Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P04_F_H23
(654 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L38951-1|AAC41763.1| 876|Homo sapiens importin beta subunit pro... 215 9e-56
BT009797-1|AAP88799.1| 876|Homo sapiens karyopherin (importin) ... 215 9e-56
BC036703-1|AAH36703.1| 876|Homo sapiens karyopherin (importin) ... 215 9e-56
BC024045-1|AAH24045.1| 876|Homo sapiens karyopherin (importin) ... 215 9e-56
BC003572-1|AAH03572.1| 876|Homo sapiens karyopherin (importin) ... 215 9e-56
L39793-1|AAA82869.1| 876|Homo sapiens nuclear factor p97 protein. 215 1e-55
AB040942-1|BAA96033.1| 1326|Homo sapiens KIAA1509 protein protein. 32 1.6
BC131711-1|AAI31712.1| 676|Homo sapiens GRB2-associated binding... 30 6.3
AL445212-3|CAI40478.1| 3013|Homo sapiens furry homolog (Drosophi... 30 6.3
AL138692-1|CAI13379.1| 3013|Homo sapiens furry homolog (Drosophi... 30 6.3
AL137143-1|CAI12629.1| 3013|Homo sapiens furry homolog (Drosophi... 30 6.3
AL049784-1|CAB42442.1| 3012|Homo sapiens hypothetical protein pr... 30 6.3
AC002483-1|AAC35295.1| 1849|Homo sapiens WUGSC:H_248O15.1 protein. 30 6.3
AB018413-1|BAA76737.1| 676|Homo sapiens Gab2 protein. 30 6.3
AB011143-1|BAA25497.2| 683|Homo sapiens KIAA0571 protein protein. 30 6.3
Z69028-1|CAA93152.1| 494|Homo sapiens beta 2 isoform of 61kDa r... 30 8.3
L42374-1|AAC37602.1| 497|Homo sapiens protein phosphatase 2A B5... 30 8.3
BC045619-1|AAH45619.1| 497|Homo sapiens PPP2R5B protein protein. 30 8.3
AC010907-2|AAY24236.1| 391|Homo sapiens unknown protein. 30 8.3
>L38951-1|AAC41763.1| 876|Homo sapiens importin beta subunit
protein.
Length = 876
Score = 215 bits (526), Expect = 9e-56
Identities = 108/175 (61%), Positives = 130/175 (74%)
Frame = +2
Query: 128 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 307
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 308 LKNHLTSKDPTLKQQYQQRWLALAXDVRLYIKENILPAIGTXNSRPSSAAQCVAYVAVAE 487
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GT RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 488 LPVXQWNDLIPILVENVVHVQSTELKKEATLEAIGYICXDIDAEVLPERSNQILT 652
+PV QW +LIP LV NV + STE KE+TLEAIGYIC DID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
>BT009797-1|AAP88799.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 215 bits (526), Expect = 9e-56
Identities = 108/175 (61%), Positives = 130/175 (74%)
Frame = +2
Query: 128 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 307
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 308 LKNHLTSKDPTLKQQYQQRWLALAXDVRLYIKENILPAIGTXNSRPSSAAQCVAYVAVAE 487
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GT RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 488 LPVXQWNDLIPILVENVVHVQSTELKKEATLEAIGYICXDIDAEVLPERSNQILT 652
+PV QW +LIP LV NV + STE KE+TLEAIGYIC DID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
>BC036703-1|AAH36703.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 215 bits (526), Expect = 9e-56
Identities = 108/175 (61%), Positives = 130/175 (74%)
Frame = +2
Query: 128 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 307
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 308 LKNHLTSKDPTLKQQYQQRWLALAXDVRLYIKENILPAIGTXNSRPSSAAQCVAYVAVAE 487
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GT RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 488 LPVXQWNDLIPILVENVVHVQSTELKKEATLEAIGYICXDIDAEVLPERSNQILT 652
+PV QW +LIP LV NV + STE KE+TLEAIGYIC DID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
>BC024045-1|AAH24045.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 215 bits (526), Expect = 9e-56
Identities = 108/175 (61%), Positives = 130/175 (74%)
Frame = +2
Query: 128 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 307
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 308 LKNHLTSKDPTLKQQYQQRWLALAXDVRLYIKENILPAIGTXNSRPSSAAQCVAYVAVAE 487
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GT RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 488 LPVXQWNDLIPILVENVVHVQSTELKKEATLEAIGYICXDIDAEVLPERSNQILT 652
+PV QW +LIP LV NV + STE KE+TLEAIGYIC DID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
>BC003572-1|AAH03572.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 215 bits (526), Expect = 9e-56
Identities = 108/175 (61%), Positives = 130/175 (74%)
Frame = +2
Query: 128 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 307
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 308 LKNHLTSKDPTLKQQYQQRWLALAXDVRLYIKENILPAIGTXNSRPSSAAQCVAYVAVAE 487
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GT RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120
Query: 488 LPVXQWNDLIPILVENVVHVQSTELKKEATLEAIGYICXDIDAEVLPERSNQILT 652
+PV QW +LIP LV NV + STE KE+TLEAIGYIC DID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
>L39793-1|AAA82869.1| 876|Homo sapiens nuclear factor p97 protein.
Length = 876
Score = 215 bits (525), Expect = 1e-55
Identities = 108/175 (61%), Positives = 130/175 (74%)
Frame = +2
Query: 128 LTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVLLQGGNSQVARMAAGLQ 307
+ LI ILEKTVSPDR ELEAA ++L+ AA N TF+ LS VL GNSQVAR+AAGLQ
Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60
Query: 308 LKNHLTSKDPTLKQQYQQRWLALAXDVRLYIKENILPAIGTXNSRPSSAAQCVAYVAVAE 487
+KN LTSKDP +K QYQQRWLA+ + R +K +L +GT RPSSA+QCVA +A AE
Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLHTLGTETYRPSSASQCVAGIACAE 120
Query: 488 LPVXQWNDLIPILVENVVHVQSTELKKEATLEAIGYICXDIDAEVLPERSNQILT 652
+PV QW +LIP LV NV + STE KE+TLEAIGYIC DID E L ++SN+ILT
Sbjct: 121 IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILT 175
>AB040942-1|BAA96033.1| 1326|Homo sapiens KIAA1509 protein protein.
Length = 1326
Score = 32.3 bits (70), Expect = 1.6
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Frame = +2
Query: 113 HAETTLTLIQILEKTVSPDRN------ELEAAVRYLDHAATTNFTTFIKMLS----DVLL 262
H E T+ L+++ ++ + +RN E + L H T N T ++L+ L
Sbjct: 343 HKEATMELLRVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFL 402
Query: 263 QGGNSQVARMAAGLQLKNH-LTSKDPTLKQQY 355
Q N+ + A LQ++N L+S+ L QY
Sbjct: 403 QEHNTTLQTQTAKLQVENSTLSSQSAALTAQY 434
>BC131711-1|AAI31712.1| 676|Homo sapiens GRB2-associated binding
protein 2 protein.
Length = 676
Score = 30.3 bits (65), Expect = 6.3
Identities = 16/61 (26%), Positives = 29/61 (47%)
Frame = -3
Query: 352 LLFKCRIFRSEMIFQLQTSCHPSHLTVTTLEKDIGQHFDECCEICGGSMVEVSNCCFQFI 173
L F + + +F ++TS +L T E+D+ + C+ICG + E S + +
Sbjct: 73 LTFNKKELQDSFVFDIKTSERTFYLVAET-EEDMNKWVQSICQICGFNQAEESTDSLRNV 131
Query: 172 S 170
S
Sbjct: 132 S 132
>AL445212-3|CAI40478.1| 3013|Homo sapiens furry homolog (Drosophila)
protein.
Length = 3013
Score = 30.3 bits (65), Expect = 6.3
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = -2
Query: 533 FLQELVLDHSIVXLGAQLLPHTPHTVLLNLDDY 435
F+ E+V+DHS+ A LP H V L LD Y
Sbjct: 1646 FMTEMVVDHSVREDWALHLPLLLHAVFLGLDHY 1678
>AL138692-1|CAI13379.1| 3013|Homo sapiens furry homolog (Drosophila)
protein.
Length = 3013
Score = 30.3 bits (65), Expect = 6.3
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = -2
Query: 533 FLQELVLDHSIVXLGAQLLPHTPHTVLLNLDDY 435
F+ E+V+DHS+ A LP H V L LD Y
Sbjct: 1646 FMTEMVVDHSVREDWALHLPLLLHAVFLGLDHY 1678
>AL137143-1|CAI12629.1| 3013|Homo sapiens furry homolog (Drosophila)
protein.
Length = 3013
Score = 30.3 bits (65), Expect = 6.3
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = -2
Query: 533 FLQELVLDHSIVXLGAQLLPHTPHTVLLNLDDY 435
F+ E+V+DHS+ A LP H V L LD Y
Sbjct: 1646 FMTEMVVDHSVREDWALHLPLLLHAVFLGLDHY 1678
>AL049784-1|CAB42442.1| 3012|Homo sapiens hypothetical protein
protein.
Length = 3012
Score = 30.3 bits (65), Expect = 6.3
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = -2
Query: 533 FLQELVLDHSIVXLGAQLLPHTPHTVLLNLDDY 435
F+ E+V+DHS+ A LP H V L LD Y
Sbjct: 1645 FMTEMVVDHSVREDWALHLPLLLHAVFLGLDHY 1677
>AC002483-1|AAC35295.1| 1849|Homo sapiens WUGSC:H_248O15.1 protein.
Length = 1849
Score = 30.3 bits (65), Expect = 6.3
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = -2
Query: 533 FLQELVLDHSIVXLGAQLLPHTPHTVLLNLDDY 435
F+ E+V+DHS+ A LP H V L LD Y
Sbjct: 1050 FMTEMVVDHSVREDWALHLPLLLHAVFLGLDHY 1082
>AB018413-1|BAA76737.1| 676|Homo sapiens Gab2 protein.
Length = 676
Score = 30.3 bits (65), Expect = 6.3
Identities = 16/61 (26%), Positives = 29/61 (47%)
Frame = -3
Query: 352 LLFKCRIFRSEMIFQLQTSCHPSHLTVTTLEKDIGQHFDECCEICGGSMVEVSNCCFQFI 173
L F + + +F ++TS +L T E+D+ + C+ICG + E S + +
Sbjct: 73 LTFNKKELQDSFVFDIKTSERTFYLVAET-EEDMNKWVQSICQICGFNQAEESTDSLRNV 131
Query: 172 S 170
S
Sbjct: 132 S 132
>AB011143-1|BAA25497.2| 683|Homo sapiens KIAA0571 protein protein.
Length = 683
Score = 30.3 bits (65), Expect = 6.3
Identities = 16/61 (26%), Positives = 29/61 (47%)
Frame = -3
Query: 352 LLFKCRIFRSEMIFQLQTSCHPSHLTVTTLEKDIGQHFDECCEICGGSMVEVSNCCFQFI 173
L F + + +F ++TS +L T E+D+ + C+ICG + E S + +
Sbjct: 80 LTFNKKELQDSFVFDIKTSERTFYLVAET-EEDMNKWVQSICQICGFNQAEESTDSLRNV 138
Query: 172 S 170
S
Sbjct: 139 S 139
>Z69028-1|CAA93152.1| 494|Homo sapiens beta 2 isoform of 61kDa
regulatory subunit of PP2A protein.
Length = 494
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/58 (20%), Positives = 26/58 (44%)
Frame = +2
Query: 86 HKLKNSETMHAETTLTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVL 259
H +K+ HA+ ++Q LEK + + + ++Y T F+ + ++L
Sbjct: 283 HSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEIL 340
>L42374-1|AAC37602.1| 497|Homo sapiens protein phosphatase 2A
B56-beta protein.
Length = 497
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/58 (20%), Positives = 26/58 (44%)
Frame = +2
Query: 86 HKLKNSETMHAETTLTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVL 259
H +K+ HA+ ++Q LEK + + + ++Y T F+ + ++L
Sbjct: 286 HSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEIL 343
>BC045619-1|AAH45619.1| 497|Homo sapiens PPP2R5B protein protein.
Length = 497
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/58 (20%), Positives = 26/58 (44%)
Frame = +2
Query: 86 HKLKNSETMHAETTLTLIQILEKTVSPDRNELEAAVRYLDHAATTNFTTFIKMLSDVL 259
H +K+ HA+ ++Q LEK + + + ++Y T F+ + ++L
Sbjct: 286 HSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEIL 343
>AC010907-2|AAY24236.1| 391|Homo sapiens unknown protein.
Length = 391
Score = 29.9 bits (64), Expect = 8.3
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = +2
Query: 398 IKENILPAIGTXNSRPSSAAQCVAYVAVAELPVXQWNDLIPI 523
++E+ LP I +R +AA + A+AEL W+ L+P+
Sbjct: 97 LEEDKLPEIPERGTRTGAAATPEEFEAIAELKSDDWSYLVPM 138
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,908,655
Number of Sequences: 237096
Number of extensions: 1781214
Number of successful extensions: 7405
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 7273
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7405
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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