Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV10a03r
(765 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 239 1e-62
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 239 1e-62
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 239 1e-62
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 239 1e-62
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 239 1e-62
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 238 1e-62
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 235 2e-61
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 201 3e-51
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 201 3e-51
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 201 3e-51
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 198 2e-50
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 155 5e-50
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 165 2e-40
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 162 1e-39
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 105 1e-22
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 105 1e-22
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 105 1e-22
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 105 1e-22
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 105 2e-22
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 105 2e-22
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 105 2e-22
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 105 2e-22
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 105 2e-22
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 105 2e-22
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 105 2e-22
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 105 2e-22
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 104 3e-22
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 100 7e-21
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 97 8e-20
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 97 8e-20
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 97 8e-20
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 96 1e-19
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 93 1e-18
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 93 1e-18
DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retin... 63 3e-18
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 91 4e-18
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 90 7e-18
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 90 7e-18
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 90 7e-18
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 90 9e-18
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 89 2e-17
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 84 5e-16
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 84 5e-16
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 84 6e-16
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 84 6e-16
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 83 1e-15
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 83 1e-15
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 83 1e-15
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 83 1e-15
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 83 1e-15
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 83 1e-15
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 83 1e-15
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 83 1e-15
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 77 9e-14
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 69 2e-11
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 69 2e-11
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 69 2e-11
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 64 7e-10
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 64 7e-10
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 64 7e-10
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 64 7e-10
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 64 7e-10
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 64 7e-10
AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retin... 63 1e-09
AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retin... 63 1e-09
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 62 3e-09
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 62 3e-09
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 60 6e-09
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 55 2e-07
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 55 2e-07
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 55 2e-07
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 55 2e-07
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 54 6e-07
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 54 6e-07
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 53 1e-06
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 53 1e-06
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 53 1e-06
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 53 1e-06
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 53 1e-06
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 53 1e-06
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 53 1e-06
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 53 1e-06
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 53 1e-06
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 53 1e-06
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 52 2e-06
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 52 2e-06
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 52 2e-06
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 52 2e-06
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 50 1e-05
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 48 4e-05
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 48 5e-05
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 48 5e-05
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 48 5e-05
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 48 5e-05
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 48 5e-05
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 48 5e-05
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 48 5e-05
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 48 5e-05
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 48 5e-05
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 48 5e-05
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 48 5e-05
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 46 1e-04
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 46 2e-04
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 46 2e-04
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 46 2e-04
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 42 0.002
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 42 0.002
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 42 0.002
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 42 0.002
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 42 0.002
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 42 0.002
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 41 0.006
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 41 0.006
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 41 0.006
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 40 0.007
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 40 0.007
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 40 0.007
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 37 0.069
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 37 0.069
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 37 0.091
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 37 0.091
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.091
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.091
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.091
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.091
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 36 0.16
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 35 0.28
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.28
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.28
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 35 0.28
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 35 0.28
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.28
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.28
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 33 0.85
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 33 0.85
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 33 0.85
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 33 1.5
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 33 1.5
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 33 1.5
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 33 1.5
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 33 1.5
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 33 1.5
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 33 1.5
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 33 1.5
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 33 1.5
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 32 2.0
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 32 2.0
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 32 2.0
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 32 2.0
Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein. 32 2.6
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 31 4.5
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 31 6.0
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 31 6.0
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 31 6.0
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 31 6.0
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 31 6.0
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 31 6.0
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 31 6.0
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 239 bits (584), Expect = 1e-62
Identities = 116/232 (50%), Positives = 150/232 (64%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL A
Sbjct: 47 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKL 106
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 107 HGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 166
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAA+ P+ Y VSKT LLGLTK +A E NIRVNC+APG++ T F+ +
Sbjct: 167 VSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMD 226
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
+ E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 227 KEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 239 bits (584), Expect = 1e-62
Identities = 116/232 (50%), Positives = 150/232 (64%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL A
Sbjct: 47 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKL 106
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 107 HGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 166
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAA+ P+ Y VSKT LLGLTK +A E NIRVNC+APG++ T F+ +
Sbjct: 167 VSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMD 226
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
+ E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 227 KEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 239 bits (584), Expect = 1e-62
Identities = 116/232 (50%), Positives = 150/232 (64%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL A
Sbjct: 47 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKL 106
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 107 HGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 166
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAA+ P+ Y VSKT LLGLTK +A E NIRVNC+APG++ T F+ +
Sbjct: 167 VSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMD 226
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
+ E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 227 KEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 239 bits (584), Expect = 1e-62
Identities = 116/232 (50%), Positives = 150/232 (64%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL A
Sbjct: 47 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKL 106
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 107 HGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 166
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAA+ P+ Y VSKT LLGLTK +A E NIRVNC+APG++ T F+ +
Sbjct: 167 VSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMD 226
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
+ E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 227 KEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 239 bits (584), Expect = 1e-62
Identities = 116/232 (50%), Positives = 150/232 (64%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL A
Sbjct: 29 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKL 88
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 89 HGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 148
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAA+ P+ Y VSKT LLGLTK +A E NIRVNC+APG++ T F+ +
Sbjct: 149 VSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMD 208
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
+ E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 209 KEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 260
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 238 bits (583), Expect = 1e-62
Identities = 115/232 (49%), Positives = 151/232 (65%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL +A
Sbjct: 29 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKL 88
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL S++D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 89 HGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 148
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAA+ P+ Y VSKT LLGLTK +A E NIRVNC+APG++ T F+ +
Sbjct: 149 VSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMD 208
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
+ E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 209 KEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 260
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 235 bits (574), Expect = 2e-61
Identities = 115/232 (49%), Positives = 149/232 (64%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VC V E R RL A
Sbjct: 47 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMVGKAEDRERLVATAVKL 106
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL SI+D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 107 HGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 166
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAA+ P+ Y VSKT LLGLTK +A E NIRVNC+APG++ T F+ +
Sbjct: 167 VSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMD 226
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
+ E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 227 KEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 278
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 201 bits (490), Expect = 3e-51
Identities = 105/226 (46%), Positives = 137/226 (60%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VVI SRK+ NV +A+ L+ EG++V G+VCHV E R +L A
Sbjct: 51 AIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEH 110
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GGVD L S L T EQ+WDKI VNVKS LL + P + R G +++
Sbjct: 111 CGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG-AVIL 169
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAAY P LG Y VSKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +
Sbjct: 170 VSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGN 229
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
E+ + + L+R G E+ AG V+FL S DASY+ GE + VAG
Sbjct: 230 ESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 275
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 201 bits (490), Expect = 3e-51
Identities = 105/226 (46%), Positives = 137/226 (60%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VVI SRK+ NV +A+ L+ EG++V G+VCHV E R +L A
Sbjct: 42 AIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEH 101
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GGVD L S L T EQ+WDKI VNVKS LL + P + R G +++
Sbjct: 102 CGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG-AVIL 160
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAAY P LG Y VSKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +
Sbjct: 161 VSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGN 220
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
E+ + + L+R G E+ AG V+FL S DASY+ GE + VAG
Sbjct: 221 ESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 266
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 201 bits (490), Expect = 3e-51
Identities = 105/226 (46%), Positives = 137/226 (60%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VVI SRK+ NV +A+ L+ EG++V G+VCHV E R +L A
Sbjct: 51 AIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEH 110
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GGVD L S L T EQ+WDKI VNVKS LL + P + R G +++
Sbjct: 111 CGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG-AVIL 169
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SSIAAY P LG Y VSKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +
Sbjct: 170 VSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGN 229
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
E+ + + L+R G E+ AG V+FL S DASY+ GE + VAG
Sbjct: 230 ESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 275
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 198 bits (482), Expect = 2e-50
Identities = 103/226 (45%), Positives = 136/226 (60%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VVI SRK+ NV +A+ L+ EG++V G+VCHV E R +L A
Sbjct: 51 AIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEH 110
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GGVD L S L T EQ+WDKI VNVKS L + P + R G +++
Sbjct: 111 CGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLLSQLLPYMENRRG-AVIL 169
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+SS+AAY P LG Y VSKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +
Sbjct: 170 VSSVAAYNPVVALGVYSVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGN 229
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
E+ + + L+R G E+ AG V+FL S DASY+ GE + VAG
Sbjct: 230 ESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 275
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 155 bits (375), Expect(2) = 5e-50
Identities = 73/140 (52%), Positives = 95/140 (67%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y VSKT LLGLTK +A
Sbjct: 105 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 164
Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASD 128
E NIRVNC+APG++ T F+ + + E + ++R G PE+ AG V+FL S+
Sbjct: 165 ELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 224
Query: 127 DASYITGETVVVAGGAPARL 68
DASYITGETVVV GG P+RL
Sbjct: 225 DASYITGETVVVGGGTPSRL 244
Score = 63.7 bits (148), Expect(2) = 5e-50
Identities = 32/59 (54%), Positives = 42/59 (71%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL VAT+
Sbjct: 47 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERL--VATT 103
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 165 bits (401), Expect = 2e-40
Identities = 85/177 (48%), Positives = 109/177 (61%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VVI SRK+ NV +A+ L+ EG++V G+VCHV E R +L A
Sbjct: 51 AIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEH 110
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GGVD L S L T EQ+WDKI VNVKS LL + P + R G+++
Sbjct: 111 CGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENR-RGAVIL 169
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAI 233
+SSIAAY P LG Y VSKT LLGLT+ +A E ++IRVNCV PGI+ T F+ +
Sbjct: 170 VSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVV 226
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 162 bits (394), Expect = 1e-39
Identities = 79/164 (48%), Positives = 103/164 (62%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL + A VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL +A
Sbjct: 45 AIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKL 104
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
GG+DIL S++D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V
Sbjct: 105 HGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVI 164
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 272
+SSIAA+ P+ Y VSKT LLGL +A E NIRVNC+
Sbjct: 165 VSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCL 208
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 105 bits (253), Expect = 1e-22
Identities = 73/235 (31%), Positives = 114/235 (48%), Gaps = 8/235 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS-----EGITVEGVVCHVANHEHRRRLFE 599
AI K L G++VVI SRK + A L++ + V + C++ N E L +
Sbjct: 33 AIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVK 92
Query: 598 VATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG 419
FG ++ L + + W + + N+ ++ + K Y +K G
Sbjct: 93 STLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG 151
Query: 418 GSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
GSIV I I + PL + G ++ + LTK++A E IR+NCVAPG++ ++ A
Sbjct: 152 GSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTA 209
Query: 241 SAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
S ++ E S +P KR G PEE++ V FL S AS+ITG++V V GG
Sbjct: 210 VENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 105 bits (253), Expect = 1e-22
Identities = 73/235 (31%), Positives = 114/235 (48%), Gaps = 8/235 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS-----EGITVEGVVCHVANHEHRRRLFE 599
AI K L G++VVI SRK + A L++ + V + C++ N E L +
Sbjct: 33 AIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVK 92
Query: 598 VATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG 419
FG ++ L + + W + + N+ ++ + K Y +K G
Sbjct: 93 STLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG 151
Query: 418 GSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
GSIV I I + PL + G ++ + LTK++A E IR+NCVAPG++ ++ A
Sbjct: 152 GSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTA 209
Query: 241 SAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
S ++ E S +P KR G PEE++ V FL S AS+ITG++V V GG
Sbjct: 210 VENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 105 bits (253), Expect = 1e-22
Identities = 73/235 (31%), Positives = 114/235 (48%), Gaps = 8/235 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS-----EGITVEGVVCHVANHEHRRRLFE 599
AI K L G++VVI SRK + A L++ + V + C++ N E L +
Sbjct: 52 AIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVK 111
Query: 598 VATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG 419
FG ++ L + + W + + N+ ++ + K Y +K G
Sbjct: 112 STLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG 170
Query: 418 GSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
GSIV I I + PL + G ++ + LTK++A E IR+NCVAPG++ ++ A
Sbjct: 171 GSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTA 228
Query: 241 SAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
S ++ E S +P KR G PEE++ V FL S AS+ITG++V V GG
Sbjct: 229 VENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 283
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 105 bits (253), Expect = 1e-22
Identities = 73/235 (31%), Positives = 114/235 (48%), Gaps = 8/235 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS-----EGITVEGVVCHVANHEHRRRLFE 599
AI K L G++VVI SRK + A L++ + V + C++ N E L +
Sbjct: 33 AIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVK 92
Query: 598 VATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG 419
FG ++ L + + W + + N+ ++ + K Y +K G
Sbjct: 93 STLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG 151
Query: 418 GSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
GSIV I I + PL + G ++ + LTK++A E IR+NCVAPG++ ++ A
Sbjct: 152 GSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTA 209
Query: 241 SAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
S ++ E S +P KR G PEE++ V FL S AS+ITG++V V GG
Sbjct: 210 VENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 105 bits (252), Expect = 2e-22
Identities = 74/235 (31%), Positives = 113/235 (48%), Gaps = 8/235 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRS-----EGITVEGVVCHVANHEHRRRLFE 599
AI K L G++VVI SRK + A L++ + V + C++ N E L +
Sbjct: 33 AIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVK 92
Query: 598 VATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGG 419
FG ++ L + + W + N+ S+ + K Y +K G
Sbjct: 93 STLDTFGKINFLVNNGGGQFLSPAE-HISSKGWHAVLRTNLTGSFYMCKAVYSSWMKEHG 151
Query: 418 GSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
GSIV I I + PL + G ++ + LTK++A E IR+NCVAPG++ ++ A
Sbjct: 152 GSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTA 209
Query: 241 SAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
S ++ E S +P KR G PEE++ V FL S AS+ITG++V V GG
Sbjct: 210 VENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 105 bits (251), Expect = 2e-22
Identities = 74/236 (31%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 84
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L E WDK+ VN+K ++L+ + A LV
Sbjct: 85 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS 144
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E IR N V PG + T
Sbjct: 145 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 205 PMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 105 bits (251), Expect = 2e-22
Identities = 74/236 (31%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 84
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L E WDK+ VN+K ++L+ + A LV
Sbjct: 85 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS 144
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E IR N V PG + T
Sbjct: 145 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 205 PMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 105 bits (251), Expect = 2e-22
Identities = 74/236 (31%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 84
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L E WDK+ VN+K ++L+ + A LV
Sbjct: 85 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS 144
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E IR N V PG + T
Sbjct: 145 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 205 PMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 105 bits (251), Expect = 2e-22
Identities = 74/236 (31%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 84
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L E WDK+ VN+K ++L+ + A LV
Sbjct: 85 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS 144
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E IR N V PG + T
Sbjct: 145 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 205 PMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 105 bits (251), Expect = 2e-22
Identities = 74/236 (31%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 84
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L E WDK+ VN+K ++L+ + A LV
Sbjct: 85 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS 144
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E IR N V PG + T
Sbjct: 145 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 205 PMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 105 bits (251), Expect = 2e-22
Identities = 74/236 (31%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 84
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L E WDK+ VN+K ++L+ + A LV
Sbjct: 85 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS 144
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E IR N V PG + T
Sbjct: 145 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 205 PMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 105 bits (251), Expect = 2e-22
Identities = 74/236 (31%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 84
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L E WDK+ VN+K ++L+ + A LV
Sbjct: 85 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS 144
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E IR N V PG + T
Sbjct: 145 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 205 PMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 104 bits (250), Expect = 3e-22
Identities = 59/136 (43%), Positives = 79/136 (58%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVS 347
++D E+VWDK D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y VS
Sbjct: 2 LMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVS 61
Query: 346 KTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPLKRFGRP 167
KT LLGL +A E NIRVNC+ + +++ ASA G P
Sbjct: 62 KTALLGLNNTLAIELAPRNIRVNCL--HLDLSRLASA-----------------GWLGEP 102
Query: 166 EEIAGAVAFLASDDAS 119
E+ AG V+FL S+DAS
Sbjct: 103 EDCAGIVSFLCSEDAS 118
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 100 bits (239), Expect = 7e-21
Identities = 72/236 (30%), Positives = 103/236 (43%), Gaps = 9/236 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG--------VVCHVANHEHRRR 608
A++ RL EGA+V C + + V+ L G + EG V+ R
Sbjct: 24 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARC 82
Query: 607 LFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK 428
L E + F + +L WDK+ VN+K ++L+ + A LV
Sbjct: 83 LLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDKVIAVNLKGTFLVTQAAAQALVS 142
Query: 427 RG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT 251
G GSI+ ISSI Y SK ++GLT+ A E I N V PG + T
Sbjct: 143 NGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIPCNSVLPGFIAT 202
Query: 250 KFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ +K +P+ G PE++A VAFLAS+D+ YITG +V V GG
Sbjct: 203 PMTKKVPKKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 256
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 96.7 bits (230), Expect = 8e-20
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 350
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 349 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 182
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 181 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESTYVTGNPVIIDGG 242
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 96.7 bits (230), Expect = 8e-20
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 350
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 349 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 182
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 181 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 96.7 bits (230), Expect = 8e-20
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 350
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 349 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 182
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 181 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 96.3 bits (229), Expect = 1e-19
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 5/153 (3%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA-YQPTEPLGAYGV 350
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+ + Y
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYST 149
Query: 349 SKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAITNSEAGAEKSLSNVPLK 182
+K ++GLTK++A + + + IR NCV PG V T + A N E L
Sbjct: 150 TKAAVIGLTKSLAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209
Query: 181 RFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
RF EEIA +LASD+++Y+TG V++ GG
Sbjct: 210 RFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 93.1 bits (221), Expect = 1e-18
Identities = 66/227 (29%), Positives = 99/227 (43%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A+A+ + +G + + +R A L + + C VA + FE
Sbjct: 17 AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS---CDVAKEHDVQNTFEELEKH 73
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
G V+ L + E + ++ N+ S L K A ++++ GGSIV
Sbjct: 74 LGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSMLTCKAAMRTMIQQQGGSIVN 132
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+ SI + Y SK L+G ++A+A E + IRVN VAPG V T +
Sbjct: 133 VGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKE- 191
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
E N+PL RFG E+A AV FL ++ YITG +VV GG
Sbjct: 192 ----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 93.1 bits (221), Expect = 1e-18
Identities = 66/227 (29%), Positives = 99/227 (43%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A+A+ + +G + + +R A L + + C VA + FE
Sbjct: 17 AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS---CDVAKEHDVQNTFEEMEKH 73
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
G V+ L + E + ++ N+ S L K A ++++ GGSIV
Sbjct: 74 LGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSMLTCKAAMRTMIQQQGGSIVN 132
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNS 224
+ SI + Y SK L+G ++A+A E + IRVN VAPG V T +
Sbjct: 133 VGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKE- 191
Query: 223 EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
E N+PL RFG E+A AV FL ++ YITG +VV GG
Sbjct: 192 ----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232
>DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B2 isoform protein.
Length = 160
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -3
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 113 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 160
Score = 61.7 bits (143), Expect(2) = 3e-18
Identities = 32/59 (54%), Positives = 41/59 (69%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATS 587
AIA RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL VAT+
Sbjct: 8 AIAWRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERL--VATT 64
Score = 50.4 bits (115), Expect(2) = 3e-18
Identities = 21/38 (55%), Positives = 29/38 (76%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPT 374
D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+
Sbjct: 66 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPS 103
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 91.1 bits (216), Expect = 4e-18
Identities = 62/231 (26%), Positives = 113/231 (48%), Gaps = 4/231 (1%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
I + + GA VVIC + ES G+A++ + + +C V + + L +F
Sbjct: 25 IVRAFVNSGARVVICDKDESG-GRALEQELPGAVFI---LCDVTQEDDVKTLVSETIRRF 80
Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
G +D + +T Q + ++ ++N+ ++ L K A P L ++ G+++ I
Sbjct: 81 GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL-RKSQGNVINI 139
Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAI 233
SS+ Y +K + +TKA+A + +RVNC++PG + T + A+ +
Sbjct: 140 SSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALM 199
Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
+ A + + PL R G+P E+ A FLAS +A++ TG ++V GGA
Sbjct: 200 PDPRASIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGA 249
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 90.2 bits (214), Expect = 7e-18
Identities = 62/231 (26%), Positives = 113/231 (48%), Gaps = 4/231 (1%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
I + + GA VVIC + ES G+A++ + + +C V + + L +F
Sbjct: 25 IVRAFVNSGARVVICDKDESG-GRALEQELPGAVFI---LCDVTQEDDVKTLVSETIRRF 80
Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
G +D + +T Q + ++ ++N+ ++ L K A P L ++ G+++ I
Sbjct: 81 GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL-RKSQGNVINI 139
Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAI 233
SS+ Y +K + +TKA+A + +RVNC++PG + T + A+ +
Sbjct: 140 SSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALM 199
Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
+ A + + PL R G+P E+ A FLAS +A++ TG ++V GGA
Sbjct: 200 PDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGA 249
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 90.2 bits (214), Expect = 7e-18
Identities = 62/231 (26%), Positives = 113/231 (48%), Gaps = 4/231 (1%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
I + + GA VVIC + ES G+A++ + + +C V + + L +F
Sbjct: 25 IVRAFVNSGARVVICDKDESG-GRALEQELPGAVFI---LCDVTQEDDVKTLVSETIRRF 80
Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
G +D + +T Q + ++ ++N+ ++ L K A P L ++ G+++ I
Sbjct: 81 GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL-RKSQGNVINI 139
Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAI 233
SS+ Y +K + +TKA+A + +RVNC++PG + T + A+ +
Sbjct: 140 SSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALM 199
Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
+ A + + PL R G+P E+ A FLAS +A++ TG ++V GGA
Sbjct: 200 PDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGA 249
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 90.2 bits (214), Expect = 7e-18
Identities = 62/231 (26%), Positives = 113/231 (48%), Gaps = 4/231 (1%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKF 581
I + + GA VVIC + ES G+A++ + + +C V + + L +F
Sbjct: 25 IVRAFVNSGARVVICDKDESG-GRALEQELPGAVFI---LCDVTQEDDVKTLVSETIRRF 80
Query: 580 GGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFI 401
G +D + +T Q + ++ ++N+ ++ L K A P L ++ G+++ I
Sbjct: 81 GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL-RKSQGNVINI 139
Query: 400 SSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVT----KFASAI 233
SS+ Y +K + +TKA+A + +RVNC++PG + T + A+ +
Sbjct: 140 SSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALM 199
Query: 232 TNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGA 80
+ A + + PL R G+P E+ A FLAS +A++ TG ++V GGA
Sbjct: 200 PDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGA 249
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 89.8 bits (213), Expect = 9e-18
Identities = 43/92 (46%), Positives = 57/92 (61%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL A
Sbjct: 29 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKL 88
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIF 488
GG+DIL SI+D E+VWDK++
Sbjct: 89 HGGIDILVSNAAVNPFFGSIMDVTEEVWDKLW 120
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -3
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 127 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 174
>AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retinol
dehydrogenase A2 isoform protein.
Length = 188
Score = 88.6 bits (210), Expect = 2e-17
Identities = 43/90 (47%), Positives = 55/90 (61%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV E R RL A
Sbjct: 47 AIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKL 106
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDK 494
GG+DIL SI+D E+VWDK
Sbjct: 107 HGGIDILVSNAAVNPFFGSIMDVTEEVWDK 136
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 84.2 bits (199), Expect = 5e-16
Identities = 67/223 (30%), Positives = 106/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ A L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIAARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 84.2 bits (199), Expect = 5e-16
Identities = 42/91 (46%), Positives = 54/91 (59%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
AIA+RL +GA VVI SRK+ NV +A+ L+ EG++V G+VCHV E R +L A
Sbjct: 68 AIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEH 127
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKI 491
GGVD L S L T EQ+WDK+
Sbjct: 128 CGGVDFLVCSAGVNPLVGSTLGTSEQIWDKV 158
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 83.8 bits (198), Expect = 6e-16
Identities = 60/228 (26%), Positives = 107/228 (46%), Gaps = 8/228 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGI--TVEGVVCHVANHEHRRRLFEVAT 590
A+A+ L +G VV C+R N+ + +S G T+ C ++N E +F
Sbjct: 26 AVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIR 85
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG--GG 416
S+ GVDI +L W +F+VNV + + +EAY + +R G
Sbjct: 86 SQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDG 144
Query: 415 SIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--VHENIRVNCVAPGIVVTK 248
I+ I+S++ ++ P Y +K + LT+ + E +IR C++PG+V T+
Sbjct: 145 HIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 204
Query: 247 FASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGE 104
FA + + + EK+ + + +PE++A AV ++ S A G+
Sbjct: 205 FAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGD 250
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 83.8 bits (198), Expect = 6e-16
Identities = 60/228 (26%), Positives = 107/228 (46%), Gaps = 8/228 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGI--TVEGVVCHVANHEHRRRLFEVAT 590
A+A+ L +G VV C+R N+ + +S G T+ C ++N E +F
Sbjct: 26 AVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIR 85
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG--GG 416
S+ GVDI +L W +F+VNV + + +EAY + +R G
Sbjct: 86 SQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDG 144
Query: 415 SIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--VHENIRVNCVAPGIVVTK 248
I+ I+S++ ++ P Y +K + LT+ + E +IR C++PG+V T+
Sbjct: 145 HIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 204
Query: 247 FASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGE 104
FA + + + EK+ + + +PE++A AV ++ S A G+
Sbjct: 205 FAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGD 250
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 26 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 77
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 78 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 136
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 137 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 196
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 197 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 239
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 82.6 bits (195), Expect = 1e-15
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVD 569
L + GA VV SR ++++ SL E +E V + + E R A G VD
Sbjct: 27 LHATGARVVAVSRTQADL----DSLVRECPGIEPVCVDLGDWEATER----ALGSVGPVD 78
Query: 568 ILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSI 392
+L L+ ++ +D+ F+VN+++ +++ L+ RG G+IV +SS
Sbjct: 79 LLVNNAAVALLQP-FLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQ 137
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGA 212
+ + Y +K L LTK +A E IRVN V P +V+T A + A
Sbjct: 138 CSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
+ L+ +PL +F E + A+ FL SD + TG T+ V GG
Sbjct: 198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 76.6 bits (180), Expect = 9e-14
Identities = 47/120 (39%), Positives = 68/120 (56%), Gaps = 3/120 (2%)
Frame = -3
Query: 433 VKRGGGSIVFISSIAAYQPTEPLGAY-GVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+K GGSIV I I + PL + G ++ + LTK++A E IR+NCVAPG++
Sbjct: 1 MKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVI 58
Query: 256 VTKFASAITNS--EAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
++ A S ++ E S +P KR G PEE++ V FL AS+ITG++V V GG
Sbjct: 59 YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLPPAASFITGQSVDVDGG 118
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 85 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 144
Query: 313 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 137
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 145 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 204
Query: 136 ASDDASYITGETVVVAGGA 80
AS ASY+TG +V GGA
Sbjct: 205 ASPLASYVTGAVLVADGGA 223
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 313 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 137
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 136 ASDDASYITGETVVVAGGA 80
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 313 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 137
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 136 ASDDASYITGETVVVAGGA 80
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 121 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 180
Query: 313 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 137
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 181 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 240
Query: 136 ASDDASYITGETVVVAGGA 80
AS ASY+TG +V GGA
Sbjct: 241 ASPLASYVTGAVLVADGGA 259
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 313 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 137
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 136 ASDDASYITGETVVVAGGA 80
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 68.5 bits (160), Expect = 2e-11
Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ D++ ++ +++ Y + + GG IV I++ + G +K + +T+ +
Sbjct: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192
Query: 313 ANETVHENIRVNCVAPG-IVVTKFASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFL 137
A E +NIRVN +APG I T+ + +A ++ PL+R G EIA +V +L
Sbjct: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252
Query: 136 ASDDASYITGETVVVAGGA 80
AS ASY+TG +V GGA
Sbjct: 253 ASPLASYVTGAVLVADGGA 271
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
L S GA VI SRK + + + S+ G V + C V + + + G
Sbjct: 79 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHP 138
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISS 395
+I+ + W I D+ + + + E +L+K + G + + I++
Sbjct: 139 NIVINNAAGNFISPTER-LSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITT 197
Query: 394 IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAG 215
I A + + +K + ++K++A E +R N + PG + TK A + +
Sbjct: 198 IYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGT 257
Query: 214 AEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
EK + +P R G EE+A AFL SD AS+I G + GG
Sbjct: 258 FEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGG 302
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
L S GA VI SRK + + + S+ G V + C V + + + G
Sbjct: 79 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHP 138
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISS 395
+I+ + W I D+ + + + E +L+K + G + + I++
Sbjct: 139 NIVINNAAGNFISPTER-LSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITT 197
Query: 394 IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAG 215
I A + + +K + ++K++A E +R N + PG + TK A + +
Sbjct: 198 IYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGT 257
Query: 214 AEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
EK + +P R G EE+A AFL SD AS+I G + GG
Sbjct: 258 FEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGG 302
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
L S GA VI SRK + + + S+ G V + C V + + + G
Sbjct: 79 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHP 138
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISS 395
+I+ + W I D+ + + + E +L+K + G + + I++
Sbjct: 139 NIVINNAAGNFISPTER-LSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITT 197
Query: 394 IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAG 215
I A + + +K + ++K++A E +R N + PG + TK A + +
Sbjct: 198 IYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGT 257
Query: 214 AEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
EK + +P R G EE+A AFL SD AS+I G + GG
Sbjct: 258 FEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGG 302
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
L S GA VI SRK + + + S+ G V + C V + + + G
Sbjct: 79 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHP 138
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISS 395
+I+ + W I D+ + + + E +L+K + G + + I++
Sbjct: 139 NIVINNAAGNFISPTER-LSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITT 197
Query: 394 IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAG 215
I A + + +K + ++K++A E +R N + PG + TK A + +
Sbjct: 198 IYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGT 257
Query: 214 AEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
EK + +P R G EE+A AFL SD AS+I G + GG
Sbjct: 258 FEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGG 302
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/167 (25%), Positives = 70/167 (41%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A+A+ + +G + + +R A L + + C VA + FE
Sbjct: 17 AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS---CDVAKEHDVQNTFEEMEKH 73
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVF 404
G V+ L + E + ++ N+ S L K A ++++ GGSIV
Sbjct: 74 LGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSMLTCKAAMRTMIQQQGGSIVN 132
Query: 403 ISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPG 263
+ SI + Y SK L+G ++A+A E + IRVN VAPG
Sbjct: 133 VGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
L S GA VI SRK + + + S+ G V + C V + + + G
Sbjct: 79 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHP 138
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISS 395
+I+ + W I D+ + + + E +L+K + G + + I++
Sbjct: 139 NIVINNAAGNFISPTER-LSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITT 197
Query: 394 IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAG 215
I A + + +K + ++K++A E +R N + PG + TK A + +
Sbjct: 198 IYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGT 257
Query: 214 AEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
EK + +P R G EE+A AFL SD AS+I G + GG
Sbjct: 258 FEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGG 302
>AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase A1 like protein 1 protein.
Length = 57
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -3
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 10 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 57
>AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform-like protein 1
protein.
Length = 91
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/48 (58%), Positives = 35/48 (72%)
Frame = -3
Query: 211 EKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGGAPARL 68
E + ++R G PE+ AG V+FL S+DASYITGETVVV GG P+RL
Sbjct: 44 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL 91
Score = 31.1 bits (67), Expect = 4.5
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -3
Query: 598 VATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIF 488
+A GG+DIL S++D E+VWDK++
Sbjct: 1 MAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKLW 37
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 6/168 (3%)
Frame = -3
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG--GG 416
S+ GVDI +L W +F+VNV + + +EAY + +R G
Sbjct: 7 SQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDG 65
Query: 415 SIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--VHENIRVNCVAPGIVVTK 248
I+ I+S++ ++ P Y +K + LT+ + E +IR C++PG+V T+
Sbjct: 66 HIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 125
Query: 247 FASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGE 104
FA + + + EK+ + + +PE++A AV ++ S A G+
Sbjct: 126 FAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGD 171
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 6/168 (3%)
Frame = -3
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG--GG 416
S+ GVDI +L W +F+VNV + + +EAY + +R G
Sbjct: 7 SQHSGVDICINNAGLARPDT-LLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDG 65
Query: 415 SIVFISSIAAYQ--PTEPLGAYGVSKTTLLGLTKAIANET--VHENIRVNCVAPGIVVTK 248
I+ I+S++ ++ P Y +K + LT+ + E +IR C++PG+V T+
Sbjct: 66 HIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 125
Query: 247 FASAITNSEAGAEKSLSNVPLKRFGRPEEIAGAVAFLASDDASYITGE 104
FA + + + EK+ + + +PE++A AV ++ S A G+
Sbjct: 126 FAFKLHDKD--PEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGD 171
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/225 (24%), Positives = 95/225 (42%), Gaps = 3/225 (1%)
Frame = -3
Query: 748 LGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
L S GA VI SRK + + + S+ G V + C V + + + G
Sbjct: 79 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHP 138
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVK-RGGGSIVFISS 395
+I+ + W I D+ + + + E +L+K + G + + I++
Sbjct: 139 NIVINNAAGNFISPTER-LSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITT 197
Query: 394 IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAG 215
I A + + +K + ++K++A E +R N + PG + TK A + +
Sbjct: 198 IYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGT 257
Query: 214 AEKSL-SNVPLKRFGRPEEIAGAVAFLASDDASYITGETVVVAGG 83
EK + +P R G EE+A AFL S AS++ G + GG
Sbjct: 258 FEKEMIGRIPCGRLGTVEELANLAAFLCSGYASWVNGAVIKFDGG 302
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLF----EV 596
A A+ L S G ++++ SR E + + + ++ VE + VA+ R ++ E
Sbjct: 82 AYAEELASRGLNIILISRNEEKLQVVAKDI-ADTYKVETDII-VADFSSGREIYLPIREA 139
Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
K G+ + +++++WD I +VN+ ++ L+ P +V+R G
Sbjct: 140 LKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVERKKG 198
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
+IV ISS + +PT L A+ SK L ++A+ E + I V + P V T +
Sbjct: 199 AIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLF----EV 596
A A+ L S G ++++ SR E + + + ++ VE + VA+ R ++ E
Sbjct: 61 AYAEELASRGLNIILISRNEEKLQVVAKDI-ADTYKVETDII-VADFSSGREIYLPIREA 118
Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
K G+ + +++++WD I +VN+ ++ L+ P +V+R G
Sbjct: 119 LKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVERKKG 177
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
+IV ISS + +PT L A+ SK L ++A+ E + I V + P V T +
Sbjct: 178 AIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 236
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLF----EV 596
A A+ L S G ++++ SR E + + + ++ VE + VA+ R ++ E
Sbjct: 82 AYAEELASRGLNIILISRNEEKLQVVAKDI-ADTYKVETDII-VADFSSGREIYLPIREA 139
Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
K G+ + +++++WD I +VN+ ++ L+ P +V+R G
Sbjct: 140 LKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVERKKG 198
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
+IV ISS + +PT L A+ SK L ++A+ E + I V + P V T +
Sbjct: 199 AIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLF----EV 596
A A+ L S G ++++ SR E + + + ++ VE + VA+ R ++ E
Sbjct: 61 AYAEELASRGLNIILISRNEEKLQVVAKDI-ADTYKVETDII-VADFSSGREIYLPIREA 118
Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
K G+ + +++++WD I +VN+ ++ L+ P +V+R G
Sbjct: 119 LKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVERKKG 177
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
+IV ISS + +PT L A+ SK L ++A+ E + I V + P V T +
Sbjct: 178 AIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 236
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/179 (24%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLF----EV 596
A A+ L S G ++++ SR E + + + ++ VE + VA+ R ++ E
Sbjct: 82 AYAEELASRGLNIILISRNEEKLQVVAKDI-ADTYKVETDII-VADFSSGREIYLPIREA 139
Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
K G+ + +++++WD I +VN+ ++ L+ P +V+R G
Sbjct: 140 LKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVERKKG 198
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
+IV ISS + +PT L A+ S+ L ++A+ E + I V + P V T +
Sbjct: 199 AIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/179 (24%), Positives = 83/179 (46%), Gaps = 4/179 (2%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLF----EV 596
A A+ L S G ++++ SR E + + + ++ VE + VA+ R ++ E
Sbjct: 82 AYAEELASRGLNIILISRNEEKLQVVAKDI-ADTYKVETDII-VADFSSGREIYLPIREA 139
Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
K G+ + +++++WD I +VN+ ++ L+ P +V+R G
Sbjct: 140 LKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVERKKG 198
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
+IV ISS + +PT L A+ S+ L ++A+ E + I V + P V T +
Sbjct: 199 AIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTA 257
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/179 (24%), Positives = 82/179 (45%), Gaps = 4/179 (2%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLF----EV 596
A A+ L S G ++++ SR E + + + ++ VE + VA+ R ++ E
Sbjct: 82 AYAEELASRGLNIILISRNEEKLQVVAKDI-ADTYKVETDII-VADFSSGREIYLPIREA 139
Query: 595 ATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
K G+ + +++++WD I +VN+ ++ L+ P +V+R G
Sbjct: 140 LKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVERKKG 198
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFAS 239
+IV ISS + +PT L A+ SK L ++A+ E + I V + P V +
Sbjct: 199 AIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVAASMTA 257
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 53.2 bits (122), Expect = 1e-06
Identities = 61/238 (25%), Positives = 100/238 (42%), Gaps = 12/238 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSK 584
A A+RL +GAS V+ S G+A + G V + + + +A K
Sbjct: 25 ATAERLVGQGASAVLLDLPNSG-GEA--QAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81
Query: 583 FGGVDILXXXXXXXXXXXSILDTDEQV-----WDKIFDVNVKSSW----LLAKEAYPELV 431
FG VD+ + Q + ++ DVN+ ++ L+A E
Sbjct: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141
Query: 430 KRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
+GG G I+ +S+AA++ AY SK ++G+T IA + IRV +APG+
Sbjct: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201
Query: 256 VTKFASAITNSEAGAEKSLSNVPL-KRFGRPEEIAGAVAFLASDDASYITGETVVVAG 86
T +++ E S VP R G P E A V + + ++ GE + + G
Sbjct: 202 GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 52.8 bits (121), Expect = 1e-06
Identities = 60/227 (26%), Positives = 92/227 (40%), Gaps = 13/227 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICS-RKESNVG-KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
A A+ L +GA V + E+ V KA + E + C VA+ + R F
Sbjct: 20 AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVV 79
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---VKSSWLLAKEAYPELVKRGG 419
FG +DIL +E+ W+K +N V S L + + G
Sbjct: 80 DHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEG 130
Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANETVHENIRVNCVAPGIVVTKF 245
G I+ +SS+A P Y SK ++G T+ A+A ++ +R+N + PG V T
Sbjct: 131 GIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
Query: 244 ASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAFLASDDA 122
+I E + K +K +G P IA + L DDA
Sbjct: 191 LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 52.8 bits (121), Expect = 1e-06
Identities = 60/227 (26%), Positives = 92/227 (40%), Gaps = 13/227 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICS-RKESNVG-KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
A A+ L +GA V + E+ V KA + E + C VA+ + R F
Sbjct: 20 AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVV 79
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---VKSSWLLAKEAYPELVKRGG 419
FG +DIL +E+ W+K +N V S L + + G
Sbjct: 80 DHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEG 130
Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANETVHENIRVNCVAPGIVVTKF 245
G I+ +SS+A P Y SK ++G T+ A+A ++ +R+N + PG V T
Sbjct: 131 GIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
Query: 244 ASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAFLASDDA 122
+I E + K +K +G P IA + L DDA
Sbjct: 191 LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 52.4 bits (120), Expect = 2e-06
Identities = 60/227 (26%), Positives = 92/227 (40%), Gaps = 13/227 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICS-RKESNVG-KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
A A+ L +GA V + E+ V KA + E + C VA+ + R F
Sbjct: 20 AFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCDVADQQQLRDTFRKVV 79
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---VKSSWLLAKEAYPELVKRGG 419
FG +DIL +E+ W+K +N V S L + + G
Sbjct: 80 DHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEG 130
Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANETVHENIRVNCVAPGIVVTKF 245
G I+ +SS+A P Y SK ++G T+ A+A ++ +R+N + PG V T
Sbjct: 131 GIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
Query: 244 ASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAFLASDDA 122
+I E + K +K +G P IA + L DDA
Sbjct: 191 LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 52.4 bits (120), Expect = 2e-06
Identities = 60/227 (26%), Positives = 92/227 (40%), Gaps = 13/227 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICS-RKESNVG-KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
A A+ L +GA V + E+ V KA + E + C VA+ + R F
Sbjct: 20 AFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCDVADQQQLRDTFRKVV 79
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---VKSSWLLAKEAYPELVKRGG 419
FG +DIL +E+ W+K +N V S L + + G
Sbjct: 80 DHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEG 130
Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK--AIANETVHENIRVNCVAPGIVVTKF 245
G I+ +SS+A P Y SK ++G T+ A+A ++ +R+N + PG V T
Sbjct: 131 GIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
Query: 244 ASAITNSEAGAE----KSLSNVPLKRFG--RPEEIAGAVAFLASDDA 122
+I E + K +K +G P IA + L DDA
Sbjct: 191 LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/142 (25%), Positives = 62/142 (43%)
Frame = -3
Query: 691 KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTD 512
K V+ +R G V + + E ++ + A FG +D++ +D
Sbjct: 57 KVVEEIRRRG---GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISD 113
Query: 511 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 332
E WD I V+++ S+ + + A+ + K+ G I+ SS + Y +K LL
Sbjct: 114 ED-WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLL 172
Query: 331 GLTKAIANETVHENIRVNCVAP 266
GL ++A E NI N +AP
Sbjct: 173 GLANSLAIEGRKSNIHCNTIAP 194
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/142 (25%), Positives = 62/142 (43%)
Frame = -3
Query: 691 KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTD 512
K V+ +R G V + + E ++ + A FG +D++ +D
Sbjct: 57 KVVEEIRRRG---GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISD 113
Query: 511 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 332
E WD I V+++ S+ + + A+ + K+ G I+ SS + Y +K LL
Sbjct: 114 ED-WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLL 172
Query: 331 GLTKAIANETVHENIRVNCVAP 266
GL ++A E NI N +AP
Sbjct: 173 GLANSLAIEGRKSNIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/142 (25%), Positives = 62/142 (43%)
Frame = -3
Query: 691 KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTD 512
K V+ +R G V + + E ++ + A FG +D++ +D
Sbjct: 57 KVVEEIRRRG---GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISD 113
Query: 511 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 332
E WD I V+++ S+ + + A+ + K+ G I+ SS + Y +K LL
Sbjct: 114 ED-WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLL 172
Query: 331 GLTKAIANETVHENIRVNCVAP 266
GL ++A E NI N +AP
Sbjct: 173 GLANSLAIEGRKSNIHCNTIAP 194
>AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens
cDNA FLJ13960 fis, clone Y79AA1001233, weakly similar to
ESTRADIOL 17 BETA-DEHYDROGENASE 1 (EC 1.1.1.62). ).
Length = 219
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/95 (32%), Positives = 46/95 (48%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+FD N + L K P + +R G IV ISS+ Q Y SK L G +++
Sbjct: 18 VFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESL 77
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNSEAGAE 209
A + + NI ++ V PG VVT+F + + AE
Sbjct: 78 AIQLLQFNIFISLVEPGPVVTEFEGKLLAQVSMAE 112
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/95 (32%), Positives = 46/95 (48%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+FD N + L K P + +R G IV ISS+ Q Y SK L G +++
Sbjct: 110 VFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESL 169
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNSEAGAE 209
A + + NI ++ V PG VVT+F + + AE
Sbjct: 170 AIQLLQFNIFISLVEPGPVVTEFEGKLLAQVSMAE 204
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/170 (25%), Positives = 64/170 (37%), Gaps = 3/170 (1%)
Frame = -3
Query: 751 RLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
RLGS V+ KE N + + V C + E R+ + + G V
Sbjct: 62 RLGS--VLVLWDINKEGNEETCKMAREAGATRVRAYTCDCSQKEGVYRVADQVKKEIGDV 119
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSI 392
IL LD +++ +K FDVN K+ K P ++ G +V ISS
Sbjct: 120 SILINNAGIVTGKK-FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSS 178
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETV---HENIRVNCVAPGIVVT 251
A L Y SK G +++ ET + I+ V P + T
Sbjct: 179 AGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKT 228
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 47.6 bits (108), Expect = 5e-05
Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Frame = -3
Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSK- 584
AK + GA +V+C R + + ++ L + T V+ ++ + VA +
Sbjct: 69 AKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAE 128
Query: 583 ----FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
FG VDIL I+DT V ++ + N L K P ++KR G
Sbjct: 129 ILQCFGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQG 187
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-S 239
IV ISSI AY SK + E I V ++PG + T + +
Sbjct: 188 HIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVN 247
Query: 238 AIT 230
AIT
Sbjct: 248 AIT 250
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 47.6 bits (108), Expect = 5e-05
Identities = 43/170 (25%), Positives = 64/170 (37%), Gaps = 3/170 (1%)
Frame = -3
Query: 751 RLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
RLGS V+ KE N + + V C + E R+ + + G V
Sbjct: 62 RLGS--VLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDV 119
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSI 392
IL LD +++ +K FDVN K+ K P ++ G +V ISS
Sbjct: 120 SILINNAGIVTGKK-FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSS 178
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETV---HENIRVNCVAPGIVVT 251
A L Y SK G +++ ET + I+ V P + T
Sbjct: 179 AGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKT 228
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 47.6 bits (108), Expect = 5e-05
Identities = 43/170 (25%), Positives = 64/170 (37%), Gaps = 3/170 (1%)
Frame = -3
Query: 751 RLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
RLGS V+ KE N + + V C + E R+ + + G V
Sbjct: 62 RLGS--VLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDV 119
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSI 392
IL LD +++ +K FDVN K+ K P ++ G +V ISS
Sbjct: 120 SILINNAGIVTGKK-FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSS 178
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETV---HENIRVNCVAPGIVVT 251
A L Y SK G +++ ET + I+ V P + T
Sbjct: 179 AGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKT 228
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 47.6 bits (108), Expect = 5e-05
Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 7/202 (3%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFE-VATSK 584
IA +L GA+V I R + Q +S G VVC + R LFE V +
Sbjct: 23 IALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQ 82
Query: 583 FGGVDILXXXXXX------XXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 422
G +D+L + +T +WD I +V ++ + + +V G
Sbjct: 83 QGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAG 142
Query: 421 GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
G IV ISS + Q + YGV K L A+E + + PGIV T+
Sbjct: 143 QGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTE-- 199
Query: 241 SAITNSEAGAEKSLSNVPLKRF 176
+ E+ L + LK+F
Sbjct: 200 --LLKEHMAKEEVLQDPVLKQF 219
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 47.6 bits (108), Expect = 5e-05
Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 7/202 (3%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFE-VATSK 584
IA +L GA+V I R + Q +S G VVC + R LFE V +
Sbjct: 23 IALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQ 82
Query: 583 FGGVDILXXXXXX------XXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 422
G +D+L + +T +WD I +V ++ + + +V G
Sbjct: 83 QGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAG 142
Query: 421 GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
G IV ISS + Q + YGV K L A+E + + PGIV T+
Sbjct: 143 QGLIVVISSPGSLQYMFNV-LYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTE-- 199
Query: 241 SAITNSEAGAEKSLSNVPLKRF 176
+ E+ L + LK+F
Sbjct: 200 --LLKEHMAKEEVLQDPVLKQF 219
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 47.6 bits (108), Expect = 5e-05
Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Frame = -3
Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSK- 584
AK + GA +V+C R + + ++ L + T V+ ++ + VA +
Sbjct: 69 AKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAE 128
Query: 583 ----FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
FG VDIL I+DT V ++ + N L K P ++KR G
Sbjct: 129 ILQCFGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQG 187
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-S 239
IV ISSI AY SK + E I V ++PG + T + +
Sbjct: 188 HIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVN 247
Query: 238 AIT 230
AIT
Sbjct: 248 AIT 250
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 47.6 bits (108), Expect = 5e-05
Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Frame = -3
Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSK- 584
AK + GA +V+C R + + ++ L + T V+ ++ + VA +
Sbjct: 69 AKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAE 128
Query: 583 ----FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
FG VDIL I+DT V ++ + N L K P ++KR G
Sbjct: 129 ILQCFGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQG 187
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-S 239
IV ISSI AY SK + E I V ++PG + T + +
Sbjct: 188 HIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVN 247
Query: 238 AIT 230
AIT
Sbjct: 248 AIT 250
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 47.6 bits (108), Expect = 5e-05
Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Frame = -3
Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSK- 584
AK + GA +V+C R + + ++ L + T V+ ++ + VA +
Sbjct: 54 AKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAE 113
Query: 583 ----FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
FG VDIL I+DT V ++ + N L K P ++KR G
Sbjct: 114 ILQCFGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQG 172
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-S 239
IV ISSI AY SK + E I V ++PG + T + +
Sbjct: 173 HIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVN 232
Query: 238 AIT 230
AIT
Sbjct: 233 AIT 235
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 47.6 bits (108), Expect = 5e-05
Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 7/202 (3%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFE-VATSK 584
IA +L GA+V I R + Q +S G VVC + R LFE V +
Sbjct: 23 IALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQ 82
Query: 583 FGGVDILXXXXXX------XXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 422
G +D+L + +T +WD I +V ++ + + +V G
Sbjct: 83 QGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAG 142
Query: 421 GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
G IV ISS + Q + YGV K L A+E + + PGIV T+
Sbjct: 143 QGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTE-- 199
Query: 241 SAITNSEAGAEKSLSNVPLKRF 176
+ E+ L + LK+F
Sbjct: 200 --LLKEHMAKEEVLQDPVLKQF 219
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 47.6 bits (108), Expect = 5e-05
Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 7/202 (3%)
Frame = -3
Query: 760 IAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFE-VATSK 584
IA +L GA+V I R + Q +S G VVC + R LFE V +
Sbjct: 23 IALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQ 82
Query: 583 FGGVDILXXXXXX------XXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRG 422
G +D+L + +T +WD I +V ++ + + +V G
Sbjct: 83 QGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAG 142
Query: 421 GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA 242
G IV ISS + Q + YGV K L A+E + + PGIV T+
Sbjct: 143 QGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTE-- 199
Query: 241 SAITNSEAGAEKSLSNVPLKRF 176
+ E+ L + LK+F
Sbjct: 200 --LLKEHMAKEEVLQDPVLKQF 219
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 47.6 bits (108), Expect = 5e-05
Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Frame = -3
Query: 757 AKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSK- 584
AK + GA +V+C R + + ++ L + T V+ ++ + VA +
Sbjct: 74 AKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAE 133
Query: 583 ----FGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 416
FG VDIL I+DT V ++ + N L K P ++KR G
Sbjct: 134 ILQCFGYVDILVNNAGISYRGT-IMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQG 192
Query: 415 SIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIVVTKFA-S 239
IV ISSI AY SK + E I V ++PG + T + +
Sbjct: 193 HIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVN 252
Query: 238 AIT 230
AIT
Sbjct: 253 AIT 255
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/165 (25%), Positives = 62/165 (37%), Gaps = 3/165 (1%)
Frame = -3
Query: 751 RLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGV 572
RLGS V+ KE N + + V C + E R+ + + G V
Sbjct: 62 RLGS--VLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDV 119
Query: 571 DILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSI 392
IL LD +++ +K FDVN K+ K P ++ G +V ISS
Sbjct: 120 SILINNAGIVTGKK-FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSS 178
Query: 391 AAYQPTEPLGAYGVSKTTLLGLTKAIANETV---HENIRVNCVAP 266
A L Y SK G +++ ET + I+ V P
Sbjct: 179 AGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCP 223
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 46.0 bits (104), Expect = 1e-04
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 7/126 (5%)
Frame = -3
Query: 502 WDKIFDVNVKSSW----LLAKEAYPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKT 341
+ ++ DVN+ ++ L+A E +GG G I+ +S+AA++ AY SK
Sbjct: 64 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 123
Query: 340 TLLGLTKAIANETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVPL-KRFGRPE 164
++G+T IA + IRV +APG+ T +++ E S VP R G P
Sbjct: 124 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPA 181
Query: 163 EIAGAV 146
E A V
Sbjct: 182 EYAHLV 187
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/175 (25%), Positives = 75/175 (42%), Gaps = 9/175 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV-------VCHVANHEHRRRL 605
AIA + +GA++VI ++ K + ++ + +E V + V + +
Sbjct: 25 AIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVDVRDEQQISAA 84
Query: 604 FEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKR 425
E A KFGG+DIL + LDT + D + +VN + ++L +K P L K
Sbjct: 85 VEKAIKKFGGIDILVNNASAISLTNT-LDTPTKRLDLMMNVNTRGTYLASKACIPYLKKS 143
Query: 424 GGGSIVFISSIAAYQPT--EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAP 266
I+ IS P + AY ++K + +A E E I VN + P
Sbjct: 144 KVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKGE-IAVNALWP 197
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/175 (25%), Positives = 75/175 (42%), Gaps = 9/175 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV-------VCHVANHEHRRRL 605
AIA + +GA++VI ++ K + ++ + +E V + V + +
Sbjct: 25 AIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVDVRDEQQISAA 84
Query: 604 FEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKR 425
E A KFGG+DIL + LDT + D + +VN + ++L +K P L K
Sbjct: 85 VEKAIKKFGGIDILVNNASAISLTNT-LDTPTKRLDLMMNVNTRGTYLASKACIPYLKKS 143
Query: 424 GGGSIVFISSIAAYQPT--EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAP 266
I+ IS P + AY ++K + +A E E I VN + P
Sbjct: 144 KVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKGE-IAVNALWP 197
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/175 (25%), Positives = 75/175 (42%), Gaps = 9/175 (5%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV-------VCHVANHEHRRRL 605
AIA + +GA++VI ++ K + ++ + +E V + V + +
Sbjct: 25 AIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVDVRDEQQISAA 84
Query: 604 FEVATSKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKR 425
E A KFGG+DIL + LDT + D + +VN + ++L +K P L K
Sbjct: 85 VEKAIKKFGGIDILVNNASAISLTNT-LDTPTKRLDLMMNVNTRGTYLASKACIPYLKKS 143
Query: 424 GGGSIVFISSIAAYQPT--EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAP 266
I+ IS P + AY ++K + +A E E I VN + P
Sbjct: 144 KVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKGE-IAVNALWP 197
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 188
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 188
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 188
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 188
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 188
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = -3
Query: 487 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 308
+VN + L K P L++ G IV + S A P LGAYG SK + L +
Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248
Query: 307 ETVHENIRVNCVAPGIVVTKFASAITNSEAGAEKSLSNVP 188
E + ++V+ + PG T+ + E + L+N+P
Sbjct: 249 ELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLP 288
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 40.7 bits (91), Expect = 0.006
Identities = 16/47 (34%), Positives = 33/47 (70%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA 386
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 40.7 bits (91), Expect = 0.006
Identities = 16/47 (34%), Positives = 33/47 (70%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA 386
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 40.7 bits (91), Expect = 0.006
Identities = 16/47 (34%), Positives = 33/47 (70%)
Frame = -3
Query: 526 ILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAA 386
+LD +E+ WD ++NV+S +L+ K P+++ + G+I+ +SS+A+
Sbjct: 90 VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/90 (27%), Positives = 44/90 (48%)
Frame = -3
Query: 511 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 332
+ V K+ ++N+ S + + P +V+R G+I+ ISS + P L Y +KT +
Sbjct: 151 DNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVD 210
Query: 331 GLTKAIANETVHENIRVNCVAPGIVVTKFA 242
++ + E + + V V P V TK A
Sbjct: 211 FFSQCLHEEYRSKGVFVQSVLPYFVATKLA 240
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/90 (27%), Positives = 44/90 (48%)
Frame = -3
Query: 511 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 332
+ V K+ ++N+ S + + P +V+R G+I+ ISS + P L Y +KT +
Sbjct: 151 DNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVD 210
Query: 331 GLTKAIANETVHENIRVNCVAPGIVVTKFA 242
++ + E + + V V P V TK A
Sbjct: 211 FFSQCLHEEYRSKGVFVQSVLPYFVATKLA 240
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/90 (27%), Positives = 44/90 (48%)
Frame = -3
Query: 511 EQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLL 332
+ V K+ ++N+ S + + P +V+R G+I+ ISS + P L Y +KT +
Sbjct: 16 DNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVD 75
Query: 331 GLTKAIANETVHENIRVNCVAPGIVVTKFA 242
++ + E + + V V P V TK A
Sbjct: 76 FFSQCLHEEYRSKGVFVQSVLPYFVATKLA 105
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 37.1 bits (82), Expect = 0.069
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 2/154 (1%)
Frame = -3
Query: 736 GASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSKFGGVDILX 560
G+ +V+ + E+ + K V + R G V + +A+ E + + A K GG+D L
Sbjct: 53 GSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLV 112
Query: 559 XXXXXXXXXXSILDTDEQV-WDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAY 383
+ + + W + VN S L A P L GS+V +SS+
Sbjct: 113 LNHIGGAPAGTRARSPQATRW--LMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGR 169
Query: 382 QPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 281
PT Y +K L G ++ E +++ V
Sbjct: 170 VPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 37.1 bits (82), Expect = 0.069
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 2/154 (1%)
Frame = -3
Query: 736 GASVVICSRKESNVGKAVQSLRSEGIT-VEGVVCHVANHEHRRRLFEVATSKFGGVDILX 560
G+ +V+ + E+ + K V + R G V + +A+ E + + A K GG+D L
Sbjct: 53 GSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLV 112
Query: 559 XXXXXXXXXXSILDTDEQV-WDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAY 383
+ + + W + VN S L A P L GS+V +SS+
Sbjct: 113 LNHIGGAPAGTRARSPQATRW--LMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGR 169
Query: 382 QPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 281
PT Y +K L G ++ E +++ V
Sbjct: 170 VPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.091
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 256 VTKFASAITNSEAGAEKSLSNVP 188
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.091
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 256 VTKFASAITNSEAGAEKSLSNVP 188
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.091
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 256 VTKFASAITNSEAGAEKSLSNVP 188
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.091
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 256 VTKFASAITNSEAGAEKSLSNVP 188
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.091
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 256 VTKFASAITNSEAGAEKSLSNVP 188
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.091
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G +V +SS+ P E L +YG SK + + + E I+V + PG
Sbjct: 206 LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGF 265
Query: 256 VTKFASAITNSEAGAEKSLSNVP 188
+T A E + L ++P
Sbjct: 266 LTNIAGTSDKWEKLEKDILDHLP 288
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 35.9 bits (79), Expect = 0.16
Identities = 40/156 (25%), Positives = 63/156 (40%), Gaps = 5/156 (3%)
Frame = -3
Query: 763 AIAKRLGSEGASVVICS-RKESNVG-KAVQSLRSEGITVEGVVCHVANHEHRRRLFEVAT 590
A A+ L +GA V + E+ V KA + E + C VA+ + R F
Sbjct: 20 AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVV 79
Query: 589 SKFGGVDILXXXXXXXXXXXSILDTDEQVWDKIFDVN---VKSSWLLAKEAYPELVKRGG 419
FG +DIL +++ W+K +N V S L + + G
Sbjct: 80 DHFGRLDILVNNAGV---------NNKKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEG 130
Query: 418 GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIA 311
G I+ +SS+A P Y SK ++G T++ A
Sbjct: 131 GIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNS 224
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNS 224
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNS 224
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNS 224
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNS 224
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNS 224
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/90 (23%), Positives = 40/90 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + + P++ +RG G ++ S+ Y SK L GL +++
Sbjct: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAITNS 224
A + + ++ + G V T F + S
Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGS 200
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 33.5 bits (73), Expect = 0.85
Identities = 24/79 (30%), Positives = 40/79 (50%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G ++ I+S+ G Y VSK L + ++ + H IRV+ V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGF- 207
Query: 256 VTKFASAITNSEAGAEKSL 200
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 33.5 bits (73), Expect = 0.85
Identities = 24/79 (30%), Positives = 40/79 (50%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G ++ I+S+ G Y VSK L + ++ + H IRV+ V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGF- 207
Query: 256 VTKFASAITNSEAGAEKSL 200
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 33.5 bits (73), Expect = 0.85
Identities = 24/79 (30%), Positives = 40/79 (50%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G ++ I+S+ G Y VSK L + ++ + H IRV+ V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGF- 207
Query: 256 VTKFASAITNSEAGAEKSL 200
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/68 (25%), Positives = 31/68 (45%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LVK+ G ++ +SS+ G Y SK + G ++ + + V+C+ PG+
Sbjct: 151 LVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209
Query: 256 VTKFASAI 233
T A +
Sbjct: 210 KTNLADPV 217
>M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase protein.
Length = 214
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/87 (22%), Positives = 39/87 (44%)
Frame = -3
Query: 493 IFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 314
+ DVNV + + ++ P++ + G G ++ S+ Y SK L GL +++
Sbjct: 108 VLDVNVVGTVRVLQDFLPDMKRPGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESL 167
Query: 313 ANETVHENIRVNCVAPGIVVTKFASAI 233
A + + V+ + G V T F +
Sbjct: 168 AVLLLPFGVHVSLIECGPVDTAFMQKV 194
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 32.3 bits (70), Expect = 2.0
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LV+R G IV +SSI + +G Y VSK + + + E H ++++ V PG
Sbjct: 151 LVRRARGRIVNVSSILG-RVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGY- 208
Query: 256 VTKFASAITNSEAGAEK 206
F + +TN E+
Sbjct: 209 ---FRTGMTNMTQSLER 222
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 32.3 bits (70), Expect = 2.0
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LV+R G IV +SSI + +G Y VSK + + + E H ++++ V PG
Sbjct: 151 LVRRARGRIVNVSSILG-RVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGY- 208
Query: 256 VTKFASAITNSEAGAEK 206
F + +TN E+
Sbjct: 209 ---FRTGMTNMTQSLER 222
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 32.3 bits (70), Expect = 2.0
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
LV+R G IV +SSI + +G Y VSK + + + E H ++++ V PG
Sbjct: 151 LVRRARGRIVNVSSILG-RVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGY- 208
Query: 256 VTKFASAITNSEAGAEK 206
F + +TN E+
Sbjct: 209 ---FRTGMTNMTQSLER 222
>Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein.
Length = 3570
Score = 31.9 bits (69), Expect = 2.6
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Frame = +3
Query: 483 TSNILSQTCSSVSKIEATAGLTAAFDT-RISTPPNLLVATSNNRLLCS*LAT*QTTP--S 653
T+ IL++ ++ + E+T T R + PP +L T+ + S AT ++P +
Sbjct: 1107 TTWILTELTTTATTTESTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTA 1166
Query: 654 TVMPSLRRLCTAFPTLLS 707
T +P+LR T PT S
Sbjct: 1167 TALPALRSTATT-PTATS 1183
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 31.1 bits (67), Expect = 4.5
Identities = 23/79 (29%), Positives = 39/79 (49%)
Frame = -3
Query: 436 LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVAPGIV 257
L+++ G ++ I+S+ G Y VSK L + ++ + H IR + V PG
Sbjct: 150 LLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRESIVEPGF- 207
Query: 256 VTKFASAITNSEAGAEKSL 200
F + +TN E+ EK+L
Sbjct: 208 ---FRTPVTNLES-LEKTL 222
>X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein.
Length = 1354
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +2
Query: 143 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 322
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 162 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 221
>L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase
protein.
Length = 1354
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +2
Query: 143 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 322
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 162 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 221
>BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) protein.
Length = 1356
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +2
Query: 143 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 322
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 164 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 223
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 30.7 bits (66), Expect = 6.0
Identities = 29/119 (24%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Frame = -3
Query: 634 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXSILDTDEQV-WDKIFDVNVKSSWLL 458
+A+ E + + A K GG+D L + + + W + VN S L
Sbjct: 1 MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRW--LMQVNFVSYVQL 58
Query: 457 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 281
A P L GS+V +SS+ PT Y +K L G ++ E +++ V
Sbjct: 59 TSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
>AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial
growth factor receptor 2 protein.
Length = 1356
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +2
Query: 143 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 322
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 164 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 223
>AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein.
Length = 1356
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +2
Query: 143 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 322
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 164 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 223
>AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) variant
protein.
Length = 1451
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/60 (25%), Positives = 23/60 (38%)
Frame = +2
Query: 143 RYGTSNFFWSPESFQWDIR*ALLRPSLGVCYRGCKLCDDDPGSDAVHSDVLVYCFVGYRL 322
RY F WD + PS + Y G C+ ++ S + + VGYR+
Sbjct: 259 RYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRI 318
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,708,040
Number of Sequences: 237096
Number of extensions: 2714251
Number of successful extensions: 8185
Number of sequences better than 10.0: 165
Number of HSP's better than 10.0 without gapping: 7552
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8101
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9199990470
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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