Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P06_F_A03
(652 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X02308-1|CAA26178.1| 313|Homo sapiens protein ( Human mRNA for ... 210 3e-54
D00596-1|BAA00472.1| 313|Homo sapiens thymidylate synthase prot... 210 3e-54
BT006811-1|AAP35457.1| 313|Homo sapiens thymidylate synthetase ... 210 3e-54
BC083512-1|AAH83512.1| 313|Homo sapiens TYMS protein protein. 210 3e-54
BC013919-1|AAH13919.1| 313|Homo sapiens thymidylate synthetase ... 210 3e-54
BC002567-1|AAH02567.1| 313|Homo sapiens thymidylate synthetase ... 210 3e-54
AK223372-1|BAD97092.1| 313|Homo sapiens thymidylate synthetase ... 210 3e-54
AB062290-1|BAB93473.1| 313|Homo sapiens thymidylate synthetase ... 210 3e-54
AB077208-1|BAB83677.1| 279|Homo sapiens thymidylate synthase pr... 179 7e-45
AB077207-1|BAB83676.1| 230|Homo sapiens thymidylate synthase pr... 50 1e-05
D00517-1|BAA00404.1| 68|Homo sapiens thymidylate synthase prot... 49 1e-05
>X02308-1|CAA26178.1| 313|Homo sapiens protein ( Human mRNA for
thymidylate synthase (EC 2.1.1.45). ).
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>D00596-1|BAA00472.1| 313|Homo sapiens thymidylate synthase
protein.
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>BT006811-1|AAP35457.1| 313|Homo sapiens thymidylate synthetase
protein.
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>BC083512-1|AAH83512.1| 313|Homo sapiens TYMS protein protein.
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>BC013919-1|AAH13919.1| 313|Homo sapiens thymidylate synthetase
protein.
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>BC002567-1|AAH02567.1| 313|Homo sapiens thymidylate synthetase
protein.
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>AK223372-1|BAD97092.1| 313|Homo sapiens thymidylate synthetase
variant protein.
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>AB062290-1|BAB93473.1| 313|Homo sapiens thymidylate synthetase
protein.
Length = 313
Score = 210 bits (513), Expect = 3e-54
Identities = 96/145 (66%), Positives = 117/145 (80%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTDYTGQGIDQLQSVIDSIKNN 652
D ++DY+GQG+DQLQ VID+IK N
Sbjct: 147 RDMESDYSGQGVDQLQRVIDTIKTN 171
>AB077208-1|BAB83677.1| 279|Homo sapiens thymidylate synthase
protein.
Length = 279
Score = 179 bits (436), Expect = 7e-45
Identities = 82/126 (65%), Positives = 100/126 (79%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHNNTLPLLTTKRVFTRGVIE 397
H E QYL I I++ G ++ DRTG GTLS+FG RYSL + PLLTTKRVF +GV+E
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLE 86
Query: 398 ELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREEGDLGPVYGFQWRHSGAKY 577
ELLW I GST++K L++KGV IWDANGSR+FLD+LGF+ REEGDLGPVYGFQWRH GA+Y
Sbjct: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146
Query: 578 IDCQTD 595
D ++D
Sbjct: 147 RDMESD 152
>AB077207-1|BAB83676.1| 230|Homo sapiens thymidylate synthase
protein.
Length = 230
Score = 49.6 bits (113), Expect = 1e-05
Identities = 22/42 (52%), Positives = 28/42 (66%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSLHN 343
H E QYL I I++ G ++ DRTG GTLS+FG RYSL +
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRD 69
Score = 37.5 bits (83), Expect = 0.041
Identities = 15/20 (75%), Positives = 18/20 (90%)
Frame = +2
Query: 593 DYTGQGIDQLQSVIDSIKNN 652
DY+GQG+DQLQ VID+IK N
Sbjct: 69 DYSGQGVDQLQRVIDTIKTN 88
>D00517-1|BAA00404.1| 68|Homo sapiens thymidylate synthase
protein.
Length = 68
Score = 49.2 bits (112), Expect = 1e-05
Identities = 22/40 (55%), Positives = 27/40 (67%)
Frame = +2
Query: 218 HDEYQYLKLIDQIIKSGDKRVDRTGVGTLSIFGAMQRYSL 337
H E QYL I I++ G ++ DRTG GTLS+FG RYSL
Sbjct: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSL 67
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,820,133
Number of Sequences: 237096
Number of extensions: 1690334
Number of successful extensions: 2679
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2627
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2670
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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