Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P03_F_P09
(655 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC019320-1|AAH19320.2| 427|Homo sapiens pseudouridylate synthas... 107 5e-23
BC009505-1|AAH09505.2| 427|Homo sapiens pseudouridylate synthas... 107 5e-23
BC002901-1|AAH02901.1| 399|Homo sapiens pseudouridylate synthas... 107 5e-23
AF116238-1|AAD21042.1| 365|Homo sapiens pseudouridine synthase ... 107 5e-23
AK055702-1|BAB70990.1| 481|Homo sapiens protein ( Homo sapiens ... 38 0.024
BC004822-1|AAH04822.1| 481|Homo sapiens pseudouridylate synthas... 38 0.041
J03250-1|AAA61207.1| 765|Homo sapiens TOP1 protein. 32 1.6
U07806-1|AAB60380.1| 761|Homo sapiens DNA topoisomerase I protein. 31 4.7
U07804-1|AAB60379.1| 761|Homo sapiens DNA topoisomerase I protein. 31 4.7
M60706-1|AAA61206.1| 765|Homo sapiens topoisomerase I protein. 31 4.7
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 31 4.7
AL035652-1|CAI19767.1| 765|Homo sapiens topoisomerase (DNA) I p... 31 4.7
AL022394-1|CAI42886.1| 765|Homo sapiens topoisomerase (DNA) I p... 31 4.7
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 30 6.3
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 30 6.3
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 30 6.3
>BC019320-1|AAH19320.2| 427|Homo sapiens pseudouridylate synthase 1
protein.
Length = 427
Score = 107 bits (256), Expect = 5e-23
Identities = 58/129 (44%), Positives = 80/129 (62%), Gaps = 4/129 (3%)
Frame = +1
Query: 280 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 450
E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ +
Sbjct: 79 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 138
Query: 451 FQRSSRTDKGVSAAEQVVSLKLPLQVNV-EXINKRLPXTIKVFAVKRVTNRFNSKSKCNA 627
FQR +RTDKGVSAA QVVSLK+ L ++ E IN LP I++ +KRVT FNSK++C+A
Sbjct: 139 FQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 198
Query: 628 RSYSYTLPT 654
R+Y Y LPT
Sbjct: 199 RTYCYLLPT 207
>BC009505-1|AAH09505.2| 427|Homo sapiens pseudouridylate synthase 1
protein.
Length = 427
Score = 107 bits (256), Expect = 5e-23
Identities = 58/129 (44%), Positives = 80/129 (62%), Gaps = 4/129 (3%)
Frame = +1
Query: 280 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 450
E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ +
Sbjct: 79 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 138
Query: 451 FQRSSRTDKGVSAAEQVVSLKLPLQVNV-EXINKRLPXTIKVFAVKRVTNRFNSKSKCNA 627
FQR +RTDKGVSAA QVVSLK+ L ++ E IN LP I++ +KRVT FNSK++C+A
Sbjct: 139 FQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 198
Query: 628 RSYSYTLPT 654
R+Y Y LPT
Sbjct: 199 RTYCYLLPT 207
>BC002901-1|AAH02901.1| 399|Homo sapiens pseudouridylate synthase 1
protein.
Length = 399
Score = 107 bits (256), Expect = 5e-23
Identities = 58/129 (44%), Positives = 80/129 (62%), Gaps = 4/129 (3%)
Frame = +1
Query: 280 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 450
E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ +
Sbjct: 51 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 110
Query: 451 FQRSSRTDKGVSAAEQVVSLKLPLQVNV-EXINKRLPXTIKVFAVKRVTNRFNSKSKCNA 627
FQR +RTDKGVSAA QVVSLK+ L ++ E IN LP I++ +KRVT FNSK++C+A
Sbjct: 111 FQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 170
Query: 628 RSYSYTLPT 654
R+Y Y LPT
Sbjct: 171 RTYCYLLPT 179
>AF116238-1|AAD21042.1| 365|Homo sapiens pseudouridine synthase 1
protein.
Length = 365
Score = 107 bits (256), Expect = 5e-23
Identities = 58/129 (44%), Positives = 80/129 (62%), Gaps = 4/129 (3%)
Frame = +1
Query: 280 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 450
E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ +
Sbjct: 17 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 76
Query: 451 FQRSSRTDKGVSAAEQVVSLKLPLQVNV-EXINKRLPXTIKVFAVKRVTNRFNSKSKCNA 627
FQR +RTDKGVSAA QVVSLK+ L ++ E IN LP I++ +KRVT FNSK++C+A
Sbjct: 77 FQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 136
Query: 628 RSYSYTLPT 654
R+Y Y LPT
Sbjct: 137 RTYCYLLPT 145
>AK055702-1|BAB70990.1| 481|Homo sapiens protein ( Homo sapiens
cDNA FLJ31140 fis, clone IMR322001218, highly similar to
Mus musculus pseudouridine synthase 3 (Pus3) mRNA. ).
Length = 481
Score = 38.3 bits (85), Expect = 0.024
Identities = 37/143 (25%), Positives = 56/143 (39%), Gaps = 23/143 (16%)
Frame = +1
Query: 292 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 471
R+ +A+ + Y G Y G + E+ Q + + R RT
Sbjct: 62 RRHVALRIAYMGWGYQGFASQENTNNTIEEKLFEALTKTRLV----ESRQTSNYHRCGRT 117
Query: 472 DKGVSAAEQVVSLKLPLQ---------VNVE--------------XINKRLPXTIKVFAV 582
DKGVSA QV+SL L Q +NV+ +N+ LP I++ A
Sbjct: 118 DKGVSAFGQVISLDLRSQFPRGRDSEDLNVKEEANAAAEEIRYTHILNRVLPPDIRILAW 177
Query: 583 KRVTNRFNSKSKCNARSYSYTLP 651
V F+++ C R+Y Y P
Sbjct: 178 APVEPSFSARFSCLERTYRYFFP 200
>BC004822-1|AAH04822.1| 481|Homo sapiens pseudouridylate synthase 3
protein.
Length = 481
Score = 37.5 bits (83), Expect = 0.041
Identities = 37/143 (25%), Positives = 55/143 (38%), Gaps = 23/143 (16%)
Frame = +1
Query: 292 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 471
R+ +A+ + Y G Y G + E+ Q + + R RT
Sbjct: 62 RRHVALRIAYMGWGYQGFASQENTNNTIEEKLFEALTKTRLV----ESRQTSNYHRCGRT 117
Query: 472 DKGVSAAEQVVSLKLPLQ---------VNVE--------------XINKRLPXTIKVFAV 582
DKGVSA QV+SL L Q NV+ +N+ LP I++ A
Sbjct: 118 DKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRILAW 177
Query: 583 KRVTNRFNSKSKCNARSYSYTLP 651
V F+++ C R+Y Y P
Sbjct: 178 APVEPSFSARFSCLERTYRYFFP 200
>J03250-1|AAA61207.1| 765|Homo sapiens TOP1 protein.
Length = 765
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 160 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 303
+DE++ +D P K+ T K+ R E + G++KKP + K KK+
Sbjct: 140 RDEDD--VDYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185
>U07806-1|AAB60380.1| 761|Homo sapiens DNA topoisomerase I protein.
Length = 761
Score = 30.7 bits (66), Expect = 4.7
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = +1
Query: 160 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 303
+DE++ D P K+ T K+ R E + G++KKP + K KK+
Sbjct: 136 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 181
>U07804-1|AAB60379.1| 761|Homo sapiens DNA topoisomerase I protein.
Length = 761
Score = 30.7 bits (66), Expect = 4.7
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = +1
Query: 160 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 303
+DE++ D P K+ T K+ R E + G++KKP + K KK+
Sbjct: 136 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 181
>M60706-1|AAA61206.1| 765|Homo sapiens topoisomerase I protein.
Length = 765
Score = 30.7 bits (66), Expect = 4.7
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = +1
Query: 160 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 303
+DE++ D P K+ T K+ R E + G++KKP + K KK+
Sbjct: 140 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 30.7 bits (66), Expect = 4.7
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Frame = -1
Query: 259 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 119
L VW PN+D +PG C + Y + H L QLP+ TASVR
Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTMQLPV-TASVR 541
>AL035652-1|CAI19767.1| 765|Homo sapiens topoisomerase (DNA) I
protein.
Length = 765
Score = 30.7 bits (66), Expect = 4.7
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = +1
Query: 160 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 303
+DE++ D P K+ T K+ R E + G++KKP + K KK+
Sbjct: 140 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185
>AL022394-1|CAI42886.1| 765|Homo sapiens topoisomerase (DNA) I
protein.
Length = 765
Score = 30.7 bits (66), Expect = 4.7
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = +1
Query: 160 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 303
+DE++ D P K+ T K+ R E + G++KKP + K KK+
Sbjct: 140 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 30.3 bits (65), Expect = 6.3
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Frame = -1
Query: 259 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 119
L VW PN+D +PG C + Y + H L QLP+ TASVR
Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV-TASVR 541
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 30.3 bits (65), Expect = 6.3
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Frame = -1
Query: 259 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 119
L VW PN+D +PG C + Y + H L QLP+ TASVR
Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV-TASVR 541
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 30.3 bits (65), Expect = 6.3
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Frame = -1
Query: 259 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 119
L VW PN+D +PG C + Y + H L QLP+ TASVR
Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV-TASVR 541
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,004,395
Number of Sequences: 237096
Number of extensions: 1803173
Number of successful extensions: 3862
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3777
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3854
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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