Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P07_F_C15
(651 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 92 1e-18
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 92 1e-18
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 92 1e-18
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 92 1e-18
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 92 1e-18
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 89 2e-17
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 79 2e-14
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 79 2e-14
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 79 2e-14
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 79 2e-14
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 79 2e-14
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 79 2e-14
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 74 4e-13
S61298-1|AAD13927.1| 21|Homo sapiens HEXA protein. 34 0.51
AF222342-1|AAF33793.1| 101|Homo sapiens T-cell specific surface... 30 8.2
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 92.3 bits (219), Expect = 1e-18
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Frame = +1
Query: 145 AIWPRPQ-MQSIEIPY------YKFDSDVLEIKVIEHDCPILSNAVQRSLAVLRDMLRIA 303
A+WP PQ Q+ + Y ++F DV + C +L A QR RD+L
Sbjct: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSS--AAQPGCSVLDEAFQR----YRDLL--- 72
Query: 304 SPYVNRNAPQQVLDDDTYDGPLKSLSIYLTSP-CEEYPHFGMIESYNLTIAADSTLR-SS 477
+ + + P+ L + L + + +P C + P +E+Y LTI D L S
Sbjct: 73 --FGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSE 130
Query: 478 SIWGILRGLESWTHLFHLSDNRDQLHINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
++WG LRGLE+++ L S INK E+ DFPR+PHRGLL+DTSRHY+ +S+IL
Sbjct: 131 TVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSIL 187
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 92.3 bits (219), Expect = 1e-18
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Frame = +1
Query: 145 AIWPRPQ-MQSIEIPY------YKFDSDVLEIKVIEHDCPILSNAVQRSLAVLRDMLRIA 303
A+WP PQ Q+ + Y ++F DV + C +L A QR RD+L
Sbjct: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSS--AAQPGCSVLDEAFQR----YRDLL--- 72
Query: 304 SPYVNRNAPQQVLDDDTYDGPLKSLSIYLTSP-CEEYPHFGMIESYNLTIAADSTLR-SS 477
+ + + P+ L + L + + +P C + P +E+Y LTI D L S
Sbjct: 73 --FGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSE 130
Query: 478 SIWGILRGLESWTHLFHLSDNRDQLHINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
++WG LRGLE+++ L S INK E+ DFPR+PHRGLL+DTSRHY+ +S+IL
Sbjct: 131 TVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSIL 187
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 92.3 bits (219), Expect = 1e-18
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Frame = +1
Query: 145 AIWPRPQ-MQSIEIPY------YKFDSDVLEIKVIEHDCPILSNAVQRSLAVLRDMLRIA 303
A+WP PQ Q+ + Y ++F DV + C +L A QR RD+L
Sbjct: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSS--AAQPGCSVLDEAFQR----YRDLL--- 72
Query: 304 SPYVNRNAPQQVLDDDTYDGPLKSLSIYLTSP-CEEYPHFGMIESYNLTIAADSTLR-SS 477
+ + + P+ L + L + + +P C + P +E+Y LTI D L S
Sbjct: 73 --FGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSE 130
Query: 478 SIWGILRGLESWTHLFHLSDNRDQLHINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
++WG LRGLE+++ L S INK E+ DFPR+PHRGLL+DTSRHY+ +S+IL
Sbjct: 131 TVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSIL 187
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 92.3 bits (219), Expect = 1e-18
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Frame = +1
Query: 145 AIWPRPQ-MQSIEIPY------YKFDSDVLEIKVIEHDCPILSNAVQRSLAVLRDMLRIA 303
A+WP PQ Q+ + Y ++F DV + C +L A QR RD+L
Sbjct: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSS--AAQPGCSVLDEAFQR----YRDLL--- 72
Query: 304 SPYVNRNAPQQVLDDDTYDGPLKSLSIYLTSP-CEEYPHFGMIESYNLTIAADSTLR-SS 477
+ + + P+ L + L + + +P C + P +E+Y LTI D L S
Sbjct: 73 --FGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSE 130
Query: 478 SIWGILRGLESWTHLFHLSDNRDQLHINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
++WG LRGLE+++ L S INK E+ DFPR+PHRGLL+DTSRHY+ +S+IL
Sbjct: 131 TVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSIL 187
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 92.3 bits (219), Expect = 1e-18
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Frame = +1
Query: 145 AIWPRPQ-MQSIEIPY------YKFDSDVLEIKVIEHDCPILSNAVQRSLAVLRDMLRIA 303
A+WP PQ Q+ + Y ++F DV + C +L A QR RD+L
Sbjct: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSS--AAQPGCSVLDEAFQR----YRDLL--- 72
Query: 304 SPYVNRNAPQQVLDDDTYDGPLKSLSIYLTSP-CEEYPHFGMIESYNLTIAADSTLR-SS 477
+ + + P+ L + L + + +P C + P +E+Y LTI D L S
Sbjct: 73 --FGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSE 130
Query: 478 SIWGILRGLESWTHLFHLSDNRDQLHINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
++WG LRGLE+++ L S INK E+ DFPR+PHRGLL+DTSRHY+ +S+IL
Sbjct: 131 TVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSIL 187
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 88.6 bits (210), Expect = 2e-17
Identities = 57/156 (36%), Positives = 84/156 (53%), Gaps = 2/156 (1%)
Frame = +1
Query: 190 YKFDSDVLEIKVIEHDCPILSNAVQRSLAVLRDMLRIASPYVNRNAPQQVLDDDTYDGPL 369
++F DV + C +L A QR RD+L + + + P+ L +
Sbjct: 5 FQFQYDVSS--AAQPGCSVLDEAFQR----YRDLL-----FGSGSWPRPYLTGKRHTLEK 53
Query: 370 KSLSIYLTSP-CEEYPHFGMIESYNLTIAADSTLR-SSSIWGILRGLESWTHLFHLSDNR 543
L + + +P C + P +E+Y LTI D L S ++WG LRGLE+++ L S
Sbjct: 54 NVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE- 112
Query: 544 DQLHINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
INK E+ DFPR+PHRGLL+DTSRHY+ +S+IL
Sbjct: 113 GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSIL 148
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/93 (39%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Frame = +1
Query: 376 LSIYLTSPCEEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFHLSDNRDQL 552
+SI L S C+ +P+ ESY L + + L+++ +WG LRGLE+++ L + D+
Sbjct: 129 VSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QDSYGTF 187
Query: 553 HINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
IN+ + D PR+ HRG+L+DTSRHY+ + IL
Sbjct: 188 TINESTIIDSPRFSHRGILIDTSRHYLPVKIIL 220
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/93 (39%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Frame = +1
Query: 376 LSIYLTSPCEEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFHLSDNRDQL 552
+SI L S C+ +P+ ESY L + + L+++ +WG LRGLE+++ L + D+
Sbjct: 117 VSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QDSYGTF 175
Query: 553 HINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
IN+ + D PR+ HRG+L+DTSRHY+ + IL
Sbjct: 176 TINESTIIDSPRFSHRGILIDTSRHYLPVKIIL 208
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/93 (39%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Frame = +1
Query: 376 LSIYLTSPCEEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFHLSDNRDQL 552
+SI L S C+ +P+ ESY L + + L+++ +WG LRGLE+++ L + D+
Sbjct: 145 VSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QDSYGTF 203
Query: 553 HINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
IN+ + D PR+ HRG+L+DTSRHY+ + IL
Sbjct: 204 TINESTIIDSPRFSHRGILIDTSRHYLPVKIIL 236
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/93 (39%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Frame = +1
Query: 376 LSIYLTSPCEEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFHLSDNRDQL 552
+SI L S C+ +P+ ESY L + + L+++ +WG LRGLE+++ L + D+
Sbjct: 129 VSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QDSYGTF 187
Query: 553 HINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
IN+ + D PR+ HRG+L+DTSRHY+ + IL
Sbjct: 188 TINESTIIDSPRFSHRGILIDTSRHYLPVKIIL 220
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/93 (39%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Frame = +1
Query: 376 LSIYLTSPCEEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFHLSDNRDQL 552
+SI L S C+ +P+ ESY L + + L+++ +WG LRGLE+++ L + D+
Sbjct: 129 VSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QDSYGTF 187
Query: 553 HINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
IN+ + D PR+ HRG+L+DTSRHY+ + IL
Sbjct: 188 TINESTIIDSPRFSHRGILIDTSRHYLPVKIIL 220
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/93 (39%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Frame = +1
Query: 376 LSIYLTSPCEEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFHLSDNRDQL 552
+SI L S C+ +P+ ESY L + + L+++ +WG LRGLE+++ L + D+
Sbjct: 129 VSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QDSYGTF 187
Query: 553 HINKGEVHDFPRYPHRGLLVDTSRHYISMSNIL 651
IN+ + D PR+ HRG+L+DTSRHY+ + IL
Sbjct: 188 TINESTIIDSPRFSHRGILIDTSRHYLPVKIIL 220
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 74.1 bits (174), Expect = 4e-13
Identities = 34/62 (54%), Positives = 45/62 (72%)
Frame = +1
Query: 466 LRSSSIWGILRGLESWTHLFHLSDNRDQLHINKGEVHDFPRYPHRGLLVDTSRHYISMSN 645
L S ++WG LRGLE+++ L S INK E+ DFPR+PHRGLL+DTSRHY+ +S+
Sbjct: 7 LLSETVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSS 65
Query: 646 IL 651
IL
Sbjct: 66 IL 67
>S61298-1|AAD13927.1| 21|Homo sapiens HEXA protein.
Length = 21
Score = 33.9 bits (74), Expect = 0.51
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 556 INKGEVHDFPRYPHRGL 606
INK E+ DFPR+PH+GL
Sbjct: 5 INKTEIEDFPRFPHQGL 21
>AF222342-1|AAF33793.1| 101|Homo sapiens T-cell specific surface
glycoprotein CD28 isoform 2 protein.
Length = 101
Score = 29.9 bits (64), Expect = 8.2
Identities = 14/36 (38%), Positives = 18/36 (50%)
Frame = +1
Query: 46 MFRLFLYLNILGAFLVTGLHIVEPGPEYPAAKGAIW 153
M RL L LN+ + VTG H+ P P +P W
Sbjct: 1 MLRLLLALNLFPSIQVTGKHLC-PSPLFPGPSKPFW 35
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,422,509
Number of Sequences: 237096
Number of extensions: 1875453
Number of successful extensions: 4499
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4361
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4474
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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