BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fmgV10h04f (635 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9V3D6 Cluster: Probable cleavage and polyadenylation s... 253 2e-66 UniRef50_Q9P2I0 Cluster: Cleavage and polyadenylation specificit... 246 3e-64 UniRef50_Q3UGU6 Cluster: Melanocyte cDNA, RIKEN full-length enri... 243 3e-63 UniRef50_A7RPX1 Cluster: Predicted protein; n=1; Nematostella ve... 233 3e-60 UniRef50_Q4S732 Cluster: Chromosome 14 SCAF14723, whole genome s... 221 9e-57 UniRef50_O17403 Cluster: Probable cleavage and polyadenylation s... 203 2e-51 UniRef50_Q8WPK6 Cluster: Similar to cleavage and polyadenylation... 191 1e-47 UniRef50_Q9LKF9 Cluster: Cleavage and polyadenylation specificit... 173 2e-42 UniRef50_Q55BS1 Cluster: Putative uncharacterized protein; n=1; ... 170 2e-41 UniRef50_Q01GI5 Cluster: Polyadenylation cleavage/specificity fa... 159 4e-38 UniRef50_A4RR19 Cluster: Predicted protein; n=1; Ostreococcus lu... 157 2e-37 UniRef50_A2EDT7 Cluster: Putative uncharacterized protein; n=1; ... 130 3e-29 UniRef50_UPI000049A022 Cluster: cleavage and polyadenylation spe... 85 1e-15 UniRef50_Q4PAM2 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13 UniRef50_O74740 Cluster: Cleavage factor two Cft2/polyadenylatio... 74 3e-12 UniRef50_Q2UQF0 Cluster: MRNA cleavage and polyadenylation facto... 71 2e-11 UniRef50_A2R7F5 Cluster: Contig An16c0120, complete genome. prec... 71 2e-11 UniRef50_Q5KIP3 Cluster: Cleavage and polyadenylation specificit... 71 2e-11 UniRef50_A7F0N0 Cluster: Putative uncharacterized protein; n=2; ... 71 3e-11 UniRef50_A6R733 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11 UniRef50_A5DXK9 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11 UniRef50_A3GHD1 Cluster: Predicted protein; n=3; Saccharomycetal... 66 5e-10 UniRef50_Q86A79 Cluster: Similar to Homo sapiens (Human). Cleava... 66 9e-10 UniRef50_UPI00015BD54C Cluster: UPI00015BD54C related cluster; n... 65 1e-09 UniRef50_Q8SUE4 Cluster: Putative uncharacterized protein ECU10_... 65 2e-09 UniRef50_Q6BSP2 Cluster: Similar to CA3384|IPF8362 Candida albic... 64 4e-09 UniRef50_Q0UZX3 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09 UniRef50_Q4QA79 Cluster: Cleavage and polyadenylation specificit... 62 1e-08 UniRef50_O13794 Cluster: Endoribonuclease ysh1; n=2; Ascomycota|... 62 1e-08 UniRef50_Q12102 Cluster: Protein CFT2; n=4; Saccharomyces cerevi... 60 4e-08 UniRef50_Q18IP5 Cluster: Predicted metal-dependent RNase, consis... 59 8e-08 UniRef50_Q750X1 Cluster: AGL182Cp; n=1; Eremothecium gossypii|Re... 58 2e-07 UniRef50_Q387M8 Cluster: Cleavage and polyadenylation specificit... 57 3e-07 UniRef50_Q5TA45 Cluster: Integrator complex subunit 11; n=29; Eu... 57 3e-07 UniRef50_A7APS1 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07 UniRef50_Q7S0J8 Cluster: Putative uncharacterized protein NCU068... 56 5e-07 UniRef50_Q74MJ3 Cluster: NEQ076; n=1; Nanoarchaeum equitans|Rep:... 56 7e-07 UniRef50_A3ERC5 Cluster: Putative RNA-processing exonuclease; n=... 56 9e-07 UniRef50_A4CGY6 Cluster: Putative uncharacterized protein; n=4; ... 55 1e-06 UniRef50_Q9U3K2 Cluster: Putative uncharacterized protein; n=2; ... 55 1e-06 UniRef50_Q8GUU3 Cluster: FEG protein; n=8; Magnoliophyta|Rep: FE... 55 2e-06 UniRef50_A6NEN7 Cluster: Uncharacterized protein CPSF3L; n=16; T... 54 2e-06 UniRef50_A4XI93 Cluster: Beta-lactamase domain protein; n=1; Cal... 54 3e-06 UniRef50_A4S2M5 Cluster: Predicted protein; n=4; Viridiplantae|R... 54 3e-06 UniRef50_Q5TA51 Cluster: Cleavage and polyadenylation specific f... 54 3e-06 UniRef50_Q4UDL0 Cluster: Putative uncharacterized protein; n=3; ... 54 4e-06 UniRef50_Q9YEQ9 Cluster: Putative exonuclease; n=1; Aeropyrum pe... 54 4e-06 UniRef50_Q5BEP0 Cluster: Endoribonuclease ysh1; n=15; Pezizomyco... 54 4e-06 UniRef50_Q6FW78 Cluster: Candida glabrata strain CBS138 chromoso... 53 5e-06 UniRef50_Q4Q2K1 Cluster: Cleavage and polyadenylation specificit... 53 7e-06 UniRef50_A2FCF8 Cluster: RNA-metabolising metallo-beta-lactamase... 53 7e-06 UniRef50_A0BGT5 Cluster: Chromosome undetermined scaffold_106, w... 53 7e-06 UniRef50_A1RWY8 Cluster: Beta-lactamase domain protein; n=1; The... 52 1e-05 UniRef50_A5ZRP6 Cluster: Putative uncharacterized protein; n=4; ... 52 2e-05 UniRef50_A3HWA3 Cluster: Metallo-beta-lactamase family protein; ... 51 3e-05 UniRef50_A2D958 Cluster: RNA-metabolising metallo-beta-lactamase... 51 3e-05 UniRef50_Q6CNJ8 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 51 3e-05 UniRef50_Q2LYC2 Cluster: Metallo-beta-lactamase protein; n=6; De... 50 4e-05 UniRef50_A5N1D0 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05 UniRef50_Q06224 Cluster: Endoribonuclease YSH1; n=10; Fungi/Meta... 50 4e-05 UniRef50_Q95PY8 Cluster: Putative uncharacterized protein; n=2; ... 50 5e-05 UniRef50_A7TEK7 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05 UniRef50_Q58633 Cluster: Uncharacterized protein MJ1236; n=16; E... 50 6e-05 UniRef50_Q24CH6 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05 UniRef50_A7DQ83 Cluster: Beta-lactamase domain protein; n=1; Can... 49 8e-05 UniRef50_Q5CRW9 Cluster: CPSF metallobeta-lactamase; n=2; Crypto... 49 1e-04 UniRef50_A1RTJ6 Cluster: Beta-lactamase domain protein; n=1; Pyr... 48 1e-04 UniRef50_Q5KCZ0 Cluster: Endoribonuclease YSH1; n=2; cellular or... 48 1e-04 UniRef50_UPI00015BA9DD Cluster: beta-lactamase domain protein; n... 48 2e-04 UniRef50_Q0LL72 Cluster: Beta-lactamase-like; n=3; Herpetosiphon... 48 2e-04 UniRef50_A6C193 Cluster: Exonuclease of the beta-lactamase fold ... 48 2e-04 UniRef50_Q9UKF6 Cluster: Cleavage and polyadenylation specificit... 48 2e-04 UniRef50_Q11PK2 Cluster: Metallo-beta-lactamase superfamily prot... 47 3e-04 UniRef50_Q5TA44 Cluster: Cleavage and polyadenylation specific f... 47 3e-04 UniRef50_Q8ZYD9 Cluster: MRNA 3'-end processing factor, conjectu... 47 3e-04 UniRef50_Q4PEJ3 Cluster: Endoribonuclease YSH1; n=6; Fungi/Metaz... 47 3e-04 UniRef50_Q6CAZ0 Cluster: Yarrowia lipolytica chromosome C of str... 47 4e-04 UniRef50_Q7RRQ3 Cluster: Cleavage and polyadenylation specificit... 46 6e-04 UniRef50_A6QXP5 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04 UniRef50_Q8KET4 Cluster: Metallo-beta-lactamase superfamily prot... 46 8e-04 UniRef50_Q73MR4 Cluster: Metallo-beta-lactamase family protein; ... 46 8e-04 UniRef50_Q4N0H3 Cluster: Putative uncharacterized protein; n=2; ... 46 8e-04 UniRef50_Q236M0 Cluster: RNA-metabolising metallo-beta-lactamase... 46 8e-04 UniRef50_Q8RBU2 Cluster: Predicted exonuclease of the beta-lacta... 46 0.001 UniRef50_Q23NE4 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_A0RXV0 Cluster: Cleavage and polyadenylation specificit... 46 0.001 UniRef50_Q1GJ92 Cluster: Beta-lactamase-like protein; n=4; Rhodo... 45 0.002 UniRef50_Q8SRZ4 Cluster: CLEAVAGE AND POLYADENYLATION SPECIFICIT... 44 0.002 UniRef50_Q6BMW3 Cluster: Endoribonuclease YSH1; n=2; Saccharomyc... 44 0.002 UniRef50_A5KD85 Cluster: Cleavage and polyadenylation specifity ... 44 0.003 UniRef50_Q3ZY44 Cluster: Metallo-beta-lactamase family protein; ... 44 0.004 UniRef50_Q2YZG4 Cluster: Predicted exonuclease of the beta-lacta... 44 0.004 UniRef50_Q7UMQ3 Cluster: Cleavage and polyadenylation specifity ... 43 0.005 UniRef50_Q15V20 Cluster: RNA-metabolising metallo-beta-lactamase... 43 0.005 UniRef50_Q8TW11 Cluster: Predicted metal-dependent RNase, consis... 43 0.005 UniRef50_A5KKJ4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007 UniRef50_A3I563 Cluster: Zn-dependent hydrolase, beta-lactamase ... 43 0.007 UniRef50_Q9UXE8 Cluster: MRNA 3'-end polyadenylation factor; n=6... 43 0.007 UniRef50_Q5CPX2 Cluster: Cleavage and polyadenylation specifity ... 42 0.009 UniRef50_Q97AZ6 Cluster: Cleavage and polyadenylation specificit... 42 0.009 UniRef50_Q9RZ85 Cluster: Cleavage and polyadenylation specificit... 42 0.012 UniRef50_Q6MLH4 Cluster: Predicted exonuclease of the beta-lacta... 42 0.012 UniRef50_A7QCN8 Cluster: Chromosome chr12 scaffold_78, whole gen... 42 0.012 UniRef50_Q7QYP3 Cluster: GLP_393_23867_26140; n=1; Giardia lambl... 42 0.012 UniRef50_A7AWH8 Cluster: RNA-metabolising metallo-beta-lactamase... 42 0.012 UniRef50_Q60355 Cluster: Uncharacterized protein MJ0047; n=6; Me... 42 0.012 UniRef50_UPI00004992E1 Cluster: cleavage and polyadenylation spe... 42 0.016 UniRef50_Q3AAG6 Cluster: Metallo-beta-lactamase family protein; ... 42 0.016 UniRef50_A3WMD7 Cluster: Predicted exonuclease of the beta-lacta... 42 0.016 UniRef50_Q0HMU8 Cluster: RNA-metabolizing metallo-beta-lactamase... 41 0.022 UniRef50_Q0EST3 Cluster: Beta-lactamase-like; n=2; Thermoanaerob... 41 0.022 UniRef50_Q023M0 Cluster: Beta-lactamase domain protein; n=1; Sol... 41 0.022 UniRef50_A7HPZ1 Cluster: Beta-lactamase domain protein; n=2; Alp... 41 0.022 UniRef50_A6FNJ5 Cluster: Beta-lactamase-like protein; n=1; Roseo... 41 0.022 UniRef50_A0JWK6 Cluster: Beta-lactamase domain protein; n=2; Bac... 41 0.022 UniRef50_Q2RJ88 Cluster: RNA-metabolising metallo-beta-lactamase... 41 0.029 UniRef50_A5URN4 Cluster: Beta-lactamase domain protein; n=5; Chl... 41 0.029 UniRef50_Q4AMZ9 Cluster: Beta-lactamase-like:RNA-metabolising me... 40 0.038 UniRef50_A5N0B8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.038 UniRef50_Q11BH9 Cluster: Beta-lactamase-like; n=6; Proteobacteri... 40 0.050 UniRef50_Q011B3 Cluster: Putative metallo beta subunit lactamase... 40 0.050 UniRef50_Q5WCW7 Cluster: Beta-lactamase superfamily Zn-dependent... 40 0.066 UniRef50_Q3LWF4 Cluster: Ysh1 3' mRNA end processing factor; n=1... 40 0.066 UniRef50_Q92EY9 Cluster: Lin0319 protein; n=39; Bacilli|Rep: Lin... 39 0.088 UniRef50_Q2NK28 Cluster: Zn-dependent hydrolase; n=2; Candidatus... 39 0.088 UniRef50_O87142 Cluster: WbfZ protein; n=32; Vibrionaceae|Rep: W... 39 0.088 UniRef50_A7CRQ7 Cluster: Beta-lactamase domain protein; n=1; Opi... 39 0.088 UniRef50_A0UZ06 Cluster: Beta-lactamase-like; n=1; Clostridium c... 39 0.088 UniRef50_Q8IB25 Cluster: Putative uncharacterized protein MAL8P1... 39 0.088 UniRef50_A6E886 Cluster: Metallo-beta-lactamase superfamily prot... 39 0.12 UniRef50_Q5ZWR4 Cluster: Metallo-beta lactamase family; n=4; Leg... 38 0.15 UniRef50_Q50EJ8 Cluster: Metallo-beta-lactamase superfamily hydr... 38 0.15 UniRef50_A3D3L5 Cluster: Putative uncharacterized protein; n=1; ... 38 0.15 UniRef50_Q6MTU5 Cluster: CONSERVED HYPOTEHTICAL PROTEIN; n=3; Mo... 38 0.20 UniRef50_Q6ME06 Cluster: Putative uncharacterized protein; n=1; ... 38 0.27 UniRef50_A6TSN2 Cluster: Beta-lactamase domain protein; n=1; Alk... 38 0.27 UniRef50_O31760 Cluster: UPF0036 protein ymfA; n=77; Firmicutes|... 38 0.27 UniRef50_A0YHA6 Cluster: DNA internalization-related competence ... 37 0.35 UniRef50_Q8DE34 Cluster: Predicted exonuclease of the beta-lacta... 37 0.47 UniRef50_Q72GW5 Cluster: Cleavage and polyadenylation specificit... 37 0.47 UniRef50_A4VJP5 Cluster: Metallo-beta-lactamase superfamily prot... 37 0.47 UniRef50_Q226C1 Cluster: Putative FEG protein; n=2; Tetrahymena ... 37 0.47 UniRef50_A7DPN0 Cluster: Beta-lactamase domain protein; n=1; Can... 37 0.47 UniRef50_UPI000049831F Cluster: cleavage and polyadenylation spe... 36 0.62 UniRef50_Q9SRR3 Cluster: F21O3.24 protein; n=3; core eudicotyled... 36 0.62 UniRef50_Q9FMW0 Cluster: Genomic DNA, chromosome 5, P1 clone:MLE... 36 0.62 UniRef50_Q9HKD3 Cluster: Putative uncharacterized protein Ta0668... 36 0.62 UniRef50_Q6D8S0 Cluster: Anaerobic nitric oxide reductase flavor... 36 0.62 UniRef50_Q4SGI2 Cluster: Chromosome undetermined SCAF14594, whol... 36 0.82 UniRef50_Q89VA5 Cluster: Bll1142 protein; n=7; Bradyrhizobiaceae... 36 0.82 UniRef50_Q2G7Y1 Cluster: Beta-lactamase-like protein; n=1; Novos... 36 0.82 UniRef50_Q1NVJ9 Cluster: Beta-lactamase-like:RNA-metabolising me... 36 0.82 UniRef50_A6Q9T8 Cluster: RNA-metabolising metallo-beta-lactamase... 36 0.82 UniRef50_A4EC58 Cluster: Putative uncharacterized protein; n=1; ... 36 0.82 UniRef50_A1ZG78 Cluster: Exonuclease of the beta-lactamase fold ... 36 0.82 UniRef50_A7PHF3 Cluster: Chromosome chr17 scaffold_16, whole gen... 36 0.82 UniRef50_Q4TC63 Cluster: Chromosome undetermined SCAF7053, whole... 36 1.1 UniRef50_Q9AA00 Cluster: Metallo-beta-lactamase family protein; ... 36 1.1 UniRef50_Q5QU60 Cluster: Predicted exonuclease of the beta-lacta... 36 1.1 UniRef50_Q3ADT3 Cluster: Anaerobic nitric oxide reductase flavor... 36 1.1 UniRef50_Q1B028 Cluster: Beta-lactamase-like protein; n=1; Rubro... 36 1.1 UniRef50_Q194D1 Cluster: Beta-lactamase-like; n=3; Clostridia|Re... 36 1.1 UniRef50_Q12E81 Cluster: Beta-lactamase-like; n=14; Proteobacter... 35 1.4 UniRef50_A6Q3H4 Cluster: RNA-metabolising metallo-beta-lactamase... 35 1.4 UniRef50_A1S0I1 Cluster: Beta-lactamase domain protein; n=1; The... 35 1.4 UniRef50_A4STH4 Cluster: Anaerobic nitric oxide reductase flavor... 35 1.4 UniRef50_Q31DU4 Cluster: Phosphonate metabolism accessory protei... 35 1.9 UniRef50_Q1PVS7 Cluster: Putative uncharacterized protein; n=1; ... 35 1.9 UniRef50_Q4UBM2 Cluster: Cleavage and polyadenylation specificty... 35 1.9 UniRef50_Q8RAH0 Cluster: Predicted hydrolase of the metallo-beta... 34 2.5 UniRef50_Q41CQ7 Cluster: Beta-lactamase-like; n=1; Exiguobacteri... 34 2.5 UniRef50_Q97DE0 Cluster: Metallo-beta-lactamase superfamily hydr... 34 3.3 UniRef50_Q5NLC0 Cluster: Metallo-beta-lactamase hydrolase subuni... 34 3.3 UniRef50_Q83XN5 Cluster: Putative beta-lactamase; n=1; Streptomy... 34 3.3 UniRef50_Q3Y227 Cluster: Beta-lactamase-like; n=1; Enterococcus ... 34 3.3 UniRef50_Q024Z8 Cluster: Beta-lactamase domain protein precursor... 34 3.3 UniRef50_A6PE29 Cluster: Beta-lactamase domain protein; n=1; She... 34 3.3 UniRef50_Q7QUX2 Cluster: GLP_577_37199_34023; n=1; Giardia lambl... 34 3.3 UniRef50_Q6BHT7 Cluster: Similar to CA2422|IPF14997 Candida albi... 34 3.3 UniRef50_A2SUA2 Cluster: Beta-lactamase domain protein; n=1; Met... 34 3.3 UniRef50_P54122 Cluster: UPF0036 protein Cgl1970/cg2160; n=31; A... 34 3.3 UniRef50_Q9NV88 Cluster: Integrator complex subunit 9; n=41; Eum... 34 3.3 UniRef50_Q9K9I5 Cluster: BH2662 protein; n=43; Bacteria|Rep: BH2... 33 4.4 UniRef50_Q97D03 Cluster: Metallo-beta-lactamase superfamily hydr... 33 4.4 UniRef50_Q81QL9 Cluster: Hydrolase, putative; n=10; Firmicutes|R... 33 4.4 UniRef50_Q748A2 Cluster: Metallo-beta-lactamase family protein; ... 33 4.4 UniRef50_Q1DC87 Cluster: Metallo-beta-lactamase family protein; ... 33 4.4 UniRef50_A6G7H1 Cluster: Serine/threonine kinase family protein;... 33 4.4 UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2; Ros... 33 4.4 UniRef50_A3TIY7 Cluster: Putative uncharacterized protein; n=1; ... 33 4.4 UniRef50_A5BGD5 Cluster: Putative uncharacterized protein; n=1; ... 33 4.4 UniRef50_Q4YUZ6 Cluster: Putative uncharacterized protein; n=4; ... 33 4.4 UniRef50_Q59M67 Cluster: Potential response regulator protein; n... 33 4.4 UniRef50_UPI0000E0E9AB Cluster: DNA internalization-related comp... 33 5.8 UniRef50_Q6N2A1 Cluster: Beta-lactamase-like; n=12; Rhizobiales|... 33 5.8 UniRef50_A7H6H0 Cluster: Beta-lactamase domain protein; n=2; Ana... 33 5.8 UniRef50_A6LMC9 Cluster: Beta-lactamase domain protein; n=1; The... 33 5.8 UniRef50_A5K7P0 Cluster: RNA-metabolising metallo-beta-lactamase... 33 5.8 UniRef50_A5K5Q9 Cluster: Putative uncharacterized protein; n=1; ... 33 5.8 UniRef50_A0D1M0 Cluster: Chromosome undetermined scaffold_34, wh... 33 5.8 UniRef50_Q5V0H4 Cluster: MRNA 3'-end processing factor; n=4; Hal... 33 5.8 UniRef50_A0RY50 Cluster: Exonuclease of the beta-lactamase fold;... 33 5.8 UniRef50_Q57626 Cluster: Uncharacterized protein MJ0162; n=6; Me... 33 5.8 UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1; Oc... 33 7.6 UniRef50_Q8DAV3 Cluster: Rec2-related protein; n=2; Vibrio vulni... 33 7.6 UniRef50_Q182G4 Cluster: Metallo beta-lactamase superfamily lipo... 33 7.6 UniRef50_Q54SH0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.6 UniRef50_A2QCH2 Cluster: Putative uncharacterized protein; n=1; ... 33 7.6 UniRef50_O29680 Cluster: Putative uncharacterized protein; n=1; ... 33 7.6 >UniRef50_Q9V3D6 Cluster: Probable cleavage and polyadenylation specificity factor subunit 2; n=7; Coelomata|Rep: Probable cleavage and polyadenylation specificity factor subunit 2 - Drosophila melanogaster (Fruit fly) Length = 756 Score = 253 bits (620), Expect = 2e-66 Identities = 110/156 (70%), Positives = 134/156 (85%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 MTSIIKLH +SGA +E+PPCY+LQID+ + LLDCGWDEKFD FIKELKR V+++DAVL+ Sbjct: 1 MTSIIKLHTISGAMDESPPCYILQIDDVRILLDCGWDEKFDANFIKELKRQVHTLDAVLL 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH D HLGALPY VGKLGL+CPIYAT+PV+KMGQMFMYDLY +H N+ +FDLF+LDDVD Sbjct: 61 SHPDAYHLGALPYLVGKLGLNCPIYATIPVFKMGQMFMYDLYMSHFNMGDFDLFSLDDVD 120 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 AF++I QLKYNQ++ +K KG G+ ITPL AGH +G Sbjct: 121 TAFEKITQLKYNQTVSLKDKGYGISITPLNAGHMIG 156 >UniRef50_Q9P2I0 Cluster: Cleavage and polyadenylation specificity factor subunit 2; n=26; Coelomata|Rep: Cleavage and polyadenylation specificity factor subunit 2 - Homo sapiens (Human) Length = 782 Score = 246 bits (602), Expect = 3e-64 Identities = 111/156 (71%), Positives = 129/156 (82%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 MTSIIKL LSG EE+ CY+LQ+DEF+FLLDCGWDE F M I L++HV+ IDAVL+ Sbjct: 1 MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSMDIIDSLRKHVHQIDAVLL 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH DPLHLGALPYAVGKLGL+C IYAT+PVYKMGQMFMYDLYQ+ N +F LFTLDDVD Sbjct: 61 SHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVD 120 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 AFD+I QLK++Q + +KGKG GL ITPLPAGH +G Sbjct: 121 AAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIG 156 >UniRef50_Q3UGU6 Cluster: Melanocyte cDNA, RIKEN full-length enriched library, clone:G270022C12 product:cleavage and polyadenylation specific factor 2, full insert sequence; n=5; Eutheria|Rep: Melanocyte cDNA, RIKEN full-length enriched library, clone:G270022C12 product:cleavage and polyadenylation specific factor 2, full insert sequence - Mus musculus (Mouse) Length = 412 Score = 243 bits (594), Expect = 3e-63 Identities = 109/156 (69%), Positives = 129/156 (82%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 MTSIIKL LSG EE+ CY+LQ+DEF+FLLDCGWDE F + I L++HV+ IDAVL+ Sbjct: 1 MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSVDIIDSLRKHVHQIDAVLL 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH DPLHLGALP+AVGKLGL+C IYAT+PVYKMGQMFMYDLYQ+ N +F LFTLDDVD Sbjct: 61 SHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVD 120 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 AFD+I QLK++Q + +KGKG GL ITPLPAGH +G Sbjct: 121 AAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIG 156 >UniRef50_A7RPX1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 737 Score = 233 bits (570), Expect = 3e-60 Identities = 100/156 (64%), Positives = 124/156 (79%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 MTSIIKL+ LSGA +E P CY+LQ+DEF+FLLDCGW+E DM ++ +KRHV +DAVL+ Sbjct: 1 MTSIIKLNVLSGAHDEAPLCYLLQVDEFRFLLDCGWNETLDMEIMESIKRHVQQVDAVLV 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 S D H+G LPY VGK GL CPIY T+PVYKMGQMFMYD YQ H+N EFD+F+LDDVD Sbjct: 61 SFPDIYHMGGLPYLVGKCGLHCPIYTTIPVYKMGQMFMYDWYQCHQNSEEFDVFSLDDVD 120 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 FD+I+QLKY+Q++ +KGKG G+ ITP AGH +G Sbjct: 121 AVFDKIIQLKYSQTVSLKGKGHGITITPYAAGHMIG 156 >UniRef50_Q4S732 Cluster: Chromosome 14 SCAF14723, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 14 SCAF14723, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 765 Score = 221 bits (541), Expect = 9e-57 Identities = 109/180 (60%), Positives = 129/180 (71%), Gaps = 24/180 (13%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 MTSIIKL +SG EE+ CY+LQ+DEF+FLLDCGWDE F M I +KR+V+ +DAVL+ Sbjct: 1 MTSIIKLTAVSGVQEESALCYLLQVDEFRFLLDCGWDENFSMDIIDAMKRYVHQVDAVLL 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH DP+HLGALPYAVGKLGL+C IYAT+PVYKMGQMFMYDLYQ+ N +F LFTLDDVD Sbjct: 61 SHPDPIHLGALPYAVGKLGLNCTIYATIPVYKMGQMFMYDLYQSRNNSEDFTLFTLDDVD 120 Query: 528 MAFDRIVQLKYNQSIEMK------------------------GKGLGLRITPLPAGHSLG 635 AFD+I QLKY+Q + +K GKG GL ITPLPAGH +G Sbjct: 121 SAFDKIQQLKYSQIVSLKGKLASKRLFTWSKLPKYVMAFYATGKGHGLSITPLPAGHMIG 180 >UniRef50_O17403 Cluster: Probable cleavage and polyadenylation specificity factor subunit 2; n=2; Caenorhabditis|Rep: Probable cleavage and polyadenylation specificity factor subunit 2 - Caenorhabditis elegans Length = 843 Score = 203 bits (496), Expect = 2e-51 Identities = 92/156 (58%), Positives = 117/156 (75%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 MTSIIKL SGA +E P CY+LQ+D LLDCGWDE+F + + +ELK + I AVLI Sbjct: 1 MTSIIKLKVFSGAKDEGPLCYLLQVDGDYILLDCGWDERFGLQYFEELKPFIPKISAVLI 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH DPLHLG LPY V K GL+ P+YAT+PVYKMGQMF+YD+ +H +V EF+ +TLDDVD Sbjct: 61 SHPDPLHLGGLPYLVSKCGLTAPVYATVPVYKMGQMFIYDMVYSHLDVEEFEHYTLDDVD 120 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 AF+++ Q+KYNQ++ +KG G+ T LPAGH LG Sbjct: 121 TAFEKVEQVKYNQTVVLKGDS-GVHFTALPAGHMLG 155 >UniRef50_Q8WPK6 Cluster: Similar to cleavage and polyadenylation factor; n=1; Oikopleura dioica|Rep: Similar to cleavage and polyadenylation factor - Oikopleura dioica (Tunicate) Length = 765 Score = 191 bits (465), Expect = 1e-47 Identities = 87/156 (55%), Positives = 111/156 (71%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 MTSI+K LSG +E P C++LQID+FKFLLDCGW E+ I LKRH IDA+LI Sbjct: 1 MTSIVKFQSLSGFDDEAPHCHLLQIDDFKFLLDCGWAEQHHEKIIDGLKRHGRQIDAILI 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH D LH G LPY + KLG++CPIY T+P KMGQMF+YD + V +FD+FTLDDVD Sbjct: 61 SHPDLLHCGMLPY-LSKLGITCPIYMTMPACKMGQMFLYDFVLSRTAVEDFDMFTLDDVD 119 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 FDR QLK+NQ+ ++G+ G++I P+ AGH +G Sbjct: 120 AVFDRATQLKHNQTEAVRGQDYGIQIMPVQAGHMIG 155 >UniRef50_Q9LKF9 Cluster: Cleavage and polyadenylation specificity factor subunit 2; n=8; Magnoliophyta|Rep: Cleavage and polyadenylation specificity factor subunit 2 - Arabidopsis thaliana (Mouse-ear cress) Length = 739 Score = 173 bits (422), Expect = 2e-42 Identities = 77/156 (49%), Positives = 110/156 (70%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 M + +++ L G E P Y++ ID F FL+DCGW++ FD ++ L R ++IDAVL+ Sbjct: 1 MGTSVQVTPLCGVYNENPLSYLVSIDGFNFLIDCGWNDLFDTSLLEPLSRVASTIDAVLL 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH D LH+GALPYA+ +LGLS P+YAT PV+++G + MYD + + K VS+FDLFTLDD+D Sbjct: 61 SHPDTLHIGALPYAMKQLGLSAPVYATEPVHRLGLLTMYDQFLSRKQVSDFDLFTLDDID 120 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 AF +++L Y+Q+ + GKG G+ I P AGH LG Sbjct: 121 SAFQNVIRLTYSQNYHLSGKGEGIVIAPHVAGHMLG 156 >UniRef50_Q55BS1 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 784 Score = 170 bits (414), Expect = 2e-41 Identities = 79/158 (50%), Positives = 105/158 (66%), Gaps = 2/158 (1%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347 M SIIK LSGA +E+PPCY+L+ID+F LLDCG D ++ L++ IDAVL+ Sbjct: 1 MASIIKFTALSGAKDESPPCYLLEIDDFCILLDCGLSYNLDFSLLEPLEKVAKKIDAVLL 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SHSD H+G LPY VGK GL+ IY T PV KMG MF+YDLY+ + EF ++LD++D Sbjct: 61 SHSDTTHIGGLPYVVGKYGLTGTIYGTTPVLKMGTMFLYDLYENKMSQEEFQQYSLDNID 120 Query: 528 MAF--DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 F DR +L ++Q + GKG G+ ITP AGH++G Sbjct: 121 SCFGEDRFKELSFSQHYSLSGKGKGISITPYLAGHTIG 158 >UniRef50_Q01GI5 Cluster: Polyadenylation cleavage/specificity factor 100 kDa subunit; n=1; Ostreococcus tauri|Rep: Polyadenylation cleavage/specificity factor 100 kDa subunit - Ostreococcus tauri Length = 807 Score = 159 bits (387), Expect = 4e-38 Identities = 75/146 (51%), Positives = 98/146 (67%), Gaps = 1/146 (0%) Frame = +3 Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380 GAGE CY + ID LLDCGW + FD+ +K L+ +DAVLISH D HLGAL Sbjct: 40 GAGERAM-CYHVSIDGCNILLDCGWTDAFDVEMLKPLEAIAKDVDAVLISHPDTAHLGAL 98 Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF-DLFTLDDVDMAFDRIVQLK 557 PYA GKLG++C +YATLPV+KMGQM+MYD + ++ +F + F+LDDVD AF V +K Sbjct: 99 PYAFGKLGMNCKVYATLPVHKMGQMYMYDHFLTRQDQEDFQETFSLDDVDKAFAAFVPVK 158 Query: 558 YNQSIEMKGKGLGLRITPLPAGHSLG 635 Y Q ++GKG G+ + AGH+LG Sbjct: 159 YQQLSMLRGKGEGISVMAYAAGHTLG 184 >UniRef50_A4RR19 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 715 Score = 157 bits (381), Expect = 2e-37 Identities = 72/138 (52%), Positives = 96/138 (69%), Gaps = 1/138 (0%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404 CY + ID LLDCGW++KFD+ +K L +DAVLISH D HLGALPYA GKLG Sbjct: 2 CYHVSIDGCNILLDCGWNDKFDVDMLKPLAAIAPKVDAVLISHPDTAHLGALPYAFGKLG 61 Query: 405 LSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF-DLFTLDDVDMAFDRIVQLKYNQSIEMK 581 ++C +YATLPV+KMGQM+MYD + ++ +F ++F+LDDVD AF V +KY Q ++ Sbjct: 62 MNCKVYATLPVHKMGQMYMYDHFLTRQDQGDFQEVFSLDDVDTAFAAFVPVKYMQLSMLR 121 Query: 582 GKGLGLRITPLPAGHSLG 635 GKG G+ + AGH+LG Sbjct: 122 GKGDGISVMAYAAGHTLG 139 >UniRef50_A2EDT7 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 700 Score = 130 bits (314), Expect = 3e-29 Identities = 66/155 (42%), Positives = 95/155 (61%) Frame = +3 Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLIS 350 T+ I LSGA TP Y+L +DEF FLLDCGW E F + I+ + ++AVL+S Sbjct: 5 TTSISFQPLSGAQSTTPFAYLLHVDEFTFLLDCGWTEDFRLEDIQTQIEICSHVNAVLLS 64 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDM 530 H+ H+GALPY GLS PI+AT+P+ +G + +YD Y ++ EF F +D+D Sbjct: 65 HASIEHIGALPYLCSH-GLSAPIFATMPIPALGSLLIYDSYLNIRDEEEFKEFNANDIDQ 123 Query: 531 AFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 AF +I ++ Y QS ++ GK + ITP AG++LG Sbjct: 124 AFQKINRMTYQQSEQLDGK--NITITPYNAGNTLG 156 >UniRef50_UPI000049A022 Cluster: cleavage and polyadenylation specificity factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cleavage and polyadenylation specificity factor - Entamoeba histolytica HM-1:IMSS Length = 693 Score = 85.4 bits (202), Expect = 1e-15 Identities = 53/152 (34%), Positives = 83/152 (54%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359 I+ L G+ +P +L+I+ K LLDCG D F I++ ++ ID VLISHSD Sbjct: 3 IRTRSLFDGGKTSPISALLEINSTKILLDCGVDCNFTREIIEKYDS-ISDIDIVLISHSD 61 Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFD 539 H+GALPY K +C IY T PV KMG + M + + + + + + L DV+ + Sbjct: 62 LRHMGALPYIANK-NPNCSIYTTDPVGKMGYLCMKEAIKTQQLIG-YPCYRLKDVEQTYK 119 Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 RI L+Y ++ G+ + ++ P+G +LG Sbjct: 120 RIFLLEY-YKLQKCGE---VEVSAHPSGRTLG 147 >UniRef50_Q4PAM2 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 979 Score = 77.0 bits (181), Expect = 4e-13 Identities = 44/120 (36%), Positives = 66/120 (55%), Gaps = 11/120 (9%) Frame = +3 Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKN 488 L++ ++ID VL+SHS HLG YA LGL C +YAT+PV MG++ + + Q ++ Sbjct: 120 LRQLASTIDLVLLSHSSLDHLGLYAYAHANLGLRCQVYATMPVQSMGKLTVLEAIQTWRS 179 Query: 489 VSEFD-----------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + + L T D V+ AF+ I ++Y Q ++GK L +T AGHSLG Sbjct: 180 EVDIEKECTSASTRRCLATPDQVEDAFEEIKTVRYMQPTHLEGKCASLTLTAYNAGHSLG 239 >UniRef50_O74740 Cluster: Cleavage factor two Cft2/polyadenylation factor CPSF-73; n=1; Schizosaccharomyces pombe|Rep: Cleavage factor two Cft2/polyadenylation factor CPSF-73 - Schizosaccharomyces pombe (Fission yeast) Length = 797 Score = 73.7 bits (173), Expect = 3e-12 Identities = 44/102 (43%), Positives = 59/102 (57%), Gaps = 1/102 (0%) Frame = +3 Query: 333 DAVLISHSDPLHLGALPYAVGKLGL-SCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509 D +L+SHSD H+G L YA K + IYATLP MG+M M D +++ +S+ Sbjct: 45 DLILLSHSDLAHIGGLVYAYYKYDWKNAYIYATLPTINMGRMTMLDAIKSNY-ISDM--- 100 Query: 510 TLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + DVD FD I+ L+Y Q + GK GL IT AGH+LG Sbjct: 101 SKADVDAVFDSIIPLRYQQPTLLLGKCSGLTITAYNAGHTLG 142 >UniRef50_Q2UQF0 Cluster: MRNA cleavage and polyadenylation factor II complex; n=7; Eurotiomycetidae|Rep: MRNA cleavage and polyadenylation factor II complex - Aspergillus oryzae Length = 1014 Score = 71.3 bits (167), Expect = 2e-11 Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 3/93 (3%) Frame = +3 Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407 +L++D K L+D GWD+ FD + ++EL++HV ++ +L++H+ P H+GA + L Sbjct: 21 ILELDGGIKILVDVGWDDTFDPLDLQELEKHVPTLSLILLTHATPAHIGAFAHCCKTFPL 80 Query: 408 --SCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500 P+YAT PV +G+ + DLY + + F Sbjct: 81 FTQIPVYATSPVIALGRTLLQDLYASSPLAATF 113 >UniRef50_A2R7F5 Cluster: Contig An16c0120, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An16c0120, complete genome. precursor - Aspergillus niger Length = 865 Score = 71.3 bits (167), Expect = 2e-11 Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 3/93 (3%) Frame = +3 Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407 +L++D K L+D GWD+ FD + ++EL++HV ++ +L++H+ P H+GA + L Sbjct: 21 ILELDGGIKILVDVGWDDTFDPLDLQELEKHVPTLSLILLTHATPAHIGAFAHCCKTFPL 80 Query: 408 --SCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500 P+YAT PV +G+ + DLY + + F Sbjct: 81 FTQIPVYATSPVIALGRTLLQDLYASSPLAATF 113 >UniRef50_Q5KIP3 Cluster: Cleavage and polyadenylation specificity factor subunit, putative; n=1; Filobasidiella neoformans|Rep: Cleavage and polyadenylation specificity factor subunit, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 899 Score = 70.9 bits (166), Expect = 2e-11 Identities = 50/181 (27%), Positives = 90/181 (49%), Gaps = 28/181 (15%) Frame = +3 Query: 177 IIKLHCLSGAGEETPP----CYVLQIDEFKFLLDCGW------DEKFDMVFIKELKRHVN 326 +I L LS + ET P CY+L++D+ + LLD G ++ + + ++ Sbjct: 1 MITLTPLSASAAETSPSEPICYLLELDDARILLDMGQRDYRASSQQCSWDYEEAVRDLAP 60 Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD- 503 ++ VL+SHS +L PYA + GL+CP+YAT P +MG++ ++ ++ D Sbjct: 61 TLSLVLLSHSSSNYLSLYPYARARWGLTCPVYATQPTVEMGRVVCLAEAESWRSECPVDS 120 Query: 504 -----------------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSL 632 + T++++ AFD I ++Y+Q + + G L +TP +GH+L Sbjct: 121 EKVAADDGSKKPLRGPFVPTVEEIHEAFDWIKAVRYSQPLHLGGDFSHLLLTPFASGHTL 180 Query: 633 G 635 G Sbjct: 181 G 181 >UniRef50_A7F0N0 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 936 Score = 70.5 bits (165), Expect = 3e-11 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 13/160 (8%) Frame = +3 Query: 195 LSGAGEETPPCY-VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLH 368 L GA E+ +L++D K L+D GWDE FD+ ++EL++ + ++ +L++H+ H Sbjct: 7 LQGAQSESSASQSLLELDGGVKVLIDVGWDETFDVEKLRELEKQIPTLSLILLTHATVPH 66 Query: 369 LGALPYAVGKLGL--SCPIYATLPVYKMGQMFMYDLYQAH-------KNVSEFDLF--TL 515 + A + L P+YAT PV +G+ + DLY + S F L T Sbjct: 67 IAAYAHCCKHFPLFTRIPVYATHPVIALGRTLLQDLYSSTPLASTVIPTTSSFLLQPPTK 126 Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 ++++ F + LKY+Q + G+ IT AGHSLG Sbjct: 127 EEINYYFSLVRPLKYSQPHQPLN---GVTITAYNAGHSLG 163 >UniRef50_A6R733 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 977 Score = 70.1 bits (164), Expect = 4e-11 Identities = 33/86 (38%), Positives = 52/86 (60%), Gaps = 3/86 (3%) Frame = +3 Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407 +L++D K L+D GWDE FD+ + EL+R + ++ VL++H+ P H+GA + L Sbjct: 21 ILELDGGVKILVDVGWDESFDVSALAELERQIPTLSLVLLTHATPSHIGAFAHCCKTFPL 80 Query: 408 --SCPIYATLPVYKMGQMFMYDLYQA 479 PIYAT PV +G+ + DLY + Sbjct: 81 FNQIPIYATSPVIALGRTLLQDLYSS 106 >UniRef50_A5DXK9 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 1067 Score = 70.1 bits (164), Expect = 4e-11 Identities = 45/137 (32%), Positives = 77/137 (56%), Gaps = 6/137 (4%) Frame = +3 Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGA---LPYAVGKLGLSC 413 +E + L D W D + +K +++++ SIDA++ISHS + L K+ L+ Sbjct: 25 NEHRILADPSWSGS-DALVVKFMEQYLPSIDAIIISHSTTEFISGYILLCIYFPKIMLTI 83 Query: 414 PIYATLPVYKMGQMFMYDLYQAHKNVSEF--DLFTLDDVDMAFDRIVQLKYNQSIEM-KG 584 P+Y+TLPV ++G++ + Y++ + L LD++D FD+ +KY Q+I + G Sbjct: 84 PVYSTLPVNQLGRISTVEYYRSQGVLGPVLSSLIELDEIDNWFDKFKTVKYLQNITLCDG 143 Query: 585 KGLGLRITPLPAGHSLG 635 K L +TP +GHSLG Sbjct: 144 K---LTMTPYNSGHSLG 157 >UniRef50_A3GHD1 Cluster: Predicted protein; n=3; Saccharomycetales|Rep: Predicted protein - Pichia stipitis (Yeast) Length = 934 Score = 66.5 bits (155), Expect = 5e-10 Identities = 43/136 (31%), Positives = 75/136 (55%), Gaps = 5/136 (3%) Frame = +3 Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK---LGLSC 413 +EF+ L D W+ K D+ + +++H+ + + +L+SHS P + K L + Sbjct: 25 NEFRVLADPSWNGK-DVNSVMFMEQHLRNTNIILLSHSTPEFISGYVLMCLKFPNLMANI 83 Query: 414 PIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFDRIVQLKYNQSIEMKGK 587 +Y+TLPV ++G++ + Y+A+ + + L LD+VD FD+I LKY Q + + Sbjct: 84 QVYSTLPVNQLGRLSTVEFYRANGMLGPLNTALLELDEVDEWFDKISLLKYLQILNVFDN 143 Query: 588 GLGLRITPLPAGHSLG 635 + ITP AGH+LG Sbjct: 144 --KVVITPYNAGHTLG 157 >UniRef50_Q86A79 Cluster: Similar to Homo sapiens (Human). Cleavage and polyadenylation specificity factor, 73 kDa subunit; n=2; Dictyostelium discoideum|Rep: Similar to Homo sapiens (Human). Cleavage and polyadenylation specificity factor, 73 kDa subunit - Dictyostelium discoideum (Slime mold) Length = 774 Score = 65.7 bits (153), Expect = 9e-10 Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 7/152 (4%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDPL 365 G+G E C +L+ K + DCG + + F ++ + ID +L+SH Sbjct: 42 GSGSEVGRSCVLLKYKGKKVMFDCGVHPAYSGLVSLPFFDSIESDIPDIDLLLVSHFHLD 101 Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFD 539 H A+PY VGK ++ T P + M + D Y N++ D LF D+D + + Sbjct: 102 HAAAVPYFVGKTKFKGRVFMTHPTKAIYGMLLSD-YVKVSNITRDDDMLFDKSDLDRSLE 160 Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +I +++Y Q +E G+++T AGH LG Sbjct: 161 KIEKVRYRQKVEHN----GIKVTCFNAGHVLG 188 >UniRef50_UPI00015BD54C Cluster: UPI00015BD54C related cluster; n=1; unknown|Rep: UPI00015BD54C UniRef100 entry - unknown Length = 451 Score = 65.3 bits (152), Expect = 1e-09 Identities = 47/165 (28%), Positives = 76/165 (46%), Gaps = 13/165 (7%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359 +K+ A T ++L +D+ K L+DCG + D +EL +DAVL++H+ Sbjct: 1 MKVISYGAAKTVTGSAHMLILDDEKILIDCGLFQGVDEEKSEELGFDPKEVDAVLLTHAH 60 Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL-------YQAHK------NVSEF 500 H G +P + K G IY T P Y++ ++ + D Y++H + E Sbjct: 61 IDHCGRIPMLI-KNGFKGKIYCTRPTYELSRLMLLDTAKVMLENYKSHMKRFQRGTIKEI 119 Query: 501 DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L L D D F+ + + S + LG ++TP AGH LG Sbjct: 120 PLEPLYDEDDVFEALEHFEPTFSYDKTYDILGAKVTPKDAGHILG 164 >UniRef50_Q8SUE4 Cluster: Putative uncharacterized protein ECU10_0900; n=1; Encephalitozoon cuniculi|Rep: Putative uncharacterized protein ECU10_0900 - Encephalitozoon cuniculi Length = 730 Score = 64.9 bits (151), Expect = 2e-09 Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 2/154 (1%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD-MVFIKELKR-HVNSIDAVLISH 353 IK+ L E C +++ +LDCG + M + L ++ IDAV I+H Sbjct: 94 IKIMPLGAGNEVGRSCVIVECGGRTIMLDCGVHPAYTGMASLPFLDLVDLSKIDAVFITH 153 Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMA 533 H ALP+ K +Y T P + + + D + S+ D +T D+ Sbjct: 154 FHLDHAAALPFLTEKTSFRGKVYMTHPTKAILKWLLNDYIRIINASSDTDFYTETDLVKC 213 Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +DRI+ + Y+Q + +K G+++ L AGH LG Sbjct: 214 YDRIIPIDYHQEVNVK----GIKVKALNAGHVLG 243 >UniRef50_Q6BSP2 Cluster: Similar to CA3384|IPF8362 Candida albicans IPF8362; n=1; Debaryomyces hansenii|Rep: Similar to CA3384|IPF8362 Candida albicans IPF8362 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 959 Score = 63.7 bits (148), Expect = 4e-09 Identities = 41/136 (30%), Positives = 75/136 (55%), Gaps = 5/136 (3%) Frame = +3 Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK---LGLSC 413 ++ K L D W+ + I +++++ +D +L+SHS P + K L + Sbjct: 25 NDIKILADPSWNGN-NHNDILYMEQYLKEVDIILLSHSTPEFISGFVLLCIKFPNLMSNI 83 Query: 414 PIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFDRIVQLKYNQSIEMKGK 587 PIY+TLPV ++G++ + Y+A+ + + + +D+VD FD+I+ LK+ Q++ + Sbjct: 84 PIYSTLPVNQLGRVSTVEYYRANGVLGPLNNSILEVDEVDEWFDKIIPLKFFQTLSVFDN 143 Query: 588 GLGLRITPLPAGHSLG 635 L ITP AGH+LG Sbjct: 144 --RLVITPYNAGHTLG 157 >UniRef50_Q0UZX3 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 934 Score = 62.9 bits (146), Expect = 6e-09 Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 11/85 (12%) Frame = +3 Query: 252 KFLLDCGWDEKFDMVFIKELK---------RHVNSIDAVLISHSDPLHLGALPYAVGKLG 404 K L+D GWDE FD+ +KE++ RHV+++ VL++H+ HLGA + Sbjct: 28 KILIDVGWDESFDVAKLKEIERIQADVLFCRHVSTLSFVLLTHATTAHLGAYVHCCKNFP 87 Query: 405 L--SCPIYATLPVYKMGQMFMYDLY 473 L P+YAT+PV +G+ + DLY Sbjct: 88 LFSRVPVYATVPVISLGRTLLQDLY 112 >UniRef50_Q4QA79 Cluster: Cleavage and polyadenylation specificity factor, putative; n=3; Leishmania|Rep: Cleavage and polyadenylation specificity factor, putative - Leishmania major Length = 828 Score = 61.7 bits (143), Expect = 1e-08 Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 8/147 (5%) Frame = +3 Query: 219 PPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398 P Y++ ID + L DCGW+++FD F+ +LK H+ ++ AV++S GALP+ + Sbjct: 23 PYAYLVDIDGVRILFDCGWNDEFDTSFLNKLKPHLPTVHAVVLSSPHITACGALPFVLSH 82 Query: 399 LGLSCPIYATLPVYKMG-----QMFMYDLYQAHK-NVSEFDLFTL--DDVDMAFDRIVQL 554 + + A K+G F+Y +H +++ + FT+ D + +F R ++ Sbjct: 83 ISPGTFVAAAGGTSKIGVHSVLHSFLYQYPNSHTFTLADGEAFTMTVDSIYHSF-RSLRE 141 Query: 555 KYNQSIEMKGKGLGLRITPLPAGHSLG 635 Y + +K + + + AG LG Sbjct: 142 PYGGKVTVKNDDVEVNCFAVFAGRMLG 168 >UniRef50_O13794 Cluster: Endoribonuclease ysh1; n=2; Ascomycota|Rep: Endoribonuclease ysh1 - Schizosaccharomyces pombe (Fission yeast) Length = 775 Score = 61.7 bits (143), Expect = 1e-08 Identities = 44/150 (29%), Positives = 72/150 (48%), Gaps = 5/150 (3%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDPL 365 GAG E C+V+Q +LD G + + F E ++++D +LISH Sbjct: 43 GAGNEVGRSCHVIQYKGKTVMLDAGVHPAYTGLSALPFFDEFD--LSTVDVLLISHFHLD 100 Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRI 545 H+ +LPY + K ++ T P + + + D + E L+ D+ AFDRI Sbjct: 101 HVASLPYVMQKTNFRGRVFMTHPTKAVCKWLLSDYVKVSNVGMEDQLYDEKDLLAAFDRI 160 Query: 546 VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + Y+ +IE++ G++ TP AGH LG Sbjct: 161 EAVDYHSTIEVE----GIKFTPYHAGHVLG 186 >UniRef50_Q12102 Cluster: Protein CFT2; n=4; Saccharomyces cerevisiae|Rep: Protein CFT2 - Saccharomyces cerevisiae (Baker's yeast) Length = 859 Score = 60.1 bits (139), Expect = 4e-08 Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 9/153 (5%) Frame = +3 Query: 192 CLSGAGEETPPCYVLQIDEFKFLLDCGWDEK---FDMVFIKELKRHVNSIDAVLISHSDP 362 C G+G T V++ D L+D GW+ ++ IK ++ + ID +++S Sbjct: 8 CDDGSG--TTVGSVVRFDNVTLLIDPGWNPSKVSYEQC-IKYWEKVIPEIDVIILSQPTI 64 Query: 363 LHLGA---LPYAVGKLGLS-CPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLD--DV 524 LGA L Y +S +YATLPV +G++ D Y + + +D LD D+ Sbjct: 65 ECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTIDSYASAGVIGPYDTNKLDLEDI 124 Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAG 623 +++FD IV LKY+Q ++++ + GL + AG Sbjct: 125 EISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAG 157 >UniRef50_Q18IP5 Cluster: Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain; n=1; Haloquadratum walsbyi DSM 16790|Rep: Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain - Haloquadratum walsbyi (strain DSM 16790) Length = 538 Score = 59.3 bits (137), Expect = 8e-08 Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 7/130 (5%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGA 377 G G+E CY LQ ++ + +DCG + + IDAV I+H+ H+G Sbjct: 10 GGGDEVGRSCYHLQAGDYDYFIDCGLKQSETPEYPLFEDVSQGQIDAVFITHAHIDHIGG 69 Query: 378 LPYAV--GKLGLSCPIYATLPVYKMGQMFMYDLYQAHK----NVSEFDLFTLDDVDMAFD 539 LP A G L I+ T P + + ++D Q HK +++ FT D++ Sbjct: 70 LPVAEHHGLLDDDASIFMTRPTNALASILLHDSLQIHKQETAELNQPQQFTATDIEQVLS 129 Query: 540 RIVQLKYNQS 569 RI+ + YN++ Sbjct: 130 RIMTIGYNRN 139 >UniRef50_Q750X1 Cluster: AGL182Cp; n=1; Eremothecium gossypii|Rep: AGL182Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 803 Score = 57.6 bits (133), Expect = 2e-07 Identities = 41/157 (26%), Positives = 72/157 (45%), Gaps = 8/157 (5%) Frame = +3 Query: 189 HCLSGAGEETPPCYVLQIDEFKFLLDCGWDE--KFDMVFIKELKRHVNSIDAVLISHSDP 362 +C +G T +L D L+D GW +D + K + +D +L+S Sbjct: 7 YCKDESGSTTGT--ILSFDNCTLLIDPGWSGGCSYDEC-MAYWKEWIPQVDIILLSQPIQ 63 Query: 363 LHLGALPYA----VGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLD--DV 524 +GA + +Y+TLPV +G++ DLY + + FD +D D+ Sbjct: 64 ECIGAYAALFFDYISHFNSRIQVYSTLPVANLGRVATVDLYASLGIIGPFDTNRIDIEDI 123 Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 D AFD + +KY+Q +++K + GL + +G + G Sbjct: 124 DTAFDHLNTVKYSQLVDLKSRFDGLSLVAYSSGFAPG 160 >UniRef50_Q387M8 Cluster: Cleavage and polyadenylation specificity factor, putative; n=2; Trypanosoma|Rep: Cleavage and polyadenylation specificity factor, putative - Trypanosoma brucei Length = 818 Score = 57.2 bits (132), Expect = 3e-07 Identities = 40/149 (26%), Positives = 74/149 (49%), Gaps = 10/149 (6%) Frame = +3 Query: 219 PPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398 P Y+L+ID + L+DCGW++ F+ ++ L ++ + AVL S + GALP+ + Sbjct: 28 PMAYLLEIDGVRILMDCGWNDGFETSYLDALLPYLGDLHAVLFSTPELSSCGALPFVMEH 87 Query: 399 LGLSCPIYATLPVYKMG-----QMFMY-----DLYQAHKNVSEFDLFTLDDVDMAFDRIV 548 + + A KMG F+Y + ++ V EF++ T+D + AF R V Sbjct: 88 ITAETHVAAAGATAKMGLHGLLHPFLYLFPNTNTWKLQSGV-EFEM-TVDKIYSAF-RSV 144 Query: 549 QLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + Y + ++ + + + P+ +G LG Sbjct: 145 REPYGGKVTIRHRDVEVECFPVFSGRMLG 173 >UniRef50_Q5TA45 Cluster: Integrator complex subunit 11; n=29; Eukaryota|Rep: Integrator complex subunit 11 - Homo sapiens (Human) Length = 600 Score = 57.2 bits (132), Expect = 3e-07 Identities = 45/154 (29%), Positives = 72/154 (46%), Gaps = 9/154 (5%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356 GAG++ C ++ I +LDCG D +F D +I + R + +D V+ISH Sbjct: 10 GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 69 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ-AHKNVSEFDLFTLDDVDMA 533 H GALPY +G PIY T P + + + D + A E + FT + Sbjct: 70 HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDC 129 Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 ++V + +Q++++ + L I AGH LG Sbjct: 130 MKKVVAVHLHQTVQVDDE---LEIKAYYAGHVLG 160 >UniRef50_A7APS1 Cluster: Putative uncharacterized protein; n=1; Babesia bovis|Rep: Putative uncharacterized protein - Babesia bovis Length = 943 Score = 56.4 bits (130), Expect = 5e-07 Identities = 41/136 (30%), Positives = 66/136 (48%), Gaps = 10/136 (7%) Frame = +3 Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP--YA---VGKLGLSCP-I 419 L++CGW F+ I LK+ + +D ++++ D H+GALP Y+ V + GL P I Sbjct: 98 LVNCGWSLDFEPESIDLLKQCCSDVDVIILTDGDFGHVGALPVIYSWLHVVRDGLGLPSI 157 Query: 420 YATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGL 599 T YK + + D+ +F+ + D+D+ + V L+Y +S G G Sbjct: 158 LCTEGCYKFARACLVDVLDNATLSYKFEGYNFSDLDLFYSGCVTLRYRESFPFVKSGEGW 217 Query: 600 RI----TPLPAGHSLG 635 RI PL G S+G Sbjct: 218 RIHISLLPLNNGVSIG 233 >UniRef50_Q7S0J8 Cluster: Putative uncharacterized protein NCU06869.1; n=4; Sordariomycetes|Rep: Putative uncharacterized protein NCU06869.1 - Neurospora crassa Length = 1002 Score = 56.4 bits (130), Expect = 5e-07 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Frame = +3 Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG- 404 +L++D K L+D GWDE FD+ +KEL + ++ +L++H+ HL A + Sbjct: 20 LLELDGGVKILIDVGWDETFDVEKLKELGKQAPTLSLILLTHATVPHLAAYAHCCKHFPP 79 Query: 405 -LSCPIYATLPVYKMGQMFMYDLY 473 P+YAT PV +G+ DLY Sbjct: 80 FQRIPVYATRPVIDLGRTLTQDLY 103 >UniRef50_Q74MJ3 Cluster: NEQ076; n=1; Nanoarchaeum equitans|Rep: NEQ076 - Nanoarchaeum equitans Length = 635 Score = 56.0 bits (129), Expect = 7e-07 Identities = 44/158 (27%), Positives = 76/158 (48%), Gaps = 6/158 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKF-----DMVFIKELKRH-VNSIDAV 341 +++ L GA + +LQ E + LLD G D + I EL V +DAV Sbjct: 189 VRVSFLGGASQVGRSALLLQTKESRILLDFGVDLSLPPNNKNAYPIVELPEFDVKELDAV 248 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDD 521 +I+H+ H+G +P+ + K+G P+Y T P + + + D Y N + LF+ DD Sbjct: 249 VITHAHLDHVGFVPF-LYKMGYKGPVYLTPPTLDIATLSLLD-YLRIANENNVKLFSGDD 306 Query: 522 VDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + + ++Y Q+ ++ +++T AGH LG Sbjct: 307 IRNFVKHSITIEYGQTTDIAS---DVKLTFYNAGHILG 341 >UniRef50_A3ERC5 Cluster: Putative RNA-processing exonuclease; n=1; Leptospirillum sp. Group II UBA|Rep: Putative RNA-processing exonuclease - Leptospirillum sp. Group II UBA Length = 479 Score = 55.6 bits (128), Expect = 9e-07 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Frame = +3 Query: 216 TPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAVLISHSDPLHLGALPY 386 T C++L +D F+ L+DCG + D +F LK +SI AV+++H+ H G LP Sbjct: 13 TGSCHLLDVDGFRILIDCGLFQGEDELFSSNLKPFGFEPSSISAVILTHAHLDHCGRLPT 72 Query: 387 AVGKLGLSCPIYATLPVYKMGQMFMYD 467 V + G P+YAT P + ++ ++D Sbjct: 73 LV-RQGFRGPVYATSPTRYLTEIVLWD 98 >UniRef50_A4CGY6 Cluster: Putative uncharacterized protein; n=4; Flavobacteriales|Rep: Putative uncharacterized protein - Robiginitalea biformata HTCC2501 Length = 458 Score = 55.2 bits (127), Expect = 1e-06 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAVLIS 350 I +H L AG T Y+L + K L+DCG + + +K + +V IDAVL++ Sbjct: 6 INIHFLGAAGTVTGSKYLLDTGDRKILIDCGLFQGLKELRLKNWEYPPVNVTEIDAVLLT 65 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497 H H G LP V K G PIY T P + ++ + D + + +E Sbjct: 66 HGHLDHTGYLPRLV-KQGFKGPIYGTYPTLDIAKIILNDSAKIQEQEAE 113 >UniRef50_Q9U3K2 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 608 Score = 55.2 bits (127), Expect = 1e-06 Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 9/154 (5%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356 GAG++ C ++ I ++DCG D +F D +I R + +D V+ISH Sbjct: 14 GAGQDVGRSCILITIGGKNIMVDCGMHMGYQDDRRFPDFSYIGGGGRLTDYLDCVIISHF 73 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNV-SEFDLFTLDDVDMA 533 H G+LP+ +G PIY T P + + + D + ++ E + FT DD+ Sbjct: 74 HLDHCGSLPHMSEIVGYDGPIYMTYPTKAICPVLLEDYRKVQCDIKGETNFFTSDDIKNC 133 Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 ++V ++ I + + L I AGH LG Sbjct: 134 MKKVVGCALHEIIHVDNE---LSIRAFYAGHVLG 164 >UniRef50_Q8GUU3 Cluster: FEG protein; n=8; Magnoliophyta|Rep: FEG protein - Arabidopsis thaliana (Mouse-ear cress) Length = 613 Score = 54.8 bits (126), Expect = 2e-06 Identities = 44/160 (27%), Positives = 71/160 (44%), Gaps = 10/160 (6%) Frame = +3 Query: 186 LHCLS-GAGEET-PPCYVLQIDEFKFLLDCGWDEKFD-------MVFIKELKRHVNSIDA 338 + CL GAG+E C V+ I+ K + DCG D I + N+I Sbjct: 3 IDCLVLGAGQEIGKSCVVVTINGKKIMFDCGMHMGCDDHNRYPNFSLISKSGDFDNAISC 62 Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAH-KNVSEFDLFTL 515 ++I+H H+GALPY G + PIY + P + + + D + E +LFT Sbjct: 63 IIITHFHMDHVGALPYFTEVCGYNGPIYMSYPTKALSPLMLEDYRRVMVDRRGEEELFTT 122 Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + +++ + Q+I++ L+I AGH LG Sbjct: 123 THIANCMKKVIAIDLKQTIQVDE---DLQIRAYYAGHVLG 159 >UniRef50_A6NEN7 Cluster: Uncharacterized protein CPSF3L; n=16; Theria|Rep: Uncharacterized protein CPSF3L - Homo sapiens (Human) Length = 277 Score = 54.4 bits (125), Expect = 2e-06 Identities = 39/136 (28%), Positives = 65/136 (47%), Gaps = 9/136 (6%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356 GAG++ C ++ I +LDCG D +F D +I + R + +D V+ISH Sbjct: 10 GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 69 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ-AHKNVSEFDLFTLDDVDMA 533 H GALPY +G PIY T P + + + D + A E + FT + Sbjct: 70 HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDC 129 Query: 534 FDRIVQLKYNQSIEMK 581 ++V + +Q++++K Sbjct: 130 MKKVVAVHLHQTVQIK 145 >UniRef50_A4XI93 Cluster: Beta-lactamase domain protein; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Beta-lactamase domain protein - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 821 Score = 54.0 bits (124), Expect = 3e-06 Identities = 41/148 (27%), Positives = 66/148 (44%), Gaps = 1/148 (0%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLG 374 L GA E C +++ LLD G K D + +L R + D LISH+ H+G Sbjct: 6 LGGAKEVGASCVLIKAGGKNILLDSGIRMKEDKLPNLQLLRELGGADVCLISHAHLDHIG 65 Query: 375 ALPYAVGKLGLSCPIYATLPVYKMGQMFMYD-LYQAHKNVSEFDLFTLDDVDMAFDRIVQ 551 +LP + + Y P + ++ +YD L E ++ +V+ DR + Sbjct: 66 SLP-LIAREYPHIFFYTNQPTKDLIKVLLYDSLKIMDAKEDEIPIYAEKNVEDLLDRTIT 124 Query: 552 LKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +N + E G+++T PAGH LG Sbjct: 125 YGFNYTFEPLE---GIKVTFFPAGHILG 149 >UniRef50_A4S2M5 Cluster: Predicted protein; n=4; Viridiplantae|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 767 Score = 54.0 bits (124), Expect = 3e-06 Identities = 37/151 (24%), Positives = 71/151 (47%), Gaps = 6/151 (3%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKF----DMVFIKELKRHVNSIDAVLISHSDPL 365 GAG E C + + + + DCG + + + E+ + +DA+ ++H Sbjct: 18 GAGSEVGRSCVIARYKQKTLMFDCGIHPGYAGLASLPYFDEID--LADVDALFVTHFHLD 75 Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD-LFTLDDVDMAFDR 542 H A+P+ G+ + I+ T P + M M D + KN + LF D++ + + Sbjct: 76 HCAAVPFLCGRTDFNGRIFMTHPTKAIYHMLMQDFCRLLKNQEPSEQLFGEKDLEASMKK 135 Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 I + ++Q +++ G+++TP AGH LG Sbjct: 136 IEVIDFHQEVDVD----GVKVTPYRAGHVLG 162 >UniRef50_Q5TA51 Cluster: Cleavage and polyadenylation specific factor 3-like; n=2; Homo sapiens|Rep: Cleavage and polyadenylation specific factor 3-like - Homo sapiens (Human) Length = 308 Score = 54.0 bits (124), Expect = 3e-06 Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 9/139 (6%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356 GAG++ C ++ I +LDCG D +F D +I + R + +D V+ISH Sbjct: 29 GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 88 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ-AHKNVSEFDLFTLDDVDMA 533 H GALPY +G PIY T P + + + D + A E + FT + Sbjct: 89 HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDC 148 Query: 534 FDRIVQLKYNQSIEMKGKG 590 ++V + +Q+++++ G Sbjct: 149 MKKVVAVHLHQTVQVRFPG 167 >UniRef50_Q4UDL0 Cluster: Putative uncharacterized protein; n=3; Theileria|Rep: Putative uncharacterized protein - Theileria annulata Length = 830 Score = 53.6 bits (123), Expect = 4e-06 Identities = 30/110 (27%), Positives = 57/110 (51%), Gaps = 6/110 (5%) Frame = +3 Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKL-----GLSCP-I 419 LL+CGW F + K++ ++D +LI+ D LH GAL + + G S P I Sbjct: 39 LLNCGWSLDFSEEKLNLYKKYAQNVDVILITDGDFLHSGALLWLTSRFLTELKGKSIPKI 98 Query: 420 YATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQS 569 T YK + + D+ + ++F +++DD+++ V+L+Y+++ Sbjct: 99 LCTEGTYKFMRASLIDVLENVTFSTDFGYYSMDDLELLDSNCVKLRYSET 148 >UniRef50_Q9YEQ9 Cluster: Putative exonuclease; n=1; Aeropyrum pernix|Rep: Putative exonuclease - Aeropyrum pernix Length = 671 Score = 53.6 bits (123), Expect = 4e-06 Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 6/161 (3%) Frame = +3 Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD------EKFDMVFIKELKRHVNSI 332 T +++ L GE ++ E K LLD G + + + E + V+ + Sbjct: 189 TRHVRVVGLGSFGEVGRSAILVDTGESKVLLDAGLSPSGYGPDSYPYYWSPEFR--VDEL 246 Query: 333 DAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFT 512 DAV+ISH+ H+G LP K G P+YAT P + + + DL + F Sbjct: 247 DAVVISHAHLDHVGTLPLLF-KYGFRGPVYATPPTRDIMIIVLRDLINLMRKAQGEPPFE 305 Query: 513 LDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 DV+ A R++ + YN ++ +++T + AGH LG Sbjct: 306 PRDVEKALTRLIPVNYNTVTDV---APDIKMTFINAGHILG 343 >UniRef50_Q5BEP0 Cluster: Endoribonuclease ysh1; n=15; Pezizomycotina|Rep: Endoribonuclease ysh1 - Emericella nidulans (Aspergillus nidulans) Length = 884 Score = 53.6 bits (123), Expect = 4e-06 Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 8/160 (5%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD---EKFDMV-FIKELKRHVNSIDAVLI 347 + +CL G E C+++Q +LD G E F + F E ++++D +LI Sbjct: 24 LAFYCLGGGNEVGRSCHIIQYKGKTVMLDAGMHPAKEGFSALPFFDEFD--LSTVDILLI 81 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD----LFTL 515 SH H ALPY + K ++ T + + + D + + S D L+T Sbjct: 82 SHFHVDHSSALPYVLSKTNFKGRVFMTHATKAIYKWLIQDNVRVNNTASSSDQRTTLYTE 141 Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 D I + +N + + +RITP PAGH LG Sbjct: 142 HDHLSTLPLIETIDFNTTHTIN----SIRITPYPAGHVLG 177 >UniRef50_Q6FW78 Cluster: Candida glabrata strain CBS138 chromosome D complete sequence; n=1; Candida glabrata|Rep: Candida glabrata strain CBS138 chromosome D complete sequence - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 843 Score = 53.2 bits (122), Expect = 5e-06 Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 9/144 (6%) Frame = +3 Query: 231 VLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN---SIDAVLISHSDPLHLGALPYA---- 389 +L+ D LLD GW + + + + N +D +LIS LGA + Sbjct: 19 ILRFDNVTILLDPGWSS-YKVSYEDSVAFWSNIIAEVDIILISQPTTECLGAYTFLYYNF 77 Query: 390 VGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL--FTLDDVDMAFDRIVQLKYN 563 + +YATLPV +G++ + Y + + +DDV+ AFD I LKY+ Sbjct: 78 ISHFISHIQVYATLPVANLGRVSTIEFYVTKGIIGPYQTNQLDIDDVEKAFDFIDVLKYS 137 Query: 564 QSIEMKGKGLGLRITPLPAGHSLG 635 Q ++++ K GL + +G++ G Sbjct: 138 QLVDLRSKYDGLSLFAYNSGYAPG 161 >UniRef50_Q4Q2K1 Cluster: Cleavage and polyadenylation specificity factor, putative; n=7; Trypanosomatidae|Rep: Cleavage and polyadenylation specificity factor, putative - Leishmania major Length = 756 Score = 52.8 bits (121), Expect = 7e-06 Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 4/151 (2%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCG---WDEKFDMV-FIKELKRHVNSIDAVLISHSDP 362 + GE C V+Q +LDCG D + F +K + ID VLI+H Sbjct: 31 IGSGGEVGRSCVVVQYKGRGVMLDCGNHPAKSGLDSLPFFDSIK--CDEIDVVLITHFHL 88 Query: 363 LHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDR 542 H GALPY + ++ T +M M D + S DL T + + DR Sbjct: 89 DHCGALPYFCNQTSFKGRVFMTSATKAFYKMVMNDFLRIGAGAS--DLVTSEWLQSTIDR 146 Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 I ++Y++ + + G+ P AGH LG Sbjct: 147 IETVEYHEEVTVN----GISFQPFNAGHVLG 173 >UniRef50_A2FCF8 Cluster: RNA-metabolising metallo-beta-lactamase family protein; n=1; Trichomonas vaginalis G3|Rep: RNA-metabolising metallo-beta-lactamase family protein - Trichomonas vaginalis G3 Length = 679 Score = 52.8 bits (121), Expect = 7e-06 Identities = 41/151 (27%), Positives = 74/151 (49%), Gaps = 6/151 (3%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDPL 365 GAG+E C +L+ + +LDCG ++ + FI + ID +LI+H Sbjct: 17 GAGQEVGRSCIILKYHRKRVMLDCGIHPAYENFGGLPFIDAIDPA--KIDVLLITHFHID 74 Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD-LYQAHKNVSEFDLFTLDDVDMAFDR 542 H+ A+P+ + + S P + T + + + D + + + E +LFT DV + Sbjct: 75 HITAVPWFLTQTNFSGPCFMTHTTKTISKTLLVDYVGVSGRGSEEPNLFTRADVANVQNM 134 Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 I + Y+Q++ + G+++T PAGH LG Sbjct: 135 ITAVNYHQTVTHQ----GIKMTCYPAGHVLG 161 >UniRef50_A0BGT5 Cluster: Chromosome undetermined scaffold_106, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_106, whole genome shotgun sequence - Paramecium tetraurelia Length = 690 Score = 52.8 bits (121), Expect = 7e-06 Identities = 40/151 (26%), Positives = 65/151 (43%), Gaps = 6/151 (3%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWD---EKFDMVFIKELKR--HVNSIDAVLISHSDP 362 GAG E C +LQ E + + DCG E ++ + + + ID +LI+H Sbjct: 14 GAGNEVGRSCILLQFQEKQIMFDCGIHMNKENKGVMALPYFNKIDKIEDIDLILITHFHL 73 Query: 363 LHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDR 542 H GALPY + IY T P ++ + + D + DL ++ + Sbjct: 74 DHCGALPYFLKNYKFKGKIYMTTPTKEIYGLVLKDSIKVKSEDFSQDLINEQSIEQSLKN 133 Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 I + Y+Q I + G+++ AGH LG Sbjct: 134 IDCIDYDQEIHYQ----GIKLKCYNAGHVLG 160 >UniRef50_A1RWY8 Cluster: Beta-lactamase domain protein; n=1; Thermofilum pendens Hrk 5|Rep: Beta-lactamase domain protein - Thermofilum pendens (strain Hrk 5) Length = 639 Score = 52.0 bits (119), Expect = 1e-05 Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 3/138 (2%) Frame = +3 Query: 231 VLQIDEFKFLLDCGWDE--KFDMVFIKELKRH-VNSIDAVLISHSDPLHLGALPYAVGKL 401 ++Q E LLD G D + + +L + S+DAV+I+H+ H+GALP + K Sbjct: 197 LVQTPEANILLDAGLKPTGNGDELPLFDLPEFDLESLDAVVITHAHLDHVGALP-VLFKY 255 Query: 402 GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMK 581 G P+Y T P + ++ D + + + +L+++ DV+ L Y + ++ Sbjct: 256 GYKGPVYMTEPTLHLSKLLFEDYIKVAQREGKNELYSMRDVNSLLLNTYTLSYGEVTDIA 315 Query: 582 GKGLGLRITPLPAGHSLG 635 + +R+T AGH LG Sbjct: 316 PE---IRLTFYRAGHILG 330 >UniRef50_A5ZRP6 Cluster: Putative uncharacterized protein; n=4; Bacteria|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 539 Score = 51.6 bits (118), Expect = 2e-05 Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 14/166 (8%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359 +K+ + E T CY L+ KFL+DCG ++ D +++ + +D VL++H+ Sbjct: 1 MKITFIGATHEVTGSCYYLEAAGKKFLVDCGMEQGPDYYENQDIPVKGSDLDFVLLTHAH 60 Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD-----LYQA--------HKNVSEF 500 H G LP A+ G PIYAT + + + D +++A + EF Sbjct: 61 MDHSGNLP-AIYAKGFQGPIYATQATCHLCDIMLRDSAHIQMFEAEWRNRKGRRQGKPEF 119 Query: 501 -DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +T++D V Y ++I+ +G+ +R + AGH LG Sbjct: 120 VPAYTMEDAMGVIQNFVPCPYEKTIK-PAEGISVRF--VDAGHLLG 162 >UniRef50_A3HWA3 Cluster: Metallo-beta-lactamase family protein; n=1; Algoriphagus sp. PR1|Rep: Metallo-beta-lactamase family protein - Algoriphagus sp. PR1 Length = 482 Score = 50.8 bits (116), Expect = 3e-05 Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 16/163 (9%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRH---VNSIDAVLISHSDPL 365 L GAG T Y++ + +F+FL+DCG + + + + ++A++++H+ Sbjct: 24 LGGAGAVTGSKYLIDLGDFEFLVDCGLYQGAKNLRKRNWDKFPMPPTDMEAIILTHAHLD 83 Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF-------------DL 506 H+G LP V K G PIY T ++ ++ + D + + +E+ L Sbjct: 84 HVGYLPKLV-KQGFKGPIYCTEATAELAKILLLDSGKLQEEEAEYARKKGYSRHESPEPL 142 Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +T DD + F ++V ++ ++ + +T AGH LG Sbjct: 143 YTRDDAESVFPQLVPQQFETPFQINP---NVSVTYYHAGHILG 182 >UniRef50_A2D958 Cluster: RNA-metabolising metallo-beta-lactamase family protein; n=1; Trichomonas vaginalis G3|Rep: RNA-metabolising metallo-beta-lactamase family protein - Trichomonas vaginalis G3 Length = 588 Score = 50.8 bits (116), Expect = 3e-05 Identities = 44/156 (28%), Positives = 66/156 (42%), Gaps = 5/156 (3%) Frame = +3 Query: 183 KLHCLSGAGEETPPCYVLQIDEFKFLLDCG-----WDEKFDMVFIKELKRHVNSIDAVLI 347 +L C GE +++I K LLDCG DEK + ++ +D VLI Sbjct: 14 QLICFGAGGEVGRSSILVEIGSKKVLLDCGVNFTATDEKDRLPAYQD---PFPKVDLVLI 70 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 SH HL A+PY L P+Y T + QM M + V+E + +D+ Sbjct: 71 SHIHTDHLAAVPYLTEVLKCQAPVYMT----RASQMMMPIMLDDFLKVTENPPYKAEDLT 126 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +I +++ E G+ + PAGH LG Sbjct: 127 NCKPKIKVVEFYSRFE---AAPGIFVQAFPAGHILG 159 >UniRef50_Q6CNJ8 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome E of strain NRRL Y- 1140 of Kluyveromyces lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome E of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 812 Score = 50.8 bits (116), Expect = 3e-05 Identities = 36/142 (25%), Positives = 71/142 (50%), Gaps = 7/142 (4%) Frame = +3 Query: 231 VLQIDEFKFLLDCGWDEKFDMVFIKEL-KRHVNSIDAVLISHSDPLHLGALPYAVGKL-- 401 +++ + LLD GW+ + +E ++++ +D VLIS LG+ + Sbjct: 19 IVRFNNVIVLLDPGWNGEGSYEECEEFWTQYISEVDIVLISQPTIECLGSYAMMFKQFLP 78 Query: 402 --GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFDRIVQLKYNQS 569 +Y TLPV +G++ DL + + F + L+D++ +FD I +KY+Q+ Sbjct: 79 HFRSRIQVYGTLPVSNLGRVNSVDLLTSVGILGPFSNAVMDLEDIESSFDLIETVKYSQT 138 Query: 570 IEMKGKGLGLRITPLPAGHSLG 635 +++K K GL + +G++ G Sbjct: 139 VDLKNKFDGLSLEAHNSGYAPG 160 >UniRef50_Q2LYC2 Cluster: Metallo-beta-lactamase protein; n=6; Deltaproteobacteria|Rep: Metallo-beta-lactamase protein - Syntrophus aciditrophicus (strain SB) Length = 541 Score = 50.4 bits (115), Expect = 4e-05 Identities = 43/170 (25%), Positives = 74/170 (43%), Gaps = 17/170 (10%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV---NSIDAVLI 347 I+K+ L A T CY+L+ +F +DCG + + + + + I+ LI Sbjct: 6 IMKIKFLGAARTVTGSCYILETQGHRFAIDCGMHQGNEEIEKRNWNVELYEPEKIEFFLI 65 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF--------- 500 +H+ H G LP V K G PIYAT P + ++ + D + +++ Sbjct: 66 THAHIDHTGLLPRLVQK-GFRGPIYATQPTVDLLRILLLDSAHIQEMEAQWKSRKRLRFG 124 Query: 501 -----DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L+T D + F + + Y++ E GL++ + AGH LG Sbjct: 125 EKRVGPLYTQRDAEAVFPMLKSVSYDKPFE---PFPGLKVNFMDAGHILG 171 >UniRef50_A5N1D0 Cluster: Putative uncharacterized protein; n=1; Clostridium kluyveri DSM 555|Rep: Putative uncharacterized protein - Clostridium kluyveri DSM 555 Length = 832 Score = 50.4 bits (115), Expect = 4e-05 Identities = 36/125 (28%), Positives = 58/125 (46%), Gaps = 3/125 (2%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELK--RHVNSIDAVLISHSDPLH 368 L GA E C +++I L+DCG + + + K + IDA++ISHS H Sbjct: 10 LGGAREVGGSCILVKIYNRNILMDCGIRQSSSKDALPDFKSIQEQGGIDAIIISHSHMDH 69 Query: 369 LGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKN-VSEFDLFTLDDVDMAFDRI 545 +G+LP + L+ IYAT + ++ +YD + N E L+ DV + I Sbjct: 70 IGSLPIISKEYPLA-RIYATKMTKDLMRVLLYDSLKIMNNREGEIPLYAESDVKNMLNSI 128 Query: 546 VQLKY 560 + Y Sbjct: 129 FPINY 133 >UniRef50_Q06224 Cluster: Endoribonuclease YSH1; n=10; Fungi/Metazoa group|Rep: Endoribonuclease YSH1 - Saccharomyces cerevisiae (Baker's yeast) Length = 779 Score = 50.4 bits (115), Expect = 4e-05 Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 12/167 (7%) Frame = +3 Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDA 338 T+ K L G+ E C++LQ +LD G + + F E ++ +D Sbjct: 6 TTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFD--LSKVDI 63 Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ--------AHKNVS 494 +LISH H +LPY + + ++ T P + + + D + + Sbjct: 64 LLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTK 123 Query: 495 EFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + LF+ +D+ +FD+I + Y+ ++++ G++ T AGH LG Sbjct: 124 DEGLFSDEDLVDSFDKIETVDYHSTVDVN----GIKFTAFHAGHVLG 166 >UniRef50_Q95PY8 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 707 Score = 50.0 bits (114), Expect = 5e-05 Identities = 40/152 (26%), Positives = 71/152 (46%), Gaps = 7/152 (4%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMV----FIKELKRHVNSIDAVLISHSDPL 365 G+G+E C++L+ + +LDCG V F+ ++ + +ID +LI+H Sbjct: 17 GSGQEVGRSCHLLEYKGKRVMLDCGVHPGLHGVDALPFVDFVE--IENIDLLLITHFHLD 74 Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK--NVSEFDLFTLDDVDMAFD 539 H GALP+ + K + T + +M + D + K L+T DD++ + Sbjct: 75 HCGALPWLLQKTAFQGKCFMTHATKAIYRMLLGDYVRISKYGGPDRNQLYTEDDLEKSMA 134 Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +I + + + E+ G+R P AGH LG Sbjct: 135 KIETIDFREQKEVN----GIRFWPYVAGHVLG 162 >UniRef50_A7TEK7 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 821 Score = 50.0 bits (114), Expect = 5e-05 Identities = 37/143 (25%), Positives = 68/143 (47%), Gaps = 8/143 (5%) Frame = +3 Query: 231 VLQIDEFKFLLDCGWDEKFDMVF--IKELKRHVNSIDAVLISHSDPLHLGA---LPYA-V 392 +++ D L+D W+ K IK + +D +L+S LGA L Y V Sbjct: 19 IVRFDNVTILIDPSWNGKNVSYADSIKYWSTIIPEVDIILLSQPSLECLGAYSMLYYNFV 78 Query: 393 GKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL--FTLDDVDMAFDRIVQLKYNQ 566 +YATLPV +G++ + + Y + ++ L+D++ +FD I +KY+Q Sbjct: 79 SHFVSRIDVYATLPVSNLGRISVIEQYACAGIIGPYETNEMDLEDIEKSFDNIKTVKYSQ 138 Query: 567 SIEMKGKGLGLRITPLPAGHSLG 635 ++++ K GL + +G + G Sbjct: 139 LVDLRSKFDGLTLVAYNSGVNAG 161 >UniRef50_Q58633 Cluster: Uncharacterized protein MJ1236; n=16; Euryarchaeota|Rep: Uncharacterized protein MJ1236 - Methanococcus jannaschii Length = 634 Score = 49.6 bits (113), Expect = 6e-05 Identities = 37/157 (23%), Positives = 68/157 (43%), Gaps = 5/157 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-----WDEKFDMVFIKELKRHVNSIDAVL 344 I++ L GA E C +Q + + L+DCG D+ F E + +DAV+ Sbjct: 180 IRVSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACEDKAFPHFDAPEFS--IEDLDAVI 237 Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDV 524 ++H+ H G +P + + G P+Y T P + + D + K + +T D+ Sbjct: 238 VTHAHLDHCGFIP-GLFRYGYDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTSKDI 296 Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + + Y + ++ +++T AGH LG Sbjct: 297 KTCVKHTIPIDYGVTTDISPT---IKLTLHNAGHVLG 330 >UniRef50_Q24CH6 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 749 Score = 49.2 bits (112), Expect = 8e-05 Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 10/141 (7%) Frame = +3 Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVG-----KLGL 407 +E LLDCG + D + + +D +L+SH ++GALP+ + G Sbjct: 25 EEIYILLDCGLNSNMDFTAYWQNIEKLKKVDMILLSHVGAEYVGALPFLLNNKQIMSQGK 84 Query: 408 SCPIYATLPVYKMGQMFMYDLY-QAHKNVSEFDLF----TLDDVDMAFDRIVQLKYNQSI 572 + IY+T PV K+G Y+ Y SE + + +A+DR +++ Q Sbjct: 85 NIRIYSTTPVMKLGMFNSYNQYLNTMMLASEEETLVTEKSFQKFYIAYDRCKVIQFFQKK 144 Query: 573 EMKGKGLGLRITPLPAGHSLG 635 + K + I+P G++LG Sbjct: 145 VVHIKDKDIIISPNCIGNTLG 165 >UniRef50_A7DQ83 Cluster: Beta-lactamase domain protein; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Beta-lactamase domain protein - Candidatus Nitrosopumilus maritimus SCM1 Length = 646 Score = 49.2 bits (112), Expect = 8e-05 Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 5/157 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD----EKFD-MVFIKELKRHVNSIDAVL 344 + L+ L G G+ +L E K L+DCG + D + L ++ +DAV+ Sbjct: 189 VSLYTLGGFGQVGRSSLLLSTPESKILIDCGINPGARSPMDAFPRLDSLNLTLDDLDAVV 248 Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDV 524 I H+ H G LP + K G PIY T P M + D + +++ DV Sbjct: 249 IGHAHLDHTGFLP-TLCKYGYKGPIYCTEPTLPMMNLIQLDAIKVAAAQGRTPIYSERDV 307 Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + + L Y ++ +++ AGH LG Sbjct: 308 KQIMRQTITLPYGTVTDISP---DIKLVLANAGHILG 341 >UniRef50_Q5CRW9 Cluster: CPSF metallobeta-lactamase; n=2; Cryptosporidium|Rep: CPSF metallobeta-lactamase - Cryptosporidium parvum Iowa II Length = 751 Score = 48.8 bits (111), Expect = 1e-04 Identities = 49/175 (28%), Positives = 77/175 (44%), Gaps = 30/175 (17%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW-----DEK----FDMVFIKELKRHVNS-IDAVLI 347 GAG++ C + +I + DCG DE+ F ++ +N ID V+I Sbjct: 11 GAGQDVGRSCIIAKIGSKTVMFDCGMHMGFKDERKYPDFRLISATLDPLIINEYIDLVII 70 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD--------LYQAHKNV---- 491 SH H GALP+ K+G PI T P + + + D L NV Sbjct: 71 SHYHLDHCGALPFFTEKIGYKGPIVMTYPTKSVSSVLLSDCCKIMEQKLLLQKTNVDVAP 130 Query: 492 -------SEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +E+ FT+ DV +++ ++ +Q+I + G++ITP AGH LG Sbjct: 131 PNETVYNNEYGFFTVSDVWSCMEKVKAIQLHQTIVIS----GIKITPYYAGHVLG 181 >UniRef50_A1RTJ6 Cluster: Beta-lactamase domain protein; n=1; Pyrobaculum islandicum DSM 4184|Rep: Beta-lactamase domain protein - Pyrobaculum islandicum (strain DSM 4184 / JCM 9189) Length = 640 Score = 48.4 bits (110), Expect = 1e-04 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCG-----WDEKFDMVFIKELKRHVNSIDAVLISHSD 359 L A E ++ E LLDCG +DE F ++ ++ R +DAV+++H+ Sbjct: 185 LGAAMEVGRSAILVSTTESNILLDCGLKPGQYDEDFPLLDAVDIDR----LDAVVLTHAH 240 Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFD 539 H+G LP+ + K G P+Y T P + + D + + F+ DV+ Sbjct: 241 MDHVGCLPF-LYKYGYRGPVYMTDPTKYQTFILLMDYIELKEREGLEPAFSRADVESVIY 299 Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + L Y + ++ +++T AGH +G Sbjct: 300 HTITLDYEEVTDI---APDVKLTFYDAGHEIG 328 >UniRef50_Q5KCZ0 Cluster: Endoribonuclease YSH1; n=2; cellular organisms|Rep: Endoribonuclease YSH1 - Cryptococcus neoformans (Filobasidiella neoformans) Length = 773 Score = 48.4 bits (110), Expect = 1e-04 Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 11/156 (7%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMV----FIKELKRHVNSIDAVLISHSDPL 365 GAG+E C V++ K + D G + FI EL +++DA+LI+H Sbjct: 35 GAGQEVGRSCCVIEHRGKKIVCDAGLHPAQPGIGALPFIDELDW--STVDAMLITHFHVD 92 Query: 366 HLGALPYAVGKL------GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527 H ALPY + K G +AT +Y + M L + + S L+ DV Sbjct: 93 HAAALPYIMEKTNFKDGNGKVYMTHATKAIYGLTMMDTVRLNDQNPDTSG-RLYDEADVQ 151 Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 ++ + + Y+Q I + G GLR TP AGH LG Sbjct: 152 SSWQSTIAVDYHQDIVIAG---GLRFTPYHAGHVLG 184 >UniRef50_UPI00015BA9DD Cluster: beta-lactamase domain protein; n=1; Ignicoccus hospitalis KIN4/I|Rep: beta-lactamase domain protein - Ignicoccus hospitalis KIN4/I Length = 652 Score = 48.0 bits (109), Expect = 2e-04 Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 3/158 (1%) Frame = +3 Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE-KFDMV--FIKELKRHVNSIDAV 341 T+ +++ L E +L+ E K LLD G + +D F K + ++ +DAV Sbjct: 179 TNYVRITALGAFKEVGRSAILLETKESKVLLDFGANVGSYDPQKHFPKVEEVPIDELDAV 238 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDD 521 +++H+ H G +P+ + K G P+Y T P + + D + + + +T D Sbjct: 239 IVTHAHLDHCGLVPW-LYKYGYRGPVYVTQPTRDLMYLVQKDYIEVARKEGKPVPYTESD 297 Query: 522 VDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 ++ R + L Y E+ +++T AGH LG Sbjct: 298 INSMLLRTIALNYG---EVTDVAPDIKLTFYNAGHILG 332 >UniRef50_Q0LL72 Cluster: Beta-lactamase-like; n=3; Herpetosiphon aurantiacus ATCC 23779|Rep: Beta-lactamase-like - Herpetosiphon aurantiacus ATCC 23779 Length = 786 Score = 48.0 bits (109), Expect = 2e-04 Identities = 45/163 (27%), Positives = 72/163 (44%), Gaps = 10/163 (6%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE-----KFDMVFIKELKRHVNSIDAV 341 +I H GA E C +L++ L+D G + ++ LK +DA+ Sbjct: 1 MISFHPFGGAQEVGASCGILKLGMRHILVDAGMRPAARPGQSRTPDLEALKGF--PLDAI 58 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD----LYQAH-KNVSEFDL 506 LI+H+ H G LP V L + PIYAT + ++ + D + Q H + E L Sbjct: 59 LITHAHIDHTGCLPL-VASLFPTVPIYATESTIALMRILLLDSARIMEQEHLAHELETPL 117 Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + V RI+ + ++Q + + +T LPAGH LG Sbjct: 118 YDQAMVTETLARIIPVAFHQELRPVAANQEISVTYLPAGHILG 160 >UniRef50_A6C193 Cluster: Exonuclease of the beta-lactamase fold involved in RNA processing; n=1; Planctomyces maris DSM 8797|Rep: Exonuclease of the beta-lactamase fold involved in RNA processing - Planctomyces maris DSM 8797 Length = 464 Score = 48.0 bits (109), Expect = 2e-04 Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 16/168 (9%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV---NSIDAVLIS 350 +K+ L AGE T ++++ D + LLDCG + + R S+DAV +S Sbjct: 1 MKITFLGAAGEVTGSQHLIETDSRRILLDCGLFQGHRQESYLKNSRFAYPPESLDAVFLS 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD---------LYQAHKNVSEF- 500 H H G LP K G P++ T + ++ + D Y A K + Sbjct: 61 HGHMDHCGNLPRLFNK-GFRGPVFCTSATADIAEIMLKDSARIQEEDARYLARKLTDKHP 119 Query: 501 ---DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L++ DDV + +L+Y + E+ G L++ L AGH LG Sbjct: 120 PIEPLYSEDDVTAVAKQFERLEYQEWHEL---GDDLKVRFLDAGHILG 164 >UniRef50_Q9UKF6 Cluster: Cleavage and polyadenylation specificity factor subunit 3; n=53; Eumetazoa|Rep: Cleavage and polyadenylation specificity factor subunit 3 - Homo sapiens (Human) Length = 684 Score = 48.0 bits (109), Expect = 2e-04 Identities = 44/150 (29%), Positives = 70/150 (46%), Gaps = 5/150 (3%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWD---EKFDMVFIKELKRHVNSIDAVLISHSDPLH 368 GAG+E C +L+ K +LDCG E D + +L ID +LISH H Sbjct: 18 GAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAE-IDLLLISHFHLDH 76 Query: 369 LGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD-LFTLDDVDMAFDRI 545 GALP+ + K + T + + + D Y N+S D L+T D++ + D+I Sbjct: 77 CGALPWFLQKTSFKGRTFMTHATKAIYRWLLSD-YVKVSNISADDMLYTETDLEESMDKI 135 Query: 546 VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + +++ E+ G++ AGH LG Sbjct: 136 ETINFHEVKEV----AGIKFWCYHAGHVLG 161 >UniRef50_Q11PK2 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Metallo-beta-lactamase superfamily protein - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 451 Score = 47.2 bits (107), Expect = 3e-04 Identities = 39/157 (24%), Positives = 77/157 (49%), Gaps = 5/157 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD--EKFDMVFIKELKRHVNSIDAVLISH 353 +KL A + T Y+L+ +K L+DCG D ++ ++ + ID V+++H Sbjct: 1 MKLTFWGAARKVTGSMYLLESLGYKILIDCGSDFSDRHKVLTGGLFPFEASEIDLVILTH 60 Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD---LYQAHKNVSEFDLFTLDDV 524 + H G +P A+ + G I +T P ++ ++ D + +A K ++ + D Sbjct: 61 AHVDHSGNIP-ALIRAGYRGQILSTAPTAELSELLFADSAYIQRAEKKIA--NSAPSDYS 117 Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 DR + + +N+ E+ + + +R+TP+ GH LG Sbjct: 118 YKPVDRFIPIAFNKDFELNER-ITVRLTPV--GHILG 151 >UniRef50_Q5TA44 Cluster: Cleavage and polyadenylation specific factor 3-like; n=4; Eutheria|Rep: Cleavage and polyadenylation specific factor 3-like - Homo sapiens (Human) Length = 401 Score = 47.2 bits (107), Expect = 3e-04 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 8/97 (8%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356 GAG++ C ++ I +LDCG D +F D +I + R + +D V+ISH Sbjct: 22 GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 81 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 H GALPY +G PIY T P + + + D Sbjct: 82 HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLED 118 >UniRef50_Q8ZYD9 Cluster: MRNA 3'-end processing factor, conjectural; n=4; Thermoproteaceae|Rep: MRNA 3'-end processing factor, conjectural - Pyrobaculum aerophilum Length = 634 Score = 47.2 bits (107), Expect = 3e-04 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 5/152 (3%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGW-----DEKFDMVFIKELKRHVNSIDAVLISHSD 359 L A E ++ E LLDCG DE+F ++ + ++ R +DAV+++H+ Sbjct: 179 LGAAMEVGRSAILVSTTESNVLLDCGLKPAQNDEEFPLLDLIDIDR----LDAVVLTHAH 234 Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFD 539 H+G LP+ + K G P+Y T P + + D + + ++ D++ Sbjct: 235 MDHVGCLPF-LFKYGYKGPVYMTDPTKYQAFILLSDYVELKEREGLQPSYSKADIETVIY 293 Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + L Y + ++ +++T AGH +G Sbjct: 294 HTITLDYEEVTDI---APDIKLTFYDAGHEIG 322 >UniRef50_Q4PEJ3 Cluster: Endoribonuclease YSH1; n=6; Fungi/Metazoa group|Rep: Endoribonuclease YSH1 - Ustilago maydis (Smut fungus) Length = 880 Score = 47.2 bits (107), Expect = 3e-04 Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 8/153 (5%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMV----FIKELKRHVNSIDAVLISHSDPL 365 GAG+E C VL+ + D G F + FI EL +++DA+LI+H Sbjct: 30 GAGQEVGRSCCVLKYRGKTIVCDTGVHPAFTGIAALPFIDELDW--STVDAILITHFHLD 87 Query: 366 HLGALPYAVGKLGL---SCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAF 536 H AL Y + K +Y T P + + M D + ++ +LF +++ ++ Sbjct: 88 HAAALTYIMEKTNFRDGHGKVYMTHPTKAVYRFLMSDFVRISNAGNDDNLFDENEMLASW 147 Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +I + ++Q + + G GLR T AGH LG Sbjct: 148 RQIEAVDFHQDVSIAG---GLRFTSYHAGHVLG 177 >UniRef50_Q6CAZ0 Cluster: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 799 Score = 46.8 bits (106), Expect = 4e-04 Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 2/94 (2%) Frame = +3 Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGL--SCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500 +++ VL +H++ HLGA A + P Y TLPV MG++ + Y++ +S Sbjct: 41 TLNLVLFTHANAAHLGAYALACKLYPALAAVPAYGTLPVINMGRIATLEAYRSQGLLSS- 99 Query: 501 DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLR 602 + T ++++ FD I +KY Q I G+G+R Sbjct: 100 EHITATEIEIIFDNITSIKYLQPI-----GIGVR 128 >UniRef50_Q7RRQ3 Cluster: Cleavage and polyadenylation specificity factor, 73 kDa subunit; n=7; Plasmodium|Rep: Cleavage and polyadenylation specificity factor, 73 kDa subunit - Plasmodium yoelii yoelii Length = 942 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 2/87 (2%) Frame = +3 Query: 174 SIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKEL--KRHVNSIDAVLI 347 S I + CL GA E C +++ ++ +LDCG F + + ++ ID LI Sbjct: 2 SNINIVCLGGASEVGRSCVIIESEKTSIMLDCGIHPAFMGIGCLPIYDAYDISKIDVCLI 61 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYAT 428 +H H GALPY + K ++ T Sbjct: 62 THFHMDHSGALPYLINKTRFKGRVFMT 88 >UniRef50_A6QXP5 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 925 Score = 46.4 bits (105), Expect = 6e-04 Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 8/155 (5%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDP 362 L G E C+++Q +LD G D + F + ++++D +LISH Sbjct: 30 LGGGNEVGRSCHIIQYKGKTVMLDAGMHPAKDGFAALPFFDDFD--LSTVDILLISHFHL 87 Query: 363 LHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD----LFTLDDVDM 530 H +LPY + K ++ T + + + D + S D L+T D Sbjct: 88 DHSASLPYVLSKTNFRGRVFMTHATKAIYKWLIQDNVRVSNTSSSSDQRTTLYTEQDHLS 147 Query: 531 AFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 I + +N + + +RITP PAGH LG Sbjct: 148 TLSHIEAIDFNTTHTIN----NIRITPFPAGHVLG 178 >UniRef50_Q8KET4 Cluster: Metallo-beta-lactamase superfamily protein; n=9; Bacteria|Rep: Metallo-beta-lactamase superfamily protein - Chlorobium tepidum Length = 469 Score = 46.0 bits (104), Expect = 8e-04 Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 13/152 (8%) Frame = +3 Query: 216 TPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPY 386 T C++L+ + LLDCG + + + + + IDAV++SH H G LP Sbjct: 13 TGSCHILRAAGYTVLLDCGLVQGSREVEALNREPFPFEPSEIDAVVLSHGHIDHSGRLPL 72 Query: 387 AVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF----------DLFTLDDVDMAF 536 V + G PIY ++ ++ + D +N + F L+T+DD Sbjct: 73 LVNR-GFRGPIYTHHGTIELCEILLRDSATLSENDARFMRKHGQRDDEPLYTVDDAQRCV 131 Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSL 632 ++ ++Y + E+ G+ +T L AGH L Sbjct: 132 RQMEGVRYGERREVLP---GIAVTLLDAGHIL 160 >UniRef50_Q73MR4 Cluster: Metallo-beta-lactamase family protein; n=1; Treponema denticola|Rep: Metallo-beta-lactamase family protein - Treponema denticola Length = 470 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRHVNS--IDAVLIS 350 IK + L A E T ++L++D K+L+DCG + K K +V + ++AV+++ Sbjct: 3 IKFYSLGAAEEVTGSKHILEVDGHKYLIDCGAFQGKRAEADKKNRDFNVPAPELEAVILT 62 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 H H G LP +GK G + IYAT + + M D Sbjct: 63 HGHYDHCGLLP-LLGKHGFTGNIYATPATRDIANLVMMD 100 >UniRef50_Q4N0H3 Cluster: Putative uncharacterized protein; n=2; Theileria|Rep: Putative uncharacterized protein - Theileria parva Length = 678 Score = 46.0 bits (104), Expect = 8e-04 Identities = 23/58 (39%), Positives = 31/58 (53%) Frame = +3 Query: 303 KELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ 476 K LK NS+D +ISH H+GALP+ +G S PIY T P + + + D Q Sbjct: 108 KALKNVTNSVDCSVISHFHLDHVGALPFLTEHIGYSGPIYLTYPTRALCPLLLRDSVQ 165 >UniRef50_Q236M0 Cluster: RNA-metabolising metallo-beta-lactamase family protein; n=1; Tetrahymena thermophila SB210|Rep: RNA-metabolising metallo-beta-lactamase family protein - Tetrahymena thermophila SB210 Length = 750 Score = 46.0 bits (104), Expect = 8e-04 Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW----DEKFDMVFIKELKRHVNSIDAVLISHSDPL 365 GAG+E C +L+ + DCG + + + +K + ID + I+H Sbjct: 7 GAGQEVGRSCIILEYKGKTIMFDCGLHMGKNGHASLPYFDNIKP--DQIDIIFITHFHLD 64 Query: 366 HLGALPYAVGKL---GLSCPIYATLPVYKMGQMFMYD-LYQAHKNVSEFDLFTLDDVDMA 533 H ALPY + K G +YAT P + + + D L +N+ L+T DD++ + Sbjct: 65 HCAALPYFIAKTDFDGKKQKVYATSPTRAIYRHVLRDSLTDKSENIK---LYTADDIEKS 121 Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + I + + + +E + ++ PAGH LG Sbjct: 122 MEVINVIDFYEEMEHE----NIKFKCYPAGHVLG 151 >UniRef50_Q8RBU2 Cluster: Predicted exonuclease of the beta-lactamase fold involved in RNA processing; n=4; Clostridia|Rep: Predicted exonuclease of the beta-lactamase fold involved in RNA processing - Thermoanaerobacter tengcongensis Length = 541 Score = 45.6 bits (103), Expect = 0.001 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDAVLIS 350 +K+ L A E T CY+++ + +FL+DCG E D + +E + ID VL++ Sbjct: 1 MKITFLGAAKEVTGSCYLVETENARFLVDCGMFQGGEVEDELNYQEFIFDIKDIDFVLLT 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428 H+ H G +P + K G IYAT Sbjct: 61 HAHIDHSGRIP-VLYKRGYRKRIYAT 85 >UniRef50_Q23NE4 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 747 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/99 (30%), Positives = 54/99 (54%), Gaps = 1/99 (1%) Frame = +3 Query: 282 KFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFM 461 KFD+ F+ + + NSID +LI+ D + L LP+ + L +YAT+PV ++GQ + Sbjct: 112 KFDLTFLNNIDQ--NSIDFILITSIDDIFL--LPFLFQQNKLKAKVYATVPVAQIGQHVL 167 Query: 462 YDLYQAHKNVS-EFDLFTLDDVDMAFDRIVQLKYNQSIE 575 + Y+ +N + DL + ++ + + + Q Y Q E Sbjct: 168 QEYYKLVQNRNRNIDLSSSENKNGQYFQNSQNSYFQESE 206 >UniRef50_A0RXV0 Cluster: Cleavage and polyadenylation specificity factor/metal-dependent RNase; n=1; Cenarchaeum symbiosum|Rep: Cleavage and polyadenylation specificity factor/metal-dependent RNase - Cenarchaeum symbiosum Length = 645 Score = 45.6 bits (103), Expect = 0.001 Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 7/161 (4%) Frame = +3 Query: 174 SIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD-------EKFDMVFIKELKRHVNSI 332 S I L L G G+ C +L + K L+DCG + E + + + ++ + Sbjct: 186 SEISLTALGGFGQVGRSCMLLSTLDSKVLVDCGVNPGAAHPSESYPRLDWAGIT--LDDL 243 Query: 333 DAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFT 512 DAV+I H+ H G LP + K G PIY T P M + D + ++ Sbjct: 244 DAVVIGHAHLDHTGFLP-VLAKYGYRGPIYCTEPTLPMMNLIQLDAIKVATAQGRVPVYA 302 Query: 513 LDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 DV + + L Y ++ +++ AGH LG Sbjct: 303 ERDVRQIMRQAITLPYGTVTDISP---DIKLVLANAGHILG 340 >UniRef50_Q1GJ92 Cluster: Beta-lactamase-like protein; n=4; Rhodobacteraceae|Rep: Beta-lactamase-like protein - Silicibacter sp. (strain TM1040) Length = 356 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/78 (35%), Positives = 42/78 (53%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLG 374 LSG G++ P L ++LLDCG+ + + F + + +DAV ++H H+G Sbjct: 7 LSGIGDKGPAAMRLDTGRHRWLLDCGFGPEANATFDPD---WLIGVDAVFVTHDHIDHIG 63 Query: 375 ALPYAVGKLGLSCPIYAT 428 YAV + GL PIYAT Sbjct: 64 GAAYAV-EAGL--PIYAT 78 >UniRef50_Q8SRZ4 Cluster: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100kDa SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100kDa SUBUNIT - Encephalitozoon cuniculi Length = 639 Score = 44.4 bits (100), Expect = 0.002 Identities = 32/137 (23%), Positives = 67/137 (48%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404 C++L+ID K L++CG DM + + S DA+L++ + +G LPY + + Sbjct: 20 CHMLEIDNTKILVNCGAPYAMDMSMYTPVLPQILSCDAILLTSFNINCIGGLPYVL-RNN 78 Query: 405 LSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKG 584 +++++P+ +G++ + + + S D F+RI ++KY+Q + Sbjct: 79 YYNKVFSSVPIKVLGKICLDEHLRGMGLESSVD-------TGCFERISEIKYSQPTAVN- 130 Query: 585 KGLGLRITPLPAGHSLG 635 + I +G+S+G Sbjct: 131 ---NVEICAYNSGNSIG 144 >UniRef50_Q6BMW3 Cluster: Endoribonuclease YSH1; n=2; Saccharomycetaceae|Rep: Endoribonuclease YSH1 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 815 Score = 44.4 bits (100), Expect = 0.002 Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 20/175 (11%) Frame = +3 Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDA 338 T K L G E C++++ +LD G + F E ++ +D Sbjct: 11 TDDFKFFGLGGCNEVGRSCHIIEYKNKVIMLDAGVHPGLQGLSSLPFYDEYD--LSKVDI 68 Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIY---ATLPVYKM-------------GQMFMYDL 470 +L+SH H +LPY + + ++ AT +Y+ G + Sbjct: 69 LLVSHFHLDHAASLPYVMQHTNFNGRVFMTHATKAIYRWLLSDFVKVTSIGGGSDARLNN 128 Query: 471 YQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + N +L+T DD+ +FDRI + Y+ +IE+ G+R T AGH LG Sbjct: 129 SDPNANTGSSNLYTDDDLMRSFDRIETIDYHSTIELD----GIRFTAYHAGHVLG 179 >UniRef50_A5KD85 Cluster: Cleavage and polyadenylation specifity factor protein, putative; n=2; Plasmodium vivax|Rep: Cleavage and polyadenylation specifity factor protein, putative - Plasmodium vivax Length = 858 Score = 44.0 bits (99), Expect = 0.003 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKEL--KRHVNSIDAVLISH 353 I + CL GA E C +++ +LDCG F + + ++ +D LI+H Sbjct: 4 INIVCLGGASEVGRSCVIIESANRSIMLDCGIHPAFMGIGCLPIYDAYDISKVDLCLITH 63 Query: 354 SDPLHLGALPYAVGKLGLSCPIYAT 428 H GALPY V + +Y T Sbjct: 64 FHMDHSGALPYLVNRTRFKGKVYMT 88 >UniRef50_Q3ZY44 Cluster: Metallo-beta-lactamase family protein; n=3; Dehalococcoides|Rep: Metallo-beta-lactamase family protein - Dehalococcoides sp. (strain CBDB1) Length = 468 Score = 43.6 bits (98), Expect = 0.004 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISH 353 IK+ L A T Y+LQ D + L+DCG ++ + V S++AVL+SH Sbjct: 3 IKIQFLGAAQNVTGSRYLLQTDHTRLLVDCGLYQERHLQNRNWQPFDVPPESLNAVLVSH 62 Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 + H G LP V K G + P+Y T ++ ++ + D Sbjct: 63 AHIDHCGLLPKLV-KDGYNGPVYLTAATAEIARISLAD 99 >UniRef50_Q2YZG4 Cluster: Predicted exonuclease of the beta-lactamase fold involved in RNA processing; n=1; uncultured gamma proteobacterium|Rep: Predicted exonuclease of the beta-lactamase fold involved in RNA processing - uncultured gamma proteobacterium Length = 426 Score = 43.6 bits (98), Expect = 0.004 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 16/119 (13%) Frame = +3 Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD- 503 ++DA+L+SH+ H G +P V K G P+YAT P + Q+ + D AH + D Sbjct: 14 TVDAMLVSHAHMDHSGNIPNLV-KKGFKGPVYATPPTVDLCQLMLRD--SAHLQKKDIDW 70 Query: 504 ---------------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L+++DD + + ++Y++S E+ G+++T AGH LG Sbjct: 71 VNRIRAKHHQPPMEPLYSMDDAEESLHYFQPVEYDKSFEVIP---GVQVTFKEAGHILG 126 >UniRef50_Q7UMQ3 Cluster: Cleavage and polyadenylation specifity factor-related protein; n=1; Pirellula sp.|Rep: Cleavage and polyadenylation specifity factor-related protein - Rhodopirellula baltica Length = 488 Score = 43.2 bits (97), Expect = 0.005 Identities = 46/160 (28%), Positives = 73/160 (45%), Gaps = 4/160 (2%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEE-TPPCYVLQIDEFKFLL-DCGWDEKFDMVFIK--ELKRHVNSID 335 + S++KL GA E T C+ L ID+ + LL DCG + D E++ + I Sbjct: 41 LMSLMKL-VHHGAHEGVTGSCHQLWIDDSQSLLVDCGTFQGEDARKKPNPEIEFSLRGIQ 99 Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515 A+L++H H G +PY + G PI + P K+ + M D + + Sbjct: 100 ALLLTHVHIDHAGRIPYLLA-AGFDHPILCSAPTAKLLPLVMEDALKI--GFTRSKRLIK 156 Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + +V L Y+Q + G G+++ LPAGH LG Sbjct: 157 KFLGQIRKLLVPLPYHQWHDCPG---GVKVRLLPAGHVLG 193 >UniRef50_Q15V20 Cluster: RNA-metabolising metallo-beta-lactamase; n=1; Pseudoalteromonas atlantica T6c|Rep: RNA-metabolising metallo-beta-lactamase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 467 Score = 43.2 bits (97), Expect = 0.005 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 5/81 (6%) Frame = +3 Query: 201 GAGEE-TPPCYVLQIDEF-KFLLDCGWDE---KFDMVFIKELKRHVNSIDAVLISHSDPL 365 GA +E T C++++ F K LLDCG + D + + + SIDAVL+SH+ Sbjct: 8 GAAQEVTGSCHLIESASFGKILLDCGMHQGGSSIDRIGDEGFPFNPASIDAVLLSHAHLD 67 Query: 366 HLGALPYAVGKLGLSCPIYAT 428 H G LP V G + PIY T Sbjct: 68 HSGMLPKLVHD-GFTGPIYCT 87 >UniRef50_Q8TW11 Cluster: Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain; n=1; Methanopyrus kandleri|Rep: Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain - Methanopyrus kandleri Length = 652 Score = 43.2 bits (97), Expect = 0.005 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 8/159 (5%) Frame = +3 Query: 183 KLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD------EKFDMVFIKELKRHVNSIDAVL 344 ++ L G E L +E + LLDCG + + + + E + ++ +DA++ Sbjct: 195 RVSALGGFQEVGRSSLFLHTEESRVLLDCGVNVAANGTDAYPHFNVPEFR--MDDLDAIV 252 Query: 345 ISHSDPLHLGALPYAVGK--LGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLD 518 I+H+ H G LPY + P+Y T P + + + D + + + +T Sbjct: 253 ITHAHLDHCGFLPYFYRHKVIESRVPVYCTPPTRDLMYLLLTDYIKVLEKRGQEPPYTEK 312 Query: 519 DVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 DV R + + Y + ++ + IT AGH LG Sbjct: 313 DVKKVIKRTITIDYREPTDITP---DMSITFYNAGHILG 348 >UniRef50_A5KKJ4 Cluster: Putative uncharacterized protein; n=1; Ruminococcus torques ATCC 27756|Rep: Putative uncharacterized protein - Ruminococcus torques ATCC 27756 Length = 534 Score = 42.7 bits (96), Expect = 0.007 Identities = 32/108 (29%), Positives = 49/108 (45%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359 +KL + A E T C+ LQ L+DCG ++ D+ L N ID V ++H+ Sbjct: 1 MKLTFVGAAHEVTGSCHFLQAAGKNILIDCGMEQGPDLYENPGLPIPENEIDYVFLTHAH 60 Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503 H G LP + K G I+ T + + + D AH + EF+ Sbjct: 61 IDHSGMLP-KLAKNGFKGQIFTTFATADLCNIMLRD--SAH--IQEFE 103 >UniRef50_A3I563 Cluster: Zn-dependent hydrolase, beta-lactamase superfamily protein; n=1; Bacillus sp. B14905|Rep: Zn-dependent hydrolase, beta-lactamase superfamily protein - Bacillus sp. B14905 Length = 356 Score = 42.7 bits (96), Expect = 0.007 Identities = 24/69 (34%), Positives = 32/69 (46%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356 + K+ L G GE C+ ++ LLDCG + HV + AV ISHS Sbjct: 1 MFKIEILGGVGEYGRNCFYIENQGKAILLDCGVMKNSQKTPPAITLNHVEKLKAVFISHS 60 Query: 357 DPLHLGALP 383 H+GALP Sbjct: 61 HIDHVGALP 69 >UniRef50_Q9UXE8 Cluster: MRNA 3'-end polyadenylation factor; n=6; Thermoprotei|Rep: MRNA 3'-end polyadenylation factor - Sulfolobus solfataricus Length = 639 Score = 42.7 bits (96), Expect = 0.007 Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 8/160 (5%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-------WDEK-FDMVFIKELKRHVNSID 335 +++ L G E +++ E K LLD G + EK F + I +LK + +D Sbjct: 183 VRITALGGFLEVGRSAVLVETPESKVLLDVGLNPSANMFGEKLFPKLDIDQLK--MEELD 240 Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515 AV+I+H+ H G +P+ + K G P+Y T+P + + D + + ++ Sbjct: 241 AVVITHAHLDHCGMVPF-LFKYGYEGPVYTTVPTRDIMALMQLDSLDVAEKEGKPIPYSA 299 Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +V + L Y + ++ +R+T AGH LG Sbjct: 300 KEVRKELLHTITLDYGEVTDI---APDIRLTFYNAGHILG 336 >UniRef50_Q5CPX2 Cluster: Cleavage and polyadenylation specifity factor protein, CPSF metallobeta-lactamase; n=2; Cryptosporidium|Rep: Cleavage and polyadenylation specifity factor protein, CPSF metallobeta-lactamase - Cryptosporidium parvum Iowa II Length = 780 Score = 42.3 bits (95), Expect = 0.009 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 14/159 (8%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMVFIKEL--KRHVNSIDAVLISHSDPLHL 371 GAG E C V+ + DCG F + + V++ID LI+H H Sbjct: 30 GAGCEVGRSCVVVSFKGRSVMFDCGIHPAFSGIGSLPVFDAIDVSTIDLCLITHFHLDHS 89 Query: 372 GALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK-----------NVSEFDLFTLD 518 GA PY V + ++ T P + ++ D + +K +S +L+T Sbjct: 90 GATPYFVSLTDFNGKVFMTEPTKAICKLVWQDYARVNKFSAGSIESEEAPLSSINLYTEK 149 Query: 519 DVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 D++ A + + + Q +E+ G+R + AGH LG Sbjct: 150 DIEKAINMTEIIDFRQQVELD----GIRFSCYGAGHVLG 184 >UniRef50_Q97AZ6 Cluster: Cleavage and polyadenylation specificity factor; n=9; Euryarchaeota|Rep: Cleavage and polyadenylation specificity factor - Thermoplasma volcanium Length = 639 Score = 42.3 bits (95), Expect = 0.009 Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 10/162 (6%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG----------WDEKFDMVFIKELKRHVNS 329 ++L L G E ++ K L+DCG WD +++ E++ ++S Sbjct: 180 VRLTALGGHSEVGRSATLVSTKNSKVLIDCGMMNVGPDADPWDAA-PYLYVPEVQP-LSS 237 Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509 IDAV+++H+ H G LP + K G P+Y T P + + D + + + Sbjct: 238 IDAVILTHAHLDHSGLLP-LLFKYGYDGPVYMTQPTRDLAVLLQDDYIKVARMEGGKVPY 296 Query: 510 TLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + + L+Y ++ ++ +R+T AGH LG Sbjct: 297 ESKYIREELKHTITLRYGETTDIT---RDMRLTFYNAGHILG 335 >UniRef50_Q9RZ85 Cluster: Cleavage and polyadenylation specificity factor-related protein; n=2; Deinococcus|Rep: Cleavage and polyadenylation specificity factor-related protein - Deinococcus radiodurans Length = 499 Score = 41.9 bits (94), Expect = 0.012 Identities = 44/175 (25%), Positives = 79/175 (45%), Gaps = 20/175 (11%) Frame = +3 Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAV 341 T +++ A T ++L + L+DCG + D + + + S+DAV Sbjct: 11 TLAMQMQSFGAACTVTGSMHLLTLGGRHLLVDCGLFQGGDELERRNRESFPFEPASLDAV 70 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQM------------FMYDLYQAHK 485 L++H+ H+G LP V +LG P+Y T P + + + DL +A + Sbjct: 71 LLTHAHLDHVGRLPLLV-RLGYRGPVYCTPPTAALAETVLLDSARLQVEGYRQDLRRARR 129 Query: 486 NVSEFD----LFTLDDVDMAFDRI-VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 E + L+ +DV + QL++ +++ + G +R+TP AGH LG Sbjct: 130 QGREDEVPPPLYDEEDVHRTLALLRPQLEFGETVTVAG----VRVTPQRAGHILG 180 >UniRef50_Q6MLH4 Cluster: Predicted exonuclease of the beta-lactamase family; n=2; Proteobacteria|Rep: Predicted exonuclease of the beta-lactamase family - Bdellovibrio bacteriovorus Length = 452 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFI---KELKRHVNSIDAVLISHSDPL 365 L AG T +++ ++ + L+DCG + F + ++ I AV+++H+ Sbjct: 6 LGAAGTVTGSKFLVHNNDTRILVDCGMFQGFKELRELNWEDFPFDPRDIQAVVLTHAHLD 65 Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 H GALP V K G PIY T P ++ ++ + D Sbjct: 66 HCGALPLLV-KKGFKGPIYCTEPTLELTKIILLD 98 >UniRef50_A7QCN8 Cluster: Chromosome chr12 scaffold_78, whole genome shotgun sequence; n=12; Eukaryota|Rep: Chromosome chr12 scaffold_78, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 662 Score = 41.9 bits (94), Expect = 0.012 Identities = 26/104 (25%), Positives = 51/104 (49%) Frame = +3 Query: 324 NSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503 ++ID +L++H H +LPY + K ++ T + ++ + D + K E Sbjct: 42 STIDVLLVTHFHLDHAASLPYFLEKTTFKGRVFMTHATKAIYKLLLSDYVKVSKVSVEDM 101 Query: 504 LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L+ D+ + D+I + ++Q++E+ G+R AGH LG Sbjct: 102 LYDEQDILRSMDKIEVIDFHQTLEVN----GIRFWCYTAGHVLG 141 >UniRef50_Q7QYP3 Cluster: GLP_393_23867_26140; n=1; Giardia lamblia ATCC 50803|Rep: GLP_393_23867_26140 - Giardia lamblia ATCC 50803 Length = 757 Score = 41.9 bits (94), Expect = 0.012 Identities = 48/178 (26%), Positives = 81/178 (45%), Gaps = 26/178 (14%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEF----KFLLDCGW----DEKFDMVFIK-----ELKRH 320 +KL L E C++L +LDCG E D V I+ +L+ + Sbjct: 29 VKLTPLGAGNEVGRSCFILSYQRSGCSGSIMLDCGLHPALSETRDYVAIQALPFFDLEDY 88 Query: 321 VNSIDAVLISHSDPLHLGALPYAV----------GK--LGLSCPIYATLPVYKMGQMFMY 464 V+++ +LI+H H+ ALPY + GK L P+Y T P K+ + + Sbjct: 89 VSTLSLILITHFHNDHIAALPYLLRCLRDRAVKEGKPELHYIPPVYMTAPTLKIFKESVT 148 Query: 465 DLYQAHKNVSEFDLFTLDDVD-MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 D+ +S+ L+T +DV+ MA + + + Q+ + G+ T +PAGH +G Sbjct: 149 DV------ISQTKLYTHEDVEFMAKNTKLLTSFYQTERVN----GISFTAMPAGHVIG 196 >UniRef50_A7AWH8 Cluster: RNA-metabolising metallo-beta-lactamase and metallo-beta-lactamase superfamily domain containing protein; n=1; Babesia bovis|Rep: RNA-metabolising metallo-beta-lactamase and metallo-beta-lactamase superfamily domain containing protein - Babesia bovis Length = 760 Score = 41.9 bits (94), Expect = 0.012 Identities = 20/58 (34%), Positives = 30/58 (51%) Frame = +3 Query: 303 KELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ 476 K L ++ID +ISH H+GALP+ LG P++ T P +G + + D Q Sbjct: 112 KSLNDITSNIDCAIISHFHLDHIGALPFLTEHLGYKGPVFMTYPTRGLGPIMLRDSAQ 169 >UniRef50_Q60355 Cluster: Uncharacterized protein MJ0047; n=6; Methanococcales|Rep: Uncharacterized protein MJ0047 - Methanococcus jannaschii Length = 428 Score = 41.9 bits (94), Expect = 0.012 Identities = 29/113 (25%), Positives = 52/113 (46%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404 C ++ D+ K LLDCG ++ + L + +D V ISH+ H GALP + Sbjct: 16 CIEIKTDKSKILLDCGVKLGKEIEY-PILDNSIRDVDKVFISHAHLDHSGALPVLFHR-K 73 Query: 405 LSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYN 563 + P+ T K+ ++ + D+ + + ++ + DV A + L YN Sbjct: 74 MDVPVITTELSKKLIKVLLKDMVKIAETENKKIPYNNHDVKEAIRHTIPLNYN 126 >UniRef50_UPI00004992E1 Cluster: cleavage and polyadenylation specificity factor subunit, putative; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cleavage and polyadenylation specificity factor subunit, putative - Entamoeba histolytica HM-1:IMSS Length = 452 Score = 41.5 bits (93), Expect = 0.016 Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 2/154 (1%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE-KFDM-VFIKELKRHVNSIDAVLISH 353 +K+H G C V++ E L DCG++ + D+ + + + I A+ I+H Sbjct: 1 MKVHVFGGGKSVGSSCVVVEGKEDAILFDCGYNPVRPDVGIDFSRMNAISSKIRAICITH 60 Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMA 533 H+G LP+ + K + PIY + P + + + D++ + +LF D D Sbjct: 61 FHVDHVGMLPW-LTKF-MDVPIYLSEPTQALLSLIINDIHSGN------NLFCQADFDKC 112 Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 I+Q K K L I + AGH+LG Sbjct: 113 ---ILQCKPIDPTMTKRVTQNLSIRCIYAGHALG 143 >UniRef50_Q3AAG6 Cluster: Metallo-beta-lactamase family protein; n=2; Carboxydothermus hydrogenoformans|Rep: Metallo-beta-lactamase family protein - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 504 Score = 41.5 bits (93), Expect = 0.016 Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 14/166 (8%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIK---ELKRHVNSIDAVLIS 350 ++L A T CY+ + KFL+DCG + + + E + I+ +L++ Sbjct: 1 MELTFFGAADTVTGSCYLFNVAGHKFLVDCGLFQGPKAIKERNYGEFPFNPREIEFILLT 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD--------LYQAHKNVSEFDL 506 H+ H G +P V K G IYAT P + + + D + + ++ + Sbjct: 61 HAHIDHSGLIPKLV-KKGFKGTIYATEPTVDLAAVMLPDSGHVQEMEVERKNRKLRRAGK 119 Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGL---GLRITPLPAGHSLG 635 L + A D L Y Q I ++ GL +T AGH LG Sbjct: 120 PELQPIYTADDAFNALAYFQKIPLETPITPLPGLEVTFFDAGHILG 165 >UniRef50_A3WMD7 Cluster: Predicted exonuclease of the beta-lactamase fold; n=1; Idiomarina baltica OS145|Rep: Predicted exonuclease of the beta-lactamase fold - Idiomarina baltica OS145 Length = 460 Score = 41.5 bits (93), Expect = 0.016 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQID-EFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356 I L L G + T C++ ++ + ++DCG + V+S+ AV I+H+ Sbjct: 10 IHLTHLGGTWQVTGSCHLWHLNAQQTVMIDCGAFQGITQEDDLTPYVDVDSLAAVFITHA 69 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAF 536 H+G LP + LG PIY T + Q+ + D Q + + T + +A Sbjct: 70 HLDHVGRLPQLLA-LGYRGPIYCTAATLALMQLVLGDSLQL-AGIRDESALTAFNTLLA- 126 Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +V +Y Q++++ L +T AGH LG Sbjct: 127 RHVVLCEYGQTVDVLP---SLSVTFEEAGHILG 156 >UniRef50_Q0HMU8 Cluster: RNA-metabolizing metallo-beta-lactamase; n=16; Shewanella|Rep: RNA-metabolizing metallo-beta-lactamase - Shewanella sp. (strain MR-4) Length = 480 Score = 41.1 bits (92), Expect = 0.022 Identities = 51/163 (31%), Positives = 73/163 (44%), Gaps = 18/163 (11%) Frame = +3 Query: 201 GAGEE-TPPCYVLQIDEFKFLLDCGWDE--KFDMVFIKE-LKRHVNSIDAVLISHSDPLH 368 GA EE T C++L I + LLDCG + K D + E +I AV++SH+ H Sbjct: 9 GATEEVTGSCHLLTIAGQQMLLDCGLIQGGKADELRNHERFSFDPQAISAVVLSHAHIDH 68 Query: 369 LGALPYAVGKLGLSCPIY-----ATLPVYKMGQMFMYDLYQAHKN-----VSEFD----L 506 G LP V K G + PIY A L + M + +N E + L Sbjct: 69 SGRLPLLV-KAGYTGPIYTHKATAELCAIMLKDAAMLQVRDTERNNKKRAKHELEPLEPL 127 Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 FT++D + A + V L+Y Q ++ + I AGH LG Sbjct: 128 FTVEDAEQAVTQFVALEYGQVTQVIPH---VDICLSDAGHILG 167 >UniRef50_Q0EST3 Cluster: Beta-lactamase-like; n=2; Thermoanaerobacter ethanolicus|Rep: Beta-lactamase-like - Thermoanaerobacter ethanolicus X514 Length = 616 Score = 41.1 bits (92), Expect = 0.022 Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Frame = +3 Query: 228 YVLQIDEFKFLLDCGWDEKFDMVF---IKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398 Y++ + LLD G K ++ IK L + ID V+I+H H G + + K Sbjct: 218 YLVSYEGINILLDAGALIKDKTLYYNSIKNLPIDIKDIDLVIITHVHLDHSGGIVELLRK 277 Query: 399 LGLSCPIYATLPVYK-MGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIE 575 GL+ PI + P + + Q+F+ + + E ++ D ++FD + S Sbjct: 278 -GLNSPIIISRPTKEILKQIFLRGHTKLEVKIEE-EIINFDSQIISFD----TEEESSFR 331 Query: 576 MKGKGLGLRITPLPAGHSLG 635 +K K + L++ PAGH LG Sbjct: 332 IKNKEVKLKL--FPAGHILG 349 >UniRef50_Q023M0 Cluster: Beta-lactamase domain protein; n=1; Solibacter usitatus Ellin6076|Rep: Beta-lactamase domain protein - Solibacter usitatus (strain Ellin6076) Length = 469 Score = 41.1 bits (92), Expect = 0.022 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE---KFDMVFIKELKRHVNSIDAVLIS 350 +KL AG T ++++ ++LLDCG + K + L +SIDAV++S Sbjct: 1 MKLTFWGAAGTVTGSMHLVETGGKRYLLDCGLAQGRRKEADAKNRNLPFSGSSIDAVVLS 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428 H+ H G LP V K G S PIY+T Sbjct: 61 HAHIDHSGNLPSLV-KHGFSGPIYST 85 >UniRef50_A7HPZ1 Cluster: Beta-lactamase domain protein; n=2; Alphaproteobacteria|Rep: Beta-lactamase domain protein - Parvibaculum lavamentivorans DS-1 Length = 472 Score = 41.1 bits (92), Expect = 0.022 Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 18/168 (10%) Frame = +3 Query: 186 LHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELK-----RHVNSIDAVLIS 350 L L GAG T ++L +D + L+DCG + + ++EL SIDA++++ Sbjct: 24 LTSLGGAGTVTGSKHLLTLDGHRILIDCGLFQ--GLKNLRELNWAPFPVDPRSIDAIVLT 81 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL---------YQAHKNVSE-- 497 H+ H G LP V + G ++AT + + + D Y K+ S+ Sbjct: 82 HAHLDHSGYLPKIV-REGFRGRVFATDTTCNVAALILKDSGYIQEKDADYANRKSYSKHK 140 Query: 498 --FDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L+ + D + A + + Y++++ + G G +T AGH LG Sbjct: 141 PALPLYGVRDAERAVEAFTAVPYHKTVSLPG---GATLTFRHAGHILG 185 >UniRef50_A6FNJ5 Cluster: Beta-lactamase-like protein; n=1; Roseobacter sp. AzwK-3b|Rep: Beta-lactamase-like protein - Roseobacter sp. AzwK-3b Length = 245 Score = 41.1 bits (92), Expect = 0.022 Identities = 20/62 (32%), Positives = 33/62 (53%) Frame = +3 Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380 G+G C+ + +E +FL+DCG M+ +K ++ +ID + I+H H G L Sbjct: 13 GSGGRFNTCFHVATEETRFLIDCGASS---MIALKAMQIDRAAIDTIFITHFHGDHFGGL 69 Query: 381 PY 386 PY Sbjct: 70 PY 71 >UniRef50_A0JWK6 Cluster: Beta-lactamase domain protein; n=2; Bacteria|Rep: Beta-lactamase domain protein - Arthrobacter sp. (strain FB24) Length = 461 Score = 41.1 bits (92), Expect = 0.022 Identities = 39/167 (23%), Positives = 76/167 (45%), Gaps = 16/167 (9%) Frame = +3 Query: 183 KLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLISH 353 +L L T Y+++ + L+DCG + + ++ + +SIDA+L++H Sbjct: 8 QLRFLGATDSVTGSRYLVEAAGKRILVDCGLFQGYKVLRDRNRIPFPVRPDSIDAILLTH 67 Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF----------- 500 + H G +P A+ + G + P+YAT ++ + + D + +++ Sbjct: 68 AHLDHTGYVP-ALVRDGFNGPVYATEGTTELCTLLLPDSGHLQEEEAKYAYEHGSSRHSP 126 Query: 501 --DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L+T D + D + ++ +E+ G G+ T LPAGH LG Sbjct: 127 PVPLYTAADAVRSLDSFREHGFDTPLELGG---GIAATFLPAGHILG 170 >UniRef50_Q2RJ88 Cluster: RNA-metabolising metallo-beta-lactamase; n=5; Bacteria|Rep: RNA-metabolising metallo-beta-lactamase - Moorella thermoacetica (strain ATCC 39073) Length = 536 Score = 40.7 bits (91), Expect = 0.029 Identities = 25/100 (25%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLI 347 +IKL AG T CY+L ++ L+DCG + + + + +IDA+++ Sbjct: 1 MIKLQFCGAAGTVTGSCYLLDTGRYRLLIDCGLFQGSKAIKERNYGPFPFNPGAIDALIL 60 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 +H+ H G +P + G PI+ T ++ ++ + D Sbjct: 61 THAHIDHCGLIP-KLYLQGFKGPIFTTPVTAELARVLLPD 99 >UniRef50_A5URN4 Cluster: Beta-lactamase domain protein; n=5; Chloroflexi (class)|Rep: Beta-lactamase domain protein - Roseiflexus sp. RS-1 Length = 561 Score = 40.7 bits (91), Expect = 0.029 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 8/86 (9%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCG--WDEK----FDMVF--IKELKRHVNSIDAVLIS 350 L GAGE +VL+ ++ +LDCG + E D+V I L+ + I A++++ Sbjct: 11 LGGAGEVGRNMWVLEQNDEILVLDCGVMFPEADMLGVDLVLPDITYLRDQKDKIKAIVLT 70 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428 H H+GA+PY V +L PIY T Sbjct: 71 HGHEDHIGAVPYLVPELDFP-PIYGT 95 >UniRef50_Q4AMZ9 Cluster: Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase; n=2; Chlorobium|Rep: Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase - Chlorobium phaeobacteroides BS1 Length = 462 Score = 40.3 bits (90), Expect = 0.038 Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 17/157 (10%) Frame = +3 Query: 216 TPPCYVLQIDEFKFLLDCG---WDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPY 386 T C++L+ID + LLDCG E+ + + + IDAV++SH H G +P Sbjct: 13 TGSCHILRIDGRRILLDCGLVQGREEEEALNREPFPFDPREIDAVVLSHGHIDHSGRVPL 72 Query: 387 AVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD--------------LFTLDDV 524 V K G P+Y + + + D + ++ ++ L+T++DV Sbjct: 73 LV-KKGFDGPVYTHPATRDLALVLLQDSARLNERDVRYENRLRERKNMPLIEPLYTVEDV 131 Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + + LKY E+ G+ I AGH LG Sbjct: 132 VRTVNLMQGLKYGVKKEILP---GVTIRFQDAGHILG 165 >UniRef50_A5N0B8 Cluster: Putative uncharacterized protein; n=1; Clostridium kluyveri DSM 555|Rep: Putative uncharacterized protein - Clostridium kluyveri DSM 555 Length = 280 Score = 40.3 bits (90), Expect = 0.038 Identities = 38/128 (29%), Positives = 64/128 (50%), Gaps = 2/128 (1%) Frame = +3 Query: 258 LLDCGWDEKFDMVF--IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATL 431 L+D G + ++ +F IKE R ++ I+ V++SHS P H+G+ K C + A Sbjct: 40 LIDTGVKDSYEKIFSYIKEQGRSIDEINLVILSHSHPDHIGSANKI--KTITGCKVMA-- 95 Query: 432 PVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITP 611 +K Q ++ DL +K+ + L + + D +V K Q I++ + L L+I Sbjct: 96 --HKGEQEWIEDLSVQYKSRMVPGFYELVNKSVKVDELV--KDKQEIKL-DEDLTLQIIH 150 Query: 612 LPAGHSLG 635 P GHS G Sbjct: 151 SP-GHSKG 157 >UniRef50_Q11BH9 Cluster: Beta-lactamase-like; n=6; Proteobacteria|Rep: Beta-lactamase-like - Mesorhizobium sp. (strain BNC1) Length = 452 Score = 39.9 bits (89), Expect = 0.050 Identities = 44/171 (25%), Positives = 79/171 (46%), Gaps = 18/171 (10%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV-----NSIDAV 341 ++ L L GAG T ++L + + L+DCG + + ++EL +SIDAV Sbjct: 1 MLTLTSLGGAGTVTGSKHLLTNGDRRILIDCGLFQ--GLKNLRELNWEPLPVAPSSIDAV 58 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL---------YQAHKNVS 494 +++H+ H G LP V + G IYAT + ++ + D Y K S Sbjct: 59 VLTHAHLDHSGYLPKLV-RDGFKGRIYATAATRDVAELILKDSGFLNEKDAEYANRKGFS 117 Query: 495 E----FDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + L+ + D + A + + +++++++ G G +T AGH LG Sbjct: 118 KHKPALPLYGVRDAERAMEFFSIVPFDKAVQLPG---GATLTFRHAGHILG 165 >UniRef50_Q011B3 Cluster: Putative metallo beta subunit lactamase; n=1; Ostreococcus tauri|Rep: Putative metallo beta subunit lactamase - Ostreococcus tauri Length = 404 Score = 39.9 bits (89), Expect = 0.050 Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Frame = +3 Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKM--GQMFMYDLYQAH 482 L R + I+AVLI+H H+GALP+ + L + PIYA L ++ +M Y L+ Sbjct: 44 LHRWRDKIEAVLITHGHEDHIGALPWVIPALDPATPIYAGLFTMQLIKRRMLEYSLW--- 100 Query: 483 KNVSEFDLFTLDD 521 N F +F +++ Sbjct: 101 -NDDRFKVFNMNE 112 >UniRef50_Q5WCW7 Cluster: Beta-lactamase superfamily Zn-dependent hydrolase; n=1; Bacillus clausii KSM-K16|Rep: Beta-lactamase superfamily Zn-dependent hydrolase - Bacillus clausii (strain KSM-K16) Length = 367 Score = 39.5 bits (88), Expect = 0.066 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFK--FLLDCGWDEKFDMVFIKELKRHVNSIDAVLIS 350 ++K+ L G GE C++L+ + LLDCG F ++ ++ID V +S Sbjct: 1 MVKVTALGGVGEYGRNCFLLKEEATNQTILLDCGVKNGKPEQFPAITEQLASTIDVVFLS 60 Query: 351 HSDPLHLGALPYAVGK 398 H H+GALP K Sbjct: 61 HVHNDHVGALPLLAAK 76 >UniRef50_Q3LWF4 Cluster: Ysh1 3' mRNA end processing factor; n=1; Bigelowiella natans|Rep: Ysh1 3' mRNA end processing factor - Bigelowiella natans (Pedinomonas minutissima) (Chlorarachnion sp.(strain CCMP 621)) Length = 544 Score = 39.5 bits (88), Expect = 0.066 Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 13/167 (7%) Frame = +3 Query: 174 SIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-------WDEKFDMVFIKELKRHVNSI 332 SI+K+ L G + C + I F+LD G W + F+K++ + +N Sbjct: 5 SIVKILQLGGTFQIGNSCIYVMIKNTIFILDIGIIRSDKYWMHLESINFLKKITKPLN-- 62 Query: 333 DAVLISHSDPLHLGALP----YAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500 LISH H+G+LP Y K+ + Y +F Y+ + + Sbjct: 63 --FLISHYHLDHIGSLPLILNYGSDKVFFLLK-NLSYSTYLTKLLFFYNSKEFLNFTDKL 119 Query: 501 DL--FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + F DD++M + I+ +K N ++G + T +GHSLG Sbjct: 120 KIKSFNQDDIEMVMELIISVKENTVKMLRGNNIA---TFFNSGHSLG 163 >UniRef50_Q92EY9 Cluster: Lin0319 protein; n=39; Bacilli|Rep: Lin0319 protein - Listeria innocua Length = 276 Score = 39.1 bits (87), Expect = 0.088 Identities = 26/95 (27%), Positives = 45/95 (47%) Frame = +3 Query: 231 VLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLS 410 +++ + K L+DCG K ++ R +N +DA+LI+H H+ L K L Sbjct: 30 LVETGDQKILIDCGLSGKKMEGLFAQVGRDMNDLDAILITHEHSDHIKGLGVLARKYKL- 88 Query: 411 CPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515 PIYA +K + ++ K +FD+ T+ Sbjct: 89 -PIYANAKTWKAMDNMIGEVSSEQK--FQFDMETV 120 >UniRef50_Q2NK28 Cluster: Zn-dependent hydrolase; n=2; Candidatus Phytoplasma asteris|Rep: Zn-dependent hydrolase - Aster yellows witches'-broom phytoplasma (strain AYWB) Length = 574 Score = 39.1 bits (87), Expect = 0.088 Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 10/132 (7%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVF--------IKELKRHVNSID 335 IK L G GE YVLQI++ FLLD G ++ +L+ + I Sbjct: 16 IKFFALGGLGESGKNFYVLQINDSYFLLDAGLKYPNTNLYGIDSMIADYYKLQDIKDKIK 75 Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK-NVSEFDL-F 509 V +S + +LGALPY + + P+YA+ + M + + +Q+HK N F+L Sbjct: 76 GVFLSSAFETNLGALPYLMKDFDI--PVYAS--YFTMQVLKAH--FQSHKINYRNFNLQI 129 Query: 510 TLDDVDMAFDRI 545 D + FD + Sbjct: 130 VKSDERLIFDDV 141 >UniRef50_O87142 Cluster: WbfZ protein; n=32; Vibrionaceae|Rep: WbfZ protein - Vibrio cholerae Length = 446 Score = 39.1 bits (87), Expect = 0.088 Identities = 23/89 (25%), Positives = 44/89 (49%) Frame = +3 Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380 G T C+ L+ D L+DCG + D + ++ + +DA++++H+ H+G L Sbjct: 16 GKASVTGSCHELRADGQALLIDCGLFQGADERPLA-VEFALGHVDALILTHAHIDHIGRL 74 Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 P+ + G PIY T ++ + + D Sbjct: 75 PWLLA-AGFKQPIYCTAATAELVPLMLED 102 >UniRef50_A7CRQ7 Cluster: Beta-lactamase domain protein; n=1; Opitutaceae bacterium TAV2|Rep: Beta-lactamase domain protein - Opitutaceae bacterium TAV2 Length = 452 Score = 39.1 bits (87), Expect = 0.088 Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 7/159 (4%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKF-DMVFIKELKRHVN-SIDAVLISH 353 +KL L+ G C +LQI + ++D G K + + + N ID +L++H Sbjct: 1 MKLTDLNRQGGIGANCTLLQIGDINLVIDSGLHPKIAGRQAVPDFAKLRNLEIDLILVTH 60 Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMF-----MYDLYQAHKNVSEFDLFTLD 518 H+G+LP + + + +T + +M + + N+ E+ LFT + Sbjct: 61 CHLDHIGSLPVLMREHPRPPVMMSTASQMLVERMLHNSANVMKRQKEEDNIPEYPLFTHE 120 Query: 519 DVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 D+D R + + + + + IT AGH G Sbjct: 121 DIDRLAPRFTGIPFGHPKKFRPHKDEIEITLHHAGHVAG 159 >UniRef50_A0UZ06 Cluster: Beta-lactamase-like; n=1; Clostridium cellulolyticum H10|Rep: Beta-lactamase-like - Clostridium cellulolyticum H10 Length = 396 Score = 39.1 bits (87), Expect = 0.088 Identities = 22/69 (31%), Positives = 43/69 (62%), Gaps = 2/69 (2%) Frame = +3 Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISHSDPLHLGALPYAVGKL 401 Y+++ D+ L+D WD + F+++L + + ++IDA++I+H +P H G+L + K+ Sbjct: 37 YIIR-DKKTVLIDTVWDP-YKEQFVEDLDKSIGLSNIDAIVINHMEPDHGGSLGLLMSKI 94 Query: 402 GLSCPIYAT 428 + PIY T Sbjct: 95 P-NTPIYCT 102 >UniRef50_Q8IB25 Cluster: Putative uncharacterized protein MAL8P1.64; n=3; Plasmodium|Rep: Putative uncharacterized protein MAL8P1.64 - Plasmodium falciparum (isolate 3D7) Length = 1313 Score = 39.1 bits (87), Expect = 0.088 Identities = 16/42 (38%), Positives = 28/42 (66%) Frame = +3 Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP 383 L++CGWD+KF + IK + R ID ++I++ ++G+LP Sbjct: 93 LMNCGWDDKFCLEDIKNVIRVCEVIDLIIITNHSLNYIGSLP 134 >UniRef50_A6E886 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Pedobacter sp. BAL39|Rep: Metallo-beta-lactamase superfamily protein - Pedobacter sp. BAL39 Length = 460 Score = 38.7 bits (86), Expect = 0.12 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 4/100 (4%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV----NSIDAVLI 347 +KL A + T ++LQ+ ++ L+DCG D ++ +E ++ +D V++ Sbjct: 1 MKLTIWGAARQVTGSMHLLQLKDYNILIDCGLD--YEKETYQEENQYFPFDPADLDVVIL 58 Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 +H+ H G LP V ++G I T P + ++ + D Sbjct: 59 THAHIDHSGNLPTLV-RMGFQGQILCTPPTADLSELLLLD 97 >UniRef50_Q5ZWR4 Cluster: Metallo-beta lactamase family; n=4; Legionella pneumophila|Rep: Metallo-beta lactamase family - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 453 Score = 38.3 bits (85), Expect = 0.15 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLIS 350 +KL L T Y+L I K L+DCG + + + ++ L + IDAV+I+ Sbjct: 1 MKLTFLGATETVTGSKYLLTIGSKKILIDCGLFQGYKELRLRNWAPLPIDPHDIDAVIIT 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428 H+ H G LP V K G IY T Sbjct: 61 HAHIDHSGYLPLLV-KNGFQGKIYTT 85 >UniRef50_Q50EJ8 Cluster: Metallo-beta-lactamase superfamily hydrolase; n=45; Lactobacillales|Rep: Metallo-beta-lactamase superfamily hydrolase - Lactobacillus reuteri Length = 593 Score = 38.3 bits (85), Expect = 0.15 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCG--WDEK----FDMVFI--KELKRHV 323 M + IK+ G E Y ++I++ F+LD G + E D+V + L+ H Sbjct: 1 MDNNIKIIPFGGVRENGKNMYAVEIEDQIFILDTGLKYPENELMGIDVVIPDWEYLREHK 60 Query: 324 NSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503 + I V ++H +GALPY + + + P++ + + ++ + + HK V +F+ Sbjct: 61 DKIVGVFLTHGHADSIGALPYFL--MDFNVPVFGSEMTIALAKLAV----KNHKEVKKFN 114 Query: 504 LFTLDDVDMAFD 539 F + D A D Sbjct: 115 DFHVVDASTAID 126 >UniRef50_A3D3L5 Cluster: Putative uncharacterized protein; n=1; Shewanella baltica OS155|Rep: Putative uncharacterized protein - Shewanella baltica OS155 Length = 338 Score = 38.3 bits (85), Expect = 0.15 Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Frame = +3 Query: 240 IDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHL-GALP 383 + KFL+DCG F + + + +K+ +NS + ++++HSD H+ GA P Sbjct: 22 VSGIKFLVDCG----FKLTYQQHIKKKINSANFIILTHSDEDHINGAFP 66 >UniRef50_Q6MTU5 Cluster: CONSERVED HYPOTEHTICAL PROTEIN; n=3; Mollicutes|Rep: CONSERVED HYPOTEHTICAL PROTEIN - Mycoplasma mycoides subsp. mycoides SC Length = 583 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 8/89 (8%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG--WDEK----FDMVFIK--ELKRHVNSID 335 IK L G E YVL+ID F+LD G + EK D V K +K++ I Sbjct: 4 IKFTALGGQDERGKNLYVLEIDNDFFILDAGVKYPEKDILGIDTVIPKFDYIKQNKKKIK 63 Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIY 422 + +++ ++GA+PY + + + PIY Sbjct: 64 GIFLTNPSAYNMGAVPYLLKE--IKAPIY 90 >UniRef50_Q6ME06 Cluster: Putative uncharacterized protein; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein - Protochlamydia amoebophila (strain UWE25) Length = 259 Score = 37.5 bits (83), Expect = 0.27 Identities = 30/112 (26%), Positives = 50/112 (44%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356 I+K C +G + C L + K L+D G K + E+ ++ IDA+LI+H Sbjct: 2 IMKGFCPLASGSKGN-CIYLGTSQTKVLIDAGISAKAIQNRLAEINVDISDIDAILITHE 60 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFT 512 H+ L KLG+ P+ A K + +A +N +F +F+ Sbjct: 61 HSDHIQGLKVLAYKLGI--PVLANHETAK-------GIVEAFRNCPKFKIFS 103 >UniRef50_A6TSN2 Cluster: Beta-lactamase domain protein; n=1; Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase domain protein - Alkaliphilus metalliredigens QYMF Length = 245 Score = 37.5 bits (83), Expect = 0.27 Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Frame = +3 Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLG---ALPYAVGK 398 Y+L+ E K L+DCG + F + +N +DA+ ISH P H+ + YA+G Sbjct: 22 YLLEDKEIKILVDCG-NGVLSRFF--QHCHDINELDAIFISHLHPDHMSDLMVMKYAIGI 78 Query: 399 LGLSCPIYATLPVY 440 + + ++P+Y Sbjct: 79 GQMQGKVKQSIPIY 92 >UniRef50_O31760 Cluster: UPF0036 protein ymfA; n=77; Firmicutes|Rep: UPF0036 protein ymfA - Bacillus subtilis Length = 555 Score = 37.5 bits (83), Expect = 0.27 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 8/96 (8%) Frame = +3 Query: 165 KMTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEK------FDMVF--IKELKRH 320 K T +++ L G GE YV++ID F++D G D+V I L Sbjct: 4 KNTENVRIIALGGVGEIGKNLYVIEIDSDIFVVDAGLMHPENEMLGIDVVIPDISYLIER 63 Query: 321 VNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 + + A+ ++H ++G + Y + K LS P+Y T Sbjct: 64 ADRVKAIFLTHGHDENIGGVFYLLNK--LSVPVYGT 97 >UniRef50_A0YHA6 Cluster: DNA internalization-related competence protein ComEC/Rec2; n=1; marine gamma proteobacterium HTCC2143|Rep: DNA internalization-related competence protein ComEC/Rec2 - marine gamma proteobacterium HTCC2143 Length = 790 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 6/57 (10%) Frame = +3 Query: 231 VLQIDEFKFLLDCG--WDEKFDM---VFIKELKRH-VNSIDAVLISHSDPLHLGALP 383 V+Q + + D G W + FDM V I L+ H ++ ID+++ISH D H G+LP Sbjct: 530 VVQTRNYTLVYDVGARWGDDFDMAQAVLIPYLQDHGISHIDSLVISHGDNDHAGSLP 586 >UniRef50_Q8DE34 Cluster: Predicted exonuclease of the beta-lactamase fold involved in RNA processing; n=6; Vibrionales|Rep: Predicted exonuclease of the beta-lactamase fold involved in RNA processing - Vibrio vulnificus Length = 446 Score = 36.7 bits (81), Expect = 0.47 Identities = 28/126 (22%), Positives = 57/126 (45%) Frame = +3 Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380 G T C+ + L+DCG + D E+ V IDA++++H+ H+G + Sbjct: 8 GKDTVTGSCHEFRAAGIALLIDCGLFQGKD-ARPPEVDFPVKHIDALVLTHAHIDHIGRI 66 Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKY 560 P+ + G S IY T ++ + + D + ++ L + +D+ R+ +KY Sbjct: 67 PWLLA-AGFSGSIYCTEATAELVPLMLEDGLRLQLGLNHKQLHQV--LDLVKKRLKPVKY 123 Query: 561 NQSIEM 578 + + + Sbjct: 124 GEWLRL 129 >UniRef50_Q72GW5 Cluster: Cleavage and polyadenylation specificity factor, 100 kDa subunit; n=2; Thermus thermophilus|Rep: Cleavage and polyadenylation specificity factor, 100 kDa subunit - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Length = 431 Score = 36.7 bits (81), Expect = 0.47 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 1/126 (0%) Frame = +3 Query: 204 AGEETPPCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380 A E T ++L + LLDCG + K + +DAVL++H+ H+G L Sbjct: 9 AREVTGSAHLLLAGGRRVLLDCGMFQGKEEARNHAPFGFDPKEVDAVLLTHAHLDHVGRL 68 Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKY 560 P + + G P+YAT + ++ + D + V + F +DV+ A + L+Y Sbjct: 69 P-KLFREGYRGPVYATRATALLMEIVLEDALK----VMDEPFFGPEDVEEALGHLRPLEY 123 Query: 561 NQSIEM 578 + + + Sbjct: 124 GEWLRL 129 >UniRef50_A4VJP5 Cluster: Metallo-beta-lactamase superfamily protein; n=11; Gammaproteobacteria|Rep: Metallo-beta-lactamase superfamily protein - Pseudomonas stutzeri (strain A1501) Length = 505 Score = 36.7 bits (81), Expect = 0.47 Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 8/114 (7%) Frame = +3 Query: 186 LHCLSGAGEETPPCYVLQI-DEFKFLLDCGW-----DEKFD--MVFIKELKRHVNSIDAV 341 L L + T CY+++ D + LL+CG +E+ D F + K S+DAV Sbjct: 40 LSFLGAIQQVTGSCYLIETHDGARVLLECGMHQGRREEESDNRAAFAFDPK----SLDAV 95 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503 ++SH+ H G LP V LG P++ T ++ ++ + D Q + +E++ Sbjct: 96 VLSHAHIDHSGLLPRLVA-LGYRGPVHCTEATAELLELMLLDSAQIQEKDAEWE 148 >UniRef50_Q226C1 Cluster: Putative FEG protein; n=2; Tetrahymena thermophila SB210|Rep: Putative FEG protein - Tetrahymena thermophila SB210 Length = 178 Score = 36.7 bits (81), Expect = 0.47 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Frame = +3 Query: 279 EKFDMVF-IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLP 434 EK ++ I E ++ ID VLISH H+GALPY PIY T P Sbjct: 42 EKIKQIWNIPEKRKWDQIIDLVLISHFHLDHIGALPYFTEIYNYDGPIYMTSP 94 >UniRef50_A7DPN0 Cluster: Beta-lactamase domain protein; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Beta-lactamase domain protein - Candidatus Nitrosopumilus maritimus SCM1 Length = 421 Score = 36.7 bits (81), Expect = 0.47 Identities = 18/65 (27%), Positives = 37/65 (56%) Frame = +3 Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509 +DA++I+H+ H G +P + + +YAT P + + ++ + D+ + KN FDL Sbjct: 52 LDAIIITHAHLDHSGNVPSLF--VSGNTDVYATPPTFDLSKLLIEDMLKIEKNSHPFDLP 109 Query: 510 TLDDV 524 L+++ Sbjct: 110 ELNNM 114 >UniRef50_UPI000049831F Cluster: cleavage and polyadenylation specificity factor 73 kDa subunit, putative; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cleavage and polyadenylation specificity factor 73 kDa subunit, putative - Entamoeba histolytica HM-1:IMSS Length = 755 Score = 36.3 bits (80), Expect = 0.62 Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 5/150 (3%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRH--VNSIDAVLISHSDPLH 368 GAG E C++L+ +LDCG K L H ++SI+ + ++H H Sbjct: 27 GAGREVGRSCFILKYMGHNIMLDCGVHPAKPHGEAALPLFEHADIDSIELLCVTHYHVDH 86 Query: 369 LGALPYAVGKLGLSCPIYATLPVYKM-GQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRI 545 +LPY + + + T P ++ G++F + +Q + +V DRI Sbjct: 87 CASLPYLILERQFKGKVLMTPPTKEIFGELFK-EFHQMSSTIQPPKSVNPKEV---IDRI 142 Query: 546 VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 +K+++ E G++I AGH LG Sbjct: 143 DTIKFHELQEYN----GMKIWCFNAGHILG 168 >UniRef50_Q9SRR3 Cluster: F21O3.24 protein; n=3; core eudicotyledons|Rep: F21O3.24 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 620 Score = 36.3 bits (80), Expect = 0.62 Identities = 21/52 (40%), Positives = 27/52 (51%) Frame = +3 Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK 485 ID VLIS+ P+ L LP+ G IY T K+GQ+ M D+ HK Sbjct: 102 IDIVLISN--PMGLLGLPFLTQNPGFFAKIYMTEVTAKIGQLMMEDIVSMHK 151 >UniRef50_Q9FMW0 Cluster: Genomic DNA, chromosome 5, P1 clone:MLE2; n=8; Magnoliophyta|Rep: Genomic DNA, chromosome 5, P1 clone:MLE2 - Arabidopsis thaliana (Mouse-ear cress) Length = 528 Score = 36.3 bits (80), Expect = 0.62 Identities = 15/40 (37%), Positives = 27/40 (67%) Frame = +3 Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 ++R + I+AV+I+H H+GALP+ + L + PI+A+ Sbjct: 161 IRRWKHKIEAVVITHGHEDHIGALPWVIPALDPNTPIFAS 200 >UniRef50_Q9HKD3 Cluster: Putative uncharacterized protein Ta0668; n=2; Thermoplasma|Rep: Putative uncharacterized protein Ta0668 - Thermoplasma acidophilum Length = 322 Score = 36.3 bits (80), Expect = 0.62 Identities = 21/65 (32%), Positives = 34/65 (52%) Frame = +3 Query: 213 ETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAV 392 +T Y L+ D+ FL+D G + IK +++++ ID V I+H HLG + Y Sbjct: 28 KTANIYRLETDDSAFLIDSGMSDNS----IKSIEQNLKKIDFVFITHLHIDHLGGVLYLH 83 Query: 393 GKLGL 407 K G+ Sbjct: 84 EKYGI 88 >UniRef50_Q6D8S0 Cluster: Anaerobic nitric oxide reductase flavorubredoxin; n=58; root|Rep: Anaerobic nitric oxide reductase flavorubredoxin - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 509 Score = 36.3 bits (80), Expect = 0.62 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 2/65 (3%) Frame = +3 Query: 240 IDEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISHSDPLHLGALPYAVGKLGLSC 413 I E K +L D KF F++ L V N+ID ++I+H++ H GAL + ++ + Sbjct: 40 IREEKTVLIDTVDHKFSREFVQNLMAEVDLNTIDYIVINHAEEDHAGALSELMARIP-NT 98 Query: 414 PIYAT 428 PIY T Sbjct: 99 PIYCT 103 >UniRef50_Q4SGI2 Cluster: Chromosome undetermined SCAF14594, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14594, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 588 Score = 35.9 bits (79), Expect = 0.82 Identities = 14/41 (34%), Positives = 24/41 (58%) Frame = +2 Query: 320 CKFNRCCTNITLGSSTFRSSSICSWKTRS*LSNICNSTGIQ 442 C+F +C G+S SS C W+ +S ++N+ NS+ +Q Sbjct: 62 CRFKKCLMRSASGASPSGRSSACCWEMQSAMNNMMNSSQLQ 102 >UniRef50_Q89VA5 Cluster: Bll1142 protein; n=7; Bradyrhizobiaceae|Rep: Bll1142 protein - Bradyrhizobium japonicum Length = 244 Score = 35.9 bits (79), Expect = 0.82 Identities = 20/64 (31%), Positives = 31/64 (48%) Frame = +3 Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380 G+G C+ + E FL+DCG + +K L+ N ID +LI+H H L Sbjct: 13 GSGGRLNTCFHVAGREANFLIDCGASA---LPALKRLEIDRNDIDLILITHFHGDHFAGL 69 Query: 381 PYAV 392 P+ + Sbjct: 70 PFVL 73 >UniRef50_Q2G7Y1 Cluster: Beta-lactamase-like protein; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Beta-lactamase-like protein - Novosphingobium aromaticivorans (strain DSM 12444) Length = 535 Score = 35.9 bits (79), Expect = 0.82 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 3/109 (2%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDAVLIS 350 ++L+ A T C+ + + + L+DCG + + + L V+ ID V+++ Sbjct: 3 LRLNVHGAARTVTGSCFEFVLGDMRLLVDCGLFQGSRSLEALNHEPLDFDVHKIDGVIVT 62 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497 H+ H G LP + G PI+ T + ++ + D + ++ +E Sbjct: 63 HAHIDHSGLLPRLAAE-GYEGPIWCTPETAALLKVMLADAGRIQESEAE 110 >UniRef50_Q1NVJ9 Cluster: Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase; n=2; Deltaproteobacteria|Rep: Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase - delta proteobacterium MLMS-1 Length = 469 Score = 35.9 bits (79), Expect = 0.82 Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 17/169 (10%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRHVN--SIDAVLIS 350 +KL AG T ++L+++ + LLDCG + K F + N +D +++S Sbjct: 1 MKLTFHGAAGTVTGSQHLLEVNGKRILLDCGLFQGKRKEAFELNRQGFCNGKKLDCLILS 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF---------- 500 H+ H G +P V K G IY T + + + D + +F Sbjct: 61 HAHIDHSGNIPCLV-KSGFDGDIYTTQATRDLCAIMLMDSANIQEQDVQFVNKRRERNGQ 119 Query: 501 ----DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L+T +DV +A + V + + E+ G+ +T AGH LG Sbjct: 120 QPFEPLYTKEDVVLAMPQFVGIAPGRRREIYP---GIHLTLAEAGHMLG 165 >UniRef50_A6Q9T8 Cluster: RNA-metabolising metallo-beta-lactamase; n=2; Sulfurovum sp. NBC37-1|Rep: RNA-metabolising metallo-beta-lactamase - Sulfurovum sp. (strain NBC37-1) Length = 467 Score = 35.9 bits (79), Expect = 0.82 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 3/92 (3%) Frame = +3 Query: 201 GAGEE-TPPCYVLQIDE-FKFLLDCG-WDEKFDMVFIKELKRHVNSIDAVLISHSDPLHL 371 GA E T C++L+ID + L+DCG + + + S+D +L++H+ H+ Sbjct: 8 GAAEVVTGSCHLLEIDSGTRILVDCGMFQGREEHRNYGLFDFDAKSVDYLLVTHAHLDHV 67 Query: 372 GALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 G +P V K G S I AT + + ++ + D Sbjct: 68 GRIPKLV-KEGFSGTIVATDATFALAEVVLLD 98 >UniRef50_A4EC58 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 459 Score = 35.9 bits (79), Expect = 0.82 Identities = 18/42 (42%), Positives = 26/42 (61%) Frame = +3 Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP 383 L+DCG DE+ V ++ +V+ IDAV ++H D H G LP Sbjct: 238 LVDCGLDER---VVAALVRNNVHHIDAVFVTHWDEDHWGGLP 276 >UniRef50_A1ZG78 Cluster: Exonuclease of the beta-lactamase fold involved in RNA processing; n=1; Microscilla marina ATCC 23134|Rep: Exonuclease of the beta-lactamase fold involved in RNA processing - Microscilla marina ATCC 23134 Length = 476 Score = 35.9 bits (79), Expect = 0.82 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 9/105 (8%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQID-EFKFLLDCGWD---EKFDMVFIKELKRHV-----NSI 332 ++L A + T ++L++D +FK L+DCG D E+ + L + + + I Sbjct: 1 MRLTFWGAARQVTGSMHLLELDNDFKVLIDCGHDLERERKPLTDENGLYQGIFPFEPSQI 60 Query: 333 DAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 +AV+++H+ H G LP V + G IY T Y + + ++D Sbjct: 61 NAVVLTHAHIDHSGFLPNLV-REGFEGVIYCTDATYDLTNLLLHD 104 >UniRef50_A7PHF3 Cluster: Chromosome chr17 scaffold_16, whole genome shotgun sequence; n=4; Viridiplantae|Rep: Chromosome chr17 scaffold_16, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 880 Score = 35.9 bits (79), Expect = 0.82 Identities = 15/40 (37%), Positives = 26/40 (65%) Frame = +3 Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 +K+ + I+AV+I+H H+GALP+ + L PI+A+ Sbjct: 129 IKKWSHKIEAVVITHGHEDHIGALPWVIPALDSHTPIFAS 168 >UniRef50_Q4TC63 Cluster: Chromosome undetermined SCAF7053, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF7053, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 810 Score = 35.5 bits (78), Expect = 1.1 Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 7/88 (7%) Frame = +3 Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWD---EKFDMVFIKELKRHVNSIDAVLISHSDPLH 368 GAG+E C +L+ K +LDCG E D + +L ID +LISH H Sbjct: 15 GAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAE-IDLLLISHFHLDH 73 Query: 369 LGALPYAVGKL---GLSCPIYATLPVYK 443 GALP+ + K G + +AT +Y+ Sbjct: 74 CGALPWFLQKTSFKGRTFMTHATKAIYR 101 >UniRef50_Q9AA00 Cluster: Metallo-beta-lactamase family protein; n=2; Caulobacter|Rep: Metallo-beta-lactamase family protein - Caulobacter crescentus (Caulobacter vibrioides) Length = 530 Score = 35.5 bits (78), Expect = 1.1 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDA 338 MT + H AG T C L L+DCG + + + +DA Sbjct: 1 MTISLTFH--GAAGCVTGFCARLVTPRTTVLIDCGMFQGSKTLKALNYQPFPFDAGQVDA 58 Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497 VL++H+ H G LP + G PIYAT +G + + D +N E Sbjct: 59 VLLTHAHIDHSGLLPKLM-LAGFEGPIYATAATRDLGAVMLVDAGGIQENEVE 110 >UniRef50_Q5QU60 Cluster: Predicted exonuclease of the beta-lactamase fold; n=2; Alteromonadales|Rep: Predicted exonuclease of the beta-lactamase fold - Idiomarina loihiensis Length = 452 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Frame = +3 Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLISHSDPL 365 L GA T Y+++ + + L+DCG + + + + L +N +D V+++H+ Sbjct: 6 LGGAETVTGSKYLVETESTRILIDCGLFQGYKWLRRRNWQPLPMGINQVDGVVLTHAHLD 65 Query: 366 HLGALPYAVGKLGLSCPIYA 425 H G +P + K G P++A Sbjct: 66 HSGFVP-VLYKEGFRGPVFA 84 >UniRef50_Q3ADT3 Cluster: Anaerobic nitric oxide reductase flavorubredoxin; n=6; Clostridiales|Rep: Anaerobic nitric oxide reductase flavorubredoxin - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 396 Score = 35.5 bits (78), Expect = 1.1 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Frame = +3 Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISHSDPLHLGALP 383 DE L+D W KFD ++K+L + N ID V+ H + H GALP Sbjct: 42 DEKVALIDTAWI-KFDKEYVKKLSEEIDLNKIDYVVALHGEIDHSGALP 89 >UniRef50_Q1B028 Cluster: Beta-lactamase-like protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Beta-lactamase-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 813 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/94 (27%), Positives = 39/94 (41%) Frame = +3 Query: 165 KMTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVL 344 K + L GAGE ++L + L+D G + + + +D + Sbjct: 387 KSRPTLAFRALGGAGEVGGSSHLLDFGSTRVLVDAGIKPDGRGQLAPDFEE-IGPLDGAI 445 Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKM 446 I+H+ H GALP V K PIY T P K+ Sbjct: 446 ITHAHLDHCGALPLLV-KNHPQLPIYCTPPSAKL 478 >UniRef50_Q194D1 Cluster: Beta-lactamase-like; n=3; Clostridia|Rep: Beta-lactamase-like - Desulfitobacterium hafniense (strain DCB-2) Length = 570 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG---WDEKFDMVFIKELKRHVNSIDAVLIS 350 +KL+ A T Y+++ + ++ L+DCG + + + + ++AV+++ Sbjct: 1 MKLYFYGAAQVVTGSSYLVESEGYRVLIDCGLFQGSKALKELNYGDFPYNPAELNAVILT 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 H+ H G +P + K G IYAT K+ + + D Sbjct: 61 HAHTDHSGLIPKLI-KYGFQGKIYATPETIKLCSVMLPD 98 >UniRef50_Q12E81 Cluster: Beta-lactamase-like; n=14; Proteobacteria|Rep: Beta-lactamase-like - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 453 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/110 (22%), Positives = 52/110 (47%), Gaps = 3/110 (2%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLIS 350 ++L L T Y++Q D+ + L+DCG + + + ++ L +IDAV+++ Sbjct: 1 MRLQFLGATDTVTGSKYLVQHDKARVLVDCGLFQGYKQLRLRNWSPLPVKPAAIDAVVLT 60 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500 H+ H G LP + + G +Y T + ++ + D + +E+ Sbjct: 61 HAHIDHSGYLP-LLARQGFRGKVYCTPATADLCRILLPDSGHLQEEEAEY 109 >UniRef50_A6Q3H4 Cluster: RNA-metabolising metallo-beta-lactamase; n=8; Proteobacteria|Rep: RNA-metabolising metallo-beta-lactamase - Nitratiruptor sp. (strain SB155-2) Length = 462 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 3/104 (2%) Frame = +3 Query: 201 GAGEE-TPPCYVLQIDE-FKFLLDCGWDEKFD-MVFIKELKRHVNSIDAVLISHSDPLHL 371 GA E T C+ ++ D+ K L+DCG + D + L + ID +L++H H+ Sbjct: 8 GAAEVVTGSCHFVKFDDGTKALIDCGMFQGLDEWKNYEPLGFNAKEIDYLLVTHGHLDHV 67 Query: 372 GALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503 G +P + K G I AT +++ ++ + D AH +F+ Sbjct: 68 GRIP-LLYKEGFRGKIIATAATFELMKIVLLD--TAHLMQEDFE 108 >UniRef50_A1S0I1 Cluster: Beta-lactamase domain protein; n=1; Thermofilum pendens Hrk 5|Rep: Beta-lactamase domain protein - Thermofilum pendens (strain Hrk 5) Length = 441 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/102 (28%), Positives = 51/102 (50%) Frame = +3 Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509 ++AV +SH HL A+P A+ + G + PIY + P ++G Y ++ LF Sbjct: 55 VEAVFVSHLHEDHLAAVP-ALVRRGFNGPIYMSAPTAELGIKQWYKWTVLEEDGK--PLF 111 Query: 510 TLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 T +D D A ++V+ + S+ G + + +GH+LG Sbjct: 112 TEEDCDEA-RKMVKTVGDGSVVTSG---DVEVAFHQSGHALG 149 >UniRef50_A4STH4 Cluster: Anaerobic nitric oxide reductase flavorubredoxin; n=3; Gammaproteobacteria|Rep: Anaerobic nitric oxide reductase flavorubredoxin - Aeromonas salmonicida (strain A449) Length = 521 Score = 35.1 bits (77), Expect = 1.4 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 2/53 (3%) Frame = +3 Query: 276 DEKFDMVFIKELKRHVN--SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 D KF F++ L ++ SID ++I+H++ H GAL + ++ PIY T Sbjct: 52 DHKFSREFVQNLAAEIDLASIDVIVINHAEEDHAGALTELMARIP-GTPIYCT 103 >UniRef50_Q31DU4 Cluster: Phosphonate metabolism accessory protein precursor; n=2; Gammaproteobacteria|Rep: Phosphonate metabolism accessory protein precursor - Thiomicrospira crunogena (strain XCL-2) Length = 255 Score = 34.7 bits (76), Expect = 1.9 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHL-GALPYAVGKL 401 C VL+++ +FL+D G+ + ++E K S+DAVL++H H+ G P G + Sbjct: 43 CGVLEVNGVRFLIDAGY------LGLEE-KFPPGSLDAVLLTHFHMDHVQGLFPIRWG-M 94 Query: 402 GLSCPIYATLPVYKMGQMFMY-DLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQS--I 572 G S P+++ + +F Y ++ K F+ F + + +V K + Sbjct: 95 GESIPVFSPDDPHGCDDLFKYPGIFDFSKKSLPFEPFHFKGIKITPVPLVHSKLTMGYIV 154 Query: 573 EMKGKGL 593 E GK L Sbjct: 155 EFNGKRL 161 >UniRef50_Q1PVS7 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 468 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN----SIDAVL 344 +I+L + A T ++++ LLDCG + E R+ + +DA++ Sbjct: 1 MIELEFIGAAKTVTGSKHLIRTSRASVLLDCGLFQGHRKE-ADEKNRNFSIDGKQLDAIV 59 Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYAT 428 +SH+ H GALP + K G PIYAT Sbjct: 60 LSHAHIDHSGALP-CIFKNGYRGPIYAT 86 >UniRef50_Q4UBM2 Cluster: Cleavage and polyadenylation specificty factor, subunit, putative; n=4; Piroplasmida|Rep: Cleavage and polyadenylation specificty factor, subunit, putative - Theileria annulata Length = 1282 Score = 34.7 bits (76), Expect = 1.9 Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 18/174 (10%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN--SIDAV 341 M +++ L E C ++ D + DCG V + V+ ++ Sbjct: 1 MDDRVRITVLGAGCEVGRSCVYVERDNSCLMFDCGLHPALSGVGALPVFEAVDISKVEVC 60 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAH-----KNVSEFD- 503 L++H H GA+PY + K + I T + + D + K + + D Sbjct: 61 LVTHFHLDHCGAVPYLLSKTKFNGRILMTPATKSICHLLWTDYARMEQLLTVKTIFDDDD 120 Query: 504 ----------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 L++ +DV+ A DRI + ++Q I + ++I+ AGH LG Sbjct: 121 GMDELVCGSGLYSFEDVEYALDRIETIDFHQEITVN----DIKISCYRAGHVLG 170 >UniRef50_Q8RAH0 Cluster: Predicted hydrolase of the metallo-beta-lactamase superfamily; n=9; Bacteria|Rep: Predicted hydrolase of the metallo-beta-lactamase superfamily - Thermoanaerobacter tengcongensis Length = 554 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 8/91 (8%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW----DEKF--DMVF--IKELKRHVNSID 335 +K+ L G E V + ++DCG DE D+V I L ++ + Sbjct: 7 LKIIPLGGLNEIGKNMTVFEYGNDIIVVDCGLAFPDDEMLGIDLVIPDITYLLKNREKVK 66 Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 A++++H H+GALPY + +L + PIY T Sbjct: 67 AIVLTHGHEDHIGALPYVLKQLNV--PIYGT 95 >UniRef50_Q41CQ7 Cluster: Beta-lactamase-like; n=1; Exiguobacterium sibiricum 255-15|Rep: Beta-lactamase-like - Exiguobacterium sibiricum 255-15 Length = 328 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWD-EKFDMVF---IKELKRHVNSIDAVLISHSDPLHLGALPYAV 392 CYVL+ D L+DCG D E+ ++++ V+ +D V+++H H G L Y Sbjct: 23 CYVLRTDSENILIDCGPDTEQAWQAMQDGLQKIGLTVSMLDKVIVTHHHADHAG-LAYRF 81 Query: 393 GKLGLSCPIYATL-PVYKMGQMFM 461 + G+ +A L P + Q F+ Sbjct: 82 SEQGIPIYGHARLRPYLEQDQAFL 105 >UniRef50_Q97DE0 Cluster: Metallo-beta-lactamase superfamily hydrolase; n=11; Clostridia|Rep: Metallo-beta-lactamase superfamily hydrolase - Clostridium acetobutylicum Length = 261 Score = 33.9 bits (74), Expect = 3.3 Identities = 20/67 (29%), Positives = 30/67 (44%) Frame = +3 Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIY 422 D K L+D G K +KE+K N ID + ++H H+ + K + PIY Sbjct: 20 DNSKVLIDAGLSGKTIEKALKEIKEDPNEIDGIFVTHEHSDHIKGVGVLSRKYNI--PIY 77 Query: 423 ATLPVYK 443 A +K Sbjct: 78 ANELTWK 84 >UniRef50_Q5NLC0 Cluster: Metallo-beta-lactamase hydrolase subunit; n=8; Sphingomonadales|Rep: Metallo-beta-lactamase hydrolase subunit - Zymomonas mobilis Length = 546 Score = 33.9 bits (74), Expect = 3.3 Identities = 18/47 (38%), Positives = 27/47 (57%) Frame = +3 Query: 288 DMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 D+ FI+E + ++I+H H+GA+PY LG+ PIYAT Sbjct: 55 DIEFIEE---RAKDLLGIVITHGHEDHIGAIPYLAADLGV--PIYAT 96 >UniRef50_Q83XN5 Cluster: Putative beta-lactamase; n=1; Streptomyces cattleya|Rep: Putative beta-lactamase - Streptomyces cattleya Length = 329 Score = 33.9 bits (74), Expect = 3.3 Identities = 15/38 (39%), Positives = 23/38 (60%) Frame = +3 Query: 315 RHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 RH+ + D +L++H H+G LPY + K S P+ AT Sbjct: 110 RHLRAADLILLTHGHYDHIGDLPYVMRKFP-SAPVVAT 146 >UniRef50_Q3Y227 Cluster: Beta-lactamase-like; n=1; Enterococcus faecium DO|Rep: Beta-lactamase-like - Enterococcus faecium DO Length = 274 Score = 33.9 bits (74), Expect = 3.3 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 5/76 (6%) Frame = +3 Query: 252 KFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIY--- 422 K+L D G ++K + ++ +N ++AV+ISH H G L Y K G + PIY Sbjct: 32 KYLFDAGANKKL-VYNATKMGETLNDLEAVIISHGHSDHTGGLRYL--KSG-NAPIYTAE 87 Query: 423 -ATLPVY-KMGQMFMY 464 TLP Y K+ F+Y Sbjct: 88 GVTLPHYLKILTTFLY 103 >UniRef50_Q024Z8 Cluster: Beta-lactamase domain protein precursor; n=1; Solibacter usitatus Ellin6076|Rep: Beta-lactamase domain protein precursor - Solibacter usitatus (strain Ellin6076) Length = 269 Score = 33.9 bits (74), Expect = 3.3 Identities = 22/86 (25%), Positives = 39/86 (45%) Frame = +3 Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLIS 350 T+I+K C+ +G +L + + L+D G + + + + SIDA++++ Sbjct: 9 TNIVKF-CVLASGSSGNAA-LLATENTRILVDAGLSMRELRKRLALIGETLESIDAIIVT 66 Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428 H H+ LP GL IY T Sbjct: 67 HEHSDHVSGLPVLARAKGLRAVIYMT 92 >UniRef50_A6PE29 Cluster: Beta-lactamase domain protein; n=1; Shewanella sediminis HAW-EB3|Rep: Beta-lactamase domain protein - Shewanella sediminis HAW-EB3 Length = 526 Score = 33.9 bits (74), Expect = 3.3 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 6/90 (6%) Frame = +3 Query: 216 TPPCYVLQIDE-FKFLLDCGWDEKFDMVFIKELKR-----HVNSIDAVLISHSDPLHLGA 377 T C+ L I+E L+DCG + + ++ + SI A+L++H H+G Sbjct: 19 TGSCHQLVINEKSSLLIDCGLFQGAETAGSSNAEQLKIAFDIGSITALLVTHCHIDHVGR 78 Query: 378 LPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 +PY + G PI+AT + M + D Sbjct: 79 IPYLLA-AGFDQPIFATTATAALLPMVIED 107 >UniRef50_Q7QUX2 Cluster: GLP_577_37199_34023; n=1; Giardia lamblia ATCC 50803|Rep: GLP_577_37199_34023 - Giardia lamblia ATCC 50803 Length = 1058 Score = 33.9 bits (74), Expect = 3.3 Identities = 15/57 (26%), Positives = 33/57 (57%) Frame = +3 Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398 Y+L I++ L+DCG ++ +++ H+++I A+L++ + H GA Y + + Sbjct: 19 YLLTINDTLLLVDCGLAAPYE-TYLRVYDDHIDNISAILLTSAALEHAGACLYILSR 74 >UniRef50_Q6BHT7 Cluster: Similar to CA2422|IPF14997 Candida albicans IPF14997 unknown function; n=1; Debaryomyces hansenii|Rep: Similar to CA2422|IPF14997 Candida albicans IPF14997 unknown function - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 228 Score = 33.9 bits (74), Expect = 3.3 Identities = 18/54 (33%), Positives = 29/54 (53%) Frame = +3 Query: 402 GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYN 563 GLS I L YK+GQ + + +N+S+ +F +DM D I+ +K+N Sbjct: 87 GLSIQIDKLLTEYKLGQAIEHYIEITGENISKDLIFEKICIDMVDDSIIDIKFN 140 >UniRef50_A2SUA2 Cluster: Beta-lactamase domain protein; n=1; Methanocorpusculum labreanum Z|Rep: Beta-lactamase domain protein - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 271 Score = 33.9 bits (74), Expect = 3.3 Identities = 18/62 (29%), Positives = 33/62 (53%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404 C+ ++ K LLD G+ + F + K+L ++++ V+ISH H G LP+ + + Sbjct: 28 CFYIEDGTEKILLDTGYSDLF-IRNAKKLGTDLSALTKVVISHGHDDHTGGLPHLLERFD 86 Query: 405 LS 410 S Sbjct: 87 TS 88 >UniRef50_P54122 Cluster: UPF0036 protein Cgl1970/cg2160; n=31; Actinobacteria (class)|Rep: UPF0036 protein Cgl1970/cg2160 - Corynebacterium glutamicum (Brevibacterium flavum) Length = 718 Score = 33.9 bits (74), Expect = 3.3 Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 8/91 (8%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG------WDEKFDMVF--IKELKRHVNSID 335 ++++ L G E V + + ++DCG + D++ ++ H++ +D Sbjct: 155 LRIYALGGISEIGRNMTVFEYNNRLLIVDCGVLFPSSGEPGVDLILPDFGPIEDHLHRVD 214 Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 A++++H H+GA+P+ + KL PI A+ Sbjct: 215 ALVVTHGHEDHIGAIPWLL-KLRNDIPILAS 244 >UniRef50_Q9NV88 Cluster: Integrator complex subunit 9; n=41; Eumetazoa|Rep: Integrator complex subunit 9 - Homo sapiens (Human) Length = 658 Score = 33.9 bits (74), Expect = 3.3 Identities = 17/41 (41%), Positives = 23/41 (56%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFI 302 +KL+CLSG T PC VL+ +LDCG D + F+ Sbjct: 1 MKLYCLSG--HPTLPCNVLKFKSTTIMLDCGLDMTSTLNFL 39 Score = 32.7 bits (71), Expect = 7.6 Identities = 16/50 (32%), Positives = 30/50 (60%) Frame = +3 Query: 321 VNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL 470 ++++D +LIS+ + ALPY G + +YAT P ++G++ M +L Sbjct: 93 LSTVDVILISNYHCMM--ALPYITEHTGFTGTVYATEPTVQIGRLLMEEL 140 >UniRef50_Q9K9I5 Cluster: BH2662 protein; n=43; Bacteria|Rep: BH2662 protein - Bacillus halodurans Length = 555 Score = 33.5 bits (73), Expect = 4.4 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 8/87 (9%) Frame = +3 Query: 186 LHCLSGAGEETPPCYVLQIDEFKFLLDCGW----DEKFDMVFI----KELKRHVNSIDAV 341 ++ L G GE Y +Q + L+D G DE + ++ L ++ N I + Sbjct: 11 VYALGGLGEIGKNTYAVQFQDEIILIDAGIKFPEDELLGIDYVIPDYSYLVKNENKIKGL 70 Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIY 422 I+H H+G +PY + ++ + PIY Sbjct: 71 FITHGHEDHIGGIPYLLREVNI--PIY 95 >UniRef50_Q97D03 Cluster: Metallo-beta-lactamase superfamily hydrolase; n=1; Clostridium acetobutylicum|Rep: Metallo-beta-lactamase superfamily hydrolase - Clostridium acetobutylicum Length = 245 Score = 33.5 bits (73), Expect = 4.4 Identities = 19/55 (34%), Positives = 35/55 (63%), Gaps = 4/55 (7%) Frame = +3 Query: 228 YVLQIDEFKF-LLDCGWDEKFDMVFIKELKRH---VNSIDAVLISHSDPLHLGAL 380 Y+L+I+E ++ L+D G+ E + + F+K LK + +N I V+++H H+G L Sbjct: 14 YLLRINENRYVLIDTGYKEDWKL-FLKRLKENGIKINEISYVILTHHHDDHVGFL 67 >UniRef50_Q81QL9 Cluster: Hydrolase, putative; n=10; Firmicutes|Rep: Hydrolase, putative - Bacillus anthracis Length = 217 Score = 33.5 bits (73), Expect = 4.4 Identities = 17/50 (34%), Positives = 31/50 (62%), Gaps = 3/50 (6%) Frame = +3 Query: 243 DEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAVLISHSDPLHLGALP 383 DE L+D G+ +F+ + + E+KR V+ + V+++H D H+G+LP Sbjct: 27 DEMAVLIDTGFPGQFEDIQV-EMKRVGVSVDKLKVVILTHQDIDHIGSLP 75 >UniRef50_Q748A2 Cluster: Metallo-beta-lactamase family protein; n=11; Proteobacteria|Rep: Metallo-beta-lactamase family protein - Geobacter sulfurreducens Length = 561 Score = 33.5 bits (73), Expect = 4.4 Identities = 15/43 (34%), Positives = 24/43 (55%) Frame = +3 Query: 300 IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 I L+ + +L++H H+GALPY + +L L P+Y T Sbjct: 62 ITYLRERAGRVRGILLTHGHEDHIGALPYVLQELSL--PLYGT 102 >UniRef50_Q1DC87 Cluster: Metallo-beta-lactamase family protein; n=2; Cystobacterineae|Rep: Metallo-beta-lactamase family protein - Myxococcus xanthus (strain DK 1622) Length = 546 Score = 33.5 bits (73), Expect = 4.4 Identities = 15/40 (37%), Positives = 25/40 (62%) Frame = +3 Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 LK++ + VL++H HLGALPY + ++ + P+Y T Sbjct: 53 LKQNAAQLKGVLLTHGHEDHLGALPYLLNEVPV--PVYGT 90 >UniRef50_A6G7H1 Cluster: Serine/threonine kinase family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Serine/threonine kinase family protein - Plesiocystis pacifica SIR-1 Length = 914 Score = 33.5 bits (73), Expect = 4.4 Identities = 22/62 (35%), Positives = 35/62 (56%) Frame = +3 Query: 441 KMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPA 620 ++GQ+F DL +AH ++E L L D+ + + Q + +QSIE K L + + LP Sbjct: 639 RLGQLFA-DLTEAHDGLAEAKL--LSDIGTVYSK--QQEQDQSIEYFTKALQIYESRLPP 693 Query: 621 GH 626 GH Sbjct: 694 GH 695 >UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2; Roseiflexus|Rep: Beta-lactamase domain protein - Roseiflexus sp. RS-1 Length = 205 Score = 33.5 bits (73), Expect = 4.4 Identities = 19/60 (31%), Positives = 31/60 (51%) Frame = +3 Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515 A+L++H+ P H+GAL +LG+ P++A + G + D AH+ V TL Sbjct: 49 AILLTHTHPDHIGALDEMRNRLGV--PVFAHAGPHASGVVLPVDRTLAHREVITVGASTL 106 >UniRef50_A3TIY7 Cluster: Putative uncharacterized protein; n=1; Janibacter sp. HTCC2649|Rep: Putative uncharacterized protein - Janibacter sp. HTCC2649 Length = 263 Score = 33.5 bits (73), Expect = 4.4 Identities = 23/71 (32%), Positives = 34/71 (47%) Frame = +3 Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407 Y+++ + L+D GW ++ + + IDAVL+SHS P H L + L Sbjct: 37 YLVEASGQRILMDPGWATFQGLLRLADPLE----IDAVLVSHSHPDHCADLLPLLRSRAL 92 Query: 408 SCPIYATLPVY 440 S P LPVY Sbjct: 93 SEPAADPLPVY 103 >UniRef50_A5BGD5 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 665 Score = 33.5 bits (73), Expect = 4.4 Identities = 21/61 (34%), Positives = 30/61 (49%) Frame = +3 Query: 318 HVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497 +V ID VLIS P+ + LP+ G IY T ++GQ+ M DL +K + Sbjct: 115 NVPFIDVVLIS--SPMGMLGLPFLSRVNGFRAKIYVTEVTARIGQLLMEDLVLMNKEFRQ 172 Query: 498 F 500 F Sbjct: 173 F 173 >UniRef50_Q4YUZ6 Cluster: Putative uncharacterized protein; n=4; Plasmodium (Vinckeia)|Rep: Putative uncharacterized protein - Plasmodium berghei Length = 1171 Score = 33.5 bits (73), Expect = 4.4 Identities = 12/42 (28%), Positives = 25/42 (59%) Frame = +3 Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP 383 L++CGWD+ F + +K + + +D + I++ ++G LP Sbjct: 100 LINCGWDDNFCLDDVKNIIKVCEYVDIIFITNHGLSYVGCLP 141 >UniRef50_Q59M67 Cluster: Potential response regulator protein; n=2; Candida albicans|Rep: Potential response regulator protein - Candida albicans (Yeast) Length = 282 Score = 33.5 bits (73), Expect = 4.4 Identities = 16/47 (34%), Positives = 23/47 (48%) Frame = +3 Query: 219 PPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359 P C+++QI + K + D + FD +FI VN ID L D Sbjct: 178 PKCHIVQIQDSKLVKDLLHKQSFDSIFIDIEMPDVNGIDIFLFVRQD 224 >UniRef50_UPI0000E0E9AB Cluster: DNA internalization-related competence protein ComEC/Rec2; n=1; alpha proteobacterium HTCC2255|Rep: DNA internalization-related competence protein ComEC/Rec2 - alpha proteobacterium HTCC2255 Length = 745 Score = 33.1 bits (72), Expect = 5.8 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 7/85 (8%) Frame = +3 Query: 231 VLQIDEFKFLLDCGWD--EKFDMVFIKEL-----KRHVNSIDAVLISHSDPLHLGALPYA 389 +L +++ ++ D G D E F+MV L + H+N I A+ ISH D H G +P Sbjct: 498 LLLVNDSAYVFDVGNDFGESFNMVNSVLLAYVNAQPHIN-IKALYISHFDKDHAGGIPRF 556 Query: 390 VGKLGLSCPIYATLPVYKMGQMFMY 464 + L+ PIY+T + GQ ++ Sbjct: 557 ITYFPLT-PIYSTHEGCRQGQSHLW 580 >UniRef50_Q6N2A1 Cluster: Beta-lactamase-like; n=12; Rhizobiales|Rep: Beta-lactamase-like - Rhodopseudomonas palustris Length = 542 Score = 33.1 bits (72), Expect = 5.8 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Frame = +3 Query: 216 TPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV-----NSIDAVLISHSDPLHLGAL 380 T CY+ + +FL+DCG + +KEL + IDAVL++H+ H G L Sbjct: 15 TGSCYLFETKGKRFLVDCGLFQGHKT--LKELNYGAFPFRPSEIDAVLLTHAHIDHCGLL 72 Query: 381 PYAVGKLGLSCPIYAT 428 P V + G I AT Sbjct: 73 PKLV-REGFKGRILAT 87 >UniRef50_A7H6H0 Cluster: Beta-lactamase domain protein; n=2; Anaeromyxobacter|Rep: Beta-lactamase domain protein - Anaeromyxobacter sp. Fw109-5 Length = 550 Score = 33.1 bits (72), Expect = 5.8 Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 7/94 (7%) Frame = +3 Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKE----LKRHVN 326 M +++ L G GE C ++ D ++DCG +E + I L+ Sbjct: 1 MAPPVRIVPLGGLGEIGMNCMAIEADGRMAVVDCGILFPNEPIGVDVIAPDLGWLRERRE 60 Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428 + A+ ++H H+GALP+ + + + P+Y T Sbjct: 61 QVGAIYLTHGHEDHIGALPFLLRE--VKAPVYGT 92 >UniRef50_A6LMC9 Cluster: Beta-lactamase domain protein; n=1; Thermosipho melanesiensis BI429|Rep: Beta-lactamase domain protein - Thermosipho melanesiensis BI429 Length = 247 Score = 33.1 bits (72), Expect = 5.8 Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 4/74 (5%) Frame = +3 Query: 252 KFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIY--- 422 + L D G + F + K++K + I +++SH H+G L Y +GK ++ P+Y Sbjct: 28 EILFDTGASDVF-IKNAKKMKVDLRGIKKIVVSHGHYDHVGGLKYLIGK--VNAPVYIHK 84 Query: 423 -ATLPVYKMGQMFM 461 A +P Y G F+ Sbjct: 85 NAVIPKYS-GDRFV 97 >UniRef50_A5K7P0 Cluster: RNA-metabolising metallo-beta-lactamase domain containing protein; n=1; Plasmodium vivax|Rep: RNA-metabolising metallo-beta-lactamase domain containing protein - Plasmodium vivax Length = 911 Score = 33.1 bits (72), Expect = 5.8 Identities = 19/56 (33%), Positives = 26/56 (46%) Frame = +3 Query: 300 IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467 I LKR ID V+ISH H+GALP+ L I + P + + + D Sbjct: 100 INNLKRINEMIDCVIISHFHMDHIGALPFFTEILKYRGTILMSYPTKALSPILLLD 155 >UniRef50_A5K5Q9 Cluster: Putative uncharacterized protein; n=1; Plasmodium vivax|Rep: Putative uncharacterized protein - Plasmodium vivax Length = 1308 Score = 33.1 bits (72), Expect = 5.8 Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 7/110 (6%) Frame = +3 Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP---YAVGKLGLSCPIYAT 428 L++CGWD++F +K + R +D +LI++ +G P + K G PI Sbjct: 110 LINCGWDDQFRTEDVKNVLRVCEYVDLLLITNHGLNFVGCAPLLFQELQKRGRKIPIICH 169 Query: 429 LPVYKMGQMFMYDLYQAHKNVSEFDLFTLDD----VDMAFDRIVQLKYNQ 566 V + + ++ + + F F D+ V+ F + L++ + Sbjct: 170 EYVKSYSKYVLLSYFKCTSSCNFFKSFKDDEYVKMVNELFYNVTSLEFRE 219 >UniRef50_A0D1M0 Cluster: Chromosome undetermined scaffold_34, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_34, whole genome shotgun sequence - Paramecium tetraurelia Length = 747 Score = 33.1 bits (72), Expect = 5.8 Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 13/143 (9%) Frame = +3 Query: 246 EFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYA 425 + + +LDCG +++ + IK + VL+S + G LP + + + + Sbjct: 29 KLQIMLDCGLNQRLECNHIKHYMNKIQKSKLVLLSQPSIEYAGGLP-LISEFQIK--TLS 85 Query: 426 TLPVYKMGQMFMYD----LYQA--HKNVSEFDL-----FTLDDVDMAFDRIVQLKYNQSI 572 T P+ + G D L QA K + E D LD D A+ +I LK+ Q+ Sbjct: 86 TSPIIEFGVRNFVDQLIHLQQAFLKKEIMEEDFKQDWKRILDAADDAYRQIKPLKFGQNE 145 Query: 573 EMK-GKGL-GLRITPLPAGHSLG 635 M GL + + P+ AG +G Sbjct: 146 TMMFENGLFQVTVCPIRAGKVIG 168 >UniRef50_Q5V0H4 Cluster: MRNA 3'-end processing factor; n=4; Halobacteriaceae|Rep: MRNA 3'-end processing factor - Haloarcula marismortui (Halobacterium marismortui) Length = 411 Score = 33.1 bits (72), Expect = 5.8 Identities = 28/103 (27%), Positives = 41/103 (39%) Frame = +3 Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL 506 S DAV++SH H+G +P V PI+ T P Y++ D + H Sbjct: 43 SPDAVVVSHGHLDHVGTIPALVSG-DARPPIHWTPPTYELAMTLARDTLKLHGGTVNCP- 100 Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 FT +V R+ Q+ + G +T AGH G Sbjct: 101 FTETNV----RRVTQVSETHGYRESFEAAGYEVTFYNAGHIPG 139 >UniRef50_A0RY50 Cluster: Exonuclease of the beta-lactamase fold; n=1; Cenarchaeum symbiosum|Rep: Exonuclease of the beta-lactamase fold - Cenarchaeum symbiosum Length = 417 Score = 33.1 bits (72), Expect = 5.8 Identities = 16/59 (27%), Positives = 32/59 (54%) Frame = +3 Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL 506 +D+++I+H+ H G +P + + YAT P ++ ++ + D+ + NV FDL Sbjct: 48 VDSIIITHAHLDHSGNVPSMY--ISGNVDTYATAPTLELSKLLIEDMLKIKSNVHIFDL 104 >UniRef50_Q57626 Cluster: Uncharacterized protein MJ0162; n=6; Methanococcales|Rep: Uncharacterized protein MJ0162 - Methanococcus jannaschii Length = 421 Score = 33.1 bits (72), Expect = 5.8 Identities = 36/153 (23%), Positives = 67/153 (43%) Frame = +3 Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356 ++K H G + C ++ + + LLDCG + K ++DAV++SH+ Sbjct: 3 LLKFH--GGCQQIGMSCVEVETQKGRVLLDCGMSPDTGEI----PKVDDKAVDAVIVSHA 56 Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAF 536 H GA+P+ K IY T P + M+ ++ N+++ + +D+ A Sbjct: 57 HLDHCGAIPFYKFK-----KIYCTHPTADL----MFITWRDTLNLTK--AYKEEDIQHAM 105 Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635 + I L Y + ++ ++ AGH LG Sbjct: 106 ENIECLNYYEERQITE---NIKFKFYNAGHILG 135 >UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 207 Score = 32.7 bits (71), Expect = 7.6 Identities = 18/52 (34%), Positives = 30/52 (57%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380 CY+L+ ++D G D + + IKE H I+A+L++H+ H+GAL Sbjct: 15 CYILKKGTNGIIVDPGGDAELILSIIKE---HHLDINAILLTHAHFDHIGAL 63 >UniRef50_Q8DAV3 Cluster: Rec2-related protein; n=2; Vibrio vulnificus|Rep: Rec2-related protein - Vibrio vulnificus Length = 749 Score = 32.7 bits (71), Expect = 7.6 Identities = 14/26 (53%), Positives = 16/26 (61%) Frame = +3 Query: 309 LKRHVNSIDAVLISHSDPLHLGALPY 386 L R S+D V+ISH D H G LPY Sbjct: 541 LSRGSRSLDGVIISHQDDDHAGGLPY 566 >UniRef50_Q182G4 Cluster: Metallo beta-lactamase superfamily lipoprotein; n=2; Clostridium difficile|Rep: Metallo beta-lactamase superfamily lipoprotein - Clostridium difficile (strain 630) Length = 278 Score = 32.7 bits (71), Expect = 7.6 Identities = 20/81 (24%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Frame = +3 Query: 174 SIIKLHCLS-GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELK-RHVNSIDAVLI 347 S++ +H + G G+ ++Q K +L G DE + + I L+ + + +ID ++ Sbjct: 23 SLLSIHMIDVGQGDSI----LVQTPTNKNILIDGGDEDSENIIISYLRQKRIKTIDIIIA 78 Query: 348 SHSDPLHLGALPYAVGKLGLS 410 +H D H+G+L + K ++ Sbjct: 79 THPDSDHIGSLDNIIKKFNVN 99 >UniRef50_Q54SH0 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 712 Score = 32.7 bits (71), Expect = 7.6 Identities = 13/30 (43%), Positives = 20/30 (66%) Frame = +3 Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDC 269 +K+HCLS + + PC++L+ K LLDC Sbjct: 1 MKVHCLSQSAQS--PCFLLEYKNVKILLDC 28 Score = 32.7 bits (71), Expect = 7.6 Identities = 18/57 (31%), Positives = 31/57 (54%) Frame = +3 Query: 324 NSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVS 494 ++ID +LIS+ ++ ALP+ IYAT P ++G++ + +L Q K S Sbjct: 115 STIDMILISNYTNIY--ALPFITEYTNFQGKIYATEPTVQIGKLLLEELVQMDKQYS 169 >UniRef50_A2QCH2 Cluster: Putative uncharacterized protein; n=1; Aspergillus niger|Rep: Putative uncharacterized protein - Aspergillus niger Length = 512 Score = 32.7 bits (71), Expect = 7.6 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Frame = -2 Query: 472 YKSYMNI-CP-ILYTGRVAYIGQLRPSFPTAYGRAPKCRGSECDISTASIEFTCLLSSLM 299 ++SY+ C IL TGR A++G +RP+ T + RGS D +T +C S+++ Sbjct: 61 FRSYLGAPCSFILLTGRTAWMGAVRPNLGTTADKDGGRRGSLWDCTTDLRRISCRDSAVL 120 >UniRef50_O29680 Cluster: Putative uncharacterized protein; n=1; Archaeoglobus fulgidus|Rep: Putative uncharacterized protein - Archaeoglobus fulgidus Length = 209 Score = 32.7 bits (71), Expect = 7.6 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Frame = +3 Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN--SIDAVLISHSDPLHLGALPYAVG 395 CY+L +DE K L+D G D +F + LKR+++ +D ++++HS H A + G Sbjct: 15 CYLL-LDEKKALIDVGGDIQF---ILNALKRYIDPRELDYIILTHSHYDHAAAAGHFKG 69 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 634,667,529 Number of Sequences: 1657284 Number of extensions: 12723549 Number of successful extensions: 30104 Number of sequences better than 10.0: 209 Number of HSP's better than 10.0 without gapping: 29082 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 30000 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 47296372782 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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