Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P06_F_N05
(653 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q177S6 Cluster: Dihydroorotate dehydrogenase; n=7; Coel... 205 8e-52
UniRef50_Q02127 Cluster: Dihydroorotate dehydrogenase, mitochond... 169 4e-41
UniRef50_Q75XR0 Cluster: Dihydroorotate dehydrogenase; n=4; cell... 163 2e-39
UniRef50_P32748 Cluster: Dihydroorotate dehydrogenase, mitochond... 162 8e-39
UniRef50_A7QV01 Cluster: Chromosome undetermined scaffold_183, w... 159 4e-38
UniRef50_A7IBC2 Cluster: Dihydroorotate oxidase; n=2; Alphaprote... 151 1e-35
UniRef50_Q5UF20 Cluster: Predicted dihydroorotate dehydrogenase;... 150 3e-35
UniRef50_Q8MXD1 Cluster: Dihydroorotate dehydrogenase; n=1; Toxo... 149 6e-35
UniRef50_P32747 Cluster: Dihydroorotate dehydrogenase, mitochond... 136 7e-35
UniRef50_Q6SZS6 Cluster: Dihydroorotate dehydrogenase, mitochond... 147 2e-34
UniRef50_Q5DD85 Cluster: SJCHGC02326 protein; n=2; Schistosoma j... 147 2e-34
UniRef50_Q75CE1 Cluster: Dihydroorotate dehydrogenase, mitochond... 143 3e-33
UniRef50_Q4FP58 Cluster: Dihydroorotate dehydrogenase; n=3; Bact... 140 3e-32
UniRef50_O01815 Cluster: Putative uncharacterized protein W02D3.... 140 4e-32
UniRef50_Q0GF37 Cluster: Dihydroorotate dehydrogenase; n=2; Usti... 140 4e-32
UniRef50_P32746 Cluster: Dihydroorotate dehydrogenase, mitochond... 139 5e-32
UniRef50_Q1GGD3 Cluster: Dihydroorotate dehydrogenase; n=24; Alp... 136 3e-31
UniRef50_A7AUQ8 Cluster: Dihydroorotate dehydrogenase; n=1; Babe... 136 4e-31
UniRef50_Q2GEM2 Cluster: Dihydroorotate dehydrogenase; n=1; Neor... 135 8e-31
UniRef50_Q5KK62 Cluster: Dihydroorotate dehydrogenase, mitochond... 134 1e-30
UniRef50_Q8G2K8 Cluster: Dihydroorotate dehydrogenase; n=29; cel... 133 3e-30
UniRef50_P28294 Cluster: Dihydroorotate dehydrogenase; n=8; cell... 133 3e-30
UniRef50_Q4UDM3 Cluster: Dihydroorotate dehydrogenase, mitochond... 128 1e-28
UniRef50_Q5FTP3 Cluster: Dihydroorotate dehydrogenase; n=3; Acet... 126 5e-28
UniRef50_Q7RLG4 Cluster: Dihydroorotate dehydrogenase, putative;... 124 2e-27
UniRef50_Q6G4F7 Cluster: Dihydroorotate dehydrogenase; n=3; Rhiz... 122 1e-26
UniRef50_A5K1N1 Cluster: Dihydroorotate dehydrogenase, mitochond... 121 2e-26
UniRef50_Q5PBF6 Cluster: Dihydroorotate dehydrogenase; n=12; Ric... 120 2e-26
UniRef50_A2VBP6 Cluster: Dihydroorotate dehydrogenase, mitochond... 120 2e-26
UniRef50_Q83GM4 Cluster: Dihydroorotate oxidase; n=2; Tropheryma... 116 4e-25
UniRef50_Q0RAG2 Cluster: Dihydroorotate dehydrogenase; n=1; Wolb... 116 5e-25
UniRef50_A5EV79 Cluster: Dihydroorotate dehydrogenase; n=1; Dich... 116 5e-25
UniRef50_Q9PAE7 Cluster: Dihydroorotate dehydrogenase; n=155; Ba... 116 5e-25
UniRef50_Q0LH17 Cluster: Dihydroorotate dehydrogenase; n=1; Herp... 115 9e-25
UniRef50_A5AEM5 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-24
UniRef50_Q08210 Cluster: Dihydroorotate dehydrogenase homolog, m... 114 2e-24
UniRef50_A5UX75 Cluster: Dihydroorotate oxidase; n=1; Roseiflexu... 114 2e-24
UniRef50_Q6AE78 Cluster: Dihydroorotate dehydrogenase; n=6; Acti... 110 2e-23
UniRef50_Q62K45 Cluster: Dihydroorotate dehydrogenase; n=38; cel... 110 2e-23
UniRef50_A7CXZ7 Cluster: Dihydroorotate oxidase; n=1; Opitutacea... 109 4e-23
UniRef50_Q8EYC6 Cluster: Dihydroorotate dehydrogenase; n=4; Lept... 108 1e-22
UniRef50_A2QCB1 Cluster: Catalytic activity:; n=9; Pezizomycotin... 107 3e-22
UniRef50_Q2YWG7 Cluster: Dihydroorotate dehydrogenase; n=16; Sta... 103 4e-21
UniRef50_P57443 Cluster: Dihydroorotate dehydrogenase; n=3; Prot... 103 5e-21
UniRef50_A7BDH3 Cluster: Putative uncharacterized protein; n=1; ... 102 7e-21
UniRef50_Q1GVC1 Cluster: Dihydroorotate dehydrogenase; n=10; Alp... 101 2e-20
UniRef50_Q5X496 Cluster: Dihydroorotate dehydrogenase; n=5; Legi... 100 3e-20
UniRef50_P45477 Cluster: Dihydroorotate dehydrogenase; n=13; Hae... 99 5e-20
UniRef50_A6Q8G0 Cluster: Dihydroorotate dehydrogenase; n=4; Epsi... 100 6e-20
UniRef50_Q7U3U2 Cluster: Dihydroorotate dehydrogenase; n=25; Cya... 100 6e-20
UniRef50_Q6D456 Cluster: Dihydroorotate dehydrogenase; n=4; Ente... 99 8e-20
UniRef50_Q0CXV7 Cluster: Putative uncharacterized protein; n=1; ... 97 2e-19
UniRef50_Q8D9G5 Cluster: Dihydroorotate dehydrogenase; n=56; Pro... 97 2e-19
UniRef50_Q2S001 Cluster: Dihydroorotate oxidase; n=1; Salinibact... 97 3e-19
UniRef50_A3J5I9 Cluster: Dihydroorotate dehydrogenase; n=19; Bac... 97 4e-19
UniRef50_Q0U3U0 Cluster: Putative uncharacterized protein; n=2; ... 97 4e-19
UniRef50_Q9RX14 Cluster: Dihydroorotate dehydrogenase; n=4; Bact... 95 1e-18
UniRef50_Q7S895 Cluster: Putative uncharacterized protein NCU065... 95 1e-18
UniRef50_A0H696 Cluster: Dihydroorotate oxidase; n=2; Chloroflex... 94 3e-18
UniRef50_P74782 Cluster: Dihydroorotate dehydrogenase; n=12; Bac... 93 4e-18
UniRef50_Q8FTC6 Cluster: Dihydroorotate dehydrogenase; n=35; Bac... 93 4e-18
UniRef50_Q5YVM8 Cluster: Dihydroorotate dehydrogenase; n=6; Bact... 91 3e-17
UniRef50_A7GYB2 Cluster: Dihydroorotate oxidase; n=7; Campylobac... 87 3e-16
UniRef50_Q64UC1 Cluster: Dihydroorotate dehydrogenase; n=3; Bact... 87 3e-16
UniRef50_Q2H299 Cluster: Putative uncharacterized protein; n=1; ... 87 5e-16
UniRef50_Q5UYF1 Cluster: Dihydroorotate dehydrogenase; n=7; Halo... 82 1e-14
UniRef50_O25655 Cluster: Dihydroorotate dehydrogenase; n=15; Cam... 81 2e-14
UniRef50_A3ZNL9 Cluster: Dihydroorotate dehydrogenase; n=2; Plan... 78 2e-13
UniRef50_Q8G505 Cluster: Dihydroorotate dehydrogenase-like prote... 77 4e-13
UniRef50_Q2IVE7 Cluster: Dihydroorotate oxidase; n=1; Rhodopseud... 71 2e-11
UniRef50_Q6MPX3 Cluster: PyrD protein; n=1; Bdellovibrio bacteri... 70 6e-11
UniRef50_A3H775 Cluster: Dihydroorotate oxidase; n=1; Caldivirga... 60 3e-08
UniRef50_Q8ZTG4 Cluster: Dihydroorotate dehydrogenase; n=4; Pyro... 50 5e-05
UniRef50_A0DS83 Cluster: Chromosome undetermined scaffold_61, wh... 45 0.002
UniRef50_Q73P17 Cluster: Dihydroorotate dehydrogenase/oxidoreduc... 39 0.12
UniRef50_Q11LN4 Cluster: Flagellin-like; n=6; Rhizobiales|Rep: F... 39 0.12
UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family pro... 36 0.85
UniRef50_A5NSG9 Cluster: Dihydroorotate dehydrogenase family pro... 36 1.1
UniRef50_Q4DGY9 Cluster: Dihydroorotate dehydrogenase, putative;... 36 1.1
UniRef50_Q2KCJ6 Cluster: Sensor protein; n=2; Rhizobium|Rep: Sen... 35 1.5
UniRef50_A4BME3 Cluster: Putative uncharacterized protein; n=1; ... 35 1.5
UniRef50_Q7S1F3 Cluster: Predicted protein; n=4; Pezizomycotina|... 35 2.0
UniRef50_Q47741 Cluster: Dihydroorotate dehydrogenase B, catalyt... 35 2.0
UniRef50_UPI00015BD53C Cluster: UPI00015BD53C related cluster; n... 34 2.6
UniRef50_A4ECL7 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6
UniRef50_A0R4B8 Cluster: Transcription regulator; n=1; Mycobacte... 34 2.6
UniRef50_A4R249 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6
UniRef50_Q2BA70 Cluster: Dihydroorotate dehydrogenase; n=1; Baci... 34 3.4
UniRef50_Q1IUQ6 Cluster: Dihydroorotate dehydrogenase family pro... 33 4.5
UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DS... 33 4.5
UniRef50_UPI0000D557BD Cluster: PREDICTED: similar to CG8831-PA;... 33 6.0
UniRef50_UPI000038D93A Cluster: COG0642: Signal transduction his... 33 6.0
UniRef50_Q24CB5 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0
UniRef50_Q4PE03 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0
UniRef50_UPI0000DAE5CB Cluster: hypothetical protein Rgryl_01000... 33 7.9
UniRef50_Q14151 Cluster: Scaffold attachment factor B2; n=25; Ma... 33 7.9
UniRef50_Q9YFI6 Cluster: Dihydroorotate dehydrogenase; n=3; Desu... 33 7.9
>UniRef50_Q177S6 Cluster: Dihydroorotate dehydrogenase; n=7;
Coelomata|Rep: Dihydroorotate dehydrogenase - Aedes
aegypti (Yellowfever mosquito)
Length = 395
Score = 205 bits (500), Expect = 8e-52
Identities = 96/188 (51%), Positives = 127/188 (67%)
Frame = +3
Query: 90 KIRSLCYVTXXXXXXXXXXXXKKDFNSYYENVLQPLSQYLSPEVAHRIGVAAIKHGLFPP 269
K RSL VT K +YE++ P+ + + PE AH++ V IK L P
Sbjct: 11 KFRSLVKVTSLGAVTFSAICLYKGNEKFYESIFMPIVRLIPPETAHQLAVFGIKLALVRP 70
Query: 270 DQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNP 449
+DP+ L+TR L +SNP+GIAAGFDKHG+AV GL ++GF +E+GSVTP+PQPGN
Sbjct: 71 SF-QDPETLRTRFLGMTVSNPVGIAAGFDKHGEAVAGLQRIGFGFVEIGSVTPKPQPGNQ 129
Query: 450 KPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAGKD 629
+PRVFRL ED A++NRYGFNS GHD VY++L+ + + NR +LGVNLG+NK S DA D
Sbjct: 130 RPRVFRLNEDKAIVNRYGFNSDGHDVVYERLKKMREENPNRVMLGVNLGRNKHSPDAYND 189
Query: 630 YVSGIEKF 653
Y+ GI+KF
Sbjct: 190 YIQGIKKF 197
>UniRef50_Q02127 Cluster: Dihydroorotate dehydrogenase,
mitochondrial precursor; n=35; cellular organisms|Rep:
Dihydroorotate dehydrogenase, mitochondrial precursor -
Homo sapiens (Human)
Length = 395
Score = 169 bits (412), Expect = 4e-41
Identities = 86/166 (51%), Positives = 108/166 (65%), Gaps = 4/166 (2%)
Frame = +3
Query: 159 DFNSYYENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLG 338
D Y E+++ L L PE AHR+ V GL P + +D +L+ R+L + NP+G
Sbjct: 33 DERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVG 92
Query: 339 IAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIG 518
IAAGFDKHG+AV GL K+GF +E+GSVTP+PQ GNP+PRVFRLPED AVINRYGFNS G
Sbjct: 93 IAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHG 152
Query: 519 HDEVYKKLEGIE----KAVMNRALLGVNLGKNKLSDDAGKDYVSGI 644
V +L + K + LGVNLGKNK S DA +DY G+
Sbjct: 153 LSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGV 198
>UniRef50_Q75XR0 Cluster: Dihydroorotate dehydrogenase; n=4;
cellular organisms|Rep: Dihydroorotate dehydrogenase -
Euglena gracilis
Length = 435
Score = 163 bits (397), Expect = 2e-39
Identities = 80/159 (50%), Positives = 102/159 (64%), Gaps = 1/159 (0%)
Frame = +3
Query: 177 ENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFD 356
+NV PL + L E AH + A GL P D + DP L+ + SNPLG+AAGFD
Sbjct: 59 DNVAMPLVRLLEAEAAHDCAIRAASWGLVPRDVHPDPADLEMEVWGLKFSNPLGLAAGFD 118
Query: 357 KHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYK 536
KHG+AV L+ GF +E+G+VTP PQPGNP PR+FRL +D A+INRYGFNS G V K
Sbjct: 119 KHGEAVDALLGTGFGFVEIGTVTPLPQPGNPSPRMFRLEQDRAIINRYGFNSQGLAAVRK 178
Query: 537 KLEGIEKAVMNR-ALLGVNLGKNKLSDDAGKDYVSGIEK 650
+LE + R L+GVN+GKNKL +DA DY G+ +
Sbjct: 179 RLEARQHRPAPRGGLVGVNVGKNKLQEDAAADYSKGLRE 217
>UniRef50_P32748 Cluster: Dihydroorotate dehydrogenase,
mitochondrial precursor; n=4; Sophophora|Rep:
Dihydroorotate dehydrogenase, mitochondrial precursor -
Drosophila melanogaster (Fruit fly)
Length = 405
Score = 162 bits (393), Expect = 8e-39
Identities = 84/188 (44%), Positives = 109/188 (57%)
Frame = +3
Query: 90 KIRSLCYVTXXXXXXXXXXXXKKDFNSYYENVLQPLSQYLSPEVAHRIGVAAIKHGLFPP 269
++RSL VT K+ + + + P + L E +H++ V A K+ L P
Sbjct: 18 RLRSLGIVTVGGAALVAGITAYKNQDQLFRTFVMPAVRLLPAEASHQLAVLACKYRLCPV 77
Query: 270 DQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNP 449
Q D + L T LSNP+GIAAGFDK+ +AV GL LGF IEVG+VTP Q GNP
Sbjct: 78 SQYHDDQNLHTSFFGRMLSNPIGIAAGFDKNAEAVDGLQDLGFGFIEVGTVTPAAQEGNP 137
Query: 450 KPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAGKD 629
KPRVFRL ED A+INRYGFNS GH V ++L + K ++GVNLG+NK + D
Sbjct: 138 KPRVFRLTEDKAIINRYGFNSDGHQAVLQRLRLLRKKENFNGVVGVNLGRNKTTMSPIAD 197
Query: 630 YVSGIEKF 653
YV G+ F
Sbjct: 198 YVQGVRVF 205
>UniRef50_A7QV01 Cluster: Chromosome undetermined scaffold_183,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_183, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 493
Score = 159 bits (387), Expect = 4e-38
Identities = 82/154 (53%), Positives = 102/154 (66%)
Frame = +3
Query: 183 VLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKH 362
++ P L EVAHR+ V+A GL P ++ DP IL + SNP+G+AAGFDK+
Sbjct: 146 LVNPFFALLDAEVAHRLAVSAAARGLVPREKRPDPSILGLEVWGRKFSNPVGLAAGFDKN 205
Query: 363 GDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
+AV GL+ LGF +EVGSVTP PQ GNPKPR+FRL +GA+INR GFNS G V K+L
Sbjct: 206 AEAVEGLLGLGFGFVEVGSVTPVPQEGNPKPRIFRLRHEGAIINRCGFNSEGIFAVAKRL 265
Query: 543 EGIEKAVMNRALLGVNLGKNKLSDDAGKDYVSGI 644
KA +LGVNLGKNK S+DA DYV G+
Sbjct: 266 ---GKA--GPGILGVNLGKNKTSEDAAADYVQGV 294
>UniRef50_A7IBC2 Cluster: Dihydroorotate oxidase; n=2;
Alphaproteobacteria|Rep: Dihydroorotate oxidase -
Xanthobacter sp. (strain Py2)
Length = 357
Score = 151 bits (366), Expect = 1e-35
Identities = 73/155 (47%), Positives = 101/155 (65%), Gaps = 1/155 (0%)
Frame = +3
Query: 183 VLQPLSQYLSPEVAHRIGVAAIKHGLFPP-DQNEDPKILKTRLLDYDLSNPLGIAAGFDK 359
VL+PL ++++PE AH + + +K GL P D +L TR+ D NP+G+AAGFDK
Sbjct: 6 VLKPLFRFMTPEQAHHLSIRVLKSGLVPDLSGGPDDPVLATRVWGLDFPNPVGLAAGFDK 65
Query: 360 HGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKK 539
H + L + GF +E G+VTP+PQPGNP PR+FRL ED AVINR+GFNS G +
Sbjct: 66 HCEVADALFRFGFGFVEAGTVTPRPQPGNPLPRLFRLDEDEAVINRFGFNSEGLAPFVFR 125
Query: 540 LEGIEKAVMNRALLGVNLGKNKLSDDAGKDYVSGI 644
L G +A ++G N+GKNK S+DA +DY +G+
Sbjct: 126 L-GQRRASGKHGIVGANVGKNKESEDALEDYGAGV 159
>UniRef50_Q5UF20 Cluster: Predicted dihydroorotate dehydrogenase;
n=1; uncultured alpha proteobacterium EBAC2C11|Rep:
Predicted dihydroorotate dehydrogenase - uncultured
alpha proteobacterium EBAC2C11
Length = 378
Score = 150 bits (363), Expect = 3e-35
Identities = 77/152 (50%), Positives = 100/152 (65%), Gaps = 1/152 (0%)
Frame = +3
Query: 180 NVLQPLSQYLSPEVAHRIGVAAIKHGLFP-PDQNEDPKILKTRLLDYDLSNPLGIAAGFD 356
N+L L+++L E AH+I VAA+ + + P P Q + L R+ + +NPLG+AAGFD
Sbjct: 4 NLLAKLARHLPAEAAHQIAVAALHYNVGPRPAQRQSKADLTVRIAGLEFANPLGLAAGFD 63
Query: 357 KHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYK 536
K+ G M LGF+ +EVG++TP+ QPGNPKPRVFRLPE+ AVINRYGFNS G D V K
Sbjct: 64 KNATCFNGAMGLGFAHVEVGTITPKRQPGNPKPRVFRLPEENAVINRYGFNSHGMDRVAK 123
Query: 537 KLEGIEKAVMNRALLGVNLGKNKLSDDAGKDY 632
L A +LGVN+G NK S+D DY
Sbjct: 124 NL--YATASKRVGILGVNVGANKTSNDPIDDY 153
>UniRef50_Q8MXD1 Cluster: Dihydroorotate dehydrogenase; n=1;
Toxoplasma gondii|Rep: Dihydroorotate dehydrogenase -
Toxoplasma gondii
Length = 592
Score = 149 bits (361), Expect = 6e-35
Identities = 77/171 (45%), Positives = 105/171 (61%), Gaps = 10/171 (5%)
Frame = +3
Query: 168 SYYENVLQPLSQYLS-----PEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNP 332
S+YE V L +Y S PE AH + K G P D + + L + +P
Sbjct: 184 SFYEPVTSVLFRYFSSGPLDPETAHGYTMELAKRGWLPVDYDREESALNVDINGLKFLSP 243
Query: 333 LGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNS 512
+G+AAGFDKH +A L+++GFS +EVGS+TP+PQPGNPKPR+FRL ED +VINR+GFNS
Sbjct: 244 IGLAAGFDKHAEAPAALLRMGFSFLEVGSITPKPQPGNPKPRLFRLYEDRSVINRFGFNS 303
Query: 513 IGHDEVYKKLEGIEKAVMN-----RALLGVNLGKNKLSDDAGKDYVSGIEK 650
G D +LE +A + + +LGV+LGKNK S+DA D G++K
Sbjct: 304 NGADYAQTQLEAFSEARLRDPFTAQGVLGVSLGKNKTSEDAVADLREGVKK 354
>UniRef50_P32747 Cluster: Dihydroorotate dehydrogenase,
mitochondrial precursor; n=1; Schizosaccharomyces
pombe|Rep: Dihydroorotate dehydrogenase, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 443
Score = 136 bits (328), Expect(2) = 7e-35
Identities = 59/114 (51%), Positives = 78/114 (68%)
Frame = +3
Query: 204 YLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGL 383
+ +PE +HR+ + A G+ P D+ D L + NP+G+AAGFDK DA+ GL
Sbjct: 75 FTTPEFSHRVAILAASWGITPKDRVADDPSLAVEVWGKKFCNPIGLAAGFDKQADAISGL 134
Query: 384 MKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLE 545
+ GFS +E+GSVTP+PQPGNPKPR FRL D +VINRYGFNSIGHD + K++
Sbjct: 135 LNFGFSYLEIGSVTPKPQPGNPKPRYFRLKPDLSVINRYGFNSIGHDAILAKIQ 188
Score = 34.3 bits (75), Expect(2) = 7e-35
Identities = 14/36 (38%), Positives = 24/36 (66%)
Frame = +3
Query: 546 GIEKAVMNRALLGVNLGKNKLSDDAGKDYVSGIEKF 653
G+ ++++ LG+NLGKNK ++ +DYV G+ F
Sbjct: 220 GVPRSLIPNKFLGINLGKNKNGNEI-EDYVEGVRTF 254
>UniRef50_Q6SZS6 Cluster: Dihydroorotate dehydrogenase,
mitochondrial precursor; n=9; Saccharomycetales|Rep:
Dihydroorotate dehydrogenase, mitochondrial precursor -
Kluyveromyces marxianus (Yeast) (Candida kefyr)
Length = 446
Score = 147 bits (357), Expect = 2e-34
Identities = 88/225 (39%), Positives = 120/225 (53%), Gaps = 21/225 (9%)
Frame = +3
Query: 42 FVLFTTT-MSQKKDPLKKIRSLCYVTXXXXXXXXXXXXKKDFNSYYENVLQPLSQYLSP- 215
F+ F MS K + + L Y ++ +E V P + L+P
Sbjct: 19 FIFFAKNEMSPLKAGVPGAKFLKYTVGFTLGTLAGFYLTNSRSAIHEYVSCPTVRLLTPD 78
Query: 216 -EVAHRIGVAAIKHGLFPPDQ-NEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMK 389
E H++G+ +K+GL P ++D ++L + L+NP+G AAG DK G+A+ G+
Sbjct: 79 AEAGHKLGIWLLKYGLAPRLWFDKDEELLHVNVFGKTLTNPVGCAAGLDKDGEAIDGIFA 138
Query: 390 LGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMN 569
GF +E+GSVTP PQPGNPKPR FRLP D AVINRYGFNS GHD V K L+ +N
Sbjct: 139 GGFGYVEIGSVTPLPQPGNPKPRFFRLPMDEAVINRYGFNSSGHDSVVKNLQNRVSRFIN 198
Query: 570 -----------------RALLGVNLGKNKLSDDAGKDYVSGIEKF 653
LLG+NLGKNK D+ +DY+ G+EKF
Sbjct: 199 SYFCNDINAVDNLSLYQNKLLGINLGKNKNGDEV-QDYLKGVEKF 242
>UniRef50_Q5DD85 Cluster: SJCHGC02326 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC02326 protein - Schistosoma
japonicum (Blood fluke)
Length = 385
Score = 147 bits (356), Expect = 2e-34
Identities = 71/163 (43%), Positives = 103/163 (63%), Gaps = 2/163 (1%)
Frame = +3
Query: 171 YYENVLQPLSQYL--SPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIA 344
+Y + P ++++ E AH + + A HG P LK ++ + +P+G+A
Sbjct: 30 FYRDWFLPAARFVVRDGETAHNLSLYAASHGFIPRKPRNVFPSLKCKVFGLEFDHPVGLA 89
Query: 345 AGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHD 524
AGFDK+G+A + L+ +GFS IEVG+VTP PQPGN +PR+FR E A+INR GFN+ GHD
Sbjct: 90 AGFDKNGEAFMDLLNVGFSHIEVGTVTPNPQPGNSRPRIFRWTEKNAIINRCGFNNDGHD 149
Query: 525 EVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAGKDYVSGIEKF 653
VY++L+ + R +LGVNLG N+ S D DYV+G+ KF
Sbjct: 150 TVYERLK--NRPWEGRGVLGVNLGCNRTSIDPTSDYVAGVRKF 190
>UniRef50_Q75CE1 Cluster: Dihydroorotate dehydrogenase,
mitochondrial precursor; n=4; Saccharomycetales|Rep:
Dihydroorotate dehydrogenase, mitochondrial precursor -
Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 444
Score = 143 bits (347), Expect = 3e-33
Identities = 78/181 (43%), Positives = 112/181 (61%), Gaps = 18/181 (9%)
Frame = +3
Query: 165 NSYYENVLQPLSQYLSPEV--AHRIGVAAIKHGLFPPDQ-NEDPKILKTRLLDYDLSNPL 335
++ +E V PL + ++P+ H++G+ +K+GL P ++D +LK + +SNP+
Sbjct: 61 SAIHEYVSCPLVRLVTPDAEDGHKLGIWFLKYGLAPKLMFDKDDPVLKVEVFGKTMSNPI 120
Query: 336 GIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSI 515
G AAG DK G+A+ G+ + GF +E+G+VTP QPGNPKPR FRLP D AVINRYGFNS
Sbjct: 121 GCAAGLDKDGEAIDGIAQSGFGYVEIGTVTPLAQPGNPKPRFFRLPMDEAVINRYGFNSS 180
Query: 516 GHDEVYKK-LEGIEK--------------AVMNRALLGVNLGKNKLSDDAGKDYVSGIEK 650
GH +VY L + + A+ LLG+NLGKNK D+ +DY+ G+EK
Sbjct: 181 GHKKVYDNVLSRVRQFLGAYFRDDTVNSLALYKDKLLGINLGKNKNGDEV-EDYLRGVEK 239
Query: 651 F 653
F
Sbjct: 240 F 240
>UniRef50_Q4FP58 Cluster: Dihydroorotate dehydrogenase; n=3;
Bacteria|Rep: Dihydroorotate dehydrogenase -
Pelagibacter ubique
Length = 350
Score = 140 bits (339), Expect = 3e-32
Identities = 67/151 (44%), Positives = 98/151 (64%), Gaps = 2/151 (1%)
Frame = +3
Query: 207 LSPEVAHRIGVAAIKHGLFP--PDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVG 380
+ PE AH + + ++K + P DQN+ I KT L ++ NP+G+AAGFDK+ +
Sbjct: 12 IDPETAHNLAIKSLKLNILPNIADQNKGDPIFKTNLFGKNIDNPIGMAAGFDKNAEVYNP 71
Query: 381 LMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKA 560
L KLGF +EVG+VTP Q GNPKPRVFRL ED A+INR GFN++G + + ++ ++
Sbjct: 72 LFKLGFGFVEVGTVTPLEQYGNPKPRVFRLVEDQALINRLGFNNLGAENISHRI----RS 127
Query: 561 VMNRALLGVNLGKNKLSDDAGKDYVSGIEKF 653
++ LLG+N+G NK S+D DY+ G+ F
Sbjct: 128 NSHKGLLGINIGPNKDSEDRLNDYLIGLRNF 158
>UniRef50_O01815 Cluster: Putative uncharacterized protein W02D3.2;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein W02D3.2 - Caenorhabditis elegans
Length = 411
Score = 140 bits (338), Expect = 4e-32
Identities = 77/169 (45%), Positives = 106/169 (62%), Gaps = 7/169 (4%)
Frame = +3
Query: 168 SYYENVLQPL-SQYLSPEVAHRIGVAAIKHGLFPP---DQNEDPKILKTRLLDYDLSNPL 335
++Y+ + P+ +++ E +HR V A GL P ++ E P+ LK L + NP+
Sbjct: 45 TFYKKAVMPMVHKFVDGEDSHRWAVRAASWGLLPRFGWNRKEYPE-LKCELFGREFKNPI 103
Query: 336 GIAAGFDKHGDAVVGLMK-LGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNS 512
G+AAGFDK G A+ L K GF +IE+GSVTP PQPGN +PRVFRL ED VINRYGFNS
Sbjct: 104 GLAAGFDKDGQAITQLAKNSGFGLIEIGSVTPIPQPGNNRPRVFRLLEDEGVINRYGFNS 163
Query: 513 IGHDEVYKKLEGIEKAVM--NRALLGVNLGKNKLSDDAGKDYVSGIEKF 653
G V++++ + + + A GVNLGKNKL++DA DY G+ F
Sbjct: 164 DGVGRVHQRVRSARDSWVPESYAYFGVNLGKNKLTEDAKLDYEIGVNYF 212
>UniRef50_Q0GF37 Cluster: Dihydroorotate dehydrogenase; n=2;
Ustilago maydis|Rep: Dihydroorotate dehydrogenase -
Ustilago maydis (Smut fungus)
Length = 677
Score = 140 bits (338), Expect = 4e-32
Identities = 68/156 (43%), Positives = 92/156 (58%), Gaps = 2/156 (1%)
Frame = +3
Query: 81 PLKKIRSLCYVTXXXXXXXXXXXXKKDFNSYYEN--VLQPLSQYLSPEVAHRIGVAAIKH 254
PL + + L Y+ D S + L +L PE A ++ V ++
Sbjct: 67 PLARTKQLIYLVFAIAAGTLGIAYYADSRSAIHRWIAVPALKAFLDPESAQKLAVKMLET 126
Query: 255 GLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQP 434
GL P D +D +L+T L LSNP+G+AAGFDK +A+ GL+ LGF IE+GSVTP+P
Sbjct: 127 GLAPRDLVDDDAVLETELFGRKLSNPIGLAAGFDKQAEAIDGLLDLGFGFIEIGSVTPEP 186
Query: 435 QPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
QPGNP+PR FRL ED A INR+GFNS GH+ + +L
Sbjct: 187 QPGNPQPRYFRLIEDNACINRFGFNSEGHNVILSRL 222
Score = 33.5 bits (73), Expect = 4.5
Identities = 14/26 (53%), Positives = 21/26 (80%), Gaps = 1/26 (3%)
Frame = +3
Query: 576 LLGVNLGKNKLS-DDAGKDYVSGIEK 650
+LG+NLGKNK S +++ DYV G+E+
Sbjct: 283 MLGINLGKNKTSNEESVDDYVKGVER 308
>UniRef50_P32746 Cluster: Dihydroorotate dehydrogenase,
mitochondrial precursor; n=7; Viridiplantae|Rep:
Dihydroorotate dehydrogenase, mitochondrial precursor -
Arabidopsis thaliana (Mouse-ear cress)
Length = 460
Score = 139 bits (337), Expect = 5e-32
Identities = 78/175 (44%), Positives = 100/175 (57%), Gaps = 21/175 (12%)
Frame = +3
Query: 183 VLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKH 362
V+ P L E AH++ V+A G P ++ DP IL + SNP+G+AAGFDK+
Sbjct: 87 VVNPFFALLDAEFAHKLAVSAAARGWVPREKRPDPAILGLEVWGRKFSNPIGLAAGFDKN 146
Query: 363 GDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
+A GL+ +GF +EVGSVTP PQ GNPKPR+FRL ++GA+INR GFNS G V K+L
Sbjct: 147 AEATEGLLGMGFGFVEVGSVTPVPQEGNPKPRIFRLSQEGAIINRCGFNSEGIVVVAKRL 206
Query: 543 ---EGIEKAVMNRA------------------LLGVNLGKNKLSDDAGKDYVSGI 644
G A +LGVNLGKNK S+DA DYV G+
Sbjct: 207 GAQHGKRMLAETSATSSSPSDDVKPGGKSGPGILGVNLGKNKTSEDAAADYVQGV 261
>UniRef50_Q1GGD3 Cluster: Dihydroorotate dehydrogenase; n=24;
Alphaproteobacteria|Rep: Dihydroorotate dehydrogenase -
Silicibacter sp. (strain TM1040)
Length = 352
Score = 136 bits (330), Expect = 3e-31
Identities = 70/153 (45%), Positives = 98/153 (64%), Gaps = 1/153 (0%)
Frame = +3
Query: 177 ENVLQPLSQYLSPEVAHRIGVAAIKHGLFP-PDQNEDPKILKTRLLDYDLSNPLGIAAGF 353
E + L L PE AH + + A++ GL P P P+ L+T + L NP+G+AAGF
Sbjct: 5 EKLALGLMHRLDPETAHGLSIKALRAGLTPRPGPVTSPR-LRTDVAGLSLPNPVGLAAGF 63
Query: 354 DKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVY 533
DK+ +A+ L + GF IEVG+ TP+PQPGNPKPR+FRL ED A INR+GFN+ G D +
Sbjct: 64 DKNAEALAPLSEAGFGFIEVGAATPRPQPGNPKPRLFRLSEDRAAINRFGFNNEGMDTIG 123
Query: 534 KKLEGIEKAVMNRALLGVNLGKNKLSDDAGKDY 632
K+L K+ ++G+NLG NK S+D +D+
Sbjct: 124 KRLAQRPKS----GVIGLNLGANKDSEDRAQDF 152
>UniRef50_A7AUQ8 Cluster: Dihydroorotate dehydrogenase; n=1; Babesia
bovis|Rep: Dihydroorotate dehydrogenase - Babesia bovis
Length = 415
Score = 136 bits (329), Expect = 4e-31
Identities = 67/159 (42%), Positives = 103/159 (64%), Gaps = 6/159 (3%)
Frame = +3
Query: 156 KDFNSYYENVLQPLSQ-YLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNP 332
+D NS NVL PL + YL PEVAH++ + A+K G+ P D + DP ++++RL D NP
Sbjct: 15 RDPNSVLYNVLMPLFRNYLDPEVAHKLSITALKLGIAPVDYSVDPPVIQSRLKDVVFFNP 74
Query: 333 LGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNS 512
+G+AAG+DK + + ++++GF +EVG+V P PQ GNPKP +FRL + A+IN GFNS
Sbjct: 75 IGMAAGYDKQVEVPLQILRMGFGFVEVGTVLPLPQEGNPKPVMFRLHDSKALINCCGFNS 134
Query: 513 IGHDEVYKKLEGIEKAVMNRAL-----LGVNLGKNKLSD 614
+G + +L+ + K + L +GV++GKN+ D
Sbjct: 135 VGLEVAKARLKRVRKKQASDPLTKDFMIGVSVGKNRTGD 173
>UniRef50_Q2GEM2 Cluster: Dihydroorotate dehydrogenase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Dihydroorotate
dehydrogenase - Neorickettsia sennetsu (strain Miyayama)
Length = 348
Score = 135 bits (327), Expect = 8e-31
Identities = 72/157 (45%), Positives = 102/157 (64%), Gaps = 4/157 (2%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIKH--GLFPPDQNEDPKILKTRLLDYDLSNPLGIAA 347
+E +L L Q L+P AH + +KH G + EDP IL++R+ NP+GIAA
Sbjct: 2 HEKLLVALLQRLNPSFAHDVTRVVLKHFPGFVSQNSFEDP-ILESRVCGLHFKNPIGIAA 60
Query: 348 GFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDE 527
GFDK+ + V L ++GF IE+G+VT +PQ GNP PR+FRLP+DGA+INR GFN+ G
Sbjct: 61 GFDKNAECVTALRRVGFGFIELGTVTLKPQKGNPSPRLFRLPQDGAIINRLGFNNKG--- 117
Query: 528 VYKKLEGIEKAVMNRAL--LGVNLGKNKLSDDAGKDY 632
+ L+ ++KA+ + L LGVN+GKN +S +A DY
Sbjct: 118 IAYFLKSLKKAMTHMDLPPLGVNIGKNAVSSNAVSDY 154
>UniRef50_Q5KK62 Cluster: Dihydroorotate dehydrogenase,
mitochondrial, putative; n=2; Filobasidiella
neoformans|Rep: Dihydroorotate dehydrogenase,
mitochondrial, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 591
Score = 134 bits (325), Expect = 1e-30
Identities = 80/187 (42%), Positives = 103/187 (55%), Gaps = 30/187 (16%)
Frame = +3
Query: 174 YENVLQPLSQYLS-PEVAHRIGVAAIKHGLF--PPDQNEDPKILKTRLLDYDLSNPLGIA 344
+E+V PL + ++ PE H++ V + + P D D L+ L L NP+GIA
Sbjct: 61 HEHVAMPLMRLVADPEQGHKLAVRVLAWDKWARPRDMGVDGAELQAELFGMHLKNPVGIA 120
Query: 345 AGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHD 524
AGFDK +A+ GL LGF +EVGSVTP+PQPGNPKPR FRL ED A INRYGFNS+GH
Sbjct: 121 AGFDKDAEAIDGLFDLGFGYVEVGSVTPEPQPGNPKPRFFRLEEDDACINRYGFNSLGHG 180
Query: 525 EVYKKLE--------------------------GIEKAVMNRALLGVNLGKNKLSD-DAG 623
+L G+ +++ LL VNLGKNK SD D+
Sbjct: 181 HALARLRLRLAKFAQDHPSLFPSPLPANLVPPAGLPRSLRAGQLLAVNLGKNKASDPDSN 240
Query: 624 KDYVSGI 644
DYV G+
Sbjct: 241 DDYVRGV 247
>UniRef50_Q8G2K8 Cluster: Dihydroorotate dehydrogenase; n=29;
cellular organisms|Rep: Dihydroorotate dehydrogenase -
Brucella suis
Length = 364
Score = 133 bits (322), Expect = 3e-30
Identities = 64/146 (43%), Positives = 93/146 (63%)
Frame = +3
Query: 216 EVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLG 395
E AH + + +K G+ EDP L ++ NPLG+AAG+DK+ + L+KLG
Sbjct: 19 EQAHGLSITGLKTGIVTCRTPEDPA-LSVKVAGLKFPNPLGMAAGYDKNAEVPDALLKLG 77
Query: 396 FSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRA 575
F EVG++TP+PQ GNP+PR+FRL +D AVINR GFN+ GH+ +K+L +
Sbjct: 78 FGFAEVGTLTPRPQSGNPRPRIFRLVDDKAVINRLGFNNEGHEAAFKRL---SRRAGKSG 134
Query: 576 LLGVNLGKNKLSDDAGKDYVSGIEKF 653
++GVN+G NK ++D DYV+GI +F
Sbjct: 135 IVGVNIGANKDAEDRIADYVAGIRRF 160
>UniRef50_P28294 Cluster: Dihydroorotate dehydrogenase; n=8;
cellular organisms|Rep: Dihydroorotate dehydrogenase -
Agrocybe aegerita (Black poplar mushroom)
Length = 328
Score = 133 bits (322), Expect = 3e-30
Identities = 64/146 (43%), Positives = 92/146 (63%)
Frame = +3
Query: 216 EVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLG 395
E AH + +A +K GL D L ++ NPLG+AAG+DK+ + L+KLG
Sbjct: 19 EQAHGLSIAGLKTGLVTGSAPND-LALSVKVAGLQFPNPLGMAAGYDKNAEVPDALLKLG 77
Query: 396 FSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRA 575
F E+G++TP+PQ GNP+PR+FRL +D AVINR GFN+ GHD +K+L +
Sbjct: 78 FGFTEIGTITPRPQSGNPRPRIFRLVDDKAVINRLGFNNEGHDAAFKRL---SQRAGKSG 134
Query: 576 LLGVNLGKNKLSDDAGKDYVSGIEKF 653
++GVN+G NK ++D DYV+GI +F
Sbjct: 135 IVGVNIGANKDAEDRIADYVAGIRRF 160
>UniRef50_Q4UDM3 Cluster: Dihydroorotate dehydrogenase,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydroorotate dehydrogenase, mitochondrial, putative -
Theileria annulata
Length = 377
Score = 128 bits (309), Expect = 1e-28
Identities = 58/148 (39%), Positives = 95/148 (64%), Gaps = 5/148 (3%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGF 353
Y+ +L L +++ PE +H++ + K GL P D + DP IL + + NP+G+AAG+
Sbjct: 17 YDGILYGLRKWVDPEDSHKLSIFLAKLGLTPVDYSIDPPILYNNIKHIKIFNPIGMAAGY 76
Query: 354 DKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVY 533
DK+ + + +++LGF IE+G+V P+PQPGNPKPR+FRLP + A+IN GFNS+G D
Sbjct: 77 DKNCEVALEILRLGFGFIELGTVLPKPQPGNPKPRLFRLPNNKALINCLGFNSLGIDTAV 136
Query: 534 KKLEGIEKAVMN-----RALLGVNLGKN 602
+ ++ N +++G+++GKN
Sbjct: 137 ENMKATRARQKNDPLTKDSIIGISIGKN 164
>UniRef50_Q5FTP3 Cluster: Dihydroorotate dehydrogenase; n=3;
Acetobacteraceae|Rep: Dihydroorotate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 357
Score = 126 bits (304), Expect = 5e-28
Identities = 68/156 (43%), Positives = 90/156 (57%), Gaps = 6/156 (3%)
Frame = +3
Query: 183 VLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKH 362
++ PL E AH + + ++ GL + P L TR L NP+G+AAGFDK
Sbjct: 7 LVTPLLHRFDTETAHELAIHSLALGLGGHAPKDVPA-LSTRTLGLRFPNPIGLAAGFDKD 65
Query: 363 GDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
A+ L KLGF IE G+VTP+PQPGNP PR+FRL EDGA+INR GFN G D ++L
Sbjct: 66 ARAIRPLAKLGFGHIEAGTVTPRPQPGNPGPRLFRLVEDGAIINRMGFNGCGVDRFCRRL 125
Query: 543 EGIEKAVMNRAL------LGVNLGKNKLSDDAGKDY 632
+ + + N + LGVN+G NK D +DY
Sbjct: 126 ARLHRPMPNGRMRGPTVPLGVNIGINKTGSDPLRDY 161
>UniRef50_Q7RLG4 Cluster: Dihydroorotate dehydrogenase, putative;
n=4; Plasmodium (Vinckeia)|Rep: Dihydroorotate
dehydrogenase, putative - Plasmodium yoelii yoelii
Length = 512
Score = 124 bits (298), Expect = 2e-27
Identities = 62/164 (37%), Positives = 100/164 (60%), Gaps = 5/164 (3%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGF 353
Y+ L +Y+ EV H + + K+GL P D + D + + + + NP G+AAGF
Sbjct: 137 YDVFLDLCLKYVDSEVCHDLFLLLGKYGLLPYDTSNDSVYATSDIKNLNFINPFGVAAGF 196
Query: 354 DKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVY 533
DK+G + ++KLGFS IE+G++TP+PQ GN KPR+FR E+ ++IN GFN+IG D+V
Sbjct: 197 DKNGICIDSILKLGFSFIEIGTITPKPQKGNDKPRIFRDVENKSIINACGFNNIGCDKVT 256
Query: 534 KKLEGIEK-----AVMNRALLGVNLGKNKLSDDAGKDYVSGIEK 650
+ L K ++++ ++GV++GKNK +++ D I K
Sbjct: 257 ENLISFRKKQEEDKLLSKHIVGVSIGKNKYTENIVDDLKYSIYK 300
>UniRef50_Q6G4F7 Cluster: Dihydroorotate dehydrogenase; n=3;
Rhizobiales|Rep: Dihydroorotate dehydrogenase -
Bartonella henselae (Rochalimaea henselae)
Length = 362
Score = 122 bits (293), Expect = 1e-26
Identities = 62/149 (41%), Positives = 91/149 (61%)
Frame = +3
Query: 207 LSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLM 386
L PE AHR+ + +K GL + D ++ T + N +G+AAGFDK+ + V +
Sbjct: 15 LDPEHAHRLAIMGLKSGLNSYQKVVDNRLCVT-IAGLKFENFIGLAAGFDKNAEVVNDVF 73
Query: 387 KLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVM 566
LGF E+G+VTP+PQ GNPKPR+FRL +D A+INR GFN+ G VY +L G ++
Sbjct: 74 HLGFGFTEIGTVTPRPQVGNPKPRLFRLRKDEAIINRMGFNNDGRQIVYGRLHGYKRL-- 131
Query: 567 NRALLGVNLGKNKLSDDAGKDYVSGIEKF 653
++G+N+G NK + D DY++ I F
Sbjct: 132 --GIVGINIGANKDTVDKIDDYITSIAYF 158
>UniRef50_A5K1N1 Cluster: Dihydroorotate dehydrogenase,
mitochondrial, putative; n=1; Plasmodium vivax|Rep:
Dihydroorotate dehydrogenase, mitochondrial, putative -
Plasmodium vivax
Length = 572
Score = 121 bits (291), Expect = 2e-26
Identities = 63/157 (40%), Positives = 96/157 (61%), Gaps = 5/157 (3%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGF 353
Y+ L+ L +Y+ E H + + K+ L P D +D + + + NP G+AAGF
Sbjct: 170 YDVFLKMLLKYVDGETCHELFLLMGKYKLLPYDTGKDNIYSCSEIKGLNFINPFGVAAGF 229
Query: 354 DKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVY 533
DK+G + G++KLGFS IE+G++TP+ Q GN +PR+FR E ++IN GFN++G DEV
Sbjct: 230 DKNGVCIDGILKLGFSFIEIGTITPKAQKGNERPRIFRDLETRSIINSCGFNNMGCDEVC 289
Query: 534 KKLEGIEK-----AVMNRALLGVNLGKNKLSDDAGKD 629
K L+ + ++ R L+GV+LGKNK S D +D
Sbjct: 290 KNLKRFRERQKTDKLLQRHLVGVSLGKNKDSPDILQD 326
>UniRef50_Q5PBF6 Cluster: Dihydroorotate dehydrogenase; n=12;
Rickettsiales|Rep: Dihydroorotate dehydrogenase -
Anaplasma marginale (strain St. Maries)
Length = 389
Score = 120 bits (290), Expect = 2e-26
Identities = 56/143 (39%), Positives = 86/143 (60%)
Frame = +3
Query: 204 YLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGL 383
++ PEVAH + + +KHGLFP + + P+ L + P+G+AAGFDK+ + + L
Sbjct: 49 WVPPEVAHGLVIFGLKHGLFPEVRGQMPECLSIEVCHLRFRTPIGLAAGFDKNAEVIKPL 108
Query: 384 MKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAV 563
+ +GF +E G+VT +PQ GN +PR+FR+ + AV+NR GFN+ G KK I++
Sbjct: 109 IGMGFGFVEAGTVTKKPQSGNKRPRLFRIVDQKAVVNRLGFNNKGIQRFIKK---IDRKE 165
Query: 564 MNRALLGVNLGKNKLSDDAGKDY 632
+N + G NLG NK D +Y
Sbjct: 166 LNNLVFGANLGINKTCTDPPAEY 188
>UniRef50_A2VBP6 Cluster: Dihydroorotate dehydrogenase,
mitochondrial; n=1; Dekkera bruxellensis|Rep:
Dihydroorotate dehydrogenase, mitochondrial - Dekkera
bruxellensis (Brettanomyces custersii)
Length = 442
Score = 120 bits (290), Expect = 2e-26
Identities = 73/175 (41%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Frame = +3
Query: 177 ENVLQPLSQYLSP-EVAHRIGVAAIKHGLFPP--DQNEDPKILKTRLLDYDLSNPLGIAA 347
E V PL ++ + E H +G+A +K+G+FP ++DP IL+ L L+NP+G+AA
Sbjct: 68 EYVWCPLFRWCTTAEQGHHLGIALLKYGIFPRAFGDHDDP-ILRVDLFGRTLANPIGMAA 126
Query: 348 GFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDE 527
GFDK +A+ L LGF I+EVG++TP+PQ GNP+PR FRL D VINRYG NS G
Sbjct: 127 GFDKQAEAMDALYDLGFGIVEVGTITPEPQFGNPRPRFFRLNADETVINRYGLNSDGRLT 186
Query: 528 VYKKLE-GIEKAV-------MNRAL-----LGVNLGKNKLSDDAGKDYVSGIEKF 653
+ +L +EK + N + L VN+GKN+ + D DY+ G++ F
Sbjct: 187 ILSRLRVRLEKYLKKSNACKTNNSFREGKSLFVNIGKNR-NGDTIDDYLVGVDTF 240
>UniRef50_Q83GM4 Cluster: Dihydroorotate oxidase; n=2; Tropheryma
whipplei|Rep: Dihydroorotate oxidase - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 335
Score = 116 bits (280), Expect = 4e-25
Identities = 67/164 (40%), Positives = 95/164 (57%), Gaps = 4/164 (2%)
Frame = +3
Query: 168 SYYENVLQPLSQYLSPEVAHRIGVAAIKHGL--FPPDQNEDPKILKTRLLDYDLSNPLGI 341
SY+ N L+ + PE+AHRI A+K GL F P + L T + PLGI
Sbjct: 3 SYFLNFLK----CVDPELAHRIAAVALKSGLGMFVPQRFHIH--LGTTSMGLYFDTPLGI 56
Query: 342 AAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGH 521
AAGFDK D V+ L LGF +EVG+VT PQPGN KPR+ R+ A+IN GFN+ G
Sbjct: 57 AAGFDKFADLVIPLYSLGFGHVEVGTVTLHPQPGNKKPRIHRVMSQKALINSMGFNNPGA 116
Query: 522 DEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYVSGIE 647
++ + + + K+ ++GVN+GK+K+ +++ KDYV E
Sbjct: 117 QKMRENILKVRKSGRRLPIIGVNIGKSKVCPLEESAKDYVKSFE 160
>UniRef50_Q0RAG2 Cluster: Dihydroorotate dehydrogenase; n=1;
Wolbachia endosymbiont of Onchocerca volvulus|Rep:
Dihydroorotate dehydrogenase - Onchocerca volvulus
endobacterium
Length = 365
Score = 116 bits (279), Expect = 5e-25
Identities = 58/154 (37%), Positives = 87/154 (56%)
Frame = +3
Query: 186 LQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHG 365
L L L PE+AH + + +K + P+ L D L +P+G+AAGFDK+
Sbjct: 21 LHNLLLLLPPEIAHSLVIMILKKIPYKKPIEHLPESLNVNFFDNKLKSPIGLAAGFDKNA 80
Query: 366 DAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLE 545
+ + ++ GF IE G+VT PQ GN KPR+FRL +D +INR GFN+ G + L+
Sbjct: 81 EVISSMLSFGFGFIEAGTVTKYPQYGNKKPRIFRLTQDEGIINRLGFNNKG---IGYFLK 137
Query: 546 GIEKAVMNRALLGVNLGKNKLSDDAGKDYVSGIE 647
I K +N + G+N+GKN +S + DY+ I+
Sbjct: 138 QINKIRLNNDIFGINIGKNSISQNKISDYIDLIK 171
>UniRef50_A5EV79 Cluster: Dihydroorotate dehydrogenase; n=1;
Dichelobacter nodosus VCS1703A|Rep: Dihydroorotate
dehydrogenase - Dichelobacter nodosus (strain VCS1703A)
Length = 337
Score = 116 bits (279), Expect = 5e-25
Identities = 65/153 (42%), Positives = 94/153 (61%), Gaps = 3/153 (1%)
Frame = +3
Query: 186 LQPLSQYLSPEVAHRIGVAAIKHG-LFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKH 362
L+PL L+PE+AH + + + +F P I LL + N LG+AAG DK+
Sbjct: 7 LRPLLFCLNPEIAHNLTLQILSRAAVFIPRIKAGNPI---HLLGHTFPNRLGLAAGLDKN 63
Query: 363 GDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
A+ +LGF IEVG+ TP+PQ GNPKPR+FRLPE A+IN GFN+ G + +++
Sbjct: 64 AVAISAFDRLGFGFIEVGTATPRPQSGNPKPRLFRLPEHQAIINCMGFNNDGVVALCQQV 123
Query: 543 EGIEKAVMNRALLGVNLGKNKL--SDDAGKDYV 635
++K RAL+G+N+GKNKL ++ A DY+
Sbjct: 124 AAVKK--RTRALIGINIGKNKLTPNERAADDYL 154
>UniRef50_Q9PAE7 Cluster: Dihydroorotate dehydrogenase; n=155;
Bacteria|Rep: Dihydroorotate dehydrogenase - Xylella
fastidiosa
Length = 351
Score = 116 bits (279), Expect = 5e-25
Identities = 64/162 (39%), Positives = 91/162 (56%), Gaps = 5/162 (3%)
Frame = +3
Query: 180 NVLQPLSQYLSPEVAHRIGVAAIK---HGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAG 350
++ +PL E AH I + + H P P+ L T + NP+G+AAG
Sbjct: 3 SLFRPLLFTCDTERAHDISLCTLDIAYHSGALPLLTRHPRPLPTTAFGLNFPNPVGLAAG 62
Query: 351 FDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEV 530
DK+G + L LGF IE+G+ TP+PQPGNPKPR+FRL + AVINR GFN++G D +
Sbjct: 63 LDKNGTHIDALFALGFGFIEIGTTTPRPQPGNPKPRLFRLTQQQAVINRMGFNNLGVDAL 122
Query: 531 YKKLEGIEKAVMNRALLGVNLGKNK--LSDDAGKDYVSGIEK 650
+ + G A LG+N+GKNK ++ A DY +E+
Sbjct: 123 VRNVAG---ARQRNGPLGINIGKNKDTPNEQASNDYRYCLER 161
>UniRef50_Q0LH17 Cluster: Dihydroorotate dehydrogenase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Dihydroorotate
dehydrogenase - Herpetosiphon aurantiacus ATCC 23779
Length = 356
Score = 115 bits (277), Expect = 9e-25
Identities = 66/156 (42%), Positives = 93/156 (59%), Gaps = 10/156 (6%)
Frame = +3
Query: 207 LSPEVAHRIGVAAIK--------HGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKH 362
L PE AHR+ + LF + DP +LKT L +NP+G+AAGFDK
Sbjct: 14 LPPEKAHRLTTLGLDLATRLPFTSALFRSFHHNDP-LLKTNLCGLTFNNPVGLAAGFDKD 72
Query: 363 GDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
G + G+ +LGF +E+G+VTP+PQ GN +PR+FRL ED A+INR GFN+ G + ++L
Sbjct: 73 GTHIRGMSQLGFGFLELGTVTPKPQAGNEQPRLFRLIEDHALINRMGFNNAGIAALAQRL 132
Query: 543 EGIEKAVMNRALLGVNLGKNKL--SDDAGKDYVSGI 644
+ + LG+NLGKNK+ ++ A DY GI
Sbjct: 133 AKQPRIIP----LGINLGKNKITPNEQAADDYRQGI 164
>UniRef50_A5AEM5 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 310
Score = 114 bits (275), Expect = 2e-24
Identities = 52/103 (50%), Positives = 69/103 (66%)
Frame = +3
Query: 183 VLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKH 362
++ P L EVAHR+ V+A GL P ++ DP IL + SNP+G+AAGFDK+
Sbjct: 87 LVNPFFALLDAEVAHRLAVSAAARGLVPREKRPDPSILGLEVWGRKFSNPVGLAAGFDKN 146
Query: 363 GDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVI 491
+AV GL+ LGF +EVGSVTP PQ GNPKPR+FRL +G ++
Sbjct: 147 AEAVEGLLGLGFGFVEVGSVTPVPQEGNPKPRIFRLRHEGDIV 189
Score = 39.5 bits (88), Expect = 0.069
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +3
Query: 576 LLGVNLGKNKLSDDAGKDYVSGI 644
+LGVNLGKNK S+DA DYV G+
Sbjct: 277 ILGVNLGKNKTSEDAAADYVQGV 299
>UniRef50_Q08210 Cluster: Dihydroorotate dehydrogenase homolog,
mitochondrial precursor; n=3; Plasmodium falciparum|Rep:
Dihydroorotate dehydrogenase homolog, mitochondrial
precursor - Plasmodium falciparum (isolate 3D7)
Length = 569
Score = 114 bits (275), Expect = 2e-24
Identities = 63/186 (33%), Positives = 104/186 (55%), Gaps = 5/186 (2%)
Frame = +3
Query: 63 MSQKKDPLKKIRSLCYVTXXXXXXXXXXXXKKDFNSYYENVLQPLSQYLSPEVAHRIGVA 242
+ ++K KKI L +V+ + F Y+ L+ +Y+ E+ H + +
Sbjct: 133 IKKEKSKHKKIIFLLFVSLFGLYGFFESYNPEFF--LYDIFLKFCLKYIDGEICHDLFLL 190
Query: 243 AIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSV 422
K+ + P D + D T + D NP G+AAGFDK+G + ++KLGFS IE+G++
Sbjct: 191 LGKYNILPYDTSNDSIYACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTI 250
Query: 423 TPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL-----EGIEKAVMNRALLGV 587
TP+ Q GN KPR+FR E ++IN GFN++G D+V + L E ++++ ++GV
Sbjct: 251 TPRGQTGNAKPRIFRDVESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKHIVGV 310
Query: 588 NLGKNK 605
++GKNK
Sbjct: 311 SIGKNK 316
>UniRef50_A5UX75 Cluster: Dihydroorotate oxidase; n=1; Roseiflexus
sp. RS-1|Rep: Dihydroorotate oxidase - Roseiflexus sp.
RS-1
Length = 361
Score = 114 bits (274), Expect = 2e-24
Identities = 62/122 (50%), Positives = 80/122 (65%), Gaps = 2/122 (1%)
Frame = +3
Query: 279 EDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPR 458
EDP +L +NP+G+AAGFDK D V GL LGF IEVG+VTP+PQPGNP+PR
Sbjct: 48 EDP-LLAVDWSGLHFANPVGVAAGFDKRADLVDGLALLGFGHIEVGTVTPRPQPGNPRPR 106
Query: 459 VFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDY 632
+FRLPED A+INR GFNS G V + L ++GVN+GKN+ + + A +DY
Sbjct: 107 LFRLPEDTALINRLGFNSPGMVAVARALRARRS---RDVIVGVNIGKNRDTPLERAVEDY 163
Query: 633 VS 638
V+
Sbjct: 164 VA 165
>UniRef50_Q6AE78 Cluster: Dihydroorotate dehydrogenase; n=6;
Actinomycetales|Rep: Dihydroorotate dehydrogenase -
Leifsonia xyli subsp. xyli
Length = 343
Score = 110 bits (265), Expect = 2e-23
Identities = 67/163 (41%), Positives = 89/163 (54%), Gaps = 9/163 (5%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIKH-------GLFPPDQNEDPKILKTRLLDYDLSNP 332
Y + + PE AHR+ AAI+ L DP L L +P
Sbjct: 2 YRTLFSLVLSRFDPERAHRLAFAAIRALPVIGLGSLLRRFTAPDPS-LAVEALGLRFDSP 60
Query: 333 LGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNS 512
GIAAGFDK G+ V+GL LGF +EVG++T +PQPGN KPR+FRL D AVINR GFN+
Sbjct: 61 FGIAAGFDKDGEGVIGLGALGFGHVEVGTITARPQPGNDKPRLFRLLPDRAVINRMGFNN 120
Query: 513 IGHDEVYKKLEGIEKAVMNRALLGVNLGKNK--LSDDAGKDYV 635
G +L + +A R +LGVN+ K++ +DA DY+
Sbjct: 121 HGAGAAANRLLRVRRA-RRRPVLGVNISKSRAVAVEDATADYL 162
>UniRef50_Q62K45 Cluster: Dihydroorotate dehydrogenase; n=38;
cellular organisms|Rep: Dihydroorotate dehydrogenase -
Burkholderia mallei (Pseudomonas mallei)
Length = 345
Score = 110 bits (265), Expect = 2e-23
Identities = 55/110 (50%), Positives = 75/110 (68%), Gaps = 2/110 (1%)
Frame = +3
Query: 327 NPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGF 506
NP+G+AAG DK G A+ G LGF IEVG+VTP+ QPGNP+PR+FRLPE A+INR GF
Sbjct: 59 NPVGLAAGLDKDGAAIDGFAALGFGFIEVGTVTPRAQPGNPRPRMFRLPEADAIINRMGF 118
Query: 507 NSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYVSGIEK 650
N+ G D+ K ++ A R +LG+N+GKN + + A DY+ +E+
Sbjct: 119 NNSGVDQFVKNVQ----AARYRGVLGLNIGKNADTPIERAADDYLYCLER 164
>UniRef50_A7CXZ7 Cluster: Dihydroorotate oxidase; n=1; Opitutaceae
bacterium TAV2|Rep: Dihydroorotate oxidase - Opitutaceae
bacterium TAV2
Length = 377
Score = 109 bits (263), Expect = 4e-23
Identities = 64/166 (38%), Positives = 93/166 (56%), Gaps = 11/166 (6%)
Frame = +3
Query: 171 YYENVLQPLSQYLSPEVAHRIGVAAIKH-GLFPP------DQNEDPKIL--KTRLLDYDL 323
+YE + +P+ L E AH + V + G PP N P+ + R+ +
Sbjct: 30 FYEKIARPMFFRLDCEPAHELAVMGMSLLGKLPPLCRALEAWNRVPRSVFCPVRVFGLEF 89
Query: 324 SNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYG 503
N +G+AAGFDK G A +GF E+G+VT QPGNPKPR+FR P AVINR G
Sbjct: 90 PNAVGLAAGFDKGGTAWPAAAAMGFGHAEIGTVTALAQPGNPKPRMFRYPAQEAVINRMG 149
Query: 504 FNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYV 635
FN+ G + + K+L + A R +LG+NLGK+K++ ++A DY+
Sbjct: 150 FNNDGAENLAKRLARLAPAGRRRVVLGINLGKSKVASLEEAVGDYL 195
>UniRef50_Q8EYC6 Cluster: Dihydroorotate dehydrogenase; n=4;
Leptospira|Rep: Dihydroorotate dehydrogenase -
Leptospira interrogans
Length = 382
Score = 108 bits (259), Expect = 1e-22
Identities = 65/171 (38%), Positives = 91/171 (53%), Gaps = 10/171 (5%)
Frame = +3
Query: 168 SYYENVLQPLSQYLSPEVAHRIGVAAIKHG--------LFPPDQNEDPKILKTRLLDYDL 323
S Y L+P L PE AH + + G L + LKT++ +
Sbjct: 19 SAYSVFLKPFFLSLDPETAHELAKNFLGIGQKFPGFLTLMESMTSYQSDRLKTKIAGIEF 78
Query: 324 SNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYG 503
NPLG+ AGFDK G+ L ++GF IEVG++T Q Q GNPKPRVFR P+D A++NR G
Sbjct: 79 ENPLGMGAGFDKTGELYPFLSRMGFGHIEVGTITGQKQSGNPKPRVFRYPQDQALVNRMG 138
Query: 504 FNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKL--SDDAGKDYVSGIEK 650
FN+ G D K + +K + G+N GK K+ + A +DYV ++K
Sbjct: 139 FNNPGADSAEKIISSQKKT----KIRGINAGKTKIVPEEKAVEDYVYTLKK 185
>UniRef50_A2QCB1 Cluster: Catalytic activity:; n=9;
Pezizomycotina|Rep: Catalytic activity: - Aspergillus
niger
Length = 544
Score = 107 bits (256), Expect = 3e-22
Identities = 59/126 (46%), Positives = 75/126 (59%), Gaps = 8/126 (6%)
Frame = +3
Query: 192 PLSQYLSPEV--AHRIGVAAIK----HGLFPPDQNEDPK--ILKTRLLDYDLSNPLGIAA 347
PL + L P+ AH GV +K +GL P ++ + L T + Y LSNP+GI+
Sbjct: 129 PLVRLLFPDAEDAHHFGVDILKTLYKYGLNPRERGDPDSDGALLTEVFGYTLSNPIGISG 188
Query: 348 GFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDE 527
G DKH D L +LG +I+EVG TP PQ GNP+PRVFRLP A+INRYG NS G D
Sbjct: 189 GLDKHADIPDPLFELGPAIVEVGGTTPLPQDGNPRPRVFRLPSQKAMINRYGLNSKGADH 248
Query: 528 VYKKLE 545
+ LE
Sbjct: 249 MAAVLE 254
>UniRef50_Q2YWG7 Cluster: Dihydroorotate dehydrogenase; n=16;
Staphylococcus|Rep: Dihydroorotate dehydrogenase -
Staphylococcus aureus (strain bovine RF122)
Length = 354
Score = 103 bits (247), Expect = 4e-21
Identities = 63/168 (37%), Positives = 98/168 (58%), Gaps = 11/168 (6%)
Frame = +3
Query: 183 VLQPLSQYLSPEVAHRIGVAAIKH-----GLFPPDQN----EDPKILKTRLLDYDLSNPL 335
+++P + PE AH + + A+K LFP ++P + +T + NP+
Sbjct: 4 LIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTYKNPTLSQT-IQGNTYDNPI 62
Query: 336 GIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSI 515
G+AAGFDK + L LGF +E+G +TP+PQPGNP+PR+FRL ED A+INR GFN+I
Sbjct: 63 GLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQPRMFRLLEDDALINRMGFNNI 122
Query: 516 GHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYVSGIEKF 653
G + K L + K + +G+N+G NK++ + +DY+ I+ F
Sbjct: 123 G---MNKALSHLRKNAY-QVPVGINVGVNKMTPYEARYQDYIKVIDTF 166
>UniRef50_P57443 Cluster: Dihydroorotate dehydrogenase; n=3;
Proteobacteria|Rep: Dihydroorotate dehydrogenase -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 337
Score = 103 bits (246), Expect = 5e-21
Identities = 54/120 (45%), Positives = 78/120 (65%), Gaps = 2/120 (1%)
Frame = +3
Query: 297 KTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPE 476
K + + N LG AAG DK+G+ + L KLGF IEVG+VTP PQ GNPKPR+FR+
Sbjct: 47 KIKCMGLIFDNKLGTAAGIDKNGEYIDALSKLGFGFIEVGTVTPLPQVGNPKPRMFRIVS 106
Query: 477 DGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYVSGIEK 650
+INR GFN++G D + + I+K+ + ++GVN+GKNK + +++ DY+ IEK
Sbjct: 107 MEGIINRMGFNNLGIDNL---IRNIKKSNF-KGIIGVNIGKNKSTSLENSVDDYLICIEK 162
>UniRef50_A7BDH3 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 312
Score = 102 bits (245), Expect = 7e-21
Identities = 49/107 (45%), Positives = 72/107 (67%), Gaps = 3/107 (2%)
Frame = +3
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRY 500
L + LG+AAG DK +AV+G+ LG++ +E+G+VTP+PQPGN PR++RL E+ + NR
Sbjct: 32 LPSRLGLAAGMDKDAEAVLGMCALGYAFVEIGTVTPRPQPGNDAPRLWRLMEERGLRNRM 91
Query: 501 GFNSIGHDEVYKKLEGIEKAVMNRA-LLGVNLGKNKLSD--DAGKDY 632
GFN+ G D +KL + RA ++G N+GKNK++ DA DY
Sbjct: 92 GFNNAGADAAAEKLRELRSTPAGRATIVGANIGKNKVTSEADAPADY 138
>UniRef50_Q1GVC1 Cluster: Dihydroorotate dehydrogenase; n=10;
Alphaproteobacteria|Rep: Dihydroorotate dehydrogenase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 356
Score = 101 bits (242), Expect = 2e-20
Identities = 57/151 (37%), Positives = 81/151 (53%)
Frame = +3
Query: 189 QPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGD 368
+PL E AH + +AA++ P +L T L NP+G+A GFDK
Sbjct: 16 RPLVHATDGEAAHNLTLAALQPLPRARHALTSP-MLATELAGLRFPNPVGLAPGFDKDAR 74
Query: 369 AVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEG 548
+ GF +EVG++TP PQ GNP+PR+FRL ED A+INR GFN+ G +++
Sbjct: 75 VAHAMPHFGFGFVEVGTLTPLPQEGNPRPRLFRLVEDRAIINRMGFNNGGQVAAAERIAC 134
Query: 549 IEKAVMNRALLGVNLGKNKLSDDAGKDYVSG 641
+ + + LG+N+G NK S D DY G
Sbjct: 135 LRRHGL-PVPLGINIGANKDSADRIADYAKG 164
>UniRef50_Q5X496 Cluster: Dihydroorotate dehydrogenase; n=5;
Legionella pneumophila|Rep: Dihydroorotate dehydrogenase
- Legionella pneumophila (strain Paris)
Length = 333
Score = 100 bits (239), Expect = 3e-20
Identities = 50/103 (48%), Positives = 75/103 (72%), Gaps = 2/103 (1%)
Frame = +3
Query: 333 LGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNS 512
+G+AAG DK+G+ + L KLGFS IE+G+VTP+ Q GNPKPR+FR+ E A+INR GFN+
Sbjct: 52 VGLAAGLDKNGEHLDALAKLGFSFIELGTVTPKGQAGNPKPRLFRIAEANAIINRMGFNN 111
Query: 513 IGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYV 635
G D + +E +++A + +LG+N+GKNK + + A +DY+
Sbjct: 112 SGVDVL---VENVKRA-NYKGILGINIGKNKETNLNQAAEDYL 150
>UniRef50_P45477 Cluster: Dihydroorotate dehydrogenase; n=13;
Haemophilus influenzae|Rep: Dihydroorotate dehydrogenase
- Haemophilus influenzae
Length = 339
Score = 99 bits (238), Expect = 5e-20
Identities = 60/156 (38%), Positives = 89/156 (57%), Gaps = 8/156 (5%)
Frame = +3
Query: 207 LSPEVAHRIGVAAIK---HGLFPPDQNE---DPKILKTRLLDYDLSNPLGIAAGFDKHGD 368
+ E AH + +K + LF P PK ++ + NP+G+AAG DK+GD
Sbjct: 12 MDAEKAHNFTIQCLKLAGNPLFQPILKSLIHAPKGFPKTVMGVNFPNPIGLAAGADKNGD 71
Query: 369 AVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEG 548
A+ G LGF +E+G+VTP Q GN KPR FRL E +INR GFN+ G D + +E
Sbjct: 72 AIDGFGALGFGFLELGTVTPVAQDGNAKPRQFRLIEAEGIINRNGFNNNGIDYL---IEN 128
Query: 549 IEKAVMNRALLGVNLGKNKLSD-DAGK-DYVSGIEK 650
++ A + ++G+N+GKNK + + GK DY+ + K
Sbjct: 129 VKNA-RYKGVIGINIGKNKFTSLEQGKDDYIFCLNK 163
>UniRef50_A6Q8G0 Cluster: Dihydroorotate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Dihydroorotate dehydrogenase
- Sulfurovum sp. (strain NBC37-1)
Length = 354
Score = 99.5 bits (237), Expect = 6e-20
Identities = 51/119 (42%), Positives = 73/119 (61%), Gaps = 2/119 (1%)
Frame = +3
Query: 282 DPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRV 461
DP I + NP+G+ AGFDK+G + + LGF E+G+VTP+PQPGNPKPR+
Sbjct: 50 DPMI-EQEFFGRTFKNPVGLGAGFDKNGQYITSMPALGFGFTEIGTVTPKPQPGNPKPRL 108
Query: 462 FRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDD--AGKDY 632
FRL ED ++ N GFN+ G + LE + K +G+N+GKNK++ + A +DY
Sbjct: 109 FRLLEDRSIQNAMGFNNRGMGYM---LEQLNKLYFFDYPIGINIGKNKVTSEEKALEDY 164
>UniRef50_Q7U3U2 Cluster: Dihydroorotate dehydrogenase; n=25;
Cyanobacteria|Rep: Dihydroorotate dehydrogenase -
Synechococcus sp. (strain WH8102)
Length = 396
Score = 99.5 bits (237), Expect = 6e-20
Identities = 58/141 (41%), Positives = 84/141 (59%), Gaps = 4/141 (2%)
Frame = +3
Query: 237 VAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVG 416
V+ + GL Q D + L+ L NP+G+AAGFDK+G A + GF EVG
Sbjct: 51 VSTVLEGLAGDLQRRDLR-LEQVLFGCRFPNPVGLAAGFDKNGVAAGLWDRFGFGFAEVG 109
Query: 417 SVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNR--ALLGVN 590
+VT QPGNP+PR+FRL ++ A +NR GFN+ G + + LE A R A+LG+N
Sbjct: 110 TVTWHGQPGNPRPRLFRLAQEQAALNRMGFNNDGAQALRRTLERQRLAPPGRRPAVLGIN 169
Query: 591 LGKNKLS--DDAGKDYVSGIE 647
+GK+K++ + A +DY S +E
Sbjct: 170 VGKSKVTALEQAPEDYASSLE 190
>UniRef50_Q6D456 Cluster: Dihydroorotate dehydrogenase; n=4;
Enterobacteriaceae|Rep: Dihydroorotate dehydrogenase -
Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 336
Score = 99.1 bits (236), Expect = 8e-20
Identities = 60/157 (38%), Positives = 90/157 (57%), Gaps = 4/157 (2%)
Frame = +3
Query: 171 YYENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTR---LLDYDLSNPLGI 341
+Y + + L Q L PE AH + ++ P + + + T+ + NPLG+
Sbjct: 2 FYPVIKKALFQ-LDPERAHELTFQQLRRITNTPFEFLVRQSVPTKPVTCMGLSFKNPLGL 60
Query: 342 AAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGH 521
AAG DK G+ + L +GF IEVG+VTP+PQ GN KPR+FR+ E +INR GFN+ G
Sbjct: 61 AAGLDKDGECIDALGAMGFGFIEVGTVTPRPQSGNDKPRLFRVVEAEGLINRMGFNNKGV 120
Query: 522 DEVYKKLEGIEKAVMNRALLGVNLGKNKLSD-DAGKD 629
D + +E ++K +LG+N+GKNK + + GKD
Sbjct: 121 DYL---VENVKKTRFG-GVLGINIGKNKDTPVEQGKD 153
>UniRef50_Q0CXV7 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 708
Score = 97.5 bits (232), Expect = 2e-19
Identities = 50/112 (44%), Positives = 66/112 (58%)
Frame = +3
Query: 225 HRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSI 404
HR GV + L+P ++ + Y +SNP+GI+AG DKH + L LG +I
Sbjct: 97 HRYGVVPLIRLLYPDAEDAH------HIFGYTISNPIGISAGLDKHAEIPDPLFALGPAI 150
Query: 405 IEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKA 560
+EVG TP PQ GNP+PRVFRLP A+INRYG NS G D + L+ +A
Sbjct: 151 VEVGGTTPLPQEGNPRPRVFRLPSQRAMINRYGLNSKGADHMAALLDARVRA 202
>UniRef50_Q8D9G5 Cluster: Dihydroorotate dehydrogenase; n=56;
Proteobacteria|Rep: Dihydroorotate dehydrogenase -
Vibrio vulnificus
Length = 336
Score = 97.5 bits (232), Expect = 2e-19
Identities = 48/110 (43%), Positives = 74/110 (67%), Gaps = 2/110 (1%)
Frame = +3
Query: 327 NPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGF 506
NP+G+AAG DK+G+ + +GF +EVG+VTP+ Q GN KPR+FRL +INR GF
Sbjct: 56 NPVGLAAGLDKNGECIEAFDAMGFGFVEVGTVTPRAQSGNDKPRLFRLVGAEGIINRMGF 115
Query: 507 NSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYVSGIEK 650
N++G D + +E ++KA + +LG+N+GKNK + + +DY+ +EK
Sbjct: 116 NNLGVDNL---IENVKKAKYS-CVLGINIGKNKDTPIEKGAEDYLICMEK 161
>UniRef50_Q2S001 Cluster: Dihydroorotate oxidase; n=1; Salinibacter
ruber DSM 13855|Rep: Dihydroorotate oxidase -
Salinibacter ruber (strain DSM 13855)
Length = 366
Score = 97.1 bits (231), Expect = 3e-19
Identities = 66/156 (42%), Positives = 87/156 (55%), Gaps = 8/156 (5%)
Frame = +3
Query: 183 VLQPLSQYLSPEVAHRI---GVAAIKHGLFP----PDQNEDPKILKTRLLDYDLSNPLGI 341
+L+PL L+PE AH G + + P Q ED + LK RL NP+G+
Sbjct: 4 LLRPLLFRLNPEWAHTASLWGARVAQRTVLPLVASRYQFEDER-LKQRLWGDTFPNPVGL 62
Query: 342 AAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGH 521
AAG DK+ AV +GF +EVGSV+ QP PGNP PR FRLP+D A+INR G N+ G
Sbjct: 63 AAGADKNARAVPFWEAVGFGFVEVGSVSAQPAPGNPTPRAFRLPKDQALINRLGLNNDGA 122
Query: 522 DEVYKKLEGIEKAVMNRAL-LGVNLGKNKLSDDAGK 626
+ V +L E + +RA LG+NL K D G+
Sbjct: 123 EAVADRL---EHSRSDRARPLGINLAKTHDPDIMGE 155
>UniRef50_A3J5I9 Cluster: Dihydroorotate dehydrogenase; n=19;
Bacteroidetes/Chlorobi group|Rep: Dihydroorotate
dehydrogenase - Flavobacteria bacterium BAL38
Length = 362
Score = 96.7 bits (230), Expect = 4e-19
Identities = 61/166 (36%), Positives = 88/166 (53%), Gaps = 10/166 (6%)
Frame = +3
Query: 165 NSYYENVLQPLSQYLSPEVAHRIGVAAIKH--------GLFPPDQNEDPKILKTRLLDYD 320
++ Y+ ++PL PE H + I+ GLF L+ +
Sbjct: 23 HTMYKIFIRPLLFCFDPEKVHYFTFSLIRFLNKIPGFSGLFQALYEVKDARLEREVFGIK 82
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRY 500
NP+G+AAGFDK L GF IE+G++TP Q GNPK R+FRL ED A+INR
Sbjct: 83 FKNPVGLAAGFDKDAKLYQELSNFGFGFIEIGTLTPVGQEGNPKKRLFRLKEDNAIINRM 142
Query: 501 GFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKL--SDDAGKDY 632
GFN+ G E ++L+ K V L+G N+GKNK+ +++A +DY
Sbjct: 143 GFNNGGVKEAVERLKK-NKGV----LIGGNIGKNKVTPNEEAVQDY 183
>UniRef50_Q0U3U0 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 549
Score = 96.7 bits (230), Expect = 4e-19
Identities = 55/133 (41%), Positives = 78/133 (58%), Gaps = 8/133 (6%)
Frame = +3
Query: 168 SYYENVLQPLSQYLSP--EVAHRIGVAAIK----HGLFPPDQNEDPKI--LKTRLLDYDL 323
S +E +L P + + P E AH G A +K G+ P ++ L + + L
Sbjct: 76 SIHEWLLVPALRQIYPDGEDAHHAGTAMLKALHSFGMNPRERGPGDSAGDLAVEVFGHTL 135
Query: 324 SNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYG 503
+NP+G +AG DK+ + L +LG +I+EVG+VT PQ GNPKPRVFR+P A+INRYG
Sbjct: 136 ANPIGTSAGIDKNAEVPTPLFELGPAIVEVGAVTLLPQEGNPKPRVFRIPSQNALINRYG 195
Query: 504 FNSIGHDEVYKKL 542
FNS G + V +L
Sbjct: 196 FNSEGAELVATRL 208
>UniRef50_Q9RX14 Cluster: Dihydroorotate dehydrogenase; n=4;
Bacteria|Rep: Dihydroorotate dehydrogenase - Deinococcus
radiodurans
Length = 369
Score = 95.5 bits (227), Expect = 1e-18
Identities = 49/104 (47%), Positives = 68/104 (65%), Gaps = 2/104 (1%)
Frame = +3
Query: 327 NPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGF 506
+PLG+AAG DK+ AV GF +EVG+VTP Q GN +PR+FRLPED A+INR GF
Sbjct: 70 SPLGLAAGLDKNAQAVPAFTAFGFGFVEVGTVTPLAQSGNERPRLFRLPEDEALINRMGF 129
Query: 507 NSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKL--SDDAGKDY 632
N+ G ++ +L + A + VN+GKNK+ ++DA +DY
Sbjct: 130 NNGGTAAMHARLAVLTD---RAAPVWVNIGKNKVTPNEDAAEDY 170
>UniRef50_Q7S895 Cluster: Putative uncharacterized protein
NCU06532.1; n=2; Sordariomycetes|Rep: Putative
uncharacterized protein NCU06532.1 - Neurospora crassa
Length = 500
Score = 95.1 bits (226), Expect = 1e-18
Identities = 60/163 (36%), Positives = 87/163 (53%), Gaps = 9/163 (5%)
Frame = +3
Query: 168 SYYENVLQPLSQYLSP--EVAHRIGVAAIKHGLFPPDQN------EDPK-ILKTRLLDYD 320
S ++ ++ PL + + P E AH +G AA+K GL+ + E P L +
Sbjct: 98 SVHQYLVPPLLRTIFPDAEEAHHVGTAALK-GLYETGLHIRERVPESPNGPLSVNVFGKQ 156
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRY 500
L NP+GI+AG DK + L LG ++EVG TP PQ GNPKPRVFR+P +INRY
Sbjct: 157 LLNPIGISAGLDKDAEIPDPLFALGAGVVEVGGCTPFPQEGNPKPRVFRIPSVDGLINRY 216
Query: 501 GFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAGKD 629
G NS G D + +L + + + V L N++ ++ G D
Sbjct: 217 GLNSRGADAMATRL----RERLRKFARSVGLTDNEVLNEEGTD 255
>UniRef50_A0H696 Cluster: Dihydroorotate oxidase; n=2;
Chloroflexus|Rep: Dihydroorotate oxidase - Chloroflexus
aggregans DSM 9485
Length = 376
Score = 93.9 bits (223), Expect = 3e-18
Identities = 47/110 (42%), Positives = 71/110 (64%)
Frame = +3
Query: 282 DPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRV 461
D ++ +T + NP+G+AAG DK G A+ LGF +EVG+VT PQPGNP+PR+
Sbjct: 70 DQRLSRT-VFGVQFPNPVGLAAGMDKDGVALPAWAALGFGFVEVGTVTHLPQPGNPRPRL 128
Query: 462 FRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS 611
FRLP A+INR GFN+ G + +L ++ A + +GV++GK+K++
Sbjct: 129 FRLPTHEALINRMGFNNAGAAALAHRLASLQPAPVP---VGVSIGKSKVT 175
>UniRef50_P74782 Cluster: Dihydroorotate dehydrogenase; n=12;
Bacteria|Rep: Dihydroorotate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 381
Score = 93.5 bits (222), Expect = 4e-18
Identities = 58/163 (35%), Positives = 87/163 (53%), Gaps = 2/163 (1%)
Frame = +3
Query: 153 KKDFNSYYENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNP 332
K D ++ ++Q L + + HR G A L + DP++ +T + N
Sbjct: 17 KSDPERGHQRLIQTLKKV---DTMHRNGFAVAMEQLEQAFTHADPRLQQT-CWGLNFPNV 72
Query: 333 LGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNS 512
LG++AG DK G+A LGF E+G+VT QPGN +PR+FRLP+D AV+NR G N+
Sbjct: 73 LGLSAGCDKEGEAAAVWPALGFGFAELGAVTKYAQPGNDRPRLFRLPQDQAVLNRLGANN 132
Query: 513 IGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLS--DDAGKDYV 635
G + KL+ +G+NL K+K++ D A +DYV
Sbjct: 133 EGAVAMAAKLKHTWDYYPRTIPIGINLCKSKITPLDQAVEDYV 175
>UniRef50_Q8FTC6 Cluster: Dihydroorotate dehydrogenase; n=35;
Bacteria|Rep: Dihydroorotate dehydrogenase -
Corynebacterium efficiens
Length = 377
Score = 93.5 bits (222), Expect = 4e-18
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 2/119 (1%)
Frame = +3
Query: 282 DPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRV 461
DP +L + PLG+AAGFDK+ A LGF E+G+VT PQ GNP PR+
Sbjct: 62 DP-VLSQEVFGVTFPRPLGLAAGFDKNATAADTWTALGFGYAELGTVTASPQAGNPTPRL 120
Query: 462 FRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKL--SDDAGKDY 632
FRLP D A++NR GFN+ G +V L + +R ++G+N+GK K+ ++ A DY
Sbjct: 121 FRLPADRAILNRMGFNNAGAADVADNL----RRRKSRDVIGINIGKTKVVPAEQAVDDY 175
>UniRef50_Q5YVM8 Cluster: Dihydroorotate dehydrogenase; n=6;
Bacteria|Rep: Dihydroorotate dehydrogenase - Nocardia
farcinica
Length = 369
Score = 90.6 bits (215), Expect = 3e-17
Identities = 48/114 (42%), Positives = 65/114 (57%)
Frame = +3
Query: 282 DPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRV 461
D IL + + PLG+AAGFDK+ + V G+ E+G+VT Q QPGNP PR+
Sbjct: 45 DDPILHSTVFGVPFRAPLGLAAGFDKNAEGVDVWGPFGWGFAEIGTVTAQAQPGNPAPRL 104
Query: 462 FRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAG 623
FRLP D A+INR GFN+ G ++L V +G N+GK K+ + AG
Sbjct: 105 FRLPADRALINRMGFNNHGAARAAEQLRARTATVP----IGANIGKTKVVEPAG 154
>UniRef50_A7GYB2 Cluster: Dihydroorotate oxidase; n=7;
Campylobacterales|Rep: Dihydroorotate oxidase -
Campylobacter curvus 525.92
Length = 357
Score = 87.4 bits (207), Expect = 3e-16
Identities = 57/159 (35%), Positives = 88/159 (55%), Gaps = 12/159 (7%)
Frame = +3
Query: 213 PEVAHRIGVAAI--KHGLFPPDQN--------EDPKILKTRLLDYDLSNPLGIAAGFDKH 362
PE AH+I A+ + +FP + D K L+ LL +NP+GI GFDK+
Sbjct: 17 PETAHKIAELAMIWSNKIFPGSLSLVASKCVINDAK-LQQNLLGSIYNNPVGIGGGFDKN 75
Query: 363 GDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
+ L LGF +E G+ TP+PQ GN KPR+FRL E+ ++ N GFN+ G + + ++
Sbjct: 76 ATMLPALCALGFGYLEFGTFTPKPQSGNDKPRLFRLIEEQSIQNAMGFNNEGCEPIKQR- 134
Query: 543 EGIEKAVMNRALLGVNLGKNKL--SDDAGKDYVSGIEKF 653
++K+ L N+GKNKL +++A DY + +F
Sbjct: 135 --VKKSYPFVVPLWANIGKNKLTPNENAIDDYEILVREF 171
>UniRef50_Q64UC1 Cluster: Dihydroorotate dehydrogenase; n=3;
Bacteroides|Rep: Dihydroorotate dehydrogenase -
Bacteroides fragilis
Length = 331
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/153 (36%), Positives = 88/153 (57%), Gaps = 6/153 (3%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKT----RLLDYDLS--NPL 335
Y+ ++P+ + PE H + V+ +K P + L T +L+ L+ N +
Sbjct: 2 YKQTIRPVLFLMEPEKVHALLVSCLKCYRHLPWCRCWMRHLYTCSDKQLIWNHLTFRNRI 61
Query: 336 GIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSI 515
G++AGFDK + L GF IEVG+VTP Q GNP+PR+FRLP+ ++I+R GFN+
Sbjct: 62 GLSAGFDKGAEIFDELADCGFGFIEVGTVTPDSQDGNPRPRIFRLPQCESLISRTGFNNP 121
Query: 516 GHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSD 614
G D + ++LE +K+ +LGVN+ KN S+
Sbjct: 122 GLDVIKRRLE--QKS--GSYVLGVNINKNPSSE 150
>UniRef50_Q2H299 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 596
Score = 86.6 bits (205), Expect = 5e-16
Identities = 60/179 (33%), Positives = 84/179 (46%), Gaps = 16/179 (8%)
Frame = +3
Query: 54 TTTMSQKKDPLKKIRSLCYVTXXXXXXXXXXXXKKDFNSYYENVLQP-LSQYLSPEV--A 224
T + S K+ P R++ T D + L P L + L P+ A
Sbjct: 173 TASSSAKRTP-STARNVFLTTLLATTATVTYYYATDTRASIHQWLVPRLIRVLFPDAEDA 231
Query: 225 HRIGVAAIKH----GLFPPDQNEDPKI---------LKTRLLDYDLSNPLGIAAGFDKHG 365
H G AA+K GL P ++ P+ L + L+NP+GI+AG DK
Sbjct: 232 HHAGTAALKTLYPLGLHPRERPPFPEDAHPATGTNPLAVTVFGTTLANPIGISAGLDKDA 291
Query: 366 DAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKL 542
+ L LG ++EVG TP PQ GNP+PRVFR+P ++NRYG NS G D + +L
Sbjct: 292 EIADPLFALGAGVVEVGGCTPLPQAGNPRPRVFRVPAVDGLVNRYGLNSRGADAMAARL 350
>UniRef50_Q5UYF1 Cluster: Dihydroorotate dehydrogenase; n=7;
Halobacteriaceae|Rep: Dihydroorotate dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 350
Score = 82.2 bits (194), Expect = 1e-14
Identities = 44/115 (38%), Positives = 65/115 (56%), Gaps = 2/115 (1%)
Frame = +3
Query: 294 LKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLP 473
L + NP+G+AAGFDK+ L LGF EVG VT +PQ GN +PR+FRL
Sbjct: 50 LAVEAFGHTFDNPVGVAAGFDKNATIPETLASLGFGFAEVGGVTAEPQAGNARPRMFRLK 109
Query: 474 EDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKL--SDDAGKDY 632
D A+INR G N+ G + ++L+ ++ +GVN+ K + +++A DY
Sbjct: 110 ADEAIINRMGLNNDGAIVIGERLKNVDAPFP----VGVNIAKTEHVGTNEAPDDY 160
>UniRef50_O25655 Cluster: Dihydroorotate dehydrogenase; n=15;
Campylobacterales|Rep: Dihydroorotate dehydrogenase -
Helicobacter pylori (Campylobacter pylori)
Length = 351
Score = 81.4 bits (192), Expect = 2e-14
Identities = 45/126 (35%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Frame = +3
Query: 279 EDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPR 458
++PK L+ +L NPLG+AAGFDK+ + LM GF +E G++T + Q GN +PR
Sbjct: 46 QNPK-LENEILGLHFPNPLGLAAGFDKNASMLRALMAFGFGYLEAGTLTNEAQVGNERPR 104
Query: 459 VFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAG--KDY 632
+FR E+ ++ N GFN+ G + ++ + +G+NLGKNK + A +DY
Sbjct: 105 LFRHIEEESLQNAMGFNNYG---AILGVRSFKRFAPYKTPIGINLGKNKHIEQAHALEDY 161
Query: 633 VSGIEK 650
+ + K
Sbjct: 162 KAVLSK 167
>UniRef50_A3ZNL9 Cluster: Dihydroorotate dehydrogenase; n=2;
Planctomycetaceae|Rep: Dihydroorotate dehydrogenase -
Blastopirellula marina DSM 3645
Length = 372
Score = 78.2 bits (184), Expect = 2e-13
Identities = 53/157 (33%), Positives = 82/157 (52%), Gaps = 8/157 (5%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIK-HGLFP--PD-----QNEDPKILKTRLLDYDLSN 329
Y ++L+PL + E AH +AA + G P P + L++ + N
Sbjct: 4 YRSILRPLLFHWDAETAHHATIAACRIAGAIPLAPQLMRAWYDFAASPLESNVAGLTFPN 63
Query: 330 PLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFN 509
P+G+AAG+DK+G A+ L GF E+GS++ GN +PR+FRLP+D A++ YG
Sbjct: 64 PVGLAAGWDKNGHALRLLDSWGFGFAEIGSISAAASLGNRRPRLFRLPQDRAIVVNYGLP 123
Query: 510 SIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDA 620
+ G + + ++L K + R LGVNL K DA
Sbjct: 124 NDGAEVIAQRL---AKHRIRRP-LGVNLVKTNQGPDA 156
>UniRef50_Q8G505 Cluster: Dihydroorotate dehydrogenase-like protein;
n=4; Bifidobacterium|Rep: Dihydroorotate
dehydrogenase-like protein - Bifidobacterium longum
Length = 338
Score = 77.0 bits (181), Expect = 4e-13
Identities = 46/124 (37%), Positives = 68/124 (54%)
Frame = +3
Query: 282 DPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRV 461
DP IL+T ++ D +NP G++AG DK+ + V L GF VGS T +P PGN KP
Sbjct: 26 DP-ILETNVMGVDFTNPFGLSAGLDKNCEMPVVLDHAGFGFETVGSTTSRPCPGNAKPWF 84
Query: 462 FRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAGKDYVSG 641
RLPE +++ G +IG D+V +E EKA + +++ + +DD D G
Sbjct: 85 HRLPEYDSMMVHVGLANIGSDKV---IERAEKAWTQARQMQLSVSIARTNDDQCGDLDEG 141
Query: 642 IEKF 653
IE +
Sbjct: 142 IEDY 145
>UniRef50_Q2IVE7 Cluster: Dihydroorotate oxidase; n=1;
Rhodopseudomonas palustris HaA2|Rep: Dihydroorotate
oxidase - Rhodopseudomonas palustris (strain HaA2)
Length = 348
Score = 70.9 bits (166), Expect = 2e-11
Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Frame = +3
Query: 174 YENVLQPLSQYLSPEVAHRIGVAAIKHGL-------FPPDQNEDPKILKTRLLDYDLSNP 332
Y ++L P +SP+ +H + AA++ + + +DP+++ TR +L NP
Sbjct: 4 YRDLLAPGLFRMSPDRSHAMAHAALRRAVPWRLLAAAATLRVDDPRLV-TRFAGVELPNP 62
Query: 333 LGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNS 512
+G+AAGFDK + + L LGF + VGS+ P+P+ GNP PR+ R ++ + G S
Sbjct: 63 VGLAAGFDKDAELIAALSCLGFGFVCVGSIMPEPRVGNPFPRLVRRRGTESIADSMGVPS 122
Query: 513 IGHDEVYKKL 542
G ++L
Sbjct: 123 KGRAYATERL 132
>UniRef50_Q6MPX3 Cluster: PyrD protein; n=1; Bdellovibrio
bacteriovorus|Rep: PyrD protein - Bdellovibrio
bacteriovorus
Length = 327
Score = 69.7 bits (163), Expect = 6e-11
Identities = 42/114 (36%), Positives = 66/114 (57%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 DLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINR 497
+ +NP+GIA G DK+ + + LG +EVG++TP+ Q NP + R E A+ N+
Sbjct: 43 EFANPMGIAGGVDKNAEHLKEWWALGCGFVEVGTITPRAQTPNPGKIMDRDLELQAMWNK 102
Query: 498 YGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNK--LSDDAGKDYVSGIEKF 653
GF S G DEV+ L A R + VN+GKN+ ++DA DY++ +++F
Sbjct: 103 MGFPSDGGDEVFHNLASY--APNYRTPIFVNIGKNRHTPNNDAVADYLTLVDQF 154
>UniRef50_A3H775 Cluster: Dihydroorotate oxidase; n=1; Caldivirga
maquilingensis IC-167|Rep: Dihydroorotate oxidase -
Caldivirga maquilingensis IC-167
Length = 322
Score = 60.5 bits (140), Expect = 3e-08
Identities = 32/76 (42%), Positives = 45/76 (59%)
Frame = +3
Query: 297 KTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPE 476
+ RLL+ + +P+GI AG DK G + + +L VGSVT +P+ GNPKPR+ R P
Sbjct: 45 RLRLLNRVIDSPIGIGAGIDKDGLLISLMSRLPIGFHIVGSVTLKPRRGNPKPRMRRYPG 104
Query: 477 DGAVINRYGFNSIGHD 524
A++N G S G D
Sbjct: 105 LDAMVNAMGLPSRGVD 120
>UniRef50_Q8ZTG4 Cluster: Dihydroorotate dehydrogenase; n=4;
Pyrobaculum|Rep: Dihydroorotate dehydrogenase -
Pyrobaculum aerophilum
Length = 297
Score = 50.0 bits (114), Expect = 5e-05
Identities = 38/116 (32%), Positives = 54/116 (46%)
Frame = +3
Query: 204 YLSPEVAHRIGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGL 383
Y+ PE+AHR+G L P + E + + P+G+AAG DK G L
Sbjct: 13 YIHPEIAHRLGALLFSIPL-PSCKCER----SWEIGGVKVCGPVGVAAGLDKTGLYSRFL 67
Query: 384 MKLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGI 551
I VGS P+ + GN PR RL +++N G NS G +V +L G+
Sbjct: 68 SFFCPGFIVVGSTLPRARRGNRPPRAARL-RPYSMVNAMGLNSPGIAKVVSRLRGL 122
>UniRef50_A0DS83 Cluster: Chromosome undetermined scaffold_61, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_61,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 388
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQ 431
L N LG+A+GFD G V L LGF IE+GS+T Q
Sbjct: 79 LKNQLGLASGFDNDGSFVETLQNLGFGFIEIGSITAQ 115
>UniRef50_Q73P17 Cluster: Dihydroorotate
dehydrogenase/oxidoreductase, FAD-binding; n=1;
Treponema denticola|Rep: Dihydroorotate
dehydrogenase/oxidoreductase, FAD-binding - Treponema
denticola
Length = 591
Score = 38.7 bits (86), Expect = 0.12
Identities = 21/76 (27%), Positives = 37/76 (48%)
Frame = +3
Query: 387 KLGFSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVM 566
+LGF ++ S P PGN +P + PE G N G + G ++ K+L+ + +
Sbjct: 47 ELGFGLVTTKSFQVLPNPGNREP-ILCEPELGCFGNSVGLRNCGMEQAVKELKELRSSWK 105
Query: 567 NRALLGVNLGKNKLSD 614
++L V+L + D
Sbjct: 106 TDSILNVSLSASNPED 121
>UniRef50_Q11LN4 Cluster: Flagellin-like; n=6; Rhizobiales|Rep:
Flagellin-like - Mesorhizobium sp. (strain BNC1)
Length = 293
Score = 38.7 bits (86), Expect = 0.12
Identities = 31/115 (26%), Positives = 48/115 (41%)
Frame = +3
Query: 300 TRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPED 479
T +L D + PL IAA +++ D G + +G +++ +T G L D
Sbjct: 132 TNILATDSAGPLDIAASYNRASD---GTVSIGTISVDLAGITLFAADGTTTDATQHLAHD 188
Query: 480 GAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNKLSDDAGKDYVSGI 644
I+ + Y LE IE A+ + NLG K D KD+VS +
Sbjct: 189 VMQIDLVANGDEASIDAY--LEDIETALAAMSTAAANLGSAKNRLDLQKDFVSNL 241
>UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family
protein; n=21; Bacteria|Rep: Dihydroorotate
dehydrogenase family protein - Dehalococcoides sp. BAV1
Length = 324
Score = 35.9 bits (79), Expect = 0.85
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Frame = +3
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLG-FSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINR 497
LSNP+ A+G +GD L I + T +P+ GNP+PR+ P ++N
Sbjct: 34 LSNPVMAASGTFGYGDEYPHLFDRNRLGAIVCKATTLKPREGNPQPRIAETP--NGMLNS 91
Query: 498 YGFNSIGHDEVYK 536
G ++G + V +
Sbjct: 92 IGLQNMGVEAVIR 104
>UniRef50_A5NSG9 Cluster: Dihydroorotate dehydrogenase family
protein; n=5; Proteobacteria|Rep: Dihydroorotate
dehydrogenase family protein - Methylobacterium sp. 4-46
Length = 351
Score = 35.5 bits (78), Expect = 1.1
Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +3
Query: 294 LKTRLLDYDLSNPLGIAAGFDKHG-DAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRL 470
L R+ L NP+ A+G G D V+ + +LG + + ++T + + GNP PRV
Sbjct: 40 LSVRIGRLTLRNPVMPASGTFAEGLDRVIDVNRLGAVVTK--TITRELRTGNPLPRVVER 97
Query: 471 PEDGAVINRYGFNSIG 518
P G +IN G S G
Sbjct: 98 P--GGLINAIGIPSKG 111
>UniRef50_Q4DGY9 Cluster: Dihydroorotate dehydrogenase, putative;
n=1; Trypanosoma cruzi|Rep: Dihydroorotate
dehydrogenase, putative - Trypanosoma cruzi
Length = 280
Score = 35.5 bits (78), Expect = 1.1
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Frame = +3
Query: 294 LKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVG-SVTPQPQPGNPKPRVFRL 470
LK LLD+ +NP AAG + + M S V S T P+ GNP+PR +
Sbjct: 49 LKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAV 108
Query: 471 PEDGAVINRYGFNSIGHD 524
P IN G ++G D
Sbjct: 109 PLGS--INSMGLPNLGFD 124
>UniRef50_Q2KCJ6 Cluster: Sensor protein; n=2; Rhizobium|Rep: Sensor
protein - Rhizobium etli (strain CFN 42 / ATCC 51251)
Length = 531
Score = 35.1 bits (77), Expect = 1.5
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
Frame = +3
Query: 207 LSPEVAHRIGVAAIKHGLFPPDQNEDPKILK--TRLLDYDLSNPLGIAAGFDK--HGDAV 374
LSPE HR AI HG+ + + L+ TR + +DL PL F + HG AV
Sbjct: 111 LSPETLHRCIQNAIMHGMLEAQLEQKRQSLEIFTRAMAHDLKEPLRTIKSFSRILHGSAV 170
Query: 375 V 377
+
Sbjct: 171 L 171
>UniRef50_A4BME3 Cluster: Putative uncharacterized protein; n=1;
Nitrococcus mobilis Nb-231|Rep: Putative uncharacterized
protein - Nitrococcus mobilis Nb-231
Length = 216
Score = 35.1 bits (77), Expect = 1.5
Identities = 20/66 (30%), Positives = 30/66 (45%)
Frame = +3
Query: 231 IGVAAIKHGLFPPDQNEDPKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIE 410
+GV + H +P D+NE PK + D DL + GFD D V L+ +
Sbjct: 80 VGVRHLAHVTWPEDKNELPKFTFAMVADSDLDSSTLDFTGFD--SDGFVSLLAIEIEFDG 137
Query: 411 VGSVTP 428
+G+ P
Sbjct: 138 IGTFAP 143
>UniRef50_Q7S1F3 Cluster: Predicted protein; n=4;
Pezizomycotina|Rep: Predicted protein - Neurospora
crassa
Length = 332
Score = 34.7 bits (76), Expect = 2.0
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 7/57 (12%)
Frame = +2
Query: 452 AEGLPTPGGRSR-----HQQIWLQQHRARRSIQK--AGRNREGRNESGTPRRESGKE 601
AE + PGGRSR + L + AR+ I + G + GR+ S PRRE G+E
Sbjct: 191 AERITVPGGRSRSISPSRRDRDLDEEAARKGIDRYRPGGSSRGRSRSPLPRREGGRE 247
>UniRef50_Q47741 Cluster: Dihydroorotate dehydrogenase B, catalytic
subunit; n=104; Bacteria|Rep: Dihydroorotate
dehydrogenase B, catalytic subunit - Enterococcus
faecalis (Streptococcus faecalis)
Length = 312
Score = 34.7 bits (76), Expect = 2.0
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +3
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLG-FSIIEVGSVTPQPQPGNPKPRVFRLPEDGAVINR 497
L NP+ A+G G+ L I + + TPQ + GNP PRV P ++N
Sbjct: 15 LKNPIIPASGCFGFGEEYANYYDLDQLGSIMIKATTPQARYGNPTPRVAETP--SGMLNA 72
Query: 498 YGFNSIGHDEV-YKKLEGIEK 557
G + G + V +KL +EK
Sbjct: 73 IGLQNPGLEVVMQEKLPKLEK 93
>UniRef50_UPI00015BD53C Cluster: UPI00015BD53C related cluster; n=1;
unknown|Rep: UPI00015BD53C UniRef100 entry - unknown
Length = 310
Score = 34.3 bits (75), Expect = 2.6
Identities = 24/93 (25%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Frame = +3
Query: 294 LKTRLLDYDLSNPLGIAAG---FDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVF 464
L L NP+ +A+G + G + + KLG +++ G ++ +P+ GNP PR+
Sbjct: 4 LGIELFGIKFKNPVWVASGTFGYGVEGADIYDISKLG-AVVTKG-LSLRPREGNPMPRIA 61
Query: 465 RLPEDGAVINRYGFNSIGHDEVYKKLEGIEKAV 563
P ++N G + G + KK+ + K +
Sbjct: 62 ETP--CGMLNSIGLQNPGVEAFIKKIYPVIKDI 92
>UniRef50_A4ECL7 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 302
Score = 34.3 bits (75), Expect = 2.6
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +3
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTP-----QPQPGNPKPRVFRLPEDGA 485
+ NP+ AAG +G F + ++G++T +P PGNP PR+ +P G
Sbjct: 10 MQNPINTAAGTFGYGWQFQNF----FDVSQLGAITTKGCAAEPWPGNPAPRMAEIP--GG 63
Query: 486 VINRYGFNSIG 518
+IN G + G
Sbjct: 64 MINSVGLQNPG 74
>UniRef50_A0R4B8 Cluster: Transcription regulator; n=1;
Mycobacterium smegmatis str. MC2 155|Rep: Transcription
regulator - Mycobacterium smegmatis (strain ATCC 700084
/ mc(2)155)
Length = 171
Score = 34.3 bits (75), Expect = 2.6
Identities = 24/66 (36%), Positives = 29/66 (43%)
Frame = +3
Query: 285 PKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVF 464
PK L LLD + P+GI K G + K ++E G V P PGN K
Sbjct: 51 PK-LSMHLLDAIAAGPVGIVGLAAKSGQLKGTVSKHVQRLVEAGLVVRTPVPGNRKEIEL 109
Query: 465 RLPEDG 482
RL DG
Sbjct: 110 RLTADG 115
>UniRef50_A4R249 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 421
Score = 34.3 bits (75), Expect = 2.6
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Frame = +2
Query: 401 DHRSGLGHXXXXXRESQAEGLPTPGGRSRHQQIWLQQHRARRSIQKAGRNREGR-NESGT 577
DHR G GH R+ + GLP P + H L ++ R I +G R N+S
Sbjct: 229 DHREGGGHNLAAARKGKPRGLPRPASPTAHA---LCRYDVLRMISPSGDRPSARGNQSWQ 285
Query: 578 PRRESGK 598
+R G+
Sbjct: 286 SKRFRGR 292
>UniRef50_Q2BA70 Cluster: Dihydroorotate dehydrogenase; n=1;
Bacillus sp. NRRL B-14911|Rep: Dihydroorotate
dehydrogenase - Bacillus sp. NRRL B-14911
Length = 626
Score = 33.9 bits (74), Expect = 3.4
Identities = 24/92 (26%), Positives = 41/92 (44%)
Frame = +3
Query: 285 PKILKTRLLDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVF 464
P++ KT +L Y +P+G++ D LGF +E G V+ + Q +
Sbjct: 53 PELQKT-MLGYSFQSPVGLSGKVDPLLSGTKAFTGLGFGFLEAGPVSMEVQLSSGTAVKH 111
Query: 465 RLPEDGAVINRYGFNSIGHDEVYKKLEGIEKA 560
+DG++ SIG D +LE ++ A
Sbjct: 112 ---QDGSISYPVPLESIGVDRTISQLEKMKAA 140
>UniRef50_Q1IUQ6 Cluster: Dihydroorotate dehydrogenase family
protein; n=3; Bacteria|Rep: Dihydroorotate dehydrogenase
family protein - Acidobacteria bacterium (strain
Ellin345)
Length = 321
Score = 33.5 bits (73), Expect = 4.5
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Frame = +3
Query: 267 PDQNEDPKILKTRLLDY---DLSNPLGIAAGFDKHG---DAVVGLMKLGFSIIEVGSVTP 428
P ED ++L + + L NP+ A+G +G + +V + KLG + G ++
Sbjct: 8 PKPAEDDELLFDMSVSFCGIKLKNPVLAASGTFGYGVEFEDIVTIEKLG-GFVSKG-LSR 65
Query: 429 QPQPGNPKPRVFRLPEDGAVINRYGFNSIG 518
+P PGNP PR++ ++N G +IG
Sbjct: 66 EPMPGNPPPRLWETA--AGMLNAIGLQNIG 93
>UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DSM
3091|Rep: PyrD - Methanosphaera stadtmanae (strain DSM
3091)
Length = 306
Score = 33.5 bits (73), Expect = 4.5
Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 5/124 (4%)
Frame = +3
Query: 291 ILKTRLLDYDLSNPLGIAAG-FDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFR 467
+L+ +L LSNPL +AAG ++ + + G I S + + G P + +
Sbjct: 1 MLEQEILGMKLSNPLFLAAGILGTTASSMKMVARAGAGGIVTKSFSIEANDGYDNPTIVK 60
Query: 468 LPEDGAVINRYGFNSIGHDEVYKKLEGIEKAVMNRALLGVNLGKNK--LSDDAG--KDYV 635
+ +G VIN G S G + ++L+ + + ++ G ++ SD A KDYV
Sbjct: 61 I--EGGVINSVGLASPGVEAKKEELKDLNEIRDKTPVIASIYGDSEEVFSDVANQTKDYV 118
Query: 636 SGIE 647
E
Sbjct: 119 DAFE 122
>UniRef50_UPI0000D557BD Cluster: PREDICTED: similar to CG8831-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG8831-PA - Tribolium castaneum
Length = 642
Score = 33.1 bits (72), Expect = 6.0
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 5/87 (5%)
Frame = -2
Query: 577 SARFITAFSIP---SSFLYTSSCPMLLKPYLLMT--APSSGSRKTLGLGFPGCGCGVTEP 413
S F + F P S F T P P T AP+S S T G GF G
Sbjct: 26 STGFGSTFGAPAQSSGFGSTFGTPATSTPAFGSTFGAPASTSAPTFGTGFGQSTGGGLFG 85
Query: 412 TSMIEKPSFIRPTTASPCLSNPAAMPS 332
TS + F PTT++ S P++ PS
Sbjct: 86 TSTTKPTLFGTPTTSTSLFSTPSSAPS 112
>UniRef50_UPI000038D93A Cluster: COG0642: Signal transduction
histidine kinase; n=3; Nostoc punctiforme PCC 73102|Rep:
COG0642: Signal transduction histidine kinase - Nostoc
punctiforme PCC 73102
Length = 989
Score = 33.1 bits (72), Expect = 6.0
Identities = 21/64 (32%), Positives = 31/64 (48%)
Frame = -2
Query: 511 LLKPYLLMTAPSSGSRKTLGLGFPGCGCGVTEPTSMIEKPSFIRPTTASPCLSNPAAMPS 332
L P LLMT +S K +GL G + +P + E + IR P +++P + S
Sbjct: 71 LQMPILLMTGRNSSHEKAIGLD-AGADDYLVKPFDIEELVARIRALLRRPAVTSPPVLES 129
Query: 331 GLLR 320
G LR
Sbjct: 130 GKLR 133
>UniRef50_Q24CB5 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 388
Score = 33.1 bits (72), Expect = 6.0
Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +3
Query: 162 FN-SYYENVLQPLSQYLSPEVAHRIGVAAIKHGLFPP-DQNEDPKILKTRLLDYDLSNPL 335
FN +Y Q + + S E+A+ + ++ LF D+++ K L + L N +
Sbjct: 27 FNFDFYNLFYQFVQKVYSTELAYSVTQQLMRMELFYQIDRDQYTKNLCGEISGIFLPNII 86
Query: 336 GIAAGFDKHGDAVVGLMKLGFSIIEVGSVT 425
G+ G D G + L +GF +E+G ++
Sbjct: 87 GLEEGNDLSGKQLESLFDIGFGFVEIGPLS 116
>UniRef50_Q4PE03 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1161
Score = 33.1 bits (72), Expect = 6.0
Identities = 17/47 (36%), Positives = 22/47 (46%)
Frame = -2
Query: 457 LGLGFPGCGCGVTEPTSMIEKPSFIRPTTASPCLSNPAAMPSGLLRS 317
L G G G G S +E+P + T+ +P L PA P LL S
Sbjct: 851 LDAGGAGAGAGAGASGSRLERPEHLTSTSLAPTLLKPAITPRQLLTS 897
>UniRef50_UPI0000DAE5CB Cluster: hypothetical protein
Rgryl_01000728; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000728 - Rickettsiella
grylli
Length = 355
Score = 32.7 bits (71), Expect = 7.9
Identities = 16/57 (28%), Positives = 29/57 (50%)
Frame = +3
Query: 309 LDYDLSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVGSVTPQPQPGNPKPRVFRLPED 479
L Y L++ +G+AA G + L +LGF I+ ++ + P +P P + + D
Sbjct: 43 LGYSLASKIGVAACAVTTGKGIALLAQLGFDILTYKTIRCKAYPTHPLPNIVPIQVD 99
>UniRef50_Q14151 Cluster: Scaffold attachment factor B2; n=25;
Mammalia|Rep: Scaffold attachment factor B2 - Homo
sapiens (Human)
Length = 953
Score = 32.7 bits (71), Expect = 7.9
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Frame = +2
Query: 377 GPDETGLLDHRSGLGHXXXXXRESQAEGLPTP--GGR--SRHQQIWLQQHRARR---SIQ 535
GP E D R G G R S+ GLP P GGR H Q L++H+AR ++
Sbjct: 809 GPPERHGRDSRDGWGGYGSDKRLSEGRGLPPPPRGGRDWGEHNQ-RLEEHQARAWQGAMD 867
Query: 536 KAGRNREGRNESGTPRRESG 595
+RE G R SG
Sbjct: 868 AGAASREHARWQGGERGLSG 887
>UniRef50_Q9YFI6 Cluster: Dihydroorotate dehydrogenase; n=3;
Desulfurococcales|Rep: Dihydroorotate dehydrogenase -
Aeropyrum pernix
Length = 306
Score = 32.7 bits (71), Expect = 7.9
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +3
Query: 321 LSNPLGIAAGFDKHGDAVVGLMKLGFSIIEVG-SVTPQPQPGNPKPRVFRLPEDGAVINR 497
L P+G A+G L++ G V SVT QP+ G P+P ++ P G ++N
Sbjct: 16 LQRPVGNASGILGWEPREARLVEEGGGGFFVAKSVTYQPRKGYPQPHLY--PVAGGIVNA 73
Query: 498 YGFNSIGHDEVYKKL-EGIEKA 560
G + G E K L + +E+A
Sbjct: 74 VGLANPGFREASKMLAQTVEEA 95
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 614,304,522
Number of Sequences: 1657284
Number of extensions: 12440182
Number of successful extensions: 39994
Number of sequences better than 10.0: 98
Number of HSP's better than 10.0 without gapping: 38187
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39905
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49173558301
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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