Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P06_F_F04
(639 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR457127-1|CAG33408.1| 179|Homo sapiens SPC18 protein. 227 2e-59
BC014508-1|AAH14508.1| 179|Homo sapiens SEC11 homolog A (S. cer... 227 2e-59
BC000359-1|AAH00359.3| 179|Homo sapiens SEC11 homolog A (S. cer... 227 2e-59
AF108945-1|AAD19640.1| 179|Homo sapiens signal peptidase 18 kDa... 227 2e-59
AF061737-1|AAD17526.1| 179|Homo sapiens microsomal signal pepti... 227 2e-59
AK223224-1|BAD96944.1| 179|Homo sapiens signal peptidase comple... 226 4e-59
BC009703-1|AAH09703.1| 192|Homo sapiens SEC11 homolog C (S. cer... 221 2e-57
AF212233-1|AAK14919.1| 192|Homo sapiens microsomal signal pepti... 221 2e-57
AF090315-1|AAC36354.1| 167|Homo sapiens signal peptidase comple... 217 3e-56
AF087906-1|AAP97204.1| 188|Homo sapiens signal peptidase comple... 207 3e-53
AF147791-1|AAD55679.1| 957|Homo sapiens mucin 11 protein. 32 1.5
>CR457127-1|CAG33408.1| 179|Homo sapiens SPC18 protein.
Length = 179
Score = 227 bits (556), Expect = 2e-59
Identities = 105/122 (86%), Positives = 115/122 (94%)
Frame = +2
Query: 89 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 268
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 269 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 448
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 449 QG 454
QG
Sbjct: 128 QG 129
Score = 86.6 bits (205), Expect = 7e-17
Identities = 37/51 (72%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VLVHR
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHR 178
>BC014508-1|AAH14508.1| 179|Homo sapiens SEC11 homolog A (S.
cerevisiae) protein.
Length = 179
Score = 227 bits (556), Expect = 2e-59
Identities = 105/122 (86%), Positives = 115/122 (94%)
Frame = +2
Query: 89 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 268
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 269 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 448
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 449 QG 454
QG
Sbjct: 128 QG 129
Score = 86.6 bits (205), Expect = 7e-17
Identities = 37/51 (72%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VLVHR
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHR 178
>BC000359-1|AAH00359.3| 179|Homo sapiens SEC11 homolog A (S.
cerevisiae) protein.
Length = 179
Score = 227 bits (556), Expect = 2e-59
Identities = 105/122 (86%), Positives = 115/122 (94%)
Frame = +2
Query: 89 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 268
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 269 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 448
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 449 QG 454
QG
Sbjct: 128 QG 129
Score = 86.6 bits (205), Expect = 7e-17
Identities = 37/51 (72%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VLVHR
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHR 178
>AF108945-1|AAD19640.1| 179|Homo sapiens signal peptidase 18 kDa
subunit protein.
Length = 179
Score = 227 bits (556), Expect = 2e-59
Identities = 105/122 (86%), Positives = 115/122 (94%)
Frame = +2
Query: 89 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 268
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLCYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 269 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 448
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 449 QG 454
QG
Sbjct: 128 QG 129
Score = 85.4 bits (202), Expect = 2e-16
Identities = 36/51 (70%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKF++AVL L ++VLVHR
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFRYAVLFLLGLFVLVHR 178
>AF061737-1|AAD17526.1| 179|Homo sapiens microsomal signal
peptidase protein.
Length = 179
Score = 227 bits (556), Expect = 2e-59
Identities = 105/122 (86%), Positives = 115/122 (94%)
Frame = +2
Query: 89 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 268
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 269 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 448
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 449 QG 454
QG
Sbjct: 128 QG 129
Score = 86.6 bits (205), Expect = 7e-17
Identities = 37/51 (72%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VLVHR
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHR 178
>AK223224-1|BAD96944.1| 179|Homo sapiens signal peptidase complex
(18kD) variant protein.
Length = 179
Score = 226 bits (553), Expect = 4e-59
Identities = 105/122 (86%), Positives = 114/122 (93%)
Frame = +2
Query: 89 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 268
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVTTGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 269 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 448
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 449 QG 454
QG
Sbjct: 128 QG 129
Score = 86.6 bits (205), Expect = 7e-17
Identities = 37/51 (72%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VLVHR
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHR 178
>BC009703-1|AAH09703.1| 192|Homo sapiens SEC11 homolog C (S.
cerevisiae) protein.
Length = 192
Score = 221 bits (540), Expect = 2e-57
Identities = 100/124 (80%), Positives = 115/124 (92%)
Frame = +2
Query: 83 LFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGD 262
+F D+++MNKRQ YQVL+F MIVSSALMIWKGL+V+TGSESPIVVVLSGSMEPAFHRGD
Sbjct: 18 IFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGD 77
Query: 263 LLFLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGL 442
LLFLTN+ E+P+R GEIVVFKVEGRDIPIVHRV+K+HEK+NG +KFLTKGDNN VDDRGL
Sbjct: 78 LLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGL 137
Query: 443 YAQG 454
Y +G
Sbjct: 138 YKEG 141
Score = 85.4 bits (202), Expect = 2e-16
Identities = 38/50 (76%), Positives = 43/50 (86%)
Frame = +3
Query: 453 GQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
GQ WL KKDVVGRARGFLPYVGMVTI MN+YPKFK+A+LA + YVL+ R
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKR 190
>AF212233-1|AAK14919.1| 192|Homo sapiens microsomal signal
peptidase subunit protein.
Length = 192
Score = 221 bits (540), Expect = 2e-57
Identities = 100/124 (80%), Positives = 115/124 (92%)
Frame = +2
Query: 83 LFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGD 262
+F D+++MNKRQ YQVL+F MIVSSALMIWKGL+V+TGSESPIVVVLSGSMEPAFHRGD
Sbjct: 18 IFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGD 77
Query: 263 LLFLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGL 442
LLFLTN+ E+P+R GEIVVFKVEGRDIPIVHRV+K+HEK+NG +KFLTKGDNN VDDRGL
Sbjct: 78 LLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGL 137
Query: 443 YAQG 454
Y +G
Sbjct: 138 YKEG 141
Score = 85.4 bits (202), Expect = 2e-16
Identities = 38/50 (76%), Positives = 43/50 (86%)
Frame = +3
Query: 453 GQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
GQ WL KKDVVGRARGFLPYVGMVTI MN+YPKFK+A+LA + YVL+ R
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKR 190
>AF090315-1|AAC36354.1| 167|Homo sapiens signal peptidase complex
18 kDa subunit protein.
Length = 167
Score = 217 bits (530), Expect = 3e-56
Identities = 100/117 (85%), Positives = 110/117 (94%)
Frame = +2
Query: 104 MNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNY 283
MNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN
Sbjct: 1 MNKRQLCYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNR 60
Query: 284 PEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYAQG 454
E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY QG
Sbjct: 61 VEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQG 117
Score = 85.4 bits (202), Expect = 2e-16
Identities = 36/51 (70%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKF++AVL L ++VLVHR
Sbjct: 116 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFRYAVLFLLGLFVLVHR 166
>AF087906-1|AAP97204.1| 188|Homo sapiens signal peptidase complex
SPC-18 protein.
Length = 188
Score = 207 bits (505), Expect = 3e-53
Identities = 95/110 (86%), Positives = 105/110 (95%)
Frame = +2
Query: 125 YQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRV 304
YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN E+P+RV
Sbjct: 29 YQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRV 88
Query: 305 GEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYAQG 454
GEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY QG
Sbjct: 89 GEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQG 138
Score = 86.6 bits (205), Expect = 7e-17
Identities = 37/51 (72%), Positives = 45/51 (88%)
Frame = +3
Query: 450 RGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHR 602
+GQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VLVHR
Sbjct: 137 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHR 187
>AF147791-1|AAD55679.1| 957|Homo sapiens mucin 11 protein.
Length = 957
Score = 32.3 bits (70), Expect = 1.5
Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Frame = -1
Query: 339 SRPSTLKTTISPTRTGSSG*LVKNSKSPL*KAGSI----LPDSTTTIGLSLPVTT 187
S P + TT+SP T SSG + + S + + GS PDSTTT GLS TT
Sbjct: 329 SSPRSPATTLSPASTTSSG-VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 382
Score = 30.3 bits (65), Expect = 6.0
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Frame = -1
Query: 339 SRPSTLKTTISPTRTGSSG*LVKNSKS---PL*KAGSILPDSTTTIGLSLPVTTIKPFHI 169
S P + TT+SP S G +++ S P ++ P STTT GLS TT+
Sbjct: 607 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSP 666
Query: 168 IKAEDTIIPKLNT 130
E T+ P+ T
Sbjct: 667 GSTETTVFPRSTT 679
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,094,545
Number of Sequences: 237096
Number of extensions: 2104492
Number of successful extensions: 8384
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8177
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8383
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7028963750
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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