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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV10h04f
         (635 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9V3D6 Cluster: Probable cleavage and polyadenylation s...   253   2e-66
UniRef50_Q9P2I0 Cluster: Cleavage and polyadenylation specificit...   246   3e-64
UniRef50_Q3UGU6 Cluster: Melanocyte cDNA, RIKEN full-length enri...   243   3e-63
UniRef50_A7RPX1 Cluster: Predicted protein; n=1; Nematostella ve...   233   3e-60
UniRef50_Q4S732 Cluster: Chromosome 14 SCAF14723, whole genome s...   221   9e-57
UniRef50_O17403 Cluster: Probable cleavage and polyadenylation s...   203   2e-51
UniRef50_Q8WPK6 Cluster: Similar to cleavage and polyadenylation...   191   1e-47
UniRef50_Q9LKF9 Cluster: Cleavage and polyadenylation specificit...   173   2e-42
UniRef50_Q55BS1 Cluster: Putative uncharacterized protein; n=1; ...   170   2e-41
UniRef50_Q01GI5 Cluster: Polyadenylation cleavage/specificity fa...   159   4e-38
UniRef50_A4RR19 Cluster: Predicted protein; n=1; Ostreococcus lu...   157   2e-37
UniRef50_A2EDT7 Cluster: Putative uncharacterized protein; n=1; ...   130   3e-29
UniRef50_UPI000049A022 Cluster: cleavage and polyadenylation spe...    85   1e-15
UniRef50_Q4PAM2 Cluster: Putative uncharacterized protein; n=1; ...    77   4e-13
UniRef50_O74740 Cluster: Cleavage factor two Cft2/polyadenylatio...    74   3e-12
UniRef50_Q2UQF0 Cluster: MRNA cleavage and polyadenylation facto...    71   2e-11
UniRef50_A2R7F5 Cluster: Contig An16c0120, complete genome. prec...    71   2e-11
UniRef50_Q5KIP3 Cluster: Cleavage and polyadenylation specificit...    71   2e-11
UniRef50_A7F0N0 Cluster: Putative uncharacterized protein; n=2; ...    71   3e-11
UniRef50_A6R733 Cluster: Putative uncharacterized protein; n=1; ...    70   4e-11
UniRef50_A5DXK9 Cluster: Putative uncharacterized protein; n=1; ...    70   4e-11
UniRef50_A3GHD1 Cluster: Predicted protein; n=3; Saccharomycetal...    66   5e-10
UniRef50_Q86A79 Cluster: Similar to Homo sapiens (Human). Cleava...    66   9e-10
UniRef50_UPI00015BD54C Cluster: UPI00015BD54C related cluster; n...    65   1e-09
UniRef50_Q8SUE4 Cluster: Putative uncharacterized protein ECU10_...    65   2e-09
UniRef50_Q6BSP2 Cluster: Similar to CA3384|IPF8362 Candida albic...    64   4e-09
UniRef50_Q0UZX3 Cluster: Putative uncharacterized protein; n=1; ...    63   6e-09
UniRef50_Q4QA79 Cluster: Cleavage and polyadenylation specificit...    62   1e-08
UniRef50_O13794 Cluster: Endoribonuclease ysh1; n=2; Ascomycota|...    62   1e-08
UniRef50_Q12102 Cluster: Protein CFT2; n=4; Saccharomyces cerevi...    60   4e-08
UniRef50_Q18IP5 Cluster: Predicted metal-dependent RNase, consis...    59   8e-08
UniRef50_Q750X1 Cluster: AGL182Cp; n=1; Eremothecium gossypii|Re...    58   2e-07
UniRef50_Q387M8 Cluster: Cleavage and polyadenylation specificit...    57   3e-07
UniRef50_Q5TA45 Cluster: Integrator complex subunit 11; n=29; Eu...    57   3e-07
UniRef50_A7APS1 Cluster: Putative uncharacterized protein; n=1; ...    56   5e-07
UniRef50_Q7S0J8 Cluster: Putative uncharacterized protein NCU068...    56   5e-07
UniRef50_Q74MJ3 Cluster: NEQ076; n=1; Nanoarchaeum equitans|Rep:...    56   7e-07
UniRef50_A3ERC5 Cluster: Putative RNA-processing exonuclease; n=...    56   9e-07
UniRef50_A4CGY6 Cluster: Putative uncharacterized protein; n=4; ...    55   1e-06
UniRef50_Q9U3K2 Cluster: Putative uncharacterized protein; n=2; ...    55   1e-06
UniRef50_Q8GUU3 Cluster: FEG protein; n=8; Magnoliophyta|Rep: FE...    55   2e-06
UniRef50_A6NEN7 Cluster: Uncharacterized protein CPSF3L; n=16; T...    54   2e-06
UniRef50_A4XI93 Cluster: Beta-lactamase domain protein; n=1; Cal...    54   3e-06
UniRef50_A4S2M5 Cluster: Predicted protein; n=4; Viridiplantae|R...    54   3e-06
UniRef50_Q5TA51 Cluster: Cleavage and polyadenylation specific f...    54   3e-06
UniRef50_Q4UDL0 Cluster: Putative uncharacterized protein; n=3; ...    54   4e-06
UniRef50_Q9YEQ9 Cluster: Putative exonuclease; n=1; Aeropyrum pe...    54   4e-06
UniRef50_Q5BEP0 Cluster: Endoribonuclease ysh1; n=15; Pezizomyco...    54   4e-06
UniRef50_Q6FW78 Cluster: Candida glabrata strain CBS138 chromoso...    53   5e-06
UniRef50_Q4Q2K1 Cluster: Cleavage and polyadenylation specificit...    53   7e-06
UniRef50_A2FCF8 Cluster: RNA-metabolising metallo-beta-lactamase...    53   7e-06
UniRef50_A0BGT5 Cluster: Chromosome undetermined scaffold_106, w...    53   7e-06
UniRef50_A1RWY8 Cluster: Beta-lactamase domain protein; n=1; The...    52   1e-05
UniRef50_A5ZRP6 Cluster: Putative uncharacterized protein; n=4; ...    52   2e-05
UniRef50_A3HWA3 Cluster: Metallo-beta-lactamase family protein; ...    51   3e-05
UniRef50_A2D958 Cluster: RNA-metabolising metallo-beta-lactamase...    51   3e-05
UniRef50_Q6CNJ8 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    51   3e-05
UniRef50_Q2LYC2 Cluster: Metallo-beta-lactamase protein; n=6; De...    50   4e-05
UniRef50_A5N1D0 Cluster: Putative uncharacterized protein; n=1; ...    50   4e-05
UniRef50_Q06224 Cluster: Endoribonuclease YSH1; n=10; Fungi/Meta...    50   4e-05
UniRef50_Q95PY8 Cluster: Putative uncharacterized protein; n=2; ...    50   5e-05
UniRef50_A7TEK7 Cluster: Putative uncharacterized protein; n=1; ...    50   5e-05
UniRef50_Q58633 Cluster: Uncharacterized protein MJ1236; n=16; E...    50   6e-05
UniRef50_Q24CH6 Cluster: Putative uncharacterized protein; n=1; ...    49   8e-05
UniRef50_A7DQ83 Cluster: Beta-lactamase domain protein; n=1; Can...    49   8e-05
UniRef50_Q5CRW9 Cluster: CPSF metallobeta-lactamase; n=2; Crypto...    49   1e-04
UniRef50_A1RTJ6 Cluster: Beta-lactamase domain protein; n=1; Pyr...    48   1e-04
UniRef50_Q5KCZ0 Cluster: Endoribonuclease YSH1; n=2; cellular or...    48   1e-04
UniRef50_UPI00015BA9DD Cluster: beta-lactamase domain protein; n...    48   2e-04
UniRef50_Q0LL72 Cluster: Beta-lactamase-like; n=3; Herpetosiphon...    48   2e-04
UniRef50_A6C193 Cluster: Exonuclease of the beta-lactamase fold ...    48   2e-04
UniRef50_Q9UKF6 Cluster: Cleavage and polyadenylation specificit...    48   2e-04
UniRef50_Q11PK2 Cluster: Metallo-beta-lactamase superfamily prot...    47   3e-04
UniRef50_Q5TA44 Cluster: Cleavage and polyadenylation specific f...    47   3e-04
UniRef50_Q8ZYD9 Cluster: MRNA 3'-end processing factor, conjectu...    47   3e-04
UniRef50_Q4PEJ3 Cluster: Endoribonuclease YSH1; n=6; Fungi/Metaz...    47   3e-04
UniRef50_Q6CAZ0 Cluster: Yarrowia lipolytica chromosome C of str...    47   4e-04
UniRef50_Q7RRQ3 Cluster: Cleavage and polyadenylation specificit...    46   6e-04
UniRef50_A6QXP5 Cluster: Putative uncharacterized protein; n=1; ...    46   6e-04
UniRef50_Q8KET4 Cluster: Metallo-beta-lactamase superfamily prot...    46   8e-04
UniRef50_Q73MR4 Cluster: Metallo-beta-lactamase family protein; ...    46   8e-04
UniRef50_Q4N0H3 Cluster: Putative uncharacterized protein; n=2; ...    46   8e-04
UniRef50_Q236M0 Cluster: RNA-metabolising metallo-beta-lactamase...    46   8e-04
UniRef50_Q8RBU2 Cluster: Predicted exonuclease of the beta-lacta...    46   0.001
UniRef50_Q23NE4 Cluster: Putative uncharacterized protein; n=1; ...    46   0.001
UniRef50_A0RXV0 Cluster: Cleavage and polyadenylation specificit...    46   0.001
UniRef50_Q1GJ92 Cluster: Beta-lactamase-like protein; n=4; Rhodo...    45   0.002
UniRef50_Q8SRZ4 Cluster: CLEAVAGE AND POLYADENYLATION SPECIFICIT...    44   0.002
UniRef50_Q6BMW3 Cluster: Endoribonuclease YSH1; n=2; Saccharomyc...    44   0.002
UniRef50_A5KD85 Cluster: Cleavage and polyadenylation specifity ...    44   0.003
UniRef50_Q3ZY44 Cluster: Metallo-beta-lactamase family protein; ...    44   0.004
UniRef50_Q2YZG4 Cluster: Predicted exonuclease of the beta-lacta...    44   0.004
UniRef50_Q7UMQ3 Cluster: Cleavage and polyadenylation specifity ...    43   0.005
UniRef50_Q15V20 Cluster: RNA-metabolising metallo-beta-lactamase...    43   0.005
UniRef50_Q8TW11 Cluster: Predicted metal-dependent RNase, consis...    43   0.005
UniRef50_A5KKJ4 Cluster: Putative uncharacterized protein; n=1; ...    43   0.007
UniRef50_A3I563 Cluster: Zn-dependent hydrolase, beta-lactamase ...    43   0.007
UniRef50_Q9UXE8 Cluster: MRNA 3'-end polyadenylation factor; n=6...    43   0.007
UniRef50_Q5CPX2 Cluster: Cleavage and polyadenylation specifity ...    42   0.009
UniRef50_Q97AZ6 Cluster: Cleavage and polyadenylation specificit...    42   0.009
UniRef50_Q9RZ85 Cluster: Cleavage and polyadenylation specificit...    42   0.012
UniRef50_Q6MLH4 Cluster: Predicted exonuclease of the beta-lacta...    42   0.012
UniRef50_A7QCN8 Cluster: Chromosome chr12 scaffold_78, whole gen...    42   0.012
UniRef50_Q7QYP3 Cluster: GLP_393_23867_26140; n=1; Giardia lambl...    42   0.012
UniRef50_A7AWH8 Cluster: RNA-metabolising metallo-beta-lactamase...    42   0.012
UniRef50_Q60355 Cluster: Uncharacterized protein MJ0047; n=6; Me...    42   0.012
UniRef50_UPI00004992E1 Cluster: cleavage and polyadenylation spe...    42   0.016
UniRef50_Q3AAG6 Cluster: Metallo-beta-lactamase family protein; ...    42   0.016
UniRef50_A3WMD7 Cluster: Predicted exonuclease of the beta-lacta...    42   0.016
UniRef50_Q0HMU8 Cluster: RNA-metabolizing metallo-beta-lactamase...    41   0.022
UniRef50_Q0EST3 Cluster: Beta-lactamase-like; n=2; Thermoanaerob...    41   0.022
UniRef50_Q023M0 Cluster: Beta-lactamase domain protein; n=1; Sol...    41   0.022
UniRef50_A7HPZ1 Cluster: Beta-lactamase domain protein; n=2; Alp...    41   0.022
UniRef50_A6FNJ5 Cluster: Beta-lactamase-like protein; n=1; Roseo...    41   0.022
UniRef50_A0JWK6 Cluster: Beta-lactamase domain protein; n=2; Bac...    41   0.022
UniRef50_Q2RJ88 Cluster: RNA-metabolising metallo-beta-lactamase...    41   0.029
UniRef50_A5URN4 Cluster: Beta-lactamase domain protein; n=5; Chl...    41   0.029
UniRef50_Q4AMZ9 Cluster: Beta-lactamase-like:RNA-metabolising me...    40   0.038
UniRef50_A5N0B8 Cluster: Putative uncharacterized protein; n=1; ...    40   0.038
UniRef50_Q11BH9 Cluster: Beta-lactamase-like; n=6; Proteobacteri...    40   0.050
UniRef50_Q011B3 Cluster: Putative metallo beta subunit lactamase...    40   0.050
UniRef50_Q5WCW7 Cluster: Beta-lactamase superfamily Zn-dependent...    40   0.066
UniRef50_Q3LWF4 Cluster: Ysh1 3' mRNA end processing factor; n=1...    40   0.066
UniRef50_Q92EY9 Cluster: Lin0319 protein; n=39; Bacilli|Rep: Lin...    39   0.088
UniRef50_Q2NK28 Cluster: Zn-dependent hydrolase; n=2; Candidatus...    39   0.088
UniRef50_O87142 Cluster: WbfZ protein; n=32; Vibrionaceae|Rep: W...    39   0.088
UniRef50_A7CRQ7 Cluster: Beta-lactamase domain protein; n=1; Opi...    39   0.088
UniRef50_A0UZ06 Cluster: Beta-lactamase-like; n=1; Clostridium c...    39   0.088
UniRef50_Q8IB25 Cluster: Putative uncharacterized protein MAL8P1...    39   0.088
UniRef50_A6E886 Cluster: Metallo-beta-lactamase superfamily prot...    39   0.12 
UniRef50_Q5ZWR4 Cluster: Metallo-beta lactamase family; n=4; Leg...    38   0.15 
UniRef50_Q50EJ8 Cluster: Metallo-beta-lactamase superfamily hydr...    38   0.15 
UniRef50_A3D3L5 Cluster: Putative uncharacterized protein; n=1; ...    38   0.15 
UniRef50_Q6MTU5 Cluster: CONSERVED HYPOTEHTICAL PROTEIN; n=3; Mo...    38   0.20 
UniRef50_Q6ME06 Cluster: Putative uncharacterized protein; n=1; ...    38   0.27 
UniRef50_A6TSN2 Cluster: Beta-lactamase domain protein; n=1; Alk...    38   0.27 
UniRef50_O31760 Cluster: UPF0036 protein ymfA; n=77; Firmicutes|...    38   0.27 
UniRef50_A0YHA6 Cluster: DNA internalization-related competence ...    37   0.35 
UniRef50_Q8DE34 Cluster: Predicted exonuclease of the beta-lacta...    37   0.47 
UniRef50_Q72GW5 Cluster: Cleavage and polyadenylation specificit...    37   0.47 
UniRef50_A4VJP5 Cluster: Metallo-beta-lactamase superfamily prot...    37   0.47 
UniRef50_Q226C1 Cluster: Putative FEG protein; n=2; Tetrahymena ...    37   0.47 
UniRef50_A7DPN0 Cluster: Beta-lactamase domain protein; n=1; Can...    37   0.47 
UniRef50_UPI000049831F Cluster: cleavage and polyadenylation spe...    36   0.62 
UniRef50_Q9SRR3 Cluster: F21O3.24 protein; n=3; core eudicotyled...    36   0.62 
UniRef50_Q9FMW0 Cluster: Genomic DNA, chromosome 5, P1 clone:MLE...    36   0.62 
UniRef50_Q9HKD3 Cluster: Putative uncharacterized protein Ta0668...    36   0.62 
UniRef50_Q6D8S0 Cluster: Anaerobic nitric oxide reductase flavor...    36   0.62 
UniRef50_Q4SGI2 Cluster: Chromosome undetermined SCAF14594, whol...    36   0.82 
UniRef50_Q89VA5 Cluster: Bll1142 protein; n=7; Bradyrhizobiaceae...    36   0.82 
UniRef50_Q2G7Y1 Cluster: Beta-lactamase-like protein; n=1; Novos...    36   0.82 
UniRef50_Q1NVJ9 Cluster: Beta-lactamase-like:RNA-metabolising me...    36   0.82 
UniRef50_A6Q9T8 Cluster: RNA-metabolising metallo-beta-lactamase...    36   0.82 
UniRef50_A4EC58 Cluster: Putative uncharacterized protein; n=1; ...    36   0.82 
UniRef50_A1ZG78 Cluster: Exonuclease of the beta-lactamase fold ...    36   0.82 
UniRef50_A7PHF3 Cluster: Chromosome chr17 scaffold_16, whole gen...    36   0.82 
UniRef50_Q4TC63 Cluster: Chromosome undetermined SCAF7053, whole...    36   1.1  
UniRef50_Q9AA00 Cluster: Metallo-beta-lactamase family protein; ...    36   1.1  
UniRef50_Q5QU60 Cluster: Predicted exonuclease of the beta-lacta...    36   1.1  
UniRef50_Q3ADT3 Cluster: Anaerobic nitric oxide reductase flavor...    36   1.1  
UniRef50_Q1B028 Cluster: Beta-lactamase-like protein; n=1; Rubro...    36   1.1  
UniRef50_Q194D1 Cluster: Beta-lactamase-like; n=3; Clostridia|Re...    36   1.1  
UniRef50_Q12E81 Cluster: Beta-lactamase-like; n=14; Proteobacter...    35   1.4  
UniRef50_A6Q3H4 Cluster: RNA-metabolising metallo-beta-lactamase...    35   1.4  
UniRef50_A1S0I1 Cluster: Beta-lactamase domain protein; n=1; The...    35   1.4  
UniRef50_A4STH4 Cluster: Anaerobic nitric oxide reductase flavor...    35   1.4  
UniRef50_Q31DU4 Cluster: Phosphonate metabolism accessory protei...    35   1.9  
UniRef50_Q1PVS7 Cluster: Putative uncharacterized protein; n=1; ...    35   1.9  
UniRef50_Q4UBM2 Cluster: Cleavage and polyadenylation specificty...    35   1.9  
UniRef50_Q8RAH0 Cluster: Predicted hydrolase of the metallo-beta...    34   2.5  
UniRef50_Q41CQ7 Cluster: Beta-lactamase-like; n=1; Exiguobacteri...    34   2.5  
UniRef50_Q97DE0 Cluster: Metallo-beta-lactamase superfamily hydr...    34   3.3  
UniRef50_Q5NLC0 Cluster: Metallo-beta-lactamase hydrolase subuni...    34   3.3  
UniRef50_Q83XN5 Cluster: Putative beta-lactamase; n=1; Streptomy...    34   3.3  
UniRef50_Q3Y227 Cluster: Beta-lactamase-like; n=1; Enterococcus ...    34   3.3  
UniRef50_Q024Z8 Cluster: Beta-lactamase domain protein precursor...    34   3.3  
UniRef50_A6PE29 Cluster: Beta-lactamase domain protein; n=1; She...    34   3.3  
UniRef50_Q7QUX2 Cluster: GLP_577_37199_34023; n=1; Giardia lambl...    34   3.3  
UniRef50_Q6BHT7 Cluster: Similar to CA2422|IPF14997 Candida albi...    34   3.3  
UniRef50_A2SUA2 Cluster: Beta-lactamase domain protein; n=1; Met...    34   3.3  
UniRef50_P54122 Cluster: UPF0036 protein Cgl1970/cg2160; n=31; A...    34   3.3  
UniRef50_Q9NV88 Cluster: Integrator complex subunit 9; n=41; Eum...    34   3.3  
UniRef50_Q9K9I5 Cluster: BH2662 protein; n=43; Bacteria|Rep: BH2...    33   4.4  
UniRef50_Q97D03 Cluster: Metallo-beta-lactamase superfamily hydr...    33   4.4  
UniRef50_Q81QL9 Cluster: Hydrolase, putative; n=10; Firmicutes|R...    33   4.4  
UniRef50_Q748A2 Cluster: Metallo-beta-lactamase family protein; ...    33   4.4  
UniRef50_Q1DC87 Cluster: Metallo-beta-lactamase family protein; ...    33   4.4  
UniRef50_A6G7H1 Cluster: Serine/threonine kinase family protein;...    33   4.4  
UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2; Ros...    33   4.4  
UniRef50_A3TIY7 Cluster: Putative uncharacterized protein; n=1; ...    33   4.4  
UniRef50_A5BGD5 Cluster: Putative uncharacterized protein; n=1; ...    33   4.4  
UniRef50_Q4YUZ6 Cluster: Putative uncharacterized protein; n=4; ...    33   4.4  
UniRef50_Q59M67 Cluster: Potential response regulator protein; n...    33   4.4  
UniRef50_UPI0000E0E9AB Cluster: DNA internalization-related comp...    33   5.8  
UniRef50_Q6N2A1 Cluster: Beta-lactamase-like; n=12; Rhizobiales|...    33   5.8  
UniRef50_A7H6H0 Cluster: Beta-lactamase domain protein; n=2; Ana...    33   5.8  
UniRef50_A6LMC9 Cluster: Beta-lactamase domain protein; n=1; The...    33   5.8  
UniRef50_A5K7P0 Cluster: RNA-metabolising metallo-beta-lactamase...    33   5.8  
UniRef50_A5K5Q9 Cluster: Putative uncharacterized protein; n=1; ...    33   5.8  
UniRef50_A0D1M0 Cluster: Chromosome undetermined scaffold_34, wh...    33   5.8  
UniRef50_Q5V0H4 Cluster: MRNA 3'-end processing factor; n=4; Hal...    33   5.8  
UniRef50_A0RY50 Cluster: Exonuclease of the beta-lactamase fold;...    33   5.8  
UniRef50_Q57626 Cluster: Uncharacterized protein MJ0162; n=6; Me...    33   5.8  
UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1; Oc...    33   7.6  
UniRef50_Q8DAV3 Cluster: Rec2-related protein; n=2; Vibrio vulni...    33   7.6  
UniRef50_Q182G4 Cluster: Metallo beta-lactamase superfamily lipo...    33   7.6  
UniRef50_Q54SH0 Cluster: Putative uncharacterized protein; n=1; ...    33   7.6  
UniRef50_A2QCH2 Cluster: Putative uncharacterized protein; n=1; ...    33   7.6  
UniRef50_O29680 Cluster: Putative uncharacterized protein; n=1; ...    33   7.6  

>UniRef50_Q9V3D6 Cluster: Probable cleavage and polyadenylation
           specificity factor subunit 2; n=7; Coelomata|Rep:
           Probable cleavage and polyadenylation specificity factor
           subunit 2 - Drosophila melanogaster (Fruit fly)
          Length = 756

 Score =  253 bits (620), Expect = 2e-66
 Identities = 110/156 (70%), Positives = 134/156 (85%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           MTSIIKLH +SGA +E+PPCY+LQID+ + LLDCGWDEKFD  FIKELKR V+++DAVL+
Sbjct: 1   MTSIIKLHTISGAMDESPPCYILQIDDVRILLDCGWDEKFDANFIKELKRQVHTLDAVLL 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH D  HLGALPY VGKLGL+CPIYAT+PV+KMGQMFMYDLY +H N+ +FDLF+LDDVD
Sbjct: 61  SHPDAYHLGALPYLVGKLGLNCPIYATIPVFKMGQMFMYDLYMSHFNMGDFDLFSLDDVD 120

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            AF++I QLKYNQ++ +K KG G+ ITPL AGH +G
Sbjct: 121 TAFEKITQLKYNQTVSLKDKGYGISITPLNAGHMIG 156


>UniRef50_Q9P2I0 Cluster: Cleavage and polyadenylation specificity
           factor subunit 2; n=26; Coelomata|Rep: Cleavage and
           polyadenylation specificity factor subunit 2 - Homo
           sapiens (Human)
          Length = 782

 Score =  246 bits (602), Expect = 3e-64
 Identities = 111/156 (71%), Positives = 129/156 (82%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           MTSIIKL  LSG  EE+  CY+LQ+DEF+FLLDCGWDE F M  I  L++HV+ IDAVL+
Sbjct: 1   MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSMDIIDSLRKHVHQIDAVLL 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH DPLHLGALPYAVGKLGL+C IYAT+PVYKMGQMFMYDLYQ+  N  +F LFTLDDVD
Sbjct: 61  SHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVD 120

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            AFD+I QLK++Q + +KGKG GL ITPLPAGH +G
Sbjct: 121 AAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIG 156


>UniRef50_Q3UGU6 Cluster: Melanocyte cDNA, RIKEN full-length
           enriched library, clone:G270022C12 product:cleavage and
           polyadenylation specific factor 2, full insert sequence;
           n=5; Eutheria|Rep: Melanocyte cDNA, RIKEN full-length
           enriched library, clone:G270022C12 product:cleavage and
           polyadenylation specific factor 2, full insert sequence
           - Mus musculus (Mouse)
          Length = 412

 Score =  243 bits (594), Expect = 3e-63
 Identities = 109/156 (69%), Positives = 129/156 (82%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           MTSIIKL  LSG  EE+  CY+LQ+DEF+FLLDCGWDE F +  I  L++HV+ IDAVL+
Sbjct: 1   MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSVDIIDSLRKHVHQIDAVLL 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH DPLHLGALP+AVGKLGL+C IYAT+PVYKMGQMFMYDLYQ+  N  +F LFTLDDVD
Sbjct: 61  SHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVD 120

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            AFD+I QLK++Q + +KGKG GL ITPLPAGH +G
Sbjct: 121 AAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIG 156


>UniRef50_A7RPX1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 737

 Score =  233 bits (570), Expect = 3e-60
 Identities = 100/156 (64%), Positives = 124/156 (79%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           MTSIIKL+ LSGA +E P CY+LQ+DEF+FLLDCGW+E  DM  ++ +KRHV  +DAVL+
Sbjct: 1   MTSIIKLNVLSGAHDEAPLCYLLQVDEFRFLLDCGWNETLDMEIMESIKRHVQQVDAVLV 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           S  D  H+G LPY VGK GL CPIY T+PVYKMGQMFMYD YQ H+N  EFD+F+LDDVD
Sbjct: 61  SFPDIYHMGGLPYLVGKCGLHCPIYTTIPVYKMGQMFMYDWYQCHQNSEEFDVFSLDDVD 120

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             FD+I+QLKY+Q++ +KGKG G+ ITP  AGH +G
Sbjct: 121 AVFDKIIQLKYSQTVSLKGKGHGITITPYAAGHMIG 156


>UniRef50_Q4S732 Cluster: Chromosome 14 SCAF14723, whole genome
           shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 14
           SCAF14723, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 765

 Score =  221 bits (541), Expect = 9e-57
 Identities = 109/180 (60%), Positives = 129/180 (71%), Gaps = 24/180 (13%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           MTSIIKL  +SG  EE+  CY+LQ+DEF+FLLDCGWDE F M  I  +KR+V+ +DAVL+
Sbjct: 1   MTSIIKLTAVSGVQEESALCYLLQVDEFRFLLDCGWDENFSMDIIDAMKRYVHQVDAVLL 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH DP+HLGALPYAVGKLGL+C IYAT+PVYKMGQMFMYDLYQ+  N  +F LFTLDDVD
Sbjct: 61  SHPDPIHLGALPYAVGKLGLNCTIYATIPVYKMGQMFMYDLYQSRNNSEDFTLFTLDDVD 120

Query: 528 MAFDRIVQLKYNQSIEMK------------------------GKGLGLRITPLPAGHSLG 635
            AFD+I QLKY+Q + +K                        GKG GL ITPLPAGH +G
Sbjct: 121 SAFDKIQQLKYSQIVSLKGKLASKRLFTWSKLPKYVMAFYATGKGHGLSITPLPAGHMIG 180


>UniRef50_O17403 Cluster: Probable cleavage and polyadenylation
           specificity factor subunit 2; n=2; Caenorhabditis|Rep:
           Probable cleavage and polyadenylation specificity factor
           subunit 2 - Caenorhabditis elegans
          Length = 843

 Score =  203 bits (496), Expect = 2e-51
 Identities = 92/156 (58%), Positives = 117/156 (75%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           MTSIIKL   SGA +E P CY+LQ+D    LLDCGWDE+F + + +ELK  +  I AVLI
Sbjct: 1   MTSIIKLKVFSGAKDEGPLCYLLQVDGDYILLDCGWDERFGLQYFEELKPFIPKISAVLI 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH DPLHLG LPY V K GL+ P+YAT+PVYKMGQMF+YD+  +H +V EF+ +TLDDVD
Sbjct: 61  SHPDPLHLGGLPYLVSKCGLTAPVYATVPVYKMGQMFIYDMVYSHLDVEEFEHYTLDDVD 120

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            AF+++ Q+KYNQ++ +KG   G+  T LPAGH LG
Sbjct: 121 TAFEKVEQVKYNQTVVLKGDS-GVHFTALPAGHMLG 155


>UniRef50_Q8WPK6 Cluster: Similar to cleavage and polyadenylation
           factor; n=1; Oikopleura dioica|Rep: Similar to cleavage
           and polyadenylation factor - Oikopleura dioica
           (Tunicate)
          Length = 765

 Score =  191 bits (465), Expect = 1e-47
 Identities = 87/156 (55%), Positives = 111/156 (71%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           MTSI+K   LSG  +E P C++LQID+FKFLLDCGW E+     I  LKRH   IDA+LI
Sbjct: 1   MTSIVKFQSLSGFDDEAPHCHLLQIDDFKFLLDCGWAEQHHEKIIDGLKRHGRQIDAILI 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH D LH G LPY + KLG++CPIY T+P  KMGQMF+YD   +   V +FD+FTLDDVD
Sbjct: 61  SHPDLLHCGMLPY-LSKLGITCPIYMTMPACKMGQMFLYDFVLSRTAVEDFDMFTLDDVD 119

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             FDR  QLK+NQ+  ++G+  G++I P+ AGH +G
Sbjct: 120 AVFDRATQLKHNQTEAVRGQDYGIQIMPVQAGHMIG 155


>UniRef50_Q9LKF9 Cluster: Cleavage and polyadenylation specificity
           factor subunit 2; n=8; Magnoliophyta|Rep: Cleavage and
           polyadenylation specificity factor subunit 2 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 739

 Score =  173 bits (422), Expect = 2e-42
 Identities = 77/156 (49%), Positives = 110/156 (70%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           M + +++  L G   E P  Y++ ID F FL+DCGW++ FD   ++ L R  ++IDAVL+
Sbjct: 1   MGTSVQVTPLCGVYNENPLSYLVSIDGFNFLIDCGWNDLFDTSLLEPLSRVASTIDAVLL 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH D LH+GALPYA+ +LGLS P+YAT PV+++G + MYD + + K VS+FDLFTLDD+D
Sbjct: 61  SHPDTLHIGALPYAMKQLGLSAPVYATEPVHRLGLLTMYDQFLSRKQVSDFDLFTLDDID 120

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            AF  +++L Y+Q+  + GKG G+ I P  AGH LG
Sbjct: 121 SAFQNVIRLTYSQNYHLSGKGEGIVIAPHVAGHMLG 156


>UniRef50_Q55BS1 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 784

 Score =  170 bits (414), Expect = 2e-41
 Identities = 79/158 (50%), Positives = 105/158 (66%), Gaps = 2/158 (1%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLI 347
           M SIIK   LSGA +E+PPCY+L+ID+F  LLDCG     D   ++ L++    IDAVL+
Sbjct: 1   MASIIKFTALSGAKDESPPCYLLEIDDFCILLDCGLSYNLDFSLLEPLEKVAKKIDAVLL 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SHSD  H+G LPY VGK GL+  IY T PV KMG MF+YDLY+   +  EF  ++LD++D
Sbjct: 61  SHSDTTHIGGLPYVVGKYGLTGTIYGTTPVLKMGTMFLYDLYENKMSQEEFQQYSLDNID 120

Query: 528 MAF--DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             F  DR  +L ++Q   + GKG G+ ITP  AGH++G
Sbjct: 121 SCFGEDRFKELSFSQHYSLSGKGKGISITPYLAGHTIG 158


>UniRef50_Q01GI5 Cluster: Polyadenylation cleavage/specificity
           factor 100 kDa subunit; n=1; Ostreococcus tauri|Rep:
           Polyadenylation cleavage/specificity factor 100 kDa
           subunit - Ostreococcus tauri
          Length = 807

 Score =  159 bits (387), Expect = 4e-38
 Identities = 75/146 (51%), Positives = 98/146 (67%), Gaps = 1/146 (0%)
 Frame = +3

Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380
           GAGE    CY + ID    LLDCGW + FD+  +K L+     +DAVLISH D  HLGAL
Sbjct: 40  GAGERAM-CYHVSIDGCNILLDCGWTDAFDVEMLKPLEAIAKDVDAVLISHPDTAHLGAL 98

Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF-DLFTLDDVDMAFDRIVQLK 557
           PYA GKLG++C +YATLPV+KMGQM+MYD +   ++  +F + F+LDDVD AF   V +K
Sbjct: 99  PYAFGKLGMNCKVYATLPVHKMGQMYMYDHFLTRQDQEDFQETFSLDDVDKAFAAFVPVK 158

Query: 558 YNQSIEMKGKGLGLRITPLPAGHSLG 635
           Y Q   ++GKG G+ +    AGH+LG
Sbjct: 159 YQQLSMLRGKGEGISVMAYAAGHTLG 184


>UniRef50_A4RR19 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 715

 Score =  157 bits (381), Expect = 2e-37
 Identities = 72/138 (52%), Positives = 96/138 (69%), Gaps = 1/138 (0%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404
           CY + ID    LLDCGW++KFD+  +K L      +DAVLISH D  HLGALPYA GKLG
Sbjct: 2   CYHVSIDGCNILLDCGWNDKFDVDMLKPLAAIAPKVDAVLISHPDTAHLGALPYAFGKLG 61

Query: 405 LSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF-DLFTLDDVDMAFDRIVQLKYNQSIEMK 581
           ++C +YATLPV+KMGQM+MYD +   ++  +F ++F+LDDVD AF   V +KY Q   ++
Sbjct: 62  MNCKVYATLPVHKMGQMYMYDHFLTRQDQGDFQEVFSLDDVDTAFAAFVPVKYMQLSMLR 121

Query: 582 GKGLGLRITPLPAGHSLG 635
           GKG G+ +    AGH+LG
Sbjct: 122 GKGDGISVMAYAAGHTLG 139


>UniRef50_A2EDT7 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 700

 Score =  130 bits (314), Expect = 3e-29
 Identities = 66/155 (42%), Positives = 95/155 (61%)
 Frame = +3

Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLIS 350
           T+ I    LSGA   TP  Y+L +DEF FLLDCGW E F +  I+      + ++AVL+S
Sbjct: 5   TTSISFQPLSGAQSTTPFAYLLHVDEFTFLLDCGWTEDFRLEDIQTQIEICSHVNAVLLS 64

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDM 530
           H+   H+GALPY     GLS PI+AT+P+  +G + +YD Y   ++  EF  F  +D+D 
Sbjct: 65  HASIEHIGALPYLCSH-GLSAPIFATMPIPALGSLLIYDSYLNIRDEEEFKEFNANDIDQ 123

Query: 531 AFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           AF +I ++ Y QS ++ GK   + ITP  AG++LG
Sbjct: 124 AFQKINRMTYQQSEQLDGK--NITITPYNAGNTLG 156


>UniRef50_UPI000049A022 Cluster: cleavage and polyadenylation
           specificity factor; n=1; Entamoeba histolytica
           HM-1:IMSS|Rep: cleavage and polyadenylation specificity
           factor - Entamoeba histolytica HM-1:IMSS
          Length = 693

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 53/152 (34%), Positives = 83/152 (54%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359
           I+   L   G+ +P   +L+I+  K LLDCG D  F    I++    ++ ID VLISHSD
Sbjct: 3   IRTRSLFDGGKTSPISALLEINSTKILLDCGVDCNFTREIIEKYDS-ISDIDIVLISHSD 61

Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFD 539
             H+GALPY   K   +C IY T PV KMG + M +  +  + +  +  + L DV+  + 
Sbjct: 62  LRHMGALPYIANK-NPNCSIYTTDPVGKMGYLCMKEAIKTQQLIG-YPCYRLKDVEQTYK 119

Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           RI  L+Y   ++  G+   + ++  P+G +LG
Sbjct: 120 RIFLLEY-YKLQKCGE---VEVSAHPSGRTLG 147


>UniRef50_Q4PAM2 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 979

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 44/120 (36%), Positives = 66/120 (55%), Gaps = 11/120 (9%)
 Frame = +3

Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKN 488
           L++  ++ID VL+SHS   HLG   YA   LGL C +YAT+PV  MG++ + +  Q  ++
Sbjct: 120 LRQLASTIDLVLLSHSSLDHLGLYAYAHANLGLRCQVYATMPVQSMGKLTVLEAIQTWRS 179

Query: 489 VSEFD-----------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             + +           L T D V+ AF+ I  ++Y Q   ++GK   L +T   AGHSLG
Sbjct: 180 EVDIEKECTSASTRRCLATPDQVEDAFEEIKTVRYMQPTHLEGKCASLTLTAYNAGHSLG 239


>UniRef50_O74740 Cluster: Cleavage factor two Cft2/polyadenylation
           factor CPSF-73; n=1; Schizosaccharomyces pombe|Rep:
           Cleavage factor two Cft2/polyadenylation factor CPSF-73
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 797

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 44/102 (43%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
 Frame = +3

Query: 333 DAVLISHSDPLHLGALPYAVGKLGL-SCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509
           D +L+SHSD  H+G L YA  K    +  IYATLP   MG+M M D  +++  +S+    
Sbjct: 45  DLILLSHSDLAHIGGLVYAYYKYDWKNAYIYATLPTINMGRMTMLDAIKSNY-ISDM--- 100

Query: 510 TLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +  DVD  FD I+ L+Y Q   + GK  GL IT   AGH+LG
Sbjct: 101 SKADVDAVFDSIIPLRYQQPTLLLGKCSGLTITAYNAGHTLG 142


>UniRef50_Q2UQF0 Cluster: MRNA cleavage and polyadenylation factor
           II complex; n=7; Eurotiomycetidae|Rep: MRNA cleavage and
           polyadenylation factor II complex - Aspergillus oryzae
          Length = 1014

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 3/93 (3%)
 Frame = +3

Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407
           +L++D   K L+D GWD+ FD + ++EL++HV ++  +L++H+ P H+GA  +      L
Sbjct: 21  ILELDGGIKILVDVGWDDTFDPLDLQELEKHVPTLSLILLTHATPAHIGAFAHCCKTFPL 80

Query: 408 --SCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500
               P+YAT PV  +G+  + DLY +    + F
Sbjct: 81  FTQIPVYATSPVIALGRTLLQDLYASSPLAATF 113


>UniRef50_A2R7F5 Cluster: Contig An16c0120, complete genome.
           precursor; n=1; Aspergillus niger|Rep: Contig An16c0120,
           complete genome. precursor - Aspergillus niger
          Length = 865

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 3/93 (3%)
 Frame = +3

Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407
           +L++D   K L+D GWD+ FD + ++EL++HV ++  +L++H+ P H+GA  +      L
Sbjct: 21  ILELDGGIKILVDVGWDDTFDPLDLQELEKHVPTLSLILLTHATPAHIGAFAHCCKTFPL 80

Query: 408 --SCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500
               P+YAT PV  +G+  + DLY +    + F
Sbjct: 81  FTQIPVYATSPVIALGRTLLQDLYASSPLAATF 113


>UniRef50_Q5KIP3 Cluster: Cleavage and polyadenylation specificity
           factor subunit, putative; n=1; Filobasidiella
           neoformans|Rep: Cleavage and polyadenylation specificity
           factor subunit, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 899

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 50/181 (27%), Positives = 90/181 (49%), Gaps = 28/181 (15%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPP----CYVLQIDEFKFLLDCGW------DEKFDMVFIKELKRHVN 326
           +I L  LS +  ET P    CY+L++D+ + LLD G        ++    + + ++    
Sbjct: 1   MITLTPLSASAAETSPSEPICYLLELDDARILLDMGQRDYRASSQQCSWDYEEAVRDLAP 60

Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD- 503
           ++  VL+SHS   +L   PYA  + GL+CP+YAT P  +MG++      ++ ++    D 
Sbjct: 61  TLSLVLLSHSSSNYLSLYPYARARWGLTCPVYATQPTVEMGRVVCLAEAESWRSECPVDS 120

Query: 504 -----------------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSL 632
                            + T++++  AFD I  ++Y+Q + + G    L +TP  +GH+L
Sbjct: 121 EKVAADDGSKKPLRGPFVPTVEEIHEAFDWIKAVRYSQPLHLGGDFSHLLLTPFASGHTL 180

Query: 633 G 635
           G
Sbjct: 181 G 181


>UniRef50_A7F0N0 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Sclerotinia sclerotiorum 1980
          Length = 936

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 13/160 (8%)
 Frame = +3

Query: 195 LSGAGEETPPCY-VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLH 368
           L GA  E+     +L++D   K L+D GWDE FD+  ++EL++ + ++  +L++H+   H
Sbjct: 7   LQGAQSESSASQSLLELDGGVKVLIDVGWDETFDVEKLRELEKQIPTLSLILLTHATVPH 66

Query: 369 LGALPYAVGKLGL--SCPIYATLPVYKMGQMFMYDLYQAH-------KNVSEFDLF--TL 515
           + A  +      L    P+YAT PV  +G+  + DLY +           S F L   T 
Sbjct: 67  IAAYAHCCKHFPLFTRIPVYATHPVIALGRTLLQDLYSSTPLASTVIPTTSSFLLQPPTK 126

Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           ++++  F  +  LKY+Q  +      G+ IT   AGHSLG
Sbjct: 127 EEINYYFSLVRPLKYSQPHQPLN---GVTITAYNAGHSLG 163


>UniRef50_A6R733 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 977

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 33/86 (38%), Positives = 52/86 (60%), Gaps = 3/86 (3%)
 Frame = +3

Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407
           +L++D   K L+D GWDE FD+  + EL+R + ++  VL++H+ P H+GA  +      L
Sbjct: 21  ILELDGGVKILVDVGWDESFDVSALAELERQIPTLSLVLLTHATPSHIGAFAHCCKTFPL 80

Query: 408 --SCPIYATLPVYKMGQMFMYDLYQA 479
               PIYAT PV  +G+  + DLY +
Sbjct: 81  FNQIPIYATSPVIALGRTLLQDLYSS 106


>UniRef50_A5DXK9 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 1067

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 45/137 (32%), Positives = 77/137 (56%), Gaps = 6/137 (4%)
 Frame = +3

Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGA---LPYAVGKLGLSC 413
           +E + L D  W    D + +K +++++ SIDA++ISHS    +     L     K+ L+ 
Sbjct: 25  NEHRILADPSWSGS-DALVVKFMEQYLPSIDAIIISHSTTEFISGYILLCIYFPKIMLTI 83

Query: 414 PIYATLPVYKMGQMFMYDLYQAHKNVSEF--DLFTLDDVDMAFDRIVQLKYNQSIEM-KG 584
           P+Y+TLPV ++G++   + Y++   +      L  LD++D  FD+   +KY Q+I +  G
Sbjct: 84  PVYSTLPVNQLGRISTVEYYRSQGVLGPVLSSLIELDEIDNWFDKFKTVKYLQNITLCDG 143

Query: 585 KGLGLRITPLPAGHSLG 635
           K   L +TP  +GHSLG
Sbjct: 144 K---LTMTPYNSGHSLG 157


>UniRef50_A3GHD1 Cluster: Predicted protein; n=3;
           Saccharomycetales|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 934

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 43/136 (31%), Positives = 75/136 (55%), Gaps = 5/136 (3%)
 Frame = +3

Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK---LGLSC 413
           +EF+ L D  W+ K D+  +  +++H+ + + +L+SHS P  +        K   L  + 
Sbjct: 25  NEFRVLADPSWNGK-DVNSVMFMEQHLRNTNIILLSHSTPEFISGYVLMCLKFPNLMANI 83

Query: 414 PIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFDRIVQLKYNQSIEMKGK 587
            +Y+TLPV ++G++   + Y+A+  +   +  L  LD+VD  FD+I  LKY Q + +   
Sbjct: 84  QVYSTLPVNQLGRLSTVEFYRANGMLGPLNTALLELDEVDEWFDKISLLKYLQILNVFDN 143

Query: 588 GLGLRITPLPAGHSLG 635
              + ITP  AGH+LG
Sbjct: 144 --KVVITPYNAGHTLG 157


>UniRef50_Q86A79 Cluster: Similar to Homo sapiens (Human). Cleavage
           and polyadenylation specificity factor, 73 kDa subunit;
           n=2; Dictyostelium discoideum|Rep: Similar to Homo
           sapiens (Human). Cleavage and polyadenylation
           specificity factor, 73 kDa subunit - Dictyostelium
           discoideum (Slime mold)
          Length = 774

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 7/152 (4%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDPL 365
           G+G E    C +L+    K + DCG    +     + F   ++  +  ID +L+SH    
Sbjct: 42  GSGSEVGRSCVLLKYKGKKVMFDCGVHPAYSGLVSLPFFDSIESDIPDIDLLLVSHFHLD 101

Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFD 539
           H  A+PY VGK      ++ T P   +  M + D Y    N++  D  LF   D+D + +
Sbjct: 102 HAAAVPYFVGKTKFKGRVFMTHPTKAIYGMLLSD-YVKVSNITRDDDMLFDKSDLDRSLE 160

Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +I +++Y Q +E      G+++T   AGH LG
Sbjct: 161 KIEKVRYRQKVEHN----GIKVTCFNAGHVLG 188


>UniRef50_UPI00015BD54C Cluster: UPI00015BD54C related cluster; n=1;
           unknown|Rep: UPI00015BD54C UniRef100 entry - unknown
          Length = 451

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 47/165 (28%), Positives = 76/165 (46%), Gaps = 13/165 (7%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359
           +K+     A   T   ++L +D+ K L+DCG  +  D    +EL      +DAVL++H+ 
Sbjct: 1   MKVISYGAAKTVTGSAHMLILDDEKILIDCGLFQGVDEEKSEELGFDPKEVDAVLLTHAH 60

Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL-------YQAHK------NVSEF 500
             H G +P  + K G    IY T P Y++ ++ + D        Y++H        + E 
Sbjct: 61  IDHCGRIPMLI-KNGFKGKIYCTRPTYELSRLMLLDTAKVMLENYKSHMKRFQRGTIKEI 119

Query: 501 DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            L  L D D  F+ +   +   S +     LG ++TP  AGH LG
Sbjct: 120 PLEPLYDEDDVFEALEHFEPTFSYDKTYDILGAKVTPKDAGHILG 164


>UniRef50_Q8SUE4 Cluster: Putative uncharacterized protein
           ECU10_0900; n=1; Encephalitozoon cuniculi|Rep: Putative
           uncharacterized protein ECU10_0900 - Encephalitozoon
           cuniculi
          Length = 730

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 2/154 (1%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD-MVFIKELKR-HVNSIDAVLISH 353
           IK+  L    E    C +++      +LDCG    +  M  +  L    ++ IDAV I+H
Sbjct: 94  IKIMPLGAGNEVGRSCVIVECGGRTIMLDCGVHPAYTGMASLPFLDLVDLSKIDAVFITH 153

Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMA 533
               H  ALP+   K      +Y T P   + +  + D  +     S+ D +T  D+   
Sbjct: 154 FHLDHAAALPFLTEKTSFRGKVYMTHPTKAILKWLLNDYIRIINASSDTDFYTETDLVKC 213

Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +DRI+ + Y+Q + +K    G+++  L AGH LG
Sbjct: 214 YDRIIPIDYHQEVNVK----GIKVKALNAGHVLG 243


>UniRef50_Q6BSP2 Cluster: Similar to CA3384|IPF8362 Candida albicans
           IPF8362; n=1; Debaryomyces hansenii|Rep: Similar to
           CA3384|IPF8362 Candida albicans IPF8362 - Debaryomyces
           hansenii (Yeast) (Torulaspora hansenii)
          Length = 959

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 41/136 (30%), Positives = 75/136 (55%), Gaps = 5/136 (3%)
 Frame = +3

Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK---LGLSC 413
           ++ K L D  W+   +   I  +++++  +D +L+SHS P  +        K   L  + 
Sbjct: 25  NDIKILADPSWNGN-NHNDILYMEQYLKEVDIILLSHSTPEFISGFVLLCIKFPNLMSNI 83

Query: 414 PIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFDRIVQLKYNQSIEMKGK 587
           PIY+TLPV ++G++   + Y+A+  +   +  +  +D+VD  FD+I+ LK+ Q++ +   
Sbjct: 84  PIYSTLPVNQLGRVSTVEYYRANGVLGPLNNSILEVDEVDEWFDKIIPLKFFQTLSVFDN 143

Query: 588 GLGLRITPLPAGHSLG 635
              L ITP  AGH+LG
Sbjct: 144 --RLVITPYNAGHTLG 157


>UniRef50_Q0UZX3 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 934

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 11/85 (12%)
 Frame = +3

Query: 252 KFLLDCGWDEKFDMVFIKELK---------RHVNSIDAVLISHSDPLHLGALPYAVGKLG 404
           K L+D GWDE FD+  +KE++         RHV+++  VL++H+   HLGA  +      
Sbjct: 28  KILIDVGWDESFDVAKLKEIERIQADVLFCRHVSTLSFVLLTHATTAHLGAYVHCCKNFP 87

Query: 405 L--SCPIYATLPVYKMGQMFMYDLY 473
           L    P+YAT+PV  +G+  + DLY
Sbjct: 88  LFSRVPVYATVPVISLGRTLLQDLY 112


>UniRef50_Q4QA79 Cluster: Cleavage and polyadenylation specificity
           factor, putative; n=3; Leishmania|Rep: Cleavage and
           polyadenylation specificity factor, putative -
           Leishmania major
          Length = 828

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 8/147 (5%)
 Frame = +3

Query: 219 PPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398
           P  Y++ ID  + L DCGW+++FD  F+ +LK H+ ++ AV++S       GALP+ +  
Sbjct: 23  PYAYLVDIDGVRILFDCGWNDEFDTSFLNKLKPHLPTVHAVVLSSPHITACGALPFVLSH 82

Query: 399 LGLSCPIYATLPVYKMG-----QMFMYDLYQAHK-NVSEFDLFTL--DDVDMAFDRIVQL 554
           +     + A     K+G       F+Y    +H   +++ + FT+  D +  +F R ++ 
Sbjct: 83  ISPGTFVAAAGGTSKIGVHSVLHSFLYQYPNSHTFTLADGEAFTMTVDSIYHSF-RSLRE 141

Query: 555 KYNQSIEMKGKGLGLRITPLPAGHSLG 635
            Y   + +K   + +    + AG  LG
Sbjct: 142 PYGGKVTVKNDDVEVNCFAVFAGRMLG 168


>UniRef50_O13794 Cluster: Endoribonuclease ysh1; n=2;
           Ascomycota|Rep: Endoribonuclease ysh1 -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 775

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 44/150 (29%), Positives = 72/150 (48%), Gaps = 5/150 (3%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDPL 365
           GAG E    C+V+Q      +LD G    +     + F  E    ++++D +LISH    
Sbjct: 43  GAGNEVGRSCHVIQYKGKTVMLDAGVHPAYTGLSALPFFDEFD--LSTVDVLLISHFHLD 100

Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRI 545
           H+ +LPY + K      ++ T P   + +  + D  +      E  L+   D+  AFDRI
Sbjct: 101 HVASLPYVMQKTNFRGRVFMTHPTKAVCKWLLSDYVKVSNVGMEDQLYDEKDLLAAFDRI 160

Query: 546 VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             + Y+ +IE++    G++ TP  AGH LG
Sbjct: 161 EAVDYHSTIEVE----GIKFTPYHAGHVLG 186


>UniRef50_Q12102 Cluster: Protein CFT2; n=4; Saccharomyces
           cerevisiae|Rep: Protein CFT2 - Saccharomyces cerevisiae
           (Baker's yeast)
          Length = 859

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 9/153 (5%)
 Frame = +3

Query: 192 CLSGAGEETPPCYVLQIDEFKFLLDCGWDEK---FDMVFIKELKRHVNSIDAVLISHSDP 362
           C  G+G  T    V++ D    L+D GW+     ++   IK  ++ +  ID +++S    
Sbjct: 8   CDDGSG--TTVGSVVRFDNVTLLIDPGWNPSKVSYEQC-IKYWEKVIPEIDVIILSQPTI 64

Query: 363 LHLGA---LPYAVGKLGLS-CPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLD--DV 524
             LGA   L Y      +S   +YATLPV  +G++   D Y +   +  +D   LD  D+
Sbjct: 65  ECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTIDSYASAGVIGPYDTNKLDLEDI 124

Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAG 623
           +++FD IV LKY+Q ++++ +  GL +    AG
Sbjct: 125 EISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAG 157


>UniRef50_Q18IP5 Cluster: Predicted metal-dependent RNase, consists
           of a metallo-beta-lactamase domain and an RNA-binding KH
           domain; n=1; Haloquadratum walsbyi DSM 16790|Rep:
           Predicted metal-dependent RNase, consists of a
           metallo-beta-lactamase domain and an RNA-binding KH
           domain - Haloquadratum walsbyi (strain DSM 16790)
          Length = 538

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGA 377
           G G+E    CY LQ  ++ + +DCG  +     +          IDAV I+H+   H+G 
Sbjct: 10  GGGDEVGRSCYHLQAGDYDYFIDCGLKQSETPEYPLFEDVSQGQIDAVFITHAHIDHIGG 69

Query: 378 LPYAV--GKLGLSCPIYATLPVYKMGQMFMYDLYQAHK----NVSEFDLFTLDDVDMAFD 539
           LP A   G L     I+ T P   +  + ++D  Q HK     +++   FT  D++    
Sbjct: 70  LPVAEHHGLLDDDASIFMTRPTNALASILLHDSLQIHKQETAELNQPQQFTATDIEQVLS 129

Query: 540 RIVQLKYNQS 569
           RI+ + YN++
Sbjct: 130 RIMTIGYNRN 139


>UniRef50_Q750X1 Cluster: AGL182Cp; n=1; Eremothecium gossypii|Rep:
           AGL182Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 803

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 41/157 (26%), Positives = 72/157 (45%), Gaps = 8/157 (5%)
 Frame = +3

Query: 189 HCLSGAGEETPPCYVLQIDEFKFLLDCGWDE--KFDMVFIKELKRHVNSIDAVLISHSDP 362
           +C   +G  T    +L  D    L+D GW     +D   +   K  +  +D +L+S    
Sbjct: 7   YCKDESGSTTGT--ILSFDNCTLLIDPGWSGGCSYDEC-MAYWKEWIPQVDIILLSQPIQ 63

Query: 363 LHLGALPYA----VGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLD--DV 524
             +GA        +        +Y+TLPV  +G++   DLY +   +  FD   +D  D+
Sbjct: 64  ECIGAYAALFFDYISHFNSRIQVYSTLPVANLGRVATVDLYASLGIIGPFDTNRIDIEDI 123

Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           D AFD +  +KY+Q +++K +  GL +    +G + G
Sbjct: 124 DTAFDHLNTVKYSQLVDLKSRFDGLSLVAYSSGFAPG 160


>UniRef50_Q387M8 Cluster: Cleavage and polyadenylation specificity
           factor, putative; n=2; Trypanosoma|Rep: Cleavage and
           polyadenylation specificity factor, putative -
           Trypanosoma brucei
          Length = 818

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 40/149 (26%), Positives = 74/149 (49%), Gaps = 10/149 (6%)
 Frame = +3

Query: 219 PPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398
           P  Y+L+ID  + L+DCGW++ F+  ++  L  ++  + AVL S  +    GALP+ +  
Sbjct: 28  PMAYLLEIDGVRILMDCGWNDGFETSYLDALLPYLGDLHAVLFSTPELSSCGALPFVMEH 87

Query: 399 LGLSCPIYATLPVYKMG-----QMFMY-----DLYQAHKNVSEFDLFTLDDVDMAFDRIV 548
           +     + A     KMG       F+Y     + ++    V EF++ T+D +  AF R V
Sbjct: 88  ITAETHVAAAGATAKMGLHGLLHPFLYLFPNTNTWKLQSGV-EFEM-TVDKIYSAF-RSV 144

Query: 549 QLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +  Y   + ++ + + +   P+ +G  LG
Sbjct: 145 REPYGGKVTIRHRDVEVECFPVFSGRMLG 173


>UniRef50_Q5TA45 Cluster: Integrator complex subunit 11; n=29;
           Eukaryota|Rep: Integrator complex subunit 11 - Homo
           sapiens (Human)
          Length = 600

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 45/154 (29%), Positives = 72/154 (46%), Gaps = 9/154 (5%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356
           GAG++    C ++ I     +LDCG       D +F D  +I +  R  + +D V+ISH 
Sbjct: 10  GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 69

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ-AHKNVSEFDLFTLDDVDMA 533
              H GALPY    +G   PIY T P   +  + + D  + A     E + FT   +   
Sbjct: 70  HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDC 129

Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             ++V +  +Q++++  +   L I    AGH LG
Sbjct: 130 MKKVVAVHLHQTVQVDDE---LEIKAYYAGHVLG 160


>UniRef50_A7APS1 Cluster: Putative uncharacterized protein; n=1;
           Babesia bovis|Rep: Putative uncharacterized protein -
           Babesia bovis
          Length = 943

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 41/136 (30%), Positives = 66/136 (48%), Gaps = 10/136 (7%)
 Frame = +3

Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP--YA---VGKLGLSCP-I 419
           L++CGW   F+   I  LK+  + +D ++++  D  H+GALP  Y+   V + GL  P I
Sbjct: 98  LVNCGWSLDFEPESIDLLKQCCSDVDVIILTDGDFGHVGALPVIYSWLHVVRDGLGLPSI 157

Query: 420 YATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGL 599
             T   YK  +  + D+        +F+ +   D+D+ +   V L+Y +S      G G 
Sbjct: 158 LCTEGCYKFARACLVDVLDNATLSYKFEGYNFSDLDLFYSGCVTLRYRESFPFVKSGEGW 217

Query: 600 RI----TPLPAGHSLG 635
           RI     PL  G S+G
Sbjct: 218 RIHISLLPLNNGVSIG 233


>UniRef50_Q7S0J8 Cluster: Putative uncharacterized protein
           NCU06869.1; n=4; Sordariomycetes|Rep: Putative
           uncharacterized protein NCU06869.1 - Neurospora crassa
          Length = 1002

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
 Frame = +3

Query: 231 VLQIDE-FKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG- 404
           +L++D   K L+D GWDE FD+  +KEL +   ++  +L++H+   HL A  +       
Sbjct: 20  LLELDGGVKILIDVGWDETFDVEKLKELGKQAPTLSLILLTHATVPHLAAYAHCCKHFPP 79

Query: 405 -LSCPIYATLPVYKMGQMFMYDLY 473
               P+YAT PV  +G+    DLY
Sbjct: 80  FQRIPVYATRPVIDLGRTLTQDLY 103


>UniRef50_Q74MJ3 Cluster: NEQ076; n=1; Nanoarchaeum equitans|Rep:
           NEQ076 - Nanoarchaeum equitans
          Length = 635

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 44/158 (27%), Positives = 76/158 (48%), Gaps = 6/158 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKF-----DMVFIKELKRH-VNSIDAV 341
           +++  L GA +      +LQ  E + LLD G D        +   I EL    V  +DAV
Sbjct: 189 VRVSFLGGASQVGRSALLLQTKESRILLDFGVDLSLPPNNKNAYPIVELPEFDVKELDAV 248

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDD 521
           +I+H+   H+G +P+ + K+G   P+Y T P   +  + + D Y    N +   LF+ DD
Sbjct: 249 VITHAHLDHVGFVPF-LYKMGYKGPVYLTPPTLDIATLSLLD-YLRIANENNVKLFSGDD 306

Query: 522 VDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +       + ++Y Q+ ++      +++T   AGH LG
Sbjct: 307 IRNFVKHSITIEYGQTTDIAS---DVKLTFYNAGHILG 341


>UniRef50_A3ERC5 Cluster: Putative RNA-processing exonuclease; n=1;
           Leptospirillum sp. Group II UBA|Rep: Putative
           RNA-processing exonuclease - Leptospirillum sp. Group II
           UBA
          Length = 479

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 3/87 (3%)
 Frame = +3

Query: 216 TPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAVLISHSDPLHLGALPY 386
           T  C++L +D F+ L+DCG  +  D +F   LK      +SI AV+++H+   H G LP 
Sbjct: 13  TGSCHLLDVDGFRILIDCGLFQGEDELFSSNLKPFGFEPSSISAVILTHAHLDHCGRLPT 72

Query: 387 AVGKLGLSCPIYATLPVYKMGQMFMYD 467
            V + G   P+YAT P   + ++ ++D
Sbjct: 73  LV-RQGFRGPVYATSPTRYLTEIVLWD 98


>UniRef50_A4CGY6 Cluster: Putative uncharacterized protein; n=4;
           Flavobacteriales|Rep: Putative uncharacterized protein -
           Robiginitalea biformata HTCC2501
          Length = 458

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAVLIS 350
           I +H L  AG  T   Y+L   + K L+DCG  +    + +K  +    +V  IDAVL++
Sbjct: 6   INIHFLGAAGTVTGSKYLLDTGDRKILIDCGLFQGLKELRLKNWEYPPVNVTEIDAVLLT 65

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497
           H    H G LP  V K G   PIY T P   + ++ + D  +  +  +E
Sbjct: 66  HGHLDHTGYLPRLV-KQGFKGPIYGTYPTLDIAKIILNDSAKIQEQEAE 113


>UniRef50_Q9U3K2 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 608

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356
           GAG++    C ++ I     ++DCG       D +F D  +I    R  + +D V+ISH 
Sbjct: 14  GAGQDVGRSCILITIGGKNIMVDCGMHMGYQDDRRFPDFSYIGGGGRLTDYLDCVIISHF 73

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNV-SEFDLFTLDDVDMA 533
              H G+LP+    +G   PIY T P   +  + + D  +   ++  E + FT DD+   
Sbjct: 74  HLDHCGSLPHMSEIVGYDGPIYMTYPTKAICPVLLEDYRKVQCDIKGETNFFTSDDIKNC 133

Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             ++V    ++ I +  +   L I    AGH LG
Sbjct: 134 MKKVVGCALHEIIHVDNE---LSIRAFYAGHVLG 164


>UniRef50_Q8GUU3 Cluster: FEG protein; n=8; Magnoliophyta|Rep: FEG
           protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 613

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 44/160 (27%), Positives = 71/160 (44%), Gaps = 10/160 (6%)
 Frame = +3

Query: 186 LHCLS-GAGEET-PPCYVLQIDEFKFLLDCGWDEKFD-------MVFIKELKRHVNSIDA 338
           + CL  GAG+E    C V+ I+  K + DCG     D          I +     N+I  
Sbjct: 3   IDCLVLGAGQEIGKSCVVVTINGKKIMFDCGMHMGCDDHNRYPNFSLISKSGDFDNAISC 62

Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAH-KNVSEFDLFTL 515
           ++I+H    H+GALPY     G + PIY + P   +  + + D  +       E +LFT 
Sbjct: 63  IIITHFHMDHVGALPYFTEVCGYNGPIYMSYPTKALSPLMLEDYRRVMVDRRGEEELFTT 122

Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             +     +++ +   Q+I++      L+I    AGH LG
Sbjct: 123 THIANCMKKVIAIDLKQTIQVDE---DLQIRAYYAGHVLG 159


>UniRef50_A6NEN7 Cluster: Uncharacterized protein CPSF3L; n=16;
           Theria|Rep: Uncharacterized protein CPSF3L - Homo
           sapiens (Human)
          Length = 277

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 39/136 (28%), Positives = 65/136 (47%), Gaps = 9/136 (6%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356
           GAG++    C ++ I     +LDCG       D +F D  +I +  R  + +D V+ISH 
Sbjct: 10  GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 69

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ-AHKNVSEFDLFTLDDVDMA 533
              H GALPY    +G   PIY T P   +  + + D  + A     E + FT   +   
Sbjct: 70  HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDC 129

Query: 534 FDRIVQLKYNQSIEMK 581
             ++V +  +Q++++K
Sbjct: 130 MKKVVAVHLHQTVQIK 145


>UniRef50_A4XI93 Cluster: Beta-lactamase domain protein; n=1;
           Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
           Beta-lactamase domain protein - Caldicellulosiruptor
           saccharolyticus (strain ATCC 43494 / DSM 8903)
          Length = 821

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 41/148 (27%), Positives = 66/148 (44%), Gaps = 1/148 (0%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLG 374
           L GA E    C +++      LLD G   K D +   +L R +   D  LISH+   H+G
Sbjct: 6   LGGAKEVGASCVLIKAGGKNILLDSGIRMKEDKLPNLQLLRELGGADVCLISHAHLDHIG 65

Query: 375 ALPYAVGKLGLSCPIYATLPVYKMGQMFMYD-LYQAHKNVSEFDLFTLDDVDMAFDRIVQ 551
           +LP  + +       Y   P   + ++ +YD L        E  ++   +V+   DR + 
Sbjct: 66  SLP-LIAREYPHIFFYTNQPTKDLIKVLLYDSLKIMDAKEDEIPIYAEKNVEDLLDRTIT 124

Query: 552 LKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             +N + E      G+++T  PAGH LG
Sbjct: 125 YGFNYTFEPLE---GIKVTFFPAGHILG 149


>UniRef50_A4S2M5 Cluster: Predicted protein; n=4; Viridiplantae|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 767

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 37/151 (24%), Positives = 71/151 (47%), Gaps = 6/151 (3%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKF----DMVFIKELKRHVNSIDAVLISHSDPL 365
           GAG E    C + +  +   + DCG    +     + +  E+   +  +DA+ ++H    
Sbjct: 18  GAGSEVGRSCVIARYKQKTLMFDCGIHPGYAGLASLPYFDEID--LADVDALFVTHFHLD 75

Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD-LFTLDDVDMAFDR 542
           H  A+P+  G+   +  I+ T P   +  M M D  +  KN    + LF   D++ +  +
Sbjct: 76  HCAAVPFLCGRTDFNGRIFMTHPTKAIYHMLMQDFCRLLKNQEPSEQLFGEKDLEASMKK 135

Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           I  + ++Q +++     G+++TP  AGH LG
Sbjct: 136 IEVIDFHQEVDVD----GVKVTPYRAGHVLG 162


>UniRef50_Q5TA51 Cluster: Cleavage and polyadenylation specific
           factor 3-like; n=2; Homo sapiens|Rep: Cleavage and
           polyadenylation specific factor 3-like - Homo sapiens
           (Human)
          Length = 308

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 9/139 (6%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356
           GAG++    C ++ I     +LDCG       D +F D  +I +  R  + +D V+ISH 
Sbjct: 29  GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 88

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ-AHKNVSEFDLFTLDDVDMA 533
              H GALPY    +G   PIY T P   +  + + D  + A     E + FT   +   
Sbjct: 89  HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDC 148

Query: 534 FDRIVQLKYNQSIEMKGKG 590
             ++V +  +Q+++++  G
Sbjct: 149 MKKVVAVHLHQTVQVRFPG 167


>UniRef50_Q4UDL0 Cluster: Putative uncharacterized protein; n=3;
           Theileria|Rep: Putative uncharacterized protein -
           Theileria annulata
          Length = 830

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 30/110 (27%), Positives = 57/110 (51%), Gaps = 6/110 (5%)
 Frame = +3

Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKL-----GLSCP-I 419
           LL+CGW   F    +   K++  ++D +LI+  D LH GAL +   +      G S P I
Sbjct: 39  LLNCGWSLDFSEEKLNLYKKYAQNVDVILITDGDFLHSGALLWLTSRFLTELKGKSIPKI 98

Query: 420 YATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQS 569
             T   YK  +  + D+ +     ++F  +++DD+++     V+L+Y+++
Sbjct: 99  LCTEGTYKFMRASLIDVLENVTFSTDFGYYSMDDLELLDSNCVKLRYSET 148


>UniRef50_Q9YEQ9 Cluster: Putative exonuclease; n=1; Aeropyrum
           pernix|Rep: Putative exonuclease - Aeropyrum pernix
          Length = 671

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 6/161 (3%)
 Frame = +3

Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD------EKFDMVFIKELKRHVNSI 332
           T  +++  L   GE      ++   E K LLD G        + +   +  E +  V+ +
Sbjct: 189 TRHVRVVGLGSFGEVGRSAILVDTGESKVLLDAGLSPSGYGPDSYPYYWSPEFR--VDEL 246

Query: 333 DAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFT 512
           DAV+ISH+   H+G LP    K G   P+YAT P   +  + + DL    +       F 
Sbjct: 247 DAVVISHAHLDHVGTLPLLF-KYGFRGPVYATPPTRDIMIIVLRDLINLMRKAQGEPPFE 305

Query: 513 LDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             DV+ A  R++ + YN   ++      +++T + AGH LG
Sbjct: 306 PRDVEKALTRLIPVNYNTVTDV---APDIKMTFINAGHILG 343


>UniRef50_Q5BEP0 Cluster: Endoribonuclease ysh1; n=15;
           Pezizomycotina|Rep: Endoribonuclease ysh1 - Emericella
           nidulans (Aspergillus nidulans)
          Length = 884

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD---EKFDMV-FIKELKRHVNSIDAVLI 347
           +  +CL G  E    C+++Q      +LD G     E F  + F  E    ++++D +LI
Sbjct: 24  LAFYCLGGGNEVGRSCHIIQYKGKTVMLDAGMHPAKEGFSALPFFDEFD--LSTVDILLI 81

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD----LFTL 515
           SH    H  ALPY + K      ++ T     + +  + D  + +   S  D    L+T 
Sbjct: 82  SHFHVDHSSALPYVLSKTNFKGRVFMTHATKAIYKWLIQDNVRVNNTASSSDQRTTLYTE 141

Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            D       I  + +N +  +      +RITP PAGH LG
Sbjct: 142 HDHLSTLPLIETIDFNTTHTIN----SIRITPYPAGHVLG 177


>UniRef50_Q6FW78 Cluster: Candida glabrata strain CBS138 chromosome
           D complete sequence; n=1; Candida glabrata|Rep: Candida
           glabrata strain CBS138 chromosome D complete sequence -
           Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 843

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 9/144 (6%)
 Frame = +3

Query: 231 VLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN---SIDAVLISHSDPLHLGALPYA---- 389
           +L+ D    LLD GW   + + +   +    N    +D +LIS      LGA  +     
Sbjct: 19  ILRFDNVTILLDPGWSS-YKVSYEDSVAFWSNIIAEVDIILISQPTTECLGAYTFLYYNF 77

Query: 390 VGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL--FTLDDVDMAFDRIVQLKYN 563
           +        +YATLPV  +G++   + Y     +  +      +DDV+ AFD I  LKY+
Sbjct: 78  ISHFISHIQVYATLPVANLGRVSTIEFYVTKGIIGPYQTNQLDIDDVEKAFDFIDVLKYS 137

Query: 564 QSIEMKGKGLGLRITPLPAGHSLG 635
           Q ++++ K  GL +    +G++ G
Sbjct: 138 QLVDLRSKYDGLSLFAYNSGYAPG 161


>UniRef50_Q4Q2K1 Cluster: Cleavage and polyadenylation specificity
           factor, putative; n=7; Trypanosomatidae|Rep: Cleavage
           and polyadenylation specificity factor, putative -
           Leishmania major
          Length = 756

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 4/151 (2%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCG---WDEKFDMV-FIKELKRHVNSIDAVLISHSDP 362
           +   GE    C V+Q      +LDCG        D + F   +K   + ID VLI+H   
Sbjct: 31  IGSGGEVGRSCVVVQYKGRGVMLDCGNHPAKSGLDSLPFFDSIK--CDEIDVVLITHFHL 88

Query: 363 LHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDR 542
            H GALPY   +      ++ T       +M M D  +     S  DL T + +    DR
Sbjct: 89  DHCGALPYFCNQTSFKGRVFMTSATKAFYKMVMNDFLRIGAGAS--DLVTSEWLQSTIDR 146

Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           I  ++Y++ + +     G+   P  AGH LG
Sbjct: 147 IETVEYHEEVTVN----GISFQPFNAGHVLG 173


>UniRef50_A2FCF8 Cluster: RNA-metabolising metallo-beta-lactamase
           family protein; n=1; Trichomonas vaginalis G3|Rep:
           RNA-metabolising metallo-beta-lactamase family protein -
           Trichomonas vaginalis G3
          Length = 679

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 41/151 (27%), Positives = 74/151 (49%), Gaps = 6/151 (3%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDPL 365
           GAG+E    C +L+    + +LDCG    ++    + FI  +      ID +LI+H    
Sbjct: 17  GAGQEVGRSCIILKYHRKRVMLDCGIHPAYENFGGLPFIDAIDPA--KIDVLLITHFHID 74

Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD-LYQAHKNVSEFDLFTLDDVDMAFDR 542
           H+ A+P+ + +   S P + T     + +  + D +  + +   E +LFT  DV    + 
Sbjct: 75  HITAVPWFLTQTNFSGPCFMTHTTKTISKTLLVDYVGVSGRGSEEPNLFTRADVANVQNM 134

Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           I  + Y+Q++  +    G+++T  PAGH LG
Sbjct: 135 ITAVNYHQTVTHQ----GIKMTCYPAGHVLG 161


>UniRef50_A0BGT5 Cluster: Chromosome undetermined scaffold_106,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_106,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 690

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 40/151 (26%), Positives = 65/151 (43%), Gaps = 6/151 (3%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWD---EKFDMVFIKELKR--HVNSIDAVLISHSDP 362
           GAG E    C +LQ  E + + DCG     E   ++ +    +   +  ID +LI+H   
Sbjct: 14  GAGNEVGRSCILLQFQEKQIMFDCGIHMNKENKGVMALPYFNKIDKIEDIDLILITHFHL 73

Query: 363 LHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDR 542
            H GALPY +        IY T P  ++  + + D  +        DL     ++ +   
Sbjct: 74  DHCGALPYFLKNYKFKGKIYMTTPTKEIYGLVLKDSIKVKSEDFSQDLINEQSIEQSLKN 133

Query: 543 IVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           I  + Y+Q I  +    G+++    AGH LG
Sbjct: 134 IDCIDYDQEIHYQ----GIKLKCYNAGHVLG 160


>UniRef50_A1RWY8 Cluster: Beta-lactamase domain protein; n=1;
           Thermofilum pendens Hrk 5|Rep: Beta-lactamase domain
           protein - Thermofilum pendens (strain Hrk 5)
          Length = 639

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 3/138 (2%)
 Frame = +3

Query: 231 VLQIDEFKFLLDCGWDE--KFDMVFIKELKRH-VNSIDAVLISHSDPLHLGALPYAVGKL 401
           ++Q  E   LLD G       D + + +L    + S+DAV+I+H+   H+GALP  + K 
Sbjct: 197 LVQTPEANILLDAGLKPTGNGDELPLFDLPEFDLESLDAVVITHAHLDHVGALP-VLFKY 255

Query: 402 GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMK 581
           G   P+Y T P   + ++   D  +  +   + +L+++ DV+        L Y +  ++ 
Sbjct: 256 GYKGPVYMTEPTLHLSKLLFEDYIKVAQREGKNELYSMRDVNSLLLNTYTLSYGEVTDIA 315

Query: 582 GKGLGLRITPLPAGHSLG 635
            +   +R+T   AGH LG
Sbjct: 316 PE---IRLTFYRAGHILG 330


>UniRef50_A5ZRP6 Cluster: Putative uncharacterized protein; n=4;
           Bacteria|Rep: Putative uncharacterized protein -
           Ruminococcus obeum ATCC 29174
          Length = 539

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 14/166 (8%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359
           +K+  +    E T  CY L+    KFL+DCG ++  D    +++    + +D VL++H+ 
Sbjct: 1   MKITFIGATHEVTGSCYYLEAAGKKFLVDCGMEQGPDYYENQDIPVKGSDLDFVLLTHAH 60

Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD-----LYQA--------HKNVSEF 500
             H G LP A+   G   PIYAT     +  + + D     +++A         +   EF
Sbjct: 61  MDHSGNLP-AIYAKGFQGPIYATQATCHLCDIMLRDSAHIQMFEAEWRNRKGRRQGKPEF 119

Query: 501 -DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
              +T++D        V   Y ++I+   +G+ +R   + AGH LG
Sbjct: 120 VPAYTMEDAMGVIQNFVPCPYEKTIK-PAEGISVRF--VDAGHLLG 162


>UniRef50_A3HWA3 Cluster: Metallo-beta-lactamase family protein;
           n=1; Algoriphagus sp. PR1|Rep: Metallo-beta-lactamase
           family protein - Algoriphagus sp. PR1
          Length = 482

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRH---VNSIDAVLISHSDPL 365
           L GAG  T   Y++ + +F+FL+DCG  +    +  +   +       ++A++++H+   
Sbjct: 24  LGGAGAVTGSKYLIDLGDFEFLVDCGLYQGAKNLRKRNWDKFPMPPTDMEAIILTHAHLD 83

Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF-------------DL 506
           H+G LP  V K G   PIY T    ++ ++ + D  +  +  +E+              L
Sbjct: 84  HVGYLPKLV-KQGFKGPIYCTEATAELAKILLLDSGKLQEEEAEYARKKGYSRHESPEPL 142

Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +T DD +  F ++V  ++    ++      + +T   AGH LG
Sbjct: 143 YTRDDAESVFPQLVPQQFETPFQINP---NVSVTYYHAGHILG 182


>UniRef50_A2D958 Cluster: RNA-metabolising metallo-beta-lactamase
           family protein; n=1; Trichomonas vaginalis G3|Rep:
           RNA-metabolising metallo-beta-lactamase family protein -
           Trichomonas vaginalis G3
          Length = 588

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 44/156 (28%), Positives = 66/156 (42%), Gaps = 5/156 (3%)
 Frame = +3

Query: 183 KLHCLSGAGEETPPCYVLQIDEFKFLLDCG-----WDEKFDMVFIKELKRHVNSIDAVLI 347
           +L C    GE      +++I   K LLDCG      DEK  +   ++       +D VLI
Sbjct: 14  QLICFGAGGEVGRSSILVEIGSKKVLLDCGVNFTATDEKDRLPAYQD---PFPKVDLVLI 70

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           SH    HL A+PY    L    P+Y T    +  QM M  +      V+E   +  +D+ 
Sbjct: 71  SHIHTDHLAAVPYLTEVLKCQAPVYMT----RASQMMMPIMLDDFLKVTENPPYKAEDLT 126

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
               +I  +++    E      G+ +   PAGH LG
Sbjct: 127 NCKPKIKVVEFYSRFE---AAPGIFVQAFPAGHILG 159


>UniRef50_Q6CNJ8 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome E of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 812

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 36/142 (25%), Positives = 71/142 (50%), Gaps = 7/142 (4%)
 Frame = +3

Query: 231 VLQIDEFKFLLDCGWDEKFDMVFIKEL-KRHVNSIDAVLISHSDPLHLGALPYAVGKL-- 401
           +++ +    LLD GW+ +      +E   ++++ +D VLIS      LG+      +   
Sbjct: 19  IVRFNNVIVLLDPGWNGEGSYEECEEFWTQYISEVDIVLISQPTIECLGSYAMMFKQFLP 78

Query: 402 --GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD--LFTLDDVDMAFDRIVQLKYNQS 569
                  +Y TLPV  +G++   DL  +   +  F   +  L+D++ +FD I  +KY+Q+
Sbjct: 79  HFRSRIQVYGTLPVSNLGRVNSVDLLTSVGILGPFSNAVMDLEDIESSFDLIETVKYSQT 138

Query: 570 IEMKGKGLGLRITPLPAGHSLG 635
           +++K K  GL +    +G++ G
Sbjct: 139 VDLKNKFDGLSLEAHNSGYAPG 160


>UniRef50_Q2LYC2 Cluster: Metallo-beta-lactamase protein; n=6;
           Deltaproteobacteria|Rep: Metallo-beta-lactamase protein
           - Syntrophus aciditrophicus (strain SB)
          Length = 541

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 43/170 (25%), Positives = 74/170 (43%), Gaps = 17/170 (10%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV---NSIDAVLI 347
           I+K+  L  A   T  CY+L+    +F +DCG  +  + +  +     +     I+  LI
Sbjct: 6   IMKIKFLGAARTVTGSCYILETQGHRFAIDCGMHQGNEEIEKRNWNVELYEPEKIEFFLI 65

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF--------- 500
           +H+   H G LP  V K G   PIYAT P   + ++ + D     +  +++         
Sbjct: 66  THAHIDHTGLLPRLVQK-GFRGPIYATQPTVDLLRILLLDSAHIQEMEAQWKSRKRLRFG 124

Query: 501 -----DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
                 L+T  D +  F  +  + Y++  E      GL++  + AGH LG
Sbjct: 125 EKRVGPLYTQRDAEAVFPMLKSVSYDKPFE---PFPGLKVNFMDAGHILG 171


>UniRef50_A5N1D0 Cluster: Putative uncharacterized protein; n=1;
           Clostridium kluyveri DSM 555|Rep: Putative
           uncharacterized protein - Clostridium kluyveri DSM 555
          Length = 832

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 36/125 (28%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELK--RHVNSIDAVLISHSDPLH 368
           L GA E    C +++I     L+DCG  +      + + K  +    IDA++ISHS   H
Sbjct: 10  LGGAREVGGSCILVKIYNRNILMDCGIRQSSSKDALPDFKSIQEQGGIDAIIISHSHMDH 69

Query: 369 LGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKN-VSEFDLFTLDDVDMAFDRI 545
           +G+LP    +  L+  IYAT     + ++ +YD  +   N   E  L+   DV    + I
Sbjct: 70  IGSLPIISKEYPLA-RIYATKMTKDLMRVLLYDSLKIMNNREGEIPLYAESDVKNMLNSI 128

Query: 546 VQLKY 560
             + Y
Sbjct: 129 FPINY 133


>UniRef50_Q06224 Cluster: Endoribonuclease YSH1; n=10; Fungi/Metazoa
           group|Rep: Endoribonuclease YSH1 - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 779

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
 Frame = +3

Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDA 338
           T+  K   L G+ E    C++LQ      +LD G    +     + F  E    ++ +D 
Sbjct: 6   TTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFD--LSKVDI 63

Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ--------AHKNVS 494
           +LISH    H  +LPY + +      ++ T P   + +  + D  +        +     
Sbjct: 64  LLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTK 123

Query: 495 EFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +  LF+ +D+  +FD+I  + Y+ ++++     G++ T   AGH LG
Sbjct: 124 DEGLFSDEDLVDSFDKIETVDYHSTVDVN----GIKFTAFHAGHVLG 166


>UniRef50_Q95PY8 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 707

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 40/152 (26%), Positives = 71/152 (46%), Gaps = 7/152 (4%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMV----FIKELKRHVNSIDAVLISHSDPL 365
           G+G+E    C++L+    + +LDCG       V    F+  ++  + +ID +LI+H    
Sbjct: 17  GSGQEVGRSCHLLEYKGKRVMLDCGVHPGLHGVDALPFVDFVE--IENIDLLLITHFHLD 74

Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK--NVSEFDLFTLDDVDMAFD 539
           H GALP+ + K       + T     + +M + D  +  K        L+T DD++ +  
Sbjct: 75  HCGALPWLLQKTAFQGKCFMTHATKAIYRMLLGDYVRISKYGGPDRNQLYTEDDLEKSMA 134

Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +I  + + +  E+     G+R  P  AGH LG
Sbjct: 135 KIETIDFREQKEVN----GIRFWPYVAGHVLG 162


>UniRef50_A7TEK7 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 821

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 37/143 (25%), Positives = 68/143 (47%), Gaps = 8/143 (5%)
 Frame = +3

Query: 231 VLQIDEFKFLLDCGWDEKFDMVF--IKELKRHVNSIDAVLISHSDPLHLGA---LPYA-V 392
           +++ D    L+D  W+ K       IK     +  +D +L+S      LGA   L Y  V
Sbjct: 19  IVRFDNVTILIDPSWNGKNVSYADSIKYWSTIIPEVDIILLSQPSLECLGAYSMLYYNFV 78

Query: 393 GKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL--FTLDDVDMAFDRIVQLKYNQ 566
                   +YATLPV  +G++ + + Y     +  ++     L+D++ +FD I  +KY+Q
Sbjct: 79  SHFVSRIDVYATLPVSNLGRISVIEQYACAGIIGPYETNEMDLEDIEKSFDNIKTVKYSQ 138

Query: 567 SIEMKGKGLGLRITPLPAGHSLG 635
            ++++ K  GL +    +G + G
Sbjct: 139 LVDLRSKFDGLTLVAYNSGVNAG 161


>UniRef50_Q58633 Cluster: Uncharacterized protein MJ1236; n=16;
           Euryarchaeota|Rep: Uncharacterized protein MJ1236 -
           Methanococcus jannaschii
          Length = 634

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 37/157 (23%), Positives = 68/157 (43%), Gaps = 5/157 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-----WDEKFDMVFIKELKRHVNSIDAVL 344
           I++  L GA E    C  +Q  + + L+DCG      D+ F      E    +  +DAV+
Sbjct: 180 IRVSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACEDKAFPHFDAPEFS--IEDLDAVI 237

Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDV 524
           ++H+   H G +P  + + G   P+Y T P   +  +   D  +  K   +   +T  D+
Sbjct: 238 VTHAHLDHCGFIP-GLFRYGYDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTSKDI 296

Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
                  + + Y  + ++      +++T   AGH LG
Sbjct: 297 KTCVKHTIPIDYGVTTDISPT---IKLTLHNAGHVLG 330


>UniRef50_Q24CH6 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 749

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 10/141 (7%)
 Frame = +3

Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVG-----KLGL 407
           +E   LLDCG +   D     +    +  +D +L+SH    ++GALP+ +        G 
Sbjct: 25  EEIYILLDCGLNSNMDFTAYWQNIEKLKKVDMILLSHVGAEYVGALPFLLNNKQIMSQGK 84

Query: 408 SCPIYATLPVYKMGQMFMYDLY-QAHKNVSEFDLF----TLDDVDMAFDRIVQLKYNQSI 572
           +  IY+T PV K+G    Y+ Y       SE +      +     +A+DR   +++ Q  
Sbjct: 85  NIRIYSTTPVMKLGMFNSYNQYLNTMMLASEEETLVTEKSFQKFYIAYDRCKVIQFFQKK 144

Query: 573 EMKGKGLGLRITPLPAGHSLG 635
            +  K   + I+P   G++LG
Sbjct: 145 VVHIKDKDIIISPNCIGNTLG 165


>UniRef50_A7DQ83 Cluster: Beta-lactamase domain protein; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Beta-lactamase domain protein - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 646

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 5/157 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD----EKFD-MVFIKELKRHVNSIDAVL 344
           + L+ L G G+      +L   E K L+DCG +       D    +  L   ++ +DAV+
Sbjct: 189 VSLYTLGGFGQVGRSSLLLSTPESKILIDCGINPGARSPMDAFPRLDSLNLTLDDLDAVV 248

Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDV 524
           I H+   H G LP  + K G   PIY T P   M  +   D  +         +++  DV
Sbjct: 249 IGHAHLDHTGFLP-TLCKYGYKGPIYCTEPTLPMMNLIQLDAIKVAAAQGRTPIYSERDV 307

Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
                + + L Y    ++      +++    AGH LG
Sbjct: 308 KQIMRQTITLPYGTVTDISP---DIKLVLANAGHILG 341


>UniRef50_Q5CRW9 Cluster: CPSF metallobeta-lactamase; n=2;
           Cryptosporidium|Rep: CPSF metallobeta-lactamase -
           Cryptosporidium parvum Iowa II
          Length = 751

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 49/175 (28%), Positives = 77/175 (44%), Gaps = 30/175 (17%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW-----DEK----FDMVFIKELKRHVNS-IDAVLI 347
           GAG++    C + +I     + DCG      DE+    F ++        +N  ID V+I
Sbjct: 11  GAGQDVGRSCIIAKIGSKTVMFDCGMHMGFKDERKYPDFRLISATLDPLIINEYIDLVII 70

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD--------LYQAHKNV---- 491
           SH    H GALP+   K+G   PI  T P   +  + + D        L     NV    
Sbjct: 71  SHYHLDHCGALPFFTEKIGYKGPIVMTYPTKSVSSVLLSDCCKIMEQKLLLQKTNVDVAP 130

Query: 492 -------SEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
                  +E+  FT+ DV    +++  ++ +Q+I +     G++ITP  AGH LG
Sbjct: 131 PNETVYNNEYGFFTVSDVWSCMEKVKAIQLHQTIVIS----GIKITPYYAGHVLG 181


>UniRef50_A1RTJ6 Cluster: Beta-lactamase domain protein; n=1;
           Pyrobaculum islandicum DSM 4184|Rep: Beta-lactamase
           domain protein - Pyrobaculum islandicum (strain DSM 4184
           / JCM 9189)
          Length = 640

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 5/152 (3%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCG-----WDEKFDMVFIKELKRHVNSIDAVLISHSD 359
           L  A E      ++   E   LLDCG     +DE F ++   ++ R    +DAV+++H+ 
Sbjct: 185 LGAAMEVGRSAILVSTTESNILLDCGLKPGQYDEDFPLLDAVDIDR----LDAVVLTHAH 240

Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFD 539
             H+G LP+ + K G   P+Y T P      + + D  +  +       F+  DV+    
Sbjct: 241 MDHVGCLPF-LYKYGYRGPVYMTDPTKYQTFILLMDYIELKEREGLEPAFSRADVESVIY 299

Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             + L Y +  ++      +++T   AGH +G
Sbjct: 300 HTITLDYEEVTDI---APDVKLTFYDAGHEIG 328


>UniRef50_Q5KCZ0 Cluster: Endoribonuclease YSH1; n=2; cellular
           organisms|Rep: Endoribonuclease YSH1 - Cryptococcus
           neoformans (Filobasidiella neoformans)
          Length = 773

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 11/156 (7%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMV----FIKELKRHVNSIDAVLISHSDPL 365
           GAG+E    C V++    K + D G       +    FI EL    +++DA+LI+H    
Sbjct: 35  GAGQEVGRSCCVIEHRGKKIVCDAGLHPAQPGIGALPFIDELDW--STVDAMLITHFHVD 92

Query: 366 HLGALPYAVGKL------GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVD 527
           H  ALPY + K       G     +AT  +Y +  M    L   + + S   L+   DV 
Sbjct: 93  HAAALPYIMEKTNFKDGNGKVYMTHATKAIYGLTMMDTVRLNDQNPDTSG-RLYDEADVQ 151

Query: 528 MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            ++   + + Y+Q I + G   GLR TP  AGH LG
Sbjct: 152 SSWQSTIAVDYHQDIVIAG---GLRFTPYHAGHVLG 184


>UniRef50_UPI00015BA9DD Cluster: beta-lactamase domain protein; n=1;
           Ignicoccus hospitalis KIN4/I|Rep: beta-lactamase domain
           protein - Ignicoccus hospitalis KIN4/I
          Length = 652

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 3/158 (1%)
 Frame = +3

Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE-KFDMV--FIKELKRHVNSIDAV 341
           T+ +++  L    E      +L+  E K LLD G +   +D    F K  +  ++ +DAV
Sbjct: 179 TNYVRITALGAFKEVGRSAILLETKESKVLLDFGANVGSYDPQKHFPKVEEVPIDELDAV 238

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDD 521
           +++H+   H G +P+ + K G   P+Y T P   +  +   D  +  +   +   +T  D
Sbjct: 239 IVTHAHLDHCGLVPW-LYKYGYRGPVYVTQPTRDLMYLVQKDYIEVARKEGKPVPYTESD 297

Query: 522 VDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           ++    R + L Y    E+      +++T   AGH LG
Sbjct: 298 INSMLLRTIALNYG---EVTDVAPDIKLTFYNAGHILG 332


>UniRef50_Q0LL72 Cluster: Beta-lactamase-like; n=3; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Beta-lactamase-like -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 786

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 45/163 (27%), Positives = 72/163 (44%), Gaps = 10/163 (6%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE-----KFDMVFIKELKRHVNSIDAV 341
           +I  H   GA E    C +L++     L+D G        +     ++ LK     +DA+
Sbjct: 1   MISFHPFGGAQEVGASCGILKLGMRHILVDAGMRPAARPGQSRTPDLEALKGF--PLDAI 58

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD----LYQAH-KNVSEFDL 506
           LI+H+   H G LP  V  L  + PIYAT     + ++ + D    + Q H  +  E  L
Sbjct: 59  LITHAHIDHTGCLPL-VASLFPTVPIYATESTIALMRILLLDSARIMEQEHLAHELETPL 117

Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +    V     RI+ + ++Q +        + +T LPAGH LG
Sbjct: 118 YDQAMVTETLARIIPVAFHQELRPVAANQEISVTYLPAGHILG 160


>UniRef50_A6C193 Cluster: Exonuclease of the beta-lactamase fold
           involved in RNA processing; n=1; Planctomyces maris DSM
           8797|Rep: Exonuclease of the beta-lactamase fold
           involved in RNA processing - Planctomyces maris DSM 8797
          Length = 464

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 16/168 (9%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV---NSIDAVLIS 350
           +K+  L  AGE T   ++++ D  + LLDCG  +        +  R      S+DAV +S
Sbjct: 1   MKITFLGAAGEVTGSQHLIETDSRRILLDCGLFQGHRQESYLKNSRFAYPPESLDAVFLS 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD---------LYQAHKNVSEF- 500
           H    H G LP    K G   P++ T     + ++ + D          Y A K   +  
Sbjct: 61  HGHMDHCGNLPRLFNK-GFRGPVFCTSATADIAEIMLKDSARIQEEDARYLARKLTDKHP 119

Query: 501 ---DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
               L++ DDV     +  +L+Y +  E+   G  L++  L AGH LG
Sbjct: 120 PIEPLYSEDDVTAVAKQFERLEYQEWHEL---GDDLKVRFLDAGHILG 164


>UniRef50_Q9UKF6 Cluster: Cleavage and polyadenylation specificity
           factor subunit 3; n=53; Eumetazoa|Rep: Cleavage and
           polyadenylation specificity factor subunit 3 - Homo
           sapiens (Human)
          Length = 684

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 44/150 (29%), Positives = 70/150 (46%), Gaps = 5/150 (3%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWD---EKFDMVFIKELKRHVNSIDAVLISHSDPLH 368
           GAG+E    C +L+    K +LDCG     E  D +   +L      ID +LISH    H
Sbjct: 18  GAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAE-IDLLLISHFHLDH 76

Query: 369 LGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD-LFTLDDVDMAFDRI 545
            GALP+ + K       + T     + +  + D Y    N+S  D L+T  D++ + D+I
Sbjct: 77  CGALPWFLQKTSFKGRTFMTHATKAIYRWLLSD-YVKVSNISADDMLYTETDLEESMDKI 135

Query: 546 VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             + +++  E+     G++     AGH LG
Sbjct: 136 ETINFHEVKEV----AGIKFWCYHAGHVLG 161


>UniRef50_Q11PK2 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Cytophaga hutchinsonii ATCC 33406|Rep:
           Metallo-beta-lactamase superfamily protein - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 451

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 39/157 (24%), Positives = 77/157 (49%), Gaps = 5/157 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD--EKFDMVFIKELKRHVNSIDAVLISH 353
           +KL     A + T   Y+L+   +K L+DCG D  ++  ++         + ID V+++H
Sbjct: 1   MKLTFWGAARKVTGSMYLLESLGYKILIDCGSDFSDRHKVLTGGLFPFEASEIDLVILTH 60

Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD---LYQAHKNVSEFDLFTLDDV 524
           +   H G +P A+ + G    I +T P  ++ ++   D   + +A K ++  +    D  
Sbjct: 61  AHVDHSGNIP-ALIRAGYRGQILSTAPTAELSELLFADSAYIQRAEKKIA--NSAPSDYS 117

Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
               DR + + +N+  E+  + + +R+TP+  GH LG
Sbjct: 118 YKPVDRFIPIAFNKDFELNER-ITVRLTPV--GHILG 151


>UniRef50_Q5TA44 Cluster: Cleavage and polyadenylation specific
           factor 3-like; n=4; Eutheria|Rep: Cleavage and
           polyadenylation specific factor 3-like - Homo sapiens
           (Human)
          Length = 401

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 8/97 (8%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW------DEKF-DMVFIKELKRHVNSIDAVLISHS 356
           GAG++    C ++ I     +LDCG       D +F D  +I +  R  + +D V+ISH 
Sbjct: 22  GAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHF 81

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
              H GALPY    +G   PIY T P   +  + + D
Sbjct: 82  HLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLED 118


>UniRef50_Q8ZYD9 Cluster: MRNA 3'-end processing factor,
           conjectural; n=4; Thermoproteaceae|Rep: MRNA 3'-end
           processing factor, conjectural - Pyrobaculum aerophilum
          Length = 634

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 5/152 (3%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGW-----DEKFDMVFIKELKRHVNSIDAVLISHSD 359
           L  A E      ++   E   LLDCG      DE+F ++ + ++ R    +DAV+++H+ 
Sbjct: 179 LGAAMEVGRSAILVSTTESNVLLDCGLKPAQNDEEFPLLDLIDIDR----LDAVVLTHAH 234

Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFD 539
             H+G LP+ + K G   P+Y T P      + + D  +  +       ++  D++    
Sbjct: 235 MDHVGCLPF-LFKYGYKGPVYMTDPTKYQAFILLSDYVELKEREGLQPSYSKADIETVIY 293

Query: 540 RIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             + L Y +  ++      +++T   AGH +G
Sbjct: 294 HTITLDYEEVTDI---APDIKLTFYDAGHEIG 322


>UniRef50_Q4PEJ3 Cluster: Endoribonuclease YSH1; n=6; Fungi/Metazoa
           group|Rep: Endoribonuclease YSH1 - Ustilago maydis (Smut
           fungus)
          Length = 880

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 8/153 (5%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMV----FIKELKRHVNSIDAVLISHSDPL 365
           GAG+E    C VL+      + D G    F  +    FI EL    +++DA+LI+H    
Sbjct: 30  GAGQEVGRSCCVLKYRGKTIVCDTGVHPAFTGIAALPFIDELDW--STVDAILITHFHLD 87

Query: 366 HLGALPYAVGKLGL---SCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAF 536
           H  AL Y + K         +Y T P   + +  M D  +     ++ +LF  +++  ++
Sbjct: 88  HAAALTYIMEKTNFRDGHGKVYMTHPTKAVYRFLMSDFVRISNAGNDDNLFDENEMLASW 147

Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            +I  + ++Q + + G   GLR T   AGH LG
Sbjct: 148 RQIEAVDFHQDVSIAG---GLRFTSYHAGHVLG 177


>UniRef50_Q6CAZ0 Cluster: Yarrowia lipolytica chromosome C of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome C of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 799

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
 Frame = +3

Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGL--SCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500
           +++ VL +H++  HLGA   A        + P Y TLPV  MG++   + Y++   +S  
Sbjct: 41  TLNLVLFTHANAAHLGAYALACKLYPALAAVPAYGTLPVINMGRIATLEAYRSQGLLSS- 99

Query: 501 DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLR 602
           +  T  ++++ FD I  +KY Q I     G+G+R
Sbjct: 100 EHITATEIEIIFDNITSIKYLQPI-----GIGVR 128


>UniRef50_Q7RRQ3 Cluster: Cleavage and polyadenylation specificity
           factor, 73 kDa subunit; n=7; Plasmodium|Rep: Cleavage
           and polyadenylation specificity factor, 73 kDa subunit -
           Plasmodium yoelii yoelii
          Length = 942

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
 Frame = +3

Query: 174 SIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKEL--KRHVNSIDAVLI 347
           S I + CL GA E    C +++ ++   +LDCG    F  +    +     ++ ID  LI
Sbjct: 2   SNINIVCLGGASEVGRSCVIIESEKTSIMLDCGIHPAFMGIGCLPIYDAYDISKIDVCLI 61

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYAT 428
           +H    H GALPY + K      ++ T
Sbjct: 62  THFHMDHSGALPYLINKTRFKGRVFMT 88


>UniRef50_A6QXP5 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 925

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 8/155 (5%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDAVLISHSDP 362
           L G  E    C+++Q      +LD G     D    + F  +    ++++D +LISH   
Sbjct: 30  LGGGNEVGRSCHIIQYKGKTVMLDAGMHPAKDGFAALPFFDDFD--LSTVDILLISHFHL 87

Query: 363 LHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD----LFTLDDVDM 530
            H  +LPY + K      ++ T     + +  + D  +     S  D    L+T  D   
Sbjct: 88  DHSASLPYVLSKTNFRGRVFMTHATKAIYKWLIQDNVRVSNTSSSSDQRTTLYTEQDHLS 147

Query: 531 AFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
               I  + +N +  +      +RITP PAGH LG
Sbjct: 148 TLSHIEAIDFNTTHTIN----NIRITPFPAGHVLG 178


>UniRef50_Q8KET4 Cluster: Metallo-beta-lactamase superfamily
           protein; n=9; Bacteria|Rep: Metallo-beta-lactamase
           superfamily protein - Chlorobium tepidum
          Length = 469

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
 Frame = +3

Query: 216 TPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPY 386
           T  C++L+   +  LLDCG      + + +  +      + IDAV++SH    H G LP 
Sbjct: 13  TGSCHILRAAGYTVLLDCGLVQGSREVEALNREPFPFEPSEIDAVVLSHGHIDHSGRLPL 72

Query: 387 AVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF----------DLFTLDDVDMAF 536
            V + G   PIY      ++ ++ + D     +N + F           L+T+DD     
Sbjct: 73  LVNR-GFRGPIYTHHGTIELCEILLRDSATLSENDARFMRKHGQRDDEPLYTVDDAQRCV 131

Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSL 632
            ++  ++Y +  E+     G+ +T L AGH L
Sbjct: 132 RQMEGVRYGERREVLP---GIAVTLLDAGHIL 160


>UniRef50_Q73MR4 Cluster: Metallo-beta-lactamase family protein;
           n=1; Treponema denticola|Rep: Metallo-beta-lactamase
           family protein - Treponema denticola
          Length = 470

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRHVNS--IDAVLIS 350
           IK + L  A E T   ++L++D  K+L+DCG +  K      K    +V +  ++AV+++
Sbjct: 3   IKFYSLGAAEEVTGSKHILEVDGHKYLIDCGAFQGKRAEADKKNRDFNVPAPELEAVILT 62

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           H    H G LP  +GK G +  IYAT     +  + M D
Sbjct: 63  HGHYDHCGLLP-LLGKHGFTGNIYATPATRDIANLVMMD 100


>UniRef50_Q4N0H3 Cluster: Putative uncharacterized protein; n=2;
           Theileria|Rep: Putative uncharacterized protein -
           Theileria parva
          Length = 678

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/58 (39%), Positives = 31/58 (53%)
 Frame = +3

Query: 303 KELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ 476
           K LK   NS+D  +ISH    H+GALP+    +G S PIY T P   +  + + D  Q
Sbjct: 108 KALKNVTNSVDCSVISHFHLDHVGALPFLTEHIGYSGPIYLTYPTRALCPLLLRDSVQ 165


>UniRef50_Q236M0 Cluster: RNA-metabolising metallo-beta-lactamase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           RNA-metabolising metallo-beta-lactamase family protein -
           Tetrahymena thermophila SB210
          Length = 750

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGW----DEKFDMVFIKELKRHVNSIDAVLISHSDPL 365
           GAG+E    C +L+      + DCG     +    + +   +K   + ID + I+H    
Sbjct: 7   GAGQEVGRSCIILEYKGKTIMFDCGLHMGKNGHASLPYFDNIKP--DQIDIIFITHFHLD 64

Query: 366 HLGALPYAVGKL---GLSCPIYATLPVYKMGQMFMYD-LYQAHKNVSEFDLFTLDDVDMA 533
           H  ALPY + K    G    +YAT P   + +  + D L    +N+    L+T DD++ +
Sbjct: 65  HCAALPYFIAKTDFDGKKQKVYATSPTRAIYRHVLRDSLTDKSENIK---LYTADDIEKS 121

Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            + I  + + + +E +     ++    PAGH LG
Sbjct: 122 MEVINVIDFYEEMEHE----NIKFKCYPAGHVLG 151


>UniRef50_Q8RBU2 Cluster: Predicted exonuclease of the
           beta-lactamase fold involved in RNA processing; n=4;
           Clostridia|Rep: Predicted exonuclease of the
           beta-lactamase fold involved in RNA processing -
           Thermoanaerobacter tengcongensis
          Length = 541

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDAVLIS 350
           +K+  L  A E T  CY+++ +  +FL+DCG     E  D +  +E    +  ID VL++
Sbjct: 1   MKITFLGAAKEVTGSCYLVETENARFLVDCGMFQGGEVEDELNYQEFIFDIKDIDFVLLT 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428
           H+   H G +P  + K G    IYAT
Sbjct: 61  HAHIDHSGRIP-VLYKRGYRKRIYAT 85


>UniRef50_Q23NE4 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 747

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 30/99 (30%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
 Frame = +3

Query: 282 KFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFM 461
           KFD+ F+  + +  NSID +LI+  D + L  LP+   +  L   +YAT+PV ++GQ  +
Sbjct: 112 KFDLTFLNNIDQ--NSIDFILITSIDDIFL--LPFLFQQNKLKAKVYATVPVAQIGQHVL 167

Query: 462 YDLYQAHKNVS-EFDLFTLDDVDMAFDRIVQLKYNQSIE 575
            + Y+  +N +   DL + ++ +  + +  Q  Y Q  E
Sbjct: 168 QEYYKLVQNRNRNIDLSSSENKNGQYFQNSQNSYFQESE 206


>UniRef50_A0RXV0 Cluster: Cleavage and polyadenylation specificity
           factor/metal-dependent RNase; n=1; Cenarchaeum
           symbiosum|Rep: Cleavage and polyadenylation specificity
           factor/metal-dependent RNase - Cenarchaeum symbiosum
          Length = 645

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
 Frame = +3

Query: 174 SIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD-------EKFDMVFIKELKRHVNSI 332
           S I L  L G G+    C +L   + K L+DCG +       E +  +    +   ++ +
Sbjct: 186 SEISLTALGGFGQVGRSCMLLSTLDSKVLVDCGVNPGAAHPSESYPRLDWAGIT--LDDL 243

Query: 333 DAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFT 512
           DAV+I H+   H G LP  + K G   PIY T P   M  +   D  +         ++ 
Sbjct: 244 DAVVIGHAHLDHTGFLP-VLAKYGYRGPIYCTEPTLPMMNLIQLDAIKVATAQGRVPVYA 302

Query: 513 LDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             DV     + + L Y    ++      +++    AGH LG
Sbjct: 303 ERDVRQIMRQAITLPYGTVTDISP---DIKLVLANAGHILG 340


>UniRef50_Q1GJ92 Cluster: Beta-lactamase-like protein; n=4;
           Rhodobacteraceae|Rep: Beta-lactamase-like protein -
           Silicibacter sp. (strain TM1040)
          Length = 356

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/78 (35%), Positives = 42/78 (53%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLG 374
           LSG G++ P    L     ++LLDCG+  + +  F  +    +  +DAV ++H    H+G
Sbjct: 7   LSGIGDKGPAAMRLDTGRHRWLLDCGFGPEANATFDPD---WLIGVDAVFVTHDHIDHIG 63

Query: 375 ALPYAVGKLGLSCPIYAT 428
              YAV + GL  PIYAT
Sbjct: 64  GAAYAV-EAGL--PIYAT 78


>UniRef50_Q8SRZ4 Cluster: CLEAVAGE AND POLYADENYLATION SPECIFICITY
           FACTOR 100kDa SUBUNIT; n=1; Encephalitozoon
           cuniculi|Rep: CLEAVAGE AND POLYADENYLATION SPECIFICITY
           FACTOR 100kDa SUBUNIT - Encephalitozoon cuniculi
          Length = 639

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 32/137 (23%), Positives = 67/137 (48%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404
           C++L+ID  K L++CG     DM     +   + S DA+L++  +   +G LPY + +  
Sbjct: 20  CHMLEIDNTKILVNCGAPYAMDMSMYTPVLPQILSCDAILLTSFNINCIGGLPYVL-RNN 78

Query: 405 LSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKG 584
               +++++P+  +G++ + +  +     S  D          F+RI ++KY+Q   +  
Sbjct: 79  YYNKVFSSVPIKVLGKICLDEHLRGMGLESSVD-------TGCFERISEIKYSQPTAVN- 130

Query: 585 KGLGLRITPLPAGHSLG 635
               + I    +G+S+G
Sbjct: 131 ---NVEICAYNSGNSIG 144


>UniRef50_Q6BMW3 Cluster: Endoribonuclease YSH1; n=2;
           Saccharomycetaceae|Rep: Endoribonuclease YSH1 -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 815

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 20/175 (11%)
 Frame = +3

Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFD----MVFIKELKRHVNSIDA 338
           T   K   L G  E    C++++      +LD G          + F  E    ++ +D 
Sbjct: 11  TDDFKFFGLGGCNEVGRSCHIIEYKNKVIMLDAGVHPGLQGLSSLPFYDEYD--LSKVDI 68

Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIY---ATLPVYKM-------------GQMFMYDL 470
           +L+SH    H  +LPY +     +  ++   AT  +Y+              G     + 
Sbjct: 69  LLVSHFHLDHAASLPYVMQHTNFNGRVFMTHATKAIYRWLLSDFVKVTSIGGGSDARLNN 128

Query: 471 YQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
              + N    +L+T DD+  +FDRI  + Y+ +IE+     G+R T   AGH LG
Sbjct: 129 SDPNANTGSSNLYTDDDLMRSFDRIETIDYHSTIELD----GIRFTAYHAGHVLG 179


>UniRef50_A5KD85 Cluster: Cleavage and polyadenylation specifity
           factor protein, putative; n=2; Plasmodium vivax|Rep:
           Cleavage and polyadenylation specifity factor protein,
           putative - Plasmodium vivax
          Length = 858

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKEL--KRHVNSIDAVLISH 353
           I + CL GA E    C +++      +LDCG    F  +    +     ++ +D  LI+H
Sbjct: 4   INIVCLGGASEVGRSCVIIESANRSIMLDCGIHPAFMGIGCLPIYDAYDISKVDLCLITH 63

Query: 354 SDPLHLGALPYAVGKLGLSCPIYAT 428
               H GALPY V +      +Y T
Sbjct: 64  FHMDHSGALPYLVNRTRFKGKVYMT 88


>UniRef50_Q3ZY44 Cluster: Metallo-beta-lactamase family protein;
           n=3; Dehalococcoides|Rep: Metallo-beta-lactamase family
           protein - Dehalococcoides sp. (strain CBDB1)
          Length = 468

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISH 353
           IK+  L  A   T   Y+LQ D  + L+DCG  ++  +         V   S++AVL+SH
Sbjct: 3   IKIQFLGAAQNVTGSRYLLQTDHTRLLVDCGLYQERHLQNRNWQPFDVPPESLNAVLVSH 62

Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           +   H G LP  V K G + P+Y T    ++ ++ + D
Sbjct: 63  AHIDHCGLLPKLV-KDGYNGPVYLTAATAEIARISLAD 99


>UniRef50_Q2YZG4 Cluster: Predicted exonuclease of the
           beta-lactamase fold involved in RNA processing; n=1;
           uncultured gamma proteobacterium|Rep: Predicted
           exonuclease of the beta-lactamase fold involved in RNA
           processing - uncultured gamma proteobacterium
          Length = 426

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 16/119 (13%)
 Frame = +3

Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD- 503
           ++DA+L+SH+   H G +P  V K G   P+YAT P   + Q+ + D   AH    + D 
Sbjct: 14  TVDAMLVSHAHMDHSGNIPNLV-KKGFKGPVYATPPTVDLCQLMLRD--SAHLQKKDIDW 70

Query: 504 ---------------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
                          L+++DD + +      ++Y++S E+     G+++T   AGH LG
Sbjct: 71  VNRIRAKHHQPPMEPLYSMDDAEESLHYFQPVEYDKSFEVIP---GVQVTFKEAGHILG 126


>UniRef50_Q7UMQ3 Cluster: Cleavage and polyadenylation specifity
           factor-related protein; n=1; Pirellula sp.|Rep: Cleavage
           and polyadenylation specifity factor-related protein -
           Rhodopirellula baltica
          Length = 488

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 46/160 (28%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEE-TPPCYVLQIDEFKFLL-DCGWDEKFDMVFIK--ELKRHVNSID 335
           + S++KL    GA E  T  C+ L ID+ + LL DCG  +  D       E++  +  I 
Sbjct: 41  LMSLMKL-VHHGAHEGVTGSCHQLWIDDSQSLLVDCGTFQGEDARKKPNPEIEFSLRGIQ 99

Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515
           A+L++H    H G +PY +   G   PI  + P  K+  + M D  +     +       
Sbjct: 100 ALLLTHVHIDHAGRIPYLLA-AGFDHPILCSAPTAKLLPLVMEDALKI--GFTRSKRLIK 156

Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             +      +V L Y+Q  +  G   G+++  LPAGH LG
Sbjct: 157 KFLGQIRKLLVPLPYHQWHDCPG---GVKVRLLPAGHVLG 193


>UniRef50_Q15V20 Cluster: RNA-metabolising metallo-beta-lactamase;
           n=1; Pseudoalteromonas atlantica T6c|Rep:
           RNA-metabolising metallo-beta-lactamase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 467

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
 Frame = +3

Query: 201 GAGEE-TPPCYVLQIDEF-KFLLDCGWDE---KFDMVFIKELKRHVNSIDAVLISHSDPL 365
           GA +E T  C++++   F K LLDCG  +     D +  +    +  SIDAVL+SH+   
Sbjct: 8   GAAQEVTGSCHLIESASFGKILLDCGMHQGGSSIDRIGDEGFPFNPASIDAVLLSHAHLD 67

Query: 366 HLGALPYAVGKLGLSCPIYAT 428
           H G LP  V   G + PIY T
Sbjct: 68  HSGMLPKLVHD-GFTGPIYCT 87


>UniRef50_Q8TW11 Cluster: Predicted metal-dependent RNase, consists
           of a metallo-beta-lactamase domain and an RNA-binding KH
           domain; n=1; Methanopyrus kandleri|Rep: Predicted
           metal-dependent RNase, consists of a
           metallo-beta-lactamase domain and an RNA-binding KH
           domain - Methanopyrus kandleri
          Length = 652

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 8/159 (5%)
 Frame = +3

Query: 183 KLHCLSGAGEETPPCYVLQIDEFKFLLDCGWD------EKFDMVFIKELKRHVNSIDAVL 344
           ++  L G  E       L  +E + LLDCG +      + +    + E +  ++ +DA++
Sbjct: 195 RVSALGGFQEVGRSSLFLHTEESRVLLDCGVNVAANGTDAYPHFNVPEFR--MDDLDAIV 252

Query: 345 ISHSDPLHLGALPYAVGK--LGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLD 518
           I+H+   H G LPY      +    P+Y T P   +  + + D  +  +   +   +T  
Sbjct: 253 ITHAHLDHCGFLPYFYRHKVIESRVPVYCTPPTRDLMYLLLTDYIKVLEKRGQEPPYTEK 312

Query: 519 DVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           DV     R + + Y +  ++      + IT   AGH LG
Sbjct: 313 DVKKVIKRTITIDYREPTDITP---DMSITFYNAGHILG 348


>UniRef50_A5KKJ4 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus torques ATCC 27756|Rep: Putative
           uncharacterized protein - Ruminococcus torques ATCC
           27756
          Length = 534

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 32/108 (29%), Positives = 49/108 (45%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359
           +KL  +  A E T  C+ LQ      L+DCG ++  D+     L    N ID V ++H+ 
Sbjct: 1   MKLTFVGAAHEVTGSCHFLQAAGKNILIDCGMEQGPDLYENPGLPIPENEIDYVFLTHAH 60

Query: 360 PLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503
             H G LP  + K G    I+ T     +  + + D   AH  + EF+
Sbjct: 61  IDHSGMLP-KLAKNGFKGQIFTTFATADLCNIMLRD--SAH--IQEFE 103


>UniRef50_A3I563 Cluster: Zn-dependent hydrolase, beta-lactamase
           superfamily protein; n=1; Bacillus sp. B14905|Rep:
           Zn-dependent hydrolase, beta-lactamase superfamily
           protein - Bacillus sp. B14905
          Length = 356

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 24/69 (34%), Positives = 32/69 (46%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356
           + K+  L G GE    C+ ++      LLDCG  +            HV  + AV ISHS
Sbjct: 1   MFKIEILGGVGEYGRNCFYIENQGKAILLDCGVMKNSQKTPPAITLNHVEKLKAVFISHS 60

Query: 357 DPLHLGALP 383
              H+GALP
Sbjct: 61  HIDHVGALP 69


>UniRef50_Q9UXE8 Cluster: MRNA 3'-end polyadenylation factor; n=6;
           Thermoprotei|Rep: MRNA 3'-end polyadenylation factor -
           Sulfolobus solfataricus
          Length = 639

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 8/160 (5%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-------WDEK-FDMVFIKELKRHVNSID 335
           +++  L G  E      +++  E K LLD G       + EK F  + I +LK  +  +D
Sbjct: 183 VRITALGGFLEVGRSAVLVETPESKVLLDVGLNPSANMFGEKLFPKLDIDQLK--MEELD 240

Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515
           AV+I+H+   H G +P+ + K G   P+Y T+P   +  +   D     +   +   ++ 
Sbjct: 241 AVVITHAHLDHCGMVPF-LFKYGYEGPVYTTVPTRDIMALMQLDSLDVAEKEGKPIPYSA 299

Query: 516 DDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            +V       + L Y +  ++      +R+T   AGH LG
Sbjct: 300 KEVRKELLHTITLDYGEVTDI---APDIRLTFYNAGHILG 336


>UniRef50_Q5CPX2 Cluster: Cleavage and polyadenylation specifity
           factor protein, CPSF metallobeta-lactamase; n=2;
           Cryptosporidium|Rep: Cleavage and polyadenylation
           specifity factor protein, CPSF metallobeta-lactamase -
           Cryptosporidium parvum Iowa II
          Length = 780

 Score = 42.3 bits (95), Expect = 0.009
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 14/159 (8%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWDEKFDMVFIKEL--KRHVNSIDAVLISHSDPLHL 371
           GAG E    C V+       + DCG    F  +    +     V++ID  LI+H    H 
Sbjct: 30  GAGCEVGRSCVVVSFKGRSVMFDCGIHPAFSGIGSLPVFDAIDVSTIDLCLITHFHLDHS 89

Query: 372 GALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK-----------NVSEFDLFTLD 518
           GA PY V     +  ++ T P   + ++   D  + +K            +S  +L+T  
Sbjct: 90  GATPYFVSLTDFNGKVFMTEPTKAICKLVWQDYARVNKFSAGSIESEEAPLSSINLYTEK 149

Query: 519 DVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           D++ A +    + + Q +E+     G+R +   AGH LG
Sbjct: 150 DIEKAINMTEIIDFRQQVELD----GIRFSCYGAGHVLG 184


>UniRef50_Q97AZ6 Cluster: Cleavage and polyadenylation specificity
           factor; n=9; Euryarchaeota|Rep: Cleavage and
           polyadenylation specificity factor - Thermoplasma
           volcanium
          Length = 639

 Score = 42.3 bits (95), Expect = 0.009
 Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 10/162 (6%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG----------WDEKFDMVFIKELKRHVNS 329
           ++L  L G  E      ++     K L+DCG          WD     +++ E++  ++S
Sbjct: 180 VRLTALGGHSEVGRSATLVSTKNSKVLIDCGMMNVGPDADPWDAA-PYLYVPEVQP-LSS 237

Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509
           IDAV+++H+   H G LP  + K G   P+Y T P   +  +   D  +  +       +
Sbjct: 238 IDAVILTHAHLDHSGLLP-LLFKYGYDGPVYMTQPTRDLAVLLQDDYIKVARMEGGKVPY 296

Query: 510 TLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
               +       + L+Y ++ ++      +R+T   AGH LG
Sbjct: 297 ESKYIREELKHTITLRYGETTDIT---RDMRLTFYNAGHILG 335


>UniRef50_Q9RZ85 Cluster: Cleavage and polyadenylation specificity
           factor-related protein; n=2; Deinococcus|Rep: Cleavage
           and polyadenylation specificity factor-related protein -
           Deinococcus radiodurans
          Length = 499

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 44/175 (25%), Positives = 79/175 (45%), Gaps = 20/175 (11%)
 Frame = +3

Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAV 341
           T  +++     A   T   ++L +     L+DCG  +  D +  +  +       S+DAV
Sbjct: 11  TLAMQMQSFGAACTVTGSMHLLTLGGRHLLVDCGLFQGGDELERRNRESFPFEPASLDAV 70

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQM------------FMYDLYQAHK 485
           L++H+   H+G LP  V +LG   P+Y T P   + +             +  DL +A +
Sbjct: 71  LLTHAHLDHVGRLPLLV-RLGYRGPVYCTPPTAALAETVLLDSARLQVEGYRQDLRRARR 129

Query: 486 NVSEFD----LFTLDDVDMAFDRI-VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
              E +    L+  +DV      +  QL++ +++ + G    +R+TP  AGH LG
Sbjct: 130 QGREDEVPPPLYDEEDVHRTLALLRPQLEFGETVTVAG----VRVTPQRAGHILG 180


>UniRef50_Q6MLH4 Cluster: Predicted exonuclease of the
           beta-lactamase family; n=2; Proteobacteria|Rep:
           Predicted exonuclease of the beta-lactamase family -
           Bdellovibrio bacteriovorus
          Length = 452

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFI---KELKRHVNSIDAVLISHSDPL 365
           L  AG  T   +++  ++ + L+DCG  + F  +     ++       I AV+++H+   
Sbjct: 6   LGAAGTVTGSKFLVHNNDTRILVDCGMFQGFKELRELNWEDFPFDPRDIQAVVLTHAHLD 65

Query: 366 HLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           H GALP  V K G   PIY T P  ++ ++ + D
Sbjct: 66  HCGALPLLV-KKGFKGPIYCTEPTLELTKIILLD 98


>UniRef50_A7QCN8 Cluster: Chromosome chr12 scaffold_78, whole genome
           shotgun sequence; n=12; Eukaryota|Rep: Chromosome chr12
           scaffold_78, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 662

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 26/104 (25%), Positives = 51/104 (49%)
 Frame = +3

Query: 324 NSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503
           ++ID +L++H    H  +LPY + K      ++ T     + ++ + D  +  K   E  
Sbjct: 42  STIDVLLVTHFHLDHAASLPYFLEKTTFKGRVFMTHATKAIYKLLLSDYVKVSKVSVEDM 101

Query: 504 LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           L+   D+  + D+I  + ++Q++E+     G+R     AGH LG
Sbjct: 102 LYDEQDILRSMDKIEVIDFHQTLEVN----GIRFWCYTAGHVLG 141


>UniRef50_Q7QYP3 Cluster: GLP_393_23867_26140; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_393_23867_26140 - Giardia lamblia
           ATCC 50803
          Length = 757

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 48/178 (26%), Positives = 81/178 (45%), Gaps = 26/178 (14%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEF----KFLLDCGW----DEKFDMVFIK-----ELKRH 320
           +KL  L    E    C++L           +LDCG      E  D V I+     +L+ +
Sbjct: 29  VKLTPLGAGNEVGRSCFILSYQRSGCSGSIMLDCGLHPALSETRDYVAIQALPFFDLEDY 88

Query: 321 VNSIDAVLISHSDPLHLGALPYAV----------GK--LGLSCPIYATLPVYKMGQMFMY 464
           V+++  +LI+H    H+ ALPY +          GK  L    P+Y T P  K+ +  + 
Sbjct: 89  VSTLSLILITHFHNDHIAALPYLLRCLRDRAVKEGKPELHYIPPVYMTAPTLKIFKESVT 148

Query: 465 DLYQAHKNVSEFDLFTLDDVD-MAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           D+      +S+  L+T +DV+ MA +  +   + Q+  +     G+  T +PAGH +G
Sbjct: 149 DV------ISQTKLYTHEDVEFMAKNTKLLTSFYQTERVN----GISFTAMPAGHVIG 196


>UniRef50_A7AWH8 Cluster: RNA-metabolising metallo-beta-lactamase
           and metallo-beta-lactamase superfamily domain containing
           protein; n=1; Babesia bovis|Rep: RNA-metabolising
           metallo-beta-lactamase and metallo-beta-lactamase
           superfamily domain containing protein - Babesia bovis
          Length = 760

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 20/58 (34%), Positives = 30/58 (51%)
 Frame = +3

Query: 303 KELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQ 476
           K L    ++ID  +ISH    H+GALP+    LG   P++ T P   +G + + D  Q
Sbjct: 112 KSLNDITSNIDCAIISHFHLDHIGALPFLTEHLGYKGPVFMTYPTRGLGPIMLRDSAQ 169


>UniRef50_Q60355 Cluster: Uncharacterized protein MJ0047; n=6;
           Methanococcales|Rep: Uncharacterized protein MJ0047 -
           Methanococcus jannaschii
          Length = 428

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 29/113 (25%), Positives = 52/113 (46%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404
           C  ++ D+ K LLDCG     ++ +   L   +  +D V ISH+   H GALP    +  
Sbjct: 16  CIEIKTDKSKILLDCGVKLGKEIEY-PILDNSIRDVDKVFISHAHLDHSGALPVLFHR-K 73

Query: 405 LSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYN 563
           +  P+  T    K+ ++ + D+ +  +  ++   +   DV  A    + L YN
Sbjct: 74  MDVPVITTELSKKLIKVLLKDMVKIAETENKKIPYNNHDVKEAIRHTIPLNYN 126


>UniRef50_UPI00004992E1 Cluster: cleavage and polyadenylation
           specificity factor subunit, putative; n=1; Entamoeba
           histolytica HM-1:IMSS|Rep: cleavage and polyadenylation
           specificity factor subunit, putative - Entamoeba
           histolytica HM-1:IMSS
          Length = 452

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 2/154 (1%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE-KFDM-VFIKELKRHVNSIDAVLISH 353
           +K+H   G       C V++  E   L DCG++  + D+ +    +    + I A+ I+H
Sbjct: 1   MKVHVFGGGKSVGSSCVVVEGKEDAILFDCGYNPVRPDVGIDFSRMNAISSKIRAICITH 60

Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMA 533
               H+G LP+ + K  +  PIY + P   +  + + D++  +      +LF   D D  
Sbjct: 61  FHVDHVGMLPW-LTKF-MDVPIYLSEPTQALLSLIINDIHSGN------NLFCQADFDKC 112

Query: 534 FDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
              I+Q K       K     L I  + AGH+LG
Sbjct: 113 ---ILQCKPIDPTMTKRVTQNLSIRCIYAGHALG 143


>UniRef50_Q3AAG6 Cluster: Metallo-beta-lactamase family protein;
           n=2; Carboxydothermus hydrogenoformans|Rep:
           Metallo-beta-lactamase family protein - Carboxydothermus
           hydrogenoformans (strain Z-2901 / DSM 6008)
          Length = 504

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 14/166 (8%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIK---ELKRHVNSIDAVLIS 350
           ++L     A   T  CY+  +   KFL+DCG  +    +  +   E   +   I+ +L++
Sbjct: 1   MELTFFGAADTVTGSCYLFNVAGHKFLVDCGLFQGPKAIKERNYGEFPFNPREIEFILLT 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD--------LYQAHKNVSEFDL 506
           H+   H G +P  V K G    IYAT P   +  + + D        + + ++ +     
Sbjct: 61  HAHIDHSGLIPKLV-KKGFKGTIYATEPTVDLAAVMLPDSGHVQEMEVERKNRKLRRAGK 119

Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGL---GLRITPLPAGHSLG 635
             L  +  A D    L Y Q I ++       GL +T   AGH LG
Sbjct: 120 PELQPIYTADDAFNALAYFQKIPLETPITPLPGLEVTFFDAGHILG 165


>UniRef50_A3WMD7 Cluster: Predicted exonuclease of the
           beta-lactamase fold; n=1; Idiomarina baltica OS145|Rep:
           Predicted exonuclease of the beta-lactamase fold -
           Idiomarina baltica OS145
          Length = 460

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQID-EFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356
           I L  L G  + T  C++  ++ +   ++DCG  +             V+S+ AV I+H+
Sbjct: 10  IHLTHLGGTWQVTGSCHLWHLNAQQTVMIDCGAFQGITQEDDLTPYVDVDSLAAVFITHA 69

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAF 536
              H+G LP  +  LG   PIY T     + Q+ + D  Q    + +    T  +  +A 
Sbjct: 70  HLDHVGRLPQLLA-LGYRGPIYCTAATLALMQLVLGDSLQL-AGIRDESALTAFNTLLA- 126

Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             +V  +Y Q++++      L +T   AGH LG
Sbjct: 127 RHVVLCEYGQTVDVLP---SLSVTFEEAGHILG 156


>UniRef50_Q0HMU8 Cluster: RNA-metabolizing metallo-beta-lactamase;
           n=16; Shewanella|Rep: RNA-metabolizing
           metallo-beta-lactamase - Shewanella sp. (strain MR-4)
          Length = 480

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 51/163 (31%), Positives = 73/163 (44%), Gaps = 18/163 (11%)
 Frame = +3

Query: 201 GAGEE-TPPCYVLQIDEFKFLLDCGWDE--KFDMVFIKE-LKRHVNSIDAVLISHSDPLH 368
           GA EE T  C++L I   + LLDCG  +  K D +   E       +I AV++SH+   H
Sbjct: 9   GATEEVTGSCHLLTIAGQQMLLDCGLIQGGKADELRNHERFSFDPQAISAVVLSHAHIDH 68

Query: 369 LGALPYAVGKLGLSCPIY-----ATLPVYKMGQMFMYDLYQAHKN-----VSEFD----L 506
            G LP  V K G + PIY     A L    +    M  +    +N       E +    L
Sbjct: 69  SGRLPLLV-KAGYTGPIYTHKATAELCAIMLKDAAMLQVRDTERNNKKRAKHELEPLEPL 127

Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           FT++D + A  + V L+Y Q  ++      + I    AGH LG
Sbjct: 128 FTVEDAEQAVTQFVALEYGQVTQVIPH---VDICLSDAGHILG 167


>UniRef50_Q0EST3 Cluster: Beta-lactamase-like; n=2;
           Thermoanaerobacter ethanolicus|Rep: Beta-lactamase-like
           - Thermoanaerobacter ethanolicus X514
          Length = 616

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%)
 Frame = +3

Query: 228 YVLQIDEFKFLLDCGWDEKFDMVF---IKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398
           Y++  +    LLD G   K   ++   IK L   +  ID V+I+H    H G +   + K
Sbjct: 218 YLVSYEGINILLDAGALIKDKTLYYNSIKNLPIDIKDIDLVIITHVHLDHSGGIVELLRK 277

Query: 399 LGLSCPIYATLPVYK-MGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIE 575
            GL+ PI  + P  + + Q+F+    +    + E ++   D   ++FD     +   S  
Sbjct: 278 -GLNSPIIISRPTKEILKQIFLRGHTKLEVKIEE-EIINFDSQIISFD----TEEESSFR 331

Query: 576 MKGKGLGLRITPLPAGHSLG 635
           +K K + L++   PAGH LG
Sbjct: 332 IKNKEVKLKL--FPAGHILG 349


>UniRef50_Q023M0 Cluster: Beta-lactamase domain protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Beta-lactamase domain
           protein - Solibacter usitatus (strain Ellin6076)
          Length = 469

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDE---KFDMVFIKELKRHVNSIDAVLIS 350
           +KL     AG  T   ++++    ++LLDCG  +   K      + L    +SIDAV++S
Sbjct: 1   MKLTFWGAAGTVTGSMHLVETGGKRYLLDCGLAQGRRKEADAKNRNLPFSGSSIDAVVLS 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428
           H+   H G LP  V K G S PIY+T
Sbjct: 61  HAHIDHSGNLPSLV-KHGFSGPIYST 85


>UniRef50_A7HPZ1 Cluster: Beta-lactamase domain protein; n=2;
           Alphaproteobacteria|Rep: Beta-lactamase domain protein -
           Parvibaculum lavamentivorans DS-1
          Length = 472

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 18/168 (10%)
 Frame = +3

Query: 186 LHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELK-----RHVNSIDAVLIS 350
           L  L GAG  T   ++L +D  + L+DCG  +   +  ++EL          SIDA++++
Sbjct: 24  LTSLGGAGTVTGSKHLLTLDGHRILIDCGLFQ--GLKNLRELNWAPFPVDPRSIDAIVLT 81

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL---------YQAHKNVSE-- 497
           H+   H G LP  V + G    ++AT     +  + + D          Y   K+ S+  
Sbjct: 82  HAHLDHSGYLPKIV-REGFRGRVFATDTTCNVAALILKDSGYIQEKDADYANRKSYSKHK 140

Query: 498 --FDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
               L+ + D + A +    + Y++++ + G   G  +T   AGH LG
Sbjct: 141 PALPLYGVRDAERAVEAFTAVPYHKTVSLPG---GATLTFRHAGHILG 185


>UniRef50_A6FNJ5 Cluster: Beta-lactamase-like protein; n=1;
           Roseobacter sp. AzwK-3b|Rep: Beta-lactamase-like protein
           - Roseobacter sp. AzwK-3b
          Length = 245

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +3

Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380
           G+G     C+ +  +E +FL+DCG      M+ +K ++    +ID + I+H    H G L
Sbjct: 13  GSGGRFNTCFHVATEETRFLIDCGASS---MIALKAMQIDRAAIDTIFITHFHGDHFGGL 69

Query: 381 PY 386
           PY
Sbjct: 70  PY 71


>UniRef50_A0JWK6 Cluster: Beta-lactamase domain protein; n=2;
           Bacteria|Rep: Beta-lactamase domain protein -
           Arthrobacter sp. (strain FB24)
          Length = 461

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 39/167 (23%), Positives = 76/167 (45%), Gaps = 16/167 (9%)
 Frame = +3

Query: 183 KLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLISH 353
           +L  L      T   Y+++    + L+DCG  + + ++  +         +SIDA+L++H
Sbjct: 8   QLRFLGATDSVTGSRYLVEAAGKRILVDCGLFQGYKVLRDRNRIPFPVRPDSIDAILLTH 67

Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF----------- 500
           +   H G +P A+ + G + P+YAT    ++  + + D     +  +++           
Sbjct: 68  AHLDHTGYVP-ALVRDGFNGPVYATEGTTELCTLLLPDSGHLQEEEAKYAYEHGSSRHSP 126

Query: 501 --DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
              L+T  D   + D   +  ++  +E+ G   G+  T LPAGH LG
Sbjct: 127 PVPLYTAADAVRSLDSFREHGFDTPLELGG---GIAATFLPAGHILG 170


>UniRef50_Q2RJ88 Cluster: RNA-metabolising metallo-beta-lactamase;
           n=5; Bacteria|Rep: RNA-metabolising
           metallo-beta-lactamase - Moorella thermoacetica (strain
           ATCC 39073)
          Length = 536

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 25/100 (25%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLI 347
           +IKL     AG  T  CY+L    ++ L+DCG  +    +  +       +  +IDA+++
Sbjct: 1   MIKLQFCGAAGTVTGSCYLLDTGRYRLLIDCGLFQGSKAIKERNYGPFPFNPGAIDALIL 60

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           +H+   H G +P  +   G   PI+ T    ++ ++ + D
Sbjct: 61  THAHIDHCGLIP-KLYLQGFKGPIFTTPVTAELARVLLPD 99


>UniRef50_A5URN4 Cluster: Beta-lactamase domain protein; n=5;
           Chloroflexi (class)|Rep: Beta-lactamase domain protein -
           Roseiflexus sp. RS-1
          Length = 561

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 8/86 (9%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCG--WDEK----FDMVF--IKELKRHVNSIDAVLIS 350
           L GAGE     +VL+ ++   +LDCG  + E      D+V   I  L+   + I A++++
Sbjct: 11  LGGAGEVGRNMWVLEQNDEILVLDCGVMFPEADMLGVDLVLPDITYLRDQKDKIKAIVLT 70

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428
           H    H+GA+PY V +L    PIY T
Sbjct: 71  HGHEDHIGAVPYLVPELDFP-PIYGT 95


>UniRef50_Q4AMZ9 Cluster: Beta-lactamase-like:RNA-metabolising
           metallo-beta-lactamase; n=2; Chlorobium|Rep:
           Beta-lactamase-like:RNA-metabolising
           metallo-beta-lactamase - Chlorobium phaeobacteroides BS1
          Length = 462

 Score = 40.3 bits (90), Expect = 0.038
 Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 17/157 (10%)
 Frame = +3

Query: 216 TPPCYVLQIDEFKFLLDCG---WDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPY 386
           T  C++L+ID  + LLDCG     E+ + +  +        IDAV++SH    H G +P 
Sbjct: 13  TGSCHILRIDGRRILLDCGLVQGREEEEALNREPFPFDPREIDAVVLSHGHIDHSGRVPL 72

Query: 387 AVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD--------------LFTLDDV 524
            V K G   P+Y       +  + + D  + ++    ++              L+T++DV
Sbjct: 73  LV-KKGFDGPVYTHPATRDLALVLLQDSARLNERDVRYENRLRERKNMPLIEPLYTVEDV 131

Query: 525 DMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
               + +  LKY    E+     G+ I    AGH LG
Sbjct: 132 VRTVNLMQGLKYGVKKEILP---GVTIRFQDAGHILG 165


>UniRef50_A5N0B8 Cluster: Putative uncharacterized protein; n=1;
           Clostridium kluyveri DSM 555|Rep: Putative
           uncharacterized protein - Clostridium kluyveri DSM 555
          Length = 280

 Score = 40.3 bits (90), Expect = 0.038
 Identities = 38/128 (29%), Positives = 64/128 (50%), Gaps = 2/128 (1%)
 Frame = +3

Query: 258 LLDCGWDEKFDMVF--IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATL 431
           L+D G  + ++ +F  IKE  R ++ I+ V++SHS P H+G+      K    C + A  
Sbjct: 40  LIDTGVKDSYEKIFSYIKEQGRSIDEINLVILSHSHPDHIGSANKI--KTITGCKVMA-- 95

Query: 432 PVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITP 611
             +K  Q ++ DL   +K+      + L +  +  D +V  K  Q I++  + L L+I  
Sbjct: 96  --HKGEQEWIEDLSVQYKSRMVPGFYELVNKSVKVDELV--KDKQEIKL-DEDLTLQIIH 150

Query: 612 LPAGHSLG 635
            P GHS G
Sbjct: 151 SP-GHSKG 157


>UniRef50_Q11BH9 Cluster: Beta-lactamase-like; n=6;
           Proteobacteria|Rep: Beta-lactamase-like - Mesorhizobium
           sp. (strain BNC1)
          Length = 452

 Score = 39.9 bits (89), Expect = 0.050
 Identities = 44/171 (25%), Positives = 79/171 (46%), Gaps = 18/171 (10%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV-----NSIDAV 341
           ++ L  L GAG  T   ++L   + + L+DCG  +   +  ++EL         +SIDAV
Sbjct: 1   MLTLTSLGGAGTVTGSKHLLTNGDRRILIDCGLFQ--GLKNLRELNWEPLPVAPSSIDAV 58

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL---------YQAHKNVS 494
           +++H+   H G LP  V + G    IYAT     + ++ + D          Y   K  S
Sbjct: 59  VLTHAHLDHSGYLPKLV-RDGFKGRIYATAATRDVAELILKDSGFLNEKDAEYANRKGFS 117

Query: 495 E----FDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           +      L+ + D + A +    + +++++++ G   G  +T   AGH LG
Sbjct: 118 KHKPALPLYGVRDAERAMEFFSIVPFDKAVQLPG---GATLTFRHAGHILG 165


>UniRef50_Q011B3 Cluster: Putative metallo beta subunit lactamase;
           n=1; Ostreococcus tauri|Rep: Putative metallo beta
           subunit lactamase - Ostreococcus tauri
          Length = 404

 Score = 39.9 bits (89), Expect = 0.050
 Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
 Frame = +3

Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKM--GQMFMYDLYQAH 482
           L R  + I+AVLI+H    H+GALP+ +  L  + PIYA L   ++   +M  Y L+   
Sbjct: 44  LHRWRDKIEAVLITHGHEDHIGALPWVIPALDPATPIYAGLFTMQLIKRRMLEYSLW--- 100

Query: 483 KNVSEFDLFTLDD 521
            N   F +F +++
Sbjct: 101 -NDDRFKVFNMNE 112


>UniRef50_Q5WCW7 Cluster: Beta-lactamase superfamily Zn-dependent
           hydrolase; n=1; Bacillus clausii KSM-K16|Rep:
           Beta-lactamase superfamily Zn-dependent hydrolase -
           Bacillus clausii (strain KSM-K16)
          Length = 367

 Score = 39.5 bits (88), Expect = 0.066
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFK--FLLDCGWDEKFDMVFIKELKRHVNSIDAVLIS 350
           ++K+  L G GE    C++L+ +      LLDCG        F    ++  ++ID V +S
Sbjct: 1   MVKVTALGGVGEYGRNCFLLKEEATNQTILLDCGVKNGKPEQFPAITEQLASTIDVVFLS 60

Query: 351 HSDPLHLGALPYAVGK 398
           H    H+GALP    K
Sbjct: 61  HVHNDHVGALPLLAAK 76


>UniRef50_Q3LWF4 Cluster: Ysh1 3' mRNA end processing factor; n=1;
           Bigelowiella natans|Rep: Ysh1 3' mRNA end processing
           factor - Bigelowiella natans (Pedinomonas minutissima)
           (Chlorarachnion sp.(strain CCMP 621))
          Length = 544

 Score = 39.5 bits (88), Expect = 0.066
 Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 13/167 (7%)
 Frame = +3

Query: 174 SIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-------WDEKFDMVFIKELKRHVNSI 332
           SI+K+  L G  +    C  + I    F+LD G       W     + F+K++ + +N  
Sbjct: 5   SIVKILQLGGTFQIGNSCIYVMIKNTIFILDIGIIRSDKYWMHLESINFLKKITKPLN-- 62

Query: 333 DAVLISHSDPLHLGALP----YAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500
              LISH    H+G+LP    Y   K+        +   Y    +F Y+  +      + 
Sbjct: 63  --FLISHYHLDHIGSLPLILNYGSDKVFFLLK-NLSYSTYLTKLLFFYNSKEFLNFTDKL 119

Query: 501 DL--FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
            +  F  DD++M  + I+ +K N    ++G  +    T   +GHSLG
Sbjct: 120 KIKSFNQDDIEMVMELIISVKENTVKMLRGNNIA---TFFNSGHSLG 163


>UniRef50_Q92EY9 Cluster: Lin0319 protein; n=39; Bacilli|Rep:
           Lin0319 protein - Listeria innocua
          Length = 276

 Score = 39.1 bits (87), Expect = 0.088
 Identities = 26/95 (27%), Positives = 45/95 (47%)
 Frame = +3

Query: 231 VLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLS 410
           +++  + K L+DCG   K       ++ R +N +DA+LI+H    H+  L     K  L 
Sbjct: 30  LVETGDQKILIDCGLSGKKMEGLFAQVGRDMNDLDAILITHEHSDHIKGLGVLARKYKL- 88

Query: 411 CPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515
            PIYA    +K     + ++    K   +FD+ T+
Sbjct: 89  -PIYANAKTWKAMDNMIGEVSSEQK--FQFDMETV 120


>UniRef50_Q2NK28 Cluster: Zn-dependent hydrolase; n=2; Candidatus
           Phytoplasma asteris|Rep: Zn-dependent hydrolase - Aster
           yellows witches'-broom phytoplasma (strain AYWB)
          Length = 574

 Score = 39.1 bits (87), Expect = 0.088
 Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 10/132 (7%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVF--------IKELKRHVNSID 335
           IK   L G GE     YVLQI++  FLLD G       ++          +L+   + I 
Sbjct: 16  IKFFALGGLGESGKNFYVLQINDSYFLLDAGLKYPNTNLYGIDSMIADYYKLQDIKDKIK 75

Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK-NVSEFDL-F 509
            V +S +   +LGALPY +    +  P+YA+   + M  +  +  +Q+HK N   F+L  
Sbjct: 76  GVFLSSAFETNLGALPYLMKDFDI--PVYAS--YFTMQVLKAH--FQSHKINYRNFNLQI 129

Query: 510 TLDDVDMAFDRI 545
              D  + FD +
Sbjct: 130 VKSDERLIFDDV 141


>UniRef50_O87142 Cluster: WbfZ protein; n=32; Vibrionaceae|Rep: WbfZ
           protein - Vibrio cholerae
          Length = 446

 Score = 39.1 bits (87), Expect = 0.088
 Identities = 23/89 (25%), Positives = 44/89 (49%)
 Frame = +3

Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380
           G    T  C+ L+ D    L+DCG  +  D   +  ++  +  +DA++++H+   H+G L
Sbjct: 16  GKASVTGSCHELRADGQALLIDCGLFQGADERPLA-VEFALGHVDALILTHAHIDHIGRL 74

Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           P+ +   G   PIY T    ++  + + D
Sbjct: 75  PWLLA-AGFKQPIYCTAATAELVPLMLED 102


>UniRef50_A7CRQ7 Cluster: Beta-lactamase domain protein; n=1;
           Opitutaceae bacterium TAV2|Rep: Beta-lactamase domain
           protein - Opitutaceae bacterium TAV2
          Length = 452

 Score = 39.1 bits (87), Expect = 0.088
 Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKF-DMVFIKELKRHVN-SIDAVLISH 353
           +KL  L+  G     C +LQI +   ++D G   K      + +  +  N  ID +L++H
Sbjct: 1   MKLTDLNRQGGIGANCTLLQIGDINLVIDSGLHPKIAGRQAVPDFAKLRNLEIDLILVTH 60

Query: 354 SDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMF-----MYDLYQAHKNVSEFDLFTLD 518
               H+G+LP  + +      + +T     + +M      +    +   N+ E+ LFT +
Sbjct: 61  CHLDHIGSLPVLMREHPRPPVMMSTASQMLVERMLHNSANVMKRQKEEDNIPEYPLFTHE 120

Query: 519 DVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           D+D    R   + +    + +     + IT   AGH  G
Sbjct: 121 DIDRLAPRFTGIPFGHPKKFRPHKDEIEITLHHAGHVAG 159


>UniRef50_A0UZ06 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 396

 Score = 39.1 bits (87), Expect = 0.088
 Identities = 22/69 (31%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
 Frame = +3

Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISHSDPLHLGALPYAVGKL 401
           Y+++ D+   L+D  WD  +   F+++L + +  ++IDA++I+H +P H G+L   + K+
Sbjct: 37  YIIR-DKKTVLIDTVWDP-YKEQFVEDLDKSIGLSNIDAIVINHMEPDHGGSLGLLMSKI 94

Query: 402 GLSCPIYAT 428
             + PIY T
Sbjct: 95  P-NTPIYCT 102


>UniRef50_Q8IB25 Cluster: Putative uncharacterized protein
           MAL8P1.64; n=3; Plasmodium|Rep: Putative uncharacterized
           protein MAL8P1.64 - Plasmodium falciparum (isolate 3D7)
          Length = 1313

 Score = 39.1 bits (87), Expect = 0.088
 Identities = 16/42 (38%), Positives = 28/42 (66%)
 Frame = +3

Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP 383
           L++CGWD+KF +  IK + R    ID ++I++    ++G+LP
Sbjct: 93  LMNCGWDDKFCLEDIKNVIRVCEVIDLIIITNHSLNYIGSLP 134


>UniRef50_A6E886 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Pedobacter sp. BAL39|Rep:
           Metallo-beta-lactamase superfamily protein - Pedobacter
           sp. BAL39
          Length = 460

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV----NSIDAVLI 347
           +KL     A + T   ++LQ+ ++  L+DCG D  ++    +E  ++       +D V++
Sbjct: 1   MKLTIWGAARQVTGSMHLLQLKDYNILIDCGLD--YEKETYQEENQYFPFDPADLDVVIL 58

Query: 348 SHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           +H+   H G LP  V ++G    I  T P   + ++ + D
Sbjct: 59  THAHIDHSGNLPTLV-RMGFQGQILCTPPTADLSELLLLD 97


>UniRef50_Q5ZWR4 Cluster: Metallo-beta lactamase family; n=4;
           Legionella pneumophila|Rep: Metallo-beta lactamase
           family - Legionella pneumophila subsp. pneumophila
           (strain Philadelphia 1 /ATCC 33152 / DSM 7513)
          Length = 453

 Score = 38.3 bits (85), Expect = 0.15
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLIS 350
           +KL  L      T   Y+L I   K L+DCG  + +  + ++    L    + IDAV+I+
Sbjct: 1   MKLTFLGATETVTGSKYLLTIGSKKILIDCGLFQGYKELRLRNWAPLPIDPHDIDAVIIT 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428
           H+   H G LP  V K G    IY T
Sbjct: 61  HAHIDHSGYLPLLV-KNGFQGKIYTT 85


>UniRef50_Q50EJ8 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=45; Lactobacillales|Rep:
           Metallo-beta-lactamase superfamily hydrolase -
           Lactobacillus reuteri
          Length = 593

 Score = 38.3 bits (85), Expect = 0.15
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCG--WDEK----FDMVFI--KELKRHV 323
           M + IK+    G  E     Y ++I++  F+LD G  + E      D+V    + L+ H 
Sbjct: 1   MDNNIKIIPFGGVRENGKNMYAVEIEDQIFILDTGLKYPENELMGIDVVIPDWEYLREHK 60

Query: 324 NSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503
           + I  V ++H     +GALPY +  +  + P++ +     + ++ +    + HK V +F+
Sbjct: 61  DKIVGVFLTHGHADSIGALPYFL--MDFNVPVFGSEMTIALAKLAV----KNHKEVKKFN 114

Query: 504 LFTLDDVDMAFD 539
            F + D   A D
Sbjct: 115 DFHVVDASTAID 126


>UniRef50_A3D3L5 Cluster: Putative uncharacterized protein; n=1;
           Shewanella baltica OS155|Rep: Putative uncharacterized
           protein - Shewanella baltica OS155
          Length = 338

 Score = 38.3 bits (85), Expect = 0.15
 Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
 Frame = +3

Query: 240 IDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHL-GALP 383
           +   KFL+DCG    F + + + +K+ +NS + ++++HSD  H+ GA P
Sbjct: 22  VSGIKFLVDCG----FKLTYQQHIKKKINSANFIILTHSDEDHINGAFP 66


>UniRef50_Q6MTU5 Cluster: CONSERVED HYPOTEHTICAL PROTEIN; n=3;
           Mollicutes|Rep: CONSERVED HYPOTEHTICAL PROTEIN -
           Mycoplasma mycoides subsp. mycoides SC
          Length = 583

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG--WDEK----FDMVFIK--ELKRHVNSID 335
           IK   L G  E     YVL+ID   F+LD G  + EK     D V  K   +K++   I 
Sbjct: 4   IKFTALGGQDERGKNLYVLEIDNDFFILDAGVKYPEKDILGIDTVIPKFDYIKQNKKKIK 63

Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIY 422
            + +++    ++GA+PY + +  +  PIY
Sbjct: 64  GIFLTNPSAYNMGAVPYLLKE--IKAPIY 90


>UniRef50_Q6ME06 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 259

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 30/112 (26%), Positives = 50/112 (44%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356
           I+K  C   +G +   C  L   + K L+D G   K     + E+   ++ IDA+LI+H 
Sbjct: 2   IMKGFCPLASGSKGN-CIYLGTSQTKVLIDAGISAKAIQNRLAEINVDISDIDAILITHE 60

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFT 512
              H+  L     KLG+  P+ A     K        + +A +N  +F +F+
Sbjct: 61  HSDHIQGLKVLAYKLGI--PVLANHETAK-------GIVEAFRNCPKFKIFS 103


>UniRef50_A6TSN2 Cluster: Beta-lactamase domain protein; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase
           domain protein - Alkaliphilus metalliredigens QYMF
          Length = 245

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
 Frame = +3

Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLG---ALPYAVGK 398
           Y+L+  E K L+DCG +      F  +    +N +DA+ ISH  P H+     + YA+G 
Sbjct: 22  YLLEDKEIKILVDCG-NGVLSRFF--QHCHDINELDAIFISHLHPDHMSDLMVMKYAIGI 78

Query: 399 LGLSCPIYATLPVY 440
             +   +  ++P+Y
Sbjct: 79  GQMQGKVKQSIPIY 92


>UniRef50_O31760 Cluster: UPF0036 protein ymfA; n=77;
           Firmicutes|Rep: UPF0036 protein ymfA - Bacillus subtilis
          Length = 555

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 8/96 (8%)
 Frame = +3

Query: 165 KMTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEK------FDMVF--IKELKRH 320
           K T  +++  L G GE     YV++ID   F++D G           D+V   I  L   
Sbjct: 4   KNTENVRIIALGGVGEIGKNLYVIEIDSDIFVVDAGLMHPENEMLGIDVVIPDISYLIER 63

Query: 321 VNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
            + + A+ ++H    ++G + Y + K  LS P+Y T
Sbjct: 64  ADRVKAIFLTHGHDENIGGVFYLLNK--LSVPVYGT 97


>UniRef50_A0YHA6 Cluster: DNA internalization-related competence
           protein ComEC/Rec2; n=1; marine gamma proteobacterium
           HTCC2143|Rep: DNA internalization-related competence
           protein ComEC/Rec2 - marine gamma proteobacterium
           HTCC2143
          Length = 790

 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 6/57 (10%)
 Frame = +3

Query: 231 VLQIDEFKFLLDCG--WDEKFDM---VFIKELKRH-VNSIDAVLISHSDPLHLGALP 383
           V+Q   +  + D G  W + FDM   V I  L+ H ++ ID+++ISH D  H G+LP
Sbjct: 530 VVQTRNYTLVYDVGARWGDDFDMAQAVLIPYLQDHGISHIDSLVISHGDNDHAGSLP 586


>UniRef50_Q8DE34 Cluster: Predicted exonuclease of the
           beta-lactamase fold involved in RNA processing; n=6;
           Vibrionales|Rep: Predicted exonuclease of the
           beta-lactamase fold involved in RNA processing - Vibrio
           vulnificus
          Length = 446

 Score = 36.7 bits (81), Expect = 0.47
 Identities = 28/126 (22%), Positives = 57/126 (45%)
 Frame = +3

Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380
           G    T  C+  +      L+DCG  +  D     E+   V  IDA++++H+   H+G +
Sbjct: 8   GKDTVTGSCHEFRAAGIALLIDCGLFQGKD-ARPPEVDFPVKHIDALVLTHAHIDHIGRI 66

Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKY 560
           P+ +   G S  IY T    ++  + + D  +    ++   L  +  +D+   R+  +KY
Sbjct: 67  PWLLA-AGFSGSIYCTEATAELVPLMLEDGLRLQLGLNHKQLHQV--LDLVKKRLKPVKY 123

Query: 561 NQSIEM 578
            + + +
Sbjct: 124 GEWLRL 129


>UniRef50_Q72GW5 Cluster: Cleavage and polyadenylation specificity
           factor, 100 kDa subunit; n=2; Thermus thermophilus|Rep:
           Cleavage and polyadenylation specificity factor, 100 kDa
           subunit - Thermus thermophilus (strain HB27 / ATCC
           BAA-163 / DSM 7039)
          Length = 431

 Score = 36.7 bits (81), Expect = 0.47
 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 1/126 (0%)
 Frame = +3

Query: 204 AGEETPPCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380
           A E T   ++L     + LLDCG +  K +             +DAVL++H+   H+G L
Sbjct: 9   AREVTGSAHLLLAGGRRVLLDCGMFQGKEEARNHAPFGFDPKEVDAVLLTHAHLDHVGRL 68

Query: 381 PYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKY 560
           P  + + G   P+YAT     + ++ + D  +    V +   F  +DV+ A   +  L+Y
Sbjct: 69  P-KLFREGYRGPVYATRATALLMEIVLEDALK----VMDEPFFGPEDVEEALGHLRPLEY 123

Query: 561 NQSIEM 578
            + + +
Sbjct: 124 GEWLRL 129


>UniRef50_A4VJP5 Cluster: Metallo-beta-lactamase superfamily
           protein; n=11; Gammaproteobacteria|Rep:
           Metallo-beta-lactamase superfamily protein - Pseudomonas
           stutzeri (strain A1501)
          Length = 505

 Score = 36.7 bits (81), Expect = 0.47
 Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 8/114 (7%)
 Frame = +3

Query: 186 LHCLSGAGEETPPCYVLQI-DEFKFLLDCGW-----DEKFD--MVFIKELKRHVNSIDAV 341
           L  L    + T  CY+++  D  + LL+CG      +E+ D    F  + K    S+DAV
Sbjct: 40  LSFLGAIQQVTGSCYLIETHDGARVLLECGMHQGRREEESDNRAAFAFDPK----SLDAV 95

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503
           ++SH+   H G LP  V  LG   P++ T    ++ ++ + D  Q  +  +E++
Sbjct: 96  VLSHAHIDHSGLLPRLVA-LGYRGPVHCTEATAELLELMLLDSAQIQEKDAEWE 148


>UniRef50_Q226C1 Cluster: Putative FEG protein; n=2; Tetrahymena
           thermophila SB210|Rep: Putative FEG protein -
           Tetrahymena thermophila SB210
          Length = 178

 Score = 36.7 bits (81), Expect = 0.47
 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
 Frame = +3

Query: 279 EKFDMVF-IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLP 434
           EK   ++ I E ++    ID VLISH    H+GALPY         PIY T P
Sbjct: 42  EKIKQIWNIPEKRKWDQIIDLVLISHFHLDHIGALPYFTEIYNYDGPIYMTSP 94


>UniRef50_A7DPN0 Cluster: Beta-lactamase domain protein; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Beta-lactamase domain protein - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 421

 Score = 36.7 bits (81), Expect = 0.47
 Identities = 18/65 (27%), Positives = 37/65 (56%)
 Frame = +3

Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509
           +DA++I+H+   H G +P     +  +  +YAT P + + ++ + D+ +  KN   FDL 
Sbjct: 52  LDAIIITHAHLDHSGNVPSLF--VSGNTDVYATPPTFDLSKLLIEDMLKIEKNSHPFDLP 109

Query: 510 TLDDV 524
            L+++
Sbjct: 110 ELNNM 114


>UniRef50_UPI000049831F Cluster: cleavage and polyadenylation
           specificity factor 73 kDa subunit, putative; n=1;
           Entamoeba histolytica HM-1:IMSS|Rep: cleavage and
           polyadenylation specificity factor 73 kDa subunit,
           putative - Entamoeba histolytica HM-1:IMSS
          Length = 755

 Score = 36.3 bits (80), Expect = 0.62
 Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 5/150 (3%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRH--VNSIDAVLISHSDPLH 368
           GAG E    C++L+      +LDCG    K        L  H  ++SI+ + ++H    H
Sbjct: 27  GAGREVGRSCFILKYMGHNIMLDCGVHPAKPHGEAALPLFEHADIDSIELLCVTHYHVDH 86

Query: 369 LGALPYAVGKLGLSCPIYATLPVYKM-GQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRI 545
             +LPY + +      +  T P  ++ G++F  + +Q    +         +V    DRI
Sbjct: 87  CASLPYLILERQFKGKVLMTPPTKEIFGELFK-EFHQMSSTIQPPKSVNPKEV---IDRI 142

Query: 546 VQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
             +K+++  E      G++I    AGH LG
Sbjct: 143 DTIKFHELQEYN----GMKIWCFNAGHILG 168


>UniRef50_Q9SRR3 Cluster: F21O3.24 protein; n=3; core
           eudicotyledons|Rep: F21O3.24 protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 620

 Score = 36.3 bits (80), Expect = 0.62
 Identities = 21/52 (40%), Positives = 27/52 (51%)
 Frame = +3

Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHK 485
           ID VLIS+  P+ L  LP+     G    IY T    K+GQ+ M D+   HK
Sbjct: 102 IDIVLISN--PMGLLGLPFLTQNPGFFAKIYMTEVTAKIGQLMMEDIVSMHK 151


>UniRef50_Q9FMW0 Cluster: Genomic DNA, chromosome 5, P1 clone:MLE2;
           n=8; Magnoliophyta|Rep: Genomic DNA, chromosome 5, P1
           clone:MLE2 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 528

 Score = 36.3 bits (80), Expect = 0.62
 Identities = 15/40 (37%), Positives = 27/40 (67%)
 Frame = +3

Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           ++R  + I+AV+I+H    H+GALP+ +  L  + PI+A+
Sbjct: 161 IRRWKHKIEAVVITHGHEDHIGALPWVIPALDPNTPIFAS 200


>UniRef50_Q9HKD3 Cluster: Putative uncharacterized protein Ta0668;
           n=2; Thermoplasma|Rep: Putative uncharacterized protein
           Ta0668 - Thermoplasma acidophilum
          Length = 322

 Score = 36.3 bits (80), Expect = 0.62
 Identities = 21/65 (32%), Positives = 34/65 (52%)
 Frame = +3

Query: 213 ETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAV 392
           +T   Y L+ D+  FL+D G  +      IK +++++  ID V I+H    HLG + Y  
Sbjct: 28  KTANIYRLETDDSAFLIDSGMSDNS----IKSIEQNLKKIDFVFITHLHIDHLGGVLYLH 83

Query: 393 GKLGL 407
            K G+
Sbjct: 84  EKYGI 88


>UniRef50_Q6D8S0 Cluster: Anaerobic nitric oxide reductase
           flavorubredoxin; n=58; root|Rep: Anaerobic nitric oxide
           reductase flavorubredoxin - Erwinia carotovora subsp.
           atroseptica (Pectobacterium atrosepticum)
          Length = 509

 Score = 36.3 bits (80), Expect = 0.62
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
 Frame = +3

Query: 240 IDEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISHSDPLHLGALPYAVGKLGLSC 413
           I E K +L    D KF   F++ L   V  N+ID ++I+H++  H GAL   + ++  + 
Sbjct: 40  IREEKTVLIDTVDHKFSREFVQNLMAEVDLNTIDYIVINHAEEDHAGALSELMARIP-NT 98

Query: 414 PIYAT 428
           PIY T
Sbjct: 99  PIYCT 103


>UniRef50_Q4SGI2 Cluster: Chromosome undetermined SCAF14594, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14594, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 588

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = +2

Query: 320 CKFNRCCTNITLGSSTFRSSSICSWKTRS*LSNICNSTGIQ 442
           C+F +C      G+S    SS C W+ +S ++N+ NS+ +Q
Sbjct: 62  CRFKKCLMRSASGASPSGRSSACCWEMQSAMNNMMNSSQLQ 102


>UniRef50_Q89VA5 Cluster: Bll1142 protein; n=7;
           Bradyrhizobiaceae|Rep: Bll1142 protein - Bradyrhizobium
           japonicum
          Length = 244

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 20/64 (31%), Positives = 31/64 (48%)
 Frame = +3

Query: 201 GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380
           G+G     C+ +   E  FL+DCG      +  +K L+   N ID +LI+H    H   L
Sbjct: 13  GSGGRLNTCFHVAGREANFLIDCGASA---LPALKRLEIDRNDIDLILITHFHGDHFAGL 69

Query: 381 PYAV 392
           P+ +
Sbjct: 70  PFVL 73


>UniRef50_Q2G7Y1 Cluster: Beta-lactamase-like protein; n=1;
           Novosphingobium aromaticivorans DSM 12444|Rep:
           Beta-lactamase-like protein - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 535

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDAVLIS 350
           ++L+    A   T  C+   + + + L+DCG        + +  + L   V+ ID V+++
Sbjct: 3   LRLNVHGAARTVTGSCFEFVLGDMRLLVDCGLFQGSRSLEALNHEPLDFDVHKIDGVIVT 62

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497
           H+   H G LP    + G   PI+ T     + ++ + D  +  ++ +E
Sbjct: 63  HAHIDHSGLLPRLAAE-GYEGPIWCTPETAALLKVMLADAGRIQESEAE 110


>UniRef50_Q1NVJ9 Cluster: Beta-lactamase-like:RNA-metabolising
           metallo-beta-lactamase; n=2; Deltaproteobacteria|Rep:
           Beta-lactamase-like:RNA-metabolising
           metallo-beta-lactamase - delta proteobacterium MLMS-1
          Length = 469

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG-WDEKFDMVFIKELKRHVN--SIDAVLIS 350
           +KL     AG  T   ++L+++  + LLDCG +  K    F    +   N   +D +++S
Sbjct: 1   MKLTFHGAAGTVTGSQHLLEVNGKRILLDCGLFQGKRKEAFELNRQGFCNGKKLDCLILS 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF---------- 500
           H+   H G +P  V K G    IY T     +  + + D     +   +F          
Sbjct: 61  HAHIDHSGNIPCLV-KSGFDGDIYTTQATRDLCAIMLMDSANIQEQDVQFVNKRRERNGQ 119

Query: 501 ----DLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
                L+T +DV +A  + V +   +  E+     G+ +T   AGH LG
Sbjct: 120 QPFEPLYTKEDVVLAMPQFVGIAPGRRREIYP---GIHLTLAEAGHMLG 165


>UniRef50_A6Q9T8 Cluster: RNA-metabolising metallo-beta-lactamase;
           n=2; Sulfurovum sp. NBC37-1|Rep: RNA-metabolising
           metallo-beta-lactamase - Sulfurovum sp. (strain NBC37-1)
          Length = 467

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
 Frame = +3

Query: 201 GAGEE-TPPCYVLQIDE-FKFLLDCG-WDEKFDMVFIKELKRHVNSIDAVLISHSDPLHL 371
           GA E  T  C++L+ID   + L+DCG +  + +            S+D +L++H+   H+
Sbjct: 8   GAAEVVTGSCHLLEIDSGTRILVDCGMFQGREEHRNYGLFDFDAKSVDYLLVTHAHLDHV 67

Query: 372 GALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           G +P  V K G S  I AT   + + ++ + D
Sbjct: 68  GRIPKLV-KEGFSGTIVATDATFALAEVVLLD 98


>UniRef50_A4EC58 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 459

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 18/42 (42%), Positives = 26/42 (61%)
 Frame = +3

Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP 383
           L+DCG DE+   V    ++ +V+ IDAV ++H D  H G LP
Sbjct: 238 LVDCGLDER---VVAALVRNNVHHIDAVFVTHWDEDHWGGLP 276


>UniRef50_A1ZG78 Cluster: Exonuclease of the beta-lactamase fold
           involved in RNA processing; n=1; Microscilla marina ATCC
           23134|Rep: Exonuclease of the beta-lactamase fold
           involved in RNA processing - Microscilla marina ATCC
           23134
          Length = 476

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 9/105 (8%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQID-EFKFLLDCGWD---EKFDMVFIKELKRHV-----NSI 332
           ++L     A + T   ++L++D +FK L+DCG D   E+  +     L + +     + I
Sbjct: 1   MRLTFWGAARQVTGSMHLLELDNDFKVLIDCGHDLERERKPLTDENGLYQGIFPFEPSQI 60

Query: 333 DAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           +AV+++H+   H G LP  V + G    IY T   Y +  + ++D
Sbjct: 61  NAVVLTHAHIDHSGFLPNLV-REGFEGVIYCTDATYDLTNLLLHD 104


>UniRef50_A7PHF3 Cluster: Chromosome chr17 scaffold_16, whole genome
           shotgun sequence; n=4; Viridiplantae|Rep: Chromosome
           chr17 scaffold_16, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 880

 Score = 35.9 bits (79), Expect = 0.82
 Identities = 15/40 (37%), Positives = 26/40 (65%)
 Frame = +3

Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           +K+  + I+AV+I+H    H+GALP+ +  L    PI+A+
Sbjct: 129 IKKWSHKIEAVVITHGHEDHIGALPWVIPALDSHTPIFAS 168


>UniRef50_Q4TC63 Cluster: Chromosome undetermined SCAF7053, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF7053, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 810

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
 Frame = +3

Query: 201 GAGEETP-PCYVLQIDEFKFLLDCGWD---EKFDMVFIKELKRHVNSIDAVLISHSDPLH 368
           GAG+E    C +L+    K +LDCG     E  D +   +L      ID +LISH    H
Sbjct: 15  GAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAE-IDLLLISHFHLDH 73

Query: 369 LGALPYAVGKL---GLSCPIYATLPVYK 443
            GALP+ + K    G +   +AT  +Y+
Sbjct: 74  CGALPWFLQKTSFKGRTFMTHATKAIYR 101


>UniRef50_Q9AA00 Cluster: Metallo-beta-lactamase family protein;
           n=2; Caulobacter|Rep: Metallo-beta-lactamase family
           protein - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 530

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKELKRHVNSIDA 338
           MT  +  H    AG  T  C  L       L+DCG     +    +  +        +DA
Sbjct: 1   MTISLTFH--GAAGCVTGFCARLVTPRTTVLIDCGMFQGSKTLKALNYQPFPFDAGQVDA 58

Query: 339 VLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497
           VL++H+   H G LP  +   G   PIYAT     +G + + D     +N  E
Sbjct: 59  VLLTHAHIDHSGLLPKLM-LAGFEGPIYATAATRDLGAVMLVDAGGIQENEVE 110


>UniRef50_Q5QU60 Cluster: Predicted exonuclease of the
           beta-lactamase fold; n=2; Alteromonadales|Rep: Predicted
           exonuclease of the beta-lactamase fold - Idiomarina
           loihiensis
          Length = 452

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
 Frame = +3

Query: 195 LSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLISHSDPL 365
           L GA   T   Y+++ +  + L+DCG  + +  +  +    L   +N +D V+++H+   
Sbjct: 6   LGGAETVTGSKYLVETESTRILIDCGLFQGYKWLRRRNWQPLPMGINQVDGVVLTHAHLD 65

Query: 366 HLGALPYAVGKLGLSCPIYA 425
           H G +P  + K G   P++A
Sbjct: 66  HSGFVP-VLYKEGFRGPVFA 84


>UniRef50_Q3ADT3 Cluster: Anaerobic nitric oxide reductase
           flavorubredoxin; n=6; Clostridiales|Rep: Anaerobic
           nitric oxide reductase flavorubredoxin -
           Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
           6008)
          Length = 396

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 2/49 (4%)
 Frame = +3

Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHV--NSIDAVLISHSDPLHLGALP 383
           DE   L+D  W  KFD  ++K+L   +  N ID V+  H +  H GALP
Sbjct: 42  DEKVALIDTAWI-KFDKEYVKKLSEEIDLNKIDYVVALHGEIDHSGALP 89


>UniRef50_Q1B028 Cluster: Beta-lactamase-like protein; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           Beta-lactamase-like protein - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 813

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/94 (27%), Positives = 39/94 (41%)
 Frame = +3

Query: 165 KMTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVL 344
           K    +    L GAGE     ++L     + L+D G           + +  +  +D  +
Sbjct: 387 KSRPTLAFRALGGAGEVGGSSHLLDFGSTRVLVDAGIKPDGRGQLAPDFEE-IGPLDGAI 445

Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKM 446
           I+H+   H GALP  V K     PIY T P  K+
Sbjct: 446 ITHAHLDHCGALPLLV-KNHPQLPIYCTPPSAKL 478


>UniRef50_Q194D1 Cluster: Beta-lactamase-like; n=3; Clostridia|Rep:
           Beta-lactamase-like - Desulfitobacterium hafniense
           (strain DCB-2)
          Length = 570

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG---WDEKFDMVFIKELKRHVNSIDAVLIS 350
           +KL+    A   T   Y+++ + ++ L+DCG     +    +   +   +   ++AV+++
Sbjct: 1   MKLYFYGAAQVVTGSSYLVESEGYRVLIDCGLFQGSKALKELNYGDFPYNPAELNAVILT 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           H+   H G +P  + K G    IYAT    K+  + + D
Sbjct: 61  HAHTDHSGLIPKLI-KYGFQGKIYATPETIKLCSVMLPD 98


>UniRef50_Q12E81 Cluster: Beta-lactamase-like; n=14;
           Proteobacteria|Rep: Beta-lactamase-like - Polaromonas
           sp. (strain JS666 / ATCC BAA-500)
          Length = 453

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/110 (22%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKE---LKRHVNSIDAVLIS 350
           ++L  L      T   Y++Q D+ + L+DCG  + +  + ++    L     +IDAV+++
Sbjct: 1   MRLQFLGATDTVTGSKYLVQHDKARVLVDCGLFQGYKQLRLRNWSPLPVKPAAIDAVVLT 60

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEF 500
           H+   H G LP  + + G    +Y T     + ++ + D     +  +E+
Sbjct: 61  HAHIDHSGYLP-LLARQGFRGKVYCTPATADLCRILLPDSGHLQEEEAEY 109


>UniRef50_A6Q3H4 Cluster: RNA-metabolising metallo-beta-lactamase;
           n=8; Proteobacteria|Rep: RNA-metabolising
           metallo-beta-lactamase - Nitratiruptor sp. (strain
           SB155-2)
          Length = 462

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
 Frame = +3

Query: 201 GAGEE-TPPCYVLQIDE-FKFLLDCGWDEKFD-MVFIKELKRHVNSIDAVLISHSDPLHL 371
           GA E  T  C+ ++ D+  K L+DCG  +  D     + L  +   ID +L++H    H+
Sbjct: 8   GAAEVVTGSCHFVKFDDGTKALIDCGMFQGLDEWKNYEPLGFNAKEIDYLLVTHGHLDHV 67

Query: 372 GALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFD 503
           G +P  + K G    I AT   +++ ++ + D   AH    +F+
Sbjct: 68  GRIP-LLYKEGFRGKIIATAATFELMKIVLLD--TAHLMQEDFE 108


>UniRef50_A1S0I1 Cluster: Beta-lactamase domain protein; n=1;
           Thermofilum pendens Hrk 5|Rep: Beta-lactamase domain
           protein - Thermofilum pendens (strain Hrk 5)
          Length = 441

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/102 (28%), Positives = 51/102 (50%)
 Frame = +3

Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLF 509
           ++AV +SH    HL A+P A+ + G + PIY + P  ++G    Y      ++     LF
Sbjct: 55  VEAVFVSHLHEDHLAAVP-ALVRRGFNGPIYMSAPTAELGIKQWYKWTVLEEDGK--PLF 111

Query: 510 TLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           T +D D A  ++V+   + S+   G    + +    +GH+LG
Sbjct: 112 TEEDCDEA-RKMVKTVGDGSVVTSG---DVEVAFHQSGHALG 149


>UniRef50_A4STH4 Cluster: Anaerobic nitric oxide reductase
           flavorubredoxin; n=3; Gammaproteobacteria|Rep: Anaerobic
           nitric oxide reductase flavorubredoxin - Aeromonas
           salmonicida (strain A449)
          Length = 521

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
 Frame = +3

Query: 276 DEKFDMVFIKELKRHVN--SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           D KF   F++ L   ++  SID ++I+H++  H GAL   + ++    PIY T
Sbjct: 52  DHKFSREFVQNLAAEIDLASIDVIVINHAEEDHAGALTELMARIP-GTPIYCT 103


>UniRef50_Q31DU4 Cluster: Phosphonate metabolism accessory protein
           precursor; n=2; Gammaproteobacteria|Rep: Phosphonate
           metabolism accessory protein precursor - Thiomicrospira
           crunogena (strain XCL-2)
          Length = 255

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHL-GALPYAVGKL 401
           C VL+++  +FL+D G+      + ++E K    S+DAVL++H    H+ G  P   G +
Sbjct: 43  CGVLEVNGVRFLIDAGY------LGLEE-KFPPGSLDAVLLTHFHMDHVQGLFPIRWG-M 94

Query: 402 GLSCPIYATLPVYKMGQMFMY-DLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQS--I 572
           G S P+++    +    +F Y  ++   K    F+ F    + +    +V  K      +
Sbjct: 95  GESIPVFSPDDPHGCDDLFKYPGIFDFSKKSLPFEPFHFKGIKITPVPLVHSKLTMGYIV 154

Query: 573 EMKGKGL 593
           E  GK L
Sbjct: 155 EFNGKRL 161


>UniRef50_Q1PVS7 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Putative
           uncharacterized protein - Candidatus Kuenenia
           stuttgartiensis
          Length = 468

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN----SIDAVL 344
           +I+L  +  A   T   ++++      LLDCG  +        E  R+ +     +DA++
Sbjct: 1   MIELEFIGAAKTVTGSKHLIRTSRASVLLDCGLFQGHRKE-ADEKNRNFSIDGKQLDAIV 59

Query: 345 ISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           +SH+   H GALP  + K G   PIYAT
Sbjct: 60  LSHAHIDHSGALP-CIFKNGYRGPIYAT 86


>UniRef50_Q4UBM2 Cluster: Cleavage and polyadenylation specificty
           factor, subunit, putative; n=4; Piroplasmida|Rep:
           Cleavage and polyadenylation specificty factor, subunit,
           putative - Theileria annulata
          Length = 1282

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 18/174 (10%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN--SIDAV 341
           M   +++  L    E    C  ++ D    + DCG       V    +   V+   ++  
Sbjct: 1   MDDRVRITVLGAGCEVGRSCVYVERDNSCLMFDCGLHPALSGVGALPVFEAVDISKVEVC 60

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAH-----KNVSEFD- 503
           L++H    H GA+PY + K   +  I  T     +  +   D  +       K + + D 
Sbjct: 61  LVTHFHLDHCGAVPYLLSKTKFNGRILMTPATKSICHLLWTDYARMEQLLTVKTIFDDDD 120

Query: 504 ----------LFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
                     L++ +DV+ A DRI  + ++Q I +      ++I+   AGH LG
Sbjct: 121 GMDELVCGSGLYSFEDVEYALDRIETIDFHQEITVN----DIKISCYRAGHVLG 170


>UniRef50_Q8RAH0 Cluster: Predicted hydrolase of the
           metallo-beta-lactamase superfamily; n=9; Bacteria|Rep:
           Predicted hydrolase of the metallo-beta-lactamase
           superfamily - Thermoanaerobacter tengcongensis
          Length = 554

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW----DEKF--DMVF--IKELKRHVNSID 335
           +K+  L G  E      V +      ++DCG     DE    D+V   I  L ++   + 
Sbjct: 7   LKIIPLGGLNEIGKNMTVFEYGNDIIVVDCGLAFPDDEMLGIDLVIPDITYLLKNREKVK 66

Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           A++++H    H+GALPY + +L +  PIY T
Sbjct: 67  AIVLTHGHEDHIGALPYVLKQLNV--PIYGT 95


>UniRef50_Q41CQ7 Cluster: Beta-lactamase-like; n=1; Exiguobacterium
           sibiricum 255-15|Rep: Beta-lactamase-like -
           Exiguobacterium sibiricum 255-15
          Length = 328

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWD-EKFDMVF---IKELKRHVNSIDAVLISHSDPLHLGALPYAV 392
           CYVL+ D    L+DCG D E+        ++++   V+ +D V+++H    H G L Y  
Sbjct: 23  CYVLRTDSENILIDCGPDTEQAWQAMQDGLQKIGLTVSMLDKVIVTHHHADHAG-LAYRF 81

Query: 393 GKLGLSCPIYATL-PVYKMGQMFM 461
            + G+    +A L P  +  Q F+
Sbjct: 82  SEQGIPIYGHARLRPYLEQDQAFL 105


>UniRef50_Q97DE0 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=11; Clostridia|Rep: Metallo-beta-lactamase
           superfamily hydrolase - Clostridium acetobutylicum
          Length = 261

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 20/67 (29%), Positives = 30/67 (44%)
 Frame = +3

Query: 243 DEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIY 422
           D  K L+D G   K     +KE+K   N ID + ++H    H+  +     K  +  PIY
Sbjct: 20  DNSKVLIDAGLSGKTIEKALKEIKEDPNEIDGIFVTHEHSDHIKGVGVLSRKYNI--PIY 77

Query: 423 ATLPVYK 443
           A    +K
Sbjct: 78  ANELTWK 84


>UniRef50_Q5NLC0 Cluster: Metallo-beta-lactamase hydrolase subunit;
           n=8; Sphingomonadales|Rep: Metallo-beta-lactamase
           hydrolase subunit - Zymomonas mobilis
          Length = 546

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = +3

Query: 288 DMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           D+ FI+E       +  ++I+H    H+GA+PY    LG+  PIYAT
Sbjct: 55  DIEFIEE---RAKDLLGIVITHGHEDHIGAIPYLAADLGV--PIYAT 96


>UniRef50_Q83XN5 Cluster: Putative beta-lactamase; n=1; Streptomyces
           cattleya|Rep: Putative beta-lactamase - Streptomyces
           cattleya
          Length = 329

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 15/38 (39%), Positives = 23/38 (60%)
 Frame = +3

Query: 315 RHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           RH+ + D +L++H    H+G LPY + K   S P+ AT
Sbjct: 110 RHLRAADLILLTHGHYDHIGDLPYVMRKFP-SAPVVAT 146


>UniRef50_Q3Y227 Cluster: Beta-lactamase-like; n=1; Enterococcus
           faecium DO|Rep: Beta-lactamase-like - Enterococcus
           faecium DO
          Length = 274

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
 Frame = +3

Query: 252 KFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIY--- 422
           K+L D G ++K  +    ++   +N ++AV+ISH    H G L Y   K G + PIY   
Sbjct: 32  KYLFDAGANKKL-VYNATKMGETLNDLEAVIISHGHSDHTGGLRYL--KSG-NAPIYTAE 87

Query: 423 -ATLPVY-KMGQMFMY 464
             TLP Y K+   F+Y
Sbjct: 88  GVTLPHYLKILTTFLY 103


>UniRef50_Q024Z8 Cluster: Beta-lactamase domain protein precursor;
           n=1; Solibacter usitatus Ellin6076|Rep: Beta-lactamase
           domain protein precursor - Solibacter usitatus (strain
           Ellin6076)
          Length = 269

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 22/86 (25%), Positives = 39/86 (45%)
 Frame = +3

Query: 171 TSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLIS 350
           T+I+K  C+  +G       +L  +  + L+D G   +     +  +   + SIDA++++
Sbjct: 9   TNIVKF-CVLASGSSGNAA-LLATENTRILVDAGLSMRELRKRLALIGETLESIDAIIVT 66

Query: 351 HSDPLHLGALPYAVGKLGLSCPIYAT 428
           H    H+  LP      GL   IY T
Sbjct: 67  HEHSDHVSGLPVLARAKGLRAVIYMT 92


>UniRef50_A6PE29 Cluster: Beta-lactamase domain protein; n=1;
           Shewanella sediminis HAW-EB3|Rep: Beta-lactamase domain
           protein - Shewanella sediminis HAW-EB3
          Length = 526

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +3

Query: 216 TPPCYVLQIDE-FKFLLDCGWDEKFDMVFIKELKR-----HVNSIDAVLISHSDPLHLGA 377
           T  C+ L I+E    L+DCG  +  +       ++      + SI A+L++H    H+G 
Sbjct: 19  TGSCHQLVINEKSSLLIDCGLFQGAETAGSSNAEQLKIAFDIGSITALLVTHCHIDHVGR 78

Query: 378 LPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           +PY +   G   PI+AT     +  M + D
Sbjct: 79  IPYLLA-AGFDQPIFATTATAALLPMVIED 107


>UniRef50_Q7QUX2 Cluster: GLP_577_37199_34023; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_577_37199_34023 - Giardia lamblia
           ATCC 50803
          Length = 1058

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 15/57 (26%), Positives = 33/57 (57%)
 Frame = +3

Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGK 398
           Y+L I++   L+DCG    ++  +++    H+++I A+L++ +   H GA  Y + +
Sbjct: 19  YLLTINDTLLLVDCGLAAPYE-TYLRVYDDHIDNISAILLTSAALEHAGACLYILSR 74


>UniRef50_Q6BHT7 Cluster: Similar to CA2422|IPF14997 Candida
           albicans IPF14997 unknown function; n=1; Debaryomyces
           hansenii|Rep: Similar to CA2422|IPF14997 Candida
           albicans IPF14997 unknown function - Debaryomyces
           hansenii (Yeast) (Torulaspora hansenii)
          Length = 228

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 18/54 (33%), Positives = 29/54 (53%)
 Frame = +3

Query: 402 GLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYN 563
           GLS  I   L  YK+GQ   + +    +N+S+  +F    +DM  D I+ +K+N
Sbjct: 87  GLSIQIDKLLTEYKLGQAIEHYIEITGENISKDLIFEKICIDMVDDSIIDIKFN 140


>UniRef50_A2SUA2 Cluster: Beta-lactamase domain protein; n=1;
           Methanocorpusculum labreanum Z|Rep: Beta-lactamase
           domain protein - Methanocorpusculum labreanum (strain
           ATCC 43576 / DSM 4855 / Z)
          Length = 271

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 18/62 (29%), Positives = 33/62 (53%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLG 404
           C+ ++    K LLD G+ + F +   K+L   ++++  V+ISH    H G LP+ + +  
Sbjct: 28  CFYIEDGTEKILLDTGYSDLF-IRNAKKLGTDLSALTKVVISHGHDDHTGGLPHLLERFD 86

Query: 405 LS 410
            S
Sbjct: 87  TS 88


>UniRef50_P54122 Cluster: UPF0036 protein Cgl1970/cg2160; n=31;
           Actinobacteria (class)|Rep: UPF0036 protein
           Cgl1970/cg2160 - Corynebacterium glutamicum
           (Brevibacterium flavum)
          Length = 718

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 8/91 (8%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCG------WDEKFDMVF--IKELKRHVNSID 335
           ++++ L G  E      V + +    ++DCG       +   D++      ++ H++ +D
Sbjct: 155 LRIYALGGISEIGRNMTVFEYNNRLLIVDCGVLFPSSGEPGVDLILPDFGPIEDHLHRVD 214

Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           A++++H    H+GA+P+ + KL    PI A+
Sbjct: 215 ALVVTHGHEDHIGAIPWLL-KLRNDIPILAS 244


>UniRef50_Q9NV88 Cluster: Integrator complex subunit 9; n=41;
           Eumetazoa|Rep: Integrator complex subunit 9 - Homo
           sapiens (Human)
          Length = 658

 Score = 33.9 bits (74), Expect = 3.3
 Identities = 17/41 (41%), Positives = 23/41 (56%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFI 302
           +KL+CLSG    T PC VL+      +LDCG D    + F+
Sbjct: 1   MKLYCLSG--HPTLPCNVLKFKSTTIMLDCGLDMTSTLNFL 39



 Score = 32.7 bits (71), Expect = 7.6
 Identities = 16/50 (32%), Positives = 30/50 (60%)
 Frame = +3

Query: 321 VNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDL 470
           ++++D +LIS+   +   ALPY     G +  +YAT P  ++G++ M +L
Sbjct: 93  LSTVDVILISNYHCMM--ALPYITEHTGFTGTVYATEPTVQIGRLLMEEL 140


>UniRef50_Q9K9I5 Cluster: BH2662 protein; n=43; Bacteria|Rep: BH2662
           protein - Bacillus halodurans
          Length = 555

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
 Frame = +3

Query: 186 LHCLSGAGEETPPCYVLQIDEFKFLLDCGW----DEKFDMVFI----KELKRHVNSIDAV 341
           ++ L G GE     Y +Q  +   L+D G     DE   + ++      L ++ N I  +
Sbjct: 11  VYALGGLGEIGKNTYAVQFQDEIILIDAGIKFPEDELLGIDYVIPDYSYLVKNENKIKGL 70

Query: 342 LISHSDPLHLGALPYAVGKLGLSCPIY 422
            I+H    H+G +PY + ++ +  PIY
Sbjct: 71  FITHGHEDHIGGIPYLLREVNI--PIY 95


>UniRef50_Q97D03 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=1; Clostridium acetobutylicum|Rep:
           Metallo-beta-lactamase superfamily hydrolase -
           Clostridium acetobutylicum
          Length = 245

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 19/55 (34%), Positives = 35/55 (63%), Gaps = 4/55 (7%)
 Frame = +3

Query: 228 YVLQIDEFKF-LLDCGWDEKFDMVFIKELKRH---VNSIDAVLISHSDPLHLGAL 380
           Y+L+I+E ++ L+D G+ E + + F+K LK +   +N I  V+++H    H+G L
Sbjct: 14  YLLRINENRYVLIDTGYKEDWKL-FLKRLKENGIKINEISYVILTHHHDDHVGFL 67


>UniRef50_Q81QL9 Cluster: Hydrolase, putative; n=10; Firmicutes|Rep:
           Hydrolase, putative - Bacillus anthracis
          Length = 217

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 17/50 (34%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
 Frame = +3

Query: 243 DEFKFLLDCGWDEKFDMVFIKELKR---HVNSIDAVLISHSDPLHLGALP 383
           DE   L+D G+  +F+ + + E+KR    V+ +  V+++H D  H+G+LP
Sbjct: 27  DEMAVLIDTGFPGQFEDIQV-EMKRVGVSVDKLKVVILTHQDIDHIGSLP 75


>UniRef50_Q748A2 Cluster: Metallo-beta-lactamase family protein;
           n=11; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Geobacter sulfurreducens
          Length = 561

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = +3

Query: 300 IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           I  L+     +  +L++H    H+GALPY + +L L  P+Y T
Sbjct: 62  ITYLRERAGRVRGILLTHGHEDHIGALPYVLQELSL--PLYGT 102


>UniRef50_Q1DC87 Cluster: Metallo-beta-lactamase family protein;
           n=2; Cystobacterineae|Rep: Metallo-beta-lactamase family
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 546

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 15/40 (37%), Positives = 25/40 (62%)
 Frame = +3

Query: 309 LKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
           LK++   +  VL++H    HLGALPY + ++ +  P+Y T
Sbjct: 53  LKQNAAQLKGVLLTHGHEDHLGALPYLLNEVPV--PVYGT 90


>UniRef50_A6G7H1 Cluster: Serine/threonine kinase family protein;
           n=1; Plesiocystis pacifica SIR-1|Rep: Serine/threonine
           kinase family protein - Plesiocystis pacifica SIR-1
          Length = 914

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 22/62 (35%), Positives = 35/62 (56%)
 Frame = +3

Query: 441 KMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPA 620
           ++GQ+F  DL +AH  ++E  L  L D+   + +  Q + +QSIE   K L +  + LP 
Sbjct: 639 RLGQLFA-DLTEAHDGLAEAKL--LSDIGTVYSK--QQEQDQSIEYFTKALQIYESRLPP 693

Query: 621 GH 626
           GH
Sbjct: 694 GH 695


>UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2;
           Roseiflexus|Rep: Beta-lactamase domain protein -
           Roseiflexus sp. RS-1
          Length = 205

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 19/60 (31%), Positives = 31/60 (51%)
 Frame = +3

Query: 336 AVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTL 515
           A+L++H+ P H+GAL     +LG+  P++A    +  G +   D   AH+ V      TL
Sbjct: 49  AILLTHTHPDHIGALDEMRNRLGV--PVFAHAGPHASGVVLPVDRTLAHREVITVGASTL 106


>UniRef50_A3TIY7 Cluster: Putative uncharacterized protein; n=1;
           Janibacter sp. HTCC2649|Rep: Putative uncharacterized
           protein - Janibacter sp. HTCC2649
          Length = 263

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 23/71 (32%), Positives = 34/71 (47%)
 Frame = +3

Query: 228 YVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGL 407
           Y+++    + L+D GW     ++ + +       IDAVL+SHS P H   L   +    L
Sbjct: 37  YLVEASGQRILMDPGWATFQGLLRLADPLE----IDAVLVSHSHPDHCADLLPLLRSRAL 92

Query: 408 SCPIYATLPVY 440
           S P    LPVY
Sbjct: 93  SEPAADPLPVY 103


>UniRef50_A5BGD5 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 665

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 21/61 (34%), Positives = 30/61 (49%)
 Frame = +3

Query: 318 HVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSE 497
           +V  ID VLIS   P+ +  LP+     G    IY T    ++GQ+ M DL   +K   +
Sbjct: 115 NVPFIDVVLIS--SPMGMLGLPFLSRVNGFRAKIYVTEVTARIGQLLMEDLVLMNKEFRQ 172

Query: 498 F 500
           F
Sbjct: 173 F 173


>UniRef50_Q4YUZ6 Cluster: Putative uncharacterized protein; n=4;
           Plasmodium (Vinckeia)|Rep: Putative uncharacterized
           protein - Plasmodium berghei
          Length = 1171

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 12/42 (28%), Positives = 25/42 (59%)
 Frame = +3

Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP 383
           L++CGWD+ F +  +K + +    +D + I++    ++G LP
Sbjct: 100 LINCGWDDNFCLDDVKNIIKVCEYVDIIFITNHGLSYVGCLP 141


>UniRef50_Q59M67 Cluster: Potential response regulator protein; n=2;
           Candida albicans|Rep: Potential response regulator
           protein - Candida albicans (Yeast)
          Length = 282

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 16/47 (34%), Positives = 23/47 (48%)
 Frame = +3

Query: 219 PPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSD 359
           P C+++QI + K + D    + FD +FI      VN ID  L    D
Sbjct: 178 PKCHIVQIQDSKLVKDLLHKQSFDSIFIDIEMPDVNGIDIFLFVRQD 224


>UniRef50_UPI0000E0E9AB Cluster: DNA internalization-related
           competence protein ComEC/Rec2; n=1; alpha
           proteobacterium HTCC2255|Rep: DNA
           internalization-related competence protein ComEC/Rec2 -
           alpha proteobacterium HTCC2255
          Length = 745

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 7/85 (8%)
 Frame = +3

Query: 231 VLQIDEFKFLLDCGWD--EKFDMVFIKEL-----KRHVNSIDAVLISHSDPLHLGALPYA 389
           +L +++  ++ D G D  E F+MV    L     + H+N I A+ ISH D  H G +P  
Sbjct: 498 LLLVNDSAYVFDVGNDFGESFNMVNSVLLAYVNAQPHIN-IKALYISHFDKDHAGGIPRF 556

Query: 390 VGKLGLSCPIYATLPVYKMGQMFMY 464
           +    L+ PIY+T    + GQ  ++
Sbjct: 557 ITYFPLT-PIYSTHEGCRQGQSHLW 580


>UniRef50_Q6N2A1 Cluster: Beta-lactamase-like; n=12;
           Rhizobiales|Rep: Beta-lactamase-like - Rhodopseudomonas
           palustris
          Length = 542

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
 Frame = +3

Query: 216 TPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHV-----NSIDAVLISHSDPLHLGAL 380
           T  CY+ +    +FL+DCG  +      +KEL         + IDAVL++H+   H G L
Sbjct: 15  TGSCYLFETKGKRFLVDCGLFQGHKT--LKELNYGAFPFRPSEIDAVLLTHAHIDHCGLL 72

Query: 381 PYAVGKLGLSCPIYAT 428
           P  V + G    I AT
Sbjct: 73  PKLV-REGFKGRILAT 87


>UniRef50_A7H6H0 Cluster: Beta-lactamase domain protein; n=2;
           Anaeromyxobacter|Rep: Beta-lactamase domain protein -
           Anaeromyxobacter sp. Fw109-5
          Length = 550

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 7/94 (7%)
 Frame = +3

Query: 168 MTSIIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGW---DEKFDMVFIKE----LKRHVN 326
           M   +++  L G GE    C  ++ D    ++DCG    +E   +  I      L+    
Sbjct: 1   MAPPVRIVPLGGLGEIGMNCMAIEADGRMAVVDCGILFPNEPIGVDVIAPDLGWLRERRE 60

Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYAT 428
            + A+ ++H    H+GALP+ + +  +  P+Y T
Sbjct: 61  QVGAIYLTHGHEDHIGALPFLLRE--VKAPVYGT 92


>UniRef50_A6LMC9 Cluster: Beta-lactamase domain protein; n=1;
           Thermosipho melanesiensis BI429|Rep: Beta-lactamase
           domain protein - Thermosipho melanesiensis BI429
          Length = 247

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
 Frame = +3

Query: 252 KFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIY--- 422
           + L D G  + F +   K++K  +  I  +++SH    H+G L Y +GK  ++ P+Y   
Sbjct: 28  EILFDTGASDVF-IKNAKKMKVDLRGIKKIVVSHGHYDHVGGLKYLIGK--VNAPVYIHK 84

Query: 423 -ATLPVYKMGQMFM 461
            A +P Y  G  F+
Sbjct: 85  NAVIPKYS-GDRFV 97


>UniRef50_A5K7P0 Cluster: RNA-metabolising metallo-beta-lactamase
           domain containing protein; n=1; Plasmodium vivax|Rep:
           RNA-metabolising metallo-beta-lactamase domain
           containing protein - Plasmodium vivax
          Length = 911

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 19/56 (33%), Positives = 26/56 (46%)
 Frame = +3

Query: 300 IKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYD 467
           I  LKR    ID V+ISH    H+GALP+    L     I  + P   +  + + D
Sbjct: 100 INNLKRINEMIDCVIISHFHMDHIGALPFFTEILKYRGTILMSYPTKALSPILLLD 155


>UniRef50_A5K5Q9 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium vivax|Rep: Putative uncharacterized protein -
           Plasmodium vivax
          Length = 1308

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 7/110 (6%)
 Frame = +3

Query: 258 LLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALP---YAVGKLGLSCPIYAT 428
           L++CGWD++F    +K + R    +D +LI++     +G  P     + K G   PI   
Sbjct: 110 LINCGWDDQFRTEDVKNVLRVCEYVDLLLITNHGLNFVGCAPLLFQELQKRGRKIPIICH 169

Query: 429 LPVYKMGQMFMYDLYQAHKNVSEFDLFTLDD----VDMAFDRIVQLKYNQ 566
             V    +  +   ++   + + F  F  D+    V+  F  +  L++ +
Sbjct: 170 EYVKSYSKYVLLSYFKCTSSCNFFKSFKDDEYVKMVNELFYNVTSLEFRE 219


>UniRef50_A0D1M0 Cluster: Chromosome undetermined scaffold_34, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_34,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 747

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 13/143 (9%)
 Frame = +3

Query: 246 EFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYA 425
           + + +LDCG +++ +   IK     +     VL+S     + G LP  + +  +     +
Sbjct: 29  KLQIMLDCGLNQRLECNHIKHYMNKIQKSKLVLLSQPSIEYAGGLP-LISEFQIK--TLS 85

Query: 426 TLPVYKMGQMFMYD----LYQA--HKNVSEFDL-----FTLDDVDMAFDRIVQLKYNQSI 572
           T P+ + G     D    L QA   K + E D        LD  D A+ +I  LK+ Q+ 
Sbjct: 86  TSPIIEFGVRNFVDQLIHLQQAFLKKEIMEEDFKQDWKRILDAADDAYRQIKPLKFGQNE 145

Query: 573 EMK-GKGL-GLRITPLPAGHSLG 635
            M    GL  + + P+ AG  +G
Sbjct: 146 TMMFENGLFQVTVCPIRAGKVIG 168


>UniRef50_Q5V0H4 Cluster: MRNA 3'-end processing factor; n=4;
           Halobacteriaceae|Rep: MRNA 3'-end processing factor -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 411

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 28/103 (27%), Positives = 41/103 (39%)
 Frame = +3

Query: 327 SIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL 506
           S DAV++SH    H+G +P  V       PI+ T P Y++      D  + H        
Sbjct: 43  SPDAVVVSHGHLDHVGTIPALVSG-DARPPIHWTPPTYELAMTLARDTLKLHGGTVNCP- 100

Query: 507 FTLDDVDMAFDRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           FT  +V     R+ Q+          +  G  +T   AGH  G
Sbjct: 101 FTETNV----RRVTQVSETHGYRESFEAAGYEVTFYNAGHIPG 139


>UniRef50_A0RY50 Cluster: Exonuclease of the beta-lactamase fold;
           n=1; Cenarchaeum symbiosum|Rep: Exonuclease of the
           beta-lactamase fold - Cenarchaeum symbiosum
          Length = 417

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 16/59 (27%), Positives = 32/59 (54%)
 Frame = +3

Query: 330 IDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDL 506
           +D+++I+H+   H G +P     +  +   YAT P  ++ ++ + D+ +   NV  FDL
Sbjct: 48  VDSIIITHAHLDHSGNVPSMY--ISGNVDTYATAPTLELSKLLIEDMLKIKSNVHIFDL 104


>UniRef50_Q57626 Cluster: Uncharacterized protein MJ0162; n=6;
           Methanococcales|Rep: Uncharacterized protein MJ0162 -
           Methanococcus jannaschii
          Length = 421

 Score = 33.1 bits (72), Expect = 5.8
 Identities = 36/153 (23%), Positives = 67/153 (43%)
 Frame = +3

Query: 177 IIKLHCLSGAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHS 356
           ++K H   G  +    C  ++  + + LLDCG       +     K    ++DAV++SH+
Sbjct: 3   LLKFH--GGCQQIGMSCVEVETQKGRVLLDCGMSPDTGEI----PKVDDKAVDAVIVSHA 56

Query: 357 DPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVSEFDLFTLDDVDMAF 536
              H GA+P+   K      IY T P   +    M+  ++   N+++   +  +D+  A 
Sbjct: 57  HLDHCGAIPFYKFK-----KIYCTHPTADL----MFITWRDTLNLTK--AYKEEDIQHAM 105

Query: 537 DRIVQLKYNQSIEMKGKGLGLRITPLPAGHSLG 635
           + I  L Y +  ++      ++     AGH LG
Sbjct: 106 ENIECLNYYEERQITE---NIKFKFYNAGHILG 135


>UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 207

 Score = 32.7 bits (71), Expect = 7.6
 Identities = 18/52 (34%), Positives = 30/52 (57%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVNSIDAVLISHSDPLHLGAL 380
           CY+L+      ++D G D +  +  IKE   H   I+A+L++H+   H+GAL
Sbjct: 15  CYILKKGTNGIIVDPGGDAELILSIIKE---HHLDINAILLTHAHFDHIGAL 63


>UniRef50_Q8DAV3 Cluster: Rec2-related protein; n=2; Vibrio
           vulnificus|Rep: Rec2-related protein - Vibrio vulnificus
          Length = 749

 Score = 32.7 bits (71), Expect = 7.6
 Identities = 14/26 (53%), Positives = 16/26 (61%)
 Frame = +3

Query: 309 LKRHVNSIDAVLISHSDPLHLGALPY 386
           L R   S+D V+ISH D  H G LPY
Sbjct: 541 LSRGSRSLDGVIISHQDDDHAGGLPY 566


>UniRef50_Q182G4 Cluster: Metallo beta-lactamase superfamily
           lipoprotein; n=2; Clostridium difficile|Rep: Metallo
           beta-lactamase superfamily lipoprotein - Clostridium
           difficile (strain 630)
          Length = 278

 Score = 32.7 bits (71), Expect = 7.6
 Identities = 20/81 (24%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = +3

Query: 174 SIIKLHCLS-GAGEETPPCYVLQIDEFKFLLDCGWDEKFDMVFIKELK-RHVNSIDAVLI 347
           S++ +H +  G G+      ++Q    K +L  G DE  + + I  L+ + + +ID ++ 
Sbjct: 23  SLLSIHMIDVGQGDSI----LVQTPTNKNILIDGGDEDSENIIISYLRQKRIKTIDIIIA 78

Query: 348 SHSDPLHLGALPYAVGKLGLS 410
           +H D  H+G+L   + K  ++
Sbjct: 79  THPDSDHIGSLDNIIKKFNVN 99


>UniRef50_Q54SH0 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 712

 Score = 32.7 bits (71), Expect = 7.6
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = +3

Query: 180 IKLHCLSGAGEETPPCYVLQIDEFKFLLDC 269
           +K+HCLS + +   PC++L+    K LLDC
Sbjct: 1   MKVHCLSQSAQS--PCFLLEYKNVKILLDC 28



 Score = 32.7 bits (71), Expect = 7.6
 Identities = 18/57 (31%), Positives = 31/57 (54%)
 Frame = +3

Query: 324 NSIDAVLISHSDPLHLGALPYAVGKLGLSCPIYATLPVYKMGQMFMYDLYQAHKNVS 494
           ++ID +LIS+   ++  ALP+          IYAT P  ++G++ + +L Q  K  S
Sbjct: 115 STIDMILISNYTNIY--ALPFITEYTNFQGKIYATEPTVQIGKLLLEELVQMDKQYS 169


>UniRef50_A2QCH2 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus niger|Rep: Putative uncharacterized protein
           - Aspergillus niger
          Length = 512

 Score = 32.7 bits (71), Expect = 7.6
 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
 Frame = -2

Query: 472 YKSYMNI-CP-ILYTGRVAYIGQLRPSFPTAYGRAPKCRGSECDISTASIEFTCLLSSLM 299
           ++SY+   C  IL TGR A++G +RP+  T   +    RGS  D +T     +C  S+++
Sbjct: 61  FRSYLGAPCSFILLTGRTAWMGAVRPNLGTTADKDGGRRGSLWDCTTDLRRISCRDSAVL 120


>UniRef50_O29680 Cluster: Putative uncharacterized protein; n=1;
           Archaeoglobus fulgidus|Rep: Putative uncharacterized
           protein - Archaeoglobus fulgidus
          Length = 209

 Score = 32.7 bits (71), Expect = 7.6
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
 Frame = +3

Query: 225 CYVLQIDEFKFLLDCGWDEKFDMVFIKELKRHVN--SIDAVLISHSDPLHLGALPYAVG 395
           CY+L +DE K L+D G D +F    +  LKR+++   +D ++++HS   H  A  +  G
Sbjct: 15  CYLL-LDEKKALIDVGGDIQF---ILNALKRYIDPRELDYIILTHSHYDHAAAAGHFKG 69


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 634,667,529
Number of Sequences: 1657284
Number of extensions: 12723549
Number of successful extensions: 30104
Number of sequences better than 10.0: 209
Number of HSP's better than 10.0 without gapping: 29082
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30000
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 47296372782
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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