRERGARLVVTDR-REAVEELAADDPDDVAALVGDVADED 70 Query: 215 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 I TR + G D LVNNA + +P D + +FD+ VN + ++ R Sbjct: 71 IAR-AATRLATQRFGRLDILVNNAGRTLNKPVTDTTVDDFDEIMRVNARGNFVQAREAFR 129 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 M E GAIV+I+S +S A + T Y+ASK AL +TR +A+E GP GIR NA+ P Sbjct: 130 AM-EAGGGGAIVSIASVSSVVAFRTQTAYAASKGALAQITRVLAIEGGPKGIRSNAVLPG 188 Query: 575 VIMTEM 592 V+ T++ Sbjct: 189 VVDTDI 194 >UniRef50_A3YG01 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 265 Score = 88.2 bits (209), Expect = 1e-16 Identities = 46/126 (36%), Positives = 71/126 (56%) Frame = +2 Query: 194 IDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 ++++++D+ D +VES+G DALVNNA + PF S N + F+ N AV Sbjct: 63 LELLELDVTDATSIANLVESVGTIDALVNNAGIGWLSPFEGTSDENVRRIFETNTFAVFE 122 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 + + + KM + G IVN+SS + L +Y+ASKAA++A T ++LEL P GIR Sbjct: 123 MIRALLPKM-RQQGEGVIVNVSSSVTMKPLPLLAVYTASKAAVNAYTECLSLELAPLGIR 181 Query: 554 VNAINP 571 + P Sbjct: 182 TRLVLP 187 >UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 255 Score = 88.2 bits (209), Expect = 1e-16 Identities = 66/200 (33%), Positives = 94/200 (47%), Gaps = 10/200 (5%) Frame = +2 Query: 32 KMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSH----LESLQSEYPSID 199 K G+ LVT L +AGA + R+ +E +E ++ Sbjct: 4 KNPFDLTGRTALVTGGNQGLGRAFAFGLAQAGATVAISGRSAERNAKVVEEAAAEGFALH 63 Query: 200 IVDVDI---GDWEK-TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAV 367 + DI D ++ T + + +LGH D LVNNA D + +D FD+NVKA+ Sbjct: 64 PITADITRQDDVDRMTAEAISALGHLDILVNNAGTCYHAESWDVTEEQWDSVFDLNVKAL 123 Query: 368 LNISQVVARKMIENKTHGAIVNISSQASKAALKDHT--IYSASKAALDALTRAMALELGP 541 S M E + G+IVNI S + + Y+ASKAA+ LT+++A E GP Sbjct: 124 WACSLAAGAHMRERGS-GSIVNIGSMSGLIVNRPQMQPAYNASKAAVHHLTKSLAAEWGP 182 Query: 542 YGIRVNAINPTVIMTEMAKV 601 GIRVNA+ P TEMA V Sbjct: 183 LGIRVNALAPGYCKTEMAPV 202 >UniRef50_Q825Y8 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 259 Score = 87.8 bits (208), Expect = 2e-16 Identities = 66/192 (34%), Positives = 100/192 (52%), Gaps = 6/192 (3%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSH-LESLQSEYPSIDIVDV 211 M +G+ +VT L AGA +VA SRT S L+ L E S+ V V Sbjct: 1 MSKELEGRTAVVTGASKGIGLAVVQALAGAGAQVVAGSRTTSEGLDGLVEE-GSVTWVPV 59 Query: 212 DIGDWEKTRKVVESLG-HFDALVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 382 D+ + E ++V + G D LVNN A FL + ++ +T D+N+ + +++ Sbjct: 60 DLAEPEGAGRLVGAAGGRIDILVNNVGSAPARTGGFLSVTDEDWHRTVDLNLLTAVRVTR 119 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTI--YSASKAALDALTRAMALELGPYGIRV 556 M+E G++V ISS A L D + YSASKAAL A ++A++ E+GP GIRV Sbjct: 120 AALPLMLE-AGQGSVVTISSV--NATLPDPLVIDYSASKAALVAFSKALSKEVGPKGIRV 176 Query: 557 NAINPTVIMTEM 592 N ++P + TE+ Sbjct: 177 NTVSPGPVETEL 188 >UniRef50_P71079 Cluster: Unidentfied dehydrogenase; n=23; Bacillales|Rep: Unidentfied dehydrogenase - Bacillus subtilis Length = 250 Score = 87.8 bits (208), Expect = 2e-16 Identities = 50/124 (40%), Positives = 75/124 (60%) Frame = +2 Query: 227 EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIE 406 E +++ E+ G D VNNAA V P ++ +++D T ++N KA+L +Q A K++E Sbjct: 71 EMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQEAA-KLME 129 Query: 407 NKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT 586 G IV+ISS S L+++T SKAAL+ALTR +A+EL P I VNA++ I T Sbjct: 130 KNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSGGAIDT 189 Query: 587 EMAK 598 + K Sbjct: 190 DALK 193 >UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 259 Score = 87.8 bits (208), Expect = 2e-16 Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 7/183 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIV---ALSRTRSHLESLQSEYPSIDIVDVDIGD 223 GKR LVT EL R GA++ A + + ++ V D+ Sbjct: 6 GKRALVTGAGMGIGQAIAVELARCGADVAVHYAHTPPDETVGEVERAGRRAHPVRGDLSR 65 Query: 224 WEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 + +VVE +LG D LVNNA + FLD +D FD+N+K ++ Sbjct: 66 VPECERVVEEAAEALGGLDVLVNNAGITRALDFLDTDEETYDAIFDLNMKGYFFCARSAV 125 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 M+E G+IVNI+S A HT Y+A+K A+ A TR +A+EL GIRVNAI P Sbjct: 126 PHMLE-AGGGSIVNITSVHGFAGFPHHTAYAATKGAIIAFTRQLAIELAGRGIRVNAIGP 184 Query: 572 TVI 580 +I Sbjct: 185 GLI 187 >UniRef50_A6PU89 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Victivallis vadensis ATCC BAA-548|Rep: Short-chain dehydrogenase/reductase SDR - Victivallis vadensis ATCC BAA-548 Length = 237 Score = 87.8 bits (208), Expect = 2e-16 Identities = 55/184 (29%), Positives = 89/184 (48%), Gaps = 1/184 (0%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIG 220 +S +GK+I++T L AG + + R L E + + DI Sbjct: 1 MSIEGKKIIITGGATGYGYGDARALKAAGGEVWIVGRRLERLRKAAEEL-GVRFIQGDIT 59 Query: 221 DWEKTRKVVESLGHFDALVNNAAVAV-CEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 E +++E++G D LVNNA +AV EP L S ++ + N+ + + VA K Sbjct: 60 RGEDWDRIMETVGEVDILVNNAGIAVKVEPLLSFSDEEIFRSINGNLTGAILGCRRVAEK 119 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 M+ K+ G I+N++S S Y+A+KA LD +RA+ EL P+ +RV + P+ Sbjct: 120 MVARKS-GLIINVTSVCSHYGWPGFACYTAAKAGLDMFSRALYTELRPHNVRVTVLTPSW 178 Query: 578 IMTE 589 TE Sbjct: 179 GATE 182 >UniRef50_A0TC55 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia ambifaria MC40-6 Length = 260 Score = 87.8 bits (208), Expect = 2e-16 Identities = 47/129 (36%), Positives = 70/129 (54%) Frame = +2 Query: 236 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 R V++ G D L +NA + FLD PS ++T VN+ ++Q VAR+M E T Sbjct: 82 RHAVDAFGKVDVLASNAGICPFHAFLDMPPSVLERTIGVNLNGAFYVTQAVARQMKEQGT 141 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA 595 GAIV SS ++ T Y+ +KA + +L ++ A+ LGPYGIR N++ P I T++ Sbjct: 142 GGAIVATSSISALVGGGMQTHYTPTKAGVHSLMQSCAIALGPYGIRCNSVMPGTIATDLN 201 Query: 596 KVGWSDPIK 622 D K Sbjct: 202 AADLEDEDK 210 >UniRef50_Q6ADW8 Cluster: Oxidoreductase; n=3; Actinomycetales|Rep: Oxidoreductase - Leifsonia xyli subsp. xyli Length = 264 Score = 87.4 bits (207), Expect = 3e-16 Identities = 64/205 (31%), Positives = 96/205 (46%), Gaps = 9/205 (4%) Frame = +2 Query: 29 LKMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD 208 + ME++ +GK LVT L G +V +RT + SE + + Sbjct: 1 MDMELTLRGKTALVTGASRGIGLATARTLVAEGVRVVGAART---ITPELSEAAPLSVAG 57 Query: 209 VDIGDWEKTRKVVE----SLGHFDALVNNAAVAVCEP-----FLDCSPSNFDKTFDVNVK 361 D+ + R+VVE LG FD LVNN + FLD + + D+N+ Sbjct: 58 -DLSTPDGARRVVEVALSELGGFDILVNNVGAGDADKLKPGGFLDADDAQWRNLLDLNLF 116 Query: 362 AVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGP 541 + + S+ +IE HGAIVN+SS S+ YS +KAAL A + +A E GP Sbjct: 117 SAVWTSRAALPSLIER--HGAIVNVSSITSRVPATGPVGYSEAKAALTAFGKRLAEEFGP 174 Query: 542 YGIRVNAINPTVIMTEMAKVGWSDP 616 G+RVN ++P+ + T + W DP Sbjct: 175 QGVRVNTVSPSPVGTGL----WRDP 195 >UniRef50_Q5YUD9 Cluster: Putative short chain dehydrogenase; n=1; Nocardia farcinica|Rep: Putative short chain dehydrogenase - Nocardia farcinica Length = 249 Score = 87.4 bits (207), Expect = 3e-16 Identities = 64/186 (34%), Positives = 89/186 (47%), Gaps = 6/186 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD-VDI---G 220 GK +LVT L GA +VA + +E++ +E P+ + +D+ G Sbjct: 13 GKVVLVTGAGRGQGAEHTRRLAELGARVVAADLDVARVEAIVAELPTAAVATALDVRRAG 72 Query: 221 DWEKTRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVN-VKAVLNISQVVAR 394 DW +V E G D LVNNA VA P + S DV+ + A+L + V+ Sbjct: 73 DWSAAVDLVRERFGRLDVLVNNAGVAPRAPLSELSEEELRFVLDVDLIGAILGMRAVLP- 131 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 + + G+IVNI+S A Y+A+K L TR+ A ELGP GIRVNAI P Sbjct: 132 --LMREHGGSIVNIASTAGMTGYAGGLAYAAAKWGLRGATRSAAKELGPLGIRVNAICPG 189 Query: 575 VIMTEM 592 I T M Sbjct: 190 AIDTAM 195 >UniRef50_Q6W1M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Bacteria|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Rhizobium sp. (strain NGR234) Length = 272 Score = 87.4 bits (207), Expect = 3e-16 Identities = 49/126 (38%), Positives = 65/126 (51%) Frame = +2 Query: 242 VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHG 421 ++E+ A VNNA F D S +++ DVN+ Q++AR MIE KT G Sbjct: 76 LIEAFRGVAAFVNNAGTLALASFTDISLADWRGVIDVNLTGSFLAGQLIARHMIETKTPG 135 Query: 422 AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKV 601 IVN+SS L Y SKA + LT+ MAL+L P+GIRVNA+ P T M V Sbjct: 136 RIVNVSSVHEAVPLLGGAAYCTSKAGIGMLTKCMALDLAPHGIRVNAVGPGETATPMIGV 195 Query: 602 GWSDPI 619 + I Sbjct: 196 AEGEDI 201 >UniRef50_Q1VSS0 Cluster: Gluconate 5-dehydrogenase, putative; n=1; Psychroflexus torquis ATCC 700755|Rep: Gluconate 5-dehydrogenase, putative - Psychroflexus torquis ATCC 700755 Length = 251 Score = 87.4 bits (207), Expect = 3e-16 Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 6/204 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP--SIDIVDVDI 217 + KG+ IL++ + GA ++ L R LE ++S+ + + VD+ Sbjct: 6 TLKGRTILISGASSGIGEATAIVCDQLGATLLLLGRNEVRLEEVKSKLSLGAHKSLVVDL 65 Query: 218 GDWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 D+E +V+ ES G LVN A V PF P + +NV A +S++ Sbjct: 66 SDFEVLEQVLKPFLESTGAIHGLVNAAGVTSTFPFKLFKPEKLEGLLKINVHAAFYLSKL 125 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 + +KM +K+ G+IV ISS + K T+Y+ SK A+ A ++MA+EL GIRVN++ Sbjct: 126 MLKKM--SKSGGSIVFISSIMATHGEKAKTLYAISKGAVSAGVKSMAIELAAKGIRVNSV 183 Query: 566 NPTVIMTEMAKVGWSDPIKANEML 637 P ++ T M S K NE L Sbjct: 184 APGIVNTPMTA---SATYKKNEEL 204 >UniRef50_Q1RS55 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=1; Bacillus amyloliquefaciens|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Bacillus amyloliquefaciens Length = 245 Score = 87.4 bits (207), Expect = 3e-16 Identities = 46/120 (38%), Positives = 74/120 (61%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 +V D LVNNA + + + + + D+ ++N+ +V+ +++ V+R M++ + Sbjct: 74 QVYRKFSRIDGLVNNAGLNLDQLLPLTNDEDIDRILNLNIGSVIKLTRNVSRVMLKQNS- 132 Query: 419 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 G+IVNISS K ++YSASKAALD LTR++A ELG GIRVN++ P + T+M K Sbjct: 133 GSIVNISSIIGSRGFKGTSVYSASKAALDGLTRSLARELGSKGIRVNSLAPGFVDTDMTK 192 >UniRef50_Q1M6K9 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative short-chain dehydrogenase/reductase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 251 Score = 87.4 bits (207), Expect = 3e-16 Identities = 56/197 (28%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS---IDIVDVDI 217 F+GK +LVT L GA ++A+ T + + E ++ + +D+ Sbjct: 4 FEGKVVLVTGAGSGIGAATVKRLHAEGATVIAVDVTEEGVSKVVQEIGDRTRVEGLALDV 63 Query: 218 GDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 D + + V + G LVN A + +D P +F + VN++ +N+ Q Sbjct: 64 CDHSASIETVADVRKRHGALHGLVNCAGIKGVGSIVDVKPESFGRVMAVNLEGTINLCQA 123 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 + + ++ AIVNISS A + + Y ASK A+ +T++M+ ELGP GIRVNA+ Sbjct: 124 FVQAVKDDTGDRAIVNISSGAGVMGVANRLPYVASKFAVSGITKSMSPELGPLGIRVNAV 183 Query: 566 NPTVIMTEMAKVGWSDP 616 P + T + DP Sbjct: 184 APGMTKTPFTEYMLQDP 200 >UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family precursor; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Oxidoreductase, short chain dehydrogenase/reductase family precursor - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 252 Score = 87.4 bits (207), Expect = 3e-16 Identities = 65/192 (33%), Positives = 98/192 (51%), Gaps = 8/192 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHL-ESLQ------SEYPSID 199 + KGK ++T L GA +V + R L E++ E +I Sbjct: 1 MKLKGKVAVITGGGTGIGRAAAIALAAEGARVVVMGRRPEPLNETVDIVKERGGEGLAIP 60 Query: 200 IVDVDIGDWEKTR-KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 I D EK R +V E+ G D LVNNA A+ +PF+ S +FD+ + V++++V + Sbjct: 61 SDVTKIEDIEKARDEVRETYGRLDILVNNAGSALFKPFMKTSLEDFDRIYQVDLRSVFAV 120 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 SQ++ M+E G+I+NI+S K + Y A K + LTRA+A ELGP IRV Sbjct: 121 SQLMLPLMLEG-GGGSIINIASILGVLGGKSSSAYCAMKGGVVQLTRALAAELGP-EIRV 178 Query: 557 NAINPTVIMTEM 592 N + P+ I+T M Sbjct: 179 NCLCPSHIITPM 190 >UniRef50_A6EBP7 Cluster: Short chain dehydrogenase; n=1; Pedobacter sp. BAL39|Rep: Short chain dehydrogenase - Pedobacter sp. BAL39 Length = 269 Score = 87.4 bits (207), Expect = 3e-16 Identities = 54/188 (28%), Positives = 94/188 (50%), Gaps = 7/188 (3%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS---IDIVDVDIG 220 K K I +T + +AGA +V +S L+ + +YP + + D+ + Sbjct: 5 KDKVIFITGGSRGIGLECAHKYKKAGARVVIISNDPKSLDKCRKDYPEPHHLILCDISVA 64 Query: 221 DWEKTRKVVESL---GHFDALVNNAAVA-VCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 + + E+L G D + NNA +A +P + + + F+VN+K V + ++ Sbjct: 65 S-DVEHAIAETLNKYGRIDVIHNNAGIAHPSKPIHETTDEEWTALFNVNLKGVYHTTKFG 123 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 + T G ++N SS + +DH Y+A+K A++ALT++MAL+ Y IRVNA+ Sbjct: 124 IEAL--KVTQGCVLNTSSLVGEIGQEDHAAYAATKGAINALTKSMALDYAKYKIRVNAVA 181 Query: 569 PTVIMTEM 592 P + TEM Sbjct: 182 PAGVWTEM 189 >UniRef50_A1SPY4 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 279 Score = 87.4 bits (207), Expect = 3e-16 Identities = 63/204 (30%), Positives = 107/204 (52%), Gaps = 10/204 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS--IDIVDV--DI 217 KGK ++++ E + GA++V SRT + L LQ E + +V V D+ Sbjct: 25 KGKVVVISGIGPGLGRSLAEEAAKMGADLVIASRTEARLVELQGELEGHGVKVVSVVTDV 84 Query: 218 GDWEKTR-----KVVESLGHFDALVNNA-AVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D E +R + +E+ G D ++NNA A+ +P P K + NV A L +S Sbjct: 85 TD-EDSRVNLRDRALEAFGRVDCVINNAFAIPPMDPITRIDPRKLAKVNETNVFAPLRLS 143 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + A + E++ G+I+ ++S S ++ ++ Y SK AL+ L ++A ELGP GIRVN Sbjct: 144 ALFADALAESR--GSIIMLNSCVSFSSQPEYAGYKLSKGALEHLASSLATELGPRGIRVN 201 Query: 560 AINPTVIMTEMAKVGWSDPIKANE 631 ++ P+ I ++ + G+ D + A E Sbjct: 202 SVAPSYIYEDVNR-GYFDFLAAVE 224 >UniRef50_P0A9Q0 Cluster: Gluconate 5-dehydrogenase; n=12; Gammaproteobacteria|Rep: Gluconate 5-dehydrogenase - Escherichia coli O6 Length = 254 Score = 87.4 bits (207), Expect = 3e-16 Identities = 61/194 (31%), Positives = 87/194 (44%), Gaps = 9/194 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVA---------LSRTRSHLESLQSEYPSI 196 S GK IL+T L + GA I+ L+ + H E +Q+ Sbjct: 6 SLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPF 65 Query: 197 DIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 ++ D + + +G D LVNNA + PF + ++ VN AV + Sbjct: 66 NVTHKHEID-AAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLV 124 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 SQ V R M+E K G ++NI S S+ T Y+ASK A+ LTR M +EL + I+V Sbjct: 125 SQAVTRHMVERKA-GKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQV 183 Query: 557 NAINPTVIMTEMAK 598 N I P TEM K Sbjct: 184 NGIAPGYFKTEMTK 197 >UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin2083 protein - Listeria innocua Length = 263 Score = 87.0 bits (206), Expect = 3e-16 Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 8/192 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD-----VD 214 K K +L+T ++ +G N++ +R+ L LQ + V+ +D Sbjct: 6 KNKTVLITGASNGLGAEIARQVAASGGNVIITARSTEKLLDLQKDIHDNFSVEATYFTLD 65 Query: 215 IGDWEKTRKVVESLG---HFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + D+E+ ++V + D LVN A + E +D +K FD NV ++ ++Q+ Sbjct: 66 MTDFEQVKQVSAEINASYQIDVLVNCAGFGLFENAVDIPFETIEKMFDTNVLGLIQLTQL 125 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 + +M K G I+NI+SQA+K A T+YSA+K A+ + A+ LEL P I V I Sbjct: 126 ILPQMQARKA-GHIINIASQAAKIATPKSTVYSATKYAVLGFSNALRLELMPDKIHVTTI 184 Query: 566 NPTVIMTEMAKV 601 NP I T V Sbjct: 185 NPGPIATNFFDV 196 >UniRef50_Q7WBP3 Cluster: Probable short chain dehydrogenase; n=2; Bordetella|Rep: Probable short chain dehydrogenase - Bordetella parapertussis Length = 249 Score = 87.0 bits (206), Expect = 3e-16 Identities = 61/173 (35%), Positives = 88/173 (50%), Gaps = 5/173 (2%) Frame = +2 Query: 137 VALSRTRSHLESLQSEYPSIDIVDVDIGDWEK----TRKVVESLGHFDALVNNAAVAVCE 304 + L+ R E+L++E ++D+ D + R+V E LG LVNNA V Sbjct: 37 IDLAGARRTAEALRAEGARAAAYELDVRDAARCAAVARQVGEDLGALGVLVNNAGVRPRH 96 Query: 305 PFL-DCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIY 481 F D + + + DVNV V N++ + T GA+VNI+S A+ A Y Sbjct: 97 AFDGDERDALWRQAMDVNVDGVRNMTLACLEGLAA--TRGAVVNITSIAASRASAQSIAY 154 Query: 482 SASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKANEMLS 640 S SKAA LT+ +ALEL P GIRVNA+ P VI T M + DP + +++ Sbjct: 155 STSKAAAQMLTKVLALELAPCGIRVNAVAPGVIETAMTQSSRDDPQRRGALMA 207 >UniRef50_Q53W85 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=2; Thermus thermophilus|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 234 Score = 87.0 bits (206), Expect = 3e-16 Identities = 58/182 (31%), Positives = 89/182 (48%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIG 220 + KGK+ LV R GA ++ + H E LQ P++ + D Sbjct: 1 MKLKGKKALVIAAGQGIGRAIAEAFQREGAEVLGATL---HPEKLQGVVPAVRL---DAR 54 Query: 221 DWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 D E +++ L D LVN V L+ + ++++ F +N K+V Q KM Sbjct: 55 DKEAVFHLIQGLDRLDVLVNAQGVVPVGGLLEATDQDWEEAFLLNAKSVFWAMQAALPKM 114 Query: 401 IENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVI 580 + G+++NI+S A+ + IYSA+KAAL A+T+A ALE P G+RVNAI P + Sbjct: 115 AA-QGGGSVINIASVAAFKMVPGRFIYSATKAALVAMTKAAALEFAPKGVRVNAICPGTV 173 Query: 581 MT 586 T Sbjct: 174 DT 175 >UniRef50_Q3WJB3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 203 Score = 87.0 bits (206), Expect = 3e-16 Identities = 46/110 (41%), Positives = 64/110 (58%) Frame = +2 Query: 257 GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNI 436 G D LVNNA + L FD+ + VNVKA ++Q VA M+ G I+N+ Sbjct: 82 GRLDILVNNAGIFPPNTTLTTDDRTFDQVYAVNVKAPFFLTQAVAPAMVA-AGEGVIINL 140 Query: 437 SSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT 586 S ++ L ++YS++K AL+ LTRA A E GP G+RVNA++P VI T Sbjct: 141 GSWVARLGLPVGSLYSSTKGALETLTRAWAAEFGPLGVRVNAVSPGVIRT 190 >UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Erythrobacter sp. NAP1 Length = 267 Score = 87.0 bits (206), Expect = 3e-16 Identities = 63/205 (30%), Positives = 95/205 (46%), Gaps = 8/205 (3%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHL----ESLQSEYPSIDIVDVD 214 F GK +++T GAN+V +R ++L ++ DV Sbjct: 7 FAGKTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADTLDADRTLTCPGDVS 66 Query: 215 IGDW--EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 D+ E K VE G D LVNNA V D+ D+NVK V+ + + Sbjct: 67 SSDFANEIVAKTVERFGGLDCLVNNAGVGGSSMLHKTDDEEIDRIIDINVKGVIYLCRAA 126 Query: 389 ARKMIENKT--HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 + +++ G+I+NISS + IY+ASK A+ LTR +A ++G GIRVNA Sbjct: 127 IPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTRGLAQQIGGMGIRVNA 186 Query: 563 INPTVIMTEMAKVGWSDPIKANEML 637 INP++ ++M D I AN+ L Sbjct: 187 INPSITRSDMV-----DGILANDAL 206 >UniRef50_A3PW05 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Corynebacterineae|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 256 Score = 87.0 bits (206), Expect = 3e-16 Identities = 54/163 (33%), Positives = 85/163 (52%), Gaps = 1/163 (0%) Frame = +2 Query: 140 ALSRTRSHLESLQSEYPSIDIVDVDIGDWEK-TRKVVESLGHFDALVNNAAVAVCEPFLD 316 A R HL L ++ + DI E + VE G D LVNNAA A+ +P + Sbjct: 50 AYERAAEHLRGLGAQAVGVPTHLGDIDSLESLVNRTVEEFGGIDILVNNAANALAQPLGE 109 Query: 317 CSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKA 496 +P + K++DVN++ + + Q A ++ H A++N S + + ++Y+A KA Sbjct: 110 MTPEAWTKSYDVNLRGPVFLVQH-ALPHLKASAHAAVLNTVSVGAFNFAPNVSMYAAGKA 168 Query: 497 ALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKA 625 AL + TR+MA PYGIRVNA+ P + T+M + + I A Sbjct: 169 ALLSFTRSMAAAYAPYGIRVNALAPGPVDTDMMRNNSQEAIDA 211 >UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family protein; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 249 Score = 87.0 bits (206), Expect = 3e-16 Identities = 57/204 (27%), Positives = 95/204 (46%), Gaps = 10/204 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID-----IV 205 +S KGK I++T L + G N+V +R L+ L+S+ + ++ Sbjct: 1 MSMKGKTIIITGASSGIGEATAMRLAKEGVNVVLTARREEKLKELKSKIDKENGGKALVI 60 Query: 206 DVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 D+ E + +++ G D L+NNA + + +DK DVN+K VLN Sbjct: 61 PGDVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLN 120 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGP-YGI 550 V M+E K+ G I+NISS A++ +Y A+K+A+ + + EL P + I Sbjct: 121 GVAAVLPTMMEQKS-GNIINISSSAARKIYPGGAVYCATKSAVKMFSEGLRQELAPKFNI 179 Query: 551 RVNAINPTVIMTEMAKVGWSDPIK 622 + +I P + TE+ D IK Sbjct: 180 NITSIEPGFVDTELTDTITDDEIK 203 >UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=23; Bacteria|Rep: Uncharacterized oxidoreductase ygcW - Escherichia coli (strain K12) Length = 261 Score = 87.0 bits (206), Expect = 3e-16 Identities = 64/198 (32%), Positives = 93/198 (46%), Gaps = 7/198 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES---LQSEYPSIDIVDVD 214 S KGK +VT L +AGANI S + + E+ ++ + +D + V Sbjct: 15 SLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVG 74 Query: 215 IGDWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 I +K++ E G D LVNNA + LD +++D DVN+ A +S Sbjct: 75 ITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSY 134 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 A+ MI K+ G I+NI S S + YSA+K AL T+A ELG Y I+VN Sbjct: 135 EAAKIMIPQKS-GKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNG 193 Query: 563 INPTVIMTEMAKVGWSDP 616 I P T++ S+P Sbjct: 194 IAPGYYATDITLATRSNP 211 >UniRef50_UPI000023E6B9 Cluster: hypothetical protein FG02829.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG02829.1 - Gibberella zeae PH-1 Length = 264 Score = 86.6 bits (205), Expect = 4e-16 Identities = 64/202 (31%), Positives = 94/202 (46%), Gaps = 8/202 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPSIDIVDV 211 S GK ++T L RAG IV ++R L+ L + + + + Sbjct: 17 SLAGKVAVITGGSSGIGREMAIALGRAGCRIVLIARRPKPLQDTIDHLADLHVTAEAIVA 76 Query: 212 DIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+G+ R ++++ G D L+N AAV D S +D+T VN+ A + Sbjct: 77 DLGNPASVRDAIQAIKATVGSPDILINAAAVNYRPHMNDLSQGAWDETIAVNLTAPFALG 136 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 Q KM EN G I+NI SQ + + Y ASKA L LTR+ A +G+ N Sbjct: 137 QAFGPKMAENGW-GRIINIISQQAFRCYGNSGAYGASKAGLLGLTRSQAEAWSRHGVLCN 195 Query: 560 AINPTVIMTEMAKVGWSDPIKA 625 AI P V+ T M +V ++DP KA Sbjct: 196 AIAPGVVDTPMTRVAFNDPAKA 217 >UniRef50_Q2K0D6 Cluster: Probable oxidoreductase protein, dehydrogenase/reductase SDR family; n=2; Rhizobium|Rep: Probable oxidoreductase protein, dehydrogenase/reductase SDR family - Rhizobium etli (strain CFN 42 / ATCC 51251) Length = 256 Score = 86.6 bits (205), Expect = 4e-16 Identities = 65/201 (32%), Positives = 95/201 (47%), Gaps = 8/201 (3%) Frame = +2 Query: 38 EISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDIV 205 + S GK LVT AG++IV R + L +E I V Sbjct: 7 DFSLDGKVTLVTGASRGIGRACALACAAAGSDIVLGVRNVAASADLVAELEGAGRKILAV 66 Query: 206 DVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 ++DI + + V++ D LVNN VA + D+ DVN+K Sbjct: 67 ELDIPNKAHIAQAVDAALTTFDRIDVLVNNVGVAPGNLAELVEEKDLDEILDVNIKGTFL 126 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 ++Q V R+MI+ + G I++ISSQA+ AL+ IY SKAA++ LTR +A E Y + Sbjct: 127 MTQAVGRQMIK-QNGGRIISISSQAATVALRGEAIYCMSKAAINHLTRCLAAEWARYNVT 185 Query: 554 VNAINPTVIMTEMAKVGWSDP 616 VN ++PT I T+ SDP Sbjct: 186 VNTVSPTFIHTDGTAPFLSDP 206 >UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentisphaera araneosa HTCC2155|Rep: Glucose-1-dehydrogenase - Lentisphaera araneosa HTCC2155 Length = 264 Score = 86.6 bits (205), Expect = 4e-16 Identities = 46/129 (35%), Positives = 73/129 (56%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 K +E G D +VNNA + +PFL+ + ++DK + N++AV Q + + I+N+T Sbjct: 72 KAIEKWGRVDCIVNNAGINFAKPFLETTKQDWDKVLNTNLRAVFFFMQKLCKYWIDNQTK 131 Query: 419 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 G+IVNISS ++A L Y+A+K L + + EL GIRVN ++P + T + Sbjct: 132 GSIVNISSVHNQATLPGAGPYAATKNGLLGIMKCAVNELSSKGIRVNTVSPGLCNTNI-- 189 Query: 599 VGWSDPIKA 625 W D I+A Sbjct: 190 --WQDIIEA 196 >UniRef50_Q01JQ2 Cluster: H0523F07.11 protein; n=4; Oryza sativa|Rep: H0523F07.11 protein - Oryza sativa (Rice) Length = 295 Score = 86.6 bits (205), Expect = 4e-16 Identities = 54/154 (35%), Positives = 80/154 (51%), Gaps = 4/154 (2%) Frame = +2 Query: 122 AGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVV----ESLGHFDALVNNAA 289 AG +VA +R+R+ + L+ + P ++++D+ E R V LG D LVNNA Sbjct: 48 AGCAVVATARSRASMRGLEGD-PRYLLLELDVRSDESARAAVADAVRELGRVDVLVNNAG 106 Query: 290 VAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKD 469 V + P + F + FD NV + + V +MIE + G IVN+ S + A Sbjct: 107 VHLVAPLAEVPMEEFQQVFDTNVYGAMRLIHAVIPQMIE-REQGTIVNVGSITALAPGPW 165 Query: 470 HTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 +YSASKAAL AL+ + LEL +GI V + P Sbjct: 166 AGVYSASKAALHALSDTLRLELKSFGINVMIVAP 199 >UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3alpha-reductase - Spodoptera littoralis (Egyptian cotton leafworm) Length = 249 Score = 86.6 bits (205), Expect = 4e-16 Identities = 61/196 (31%), Positives = 100/196 (51%), Gaps = 13/196 (6%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP----SIDIVDVD 214 F K +LVT + GA++ + R ++ L+ ++S +I + D Sbjct: 2 FANKVVLVTGGSSGIGAATVEAFVKEGASVAFVGRNQAKLKEVESRCQQHGANILAIKAD 61 Query: 215 IGDWEKTR----KVVESLGHFDALVNNAAV----AVCEPFLDCSPSNFDKTFDVNVKAVL 370 + E+ + + V+ G D LVNNA + +V EP L FD+T + N++ V+ Sbjct: 62 VSKDEEAKIIVQQTVDKFGKLDVLVNNAGILRFASVLEPTLI---QTFDETMNTNLRPVV 118 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAA-LKDHTIYSASKAALDALTRAMALELGPYG 547 I+ + +I K G+IVN+SS S + YS SKAA+D T+ ALEL P G Sbjct: 119 LITSLAIPHLIATK--GSIVNVSSILSTIVRIPGIMSYSVSKAAMDHFTKLAALELAPSG 176 Query: 548 IRVNAINPTVIMTEMA 595 +RVN++NP ++T++A Sbjct: 177 VRVNSVNPGPVLTDIA 192 >UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Nitrosopumilus maritimus SCM1 Length = 269 Score = 86.6 bits (205), Expect = 4e-16 Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 7/193 (3%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIG 220 +S GK LVT L GAN+ + + LE + SE + + D+ Sbjct: 23 LSLSGKVALVTGGSRGIGFATAKVLSENGANVAITGKVQERLEKVSSEISNSFAIVADVR 82 Query: 221 DWEKTR----KVVESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 E + K+VE G D LVNNA V + + +++ DVN+ +++ Sbjct: 83 KTEDVKNAIKKIVEKFGRLDILVNNAGVFPKIKKLHEIDDEEWNEVLDVNLTGQFRVTKE 142 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTI--YSASKAALDALTRAMALELGPYGIRVN 559 + KT G+I+NISS A A + YSA+KAAL LT+ ALE IRVN Sbjct: 143 AIPHL--QKTSGSIINISSDAGLKAYQGFNADAYSATKAALIVLTKCWALEYSKDKIRVN 200 Query: 560 AINPTVIMTEMAK 598 I P V+ T+M K Sbjct: 201 CICPGVVDTDMTK 213 >UniRef50_P50199 Cluster: Gluconate 5-dehydrogenase; n=35; Bacteria|Rep: Gluconate 5-dehydrogenase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 256 Score = 86.6 bits (205), Expect = 4e-16 Identities = 61/194 (31%), Positives = 88/194 (45%), Gaps = 9/194 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS---------I 196 S G R LVT L R GA +V R L+S QS + + Sbjct: 8 SLSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVF 67 Query: 197 DIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 D+ D D + + +G D L+NNA + P + S ++D NV AV + Sbjct: 68 DVTDQD-AVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAVFFV 126 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 Q VAR MI + G IVNI S S+ A Y+A+K A+ LT+ MA + G +G+++ Sbjct: 127 GQAVARHMIP-RGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGLQI 185 Query: 557 NAINPTVIMTEMAK 598 N + P TEM + Sbjct: 186 NGLAPGYFATEMTE 199 >UniRef50_Q89V28 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=4; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Bradyrhizobium japonicum Length = 243 Score = 86.2 bits (204), Expect = 6e-16 Identities = 68/195 (34%), Positives = 90/195 (46%), Gaps = 9/195 (4%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTR-SHLESLQSEYPSID---- 199 M KG+ LVT L AGA + R R E L E Sbjct: 1 MANDLKGRTALVTGGSRGIGAAVCRLLAEAGAAVAINCRERIGQAEQLAGEINKRGGRAI 60 Query: 200 IVDVDIGDWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAV 367 V D+ E +V LG D LVNNA +A+ D + +FD+T VN+K+V Sbjct: 61 AVAADVSQREAVAAMVARVTAELGPIDILVNNAGIAITRGVDDLTEDDFDRTILVNLKSV 120 Query: 368 LNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 547 +Q V M +K G IVNISS A++ A Y+ASKA ++ LTR A L G Sbjct: 121 FLCTQAVLPAM-RSKKWGRIVNISSGAARGAGSIGPHYNASKAGMEGLTRGYAARLVKDG 179 Query: 548 IRVNAINPTVIMTEM 592 I VNA+ P++I T+M Sbjct: 180 INVNAVAPSLIETDM 194 >UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 249 Score = 86.2 bits (204), Expect = 6e-16 Identities = 58/204 (28%), Positives = 98/204 (48%), Gaps = 8/204 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE--SLQSEYPSIDIVDV--DIG 220 GK +VT + GA +V +R + E +LQ +++ + D+G Sbjct: 6 GKVGIVTGGSKGIGFATAKRIAEEGAKVVIANRNKEEGEKAALQLREKGLEVYSIPCDVG 65 Query: 221 DWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 +K+V + G D LVN A V V +P + + +++ D+N+K Sbjct: 66 KVADIKKLVSEVYGRYGRIDILVNCAGVNVRKPIEEYTEEDWNYMVDINLKGTFFACIEA 125 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 + MI K G IVN++S ++ L + IY+ +K + LT+A+A+E Y IRVNA++ Sbjct: 126 GKHMIAQK-EGVIVNLASIQAEEVLPERGIYATTKGGVKQLTKALAVEWAKYNIRVNAVS 184 Query: 569 PTVIMTEMAKVGWSDPIKANEMLS 640 P I TEM + DP N +++ Sbjct: 185 PAFIKTEMVEKVLQDPYWGNLIIN 208 >UniRef50_Q74T42 Cluster: Gluconate 5-dehydrogenase; n=17; Gammaproteobacteria|Rep: Gluconate 5-dehydrogenase - Yersinia pestis Length = 289 Score = 86.2 bits (204), Expect = 6e-16 Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 8/206 (3%) Frame = +2 Query: 5 FFSGHSV*LKMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSE 184 ++ V +K S + +++L+T L GA I+ T E +E Sbjct: 28 YYRYQEVTMKNLFSLENRKVLITGSAQGIGFLLAKGLAEFGAEIIINDITAERAEKAVAE 87 Query: 185 YPSIDIVD----VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDK 340 + + ++ + ++ + +E + G D L+NNA + F + ++D Sbjct: 88 LRASGFIAHAAAFNVTNHDEVNEAIEKIESHIGAIDVLINNAGIQRRHAFTEFPEKDWDD 147 Query: 341 TFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRA 520 VN K+V +SQ VAR M++ + G I+NI S S+ T Y+ASK A+ LTR Sbjct: 148 VIAVNQKSVFLVSQAVARYMVKRQ-RGKIINICSMQSELGRDTITPYAASKGAVKMLTRG 206 Query: 521 MALELGPYGIRVNAINPTVIMTEMAK 598 M +EL Y I+VN I P T+M K Sbjct: 207 MCVELARYNIQVNGIAPGYFKTDMTK 232 >UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; gamma proteobacterium HTCC2207|Rep: Short-chain dehydrogenase/reductase SDR - gamma proteobacterium HTCC2207 Length = 255 Score = 86.2 bits (204), Expect = 6e-16 Identities = 63/209 (30%), Positives = 95/209 (45%), Gaps = 8/209 (3%) Frame = +2 Query: 38 EISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IV 205 E GK +VT L GA +V +R LE+L +E + V Sbjct: 4 EFDMSGKVAMVTGASSGFGVNFAKILAARGAKVVVAARRVDRLEALVAEIQAAGGEACAV 63 Query: 206 DVDIGDWEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 +D+ E + + G + NNA VA + L +++D D N+K V Sbjct: 64 AMDVTSAESVTAAFDKGEAAFGTITVVSNNAGVADGKSALKADEASWDWVVDTNLKGVWM 123 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 ++Q A++M+ G+IVN +S ++YSASKA + LT+A ALE G GIR Sbjct: 124 VAQEAAKRMVAAGVGGSIVNTASILGLRVAFAQSVYSASKAGVIQLTKAQALEWGRKGIR 183 Query: 554 VNAINPTVIMTEMAKVGWSDPIKANEMLS 640 VNA+ P +TEM + + P A + S Sbjct: 184 VNALCPGYFLTEMTESLFDSPESAKFLAS 212 >UniRef50_A6UKV7 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 241 Score = 86.2 bits (204), Expect = 6e-16 Identities = 54/196 (27%), Positives = 100/196 (51%), Gaps = 6/196 (3%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKT 235 K +++T G ++VA SR S S ++++D DIGD + Sbjct: 5 KTVVITGASQGIGAGLVKTFLDKGWSVVATSRRISEATSFDRA-GRLELIDGDIGDPKTA 63 Query: 236 RKV----VESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 403 +V VE G DALVNNA V +PFL+ + +F + N++ ++ ++ R+M+ Sbjct: 64 ERVSQVAVEQFGSIDALVNNAGVFFTKPFLEYTIEDFRRLSATNLEGFVHFTKHAVRQML 123 Query: 404 ENKTHGAIVNISSQASKAALK--DHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 ++ G++V I+S + + ++ +K L+A+T+++ALE IRVNA++P V Sbjct: 124 RQRSGGSVVTITSSLTDHPIAGVKASLPMITKGGLNAITKSLALEFASDNIRVNAVSPGV 183 Query: 578 IMTEMAKVGWSDPIKA 625 + T + G D +++ Sbjct: 184 VDTPLHATGSRDYLRS 199 >UniRef50_A4FJJ0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Saccharopolyspora erythraea (strain NRRL 23338) Length = 249 Score = 86.2 bits (204), Expect = 6e-16 Identities = 55/163 (33%), Positives = 85/163 (52%), Gaps = 8/163 (4%) Frame = +2 Query: 122 AGANIVA----LSRTRSHLESLQS----EYPSIDIVDVDIGDWEKTRKVVESLGHFDALV 277 AGA ++ L R +E L+S P++ V D+ D R++ E G L+ Sbjct: 30 AGAGVIITGTDLERGAQVVEDLRSVGGDSAPTVRFVAADLADPAAVRQLAEEAGAVSILI 89 Query: 278 NNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKA 457 NNA+V P + ++D F VNV+A ++ + A KM N G+IVN+SS A+ Sbjct: 90 NNASVVTLGPTTEQDIVSYDAAFAVNVRAPFLLTALFAPKMGANGG-GSIVNVSSTAAGL 148 Query: 458 ALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT 586 + +Y A+KAA+++LTR A E P +RVNA+ P + T Sbjct: 149 GMPGMAVYGATKAAVESLTRTWAAEFAPSNVRVNAVAPGPMRT 191 >UniRef50_A7QCC5 Cluster: Chromosome undetermined scaffold_77, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome undetermined scaffold_77, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 250 Score = 86.2 bits (204), Expect = 6e-16 Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 7/186 (3%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI------DIVDVDI 217 + +L+T E+ + G +V SR++ L SLQSE S+ D + Sbjct: 27 RTVLITGVGKGLGRALALEIAKRGHTVVGCSRSQDRLTSLQSELSSVASSPQSDSARSNS 86 Query: 218 GDWEKTRKVVESLGHFDALVNNAA-VAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 E R V+E G D +VNNA + + FD D NVK N+ + Sbjct: 87 SVEELARAVMEKKGVPDIIVNNAGTINRNNRIWEVPEEEFDTVIDTNVKGTANVMRQFIP 146 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 MIENK G IVN+SS ++A Y ASK A++ L+R++A EL P G+ + A+NP Sbjct: 147 LMIENK-QGIIVNMSSGWGRSAAAQVAPYCASKWAVEGLSRSVAKEL-PSGLAIVALNPG 204 Query: 575 VIMTEM 592 VI T+M Sbjct: 205 VINTDM 210 >UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 402 Score = 86.2 bits (204), Expect = 6e-16 Identities = 62/196 (31%), Positives = 93/196 (47%), Gaps = 16/196 (8%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES-----LQSEYPSIDIVDV 211 F GK LVT + GA + R LE L+S P+ +++ + Sbjct: 126 FSGKVALVTGSSNGIGRAAALLFAQQGAKVTITGRNAERLEETRQAILKSGVPAENVLAI 185 Query: 212 ------DIGDWEKTRKVVESLGHFDALVNNAAVAVCEPF----LDCSPSNFDKTFDVNVK 361 D G + ++ G D LVNNA AV +P +D +FDKTF +N++ Sbjct: 186 AADLATDQGQTDLINGTLQKFGRLDILVNNAGAAVNDPQGRMGIDQQIEDFDKTFQINMR 245 Query: 362 AVLNISQVVARKMIENKTHGAIVNISS-QASKAALKDHTIYSASKAALDALTRAMALELG 538 +V+ + Q +I KT G I+N+SS A D Y SKAALD TR+ A+ L Sbjct: 246 SVVTLVQKAKEHLI--KTKGEIINVSSIGGGPHAQPDMMYYGMSKAALDQFTRSTAITLI 303 Query: 539 PYGIRVNAINPTVIMT 586 +G+RVN+++P + T Sbjct: 304 QHGVRVNSVSPGGVYT 319 Score = 41.5 bits (93), Expect = 0.017 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = +2 Query: 479 YSASKAALDALTRAMALELGPYGIRVNAINPTVIMT 586 Y SKAALD TR+ A+ L +G+RVN+++P V+ T Sbjct: 4 YGMSKAALDQFTRSTAITLIQHGVRVNSVSPGVVYT 39 >UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH; n=4; Proteobacteria|Rep: Subunit of 2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 248 Score = 85.8 bits (203), Expect = 8e-16 Identities = 50/119 (42%), Positives = 70/119 (58%) Frame = +2 Query: 236 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 ++ VE+ G D LVNNA + S +++D T DVN+K +Q V M+ENK Sbjct: 74 QQTVEAFGRIDILVNNAGMERAGALRKLSEADWDITVDVNLKGTFLCTQAVHGHMVENK- 132 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 HG IVNI+S+A T YS++KA + +TRA+A+ELG GI VN + P +I T M Sbjct: 133 HGRIVNIASRAWLGG-AGQTPYSSAKAGVVGMTRALAIELGRSGITVNCVAPGLIHTPM 190 >UniRef50_Q0RYG2 Cluster: Oxidoreductase; n=1; Rhodococcus sp. RHA1|Rep: Oxidoreductase - Rhodococcus sp. (strain RHA1) Length = 242 Score = 85.8 bits (203), Expect = 8e-16 Identities = 62/194 (31%), Positives = 88/194 (45%), Gaps = 4/194 (2%) Frame = +2 Query: 65 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKV 244 LVT L G +VA+ R L + ++ P++ + +DI D + K Sbjct: 8 LVTGAGSGIGAATTLRLLDDGRQVVAIDRDEEALHAHWNDEPAVLLTPLDITDETQVEKC 67 Query: 245 VESLGHF----DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 412 E L D +VN A + SP + D + VNV ++ R M Sbjct: 68 FEDLASRGAIPDRVVNAAGIYRSGSVGMTSPDDVDLLWRVNVHGTYLVTAHATRHM---- 123 Query: 413 THGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 T GAIVNISS A+ A + + Y +K A+++LT +A+ L P IRVNA+ P I T M Sbjct: 124 TRGAIVNISSTAAFLATETNWAYGTTKGAINSLTSGLAVSLAPRNIRVNAVAPGPIATPM 183 Query: 593 AKVGWSDPIKANEM 634 A V DP A M Sbjct: 184 ADVATRDPAYAERM 197 >UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesiocystis pacifica SIR-1|Rep: Short chain dehydrogenase - Plesiocystis pacifica SIR-1 Length = 267 Score = 85.8 bits (203), Expect = 8e-16 Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 10/196 (5%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVDVDIG 220 K +VT L RAGA +V SR LE + + V G Sbjct: 16 KVAIVTGGSRGIGLATATALSRAGAKVVIASRKPEPLEQAAAHIREQTGGEVLAVPAHTG 75 Query: 221 DWEKTRKVV----ESLGHFDALVNNAAVAV-CEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 D E ++VV E+ G D LVNNAA P + S++DKT+DVNVK + + Sbjct: 76 DDEAVQRVVAKTVEAFGGVDVLVNNAATNPHFGPIMSSQDSHWDKTYDVNVKGYFRMVKA 135 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 +M + + G I+NI+S A + +Y SKAA+ LT+ +A+EL I VNA+ Sbjct: 136 CVPEM-QTRGGGRIINIASVAGRRVQPGMGVYCVSKAAVCMLTQVLAVELADAKINVNAL 194 Query: 566 NPTVIMTEMAKVGWSD 613 P + T+ + W + Sbjct: 195 TPGFVKTKFSSAIWGN 210 >UniRef50_A5VEE8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Sphingomonas wittichii RW1 Length = 250 Score = 85.8 bits (203), Expect = 8e-16 Identities = 48/142 (33%), Positives = 77/142 (54%), Gaps = 1/142 (0%) Frame = +2 Query: 212 DIGDWEKTRKVVESLGHFDALVNNAAVA-VCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 D+GD + +VVE++G D LVNN ++ EP P+ + + D+N+ A + Sbjct: 58 DLGDEARISEVVETVGAVDLLVNNGGISGPTEPVATLDPTAWRQVLDINLTAQFLTCHAM 117 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 M+ G IVN+SS A++ + Y+ASKA + LT A+A E+GP GIRVNA+ Sbjct: 118 VPLMLAAGKGGCIVNMSSVAARIGYPNRAAYAASKAGVLGLTAALAREVGPQGIRVNAVL 177 Query: 569 PTVIMTEMAKVGWSDPIKANEM 634 P + + + D +AN++ Sbjct: 178 PATTRGDRIERVFHDYAEANDL 199 >UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Desulfococcus oleovorans Hxd3 Length = 266 Score = 85.8 bits (203), Expect = 8e-16 Identities = 62/192 (32%), Positives = 92/192 (47%), Gaps = 9/192 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHL----ESLQSEYPSIDIVDV 211 S + K LVT AGA++ +SR +L E ++++ V Sbjct: 8 SLENKTALVTGGSMGIGRATALAFADAGADVAIVSRKMENLAPVAEEIKAKGKRCLPVAA 67 Query: 212 DIGDWEKTRKVVESL----GHFDALVNNAAVAVC-EPFLDCSPSNFDKTFDVNVKAVLNI 376 +G ++ +VE + G D LVNNAA + + +D +N+K + + Sbjct: 68 HVGRMDQLPAIVEQVVAEFGQIDILVNNAATSPAYATIFEAQEKLWDSIIGLNLKGLYFL 127 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 SQ VAR M E G+I+N+SS A IYS SKA ++ TR+MALEL P+ IRV Sbjct: 128 SQAVARVMEEKGAGGSIINVSSIDGFAPQAQVGIYSISKAGVNMATRSMALELAPHKIRV 187 Query: 557 NAINPTVIMTEM 592 NAI P T++ Sbjct: 188 NAIAPGATRTKL 199 >UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=3; Trichocomaceae|Rep: 3-ketoacyl-acyl carrier protein reductase - Aspergillus fumigatus (Sartorya fumigata) Length = 256 Score = 85.8 bits (203), Expect = 8e-16 Identities = 40/111 (36%), Positives = 69/111 (62%) Frame = +2 Query: 266 DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQ 445 D LVNNA V++C+ D + + FD+NV ++++++ V + + G I+N+SS Sbjct: 93 DILVNNAGVSLCKNLADTTDHDISSVFDINVYGLISMTRAVIPHL---RAPGRIINLSSV 149 Query: 446 ASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 A++ ++YSASKAA++ TR++A ELGP G VNA+ P + ++M + Sbjct: 150 AARRGSPGFSVYSASKAAVEGFTRSLACELGPVGCTVNAVQPGAVESDMLR 200 >UniRef50_Q8FV67 Cluster: 2-deoxy-d-gluconate 3-dehydrogenase, putative; n=6; Brucellaceae|Rep: 2-deoxy-d-gluconate 3-dehydrogenase, putative - Brucella suis Length = 249 Score = 85.4 bits (202), Expect = 1e-15 Identities = 60/180 (33%), Positives = 87/180 (48%), Gaps = 4/180 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGD 223 S +GK I VT L GA ++++SRT + ESL + + D+ Sbjct: 8 SVRGKVIAVTGGSSGLGLRMVHVLAGHGARVISISRTHAG-ESLCPSGGEVLEIMADVTR 66 Query: 224 WEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 E+ + + G AL NNA VA LD + + F+VNV +Q VA Sbjct: 67 PEEIARAFDEGESRFGPISALFNNAGVAHMARALDTTRDMLEHIFEVNVAGAFFTAQEVA 126 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 R+MI G+I+N++S + K YS SKA + +TRA+ALE + IRVNAI+P Sbjct: 127 RRMIAQGQGGSIINVTSILGERPQKGAAAYSMSKACVSQMTRALALEWAAHDIRVNAISP 186 >UniRef50_Q7UEZ4 Cluster: 1-cyclohexenylcarbonyl CoA reductase-short chain family oxidoreductase; n=1; Pirellula sp.|Rep: 1-cyclohexenylcarbonyl CoA reductase-short chain family oxidoreductase - Rhodopirellula baltica Length = 265 Score = 85.4 bits (202), Expect = 1e-15 Identities = 60/196 (30%), Positives = 93/196 (47%), Gaps = 9/196 (4%) Frame = +2 Query: 29 LKMEISFKGKRILVTXXXXXXXXXXXXELWRAGANI-VALSRTRSHLESLQSEYPS---- 193 +K +GKR LVT EL GA++ + ++ + +E + Sbjct: 9 MKPLADLQGKRALVTGASRGIGRAIALELAARGASVAINFLKSEERAVEVATEISNSGGA 68 Query: 194 IDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVK 361 + +V DI E +VES+ G D +V+NAA D +P NFD N Sbjct: 69 VMLVRADISCKEDVDAMVESVVEKWGGLDIVVSNAAAGGFRDLNDLTPVNFDAVLRSNSA 128 Query: 362 AVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGP 541 V+ ++Q + + E ++HG +V +SS S A+ + ASKAAL+AL R +ALE G Sbjct: 129 PVVWLAQAAWKYLAEGESHGKLVAVSSHGSNWAVPHYGAIGASKAALEALVRHLALEFGD 188 Query: 542 YGIRVNAINPTVIMTE 589 GI N + P +I T+ Sbjct: 189 RGINFNCVLPGIIATD 204 >UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 291 Score = 85.4 bits (202), Expect = 1e-15 Identities = 60/200 (30%), Positives = 100/200 (50%), Gaps = 9/200 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI----VDV 211 S +GK +++T R+G+ IV L S L + + I ++ Sbjct: 15 SLQGKVVVLTGAGGGIASAIVDRFARSGSRIVLLELRTSSLADAEQRLAAAGIESVSIEC 74 Query: 212 DIGDWEKTR----KVVESLGHFDALVNNAA-VAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 D+ D + + VE G D L+NNAA +A +++D+T +N++ V Sbjct: 75 DVADESSVKNAAGRTVEHFGRCDVLINNAATLAPATSIEKLLVADWDRTLAINLRGVFLT 134 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 ++ + M+ N+ G+IVNI+S A+ A Y ASKAA+ A TR A+E GP GIR Sbjct: 135 TKYLGALML-NQGSGSIVNIASIAATAPNASPQ-YGASKAAVLAFTRHTAVEWGPRGIRA 192 Query: 557 NAINPTVIMTEMAKVGWSDP 616 NA++P I T +++ +++P Sbjct: 193 NAVSPGFIRTPLSESNYAEP 212 >UniRef50_Q0K243 Cluster: Short chain dehydrogenase; n=3; Cupriavidus|Rep: Short chain dehydrogenase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 255 Score = 85.4 bits (202), Expect = 1e-15 Identities = 68/199 (34%), Positives = 96/199 (48%), Gaps = 11/199 (5%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSR----TRSHLESLQSEYPSIDIVDVDIG 220 G+ ++T L AGA +V R R L++E + DI Sbjct: 9 GRVAVITGSTRGMGLEMARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRATGIACDIA 68 Query: 221 DWEKTRKVVE----SLGHFDALVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 382 D + R E + G DALV NAA A +P L P FD NV+ L + Sbjct: 69 DVDSVRAFAEQALAAYGRVDALVLNAA-ASGQPGSMLSQGPEVFDAAMAGNVRGNLVLVN 127 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 +A +MI ++ G+I+ +SS A+K +YS +KAA+D R++ALELGP GI VNA Sbjct: 128 ALAPQMI-SRHDGSIIFMSSIAAKRGSAFLGMYSVTKAAIDQAVRSLALELGPSGINVNA 186 Query: 563 INPTVIMTEMAKVG-WSDP 616 INP + TE ++ W DP Sbjct: 187 INPGPVRTEFSRDALWGDP 205 >UniRef50_A1UGA6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 248 Score = 85.4 bits (202), Expect = 1e-15 Identities = 48/108 (44%), Positives = 66/108 (61%) Frame = +2 Query: 266 DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQ 445 D LVNNA V + P + +FD TF VNV+ L ++Q + E +IVN+SS Sbjct: 85 DVLVNNAGVGLFAPLGAITVEDFDATFAVNVRGPLFVTQAFLPHLSEG---ASIVNVSSS 141 Query: 446 ASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 589 S+ ++Y+ASK AL+ALTR++ALELGP GIRVN+I P T+ Sbjct: 142 LSRHVSPAASVYAASKKALEALTRSLALELGPRGIRVNSIAPGPTATD 189 >UniRef50_A1DLG7 Cluster: Short-chain dehydrogenase/reductase, putative; n=5; Pezizomycotina|Rep: Short-chain dehydrogenase/reductase, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 319 Score = 85.4 bits (202), Expect = 1e-15 Identities = 54/162 (33%), Positives = 85/162 (52%), Gaps = 5/162 (3%) Frame = +2 Query: 119 RAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL-----GHFDALVNN 283 + G + A +R + ++ L+ +DI+ +D+ D E R+ VE++ G D LVNN Sbjct: 54 KKGMRVFASARNLAKVQHLKDM--GLDIIRLDVADEESIREAVETVKAATGGTLDFLVNN 111 Query: 284 AAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAAL 463 + P LD S K FDVNV V+ ++Q A +I ++ I+NI S K L Sbjct: 112 SGSGYAIPLLDSDVSVAKKMFDVNVFGVVTVTQAFAPLLIASQE--TIINIGSVLGKMPL 169 Query: 464 KDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 589 Y+ASKAA+ +T M +EL P+G+R +N V+ T+ Sbjct: 170 PWQGYYNASKAAVALITDQMRIELSPWGVRAILVNTGVVRTK 211 >UniRef50_Q815Q6 Cluster: Short chain dehydrogenase; n=1; Bacillus cereus ATCC 14579|Rep: Short chain dehydrogenase - Bacillus cereus (strain ATCC 14579 / DSM 31) Length = 256 Score = 85.0 bits (201), Expect = 1e-15 Identities = 60/196 (30%), Positives = 87/196 (44%), Gaps = 9/196 (4%) Frame = +2 Query: 38 EISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP--------S 193 + +FK K I +T G N++ LS T L L+ + Sbjct: 6 QFNFKNKNIFITGATSDIAICIAESFSGFGGNLI-LSDTDKQLPKLEHVKQKMIEKFRNN 64 Query: 194 IDIVDVDIGDWEKTRKVVESLGH-FDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 + IV +D+ + +E L D L+N A P L+ S N+ K DVN+K Sbjct: 65 VQIVTIDLYKVNDIQNAIEKLDKPIDILINCAGNNYFVPALEVSEENWQKIIDVNLKGTF 124 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 +SQ +A+KMI + G IVNI SQ A Y SK L LT+ +ALE + I Sbjct: 125 FLSQSIAKKMISDGIKGKIVNIGSQHGVVANGLRAPYCISKFGLIGLTKVLALEWSTFNI 184 Query: 551 RVNAINPTVIMTEMAK 598 VN ++PT + T +K Sbjct: 185 LVNCVSPTYVKTSKSK 200 >UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=1; Bdellovibrio bacteriovorus|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Bdellovibrio bacteriovorus Length = 249 Score = 85.0 bits (201), Expect = 1e-15 Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 5/193 (2%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDI 202 + FK K +VT AG N+ + + L++ +SE+ I I Sbjct: 4 INFDFKNKNAIVTGGASGIGFQITKSFLEAGGNVSIWDYSEAALQTAKSEFAKYGSQIHI 63 Query: 203 VDVDIGDWEKTRKVVESLGH-FDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 VD+G+ + K SL D LVNNA + + F SP ++D N+ + N++ Sbjct: 64 AQVDVGNRDSVAKAAASLPWTVDILVNNAGITRDKSFAKMSPEDWDAVISTNLTGLFNVT 123 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + V K N I+NI+S + T Y A+KA + +++ A ELG G N Sbjct: 124 KSVLEKFNPNSNSKRIINIASVVALYGNFGQTNYVAAKAGVIGMSKTWAKELGRKGFTSN 183 Query: 560 AINPTVIMTEMAK 598 AI P I T M K Sbjct: 184 AIAPGFIATAMTK 196 >UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxidoreductase - Geobacillus kaustophilus Length = 260 Score = 85.0 bits (201), Expect = 1e-15 Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 12/196 (6%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV----DI 217 +GK +VT L AGAN+V SR E ++ + + + + D+ Sbjct: 10 EGKTAIVTGGGRGLGEQIAVGLAEAGANVVVCSRKVEACEQVKEKLEQLGVRSLALRCDV 69 Query: 218 GDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + E+ + VVE+ G D LVNN+ P + + K +VNV +SQ Sbjct: 70 TNPEEVKHVVETTVKEFGGIDILVNNSGATWGAPVEEMPLEAWQKVINVNVTGTFLMSQA 129 Query: 386 VARKMIENKTHGAIVNISSQASKAALKD---HTI-YSASKAALDALTRAMALELGPYGIR 553 V + MI +T G+I+NI+S A +TI Y+ SK A+ TR +A + G +GIR Sbjct: 130 VGKVMIAKQTGGSIINIASVAGLGGTHPDILNTIGYNTSKGAVITFTRDLAAKWGKHGIR 189 Query: 554 VNAINPTVIMTEMAKV 601 VNA+ P T+M+KV Sbjct: 190 VNAVAPGFFPTKMSKV 205 >UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 254 Score = 85.0 bits (201), Expect = 1e-15 Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 8/191 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDV 211 + +GK +VT L AGA + +RT + LES ++ + Sbjct: 7 NLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVAARTSAELESFVADAKAAGGQALACST 66 Query: 212 DIGDWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 DI D ++V E+ G D LVNN+ + P ++ S +D+ N++ + Sbjct: 67 DITDEASVERLVDATVETFGRVDILVNNSGIVATTPLIEQSADEWDRVVATNLRGTFLAT 126 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + V R ++ ++ G ++NI+S + + +H YSASKA + A TR+MA+E I+VN Sbjct: 127 RAVGRHLVAQRS-GKVINIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQVN 185 Query: 560 AINPTVIMTEM 592 AI P T + Sbjct: 186 AIAPGYFATSL 196 >UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 249 Score = 84.6 bits (200), Expect = 2e-15 Identities = 56/192 (29%), Positives = 93/192 (48%), Gaps = 9/192 (4%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDV 211 S GK LVT +L AGA + +R LE L+ + + ++++ Sbjct: 3 SLNGKIALVTGASSGIGAATAAKLAEAGAKVGIAARRTDKLEDLKKKIEAKGGEALVIEM 62 Query: 212 DIGDWEKT----RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ D +K+V++ G D LVNNA + + + DVNVK +LN + Sbjct: 63 DVVDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTT 122 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELG-PYGIRV 556 V +MI+ + G + N+SS A + K ++Y A+K A+ A + + +E+G +GIRV Sbjct: 123 AAVLPQMIKQHS-GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGLRMEVGQKHGIRV 181 Query: 557 NAINPTVIMTEM 592 I P + TE+ Sbjct: 182 TCIQPGAVATEL 193 >UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep: Bll5898 protein - Bradyrhizobium japonicum Length = 256 Score = 84.6 bits (200), Expect = 2e-15 Identities = 60/188 (31%), Positives = 89/188 (47%), Gaps = 6/188 (3%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS----IDIVDVD 214 FK K ++VT GA +V R S L + +E + I DV Sbjct: 5 FKDKVVIVTGAGSGIGAAAARRFHGEGAIVVLNGRRESKLAEVGAELGTDRCMIRPADVT 64 Query: 215 IG-DWEK-TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 I D E V G D LVNNA FL + F VNV VL +++ Sbjct: 65 IAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVDGVLYMTRAA 124 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 +IE+ G+IVN+SS + + + Y+A+K A+ LTR++ALE GP G+R+NA+ Sbjct: 125 LPHLIESG--GSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLALEFGPRGVRINAVC 182 Query: 569 PTVIMTEM 592 P++ +T + Sbjct: 183 PSLTLTHL 190 >UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 296 Score = 84.6 bits (200), Expect = 2e-15 Identities = 58/198 (29%), Positives = 89/198 (44%), Gaps = 9/198 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID-----IV 205 + G+ +VT L GA++ +RT LE ++ + V Sbjct: 41 LDLTGRVAIVTGGGTGIGAATARLLAAHGADVAVAARTVDELERTAADIRAATGRRCLAV 100 Query: 206 DVDIGDWEKT----RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 D+ D E+ R+ VE LG D LVNNA P +D +FD+NV+A Sbjct: 101 PTDVKDEEQVIRLVRRTVEELGRIDVLVNNAGGTRMGPLSSLPTRAWDASFDLNVRAAYF 160 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 ++ R ++ ++ GAIVNISS A ++ Y+++KAAL T A E G YG+R Sbjct: 161 CTREAGRHLVAQRS-GAIVNISSDAGLHGVRGGAHYASAKAALQMFTTVTAAEWGRYGVR 219 Query: 554 VNAINPTVIMTEMAKVGW 607 N + + +E A W Sbjct: 220 ANCLAVGPVASERAVEAW 237 >UniRef50_A5USD0 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 235 Score = 84.6 bits (200), Expect = 2e-15 Identities = 44/114 (38%), Positives = 68/114 (59%) Frame = +2 Query: 257 GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNI 436 G D ++NNA VA L ++ D+ F+ NV+ V + + AR M + + G IVN+ Sbjct: 72 GRLDIVINNAGVAAMNHSLLTPLASVDRIFNTNVRGVFLVCREAARLM-QRRRFGRIVNL 130 Query: 437 SSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 S+ A L+ +Y+ASK+A++ LTR +A E GP GI VNA+ PT I T++ + Sbjct: 131 STVAVPLRLEGEALYAASKSAVEMLTRILAREFGPLGITVNAVGPTPIETDLIR 184 >UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Methylobacterium sp. 4-46 Length = 275 Score = 84.6 bits (200), Expect = 2e-15 Identities = 50/136 (36%), Positives = 74/136 (54%), Gaps = 4/136 (2%) Frame = +2 Query: 203 VDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 V VD+ D +VE++ G D LVNNA V PFL+ ++++ +N+ Sbjct: 61 VAVDVADPASIAAMVEAILARHGRLDILVNNAGVGGNTPFLETRLEDWNRIIGINLTGAF 120 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 ++Q AR+M+ G IVNI+S + + Y A+KA L+ LT+ MA+EL +GI Sbjct: 121 LVAQACAREMVRGGG-GKIVNIASLSGQRGGDGRAAYGAAKAGLELLTKVMAVELSEHGI 179 Query: 551 RVNAINPTVIMTEMAK 598 VN I P I TEMA+ Sbjct: 180 NVNNIAPGAIETEMAR 195 >UniRef50_A1BBU8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Paracoccus denitrificans PD1222|Rep: Short-chain dehydrogenase/reductase SDR precursor - Paracoccus denitrificans (strain Pd 1222) Length = 255 Score = 84.6 bits (200), Expect = 2e-15 Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 5/207 (2%) Frame = +2 Query: 32 KMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV 211 K S +GKR LVT + AGA ++ + R + LE P + V Sbjct: 6 KRAFSLEGKRALVTGGGSGLGEAMAAAMAAAGAKVILVGRRKDMLEQAAGRIPGAKVETV 65 Query: 212 DIGDWEK----TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ D + ++E G D LVNNA + +PFL+ + + D DV+++ L S Sbjct: 66 DLADIAALDAAAKAILERHGKIDILVNNAGNTIRKPFLETTYEDIDAVVDVHLRGALEFS 125 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + + + E G ++ +S AS L Y+ +K AL + RA++ E +RVN Sbjct: 126 RPIIARQAET-GGGCVIFTASMASYMGLPYVMGYTVAKTALLGVVRALSAEFAGQNVRVN 184 Query: 560 AINPTVIMTEMAK-VGWSDPIKANEML 637 I P I T + + +DP + + L Sbjct: 185 GIAPGWIDTPLYRGATGADPARKAKAL 211 >UniRef50_Q9FJP5 Cluster: Similarity to dehydrogenase; n=9; core eudicotyledons|Rep: Similarity to dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 341 Score = 84.6 bits (200), Expect = 2e-15 Identities = 59/166 (35%), Positives = 83/166 (50%), Gaps = 4/166 (2%) Frame = +2 Query: 125 GANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVV----ESLGHFDALVNNAAV 292 G +VA SR++ + L+ + + ++D+ + KVV + G D LVNNA V Sbjct: 33 GCRVVATSRSQKTMTELEKD-SKFFVQELDVQSEQSVSKVVSKVIDKFGQIDVLVNNAGV 91 Query: 293 AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDH 472 P + S D TF+ NV + ++Q V M K G IVNI S + A Sbjct: 92 QCIGPLAEIPISAMDYTFNTNVLGSMRMTQAVVPHMASKKK-GKIVNIGSISIMAPGPWA 150 Query: 473 TIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWS 610 +Y+ASKAAL ALT + LEL P+GI V I P I + +A G S Sbjct: 151 GVYTASKAALHALTDTLRLELKPFGIDVINIVPGGIQSNIANSGIS 196 >UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 246 Score = 84.2 bits (199), Expect = 2e-15 Identities = 55/190 (28%), Positives = 89/190 (46%), Gaps = 9/190 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVA-LSRTRSHLESLQSEYPSIDI----VDVD 214 +GK +VT EL R GAN+V + + E + +E + + + D Sbjct: 3 QGKTAIVTGASRGIGRATAMELARHGANVVVNYAGNKEKAEKVVAEIKELGVEAIAIQAD 62 Query: 215 IGDWEKT----RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 + D E ++ +++ G D LVNNA + F+ ++D D N+K V + S+ Sbjct: 63 VADSESVQAMVKETIDTFGAVDILVNNAGITRDNLFMRMKEEDWDAVIDTNLKGVFHCSK 122 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 V R M++ + G I+N+SS Y A+KA + LT+ +A EL I VNA Sbjct: 123 AVTRPMMKQR-FGRIINVSSVVGAIGNAGQANYVAAKAGVIGLTKTLARELANRNITVNA 181 Query: 563 INPTVIMTEM 592 + P I T+M Sbjct: 182 VAPGFIETDM 191 >UniRef50_Q982J8 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Mesorhizobium loti|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Rhizobium loti (Mesorhizobium loti) Length = 258 Score = 84.2 bits (199), Expect = 2e-15 Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 6/182 (3%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGD 223 + K KR ++T ++ AGA + + S +E P V D+ D Sbjct: 3 ALKDKRAIITAGASGIGRVVTKKMIAAGAKVAVCDVDEDAVNSFAAENPDSTAVVCDVAD 62 Query: 224 WEKTRKVVESL-----GHFDALVNNAAVAVCEPFL-DCSPSNFDKTFDVNVKAVLNISQV 385 K + +E++ G D L NNA +A + D SP + +T DVN+ A + Sbjct: 63 PTKVPEAIETMLKGLGGGTDILFNNAGIAGPTAAIEDISPEEWGRTLDVNLTAQYLFIRG 122 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 V M ++ G I+N+SS A + + T Y+A+K A+ LT+++A+E+G +GIRVNAI Sbjct: 123 VMAGMKAQRS-GVILNMSSAAGRLGMPMRTPYAAAKWAVIGLTQSLAMEVGKFGIRVNAI 181 Query: 566 NP 571 P Sbjct: 182 LP 183 >UniRef50_Q7UPP3 Cluster: Gluconate 5-dehydrogenase; n=1; Pirellula sp.|Rep: Gluconate 5-dehydrogenase - Rhodopirellula baltica Length = 286 Score = 84.2 bits (199), Expect = 2e-15 Identities = 51/194 (26%), Positives = 95/194 (48%), Gaps = 11/194 (5%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALS-----RTRSHLESLQSEYPSIDIVDVDI 217 G+R++VT L GA++V + T + L S + + +++ D+ Sbjct: 29 GRRVVVTGGTQGVGGAIARGLTSVGADVVLIGLERDPATEATLVSCRENGRTAELILCDL 88 Query: 218 GDWEKT------RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 +T ++ + D LVNNA + PFL+ +P + T ++NV A ++ Sbjct: 89 SKPAETWIDDLLAQIDRVMPGVDTLVNNAGTFIDVPFLEMTPDRYQTTMNLNVGAGYFLT 148 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 Q A++ ++N+ G ++ S A DHT Y SK A+ ++ R++ + L P+GIRVN Sbjct: 149 QAFAKRWVQNQVAGRVLFTGSINGFLAEPDHTAYDTSKGAVASMVRSLCVSLAPHGIRVN 208 Query: 560 AINPTVIMTEMAKV 601 ++ P ++ T + V Sbjct: 209 SMAPGLVRTRLTDV 222 >UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 286 Score = 84.2 bits (199), Expect = 2e-15 Identities = 54/186 (29%), Positives = 85/186 (45%), Gaps = 8/186 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI----VDVDIG 220 G+ VT L AGAN+ L E + D+ Sbjct: 9 GQAAFVTGGGGGIGRAIAIRLAEAGANVAILDIIAERAEETATRIRETGARALTFPADVM 68 Query: 221 DWEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 + + R ++ + G D LVNNA PFL+ S + K D+N+ ++L +Q Sbjct: 69 ESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQAA 128 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 AR M+ G+I+N++S + A + +Y+A KA + + TR+MALEL +GIRVN + Sbjct: 129 ARHMVAGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMALELSGHGIRVNCLA 188 Query: 569 PTVIMT 586 P +T Sbjct: 189 PDHTVT 194 >UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=4; Actinomycetales|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 260 Score = 84.2 bits (199), Expect = 2e-15 Identities = 61/197 (30%), Positives = 98/197 (49%), Gaps = 6/197 (3%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI-VDVDI 217 + G+ +VT + AG N+V SR++ ++ ++ I + Sbjct: 4 LDLTGRTAIVTGASRGIGLAVAKAIAAAGGNVVLTSRSQESADAAAAQVGGTAIGIAAHA 63 Query: 218 GDWEKTRKVV----ESLGHFDALVNNAAVAVC-EPFLDCSPSNFDKTFDVNVKAVLNISQ 382 D E R+ V E G D LVNNA P +D + F KTFDVN+ A + + Sbjct: 64 VDEEAARRCVDVTLERFGSLDILVNNAGTNPSFGPVIDQDHARFAKTFDVNLWAPVLWTG 123 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 +V + + + GA+VN +S A + +Y+ASKAAL +T+ +ALEL P +RVNA Sbjct: 124 LVTKAWM-GEHGGAVVNTASIGGMAFEANIGLYNASKAALIHVTKQLALELSP-KVRVNA 181 Query: 563 INPTVIMTEMAKVGWSD 613 + P V+ T++A+ W + Sbjct: 182 VAPGVVRTKLAEALWKE 198 >UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MWYL1|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 252 Score = 84.2 bits (199), Expect = 2e-15 Identities = 64/191 (33%), Positives = 89/191 (46%), Gaps = 10/191 (5%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVA--LSRTRSHLESLQSEYPSID----IVDVDI 217 K +LVT L GA++V L R L +S + + DI Sbjct: 7 KVVLVTGASRGIGRALAEGLAEHGADVVICDLPREEKGLNEAKSAIEKLGRKCWVFGADI 66 Query: 218 GDWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 D +V E GH D LVNNA + D S ++D F VN K +L ++ Sbjct: 67 TDKSAVENMVAQATEQAGHIDVLVNNAGILKPSLLEDLSEGDWDAHFAVNGKGLLFVTNA 126 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 V +M + K +G I+NI+S A++ + Y+A+KA LTR A E G GI VNAI Sbjct: 127 VLPQMRQRK-NGRIINIASIAARQGVPTQGHYAATKATAVTLTRVYAQETGMDGITVNAI 185 Query: 566 NPTVIMTEMAK 598 P +I+TEM K Sbjct: 186 CPGIILTEMGK 196 >UniRef50_A4AIS2 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reductase; n=5; Bacteria|Rep: 3-ketoacyl-(Acyl-carrier-protein) reductase - marine actinobacterium PHSC20C1 Length = 253 Score = 84.2 bits (199), Expect = 2e-15 Identities = 57/186 (30%), Positives = 90/186 (48%), Gaps = 4/186 (2%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP--SIDIVDVDIG 220 F G+ I+VT L GA ++A ++ L+ L SE S+ IV D+ Sbjct: 10 FNGRTIIVTGAGSGIGKATAVRLLSEGARVIASDISQPRLDELASESATDSLVIVPGDVS 69 Query: 221 DWEKTRKVVESLG-HFDALVNNAAVA-VCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 K+V + G D LVNNA + P + + +D+ VN+ A + + + V Sbjct: 70 AQADVDKIVAAAGGRVDGLVNNAGIMDAFLPTAEITDEMWDRVMGVNLTAQMRLIRAVLP 129 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 MI+ + G IVN++S+A + T YS SK + LT++ A GP G+R NA+ P Sbjct: 130 TMIDAE-FGRIVNLASEAGIKSGASGTTYSVSKHGVIGLTKSTAFFYGPKGVRCNAVAPG 188 Query: 575 VIMTEM 592 +MT + Sbjct: 189 AVMTNI 194 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 84.2 bits (199), Expect = 2e-15 Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 9/209 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHL-ESLQS--EYP-SIDIVD 208 + K K ++VT + GAN+V L ES+Q E+ ++ + Sbjct: 20 MKLKNKTVIVTGAAQGLGYACALRFLQDGANVVMADVNAEKLAESVQDLIEFDGAVSSMV 79 Query: 209 VDIGDWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 D+ E + +V + G+ D ++NNA +A + FL+ S +D DVN++ Sbjct: 80 CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 556 +Q+ ++MI G I+N+SS + A + Y+ SK ++ LT A+ L P+ IRV Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPHNIRV 199 Query: 557 NAINPTVIMTEM-AKVGWSDPIKANEMLS 640 I P I+T+M A V + P + +LS Sbjct: 200 CGIGPGTILTDMVADVIMTSPEARHNVLS 228 >UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Stappia aggregata IAM 12614|Rep: Short-chain dehydrogenase/reductase SDR - Stappia aggregata IAM 12614 Length = 270 Score = 84.2 bits (199), Expect = 2e-15 Identities = 62/191 (32%), Positives = 93/191 (48%), Gaps = 11/191 (5%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIG 220 G+ LVT L + GA +V +R+ +E +++E V D+ Sbjct: 23 GQVALVTGASRGIGEAAARSLAKYGAKVVLAARSDKDIERIAGEIRAEGQDATAVVCDVA 82 Query: 221 DWEKTRKVVESL----GHFDALVNNAAVAVCEPFL---DCSPSNFDKTFDVNVKAVLNIS 379 D++ K V++ G D LVNNA V EP D P+ + K D+NVK V Sbjct: 83 DYDDVVKAVQTAVDTYGGLDILVNNAGVI--EPIARIEDSDPAEWGKVIDINVKGVYYGL 140 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 A+ M+ K G +VNISS A+ +AL+ + Y ASKAA +LTR E G G+R+ Sbjct: 141 HAAAKHMLA-KGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADKEFGDKGLRIV 199 Query: 560 AINPTVIMTEM 592 ++P + T+M Sbjct: 200 GLSPGTVATQM 210 >UniRef50_A7RYX9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 237 Score = 84.2 bits (199), Expect = 2e-15 Identities = 54/182 (29%), Positives = 87/182 (47%), Gaps = 2/182 (1%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWE 229 K K ++++ R GA ++A L+ L S P I+ VD+ D+E Sbjct: 15 KNKVVVLSAAAQGIGKATALACAREGAKVIATDINAEKLKELHS-VPGIETRVVDVTDYE 73 Query: 230 KTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN-ISQVVARKMIE 406 +K + D L N A + + +CS +D T D+NVK+++N + ++ K Sbjct: 74 AIKKFASEVDRVDVLFNCAGLVLGGNIEECSEKQWDLTMDLNVKSMVNHLCSLILLKFPH 133 Query: 407 NKTHGAIVNISSQASK-AALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 583 G+I+N++S AS + Y SKAA+ T+A+A + GIRVNA+ P I Sbjct: 134 KLWSGSIINMASVASSIKGAPNRFAYGTSKAAVIGFTKAIAADYITKGIRVNAVCPGTIY 193 Query: 584 TE 589 TE Sbjct: 194 TE 195 >UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) Length = 256 Score = 84.2 bits (199), Expect = 2e-15 Identities = 56/181 (30%), Positives = 86/181 (47%), Gaps = 5/181 (2%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-PSIDIVDVDIGDWE 229 GK L+T R GA + + +E P+ + +D+ D Sbjct: 5 GKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVTDQA 64 Query: 230 KTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 + V L G D LVNNAA+ P ++ + ++D+ F +NV L + Q VAR Sbjct: 65 SIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQAVARA 124 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 MI G I+N++SQA + +Y A+KAA+ +LT++ L L +GI VNAI P V Sbjct: 125 MIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAIAPGV 184 Query: 578 I 580 + Sbjct: 185 V 185 >UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 257 Score = 83.8 bits (198), Expect = 3e-15 Identities = 46/119 (38%), Positives = 75/119 (63%), Gaps = 1/119 (0%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 +V+ES D LVNNA + LD + S++ +T DVN+ A+ S+ V + M+ N + Sbjct: 82 RVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQVGKHMVANGS- 140 Query: 419 GAIVNISSQASKAALKD-HTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 G+I+N+SS ++ A ++ + Y+ASK A+ LT+++A E YGIRVNAI P + ++M Sbjct: 141 GSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLASEWAQYGIRVNAIAPGYMASQM 199 >UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1; Oceanicola granulosus HTCC2516|Rep: Short-chain alcohol dehydrogenase - Oceanicola granulosus HTCC2516 Length = 245 Score = 83.8 bits (198), Expect = 3e-15 Identities = 59/187 (31%), Positives = 90/187 (48%), Gaps = 5/187 (2%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGD--- 223 GK ILVT AGA++V + R + + + P V++D+ D Sbjct: 7 GKCILVTGAGDGIGRAAARLFAEAGAHLVLVDRHGAQATA-DAHCPGALAVEMDVRDGAG 65 Query: 224 WEK-TRKVVESLGHFDALVNNAAVAVC-EPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 W++ + G DALVNNA +AV + D S +D D+N K V + V Sbjct: 66 WDRLVAEATARFGGIDALVNNAGIAVPGDTVTDASEEMWDDILDINAKGVWLGMRAVLPG 125 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 M+E + G I N++S A+ L Y ASK A+ ALTR ++ P GI++N+++P Sbjct: 126 MVE-RGGGHICNVASTAAHIGLPGAAAYCASKGAVLALTRQAGVQYAPLGIKINSVSPGT 184 Query: 578 IMTEMAK 598 MT + K Sbjct: 185 TMTGIQK 191 >UniRef50_A7MMI9 Cluster: Putative uncharacterized protein; n=1; Enterobacter sakazakii ATCC BAA-894|Rep: Putative uncharacterized protein - Enterobacter sakazakii ATCC BAA-894 Length = 256 Score = 83.8 bits (198), Expect = 3e-15 Identities = 55/150 (36%), Positives = 84/150 (56%), Gaps = 1/150 (0%) Frame = +2 Query: 125 GANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCE 304 G N++A RT SL E + I+ +DI E R VV+ G D LVNNA V Sbjct: 25 GWNVIATMRTPD--PSLFPESDRLTILPLDITSEESIRAVVKRAGAIDLLVNNAGVGAPV 82 Query: 305 PFLDCSP-SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIY 481 P ++ +P + + + NV L ++Q +M E K+ G I+N+SS + A+ +Y Sbjct: 83 P-VELTPLATAQQLMNTNVLGTLLLTQAFLPQMREQKS-GVIINVSSSITTKAMPLIGLY 140 Query: 482 SASKAALDALTRAMALELGPYGIRVNAINP 571 ASKAAL+A + ++ALE+ P+GIRV+ + P Sbjct: 141 RASKAALNAWSESLALEVRPFGIRVHVVLP 170 >UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain dehydrogenase/reductase SDR - Xanthobacter sp. (strain Py2) Length = 255 Score = 83.8 bits (198), Expect = 3e-15 Identities = 62/194 (31%), Positives = 95/194 (48%), Gaps = 11/194 (5%) Frame = +2 Query: 38 EISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES---------LQSEYP 190 ++ GK LVT L R GA++V R + E+ +++ Sbjct: 4 DLDLSGKVALVTGAASGIGLAAAQLLARQGAHVVLADRDGAAAEAAAQALGAAGMRASSQ 63 Query: 191 SIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 + D+ D + E +V+ +LG D LVNNA +++ + D + S+++K F VNV Sbjct: 64 AFDVTD-EAAVGEGVAQVLAALGRVDILVNNAGLSIRKGIADLALSDWEKVFAVNVTGAF 122 Query: 371 NISQVVARKMIENKTHGAIVNISS--QASKAALKDHTIYSASKAALDALTRAMALELGPY 544 ++ V M + GAIVNI+S S + Y ASK A+ LTR +A+EL P Sbjct: 123 LTTRAVVPAM-RAQGAGAIVNIASIMGLSGGGPYPNPAYQASKGAIVNLTRGLAVELAPA 181 Query: 545 GIRVNAINPTVIMT 586 GIRVNA+ PT + T Sbjct: 182 GIRVNAVAPTWVRT 195 >UniRef50_A6G9T9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Plesiocystis pacifica SIR-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Plesiocystis pacifica SIR-1 Length = 218 Score = 83.8 bits (198), Expect = 3e-15 Identities = 41/119 (34%), Positives = 67/119 (56%) Frame = +2 Query: 236 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 ++VV LG LVNNA +++ + P + + VN++ L S+ +R ++ +K Sbjct: 44 KRVVGELGGLQILVNNAGISIDALLMRAKPEDMRRILAVNLEGALTCSKAASRHLLRSKA 103 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 G I+N+SS + ++Y+ASKA L LT++MA EL G+ VNA+ P I T+M Sbjct: 104 RGRIINLSSVVGETGNAGQSMYAASKAGLLGLTKSMAQELAARGVTVNAVTPGFIETDM 162 >UniRef50_A1W2L0 Cluster: Short-chain dehydrogenase/reductase SDR; n=14; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Acidovorax sp. (strain JS42) Length = 258 Score = 83.8 bits (198), Expect = 3e-15 Identities = 53/187 (28%), Positives = 89/187 (47%), Gaps = 7/187 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDVDIG 220 GKR+LVT L GA + +R L+ + + +D+ Sbjct: 13 GKRVLVTGASSGLGQHFARLLAAQGAQVALAARRTDKLQGTVDDINAAGGQARACALDVT 72 Query: 221 DWEKTRKVVESLGHF---DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 D R + L + D ++NNA V V P L+ + ++FD+ D N+K ++ A Sbjct: 73 DSASVRACFDDLADWGVPDVVINNAGVTVTRPLLEQTEADFDQVLDTNLKGCWLVATEAA 132 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 R+M+ G++VN++S + Y+ SKA + T+AMALEL + IRVNA+ P Sbjct: 133 RRMVVAGKGGSVVNVASILGERVAGGVAPYAISKAGVIQATKAMALELARHRIRVNALLP 192 Query: 572 TVIMTEM 592 ++T++ Sbjct: 193 GYVVTDL 199 >UniRef50_Q3EBY4 Cluster: Uncharacterized protein At2g17845.1; n=24; Magnoliophyta|Rep: Uncharacterized protein At2g17845.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 312 Score = 83.8 bits (198), Expect = 3e-15 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 17/207 (8%) Frame = +2 Query: 29 LKMEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSE-----YPS 193 L + K K +LVT +L +AG I+A +R L+SL SE Y + Sbjct: 41 LYLTCELKDKVVLVTGASSGIGREVCLDLAKAGCKIIAAARRVDRLKSLCSEINRFEYSA 100 Query: 194 ---IDIVDVDIGDWEKT-----RKVVESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTF 346 + +++D+ T +K E G DAL+NNA + LD S +DK F Sbjct: 101 GIQAEALELDVSSDAATVQKAVKKAWEIFGKIDALINNAGFRGNVKSSLDLSEDEWDKVF 160 Query: 347 DVNVKAVLNISQVVARKMIENKTHG-AIVNISSQA--SKAALKDHTIYSASKAALDALTR 517 N+ +S+ V M + K G +++NISS + + + Y+ SK +D +TR Sbjct: 161 KTNLTGTWLVSKYVCILMRDAKRGGGSVINISSVSWLHRGQVPGGVAYACSKGGVDTMTR 220 Query: 518 AMALELGPYGIRVNAINPTVIMTEMAK 598 MALELG Y IRVN+I P ++ +E+ + Sbjct: 221 MMALELGVYKIRVNSIAPGLLKSEITQ 247 >UniRef50_A7D6X0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Short-chain dehydrogenase/reductase SDR - Halorubrum lacusprofundi ATCC 49239 Length = 257 Score = 83.8 bits (198), Expect = 3e-15 Identities = 58/192 (30%), Positives = 92/192 (47%), Gaps = 5/192 (2%) Frame = +2 Query: 38 EISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRT-RSHLESLQSEYP-SIDIVDV 211 E +F G+ +L+T GA +V R +S ++ P + + V Sbjct: 11 EPAFAGETVLITGTARGIGRACAVRFAERGATVVGGDRLDQSETAGTCTDLPGAFEPVAA 70 Query: 212 DIGDWEKTRKVVE---SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 D+ D E +VE G DA+VN A + EP ++++ VN+ A I++ Sbjct: 71 DVTDPEAVEALVERAADTGRVDAVVNVAGIVAREPLATHDGEPWERSVAVNLTAPFRIAR 130 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 A + KT GA+VNISS + + Y+++KA ++ LTRA+A ELG G+R NA Sbjct: 131 EAAPHL--RKTGGAVVNISSIYGQIGAAERAGYASTKAGIEGLTRALAAELGEDGVRANA 188 Query: 563 INPTVIMTEMAK 598 + P I T M + Sbjct: 189 VAPGFIETPMTE 200 >UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Leptospira interrogans Length = 254 Score = 83.4 bits (197), Expect = 4e-15 Identities = 60/194 (30%), Positives = 89/194 (45%), Gaps = 10/194 (5%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVAL------SRTRSHLESLQSEYPSIDI 202 I KGK +VT L +AGAN+V S+ + S Q+ +I I Sbjct: 2 IDLKGKNAVVTGAARGIGKSTALTLAKAGANLVIADLNEESSKATADEISKQTGVKAIGI 61 Query: 203 VDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 ++ D + K +++ G D LVNNA + + +D VN+ Sbjct: 62 -GTNVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTF 120 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 N +Q + M++N G+I+N+SS A T YSASKA + T+A+ALE+ + Sbjct: 121 NCTQAAIKFMMKNPNGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKV 180 Query: 551 RVNAINPTVIMTEM 592 R NAI P I TEM Sbjct: 181 RCNAIAPGFIATEM 194 >UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Clostridium beijerinckii NCIMB 8052 Length = 246 Score = 83.4 bits (197), Expect = 4e-15 Identities = 48/135 (35%), Positives = 75/135 (55%), Gaps = 1/135 (0%) Frame = +2 Query: 212 DIGDWEKT-RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 +I D EK + + G D L+NNA V + + D + FDK F++NVK Q Sbjct: 67 NIKDVEKLFSETITKFGRVDILINNAGVILYKLLSDVTEEEFDKLFNINVKGTYFACQQ- 125 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 A K +EN +G I+N S+ + +++Y+A+K A++ +TR +A E GP I +NA+ Sbjct: 126 AMKHMEN--NGRIINFSTSVVGSMFPTYSVYAATKGAVEQITRQLAKEFGPKKITINAVA 183 Query: 569 PTVIMTEMAKVGWSD 613 P I TE+ VG +D Sbjct: 184 PGPINTELFNVGKTD 198 >UniRef50_A6ERE9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase SDR - unidentified eubacterium SCB49 Length = 245 Score = 83.4 bits (197), Expect = 4e-15 Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 4/153 (2%) Frame = +2 Query: 164 LESLQSEYPSIDIVDVDIGDWEKTRKV----VESLGHFDALVNNAAVAVCEPFLDCSPSN 331 + ++S S V D+ D ++ + +E+ G D LVNNA + + D + + Sbjct: 48 VHEIKSNGGSAISVKADVSDRDQVTHLFDAALEAFGKIDVLVNNAGTMISKKIKDNTQED 107 Query: 332 FDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDAL 511 F + FDVNV+ V N Q K+ +N G I+N SS +K L + +YSA+KAA++ + Sbjct: 108 FTRQFDVNVRGVFNALQEADGKLEDN---GIIINFSSSTTKLMLPTYGLYSATKAAVEQM 164 Query: 512 TRAMALELGPYGIRVNAINPTVIMTEMAKVGWS 610 TR A E+G GI VNAI P T + G S Sbjct: 165 TRVYAKEIG-RGISVNAIAPGATETTLFLTGKS 196 >UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Dehalococcoides|Rep: Short-chain dehydrogenase/reductase SDR - Dehalococcoides sp. BAV1 Length = 265 Score = 83.4 bits (197), Expect = 4e-15 Identities = 56/187 (29%), Positives = 90/187 (48%), Gaps = 8/187 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDVDI 217 +GK +VT L AGA+I+ + +E ++ + D+ Sbjct: 11 RGKVAIVTGGAMGIGKGISMRLAEAGASIMIPDLNLEVAQKTVAEIKALGGKATAIQADV 70 Query: 218 GDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + T+KV+++ G D +VNNA + P +D + + +DKT +N+K ++ SQ Sbjct: 71 SNINDTQKVIDATLKAFGDLDIMVNNAGIYRFMPAIDMTEAMWDKTLGINLKGLMFFSQA 130 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 A+ M+ K G I+NI+S + Y ASK + LT+AMA E P+GI VNA+ Sbjct: 131 AAKAMMAAKHGGKIINIASIDGFRPTGNLAHYDASKGGVIMLTKAMAQEWAPHGILVNAV 190 Query: 566 NPTVIMT 586 P I T Sbjct: 191 APGGINT 197 >UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep: Oxidoreductase - Streptomyces echinatus Length = 295 Score = 83.4 bits (197), Expect = 4e-15 Identities = 56/186 (30%), Positives = 86/186 (46%), Gaps = 6/186 (3%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI----GD 223 + ++VT GA ++ + RT LE +P I + DI G Sbjct: 51 RAVVVTGGGTGIGRAVAHRFAEEGARVLVVGRTPGTLEETARHHPGIRALPADITAPDGP 110 Query: 224 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 403 +E G D LVNNAA+ + P++ D N++A + +++ + Sbjct: 111 DTVVSAALERFGRIDVLVNNAALGIAGTLDTLDPADLDAQLATNLRAPMLLTRRALPAL- 169 Query: 404 ENKTHGAIVNISSQAS--KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 K+ G +VN+S+ S + A ++Y A+K ALD LTR A+EL P GIRV + P V Sbjct: 170 -EKSSGTVVNLSTAGSLGRRAWPGMSVYGATKTALDFLTRTWAVELAPRGIRVVGLAPGV 228 Query: 578 IMTEMA 595 I T MA Sbjct: 229 IDTGMA 234 >UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep: Short chain dehydrogenase - Mycobacterium avium (strain 104) Length = 594 Score = 83.4 bits (197), Expect = 4e-15 Identities = 56/192 (29%), Positives = 93/192 (48%), Gaps = 9/192 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGAN-IVALSRTRSHLE----SLQSEYPSIDIVDVD 214 +G+ LVT EL R GA +V + R R+ + ++++ + VD Sbjct: 324 RGRLALVTGAGAGIGRATAVELARQGARKVVIVDRDRAAADQTADAVRAAGAGAAVYQVD 383 Query: 215 IGDW----EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 + D + +V G D LVNNA + + FL+ SP+N+D VNV+ V+ S+ Sbjct: 384 VSDEAAMNDLAAQVRNEHGVVDILVNNAGIGMAGRFLETSPANWDAIMGVNVRGVIWGSR 443 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 +M+E G I+N++S A+ K Y +KAA+ AL+ ++ + GI V A Sbjct: 444 AFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESLRADFADEGITVTA 503 Query: 563 INPTVIMTEMAK 598 + P + T +AK Sbjct: 504 VCPGFVNTNIAK 515 >UniRef50_A6RBN3 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 407 Score = 83.4 bits (197), Expect = 4e-15 Identities = 59/190 (31%), Positives = 93/190 (48%), Gaps = 9/190 (4%) Frame = +2 Query: 38 EISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALS--RTRSHLESLQSEYPS-IDIVD 208 ++S GK ++T + G+++ L + +E LQS+Y + I Sbjct: 155 KLSLDGKVTVITGGSRGIGLALVEAMAGLGSDVAILDIMEPQVDIEKLQSQYSTHIKHFK 214 Query: 209 VDI---GDWEKT-RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 376 D+ G E + LGH D V A +A+ +PFL+ + DVNV Sbjct: 215 TDVTQKGSLENAFSAATKELGHIDNCVTAAGLALDKPFLEYGWEESRRILDVNVIGSFFS 274 Query: 377 SQVVARKMIENKTHGAIVNISSQASKAALKDH--TIYSASKAALDALTRAMALELGPYGI 550 +Q+ AR+M+E G+IV ISS A A+ +IY ASKAA+ L +A+ +E+ P+ I Sbjct: 275 AQLAARQMMEQGNGGSIVMISSMAGHCAMPSQRVSIYGASKAAIKLLGKALGVEMAPHNI 334 Query: 551 RVNAINPTVI 580 RVN ++P I Sbjct: 335 RVNTLSPGYI 344 >UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=123; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia conorii Length = 241 Score = 83.4 bits (197), Expect = 4e-15 Identities = 51/185 (27%), Positives = 88/185 (47%), Gaps = 1/185 (0%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV-DI 217 I GK L+T L + G++++ L+SL ++V ++ Sbjct: 2 IDLTGKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLQSLGKVVKDNYTIEVCNL 61 Query: 218 GDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 D E+ R ++ D LV NA + + +FDK D+N+KA +++ +K Sbjct: 62 ADKEECRNLISKASKLDILVCNAGITSDTLAIRMKDEDFDKVIDINLKANFILNREAIKK 121 Query: 398 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 577 MI+N+ +G I+NISS + Y ASKA L +T++++ E+ GI VN + P Sbjct: 122 MIQNR-YGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNTVAPGF 180 Query: 578 IMTEM 592 I ++M Sbjct: 181 IKSDM 185 >UniRef50_Q1GX18 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingopyxis alaskensis|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 283 Score = 83.0 bits (196), Expect = 6e-15 Identities = 51/166 (30%), Positives = 81/166 (48%), Gaps = 6/166 (3%) Frame = +2 Query: 125 GANIVALSRTRSHLESLQSEYPS------IDIVDVDIGDWEKTRKVVESLGHFDALVNNA 286 G N+VA +R + LE L + Y +D+ D + G + R+ V+ G D L+NNA Sbjct: 26 GHNVVATARNPAVLEDLAARYSGQLLAVRLDVTDAE-GARDAVRQAVDKFGRLDVLINNA 84 Query: 287 AVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALK 466 + D + N +N+++ V M + G I+ +SS ++ A Sbjct: 85 GFSGVGSIEDMPLELIEAQLSTNFLGAVNLTRAVLPTM-RARARGRILLVSSIGARIATA 143 Query: 467 DHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVG 604 +Y ASKAA+ AL +ALE+GP GI+V A+ P + T A+ G Sbjct: 144 GAGVYYASKAAVSALAETLALEVGPLGIQVTAVEPGAMRTRFAEAG 189 >UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1 Length = 263 Score = 83.0 bits (196), Expect = 6e-15 Identities = 56/194 (28%), Positives = 90/194 (46%), Gaps = 8/194 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRT----RSHLESLQSEYPSIDIVDVDI 217 K K LVT L GA +VA +R R + +Q++ V D+ Sbjct: 5 KDKVALVTGASSGIGWATALTLAAEGAKVVACARREDKGRELIALIQAQGGQATWVTADV 64 Query: 218 GDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 +V++ G D NNA ++ +PF++ + +D NV++ + Sbjct: 65 LSERDVEAMVQAALTTYGRLDGAFNNAGTSLSKPFIEMTNDEYDTVMATNVRSAFWCMKY 124 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 + M+ GAIVN +S ++ A+ + YSASKA L ALTR +A+E IR N + Sbjct: 125 QLKAMLAGGG-GAIVNCASVSAVRAMPGLSAYSASKAGLAALTRGVAVEYAQKNIRANTV 183 Query: 566 NPTVIMTEMAKVGW 607 +P ++ +EMA GW Sbjct: 184 SPGIVESEMATAGW 197 >UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Firmicutes|Rep: Amino acid adenylation domain - Bacillus cereus subsp. cytotoxis NVH 391-98 Length = 2031 Score = 83.0 bits (196), Expect = 6e-15 Identities = 53/188 (28%), Positives = 92/188 (48%), Gaps = 8/188 (4%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI----VDVDIGD 223 K +VT + + GA++ +SRT L+ E + I + DIG+ Sbjct: 1786 KVAIVTGGGRGIGRAIAISMAQEGASVAIVSRTEHQLDETACEIRKLGIEPLVIPGDIGE 1845 Query: 224 WEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 W + +V+++ G D +VNNA + D + + + VNV ++ + Sbjct: 1846 WNDVQHIVKTVSKQFGKIDIVVNNAGITKVGSVTDVTSEEWKEIIRVNVFGTYHMCRATI 1905 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 +IE K G I+NI S +S + Y+ASK + LT+++A E+ PY I+VNA+ P Sbjct: 1906 PYLIEQKC-GKIINIGSDSSFIGYPFMSAYAASKHGVLGLTKSLAEEMKPYNIQVNAVCP 1964 Query: 572 TVIMTEMA 595 +++ T+MA Sbjct: 1965 SLVNTDMA 1972 >UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR; n=30; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Acidovorax sp. (strain JS42) Length = 257 Score = 83.0 bits (196), Expect = 6e-15 Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 9/193 (4%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 214 M F GK++LV + G N+V + E + E ++ V Sbjct: 1 MSNQFSGKKLLVVGGTSGMGKETARLVLAQGGNVVIVGNRPEKTEEARKELAALGQVSAL 60 Query: 215 IGDWEKTRKVV-------ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 + K V E D LVN A V +PFL+ S +++D+ +N KA Sbjct: 61 TANLTKDEDVAALLKAIDEQHPDIDLLVNAAGVFFPKPFLEHSDADYDQYMKLN-KAFFF 119 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALK--DHTIYSASKAALDALTRAMALELGPYG 547 I+Q VA + GAIVNI S +K A+ + YS +KA L +LT+ +A+EL P Sbjct: 120 ITQKVAGNLAAKGKPGAIVNIGSMWAKQAIAATPSSAYSMAKAGLHSLTQHLAMELAPKH 179 Query: 548 IRVNAINPTVIMT 586 IRVNA++P V+ T Sbjct: 180 IRVNAVSPAVVET 192 >UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sp. (strain ANA-3) Length = 253 Score = 83.0 bits (196), Expect = 6e-15 Identities = 56/188 (29%), Positives = 93/188 (49%), Gaps = 7/188 (3%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIV--DVDIGDWE 229 K +VT +L GA +VA + L+ +++P+ +V VD+ D++ Sbjct: 6 KTAVVTGAAGGIGQAIIRKLLAEGARVVAADLSADALKVF-NDFPADKLVTFSVDVTDYK 64 Query: 230 KTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSN-FDKTFDVNVKAVLNISQVVAR 394 + +V + G D L+NNA + + +P L P N F+ +VN K V + R Sbjct: 65 QVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGILAGGR 124 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 + + G I+N SS ++ A + Y+ SKAA+D +T+ ALEL P G+RV A+ P Sbjct: 125 QFQAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAALELAPLGVRVCAVAPG 184 Query: 575 VIMTEMAK 598 + T M + Sbjct: 185 RVDTPMLR 192 >UniRef50_A7RXH2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 256 Score = 83.0 bits (196), Expect = 6e-15 Identities = 45/110 (40%), Positives = 64/110 (58%), Gaps = 1/110 (0%) Frame = +2 Query: 272 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK-THGAIVNISSQA 448 LVN+A +A L +FD DVN+K + Q A+ M+ENK +G+I+NISS Sbjct: 94 LVNSAGIAKDALLLKMKEQDFDDVIDVNLKGTFLMCQTTAKAMVENKINNGSIINISSIV 153 Query: 449 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 +K+ Y+ASKA ++ LT+ A+EL +GIR NAI P I T M + Sbjct: 154 AKSGNMGQANYAASKAGVEGLTKVCAIELARFGIRCNAILPGFIDTPMTR 203 >UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6; Pseudomonas aeruginosa|Rep: Probable short-chain dehydrogenase - Pseudomonas aeruginosa Length = 252 Score = 82.6 bits (195), Expect = 7e-15 Identities = 58/181 (32%), Positives = 88/181 (48%), Gaps = 4/181 (2%) Frame = +2 Query: 62 ILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP--SIDIVDVDIGDWEKT 235 +L+T ++ I A + L +L ++ P + + D+ D T Sbjct: 6 VLITGAAGGLGRAIAKRFAQSHWRIAATDVDKEGLHALNAQVPLDASGVADLRSADNCHT 65 Query: 236 --RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN 409 K++ G DALVN A V P + + +FD VN+KA + Q + EN Sbjct: 66 LMSKILARTGRLDALVNAAGVWREGPVENFTEEDFDLVLGVNLKASFYMCQAAIPYLKEN 125 Query: 410 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 589 + G+IVNISS + + A + Y ASKAAL L++ +ALEL G+RVNA++P I T Sbjct: 126 Q--GSIVNISSDSGRQAYRGSAAYCASKAALTMLSKTLALELAEQGVRVNAVSPADIATP 183 Query: 590 M 592 M Sbjct: 184 M 184 >UniRef50_Q46NM9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 263 Score = 82.6 bits (195), Expect = 7e-15 Identities = 57/189 (30%), Positives = 88/189 (46%), Gaps = 8/189 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----IVDVDI 217 +GK LVT L RAG +V R E+L ++ +V +D+ Sbjct: 16 EGKVALVTGAFGGLGLHFARTLARAGCGVVLAGRRVGEGEALLADLRKQGGQGCVVALDV 75 Query: 218 GDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 D E+ LG +VN+A +A +D + + + D N+ ++Q Sbjct: 76 RDPASVDAAFEAARRELGPVQIVVNSAGIATTGAAMDVTEAQWQSVIDTNLNGAWRVAQR 135 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 AR M + THG+I+NI+S + Y+A+KA L LTR++ALE +GIRVNA+ Sbjct: 136 AARMMRDTDTHGSIINIASILGLRVAQQVPAYTAAKAGLIHLTRSLALEWARHGIRVNAL 195 Query: 566 NPTVIMTEM 592 P TE+ Sbjct: 196 APGYFETEI 204 >UniRef50_Q01ZR5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR precursor - Solibacter usitatus (strain Ellin6076) Length = 253 Score = 82.6 bits (195), Expect = 7e-15 Identities = 41/110 (37%), Positives = 66/110 (60%) Frame = +2 Query: 242 VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHG 421 ++E GH D LVN A V PF + S + + + D+++K+V QV ++M++ G Sbjct: 77 ILERFGHVDILVNAAGVNSGTPFFEISETEWQRIMDIDLKSVFLACQVFGKQMVDAAHGG 136 Query: 422 AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 +I+NISS +S L Y+ +KA ++ +T+ +A EL P+ IRVNAI P Sbjct: 137 SIINISSASSGPPLSKVFTYAVAKAGVNQITQYLARELAPHSIRVNAILP 186 >UniRef50_A5VE52 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 267 Score = 82.6 bits (195), Expect = 7e-15 Identities = 51/182 (28%), Positives = 83/182 (45%), Gaps = 8/182 (4%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVDVD 214 +GK +L+ +GANIV +R E + + +V VD Sbjct: 7 EGKNVLLIGGHSNLGQHVTWHFAESGANIVIGARDLDRAEKVAERARELGAGKVSVVSVD 66 Query: 215 IGDWEKTRKVVES---LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 DW +E+ +G D L + A + FLD P +DK ++ N K+VL ++ Sbjct: 67 ATDWSSVANAIEATRAMGSIDILYHGVAWDILSHFLDLDPQLWDKIYEQNFKSVLTAYKI 126 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 V MIE K G ++ +SS + +Y A KA L L + +AL++G +G+R+N + Sbjct: 127 VLPIMIEQK-GGCVITMSSVMGRKPTPIEPVYGALKAGLIHLAQTLALDVGRHGVRINVV 185 Query: 566 NP 571 P Sbjct: 186 AP 187 >UniRef50_A5UT09 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Roseiflexus|Rep: Short-chain dehydrogenase/reductase SDR precursor - Roseiflexus sp. RS-1 Length = 257 Score = 82.6 bits (195), Expect = 7e-15 Identities = 58/189 (30%), Positives = 85/189 (44%), Gaps = 6/189 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALS----RTRSHLESLQSEYPSIDIVDVD-I 217 GK L+T L R GA +V R + ++ + V D I Sbjct: 7 GKVALITGAASGIGRATALTLAREGAAVVVADIDAPRGAETVATIGAAGGRAHFVQADVI 66 Query: 218 GDWEK-TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 394 D E+ ++ G D LVNNA + LD + + + DV SQ AR Sbjct: 67 RDAERMVEAAMQEFGRLDILVNNAGIFYTVDLLDVTFDEWVRAVDVMYFGTFRCSQAAAR 126 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 +M+ G IVNISS + + + Y+++K A+D LTR +A+EL P+GI VN + P Sbjct: 127 QMVHQGAGGRIVNISSINAFLGMPQSSHYNSAKGAIDQLTRCLAVELAPHGILVNGVAPG 186 Query: 575 VIMTEMAKV 601 + T MA V Sbjct: 187 FVETPMAIV 195 >UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p - Drosophila melanogaster (Fruit fly) Length = 269 Score = 82.6 bits (195), Expect = 7e-15 Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 9/200 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID-----IV 205 ++F GK +L+T + + GA + R +L+ + +E + +V Sbjct: 14 MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALV 73 Query: 206 DVDIGDWEKTRKV----VESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 DI T+++ ++ G D LVNNA + S +D+ + N++A+ + Sbjct: 74 VGDIAKEADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYH 133 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 ++ + +++ KT G IVN+SS + Y+ SK +D TR +ALEL G+R Sbjct: 134 LTMLATPELV--KTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVR 191 Query: 554 VNAINPTVIMTEMAKVGWSD 613 VN +NP V +T + G D Sbjct: 192 VNCVNPGVTVTNLHARGGMD 211 >UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 253 Score = 82.6 bits (195), Expect = 7e-15 Identities = 62/198 (31%), Positives = 101/198 (51%), Gaps = 11/198 (5%) Frame = +2 Query: 56 KRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID---IVDVDIGDW 226 K +VT + GA ++ ++R LE+ + E + D + D+ D Sbjct: 6 KVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGLENTRKEIGNEDSTAAMTCDLVDE 65 Query: 227 EKTRKVVESL----GHFDALVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQVV 388 +T +VV + G D LVNNA A+ +P F + S K +VN+ V N+++ V Sbjct: 66 SQTLQVVNQIMDTYGKIDILVNNAG-AINDPIHFHEMQNSEIQKLINVNLLGVFNMTKAV 124 Query: 389 ARKMIENKTHGAIVNISSQASKAAL-KDH-TIYSASKAALDALTRAMALELGPYGIRVNA 562 KM + K+ G+IVNI S +S+ A+ + H +YSA+KAA+ T+++A+E IR N Sbjct: 125 LTKMADVKS-GSIVNIGSISSERAIPRVHLAVYSATKAAIPMFTKSIAVEYARRNIRCNC 183 Query: 563 INPTVIMTEMAKVGWSDP 616 +NP +I + K DP Sbjct: 184 VNPGIINSGSIKPYLDDP 201 >UniRef50_UPI000038E4B9 Cluster: hypothetical protein Faci_03000502; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03000502 - Ferroplasma acidarmanus fer1 Length = 253 Score = 82.2 bits (194), Expect = 1e-14 Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 9/193 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIV--------ALSRTRSHLESLQSEYPSI 196 + F+ K +VT L GAN++ A T ++ S Sbjct: 1 MDFRNKNAIVTGGSRGIGNGIAKALADNGANVIITYGNNDNAADETVKYIRSKGVSGEKY 60 Query: 197 DIVDVDIGDWEKTRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 I DIG+ + K + + D LVNNA + F + + F+K + VNV++ Sbjct: 61 KIDQSDIGEIDGLMKFIKDKFKTVDVLVNNAGICPFMDFFNIDQNLFEKVWKVNVESHFF 120 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 I+Q V++ MIEN T G I+ ISS ++ K Y+ +K+A++ L ++A+ LG +GI Sbjct: 121 ITQRVSQMMIENNTKGKILFISSISAIVGGKFQAHYTTTKSAMNGLMHSLAIILGEHGIM 180 Query: 554 VNAINPTVIMTEM 592 VN++ P I+T++ Sbjct: 181 VNSLEPGTILTDI 193 >UniRef50_Q83BJ4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=4; Coxiella burnetii|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Coxiella burnetii Length = 230 Score = 82.2 bits (194), Expect = 1e-14 Identities = 44/114 (38%), Positives = 66/114 (57%) Frame = +2 Query: 257 GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNI 436 G D LVNNA V F D + F++ +VN+K ++Q VA+ MI + G+I+NI Sbjct: 60 GSIDILVNNAGVGSRAAFTDVTEEQFNQAINVNLKGPFFLTQAVAKHMIAHSKTGSIINI 119 Query: 437 SSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 SS +S A + + Y +KA LT++ AL L P+ IRVN I+P + T+M + Sbjct: 120 SSISSFKAELNISAYECAKAGESMLTKSAALALAPHHIRVNTISPGLTATDMTQ 173 >UniRef50_Q2T2R4 Cluster: Polyketide synthase, putative; n=1; Burkholderia thailandensis E264|Rep: Polyketide synthase, putative - Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 /CIP 106301) Length = 2137 Score = 82.2 bits (194), Expect = 1e-14 Identities = 55/190 (28%), Positives = 92/190 (48%), Gaps = 9/190 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIV-----ALSRTRSHLESLQSEYPSIDIVDVDI 217 GKR+LVT GA+++ +L ++ L++ ++D+V + Sbjct: 8 GKRVLVTGGAKNVGKAICRRFAEEGAHVIVNFFHSLDASKETAAELRALGATVDVVRASV 67 Query: 218 GDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + ++ + + G D LVNNAA P D ++FD+ D N+K ++ Sbjct: 68 AQPAQVERMFDEIEAKYGKLDILVNNAASGALLPVDDIEAAHFDRALDTNLKGAFWCARR 127 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 AR M GAIVN+SS S ++ + +KAAL++LTR +A+E GIRVN Sbjct: 128 AARLMAR-AGGGAIVNVSSVGSTLVPANYLVVGTAKAALESLTRYLAVEYASLGIRVNGA 186 Query: 566 NPTVIMTEMA 595 + T+I ++A Sbjct: 187 SSTLIDGDVA 196 >UniRef50_Q3E250 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Chloroflexus aurantiacus J-10-fl|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aurantiacus J-10-fl Length = 246 Score = 82.2 bits (194), Expect = 1e-14 Identities = 57/190 (30%), Positives = 88/190 (46%), Gaps = 6/190 (3%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID--IVDVDIGD 223 +G+ +VT GA + L R + + + + + + DV I Sbjct: 5 RGRTAIVTGAGRGIGYAIATAFVEHGAQVALLDRDAAVVPAAERLGDRVQGVVADVAIAA 64 Query: 224 WEKT--RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 397 T V+ G D LVNNAAV PFLD +P+ +++T VN+ A+ + + V Sbjct: 65 EVDTAVNHVLHQWGRIDILVNNAAVLSSAPFLDLTPAEWERTLAVNLTAIYHTCRAVVPA 124 Query: 398 MIENKTHGAIVNISSQASK--AALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 MI +G ++ I+S A K + YSA+KA LT+A+A EL P+GI N I P Sbjct: 125 MIAT-GYGRLITIASVAGKRGGGILGSAAYSAAKAGAIGLTKALARELAPHGITANTICP 183 Query: 572 TVIMTEMAKV 601 + T + V Sbjct: 184 GPVETTLLSV 193 >UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB18|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB18) Length = 254 Score = 82.2 bits (194), Expect = 1e-14 Identities = 65/189 (34%), Positives = 87/189 (46%), Gaps = 9/189 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES-LQSEYPSIDIVDV----DI 217 GK +LVT AG + SR+ S + + +E ++ + DI Sbjct: 14 GKVVLVTGGARGIGAGVARRFAGAGCRVAIASRSASPAAAAVLAEIEALGAQGIAVAGDI 73 Query: 218 GDWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + E R +VV G D LVN A VA F + F TFD NV + + Q Sbjct: 74 SNSEDARAMVGEVVARFGRIDVLVNCAGVAEYRAFEATDLAMFRATFDTNVFGTVAMIQA 133 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 + G I+N SS + + +IY+ASKAA+ ALT A+A E GP GI VNAI Sbjct: 134 ALPHL--TAPGGRIINFSSALATRPIPTASIYAASKAAVSALTHALAKEFGPRGITVNAI 191 Query: 566 NPTVIMTEM 592 P VI TEM Sbjct: 192 APGVIETEM 200 >UniRef50_Q1WVR8 Cluster: Short chain dehydrogenase; n=1; Lactobacillus salivarius subsp. salivarius UCC118|Rep: Short chain dehydrogenase - Lactobacillus salivarius subsp. salivarius (strain UCC118) Length = 282 Score = 82.2 bits (194), Expect = 1e-14 Identities = 43/117 (36%), Positives = 68/117 (58%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 +V+ G D LVNNA A+ F D + FDVNV +++++Q V +M + K+ Sbjct: 73 EVIAKFGRIDVLVNNAGYAILGAFEDMDMAEVRTNFDVNVFGLMSMTQAVLPQMRKQKS- 131 Query: 419 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 589 G I+N+SS + +IYSASKAA+ ++ A+A E+ PY I+V A+ P + T+ Sbjct: 132 GRIINLSSISGSVTGPSQSIYSASKAAVTLMSEALAQEVAPYNIKVTALCPWGVRTD 188 >UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Marinomonas sp. MED121|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Marinomonas sp. MED121 Length = 259 Score = 82.2 bits (194), Expect = 1e-14 Identities = 51/155 (32%), Positives = 82/155 (52%) Frame = +2 Query: 173 LQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDV 352 +++ + +D+ D+++ +K + +E+ G ALVNNAA + S FD+ V Sbjct: 66 MKAHFELVDLTDIEMLK-DKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAV 124 Query: 353 NVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE 532 N+K +Q VA M E G+I+N+SS + L + Y +KA + LT+A+A E Sbjct: 125 NLKHHFFAAQKVAPLMAE-AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALARE 183 Query: 533 LGPYGIRVNAINPTVIMTEMAKVGWSDPIKANEML 637 LGP +RVN + P +MTE K W P E++ Sbjct: 184 LGPTKVRVNTVLPGWVMTEKQKALWLTPEAEVELM 218 >UniRef50_A1SMM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nocardioides sp. JS614|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 276 Score = 82.2 bits (194), Expect = 1e-14 Identities = 60/191 (31%), Positives = 86/191 (45%), Gaps = 4/191 (2%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI---V 205 M G I+VT R GA++ E + + Y + + Sbjct: 1 MSRQISGMSIIVTGGARGIGRATVERFARQGASVAIGDLDAELAEEVAAAYGDRVVAARL 60 Query: 206 DV-DIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 DV D W + V LG +D LVNNA + L F+VNV +N ++ Sbjct: 61 DVTDPASWREFLGEVAHLGPWDVLVNNAGIMPLGSVLKEPDEVTRAIFNVNVHGPINGTK 120 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 VA M E + HG IVN++S + A+ D YSASK A+ + A ELGP GI V+ Sbjct: 121 AVAPGMAE-RGHGHIVNVASAVGRLAVADGASYSASKFAVVGFSEATRAELGPLGIDVSL 179 Query: 563 INPTVIMTEMA 595 + PTV+ TE++ Sbjct: 180 VLPTVVQTELS 190 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 82.2 bits (194), Expect = 1e-14 Identities = 47/125 (37%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = +2 Query: 266 DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH-GAIVNISS 442 DALVNNA + +P D S +D+ F++NV++V ++ V M K H G IVN+SS Sbjct: 85 DALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEPM--RKAHKGCIVNVSS 142 Query: 443 QASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIK 622 Y ASK A+ T+A A++L P+ IRVN+++P VI T M + P Sbjct: 143 IYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVIATPMTQQILDAPQS 202 Query: 623 ANEML 637 A +L Sbjct: 203 ARALL 207 >UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cellular organisms|Rep: Acetoin(diacetyl) reductase - Klebsiella pneumoniae Length = 256 Score = 82.2 bits (194), Expect = 1e-14 Identities = 48/134 (35%), Positives = 68/134 (50%), Gaps = 4/134 (2%) Frame = +2 Query: 203 VDVDIGDWEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 V VD+ D ++ VE +LG FD +VNNA VA P +P DK +++NVK V+ Sbjct: 56 VKVDVSDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVI 115 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 Q + G I+N SQA + +YS+SK A+ LT+ A +L P GI Sbjct: 116 WGIQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGI 175 Query: 551 RVNAINPTVIMTEM 592 VN P ++ T M Sbjct: 176 TVNGYCPGIVKTPM 189 >UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chain dehydrogenase; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to short-chain dehydrogenase - Strongylocentrotus purpuratus Length = 269 Score = 81.8 bits (193), Expect = 1e-14 Identities = 56/194 (28%), Positives = 89/194 (45%), Gaps = 12/194 (6%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDI-------V 205 F GK +L+T GA + + R LE + + + + Sbjct: 4 FVGKVVLITGASSGIGAETAVHFAAEGAGLALVGRDEGRLEKTAQDCMAKGLAKDKVLTI 63 Query: 206 DVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFL-DCSPSNFDKTFDVNVKAVL 370 D+ E +++VES G D LVNNA A + + NFD +NV++V+ Sbjct: 64 KADMCVEEDVKRIVESTITYFGRLDVLVNNAGQAKLDLLRSETVMENFDDLLKLNVRSVV 123 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 ++ + +I +K G++VN+SS A K Y+ +AA D TR A++L P G+ Sbjct: 124 QLTNLAVPHLITSK--GSVVNVSSLAGKRVAHMSFSYNILRAATDQFTRCCAVDLAPKGV 181 Query: 551 RVNAINPTVIMTEM 592 RVNA+NP I T + Sbjct: 182 RVNAVNPGAIKTPL 195 >UniRef50_P73991 Cluster: Short-chain alcohol dehydrogenase family; n=2; Cyanobacteria|Rep: Short-chain alcohol dehydrogenase family - Synechocystis sp. (strain PCC 6803) Length = 249 Score = 81.8 bits (193), Expect = 1e-14 Identities = 45/114 (39%), Positives = 70/114 (61%) Frame = +2 Query: 269 ALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 448 +L+NN A+ +C+P L+ S ++D+ VN++A ++++ + +THG+IVNISS Sbjct: 73 SLINNVALQICQPILETSLDDWDQVMAVNLRAAFLLAKMSHPYL--QQTHGSIVNISSVH 130 Query: 449 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWS 610 + A + Y+ASK L ALTRAMA+E IRVNA+ P + T M + G S Sbjct: 131 ALATSANIASYAASKGGLIALTRAMAIEWAADQIRVNALLPGAVNTPMLREGLS 184 >UniRef50_Q1YRW1 Cluster: Pteridine reductase; n=1; gamma proteobacterium HTCC2207|Rep: Pteridine reductase - gamma proteobacterium HTCC2207 Length = 248 Score = 81.8 bits (193), Expect = 1e-14 Identities = 43/124 (34%), Positives = 75/124 (60%) Frame = +2 Query: 212 DIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 D+ EK ++V S+G D L+NNA+ P C+ +D + N+K ++Q +A Sbjct: 69 DMAGIEKIIQLVGSIGRLDVLINNASSFYPTPLEQCTNEQWDDLINSNLKGPFFLTQGLA 128 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 ++I + G++VNIS ++ AL DH IY+ +KA A+T++MAL++ P+ +RVN++ P Sbjct: 129 PQLIAAR--GSVVNISDMHARQALADHPIYTIAKAGNIAMTKSMALDMAPH-VRVNSVAP 185 Query: 572 TVIM 583 I+ Sbjct: 186 GAIL 189 >UniRef50_A6ULD1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 264 Score = 81.8 bits (193), Expect = 1e-14 Identities = 64/201 (31%), Positives = 88/201 (43%), Gaps = 9/201 (4%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESL-----QSEYPSIDIV 205 I GK IL T RAGA +VA+ +ESL + + + Sbjct: 15 ICIAGKVILYTGAAGGLGTATTLSFLRAGAKVVAIDNNPEKVESLIAAAARENLQGLTVR 74 Query: 206 DVDIGDWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 +D+ D + R +V +G FD ++NNAA+ + F D + F VNV A + Sbjct: 75 ALDLSDLKGLRVELDRVSAEVGGFDIVINNAAIYPSKNFEDYTIEEFQAVQCVNVDAGIV 134 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 Q M + G IVNI+S Y SK AL LTRA A E G YG+ Sbjct: 135 CVQAALSHM-RAQGWGRIVNIASVTVYGGWSHLAPYVQSKGALVGLTRAWAREFGAYGVT 193 Query: 554 VNAINPTVIMTEMAKVGWSDP 616 VNA++P T+ K+ SDP Sbjct: 194 VNAVSPGAFPTDAEKI-HSDP 213 >UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 253 Score = 81.8 bits (193), Expect = 1e-14 Identities = 55/186 (29%), Positives = 90/186 (48%), Gaps = 5/186 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-PSIDIVDVDIG 220 +++GK+ ++ L GA ++ R+ S++ ++ E+ P + + DI Sbjct: 3 NYQGKKAIIVGGTHGMGLATVRRLVEGGAEVLLTGRSESNIARIREEFGPRVHALSSDIA 62 Query: 221 DWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 + LG D L NA ++ EPF S +++D+ F VN K Q + Sbjct: 63 HLNDIAILGAAAGQKLGAIDLLHINAGISELEPFDQVSEASYDRQFSVNTKGAFFTVQRL 122 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 A + E G+IV SS A + + ++YSASKAAL + +A EL P GIRVN+++ Sbjct: 123 APLIREG---GSIVFTSSVADEGGHQGMSVYSASKAALVSFASVLAAELLPRGIRVNSVS 179 Query: 569 PTVIMT 586 P I T Sbjct: 180 PGFIDT 185 >UniRef50_A3SDF7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sulfitobacter sp. EE-36|Rep: Short-chain dehydrogenase/reductase SDR - Sulfitobacter sp. EE-36 Length = 253 Score = 81.8 bits (193), Expect = 1e-14 Identities = 54/191 (28%), Positives = 89/191 (46%), Gaps = 5/191 (2%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPSIDI 202 + I R LVT L GA++V +R LE L++ + + Sbjct: 5 LSIDLSQSRALVTGASSGLGAHFASVLAAQGADLVLAARRTDKLEEVAAPLRAMGRDVHV 64 Query: 203 VDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 382 V +D+G E + + ++NN+ + D + + DVN+ V +S+ Sbjct: 65 VQMDVGSPEAVEAAFADMPPCEIVINNSGIGQNSWLADMDEDEWQQLIDVNLSGVWRVSK 124 Query: 383 VVARKMIENKTHGAIVNISS-QASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 + KT GAIVNI+S AS+ ALK Y+ +KA + +T+++A+E+ GIRVN Sbjct: 125 QAVAMFRKEKTAGAIVNIASITASRTALKSGA-YAVTKAGVIHMTKSLAIEVARDGIRVN 183 Query: 560 AINPTVIMTEM 592 A+ P TE+ Sbjct: 184 ALAPGYFQTEL 194 >UniRef50_A1ZSH9 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Microscilla marina ATCC 23134|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Microscilla marina ATCC 23134 Length = 246 Score = 81.8 bits (193), Expect = 1e-14 Identities = 54/189 (28%), Positives = 93/189 (49%), Gaps = 3/189 (1%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIV-DVDI 217 + K RIL+T L AGA ++ R L+++ E + + +V + Sbjct: 9 MDIKDARILITGGSAGIGKATAKMLANAGAKVLITGRDEKKLQNVAQELGVMYVAANVAL 68 Query: 218 -GDWEKTRKVVES-LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 D +KT +V + LG D L+NNA + + S +F + ++VNV + ++Q A Sbjct: 69 PADIDKTFDMVNNQLGGLDVLINNAGIGEFPTLEELSLEDFQRVYNVNVFGLALMTQKAA 128 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 + + + G I+NI+S A+ + TIY++SK AL +T EL Y +RV +NP Sbjct: 129 H-LFKEQNSGNIINIASTAATKGFERGTIYASSKFALRGMTECWQAELRRYNVRVILVNP 187 Query: 572 TVIMTEMAK 598 + + T A+ Sbjct: 188 SEVPTAFAQ 196 >UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 247 Score = 81.4 bits (192), Expect = 2e-14 Identities = 45/121 (37%), Positives = 64/121 (52%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 KV+E G D +VNNA + L +D+ DVN+K N+ + ++ MI+ K Sbjct: 76 KVIEEFGSIDVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVIKFASKYMIK-KRK 134 Query: 419 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 G I+NISS Y+ASKA + LT+++A EL GI VNA+ P I T+M Sbjct: 135 GKIINISSVVGLMGNVGQANYAASKAGIIGLTKSVAKELASRGITVNAVAPGFIETDMTN 194 Query: 599 V 601 V Sbjct: 195 V 195 >UniRef50_Q5KZY0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Geobacillus kaustophilus|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Geobacillus kaustophilus Length = 239 Score = 81.4 bits (192), Expect = 2e-14 Identities = 54/184 (29%), Positives = 86/184 (46%), Gaps = 5/184 (2%) Frame = +2 Query: 44 SFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQ-SEYPSIDIVDVDIG 220 + KGK I++T +L + G+N+ SRT + Q S Y ++ + +VD+ Sbjct: 6 ALKGKNIVITGASRGIGYETAKQLAKLGSNLALGSRTIKQMSPEQFSSYGNVFLAEVDVA 65 Query: 221 DWEKTRK----VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 D + VV +LG DAL+N+A V LD FD VN++ + Sbjct: 66 DERSVKDFVCDVVSTLGSVDALINSAGVGTFANVLDSQTDEFDTMISVNLRGTYLCCKHF 125 Query: 389 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 R M+E + G I+N+ S A A+ Y ASK + LT+ + EL G+ V+A+ Sbjct: 126 GRHMVERR-KGRILNMVSVAGVTAIPGCGGYCASKFGVLGLTKVLQSELRAQGVYVSAVI 184 Query: 569 PTVI 580 P + Sbjct: 185 PGAV 188 >UniRef50_Q0SCM6 Cluster: Probable short chain dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Probable short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 238 Score = 81.4 bits (192), Expect = 2e-14 Identities = 63/186 (33%), Positives = 93/186 (50%), Gaps = 6/186 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 232 GK + VT L GA++ AL RT S L E +DI D Sbjct: 6 GKVVAVTGSAGGIGEAVCARLIDEGASVYALDRTASPL----GESTIVDITDPYAMAQVA 61 Query: 233 TRKVVESLGHFDALVNNAAVAVCEPFL---DCSPSNFDKTFDVNVKAVLNISQVVARKMI 403 TR + E G D LV AA V E + + + +D+T VN++ + +Q R+M+ Sbjct: 62 TR-IAEREGRIDGLV--AAAGVVEDDIAAEEMTLDEWDRTLGVNLRGLFITNQAFGRRML 118 Query: 404 ENKTHGAIVNISSQASKAAL---KDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 E K+ GAIVNISS + + + Y+ASKAA+ ALT+++A E G+RVNA++P Sbjct: 119 EQKS-GAIVNISSMSGNHVVNVPQKQCAYNASKAAVTALTKSLASEWADRGVRVNAVSPG 177 Query: 575 VIMTEM 592 + T + Sbjct: 178 YVATPL 183 >UniRef50_Q44MJ4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Chlorobium limicola DSM 245|Rep: Short-chain dehydrogenase/reductase SDR - Chlorobium limicola DSM 245 Length = 257 Score = 81.4 bits (192), Expect = 2e-14 Identities = 56/194 (28%), Positives = 90/194 (46%), Gaps = 8/194 (4%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDV- 211 M+I F K L+T + + GAN++ + ++ L + + +V Sbjct: 8 MKIDFTNKTALITGATRGIGKSVADCMRKEGANLILTGTIKEEVDELNKQMVEKGVNNVI 67 Query: 212 ----DIGDWEKTRKVVESLGHF---DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 D D + + L + D +NNA V F+ F + DVN+KA Sbjct: 68 YYQADFADSKSMDLFLARLREYEKIDICINNAGVNYVNEFIHVKDDEFIRILDVNLKAPY 127 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 I +VVA KMI N+ +G IVNI+S S ++Y+ASK AL LT+ +++E + Sbjct: 128 KILKVVAPKMISNQ-YGKIVNIASIWSVVTRHGRSMYTASKNALVGLTKTLSIEWASKNV 186 Query: 551 RVNAINPTVIMTEM 592 VNA++P TE+ Sbjct: 187 LVNAVSPGFTATEL 200 >UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 264 Score = 81.4 bits (192), Expect = 2e-14 Identities = 58/189 (30%), Positives = 88/189 (46%), Gaps = 9/189 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSH-----LESLQSEYPSIDIVDVDI 217 GK ++T R GA++V S + +E+++++ S + DI Sbjct: 4 GKVAIITGGGTGIGAAIARLFARKGAHVVITSELAAEAMAPVVEAIRADGGSASAMSCDI 63 Query: 218 GDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 D +VE + G D L+ +A V P P D TF VNV +++ Q Sbjct: 64 MDRAAIAALVEGVERDHGRIDILIQSAGVCFAGPIETMEPRKIDLTFGVNVIGAISMIQA 123 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 M + GAIVNISS A+ + + +Y+ASKAA+ TR +A EL IR+NAI Sbjct: 124 ALPAM-KRAGGGAIVNISSGAAVLGVNEMAVYAASKAAIAHFTRTLAPELRRTNIRINAI 182 Query: 566 NPTVIMTEM 592 P + T+M Sbjct: 183 GPGSVRTQM 191 >UniRef50_A1SP95 Cluster: Short-chain dehydrogenase/reductase SDR; n=20; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 270 Score = 81.4 bits (192), Expect = 2e-14 Identities = 63/195 (32%), Positives = 93/195 (47%), Gaps = 10/195 (5%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRT----RSHLESLQSEYPSIDIVDV-DI 217 GK LVT RAGA++V SR R+ E ++ E+ + Sbjct: 22 GKVALVTGGSRGLGRAMVRGFARAGADVVISSRKLDDCRALAEEVEREHGRRAFPHAAHV 81 Query: 218 GDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLD-CSPSNFDKTFDVNVKAVLNISQ 382 G W++ +VE+ G D LVNNA +A P LD + FDK VN+K ++ Sbjct: 82 GHWDEVGALVEAAYAEFGRVDVLVNNAGLAPTYPGLDQVTEELFDKVIGVNLKGPFRLTA 141 Query: 383 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 562 +VA +M G+I+NISS A+ + Y+A+K L+ LT A GP +RVN Sbjct: 142 LVATRMAAG-AGGSIINISSSAAVRPMTTDLPYAAAKGGLNVLTAGFAQAFGP-SVRVNT 199 Query: 563 INPTVIMTEMAKVGW 607 I +T+M++ GW Sbjct: 200 IMAGPFLTDMSR-GW 213 >UniRef50_A0V473 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Delftia acidovorans SPH-1 Length = 307 Score = 81.4 bits (192), Expect = 2e-14 Identities = 49/115 (42%), Positives = 65/115 (56%), Gaps = 1/115 (0%) Frame = +2 Query: 257 GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNI 436 G D LVN+A +A PF+D NF T +VNV L +Q AR M++ + G IVNI Sbjct: 134 GRCDILVNSAGIAKVFPFIDFPLDNFVATMNVNVTGTLLCAQAAARLMVK-QGWGRIVNI 192 Query: 437 SSQASKAAL-KDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 598 +S A A+ T Y SK A+ ALTR MA+EL +GI NA+ P + T M + Sbjct: 193 ASVAGMRAVGSGRTAYGTSKGAVIALTRQMAVELAEHGITANAVAPGPVDTPMTQ 247 >UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specificities; n=3; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 255 Score = 81.4 bits (192), Expect = 2e-14 Identities = 59/198 (29%), Positives = 97/198 (48%), Gaps = 14/198 (7%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIV-------ALSRTRSHLESLQSEYPSID 199 +S KGK LVT L GA + + + S +ESLQ++ Sbjct: 1 MSLKGKIALVTGGARGIGAGIVRALSEQGAKVAFNYVSPSSRAAAGSLVESLQNDGHEAF 60 Query: 200 IVDVDIGDWEKTRKVVESL------GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVK 361 + D+ D + +V ++ D LVNNA P + + ++ K D+NV+ Sbjct: 61 GIQADLADIQAPATLVSAVLSAFQTTQIDILVNNAGAGDNRPLEEVTLESYTKLMDINVR 120 Query: 362 AVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELG- 538 AV+ ++Q V + G I+N+SS +++ ++Y+A+KAA++ LTR A ELG Sbjct: 121 AVVFMTQAVLPYIPRG---GRIINLSSISARGGYPTQSVYAATKAAVEGLTRVWATELGH 177 Query: 539 PYGIRVNAINPTVIMTEM 592 YG+ VNA+NP + T+M Sbjct: 178 KYGVTVNAVNPGPVDTDM 195 >UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductase; n=4; Bacteria|Rep: Short-chain dehydrogenase/oxidoreductase - Lactobacillus plantarum Length = 279 Score = 81.0 bits (191), Expect = 2e-14 Identities = 44/127 (34%), Positives = 70/127 (55%) Frame = +2 Query: 236 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 + V + G D LVN AA+ P D + +VN+ +SQ R MI+ K Sbjct: 80 KAVTDKFGEVDVLVNTAAILRFSPLEDLRLDEWQAALNVNLTGYFLMSQRFGRVMIQQK- 138 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA 595 HGA+V+IS+ AS+ YS +KAA++ +++ MA E G YG+R N + P ++ T ++ Sbjct: 139 HGAMVHISTVASRYPETYSGAYSTTKAAVNMMSKQMAAEWGQYGVRSNCVLPCLVKTPLS 198 Query: 596 KVGWSDP 616 + +SDP Sbjct: 199 ENFYSDP 205 >UniRef50_Q82VC9 Cluster: Short-chain dehydrogenase/reductase (SDR) superfamily; n=7; Proteobacteria|Rep: Short-chain dehydrogenase/reductase (SDR) superfamily - Nitrosomonas europaea Length = 246 Score = 81.0 bits (191), Expect = 2e-14 Identities = 65/188 (34%), Positives = 94/188 (50%), Gaps = 10/188 (5%) Frame = +2 Query: 50 KGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSH-----LESLQSEYP-SIDIVDV 211 K K ILVT L R GA +V R S + L+ +P S+ ++ Sbjct: 2 KDKVILVTGGARRVGAAICRWLHRKGARLVVHYRDSSADAQRLKQELEQGHPDSVALLQA 61 Query: 212 DIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 379 D+ D +V+ G DALVNNA+ P DC+ + N+KA L +S Sbjct: 62 DLLDTGGIPALVDQAARQFGRLDALVNNASSFFPTPVGDCTEQAWHDLVGSNLKAPLFLS 121 Query: 380 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 559 Q VA + +N+ G IVNI ++ LK + IY+A+K L ALTR++A+EL P +RVN Sbjct: 122 QAVAPYLKKNR--GCIVNIIDIHTEQPLKRYVIYNAAKGGLAALTRSLAMELAP-EVRVN 178 Query: 560 AINPTVIM 583 I+P I+ Sbjct: 179 GISPGPIL 186 >UniRef50_Q629N6 Cluster: Putative polyketide synthase; n=11; Burkholderia|Rep: Putative polyketide synthase - Burkholderia mallei (Pseudomonas mallei) Length = 2338 Score = 81.0 bits (191), Expect = 2e-14 Identities = 54/190 (28%), Positives = 92/190 (48%), Gaps = 9/190 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIV-----ALSRTRSHLESLQSEYPSIDIVDVDI 217 GKR+LVT GA+++ +L ++ L++ ++D+V + Sbjct: 8 GKRVLVTGGAKNVGKAICRRFAEEGAHVIINFFHSLDASKQTAAELRALGATVDVVRASV 67 Query: 218 GDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQV 385 + ++ + + G D LVNNAA P D ++FD+ D N+K ++ Sbjct: 68 AQPAQVERMFDEIEAKYGKIDILVNNAASGALLPVDDIEAAHFDRALDTNLKGAFWCARR 127 Query: 386 VARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 565 AR M GAIVN+SS + ++ + +KAAL++LTR +A+E GIRVN Sbjct: 128 AARLMAR-AGGGAIVNVSSVGATLVPANYLVVGTAKAALESLTRYLAVEYASLGIRVNGA 186 Query: 566 NPTVIMTEMA 595 + T+I ++A Sbjct: 187 SSTLIDGDVA 196 >UniRef50_Q840C9 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase DhbA; n=1; Acinetobacter baumannii|Rep: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase DhbA - Acinetobacter baumannii Length = 256 Score = 81.0 bits (191), Expect = 2e-14 Identities = 46/140 (32%), Positives = 76/140 (54%), Gaps = 3/140 (2%) Frame = +2 Query: 203 VDVDIGDWEKTRKVVESL---GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLN 373 + DI + T+ ++ L + LVN A V + L+ P ++ F VNV A + Sbjct: 58 ISQDITQQQTTQNLIAELLEKHNITGLVNAAGVLIMRSMLEAKPEDWQTLFAVNVMAPIA 117 Query: 374 ISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIR 553 ISQ +A+ E K G+IV ISS +++ +Y+ SKAAL R +ALE+ P+ +R Sbjct: 118 ISQQLAKHFCEKK-QGSIVTISSNSARMPRMQLGMYATSKAALSHYCRNLALEIAPHQVR 176 Query: 554 VNAINPTVIMTEMAKVGWSD 613 +N ++P +T+M + W+D Sbjct: 177 LNIVSPGSTLTQMQQQLWTD 196 >UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 524 Score = 81.0 bits (191), Expect = 2e-14 Identities = 45/121 (37%), Positives = 67/121 (55%) Frame = +2 Query: 236 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKT 415 R V G D + NNA + + P LD S D+ VN+K VL Q A ++ ++ Sbjct: 339 RSAVSDHGRVDVMCNNAGIIIDVPVLDLSEEQLDRVLAVNLKGVLFGCQA-AGAVMRSQR 397 Query: 416 HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA 595 G+I+N++S A A YS SKA + +TR +A ELGP G+RVNAI P ++ T++ Sbjct: 398 AGSIINMASGAFDTAPARLVAYSISKAGVVQITRTLAKELGPDGVRVNAIAPGLVETDIT 457 Query: 596 K 598 + Sbjct: 458 R 458 >UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; delta proteobacterium MLMS-1|Rep: Short-chain dehydrogenase/reductase SDR - delta proteobacterium MLMS-1 Length = 275 Score = 81.0 bits (191), Expect = 2e-14 Identities = 59/195 (30%), Positives = 92/195 (47%), Gaps = 10/195 (5%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIV-----ALSRTRSHLESLQSEYPSID 199 ME+ K +LVT L GA +V A + R+ + + Sbjct: 25 MELQLNDKVVLVTGASRGIGAACARALAGCGAAVVVNYMQAEEQARAVAAEINAGGGRAL 84 Query: 200 IVDVDIGDWEKTRKVVES----LGHFDALVNNAAVAV-CEPFLDCSPSNFDKTFDVNVKA 364 + D+ D E K+V++ +G D LVNNA + +PF + + + +KA Sbjct: 85 AIQADVRDREAVEKMVQTAAREMGPIDVLVNNAHINFPIQPFTALAWPDIEAKLTGEIKA 144 Query: 365 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 544 + N SQ V M E K G ++ +SS S++ + +SA+KAALD + R MA ELGP Sbjct: 145 LYNCSQAVLPGMRERKA-GKLILVSSTLSRSPGEGFAAHSAAKAALDGMARGMATELGPE 203 Query: 545 GIRVNAINPTVIMTE 589 GI VN ++P + T+ Sbjct: 204 GITVNVVSPGLTATD 218 >UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; Frankia|Rep: Putative dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 295 Score = 81.0 bits (191), Expect = 2e-14 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 7/180 (3%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESL-QSEYPSIDIVDVDIGDW- 226 G+ L+T AGA + + R ++ ++++ +S P +I+ + Sbjct: 51 GRIALITGGTQGIGLGVAEAFLAAGARVAVVGRDKAKMDAVVESLAPLGEIIGIQADVTV 110 Query: 227 --EKTRKVVESLGHF---DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 391 E R V ++ HF D L A V P LD + +++D FD+NVK +Q A Sbjct: 111 VAEAARIVSATVDHFGGLDILATVAGVFEGAPLLDATEADYDIQFDLNVKGTYFCAQAAA 170 Query: 392 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 571 R +++ G I+ + S A A ++Y A+KAA+ LT+ +A EL P+GI VN + P Sbjct: 171 RHLVDQGRRGKIITVGSVAGLRAFPGVSVYGATKAAVGFLTQVLAGELAPHGINVNCVVP 230 >UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 251 Score = 81.0 bits (191), Expect = 2e-14 Identities = 60/210 (28%), Positives = 94/210 (44%), Gaps = 8/210 (3%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSID----I 202 M K + ++T L G I +SR + L + +E + I Sbjct: 1 MSGKLKDRVAVITGASKGLGKAMAMALAAEGTRIALVSRDEARLNEVAAELIAAGGDAAI 60 Query: 203 VDVDIGDWEKTRK----VVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 D+ E+ R+ ++ + G D L+NNA V V +P ++ + + + D NV A Sbjct: 61 FRADVTSEEQVRQAERAILATYGKVDILINNAGVNVRKPVVEFTVEEWHRVMDTNVTAAF 120 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 + + M + +G I+N++S S +L YS SK AL +TR +ALEL P GI Sbjct: 121 LMCRSFVPAM-SGRGYGRILNMTSIMSHVSLPGRIAYSTSKTALLGMTRTLALELAPQGI 179 Query: 551 RVNAINPTVIMTEMAKVGWSDPIKANEMLS 640 VN I+P TEM K +P + LS Sbjct: 180 TVNGISPGPFGTEMNKPLMENPETNAQFLS 209 >UniRef50_A6UFI1 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 259 Score = 81.0 bits (191), Expect = 2e-14 Identities = 59/200 (29%), Positives = 94/200 (47%), Gaps = 8/200 (4%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPSIDI 202 M +GKRI+VT GA ++ + R LE LQ + + Sbjct: 1 MSARLQGKRIMVTGAAQGIGLAIAEVFLSEGAALLLVDRDGPLLEREASRLQEQGWELVY 60 Query: 203 VDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 DI D + V S +G +ALVNNA + V L S +++ + FDVN++ Sbjct: 61 AQADITDAQAISVAVSSAATSIGRINALVNNAGINVFSEPLAMSDADWQRCFDVNLRGAW 120 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 N + V +IE + GAI+NI+S + + Y +K AL +T+A+ +E G+ Sbjct: 121 NCCKAVLPNLIE-QGGGAILNIASTHAFTIIPHTFPYPVAKHALLGMTKALGIEYASKGV 179 Query: 551 RVNAINPTVIMTEMAKVGWS 610 RVNA+ P ++T+ A W+ Sbjct: 180 RVNALAPGYVLTQKAYDYWN 199 >UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Sphingomonadaceae|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 261 Score = 81.0 bits (191), Expect = 2e-14 Identities = 64/195 (32%), Positives = 87/195 (44%), Gaps = 11/195 (5%) Frame = +2 Query: 35 MEISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI---DIV 205 M GK +VT L GA +V +R LE+ ++E + + V Sbjct: 1 MSQDMTGKVAIVTGGSDGIGLATARLLAARGATVVICARREDKLEAARAEIAKVGKVEAV 60 Query: 206 DVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL- 370 +D+ D +VE + G D LVNNA P ++ K F VN AV Sbjct: 61 KLDVSDEAAFTALVEDVAARHGRLDMLVNNAMSVHYAPIAKLRLDHWRKDFAVNADAVFV 120 Query: 371 ---NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGP 541 +V+A + + GAIVNI+S A + YSASKAA+ T A A+E P Sbjct: 121 GTKAAMKVMAAQEQRGRQRGAIVNIASTCGIRAAPNMASYSASKAAMVHFTAAAAMEGAP 180 Query: 542 YGIRVNAINPTVIMT 586 GIRVNAI P +MT Sbjct: 181 LGIRVNAIVPGQVMT 195 >UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 254 Score = 81.0 bits (191), Expect = 2e-14 Identities = 42/127 (33%), Positives = 70/127 (55%), Gaps = 2/127 (1%) Frame = +2 Query: 221 DWEKTR-KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAV-LNISQVVAR 394 DW+K + + + D L NNA + + +P + S++++ +NV V L + ++ Sbjct: 71 DWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGMKHIMPL 130 Query: 395 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 574 +NK G+++N SS A H +Y ASK A+ +T+ A+E PYG+RVN+I+P Sbjct: 131 MAKQNK--GSVINASSIAGLTGAAGHVLYGASKGAVRIMTKDAAMEYAPYGVRVNSIHPG 188 Query: 575 VIMTEMA 595 I T MA Sbjct: 189 YIDTGMA 195 >UniRef50_A1WDR0 Cluster: Short-chain dehydrogenase/reductase SDR; n=24; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Acidovorax sp. (strain JS42) Length = 236 Score = 81.0 bits (191), Expect = 2e-14 Identities = 58/190 (30%), Positives = 96/190 (50%), Gaps = 6/190 (3%) Frame = +2 Query: 41 ISFKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIG 220 +S K ++VT R IVA SR+ SE P I + DIG Sbjct: 1 MSISHKVVVVTGASQGIGAAVVKAFRRLDYRIVATSRSIK-----PSEDPDILTLAGDIG 55 Query: 221 DWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 388 D ++V+ G D LVNNA + + +PF + + +F +VNV I+Q+ Sbjct: 56 DPATAKRVISEGVAKFGRIDTLVNNAGIYIGKPFTEHTAQDFAAVVNVNVAGFYYITQLA 115 Query: 389 ARKMIENKTHGAIVNISSQASKAALKD-HTIYSA-SKAALDALTRAMALELGPYGIRVNA 562 +M E ++G +V+++S + AA+ +++ +A +K L+A T+++A+E GIRVNA Sbjct: 116 IAEM-EKHSNGHVVSVTSSTADAAIGGVYSVLAALTKGGLNAATKSLAIEYASKGIRVNA 174 Query: 563 INPTVIMTEM 592 + P +I T M Sbjct: 175 VAPGIIRTPM 184 >UniRef50_A1RDP9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Arthrobacter aurescens TC1|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Arthrobacter aurescens (strain TC1) Length = 257 Score = 81.0 bits (191), Expect = 2e-14 Identities = 63/197 (31%), Positives = 91/197 (46%), Gaps = 15/197 (7%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 232 GK VT +L + GA +VAL R + LE L ++P + V +D+ D Sbjct: 6 GKIAAVTGAASGNGLAIAEKLLKEGATVVALDRDEAALERLIGQHPEMVPVVMDVADEAS 65 Query: 233 TR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKM 400 R ++ G D LVNNA + F D S + +D+ F VN +SQ AR + Sbjct: 66 VRSGMAEIDAKFGRLDTLVNNAGIVKGSNFDDVSVAEWDQVFAVNSTGPFLVSQA-ARPL 124 Query: 401 IE-------NKTHGAIVNISSQASKAALKD----HTIYSASKAALDALTRAMALELGPYG 547 +E + + AIVNI+S + + Y+ASK AL T+A+A+E Sbjct: 125 LEKGAAARGDDSTSAIVNITSVEAHIVIASSGHPQVHYNASKGALLMFTKALAIETAASK 184 Query: 548 IRVNAINPTVIMTEMAK 598 IRVNA+ P I T K Sbjct: 185 IRVNAVAPGFIETPFTK 201 >UniRef50_A1HSQ5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Thermosinus carboxydivorans Nor1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Thermosinus carboxydivorans Nor1 Length = 255 Score = 81.0 bits (191), Expect = 2e-14 Identities = 48/168 (28%), Positives = 86/168 (51%), Gaps = 8/168 (4%) Frame = +2 Query: 113 LWRAGANIVALSRTR-------SHLESLQSEYPSIDIVDVDIGDWEKTR-KVVESLGHFD 268 L AGA+++ +SR + + +E+L ++ I + + E+ + ++V G D Sbjct: 29 LAEAGAHVIPVSRNKEKNAALVAKIEALGRRSMTVSIDATNRAEMEQLKDEIVAKFGRVD 88 Query: 269 ALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 448 L+N A V +PFL+ +D +VN+K++ QV M+E + +G I+N SS Sbjct: 89 VLINAAGALVKKPFLEVGEDEWDHVINVNLKSIYTACQVFGPIMLE-QGYGKIINFSSMG 147 Query: 449 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 + + + Y +K ++ LT+ +A E GP G+ VNAI P T + Sbjct: 148 AFLGITRSSAYCTTKGGVNQLTKVLACEWGPKGVNVNAIAPGFFKTPL 195 >UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Burkholderiales|Rep: Short-chain dehydrogenase/reductase SDR precursor - Delftia acidovorans SPH-1 Length = 264 Score = 81.0 bits (191), Expect = 2e-14 Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 8/184 (4%) Frame = +2 Query: 53 GKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 232 G+R+LVT AGA ++ ++ L++L + P D+ D + Sbjct: 9 GQRVLVTAGAAGIGLEISRAFAEAGARVMVCDVAQASLDALAAALPGASGRLADVSDALQ 68 Query: 233 TR---KVVES-LGHFDALVNNAAVAVCEPFLDCSP-SNFDKTFDVNVKAVLNISQVVARK 397 + K V++ LG D LVNNA VA ++ +++ +T DVN+ +++ + Sbjct: 69 VQALFKAVDNELGGLDILVNNAGVAGPTGAVETLDLADWQRTLDVNITGAFLCTRLAVPR 128 Query: 398 MIENKTHG---AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 568 + ++ G AIVN+SS A + + YSASK A+ T+++ALELG GIRVNAI Sbjct: 129 LRQSAREGRQAAIVNLSSAAGHLGMPGRSAYSASKWAVIGFTKSLALELGADGIRVNAIL 188 Query: 569 PTVI 580 P + Sbjct: 189 PGAV 192 >UniRef50_A0QVD4 Cluster: Dehydrogenase/reductase SDR family protein member 10; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Dehydrogenase/reductase SDR family protein member 10 - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 255 Score = 81.0 bits (191), Expect = 2e-14 Identities = 55/196 (28%), Positives = 93/196 (47%), Gaps = 4/196 (2%) Frame = +2 Query: 47 FKGKRILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDW 226 F G+RILVT GA + + + + + S D+ D D Sbjct: 9 FVGRRILVTGGASGVGEACVGYFLGLGATVACIDVKVPARDDAKFVHLSADLRDRDAVS- 67 Query: 227 EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIE 406 ++ E D LVNNA V+ D + ++++ +D+NV + ++ A ++ Sbjct: 68 SAVAEIAERFHGLDTLVNNAGVSFVGTVEDGTEDDWNRLWDINVMGAVRSTRA-ALPLLR 126 Query: 407 NKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP----T 574 AIVN+SS + + ++ Y+A+K A++++TRAMA +L GI VNA+NP T Sbjct: 127 RSDSAAIVNVSSLTATSGIRQRAAYTATKGAIESMTRAMAADLVSEGITVNAVNPGTVDT 186 Query: 575 VIMTEMAKVGWSDPIK 622 M E+A DP++ Sbjct: 187 PFMAELAARA-EDPVQ 201 >UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 355 Score = 81.0 bits (191), Expect = 2e-14 Identities = 50/147 (34%), Positives = 80/147 (54%), Gaps = 3/147 (2%) Frame = +2 Query: 173 LQSEYPSIDIVDVDIGDWEKTRKVVES-LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFD 349 LQ+++ +D+ D + W +T +++ G D L+NNA + V D + +D+ Sbjct: 150 LQADFRFLDVTDAE--QWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVA 207 Query: 350 VNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTI--YSASKAALDALTRAM 523 VN K + Q A +++ +G+I+NI S A + H + YSASK A+ LT+A Sbjct: 208 VNTKGQMLGMQACA-PLMKRSGNGSIINIGSTAG---IMGHPVAAYSASKWAVRGLTKAA 263 Query: 524 ALELGPYGIRVNAINPTVIMTEMAKVG 604 A+EL GIRVNA++P V+ T M G Sbjct: 264 AMELASSGIRVNAMHPGVVETPMVDAG 290 >UniRef50_Q0CBP4 Cluster: Putative uncharacterized protein; n=2; Pezizomycotina|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 276 Score = 81.0 bits (191), Expect = 2e-14 Identities = 41/122 (33%), Positives = 77/122 (63%), Gaps = 2/122 (1%) Frame = +2 Query: 239 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 418 KV+ + G LV A +A+ +PF+D + F + ++NV+ +SQ+VA+ +++ Sbjct: 85 KVLAAFGTVHGLVPAAGIAIDKPFVDQTWDEFTRINEINVRGTFFLSQLVAKHLLKQNQG 144 Query: 419 GAIVNISSQASKAALKDHTI--YSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEM 592 G++V I+SQ++ AL + + Y+ASK + L++A+A+EL P+ IRVN I+P + ++M Sbjct: 145 GSMVLIASQSAHIALPGYRMAAYNASKGGVLMLSKALAVELAPHNIRVNTISPGFVDSDM 204 Query: 593 AK 598 + Sbjct: 205 TR 206 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 81.0 bits (191), Expect = 2e-14 Identities = 47/134 (35%), Positives = 72/134 (53%), Gaps = 4/134 (2%) Frame = +2 Query: 203 VDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 370 + D+ + + +KV+ + G D LVNNA + L FD N K Sbjct: 62 IQADVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPF 121 Query: 371 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 550 S+ A+ M+++K+ G I+NISS K ++YSA+K+ L A T+++A ELGP+GI Sbjct: 122 LYSRAAAKLMLKHKS-GRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAKELGPFGI 180 Query: 551 RVNAINPTVIMTEM 592 VNAI P I T++ Sbjct: 181 TVNAIAPGFIDTDL 194 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 552,716,147 Number of Sequences: 1657284 Number of extensions: 9706145 Number of successful extensions: 35994 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 33309 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 34523 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 48126133708 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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