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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fmgV10a03r
         (765 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family memb...   253   3e-66
UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family memb...   238   9e-62
UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;...   220   3e-56
UniRef50_Q9S9W2 Cluster: T1J24.9 protein; n=13; Magnoliophyta|Re...   217   2e-55
UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; ...   215   1e-54
UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family memb...   201   2e-50
UniRef50_Q2LE81 Cluster: NADP(H)-dependent retinol dehydrogenase...   155   3e-49
UniRef50_Q22RY4 Cluster: Oxidoreductase, short chain dehydrogena...   190   4e-47
UniRef50_Q4S0T0 Cluster: Chromosome undetermined SCAF14779, whol...   189   8e-47
UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Re...   167   3e-40
UniRef50_UPI0000E81F13 Cluster: PREDICTED: similar to MGC108363 ...   165   1e-39
UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR...   162   1e-38
UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesioc...   156   5e-37
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena...   153   5e-36
UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR...   151   2e-35
UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...   149   1e-34
UniRef50_UPI0001555327 Cluster: PREDICTED: similar to NADPH-depe...   147   3e-34
UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola...   146   4e-34
UniRef50_A3SFH7 Cluster: Oxidoreductase, short-chain dehydrogena...   143   4e-33
UniRef50_Q46NA7 Cluster: Short-chain dehydrogenase/reductase SDR...   141   1e-32
UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...   141   2e-32
UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;...   139   8e-32
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici...   138   1e-31
UniRef50_Q931B7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat...   138   1e-31
UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR...   136   6e-31
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR...   136   6e-31
UniRef50_A0HIJ6 Cluster: Short-chain dehydrogenase/reductase SDR...   136   6e-31
UniRef50_A1SNH6 Cluster: Short-chain dehydrogenase/reductase SDR...   135   1e-30
UniRef50_Q9F5J1 Cluster: SimJ1; n=5; Actinomycetales|Rep: SimJ1 ...   134   2e-30
UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida...   134   3e-30
UniRef50_O61709 Cluster: Putative uncharacterized protein; n=4; ...   134   3e-30
UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   133   5e-30
UniRef50_Q8LFZ4 Cluster: Short chain alcohol dehydrogenase-like;...   133   5e-30
UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh...   132   9e-30
UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR...   132   1e-29
UniRef50_Q0SD55 Cluster: Possible short chain oxidoreductase; n=...   130   3e-29
UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1; ...   130   3e-29
UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR...   130   5e-29
UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR...   129   6e-29
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR...   129   6e-29
UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplan...   129   6e-29
UniRef50_Q93H96 Cluster: Putative oxidoreductase; n=1; Streptomy...   129   9e-29
UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena...   129   9e-29
UniRef50_Q1GNJ7 Cluster: Short-chain dehydrogenase/reductase SDR...   129   9e-29
UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR...   129   9e-29
UniRef50_A0VRR7 Cluster: Short-chain dehydrogenase/reductase SDR...   129   9e-29
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR...   129   9e-29
UniRef50_Q47QE8 Cluster: Probable short-chain type dehydrogenase...   128   1e-28
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR...   128   1e-28
UniRef50_Q2U8E2 Cluster: Dehydrogenases with different specifici...   128   2e-28
UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogena...   127   3e-28
UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o...   126   5e-28
UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   126   5e-28
UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   126   5e-28
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid...   126   6e-28
UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR...   126   6e-28
UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   126   8e-28
UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR...   126   8e-28
UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo...   126   8e-28
UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR...   126   8e-28
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR...   126   8e-28
UniRef50_P55541 Cluster: Uncharacterized short-chain type dehydr...   126   8e-28
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   126   8e-28
UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogena...   125   1e-27
UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   125   1e-27
UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Al...   125   1e-27
UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR...   125   1e-27
UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=...   125   1e-27
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena...   125   1e-27
UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR...   125   1e-27
UniRef50_Q89P11 Cluster: Oxidoreductase; n=8; Proteobacteria|Rep...   125   1e-27
UniRef50_Q1NA92 Cluster: Gluconate 5-dehydrogenase; n=1; Sphingo...   125   1e-27
UniRef50_Q3EBS2 Cluster: Uncharacterized protein At2g29340.1; n=...   125   1e-27
UniRef50_Q08632 Cluster: Short-chain type dehydrogenase/reductas...   125   1e-27
UniRef50_Q7W7A0 Cluster: Probable 3-oxoacyl-[acyl-carrier protei...   124   2e-27
UniRef50_UPI00015BAF2E Cluster: short-chain dehydrogenase/reduct...   124   2e-27
UniRef50_Q93HC0 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...   124   2e-27
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR...   124   2e-27
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac...   124   2e-27
UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...   124   3e-27
UniRef50_Q4JXS5 Cluster: Dehydrogenase related to short-chain al...   124   3e-27
UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...   124   3e-27
UniRef50_A5V310 Cluster: Short-chain dehydrogenase/reductase SDR...   124   3e-27
UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR...   123   4e-27
UniRef50_Q0K243 Cluster: Short chain dehydrogenase; n=3; Cupriav...   123   4e-27
UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR...   123   4e-27
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   123   4e-27
UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/redu...   123   6e-27
UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR...   123   6e-27
UniRef50_P80869 Cluster: Glucose 1-dehydrogenase 2; n=39; Bacill...   123   6e-27
UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r...   122   7e-27
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR...   122   7e-27
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc...   122   1e-26
UniRef50_Q826D4 Cluster: Putative 3-oxoacyl-ACP reductase; n=1; ...   122   1e-26
UniRef50_Q62AB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   122   1e-26
UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR...   122   1e-26
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR...   122   1e-26
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec...   122   1e-26
UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR...   122   1e-26
UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR...   122   1e-26
UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR...   122   1e-26
UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1; Agrobac...   122   1e-26
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta...   122   1e-26
UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R...   122   1e-26
UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   121   2e-26
UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1; ...   121   2e-26
UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain dehydrogena...   121   2e-26
UniRef50_A1RDP9 Cluster: Oxidoreductase, short chain dehydrogena...   121   2e-26
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR...   121   2e-26
UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma...   121   2e-26
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr...   121   2e-26
UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...   120   3e-26
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR...   120   3e-26
UniRef50_Q98H65 Cluster: Short chain dehydrogenase or 3-ketoacyl...   120   4e-26
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR...   120   4e-26
UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   120   4e-26
UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=...   120   5e-26
UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ...   120   5e-26
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR...   120   5e-26
UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductas...   119   7e-26
UniRef50_Q7WM80 Cluster: Probable short chain dehydrogenase; n=1...   119   7e-26
UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain de...   119   7e-26
UniRef50_Q4IUB1 Cluster: Short-chain dehydrogenase/reductase SDR...   119   7e-26
UniRef50_A5VCG8 Cluster: Short-chain dehydrogenase/reductase SDR...   119   7e-26
UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR...   119   7e-26
UniRef50_Q5V3M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   119   7e-26
UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ...   119   9e-26
UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep...   119   9e-26
UniRef50_Q82QS5 Cluster: Putative dehydrogenase; n=1; Streptomyc...   119   9e-26
UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protei...   119   9e-26
UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR...   119   9e-26
UniRef50_A6F000 Cluster: Putative short-chain dehydrogenase/redu...   119   9e-26
UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero...   119   9e-26
UniRef50_Q9HLN6 Cluster: Probable glucose 1-dehydrogenase; n=4; ...   119   9e-26
UniRef50_Q930I9 Cluster: Putative; n=6; Alphaproteobacteria|Rep:...   118   1e-25
UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR...   118   1e-25
UniRef50_Q15TE7 Cluster: Short-chain dehydrogenase/reductase SDR...   118   1e-25
UniRef50_A5VAV2 Cluster: Short-chain dehydrogenase/reductase SDR...   118   1e-25
UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR...   118   1e-25
UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR...   118   1e-25
UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;...   118   1e-25
UniRef50_Q7NFL8 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   118   2e-25
UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR...   118   2e-25
UniRef50_Q1YNT8 Cluster: Oxidoreductase, short chain dehydrogena...   118   2e-25
UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR...   118   2e-25
UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR...   118   2e-25
UniRef50_A3Z051 Cluster: Short-chain dehydrogenase/reductase SDR...   118   2e-25
UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine ...   118   2e-25
UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ...   118   2e-25
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=...   118   2e-25
UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1...   118   2e-25
UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein...   118   2e-25
UniRef50_A7HFH2 Cluster: Short-chain dehydrogenase/reductase SDR...   118   2e-25
UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR...   118   2e-25
UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomyceta...   118   2e-25
UniRef50_Q3IRP1 Cluster: Probable dehydrogenase/ reductase 11; n...   118   2e-25
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K...   117   3e-25
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre...   117   3e-25
UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR...   117   3e-25
UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR...   117   3e-25
UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR...   117   3e-25
UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain de...   117   3e-25
UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR...   117   3e-25
UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter...   117   3e-25
UniRef50_A1VQU4 Cluster: Short-chain dehydrogenase/reductase SDR...   117   3e-25
UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain dehydrogena...   117   3e-25
UniRef50_UPI000038D860 Cluster: COG1028: Dehydrogenases with dif...   117   4e-25
UniRef50_Q9A326 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   117   4e-25
UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...   117   4e-25
UniRef50_Q1DDU7 Cluster: Oxidoreductase, short chain dehydrogena...   117   4e-25
UniRef50_Q126E9 Cluster: Short-chain dehydrogenase/reductase SDR...   117   4e-25
UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...   117   4e-25
UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR...   117   4e-25
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho...   116   5e-25
UniRef50_A5CY54 Cluster: Dehydrogenases with different specifici...   116   5e-25
UniRef50_A4AAT7 Cluster: Short-chain dehydrogenase/reductase SDR...   116   5e-25
UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=...   116   5e-25
UniRef50_Q05528 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   116   5e-25
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O...   116   6e-25
UniRef50_Q57A51 Cluster: Oxidoreductase, short-chain dehydrogena...   116   6e-25
UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;...   116   6e-25
UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR...   116   6e-25
UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR...   116   6e-25
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu...   116   6e-25
UniRef50_A0Z4N7 Cluster: Short chain dehydrogenase; n=2; Bacteri...   116   6e-25
UniRef50_A0TVV4 Cluster: Short-chain dehydrogenase/reductase SDR...   116   6e-25
UniRef50_A0M4X9 Cluster: Short-chain dehydrogenase/reductase fam...   116   6e-25
UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR...   116   8e-25
UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   116   8e-25
UniRef50_A3XJH6 Cluster: D-mannonate oxidoreductase; n=7; Bacter...   116   8e-25
UniRef50_Q3INX8 Cluster: Probable dehydrogenase/ reductase 6; n=...   116   8e-25
UniRef50_Q9EWT4 Cluster: Putative oxidoreductase; n=2; Streptomy...   115   1e-24
UniRef50_Q89EA2 Cluster: Gdh protein; n=3; Bradyrhizobium|Rep: G...   115   1e-24
UniRef50_Q7MYJ9 Cluster: Similar to 3-oxoacyl-acyl carrier prote...   115   1e-24
UniRef50_Q46MD0 Cluster: Short-chain dehydrogenase/reductase SDR...   115   1e-24
UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; ...   115   1e-24
UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str...   115   1e-24
UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier prot...   115   1e-24
UniRef50_Q0RIJ2 Cluster: Putative short chain dehydrogenase/redu...   115   1e-24
UniRef50_Q0LZD3 Cluster: NAD-dependent epimerase/dehydratase:Sho...   115   1e-24
UniRef50_A4FCN3 Cluster: Short-chain dehydrogenase/reductase SDR...   115   1e-24
UniRef50_A0GVX4 Cluster: Short-chain dehydrogenase/reductase SDR...   115   1e-24
UniRef50_Q5V623 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   115   1e-24
UniRef50_Q7D5G1 Cluster: Oxidoreductase, short-chain dehydrogena...   115   1e-24
UniRef50_Q2CJE1 Cluster: Short-chain dehydrogenase/reductase SDR...   115   1e-24
UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR...   115   1e-24
UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT...   114   2e-24
UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain dehydrogena...   114   2e-24
UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholder...   114   2e-24
UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR...   114   2e-24
UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR...   114   2e-24
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;...   114   2e-24
UniRef50_Q3WH17 Cluster: Short-chain dehydrogenase/reductase SDR...   114   3e-24
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...   114   3e-24
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR...   114   3e-24
UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR...   114   3e-24
UniRef50_A4CKB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   114   3e-24
UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR...   114   3e-24
UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR...   114   3e-24
UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll...   113   3e-24
UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR...   113   3e-24
UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like ...   113   3e-24
UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR...   113   3e-24
UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte...   113   3e-24
UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   113   5e-24
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai...   113   5e-24
UniRef50_Q53W82 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   113   5e-24
UniRef50_Q3W9H8 Cluster: Short-chain dehydrogenase/reductase SDR...   113   5e-24
UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma p...   113   5e-24
UniRef50_Q1NCY5 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SK...   113   5e-24
UniRef50_Q1CYK0 Cluster: Putative 3-oxoacyl-(Acyl-carrier-protei...   113   5e-24
UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; ...   113   5e-24
UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR...   113   5e-24
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   113   5e-24
UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   113   6e-24
UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;...   113   6e-24
UniRef50_Q1NH63 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SK...   113   6e-24
UniRef50_A1R613 Cluster: Oxidoreductase, short chain dehydrogena...   113   6e-24
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   112   8e-24
UniRef50_Q39A64 Cluster: Short-chain dehydrogenase/reductase SDR...   112   8e-24
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR...   112   8e-24
UniRef50_Q3W9J0 Cluster: Short-chain dehydrogenase/reductase SDR...   112   8e-24
UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=...   112   8e-24
UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena...   112   8e-24
UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder...   112   8e-24
UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri...   112   8e-24
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena...   112   8e-24
UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR...   112   8e-24
UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR...   112   8e-24
UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain dehydrogena...   112   8e-24
UniRef50_A3PW05 Cluster: Short-chain dehydrogenase/reductase SDR...   112   8e-24
UniRef50_P06234 Cluster: Nodulation protein G; n=71; Bacteria|Re...   112   8e-24
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   112   1e-23
UniRef50_Q9RLV7 Cluster: Diacetyl(Acetoin) reductase; n=4; Lacto...   112   1e-23
UniRef50_Q3W9G7 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_Q0RGH3 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   112   1e-23
UniRef50_Q0BTA5 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   112   1e-23
UniRef50_A7CX22 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_A5FTT3 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_A3K7Y9 Cluster: Oxidoreductase, short-chain dehydrogena...   112   1e-23
UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...   111   1e-23
UniRef50_Q74T42 Cluster: Gluconate 5-dehydrogenase; n=17; Gammap...   111   1e-23
UniRef50_Q1M4Y0 Cluster: Putative short-chain dehydrogenase; n=1...   111   1e-23
UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob...   111   1e-23
UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR...   111   1e-23
UniRef50_A4SZ40 Cluster: Short-chain dehydrogenase/reductase SDR...   111   1e-23
UniRef50_A3U137 Cluster: Short-chain dehydrogenase/reductase SDR...   111   1e-23
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro...   111   1e-23
UniRef50_A0YDQ1 Cluster: Short chain dehydrogenase; n=1; marine ...   111   1e-23
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano...   111   1e-23
UniRef50_Q930L3 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat...   111   2e-23
UniRef50_Q7VV50 Cluster: Probable short chain dehydrogenase; n=1...   111   2e-23
UniRef50_Q1GUS2 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_Q1ARM3 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_Q12AF9 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_Q0RV77 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   111   2e-23
UniRef50_Q0RBT2 Cluster: Short-chain dehydrogenase; n=1; Frankia...   111   2e-23
UniRef50_Q0IBU9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   111   2e-23
UniRef50_A2W8D2 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_A0VRG5 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_UPI000023E6B9 Cluster: hypothetical protein FG02829.1; ...   111   2e-23
UniRef50_Q83HQ5 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   111   2e-23
UniRef50_Q7W5S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   111   2e-23
UniRef50_Q62GI3 Cluster: Oxidoreductase, short-chain dehydrogena...   111   2e-23
UniRef50_Q46MP7 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_A3XEC4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   111   2e-23
UniRef50_Q4J702 Cluster: Oxidoreductase; n=2; Sulfolobus|Rep: Ox...   111   2e-23
UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=...   111   2e-23
UniRef50_P50200 Cluster: NADP-dependent 7-alpha-hydroxysteroid d...   111   2e-23
UniRef50_UPI0000E48942 Cluster: PREDICTED: hypothetical protein;...   110   3e-23
UniRef50_Q629N6 Cluster: Putative polyketide synthase; n=11; Bur...   110   3e-23
UniRef50_Q3IVC8 Cluster: Short-chain alcohol dehydrogenases; n=2...   110   3e-23
UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR...   110   3e-23
UniRef50_A6D230 Cluster: Short-chain dehydrogenase; n=1; Vibrio ...   110   3e-23
UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR...   110   3e-23
UniRef50_Q97UA4 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...   110   3e-23
UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M...   110   3e-23
UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc...   110   4e-23
UniRef50_Q2K0D6 Cluster: Probable oxidoreductase protein, dehydr...   110   4e-23
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill...   110   4e-23
UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_Q18QN3 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_Q0FPS1 Cluster: Probable dehydrogenase; n=1; Roseovariu...   110   4e-23
UniRef50_P95719 Cluster: Ata4 protein; n=2; Actinomycetales|Rep:...   110   4e-23
UniRef50_O85961 Cluster: Dihydroxy cyclohexadiene carboxylate de...   110   4e-23
UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...   110   4e-23
UniRef50_A3IAI0 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_A0GFV9 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|R...   109   6e-23
UniRef50_Q8U6I6 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   109   6e-23
UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR...   109   6e-23
UniRef50_Q3A5I8 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...   109   6e-23
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=...   109   6e-23
UniRef50_Q11EZ4 Cluster: Short-chain dehydrogenase/reductase SDR...   109   6e-23
UniRef50_Q01PN9 Cluster: Short-chain dehydrogenase/reductase SDR...   109   6e-23
UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR...   109   6e-23
UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Ac...   109   6e-23
UniRef50_A3VK91 Cluster: Putative 3-ketoacyl-CoA reductase; n=1;...   109   6e-23
UniRef50_A3SDF7 Cluster: Short-chain dehydrogenase/reductase SDR...   109   6e-23
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR...   109   6e-23
UniRef50_Q8YDW1 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT...   109   7e-23
UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specifici...   109   7e-23
UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena...   109   7e-23
UniRef50_Q883G7 Cluster: Oxidoreductase, short chain dehydrogena...   109   7e-23
UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep...   109   7e-23
UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ...   109   7e-23
UniRef50_Q1IKU0 Cluster: Short-chain dehydrogenase/reductase SDR...   109   7e-23
UniRef50_Q142X0 Cluster: Short-chain dehydrogenase/reductase SDR...   109   7e-23
UniRef50_A5FZN0 Cluster: Short-chain dehydrogenase/reductase SDR...   109   7e-23
UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR...   109   7e-23
UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR...   109   7e-23
UniRef50_Q8ZVW5 Cluster: Short chain dehydrogenase family; n=3; ...   109   7e-23
UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;...   109   1e-22
UniRef50_Q1NAB3 Cluster: Short-chain dehydrogenase/reductase SDR...   109   1e-22
UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR...   109   1e-22
UniRef50_A1W2L0 Cluster: Short-chain dehydrogenase/reductase SDR...   109   1e-22
UniRef50_A1BBU8 Cluster: Short-chain dehydrogenase/reductase SDR...   109   1e-22
UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   109   1e-22
UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo...   109   1e-22
UniRef50_P33368 Cluster: Uncharacterized oxidoreductase yohF; n=...   109   1e-22
UniRef50_P0AET9 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...   109   1e-22
UniRef50_P16543 Cluster: Granaticin polyketide synthase putative...   109   1e-22
UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ...   108   1e-22
UniRef50_Q3WC70 Cluster: Short-chain dehydrogenase/reductase SDR...   108   1e-22
UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro...   108   1e-22
UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR...   108   1e-22
UniRef50_Q11AM7 Cluster: Short-chain dehydrogenase/reductase SDR...   108   1e-22
UniRef50_Q0JZY8 Cluster: 3-Oxoacyl-[acyl-carrier-protein] reduct...   108   1e-22
UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus oeni...   108   1e-22
UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ...   108   1e-22
UniRef50_A1UPQ1 Cluster: Short-chain dehydrogenase/reductase SDR...   108   1e-22
UniRef50_A0R386 Cluster: Dehydrogenase/reductase SDR family prot...   108   1e-22
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   108   1e-22
UniRef50_P0A2D1 Cluster: Oxidoreductase ucpA; n=21; Bacteria|Rep...   108   1e-22
UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...   108   2e-22
UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta...   108   2e-22
UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR...   108   2e-22
UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill...   108   2e-22
UniRef50_A5V6V5 Cluster: Short-chain dehydrogenase/reductase SDR...   108   2e-22
UniRef50_A1SG64 Cluster: Short-chain dehydrogenase/reductase SDR...   108   2e-22
UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   108   2e-22
UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p...   108   2e-22
UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   107   2e-22
UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ...   107   2e-22
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR...   107   2e-22
UniRef50_A0GP81 Cluster: Short-chain dehydrogenase/reductase SDR...   107   2e-22
UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici...   107   2e-22
UniRef50_A7D6X0 Cluster: Short-chain dehydrogenase/reductase SDR...   107   2e-22
UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap...   107   3e-22
UniRef50_Q7WPV2 Cluster: Short chain dehydrogenase; n=2; Bordete...   107   3e-22
UniRef50_Q7ND89 Cluster: Gll4347 protein; n=3; Cyanobacteria|Rep...   107   3e-22
UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   107   3e-22
UniRef50_Q62E80 Cluster: Acetoacetyl-CoA reductase; n=60; Proteo...   107   3e-22
UniRef50_Q53W85 Cluster: Oxidoreductase, short-chain dehydrogena...   107   3e-22
UniRef50_Q4FL45 Cluster: Short chain dehydrogenase; n=2; Bacteri...   107   3e-22
UniRef50_Q393N0 Cluster: Short-chain dehydrogenase/reductase SDR...   107   3e-22
UniRef50_Q0AHP0 Cluster: Short-chain dehydrogenase/reductase SDR...   107   3e-22
UniRef50_A3NPI1 Cluster: Multi-domain beta keto-acyl synthase; n...   107   3e-22
UniRef50_A1UJK1 Cluster: Short-chain dehydrogenase/reductase SDR...   107   3e-22
UniRef50_A5A7R3 Cluster: 17beta-hydroxysteroid dehydrogenase typ...   107   3e-22
UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   107   3e-22
UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bact...   107   3e-22
UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   107   4e-22
UniRef50_Q67MW8 Cluster: Short chain dehydrogenase; n=1; Symbiob...   107   4e-22
UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR...   107   4e-22
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1...   107   4e-22
UniRef50_Q1GNJ8 Cluster: Short-chain dehydrogenase/reductase SDR...   107   4e-22
UniRef50_Q0S4C7 Cluster: Reductase; n=4; Bacteria|Rep: Reductase...   107   4e-22
UniRef50_A7HBZ0 Cluster: Short-chain dehydrogenase/reductase SDR...   107   4e-22
UniRef50_A3VAL9 Cluster: Oxidoreductase, short-chain dehydrogena...   107   4e-22
UniRef50_A3J7V6 Cluster: Short-chain dehydrogenase/reductase SDR...   107   4e-22
UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   107   4e-22
UniRef50_Q5P5I4 Cluster: (S)-1-Phenylethanol dehydrogenase; n=1;...   106   5e-22
UniRef50_Q39MZ0 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact...   106   5e-22
UniRef50_Q1LDG6 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_Q1GUT4 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena...   106   5e-22
UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re...   106   5e-22
UniRef50_A3Q454 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_A1WGL6 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_A1WEP3 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula...   106   5e-22
UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo...   106   5e-22
UniRef50_Q98C97 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...   106   7e-22
UniRef50_Q8FV67 Cluster: 2-deoxy-d-gluconate 3-dehydrogenase, pu...   106   7e-22
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...   106   7e-22
UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R...   106   7e-22
UniRef50_Q39DX6 Cluster: Short-chain dehydrogenase/reductase SDR...   106   7e-22
UniRef50_Q03ND1 Cluster: 3-oxoacyl-acyl carrier protein reductas...   106   7e-22
UniRef50_A7NQP2 Cluster: Short-chain dehydrogenase/reductase SDR...   106   7e-22
UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR...   106   7e-22
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR...   106   7e-22
UniRef50_Q8ZYG0 Cluster: Short chain dehydrogenase; n=2; Pyrobac...   106   7e-22
UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   106   7e-22
UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   106   7e-22
UniRef50_Q64BR1 Cluster: 3-oxoacyl-acyl carrier protein reductas...   106   7e-22
UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   106   7e-22
UniRef50_Q5BLE6 Cluster: Zgc:113054; n=8; Euteleostomi|Rep: Zgc:...   105   9e-22
UniRef50_Q8EMP9 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...   105   9e-22
UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   105   9e-22
UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteri...   105   9e-22
UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_Q2S4K7 Cluster: Oxidoreductase, short chain dehydrogena...   105   9e-22
UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrob...   105   9e-22
UniRef50_Q3WAU6 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   105   9e-22
UniRef50_Q0LZB7 Cluster: NAD-dependent epimerase/dehydratase:Sho...   105   9e-22
UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_A6UHB9 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...   105   9e-22
UniRef50_A4XF74 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_A3K7W9 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   105   9e-22
UniRef50_A1TC74 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR...   105   9e-22
UniRef50_A1CV74 Cluster: Gluconate 5-dehydrogenase; n=2; Trichoc...   105   9e-22
UniRef50_Q9BY49 Cluster: Peroxisomal trans-2-enoyl-CoA reductase...   105   9e-22
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte...   105   9e-22
UniRef50_Q89FM8 Cluster: Dehydrogenase; n=1; Bradyrhizobium japo...   105   1e-21
UniRef50_Q89CB1 Cluster: Bll7886 protein; n=8; Bradyrhizobiaceae...   105   1e-21
UniRef50_Q7VZN8 Cluster: Short-chain dehydrogenase; n=3; Bordete...   105   1e-21
UniRef50_Q7VSG1 Cluster: Gluconate 5-dehydrogenase; n=11; Proteo...   105   1e-21
UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   105   1e-21
UniRef50_Q5LMF4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   105   1e-21
UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_Q1AT77 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_A5P5M1 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_A3PQM4 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_A1WRF5 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_Q8K9J5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   105   1e-21
UniRef50_Q9RJU5 Cluster: Probable oxidoreductase; n=1; Streptomy...   105   2e-21
UniRef50_Q390H0 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_Q2T2R4 Cluster: Polyketide synthase, putative; n=1; Bur...   105   2e-21
UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_A5FBH9 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_A1UGA4 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas...   105   2e-21
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_Q92506 Cluster: Estradiol 17-beta-dehydrogenase 8; n=38...   105   2e-21
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b...   105   2e-21
UniRef50_Q8U673 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...   104   2e-21
UniRef50_Q46N54 Cluster: NAD-dependent epimerase/dehydratase:Sho...   104   2e-21
UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_Q9EX74 Cluster: SDR-like enzyme; n=1; Rhodococcus eryth...   104   2e-21
UniRef50_Q3E250 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho...   104   2e-21
UniRef50_Q12BL9 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_A5WD60 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_A4FJJ0 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_A0TW22 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   104   3e-21
UniRef50_Q7NLK9 Cluster: Glucose 1-dehydrogenase; n=18; Bacteria...   104   3e-21
UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_Q3VYE5 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_Q1MCI6 Cluster: Putative short-chain dehydrogenase/redu...   104   3e-21
UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_Q03U43 Cluster: Short-chain alcohol dehydrogenase; n=4;...   104   3e-21
UniRef50_A5UX97 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_A3JIH3 Cluster: Acetoacetyl-CoA reductase; n=3; Gammapr...   104   3e-21
UniRef50_A1WLZ9 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_A0QYY4 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   104   3e-21
UniRef50_Q397Q8 Cluster: Short-chain dehydrogenase/reductase SDR...   103   4e-21
UniRef50_Q44MJ4 Cluster: Short-chain dehydrogenase/reductase SDR...   103   4e-21
UniRef50_Q1YNT9 Cluster: Putative 3-ketoacyl-CoA reductase; n=2;...   103   4e-21

>UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family member
           4; n=11; Coelomata|Rep: Dehydrogenase/reductase SDR
           family member 4 - Oryctolagus cuniculus (Rabbit)
          Length = 260

 Score =  253 bits (620), Expect = 3e-66
 Identities = 121/232 (52%), Positives = 160/232 (68%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+RL  +GA VVI SRK+ NV +AV +L++EG++V G VCHV   E R RL   A + 
Sbjct: 29  AIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCHVGKAEDRERLVATALNL 88

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GG+DIL            ++D  E+VWDKI D+NVK+  L+ K   PE+ KRGGGS+V 
Sbjct: 89  HGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMTKAVVPEMEKRGGGSVVI 148

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++SIAA+ P   LG Y VSKT L+GLTK +A E   +NIRVNC+APG++ T F+ A+   
Sbjct: 149 VASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNCLAPGLIKTSFSKALWED 208

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
           +A  E  +  + ++R G+PEE AG V+FL S+DASYITGETVVVAGGAP+RL
Sbjct: 209 KAQEENIIQKLRIRRLGKPEECAGIVSFLCSEDASYITGETVVVAGGAPSRL 260


>UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family member
           4; n=9; Eutheria|Rep: Dehydrogenase/reductase SDR family
           member 4 - Sus scrofa (Pig)
          Length = 260

 Score =  238 bits (583), Expect = 9e-62
 Identities = 116/232 (50%), Positives = 153/232 (65%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+RL  +GA VV+ SRK+ NV + V +L+ EG++V G VCHV   E R RL  +A + 
Sbjct: 29  AIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVNL 88

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GGVDIL           +I+D  E+VWDKI  VNVK++ L+ K   PE+ KRGGGS++ 
Sbjct: 89  HGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEMEKRGGGSVLI 148

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS+ AY P   LG Y VSKT LLGLTK +A E    NIRVNC+APG++ T F+  +   
Sbjct: 149 VSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMD 208

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
           +A  E    ++ ++R G PE+ AG V+FL S+DASYITGETVVV GG  +RL
Sbjct: 209 KARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVVVGGGTASRL 260


>UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;
           n=4; Bilateria|Rep: Dehydrogenases, short chain protein
           13 - Caenorhabditis elegans
          Length = 257

 Score =  220 bits (538), Expect = 3e-56
 Identities = 107/232 (46%), Positives = 147/232 (63%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIAK+LG+ GASVV+CSRK+ NV +AV +LR E I   G   HV N   R +L +    +
Sbjct: 26  AIAKQLGAAGASVVVCSRKKENVDEAVAALRLENIDAHGTTAHVGNKSDRTKLIDFTLDR 85

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           F  +DIL            ++   +  WDK+ D+NVKS++ L KEA P L   G G++VF
Sbjct: 86  FTKLDILVSNAAVNPHYGDLMKVTDSQWDKLLDLNVKSAFELTKEAVPHLEASGRGNVVF 145

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS+A Y P   +GAY V KTTL GL+K++A      NIRVN +APGI+ T F+  + + 
Sbjct: 146 VSSVAGYSPMNEIGAYSVMKTTLTGLSKSLALNLARRNIRVNSIAPGIIQTDFSQVLFSD 205

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
           E+  +K LS +  +RFG P+E A AVAFL SD+ASYI+GET+ + GG  AR+
Sbjct: 206 ESEKQKWLSQIAQRRFGDPDECAEAVAFLVSDEASYISGETIGINGGMHARI 257


>UniRef50_Q9S9W2 Cluster: T1J24.9 protein; n=13; Magnoliophyta|Rep:
           T1J24.9 protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 254

 Score =  217 bits (531), Expect = 2e-55
 Identities = 116/231 (50%), Positives = 149/231 (64%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           I +R G EGASVV+ SRK++NV +AV  L+S+GI   G+VCHV+N +HRR L E    K+
Sbjct: 27  ITERFGLEGASVVVSSRKQANVDEAVAKLKSKGIDAYGIVCHVSNAQHRRNLVEKTVQKY 86

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +DI+            IL + E V DK++++NVKSS LL ++  P L K  G S++FI
Sbjct: 87  GKIDIVVCNAAANPSTDPILSSKEAVLDKLWEINVKSSILLLQDMAPHLEK--GSSVIFI 144

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +SIA + P   +  YGV+KT LLGLTKA+A E   +  RVN VAPG V T FAS IT S 
Sbjct: 145 TSIAGFSPQGAMAMYGVTKTALLGLTKALAAEMAPDT-RVNAVAPGFVPTHFASFITGSS 203

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
              E       L R G   ++A A AFLASDD+SYITGET+VVAGG P+RL
Sbjct: 204 EVREGIEEKTLLNRLGTTGDMAAAAAFLASDDSSYITGETLVVAGGMPSRL 254


>UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 260

 Score =  215 bits (525), Expect = 1e-54
 Identities = 105/236 (44%), Positives = 160/236 (67%), Gaps = 4/236 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATS 587
           AIA+RL  EGASVVI SR + NV +A++ L+++G+T V G+  H+A+ + +++L +    
Sbjct: 25  AIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQ 84

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           KFG ++IL            IL+  +QVWDK+F+VNVK+ + + K  +P + K GGG+I+
Sbjct: 85  KFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAII 144

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           F +S +AY+    + AYGV+KTTL+GLT+A+A     +NIRVN +APG++ TK +  + +
Sbjct: 145 FNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWD 204

Query: 226 SEAGAEKSLSN---VPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
               AEK L++   + L R G P++ AG VA+LASDD+SYITGE +++AGG  ARL
Sbjct: 205 GGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGVQARL 260


>UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family member
           2; n=64; Eumetazoa|Rep: Dehydrogenase/reductase SDR
           family member 2 - Homo sapiens (Human)
          Length = 258

 Score =  201 bits (490), Expect = 2e-50
 Identities = 105/226 (46%), Positives = 137/226 (60%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+RL  +GA VVI SRK+ NV +A+  L+ EG++V G+VCHV   E R +L   A   
Sbjct: 29  AIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEH 88

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GGVD L           S L T EQ+WDKI  VNVKS  LL  +  P +  R G +++ 
Sbjct: 89  CGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG-AVIL 147

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SSIAAY P   LG Y VSKT LLGLT+ +A E   ++IRVNCV PGI+ T F+     +
Sbjct: 148 VSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGN 207

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
           E+  +    +  L+R G  E+ AG V+FL S DASY+ GE + VAG
Sbjct: 208 ESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 253


>UniRef50_Q2LE81 Cluster: NADP(H)-dependent retinol
           dehydrogenase/reductase B1 isoform; n=14; Eutheria|Rep:
           NADP(H)-dependent retinol dehydrogenase/reductase B1
           isoform - Homo sapiens (Human)
          Length = 244

 Score =  155 bits (375), Expect(2) = 3e-49
 Identities = 73/140 (52%), Positives = 95/140 (67%)
 Frame = -3

Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
           D+NVK+  L+ K   PE+ KRGGGS+V +SSIAA+ P+     Y VSKT LLGLTK +A 
Sbjct: 105 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 164

Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASD 128
           E    NIRVNC+APG++ T F+  +   +   E     + ++R G PE+ AG V+FL S+
Sbjct: 165 ELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 224

Query: 127 DASYITGETVVVAGGAPARL 68
           DASYITGETVVV GG P+RL
Sbjct: 225 DASYITGETVVVGGGTPSRL 244



 Score = 63.7 bits (148), Expect(2) = 3e-49
 Identities = 32/59 (54%), Positives = 42/59 (71%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           AIA+RL  +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV   E R RL  VAT+
Sbjct: 47  AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERL--VATT 103


>UniRef50_Q22RY4 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=2;
           Oligohymenophorea|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Tetrahymena
           thermophila SB210
          Length = 255

 Score =  190 bits (462), Expect = 4e-47
 Identities = 92/231 (39%), Positives = 144/231 (62%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           I+KRL  EGA+V+I SR + NV +AV+ +R  G   EG+VCH    E R++L + A  KF
Sbjct: 27  ISKRLALEGATVIINSRSQKNVTEAVEMIRQLGGKAEGLVCHAGKPEDRQKLLQFAKDKF 86

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           GGVDIL           +  DT EQ  DK++++N K    L ++A P +  R G +++ +
Sbjct: 87  GGVDILIPNAAVSTFMGAFTDTPEQAMDKMYEINFKGVLFLVRDALPFMRGRKGANVILV 146

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           SS++ Y+    +G YG++KT +L + K +A E   + IRVNCVAPG++ TKF+ A+    
Sbjct: 147 SSLSGYEQENLIGFYGITKTMVLVMNKLLARELQSDGIRVNCVAPGVIKTKFSEALWKDR 206

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
              ++++ +  + R G PE+++ AVA+LAS++AS+ITGE + +AG    RL
Sbjct: 207 --EQQTILSEGVSRLGVPEDVSSAVAYLASEEASFITGECLAMAGKPLVRL 255


>UniRef50_Q4S0T0 Cluster: Chromosome undetermined SCAF14779, whole
           genome shotgun sequence; n=4; Bilateria|Rep: Chromosome
           undetermined SCAF14779, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 295

 Score =  189 bits (460), Expect = 8e-47
 Identities = 91/176 (51%), Positives = 119/176 (67%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ LGS GA VV+ SR+++NV KAV  LRS+ I V G  C+V   E R +L + A  +
Sbjct: 42  AAAQALGSRGAHVVVSSRRQANVDKAVALLRSQDIQVTGTTCNVGKGEDREKLIQTALDR 101

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GG+DIL           + LD+ E+VWDKI  VNVKS++LL K   P + KRGGG+I+F
Sbjct: 102 CGGIDILVSNAAVNPFFGNTLDSTEEVWDKILSVNVKSAFLLTKLVVPHMEKRGGGNIIF 161

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           +SS+ AYQP + LG Y VSKT LLGLTK +A E    NIRVNCVAPG++ T+F++A
Sbjct: 162 VSSVGAYQPMQGLGPYCVSKTALLGLTKVLAPELAQSNIRVNCVAPGVIKTRFSAA 217


>UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Rep:
           Blr1409 protein - Bradyrhizobium japonicum
          Length = 266

 Score =  167 bits (406), Expect = 3e-40
 Identities = 85/225 (37%), Positives = 131/225 (58%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A+ L   GA VV+ SRK     +    + + G     + C++A       L   AT+ +G
Sbjct: 36  AELLARLGAKVVVSSRKADACKEVADGINAAGGDAIVIPCNIARKAEVEALIAGATTHYG 95

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
            +DIL            +LD  ++ +DKI   NVKS+  L+  A P++ +RG GS++ IS
Sbjct: 96  KIDILVCNAAVNPYYGPLLDITDEAFDKIMGSNVKSNIWLSALAIPQMAERGNGSVIIIS 155

Query: 397 SIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEA 218
           SI   + +  +GAYG+SK     L +++A E   + +RVNC+APG+V T FA A+   EA
Sbjct: 156 SIGGLRGSTVIGAYGISKAADFALCRSLAGEWGPKGVRVNCIAPGLVKTDFARALWEDEA 215

Query: 217 GAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             ++  +  PL+R G P+EIAGAVA+LASD +S++TG+T+V+ GG
Sbjct: 216 LLKRRTATTPLRRIGEPDEIAGAVAYLASDASSFMTGQTIVIDGG 260


>UniRef50_UPI0000E81F13 Cluster: PREDICTED: similar to MGC108363
           protein; n=2; Gallus gallus|Rep: PREDICTED: similar to
           MGC108363 protein - Gallus gallus
          Length = 310

 Score =  165 bits (400), Expect = 1e-39
 Identities = 76/176 (43%), Positives = 112/176 (63%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A+RLG  GA V++ SR++ NV  AVQ LR++G+ V GVVCHV   + R+ L + A   
Sbjct: 42  AVAQRLGEAGARVLLSSRRQPNVDAAVQKLRAQGLEVSGVVCHVGQPQDRQHLVQTALDT 101

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +DIL           S L+ +E  W+KIF VNV ++ +L K   P + KRGGG++V 
Sbjct: 102 YGAIDILVSNAAVNPVMGSTLEVEESAWEKIFQVNVTAAAMLVKLVVPHMEKRGGGAVVL 161

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           ++S+A + P   LG Y VSKT+LLGL   +A E     +R+N VAPG++ T+F++A
Sbjct: 162 VTSVAGFMPFPALGPYSVSKTSLLGLVNVLAPELRARGVRINAVAPGLIPTRFSAA 217


>UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Herpetosiphon aurantiacus ATCC 23779
          Length = 257

 Score =  162 bits (393), Expect = 1e-38
 Identities = 78/228 (34%), Positives = 129/228 (56%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+     GA VV+C+RK  ++     S+   G T   + CH    E  + +     ++
Sbjct: 23  AIAQHFAQAGAKVVVCARKLESLQTVADSINQAGGTALAMACHTGKPEQVQAVVAQTLAE 82

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +DI+            +L++D   WDK ++VNVK  + L + A   +  +GGGSI+ 
Sbjct: 83  WGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYFWLIQAAAEAMQAQGGGSIIN 142

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S+A  QP   +G Y +SK  ++ +TK +A E    NIRVN +APG++ TKF+SA+ ++
Sbjct: 143 VASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIRVNALAPGLIKTKFSSALWDN 202

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           E   +K ++  PL R G  +E+A A  +LASD A++ TG  + + GG+
Sbjct: 203 EDLNQKIVAGTPLGRIGTVDEVAAAALYLASDAAAFTTGTVITMDGGS 250


>UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1;
           Plesiocystis pacifica SIR-1|Rep: Short chain
           dehydrogenase - Plesiocystis pacifica SIR-1
          Length = 267

 Score =  156 bits (379), Expect = 5e-37
 Identities = 86/228 (37%), Positives = 122/228 (53%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATS 587
           A A  L   GA VVI SRK   + +A   +R + G  V  V  H  + E  +R+      
Sbjct: 30  ATATALSRAGAKVVIASRKPEPLEQAAAHIREQTGGEVLAVPAHTGDDEAVQRVVAKTVE 89

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
            FGGVD+L            I+ + +  WDK +DVNVK  + + K   PE+  RGGG I+
Sbjct: 90  AFGGVDVLVNNAATNPHFGPIMSSQDSHWDKTYDVNVKGYFRMVKACVPEMQTRGGGRII 149

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            I+S+A  +    +G Y VSK  +  LT+ +A E     I VN + PG V TKF+SAI  
Sbjct: 150 NIASVAGRRVQPGMGVYCVSKAAVCMLTQVLAVELADAKINVNALTPGFVKTKFSSAIWG 209

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +EA  +  L ++P  R  +PEEIA  + FLASD +S++TG  + + GG
Sbjct: 210 NEAIGKAVLKSIPQHRMAQPEEIANLIQFLASDASSFVTGSIIDIDGG 257


>UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=3;
           Bacteroidetes|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Polaribacter
           dokdonensis MED152
          Length = 257

 Score =  153 bits (371), Expect = 5e-36
 Identities = 78/227 (34%), Positives = 114/227 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIAK L  +GA VVI SR +    +  +  + +G+   G+ CH+   + R+ L +     
Sbjct: 26  AIAKGLAEQGAQVVISSRNQEACDEVAKEFKEQGLDTIGIACHIGKEDQRKNLVDKTIES 85

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL            I +   +++DKI DVNVK+ W L+    P       GSI+ 
Sbjct: 86  FGRIDILVNNAAINPVFGPIEEVSPEIFDKIMDVNVKAPWSLSNLVLPHFQTNKNGSIIN 145

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I+S+ A  P   LG Y  SK  +L LTK  A E     ++ N + PG++ TKF++A+  +
Sbjct: 146 IASVEALTPGLGLGIYSTSKAAILMLTKNQAKEWGKYGVKANAICPGLIKTKFSAALWQN 205

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E    K    +P  R G PEE+ G    LASD  +Y+TG      GG
Sbjct: 206 EKILSKVEKALPSSRMGMPEEMVGLACLLASDAGNYMTGGVYTADGG 252


>UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=33; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 254

 Score =  151 bits (366), Expect = 2e-35
 Identities = 82/226 (36%), Positives = 118/226 (52%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IAK L  +GA V++ SRK  +       + + G   E + CHV   +     FE    K 
Sbjct: 26  IAKLLAEQGAHVIVSSRKLDDCQAVADEIVAAGGRAEALACHVGRLDDIAATFEHIRGKH 85

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +DIL            ILDTD   ++K  DVN++  + ++ EA   +   GGG+IV  
Sbjct: 86  GRLDILVNNAAANPYFGHILDTDLAAYEKTVDVNIRGYFFMSVEAGKLMKANGGGAIVNT 145

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +S+ A QP +  G Y ++K  ++ +TKA A E     IRVN + PG+  TKFA A+   +
Sbjct: 146 ASVNALQPGDRQGIYSITKAAVVNMTKAFAKECGPLGIRVNALLPGLTKTKFAGALFADK 205

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              E  +  +PL+R   P E+AG V +L SD ASY  GE +VV GG
Sbjct: 206 DIYETWMGKIPLRRHAEPREMAGTVLYLVSDAASYTNGECIVVDGG 251


>UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Leptospira interrogans
          Length = 256

 Score =  149 bits (360), Expect = 1e-34
 Identities = 81/235 (34%), Positives = 123/235 (52%), Gaps = 4/235 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+ K   S+G  VV C R+     K    +R+EG  V  VVC V + E  +++ + A  K
Sbjct: 22  AVVKEFVSKGVKVVFCGRRLEEGKKLESEIRAEGGDVYFVVCDVTSGEQVKKVVDAALEK 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D              + +  E VWDK+ +VN+K +WL  K   PE++K GGG +V 
Sbjct: 82  FGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLKGTWLSMKYQIPEMIKMGGGVVVN 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA---I 233
           +SSI+       +  Y  +K  ++GLTK+ A E   +NIR+N + PG V T+       +
Sbjct: 142 VSSISGINGVVGINPYAAAKHGVVGLTKSAALEYAKKNIRINAICPGAVKTEILDELFHL 201

Query: 232 TNSEAGAEKSLSNV-PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
                 AE+ L  + P+ R   PEEI+  V +L S+D+S+ITG  + V GG  A+
Sbjct: 202 AKDPVEAERQLVKLHPIHRIASPEEISKTVLWLCSEDSSFITGTAIPVDGGYSAK 256


>UniRef50_UPI0001555327 Cluster: PREDICTED: similar to
           NADPH-dependent retinol dehydrogenase/reductase,
           partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           similar to NADPH-dependent retinol
           dehydrogenase/reductase, partial - Ornithorhynchus
           anatinus
          Length = 496

 Score =  147 bits (356), Expect = 3e-34
 Identities = 85/222 (38%), Positives = 126/222 (56%), Gaps = 3/222 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A+RLG +GA VV+ SRK+ NV +AV +L++EG++V G VCHV   E R RL   A  +
Sbjct: 33  AVARRLGRDGAHVVLSSRKQKNVDRAVAALQAEGLSVSGTVCHVGKAEDRERLVATALER 92

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +GG+DIL           ++LD  E+VWDKI D+NVK++ LL K   PE+ KRGGGS++ 
Sbjct: 93  YGGIDILVSNAAVNPFFGNLLDASEEVWDKILDINVKATVLLVKAVVPEMEKRGGGSVII 152

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLL---GLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           +SSIAA+ P  PL ++    T+LL    + + ++   + +  RV          KF   +
Sbjct: 153 VSSIAAFSPL-PLFSFSPFSTSLLFRYSIRRCLSQGALQQQHRVKLETK---PKKFEERV 208

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITG 107
             SE   ++ L    L + G  EE+    A L +D A  + G
Sbjct: 209 LGSEV-LDQVLHT--LSKSGSLEELVLDNAGLKTDFAQKLAG 247


>UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola
           batsensis HTCC2597|Rep: Probable dehydrogenase -
           Oceanicola batsensis HTCC2597
          Length = 254

 Score =  147 bits (355), Expect = 4e-34
 Identities = 76/227 (33%), Positives = 122/227 (53%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A+     GA VV+ SRK        +++R +G     V CH+ N E  + L +    +
Sbjct: 24  AMAEMFAEAGARVVVSSRKREACKPVAEAIREKGGEAIVVPCHIGNPEDLQNLVDTTIRE 83

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D+L            + D D+ V+DK+   NV++   + K   P + + GGG++V 
Sbjct: 84  WGRIDVLVPNAAINPVYGPMQDLDDAVFDKMLVTNVRTINTMCKMVLPRMAENGGGAVVI 143

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS+AA + +  LGAYGV+K     + +A+A E   +NIRVN + PG++ T FA A+   
Sbjct: 144 ISSVAAIKGSTTLGAYGVTKAADAAVARALALEWGPQNIRVNAIGPGLIKTDFARALWED 203

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               E+  S  PL+R G  +EIAG   +LAS  + Y+ G+ ++  GG
Sbjct: 204 PDRIERINSANPLRRMGTVDEIAGTALWLASPMSGYVNGQLIIADGG 250


>UniRef50_A3SFH7 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=2;
           Sulfitobacter|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Sulfitobacter
           sp. EE-36
          Length = 255

 Score =  143 bits (347), Expect = 4e-33
 Identities = 75/229 (32%), Positives = 126/229 (55%), Gaps = 1/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGI-TVEGVVCHVANHEHRRRLFEVATS 587
           A+AK L   GA+VVI +RK+  +  A   + + G     GV C+V   E  + L +    
Sbjct: 23  AMAKGLAEHGATVVISARKQDQLDAAAAEINALGKGKAFGVACNVGYKEQLQALVDETHK 82

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
             G +DI+              +  +  ++K  + NV S+  LA+   P+++++G GS+ 
Sbjct: 83  LAGKIDIVIGNAGVNPYYGPTSEIPDDAYEKTMNANVLSNLWLAQMVAPDMIEKGAGSMA 142

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           F SSI A++P+  LG YG+SK  L+GL + +A E   + +R N + PG+V T+FA  + +
Sbjct: 143 FTSSIGAFKPSVMLGTYGMSKLALIGLVRNLAAEFGPKGLRFNAICPGLVKTEFARELWD 202

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           +    ++  + +PL+R G  E+ AG   FLASD + Y+TG+ + V GG+
Sbjct: 203 NPDVEKRIKNEIPLRRLGEAEDFAGLAVFLASDASRYMTGQALTVCGGS 251


>UniRef50_Q46NA7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Ralstonia eutropha JMP134|Rep: Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 255

 Score =  141 bits (342), Expect = 1e-32
 Identities = 76/227 (33%), Positives = 123/227 (54%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+ L   GA VV+ S  +S+   A   L SEG  V+G+ C + N ++ +   E +   
Sbjct: 25  AIARGLAQCGAQVVVSSHLQSDTDSAASLLASEGFDVKGIPCDITNLDNVKNFSEESKRA 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG VDI+            I +TD  + D +    V+++ +L ++  PE+ +R  GS++ 
Sbjct: 85  FGHVDIVVCHAAGPVPVGPIAETDIDLLDSLLLTTVRNNLVLIRQFLPEMAERRYGSVLM 144

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            SSIA+ + +  LGAYG +K  L G+ ++IA E    NIR N +AP +V T F+  + ++
Sbjct: 145 TSSIASERASPALGAYGAAKAALNGVVRSIAAEWGQWNIRANALAPSMVRTAFSQVMLST 204

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               +   +  P  R   P++I GA   LAS   SYI+G+T+++ GG
Sbjct: 205 PDAVKAMAAKSPSNRIAEPDDIVGAAILLASPAGSYISGQTLLIDGG 251


>UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase;
           n=23; Proteobacteria|Rep: 7-alpha-hydroxysteroid
           dehydrogenase - Burkholderia mallei (Pseudomonas mallei)
          Length = 256

 Score =  141 bits (341), Expect = 2e-32
 Identities = 75/226 (33%), Positives = 120/226 (53%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +AK LG+ GA VV+ SR+  +       + + G + E   CH+   E    L+     + 
Sbjct: 27  VAKLLGAFGAHVVVTSRRLDDCRAIADEIVAAGGSAEAAACHIGELEQIDALYASLEGRH 86

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +D+L            I+DTD   + K  DVN++  + ++      + K GGGSIV +
Sbjct: 87  GRLDVLVNNAATNPYYGPIVDTDLGAFQKTVDVNIRGYFFMSSRGAKLMGKNGGGSIVNV 146

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +S+    P    G Y ++K  ++ +TKA A E     +R N + PG+  TKFASA+T + 
Sbjct: 147 ASVNGVIPGYWQGIYSITKAAVISMTKAFAIECAASGVRCNALLPGLTDTKFASALTQTP 206

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              ++ L++VP++R  +P E+AGAV +LAS  +SY TG  + V GG
Sbjct: 207 EVLKQVLAHVPMRRAAQPTEMAGAVLYLASAASSYTTGTVLNVDGG 252


>UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;
           Azoarcus sp. EbN1|Rep: Short-chain alcohol dehydrogenase
           - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
           (strain EbN1))
          Length = 247

 Score =  139 bits (336), Expect = 8e-32
 Identities = 85/229 (37%), Positives = 119/229 (51%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKE-SNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           A A RL  EGA V     K   +  KA+++        +G V   ++      + +    
Sbjct: 20  ATALRLAKEGAHVACFDFKSLDSTMKAIEAAGGNASAFQGDVKRASDWAE---MVKQTVE 76

Query: 586 KFGGVDILXXXXXXXXXXXS-ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
           +FG VD+L             ILD  E+ WD+I D+NVK +WL  KE  P ++K GGG I
Sbjct: 77  RFGRVDVLANIAGVVSIGSDNILDQTEEGWDRIMDINVKGTWLGMKEVMPVMMKNGGGKI 136

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           V ++S+AA+     L AY  SK  ++ LT+  A E   +NI+VN V+PGI+ T      T
Sbjct: 137 VNVASLAAHVGLTNLAAYSASKGAVVALTRYAAMEYAKDNIQVNAVSPGIIQTPILGDTT 196

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                 +   ++ P  R GRPEEIA  V FLASD+A +ITG T +V GG
Sbjct: 197 PEM--TKLFSADTPAGRLGRPEEIANMVLFLASDEADFITGITHIVDGG 243


>UniRef50_Q8R9W0 Cluster: Dehydrogenases with different
           specificities; n=4; Bacteria|Rep: Dehydrogenases with
           different specificities - Thermoanaerobacter
           tengcongensis
          Length = 247

 Score =  138 bits (335), Expect = 1e-31
 Identities = 75/228 (32%), Positives = 120/228 (52%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKES-NVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           AIA RL  +G ++ I   K+  +  + V+ ++  G+    + C V+ +    +  E    
Sbjct: 20  AIAVRLAKDGFNIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDVSKYHEVEKAVEKVIE 79

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           +FG +D++            IL  +E+ WD++ DVN+K ++ + K A   ++K+  G I+
Sbjct: 80  EFGSIDVVVNNAGITKDNL-ILKMEEEEWDQVIDVNLKGAFNVIKFASKYMIKKRKGKII 138

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ISS+           Y  SK  ++GLTK++A E     I VN VAPG + T   + +  
Sbjct: 139 NISSVVGLMGNVGQANYAASKAGIIGLTKSVAKELASRGITVNAVAPGFIETDMTNVL-- 196

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            E   E  L ++PLKR G+PEE+A  VAFLAS  + YITG+ + V GG
Sbjct: 197 KEDIKEAMLKSIPLKRAGKPEEVAEVVAFLASSASDYITGQVINVDGG 244


>UniRef50_Q931B7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putative
           - Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 261

 Score =  138 bits (334), Expect = 1e-31
 Identities = 86/242 (35%), Positives = 129/242 (53%), Gaps = 7/242 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A R  + G  V I +  +++V +AV S+   G    G V  V +        + A S+
Sbjct: 21  ACAHRFAAGGGKVTIVANDKASVDEAVTSI---GDNAAGFVGDVRSKADMNAAVQAAVSR 77

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GGVDIL            ++DT ++VWD + D+N+K  +L +K A PE+ KRGGG+IV 
Sbjct: 78  HGGVDILACCAGIQRYGT-VVDTADEVWDDVLDINLKGIFLASKFAIPEMRKRGGGAIVA 136

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT---KFASAI 233
           ISS+ AY     + AY  SK  +  L +A+A +   +NI VN V P  + T   ++A+ +
Sbjct: 137 ISSVQAYASQTGVAAYTASKGAINALVRAMALDHAGDNITVNAVCPASIDTPMLRWAADL 196

Query: 232 TNSEAGAEKSL----SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL* 65
              E   E +L       PL R G+P E+A  VAFLAS+ A +ITG  + + GG  ++L 
Sbjct: 197 WKGEGTVEATLETWGKGHPLGRVGKPSEVAELVAFLASEKARFITGADIKIDGGVLSKLG 256

Query: 64  VV 59
           +V
Sbjct: 257 IV 258


>UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Burkholderiales|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 249

 Score =  136 bits (329), Expect = 6e-31
 Identities = 79/229 (34%), Positives = 123/229 (53%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+RL  EGASVVI            ++L+ EG+    +V  +      +RL +   + 
Sbjct: 22  ATARRLAQEGASVVITDINAELAQATAKALQDEGLAAHCIVGDITQEADVQRLVDETVAH 81

Query: 583 FGGVDILXXXXXXXXXXXSI-LDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           FGGV IL            + +  D+  WD + +V +K ++L A+   P  +++G G ++
Sbjct: 82  FGGVHILVNNAGAPRDKYLVKMSADD--WDFVMNVMLKGAFLAARAVMPHFIEQGWGRLI 139

Query: 406 FISSIAAY-QPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
            ISS A    PT+    Y  +K  L+G+ KA++ E     I  NCVAPG + T+   A+ 
Sbjct: 140 NISSRAHLGNPTQ--ANYSAAKAGLIGMAKALSMEEGRYGITANCVAPGFMETEMVQALP 197

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             E   E++++  P+KR GRP++IA AVAFLAS+ A +I+GE + V GG
Sbjct: 198 TYETIKERAVAAQPIKRVGRPDDIADAVAFLASERAGFISGEVLHVTGG 246


>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 277

 Score =  136 bits (329), Expect = 6e-31
 Identities = 78/232 (33%), Positives = 119/232 (51%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIAKR   EGA+VV+    E    +    L   G    G  C V + E    L +   ++
Sbjct: 23  AIAKRYLEEGATVVLADLSEEKTTERAAEL---GAGAHGRRCDVGDWEAFSTLIDATVAE 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL            +     Q WD +  VNV S +   + A P + ++GGG+I+ 
Sbjct: 80  FGRLDILVNNAGINRAGL-VPGFSLQHWDDLLRVNVSSVFYGCRAAIPHMRRQGGGAIIN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++SIA  +      AY  SK  ++  T+++A +   ENIRVN + PG V T+  + + + 
Sbjct: 139 VASIAGLRGETLAAAYSASKAAVVNFTRSLALDHADENIRVNAICPGSVETEMNNLMMSR 198

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
                + +  +P  RFGRP+++A   AFLASDDAS+I G+ + V GG  AR+
Sbjct: 199 PDYIAQWIKTIPANRFGRPDDVAALAAFLASDDASFIVGQAIPVDGGTSARM 250


>UniRef50_A0HIJ6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Comamonas testosteroni
           KF-1
          Length = 258

 Score =  136 bits (329), Expect = 6e-31
 Identities = 77/227 (33%), Positives = 122/227 (53%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI + L ++GAS++ C R      +  + LR+       +   +A+      L + A + 
Sbjct: 25  AICRVLAAQGASILACDRDSDACQRMAEELRNGQGQALALPADLADIPGITTLVQKALAW 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G VDIL           S+ D  +  W ++ D+N+++S  L++   P +   GGGS++ 
Sbjct: 85  KGQVDILVCNAGIQGPAGSLSDIGDIDWQQVMDINLRASVELSRHLLPAMALAGGGSVIL 144

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SSIA  +  + +G YG+SK  L  L + +A E   + IRVN V+PG++ T  A  + N 
Sbjct: 145 MSSIAGIRGNKAIGLYGLSKAALAQLARNLAVEWGPQAIRVNAVSPGLIRTPLAQPLLNH 204

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               ++ LS  PL+R G P+EIAGAVA LAS   ++ITG  +VV GG
Sbjct: 205 AEFMQRRLSLTPLRRVGEPQEIAGAVAMLASAAGAFITGHNLVVDGG 251


>UniRef50_A1SNH6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Nocardioides sp. (strain
           BAA-499 / JS614)
          Length = 250

 Score =  135 bits (326), Expect = 1e-30
 Identities = 84/229 (36%), Positives = 127/229 (55%), Gaps = 3/229 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSL--RSEGITVEGVVCHVANHEHR-RRLFEVAT 590
           IA+RL  EGA V + +RK+  +  AV+SL      I V G     A+ E   RR  E   
Sbjct: 22  IAQRLVDEGAKVCVTARKQEALDAAVESLGGAEHAIAVAGKADDPAHREDAVRRTIET-- 79

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
             FG +D+L            ++D D     KI +VN   +    + A+   +   GG++
Sbjct: 80  --FGSLDLLVNNAGINPVLAHLVDIDLDAARKIVEVNALGALAWVQSAHRAWMAEHGGAV 137

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           V ISS++  +P   +  YG SK  ++ LT+++A E +  ++RVN VAP IV T+FA  + 
Sbjct: 138 VNISSVSGVRPAPGIAMYGASKAMMISLTESLAVE-LGPSVRVNAVAPAIVKTQFAGPLF 196

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             E   ++  ++ PL+R G PE+IAGAVAFL SDDAS++TG+T+ + GG
Sbjct: 197 --EGREDEVAASYPLQRLGVPEDIAGAVAFLLSDDASWVTGQTITLDGG 243


>UniRef50_Q9F5J1 Cluster: SimJ1; n=5; Actinomycetales|Rep: SimJ1 -
           Streptomyces antibioticus
          Length = 273

 Score =  134 bits (324), Expect = 2e-30
 Identities = 79/232 (34%), Positives = 122/232 (52%), Gaps = 5/232 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+RL +EGA+V +  R E++    V S+R+ G    G+ C V   +      +   ++
Sbjct: 42  ATAQRLAAEGATVAVVDRTEADTADTVASIRAAGGRALGIGCDVTVTDLVEAAVDRTVAE 101

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D+L             +  DE  WD + DV++  +    + A  ++V++G G IV 
Sbjct: 102 FGRLDVLVNNAGVTRDSLVFMMGDED-WDTVIDVHLNGAARTVRAARRQMVRQGSGRIVN 160

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF----ASA 236
           +SSIAA    +    Y  +K  + G T+ +A E     I VN +APG + T      A  
Sbjct: 161 LSSIAALG-NQGQANYATAKAAIQGYTRTLAVELGPHGITVNAIAPGFIATTMTDDTARR 219

Query: 235 ITNSEAGAEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           + +      K++ S VP++R GRPE+IAG VAFLA  DASY+TG+T+ V GG
Sbjct: 220 MGSDPVALRKAVASRVPMRRVGRPEDIAGLVAFLAGPDASYLTGQTIYVDGG 271


>UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candidatus
           Pelagibacter ubique|Rep: Short chain dehydrogenase -
           Candidatus Pelagibacter ubique HTCC1002
          Length = 258

 Score =  134 bits (323), Expect = 3e-30
 Identities = 81/233 (34%), Positives = 122/233 (52%), Gaps = 7/233 (3%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESN---VGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
           I  RL SEGA +VI      N   + K +Q    E I VE    +VA  +    + +VA 
Sbjct: 21  ICVRLASEGAKIVIAEMDIENGEKISKKIQGNNGEAIVVE---TNVAEEDSANNMADVAI 77

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
            KFG +DIL            ILD  +Q WD +  VN+   +L  K   P ++K G G I
Sbjct: 78  KKFGKIDILVNNAGIRHINN-ILDHTKQQWDDMISVNLTGPYLCCKSVIPHMIKNGKGKI 136

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFA 242
           +   SIA++       AY  +K+ +LGLT+A+A +   +NI VN + PG++ T    KFA
Sbjct: 137 INFGSIASFMGRPDRVAYVAAKSGILGLTRALAVDLTGKNINVNTICPGLISTPFNQKFA 196

Query: 241 SAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              T+ +A  ++++    + R+G P +I+GA  FL+SDDA +I G  + + GG
Sbjct: 197 EDPTHGKAWGKETI----VGRWGLPSDISGAAVFLSSDDADFINGSEIKIDGG 245


>UniRef50_O61709 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 253

 Score =  134 bits (323), Expect = 3e-30
 Identities = 77/238 (32%), Positives = 119/238 (50%), Gaps = 6/238 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+ +RL   G  V   +   ++VGK  +     G  V      VAN EHR+ L      K
Sbjct: 16  AVVRRLAFTGYKVAAAADCPNSVGKVAEDNIKVGGDVTAFSLDVANAEHRKELITKVAEK 75

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GG+D L            I++T  + +DK+F  N+ + + L++ A   L K   GSI++
Sbjct: 76  LGGLDTLIIVPPQNEVLGEIIETSGEDFDKLFANNLTTPFRLSQAAMSTLAKSQNGSIIY 135

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S   + P+  +G Y V+ +++L LTK++A     + +RVN V  G++      A+ + 
Sbjct: 136 LTSCFGFTPSIDMGLYSVASSSVLSLTKSVAQSAAKQGVRVNSVVSGMIEGDGTGAVWDH 195

Query: 223 EAGAEKSL------SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
            +G E         S +PL R GRP ++A  V FLAS  A YITGE  +V GG   RL
Sbjct: 196 ASGEEARQIKQHLESMIPLGRLGRPSDVASYVEFLASTKARYITGENCIVGGGVSYRL 253


>UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=4; Actinomycetales|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
           sp. (strain RHA1)
          Length = 260

 Score =  133 bits (321), Expect = 5e-30
 Identities = 81/227 (35%), Positives = 117/227 (51%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+AK + + G +VV+ SR + +   A   +   G T  G+  H  + E  RR  +V   +
Sbjct: 23  AVAKAIAAAGGNVVLTSRSQESADAAAAQV---GGTAIGIAAHAVDEEAARRCVDVTLER 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL            ++D D   + K FDVN+ +  L         +   GG++V 
Sbjct: 80  FGSLDILVNNAGTNPSFGPVIDQDHARFAKTFDVNLWAPVLWTGLVTKAWMGEHGGAVVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +SI        +G Y  SK  L+ +TK +A E +   +RVN VAPG+V TK A A+   
Sbjct: 140 TASIGGMAFEANIGLYNASKAALIHVTKQLALE-LSPKVRVNAVAPGVVRTKLAEALWKE 198

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              A  +  +  L R G PE+IA AVAFL SD AS+ITGET+V+ GG
Sbjct: 199 HEQAVSA--STALGRIGEPEDIASAVAFLVSDAASWITGETMVIDGG 243


>UniRef50_Q8LFZ4 Cluster: Short chain alcohol dehydrogenase-like;
           n=5; Magnoliophyta|Rep: Short chain alcohol
           dehydrogenase-like - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 264

 Score =  133 bits (321), Expect = 5e-30
 Identities = 77/228 (33%), Positives = 118/228 (51%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+ + L    A V  CSR +  +   +   ++ G+ V G VC  +  + R +L + A+S 
Sbjct: 26  AVVEELAKFCAKVHTCSRNQEELNACLNDWKANGLVVSGSVCDASVRDQREKLIQEASSA 85

Query: 583 FGG-VDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           F G ++IL           ++  + E+ + KI   N++S++ L++ A+P L   G GSIV
Sbjct: 86  FSGKLNILINNVGTNVRKPTVEYSSEE-YAKIMSTNLESAFHLSQIAHPLLKASGVGSIV 144

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           FISS+A          YG +K  L  LT+ +A E   +NIR NCVAP  + T     +  
Sbjct: 145 FISSVAGLVHLSSGSIYGATKGALNQLTRNLACEWASDNIRTNCVAPWYIKTSLVETLLE 204

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            +   E  +S  PL R G PEE++  VAFL    +SYITG+ + V GG
Sbjct: 205 KKEFVEAVVSRTPLGRVGEPEEVSSLVAFLCLPASSYITGQVISVDGG 252


>UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcohol
           dehydrogenase TsaC; n=5; Proteobacteria|Rep:
           Toluenesulfonate zinc-independent alcohol dehydrogenase
           TsaC - Comamonas testosteroni (Pseudomonas testosteroni)
          Length = 252

 Score =  132 bits (319), Expect = 9e-30
 Identities = 75/230 (32%), Positives = 119/230 (51%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+RL   GA+V++         +    L + G    G+ C V+     R + + A ++
Sbjct: 20  AIARRLSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMACDVSKEADYRAVVDAAIAQ 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GG+ I+             L   E  +D+++ VN+KS +  A+ A P   ++G G +V 
Sbjct: 80  LGGLHIVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKSVYWSAQCALPHFAQQGHGVMVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS---AI 233
           ++S    +P   L  Y  SK  ++ LTK +A E     +R+N V P I  T   +    +
Sbjct: 140 VASTTGVRPGPGLTWYSGSKAAMINLTKGLALEFARSGVRINAVNPMIGETPMMADFMGM 199

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            ++ A  E+ LS +PL RF RP+++A AVAFLASDDAS++TG  + V GG
Sbjct: 200 EDTPANRERFLSRIPLGRFTRPDDVASAVAFLASDDASFLTGVCLDVDGG 249


>UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Geobacter metallireducens GS-15|Rep: Short-chain
           dehydrogenase/reductase SDR - Geobacter metallireducens
           (strain GS-15 / ATCC 53774 / DSM 7210)
          Length = 266

 Score =  132 bits (318), Expect = 1e-29
 Identities = 87/233 (37%), Positives = 125/233 (53%), Gaps = 5/233 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIAKRL   GA+V+I       + +A   L S    V+ +V         + LF      
Sbjct: 32  AIAKRLAEAGATVLITDINREAIEEAEHRLSSMKCKVKSLVSDAGREADIKSLFSYVADS 91

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIV 407
           FGGVDIL            ILD   + W ++  +N++S++L ++EA   +V++G GG IV
Sbjct: 92  FGGVDILVNNAGIYPATK-ILDMSLEQWREVIRINLESAFLCSQEAGRIMVRQGTGGVIV 150

Query: 406 FISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTK-FASAI 233
            ISS+AA +P  P L  YG SK  ++ LT++ A E     IR   V PG ++T    S +
Sbjct: 151 NISSMAALKPCFPGLAHYGASKGGVVNLTRSTALELAPHKIRAVAVVPGGILTGGVRSNL 210

Query: 232 TNSEA--GAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
             SE     +   + +PL  FG+P++IA  V FLASD A+YITG T++V GGA
Sbjct: 211 KQSEEKDSLQSIGATIPLGGFGQPDDIARTVLFLASDSAAYITGTTILVDGGA 263


>UniRef50_Q0SD55 Cluster: Possible short chain oxidoreductase; n=7;
           Actinomycetales|Rep: Possible short chain oxidoreductase
           - Rhodococcus sp. (strain RHA1)
          Length = 252

 Score =  130 bits (315), Expect = 3e-29
 Identities = 81/227 (35%), Positives = 125/227 (55%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+RL ++GA VVI +RK+  + +AV  L    + +  V     + +H+      A   
Sbjct: 22  AIAERLVADGARVVITARKKEALDEAVTHLGGPDVAL-AVAGRADDADHQGDAVRQAVET 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D L           S++D D     KI +VN  ++    ++ +   +K  GG+IV 
Sbjct: 81  FGSIDFLVNNTGINPVYGSLVDLDLAAARKIVEVNCIAALSWVQQVHKAWMKEHGGAIVN 140

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS+++ +    +G YG SK  L  LT+ +A E +  +IR+N VAP +V T+FA+ +   
Sbjct: 141 VSSLSSIRTAPGIGFYGASKAMLNSLTELMAVE-LGPDIRINGVAPAVVKTRFATKLYEG 199

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              A  +    PLKR G PE+I   VAFL SDDA+++TG+TVVV GG
Sbjct: 200 REDAVTAA--YPLKRLGVPEDIGSVVAFLLSDDAAWVTGQTVVVDGG 244


>UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1;
           Roseovarius sp. HTCC2601|Rep: Putative uncharacterized
           protein - Roseovarius sp. HTCC2601
          Length = 258

 Score =  130 bits (315), Expect = 3e-29
 Identities = 74/228 (32%), Positives = 115/228 (50%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A     EGA+V +       + + V+++R+ G T EG    +++            + 
Sbjct: 27  AAASIFAREGAAVAVWDIVPERIAETVEAVRAAGGTAEGFTVDISDSASIAEAARATENS 86

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G V +L             L TDE +WD+I  V++K  WL++K   P ++  GGG+IV 
Sbjct: 87  LGPVRVLFNNAGILDDYADALTTDEALWDRIMGVDLKGMWLVSKALLPGMIDAGGGAIVN 146

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++SIAA+       AY  +K  ++G T+ +A E   + IRVN VAPG V T   S I N+
Sbjct: 147 VASIAAFIAGGGGIAYTTAKHGVVGFTRQLALEYAPKGIRVNAVAPGAVETGMTSEILNN 206

Query: 223 E-AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E      +L   P  R  +PEE+A    FLAS++AS++ G  ++  GG
Sbjct: 207 EDLPVVHALRQAPAGRHAQPEELANVALFLASEEASFVHGAVLLADGG 254


>UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Shewanella
           pealeana ATCC 700345
          Length = 262

 Score =  130 bits (313), Expect = 5e-29
 Identities = 75/232 (32%), Positives = 117/232 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A RL +EGA V+IC R +  +   V  ++  G     V+  V+N        E   S+
Sbjct: 28  ATAVRLAAEGAKVMICGRNQPPLDLVVAQIKQAGGVATAVIADVSNETELVAAIERCASE 87

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +DI+            I + D Q W + F  +V  ++   K A  +L+K  GGSI+ 
Sbjct: 88  YGSLDIMVNNAMAFTWGS-IEEMDTQAWHENFKTSVDGTFWGTKAAM-KLMKSNGGSIIN 145

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SSI     T  +  Y  +K  +   ++A A E    NIRVN V P +V T     + ++
Sbjct: 146 LSSICGELGTPWMSGYSAAKAAVTNFSRAAAAEGAASNIRVNTVIPAVVETPATEGMLSN 205

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
               + +   +P+ R G+P+E+A  +AFLASD+ASY+TG ++ V GG  A L
Sbjct: 206 ATARKNTERLIPMGRVGQPDELASVIAFLASDEASYVTGVSLPVDGGRAAVL 257


>UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Geobacter metallireducens (strain GS-15 / ATCC
           53774 / DSM 7210)
          Length = 255

 Score =  129 bits (312), Expect = 6e-29
 Identities = 71/228 (31%), Positives = 124/228 (54%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A  L   GA++V+ SR E+++ K    + S+G+    V   +   +  + + +   ++
Sbjct: 25  AMALGLAEAGANLVLASRNEASMAKVASEVTSKGVQCLTVKTDMLKADDIQAMVDKGIAQ 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL            +  T+E  WD + D N+K  +L ++    E++K   G ++ 
Sbjct: 85  FGTIDILVNNAGINLVKPFVNLTEED-WDSVVDTNLKGYFLCSQVVGREMIKNKNGCVIN 143

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA-ITN 227
            +S+   +    + +Y  SK  ++ LT+ +A E    NIRVNC+APG +VT+ A   I  
Sbjct: 144 NASVFGLRGFPNIASYIASKGGVVQLTRGLAVEWARHNIRVNCIAPGYIVTEMAKRDIET 203

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +    E++L  +P+KR G+P E+A  V FLAS+ +SY+TG+ V + GG
Sbjct: 204 NPKILEQNLLKIPMKRGGQPREVADVVVFLASEASSYMTGQIVSMDGG 251


>UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 251

 Score =  129 bits (312), Expect = 6e-29
 Identities = 81/234 (34%), Positives = 125/234 (53%), Gaps = 4/234 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA R  +EGA V +    E    K    +  EG  V+     VA  E    L  +AT +
Sbjct: 21  AIALRFAAEGARVALADVDEGAARKVAAEI-GEGCLVQRTDVTVA--EEVEGLVRLATER 77

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +GG++++           +   T E+ ++++  VN++ ++L  K A P +   GGG+++ 
Sbjct: 78  WGGLEVMVNNAGVGVAATAP-QTSEEDFERVLAVNLRGTFLGMKYAIPAIRDSGGGAVIN 136

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SSIAA    +   AY  +K  +L LT+A A + +HE +RVNC+APG V T + S IT  
Sbjct: 137 MSSIAALVGLKDRAAYSAAKGGILALTRAGAIDHIHEGVRVNCIAPGTVETPWISRITAG 196

Query: 223 EAGAEKSLSNV----PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            A  E++   +    P  RF RPEE+A   A+LASD+A+ + G  +VV GG  A
Sbjct: 197 YADPEEARRRMRERQPHGRFVRPEEVAAMAAYLASDEAASVVGACMVVDGGVTA 250


>UniRef50_P50162 Cluster: Tropinone reductase 1; n=77;
           Viridiplantae|Rep: Tropinone reductase 1 - Datura
           stramonium (Jimsonweed) (Common thornapple)
          Length = 273

 Score =  129 bits (312), Expect = 6e-29
 Identities = 71/234 (30%), Positives = 117/234 (50%), Gaps = 4/234 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI + L   GA V  CSR E  + + ++  R +G+ VEG VC + +   R +L +     
Sbjct: 36  AIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSRTERDKLMQTVAHV 95

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           F G   +              D  E+ ++ I   N ++++ L++ AYP L     G+++F
Sbjct: 96  FDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIF 155

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SSIA +     +  Y  SK  +  +TK++A E   +NIRVN VAPG+++T         
Sbjct: 156 LSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKK 215

Query: 223 EAGAEKSLSN----VPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
               ++ + N     P+ R G+P+E++  +AFL    ASYITG+ +   GG  A
Sbjct: 216 NPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYITGQIIWADGGFTA 269


>UniRef50_Q93H96 Cluster: Putative oxidoreductase; n=1; Streptomyces
           avermitilis|Rep: Putative oxidoreductase - Streptomyces
           avermitilis
          Length = 275

 Score =  129 bits (311), Expect = 9e-29
 Identities = 84/227 (37%), Positives = 119/227 (52%), Gaps = 1/227 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IA  L   GA+VVI SR E  + KA  +L  E     GV     + EH+R   E A  +F
Sbjct: 48  IATALVERGANVVITSRTEDELRKAAAALGEERAL--GVAGDARDPEHQRIAVETAVDRF 105

Query: 580 GGVDILXXXXXXXXXXXS-ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           G +D+L             ++D D   + +  ++N+ S+    + A+   +   GG+IV 
Sbjct: 106 GSLDLLVNNVGGTERTARRLVDVDLASYRRTVEINLMSALTWVQTAWHGWLGEHGGAIVN 165

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISSIA         AYG +K  L   T+ +ANE     +RVN VA G V+T F  A  N 
Sbjct: 166 ISSIAGELAVPDGTAYGTAKAALNHFTRQMANELAPA-VRVNGVASGTVLTDFTRA--NV 222

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E   +K + ++PL+R G P ++  AVAFL SD+AS+ITG T+VV GG
Sbjct: 223 EGREDKVIGSIPLRRLGEPADVGAAVAFLLSDEASWITGHTLVVDGG 269


>UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Carboxydothermus
           hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Carboxydothermus
           hydrogenoformans (strain Z-2901 / DSM 6008)
          Length = 249

 Score =  129 bits (311), Expect = 9e-29
 Identities = 75/227 (33%), Positives = 115/227 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AKR+  EGA VVI +R +    KA   LR +G+ V  + C V      ++L      +
Sbjct: 21  ATAKRIAEEGAKVVIANRNKEEGEKAALQLREKGLEVYSIPCDVGKVADIKKLVSEVYGR 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +DIL            I +  E+ W+ + D+N+K ++    EA   ++ +  G IV 
Sbjct: 81  YGRIDILVNCAGVNVRKP-IEEYTEEDWNYMVDINLKGTFFACIEAGKHMIAQKEGVIVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++SI A +     G Y  +K  +  LTKA+A E    NIRVN V+P  + T+    +   
Sbjct: 140 LASIQAEEVLPERGIYATTKGGVKQLTKALAVEWAKYNIRVNAVSPAFIKTEMVEKVLQD 199

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                  ++  P++R G PEE+A A+ FL S  ASYITG  ++V GG
Sbjct: 200 PYWGNLIINKTPMRRPGTPEEVAEAILFLVSPKASYITGINLLVDGG 246


>UniRef50_Q1GNJ7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=23; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 258

 Score =  129 bits (311), Expect = 9e-29
 Identities = 76/232 (32%), Positives = 122/232 (52%), Gaps = 4/232 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS---EGITVEGVVCHVANHEHRRRLFEVA 593
           A A+ +  +GA VVI SRK+         + +   EG  +  V  ++++ +  + L    
Sbjct: 23  ATAEAMAEQGAKVVISSRKQDACDATAAEINARFGEGTAI-AVAANISSKDDLQNLVNET 81

Query: 592 TSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS-WLLAKEAYPELVKRGGG 416
            + FG +  L             L   ++ + KI D N+ S+ WL++  A PE+++RG G
Sbjct: 82  RAAFGKITALVCNAASNPYYGPGLGISDEQFRKIMDNNILSNHWLISMVA-PEMLERGDG 140

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           SI  ISSI   + +  +GAYG+SK   + + +  + E     +RVNC+APG++ T  A A
Sbjct: 141 SITIISSIGGLKGSPIIGAYGISKAADMQVARNFSVEFGPRGVRVNCIAPGLIRTDMARA 200

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           +  +    ++S +   LKR G P EIAGA  FLAS   ++ TG+T+V  GGA
Sbjct: 201 LWENPENLKRSTAASTLKRIGEPHEIAGAAVFLASKAGAFTTGQTIVCDGGA 252


>UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Kineococcus radiotolerans SRS30216|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Kineococcus radiotolerans SRS30216
          Length = 247

 Score =  129 bits (311), Expect = 9e-29
 Identities = 84/230 (36%), Positives = 127/230 (55%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A  L + GA V++  R ++    AVQSL + G T E +   ++     R L + A   
Sbjct: 22  AVAAVLAARGAHVLVSGRDDTRGRDAVQSLVNAGGTAEYLPADLSAASGVRELADAALDL 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G VDIL           +  +++  + D+++ +NVK+ +LL +   P++V++G G+IV 
Sbjct: 82  AGTVDILVNNAGVFSFGSTAGNSEIDI-DRMYAINVKAPYLLVQALAPKMVEQGSGTIVN 140

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           + + AA++ +   G YG SK  LL LT A A E     +RVN V+PG + T+     T +
Sbjct: 141 VLTGAAHRGSVTAGLYGSSKAALLLLTTAWAAEFGPSGVRVNAVSPGPIRTEG----TAN 196

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            AG +     +P +R G P E+A AVAFLASDDASYI G  + V GGA A
Sbjct: 197 GAGLDAVARALPARRLGEPVEVAAAVAFLASDDASYIHGAILPVDGGAIA 246


>UniRef50_A0VRR7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL
           12
          Length = 303

 Score =  129 bits (311), Expect = 9e-29
 Identities = 74/226 (32%), Positives = 118/226 (52%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A  LG  GA V++ +R+   +    ++LR+EGI  +     V +          A +  
Sbjct: 79  LALTLGQAGAEVILAARRADRLEAVAETLRAEGIVAQTAALDVTDAAS----VAAAVTTV 134

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +DIL            ++DT E  WD++ D N+K +W +++   P L+ R G +I+ +
Sbjct: 135 GPLDILINNSGVSGQDM-VIDTTEADWDRVLDTNLKGAWRVSRAFAPGLIARQG-TILNV 192

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +SI      + +G Y  SK  L+ LT+A+A E   + +RVN +APG + T   +    SE
Sbjct: 193 ASILGIGVLKTVGPYAASKAGLIQLTRAMALELARDGVRVNALAPGYIETPINTEFFASE 252

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           AG +K L  VP +R G+P ++  AV  L    A ++TG TVVV GG
Sbjct: 253 AG-QKMLRGVPQRRLGQPGDLDAAVLMLLGPGAGFVTGATVVVDGG 297


>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Chloroflexus|Rep: Short-chain
           dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
           9485
          Length = 256

 Score =  129 bits (311), Expect = 9e-29
 Identities = 78/238 (32%), Positives = 122/238 (51%), Gaps = 6/238 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A  L  EGA+VVI  R  +     V+ + + G     V+  V++     R+      +
Sbjct: 20  ATALALAREGAAVVIADRDAAATTALVEGINAWGGRALAVIADVSDESDAARIANDTVLE 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+D+L            I  T  Q+W +I +VN+   +L+++   PEL +RGGG+IV 
Sbjct: 80  FGGIDLLVNNAGIQQPGT-IESTTLQLWQEIINVNLTGVFLVSRFVMPELRRRGGGAIVN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA---SAI 233
           ++S+   +      AY  SK  ++ LT+A+A +   + IRVNCV PG++ T      +A+
Sbjct: 139 VASVYGLRAEAGWAAYAASKGGVIALTRAMALDGAPDGIRVNCVCPGLIDTSLLRANAAL 198

Query: 232 TNSEAGAEKSLS---NVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
            N++   E+  +    VPL R G PEE+A  +  L S  A Y+TG  +   GG  ARL
Sbjct: 199 VNTQRPDEELRAFARRVPLGRLGTPEEVAAVILCLLSPTAGYLTGAVITADGGWEARL 256


>UniRef50_Q47QE8 Cluster: Probable short-chain type
           dehydrogenase/reductase; n=1; Thermobifida fusca YX|Rep:
           Probable short-chain type dehydrogenase/reductase -
           Thermobifida fusca (strain YX)
          Length = 277

 Score =  128 bits (309), Expect = 1e-28
 Identities = 82/240 (34%), Positives = 122/240 (50%), Gaps = 9/240 (3%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI+ RL SEGA+V +    E +  K  + + ++G     V     N++  R LF+   S 
Sbjct: 42  AISHRLASEGATVYVADLSEESAKKVAEEITAQGGKAVPVQVDATNNDSLRALFDRIRSD 101

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG-GSIV 407
            G + +L             ++T ++ W K  DVN+KS++      Y  L    G GSI 
Sbjct: 102 HGVLHVLHAQVGMPGPGG--IETSDEEWQKNIDVNIKSAYYTCTLGYDLLKSANGKGSIT 159

Query: 406 FISSIAAY--QPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
             SS +A    P  P+  Y ++K +L+   +A+A +   + IRVN + PG V T   +  
Sbjct: 160 MTSSTSALVGSPFSPI--YSLTKGSLVPFARALALKGAPDGIRVNVICPGTVQTPMLAQF 217

Query: 232 TNSEAGAEKS------LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
              E GA+ S      + N+PL R  +PEEIA  +AFLASDDASY+TG T+ V GG  A+
Sbjct: 218 FGREPGADVSELTKDFIKNIPLGRGAQPEEIASVIAFLASDDASYVTGVTIPVDGGLTAK 277


>UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 252

 Score =  128 bits (309), Expect = 1e-28
 Identities = 80/229 (34%), Positives = 121/229 (52%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A     EGA V+I    E    + V+++R+ G       C V+  E    L   A  +
Sbjct: 21  ATALLFAREGACVLIGDINEEGASETVEAVRAAGGDAAFRRCDVSGEEEIAALVAAAGEE 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D++            + D   + ++    +N+ +++LL K A P + +  GGSI+F
Sbjct: 81  YGRLDVVFGNAGLLRTRP-LEDLSTKEFELHLRINLTANFLLTKYAAPVMRRHEGGSIIF 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI-TN 227
           ++S    + T    AY  SK  L+ +T+++A+E    NIRVNCV PG V T F      +
Sbjct: 140 MASAGGLRGTRGSVAYNASKGGLVNMTRSLADELAPHNIRVNCVCPGWVDTPFNRPFWEH 199

Query: 226 SEAGAEKS-LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           + AGAE+  L  VPL+R   PEE+A AV FLA + ASYITGE +V+ GG
Sbjct: 200 AGAGAEEEVLRGVPLRRQCTPEEVAPAVVFLAGEGASYITGEALVIDGG 248


>UniRef50_Q2U8E2 Cluster: Dehydrogenases with different
           specificities; n=4; Aspergillus|Rep: Dehydrogenases with
           different specificities - Aspergillus oryzae
          Length = 273

 Score =  128 bits (308), Expect = 2e-28
 Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 7/234 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ L   GA +  C  +  +     + L +EG   E    +V + E  +R+ EV  +K
Sbjct: 35  ATARVLSRNGAKIFGCDLQLESALHTKKRLEAEGGVCEVTTANVTSSEDVKRMVEVCVAK 94

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL              +  E+VWD   D+N+KS +L   E  P + K+GGG+IV 
Sbjct: 95  FGRIDILINNVGRSEPGGPA-EMTEKVWDAQTDINLKSVYLSCHEVLPIMEKQGGGAIVN 153

Query: 403 ISSIAAYQPT-EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           ++SIA  +   +P  AY  +K+ ++  TKA A    + NIR+N V PG++ T   S + +
Sbjct: 154 VASIAGIRYIGKPQVAYSAAKSAVIQFTKATAVIYANRNIRLNVVVPGLMHTPLVSYLAD 213

Query: 226 SEAGAE------KSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             AG +      K    VP+ R G   ++A   AFL SD A YITG+ +VV GG
Sbjct: 214 KYAGGDLEGFIAKRNKAVPMGRMGDSFDVANCAAFLLSDSARYITGQKIVVDGG 267


>UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=8;
           Actinomycetales|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Mycobacterium
           tuberculosis
          Length = 260

 Score =  127 bits (307), Expect = 3e-28
 Identities = 74/227 (32%), Positives = 118/227 (51%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA++L + GA VV+ +R++    +A   +    +   GV  H  + +  RR  ++   +
Sbjct: 23  AIAQQLAAAGAHVVLTARRQEAADEAAAQVGDRAL---GVGAHAVDEDAARRCVDLTLER 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG VDIL            +L+ D   + KIFDVN+ +  +         +   GG++V 
Sbjct: 80  FGSVDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHGGAVVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +SI     +  +G Y  +K  L+ +TK +A E +   IRVN + PG+V T+ A A+   
Sbjct: 140 TASIGGMHQSPAMGMYNATKAALIHVTKQLALE-LSPRIRVNAICPGVVRTRLAEALWKD 198

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               +   + + L R G P +IA AVAFL SD AS+ITGET+++ GG
Sbjct: 199 HE--DPLAATIALGRIGEPADIASAVAFLVSDAASWITGETMIIDGG 243


>UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular
           organisms|Rep: Alcohol dehydrogenase - Bordetella
           parapertussis
          Length = 252

 Score =  126 bits (305), Expect = 5e-28
 Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 3/229 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IA     EGA VV+    E+   +   ++ + G     V   V+++     L       F
Sbjct: 21  IAATFAREGAKVVVADINEAGGQRVAAAINAAGGQAVFVRADVSDNAAVANLLAATLKAF 80

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           GG+DI+            +L+ +E  +D+I+ +NVKS +L A+   P     GGGS + I
Sbjct: 81  GGLDIVVNNAGTTHRNRPMLEVEEDEFDRIYAINVKSIYLTARHMVPHFRAHGGGSFINI 140

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS---AIT 230
           +S AA +P   L  Y  SK  ++  +K++A E   +NIRVNCV P I  T   +    + 
Sbjct: 141 ASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNCVNPVIGATGLLADFMGVP 200

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           ++    ++ L+ +PL RF  P++IA A  +LASD+A++ITG  + V GG
Sbjct: 201 DTPENRKRFLATIPLGRFSTPQDIANACLYLASDEAAFITGACLEVDGG 249


>UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=4; Halobacteriaceae|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 269

 Score =  126 bits (305), Expect = 5e-28
 Identities = 73/228 (32%), Positives = 108/228 (47%), Gaps = 2/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVV--CHVANHEHRRRLFEVAT 590
           AIA+   ++GA VV+CSR++ NVG     +       E V   C V + E    L E   
Sbjct: 35  AIAEEFAADGADVVVCSREQDNVGPVADEINDSDRPGEAVAIECDVTDREAVEALVEATV 94

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
            +FGG+D+L              D  E  W  I D+N+  ++   + A   L   GGG++
Sbjct: 95  DEFGGLDVLVNNAGASFMSGFD-DISENGWKTIVDINLHGTYHCTQAAGDALAADGGGTV 153

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           + +SS+A  Q    +  YG +K  +  LT  ++ E    +IR+NC+APG V T      +
Sbjct: 154 INLSSVAGEQGAPYMSHYGAAKAGVSNLTSTLSAEWADRDIRINCIAPGFVAT--PGVES 211

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
                A+        +R G  EEIA    FLAS  +SYI G+T+  AG
Sbjct: 212 QMGVSADNIDREAVERRIGLSEEIADIALFLASPASSYIVGQTITAAG 259


>UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=123; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia
           conorii
          Length = 241

 Score =  126 bits (305), Expect = 5e-28
 Identities = 79/227 (34%), Positives = 124/227 (54%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+ L   G+ V+I    E  + +++  +  +  T+E  VC++A+ E  R L     SK
Sbjct: 21  AIARLLHKLGSHVIISGSNEEKL-QSLGKVVKDNYTIE--VCNLADKEECRNLI----SK 73

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
              +DIL           +I   DE  +DK+ D+N+K++++L +EA  ++++   G I+ 
Sbjct: 74  ASKLDILVCNAGITSDTLAIRMKDED-FDKVIDINLKANFILNREAIKKMIQNRYGRIIN 132

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISSI           Y  SK  L+G+TK+++ E     I VN VAPG + +     +  +
Sbjct: 133 ISSIVGISGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNTVAPGFIKSDMTDKL--N 190

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E   E  +  +PL  +G PE++A AVAFLASD ASYITG+T+ V GG
Sbjct: 191 EKQREAIVQKIPLGTYGMPEDVAHAVAFLASDQASYITGQTIHVNGG 237


>UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep:
           Oxidoreductase - Geobacillus kaustophilus
          Length = 260

 Score =  126 bits (304), Expect = 6e-28
 Identities = 77/234 (32%), Positives = 121/234 (51%), Gaps = 5/234 (2%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IA  L   GA+VV+CSRK     +  + L   G+    + C V N E  + + E    +F
Sbjct: 27  IAVGLAEAGANVVVCSRKVEACEQVKEKLEQLGVRSLALRCDVTNPEEVKHVVETTVKEF 86

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELV-KRGGGSIVF 404
           GG+DIL            + +   + W K+ +VNV  ++L+++     ++ K+ GGSI+ 
Sbjct: 87  GGIDIL-VNNSGATWGAPVEEMPLEAWQKVINVNVTGTFLMSQAVGKVMIAKQTGGSIIN 145

Query: 403 ISSIAAYQPTEP----LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           I+S+A    T P       Y  SK  ++  T+ +A +     IRVN VAPG   TK +  
Sbjct: 146 IASVAGLGGTHPDILNTIGYNTSKGAVITFTRDLAAKWGKHGIRVNAVAPGFFPTKMSKV 205

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           +   E   +K L + PL RFG  +++ GAV FLAS  ++++TG  +VV GG+ A
Sbjct: 206 VL--ERVGKKVLEHTPLGRFGGEDDLKGAVLFLASPASAFVTGALLVVDGGSHA 257


>UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Candidatus Desulfococcus oleovorans
           Hxd3|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Candidatus Desulfococcus oleovorans Hxd3
          Length = 266

 Score =  126 bits (304), Expect = 6e-28
 Identities = 72/234 (30%), Positives = 117/234 (50%), Gaps = 7/234 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A      GA V I SRK  N+    + ++++G     V  HV   +    + E   ++
Sbjct: 26  ATALAFADAGADVAIVSRKMENLAPVAEEIKAKGKRCLPVAAHVGRMDQLPAIVEQVVAE 85

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIV 407
           FG +DIL           +I +  E++WD I  +N+K  + L++     + ++G GGSI+
Sbjct: 86  FGQIDILVNNAATSPAYATIFEAQEKLWDSIIGLNLKGLYFLSQAVARVMEEKGAGGSII 145

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            +SSI  + P   +G Y +SK  +   T+++A E     IRVN +APG   TK    +  
Sbjct: 146 NVSSIDGFAPQAQVGIYSISKAGVNMATRSMALELAPHKIRVNAIAPGATRTKLFEGLFA 205

Query: 226 --SEAGAEKSLSNV----PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              E   EK +  +    PL R   P+++ G + +LASD ++Y+TG+ V V GG
Sbjct: 206 FLPEDEREKQIQQIGQAFPLGRVAVPDDMVGLMLYLASDASAYMTGQVVAVEGG 259


>UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Bacillus halodurans
          Length = 246

 Score =  126 bits (303), Expect = 8e-28
 Identities = 75/228 (32%), Positives = 113/228 (49%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVI-CSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           A A  L   GA+VV+  +  +    K V  ++  G+    +   VA+ E  + + +    
Sbjct: 19  ATAMELARHGANVVVNYAGNKEKAEKVVAEIKELGVEAIAIQADVADSESVQAMVKETID 78

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
            FG VDIL             +   E+ WD + D N+K  +  +K     ++K+  G I+
Sbjct: 79  TFGAVDILVNNAGITRDNL-FMRMKEEDWDAVIDTNLKGVFHCSKAVTRPMMKQRFGRII 137

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            +SS+           Y  +K  ++GLTK +A E  + NI VN VAPG + T     +  
Sbjct: 138 NVSSVVGAIGNAGQANYVAAKAGVIGLTKTLARELANRNITVNAVAPGFIETDMTGEL-- 195

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            E    + L  +PL R G+PEE+A AV FLASDDASY+TG+T+ V GG
Sbjct: 196 PEDVKAQMLGQIPLARLGQPEEVAKAVRFLASDDASYLTGQTIHVNGG 243


>UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Ralstonia metallidurans CH34|Rep: Short-chain
           dehydrogenase/reductase SDR - Ralstonia metallidurans
           (strain CH34 / ATCC 43123 / DSM 2839)
          Length = 269

 Score =  126 bits (303), Expect = 8e-28
 Identities = 82/227 (36%), Positives = 120/227 (52%), Gaps = 9/227 (3%)
 Frame = -3

Query: 736 GASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXX 557
           GA V +  R  ++  +    +R+EG   E  V  VA      RLF  A   FG +D+L  
Sbjct: 39  GARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIARLFAEAREHFGPIDVLHH 98

Query: 556 XXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQP 377
                     +LDTD + +D   +VNV+S  L +++  P +V+RG G+IV +SS+A  + 
Sbjct: 99  NVGIGKTGG-VLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGLRY 157

Query: 376 T-EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV--------VTKFASAITNS 224
              P  +Y VSK  L+  T+ IA +     IR NCV PG++        V K  SA +  
Sbjct: 158 IGYPHLSYSVSKAALIQFTRMIAQQYAGSGIRANCVVPGLIDTPRIAHTVAKQFSADSLD 217

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +A A ++   VP++R G   ++A A AFLASD A+YITG  +VV GG
Sbjct: 218 DARAARA-RQVPMQRMGTAWDVAHACAFLASDAAAYITGTELVVDGG 263


>UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 -
           Clostridium kluyveri DSM 555
          Length = 250

 Score =  126 bits (303), Expect = 8e-28
 Identities = 72/231 (31%), Positives = 119/231 (51%), Gaps = 4/231 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVI----CSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEV 596
           AIA  +  EGA +++      +K   V K ++ ++   I V+     V+     +++ ++
Sbjct: 20  AIAIEMAKEGARIIVNYNNSKKKALEVVKEIEDIKGTSIAVKA---DVSKRNEVKKMIDI 76

Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
           A   FG + IL               TD++ WDK+F VN+K +++  +E  P ++K   G
Sbjct: 77  AVENFGEIHILVNNAGILQQKPFESITDDE-WDKMFQVNMKGAFICTQECIPYMLKNNFG 135

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
            I+ ISSI           Y  +K  ++ L +++A     + I  NC+APG+V+T+ ++ 
Sbjct: 136 RIINISSIGGQWGGNLAVHYSATKAGIISLARSLARIYSKDGINTNCIAPGLVLTEMSAK 195

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              +EAG EK L  +P+ R   PEEI     FLAS+D SYITG+T+   GG
Sbjct: 196 EMATEAGKEK-LKGIPINRPAAPEEIGRIAVFLASEDGSYITGQTLNANGG 245


>UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinobacter sp. ELB17
          Length = 264

 Score =  126 bits (303), Expect = 8e-28
 Identities = 83/238 (34%), Positives = 114/238 (47%), Gaps = 6/238 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A RL  EGA V++    E  + +   +L  EG      +  VA+    + L   A   
Sbjct: 21  ATALRLACEGAQVIMADTSELGLAET-GNLMPEGAEYLRRLVDVADEAQVKELVSDAMDA 79

Query: 583 FGGVDILXXXXXXXXXXXS---ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
           FG +DIL               +++ +   WDK+  VN+  + LL K   P +  R  GS
Sbjct: 80  FGKIDILCNIAGIASTGKGHPPVIENERDEWDKVLSVNLIGTMLLIKHVAPHMQARKLGS 139

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           IV  +SIA  +      AY  SK  ++ LT   A +    NIRVN V PG+V T    A+
Sbjct: 140 IVNTASIAGIRSGAGGNAYSASKAGVINLTMTAACDLGDHNIRVNAVCPGLVETGMTRAV 199

Query: 232 ---TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
                +   A K  +   L+R+G PEEIA A+ F ASDDASYITG+ + V GG  A L
Sbjct: 200 FDYARTHEKAHKLGARCELRRYGDPEEIAAAILFFASDDASYITGQALPVDGGNTASL 257


>UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Nocardioides sp. JS614|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Nocardioides sp.
           (strain BAA-499 / JS614)
          Length = 258

 Score =  126 bits (303), Expect = 8e-28
 Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 6/237 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ L SEGA+V +   +  +  + V ++   G     +  +VA+            ++
Sbjct: 23  AAAELLASEGAAVGVLDLRAESAEETVAAIVDSGGRAIALAANVADSAEVEAAIAKVVAE 82

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +GG+++L               TDE  W++ F VN K +++ ++ A P L   GGG+IV 
Sbjct: 83  YGGLNVLYNNAGCDSRGSVADATDED-WERAFSVNAKGTFVCSRAAVPHLTASGGGAIVN 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
             S+AA        AY  +K  ++ LT+++A +     IRVN + PG V T     +  +
Sbjct: 142 QGSVAALVGVPNFAAYCAAKGAVVALTRSMAIDLAPRKIRVNVICPGTVFTPLMEPMLRA 201

Query: 223 ------EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
                 EAG  K+L   P+ R G PEEIA   AFLASDD+S++TG  +   GG  A+
Sbjct: 202 RGDGDLEAGLAKTLVKYPIGRLGTPEEIARVAAFLASDDSSFLTGSVIAADGGMTAQ 258


>UniRef50_P55541 Cluster: Uncharacterized short-chain type
           dehydrogenase/reductase y4lA; n=5; Rhizobiales|Rep:
           Uncharacterized short-chain type dehydrogenase/reductase
           y4lA - Rhizobium sp. (strain NGR234)
          Length = 278

 Score =  126 bits (303), Expect = 8e-28
 Identities = 77/236 (32%), Positives = 118/236 (50%), Gaps = 4/236 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A  +  EG  VV+     S        + +E      +   +A+ +    LFE A   
Sbjct: 21  ACALAIAREGGRVVVADLDGSAAIACTAQIAAEAGNALAMAMDIADAQAVAALFETAERH 80

Query: 583 FGGVDILXXXXXXXXXX---XSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
           FGGVD+L              +ILD D  VWD+    N++ + L  ++A P ++ RGGG+
Sbjct: 81  FGGVDLLVNNASAMHLTPRDRAILDLDLAVWDQTMATNLRGTLLCCRQAIPRMIARGGGA 140

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           IV +SS           +Y VSK  +  L+ ++A +  H  IR N VAPG+++T+    +
Sbjct: 141 IVNMSSCQGLSGDTAQTSYAVSKAAMNMLSASLATQYGHAQIRCNAVAPGLIMTE--RLL 198

Query: 232 TNSEAGAEKSLS-NVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
              +   ++ LS +  L R G PE++A  VAFL SDDAS+ITG+ V + GG  A +
Sbjct: 199 AKLDKCMQRHLSRHQLLPRVGHPEDVAALVAFLLSDDASFITGQVVCIDGGMLAHM 254


>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=225; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
           cholerae
          Length = 244

 Score =  126 bits (303), Expect = 8e-28
 Identities = 76/227 (33%), Positives = 113/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+ L   GA V+  +  ES        L   G   +G+  +V N E    + +  T +
Sbjct: 20  AIAELLAERGAKVIGTATSESGAQAISDYLGDNG---KGMALNVTNPESIEAVLKAITDE 76

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGGVDIL            ++   E+ W  I + N+ S + L+K     ++K+  G I+ 
Sbjct: 77  FGGVDILVNNAGITRDNL-LMRMKEEEWSDIMETNLTSIFRLSKAVLRGMMKKRQGRIIN 135

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           + S+           Y  +K  ++G TK++A E     + VN VAPG + T    A+ + 
Sbjct: 136 VGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAPGFIETDMTKALNDE 195

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +  A  +L+ VP  R G P EIA AVAFLAS +A+YITGET+ V GG
Sbjct: 196 QRTA--TLAQVPAGRLGDPREIASAVAFLASPEAAYITGETLHVNGG 240


>UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Thermotoga|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Thermotoga maritima
          Length = 255

 Score =  125 bits (302), Expect = 1e-27
 Identities = 75/229 (32%), Positives = 116/229 (50%), Gaps = 3/229 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSK 584
           IA+ L   G SVV+ SR      +A Q L  + G+      C V+N+E  ++L E    K
Sbjct: 25  IAQGLAEAGCSVVVASRNLEEASEAAQKLTEKYGVETMAFRCDVSNYEEVKKLLEAVKEK 84

Query: 583 FGGVD-ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           FG +D ++                DE  + ++ +VN+  ++ + +EA+  L +    SI+
Sbjct: 85  FGKLDTVVNAAGINRRHPAEEFPLDE--FRQVIEVNLFGTYYVCREAFSLLRESDNPSII 142

Query: 406 FISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
            I S+   + T P + AY  SK  +  LTKA+A E     IRVN +APG   TK   A+ 
Sbjct: 143 NIGSLTVEEVTMPNISAYAASKGGVASLTKALAKEWGRYGIRVNVIAPGWYRTKMTEAVF 202

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +     +  L  +PL R G PE++ G   FLAS++A Y+TG+ + V GG
Sbjct: 203 SDPEKLDYMLKRIPLGRTGVPEDLKGVAVFLASEEAKYVTGQIIFVDGG 251


>UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=11; Bacteria|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Xylella fastidiosa
          Length = 255

 Score =  125 bits (302), Expect = 1e-27
 Identities = 72/228 (31%), Positives = 113/228 (49%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+     GASVV+  R      +   ++ +EG T  G+ C V++      L E   ++
Sbjct: 24  ATARGFAQGGASVVLADRDGERAAQEAAAIVAEGGTAIGLACDVSDEAQVAALVEKTVAE 83

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D                +   + +D++  +N++  WL  K    ++ ++G G IV 
Sbjct: 84  YGRLDFAFNNAGVMAKIAPFAEATSEEFDRVIGINLRGVWLCMKYELQQMQRQGSGVIVN 143

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAITN 227
            +S+ A      +GAY  SK  +LGLT+A A E   + IRVN V PG + T+ A   +  
Sbjct: 144 NASVGALTGNVGIGAYIASKHGVLGLTRAAALEYCKKGIRVNAVNPGTIDTQIARDVVGG 203

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           S+    K  ++ P+ R GRPEEIA AV +L S   SY+ GE + V GG
Sbjct: 204 SDEAFAKLGASAPIGRAGRPEEIASAVLWLCSPGGSYVIGEGLTVDGG 251


>UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep:
           Alr4456 protein - Anabaena sp. (strain PCC 7120)
          Length = 267

 Score =  125 bits (302), Expect = 1e-27
 Identities = 76/227 (33%), Positives = 115/227 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+   + GA VVI +R    + + +++  S G  V GV   V+  E R+ + +  +  
Sbjct: 37  AIAQEFLALGAEVVIVARNAEAIEQQMKAWHSAG-KVHGVAADVSTSEGRQMMLDYVSKT 95

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL           +  D  E+ +  IF +N+ S + L++  YP L      SIV 
Sbjct: 96  FGELDILVNNVGTNIRKKAT-DYTEEEFAAIFQINLTSIFELSRLFYPLLKTSKNSSIVN 154

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I S+A          YG++K  L+ LT+++A E   + IRVN +AP  + T     + N+
Sbjct: 155 IGSVAGLISVRTGAPYGMTKAALVQLTRSLAVEWADDGIRVNAIAPWFIQTPLTEPLLNN 214

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                  LS  P+KR G+PEE+A   AFL    ASYITG+ + V GG
Sbjct: 215 PETLSAVLSRTPMKRVGQPEEVASLTAFLCMPTASYITGQCIAVDGG 261


>UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Acidobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 257

 Score =  125 bits (302), Expect = 1e-27
 Identities = 70/227 (30%), Positives = 113/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI+  L   GA VV  +R+E  V  A   +   G     V   V +    + L     +K
Sbjct: 24  AISFGLADAGADVVSTARREEQVNAAADEIERRGRQTLRVCSDVTSRASIQSLCNAVLAK 83

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           F  VDIL           + L   E  W+KI D N+  +    +     +++RG G I+ 
Sbjct: 84  FQKVDILVNCAGTTKRTPT-LTVSEDEWNKILDTNLTGALRACQVFGKHMIERGYGRIIN 142

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I+S++++     + AY  SK  LL LT+++A E   + + VN +APG+  T   + + ++
Sbjct: 143 IASLSSFVALHEVAAYSASKAALLSLTRSLAVEWSKKGVTVNAIAPGVFRTALNTELLDN 202

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               ++ L   P++RFG  EE+ GA  +LASD AS++TG+ + V GG
Sbjct: 203 TPRGQEFLMRTPMQRFGNTEELVGAAVYLASDAASFVTGQAITVDGG 249


>UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent
           epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1
          Length = 263

 Score =  125 bits (302), Expect = 1e-27
 Identities = 75/232 (32%), Positives = 121/232 (52%), Gaps = 2/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A  L +EGA VV C+R+E    + +  ++++G     V   V +      + + A + 
Sbjct: 21  ATALTLAAEGAKVVACARREDKGRELIALIQAQGGQATWVTADVLSERDVEAMVQAALTT 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D              I  T+++ +D +   NV+S++   K     ++  GGG+IV 
Sbjct: 81  YGRLDGAFNNAGTSLSKPFIEMTNDE-YDTVMATNVRSAFWCMKYQLKAMLAGGGGAIVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA--IT 230
            +S++A +    L AY  SK  L  LT+ +A E   +NIR N V+PGIV ++ A+A    
Sbjct: 140 CASVSAVRAMPGLSAYSASKAGLAALTRGVAVEYAQKNIRANTVSPGIVESEMATAGWRL 199

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           +   G   + S  P+ R G P+E+AG VAFL SD AS++TG+ + V GG  A
Sbjct: 200 HDRMGRAFASSFQPMNRVGTPQEVAGLVAFLLSDKASFLTGQDLAVDGGLTA 251


>UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3;
           Proteobacteria|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Erythrobacter
           sp. NAP1
          Length = 267

 Score =  125 bits (302), Expect = 1e-27
 Identities = 80/233 (34%), Positives = 117/233 (50%), Gaps = 4/233 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEG-ITVEGVVCHVANHEHRRRLFEVATSK 584
           IA+R  +EGA+VVI +R      K   +L ++  +T  G    V++ +    +      +
Sbjct: 25  IARRFHAEGANVVINARNAEKCAKVADTLDADRTLTCPG---DVSSSDFANEIVAKTVER 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKR---GGGS 413
           FGG+D L                DE++ D+I D+NVK    L + A P L K    GGGS
Sbjct: 82  FGGLDCLVNNAGVGGSSMLHKTDDEEI-DRIIDINVKGVIYLCRAAIPHLRKSEAVGGGS 140

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           I+ ISS++       L  Y  SK  +  LT+ +A +     IRVN + P I  +     I
Sbjct: 141 IINISSVSGIGGDSMLPIYNASKGAMTNLTRGLAQQIGGMGIRVNAINPSITRSDMVDGI 200

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
             ++A  E  +  VP+ R G PE+IA A AFLAS+DA++ITG  + V GG  A
Sbjct: 201 LANDALLEAFMRRVPMGRIGEPEDIAAACAFLASEDAAFITGVNLPVDGGVSA 253


>UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Burkholderia cenocepacia MC0-3|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Burkholderia cenocepacia MC0-3
          Length = 277

 Score =  125 bits (302), Expect = 1e-27
 Identities = 80/231 (34%), Positives = 113/231 (48%), Gaps = 4/231 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A RL  EGASVV+         + V+ +   G         + +      LF++    
Sbjct: 21  ACAARLAHEGASVVVADLNLEGAQEQVRHIADSGGHAVAARVDIGDECSIEALFDLTLKT 80

Query: 583 FGGVDIL----XXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
           +GG+DIL               +I   D  VWD    +N++ + L ++ A P +  RGGG
Sbjct: 81  WGGLDILHNNAAATSLSSTADAAIEAIDVAVWDDTMRINLRGTMLASRRALPLMRSRGGG 140

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           SI+  SS AA        AYGV K  +  LT+ IA +   E IR N +APG++VT    A
Sbjct: 141 SIINTSSGAAQAGALGYSAYGVCKAGIENLTRYIAAQYGKEGIRCNAIAPGLIVTPVTRA 200

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               E G E  LS+    R G PE+IA AV +LASD+A+++TG+   V GG
Sbjct: 201 YYAGELG-EMMLSHHLTPRLGVPEDIAHAVVYLASDEAAFVTGQVFNVDGG 250


>UniRef50_Q89P11 Cluster: Oxidoreductase; n=8; Proteobacteria|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 264

 Score =  125 bits (301), Expect = 1e-27
 Identities = 82/228 (35%), Positives = 119/228 (52%), Gaps = 2/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IA  L + GA+VV+  R E+    A + + + G   E + C V   +   R      +K 
Sbjct: 24  IALGLSAVGATVVVLDRDEAGAAVAAE-ISASGGRAEFLACDVTRDDSVARAAGEVAAKV 82

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQV-WDKIFDVNVKSSWLLAKEAYPE-LVKRGGGSIV 407
           G   IL             LDT     WD+I  +N+ + +L    A+ E ++ RG G+IV
Sbjct: 83  GEATILVNNAGTMLPGG--LDTTSMADWDRILSLNL-TGYLRCARAFGEPMLARGAGAIV 139

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ++SI+A  P    GAY VSK  +  L++ +A E     +R N V+PG++ T    AI  
Sbjct: 140 HVASISASFPQSYSGAYSVSKAGVAVLSRQLAVEWGPRGVRSNVVSPGMIRTPMTEAIYQ 199

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           ++   E   + VP +R GRPE+IA AV FLAS+ ASYITGE +VV GG
Sbjct: 200 TQGVYEARRALVPARRIGRPEDIADAVVFLASERASYITGEEIVVDGG 247


>UniRef50_Q1NA92 Cluster: Gluconate 5-dehydrogenase; n=1;
           Sphingomonas sp. SKA58|Rep: Gluconate 5-dehydrogenase -
           Sphingomonas sp. SKA58
          Length = 264

 Score =  125 bits (301), Expect = 1e-27
 Identities = 74/232 (31%), Positives = 118/232 (50%), Gaps = 5/232 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATS 587
           A+A  L   G +V + SR E++       +    G+   G+ C++A+             
Sbjct: 32  AMAATLADLGCAVALASRTEADCADLAAGIAERFGVPAVGLSCNIADEASVEAAVAGTID 91

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           + GG+DIL              D   + W K+ DVNV  ++L  + A   ++  GGG+IV
Sbjct: 92  RLGGLDILINNAGASWWGLP-QDIPLKGWQKVMDVNVTGTFLACRHAARHMIAAGGGAIV 150

Query: 406 FISSIAAYQPTEP----LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
            I+S+ A+   +P    +  Y  SK  ++ LT  +A +    NIRVN +APG + T    
Sbjct: 151 NIASVGAFLSYQPDAGQVVPYTTSKAAIVHLTSDLAAQWAGHNIRVNAIAPGSIETGMTE 210

Query: 238 AITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            +    A  EK+ + + ++RFGRP+E+AG +A LASD  S+ITG+T +V GG
Sbjct: 211 TL--DPAIQEKTRAGILMRRFGRPDEVAGTLALLASDAGSFITGQTFLVDGG 260


>UniRef50_Q3EBS2 Cluster: Uncharacterized protein At2g29340.1; n=5;
           core eudicotyledons|Rep: Uncharacterized protein
           At2g29340.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 307

 Score =  125 bits (301), Expect = 1e-27
 Identities = 74/228 (32%), Positives = 117/228 (51%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI + L   GA + +C   E+ + +++     +G  V G VC VA+   R  L +  +S+
Sbjct: 24  AIVEELAGFGARIHVCDISEAKLNQSLSEWEKKGFQVSGSVCDVASRPEREELMQTVSSQ 83

Query: 583 FGG-VDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           F G ++IL           +   T++     I   NV++++  ++ ++P L   G GSI+
Sbjct: 84  FDGKLNILVSNVGVIRSKPTTEYTEDDFAFHISS-NVEAAYHFSQLSHPLLKASGYGSII 142

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           F+SSIA     +    YG++K  L+ L K +A E   + IR N VAP ++ T  + +   
Sbjct: 143 FVSSIAGVISFDAGSIYGLTKGALIQLAKNLACEWAKDGIRANAVAPNVINTPLSQSYLE 202

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             +  +  LS  PL R G P E+A  VAFL    ASYITG+T+ V GG
Sbjct: 203 DVSFKKALLSRTPLGRVGEPNEVASLVAFLCLPAASYITGQTICVDGG 250



 Score = 38.7 bits (86), Expect = 0.16
 Identities = 24/60 (40%), Positives = 29/60 (48%)
 Frame = -3

Query: 277 CVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETV 98
           CV  G+ V  F      S    E  LS   L+R G P E++  V FL    ASYITG+ V
Sbjct: 246 CVDGGLTVNGF------SYQPEEALLSRTSLRRVGEPNEVSSLVVFLCLPAASYITGQMV 299


>UniRef50_Q08632 Cluster: Short-chain type dehydrogenase/reductase;
           n=9; Spermatophyta|Rep: Short-chain type
           dehydrogenase/reductase - Picea abies (Norway spruce)
           (Picea excelsa)
          Length = 271

 Score =  125 bits (301), Expect = 1e-27
 Identities = 81/234 (34%), Positives = 115/234 (49%), Gaps = 8/234 (3%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSL-----RSEGITVEGVVCH--VANHEHRRRLF 602
           IA  +  +GA VVI      +  + V S+      S G  V  +VC   VA      +LF
Sbjct: 37  IALNMAEKGAKVVIHYSSNQHAAEEVASIINNKSPSSGDGVRAIVCKADVAEPSQVAQLF 96

Query: 601 EVATSKFGGVDILXXXXXXXXXXXSIL-DTDEQVWDKIFDVNVKSSWLLAKEAYPELVKR 425
           + A   FG + I+             L  T ++ WD+IF VN K ++L ++EA   +V+ 
Sbjct: 97  DTAEHAFGPLHIVVNNAGVTDSKYPTLAQTSDEEWDRIFQVNCKGAFLCSREAAKRVVRG 156

Query: 424 GGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 245
           GGG I+ ISS     P    GAY  SK  +  +T+ +A E     I  NCVAPG V T  
Sbjct: 157 GGGRIINISSSLVAMPIPRYGAYTASKAAVEMMTRILAQELRGTQITANCVAPGPVATDM 216

Query: 244 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             A   SEA  E  + + P +R G+ E++A  VAFLASD+  ++  + V V GG
Sbjct: 217 FFA-GKSEAAVEAGVKSNPFERLGKVEDVAPLVAFLASDEGEWVNAQVVRVNGG 269


>UniRef50_Q7W7A0 Cluster: Probable 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; Bordetella|Rep: Probable
           3-oxoacyl-[acyl-carrier protein] reductase - Bordetella
           parapertussis
          Length = 248

 Score =  124 bits (300), Expect = 2e-27
 Identities = 82/228 (35%), Positives = 119/228 (52%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+ +RL +EGA +V+    E  V  A  SL  EG    GV   VA+ +          ++
Sbjct: 23  AVCRRLQAEGARIVVGDIGEERVLAAAASL-GEGAL--GVFLDVADRQSWAAAKRAVDAQ 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
              VDI+               +D + W  + DVN++ +WL  + A+  + +RG G I+ 
Sbjct: 80  GWQVDIVVNVAGIVRDRSLAKMSDAE-WSAVIDVNLRGTWLGCQSAFAWIGERGWGRIIN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S A +        Y  +K  ++GLT+  A E     I VN VAPGIV T   + + + 
Sbjct: 139 VASTAIFGAYGQAN-YSAAKAGIVGLTRTAALEGAKRGILVNAVAPGIVETAILADVPDQ 197

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
               E  L+ +PLKR  RPEEIA  +AFLASDDASY+TG+T+VV GGA
Sbjct: 198 VR--EGWLARMPLKRTARPEEIAAVIAFLASDDASYMTGQTLVVDGGA 243


>UniRef50_UPI00015BAF2E Cluster: short-chain dehydrogenase/reductase
           SDR; n=1; Ignicoccus hospitalis KIN4/I|Rep: short-chain
           dehydrogenase/reductase SDR - Ignicoccus hospitalis
           KIN4/I
          Length = 261

 Score =  124 bits (299), Expect = 2e-27
 Identities = 79/236 (33%), Positives = 119/236 (50%), Gaps = 9/236 (3%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A+    EGA V I SR+E NV +A++ L   G  V G    + + E R RL   A   
Sbjct: 22  AVAREFLKEGAKVFISSRREENVKRALEELSPLG-EVRGTTADLRSKEDRERLVGEARKA 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GGVD+               +T  + W++ + + ++S+  L K   PE+V+RG G +V+
Sbjct: 81  LGGVDVFVFNSGGPPAKA-FEETTLEDWEEAYKLLLESAAHLTKLVLPEMVERGWGRVVY 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I+S+A   P E L      +  + GL K +  E   + I  N V PG  +T+    +   
Sbjct: 140 ITSVAIKMPLEGLVLSNAVRVGIAGLMKTLVKEYAGKGITFNSVLPGYTLTERVKEVIKK 199

Query: 223 EAGAE--------KSLSN-VPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +A  E        + LS+ +PLKR   PEE+A AV FLAS+ ASY+ G ++ V GG
Sbjct: 200 KAEMEGKSYEEALRELSDAIPLKRLAEPEEVARAVVFLASEAASYVNGVSLQVDGG 255


>UniRef50_Q93HC0 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=4; Actinomycetales|Rep: 3-oxoacyl-(Acyl
           carrier protein) reductase - Streptomyces avermitilis
          Length = 313

 Score =  124 bits (299), Expect = 2e-27
 Identities = 72/228 (31%), Positives = 109/228 (47%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQS-LRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           A+  RL S+G  +  C R +      V+  +R  G  V      V +    R     A  
Sbjct: 86  AVVARLASDGYDIGFCYRSDDQAAALVEKEVRELGRRVLSRRVDVTDRTQVREFVTAAEE 145

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           + G    +            +L  DE  WD +   N+  ++ L +     ++KRGGG++V
Sbjct: 146 ELGPASAVVTSAGITRDSPLVLMPDED-WDAVLRTNLDGTYNLCRAVAFPMIKRGGGAVV 204

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            +SS+A          Y  SK+ ++G T+++A E     IR N VAPG + T   S +  
Sbjct: 205 TLSSVAGVAGNAGQTNYSASKSGIIGFTRSLAKEGGRHGIRANSVAPGFIDTDMTSELPP 264

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               A++ L  +PLKRFGRPE++A  VAFL S +A+YITG+   V GG
Sbjct: 265 KV--AKEMLGRIPLKRFGRPEDVAALVAFLLSSEAAYITGQVFQVDGG 310


>UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
           16129)
          Length = 256

 Score =  124 bits (299), Expect = 2e-27
 Identities = 76/233 (32%), Positives = 112/233 (48%), Gaps = 6/233 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK   SEGA VV     E    + V+ ++  G     V   V+     R + E AT +
Sbjct: 20  AAAKLFASEGAKVVAADIDEGGAQRTVEEIKEAGGEATAVKVDVSREPDVRAMVESATDR 79

Query: 583 FGGVDILXXXXXXXXXXX------SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 422
           +G +D+L                 S+++T E+ WD I  +N+K   L  K A P + ++G
Sbjct: 80  YGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINLKGVALGCKHAIPVMERQG 139

Query: 421 GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
            GSI+  +SI A        AY  +K  ++  ++ +A E     IRVNC+ PG V T   
Sbjct: 140 YGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLAVEWGPRGIRVNCICPGGVDTPMI 199

Query: 241 SAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           + + + E   +    N PL R  RPEEIA    FLAS++ASY+ G  + V GG
Sbjct: 200 APVISDERVMQSMRQNTPLGRLARPEEIASVALFLASEEASYLNGAIIPVDGG 252


>UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales
           bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales
           bacterium HTCC2150
          Length = 279

 Score =  124 bits (299), Expect = 2e-27
 Identities = 77/232 (33%), Positives = 118/232 (50%), Gaps = 2/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A R   +GA+VV+       + ++VQ L      V  +VC V   E+ + L  +A S 
Sbjct: 39  ACALRFLQDGANVVMADVNAEKLAESVQDLIEFDGAVSSMVCDVTKRENLQALVGLAVSN 98

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIV 407
           +G +D++            +  +D++ +D + DVN++ +++  + A  +++ +G GG I+
Sbjct: 99  YGNLDVMINNAGIAKVQDFLEISDDE-YDAVMDVNLRGAFIGTQIAGKQMIAQGKGGVII 157

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF-ASAIT 230
            +SSI A      L  Y +SK  +  LT   A      NIRV  + PG ++T   A  I 
Sbjct: 158 NMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPHNIRVCGIGPGTILTDMVADVIM 217

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            S       LS  P++R G P EIA   AFLASDDASY+TG+TV   GG  A
Sbjct: 218 TSPEARHNVLSRTPMERCGEPREIASVAAFLASDDASYMTGQTVYPDGGRMA 269


>UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Oceanobacillus iheyensis
          Length = 253

 Score =  124 bits (298), Expect = 3e-27
 Identities = 72/230 (31%), Positives = 107/230 (46%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA    SEGA V++    E      V+ + S       +  ++A  E   ++ + A   
Sbjct: 20  AIATLYASEGAKVIVADLNEEGAQSVVEEITSNNGVATAIKVNIAQKEDIDKMIDTAVDT 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +DIL           ++ D ++  WD IFD+N K      ++A P  +++  G IV 
Sbjct: 80  YGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRAMRKAIPIFLEKESGVIVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +S           AYG SK  ++GLTK       +  IR N +APG V T   S++   
Sbjct: 140 TASTGGLNGAHAGAAYGASKHAVIGLTKNTGYMYANSGIRCNAIAPGGVATNITSSLKGF 199

Query: 223 EA---GAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                G  K++  V + R G+PEEIA    FLASDDAS++ G  V   GG
Sbjct: 200 NEFGFGRTKAVQGV-MPRVGQPEEIAQVALFLASDDASFVNGTVVTADGG 248


>UniRef50_Q4JXS5 Cluster: Dehydrogenase related to short-chain
           alcohol dehydrogenases; n=3; Corynebacterineae|Rep:
           Dehydrogenase related to short-chain alcohol
           dehydrogenases - Corynebacterium jeikeium (strain K411)
          Length = 290

 Score =  124 bits (298), Expect = 3e-27
 Identities = 82/240 (34%), Positives = 124/240 (51%), Gaps = 13/240 (5%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS-------EGITVEGVVCHVANHEHRRRL 605
           A A +L + GA+VVI  RK   VG A + L++       +   V G+  HVA+ E  ++ 
Sbjct: 23  ATALQLAASGANVVITGRKPETVGPAAEELQAAARKQNPDAGRVIGIAAHVADPEAAKKA 82

Query: 604 FEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSS--WLLAK-EA-YPE 437
              A  +FG +D+L            +     ++  K+F +N      W  A  EA   +
Sbjct: 83  CTQAVEEFGRLDVLINNAGTNPAFGPVHKQSAEIMTKVFQINTIGPVIWTSAAIEADLGK 142

Query: 436 LVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPG 263
             + GG  G++V +SSI A    + +G Y  SK  LL LTK +A E     IRVN ++PG
Sbjct: 143 AARNGGPAGAVVNVSSIGALSMEDYIGVYNASKAALLHLTKQMARELA-PRIRVNSISPG 201

Query: 262 IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +V TK + A+      +  +L  +P  R G PE+IA A+AFLA+  +S++TGE +VV GG
Sbjct: 202 VVRTKLSEALWKENEDSTSTL--IPAGRIGEPEDIADAIAFLAAPTSSWLTGENLVVDGG 259


>UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein)
           reductase; n=3; Bacteria|Rep:
           3-ketoacyl-(Acyl-carrier-protein) reductase -
           Psychromonas sp. CNPT3
          Length = 244

 Score =  124 bits (298), Expect = 3e-27
 Identities = 77/227 (33%), Positives = 115/227 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA++  S GA+V+  +  E       + L   G   +G V +V +++    LF V    
Sbjct: 20  AIAEKFVSLGATVLGTATSEKGATAISEYLGDSG---KGFVLNVTDNDSIAALFAVIKKD 76

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           + GVDIL            +   D++ W+ I D N+   + ++K     ++K+  G I+ 
Sbjct: 77  YIGVDILVNNAGITRDNLLMRMKDDE-WNDIIDTNLTPIFKMSKAVMRPMMKKRAGRIIN 135

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I S+           Y  +K  ++G TK++A E     I VN VAPG + T    A+T+ 
Sbjct: 136 IGSVVGTMGNAGQANYAAAKAGVIGFTKSLAREIASRGITVNTVAPGFIETDMTKALTDE 195

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +   EK+L+NVP  R G   EIA  VAFLASD A+YITGET+ V GG
Sbjct: 196 QR--EKTLANVPAGRLGFASEIAATVAFLASDGAAYITGETIHVNGG 240


>UniRef50_A5V310 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Sphingomonas wittichii RW1|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Sphingomonas wittichii RW1
          Length = 248

 Score =  124 bits (298), Expect = 3e-27
 Identities = 77/232 (33%), Positives = 118/232 (50%), Gaps = 2/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A   RL SEGA VV     + N  K   ++ + G    G++C VA+      +     ++
Sbjct: 22  ACMARLASEGAIVV---GTDVNQAKLDDAVAAAGANAHGMICDVADQAAIDAMVADVVAR 78

Query: 583 FGGVDILXXXXXXXXXXXSIL-DTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           FGGV +L             L +   + WDK+  VNV+  +L+ +   P ++++GGGSIV
Sbjct: 79  FGGVHVLINNAGIGNPRRLRLHEQPPEDWDKVMGVNVRGVYLMQRAVIPHMLRQGGGSIV 138

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ++S  +++ T     Y  SK  +L +T+A A +   +NIR+N V PG   T     + N
Sbjct: 139 NMASTGSFRATALSSPYITSKGAVLMMTRAAAADYARDNIRINAVCPG---TTNTDILAN 195

Query: 226 SEAG-AEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           S A   E  ++  P  R G PEE+A  VAFLASD+A +I G   ++ GG  A
Sbjct: 196 SSAEMIEMLVARSPQARLGEPEEVAALVAFLASDEAPHIHGGAYLIDGGRSA 247


>UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=28; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 253

 Score =  123 bits (297), Expect = 4e-27
 Identities = 76/229 (33%), Positives = 115/229 (50%), Gaps = 3/229 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IAK     GA VV+   +     +   ++ S G     V   V        +   A  +F
Sbjct: 22  IAKHFAELGAKVVVADLRAEAAQQVAAAIESAGGQAIAVHVDVTQDASVADMVAAAVKRF 81

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +DIL            +L+TDE+ +D+++  NVKS +L A+ A P   ++GGG I+ I
Sbjct: 82  GRLDILVNNAGTTHKNQPMLETDEKTFDRVYATNVKSIYLGARHAVPLFRQQGGGVIINI 141

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI---T 230
           +S A  +P   L  Y  +K   + LTKA+A E   + IRVN + P +  T   +      
Sbjct: 142 ASTAGLRPRPGLSWYAGTKGAAITLTKAMAVELAPDKIRVNAINPVMGETGLLADFLPGA 201

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +SE   +K ++ +PL R  +P +IA A AFLASD+A +ITG  + V GG
Sbjct: 202 DSEEVRQKIIATIPLGRLSKPIDIAKATAFLASDEADFITGVALEVDGG 250


>UniRef50_Q0K243 Cluster: Short chain dehydrogenase; n=3;
           Cupriavidus|Rep: Short chain dehydrogenase - Ralstonia
           eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
           337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
           428 / Stanier337))
          Length = 255

 Score =  123 bits (297), Expect = 4e-27
 Identities = 71/231 (30%), Positives = 117/231 (50%), Gaps = 1/231 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A+ LG+ GA+VV+  R       A   L +EGI   G+ C +A+ +  R   E A + +
Sbjct: 25  MARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRATGIACDIADVDSVRAFAEQALAAY 84

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G VD L           S+L    +V+D     NV+ + +L     P+++ R  GSI+F+
Sbjct: 85  GRVDALVLNAAASGQPGSMLSQGPEVFDAAMAGNVRGNLVLVNALAPQMISRHDGSIIFM 144

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAITNS 224
           SSIAA + +  LG Y V+K  +    +++A E     I VN + PG V T+F+  A+   
Sbjct: 145 SSIAAKRGSAFLGMYSVTKAAIDQAVRSLALELGPSGINVNAINPGPVRTEFSRDALWGD 204

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
                +  + VP++R G   ++AG    LA+    +I G+++ V GG  A+
Sbjct: 205 PEREARLAAGVPMRRIGEASDVAGLAVLLAAPAGRFIHGQSIGVDGGLSAQ 255


>UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
           Short-chain dehydrogenase/reductase SDR - Halorubrum
           lacusprofundi ATCC 49239
          Length = 263

 Score =  123 bits (297), Expect = 4e-27
 Identities = 78/233 (33%), Positives = 110/233 (47%), Gaps = 2/233 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI   + + GA+VV  +R  + V       R  G+   G+   V + +    L E     
Sbjct: 33  AITLGMAAAGATVVPSARTAAEVEAVADEARDFGVEARGITADVTDDDDVEALVEEIVDA 92

Query: 583 FGGVDILXXXXXXX--XXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
           FG +DIL                + +    D + DVN++ ++   + A P L K  GGS+
Sbjct: 93  FGSLDILVNNAGFNPGDALGDPAEIESDAVDSVLDVNLRGAFRTLRAAGPHL-KEAGGSV 151

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           V ++S+A          Y  SK  L+GLTK+ A +   E +RVN VAPG V T     + 
Sbjct: 152 VNVASVAGEVGLPKQHPYVASKHGLVGLTKSAAMDWAPE-VRVNAVAPGYVATDLTETLQ 210

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
            +E   +  L   PL RF  P EIAG   FLASD AS++TGET+   GG  AR
Sbjct: 211 ENERLRQSILDRTPLDRFADPMEIAGPAVFLASDAASFVTGETLAADGGWTAR 263


>UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=9; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex
           aeolicus
          Length = 248

 Score =  123 bits (297), Expect = 4e-27
 Identities = 72/228 (31%), Positives = 116/228 (50%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATS 587
           AIA++L S G++V+I            + + ++ G+   GV  ++ + E   + FE   +
Sbjct: 22  AIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMNLLSEESINKAFEEIYN 81

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
              G+DIL             L      W+++  VN+  ++L+ + +  +++K+  G IV
Sbjct: 82  LVDGIDILVNNAGITRDKL-FLRMSLLDWEEVLKVNLTGTFLVTQNSLRKMIKQRWGRIV 140

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ISS+  +        Y  +K  L+G TK++A E    N+ VN VAPG + T   + +  
Sbjct: 141 NISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNAVAPGFIETDMTAVL-- 198

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           SE   +K    +PL RFG PEE+A  V FL S+ ASYITGE + V GG
Sbjct: 199 SEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITGEVIHVNGG 246


>UniRef50_Q13GE7 Cluster: Putative short-chain
           dehydrogenase/reductase; n=1; Burkholderia xenovorans
           LB400|Rep: Putative short-chain dehydrogenase/reductase
           - Burkholderia xenovorans (strain LB400)
          Length = 255

 Score =  123 bits (296), Expect = 6e-27
 Identities = 71/239 (29%), Positives = 122/239 (51%), Gaps = 7/239 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA  L  +GA VV     E  +      +  EG  ++ ++C V +     R+       
Sbjct: 17  AIAALLARQGAQVVGLDVNEQALADTRAVIEGEGGKLKALLCDVTDPASIDRVVRETIDA 76

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D+L            ++D  E++WD+ FD+N+KS +L+ K   P + ++ GG++V 
Sbjct: 77  YGRIDVLVNNVGVSAPGG-VVDMTEEIWDRQFDINLKSVFLMCKAVLPLMDRQRGGNVVN 135

Query: 403 ISSIAAYQPT-EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           +SS++A + + +P  AY  SK  L+  T+  A      N+R+NCV PG++ T     +  
Sbjct: 136 VSSLSALRYSGKPQIAYSASKAALIQFTRMAALMHSEHNVRLNCVIPGLITTPLVQRLAQ 195

Query: 226 SEAGAE------KSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
              G +      +  + VPL + G   ++A A AFLASD+A YIT   ++V GG+ + +
Sbjct: 196 QFGGGDYESYLKRRNAQVPLAQEGDAWDVANATAFLASDEARYITATEILVDGGSASTM 254


>UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Mycobacterium sp. (strain JLS)
          Length = 255

 Score =  123 bits (296), Expect = 6e-27
 Identities = 80/232 (34%), Positives = 112/232 (48%), Gaps = 2/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A  L   GA+V I  R      K V+   +EG  +  +   +   +   R+   A S 
Sbjct: 26  AFAFGLAQAGATVAISGRSAERNAKVVEEAAAEGFALHPITADITRQDDVDRMTAEAISA 85

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +DIL           S  D  E+ WD +FD+NVK+ W  +  A   + +RG GSIV 
Sbjct: 86  LGHLDILVNNAGTCYHAES-WDVTEEQWDSVFDLNVKALWACSLAAGAHMRERGSGSIVN 144

Query: 403 ISSIAAYQPTEPL--GAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           I S++      P    AY  SK  +  LTK++A E     IRVN +APG   T+ A    
Sbjct: 145 IGSMSGLIVNRPQMQPAYNASKAAVHHLTKSLAAEWGPLGIRVNALAPGYCKTEMAPV-- 202

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           +     +  + + P+ R+  PEEIA +V FLASD AS+ITG  +V  GG  A
Sbjct: 203 DKPEFKQHWIDDTPMLRYAMPEEIAPSVVFLASDAASFITGSVLVADGGYTA 254


>UniRef50_P80869 Cluster: Glucose 1-dehydrogenase 2; n=39;
           Bacilli|Rep: Glucose 1-dehydrogenase 2 - Bacillus
           subtilis
          Length = 258

 Score =  123 bits (296), Expect = 6e-27
 Identities = 71/229 (31%), Positives = 118/229 (51%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKE-SNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           AIA+R G E  +VV+    + S   + ++ ++  G     V   V+  E  + L + A  
Sbjct: 22  AIAERFGKEKMNVVVNYHSDPSGADETLEIIKQNGGKAVSVEADVSKEEGIQALLDTALE 81

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSI 410
            FG +D++              +   + W ++ DVNV  ++L AK A   ++K    G++
Sbjct: 82  HFGTLDVMVNNSGFNGVEAMPHEMSLEDWQRVIDVNVTGTFLGAKAALNHMMKNNIKGNV 141

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           + ISS+    P      Y  SK  +  +T+ +A     + IRVN +APG + T+ ++  T
Sbjct: 142 LNISSVHQQIPRPVNVQYSTSKGGIKMMTETLALNYADKGIRVNAIAPGTIATE-SNVDT 200

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             E   +K L  +P+K FG+PEE+A A A+L S++ASY+TG T+ V GG
Sbjct: 201 KKEESRQKQLKKIPMKAFGKPEEVAAAAAWLVSEEASYVTGATLFVDGG 249


>UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn)
           reductase precursor; n=1; Rhodopseudomonas
           palustris|Rep: Putative 3-oxoacyl-(Acyl carrier ptn)
           reductase precursor - Rhodopseudomonas palustris
          Length = 262

 Score =  122 bits (295), Expect = 7e-27
 Identities = 77/231 (33%), Positives = 116/231 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A RL  EGA V +    +  +G+  +SL      +  VV  V   E    L + A  +
Sbjct: 20  ATAARLAREGAYVYLSDIDQDALGRQAESLVDVAERISTVVADVTVPEQVSALIDGAARE 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +DIL            I +   + W ++F + V S +  ++ A P L+K   G+IV 
Sbjct: 80  RGRLDILINNAGMGAFGR-ITEVTPEAWHRVFGICVDSIFHASRAAIPHLIK-ARGTIVN 137

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +SI+         AY  +K  ++ LT+ +A +   + +RVN V PG++ T  +  + ++
Sbjct: 138 TASISGLFGDYGFAAYNAAKGAVINLTRNMALDYSRDGLRVNAVCPGLIATPLSLKLRDN 197

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
            A   +    +PL R G PEE+AGA+AFLASDDASYITG    V GG  AR
Sbjct: 198 AAVMAEYDRLIPLGRAGSPEEVAGAIAFLASDDASYITGVAFAVDGGLTAR 248


>UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanoculleus marisnigri
           (strain ATCC 35101 / DSM 1498 / JR1)
          Length = 249

 Score =  122 bits (295), Expect = 7e-27
 Identities = 76/231 (32%), Positives = 115/231 (49%), Gaps = 1/231 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK + +EG  VV+  R E    + V  ++  G  V  +   V   +  R L       
Sbjct: 21  ACAKDMAAEGGKVVVSGRNEKEGARIVNEIKEAGGEVIFIRADVTVEDDVRNLVAKTVEA 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIV 407
           FG +D+               + + + WD++ DVN+K  +L  K A  +++K+G GG+IV
Sbjct: 81  FGRLDVFVANSGVGSLGDPH-EVETEEWDRVLDVNLKGIFLCDKYAVQQMLKQGQGGAIV 139

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
              SI ++   + + AYG +K  +  LT+ +      + IR N VAPG + T   +A+  
Sbjct: 140 NTGSIHSFVAKQGVTAYGAAKGGVAMLTRTLGTSYAAQGIRANFVAPGYIDTPLLAALPR 199

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
                 K L   P+ R GRP E+A AV FLASDDAS ITG +++V GG  A
Sbjct: 200 EAYEELKKLH--PIGRLGRPMEVAKAVTFLASDDASNITGTSLLVDGGYTA 248


>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 254

 Score =  122 bits (294), Expect = 1e-26
 Identities = 79/236 (33%), Positives = 113/236 (47%), Gaps = 6/236 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK L   GA V +    E ++ KA +SL  E   V  +  +V   E      +    +
Sbjct: 18  ATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDRVFTITGNVTVEEDVENYVKQTVDR 77

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D+             I + D+  ++KI  +NV   +L  K    ++ K+G GSIV 
Sbjct: 78  FGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLKHVMKQMKKQGYGSIVN 137

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +S AAY  +  + +Y  SK  + G+TK  A E   + IRVN VAP  + T+  + I N+
Sbjct: 138 TASNAAYIGSAGMVSYIASKHAVAGITKTAALEVASDGIRVNAVAPAAIDTQMLADIQNN 197

Query: 223 ------EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
                 E   E     +P  RFG PEE+A  V FLASDDAS++ G    V GG  A
Sbjct: 198 LTPGEPEKSGEALKQGIPAGRFGAPEEVAQVVKFLASDDASFVNGSLYNVDGGMQA 253


>UniRef50_Q826D4 Cluster: Putative 3-oxoacyl-ACP reductase; n=1;
           Streptomyces avermitilis|Rep: Putative 3-oxoacyl-ACP
           reductase - Streptomyces avermitilis
          Length = 268

 Score =  122 bits (294), Expect = 1e-26
 Identities = 76/231 (32%), Positives = 121/231 (52%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A+   + GA V + +R    V +A + L   G+        VA+  H R L E+A + 
Sbjct: 24  AVAEAFAAAGAHVCVTARDADGVRRAAEELGGVGLAGS-----VADPAHPRELTELALAA 78

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D++            ++D D   W + F +NV++   L + A+   +   GG++V 
Sbjct: 79  FGRLDVVVNNAATNEPYGPLMDADPDRWREAFTINVEAPLRLVQCAWRAWMGEHGGAVVN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I +  A      +GAYG +K  LL LT+ +A E +   +RVN V+PG+V T+ A  +   
Sbjct: 139 ICTEGAGHVGPNVGAYGTTKAALLHLTRQLAGE-LAPKVRVNSVSPGLVRTELARFVW-- 195

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           E G ++  + +PL R G P +IA AV +LASD A +ITG  ++V GG   R
Sbjct: 196 EHGEDELAAGLPLGRIGHPADIARAVVWLASDAAEWITGADLLVDGGTRVR 246


>UniRef50_Q62AB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=14;
           Burkholderiales|Rep: 2-deoxy-D-gluconate 3-dehydrogenase
           - Burkholderia mallei (Pseudomonas mallei)
          Length = 256

 Score =  122 bits (294), Expect = 1e-26
 Identities = 80/232 (34%), Positives = 116/232 (50%), Gaps = 1/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ L   GASV +  R     G A  +L        G+   + +    +    +A S+
Sbjct: 28  ACARLLAQRGASVALVDRHPETAGIAA-TLEGGAARHSGMSLDLRDCSAAQAGVALAASR 86

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIV 407
           FGGVD+L           + LD  E  WD    +NVK+S+ +A+ A  +++    GG IV
Sbjct: 87  FGGVDMLVNSAGVALLDKA-LDVGEAAWDATMAINVKASFFVAQAAARQMIAGARGGRIV 145

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ++S A+    E   AY  SK  ++G+TKA+A E     I VN V+P IV T        
Sbjct: 146 NLASQASVVGLERHAAYCASKAAIVGMTKALALEWAPHGITVNAVSPTIVETALGKQAWA 205

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
            EAG E++   +P  RF +P+EIA  V +L SD A+ +TGE VV+ GG   R
Sbjct: 206 GEAG-ERAKREIPAGRFAQPDEIAALVLYLLSDAAAMMTGENVVIDGGYTVR 256


>UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Geobacter metallireducens GS-15|Rep: Short-chain
           dehydrogenase/reductase SDR - Geobacter metallireducens
           (strain GS-15 / ATCC 53774 / DSM 7210)
          Length = 257

 Score =  122 bits (294), Expect = 1e-26
 Identities = 68/232 (29%), Positives = 117/232 (50%), Gaps = 6/232 (2%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A+     GAS+V+CSR       A  ++R  G+  + + C +   +  + +     ++F
Sbjct: 27  MAEGFAEAGASLVLCSRNLEQCEDAAANIRKLGVECDALRCDIGEQDEVKAVVAHTMNRF 86

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +DIL            + DT  + WD+++  NV+ ++    E    ++  GGG+I+ I
Sbjct: 87  GKIDILVNNAGISWGGE-LQDTPLKKWDQLYSTNVRGNYFFTTEVVSPMIAGGGGNIINI 145

Query: 400 SSIAAYQPTEP----LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
            SI   + T+P      AY  +K  ++ LTK ++      NIRVN +APGI  T+ +  +
Sbjct: 146 VSIGGVRSTDPKVVTFPAYASTKGAIIALTKHLSRNWAKHNIRVNAIAPGIFPTEISKTL 205

Query: 232 TNSEAGAEKSL--SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                G +K++  + VPL R G  ++  GA  FLA+D + Y+TG  + V GG
Sbjct: 206 M---VGPQKAVMEAAVPLGRLGEKDDFKGAALFLAADASRYVTGSVLWVDGG 254


>UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 251

 Score =  122 bits (294), Expect = 1e-26
 Identities = 74/231 (32%), Positives = 112/231 (48%), Gaps = 1/231 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A  L  EGA VV+         K V+ ++ EG     V C V+  E  RRL E     
Sbjct: 20  ASALALAREGARVVVGDVNVEEGRKTVEDIKKEGGEALFVECDVSREEGARRLVEETVGA 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D+L           S+ +   + W + F VNV   +  ++ A PE+ K GGG I+ 
Sbjct: 80  FGRIDVLFNNAGINITEGSVPEMKVEDWRRTFAVNVDGIFWCSRYAIPEMRKNGGGRIIN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +S +++       AY  SK  ++ LT+A+A +   ENIRVN + PG++++         
Sbjct: 140 TASPSSFVGWAGNAAYIASKGAVMSLTRAMAMDHAKENIRVNAIVPGLILSPLGLNWVQQ 199

Query: 223 EAGAEKSLSNV-PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           +   E    ++ P+ R G PE++A  V FLA DDA + TG    + GG  A
Sbjct: 200 QEDPEAVKESIHPIGRPGYPEDVAPVVVFLAQDDAEFATGAPFFMDGGLVA 250


>UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase
           precursor; n=2; Clostridium difficile|Rep: Probable
           short chain dehydrogenase precursor - Clostridium
           difficile (strain 630)
          Length = 245

 Score =  122 bits (294), Expect = 1e-26
 Identities = 69/228 (30%), Positives = 117/228 (51%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATS 587
           A++K    EG +V++   K  N  K + ++ +E   +V+    +++N E    + +    
Sbjct: 18  AMSKAFAKEGYNVLVNFNKSENEAKELYTILNEKNFSVKLFKANISNREDVEDMVDYCIK 77

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           +FGG+D+L               TDE  WD + ++N+K S+  ++ A   ++    G+I+
Sbjct: 78  EFGGLDVLVNNAGVSQDKLFTDITDED-WDNMMNINLKGSFYCSQVALKYMISEKKGNII 136

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ISSI           Y ++K  ++G+TKA+A E    NIRVN +APG++ T   S    
Sbjct: 137 NISSIWGISGASCEVHYSITKAGIIGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGY-- 194

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +E   +  +   PL R G PE+IA    FLASD +++ITG+ +   GG
Sbjct: 195 NEEDIDALVEETPLMRLGTPEDIANCAIFLASDKSNFITGQVISPNGG 242


>UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Burkholderia ambifaria AMMD|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia cepacia
           (strain ATCC 53795 / AMMD)
          Length = 252

 Score =  122 bits (294), Expect = 1e-26
 Identities = 80/232 (34%), Positives = 109/232 (46%), Gaps = 2/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A     EGA V I +R+E    + V+ +   G     V   VA  E          + 
Sbjct: 21  ATAMLFAREGAKVAIAARREEEGRQVVREILDHGGEAIFVRTDVAQAEDCAAAVARTVAS 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DI             + DTDEQ W  + DVN+  ++L  K   PE++K GGGSI+ 
Sbjct: 81  FGKLDIAFNNAGITSFGRPVADTDEQAWSTVIDVNLTGTFLSMKYEIPEILKAGGGSIIN 140

Query: 403 ISSIAAYQPTEPLGA--YGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           +SS A        GA  Y  SK  ++GLT+A A E   E +RVN + P  V T    A  
Sbjct: 141 MSS-AYGLAGSAFGACSYHASKHGVIGLTRAAALEYAKEKLRVNAICPAFVATDMIGAFL 199

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
                A +  +  P+ R G   E A AV FLASD +++ITG T+ + GG  A
Sbjct: 200 EQPEQAAQLAALHPVGRMGTLAETAEAVVFLASDASTFITGTTLSIDGGMGA 251


>UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella baltica OS155|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella baltica OS155
          Length = 251

 Score =  122 bits (294), Expect = 1e-26
 Identities = 79/228 (34%), Positives = 113/228 (49%), Gaps = 1/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVG-KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           IA+    EGA ++I  R   +   + V  L++ G  V  +   V+     + L  +A  +
Sbjct: 22  IAEAFAIEGADLIINYRTNDDAAFRVVSKLKNLGRKVVAIRADVSKRSEIQNLIHLAQIE 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL               TDE  WD I   N+K  ++  +E +P +   GGG I+ 
Sbjct: 82  FGRIDILVNNAGINQRGWFNEVTDE-AWDMIMGTNLKGPFMCCQEVFPLMKANGGGRIIN 140

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS+A          Y VSK  L  LTK +A      N+ VN VAPG+V T       +S
Sbjct: 141 ISSVAGQYHGPKTVHYAVSKAGLNSLTKVLARYGAEYNVLVNAVAPGLVRTDQTIDEIDS 200

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
            AGA + L    LK+ GR E+I+ A  FLASD+  Y+TG+ + V+GGA
Sbjct: 201 PAGA-RVLDMTLLKKAGRIEDISSACVFLASDEQQYMTGQILAVSGGA 247


>UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Nocardioides sp. (strain
           BAA-499 / JS614)
          Length = 259

 Score =  122 bits (294), Expect = 1e-26
 Identities = 79/230 (34%), Positives = 117/230 (50%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A  +R   EGA VVI    ++   + V+ L    +    V   V + E    LF+ A   
Sbjct: 22  ATVQRFVQEGAKVVIGDIDDARGHQLVEQLGGADVATY-VHVDVTSKEQVDALFQTAKDA 80

Query: 583 FGGVDILXXXXXXXX-XXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           +G VDI             SILDTD   W K+ +VN+ S +L  K A P ++++G GSI+
Sbjct: 81  YGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSVYLCCKAALPHMLEQGRGSII 140

Query: 406 FISSIAAYQPTEPLG-AYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
             +S  A         +Y  SK  +L +T+ +  +   + +RVN + PG V T     + 
Sbjct: 141 NTASFVAVMGAATSQISYSASKGGVLSMTRELGVQFARQGVRVNALCPGPVNTPLLQELF 200

Query: 229 NSEAG-AEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             +A  A + L +VP+ RFG PEE+A AV FLASDD+S++T  T +V GG
Sbjct: 201 AKDAERAARRLVHVPMGRFGEPEEMASAVLFLASDDSSFMTASTFLVDGG 250


>UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1;
           Agrobacterium tumefaciens str. C58|Rep: Short chain
           dehydrogenase - Agrobacterium tumefaciens (strain C58 /
           ATCC 33970)
          Length = 249

 Score =  122 bits (293), Expect = 1e-26
 Identities = 79/231 (34%), Positives = 110/231 (47%), Gaps = 1/231 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A    ++GA+VVI +R E  + +    +R  G  V  V       E   RL + A   
Sbjct: 21  ATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAVAGDAGVAETHSRLADAAVGV 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+DI             + +   + WD + +VN+ S++L A+   P ++KRGGGSIVF
Sbjct: 81  FGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAFLGARYQIPPMLKRGGGSIVF 140

Query: 403 ISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            SS        P + AYG +K  L+GL K I  +     IR N + PG V T  A     
Sbjct: 141 TSSFVGTSAGIPGMSAYGTAKAALMGLVKGITADYAINGIRANALLPGGVDTPAA----G 196

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
             A  E +     +KR  +PEEIA A  FLAS  AS++ G  +   GG  A
Sbjct: 197 DPAQKEWAAGLHAMKRIAQPEEIAQAALFLASPMASFVAGAALFADGGNAA 247


>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Leptospira interrogans
          Length = 254

 Score =  122 bits (293), Expect = 1e-26
 Identities = 74/227 (32%), Positives = 116/227 (51%), Gaps = 2/227 (0%)
 Frame = -3

Query: 757 AKRLGSEGASVVICS-RKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           A  L   GA++VI    +ES+   A +  +  G+   G+  +V++ +   +  +    +F
Sbjct: 23  ALTLAKAGANLVIADLNEESSKATADEISKQTGVKAIGIGTNVSDVDSAAKAIQACVDEF 82

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKR-GGGSIVF 404
           G VDIL            +    EQ WD +  VN+  ++   + A   ++K   GGSI+ 
Sbjct: 83  GSVDILVNNAGITKDTLLMRMKKEQ-WDAVIAVNLTGTFNCTQAAIKFMMKNPNGGSIIN 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SSIA          Y  SK  ++G TKA+A E     +R N +APG + T+   AI   
Sbjct: 142 LSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVRCNAIAPGFIATEMTDAIPEK 201

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              A   ++ +PLKR G+PE+IA  +AFLASD +S+ITG+ + V GG
Sbjct: 202 IRTA--MVAAIPLKRAGQPEDIANTIAFLASDISSFITGQVIEVNGG 246


>UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|Rep:
           Glucose 1-dehydrogenase - Thermoplasma volcanium
          Length = 261

 Score =  122 bits (293), Expect = 1e-26
 Identities = 73/198 (36%), Positives = 104/198 (52%), Gaps = 9/198 (4%)
 Frame = -3

Query: 634 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLA 455
           V N E  +   E  T K+G +DIL             L T  ++W +I DVNV  S+L+A
Sbjct: 54  VTNEEEVKEAVEKTTKKYGRIDILVNNAGIEQYSPLHL-TPTEIWRRIIDVNVNGSYLMA 112

Query: 454 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 275
           K   P ++  G GSI+ I+S+ +Y  T+   AY  SK  LLGLT+++A +     IR N 
Sbjct: 113 KYTIPVMLAIGHGSIINIASVQSYAATKNAAAYVTSKHALLGLTRSVAIDYA-PKIRCNA 171

Query: 274 VAPGIVVTKFASAITNSEAGAEKSL---------SNVPLKRFGRPEEIAGAVAFLASDDA 122
           V PG ++T         E G +++             P+ R GRPEE+A  VAFLASD +
Sbjct: 172 VCPGTIMTPMVIKAAKMEVGEDENAVERKIEEWGRQHPMGRIGRPEEVAEVVAFLASDRS 231

Query: 121 SYITGETVVVAGGAPARL 68
           S+ITG  + V GG  ++L
Sbjct: 232 SFITGACLTVDGGLLSKL 249


>UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Geobacillus kaustophilus
          Length = 256

 Score =  121 bits (292), Expect = 2e-26
 Identities = 76/234 (32%), Positives = 118/234 (50%), Gaps = 7/234 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGI--TVEGVVCHVANHEHRRRLFEVAT 590
           A A RL  EGA+VV+  R    + + VQ +   G+    +     V +HE  R L     
Sbjct: 20  ATAVRLAQEGATVVLVGRTAVKLEETVQDITRLGVPGVADRFAADVTDHEQVRALAAYVQ 79

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-----R 425
           +++G + +L             L+  EQ WD +  VN+KS +L+++   P +++     R
Sbjct: 80  NRYGDLHVLVNNAGISTHTKW-LELTEQEWDDVQRVNMKSVFLVSQTLAPLMIEGAKRER 138

Query: 424 GGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF 245
              +IV ++S++ +Q    +  Y  +K  ++ LTK++A E     IRVN V+PG V T  
Sbjct: 139 ANRAIVNVASLSGHQAGAEIPHYSAAKAGVINLTKSLALELAPYGIRVNSVSPGFVETPL 198

Query: 244 ASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                 +E   +    N  L R G PEEIA  +AFLAS +ASY+TG  V+V GG
Sbjct: 199 TERGLQNERFVKAIERNTALGRVGAPEEIANVIAFLASSEASYMTGSDVLVDGG 252


>UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1;
           Planctomyces maris DSM 8797|Rep: Putative
           uncharacterized protein - Planctomyces maris DSM 8797
          Length = 258

 Score =  121 bits (292), Expect = 2e-26
 Identities = 72/230 (31%), Positives = 121/230 (52%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS-EGITVEGVVCH--VANHEHRRRLFEVA 593
           A   RL  EGA V +  R  S    A ++LR  E +   G++    V+      R+    
Sbjct: 29  ACCLRLAQEGARVAVSYR--SGKADAAETLRQIEALGGSGMIVQSDVSVETEVDRMVSEV 86

Query: 592 TSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
            ++ G +++L              + D   W ++ DVN+  ++L+     P ++KR  G 
Sbjct: 87  EAQLGDIELLVNNSGTFIYQSHE-ELDLSAWQQMLDVNLTGTFLVTWRVKPGMLKRQFGR 145

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           IV +SS++  QP     AY VSK  ++  T++IA     +NIRVN +APG++ T+  S +
Sbjct: 146 IVNLSSLSGLQPRPKSIAYAVSKAGVISFTQSIATAWARDNIRVNAIAPGLIETEILSTV 205

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             S+   EK +   P+ R G PEE+A  V+FL S+++++ TG+T+V++GG
Sbjct: 206 --SQEDLEKIIEATPIPRMGTPEEVAAIVSFLLSEESNFTTGQTMVLSGG 253


>UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Vibrio cholerae
           623-39|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Vibrio cholerae 623-39
          Length = 256

 Score =  121 bits (292), Expect = 2e-26
 Identities = 72/232 (31%), Positives = 122/232 (52%), Gaps = 2/232 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           I++    +GA V+I  R    + + +  L   G     ++C++ N E   RLF+ A S  
Sbjct: 28  ISQVFSVQGARVIIVGRDSERLTQTLDIL--SGDEHHAIICNLTNPEDIERLFDEAFSLV 85

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPEL-VKRGGGSIVF 404
           G +D +            +    E  +D++F  NVKS+  +AK    +    + G S++F
Sbjct: 86  GEIDAVVHCAGIQKTLP-LQAIKEIDFDEVFSTNVKSAQFIAKSYRKKSRYNKSGSSLIF 144

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS+AA      +  Y  SK  LLGL++++A+E     IRVNC++PG+V+T+ A  + + 
Sbjct: 145 LSSVAAACGEPAISTYSASKAALLGLSRSLASELARNKIRVNCISPGVVLTEMAEKLFSQ 204

Query: 223 EAGAEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
               +  L  N  +  FG+PE++A A  +LASD + ++TG T+ V GG  A+
Sbjct: 205 LTTEQYELILNKHMIGFGQPEDVANAALYLASDLSRWVTGSTLYVDGGYSAQ 256


>UniRef50_A1RDP9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Arthrobacter
           aurescens TC1|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Arthrobacter aurescens
           (strain TC1)
          Length = 257

 Score =  121 bits (292), Expect = 2e-26
 Identities = 88/238 (36%), Positives = 121/238 (50%), Gaps = 11/238 (4%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA++L  EGA+VV   R E+    A++ L  +   +  VV  VA+    R       +K
Sbjct: 21  AIAEKLLKEGATVVALDRDEA----ALERLIGQHPEMVPVVMDVADEASVRSGMAEIDAK 76

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK----RGGG 416
           FG +D L              D     WD++F VN    +L+++ A P L K    RG  
Sbjct: 77  FGRLDTLVNNAGIVKGSNFD-DVSVAEWDQVFAVNSTGPFLVSQAARPLLEKGAAARGDD 135

Query: 415 S---IVFISSIAAY----QPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
           S   IV I+S+ A+        P   Y  SK  LL  TKA+A ET    IRVN VAPG +
Sbjct: 136 STSAIVNITSVEAHIVIASSGHPQVHYNASKGALLMFTKALAIETAASKIRVNAVAPGFI 195

Query: 256 VTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            T F  ++  ++   +  L   PL R GRP ++A AVAFLASD+AS++TG T+ V GG
Sbjct: 196 ETPFTKSVLENQDAVKFLLDRTPLGRIGRPSDVANAVAFLASDEASWVTGTTIHVDGG 253


>UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Moorella thermoacetica (strain ATCC 39073)
          Length = 253

 Score =  121 bits (291), Expect = 2e-26
 Identities = 76/232 (32%), Positives = 118/232 (50%), Gaps = 5/232 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVIC---SRKES-NVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEV 596
           A+A      GA+VVI    S K + ++ + ++ +  + + V G    V++      +   
Sbjct: 21  AMALGFARNGANVVIHYNNSEKAALSLAQEIEQMGKKSLVVRG---DVSDKNQVDAMVSK 77

Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
              +FG +D+L              + DE +WD+I +VN+KS +L+ K  +P +  +G G
Sbjct: 78  IKERFGRIDVLINNAGSMIKRARFEEVDEALWDRIINVNLKSVFLVTKAVFPMMKAQGKG 137

Query: 415 SIVFISSIAAYQPTEPLG-AYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
            I+ I+S+AA          Y  +K  +   T+A+A +    NI VN +APG++ T F +
Sbjct: 138 KIINITSVAAKNGGGAGSITYATAKGGISTFTRALARDLADYNILVNAIAPGLIRTPFHN 197

Query: 238 AITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                    EK  S + LKR G PE+I GA  FLASD A YITGET+ V GG
Sbjct: 198 PEITPPQVFEKMASEILLKRAGTPEDIVGAALFLASDYADYITGETIDVNGG 249


>UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified
           Gammaproteobacteria (miscellaneous)|Rep: Oxidoreductase
           - gamma proteobacterium HTCC2207
          Length = 253

 Score =  121 bits (291), Expect = 2e-26
 Identities = 80/233 (34%), Positives = 109/233 (46%), Gaps = 6/233 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A  ++  SEGA V++           V  L +       V   VA  +    +       
Sbjct: 20  AAVRKFVSEGAKVMLADINTDITQPLVNELGAYRCAC--VAVDVAEADQVENMVRTTVDT 77

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D+            SI+DTD    DK+  VNV+  WL      P +   GGGSI+ 
Sbjct: 78  FGSIDVFVANAGTEGKIGSIMDTDVSNLDKVLAVNVRGVWLGLHYVMPVMRDGGGGSIII 137

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN- 227
            SS A  Q +    AY  SK  ++GL +  A E+    IRVN V PG V T+   +I + 
Sbjct: 138 TSSGAGVQGSPNTAAYNTSKHAVIGLMRCAALESAQFGIRVNTVNPGAVETRMMESIEDG 197

Query: 226 -SEAGAEKSLSNV----PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            +EAGA    + V    PL R+G+PEEIA  + FL SDD+SY TG   +V GG
Sbjct: 198 FAEAGAGDFRAMVEAVTPLGRYGQPEEIANMMVFLGSDDSSYCTGSVYMVDGG 250


>UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2143
          Length = 259

 Score =  121 bits (291), Expect = 2e-26
 Identities = 75/236 (31%), Positives = 109/236 (46%), Gaps = 7/236 (2%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A     EG +VV+    +    + V ++++ G     V C V      + L E   S +G
Sbjct: 24  AAAFAREGLNVVVADMDKDGGEETVAAIKAAGGNAIFVPCDVTKESDVQWLIETTCSTYG 83

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
            VD              +    E  +D I  VNVK  WL  K    +++ +GGG+IV  S
Sbjct: 84  SVDYAFNNAGIDIEKGELSKGTEDEFDSIMAVNVKGVWLCMKHQITQMITQGGGTIVNTS 143

Query: 397 SIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF---ASAITN 227
           SI        +  Y  SK  ++GLTK+ A E     IR+N V PG++ T     +     
Sbjct: 144 SIGGLGAAPNMSIYCASKHAVIGLTKSAAVENARNGIRINAVCPGVIDTNMFNRSRMFDR 203

Query: 226 SEAGAEKSLSNV----PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           SE  A ++ + V    P+ R G  EEI+ AV +L SD AS+ITG T+ V GG  A+
Sbjct: 204 SEVSASETRARVNAIHPMDRIGTAEEISDAVLYLCSDGASFITGHTLSVDGGLNAK 259


>UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
           reductase; n=21; Bacteria|Rep:
           3-oxoacyl-(Acyl-carrier-protein) reductase -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 248

 Score =  120 bits (290), Expect = 3e-26
 Identities = 67/228 (29%), Positives = 115/228 (50%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRK-ESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           AIA +  +EGA V I     +  V   V+ L+  G+       + A+ +    + E   +
Sbjct: 21  AIAYKYATEGADVAITDLNIDEGVQAFVEELKGLGVRAAAYASNAADFDAAHTVVEQIKA 80

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
            FG +DIL            +  T++Q WD + +VN+KS++ +     P ++ +  GSI+
Sbjct: 81  DFGRIDILVNNAGITRDGLMMRMTEQQ-WDAVINVNLKSAFNMIHAVTPIMMGQRTGSII 139

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ++S+           Y  SK  ++GL K++A E     +R N +APG ++T   + +  
Sbjct: 140 NMASVVGVSGNAGQSNYSASKAGMIGLAKSVAKELGSRGVRANAIAPGFIITDMTAVL-- 197

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           SE   ++  + +PL+R G PE++A    FL SD +SY+TG+ V V GG
Sbjct: 198 SEEVKKQWAAQIPLRRGGTPEDVANVATFLGSDLSSYVTGQVVHVCGG 245


>UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Candidatus Nitrosopumilus maritimus
           SCM1|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Candidatus Nitrosopumilus maritimus SCM1
          Length = 269

 Score =  120 bits (290), Expect = 3e-26
 Identities = 76/229 (33%), Positives = 113/229 (49%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK L   GA+V I  +    V + ++ + SE      +V  V   E  +   +    K
Sbjct: 42  ATAKVLSENGANVAITGK----VQERLEKVSSEISNSFAIVADVRKTEDVKNAIKKIVEK 97

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL            + + D++ W+++ DVN+   + + KEA P L K  G SI+ 
Sbjct: 98  FGRLDILVNNAGVFPKIKKLHEIDDEEWNEVLDVNLTGQFRVTKEAIPHLQKTSG-SIIN 156

Query: 403 ISSIAAYQPTEPLGA--YGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           ISS A  +  +   A  Y  +K  L+ LTK  A E   + IRVNC+ PG+V T       
Sbjct: 157 ISSDAGLKAYQGFNADAYSATKAALIVLTKCWALEYSKDKIRVNCICPGVVDTDMTKPFV 216

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            ++   +   +  PL R G PEE+A AV + ASDDA++ TG  + V GG
Sbjct: 217 KTQKDRDFMNAEHPLGRIGEPEEVAKAVLYFASDDAAWTTGAILAVDGG 265


>UniRef50_Q98H65 Cluster: Short chain dehydrogenase or
           3-ketoacyl-CoA reductase; n=2; Alphaproteobacteria|Rep:
           Short chain dehydrogenase or 3-ketoacyl-CoA reductase -
           Rhizobium loti (Mesorhizobium loti)
          Length = 248

 Score =  120 bits (289), Expect = 4e-26
 Identities = 78/229 (34%), Positives = 118/229 (51%), Gaps = 2/229 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVI-CSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           IAKRL +EGA+VV+  +       + V+ + + G     V   VA      ++FE A   
Sbjct: 22  IAKRLAAEGAAVVVNYATSREAAERTVKEIVAAGGKATAVQGDVAEAAEVEKMFEAAEIA 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG   IL              +  E  + ++FD NV  + L  K A     + GG SIV 
Sbjct: 82  FGKPSILINNAATASFGT-FEEASEADYRRLFDTNVLGTILTTKAAMRHFPETGG-SIVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I +I+++ P      Y  SK  +  LT +++ E    NIRVN VAPG   T+    +  +
Sbjct: 140 IGTISSWNPVPNTSLYSASKAAIDTLTLSLSRELGARNIRVNIVAPGYTHTEMTEGMVGT 199

Query: 223 EAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           + G    ++ VPL +RFG+P++IA  VAFLASD+A+++TGE +  +GGA
Sbjct: 200 DFG-NMLIAGVPLGQRFGKPDDIAPTVAFLASDEAAWLTGERINASGGA 247


>UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Marinomonas sp. MED121|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MED121
          Length = 255

 Score =  120 bits (289), Expect = 4e-26
 Identities = 67/232 (28%), Positives = 113/232 (48%), Gaps = 4/232 (1%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           AK+   +GA + +C    + +      L  +G  V    C V+N +  +   +   + FG
Sbjct: 23  AKQFAQQGAKLALCDLNVAALNDLGTELIEQGYEVFSQPCDVSNEQEVQSFIDNTAAHFG 82

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
            +D+            ++ D D + ++++ D+NVK  +L  K   P ++K+GGG+I  +S
Sbjct: 83  RLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYLCMKYQIPHMIKQGGGAICNMS 142

Query: 397 SIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAIT 230
           S+A       + AY  SK  ++GLTK++A+E     IRVN V P I +T    +    + 
Sbjct: 143 SVAGISGAPFMSAYAASKHAVIGLTKSVAHEYGRAGIRVNSVCPYITMTDMVEQHLKTLD 202

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           N E    K      L+R  +P E+A  + F    + SY+TG+ +VV GG  A
Sbjct: 203 NREEVLAKYSKASALRRVAQPNEVAKVMLFACDKNNSYMTGQELVVDGGMTA 254


>UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=3; Flavobacteriaceae|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Leeuwenhoekiella blandensis MED217
          Length = 246

 Score =  120 bits (289), Expect = 4e-26
 Identities = 77/228 (33%), Positives = 116/228 (50%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA++    G  V I  R E    +A  +L   G  V  +V  + N E   +L +     
Sbjct: 18  AIARKFCDAGYKVYIIGRNEEKTRQAADNL---GELVVPIVFDLNNLEAIPKLIDELLQA 74

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +D+L               TD + +D+I   NVKS + +++E    +    GGSIV 
Sbjct: 75  TGKIDVLVNNAGINMKKDFAEVTDAE-FDRILHTNVKSVFAISREVVKSMKGNYGGSIVN 133

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF-ASAITN 227
           ISS+AA      + AY  SKT + G+T+A+A +    NIRVNCVAPG + T   A A+ +
Sbjct: 134 ISSMAAQYGIPQVIAYTASKTAIEGMTRAMAVDLAQYNIRVNCVAPGFIKTPMTAKALNS 193

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            +   ++  S  P+ + G PE+IA AV +LA  ++ +ITG  + V GG
Sbjct: 194 DKQRKDRVFSRTPMGKMGAPEDIADAVFYLAGKESKFITGTVLCVDGG 241


>UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=9;
           Bacteria|Rep: 2 deoxy-D-gluconate 3-dehydrogenase -
           Clostridium acetobutylicum
          Length = 260

 Score =  120 bits (288), Expect = 5e-26
 Identities = 72/225 (32%), Positives = 115/225 (51%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A  L   GA + I +   +N  +  + +  EG  VE     ++  E    +F+     +G
Sbjct: 34  ALALAKAGADLFIVTHG-TNWDETRKLIEDEGRKVEFYKADLSKKESIPGIFDKCMELYG 92

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
            +DIL                DE  W+ I + N+ S + L++ A   ++K+G G I+ I+
Sbjct: 93  RLDILVNNAGTIRRAPITEYRDED-WEYIINTNLNSIYHLSQRAAKIMIKQGSGKIINIA 151

Query: 397 SIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEA 218
           S+ ++Q  + +  Y  SK  + GLTKA ANE   +NI++N +APG +VTK   AI N E+
Sbjct: 152 SMLSFQGGKFVPPYTASKHGVAGLTKAFANELADKNIQINAIAPGYIVTKNTEAIRNDES 211

Query: 217 GAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              + LS +P  ++G P ++ G V FLAS  + YI G  + V GG
Sbjct: 212 RNNEILSRIPAGKWGYPFDVMGTVVFLASRASDYINGHILAVDGG 256


>UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1;
           Bacillus licheniformis ATCC 14580|Rep: Putative
           uncharacterized protein - Bacillus licheniformis (strain
           DSM 13 / ATCC 14580)
          Length = 248

 Score =  120 bits (288), Expect = 5e-26
 Identities = 74/228 (32%), Positives = 111/228 (48%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+ L  +GA+VVI    E  +      L +E      V    +  E    L   A  +
Sbjct: 20  AIAELLADKGANVVINGTNEELLKSLCTQLNTERKCASYVAGDASLPETASLLIAEAKQR 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL           ++ DT  + W ++ D+N+  ++L+ +   PE++ +GGG IV 
Sbjct: 80  FGRIDILVNNAGVNLRKTTV-DTSLEEWKRVIDLNLTGTFLMCQAVIPEMITQGGGKIVN 138

Query: 403 ISSIAAYQPTEPLG-AYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           +SS  +  P      AYG SK  +  LT  +A E     I VN V PG + T  +   + 
Sbjct: 139 MSSTTSKTPHHNASPAYGASKAGINYLTMHLAKELAEHRIHVNGVCPGPIETDMSKQWSE 198

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               A   +  +PLK  G PE +A  VAFLASD + ++TGET+ + GG
Sbjct: 199 EYRAAV--VERIPLKMLGSPEHVANVVAFLASDKSDFMTGETININGG 244


>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Bacillus coagulans 36D1|Rep: Short-chain
           dehydrogenase/reductase SDR - Bacillus coagulans 36D1
          Length = 262

 Score =  120 bits (288), Expect = 5e-26
 Identities = 70/233 (30%), Positives = 116/233 (49%), Gaps = 9/233 (3%)
 Frame = -3

Query: 751 RLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
           +L + GA+VV+    +    +    +R  G     V   V+  +  +     A   +G +
Sbjct: 27  KLAAGGANVVVADLSDELGEETAGKIRENGGEAIFVRTDVSKSKDVQHYVRTALDTYGKI 86

Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSI 392
           DIL            ++D  E+V+DK+  +NV+  +L  K   P ++ +  G+IV  +S+
Sbjct: 87  DILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVFLGMKYVLPHMISQKSGTIVNTASV 146

Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
           A    T  + AYG SK  ++G+TK    E     +RVN V PG+V T+    I N  AG 
Sbjct: 147 AGLVGTPEMVAYGASKHAVIGMTKTAGIEAAPSGVRVNAVCPGVVDTEMMRKIENGFAGG 206

Query: 211 EKS---------LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           + +          ++ P  R+ +PEE+A  + +LASD +S+I G+TVV+ GGA
Sbjct: 207 DSAAAEQTRQQMAASAPTGRYTQPEEVANVLLYLASDLSSHIIGQTVVIDGGA 259


>UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductase;
           n=10; Bacteria|Rep: 3-oxoacyl-acyl carrier protein
           reductase - Deinococcus radiodurans
          Length = 254

 Score =  119 bits (287), Expect = 7e-26
 Identities = 72/228 (31%), Positives = 114/228 (50%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVI-CSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           A+A RL  +G +V +   R E+   +    +R+ G   +     ++   +   L E   +
Sbjct: 26  AMALRLAQDGFTVAVHYGRGEAEAQQVAADIRAAGGAAQVFGADLSQPANAGTLVEDVIA 85

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
             G +D+L           +I   DE  WD +   N+ S++   + A   ++K   G IV
Sbjct: 86  ALGRLDVLVNNAGITRDGLAIRMKDED-WDAVLQTNLSSAFAACRAALKHMMKNRSGRIV 144

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            +SS+ A         Y  SK  L+GLT+A+A E     I VN +APG + +   + +  
Sbjct: 145 NVSSVVALAGNPGQANYVASKAGLIGLTRALAKEYGGRGITVNAIAPGFIESDMTAKL-- 202

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            E   ++  +N+PL RFG+PEE+A  VAFLAS+ A YITG+T+ V GG
Sbjct: 203 PEDTKKQYQANIPLARFGQPEEVAALVAFLASEGAGYITGQTIGVDGG 250


>UniRef50_Q7WM80 Cluster: Probable short chain dehydrogenase; n=1;
           Bordetella bronchiseptica|Rep: Probable short chain
           dehydrogenase - Bordetella bronchiseptica (Alcaligenes
           bronchisepticus)
          Length = 259

 Score =  119 bits (287), Expect = 7e-26
 Identities = 68/231 (29%), Positives = 113/231 (48%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A   G  GA V++   +++   +AV+ LR++GI   G V  V++            +  
Sbjct: 30  MAATAGQAGARVIVNDVRDAACNEAVEGLRAQGIDARGAVFDVSSAAAVSDAVAALAAAR 89

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
              D+L            +++ D  VW  IFDV+V  ++  A+   P ++ +GGG I+  
Sbjct: 90  WSPDVLVSNAGNQNRAP-VVEQDPAVWQSIFDVHVNGAFHCARAVLPGMISQGGGRIIIT 148

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           SS+AA      + AY  +K  L   T+A+A E   + +  N +APG V T F +A+   E
Sbjct: 149 SSVAALACMPGIAAYSAAKGALAAFTRALAVEYGGQGVTCNALAPGFVRTGFTTALQERE 208

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
              +   S VPL R+  P++IA AV +LAS    ++ G  + + GG  A +
Sbjct: 209 QFNDFLKSQVPLGRWADPDDIAPAVVYLASQAGRFVNGHVLAIDGGLLAHM 259


>UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain
           dehydrogenase; n=1; Saccharopolyspora spinosa|Rep:
           Putative oxidoreductase, short chain dehydrogenase -
           Saccharopolyspora spinosa
          Length = 240

 Score =  119 bits (287), Expect = 7e-26
 Identities = 85/235 (36%), Positives = 115/235 (48%), Gaps = 18/235 (7%)
 Frame = -3

Query: 724 VICSRKESNVGKA-VQSLRSEGITVEGV------------VCHVANHEHRRRLFEVATSK 584
           VI +   S +G+A V  LRSEG +V  V             C VA+      + + A + 
Sbjct: 8   VIVTGAASGIGRATVGLLRSEGASVVSVDLRDPGDDPSFIKCDVADSGSVAAMVDEAVTG 67

Query: 583 FGGVD-ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
            GG+D ++            +LD  E  WD    VNVKS +L +K A P L   GGGSI 
Sbjct: 68  LGGLDAVVNVAGIQRSGAVEVLD--ETDWDDQLRVNVKSCFLTSKYAVPHLRAAGGGSIT 125

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
             +S+A  +    + AY  SK  ++  T+ +A E   +NIR NC+ PG V T F   +  
Sbjct: 126 TTASLAGLKGFAGMTAYSASKGAVIAFTRTLAVEVAADNIRANCLCPGWVDTPFNDPVIT 185

Query: 226 SEAGAEKSL----SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            E G E  L    +NVPL R   P E+A   AFL SD ASY+TG+ + V GG  A
Sbjct: 186 FEGGREAHLANVKANVPLSREAAPPELAKWHAFLVSDAASYMTGQAITVDGGLSA 240


>UniRef50_Q4IUB1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Azotobacter vinelandii
           AvOP
          Length = 263

 Score =  119 bits (287), Expect = 7e-26
 Identities = 80/237 (33%), Positives = 118/237 (49%), Gaps = 11/237 (4%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNV-GKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           +A+ L +EG  VV+ +R    V  +A +   + G+   GV C V++ E    L    T +
Sbjct: 23  VAEGLATEGVRVVLSARGADRVIVEAARIADTYGVETLGVACDVSSKEGVETLIAAVTDR 82

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG DIL            +   DE+ W   +D++V ++  LA+   P +  RGGG I+ 
Sbjct: 83  FGGADILINNAGTGSNETVMQAPDEK-WQHYWDLHVMAAVRLARGLAPGMKMRGGGVILH 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT-------KF 245
            +SI A QP      Y V+K  L+  +K +A E + +NIRVN V PG+V+T       K 
Sbjct: 142 NASICAVQPLGYEPIYNVTKAALMMFSKNLATELIKDNIRVNTVNPGLVLTPDWIKTAKE 201

Query: 244 ASAITNSEAGA---EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            +A T+ E  A     +  +  +KRF  P E+A    FL S+ ASY  G T  V GG
Sbjct: 202 LTATTDGEWQAYLDRIAAESADIKRFANPAEVADFFVFLCSERASYSVGSTYFVDGG 258


>UniRef50_A5VCG8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Sphingomonas wittichii RW1|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
          Length = 265

 Score =  119 bits (287), Expect = 7e-26
 Identities = 78/236 (33%), Positives = 116/236 (49%), Gaps = 5/236 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A RL  EGA V++ +R    +G     +R++G   E V     +      +   A  +
Sbjct: 36  ATAIRLAGEGARVMLGARSPDRIGAVADQIRAKGGQAETVCFDATDDASIAAMVAQAADR 95

Query: 583 FGGVDILXXXXXXXXXXXSILDTDE-----QVWDKIFDVNVKSSWLLAKEAYPELVKRGG 419
           FGG+D +             +DTD      +V+DK   VN++   L A+ A P LV+RGG
Sbjct: 96  FGGLDGMFVNMAELTLHK--VDTDAVSVPLEVFDKAVAVNLRGHLLCARHAVPLLVERGG 153

Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
           GSIVF SS AA+   +   +Y V+K  L  L + +A     + +R N V+PG+V+    S
Sbjct: 154 GSIVFTSSSAAFMGRDRGISYTVTKHALTALMRHVATTWGKQGVRSNIVSPGLVL----S 209

Query: 238 AITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
               +    +K L+N P  R G PE++A  VA L S D  +I G+ + V GG   R
Sbjct: 210 EKNRNHPEMDKVLANTPSPRLGEPEDLAAVVAMLMSSDGEWINGQILCVDGGVVMR 265


>UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=18; Corynebacterineae|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium sp. (strain
           KMS)
          Length = 253

 Score =  119 bits (287), Expect = 7e-26
 Identities = 73/229 (31%), Positives = 114/229 (49%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ L  EGA+VV+         K    ++ EG     V   V++ +  + +     S+
Sbjct: 25  AYAEALAREGAAVVVADINVDGAQKVADGIKGEGGNALAVRVDVSDPDSAKEMAAQTLSE 84

Query: 583 FGGVDILXXXXXXXXXXXS--ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
           FGG+D L              ++  D   + K   VN+  + +  +  Y ++ KRGGG+I
Sbjct: 85  FGGIDYLVNNAAIFGGMKLDFLITVDWDYYKKFMSVNLDGALVCTRAVYRKMAKRGGGAI 144

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           V  SS AA+  +     YG++K  + GLT+ +A E   +NIRVN +APG + T+     T
Sbjct: 145 VNQSSTAAWLYSN---FYGLAKVGINGLTQQLATELGGQNIRVNAIAPGPIDTEANRTTT 201

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             E  A+  +  +PL R G+PE++ G   FL SD A +ITG+   V GG
Sbjct: 202 PQEMVAD-IVKGIPLSRMGQPEDLVGMCLFLLSDQAKWITGQIFNVDGG 249


>UniRef50_Q5V3M2 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; Halobacteriaceae|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 247

 Score =  119 bits (287), Expect = 7e-26
 Identities = 75/227 (33%), Positives = 109/227 (48%), Gaps = 1/227 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRK-ESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           IAK LG+ GA+VV+  R  E+     V+ +R  G T       VA  +  R + E    +
Sbjct: 21  IAKDLGAHGANVVVNYRSSEAEARAVVEDIRERGGTAIAAQADVAKLDEVRAMREKVADE 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG  D+L               T +  W+ + DVN+   +   K  Y ++     G ++ 
Sbjct: 81  FGPADVLVNNAGITIDKKFENMTRDD-WETVIDVNLGGVFNGTKAFYDDIRDADHGRLIN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS+   Q       Y  +K+ L G T+ +A E  H     NCVAPG V T     +   
Sbjct: 140 ISSVVGQQGNIGQANYATTKSGLFGFTRTLALELAHTGSTANCVAPGFVKTDMLEEV--P 197

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E   EK L  +PL RF R E+IAG V F+AS+++SY+TG+ + V GG
Sbjct: 198 ERVQEKILREIPLDRFARVEDIAGIVRFVASEESSYMTGQVLGVNGG 244


>UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1;
           Zymomonas mobilis|Rep: Putative uncharacterized protein
           - Zymomonas mobilis
          Length = 254

 Score =  119 bits (286), Expect = 9e-26
 Identities = 70/221 (31%), Positives = 106/221 (47%), Gaps = 1/221 (0%)
 Frame = -3

Query: 733 ASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXX 554
           A V I  R E+N+ + ++ +   G     +   V+  +  +   E     FG +D     
Sbjct: 34  AYVAIIGRSENNIQETLRLVTEMGGQAIAIQADVSQEDSIKAAIEKTVETFGKLDFAFNN 93

Query: 553 XXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPT 374
                      D   + WD+I   N+   +   K   P ++K G GSIV  +S A  +  
Sbjct: 94  AGIEHKAIPAADIPSEEWDRIISTNLNGVFFSMKHEIPAMLKSGSGSIVNTASGAGVKGF 153

Query: 373 EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT-NSEAGAEKSLS 197
              GAY  SK  L+GL+KA A +   +++R+N VAPGI+ T      T  +E G E +++
Sbjct: 154 PGNGAYCASKFGLIGLSKAAALDYAKQHLRINVVAPGIIETPMMQRFTGGTEEGRETAIA 213

Query: 196 NVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
             P+ R G P+EIAG V +L SD A++ TG   VV GG  A
Sbjct: 214 QEPVGRAGHPKEIAGTVLWLCSDLAAFTTGSVFVVDGGQTA 254


>UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 258

 Score =  119 bits (286), Expect = 9e-26
 Identities = 66/229 (28%), Positives = 112/229 (48%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGA-SVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           A A R+ SEGA +++I  R+E+ +     + R  G     +   +   +   RL  +A  
Sbjct: 28  ATALRMASEGAEALIIAGRREAEIEATAAACREIGAAAIALKTDITREDDVARLVGIAVE 87

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           + G +D+             + +   +++D +FD NV++ +L  +   P ++ +G GSIV
Sbjct: 88  RCGRLDVAFNNAGFQERRAPLEEQGTEIYDSVFDTNVRALFLCLRHQLPAMLAQGRGSIV 147

Query: 406 FISSIAAYQ-PTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
             +S++  + P      Y  SK   + LT++ A E     IR+N +APG VVT     + 
Sbjct: 148 VNASVSGVRNPNPGFSLYSASKAAAISLTRSAAMENAPRGIRINAIAPGRVVTDM--MLR 205

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                     + +PL+R G PEE+A AV +L+SD ASY+ G  +   GG
Sbjct: 206 AGVGDVATVAAGLPLRRMGSPEEVAEAVVWLSSDAASYVVGHVLAADGG 254


>UniRef50_Q82QS5 Cluster: Putative dehydrogenase; n=1; Streptomyces
           avermitilis|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 267

 Score =  119 bits (286), Expect = 9e-26
 Identities = 76/230 (33%), Positives = 106/230 (46%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA     EGA V              + + SEG     VV    + +    +   A  +
Sbjct: 40  AIAVLAAREGADVACADVAAPAAAATAELVHSEGALSVAVVGDATDAKQSAAMVAEAVRR 99

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GG+D L               + E  WD++  +N+++ +L AK A P +    GG++VF
Sbjct: 100 LGGLDALVVNVGVGLGTGLDGSSPED-WDQVLSLNLRAPFLAAKHALPAMAD--GGAVVF 156

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I S+A  +      AY  SK  L GLT+ +A E     IR N V PG++ T      +  
Sbjct: 157 IGSVAGLRAATNSPAYDSSKAGLFGLTRHVAKEGGARRIRANLVVPGLIDTPMGRQASAQ 216

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            A    S   +PL R G   E+A AVAFL SD ASYITG+++VV GG  A
Sbjct: 217 RASRTASFERIPLGRQGTAWEVAEAVAFLLSDRASYITGQSLVVDGGLSA 266


>UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable
           3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
           sp. (strain RHA1)
          Length = 249

 Score =  119 bits (286), Expect = 9e-26
 Identities = 69/227 (30%), Positives = 107/227 (47%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+     GA V +    E    +  + LRS G  V    C +        L E   S+
Sbjct: 20  ATAELFAENGAKVAVADINEEGAAETAEILRSNGADVSVHTCDITEQPQTDALVEEVVSR 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D++              + D + W +I D+N+  S  L++ A   + ++  GSIV 
Sbjct: 80  FGRLDMMTSTVGWSDTTFFAQE-DAKYWRRIIDINLMGSIFLSRSAMGPMSEQKSGSIVL 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            SS A    T     Y  +K  ++G  K++A E   + +R+N ++PG   T    A ++ 
Sbjct: 139 TSSDAGKVGTMGETVYAGAKAGVIGFVKSLAREIARDGMRINAISPGPTDTPLLRAQSDQ 198

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               ++ +  VPLKR G   E A  + FLASD ASYITG+T+ V+GG
Sbjct: 199 HV-IDRMVKAVPLKRMGTASEQAAPIVFLASDYASYITGQTLSVSGG 244


>UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 254

 Score =  119 bits (286), Expect = 9e-26
 Identities = 74/228 (32%), Positives = 110/228 (48%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+   + GA+V+I   +          + ++G     +   V + E    +   A   
Sbjct: 24  AIAREFVARGAAVIITDVQREEGEAVAADILAQGGKALFIAHDVGDAEAWDVVVAKALDT 83

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG VD+L            + +   +++D++  VNV+  WL  K   P L   GGG+I+ 
Sbjct: 84  FGKVDVLVNNAGLIQFAP-LEEMPIEMFDRVTRVNVRGPWLGCKAILPALKAAGGGAIIN 142

Query: 403 ISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           +SS+       P L AY  SK  +  LTKA+A + V   +RVN V PG + + F +    
Sbjct: 143 MSSMNGMIAQNPGLSAYATSKGAVRMLTKAVAQDYVQYGVRVNSVHPGTIASTFVAPFLE 202

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                +K +   P+ R G P E+A  VAFLASDDASY+TG  V V GG
Sbjct: 203 DPNWRDKLVGRTPMARAGEPSEVAKVVAFLASDDASYMTGSEVAVDGG 250


>UniRef50_A6F000 Cluster: Putative short-chain
           dehydrogenase/reductase; n=1; Marinobacter algicola
           DG893|Rep: Putative short-chain dehydrogenase/reductase
           - Marinobacter algicola DG893
          Length = 255

 Score =  119 bits (286), Expect = 9e-26
 Identities = 78/234 (33%), Positives = 112/234 (47%), Gaps = 6/234 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+RL  EGASVVI          A + L  EG     V   V   +  + +  +A  K
Sbjct: 22  AYARRLAEEGASVVIAEIDVKAATSAAEELEKEGFEALAVHTDVTKPDSVKEMARLAAEK 81

Query: 583 FGGVDILXXXXXXXXXX----XSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
           FG +DIL                  + D + WD++  VNVK +WL +    P +  +  G
Sbjct: 82  FGRIDILVNNAAIFISVPMSRAPFDEIDPEEWDRMMAVNVKGAWLSSCAVAPYMRDQQYG 141

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF--A 242
            I+ ISS  A +  +    Y  SK  +LG TK +ANE   E + VNC+APG  +++    
Sbjct: 142 KIINISSGTALKGADNRIHYVASKAAILGFTKTLANELGKEGVCVNCIAPGSTMSEENPD 201

Query: 241 SAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
            AI    A A    S   + R   P ++ GAV F +S D+ +ITG+T+VV GG+
Sbjct: 202 DAIRQRRASA---ASTRAIPRLQMPGDMLGAVVFFSSSDSDFITGQTLVVDGGS 252


>UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2;
           Bacteroidetes|Rep: Short chain dehydrogenase -
           Algoriphagus sp. PR1
          Length = 252

 Score =  119 bits (286), Expect = 9e-26
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 4/235 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIAKR   EGA +++  R + N  +  +SL   G     V   V   E    L + A S 
Sbjct: 20  AIAKRFSEEGAFLILSGRNQENGIELERSLNEAGGKAVFVKGDVGIIETNEALVKAAISN 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DI+            + +     W +  + N  + + L++ A PE++K GGG+I+ 
Sbjct: 80  FGKLDIVVTNAGKLGLGS-VTEISLAEWQETMNTNFNAVFFLSRFAIPEMIKSGGGTILA 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF----ASA 236
            SSIAA++      AY  SK  L+ L K +A +    NIRVN + PG V T      A A
Sbjct: 139 NSSIAAFKSFPNHAAYCASKAALVALVKEMAVD-YGPNIRVNTMCPGPVDTPLIWDSAKA 197

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
             N +   +++  N  + R G+PE+IA    FL SD+AS+ITG    + GG  A+
Sbjct: 198 FDNPDTIVQETAKNTLMNRLGKPEDIASLALFLVSDEASWITGVAYPIDGGILAK 252


>UniRef50_Q9HLN6 Cluster: Probable glucose 1-dehydrogenase; n=4;
           cellular organisms|Rep: Probable glucose 1-dehydrogenase
           - Thermoplasma acidophilum
          Length = 268

 Score =  119 bits (286), Expect = 9e-26
 Identities = 73/228 (32%), Positives = 110/228 (48%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKA-VQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           AIAK +   GA V +  R   +   A V  ++++G         V+  E  ++LF    S
Sbjct: 30  AIAKYMARAGAKVAVHYRSGKDRADAIVDEIKNDGGFAMAFYGDVSKKEDVQKLFSEIDS 89

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           K G VDIL            + + D   W+K+ +VN+   +  A+EA   +  +  G I+
Sbjct: 90  KLGTVDILVNNAGIDGKRELVGEDDPDDWEKVIEVNLMGPYYCAREAVKRMKPKKSGVII 149

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            I+S+  Y P     AY  +K  L   TKA+A E    NIRV  +APG + T     +  
Sbjct: 150 NITSVHEYVPWSGYTAYSSAKAGLSMFTKALAQELSDYNIRVVAIAPGAIKTPINKDVWG 209

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +    +  L+ + + R G  ++I  A  FLASD ASYITG T++V GG
Sbjct: 210 NPESLKDLLNKIAMPRLGEVDDIGQAAVFLASDLASYITGTTLLVDGG 257


>UniRef50_Q930I9 Cluster: Putative; n=6; Alphaproteobacteria|Rep:
           Putative - Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 226

 Score =  118 bits (285), Expect = 1e-25
 Identities = 69/222 (31%), Positives = 102/222 (45%)
 Frame = -3

Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
           +   GA V + +R    + +    +   G     +   V + E    +   A    GG+D
Sbjct: 1   MAEAGAHVAVTARTVEGLAETRALIEKTGRRAVALAQDVRDVEACASVTRAAAEGLGGLD 60

Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIA 389
           IL           S  D DE +WD I   N+K ++  A+ A   +    GG+IV + S+ 
Sbjct: 61  ILVNNAGFENVRPSF-DVDEALWDTIVSTNLKGAFFCAQAAGRIMADANGGAIVNLCSLT 119

Query: 388 AYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAE 209
           +Y        YG SK+ LLG+T+A+A E    NIRVN +APG   T   +     E    
Sbjct: 120 SYVGIPTAVPYGASKSGLLGVTRALATEWAAHNIRVNAIAPGYFRTAMTAGFYEDEDWQS 179

Query: 208 KSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           + L  +P +RFG+  +I G   FL SD A+YITG  +   GG
Sbjct: 180 RMLEKIPQRRFGKESDIGGVAVFLCSDAAAYITGHCIPADGG 221


>UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Mycobacterium sp. (strain MCS)
          Length = 266

 Score =  118 bits (285), Expect = 1e-25
 Identities = 76/230 (33%), Positives = 112/230 (48%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A     EGA +V+   +   +      LR  G  VE VV  V+      R+   A  +
Sbjct: 34  ATAVLFAREGARLVVTDIQSEPLLALADELRHAGADVEPVVGDVSVEYDAGRMIGAAVDR 93

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D+L           + L+     WD++  ++ +  +L  K A   ++  GGG+IV 
Sbjct: 94  FGRLDVLVANAGIIPLGDA-LEMTAAGWDEVMAIDGRGMFLCCKFAIEAMLPTGGGAIVC 152

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SSI+     +   AYG +K    GLTK +A E     IRVN VAPG + T+        
Sbjct: 153 LSSISGLAGQKRQAAYGPAKFIATGLTKHLAVEWADRGIRVNAVAPGTIRTERVKRFPEE 212

Query: 223 EAGAE--KSLSNV-PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             G+E   ++  + P+ R G P E+A A+ FLASDDAS+ITG  + V GG
Sbjct: 213 PGGSEYLAAVERMHPMGRIGEPAEVASAIVFLASDDASFITGAVLPVDGG 262


>UniRef50_Q15TE7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=8; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Pseudoalteromonas atlantica (strain T6c /
           BAA-1087)
          Length = 266

 Score =  118 bits (285), Expect = 1e-25
 Identities = 75/234 (32%), Positives = 117/234 (50%), Gaps = 6/234 (2%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A+ +G+ G ++++    +  +    +SLR EGI V       +  +    + E A S +G
Sbjct: 33  ARVIGNSGCNLLLTGGNKEALESLAESLRQEGIHVATRNTRPSTEQECDAMVEQAVSTYG 92

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
            +DIL            I D   + W K+ D NV+ SWLL K A  + + +GGG  V + 
Sbjct: 93  KLDILVVGSGVNDVDP-IQDLSTERWQKVMDANVRDSWLLCKAAGKQFMSQGGGGKVVLV 151

Query: 397 SIAAYQPTEPLG--AYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS-AITN 227
           S A  +   P G  AY  SK+ + GLT+A+  E    NI VN +AP +  +   +    +
Sbjct: 152 SSARGKLGHPAGYSAYCPSKSAVDGLTRALGCEWGKHNITVNAIAPTVFRSNLTAWMFED 211

Query: 226 SEAGA---EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           +E G    E  L+ +P+ R G PE++AG + FLASD +S+ TG  +   GG  A
Sbjct: 212 NEPGKSTRENILARIPMGRLGEPEDLAGPLLFLASDASSFHTGHVIYADGGYSA 265


>UniRef50_A5VAV2 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Sphingomonas wittichii RW1|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Sphingomonas wittichii RW1
          Length = 253

 Score =  118 bits (285), Expect = 1e-25
 Identities = 79/237 (33%), Positives = 115/237 (48%), Gaps = 7/237 (2%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A  L   GA V++C   +     AV  LR EG+  +G+V  VA+      +      +F
Sbjct: 22  LAADLARRGAKVMLCDVADPMA--AVARLRDEGLDADGMVADVADPSAFAGVVAGCVDRF 79

Query: 580 GGVDILXXXXXXXXXXXSI----LDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
           G +DIL                 LD DE  W ++ DVNV   +L ++ A P+L   GGG 
Sbjct: 80  GRLDILVNNAGLFTTIGRAPFEELDVDE--WRRVLDVNVTGPFLCSRAALPQLRAAGGGR 137

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA--- 242
           I+ I S   +     +  Y  SK  L  +T+++A E   + I VN +APG  ++      
Sbjct: 138 IINIGSATVFSAPPNMLHYVASKGALTAMTRSMAREVGKDGITVNLIAPGFTISAGVLEH 197

Query: 241 SAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
            A T  E GA    +   + R   P++I GAV+FLA DDA +ITG+T+VV GG   R
Sbjct: 198 QAATLGEHGARMRAARA-IGRDQMPQDICGAVSFLAGDDAGFITGQTLVVDGGIVMR 253


>UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Roseiflexus|Rep: Short-chain
           dehydrogenase/reductase SDR - Roseiflexus sp. RS-1
          Length = 248

 Score =  118 bits (285), Expect = 1e-25
 Identities = 72/228 (31%), Positives = 115/228 (50%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A   G  GA VVI +R  S   + V ++R+ G T   V   V      R L +   + 
Sbjct: 19  ATALAFGRHGARVVIGNRNASTGEETVAAIRATGGTALFVPTDVTQPVAVRALIDTTVAT 78

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV- 407
           FG +DI             + D DE+ +D +FD NV+ ++L  K    +++K+G G I+ 
Sbjct: 79  FGRLDIAFNNAGWFGPVAPLADQDEREFDPVFDTNVRGTFLCMKYELAQMLKQGQGIIIN 138

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
             S+  A   T  +  Y  +K  ++ LT++ A E   + +R+N VAPG + T   +    
Sbjct: 139 NASTTGARNSTVGVALYAAAKAAVISLTRSAAMEYAAQGVRINAVAPGRIATGMLAKA-- 196

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                E+  + +P++R G PEE+A AV +LAS  AS++TG+ + V GG
Sbjct: 197 GGGNPERFAAVIPMRRLGTPEEVAEAVLWLASPAASFVTGQVLGVDGG 244


>UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Methylobacterium
           sp. 4-46
          Length = 275

 Score =  118 bits (285), Expect = 1e-25
 Identities = 73/227 (32%), Positives = 113/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A+    EGA++VI     +    A   L   G     V   VA+      + E   ++
Sbjct: 22  AVARAFAREGAALVIADVNRAGAEAAAAGLAEAGGRAMAVAVDVADPASIAAMVEAILAR 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +DIL             L+T  + W++I  +N+  ++L+A+    E+V+ GGG IV 
Sbjct: 82  HGRLDILVNNAGVGGNTP-FLETRLEDWNRIIGINLTGAFLVAQACAREMVRGGGGKIVN 140

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I+S++  +  +   AYG +K  L  LTK +A E     I VN +APG + T+ A    ++
Sbjct: 141 IASLSGQRGGDGRAAYGAAKAGLELLTKVMAVELSEHGINVNNIAPGAIETEMARFAHDA 200

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              A      +P+ R+G PEEIA A  FL SD+A Y+ G T+ V GG
Sbjct: 201 ATRAAYGYL-IPMTRYGTPEEIADAAVFLCSDEARYVQGHTLNVDGG 246


>UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;
           cellular organisms|Rep: Contig An08c0220, complete
           genome - Aspergillus niger
          Length = 253

 Score =  118 bits (285), Expect = 1e-25
 Identities = 79/222 (35%), Positives = 113/222 (50%), Gaps = 3/222 (1%)
 Frame = -3

Query: 739 EGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILX 560
           EGA+VVI    + N GK VQ  + +G  V  V   V++     R+ EVA   F  +DI+ 
Sbjct: 31  EGANVVIVDLDQEN-GKRVQCAQPKGRAVF-VQGDVSSESDWERVREVALENFKKIDIVV 88

Query: 559 XXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQ 380
                       L+T E + D+++ VNVKS +  AK   P    +GGG  V ISS+++ +
Sbjct: 89  NNAGIVHVVQPSLETSETMLDRMYKVNVKSIYHSAKTIAPYFQAQGGGVFVNISSMSSIR 148

Query: 379 PTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKS- 203
           P      Y  +K  +   TK++A E  + +IR+N V P    T     I   E   E   
Sbjct: 149 PRPKYAWYSATKGAVSAATKSLAAEFANNHIRLNTVCPVAGETGMMPLILGGEDTPENRS 208

Query: 202 --LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             LS +P+ RF  P ++A A AFLASD+AS+ITG  + V GG
Sbjct: 209 IVLSTIPMGRFATPADVANATAFLASDEASFITGVELAVDGG 250


>UniRef50_Q7NFL8 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=36; Bacteria|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Gloeobacter violaceus
          Length = 248

 Score =  118 bits (284), Expect = 2e-25
 Identities = 77/229 (33%), Positives = 115/229 (50%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVI-CSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           A A  L SEGA+V +  SR E    + V ++ + G     +   VA+ E   RLF    +
Sbjct: 22  ACALALASEGAAVAVNYSRSEEAAQQVVAAIEAAGGQAVALKADVADPEQVERLFADLLA 81

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           K+G +D L            IL    + W+ +  +N+  ++L  K A   ++K+  G +V
Sbjct: 82  KYGRLDALVNNAGITRDGL-ILRMSLEDWNDVVSLNLTGTFLCLKAASRIMLKQRSGRVV 140

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ISS +          Y  +K  +LGLT++ A E     I VN VAPG + T   SA+  
Sbjct: 141 NISSTSGVAGNAGQANYSAAKAGVLGLTRSAARELGSRGITVNAVAPGFIATDMTSALE- 199

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDD-ASYITGETVVVAGG 83
                E  L+ VPL+R G+PEE+AG V FL +D  A+YITG+ + + GG
Sbjct: 200 ----LEPILAQVPLRRVGQPEEVAGLVRFLCADPAAAYITGQVITIDGG 244


>UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Sphingomonadaceae|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 266

 Score =  118 bits (284), Expect = 2e-25
 Identities = 73/238 (30%), Positives = 115/238 (48%), Gaps = 8/238 (3%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A  +  +G  VV+     S   + V+++R+E      + C++      + L +     
Sbjct: 22  ASAMEMARQGGRVVVTDINTSAGEETVEAIRAEKGDAIFIACNLRKAHEIKVLMQKTADH 81

Query: 583 FGGVDILXXXXXXXXXX----XSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
           FGG+D+L               SI D  E++WD +++VN+K+ WL  + A P L    G 
Sbjct: 82  FGGIDVLHNNAAIHETDLTDKTSIEDLPEEIWDAVYEVNLKALWLTTRYAVPWLKLSKGA 141

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----K 248
           +IV ++S  ++      GAY  +K  +L LTKA A +     IR NC  PG + T    K
Sbjct: 142 AIVNVASTGSFVSYPQAGAYCATKGGVLLLTKATAVDLAKYGIRCNCYCPGAIETPMLQK 201

Query: 247 FASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           +  A  + +A          + R G+PEE+A    FLASDD+S+I G + V+ GG  A
Sbjct: 202 YLDAAEDKKAIMSVLTGAHLIPRLGKPEEVAKLACFLASDDSSFINGASYVIDGGTLA 259


>UniRef50_Q1YNT8 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1; gamma
           proteobacterium HTCC2207|Rep: Oxidoreductase, short
           chain dehydrogenase/reductase family protein - gamma
           proteobacterium HTCC2207
          Length = 256

 Score =  118 bits (284), Expect = 2e-25
 Identities = 73/232 (31%), Positives = 119/232 (51%), Gaps = 1/232 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A+     G +V+  +R+   + + V  + ++G     V   V + +  +  F+ A ++ 
Sbjct: 26  MAEMFADNGVAVICAARRTDRLQQVVDRITAKGGRAIVVTMDVTDRDSVKAGFDAAEAQL 85

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG-GSIVF 404
           G  DI+             L+ +E VWD + +VN+K  + L +EA   +V  G  GSI+ 
Sbjct: 86  GTPDIVVCNAGATGAQP-FLEMEEAVWDNVLNVNLKGVFNLGQEAAQRMVAAGKPGSIIN 144

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISSI A    + L  Y  SK  L  LT  + +E    +IRVN +APG ++T   S    +
Sbjct: 145 ISSICAVASFKGLTHYSSSKAALNQLTAVMGHELAEHSIRVNALAPGYMMTDMVSDYYAT 204

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
           EAG ++ L+ +PLKR G  +E+ GA+  LASD +SY++G  + V      RL
Sbjct: 205 EAG-QRDLATLPLKRAGELKELDGALLLLASDASSYMSGSVITVDAAHSIRL 255


>UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Acidobacteria bacterium (strain Ellin345)
          Length = 271

 Score =  118 bits (284), Expect = 2e-25
 Identities = 70/231 (30%), Positives = 120/231 (51%), Gaps = 4/231 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+++   GASV I    E    K   ++R+ G   +   C V+  +   +      +K
Sbjct: 22  ACARKIALAGASVAILDPNEDAGTKTAAAIRAHGGECKFFRCDVSKSKDVEQAVGDVITK 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
              +DIL            ++ T E  WD++  VN+K  +L++K   P ++  GG +IV 
Sbjct: 82  HSQIDILVSNAGIQYYGD-VITTPEDDWDRVIGVNLKGCFLISKFCVPHMISNGG-AIVV 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT---KFASAI 233
           + S+ ++   +   AY  SK  +LGL +A+A +  H+ IRVNCV PG + T    +A+++
Sbjct: 140 LGSVQSFTAIQNSAAYVTSKHAVLGLARAMALDYAHKGIRVNCVCPGTIDTPMLHWAASL 199

Query: 232 TNSEAGAEKSLSNV-PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +       ++   +  L R G+P+E+A AV +LAS  +S+ITG  ++V GG
Sbjct: 200 SPDPESVIRTCDRMHALGRIGKPDEVADAVLYLASPMSSFITGAALLVDGG 250


>UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 263

 Score =  118 bits (284), Expect = 2e-25
 Identities = 73/227 (32%), Positives = 116/227 (51%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A R   EGA VV+     S    A   ++++      V   V++ E    +F+    +
Sbjct: 24  AVALRFADEGALVVLNDLDASRAEDAASEVKAD----LWVAADVSDKEQVDAMFDRVEEE 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D+L             L+ DEQ WD++  VN+K ++L +  A  ++V++  G I+ 
Sbjct: 80  YGRIDVLVNNAGNIYAARHFLEGDEQWWDQVLGVNLKGAFLCSHRAAQKMVRQRSGVILN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS  A +      AY  SK  +  +T+A+A +     +RVN + PG++ T   S  T +
Sbjct: 140 MSSGGATRAHRGNVAYDASKGGIEAMTRAMALDLAPYGVRVNAIVPGLIRTYDISDETAA 199

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E G       VP+ R G PE++AG   FLA+DDA YITG  +VV GG
Sbjct: 200 ERG-----EVVPMGRLGTPEDLAGPTVFLATDDARYITGACLVVDGG 241


>UniRef50_A3Z051 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Synechococcus sp. WH 5701|Rep: Short-chain
           dehydrogenase/reductase SDR - Synechococcus sp. WH 5701
          Length = 256

 Score =  118 bits (284), Expect = 2e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+R    GA + +  R    +G+    + +       +   V++ E  RR  + A + 
Sbjct: 23  AIAERFSEAGADIGVIGRDREGLGRIQGIVENNHRNCWVIEEDVSSIEGARRAGDKALAL 82

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
               D+L            IL+T +  W+ IF VN++S+ LL++   P+++KRG G +V 
Sbjct: 83  DPEWDVLVNNAGIARVQS-ILETTQDNWNDIFSVNLRSALLLSQAIVPQMIKRGHGKVVN 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISSI A+  T  LGAY  SK  L  LT+ +A E    N++VN + P +++T+    I +S
Sbjct: 142 ISSIGAFIGTPGLGAYAASKAALNQLTRTMAVEWGPHNVQVNALCPTVILTQMGHDIWDS 201

Query: 223 ---EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              E   ++    +PL RFG P E+A    FLAS  ++++ G ++ + GG
Sbjct: 202 PSMEEPRKEKEKRIPLHRFGEPTEVANVALFLASPASNFVHGVSLPLDGG 251


>UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine
           gamma proteobacterium HTCC2080|Rep: Short chain
           dehydrogenase - marine gamma proteobacterium HTCC2080
          Length = 251

 Score =  118 bits (284), Expect = 2e-25
 Identities = 67/227 (29%), Positives = 109/227 (48%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A RL   G +V +     +   +A   L S+G     +V  V+  +   +LF++    
Sbjct: 22  ACAARLAEAGVAVGVADIDSAAAHQAAADLTSQGHRCVAIVTDVSKAKEVEKLFQITNEA 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG ++I             + DT+E+ +D++  VN+K  WL  + A   +  +  GSI+ 
Sbjct: 82  FGPINIAVNNAGVGAPLTPLGDTEEEDFDRVMAVNLKGVWLCMRAALRHMAPQKSGSIIN 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S  +       G Y  SK  + GLT++ A E     IR+N + PG + T    +    
Sbjct: 142 MASALSTTTFPGSGLYTASKHGVAGLTRSAAVEYGESGIRINAICPGFISTPLLHSTVTE 201

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           EA A+   +  P+ R G P EIA AV +LASD +S++TG    + GG
Sbjct: 202 EA-AKSMAARHPMNRLGTPAEIADAVTYLASDASSFVTGSLFSIDGG 247


>UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine
           gamma proteobacterium HTCC2143|Rep: Short chain
           dehydrogenase - marine gamma proteobacterium HTCC2143
          Length = 264

 Score =  118 bits (284), Expect = 2e-25
 Identities = 74/213 (34%), Positives = 108/213 (50%), Gaps = 7/213 (3%)
 Frame = -3

Query: 688 AVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDE 509
           A+  L    IT+EG    V   +  +R  +  T +FGG+DIL            +   DE
Sbjct: 55  AMTDLSGSIITIEG---DVTQADDWQRAVDTITGEFGGLDILVNNAGIIEAGSRLEKFDE 111

Query: 508 QVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLG 329
            V+D++  VN K ++L  K   P + KR GG+IV +SSI+ +  +    AY  SK  +LG
Sbjct: 112 NVFDRVMAVNTKGTFLGMKAVIPAMRKRHGGAIVNVSSISGHCGSAVATAYTASKHAVLG 171

Query: 328 LTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL-------SNVPLKRFGR 170
           +TK+ A +    +IRVN V P  + T     +   +   + S        S  PLKR G 
Sbjct: 172 MTKSAALDLAEYDIRVNAVCPAPIDTPMVRNLGTRQQAKDPSFDIAAVMSSGTPLKRLGD 231

Query: 169 PEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           P E+A A+ FLAS+ AS+ITG  + V GG  A+
Sbjct: 232 PGEVASAILFLASEQASFITGAGLPVDGGVLAK 264


>UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=1;
           Natronomonas pharaonis DSM 2160|Rep: Probable
           dehydrogenase/ reductase 4 - Natronomonas pharaonis
           (strain DSM 2160 / ATCC 35678)
          Length = 253

 Score =  118 bits (284), Expect = 2e-25
 Identities = 70/231 (30%), Positives = 113/231 (48%), Gaps = 4/231 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A ++  EGA VV     E    + V ++   G         V + +  + + E A  +
Sbjct: 20  ATALKVAREGAFVVATDINEDGGRETVDAVEDAGGDAAFHELDVTDADEFKAVVETAADE 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D +              D  E  ++ + DVN++  W   + A P L  +G G+IV 
Sbjct: 80  YG-LDAMINNAGVGHPPAYTEDVTETTFEYVLDVNLRGVWNGCQAALPHLKSQGEGAIVN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           + S+A++        Y ++K  +L LT+AIA+E   + +R N V PG + T        S
Sbjct: 139 VGSLASFLGLPKQAVYSLTKGAVLNLTRAIASEAGRDGVRANAVCPGFIETPLGDQFFQS 198

Query: 223 EAGAEKSLSNV----PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +   EK+ +      PL R G PEE+A A+AFLASD+AS+++G  +VV GG
Sbjct: 199 KRDPEKAKAETEKQYPLGRLGEPEEVADAIAFLASDEASFVSGHGLVVDGG 249


>UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1;
           Mesorhizobium loti|Rep: Probable short-chain
           dehydrogenase - Rhizobium loti (Mesorhizobium loti)
          Length = 261

 Score =  118 bits (283), Expect = 2e-25
 Identities = 74/238 (31%), Positives = 115/238 (48%), Gaps = 8/238 (3%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+RL   GA+++ C    +      +SL   G         V+  +  R       +K
Sbjct: 20  ATARRLAQGGAAIIACGIDRAANAAMQESLAKAGADALVQTVDVSISDQVRDAVVAGVAK 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+D++           +   TD + W++   VNV S +L A    PE++KRGGG+IV 
Sbjct: 80  FGGIDVIVNSAAVHPYGTATT-TDWETWNRAMSVNVGSIYLTAHFGIPEMIKRGGGAIVN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASA 236
           ++S+  +   + + AY  +K  +  LT+++A +     IRVN V+PG + T    K A  
Sbjct: 139 VASVQGFACQQNVAAYATTKGAIHTLTRSLALDYAAAGIRVNSVSPGSIRTPILEKAARG 198

Query: 235 ITNSEAGAEKSLSNV----PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
              S+A  E++        PL R G PEE+A  +AFL S  AS+ TG    + GG  A
Sbjct: 199 DHGSDADVEEAYKRFGAAHPLGRIGEPEEVAEFIAFLCSSKASFCTGADYKIDGGLTA 256


>UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein;
           n=2; Streptomyces|Rep: Ketoacyl ACP/CoA reductase-like
           protein - Streptomyces natalensis
          Length = 257

 Score =  118 bits (283), Expect = 2e-25
 Identities = 78/230 (33%), Positives = 111/230 (48%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+    EGA+VV+ +R+   +   V  +R  G     +   V+  E  RR  E    K
Sbjct: 25  ATARLFAREGAAVVLAARRVDRLRALVSEIRRTGAEAAYIATDVSQEEDVRRAVEFTVEK 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIV 407
           +G +D+            S+    +  +D +   NV+  W   +     ++  G GGSIV
Sbjct: 85  YGRLDLAFNNAGVGCDHESMHLMQQDTYDDVMGTNVRGVWHCLQHEISAMLHNGVGGSIV 144

Query: 406 FISSIAAYQPTEPLGA-YGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
             SS+A  Q   P GA Y  SK  ++GLTKA A E   + IRVN VAPG   T+  +   
Sbjct: 145 NNSSVAGLQAI-PAGAPYIASKHAVIGLTKAAAAEYAPQGIRVNSVAPGTTRTEIIAGWF 203

Query: 229 NSEAGAEKSLSN-VPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +   G E+ L    P  R   PEEIA AVA+L SD +S++TG  + V GG
Sbjct: 204 DRNPGLEEQLHRATPQARTAEPEEIAQAVAWLCSDRSSFVTGAVLPVDGG 253


>UniRef50_A7HFH2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Anaeromyxobacter sp. Fw109-5|Rep: Short-chain
           dehydrogenase/reductase SDR - Anaeromyxobacter sp.
           Fw109-5
          Length = 276

 Score =  118 bits (283), Expect = 2e-25
 Identities = 73/232 (31%), Positives = 116/232 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+   + GA+V + +R  + +   V+S+R+EG     +   V +      L    T  
Sbjct: 29  ATARAFAAAGAAVALAARDGAALNGVVESIRAEGGDAMAIPTDVGDAGAVAHLVAETTRV 88

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D              + D D   +D+    +V+ ++L  K   P +++ GGG+IV 
Sbjct: 89  FGRLDAAFNNATDGPPPAPLADLDPDDFDRGIRADVRGTFLGMKYEIPAMLRSGGGAIVN 148

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S+AA      LGAY   K+ ++GLT+  A +     IRVN VAPG ++T         
Sbjct: 149 MASLAALYGFTGLGAYVAGKSGIIGLTRVAALDYADRGIRVNVVAPGPILTHHLERA--G 206

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
           E    ++ S  P+ R GR EE+A AV +L S+ AS+ITG T+ + GG  A L
Sbjct: 207 EEAQRQAASATPMGRIGRVEEVAAAVLWLCSEQASFITGVTLPIDGGQSAGL 258


>UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
          Length = 260

 Score =  118 bits (283), Expect = 2e-25
 Identities = 70/229 (30%), Positives = 110/229 (48%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK L S GA ++I    E       Q   +   T+  +   V        LF  A  +
Sbjct: 29  ASAKLLASRGAKIIIADLAEDLGHALAQQAWASDHTINFMKVDVTQAAEVNALFAYAVEQ 88

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GG+D++            +    E  +D+   VNVK  W   + A   L   GGG ++ 
Sbjct: 89  LGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCMRAAIACLSPHGGGHVIN 148

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAITN 227
           ++SIA  +    L AY  SK  ++GLTK+ A E    NIR N V P  + T    +++ N
Sbjct: 149 VASIAGLRSAPMLSAYSASKHAVIGLTKSAAIEYARANIRFNAVCPSFIDTPMVRNSMLN 208

Query: 226 SEAGAEKSLSNV-PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                + +L N  P++R G+ EE+A A+A+LASD++S++ G ++ + GG
Sbjct: 209 MNEKQQHALLNASPMRRLGKVEEVASAIAWLASDESSFMNGHSLTLDGG 257


>UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2;
           Actinomycetales|Rep: L-xylulose reductase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 262

 Score =  118 bits (283), Expect = 2e-25
 Identities = 76/228 (33%), Positives = 114/228 (50%), Gaps = 2/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSK 584
           IA+   + GA +V+  R  S +  A ++L  + G  V  V   +A  +    L   A   
Sbjct: 32  IARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVAIDLAEPDAPAELARRAAEA 91

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIV 407
           FGG+D+L            ++DTD Q++D    VN+++  LLA      +V  G GG+I+
Sbjct: 92  FGGLDVLVNNAGISHPQP-VVDTDPQLFDATIAVNLRAPALLASAVGKAMVAAGEGGAII 150

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ++S AA  P     AY  SK  L+  TK +A E     IR N V P +V+T+    +  
Sbjct: 151 TVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSVCPTVVLTEMGQRVWG 210

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            EA +   ++ +PL RF  P E++ AV +LASD AS I G  + V GG
Sbjct: 211 DEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVDIPVDGG 258


>UniRef50_Q3IRP1 Cluster: Probable dehydrogenase/ reductase 11; n=1;
           Natronomonas pharaonis DSM 2160|Rep: Probable
           dehydrogenase/ reductase 11 - Natronomonas pharaonis
           (strain DSM 2160 / ATCC 35678)
          Length = 258

 Score =  118 bits (283), Expect = 2e-25
 Identities = 63/226 (27%), Positives = 109/226 (48%), Gaps = 4/226 (1%)
 Frame = -3

Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
           L +EGA VV            V+ + ++G T   V C + +            ++ GG+D
Sbjct: 27  LAAEGAEVVALDVNLGAAENVVEEIEADGGTAHAVECDLTDRADVEDTIAALEAETGGID 86

Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIA 389
           +L            I + D+++WD+   VN+  ++ + +  YP + +RG G I+ +SS+A
Sbjct: 87  VLVNNAGMVDARDRIEEFDDEIWDRDISVNLTGAYNVTRAVYPNMKERGWGRIINMSSMA 146

Query: 388 AYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAE 209
            +Q      +Y  +K  L+G  K +A E     +  N +AP IVV + A    +     +
Sbjct: 147 GWQGGFGQASYAATKAALIGFGKTLALEGAQHGVTSNIIAPSIVVGQLADLPIDQLETVD 206

Query: 208 KSLSNV----PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +  + +    P++R G   ++A  VA+LAS+ A YITG+ V V GG
Sbjct: 207 EHFARIAKATPMRRLGTEADVANLVAYLASEQADYITGQVVGVTGG 252


>UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii
           KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
           KSM-K16)
          Length = 257

 Score =  117 bits (282), Expect = 3e-25
 Identities = 69/228 (30%), Positives = 111/228 (48%), Gaps = 2/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSK 584
           IAK L + G  + I         KA Q + +   +  + +   V+  E    + +     
Sbjct: 27  IAKSLAAFGCDIAIVDIDAEAAAKAAQEITTTYSVNTQSIQADVSKEEEVSAMVDRVLES 86

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           F  +D+L           + LD     W +  DVN+ + +L +K+    +V  G GSI+ 
Sbjct: 87  FPQIDVLVNNAGIVKKIDT-LDMTYSDWKRTMDVNINALFLTSKQVGKHMVANGSGSIMN 145

Query: 403 ISSIAAYQPT-EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           +SS++A     E   AY  SK  +  LTK++A+E     IRVN +APG + ++    +  
Sbjct: 146 MSSMSAMIANREAQSAYNASKGAVSMLTKSLASEWAQYGIRVNAIAPGYMASQMTGPLFA 205

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                E  L +VP+KR GRP+E++G   +LASD +S+ TG  +VV GG
Sbjct: 206 PGGELEHILEHVPMKRLGRPDELSGIAVYLASDASSFTTGSIIVVDGG 253


>UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=3; Cyanobacteria|Rep: NAD-dependent
           epimerase/dehydratase precursor - Anabaena variabilis
           (strain ATCC 29413 / PCC 7937)
          Length = 251

 Score =  117 bits (282), Expect = 3e-25
 Identities = 75/232 (32%), Positives = 115/232 (49%), Gaps = 1/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A     + A VV+  R+     + V+ ++  G     V   V      + + + A   
Sbjct: 20  ATAIAYAKQQAKVVVVGRRIDEGEETVRLIQEAGGEAFFVQSDVTKEADVKAMVDKAVGV 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DI            S+++  E  +D+I +VNVK  WL  K    +++K+G G+IV 
Sbjct: 80  FGRLDIAFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGVWLSMKYEIAQMLKQGSGAIVN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            SS A       +  Y  SK  ++GLTKA A +     IR+N VAPG + T    A T  
Sbjct: 140 TSSGAGVVALPGVPLYTASKHAVVGLTKAAALQYAKAGIRINAVAPGSIETDMFEAATGG 199

Query: 223 EAGAEKSLSNV-PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           +   +  ++ + P+ R G P E+A AV FL+SD AS+ITGE ++V GG  A+
Sbjct: 200 QDEVKAYITGLHPIGRIGTPLEVANAVLFLSSDIASFITGEMLMVDGGFVAQ 251


>UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 262

 Score =  117 bits (282), Expect = 3e-25
 Identities = 78/230 (33%), Positives = 112/230 (48%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA R  +EGASVV  S      G+AV      G    GV   V++    RR+   A   
Sbjct: 20  AIAHRFAAEGASVVCASVS----GRAVDVAAEIGDGALGVKADVSDEADVRRMIGAAEEA 75

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL            I +   + WD++  VN++  +   K     + + GGGS+V 
Sbjct: 76  FGRIDILVNNAGFGGKLKPIHEQSTEDWDRVHGVNLRGVFFCMKYGIMSMRRTGGGSVVN 135

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT---KFASAI 233
           +SS  A    +  G YG +K  +  LT+  A +   +NIRVN V PG + T   + +   
Sbjct: 136 VSSTTAVIGWKHHGIYGAAKAGVNQLTRVAALDYADDNIRVNAVCPGTIWTGLVQLSKEH 195

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                G  + L  +P+ R+G  +EIA A  FLASD+ASY+TG  + V GG
Sbjct: 196 PEPPPGVFR-LPGIPMDRWGLSDEIAAATLFLASDEASYVTGVLMPVDGG 244


>UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 250

 Score =  117 bits (282), Expect = 3e-25
 Identities = 70/226 (30%), Positives = 110/226 (48%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           I   L + GA+V           +  + +   G     V   V++     R+ E    + 
Sbjct: 22  ICAGLAAAGAAVAAVDVDLEKARRVERLVAGRGGRCVAVEADVSSRRSVERMAERVAGEL 81

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           GG+DIL              + DE+ WD++  VN+K  +L A+ AYP + +RGGG I+ +
Sbjct: 82  GGIDILVNNAAIYPLRPWT-EIDEEEWDRVLAVNIKGYFLCARAAYPYMRERGGGRIINV 140

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +SI  +        Y  SK  ++G T+ +A E   E I VN V+PG   T       + E
Sbjct: 141 ASITFFIGWAGFLDYVSSKGAVVGFTRTLAREVGPEGITVNAVSPGAFPTDAERVHPDQE 200

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           A   + L    +KR G+PE++   V FLAS++AS+ITG+T+ + GG
Sbjct: 201 ALNRRILDAQCIKRRGKPEDVGNLVTFLASEEASFITGQTIEIDGG 246


>UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 259

 Score =  117 bits (282), Expect = 3e-25
 Identities = 78/235 (33%), Positives = 117/235 (49%), Gaps = 3/235 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVIC---SRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVA 593
           AIA  L   GA V +    +  +  VG+  ++ R     V G +  V   E   R+ E A
Sbjct: 21  AIAVELARCGADVAVHYAHTPPDETVGEVERAGR-RAHPVRGDLSRVPECE---RVVEEA 76

Query: 592 TSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
               GG+D+L             LDTDE+ +D IFD+N+K  +  A+ A P +++ GGGS
Sbjct: 77  AEALGGLDVLVNNAGITRALD-FLDTDEETYDAIFDLNMKGYFFCARSAVPHMLEAGGGS 135

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           IV I+S+  +       AY  +K  ++  T+ +A E     IRVN + PG++       I
Sbjct: 136 IVNITSVHGFAGFPHHTAYAATKGAIIAFTRQLAIELAGRGIRVNAIGPGLIEVPRYYDI 195

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
                  E+    VP  R G+P+++  A AFLASD A +ITG+ + V GG  AR+
Sbjct: 196 PG--YSPEQGRELVPWGRVGKPKDVGPAAAFLASDAADFITGQVLYVDGGTTARM 248


>UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain
           dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep:
           Putative oxidoreductase; short-chain
           dehydrogenase/reductase - Frankia alni (strain ACN14a)
          Length = 297

 Score =  117 bits (282), Expect = 3e-25
 Identities = 77/230 (33%), Positives = 120/230 (52%), Gaps = 3/230 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IA+    EGA+VV+ +R      + V+  R  G++   V+  +A       +F+ A ++ 
Sbjct: 54  IAEAFAVEGATVVVAARTARYGERTVREFRERGLSASLVIGDLAERADVATMFDEAVARH 113

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVF 404
           G +D++            + + D+   D +   NV +   + + A P L + +  G ++F
Sbjct: 114 GALDVVVHSAADNAQGL-LAEIDDDTLDYLLRSNVHALHWITRAAVPHLTRSKLPGRMIF 172

Query: 403 ISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT-KFASAIT 230
           ISS AA +   P L AYG +K  L    + +A E     +RVN V PG+ VT +    +T
Sbjct: 173 ISSGAANRVFSPGLNAYGSTKAYLESFARGLAGELGPLGVRVNVVGPGLTVTERMLGHLT 232

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           +++A A    S  PL R G PEEIA AV FLAS +ASYITG +++V GGA
Sbjct: 233 HAQADA--LASTYPLGRAGLPEEIAAAVLFLASREASYITGASLLVDGGA 280


>UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Congregibacter litoralis KT71|Rep: Short-chain
           dehydrogenase/reductase SDR - Congregibacter litoralis
           KT71
          Length = 259

 Score =  117 bits (282), Expect = 3e-25
 Identities = 78/235 (33%), Positives = 113/235 (48%), Gaps = 4/235 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+++ + GAS+V+     S V      L  EG     +   V       R   +A   
Sbjct: 25  ASARKMAAAGASLVLTDINHSAVAALADELGREGTQAAALQHDVTQPGDWERAVALAVDT 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+DIL            +++ D + W  +  VN+   +L  + + P L +RGGGS++ 
Sbjct: 85  FGGLDILVNNAGIAGDNTDLMNLDLENWHSVLSVNLDGVFLGLRYSGPALERRGGGSVIN 144

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAITN 227
           ISSI           Y  SK  +  L+K+ A E     IRVN V PG V T     A+  
Sbjct: 145 ISSILGKVGFPGAAPYCASKGAVTLLSKSAALEWAPLKIRVNSVHPGFVETPLVRDALAE 204

Query: 226 SEAGAEKS---LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
            E GAE +   ++  P+ R G   EIA AV FLASD+AS++TG  +V+ GG  A+
Sbjct: 205 REDGAEMAELLVAAHPIGRLGLATEIANAVTFLASDEASFMTGSELVIDGGYTAQ 259


>UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6;
           Bacteroidetes|Rep: Acetoin(Diacetyl)reductase -
           Croceibacter atlanticus HTCC2559
          Length = 254

 Score =  117 bits (282), Expect = 3e-25
 Identities = 71/228 (31%), Positives = 113/228 (49%), Gaps = 2/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +AKRLG +G +VV+         K V+ L +EG+T E     V   E      +    K+
Sbjct: 22  VAKRLGQDGYTVVLNGIDHETGAKRVEELTAEGMTAEYYGFDVTKEEDVTSNIKAIGEKY 81

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +D+L              +   + +  +  +N+ S +  ++ A P L      SI+  
Sbjct: 82  GRIDVLVNNAGGLGGRSRFEEMTTEFYRNVMALNLDSVFFASRAAIPFLKNGEHPSIINY 141

Query: 400 SSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +S A +    P  G YG SK  +  +T+A+A +     IRVN V+PG + T F + I  +
Sbjct: 142 TSNAGWTAGGPGAGIYGTSKAGVHAITRALAKDLAEYGIRVNAVSPGTIDTPFHAQIKET 201

Query: 223 EAGAEKS-LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +     S  +N+ L R G+PE++A  V+FLAS DAS+IT ET+ + GG
Sbjct: 202 KPEVFASWANNIMLGRLGQPEDVASVVSFLASKDASFITAETIQIGGG 249


>UniRef50_A1VQU4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Polaromonas naphthalenivorans CJ2|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 275

 Score =  117 bits (282), Expect = 3e-25
 Identities = 76/230 (33%), Positives = 112/230 (48%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVIC---SRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVA 593
           A+ ++   +GA++ I    S+    +   +  LR+ G T  GV   + +      L   A
Sbjct: 25  ALIEQARKDGAAIHIAAAASQSGDKLESLLGELRAAGATASGVTGDITDPAQCAALVAQA 84

Query: 592 TSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
            +  G +  L            + D     WD  F++N +S+WLLA+ A   L  R  GS
Sbjct: 85  QASGGDLTALVCNAGASGPGQ-LADLPVAQWDTTFNLNTRSAWLLAQAARDSLA-RTRGS 142

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           I  I+S++   P    GAY  +K  L+ L + +A E   + IRVN V PG++ T    A+
Sbjct: 143 ITAIASMSGLTPHPGYGAYSAAKAALIMLCRQLAQEWAADGIRVNTVCPGMIRTPLTEAV 202

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                   K  + VPL R GR E++  AVAFLAS  ASYITG+ +VV GG
Sbjct: 203 YQDADTLLKRQALVPLGRIGRAEDVGAAVAFLASAGASYITGQNLVVDGG 252


>UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=8; Pezizomycotina|Rep:
           Oxidoreductase, short-chain dehydrogenase/reductase
           family - Aspergillus clavatus
          Length = 328

 Score =  117 bits (282), Expect = 3e-25
 Identities = 74/230 (32%), Positives = 118/230 (51%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGAS--VVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
           A+A     EGAS  +V    +ES+  +  + ++  G     +   +   E+ R++ +VA 
Sbjct: 99  AVAILFAMEGASSLIVYLPDEESDAQETKRRVQEIGKECHCLAIDLRKKENCRKVVDVAL 158

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
              GGVD+L            I + DE  W++ FD N+   + LAK   P +  R G +I
Sbjct: 159 QYMGGVDVLVNNAAFQHMVQDISELDEAQWERTFDTNIHPFFYLAKYTLPHM--RSGSTI 216

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTK-FASAI 233
           +  SS+  Y     L  Y  +K  ++  T+A++N+ + + IRVNCV PG + T    S +
Sbjct: 217 INCSSVNHYIGRSDLLDYTSTKGAIVAFTRALSNQQIGKGIRVNCVCPGPIWTPLIPSTM 276

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           T S   A +  S+VP+ R G+P E+A    FLAS D+SYI+G+ +   GG
Sbjct: 277 TTS---AMEQFSSVPMGRPGQPSEVATCFVFLASHDSSYISGQCLHPNGG 323


>UniRef50_UPI000038D860 Cluster: COG1028: Dehydrogenases with
           different specificities (related to short-chain alcohol
           dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep:
           COG1028: Dehydrogenases with different specificities
           (related to short-chain alcohol dehydrogenases) - Nostoc
           punctiforme PCC 73102
          Length = 262

 Score =  117 bits (281), Expect = 4e-25
 Identities = 73/227 (32%), Positives = 112/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A    S GA V+I +R   +V + +   R  G+   G+   VA  E R+ +FE     
Sbjct: 31  AVANEFLSLGAEVIIVARNSQDVDQQLIIWRELGLPAYGITADVATAEGRQAIFEQVGKT 90

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +  +DIL            +LD     +  I   N  S + + +  YP L  R   SIV 
Sbjct: 91  WDKLDILVNNVGTNISKK-VLDYTAAEYQFIIQTNQISIFEMCRLFYPLLQNRENSSIVN 149

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS+A          YG++K  +  LT++++ E   + IRVN VAP  + T    ++ ++
Sbjct: 150 ISSVAGLVSNRTGAPYGMTKAAINQLTRSLSVEWACDQIRVNTVAPWAIRTPLTESVLDN 209

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +   +  LS  P+ R G+PEE+AG VAFL    AS+ITG+ + V GG
Sbjct: 210 QDFLKLVLSQTPMGRVGQPEEVAGLVAFLCMPAASFITGQCITVDGG 256


>UniRef50_Q9A326 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=4;
           Proteobacteria|Rep: 2-deoxy-D-gluconate 3-dehydrogenase
           - Caulobacter crescentus (Caulobacter vibrioides)
          Length = 260

 Score =  117 bits (281), Expect = 4e-25
 Identities = 71/232 (30%), Positives = 117/232 (50%), Gaps = 6/232 (2%)
 Frame = -3

Query: 760 IAKRLGSEGASVVIC-SRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           +AK +   GA +VI  S  E N+  A Q+L + G+ V+     V++    R   E A + 
Sbjct: 26  MAKAMAQAGADIVIWGSNPERNLA-AEQTLTALGVRVKAQTVDVSDEAQVREGMEEAVAA 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-----G 419
            G VD +           S +D   +V+ K+  VN+   +   +EA   +V+R      G
Sbjct: 85  MGRVDSVFANAGIGYGSPSFVDMSTEVYRKVLAVNLDGVFFTLREACRHMVERAKAGDPG 144

Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
           GS+V ++S+AA +      AY  +K  ++ + K++A E     +R N + PG + T   +
Sbjct: 145 GSLVGVASLAAIEGAARNEAYAATKGAVISMIKSVAVEHARYGVRANAILPGWIATDMTA 204

Query: 238 AITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               + A AEK +  VP +R+G PE+  G   +LASD +SY +G T+V+ GG
Sbjct: 205 GAQGNAAFAEKVIPRVPARRWGEPEDFGGMAVYLASDASSYHSGTTLVIDGG 256


>UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=6;
           Bacteroides|Rep: 7-alpha-hydroxysteroid dehydrogenase -
           Bacteroides fragilis
          Length = 259

 Score =  117 bits (281), Expect = 4e-25
 Identities = 71/226 (31%), Positives = 110/226 (48%), Gaps = 2/226 (0%)
 Frame = -3

Query: 754 KRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGG 575
           +R+ SEG  VVI         +    L + G  V  V       +  + L      ++G 
Sbjct: 24  RRIVSEGGKVVIADYSREKADQFAAELSNSGADVRPVYFSATELKSCKELITFTMKEYGQ 83

Query: 574 VDILXXXXXXXX--XXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           +D+L             +I   D   +D+ F +N+  +  L++   P +  +GGG+IV +
Sbjct: 84  IDVLVNNVGGTNPRRDTNIETLDMDYFDEAFHLNLSCTMYLSQLVIPIMSTQGGGNIVNV 143

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +SI+          YG SK  ++ LTK IA +T  +NIR N VAPG+++T  A    N E
Sbjct: 144 ASISGITADSNGTLYGASKAGVINLTKYIATQTGKKNIRCNAVAPGLILTPAALNNLNEE 203

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              +  L        G P+++A  +AFLAS+DA YITG+T+VV GG
Sbjct: 204 V-RKIFLGQCATPYLGEPQDVAATIAFLASEDARYITGQTIVVDGG 248


>UniRef50_Q1DDU7 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2;
           Cystobacterineae|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Myxococcus xanthus
           (strain DK 1622)
          Length = 245

 Score =  117 bits (281), Expect = 4e-25
 Identities = 80/232 (34%), Positives = 117/232 (50%), Gaps = 4/232 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+ L  EGA+V ICSR    + +A ++L   G  +  V C +   +  + L E  T+K
Sbjct: 22  AIAEALVKEGATVAICSRGGEKLERAAKAL---GAAL-AVPCDLTQPQAAKALVETVTAK 77

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAY----PELVKRGGG 416
            GGVD+L               T EQ W   F    +S W+ A +      P + +R  G
Sbjct: 78  LGGVDVLVVNTGGPPSGGFESLTAEQ-WQLGF----QSLWMAAVDGIQAVLPGMKERQWG 132

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
            IV ++S+AA +    L      +  LLGL K ++NE     + +N V PG   T+    
Sbjct: 133 RIVLVTSLAAREAMNNLTISNGLRAGLLGLVKTVSNEVAQHGVTLNAVLPGYHATERMQQ 192

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           +  ++   EK    +P +R GRPEE+A   AFLAS+ ASYITG+++ V GGA
Sbjct: 193 LGLTD---EKVAPQIPARRLGRPEELAALTAFLASEQASYITGQSIAVDGGA 241


>UniRef50_Q126E9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=42; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 256

 Score =  117 bits (281), Expect = 4e-25
 Identities = 70/228 (30%), Positives = 117/228 (51%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           + A+ L   GA VV+   +E  + ++V +LR+EG    GV   V +    +   E A + 
Sbjct: 27  SFARTLCESGARVVLADLREELLQQSVATLRAEGFDASGVAVDVGDPASIQCCAEQAVAN 86

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-WDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
            GG+D L             +D  E   WD++ +VNV+ +WL+ +   P L   G G+IV
Sbjct: 87  LGGLDGLVNNAAVTDSGGRGMDDIEIAKWDQVMNVNVRGTWLMTRACRPALRAGGRGAIV 146

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ++S  A      L AY  SK  ++ +T ++A E   +NI VN +APG+V+ +    +  
Sbjct: 147 NLASDTAMWGAPNLLAYVASKGAVIAMTHSLARELGPDNITVNAIAPGLVLVEATQYV-- 204

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            E+   + +    L+R   PE+++GAV +  SD A ++TG+ + V GG
Sbjct: 205 PESRHRQYIDQRALQREQMPEDVSGAVLYALSDLARFVTGQVLAVNGG 252


>UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3;
           Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase -
           Eubacterium sp. (strain VPI 12708)
          Length = 266

 Score =  117 bits (281), Expect = 4e-25
 Identities = 75/229 (32%), Positives = 111/229 (48%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+    EGA V + +R           + + G  V+ V       E    + E    +
Sbjct: 20  AIAQACAKEGAKVYMGARNLERAKARADEMNAAGGNVKYVYNDATKEETYVTMIEEIIEQ 79

Query: 583 FGGVDILXXXXXXXX--XXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
            G +D+L              I +TD +V+ K  ++N+KS ++ ++ A   + + GGGSI
Sbjct: 80  EGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSVFIASQTAVKYMAENGGGSI 139

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           + ISS+    P     AYG SK  +  LTK IA      NIR N V PG+  T  A    
Sbjct: 140 INISSVGGLIPDISQIAYGTSKAAINYLTKLIAVHEARHNIRCNAVLPGMTATD-AVQDN 198

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            ++      L + P++R G PEEIA AV + ASDDA+Y TG+ + V+GG
Sbjct: 199 LTDDFRNFFLKHTPIQRMGLPEEIAAAVVYFASDDAAYTTGQILTVSGG 247


>UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Burkholderia cenocepacia MC0-3|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia cenocepacia
           MC0-3
          Length = 261

 Score =  117 bits (281), Expect = 4e-25
 Identities = 76/226 (33%), Positives = 109/226 (48%), Gaps = 4/226 (1%)
 Frame = -3

Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
           L S GA+VV     E    + V+ +         V   + N      ++E   +K G +D
Sbjct: 33  LASAGAAVVAADLNEEAAQETVKQIELSSGKAIAVKVDIGNESSILAMYETVQAKLGRLD 92

Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
           +L            + +T  + WDK+  VN++ ++L  +EA   +   G GGSIV ISS+
Sbjct: 93  VLVNNAGIYPKTHFV-ETSAEKWDKVLGVNLRGTFLCMREAIKRMQATGNGGSIVNISSV 151

Query: 391 AAYQPTE-PLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE-- 221
           A+ QP     G YG SK  +  LTK  A E   + IRVN V PG V T+ A+  T +   
Sbjct: 152 ASQQPVIFDNGDYGASKAGVNNLTKVAALEFAGDRIRVNAVLPGGVATEGAAESTKAHQA 211

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            G       +PL R G P +IA AV F AS  + Y+TG+ + V GG
Sbjct: 212 TGPITQPGRMPLGRIGLPSDIARAVLFFASPASDYVTGQLLAVDGG 257


>UniRef50_Q46PX5 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
           NAD-dependent epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 253

 Score =  116 bits (280), Expect = 5e-25
 Identities = 75/229 (32%), Positives = 116/229 (50%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVG-KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           A  +   S+GASVVI  R  S +G K  + L    +        V+  +  RRL +   S
Sbjct: 25  ATVRLFASQGASVVIADR--SALGEKLARELSESSLAAHYSEVDVSREDDTRRLIDDTVS 82

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSI 410
           +FG +DI+            + D   + W ++ DVN+   +L  K A  ++ K+G GG+I
Sbjct: 83  RFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLSNKLAIVQMKKQGTGGAI 142

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           V ++SI  +       +Y  +K  ++ LT+++      + IRVN V PG V T      T
Sbjct: 143 VNMASILGHVGMPGAASYNAAKGGVVNLTRSLGVSHAQDGIRVNAVCPGFVATPLIERAT 202

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             EA A    ++ P+ R G  +E+A AV FLASDDAS+I G +++V GG
Sbjct: 203 E-EARARLVAAH-PIGRLGHADEVAKAVLFLASDDASFIVGTSLMVDGG 249


>UniRef50_A5CY54 Cluster: Dehydrogenases with different
           specificities; n=1; Pelotomaculum thermopropionicum
           SI|Rep: Dehydrogenases with different specificities -
           Pelotomaculum thermopropionicum SI
          Length = 254

 Score =  116 bits (280), Expect = 5e-25
 Identities = 71/227 (31%), Positives = 111/227 (48%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA  L   GA V + SR    + +  Q +  +G     +   V   E    L E A S 
Sbjct: 25  AIAVALAGCGARVAVASRTLKEIEETRQIIAEKGGECLAIPADVTRVEAIYELVEKAYSW 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
              +DIL           ++ D  E+ WD++ D N+K ++   + A  +++  GGG I+ 
Sbjct: 85  HNRLDILVNCAGINIAKFAV-DVTEEDWDRVLDTNLKGTFFCCQAAGKKMIAGGGGRIIN 143

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS  A+       AY  SK  +  LTK +A E    N+ VNCVAP  + T   + +   
Sbjct: 144 ISSQMAHVGYYKRAAYCSSKGGVAQLTKVLAVEWAPHNVNVNCVAPTFLETPLTAPMFED 203

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +      +  +PL + G+PE++ GAV +LASD A+ +TG +++V GG
Sbjct: 204 KDFYNDVIRRIPLGKIGKPEDVVGAVIYLASDAANMVTGSSILVDGG 250


>UniRef50_A4AAT7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; unclassified Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Congregibacter litoralis
           KT71
          Length = 254

 Score =  116 bits (280), Expect = 5e-25
 Identities = 71/234 (30%), Positives = 112/234 (47%), Gaps = 6/234 (2%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A+R    GA V++    ES++       R + +     V  V +              FG
Sbjct: 23  ARRFVDAGAKVMLVDLDESSLRDIASECREDDLRY--TVADVTSETDTAAYVAATVGAFG 80

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
           GVD+L            + + D Q + K+ DVNV   +L  K  +P +   GGGS+V  S
Sbjct: 81  GVDVLLANAGVEGPSAPVSEFDLQSFQKVLDVNVMGVFLGIKHVFPVMAAGGGGSVVITS 140

Query: 397 SIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAP----GIVVTKFASAIT 230
           S+A    T  + AYG SK  ++GL +A A E   +NIRVN + P    G ++    S + 
Sbjct: 141 SVAGVSATPGICAYGTSKHAVIGLMRACAKEGGPQNIRVNTINPSPVEGRMMRSLESGLM 200

Query: 229 NSEAGA--EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
             +  A  E   S +P++R+  PE++A  + FLAS+++ ++ G T +V GG  A
Sbjct: 201 PEDPTAQYEAIKSAIPMERYADPEDVANLMLFLASEESRFLNGATYMVDGGMTA 254


>UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2;
           Euryarchaeota|Rep: Predicted short chain dehydrogenase -
           Methanosphaera stadtmanae (strain DSM 3091)
          Length = 253

 Score =  116 bits (280), Expect = 5e-25
 Identities = 69/231 (29%), Positives = 109/231 (47%), Gaps = 4/231 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           +IA     EGAS ++ +R++  + +    + S G      +  V   E    + ++A  K
Sbjct: 20  SIAYLFAEEGASTILIARRKERLEQITNEINSNGGDASACIGDVTKQEDIDNVVKLALDK 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +DI+           S+   D+ +WDK  DVN+     L +   PE++K  GG+I+ 
Sbjct: 80  YGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRLIRAVIPEMIKNNGGNIIT 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS+          AY  SK  ++GL K  A      NIR N +APG V T+ A+ I   
Sbjct: 140 ISSVGGLIGKISGAAYTASKHGVIGLAKHTAWVYGKHNIRSNVIAPGTVNTEIATTINPG 199

Query: 223 EAGAEKSLSNVPL----KRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
               E   +  P      + G+ +EIA    FLASDD+S++ G+ +   GG
Sbjct: 200 RMDMETYETIDPFVKLSPKLGQSKEIAQIALFLASDDSSFVNGDVIKADGG 250


>UniRef50_Q05528 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=93;
           Bacteria|Rep: 2-deoxy-D-gluconate 3-dehydrogenase -
           Dickeya dadantii (strain 3937) (Erwinia chrysanthemi
           (strain 3937))
          Length = 253

 Score =  116 bits (280), Expect = 5e-25
 Identities = 59/180 (32%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
 Frame = -3

Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
           L E A ++FG VDIL           +I +  E+ WD + ++N+KS + +++    + +K
Sbjct: 75  LVEKAVAEFGKVDILVNNAGIIRREDAI-EFSEKNWDDVMNLNIKSVFFMSQTVARQFIK 133

Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
           +G GG I+ I+S+ ++Q   P+ +Y  SK  ++G+T+ +ANE    NI VN +APG + T
Sbjct: 134 QGHGGKIINIASMLSFQGGIPVPSYTASKKRVMGITRIVANEWAKHNINVNAIAPGYMAT 193

Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
                +   +  +++ L  +P  R+G P+++ G   FLAS  + Y+ G T+ V GG  AR
Sbjct: 194 NNTQHVRADQDRSKEILDRIPAGRWGLPQDLQGPAVFLASSASDYVNGYTIAVDGGWLAR 253


>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
           Oxidoreductase - Oceanobacillus iheyensis
          Length = 244

 Score =  116 bits (279), Expect = 6e-25
 Identities = 70/231 (30%), Positives = 115/231 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK   SEGA +++    E         L+S+G     +   V N E  + ++  A   
Sbjct: 20  ATAKLFASEGAKLILVDMNEEKGASIEAELKSQGSEAIFIKADVTNEEQVKNIYTTAIDT 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG VDIL           +   T  + W K  +V++   +L+A+ A  E +K G G IV 
Sbjct: 80  FGKVDILFNNAGIGAVKPTEELTYAE-WRKTVEVDLDGVFLVAQAAIKEFLKAGSGVIVN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +S+  +  +    AY  +K  ++ LT+++  E    NIRVN + PG + T         
Sbjct: 139 TASMYGWVGSPGSAAYNAAKAGVVNLTRSLGLEYAARNIRVNALCPGFIDTAIL-----G 193

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           ++  E  ++  P+ R G+ EE+A AV F+ASDD+S++TG +++V GG  A+
Sbjct: 194 DSDREALINTTPMNRLGKSEEMAKAVLFMASDDSSFMTGNSLIVDGGYTAQ 244


>UniRef50_Q57A51 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=4; Brucella|Rep:
           Oxidoreductase, short-chain dehydrogenase/reductase
           family - Brucella abortus
          Length = 250

 Score =  116 bits (279), Expect = 6e-25
 Identities = 68/227 (29%), Positives = 110/227 (48%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI+     +GA V++     +       +L ++G   EG    V + +    L +   S+
Sbjct: 21  AISSGAAEQGARVILVDIDGTAAKAQADALTAKGFVAEGHALDVTDRDAVAALADDILSR 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+D+L                  +VWD++  VN++ ++ ++    P L K   G++V 
Sbjct: 81  FGGLDVLVNNAGVAGRAAFDQPEAVEVWDRVIGVNLEGAFNVSHALVPAL-KAAKGNVVH 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           + S+A +        Y VSK  +  LT+ +A +     IRVN VAPGI++++ A A  N 
Sbjct: 140 LCSVAGFVSGGSTAGYVVSKGAIRSLTQVMARDLAPHGIRVNAVAPGIMMSEMAVAQLNR 199

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             G +  ++ V +KR G   E+   V FLAS  ASYITG  + V GG
Sbjct: 200 PGGTDWFMNRVMMKRIGETSEVVDPVVFLASPMASYITGTILPVDGG 246


>UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;
           Oceanicola granulosus HTCC2516|Rep: Short-chain alcohol
           dehydrogenase - Oceanicola granulosus HTCC2516
          Length = 245

 Score =  116 bits (279), Expect = 6e-25
 Identities = 62/179 (34%), Positives = 94/179 (52%)
 Frame = -3

Query: 610 RLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELV 431
           RL   AT++FGG+D L           ++ D  E++WD I D+N K  WL  +   P +V
Sbjct: 68  RLVAEATARFGGIDALVNNAGIAVPGDTVTDASEEMWDDILDINAKGVWLGMRAVLPGMV 127

Query: 430 KRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
           +RGGG I  ++S AA+       AY  SK  +L LT+    +     I++N V+PG  +T
Sbjct: 128 ERGGGHICNVASTAAHIGLPGAAAYCASKGAVLALTRQAGVQYAPLGIKINSVSPGTTMT 187

Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
                +T+++  A   L+  P+ RF   +E+A  + FL SD AS++ G  V V GG  A
Sbjct: 188 GIQKNVTDAQRAAFLPLT--PIGRFAEADEVARVILFLCSDGASFMAGADVSVDGGMVA 244


>UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; gamma proteobacterium HTCC2207|Rep: Short-chain
           dehydrogenase/reductase SDR - gamma proteobacterium
           HTCC2207
          Length = 255

 Score =  116 bits (279), Expect = 6e-25
 Identities = 73/226 (32%), Positives = 111/226 (49%), Gaps = 1/226 (0%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           AK L + GA VV+ +R+   +   V  +++ G     V   V + E     F+   + FG
Sbjct: 26  AKILAARGAKVVVAARRVDRLEALVAEIQAAGGEACAVAMDVTSAESVTAAFDKGEAAFG 85

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFI 401
            + ++           + L  DE  WD + D N+K  W++A+EA   +V  G GGSIV  
Sbjct: 86  TITVVSNNAGVADGKSA-LKADEASWDWVVDTNLKGVWMVAQEAAKRMVAAGVGGSIVNT 144

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +SI   +       Y  SK  ++ LTKA A E   + IRVN + PG  +T+   ++ +S 
Sbjct: 145 ASILGLRVAFAQSVYSASKAGVIQLTKAQALEWGRKGIRVNALCPGYFLTEMTESLFDSP 204

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             A K L++ PL R G  +EI+G    LA D   Y+TG  + V GG
Sbjct: 205 ESA-KFLASSPLGRAGNMDEISGPFLLLAGDAGGYLTGVALPVDGG 249


>UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 251

 Score =  116 bits (279), Expect = 6e-25
 Identities = 69/231 (29%), Positives = 116/231 (50%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+A  L +EG  + + SR E+ + +    L + G         V + E  R+      + 
Sbjct: 22  AMAMALAAEGTRIALVSRDEARLNEVAAELIAAGGDAAIFRADVTSEEQVRQAERAILAT 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G VDIL            +  T E+ W ++ D NV +++L+ +   P +  RG G I+ 
Sbjct: 82  YGKVDILINNAGVNVRKPVVEFTVEE-WHRVMDTNVTAAFLMCRSFVPAMSGRGYGRILN 140

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++SI ++       AY  SKT LLG+T+ +A E   + I VN ++PG   T+    +  +
Sbjct: 141 MTSIMSHVSLPGRIAYSTSKTALLGMTRTLALELAPQGITVNGISPGPFGTEMNKPLMEN 200

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
                + LS++PL R+G+ EEI     +L S+DA +ITG  +++ GG  AR
Sbjct: 201 PETNAQFLSSIPLGRWGKVEEIGQLAVYLCSEDAGFITGTDILIDGGWCAR 251


>UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus
           sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp.
           B14905
          Length = 252

 Score =  116 bits (279), Expect = 6e-25
 Identities = 69/230 (30%), Positives = 114/230 (49%), Gaps = 3/230 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A + +L S GA VVI    +    + ++ ++ +G     V   V+  E   +    A   
Sbjct: 20  ASSLKLASNGAKVVIVDFNKETGEETLKLVKEQGGEGIFVQADVSKSEDVEKYVNAAVET 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +D+             + +  +  +D+I  +NVK  +L  K     +  +G GSI+ 
Sbjct: 80  YGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVFLGLKHVIKVMEGQGSGSIIN 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +S A  +    +  Y  SK  ++GLTK+ + E V + IR+N + PG V T   +++T  
Sbjct: 140 TASTAGVRSEHSMAVYSASKHAVIGLTKSASLEYVKKGIRINAICPGGVETALTNSVTAM 199

Query: 223 -EAGA--EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            E G    + + N+ + R+ +PEE+A  V FLASD ASY+TG  VVV GG
Sbjct: 200 FETGGYIPEEIPNMRMGRYAKPEELAEMVVFLASDKASYMTGSIVVVDGG 249


>UniRef50_A0Z4N7 Cluster: Short chain dehydrogenase; n=2;
           Bacteria|Rep: Short chain dehydrogenase - marine gamma
           proteobacterium HTCC2080
          Length = 252

 Score =  116 bits (279), Expect = 6e-25
 Identities = 74/232 (31%), Positives = 115/232 (49%), Gaps = 1/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA  L  EGASV++           V  +   G T    V  V++     ++ E A   
Sbjct: 21  AIACALAREGASVLVVDFNGDTAKDTVDLILGAGGTATAHVADVSDEGRVAQMVEAAVDA 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+ +             I     +V+D+   + + +++L  K     +++ GGGSIV 
Sbjct: 81  FGGLQVACNSAAVSRGSGPIHGFTREVFDQTLALCLTNTFLCMKYEIAHMLEHGGGSIVN 140

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS A+ +      AY  +K+ +  LTK+ A+E  H+ IR+N V+PG++ T       + 
Sbjct: 141 ISSNASLRGQPYNTAYAAAKSGVNLLTKSSASEYGHKGIRINAVSPGVIRTPGVERYFDE 200

Query: 223 EAGAEKSLSN-VPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           +    + L     ++R G PEEIA AV FLASD AS+ITG+ + V GGA  +
Sbjct: 201 QPKIAEGLKQAAAMRRLGEPEEIAEAVCFLASDRASFITGQLLSVDGGAAVK 252


>UniRef50_A0TVV4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Burkholderia cenocepacia MC0-3|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia cenocepacia
           MC0-3
          Length = 259

 Score =  116 bits (279), Expect = 6e-25
 Identities = 69/229 (30%), Positives = 107/229 (46%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSL--RSEGITVEGVVCHVANHEHRRRLFEVAT 590
           A A  +   GA VVI  R       A Q++  R          C++      + L + A 
Sbjct: 25  ASALGMAEHGAKVVISGRNGDVCETAAQAINERIGSRAAMPFACNIGRKAELQNLVDAAN 84

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
            ++G VDI+           S+LD  ++ ++K   VNV+S+  LA+   P +++RG G  
Sbjct: 85  GEWGRVDIVMANAAIHPWVGSVLDLQDETFNKFMQVNVQSNIWLAQMTMPGMIERGYGRF 144

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           + ++S+         G YG++K   + L + +A E   + I  NC+APG   T+ A +  
Sbjct: 145 ISVASVVGLFGDPVTGTYGLTKAADMQLVRNLATEFAAKGITANCIAPGTFKTEMARSQW 204

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             +A  E      P +RFG  EEIAG    LAS    YI G+T+ V GG
Sbjct: 205 EDDAMVEWYRGRNPSQRFGEVEEIAGLAVLLASPSGGYINGQTIAVDGG 253


>UniRef50_A0M4X9 Cluster: Short-chain dehydrogenase/reductase family
           protein; n=2; Flavobacteriaceae|Rep: Short-chain
           dehydrogenase/reductase family protein - Gramella
           forsetii (strain KT0803)
          Length = 252

 Score =  116 bits (279), Expect = 6e-25
 Identities = 67/218 (30%), Positives = 112/218 (51%)
 Frame = -3

Query: 736 GASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXX 557
           GA V+  +R E ++      L+ EG  V G+V   A  E  +++      ++  +DIL  
Sbjct: 30  GAEVLFTARNEKDIKLLETELKEEGHQVTGLVADSAKPEDIKKIKNWIAERWNSLDILVN 89

Query: 556 XXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQP 377
                    +I D  E+ + K+ ++N+ + + +++  YP L K G  SI+ I+S AA Q 
Sbjct: 90  NAGINIRKQAI-DYSEEEFRKVLEINLVAPFEISRALYPFLKKSGKASIINIASSAAIQD 148

Query: 376 TEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLS 197
                 Y +SK+ LL  ++++A E   + IRVN V+P    T       ++E   +  LS
Sbjct: 149 VGTGTPYAMSKSGLLQQSRSLAVEWAEDQIRVNSVSPWFTKTPLTEGYLHNEKKMDSILS 208

Query: 196 NVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
             PLKR    EEI+  ++FLA D +S++TG+ +V  GG
Sbjct: 209 RTPLKRVAEAEEISSIISFLAMDKSSFVTGQNIVADGG 246


>UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rhodopseudomonas palustris BisB18|Rep: Short-chain
           dehydrogenase/reductase SDR - Rhodopseudomonas palustris
           (strain BisB18)
          Length = 254

 Score =  116 bits (278), Expect = 8e-25
 Identities = 74/230 (32%), Positives = 113/230 (49%), Gaps = 4/230 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAV----QSLRSEGITVEGVVCHVANHEHRRRLFEVA 593
           +A+R    G  V I SR  S    AV    ++L ++GI V G    ++N E  R +    
Sbjct: 30  VARRFAGAGCRVAIASRSASPAAAAVLAEIEALGAQGIAVAG---DISNSEDARAMVGEV 86

Query: 592 TSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
            ++FG +D+L               TD  ++   FD NV  +  + + A P L   GG  
Sbjct: 87  VARFGRIDVLVNCAGVAEYRAFEA-TDLAMFRATFDTNVFGTVAMIQAALPHLTAPGGRI 145

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           I F S++A  +P      Y  SK  +  LT A+A E     I VN +APG++ T+  +AI
Sbjct: 146 INFSSALAT-RPIPTASIYAASKAAVSALTHALAKEFGPRGITVNAIAPGVIETEMTAAI 204

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                 A K+++  PL R G+ +++AG   FLAS DA ++TG T++  GG
Sbjct: 205 LAERGAAIKAMT--PLGRIGQTDDVAGLALFLASHDAGWLTGRTIIADGG 252


>UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=1; Blastopirellula marina DSM 3645|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Blastopirellula marina DSM 3645
          Length = 258

 Score =  116 bits (278), Expect = 8e-25
 Identities = 72/232 (31%), Positives = 113/232 (48%), Gaps = 1/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATS 587
           AIA+ L   GASV I +R +  +  A Q + +   + V   +C +A+      L +    
Sbjct: 26  AIARGLAEAGASVCITARHQQELETAAQEIGAGLDVRVAWRICDMADRAAVDALADGVLE 85

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           +FG VDIL            +  TDE  WD + ++N  S   LA++  P +++R  G I+
Sbjct: 86  EFGQVDILFNNAGTNQPQLLVETTDES-WDHVLEINFTSCMRLARKLAPGMIERRWGRII 144

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            +SS+ A       G Y  +K  L  +T+A A E     I VNC+APG + T    ++ N
Sbjct: 145 HLSSVLAVVSNPGRGNYSGTKGALSAMTRAHALELGPHGITVNCLAPGPIATDLPMSLLN 204

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
            E   ++      + R+G  +++ G    LASD  +YITG T++V GG   R
Sbjct: 205 DEQ-KQRFAERTAVLRWGETKDLVGPALLLASDAGAYITGTTLLVEGGMICR 255


>UniRef50_A3XJH6 Cluster: D-mannonate oxidoreductase; n=7;
           Bacteroidetes|Rep: D-mannonate oxidoreductase -
           Leeuwenhoekiella blandensis MED217
          Length = 271

 Score =  116 bits (278), Expect = 8e-25
 Identities = 79/244 (32%), Positives = 124/244 (50%), Gaps = 14/244 (5%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+ + L + GA VVI  R ++ V   V S++ +G    GVV  V +        +   + 
Sbjct: 24  AMTRSLAAAGAHVVILGRNQAKVDALVDSIKQDGDQASGVVADVTSKAALIEAKDEIANH 83

Query: 583 FGGVDILXXXXXXXXXXXSIL------DTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 422
            G +D+L            IL      D D +   K+ D+N   S+L  +   P L K  
Sbjct: 84  LGYIDVLINAAGGNMKGALILPEQTLADADVEEMRKVIDLNYIGSFLPTQVFLPLLEKSK 143

Query: 421 GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVH--EN-IRVNCVAPGIVVT 251
            GS++ ISS+AA+ P   +  Y  +K+ +  LT+ +A E     EN IRVN +APG  +T
Sbjct: 144 KGSVLNISSVAAHLPLTRVMGYASAKSAIENLTQFLAIEFAQKQENPIRVNALAPGFFLT 203

Query: 250 KF-ASAITNSEAG----AEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
           +     +TNS+       EK +++ PL +FG P++++GA+ +L SD AS++TG  V V G
Sbjct: 204 EQNRELLTNSDGSLTDRGEKIIAHTPLGKFGDPQDLSGAIHWLCSDAASFVTGTVVTVDG 263

Query: 85  GAPA 74
           G  A
Sbjct: 264 GFKA 267


>UniRef50_Q3INX8 Cluster: Probable dehydrogenase/ reductase 6; n=1;
           Natronomonas pharaonis DSM 2160|Rep: Probable
           dehydrogenase/ reductase 6 - Natronomonas pharaonis
           (strain DSM 2160 / ATCC 35678)
          Length = 251

 Score =  116 bits (278), Expect = 8e-25
 Identities = 81/235 (34%), Positives = 113/235 (48%), Gaps = 4/235 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI+    + GA VV  SR ES+V   V+ + S G+        VA+ +     FE     
Sbjct: 22  AISLGFAAAGADVVPLSRTESDVEAVVEDIESHGVESRVETLDVADSDAVEACFERIDDA 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV----WDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
            G +D++             L T E V    +D + DVN+  ++  A+ A P L +  GG
Sbjct: 82  LG-IDVVVNNAGINPDAA--LGTPESVPDEGFDSVLDVNLGGAFACARAAEPTL-RDNGG 137

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           S++ ++S+           Y  SK  L+GLTK++A +   + +RVNC+APG V T     
Sbjct: 138 SLINVASVGGLVGLPRQHPYVASKHGLVGLTKSLALDWAPD-VRVNCLAPGYVATDLTDD 196

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           +  +E          PL RF  PEEIAG   FLASD ASY TGE   V GG  AR
Sbjct: 197 LQENEDLRRSIERRTPLDRFAEPEEIAGPAVFLASDLASYATGEVFAVDGGWTAR 251


>UniRef50_Q9EWT4 Cluster: Putative oxidoreductase; n=2;
           Streptomyces|Rep: Putative oxidoreductase - Streptomyces
           coelicolor
          Length = 266

 Score =  115 bits (277), Expect = 1e-24
 Identities = 77/231 (33%), Positives = 107/231 (46%), Gaps = 1/231 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+RL +EGA V++         +    L  +G+      C V++ E        A   
Sbjct: 24  ATARRLATEGARVLLTDVDLVGARRTAAELADDGLDATAFACDVSDRESVETAVAHAVET 83

Query: 583 FGGVDILXXXXXXXXXXXSIL-DTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           FGG+D+L            +  D  + VW +  DV +  +    + A P L   G G+IV
Sbjct: 84  FGGLDVLVNNAFACTPDAPLFEDEPDDVWARDLDVTLTGAQRCCRAALPHLAASGRGAIV 143

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            I S+   Q      AY  +K  L  LT+ +A       +RVN V PG V T  A    +
Sbjct: 144 SIGSVNGVQDFGN-HAYSAAKAGLASLTRTLAGHAGPRGVRVNLVTPGTVRTT-AWEGRD 201

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            E  A + L   PL R G PE++A AVAFLAS DA++ITG T+ V GG  A
Sbjct: 202 EELAAVRGL--YPLGRVGEPEDVAAAVAFLASRDAAWITGTTLAVDGGLTA 250


>UniRef50_Q89EA2 Cluster: Gdh protein; n=3; Bradyrhizobium|Rep: Gdh
           protein - Bradyrhizobium japonicum
          Length = 278

 Score =  115 bits (277), Expect = 1e-24
 Identities = 85/238 (35%), Positives = 117/238 (49%), Gaps = 11/238 (4%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLR----SEGITVEGVVCHV------ANHEHR 614
           A+A RL  EGA+V I      + GKA ++L     + G    G + HV       + +  
Sbjct: 31  AVAVRLAQEGATVAI--NYFDHPGKAEETLALARTASGDRGHGRLDHVIVQADIGSEQDI 88

Query: 613 RRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPEL 434
             +FE   +++  +D L           S    D + + +I DVN+  + L A++A    
Sbjct: 89  AAMFETILARWKRLDCLVNNAGFQRESPSDA-LDVETYRRIIDVNLNGAVLCAQKALAHF 147

Query: 433 VKRGGG-SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
           V RGGG SI+  SS+    P     AY +SK  L  LT+ +A E     IRVN V PG +
Sbjct: 148 VARGGGGSIINCSSVHQIIPKPGYLAYSISKGGLANLTRTLALEFARHGIRVNAVGPGAI 207

Query: 256 VTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            T   +A T          S++PL R G PEEIA   AFLASDDASYITG+T+   GG
Sbjct: 208 DTPINAAWTGDPEKRGVVTSHIPLGRVGTPEEIAAVFAFLASDDASYITGQTIYACGG 265


>UniRef50_Q7MYJ9 Cluster: Similar to 3-oxoacyl-acyl carrier protein
           reductase; n=1; Photorhabdus luminescens subsp.
           laumondii|Rep: Similar to 3-oxoacyl-acyl carrier protein
           reductase - Photorhabdus luminescens subsp. laumondii
          Length = 247

 Score =  115 bits (277), Expect = 1e-24
 Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 1/230 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAV-QSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           I K L ++   VV   +   N  + +   +  +G   EG  C V+N +    L     S+
Sbjct: 21  IVKMLAAQNYHVVFTYKSSINEAQILCHDIEQQGYRCEGYQCDVSNAKEVTTLSAELISQ 80

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G    +            +++  E+ W  +   N+ S +L+     PE++  G G I+ 
Sbjct: 81  YGAPYAIINNAGITQDAL-LINMKEEEWHNVISTNLSSIYLVNHSFLPEMITAGEGCIIH 139

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS+ A++       Y  +K  ++G+T+++A E    N+RVN VAPG++ T+  + I   
Sbjct: 140 MSSVTAFKANSGQVNYAATKAAMIGITRSLAVEVGRFNVRVNTVAPGLIDTEMLAHIPAP 199

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
               +K LSN+PL R G  E+IA  V FL S    YITG+T V+ GG  A
Sbjct: 200 H--RKKLLSNIPLGRLGSVEDIALTVNFLLSPGGRYITGQTFVIDGGMTA 247


>UniRef50_Q46MD0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Ralstonia eutropha JMP134|Rep: Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 258

 Score =  115 bits (277), Expect = 1e-24
 Identities = 69/228 (30%), Positives = 120/228 (52%), Gaps = 2/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A+ +   GA VV+ +R+ S +   V+ L + G     V   V++       +  A S+ 
Sbjct: 28  VAELMAEAGAKVVLAARRASLLEDHVERLLTAGYVASSVPLDVSDSGSIAESWCQAESQV 87

Query: 580 GG-VDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           GG +DIL            +    E + D++FD+N + ++LLA++A   +  R  GSI+ 
Sbjct: 88  GGQIDILFNNAGVIYTERFLSQQPEDI-DRVFDINFRGAFLLAQQAAKGMAARRSGSIIN 146

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S +  +    + +YG SK  L+ LT+ +A E   + +RVN + PG   T   ++    
Sbjct: 147 VASTSGLRAGGYMTSYGASKAALISLTQTMALELAGKGVRVNALCPGNFRTDMHASF--E 204

Query: 223 EAGAEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E G E++L   +P+++ G  E++ GA   LASD  SY+TG ++VV GG
Sbjct: 205 EKGLEENLIKRIPMRKIGEVEQLDGATLLLASDAGSYMTGSSIVVDGG 252


>UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1;
           Rhizobium sp. NGR234|Rep: Putative uncharacterized
           protein - Rhizobium sp. (strain NGR234)
          Length = 244

 Score =  115 bits (277), Expect = 1e-24
 Identities = 71/231 (30%), Positives = 115/231 (49%), Gaps = 7/231 (3%)
 Frame = -3

Query: 742 SEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC---HVANHEHRRRLFEVATSKFGGV 572
           S G  +    R     G    + R   I +EGV      V +  +  R      S  G +
Sbjct: 15  STGIGLETIKRIREEGGTVFAAHRRGKIDIEGVASISLDVTDEGNWTRAISKVVSAAGRL 74

Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSI 392
           DIL            + +T  + W ++ D N+ S +L  + A P + + GGG+IV + SI
Sbjct: 75  DILINNAGVRESGS-VEETSLEQWRRLIDTNLTSIFLGCRAAVPAIRQAGGGAIVNVGSI 133

Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV----VTKFASAITNS 224
              + TE + AY  SK+ +  +T ++A +   +NIRVN V P  +    VT + ++  ++
Sbjct: 134 TGIRGTENMVAYSASKSGITSMTSSLALDLASDNIRVNAVCPAAIRTRMVTNWLNSSQDT 193

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           +A     L+  P+ R GRP+E+A  +AFLASDD+S++TG ++ V GG   R
Sbjct: 194 DAAEAAVLAKHPIGRIGRPDEVASVIAFLASDDSSFMTGMSIPVDGGRSIR 244


>UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU -
           Streptomyces sp. Tu6071
          Length = 244

 Score =  115 bits (277), Expect = 1e-24
 Identities = 72/230 (31%), Positives = 111/230 (48%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A      GA V +  R E    + V+++   G   + +   +      RRL + A ++
Sbjct: 18  ATAMAFAGRGADVAVTGRDEQRGRQVVKAIAEAGGVADFIAAELRGESSARRLAQAAVAR 77

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D+L           +   T+   +D +F +NV+  + L  E  P + +RG G+IV 
Sbjct: 78  FGRIDVLVNNAGVFPFGPTERTTEAD-FDAVFGLNVRVPYFLVAELAPAMARRGHGAIVN 136

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +++ AA      LG YG SK  L+ LTKA A E     +RVN V PG   T+        
Sbjct: 137 VTTAAAAYGAAGLGLYGASKAALVLLTKAWAAEYGPRGVRVNAVGPGPTRTE---GTAPR 193

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            A  +++    P +R G  EEIAGA+ FLAS+ +S++ G  + V GG  A
Sbjct: 194 GAALDRAALAGPARRPGTAEEIAGAIVFLASEQSSFVHGAVLPVDGGRVA 243


>UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier
           protein] reductase; n=1; Candidatus Kuenenia
           stuttgartiensis|Rep: Similar to 3-oxoacyl-[acyl carrier
           protein] reductase - Candidatus Kuenenia stuttgartiensis
          Length = 254

 Score =  115 bits (277), Expect = 1e-24
 Identities = 68/227 (29%), Positives = 109/227 (48%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           ++A  L   GA V + SR  S+V +  Q +   G+    +   V   E   ++ E+  SK
Sbjct: 25  SMALALSESGAHVAVASRTFSDVEETAQEIEGNGVKSLPIAADVTKPEDVTKMVEMVLSK 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           F  +DIL            I D     W K+ ++N+ S++L  K     ++ +  G I+ 
Sbjct: 85  FKTIDILVSNVGAFIGGS-IQDISLDDWHKMIEINLTSTYLCVKTVGKHMLDKKCGKIIT 143

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS           AY   K  ++ LTKA+A E    NI VN +AP  + T+    +   
Sbjct: 144 MSSALGIFGANRSSAYCSGKGGVIQLTKALAIEWAKYNINVNSIAPYSMETETTREMLKD 203

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E   +  +S +PL+R G+P +++G V FLAS  + YITG+ + V GG
Sbjct: 204 EKIKQAIISKIPLQRIGQPSDLSGTVVFLASKASDYITGQVIFVDGG 250


>UniRef50_Q0RIJ2 Cluster: Putative short chain
           dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep:
           Putative short chain dehydrogenase/reductase - Frankia
           alni (strain ACN14a)
          Length = 261

 Score =  115 bits (277), Expect = 1e-24
 Identities = 78/233 (33%), Positives = 116/233 (49%), Gaps = 4/233 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ L   GAS+V+     +   ++  +L   G  V  V C VA  +        A  +
Sbjct: 31  AFARELAERGASIVLADIDAAAAERSAAALTEAGHPVLPVRCDVAAEDTVDAAVAAAVER 90

Query: 583 FGGVDILXXXXXXXXXXXSI----LDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
           FGG+DIL           ++    L  D+    ++FDVNV      +  A P +  RGGG
Sbjct: 91  FGGIDILVNNAGRHLTRYNLPFQTLARDDV--RELFDVNVMGVVNCSLAARPSMAARGGG 148

Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           SI+ ISS+A++  T P   Y VSK  + GLT A A E   +NIRVN ++PG++ T+ A A
Sbjct: 149 SIINISSMASHLGTSP---YAVSKLAVRGLTVAFATEFAPDNIRVNAISPGLMDTESAMA 205

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAP 77
              +E   +       + R GR  +I  A+ +L S +  ++TGET+ V GG P
Sbjct: 206 DLPAELVRDIIDQRQLIHRQGRVADIVAALIYLCSAEGGFVTGETLKVTGGFP 258


>UniRef50_Q0LZD3 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:Male sterility-like
           precursor; n=1; Caulobacter sp. K31|Rep: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:Male sterility-like
           precursor - Caulobacter sp. K31
          Length = 275

 Score =  115 bits (277), Expect = 1e-24
 Identities = 75/237 (31%), Positives = 113/237 (47%), Gaps = 3/237 (1%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A  L  +GA VV+   +   +      L++EG  V      + + +  R + + A   FG
Sbjct: 23  ALALAEQGARVVLTDLRAPELSAVTDRLKAEGHDVACKAGDITSEDDIRAVVDFAAETFG 82

Query: 577 GVDILXXXXXXXXXXXSILDTDE---QVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           GVDIL             LD  +   ++WD++  +N +   L  K A P ++ RGGGSIV
Sbjct: 83  GVDILDNNAGATGFSSRDLDIPDMPVELWDQVQSINARGPMLFCKYAIPSMLARGGGSIV 142

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ISS  +        AY  SK  +  LT+ +A     + +RVN +A G+++         
Sbjct: 143 NISSGQSLSGDVSNFAYASSKAAVNALTRHLATAYSPKGVRVNAIAAGLIIQPGMEQRLP 202

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL*VVA 56
           +    E  LS+  + R G P +IA  V FLASD +SY+TG+ + V GG  A L  VA
Sbjct: 203 AHI-QEIFLSHCLVPRLGTPRDIANMVVFLASDLSSYVTGQILSVDGGFTAHLPSVA 258


>UniRef50_A4FCN3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 267

 Score =  115 bits (277), Expect = 1e-24
 Identities = 75/232 (32%), Positives = 113/232 (48%), Gaps = 2/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+    EGA V++ +R E+ +    + +R+ G T   VVC +A+    R   + A + 
Sbjct: 36  AAARLFAREGARVLLAARTEAQLKTVAEEIRAAGGTANYVVCDLADATSVRAAVDRAVNL 95

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWL-LAKEAYPELVKRGGGSIV 407
           +G +DI             +    E  +D I+DVN+K  WL +  E        G G++V
Sbjct: 96  YGRLDIAFNNGATIQQPGPMDQMPEADFDHIYDVNLKGVWLAMVAEIAAIRTTAGTGAVV 155

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
             SS+ +      L AYG  K  +  LT++ A     E IRVN +APG   T+       
Sbjct: 156 NNSSVGSLMGNPELPAYGAMKRAVNSLTESAAVTYGPEGIRVNAIAPGNTRTEMIRTWEQ 215

Query: 226 SEAGAEKSLS-NVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
              G  + L+ + PL+R   P+EIA A A+L SD +SY+TG  + V GGA A
Sbjct: 216 GSPGLRERLTAHTPLRRAADPQEIAQAAAWLLSDRSSYVTGTVLRVDGGARA 267


>UniRef50_A0GVX4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Burkholderia phytofirmans PsJN|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia phytofirmans
           PsJN
          Length = 259

 Score =  115 bits (277), Expect = 1e-24
 Identities = 73/232 (31%), Positives = 115/232 (49%), Gaps = 6/232 (2%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRS-EGITVEGVVCHVANHEHRRRLFEVATSK 584
           IA+ L +EGA VVI +R+E ++ +A   +R   G  V  +       E   R+  +A ++
Sbjct: 23  IARTLAAEGAQVVISARREEDLKRAAYEIRELTGNAVTWIAADCRKAEDCERVATIARAE 82

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+DIL            +L  D+  W +  + N+     + ++    + +RGGGSI+ 
Sbjct: 83  FGGIDILVNNDGAPPVGP-VLSFDDAAWHRAVEQNLMYPVRMVRQVADSMKERGGGSILN 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTK-----FAS 239
           I++I+A QP   LG    +   ++G  K ++ E     I VN + PG + T      FA+
Sbjct: 142 ITAISAIQPIRDLGLSVATWGGVIGYAKTLSMELAEFGINVNTICPGYIDTSRLRKVFAA 201

Query: 238 AITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                EA   + L +VPL R G  ++IA  VA L S   +YITG  + V GG
Sbjct: 202 GDEPDEAVRARLLQDVPLGRVGSVDDIANLVALLVSPRGAYITGTAIQVDGG 253


>UniRef50_Q5V623 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Haloarcula marismortui|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 280

 Score =  115 bits (277), Expect = 1e-24
 Identities = 76/240 (31%), Positives = 119/240 (49%), Gaps = 9/240 (3%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNV-GKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           IA R    G  VV+CSR   +V   A +  ++    V  V C V + E  R L +    +
Sbjct: 24  IAARFAEAGGDVVVCSRTYEDVEAVATELTQTHDGRVVPVECDVTDREAVRDLVDTTIQE 83

Query: 583 FGGVDILXXXXXXXXXXXSILDT-DEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           FG + +L           ++L   DE+ ++ + D+N+KS +LL+KE  P +V  GGGSI+
Sbjct: 84  FGDIRVLVNNAGGADESANLLHRCDEETFESMVDLNLKSQFLLSKEVLPAMVAAGGGSII 143

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA-IT 230
            + S+        L  Y  +K+ LL L++ IA       +R N ++   + T    A + 
Sbjct: 144 HMGSVNGLFGIG-LSGYSEAKSGLLALSRNIAAHYGQHGVRSNVISAATIETANRRAEME 202

Query: 229 NSE------AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
           N+E      +  E+ L   PL RFG P E+A    FLAS+ +S++TGE +V+ GG    L
Sbjct: 203 NTEERTGETSARERWLDQYPLGRFGTPREVADTTLFLASEMSSFLTGENLVLDGGLTTSL 262


>UniRef50_Q7D5G1 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=18;
           Corynebacterineae|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Mycobacterium
           tuberculosis
          Length = 293

 Score =  115 bits (276), Expect = 1e-24
 Identities = 75/228 (32%), Positives = 112/228 (49%), Gaps = 2/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVV-CHVANHEHRRRLFEVATSK 584
           +A  L + GA+V+I  R    +  AV+ + +      G     + + E   R+ + AT+ 
Sbjct: 40  VAAGLVAAGAAVMIVGRNPDKLAAAVKDIEALKTGAIGYEPADITDEEQTLRVVDAATAW 99

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +  +            I   D Q W +  D+NV  +  + K A  ELV+ GGGS V 
Sbjct: 100 HGRLHGVVHCAGGSQTIGPITQIDSQAWRRTVDLNVNGTMYVLKHAARELVRGGGGSFVG 159

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISSIAA       GAYGV+K+ +  + K  A+E     +RVN + PG++ T     +T S
Sbjct: 160 ISSIAASNTHRWFGAYGVTKSAVDHMMKLAADELGPSWVRVNSIRPGLIRTDLVVPVTES 219

Query: 223 -EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            E  A+  +   PL R G  E++A    FL SD AS+ITG+ + V GG
Sbjct: 220 PELSADYRVC-TPLPRVGEVEDVANLAMFLLSDAASWITGQVINVDGG 266


>UniRef50_Q2CJE1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Oceanicola granulosus HTCC2516|Rep: Short-chain
           dehydrogenase/reductase SDR - Oceanicola granulosus
           HTCC2516
          Length = 250

 Score =  115 bits (276), Expect = 1e-24
 Identities = 76/227 (33%), Positives = 113/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA RL ++G +VV C    S    A +         E VV  +A+ E   RL  VA ++
Sbjct: 18  AIAARLLADGFAVVACDL--SAFADAAEGR-------EDVVADIADPETPARL--VAAAQ 66

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
             G               +  +TD+  W +I DVN+ + + LA+ A PE++  GGGS+V 
Sbjct: 67  RAGRLAALVNNAGIGGAKAAAETDDASWSRILDVNLGAGFRLARAALPEMIAGGGGSLVN 126

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S+          AY  SK  + GLT+ +A +     +R N VAPG++ T     +   
Sbjct: 127 VASVYGQLGFRTTAAYAASKAGIEGLTRQMAVDYGPRGVRANAVAPGLIETALTRRLLED 186

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            A     L   PL   GRPE++AGAV+FL S DA +++G T+ V GG
Sbjct: 187 PAYRLLMLDGTPLPGPGRPEDVAGAVSFLCSPDARFVSGVTLNVDGG 233


>UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Sinorhizobium medicae
           WSM419
          Length = 251

 Score =  115 bits (276), Expect = 1e-24
 Identities = 69/229 (30%), Positives = 106/229 (46%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVI--CSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
           AIA  L   G  V I    R++  +      +   G  V  V   V++    R + +   
Sbjct: 20  AIAIGLAERGYDVAINDIERQKDVLAGVATEIEELGRRVITVCADVSSKAEVRAMAKAVG 79

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
             FG +D +            +   DE+ WD + DVN K ++L+ +   P +  R  G I
Sbjct: 80  DAFGHLDAVVNNAGILISGD-VEGLDEEHWDSVMDVNAKGTFLVVQAVLPMMKARRYGRI 138

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           V I+SI           Y  SK  ++G T+ +A E   + I  NCV PGI++T       
Sbjct: 139 VNIASIGGKHGAPEQAHYSASKAAVMGFTRVLAQEVGVDGITANCVCPGIILTDMGRVNL 198

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +  A  +       ++R G PE++ GAVAF ASDDA+++TG+T+ V GG
Sbjct: 199 DDPAVKKSWQDKTAMRRIGDPEDVVGAVAFFASDDAAFVTGQTLNVDGG 247


>UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN)
           REDUCTASE; n=6; Brucellaceae|Rep:
           3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella
           melitensis
          Length = 249

 Score =  114 bits (275), Expect = 2e-24
 Identities = 73/230 (31%), Positives = 113/230 (49%), Gaps = 4/230 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A+R  +EGA VV+       V   +  + S GI+++     V+      R+   A  +F
Sbjct: 22  MARRFAAEGARVVLADVNVKRVEDGLADISSNGISIQA---DVSRKNDMERVARTAFEEF 78

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +DI+            + D DE  +D I  VN+K+ +   +   P +  +GGG I+  
Sbjct: 79  GRIDIMVNNAGFTHRNMPLTDVDEHNFDLIVAVNMKALYYSTQLVVPIMEHQGGGVIINT 138

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAP----GIVVTKFASAI 233
           +S     P + L  Y  SK+ ++  TKA+A E    NIRVNC+ P    G  +  F +  
Sbjct: 139 ASATGLHPRKGLTWYCASKSWVVSATKAMALELAERNIRVNCLCPAESDGEGLKMFLAED 198

Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           T     A K  S +PL RF  P+++A A  +LASDDAS +TG  + + GG
Sbjct: 199 TPEARAALK--STIPLGRFSTPKDVAEAALWLASDDASMVTGVALGIDGG 246


>UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=36;
           Proteobacteria|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Burkholderia mallei
           (Pseudomonas mallei)
          Length = 269

 Score =  114 bits (275), Expect = 2e-24
 Identities = 74/233 (31%), Positives = 115/233 (49%), Gaps = 6/233 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE--GITVEGVVCHVANHEHRRRLFEVAT 590
           AIA+    EGA+V I     +   ++  ++  +  G  V  V   VA  E          
Sbjct: 31  AIARAFVREGAAVAIAELDAALAEESADAIARDTAGARVLAVPTDVARAESVAAALARTE 90

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
             FG +D+L            +  TDE  W + F +++   W   + A P +V+RG GSI
Sbjct: 91  RAFGPLDVLVNNAGVNVFGDPLALTDED-WRRCFAIDLDGVWNGCRAALPGMVERGRGSI 149

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA---- 242
           V I+S  A++       Y V+K  +LGLT+A+  E    N+RVN +APG + T+      
Sbjct: 150 VNIASTHAFKIIPGCFPYPVAKHGVLGLTRALGIEYAPRNVRVNAIAPGYIETQLTHDWW 209

Query: 241 SAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           SA  + +A   ++L+  P+KR GRP+E+A    FLASD+A +I    + + GG
Sbjct: 210 SAQPDPQAARRETLALQPMKRIGRPDEVAMTAVFLASDEAPFINASCITIDGG 262


>UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholderia
           xenovorans LB400|Rep: Putative dehydrogenase -
           Burkholderia xenovorans (strain LB400)
          Length = 281

 Score =  114 bits (275), Expect = 2e-24
 Identities = 72/226 (31%), Positives = 104/226 (46%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IAKRL   GASV +       +      L   G TV  V C+V +    R       S F
Sbjct: 25  IAKRLAGLGASVALLEPGIERLVSLASELTDSGATVLNVACNVTDAASTRYAAAQVLSSF 84

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +D+L           ++     + WD+   VN+  + L        +++ G GSIV I
Sbjct: 85  GRIDVLVNNAGVLARPSALESISLEDWDRSLAVNLTGALLCTASFGAAMLEAGAGSIVNI 144

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSE 221
           +SIAAY P   + AY VSK  LL LT+  A E     IR N V+PG + T  +     + 
Sbjct: 145 ASIAAYSPNTSV-AYSVSKAGLLALTRHTAVEWAPRGIRANSVSPGFIRTPLSEVHYANP 203

Query: 220 AGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              +      P++R G  +++A  V FLAS  +++I GE +V  GG
Sbjct: 204 DLLQLRTQATPVRRLGTVDDVAAIVGFLASPASAFINGEDIVADGG 249


>UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 246

 Score =  114 bits (275), Expect = 2e-24
 Identities = 66/227 (29%), Positives = 112/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA +L +EGA+VV+         +   +L    I   G+   V +      + +   + 
Sbjct: 21  AIATKLAAEGATVVVTDVDHQAAKETAAALDHGAI---GLHADVTDRTSVDAMVDEVVAT 77

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D+L            + D++ + WD+I  +N+      +K+  P +  +G GS+V 
Sbjct: 78  FGRIDVLVNNAGWDKGEAFV-DSEPETWDRIIGINLYGVLNTSKKVLPIMAAQGSGSVVN 136

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I S A    +     Y  +K  ++  +KA A E     + VNCV PG   T   +++   
Sbjct: 137 IGSDAGRVGSSGEAVYSAAKGGVIAFSKATAREMARSQVNVNCVCPGPTDTALFASMGGD 196

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +   E  +  +P +R G+PE++A  VAFLASD+A ++TG+TV V+GG
Sbjct: 197 KL-REALVKAIPFRRLGQPEDLANVVAFLASDEAGFVTGQTVSVSGG 242


>UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
           dehydrogenase/reductase SDR - Caldivirga maquilingensis
           IC-167
          Length = 248

 Score =  114 bits (275), Expect = 2e-24
 Identities = 76/229 (33%), Positives = 117/229 (51%), Gaps = 3/229 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVIC--SRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           IA RL  +GA VV    + KE+ V + V+ L  +G+ +      V + +    +      
Sbjct: 22  IALRLARDGAIVVATDITGKENEVAEEVRKLGGQGMALR---LDVTDGKMAEEVARTVFD 78

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           K+G +DIL            +  T    W ++ +VN+   + + +   P +VK+  G I+
Sbjct: 79  KYGHIDILVNNAGIYPFKPFMEMTFND-WYRVINVNLNGVFNVTRAVVPYMVKQKNGRII 137

Query: 406 FISSIA-AYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
            I+SIA A      L  Y  SK  ++G T+A+A E     I VN +APG + T    A T
Sbjct: 138 NIASIAGAVMGFMGLTHYSASKAGIVGFTRALALELARYGITVNAIAPGAINTP--GAAT 195

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            SE      ++ +P+ + G PE+IA AVA+LASD+ASYITG  +V+ GG
Sbjct: 196 GSEEQVRMMINAIPMGKLGTPEDIASAVAYLASDEASYITGALIVIDGG 244


>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
           n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
           TM_0325 - Thermotoga maritima
          Length = 251

 Score =  114 bits (275), Expect = 2e-24
 Identities = 79/232 (34%), Positives = 115/232 (49%), Gaps = 4/232 (1%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A      GA V I    E    + V+ ++S G     +   VA  +   ++ +     FG
Sbjct: 22  AVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIFGDVA--KDAEQIVKKTVETFG 79

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
            +DIL            I +T E+ +DK   VNVK  +LL+K A  ++ K+GGG IV +S
Sbjct: 80  RLDILVNNAGIVPYGN-IEETSEEDFDKTMAVNVKGPFLLSKYAVEQMKKQGGGVIVNVS 138

Query: 397 SIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTK----FASAIT 230
           S A          Y VSK  LLGLT+++A + V   IRVN V PG   ++       A  
Sbjct: 139 SEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVNAVCPGTTQSEGLMARVKASP 198

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           N E   +K  S +P+KR G+ EEIA A+ F A D+A ++TG  + + GG+ A
Sbjct: 199 NPEELLKKMTSRIPMKRLGKEEEIAFAILFAACDEAGFMTGSIINIDGGSTA 250


>UniRef50_Q3WH17 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=5; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Frankia sp.
           EAN1pec
          Length = 257

 Score =  114 bits (274), Expect = 3e-24
 Identities = 78/235 (33%), Positives = 107/235 (45%), Gaps = 6/235 (2%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           AKRL  E A VV+     +     V+ +   G +   V   +A+      + +    KFG
Sbjct: 23  AKRLAEESAKVVVGDINLAGAQSTVRKINEAGGSAVAVHFDLADEHSVNEMVDTTLEKFG 82

Query: 577 GVDILXXXXXXXX-----XXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
            V  L                S+LDTD  VW +  DVNV       +   P L+  GGG 
Sbjct: 83  AVHGLFNVGADLSPGNLGRDKSVLDTDLDVWHRTLDVNVVGFVRTIRAVLPHLLANGGGG 142

Query: 412 IVFISSIAAYQPTEPLG-AYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA 236
           IV  SS AA    + L  AY  SK+ +  LT+ +A       +R N V PG+V+ +    
Sbjct: 143 IVNTSSGAAVSAGDRLRPAYAASKSAVNALTRHVAGNWGSRGVRCNGVMPGLVMGE-TQE 201

Query: 235 ITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           I N  A  E+ L  VP  R GRP ++A  V+FL SDDA +I G+   + GGA  R
Sbjct: 202 IQNDVALQERFLKEVPTTRLGRPSDLAAVVSFLLSDDAEWINGQVWAIDGGANMR 256


>UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4;
           Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase
           - Clostridium perfringens (strain SM101 / Type A)
          Length = 253

 Score =  114 bits (274), Expect = 3e-24
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 2/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLR--SEGITVEGVVCHVANHEHRRRLFEVAT 590
           A  K+    GA V +C  ++  V KA++ L   +      G   ++ +    + + +   
Sbjct: 25  ATVKKFLDHGAKVALCGSRKETVDKALEELNYINPNYDAIGFYPNLLDSNEVKEMVDKVL 84

Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
            K+G +DIL               +DE  + KI D+NVK+ +   K     +  +  G I
Sbjct: 85  EKWGTIDILINNAGVSDNKSIYTQSDED-FSKIIDINVKAIFNCTKAVSEIMKNKKYGVI 143

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           +  SS+ +    +    Y  SK  + GLTK++A E   + IRVN VAPGI+ T   +A+ 
Sbjct: 144 LNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLARELGRDGIRVNAVAPGIIATDMVAAL- 202

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
             +   ++   NVPL R G PE+IA A  FLASD ASYI+GE + V G
Sbjct: 203 -DKKLVDQIAQNVPLGRVGEPEDIANAFLFLASDMASYISGEILSVDG 249


>UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Methylobacterium
           extorquens PA1
          Length = 282

 Score =  114 bits (274), Expect = 3e-24
 Identities = 67/227 (29%), Positives = 108/227 (47%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A     EGA V I  R E  + +    +   G  V  + C V+  E           +
Sbjct: 55  AAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGAVIAIRCDVSLPEDVAAAVARTVER 114

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D              + +     WD+I D+N++ +++  K    +++++GGG +V 
Sbjct: 115 FGRLDCAFNNAGVENKAAPVHEIALDEWDRILDINLRGTFVCMKHEIAQMLRQGGGVVVN 174

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            SS A  +      +Y  SK  L+GLTK+ A +    NIRVN V PG + T      T  
Sbjct: 175 TSSGAGIRGVAGGASYAASKHALIGLTKSAALDYAKANIRVNAVLPGNIETPMMERFTGG 234

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +   +K++   P+ R G+PEEIA AV ++ SD  +++TG ++ V GG
Sbjct: 235 D--IQKAIDLEPVGRLGKPEEIAEAVLWMCSDLGAFVTGASISVDGG 279


>UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Dehalococcoides|Rep: Short-chain
           dehydrogenase/reductase SDR - Dehalococcoides sp. BAV1
          Length = 265

 Score =  114 bits (274), Expect = 3e-24
 Identities = 75/236 (31%), Positives = 115/236 (48%), Gaps = 9/236 (3%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           I+ RL   GAS++I         K V  +++ G     +   V+N    +++ +     F
Sbjct: 28  ISMRLAEAGASIMIPDLNLEVAQKTVAEIKALGGKATAIQADVSNINDTQKVIDATLKAF 87

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVF 404
           G +DI+           +I D  E +WDK   +N+K     ++ A   ++  + GG I+ 
Sbjct: 88  GDLDIMVNNAGIYRFMPAI-DMTEAMWDKTLGINLKGLMFFSQAAAKAMMAAKHGGKIIN 146

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I+SI  ++PT  L  Y  SK  ++ LTKA+A E     I VN VAPG + T  ASA+  S
Sbjct: 147 IASIDGFRPTGNLAHYDASKGGVIMLTKAMAQEWAPHGILVNAVAPGGINTPGASALMPS 206

Query: 223 EAGAEKSL--------SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
            + + + L        + +PLKR G P++I   V FL S  A YI G  +V  GGA
Sbjct: 207 GSMSAEQLMELSKSFVAKLPLKRMGEPDDIGKVVLFLTSAAADYIVGSVIVADGGA 262


>UniRef50_A4CKB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=2;
           Flavobacteriales|Rep: 2-deoxy-D-gluconate
           3-dehydrogenase - Robiginitalea biformata HTCC2501
          Length = 257

 Score =  114 bits (274), Expect = 3e-24
 Identities = 70/232 (30%), Positives = 120/232 (51%), Gaps = 1/232 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+ + L   GA  VI    E  V +     R++G+ V+ +   V+     R  ++ A  K
Sbjct: 28  AMVEALAQAGAQTVIIDFDE-RVFELCDKFRADGLQVDPIRADVSEISQVRESYKEALEK 86

Query: 583 FGG-VDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
            GG +DIL           S  +  E+ W K+  +N+ +++   K A  +++K GGG I+
Sbjct: 87  LGGTIDILVNSAGIQRRYPSE-EFPEEEWSKVIAINLDATFYYCKYAANDMIKNGGGKII 145

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            I+S+ ++     + AY  SK  +  LTKA++N+   + I VN +APG + T+  +A+  
Sbjct: 146 NIASLMSFLGGITIPAYAASKGGVAQLTKALSNDWAAKGICVNAIAPGYMDTQLNTALIA 205

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
            +   ++ +  VP+KR+G  E++ G   FL+S  + YITG  + V GG  AR
Sbjct: 206 DKKRTDEVMLRVPMKRWGDGEDLKGLTVFLSSAASDYITGCVIPVDGGYLAR 257


>UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Comamonas testosteroni KF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Comamonas testosteroni
           KF-1
          Length = 263

 Score =  114 bits (274), Expect = 3e-24
 Identities = 70/227 (30%), Positives = 113/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+  RL + GASVV    K  +  +A  SL           C + +      +       
Sbjct: 33  AMVARLAAMGASVVAADMKAPDNAQAALSL----------ACDITDEAAIEAMAAKVKDT 82

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG  DIL            + +    +WDK+  VN++ S+L AK     ++++  G+IV 
Sbjct: 83  FGRCDILVNNAGVMAPVVPLEELPVAMWDKVMSVNLRGSFLCAKYLVRMMLEQKRGAIVN 142

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++SI A  P + +G YG SK  +LGLT  +A E     +R N ++PG++ T  +     +
Sbjct: 143 LASIGARVPND-IGPYGPSKAGVLGLTHQMAVEWGPRGVRTNSISPGMIRTPMSEHFYQN 201

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E   +  +  VP+ R GRPE+IA A+ F+ SD ASY+ G+ +++ GG
Sbjct: 202 EKLHQGRIKVVPVGRIGRPEDIADAMGFIVSDAASYMNGQDIIIDGG 248


>UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
           dehydrogenase/reductase SDR - Caldivirga maquilingensis
           IC-167
          Length = 278

 Score =  114 bits (274), Expect = 3e-24
 Identities = 76/237 (32%), Positives = 120/237 (50%), Gaps = 7/237 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+  G  GA V++   +      A+  LR  GI     +  VA+  +  +L ++   +
Sbjct: 26  AIAEEFGKAGARVIVNGVRREVAENALNYLRGRGIEPILFLGDVADRGNVVKLRDLIEGE 85

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +D+L              D D + W ++ +VN+ + ++LA+E  P ++K  G  I+ 
Sbjct: 86  CGRLDVLVNNASIEVDKP-FEDYDYETWRRLIEVNLDAYYMLARELLPLIIKGEGKVIIN 144

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASA-ITN 227
           ISS+   +     GAY V+K   +GLT+ +A +     +RV  VAPG + T       +N
Sbjct: 145 ISSVQGVECEPTTGAYSVTKAAEIGLTRVMALDLAKYGVRVITVAPGAIDTPLNRVKSSN 204

Query: 226 SEAGA--EKSLS----NVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            + G   E + S     +P+ RFG+PEE+A  V FL+S  ASY+TG TV V GG  A
Sbjct: 205 LDPGGSWEHAYSVISEAIPMGRFGKPEEVANVVLFLSSRAASYMTGTTVFVDGGLTA 261


>UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep:
           Gll2858 protein - Gloeobacter violaceus
          Length = 268

 Score =  113 bits (273), Expect = 3e-24
 Identities = 72/228 (31%), Positives = 113/228 (49%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A  L   GA VV  +R+     + V+++R+EG     V   V +  +  RL   A + 
Sbjct: 38  ATALELARRGAKVVASARRVGPTLELVEAIRAEGHEATFVQADVTDEAYVERLVAEAIAT 97

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +G +DI             +L+  ++ +D +FD NV+S +   K     ++  GGG IV 
Sbjct: 98  YGKLDIAFNNAGTEGVFAPLLEQTKETYDLVFDANVRSVFYSMKHQAQAMLCAGGGVIVN 157

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +S+      E    Y  +K  +LG+TK+ A E     +RVN + PGI+ T F   I  S
Sbjct: 158 NASMGGVIGFENAALYIATKHAVLGMTKSAALEWYRRGVRVNAICPGIIDTPFQDRIWPS 217

Query: 223 EAGAEKSLSNVPLK-RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              A+ S +N  +  R G  EE+A  VAFL S+DAS+++G  ++  GG
Sbjct: 218 -TEAKNSFANATVAGRAGTAEEMAKVVAFLVSEDASFVSGHGLLADGG 264


>UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Nostocaceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Anabaena variabilis
           (strain ATCC 29413 / PCC 7937)
          Length = 294

 Score =  113 bits (273), Expect = 3e-24
 Identities = 77/240 (32%), Positives = 111/240 (46%), Gaps = 12/240 (5%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKES---NVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVA 593
           A+AK L SEG +V I SR +    N   A+QSL + G  V  +   +   E   R+    
Sbjct: 52  AVAKALYSEGVNVAIASRSQERLENAVSAIQSLPTPGAKVIAISADLTQAESVDRVVSST 111

Query: 592 TSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS 413
            ++FG +DIL            +  TD+   D  +++ +       +   P L  +G G 
Sbjct: 112 LAQFGQIDILINNAGSARAGSFLDSTDDLFLDA-WNLKLLGYIRFVRAVVPHLRSQGDGR 170

Query: 412 IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
           IV I   A   P     A G S   LL  TK I+ E    NIR+N ++PG   T+ A  +
Sbjct: 171 IVNIIGGAGRTPRPNFLAGGTSNAALLNFTKGISKELAEYNIRINAISPGATATERAETL 230

Query: 232 TNSEAGAE---------KSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
               A A          +SL ++PLKR  +P+EIA    FL SD A+ ITG  ++V GG+
Sbjct: 231 ARQNAQARGITVEQAKAESLQSIPLKRIAQPDEIAALALFLVSDLAASITGTEIIVDGGS 290


>UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like
           protein; n=1; Hahella chejuensis KCTC 2396|Rep:
           Short-chain alcohol dehydrogenase-like protein - Hahella
           chejuensis (strain KCTC 2396)
          Length = 251

 Score =  113 bits (273), Expect = 3e-24
 Identities = 71/231 (30%), Positives = 110/231 (47%), Gaps = 2/231 (0%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A +L + GA V + +R+       V+ +   G     +   V++    +         FG
Sbjct: 22  AIKLANYGAKVAVIARRSRESEDTVRHITEAGGQAISIPADVSSESDIKNALAQIIETFG 81

Query: 577 GVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFIS 398
            +D              + +  EQ WD++F +N K +WL  K   P L+    G+IV +S
Sbjct: 82  KLDGAFNNAGAAEPVGPLTELSEQEWDRVFSINTKGAWLCMKHQIPALLSNKSGAIVNMS 141

Query: 397 SIAAYQPT-EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTK-FASAITNS 224
           SI     T   L AY  SK  ++GLTKA + E    NIR+N + PG + T     A++N 
Sbjct: 142 SIYGLVGTGMGLAAYVASKHAIIGLTKAASLEYAARNIRINAICPGWIPTPGNEQALSNP 201

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           E  A  + S  P  R G  +E+A AV ++ SD ASY+ G+T+ + GG  A+
Sbjct: 202 EVMA-FAQSLHPQGRLGTQQEVAEAVCWMLSDSASYLNGQTISIDGGYTAQ 251


>UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Paracoccus
           denitrificans (strain Pd 1222)
          Length = 253

 Score =  113 bits (273), Expect = 3e-24
 Identities = 77/234 (32%), Positives = 115/234 (49%), Gaps = 6/234 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATS 587
           A AK    EGA VV+       +G A + + +E G         V+  E  + + +   +
Sbjct: 22  ATAKLFIEEGARVVVADY----LGDAAEQVAAELGENARAFTVDVSKAEACKAMVDFTVA 77

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           +FGG+D+L            +   DE  W  I DVN+   +L +K A PEL KRGGG+IV
Sbjct: 78  EFGGLDVLVNNAGRGSLGT-VETQDENDWRSIIDVNLTGVYLCSKYAVPELRKRGGGAIV 136

Query: 406 -FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV----VTKFA 242
              S+IA         AY  +K  +  LT+A+A +   +NIRVN VAPG++      K  
Sbjct: 137 NTASNIAMAMAIRDRAAYVAAKGGVASLTRAMALDFAADNIRVNSVAPGVIWSNYYNKML 196

Query: 241 SAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
           + + + EA      +  P   +G P++IA A+ +LASD A +  G  + V GGA
Sbjct: 197 TQVPDPEAFKAGLRARAPSNSWGEPDDIASAIVWLASDRARFAVGTMLTVDGGA 250


>UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2;
           Bacteria|Rep: Cyclopentanol dehydrogenase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 355

 Score =  113 bits (273), Expect = 3e-24
 Identities = 80/227 (35%), Positives = 103/227 (45%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+     GA V IC   E    K    LR  G+  +     V + E   R      + 
Sbjct: 116 AEARLFAQHGAHVYICDVLEEEGEKLAAELRGSGLQADFRFLDVTDAEQWSRTVAHIDAG 175

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +D+L            + DT  + WD+I  VN K   L  +   P + + G GSI+ 
Sbjct: 176 AGRLDVLINNAGINVRHQ-LTDTTSEEWDRIVAVNTKGQMLGMQACAPLMKRSGNGSIIN 234

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           I S A      P+ AY  SK  + GLTKA A E     IRVN + PG+V T    A   S
Sbjct: 235 IGSTAGIMG-HPVAAYSASKWAVRGLTKAAAMELASSGIRVNAMHPGVVETPMVDA--GS 291

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              AE   S  PL R  +P E+A A  FLASD+AS+ITG  + V GG
Sbjct: 292 RVFAELR-SLTPLGRAAQPSEMASAALFLASDEASFITGIDLAVDGG 337


>UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=14; Clostridia|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Clostridium
           tetani
          Length = 249

 Score =  113 bits (272), Expect = 5e-24
 Identities = 70/227 (30%), Positives = 111/227 (48%), Gaps = 1/227 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKE-SNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           IA  L  +GA V++  RK+     +  +++   G     + C V+++E  + + E     
Sbjct: 24  IAIELADKGACVIVNYRKDLKGAEETKKTIEERGGYCRIIKCDVSSYEDTKLMIEKIIRD 83

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DIL            I D +E+ WD I + N+K  +  ++   P ++    G I+ 
Sbjct: 84  FGKIDILINNAGISKIGLFI-DMEEEDWDNIINTNLKGVFNCSRNVLPYMIGEKNGVIIN 142

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS+           Y  SK  +   TKA+A E    NIRVN ++PG++ T     ++  
Sbjct: 143 ISSMWGSVGASCEVIYSASKGGVDSFTKALAKEVGPSNIRVNAISPGVINTSMNEWMSCE 202

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E  + K    +PL RFG  E+I  AV FL SD+A YITG+ + + GG
Sbjct: 203 EKDSLKD--EIPLCRFGECEDIGKAVVFLCSDNAKYITGQILTIDGG 247


>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family; n=1; Photobacterium
           profundum|Rep: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family - Photobacterium
           profundum (Photobacterium sp. (strain SS9))
          Length = 255

 Score =  113 bits (272), Expect = 5e-24
 Identities = 64/228 (28%), Positives = 114/228 (50%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+    +GAS+V+ +R E+      + L ++  T+  +   +       ++FE   ++
Sbjct: 24  ATARLFSQQGASLVLVARNENKGQMLAEELNAQYPTLF-IKADITQANQVDQVFEQTMAE 82

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FGG+D              I +T +++W++I + N+  +W +       + K+G G+IV 
Sbjct: 83  FGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLNRQLSIMSKQGHGTIVN 142

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++SI +        AY  S+  +LGLT++ A E   + +RVN VAPG + T      T  
Sbjct: 143 MASICSVLARPNRAAYNTSRHAVLGLTRSAAVEYAKQGVRVNAVAPGAIDTPIFERSTQK 202

Query: 223 EAG-AEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           +     K     P+ R G+P E+A A  +L SD +S++ G T++V GG
Sbjct: 203 DPQLIAKYHQAHPIGRIGQPREVAEAALWLCSDLSSFVVGHTLMVDGG 250


>UniRef50_Q53W82 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=2;
           Thermus thermophilus|Rep: 2-deoxy-D-gluconate
           3-dehydrogenase - Thermus thermophilus (strain HB8 /
           ATCC 27634 / DSM 579)
          Length = 239

 Score =  113 bits (272), Expect = 5e-24
 Identities = 73/229 (31%), Positives = 116/229 (50%), Gaps = 2/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AIA+ L + G  V I SR   N  +A QSL +  +  +         +  + L + A   
Sbjct: 17  AIAEALVARGYRVAIASR---NPEEAAQSLGAVPLPTD------LEKDDPKGLVKRALEA 67

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            GG+ +L           + L+   + W ++  +++  ++LLA+ A P + + G G ++F
Sbjct: 68  LGGLHVLVHAAAVNVRKPA-LELSYEEWRRVLYLHLDVAFLLAQAAAPHMAEAGWGRVLF 126

Query: 403 ISSIAAYQP--TEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           I S+  +      P+ AY  +KT LLGLT+A+A E     IRVN + PG V T+F   + 
Sbjct: 127 IGSVTTFTAGGPVPIPAYTTAKTALLGLTRALAKEWARLGIRVNLLCPGYVETEFTLPLR 186

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            +    E   + +P+ R+ RPEEIA   A L  D+A Y+TG+ V V GG
Sbjct: 187 QNPELYEPITARIPMGRWARPEEIARVAAVLCGDEAEYLTGQAVAVDGG 235


>UniRef50_Q3W9H8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 286

 Score =  113 bits (272), Expect = 5e-24
 Identities = 74/229 (32%), Positives = 116/229 (50%), Gaps = 2/229 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRS-EGI-TVEGVVCHVANHEHRRRLFEVATS 587
           IA+   +EGA VVIC+RK   V  A + L + EG   V G+V +    EH  R    A  
Sbjct: 52  IARAFRAEGAHVVICARKAEGVAAAAKELLAGEGDGEVLGLVANAGEPEHAERTVTAALE 111

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           + G +DIL            ++D D    +K   VN        + A    +   GGS++
Sbjct: 112 RLGRLDILVNNAATNPYMGPLVDIDLPRAEKTTKVNQIGMLAWIRYAVRGWMVEHGGSVI 171

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            I+S+        +G Y  +K  +L +T+ +A E +   +RVN +APG++ T+ A A+  
Sbjct: 172 NIASVGGLIVDPGIGFYNATKAAILLMTRQLAYE-LGPAVRVNALAPGVIKTELARAVW- 229

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
            E       + +PL+R G  +++A A  F ASD +S+ITG+T+V+ GGA
Sbjct: 230 -EVREPVLTAQLPLRRLGTVQDVANAAVFFASDASSWITGQTLVLDGGA 277


>UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma
           proteobacterium HTCC2207|Rep: Short chain dehydrogenase
           - gamma proteobacterium HTCC2207
          Length = 249

 Score =  113 bits (272), Expect = 5e-24
 Identities = 66/227 (29%), Positives = 109/227 (48%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+  G+ GA +VI    +  + KAV+ L   G  V G++  V++      +     ++
Sbjct: 22  ACAQAFGAAGAKLVITDISKEPLDKAVEELEQAGAEVLGLINDVSDSADVSAMMSAIVAR 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +DI               +  E  +D++  VN+K  WL  +    +++++GGG IV 
Sbjct: 82  FGRLDIAVNNAGTATPLQEFHEVGEAEFDRVMAVNLKGVWLCMQAEIRQMLEQGGGRIVN 141

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ++S  +         Y  SK  + GLT+ +A E    +IR+N + PG V T    ++ + 
Sbjct: 142 MASATSRNTYPNASPYVTSKFAVAGLTRTVAVEYADRDIRINAICPGNVATPLVVSLVDD 201

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                   +   +KR G PEE+A  V FLASD +S+ TG  + V GG
Sbjct: 202 ---LSVLATKHAIKRLGTPEEVANGVMFLASDLSSFSTGSLLEVDGG 245


>UniRef50_Q1NCY5 Cluster: Dehydrogenase; n=1; Sphingomonas sp.
           SKA58|Rep: Dehydrogenase - Sphingomonas sp. SKA58
          Length = 258

 Score =  113 bits (272), Expect = 5e-24
 Identities = 74/233 (31%), Positives = 116/233 (49%), Gaps = 5/233 (2%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFG 578
           A+RLG EGA VVI  R  +   +    + S G  +  V     +    ++L   A   FG
Sbjct: 23  AERLGQEGAKVVIADRNIAGAEQVAHGI-SNGQAL-AVQFDATDEGSIQKLIATAKDHFG 80

Query: 577 GVDILXXXXXXXXXX----XSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSI 410
            +DIL               ++LDT  +  D  + +N++S ++  K A P ++ +GGGSI
Sbjct: 81  RIDILHNNVAMTAEAWSRDTNLLDTTVETLDLSYAINLRSMFIACKAALPIMIDQGGGSI 140

Query: 409 VFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAIT 230
           + +SS +       L AYG +K  ++ LTK +A +    N+R NC+ PG+++T+    I 
Sbjct: 141 INMSSGSGEAGAPTLIAYGTTKGGVITLTKYLAVQYGRANVRSNCILPGLIMTE---QIK 197

Query: 229 NSEAGAEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
            +   A++      P  R G P +IAG V F ASDDA ++ G+ V   GG  A
Sbjct: 198 QNVPDADRIYRRTTPFDRAGTPADIAGMVVFFASDDAVFVNGQIVHCDGGGSA 250


>UniRef50_Q1CYK0 Cluster: Putative 3-oxoacyl-(Acyl-carrier-protein)
           reductase; n=1; Myxococcus xanthus DK 1622|Rep: Putative
           3-oxoacyl-(Acyl-carrier-protein) reductase - Myxococcus
           xanthus (strain DK 1622)
          Length = 258

 Score =  113 bits (272), Expect = 5e-24
 Identities = 68/228 (29%), Positives = 113/228 (49%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGK-AVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
           AIA    +EGA +V+     +   + A   + ++G     V   VA+ +   +L E A S
Sbjct: 29  AIALAFAAEGADIVLNYGSNAEAARQAAAEVEAQGRRCVLVPGSVASPDVPGQLREAALS 88

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
            FG +D+L            ++      W +  DVN+  +    +   P ++++G G+I+
Sbjct: 89  HFGRIDVLVNNAGISRDGHLMM-LQAAAWRETVDVNLYGALACCQAVIPTMMQQGRGAII 147

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            +SS A  +       Y  +K  L+GLT+A+A E     IRVNCVAPG V T+  + + N
Sbjct: 148 NMSSSAGIRGRAGQVPYAATKGALIGLTQALAGELGPHGIRVNCVAPGFVETEMVAGLMN 207

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                E  +   P++R G  E++A A  FLAS +++Y+ G+ + V GG
Sbjct: 208 RPGVREGFIQATPIRRLGTVEDVANATLFLASPESAYVVGDVLRVNGG 255


>UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2;
           Frankia|Rep: Putative dehydrogenase/reductase - Frankia
           alni (strain ACN14a)
          Length = 295

 Score =  113 bits (272), Expect = 5e-24
 Identities = 70/230 (30%), Positives = 111/230 (48%), Gaps = 1/230 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A+   + GA V +  R ++ +   V+SL   G  + G+   V       R+       F
Sbjct: 67  VAEAFLAAGARVAVVGRDKAKMDAVVESLAPLGEII-GIQADVTVVAEAARIVSATVDHF 125

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG-GSIVF 404
           GG+DIL            +LD  E  +D  FD+NVK ++  A+ A   LV +G  G I+ 
Sbjct: 126 GGLDILATVAGVFEGAP-LLDATEADYDIQFDLNVKGTYFCAQAAARHLVDQGRRGKIIT 184

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           + S+A  +    +  YG +K  +  LT+ +A E     I VNCV PG +     + + + 
Sbjct: 185 VGSVAGLRAFPGVSVYGATKAAVGFLTQVLAGELAPHGINVNCVVPGSIDMP-TNKLLSP 243

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
              AE S +  P +R G P ++A A  +LASD A ++ G ++VV GG  A
Sbjct: 244 PGAAEASAAGTPARRNGLPVDVAAAAVYLASDSADFVHGTSLVVDGGVAA 293


>UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MWYL1
          Length = 258

 Score =  113 bits (272), Expect = 5e-24
 Identities = 70/228 (30%), Positives = 112/228 (49%), Gaps = 3/228 (1%)
 Frame = -3

Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSKF 581
           AK   + GAS+V+    +S++    ++L ++  IT+      V N        + A S F
Sbjct: 28  AKAFAACGASLVLIDFNQSSLESLKETLLNQYSITISTYAVDVTNEAAIVDCAQNAMSTF 87

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +D+L           +  D   + W+K+ DVN+  ++   +    +++K+G GSI+ +
Sbjct: 88  GQIDVLVNSAGIALLHSAA-DISSEDWNKVLDVNINGTFWACRAFAAQMMKQGSGSIINL 146

Query: 400 SSIAAYQPTEP--LGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            S++     +P    +Y VSK  +  LTKA+A E   + IRVN +APG V T     +  
Sbjct: 147 GSMSGSVINQPQFASSYMVSKAAVHQLTKALAVEWAQQGIRVNALAPGYVATDMTLEMRA 206

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                 K L   PL R G P EIA  + FL SD ++Y+TG  V + GG
Sbjct: 207 QPELFYKWLEMTPLGRLGSPSEIAAMILFLGSDASTYLTGSVVAIDGG 254


>UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=3; Planctomycetaceae|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Blastopirellula marina DSM 3645
          Length = 256

 Score =  113 bits (272), Expect = 5e-24
 Identities = 59/227 (25%), Positives = 108/227 (47%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           +IA  + S GA V + +R    +   V  + + G   +   C V   E    + +    K
Sbjct: 30  SIATAMASRGAKVAVVARNAEKLADTVAIIEAAGGVAQAYSCDVTKRESVEAVVDAVMEK 89

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           +  +D+L             + TD++ WD + + N++  +L  + A  ++++   G I+ 
Sbjct: 90  WEKLDVLVNNAGVTRDNLLPVMTDDE-WDNVIETNLRGMFLFTRAASKQMMRARFGRIIN 148

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           ISS++          Y  SK  ++G T++++ E     + VN + PG + +    A+   
Sbjct: 149 ISSVSGLMGNPGQTNYSASKAGMIGFTRSLSRELGKRKVTVNAICPGFIESDMTKAL--G 206

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            A  ++    +P +R G+PEEIA  V FLAS  A+YITG+ + + GG
Sbjct: 207 PAVMDEVKKRIPAQRMGKPEEIADGVLFLASPQAAYITGQVLTIDGG 253


>UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Bacillus halodurans
          Length = 246

 Score =  113 bits (271), Expect = 6e-24
 Identities = 70/227 (30%), Positives = 105/227 (46%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK+   EGA V++C  +E  V K V  ++  G    G V  V   +  + +      +
Sbjct: 20  ATAKKFAREGAKVIVCDVREEEVAKTVAEIQDGGGEALGSVVDVTQRKDVKNVINQVIER 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           F  +D++               TD Q WD + DVN+K  +++ +E    + ++  G I+ 
Sbjct: 80  FETLDVVVNNAGITADAQLTNMTDAQ-WDDVIDVNLKGVFIVTQEVTTIMKEQKRGVILN 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            SS+           Y  SK  + G+TK  A E    NIRVN VAPG ++T     +   
Sbjct: 139 ASSVVGSYGNFGQTNYAASKWGVNGMTKTWAKELGRYNIRVNAVAPGFILTPMTEKMP-- 196

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E   +       L R G  EE+A   AFLASD+AS+ITG  + + GG
Sbjct: 197 EKVLKVMEEKAVLNRLGTVEEVANGYAFLASDEASFITGTILAIDGG 243


>UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;
           n=6; Bacteria|Rep: 2-keto-3-deoxygluconate
           oxidoreductase - Erwinia carotovora subsp. atroseptica
           (Pectobacterium atrosepticum)
          Length = 253

 Score =  113 bits (271), Expect = 6e-24
 Identities = 64/206 (31%), Positives = 112/206 (54%), Gaps = 1/206 (0%)
 Frame = -3

Query: 685 VQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQ 506
           V +L    +++   + +VA H     L E A ++FG VDIL           +I +  E+
Sbjct: 52  VTALGRRFLSLTADMSNVAGHAE---LVEKAVAEFGHVDILVNNAGIIRREDAI-EFSEK 107

Query: 505 VWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLG 329
            WD + ++N+KS + +++    + +K+G GG I+ I+S+ ++Q    + +Y  SK+ ++G
Sbjct: 108 NWDDVMNLNIKSVFFMSQAVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMG 167

Query: 328 LTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGA 149
           +T+ +ANE     I VN +APG + T     +   E  +++ L  +P  R+G P+++ G 
Sbjct: 168 VTRLLANEWAKHGINVNAIAPGYMATNNTQQLRADEDRSKEILDRIPAGRWGLPQDLMGP 227

Query: 148 VAFLASDDASYITGETVVVAGGAPAR 71
             FLAS  + YI G T+ V GG  AR
Sbjct: 228 SVFLASSASDYINGYTIAVDGGWLAR 253


>UniRef50_Q1NH63 Cluster: Dehydrogenase; n=1; Sphingomonas sp.
           SKA58|Rep: Dehydrogenase - Sphingomonas sp. SKA58
          Length = 272

 Score =  113 bits (271), Expect = 6e-24
 Identities = 76/232 (32%), Positives = 110/232 (47%), Gaps = 5/232 (2%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ L   GA+V++            QS+R+ G    G+   +A  +    L      +
Sbjct: 23  ACARALARAGATVILADIAAERAQAVAQSIRASGGQAHGMALDLAQEDSITALVVDVMRQ 82

Query: 583 FGGVDILXXXXXXX-----XXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG 419
              +DIL                S+LD D   WD+ F VN + + L+ K   P ++  GG
Sbjct: 83  HQRIDILHNNAADTRLEQMAADGSLLDLDAATWDRAFHVNARGTMLMIKAVAPHMIAGGG 142

Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
           GSI+  S+  A        +Y  SK  +  LT+  A +    NIRVN VAPG+V++  A 
Sbjct: 143 GSIINTSTGVALTGDINNPSYSASKAAVNALTRNAAVQFGRFNIRVNAVAPGLVLSPLAR 202

Query: 238 AITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            +   E  A     +V L R   PE+IAGAV FLASD A++ITG+ + V GG
Sbjct: 203 EMMTPEQIA-MIQRHVLLPRESVPEDIAGAVLFLASDGAAFITGQVIGVDGG 253


>UniRef50_A1R613 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=3;
           Actinomycetales|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Arthrobacter aurescens
           (strain TC1)
          Length = 247

 Score =  113 bits (271), Expect = 6e-24
 Identities = 72/228 (31%), Positives = 112/228 (49%), Gaps = 2/228 (0%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           IA+RL   G  +VI  +      +A  +LR  G     V+  +A+      L   A  + 
Sbjct: 18  IAERLAGSGDRIVIAEKNPDLAEQAAAALRGRGFDATAVITDIADKVSVADL-AAAVQQL 76

Query: 580 GGVDILXXXXXXXXXXX--SILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           GG D L             +  + DE  + ++  VN   +WL++K  Y +L +  GGSIV
Sbjct: 77  GGADALVNNAALADGVGGDTFWELDEAFFQRVMTVNAYGTWLVSKHLYHQLAQSPGGSIV 136

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            I+S AA   +  L  Y  SK  +L +T+ +A +     +RVN VAPG+   +   ++  
Sbjct: 137 NIASDAALYGSPRLVHYVGSKGAVLAMTRTMARDAGPAGVRVNAVAPGLTRVEATESVPA 196

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           S     +   N  L R  +P++++GAV FL SD A +ITG+T+VV GG
Sbjct: 197 SRYRLYE--ENRVLPRDQQPKDVSGAVQFLLSDAAGFITGQTIVVDGG 242


>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Leptospira interrogans
          Length = 259

 Score =  112 bits (270), Expect = 8e-24
 Identities = 73/229 (31%), Positives = 106/229 (46%), Gaps = 1/229 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATS 587
           AIA  +  EG  +V+    +  + +A   +  E G+   G+ C+V   E    +      
Sbjct: 28  AIANTIAKEGGDIVLVDLNKEQIEQAAADVAKEFGVKTLGLSCNVTKPEDCDSVIAGVKE 87

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           KFG +D L            I    EQ +D + DVN+K  +L+ K A   L+K   G IV
Sbjct: 88  KFGKLDFLVNNAGVLKDNLFIR-MSEQEFDFVLDVNLKGVFLMTKYASKLLLKAESGRIV 146

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            ISS++          Y  SK  ++ LTK  A E    N+ VN V PG V T   +++  
Sbjct: 147 NISSVSGLTGQPGQANYSSSKAGVIALTKVAAREFAGRNVLVNAVCPGYVQTDMTASLPE 206

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
                    + +PL+R G  +EIA AV F  SD ++YITG  + V GGA
Sbjct: 207 EVQKKLTDPAFIPLRRPGTQQEIANAVKFFLSDQSNYITGTYLRVDGGA 255


>UniRef50_Q39A64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Burkholderia sp. 383|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 257

 Score =  112 bits (270), Expect = 8e-24
 Identities = 74/235 (31%), Positives = 118/235 (50%), Gaps = 4/235 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           +IA R  +EGASVV  + + +        L  +G+ V        + E    L +    +
Sbjct: 26  SIALRFANEGASVVATTSRNTAQLDETCRLAGDGVIVARQA-DAGSAEQVEALIDFVERR 84

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG +D++            ++DT E  WD + DVN+K  +L  K A P +++ GGGSIV 
Sbjct: 85  FGRLDVMCNNAGVIREAR-LVDTTEADWDAVMDVNLKGVFLGCKYAIPAMIRAGGGSIVN 143

Query: 403 ISSIAAYQPTEPL-GAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
           + S +++   EPL  AY  SK  +L LT+ +A E   + IR N V PG + T       +
Sbjct: 144 LGSTSSF-VGEPLHAAYCASKGGVLMLTRCVAIEHAKDRIRANAVCPGWIDTPMNKPFID 202

Query: 226 SEAGAEKS---LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
           +  G +     L  V     G PE++A    FLAS+++S++TG +++V GG  A+
Sbjct: 203 ALGGRDAMDTLLDAVQPLGMGTPEQVADVALFLASNESSFVTGTSILVDGGLTAQ 257


>UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 306

 Score =  112 bits (270), Expect = 8e-24
 Identities = 74/223 (33%), Positives = 112/223 (50%)
 Frame = -3

Query: 739 EGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILX 560
           EGA VV C+      G+   + ++ G     V   V + E   R+   A  +FG +D+L 
Sbjct: 89  EGARVV-CADVS---GREALTAKAVGDGAIAVHVDVTSTEDIERMITTAVDRFGKLDVLY 144

Query: 559 XXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQ 380
                      + +  E  +D +  VNVK  +L  K A P ++  GGGSI+  +S A   
Sbjct: 145 NNAGFTGPIVPLAEAGEDYFDAVMAVNVKGVYLGMKAAIPVMLAGGGGSIINTASAAGLV 204

Query: 379 PTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSL 200
             + L  Y  +K  ++ LT++ A +   + IRVN V PG   T+ A A  +S    E  +
Sbjct: 205 GWKGLAVYAATKGAVVQLTRSAALDYAAKGIRVNAVCPGATWTRQADAEDDS-LPPEGVV 263

Query: 199 SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
              P++R+G P+E+A A  FLASDDAS++TG  + V GG  AR
Sbjct: 264 PPQPMRRWGMPDELAAAALFLASDDASFVTGVALPVDGGYVAR 306


>UniRef50_Q3W9J0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 259

 Score =  112 bits (270), Expect = 8e-24
 Identities = 75/237 (31%), Positives = 114/237 (48%), Gaps = 10/237 (4%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A+  RL  EGA VV+    E+       ++    I   GV   V+  +      +VA + 
Sbjct: 22  AVCDRLAREGAKVVVADLDEAAAKHVADTVGGGAI---GVAADVSTPDGATACVDVAVAA 78

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGS-IV 407
           FG +D+L            + D D   + K+F VNV  ++L A+ A  +L  +GGG  I+
Sbjct: 79  FGRLDLLHANAGVECVVQPVADFDPGDYHKVFGVNVLGAFLSAQAAVRQLTAQGGGGQIL 138

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI-- 233
           F +SIAA   T     Y  SK  + G+ + +A E     IRVN +APG V ++   A+  
Sbjct: 139 FTASIAALMGTGGTSVYNASKHAVHGIARCLALEVAGTGIRVNTLAPGAVESRMMDALGA 198

Query: 232 -TNSEAGAEKS------LSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              + AGA+ +       + +PL R+  PEEIA   A++ SD+  Y+  E V V GG
Sbjct: 199 GLGAMAGADAAGFRTARTAALPLGRYATPEEIAATAAWILSDEVPYLHNEVVTVGGG 255


>UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=4;
           Bradyrhizobiaceae|Rep: Short-chain
           dehydrogenase/reductase - Rhodopseudomonas palustris
           (strain HaA2)
          Length = 259

 Score =  112 bits (270), Expect = 8e-24
 Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 6/231 (2%)
 Frame = -3

Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
           L   GA +V   R  + + +AV +L +    +  +   V   +        A  + G +D
Sbjct: 29  LAERGARIVAIDRDRTALDQAVAALPASAQPL-ALTADVTQEDQVAAYVRAALERCGRID 87

Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIA 389
           +             I+ T    + ++ DVNV   +L  K   P +++ G GSI+  +SIA
Sbjct: 88  VFYNNAGIEGDIAPIVRTSLDAFRRVLDVNVVGVFLGMKHVLPAMLQLGSGSIINTASIA 147

Query: 388 AYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN------ 227
               +  + AY  SK  ++G+TK  A E     +RVNCV PG++ ++  SAI        
Sbjct: 148 GLIGSNDIIAYTASKHAVIGMTKTAALECGDSGVRVNCVCPGLIDSRMLSAIVEGRNPGP 207

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           +    +K +  +P +R G   E+A  VAFLASD+ASY++G    V GG  A
Sbjct: 208 TPVPNDKIVDRIPARRLGHAAEVASVVAFLASDEASYVSGAAYTVDGGRTA 258


>UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=4;
           Bacteria|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Psychroflexus
           torquis ATCC 700755
          Length = 269

 Score =  112 bits (270), Expect = 8e-24
 Identities = 80/231 (34%), Positives = 108/231 (46%), Gaps = 4/231 (1%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A AK   S+GA+VVI  R    V KA Q L      V+G+V  V +      L     S 
Sbjct: 39  ASAKEFKSQGATVVITGRDSEKVAKASQELG-----VKGIVADVKSLSAIDDLVAQVKSD 93

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG VD+L            +    E+++D    +N K ++   ++  P L    G S++ 
Sbjct: 94  FGKVDVLFVNAGIFQPAP-VGQISEEMFDHQMSINFKGAFFTTEKFLPIL--NDGASVIN 150

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
           +SS+ AY        Y  SK  L   T+  A E     IR+N V PG V T         
Sbjct: 151 LSSVNAYTGMPNTAVYAASKAALNAYTRTAATELAPRKIRINSVNPGPVSTPIYGKTGME 210

Query: 223 EAG----AEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
           E      AE   + +PLKRFG+PE+IA  V+FLASDDAS+ITG    + GG
Sbjct: 211 EEQLNGFAEAMQNRIPLKRFGQPEDIAKLVSFLASDDASFITGSEYNIDGG 261


>UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholderia
           xenovorans LB400|Rep: Putative dehydrogenase -
           Burkholderia xenovorans (strain LB400)
          Length = 291

 Score =  112 bits (270), Expect = 8e-24
 Identities = 76/228 (33%), Positives = 108/228 (47%), Gaps = 1/228 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           AI  R    G+ +V+   + S++  A Q L + GI    + C VA+    +         
Sbjct: 33  AIVDRFARSGSRIVLLELRTSSLADAEQRLAAAGIESVSIECDVADESSVKNAAGRTVEH 92

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
           FG  D+L           SI       WD+   +N++  +L  K     ++ +G GSIV 
Sbjct: 93  FGRCDVLINNAATLAPATSIEKLLVADWDRTLAINLRGVFLTTKYLGALMLNQGSGSIVN 152

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-SAITN 227
           I+SIAA  P      YG SK  +L  T+  A E     IR N V+PG + T  + S    
Sbjct: 153 IASIAATAPNAS-PQYGASKAAVLAFTRHTAVEWGPRGIRANAVSPGFIRTPLSESNYAE 211

Query: 226 SEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
            E  A +S + VP +R G P +IA AVAFLA D AS+I G+ + V GG
Sbjct: 212 PEMLARRS-NMVPSRRLGLPGDIAEAVAFLAGDGASFINGQELAVDGG 258


>UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4;
           Gammaproteobacteria|Rep: Oxidoreductase - Alcanivorax
           borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 256

 Score =  112 bits (270), Expect = 8e-24
 Identities = 70/232 (30%), Positives = 108/232 (46%), Gaps = 3/232 (1%)
 Frame = -3

Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
           +A+ LG  GA++V+       +     +L  +G+ V  + C V++    + + + A S+F
Sbjct: 25  LAQELGKRGAALVLGDINMDALNPLADTLAEQGVKVAALRCDVSSEADCKAMVDAALSQF 84

Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
           G +D+                  E+V D+  +VNVK      K    + +K GGGSIV +
Sbjct: 85  GHLDLAVNNAGIAHGFIPFTQLSEEVLDQQMNVNVKGVMFGMKHQI-DAMKVGGGSIVNV 143

Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKF---ASAIT 230
           SS+A       +GAY  +K  ++GLT+  A E    NIRVN + P    T          
Sbjct: 144 SSMAGLGGAPKIGAYSAAKHAVIGLTRTAAVEYAKRNIRVNAICPFYTHTPMLDEGELAK 203

Query: 229 NSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
           N E       S  P+KR G+P EI  A+  L S   SY++G+ + V GG  A
Sbjct: 204 NREQVHAMLASGCPMKRLGQPSEIVAAMLMLLSPANSYMSGQALAVDGGVSA 255


>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 262

 Score =  112 bits (270), Expect = 8e-24
 Identities = 71/230 (30%), Positives = 114/230 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A+ L  EGA VV+    + N GK++ +    G T   V C V++      L + A  +
Sbjct: 23  ATARLLAREGAHVVLADVND-NGGKSIAA--DLGPTAMAVKCDVSSAAEVEALVKAAVER 79

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +DIL           S+ +     W+++  +++ S +     A P + +  G +IV 
Sbjct: 80  HGRIDILFNNAGIGSFGTSV-EIQPAEWERVIAIDLHSVYYACHFAIPHMPR--GSAIVN 136

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +SI+         AY  +K  ++  T+A+A +   + IRVN + PG+V T   + +   
Sbjct: 137 TASISGLGGDYRFAAYNAAKGAVVNYTRALAVDHGRDGIRVNALCPGLVETPITAGVQQM 196

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPA 74
               E  L  +P++R  +PEE+A  VAFLASDDASY+TG  +V  GG  A
Sbjct: 197 PGLREDWLKRIPMERAAQPEEMASVVAFLASDDASYVTGTIMVADGGRTA 246


>UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Sphingomonas wittichii RW1|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
          Length = 250

 Score =  112 bits (270), Expect = 8e-24
 Identities = 78/228 (34%), Positives = 108/228 (47%), Gaps = 4/228 (1%)
 Frame = -3

Query: 754 KRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGG 575
           +R  + GA VV   R+    G+  Q  R  G+ V   V  V +      L +   S +G 
Sbjct: 24  ERFAAGGARVVAVDRRRDAGGRIAQGFRERGLDVRCRVADVTSAVQVATLGQHVRSAYGR 83

Query: 574 VDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISS 395
            DIL            I+  D   WD++  VN KS++L+ +   P +   G G+I+ ISS
Sbjct: 84  ADILVNNAGMLSFAP-IVGADANEWDRVQKVNCKSAFLMIRTFAPLMA--GKGAIINISS 140

Query: 394 IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAG 215
            A  +PT    AY ++K  LL LT+  A E +   IRVN +APG + T    +       
Sbjct: 141 SAGLKPTANTAAYSIAKAGLLMLTQIAAME-LGPGIRVNAIAPGPLDTDMPHSYLKGHPH 199

Query: 214 A----EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
                E  +    +KR G+P EIA  VAFLASD ASYI G T+   GG
Sbjct: 200 KGQIMEHMIERTIVKRLGQPGEIAEVVAFLASDAASYINGATITADGG 247


>UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Rhizobiales|Rep: Short-chain
           dehydrogenase/reductase SDR - Methylobacterium sp. 4-46
          Length = 252

 Score =  112 bits (270), Expect = 8e-24
 Identities = 67/227 (29%), Positives = 112/227 (49%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
           A A RL  EGA  V+  R+   +      + +EG +   V C + N      +   AT  
Sbjct: 22  AAAIRLAREGARSVLVGRRLEPLEAVAAEIAAEGGSALPVACDIGNPAEVEAMVRQATRA 81

Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
            G +D L            + +TD   ++++   N+  ++L  K + P L    GG++V 
Sbjct: 82  NGRIDGLFANAGVLGAFKPLAETDATDFEELVGTNLLGTFLSIKHSLPHL---RGGAVVI 138

Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
            +S          GAY  +K  L+ +   +A E    ++RVN ++PGI++T  A A+ + 
Sbjct: 139 NASWTVNSVMPGAGAYAATKGALIAMMHTLALEQGPRDVRVNSISPGIILTPMADAVLDP 198

Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
              A K  ++ PL R G P+++AG VA+L SDDA ++TG+ ++V GG
Sbjct: 199 AFSA-KLAAHAPLGRNGTPDDVAGTVAWLLSDDARFVTGQDILVDGG 244


>UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Saccharopolyspora
           erythraea NRRL 2338|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 253

 Score =  112 bits (270), Expect = 8e-24
 Identities = 76/233 (32%), Positives = 119/233 (51%), Gaps = 2/233 (0%)
 Frame = -3

Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATS 587
           A A  L   GA +V+  R+E     AV+ L ++    V  +V  VA+ +  R    +AT 
Sbjct: 27  ATAALLRERGARLVVTDRRE-----AVEELAADDPDDVAALVGDVADEDIARAATRLATQ 81

Query: 586 KFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIV 407
           +FG +DIL            + DT    +D+I  VN + +++ A+EA+  +   GGG+IV
Sbjct: 82  RFGRLDILVNNAGRTLNKP-VTDTTVDDFDEIMRVNARGNFVQAREAFRAMEAGGGGAIV 140

Query: 406 FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITN 227
            I+S+++        AY  SK  L  +T+ +A E   + IR N V PG+V T     + +
Sbjct: 141 SIASVSSVVAFRTQTAYAASKGALAQITRVLAIEGGPKGIRSNAVLPGVVDTDIMEGVVD 200

Query: 226 SEAGAEKSLSNV-PLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPAR 71
                  S  +  P+ R G+PEE+A AVAFL  D ++++TG  V V GG  A+
Sbjct: 201 DGREMLASFGSAHPIGRIGKPEEVAEAVAFLVCDASAFVTGALVAVDGGWTAQ 253


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 817,644,637
Number of Sequences: 1657284
Number of extensions: 17187409
Number of successful extensions: 63390
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 57486
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 60540
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63792713725
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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