Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P03_F_K07
(656 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48596 Cluster: GTP cyclohydrolase I; n=6; cellular org... 138 1e-31
UniRef50_P30793 Cluster: GTP cyclohydrolase I; n=78; cellular or... 109 8e-23
UniRef50_Q19980 Cluster: GTP cyclohydrolase I; n=89; cellular or... 107 3e-22
UniRef50_Q8YLL1 Cluster: GTP cyclohydrolase I 1; n=29; Bacteria|... 102 9e-21
UniRef50_Q4SEZ7 Cluster: Chromosome 1 SCAF14609, whole genome sh... 100 6e-20
UniRef50_A6QSY1 Cluster: GTP cyclohydrolase I; n=3; cellular org... 100 6e-20
UniRef50_P51599 Cluster: GTP cyclohydrolase I; n=14; Ascomycota|... 100 6e-20
UniRef50_Q94465 Cluster: GTP cyclohydrolase I; n=2; Dictyosteliu... 100 6e-20
UniRef50_Q8KEA8 Cluster: GTP cyclohydrolase I; n=46; Bacteria|Re... 95 2e-18
UniRef50_Q2GYY2 Cluster: Putative uncharacterized protein; n=1; ... 93 5e-18
UniRef50_A6RNT4 Cluster: Putative uncharacterized protein; n=2; ... 87 3e-16
UniRef50_Q6F9M5 Cluster: GTP cyclohydrolase I; n=3; cellular org... 87 5e-16
UniRef50_A5WE14 Cluster: GTP cyclohydrolase I; n=4; Pseudomonada... 80 5e-14
UniRef50_Q9RYB4 Cluster: GTP cyclohydrolase I; n=5; Bacteria|Rep... 78 2e-13
UniRef50_A5UR68 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep... 71 2e-11
UniRef50_Q3WEZ6 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep... 71 2e-11
UniRef50_Q8G0L4 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Re... 69 8e-11
UniRef50_Q8G3S1 Cluster: GTP cyclohydrolase I; n=4; Bifidobacter... 66 5e-10
UniRef50_A7QSC6 Cluster: Chromosome chr3 scaffold_158, whole gen... 66 7e-10
UniRef50_A5EFZ1 Cluster: GTP cyclohydrolase I; n=6; Proteobacter... 65 2e-09
UniRef50_Q0CVT9 Cluster: GTP cyclohydrolase I; n=1; Aspergillus ... 64 3e-09
UniRef50_UPI0000F1DBDC Cluster: PREDICTED: similar to GTP cycloh... 62 9e-09
UniRef50_Q5NN57 Cluster: GTP cyclohydrolase I; n=4; Sphingomonad... 62 1e-08
UniRef50_O69531 Cluster: GTP cyclohydrolase I; n=98; Bacteria|Re... 62 1e-08
UniRef50_A6SZ52 Cluster: GTP cyclohydrolase I; n=2; root|Rep: GT... 62 2e-08
UniRef50_Q2Q448 Cluster: GTP cyclohydrolase I; n=1; Toxoplasma g... 60 5e-08
UniRef50_Q7VFG4 Cluster: GTP cyclohydrolase I; n=6; Helicobacter... 59 8e-08
UniRef50_Q92QB4 Cluster: GTP cyclohydrolase I; n=49; Proteobacte... 58 1e-07
UniRef50_A4QTK3 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_A2BL58 Cluster: GTP cyclohydrolase I; n=2; Thermoprotei... 58 2e-07
UniRef50_P0C0C1 Cluster: GTP cyclohydrolase I; n=23; Bacteria|Re... 57 3e-07
UniRef50_Q68WZ4 Cluster: GTP cyclohydrolase 1; n=25; Bacteria|Re... 57 3e-07
UniRef50_Q6NF93 Cluster: GTP cyclohydrolase I; n=8; Bacteria|Rep... 56 6e-07
UniRef50_A4G565 Cluster: GTP cyclohydrolase I; n=2; Betaproteoba... 56 7e-07
UniRef50_Q97D54 Cluster: GTP cyclohydrolase I; n=7; Clostridium|... 55 1e-06
UniRef50_UPI0000DADB56 Cluster: hypothetical protein RcanM_01000... 54 2e-06
UniRef50_Q82Z12 Cluster: GTP cyclohydrolase I; n=1; Enterococcus... 54 3e-06
UniRef50_Q89IW2 Cluster: GTP cyclohydrolase I; n=13; Bacteria|Re... 54 4e-06
UniRef50_A2U8J6 Cluster: GTP cyclohydrolase I; n=2; Bacillus|Rep... 53 5e-06
UniRef50_Q971G9 Cluster: GTP cyclohydrolase I; n=4; Sulfolobacea... 53 7e-06
UniRef50_Q01A10 Cluster: GTP cyclohydrolase I; n=2; Ostreococcus... 52 1e-05
UniRef50_Q1IAJ6 Cluster: Putative GTP cyclohydrolase I; n=1; Pse... 52 2e-05
UniRef50_Q5HBC9 Cluster: GTP cyclohydrolase I; n=4; canis group|... 51 2e-05
UniRef50_Q88ST4 Cluster: GTP cyclohydrolase I; n=11; Lactobacill... 51 2e-05
UniRef50_Q9PC02 Cluster: GTP cyclohydrolase I; n=16; Bacteria|Re... 50 5e-05
UniRef50_A0RYT5 Cluster: GTP cyclohydrolase I; n=2; Thermoprotei... 50 6e-05
UniRef50_Q2GK14 Cluster: GTP cyclohydrolase I; n=2; Anaplasma ph... 49 1e-04
UniRef50_Q8S3C2 Cluster: GTP cyclohydrolase I; n=7; core eudicot... 49 1e-04
UniRef50_Q5V5Y0 Cluster: GTP cyclohydrolase I; n=1; Haloarcula m... 48 3e-04
UniRef50_Q8ZWW5 Cluster: GTP cyclohydrolase I; n=4; Pyrobaculum|... 47 3e-04
UniRef50_Q8T649 Cluster: GTP cyclohydrolase I; n=3; Plasmodium y... 46 6e-04
UniRef50_UPI00015BB290 Cluster: GTP cyclohydrolase; n=1; Ignicoc... 46 8e-04
UniRef50_Q1FI35 Cluster: GTP cyclohydrolase I; n=1; Clostridium ... 45 0.001
UniRef50_Q2JC68 Cluster: GTP cyclohydrolase I; n=1; Frankia sp. ... 45 0.002
UniRef50_Q6SIF0 Cluster: GTP cyclohydrolase I; n=1; Plasmodium k... 44 0.004
UniRef50_O97071 Cluster: GTP cyclohydrolase I; n=6; Plasmodium|R... 40 0.040
UniRef50_Q54768 Cluster: Putative uncharacterized protein; n=1; ... 40 0.069
UniRef50_A5K040 Cluster: GTP cyclohydrolase I, putative; n=1; Pl... 40 0.069
UniRef50_A0YW77 Cluster: GTP cyclohydrolase I; n=1; Lyngbya sp. ... 39 0.12
UniRef50_Q8RH43 Cluster: GTP cyclohydrolase I; n=3; Fusobacteriu... 38 0.28
UniRef50_A1SM21 Cluster: GTP cyclohydrolase I precursor; n=7; Ac... 37 0.49
UniRef50_Q5PAR5 Cluster: GTP cyclohydrolase; n=1; Anaplasma marg... 36 0.65
UniRef50_A7HBJ5 Cluster: GTP cyclohydrolase I; n=2; Anaeromyxoba... 35 2.0
UniRef50_Q4EE10 Cluster: GTP cyclohydrolase I; n=1; Listeria mon... 34 2.6
UniRef50_A4CGT7 Cluster: GTP cyclohydrolase I; n=1; Robiginitale... 34 3.5
UniRef50_Q54HA9 Cluster: Pre-mRNA processing factor 31; n=1; Dic... 34 3.5
UniRef50_Q753L6 Cluster: AFR296Cp; n=2; Saccharomycetaceae|Rep: ... 34 3.5
UniRef50_Q73PN7 Cluster: Conserved domain protein; n=1; Treponem... 33 4.6
UniRef50_Q83FV8 Cluster: GTP cyclohydrolase I; n=2; Tropheryma w... 33 8.0
>UniRef50_P48596 Cluster: GTP cyclohydrolase I; n=6; cellular
organisms|Rep: GTP cyclohydrolase I - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 138 bits (334), Expect = 1e-31
Identities = 65/84 (77%), Positives = 71/84 (84%)
Frame = +1
Query: 403 PPGXALLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAI 582
P ALLPDMA SYRLLL GLGE+P+R GL+ TPERAAKAML+FTKGYDQSLE+VLN A+
Sbjct: 135 PTREALLPDMARSYRLLLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQSLEDVLNGAV 194
Query: 583 FDEXTDXMVVVXDIXMFSMCEHHL 654
FDE D MVVV DI MFSMCEHHL
Sbjct: 195 FDEDHDEMVVVKDIEMFSMCEHHL 218
Score = 48.0 bits (109), Expect = 2e-04
Identities = 17/24 (70%), Positives = 20/24 (83%)
Frame = +3
Query: 351 GHENCTFHHDLXLDHRPPTRXGVV 422
GHE CTFHHDL LDH+PPTR ++
Sbjct: 118 GHEKCTFHHDLELDHKPPTREALL 141
>UniRef50_P30793 Cluster: GTP cyclohydrolase I; n=78; cellular
organisms|Rep: GTP cyclohydrolase I - Homo sapiens
(Human)
Length = 250
Score = 109 bits (261), Expect = 8e-23
Identities = 49/78 (62%), Positives = 62/78 (79%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD 600
LP++A +Y +L+ LGE+P+R GLL TP RAA AM FFTKGY +++ +VLN+AIFDE D
Sbjct: 68 LPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHD 127
Query: 601 XMVVVXDIXMFSMCEHHL 654
MV+V DI MFSMCEHHL
Sbjct: 128 EMVIVKDIDMFSMCEHHL 145
>UniRef50_Q19980 Cluster: GTP cyclohydrolase I; n=89; cellular
organisms|Rep: GTP cyclohydrolase I - Caenorhabditis
elegans
Length = 223
Score = 107 bits (256), Expect = 3e-22
Identities = 48/78 (61%), Positives = 59/78 (75%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD 600
L M N+Y+ ++ +GED R GLL TPERAAKAM+ FTKGYD L+E+LN A+FDE D
Sbjct: 40 LKSMCNAYQSIIQHVGEDINRQGLLKTPERAAKAMMAFTKGYDDQLDELLNEAVFDEDHD 99
Query: 601 XMVVVXDIXMFSMCEHHL 654
MV+V DI MFS+CEHHL
Sbjct: 100 EMVIVKDIEMFSLCEHHL 117
>UniRef50_Q8YLL1 Cluster: GTP cyclohydrolase I 1; n=29;
Bacteria|Rep: GTP cyclohydrolase I 1 - Anabaena sp.
(strain PCC 7120)
Length = 235
Score = 102 bits (244), Expect = 9e-21
Identities = 46/83 (55%), Positives = 59/83 (71%)
Frame = +1
Query: 406 PGXALLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIF 585
P + M + R +L G+GEDPER GLL TP+R A+AM F T GY+QSLEE+LN A+F
Sbjct: 43 PSEEDMESMMGAVRSILVGVGEDPEREGLLKTPKRVAEAMRFLTSGYNQSLEELLNGAVF 102
Query: 586 DEXTDXMVVVXDIXMFSMCEHHL 654
DE + MV+V DI FS+CEHH+
Sbjct: 103 DEGHNEMVLVRDINFFSLCEHHM 125
>UniRef50_Q4SEZ7 Cluster: Chromosome 1 SCAF14609, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
SCAF14609, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 263
Score = 99.5 bits (237), Expect = 6e-20
Identities = 47/82 (57%), Positives = 59/82 (71%)
Frame = +1
Query: 409 GXALLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFD 588
G + M SY+ +LT LGED R GL TP RAAKAM F TKGY++S++E+LN+AIFD
Sbjct: 32 GADRVSQMEKSYKDILTELGEDATREGLQRTPLRAAKAMQFLTKGYNESVKEILNDAIFD 91
Query: 589 EXTDXMVVVXDIXMFSMCEHHL 654
E +V+V DI MFS+CEHHL
Sbjct: 92 ENHQEVVIVKDIEMFSLCEHHL 113
>UniRef50_A6QSY1 Cluster: GTP cyclohydrolase I; n=3; cellular
organisms|Rep: GTP cyclohydrolase I - Ajellomyces
capsulatus NAm1
Length = 390
Score = 99.5 bits (237), Expect = 6e-20
Identities = 41/75 (54%), Positives = 60/75 (80%)
Frame = +1
Query: 430 MANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMV 609
+AN+ R +L +GEDPER GLL TPER AKA+++FTKGY++++ +++N A+F E D +V
Sbjct: 210 LANAVRTVLECIGEDPEREGLLGTPERYAKALMYFTKGYEENVRDLVNGAVFHEDHDELV 269
Query: 610 VVXDIXMFSMCEHHL 654
+V DI +FS+CEHHL
Sbjct: 270 IVKDIEIFSLCEHHL 284
>UniRef50_P51599 Cluster: GTP cyclohydrolase I; n=14;
Ascomycota|Rep: GTP cyclohydrolase I - Neurospora crassa
Length = 313
Score = 99.5 bits (237), Expect = 6e-20
Identities = 45/78 (57%), Positives = 57/78 (73%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD 600
L M + R LL +GEDP+R GLL TPER AKAMLF TKGY +++ +++N AIF E +
Sbjct: 129 LDKMKGAVRTLLECIGEDPDREGLLATPERYAKAMLFLTKGYQENVRDIVNGAIFQEGHN 188
Query: 601 XMVVVXDIXMFSMCEHHL 654
MV+V DI +FSMCEHHL
Sbjct: 189 EMVIVKDIEVFSMCEHHL 206
>UniRef50_Q94465 Cluster: GTP cyclohydrolase I; n=2; Dictyostelium
discoideum|Rep: GTP cyclohydrolase I - Dictyostelium
discoideum (Slime mold)
Length = 232
Score = 99.5 bits (237), Expect = 6e-20
Identities = 45/79 (56%), Positives = 61/79 (77%)
Frame = +1
Query: 418 LLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT 597
+L M +S + LL+ LGEDP+R GLL TP R +KA+LFFT+GY+QS++EV+ AIF+E
Sbjct: 47 VLNTMQSSVKTLLSSLGEDPDREGLLKTPLRMSKALLFFTQGYEQSVDEVIGEAIFNENH 106
Query: 598 DXMVVVXDIXMFSMCEHHL 654
MVVV DI +FS+CEHH+
Sbjct: 107 HEMVVVRDIDIFSLCEHHM 125
>UniRef50_Q8KEA8 Cluster: GTP cyclohydrolase I; n=46; Bacteria|Rep:
GTP cyclohydrolase I - Chlorobium tepidum
Length = 224
Score = 94.7 bits (225), Expect = 2e-18
Identities = 43/79 (54%), Positives = 56/79 (70%)
Frame = +1
Query: 418 LLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT 597
+L M ++ LL G+GEDPER GLL TPER AK++ F TKGY Q E++L A+F E
Sbjct: 40 VLGSMTDAVYSLLKGVGEDPEREGLLLTPERVAKSLRFLTKGYRQDPEQLLKKAVFTESY 99
Query: 598 DXMVVVXDIXMFSMCEHHL 654
D MV+V DI ++SMCEHH+
Sbjct: 100 DEMVLVKDIDIYSMCEHHM 118
>UniRef50_Q2GYY2 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 233
Score = 93.1 bits (221), Expect = 5e-18
Identities = 40/78 (51%), Positives = 58/78 (74%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD 600
L + ++ R +L +GE+P+R G+L TPER AKAM+F T+GY Q++ E++NNAIF E
Sbjct: 87 LGKLGDAVRTMLECIGENPDRPGVLNTPERYAKAMMFLTQGYGQNIHEIVNNAIFHEGHH 146
Query: 601 XMVVVXDIXMFSMCEHHL 654
MV+V DI +FS+CEHH+
Sbjct: 147 EMVIVKDIDIFSICEHHM 164
>UniRef50_A6RNT4 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1504
Score = 87.4 bits (207), Expect = 3e-16
Identities = 39/76 (51%), Positives = 54/76 (71%)
Frame = +1
Query: 427 DMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXM 606
++A + R LL +GED R GL TPER AKA+ FFT+GY + E++N AIF+E T+ M
Sbjct: 98 EIAATIRTLLCQIGEDTNRDGLKKTPERYAKALQFFTQGYKEKSNELINGAIFNEDTEDM 157
Query: 607 VVVXDIXMFSMCEHHL 654
V+V I +FS+CEHH+
Sbjct: 158 VIVSGIDVFSLCEHHM 173
>UniRef50_Q6F9M5 Cluster: GTP cyclohydrolase I; n=3; cellular
organisms|Rep: GTP cyclohydrolase I - Acinetobacter sp.
(strain ADP1)
Length = 197
Score = 86.6 bits (205), Expect = 5e-16
Identities = 42/78 (53%), Positives = 50/78 (64%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD 600
L M SY +LT +GED R GL TP RAAKA F T GY +SLEEV NNA+F
Sbjct: 13 LMSMQQSYANILTAVGEDLNRPGLKDTPIRAAKAFSFLTSGYGKSLEEVTNNAVFPSDNH 72
Query: 601 XMVVVXDIXMFSMCEHHL 654
MV+V +I +S+CEHHL
Sbjct: 73 EMVLVKNIEFYSLCEHHL 90
>UniRef50_A5WE14 Cluster: GTP cyclohydrolase I; n=4;
Pseudomonadales|Rep: GTP cyclohydrolase I -
Psychrobacter sp. PRwf-1
Length = 201
Score = 79.8 bits (188), Expect = 5e-14
Identities = 37/71 (52%), Positives = 46/71 (64%)
Frame = +1
Query: 442 YRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXD 621
Y L+ GED R GLL TP RAAKA + T+GY QSL EV NNA+F +V+V +
Sbjct: 23 YAKLIASTGEDLNRPGLLDTPTRAAKAFGYLTQGYHQSLTEVTNNAVFPTDNSELVLVHN 82
Query: 622 IXMFSMCEHHL 654
I +S+CEHHL
Sbjct: 83 IEFYSLCEHHL 93
>UniRef50_Q9RYB4 Cluster: GTP cyclohydrolase I; n=5; Bacteria|Rep:
GTP cyclohydrolase I - Deinococcus radiodurans
Length = 216
Score = 78.2 bits (184), Expect = 2e-13
Identities = 37/82 (45%), Positives = 50/82 (60%), Gaps = 4/82 (4%)
Frame = +1
Query: 421 LPDMANSYRLL----LTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFD 588
LPD N+ L L +GEDP+R GL TP+R AKA + T+GY Q+L +V+ +F
Sbjct: 25 LPDNPNNLEPLTREWLAAIGEDPDREGLQRTPQRVAKAWAYMTEGYGQTLAQVVGEGVFA 84
Query: 589 EXTDXMVVVXDIXMFSMCEHHL 654
MV+V DI +SMCEHH+
Sbjct: 85 AEGSEMVIVKDIEFYSMCEHHM 106
>UniRef50_A5UR68 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep:
GTP cyclohydrolase I - Roseiflexus sp. RS-1
Length = 226
Score = 71.3 bits (167), Expect = 2e-11
Identities = 33/77 (42%), Positives = 48/77 (62%)
Frame = +1
Query: 424 PDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDX 603
P + ++ R++L +GE+PER GLL TP R AK T GY + ++N+AIF D
Sbjct: 44 PAIEDAVRVILKQIGENPEREGLLKTPSRVAKMYAELTAGYHIDPDALINDAIFSVSYDE 103
Query: 604 MVVVXDIXMFSMCEHHL 654
MV+V +I S+CEHH+
Sbjct: 104 MVLVKNIEFASLCEHHM 120
>UniRef50_Q3WEZ6 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep:
GTP cyclohydrolase I - Frankia sp. EAN1pec
Length = 257
Score = 70.9 bits (166), Expect = 2e-11
Identities = 36/75 (48%), Positives = 47/75 (62%)
Frame = +1
Query: 430 MANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMV 609
+A + R LL G+GEDP+R GL TP+R A+A +G + EVL +FDE D MV
Sbjct: 76 VARAVRELLIGIGEDPDREGLRKTPDRVARAYQEAVEGLGRDPAEVL-TTVFDEGHDEMV 134
Query: 610 VVXDIXMFSMCEHHL 654
+V DI S+CEHHL
Sbjct: 135 LVRDIDFSSLCEHHL 149
>UniRef50_Q8G0L4 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Rep:
GTP cyclohydrolase I - Brucella suis
Length = 213
Score = 69.3 bits (162), Expect = 8e-11
Identities = 38/72 (52%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT--DXMVVVX 618
R LL GEDP+R GLL TP+R AKA GY +S EEVL F+E D MV+V
Sbjct: 38 RTLLLWAGEDPDREGLLETPKRVAKAYQELFGGYSESPEEVLGTT-FEEVAGYDDMVLVK 96
Query: 619 DIXMFSMCEHHL 654
DI FS CEHH+
Sbjct: 97 DISFFSHCEHHM 108
>UniRef50_Q8G3S1 Cluster: GTP cyclohydrolase I; n=4;
Bifidobacterium|Rep: GTP cyclohydrolase I -
Bifidobacterium longum
Length = 199
Score = 66.5 bits (155), Expect = 5e-10
Identities = 33/70 (47%), Positives = 43/70 (61%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDI 624
RL L +GEDPER GL+ TP+R A+A G S + L FD TD +V+V DI
Sbjct: 25 RLFLKSIGEDPEREGLVETPDRIARACRELFTGLQASPADALEKH-FDVDTDELVLVKDI 83
Query: 625 XMFSMCEHHL 654
++S+CEHHL
Sbjct: 84 ELYSVCEHHL 93
>UniRef50_A7QSC6 Cluster: Chromosome chr3 scaffold_158, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr3 scaffold_158, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 214
Score = 66.1 bits (154), Expect = 7e-10
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDI 624
++LL GLGED R G+ TP R AKA+ T+GY Q ++++ A+F E +V+V D+
Sbjct: 35 KVLLQGLGEDINREGIRKTPARVAKALCEGTRGYRQKAKDIVQGALFPEAVGGLVIVRDL 94
Query: 625 XMFSMCE 645
+FS CE
Sbjct: 95 DLFSYCE 101
>UniRef50_A5EFZ1 Cluster: GTP cyclohydrolase I; n=6;
Proteobacteria|Rep: GTP cyclohydrolase I -
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 206
Score = 64.9 bits (151), Expect = 2e-09
Identities = 34/78 (43%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Frame = +1
Query: 427 DMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT--D 600
D+ ++ R +LT +GEDP R GL TP R A+A + GYDQ+ EE L F+E D
Sbjct: 21 DVEDAIRTILTWIGEDPSREGLSETPARVARAYKSYFAGYDQNPEEYLRKT-FEETAGYD 79
Query: 601 XMVVVXDIXMFSMCEHHL 654
MV++ +I S CEHH+
Sbjct: 80 EMVLLRNIPFQSHCEHHM 97
>UniRef50_Q0CVT9 Cluster: GTP cyclohydrolase I; n=1; Aspergillus
terreus NIH2624|Rep: GTP cyclohydrolase I - Aspergillus
terreus (strain NIH 2624)
Length = 216
Score = 64.1 bits (149), Expect = 3e-09
Identities = 30/62 (48%), Positives = 42/62 (67%)
Frame = +1
Query: 430 MANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMV 609
+A + R +L +GEDP R GL TPER AKAML+FTKGY +++ + N AIF E ++
Sbjct: 56 IAKAVRTILECVGEDPGREGLRATPERYAKAMLYFTKGYSENIFDRANGAIFHEDYKGLI 115
Query: 610 VV 615
V+
Sbjct: 116 VM 117
>UniRef50_UPI0000F1DBDC Cluster: PREDICTED: similar to GTP
cyclohydrolase I (form A; N-terminus), partial; n=1;
Danio rerio|Rep: PREDICTED: similar to GTP
cyclohydrolase I (form A; N-terminus), partial - Danio
rerio
Length = 115
Score = 62.5 bits (145), Expect = 9e-09
Identities = 28/46 (60%), Positives = 34/46 (73%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSL 558
LP +A +Y +L GLGEDP+R GLL TP RAA AM FFTKGY + +
Sbjct: 69 LPSIAAAYTTILRGLGEDPQRQGLLKTPWRAATAMQFFTKGYQEKI 114
>UniRef50_Q5NN57 Cluster: GTP cyclohydrolase I; n=4;
Sphingomonadales|Rep: GTP cyclohydrolase I - Zymomonas
mobilis
Length = 220
Score = 62.1 bits (144), Expect = 1e-08
Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Frame = +1
Query: 400 RPPGXALLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNA 579
RP + ++ + R L+ G+DP+R GL+ TP+R AKA ++ +GY + E L
Sbjct: 30 RPDQVNVPEEIQEAIRSLIRWAGDDPDREGLIDTPKRVAKAWKYYCRGYREDPENHL-KT 88
Query: 580 IFDE--XTDXMVVVXDIXMFSMCEHHL 654
+F+E D +V++ DI +S CEHH+
Sbjct: 89 VFEEVGGYDDIVLLKDIPFYSHCEHHM 115
>UniRef50_O69531 Cluster: GTP cyclohydrolase I; n=98; Bacteria|Rep:
GTP cyclohydrolase I - Mycobacterium leprae
Length = 205
Score = 62.1 bits (144), Expect = 1e-08
Identities = 32/70 (45%), Positives = 42/70 (60%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDI 624
R LL +GEDP+R GL TP R A+A G + VL N +FDE + +V+V +I
Sbjct: 29 RELLYAIGEDPDREGLADTPARVARACRELFSGLYTDPQTVL-NTMFDEEHNELVIVKEI 87
Query: 625 XMFSMCEHHL 654
M+S CEHHL
Sbjct: 88 PMYSTCEHHL 97
>UniRef50_A6SZ52 Cluster: GTP cyclohydrolase I; n=2; root|Rep: GTP
cyclohydrolase I - Janthinobacterium sp. (strain
Marseille) (Minibacterium massiliensis)
Length = 198
Score = 61.7 bits (143), Expect = 2e-08
Identities = 33/74 (44%), Positives = 46/74 (62%), Gaps = 3/74 (4%)
Frame = +1
Query: 442 YRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFD---EXTDXMVV 612
+R LLT LGE+ +R GL TP+R KA +T GYDQ E+L +F+ E + ++V
Sbjct: 20 WRRLLTHLGENADRQGLRETPQRVEKAWKHWTSGYDQDPAEILK--VFEDGAEQYNELIV 77
Query: 613 VXDIXMFSMCEHHL 654
V I ++S CEHHL
Sbjct: 78 VRGIPVYSHCEHHL 91
>UniRef50_Q2Q448 Cluster: GTP cyclohydrolase I; n=1; Toxoplasma
gondii|Rep: GTP cyclohydrolase I - Toxoplasma gondii
Length = 262
Score = 60.1 bits (139), Expect = 5e-08
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 11/99 (11%)
Frame = +1
Query: 391 TTDRPPGXALLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVL 570
+TD+ G + R++L +GED RAGL TP+R A AM FF++GY ++V+
Sbjct: 53 STDQGLGEDKKNAIEEGVRMILRAMGEDVTRAGLRETPKRVAAAMEFFSRGYRADPKDVI 112
Query: 571 NNAIFD-----------EXTDXMVVVXDIXMFSMCEHHL 654
NA+F MV V I + S+CEHHL
Sbjct: 113 RNALFSVEEGHEDGQYLAGKQGMVTVGRIDISSLCEHHL 151
>UniRef50_Q7VFG4 Cluster: GTP cyclohydrolase I; n=6;
Helicobacter|Rep: GTP cyclohydrolase I - Helicobacter
hepaticus
Length = 206
Score = 59.3 bits (137), Expect = 8e-08
Identities = 27/71 (38%), Positives = 40/71 (56%)
Frame = +1
Query: 442 YRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXD 621
+ L +GE+P R GLL TP+R A A GY +S ++ L + D D M+V+
Sbjct: 32 FESLCQNVGENPTREGLLHTPKRIASAFSDMLNGYAKSPKQALGSVFEDGVCDEMIVLKK 91
Query: 622 IXMFSMCEHHL 654
+ +S+CEHHL
Sbjct: 92 LHFYSICEHHL 102
>UniRef50_Q92QB4 Cluster: GTP cyclohydrolase I; n=49;
Proteobacteria|Rep: GTP cyclohydrolase I - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 204
Score = 58.4 bits (135), Expect = 1e-07
Identities = 33/72 (45%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT--DXMVVVX 618
R+LL GEDP R GL TP R AKA GYD E+VL F+E + D +V+
Sbjct: 27 RVLLRWAGEDPAREGLKDTPSRVAKAYREIFGGYDLVAEDVLGRT-FEEVSGYDDIVLEK 85
Query: 619 DIXMFSMCEHHL 654
DI +S CEHH+
Sbjct: 86 DIPFYSHCEHHM 97
>UniRef50_A4QTK3 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 216
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/62 (41%), Positives = 42/62 (67%)
Frame = +1
Query: 430 MANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMV 609
+A + R ++ +GEDP R GL TP R A+A+ FFT+GY +++ EV N+AIF + +V
Sbjct: 53 IAAAAREIICAVGEDPAREGLAETPNRYAEALQFFTQGYSKNIHEVSNDAIFSIDSRELV 112
Query: 610 VV 615
++
Sbjct: 113 IM 114
>UniRef50_A2BL58 Cluster: GTP cyclohydrolase I; n=2;
Thermoprotei|Rep: GTP cyclohydrolase I - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 193
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/70 (45%), Positives = 40/70 (57%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDI 624
R++L +GEDPER GL TP R A +GYD + E F E TD +VVV I
Sbjct: 13 RMILEAIGEDPEREGLRETPRRVADMFEELLEGYDFTEEYTW----FTEATD-LVVVSGI 67
Query: 625 XMFSMCEHHL 654
+S+CEHHL
Sbjct: 68 RFYSLCEHHL 77
>UniRef50_P0C0C1 Cluster: GTP cyclohydrolase I; n=23; Bacteria|Rep:
GTP cyclohydrolase I - Streptococcus pyogenes
Length = 194
Score = 57.2 bits (132), Expect = 3e-07
Identities = 28/66 (42%), Positives = 38/66 (57%)
Frame = +1
Query: 454 LTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDIXMF 633
L +GE+P R GLL TP+R AK G + +E A+F E + +V+V DI +
Sbjct: 22 LEAIGENPNREGLLDTPKRVAKMYAEMFAGLKKDPKEEFT-AVFTEHHEDVVIVKDISFY 80
Query: 634 SMCEHH 651
SMCEHH
Sbjct: 81 SMCEHH 86
>UniRef50_Q68WZ4 Cluster: GTP cyclohydrolase 1; n=25; Bacteria|Rep:
GTP cyclohydrolase 1 - Rickettsia typhi
Length = 190
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT-DXMVVVXD 621
R LL +GEDP R GLL TP+R + + GY + ++E+LN +D ++ +
Sbjct: 14 RTLLRFIGEDPTREGLLKTPDRVINSYMEIFSGYGKDVQEILNTKFYDTYNFQDLISLEG 73
Query: 622 IXMFSMCEHHL 654
I S CEHH+
Sbjct: 74 IKFTSFCEHHI 84
>UniRef50_Q6NF93 Cluster: GTP cyclohydrolase I; n=8; Bacteria|Rep:
GTP cyclohydrolase I - Corynebacterium diphtheriae
Length = 190
Score = 56.4 bits (130), Expect = 6e-07
Identities = 32/70 (45%), Positives = 38/70 (54%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDI 624
R LL +GEDP+R GL TP R AKA G EVL F E +V+V DI
Sbjct: 15 RELLIAVGEDPDREGLQETPARVAKAYAEMFAGLHTDPTEVLAKT-FSEDHREVVLVRDI 73
Query: 625 XMFSMCEHHL 654
++S CEHHL
Sbjct: 74 PIYSTCEHHL 83
>UniRef50_A4G565 Cluster: GTP cyclohydrolase I; n=2;
Betaproteobacteria|Rep: GTP cyclohydrolase I -
Herminiimonas arsenicoxydans
Length = 215
Score = 56.0 bits (129), Expect = 7e-07
Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Frame = +1
Query: 436 NSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD---XM 606
+ +R LL LGE+P R GL TP+R KA +T GY Q E+L +F + + +
Sbjct: 35 HDWRRLLIHLGENPNRQGLQETPKRVQKAWQQWTAGYAQDPAEILK--VFSDGAEQYKEL 92
Query: 607 VVVXDIXMFSMCEHHL 654
++V I ++S CEHHL
Sbjct: 93 IIVRGIPVYSHCEHHL 108
>UniRef50_Q97D54 Cluster: GTP cyclohydrolase I; n=7;
Clostridium|Rep: GTP cyclohydrolase I - Clostridium
acetobutylicum
Length = 195
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/77 (41%), Positives = 45/77 (58%), Gaps = 7/77 (9%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEV--LNNAIFDE-----XTDX 603
R +L LG+DP+R GL TP+R AK KG + S +++ + N F+E D
Sbjct: 13 RGILIALGDDPDREGLKETPKRVAKMYEEVFKGMEYSNDDIAEMFNKTFEEDLKESEEDN 72
Query: 604 MVVVXDIXMFSMCEHHL 654
+V+V DI +FS CEHHL
Sbjct: 73 IVLVKDIEIFSHCEHHL 89
>UniRef50_UPI0000DADB56 Cluster: hypothetical protein
RcanM_01000666; n=1; Rickettsia canadensis str.
McKiel|Rep: hypothetical protein RcanM_01000666 -
Rickettsia canadensis str. McKiel
Length = 222
Score = 54.4 bits (125), Expect = 2e-06
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT-DXMVVVXD 621
R LL +GEDP R GLL TP+R + + GY++ + E+L+ +D + +
Sbjct: 46 RTLLKFIGEDPNREGLLKTPDRVINSYMEIFSGYEKDVAEILSTKFYDTCNFQDFISLDG 105
Query: 622 IXMFSMCEHHL 654
I S CEHH+
Sbjct: 106 IRFTSFCEHHM 116
>UniRef50_Q82Z12 Cluster: GTP cyclohydrolase I; n=1; Enterococcus
faecalis|Rep: GTP cyclohydrolase I - Enterococcus
faecalis (Streptococcus faecalis)
Length = 186
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/69 (42%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
Frame = +1
Query: 451 LLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD-XMVVVXDIX 627
+L +GED +RAGL+ TP+R AK G + E + +FD + MV+V DI
Sbjct: 16 ILEAVGEDTQRAGLIDTPKRVAKMYAEVFSGLTE--PEFDDYKLFDSLNEGEMVLVKDIA 73
Query: 628 MFSMCEHHL 654
+SMCEHHL
Sbjct: 74 FYSMCEHHL 82
>UniRef50_Q89IW2 Cluster: GTP cyclohydrolase I; n=13; Bacteria|Rep:
GTP cyclohydrolase I - Bradyrhizobium japonicum
Length = 229
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT--DXMVVVX 618
+ LL +GE+ ER GLL TP R +A +GY Q EVL+ F E D V+V
Sbjct: 52 KTLLAYIGENTEREGLLDTPRRVVEAFDELYQGYHQCPAEVLDRT-FGETAGYDDFVLVR 110
Query: 619 DIXMFSMCEHHL 654
DI S CEHH+
Sbjct: 111 DIEFTSQCEHHM 122
>UniRef50_A2U8J6 Cluster: GTP cyclohydrolase I; n=2; Bacillus|Rep:
GTP cyclohydrolase I - Bacillus coagulans 36D1
Length = 215
Score = 53.2 bits (122), Expect = 5e-06
Identities = 28/70 (40%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAI-FDEXTDXMVVVXD 621
R L+ G+DP+R GL TP R KA L +T+GY + + L D +V+V D
Sbjct: 41 RSLIDLCGDDPDRDGLQETPYRVLKAFLEYTEGYREDPKLHLAKTFDVDHDHKELVLVKD 100
Query: 622 IXMFSMCEHH 651
I +S+CEHH
Sbjct: 101 IEFYSICEHH 110
>UniRef50_Q971G9 Cluster: GTP cyclohydrolase I; n=4;
Sulfolobaceae|Rep: GTP cyclohydrolase I - Sulfolobus
tokodaii
Length = 215
Score = 52.8 bits (121), Expect = 7e-06
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 4/83 (4%)
Frame = +1
Query: 418 LLPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEV----LNNAIF 585
++ ++A R +L LGE+P+R GL TP R A+A+L T G ++ L+
Sbjct: 18 MVEEIAKRIREILEILGENPDREGLRETPLRVARALLEMTSGLRTPQPQIKTFNLSEDGI 77
Query: 586 DEXTDXMVVVXDIXMFSMCEHHL 654
E D +++V +I S+CEHHL
Sbjct: 78 SEVEDQIILVKNIGFSSLCEHHL 100
>UniRef50_Q01A10 Cluster: GTP cyclohydrolase I; n=2;
Ostreococcus|Rep: GTP cyclohydrolase I - Ostreococcus
tauri
Length = 504
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/55 (43%), Positives = 33/55 (60%)
Frame = +1
Query: 427 DMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 591
D++ R +L +GED ER GL+ TP R AKA+ F +GYD L A+F+E
Sbjct: 56 DVSRCVREMLRAMGEDVEREGLMDTPARVAKALAFAMRGYDACPTAALGTALFNE 110
>UniRef50_Q1IAJ6 Cluster: Putative GTP cyclohydrolase I; n=1;
Pseudomonas entomophila L48|Rep: Putative GTP
cyclohydrolase I - Pseudomonas entomophila (strain L48)
Length = 202
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/70 (42%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +1
Query: 451 LLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT--DXMVVVXDI 624
+L LGED R GL TPER K+M+ T GY Q VL F+E ++++ +I
Sbjct: 19 ILEYLGEDTNRQGLHETPERFLKSMVAQTVGYSQDPYRVLEK-FFEEVAGYKNLIMLQNI 77
Query: 625 XMFSMCEHHL 654
SMCEHHL
Sbjct: 78 HFESMCEHHL 87
>UniRef50_Q5HBC9 Cluster: GTP cyclohydrolase I; n=4; canis
group|Rep: GTP cyclohydrolase I - Ehrlichia ruminantium
(strain Welgevonden)
Length = 190
Score = 51.2 bits (117), Expect = 2e-05
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +1
Query: 427 DMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIF-DEXTDX 603
++ ++ LL+ +G+D +R GL+ TP R A F GY Q + V+ ++ +E D
Sbjct: 11 EVEDAISLLIRWIGDDVDRPGLIGTPRRMLNAYKKFFIGY-QDISLVIGGSVLPNEGYDS 69
Query: 604 MVVVXDIXMFSMCEHHL 654
M+ DI S CEHH+
Sbjct: 70 MITFKDIGFVSYCEHHI 86
>UniRef50_Q88ST4 Cluster: GTP cyclohydrolase I; n=11;
Lactobacillales|Rep: GTP cyclohydrolase I -
Lactobacillus plantarum
Length = 189
Score = 51.2 bits (117), Expect = 2e-05
Identities = 31/76 (40%), Positives = 45/76 (59%), Gaps = 3/76 (3%)
Frame = +1
Query: 436 NSYRLLLTGLGEDPERAGLLXTPERAAK--AMLFFTKGYDQSLEEVLNNAIFD-EXTDXM 606
++ R +L+ +GEDP+R GL+ TP R A+ A +F TK + N +F E M
Sbjct: 12 HAVREILSAVGEDPDRPGLVETPARVARMYAEVFATK----TAAPFDNYKLFKVEHPTEM 67
Query: 607 VVVXDIXMFSMCEHHL 654
V++ DI +SMCEHHL
Sbjct: 68 VLLKDIPFYSMCEHHL 83
>UniRef50_Q9PC02 Cluster: GTP cyclohydrolase I; n=16; Bacteria|Rep:
GTP cyclohydrolase I - Xylella fastidiosa
Length = 203
Score = 50.0 bits (114), Expect = 5e-05
Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXT--DXMVVVX 618
R LL GEDP R GLL TP R +A + GY + + L F+E + D ++V+
Sbjct: 21 RTLLRWAGEDPTREGLLDTPRRVVEAYGDWFSGYREDPHDYLQRT-FEEISGYDELIVLR 79
Query: 619 DIXMFSMCEHHL 654
+I S CEHH+
Sbjct: 80 NITYESHCEHHM 91
>UniRef50_A0RYT5 Cluster: GTP cyclohydrolase I; n=2;
Thermoprotei|Rep: GTP cyclohydrolase I - Cenarchaeum
symbiosum
Length = 189
Score = 49.6 bits (113), Expect = 6e-05
Identities = 29/70 (41%), Positives = 37/70 (52%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDI 624
R L+ LGEDP R GL TP R A+ GY+ E + F E +D VV DI
Sbjct: 11 RELIIELGEDPTREGLRETPARMARMYGEIFGGYESDAELSVQ---FSEDSDA-VVARDI 66
Query: 625 XMFSMCEHHL 654
+S+CEHH+
Sbjct: 67 GFYSVCEHHM 76
>UniRef50_Q2GK14 Cluster: GTP cyclohydrolase I; n=2; Anaplasma
phagocytophilum HZ|Rep: GTP cyclohydrolase I - Anaplasma
phagocytophilum (strain HZ)
Length = 202
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTD 600
+ + + R+++ +G+DP R GLL TP R GY L + +D +
Sbjct: 14 IEEAEEAVRVIIRWMGDDPNREGLLKTPRRVLDYYKKSCSGYAPELLSHYSILPYDGSSS 73
Query: 601 XMVVVXDIXMFSMCEHHL 654
MV+V +I S CEHHL
Sbjct: 74 EMVLVKNIGFSSNCEHHL 91
>UniRef50_Q8S3C2 Cluster: GTP cyclohydrolase I; n=7; core
eudicotyledons|Rep: GTP cyclohydrolase I - Arabidopsis
thaliana (Mouse-ear cress)
Length = 466
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 11/81 (13%)
Frame = +1
Query: 436 NSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEX------- 594
++ +LLL GL ED R G+ TP R AKA+ T+GY Q +++ + +A+F E
Sbjct: 37 DAVKLLLQGLHEDVNREGIKKTPFRVAKALREGTRGYKQKVKDYVQSALFPEAGLDEGVG 96
Query: 595 ----TDXMVVVXDIXMFSMCE 645
+VVV D+ +S CE
Sbjct: 97 QAGGVGGLVVVRDLDHYSYCE 117
Score = 41.5 bits (93), Expect = 0.017
Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Frame = +1
Query: 424 PDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTK-GYDQSLEEVLNNAIFDEXTD 600
P+M ++ +L LGEDP R L+ TP R K ML F + + L + E +
Sbjct: 268 PEMVSAVVSILKSLGEDPLRKELIATPTRFLKWMLNFQRTNLEMKLNSFNPAKVNGEVKE 327
Query: 601 XMV-VVXDIXMFSMCEHHL 654
+ ++ +SMCEHHL
Sbjct: 328 KRLHCELNMPFWSMCEHHL 346
>UniRef50_Q5V5Y0 Cluster: GTP cyclohydrolase I; n=1; Haloarcula
marismortui|Rep: GTP cyclohydrolase I - Haloarcula
marismortui (Halobacterium marismortui)
Length = 210
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/71 (38%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAML-FFTKGYDQSLEEVLNNAIFDEXTDXMVVVXD 621
RLLL G DP+ AGL T R M T+G + ++ FD TD ++V
Sbjct: 32 RLLLEAAGRDPDSAGLSDTWSRRVPDMFETLTEGARSESKPIMRT--FDAETDGLIVKTG 89
Query: 622 IXMFSMCEHHL 654
I + SMCEHH+
Sbjct: 90 IPLHSMCEHHM 100
>UniRef50_Q8ZWW5 Cluster: GTP cyclohydrolase I; n=4;
Pyrobaculum|Rep: GTP cyclohydrolase I - Pyrobaculum
aerophilum
Length = 187
Score = 47.2 bits (107), Expect = 3e-04
Identities = 27/68 (39%), Positives = 38/68 (55%)
Frame = +1
Query: 451 LLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDIXM 630
LL LGED + G+L TP+R KAM T+G + EV+ + + VV+ +I
Sbjct: 18 LLEYLGEDLTKPGVLNTPKRFVKAMEELTRGLREPPPEVVFFPLEYDVELGPVVIENIGA 77
Query: 631 FSMCEHHL 654
S+CEHHL
Sbjct: 78 VSLCEHHL 85
>UniRef50_Q8T649 Cluster: GTP cyclohydrolase I; n=3; Plasmodium
yoelii|Rep: GTP cyclohydrolase I - Plasmodium yoelii
yoelii
Length = 315
Score = 46.4 bits (105), Expect = 6e-04
Identities = 20/57 (35%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Frame = +1
Query: 490 LLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE--XTDXMVVVXDIXMFSMCEHHL 654
L T R AKA L+ T+GY S++ V+ +I+ + ++ + DI ++S+C+HHL
Sbjct: 142 LKRTNNRFAKAFLYLTEGYKMSVKNVIKKSIYKRKYKNNTLIKIKDIHVYSLCKHHL 198
>UniRef50_UPI00015BB290 Cluster: GTP cyclohydrolase; n=1; Ignicoccus
hospitalis KIN4/I|Rep: GTP cyclohydrolase - Ignicoccus
hospitalis KIN4/I
Length = 186
Score = 46.0 bits (104), Expect = 8e-04
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Frame = +1
Query: 454 LTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLN-NAIFDEXTDXMVVVXDIXM 630
L +GEDP R GL TPER +A+ KG + E+ + + ++VV ++
Sbjct: 14 LEEMGEDPSRPGLSETPERYVRALRELFKGLETPKPELKTFKTEYLLGENDLIVVKNVSF 73
Query: 631 FSMCEHHL 654
S+CEHHL
Sbjct: 74 SSLCEHHL 81
>UniRef50_Q1FI35 Cluster: GTP cyclohydrolase I; n=1; Clostridium
phytofermentans ISDg|Rep: GTP cyclohydrolase I -
Clostridium phytofermentans ISDg
Length = 194
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Frame = +1
Query: 451 LLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLN--NAIFDE-----XTDXMV 609
+L LGEDP R GL+ TP+R A G + ++++ N F+E + +V
Sbjct: 15 ILIALGEDPLREGLIDTPKRVANMYEEVFLGIQYTNDDIVTMFNKCFEEDQNTFLANGIV 74
Query: 610 VVXDIXMFSMCEHHL 654
+ DI FS CEHH+
Sbjct: 75 WIKDIECFSFCEHHM 89
>UniRef50_Q2JC68 Cluster: GTP cyclohydrolase I; n=1; Frankia sp.
CcI3|Rep: GTP cyclohydrolase I - Frankia sp. (strain
CcI3)
Length = 192
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +1
Query: 445 RLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVV-VXD 621
R LL +GEDP R GL TP R A+ F G+D E F++ +V V D
Sbjct: 28 RQLLVEIGEDPGRDGLRETPARYARWWREFV-GFDPGNTETA----FEQVNHGQLVQVND 82
Query: 622 IXMFSMCEHHL 654
I ++S+CEHHL
Sbjct: 83 IRVWSLCEHHL 93
>UniRef50_Q6SIF0 Cluster: GTP cyclohydrolase I; n=1; Plasmodium
knowlesi|Rep: GTP cyclohydrolase I - Plasmodium knowlesi
Length = 451
Score = 43.6 bits (98), Expect = 0.004
Identities = 21/80 (26%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Frame = +1
Query: 421 LPDMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEX-- 594
+ D++ S + +L + P + L T R + L+ TKGY S+E+V+ +++
Sbjct: 253 IADISRSIKKILRS-SKVPPKDILKKTGRRFSDTFLYLTKGYHMSVEKVIKKSLYKRNYK 311
Query: 595 TDXMVVVXDIXMFSMCEHHL 654
+ ++ + I ++S+C+HHL
Sbjct: 312 NNSVIKISGIHIYSLCKHHL 331
>UniRef50_O97071 Cluster: GTP cyclohydrolase I; n=6; Plasmodium|Rep:
GTP cyclohydrolase I - Plasmodium falciparum
Length = 389
Score = 40.3 bits (90), Expect = 0.040
Identities = 16/57 (28%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Frame = +1
Query: 490 LLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEX--TDXMVVVXDIXMFSMCEHHL 654
L T R A+ L+ T GY+ +E+++ +++ + ++ V I ++S+C+HHL
Sbjct: 225 LKRTNRRYAETFLYLTNGYNLDIEQIIKRSLYKRMYKNNSIIKVTGIHIYSLCKHHL 281
>UniRef50_Q54768 Cluster: Putative uncharacterized protein; n=1;
Synechococcus elongatus PCC 7942|Rep: Putative
uncharacterized protein - Synechococcus sp. (strain PCC
7942) (Anacystis nidulans R2)
Length = 227
Score = 39.5 bits (88), Expect = 0.069
Identities = 18/57 (31%), Positives = 28/57 (49%)
Frame = -3
Query: 651 MMFAH*KHXDIXNDHHXVRVFIEDGVVQNLFQALVVSFREEEHSFGGTFGRXQEPCP 481
++F + D+ + HH V F+EDG V + Q L V+ ++ F QEP P
Sbjct: 119 VVFTKAEGGDVTHQHHFVVTFVEDGAVDQVIQGLAVAAGQKAIGLSDPFRGFQEPFP 175
>UniRef50_A5K040 Cluster: GTP cyclohydrolase I, putative; n=1;
Plasmodium vivax|Rep: GTP cyclohydrolase I, putative -
Plasmodium vivax
Length = 423
Score = 39.5 bits (88), Expect = 0.069
Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Frame = +1
Query: 475 PERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEX--TDXMVVVXDIXMFSMCEH 648
P + L T +R L+ TKGY ++ +V+ +++ D + + I ++S+C+H
Sbjct: 240 PPKDILKRTSKRFTDTFLYLTKGYHMNVGKVIKKSLYKRKYKNDSRIKISGIHIYSLCKH 299
Query: 649 HL 654
HL
Sbjct: 300 HL 301
>UniRef50_A0YW77 Cluster: GTP cyclohydrolase I; n=1; Lyngbya sp. PCC
8106|Rep: GTP cyclohydrolase I - Lyngbya sp. PCC 8106
Length = 62
Score = 38.7 bits (86), Expect = 0.12
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = +1
Query: 427 DMANSYRLLLTGLGEDPERAGLLXTPERAAKA 522
+M + R LL GLGE+P+R GL TP+R KA
Sbjct: 31 EMRQAVRTLLLGLGENPDREGLKDTPKRVVKA 62
>UniRef50_Q8RH43 Cluster: GTP cyclohydrolase I; n=3; Fusobacterium
nucleatum|Rep: GTP cyclohydrolase I - Fusobacterium
nucleatum subsp. nucleatum
Length = 187
Score = 37.5 bits (83), Expect = 0.28
Identities = 20/72 (27%), Positives = 38/72 (52%)
Frame = +1
Query: 436 NSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVV 615
N++ ++ LG+ + L TP+R A + G D +EVL F+ ++ +++
Sbjct: 12 NAFFEVIEALGDVEYKEELKDTPKRIADSYKEIFYGIDIDPKEVLTKT-FEVNSNELIME 70
Query: 616 XDIXMFSMCEHH 651
++ +SMCEHH
Sbjct: 71 KNMDFYSMCEHH 82
>UniRef50_A1SM21 Cluster: GTP cyclohydrolase I precursor; n=7;
Actinomycetales|Rep: GTP cyclohydrolase I precursor -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 219
Score = 36.7 bits (81), Expect = 0.49
Identities = 24/68 (35%), Positives = 33/68 (48%)
Frame = +1
Query: 451 LLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDIXM 630
LL LG D E ++ TP R A G D L N +DE +V+V +I +
Sbjct: 47 LLRALGLDIETDEMVETPRRLVAAYHELLTGPDVDLTTFPNTEGYDE----LVLVANIPV 102
Query: 631 FSMCEHHL 654
S+CEHH+
Sbjct: 103 RSVCEHHM 110
>UniRef50_Q5PAR5 Cluster: GTP cyclohydrolase; n=1; Anaplasma
marginale str. St. Maries|Rep: GTP cyclohydrolase -
Anaplasma marginale (strain St. Maries)
Length = 198
Score = 36.3 bits (80), Expect = 0.65
Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
Frame = +1
Query: 427 DMANSYRLLLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIF-DEXTDX 603
D + +L+ + + P+ GL T R A +GY N++F +E
Sbjct: 13 DAEEAIEVLIRWIDDSPDMEGLSLTAGRVLNAYKESFQGYALESSHDFRNSVFANEGYSD 72
Query: 604 MVVVXDIXMFSMCEHHL 654
M+++ + S CEHH+
Sbjct: 73 MILLRGVNFSSTCEHHM 89
>UniRef50_A7HBJ5 Cluster: GTP cyclohydrolase I; n=2;
Anaeromyxobacter|Rep: GTP cyclohydrolase I -
Anaeromyxobacter sp. Fw109-5
Length = 219
Score = 34.7 bits (76), Expect = 2.0
Identities = 32/92 (34%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Frame = +1
Query: 400 RPPGXALLPDMA---NSYRLLLTGLGEDPE-RAG--LLXTPERAAKAMLF-FTKGYDQSL 558
R G + PD A + L LG P+ RA L T R A+A L GY +
Sbjct: 10 RARGSSAAPDAAAAAEAVERFLDALGLPPQVRASPDLQGTHRRVAQAWLEDLVDGYRRDP 69
Query: 559 EEVLNNAIFDEXTDXMVVVXDIXMFSMCEHHL 654
E+L +AI D +V V I S+C HHL
Sbjct: 70 AEILADAIPSPSRD-LVAVTGIAFHSVCPHHL 100
>UniRef50_Q4EE10 Cluster: GTP cyclohydrolase I; n=1; Listeria
monocytogenes str. 4b H7858|Rep: GTP cyclohydrolase I -
Listeria monocytogenes str. 4b H7858
Length = 86
Score = 34.3 bits (75), Expect = 2.6
Identities = 13/30 (43%), Positives = 23/30 (76%)
Frame = +1
Query: 430 MANSYRLLLTGLGEDPERAGLLXTPERAAK 519
+A++ +++L +GE+PER GL+ TP R A+
Sbjct: 30 IADAVKVILEAVGENPEREGLIDTPMRVAR 59
>UniRef50_A4CGT7 Cluster: GTP cyclohydrolase I; n=1; Robiginitalea
biformata HTCC2501|Rep: GTP cyclohydrolase I -
Robiginitalea biformata HTCC2501
Length = 176
Score = 33.9 bits (74), Expect = 3.5
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Frame = +1
Query: 454 LTGLGEDPERAGLLXTPERAAKAMLFFT-KGYDQSLEEVLNNAIFDEX--TDXMVVVXDI 624
+ LG D L TP R A+ + T +G S + + F++ T M+VV DI
Sbjct: 1 MQALGMDLSDTSLADTPMRVARMYVNETFRGL--SAKNFPRISFFEKAPGTPEMIVVNDI 58
Query: 625 XMFSMCEHH 651
++S CEHH
Sbjct: 59 TLYSYCEHH 67
>UniRef50_Q54HA9 Cluster: Pre-mRNA processing factor 31; n=1;
Dictyostelium discoideum AX4|Rep: Pre-mRNA processing
factor 31 - Dictyostelium discoideum AX4
Length = 1054
Score = 33.9 bits (74), Expect = 3.5
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +3
Query: 252 NS*NKMKELNGVSTSQCVETNGALTFTKKXNDNGHENC 365
N N +LNG ++C+E +GA T K NDN ++NC
Sbjct: 401 NEKNGNNDLNG---NKCIEMDGADDLTIKSNDNNYKNC 435
>UniRef50_Q753L6 Cluster: AFR296Cp; n=2; Saccharomycetaceae|Rep:
AFR296Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 1169
Score = 33.9 bits (74), Expect = 3.5
Identities = 18/53 (33%), Positives = 28/53 (52%)
Frame = -1
Query: 554 LWSYPFVKKSIALAARSGVFKSPALSGSSPRPVSRSLYELAMSGNNAXPGGRS 396
LWS P ++++ L V +SP++S S P E A+ GN+ GGR+
Sbjct: 187 LWSAPKLEENDLLRTVVSVSRSPSVSLSRPSSRGGDFVENALDGNSTKNGGRN 239
>UniRef50_Q73PN7 Cluster: Conserved domain protein; n=1; Treponema
denticola|Rep: Conserved domain protein - Treponema
denticola
Length = 165
Score = 33.5 bits (73), Expect = 4.6
Identities = 14/39 (35%), Positives = 23/39 (58%)
Frame = -1
Query: 497 FKSPALSGSSPRPVSRSLYELAMSGNNAXPGGRSVVQXQ 381
FK+P + S P +++YE+ + GNN G S+V+ Q
Sbjct: 22 FKNPEILSSQPSESMQAVYEILIQGNNLKTGLPSIVKSQ 60
>UniRef50_Q83FV8 Cluster: GTP cyclohydrolase I; n=2; Tropheryma
whipplei|Rep: GTP cyclohydrolase I - Tropheryma whipplei
(strain Twist) (Whipple's bacillus)
Length = 181
Score = 32.7 bits (71), Expect = 8.0
Identities = 22/68 (32%), Positives = 34/68 (50%)
Frame = +1
Query: 451 LLTGLGEDPERAGLLXTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEXTDXMVVVXDIXM 630
LL+ LG+D R L TP A+ + G + + + L + I +V++ DI
Sbjct: 19 LLSALGQDVGR--LKETPSIASSGLESLISGSETNPADCLVDLI-PNTQKGIVILRDIPF 75
Query: 631 FSMCEHHL 654
S+CEHHL
Sbjct: 76 RSICEHHL 83
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 634,817,038
Number of Sequences: 1657284
Number of extensions: 12949438
Number of successful extensions: 31110
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 30155
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31066
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49586781480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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