Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P03_F_D06
(493 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 86 7e-20
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 86 7e-20
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 86 7e-20
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 86 7e-20
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 86 7e-20
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 86 4e-17
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 85 1e-16
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 84 2e-16
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 84 2e-16
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 84 2e-16
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 84 2e-16
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 84 2e-16
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 84 2e-16
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 84 2e-16
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 83 4e-16
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 83 4e-16
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 83 4e-16
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 83 4e-16
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 83 4e-16
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 83 4e-16
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 83 4e-16
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 83 4e-16
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 83 4e-16
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 83 4e-16
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 83 4e-16
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 83 4e-16
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 83 7e-16
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 82 1e-15
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 82 1e-15
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 81 2e-15
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 81 2e-15
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 81 2e-15
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 81 2e-15
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 81 2e-15
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 81 2e-15
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 81 2e-15
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 81 2e-15
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 81 2e-15
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 81 2e-15
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 81 2e-15
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 81 2e-15
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 81 2e-15
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 81 2e-15
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 81 2e-15
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 81 2e-15
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 81 2e-15
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 81 2e-15
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 81 2e-15
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 81 2e-15
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 81 2e-15
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 81 2e-15
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 81 2e-15
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 81 2e-15
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 81 2e-15
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 81 2e-15
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 81 2e-15
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 81 2e-15
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 81 2e-15
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 81 2e-15
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 81 2e-15
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 80 4e-15
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 80 4e-15
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 80 4e-15
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 80 4e-15
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 80 4e-15
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 80 4e-15
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 80 4e-15
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 80 4e-15
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 79 8e-15
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 78 1e-14
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 77 4e-14
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 76 8e-14
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 75 1e-13
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 73 7e-13
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 72 9e-13
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 72 9e-13
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 72 9e-13
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 72 9e-13
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 72 9e-13
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 68 2e-11
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 68 2e-11
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 68 2e-11
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 68 2e-11
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 39 0.008
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 32 0.94
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 32 0.94
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 32 0.94
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 32 0.94
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 86.2 bits (204), Expect(2) = 7e-20
Identities = 34/68 (50%), Positives = 51/68 (75%)
Frame = +3
Query: 198 FFXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
F+ E+E+G ++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+D+
Sbjct: 39 FYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDL 98
Query: 378 YLMHWPIG 401
YL+HWP+G
Sbjct: 99 YLIHWPMG 106
Score = 31.9 bits (69), Expect = 1.2
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 62 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
D+PA+GL ++ K+ ++ + V AID GYRHF A + N
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHN 42
Score = 30.3 bits (65), Expect(2) = 7e-20
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = +3
Query: 423 SDVDFMETWRGLEDAQRMGIVK 488
SD DF++TW +ED G+VK
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 86.2 bits (204), Expect(2) = 7e-20
Identities = 34/68 (50%), Positives = 51/68 (75%)
Frame = +3
Query: 198 FFXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
F+ E+E+G ++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+D+
Sbjct: 39 FYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDL 98
Query: 378 YLMHWPIG 401
YL+HWP+G
Sbjct: 99 YLIHWPMG 106
Score = 31.9 bits (69), Expect = 1.2
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 62 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
D+PA+GL ++ K+ ++ + V AID GYRHF A + N
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHN 42
Score = 30.3 bits (65), Expect(2) = 7e-20
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = +3
Query: 423 SDVDFMETWRGLEDAQRMGIVK 488
SD DF++TW +ED G+VK
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 86.2 bits (204), Expect(2) = 7e-20
Identities = 34/68 (50%), Positives = 51/68 (75%)
Frame = +3
Query: 198 FFXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
F+ E+E+G ++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+D+
Sbjct: 39 FYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDL 98
Query: 378 YLMHWPIG 401
YL+HWP+G
Sbjct: 99 YLIHWPMG 106
Score = 31.9 bits (69), Expect = 1.2
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 62 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
D+PA+GL ++ K+ ++ + V AID GYRHF A + N
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHN 42
Score = 30.3 bits (65), Expect(2) = 7e-20
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = +3
Query: 423 SDVDFMETWRGLEDAQRMGIVK 488
SD DF++TW +ED G+VK
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 86.2 bits (204), Expect(2) = 7e-20
Identities = 34/68 (50%), Positives = 51/68 (75%)
Frame = +3
Query: 198 FFXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
F+ E+E+G ++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+D+
Sbjct: 39 FYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDL 98
Query: 378 YLMHWPIG 401
YL+HWP+G
Sbjct: 99 YLIHWPMG 106
Score = 31.9 bits (69), Expect = 1.2
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 62 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
D+PA+GL ++ K+ ++ + V AID GYRHF A + N
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHN 42
Score = 30.3 bits (65), Expect(2) = 7e-20
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = +3
Query: 423 SDVDFMETWRGLEDAQRMGIVK 488
SD DF++TW +ED G+VK
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 86.2 bits (204), Expect(2) = 7e-20
Identities = 34/68 (50%), Positives = 51/68 (75%)
Frame = +3
Query: 198 FFXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
F+ E+E+G ++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+D+
Sbjct: 39 FYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDL 98
Query: 378 YLMHWPIG 401
YL+HWP+G
Sbjct: 99 YLIHWPMG 106
Score = 31.9 bits (69), Expect = 1.2
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 62 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
D+PA+GL ++ K+ ++ + V AID GYRHF A + N
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHN 42
Score = 30.3 bits (65), Expect(2) = 7e-20
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = +3
Query: 423 SDVDFMETWRGLEDAQRMGIVK 488
SD DF++TW +ED G+VK
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 86.2 bits (204), Expect(2) = 4e-17
Identities = 34/68 (50%), Positives = 51/68 (75%)
Frame = +3
Query: 198 FFXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
F+ E+E+G ++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+D+
Sbjct: 39 FYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDL 98
Query: 378 YLMHWPIG 401
YL+HWP+G
Sbjct: 99 YLIHWPMG 106
Score = 31.9 bits (69), Expect = 1.2
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 62 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
D+PA+GL ++ K+ ++ + V AID GYRHF A + N
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHN 42
Score = 21.0 bits (42), Expect(2) = 4e-17
Identities = 6/9 (66%), Positives = 8/9 (88%)
Frame = +3
Query: 423 SDVDFMETW 449
SD DF++TW
Sbjct: 144 SDTDFLDTW 152
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 85.4 bits (202), Expect = 1e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 34.7 bits (76), Expect = 0.18
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVSKLAIEAGFRHIDSAHLYNN 57
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 84.2 bits (199), Expect = 2e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 57 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 116
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 117 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 163
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 59
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 84.2 bits (199), Expect = 2e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 84.2 bits (199), Expect = 2e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 84.2 bits (199), Expect = 2e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 84.2 bits (199), Expect = 2e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 84.2 bits (199), Expect = 2e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 84.2 bits (199), Expect = 2e-16
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 83.4 bits (197), Expect = 4e-16
Identities = 41/107 (38%), Positives = 62/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWPIG + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 68 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 127
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 128 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 174
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 17 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 68
Query: 203 XN 208
N
Sbjct: 69 NN 70
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 83.4 bits (197), Expect = 4e-16
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 37.1 bits (82), Expect = 0.033
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ G+ H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 82.6 bits (195), Expect = 7e-16
Identities = 42/107 (39%), Positives = 64/107 (59%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G V+REDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 81.8 bits (193), Expect = 1e-15
Identities = 42/107 (39%), Positives = 63/107 (58%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G V REDIF T+KLW+T HR V A+ +SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V +SK +V AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNN 57
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 81.8 bits (193), Expect = 1e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
Score = 38.7 bits (86), Expect = 0.011
Identities = 23/62 (37%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + V AI+ GY H +A V+
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGYHHIDSAHVY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/57 (43%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
R+ +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RILLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 38 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 97
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 98 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 144
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 46 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 105
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++TW +E+ G+VK
Sbjct: 106 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVK 152
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 1 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 48
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + G+ K
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 161
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 4 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 55
Query: 203 XN 208
N
Sbjct: 56 NN 57
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 81.0 bits (191), Expect = 2e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 381 LMHWPIGLNA--DYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+HWP G + D D F++ W +E+ G+VK
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVK 155
Score = 32.7 bits (71), Expect = 0.71
Identities = 19/56 (33%), Positives = 30/56 (53%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++++ MP +GLGT+ KS ++++ V AID GYRH A V+ N
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQN 51
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/107 (40%), Positives = 61/107 (57%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G AV+ K+ +G VKREDIF T+KLW HR V A+ SLKK LDY+D+Y
Sbjct: 55 YNNEEQVGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLY 114
Query: 381 LMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+H P+ L + S +D VD TW +E + G+ K
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
Score = 35.9 bits (79), Expect = 0.076
Identities = 20/56 (35%), Positives = 31/56 (55%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++ N
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLYNN 57
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 81.0 bits (191), Expect = 2e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 381 LMHWPIGLNA--DYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+HWP G + D D F++ W +E+ G+VK
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVK 155
Score = 32.7 bits (71), Expect = 0.71
Identities = 19/56 (33%), Positives = 30/56 (53%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++++ MP +GLGT+ KS ++++ V AID GYRH A V+ N
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQN 51
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 81.0 bits (191), Expect = 2e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 381 LMHWPIGLNA--DYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+HWP G + D D F++ W +E+ G+VK
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVK 155
Score = 32.7 bits (71), Expect = 0.71
Identities = 19/56 (33%), Positives = 30/56 (53%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++++ MP +GLGT+ KS ++++ V AID GYRH A V+ N
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQN 51
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 81.0 bits (191), Expect = 2e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 381 LMHWPIGLNA--DYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+HWP G + D D F++ W +E+ G+VK
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVK 155
Score = 32.7 bits (71), Expect = 0.71
Identities = 19/56 (33%), Positives = 30/56 (53%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++++ MP +GLGT+ KS ++++ V AID GYRH A V+ N
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQN 51
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 81.0 bits (191), Expect = 2e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 381 LMHWPIGLNA--DYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+HWP G + D D F++ W +E+ G+VK
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVK 155
Score = 32.7 bits (71), Expect = 0.71
Identities = 19/56 (33%), Positives = 30/56 (53%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++++ MP +GLGT+ KS ++++ V AID GYRH A V+ N
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQN 51
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 81.0 bits (191), Expect = 2e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVK 488
YLMHWP NAD + + ETW+ LE G+V+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQ 157
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAK 161
Score = 33.5 bits (73), Expect = 0.41
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +2
Query: 29 KCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
K R+++N+G MP +G GTY + + +V AI+ G+RH +A ++ N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 40 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 99
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 100 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAK 146
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 53 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 112
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 113 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAK 159
Score = 33.5 bits (73), Expect = 0.41
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +2
Query: 29 KCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
K R+++N+G MP +G GTY + + +V AI+ G+RH +A ++ N
Sbjct: 2 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 55
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAK 161
Score = 33.5 bits (73), Expect = 0.41
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +2
Query: 29 KCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
K R+++N+G MP +G GTY + + +V AI+ G+RH +A ++ N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAK 161
Score = 33.5 bits (73), Expect = 0.41
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +2
Query: 29 KCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
K R+++N+G MP +G GTY + + +V AI+ G+RH +A ++ N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAK 161
Score = 33.5 bits (73), Expect = 0.41
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +2
Query: 29 KCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
K R+++N+G MP +G GTY + + +V AI+ G+RH +A ++ N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAK 161
Score = 33.5 bits (73), Expect = 0.41
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +2
Query: 29 KCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
K R+++N+G MP +G GTY + + +V AI+ G+RH +A ++ N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 80.2 bits (189), Expect = 4e-15
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+D+Y
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ L N VD TW +E + G+ K
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAK 161
Score = 33.5 bits (73), Expect = 0.41
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +2
Query: 29 KCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
K R+++N+G MP +G GTY + + +V AI+ G+RH +A ++ N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 79.0 bits (186), Expect = 8e-15
Identities = 40/102 (39%), Positives = 56/102 (54%), Gaps = 11/102 (10%)
Frame = +3
Query: 216 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIYLMHWP 395
E+G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+D+YL+H+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 396 IGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
+ + N VD TW +E + G+ K
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAK 127
Score = 29.1 bits (62), Expect = 8.8
Identities = 12/35 (34%), Positives = 22/35 (62%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSK 127
+++C +K+N+G MP +G GTY + ++SK
Sbjct: 2 KYQC--VKLNDGHFMPVLGFGTYAPAEVGLAIRSK 34
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 78.2 bits (184), Expect = 1e-14
Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K++E VKRED+FI +KLW T R V +A +LK L Y+D+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVY 108
Query: 381 LMHWPIGLNA--DYSHSD---------VDFMETWRGLEDAQRMGIVK 488
L+HWP G + D D F++ W +E+ G+VK
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVK 155
Score = 32.7 bits (71), Expect = 0.71
Identities = 19/56 (33%), Positives = 30/56 (53%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++++ MP +GLGT+ KS ++++ V AID GYRH A V+ N
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQN 51
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 76.6 bits (180), Expect = 4e-14
Identities = 40/98 (40%), Positives = 56/98 (57%), Gaps = 12/98 (12%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDI 377
+ E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+D+
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 378 YLMHWPIGL---------NAD--YSHSDVDFMETWRGL 458
YLMHWP NAD + + ETW+ L
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Score = 37.9 bits (84), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 47 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH A+++ N
Sbjct: 8 LHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGN 52
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 75.8 bits (178), Expect = 8e-14
Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+D+Y
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+HWP G + + SD + ++T +E+ G+VK
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVK 155
Score = 45.6 bits (103), Expect = 9e-05
Identities = 26/57 (45%), Positives = 32/57 (56%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
RL +NNG MP +GLGT+ KS Q+ + V AIDVGYRH A V+ N
Sbjct: 4 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQN 51
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 75.4 bits (177), Expect = 1e-13
Identities = 38/107 (35%), Positives = 57/107 (53%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+++G A++ K+ +G VKREDIF T+KLW HR A+ SLK L LDY+D+Y
Sbjct: 52 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLY 111
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
L+H+P+ + N VD TW +E + + K
Sbjct: 112 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAK 158
Score = 36.3 bits (80), Expect = 0.058
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +2
Query: 23 RWKCPRLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVF 202
+++C +K+N+G MP +G GTY + V KSK + AI+ G+RH +A ++
Sbjct: 1 KYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEATKLAIEAGFRHIDSAHLY 52
Query: 203 XN 208
N
Sbjct: 53 NN 54
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 72.5 bits (170), Expect = 7e-13
Identities = 32/65 (49%), Positives = 45/65 (69%)
Frame = +3
Query: 210 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIYLMH 389
E+ IG+A++ K+ G VKR+DIF TTK+W T R V + + SLKKL L Y+D+YL H
Sbjct: 59 EEGIGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFH 118
Query: 390 WPIGL 404
+P+ L
Sbjct: 119 FPVPL 123
Score = 35.5 bits (78), Expect = 0.10
Identities = 20/56 (35%), Positives = 29/56 (51%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+K+N+G+ MP +G GT + K + + V AIDVGYRH +A N
Sbjct: 9 VKLNDGKFMPILGFGTSVAR------KVAMSNVEEAVQVAIDVGYRHIDSAYTHLN 58
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 72.1 bits (169), Expect = 9e-13
Identities = 31/68 (45%), Positives = 46/68 (67%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+E+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+D++
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 381 LMHWPIGL 404
++H P +
Sbjct: 118 IIHVPFAM 125
Score = 35.1 bits (77), Expect = 0.13
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+++N+G MP +G GTY + KS+ + V AIDVG+RH +A ++ N
Sbjct: 11 VRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQN 60
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 72.1 bits (169), Expect = 9e-13
Identities = 31/68 (45%), Positives = 46/68 (67%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+E+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+D++
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 381 LMHWPIGL 404
++H P +
Sbjct: 118 IIHVPFAM 125
Score = 35.1 bits (77), Expect = 0.13
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+++N+G MP +G GTY + KS+ + V AIDVG+RH +A ++ N
Sbjct: 11 VRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQN 60
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 72.1 bits (169), Expect = 9e-13
Identities = 31/68 (45%), Positives = 46/68 (67%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+E+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+D++
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 381 LMHWPIGL 404
++H P +
Sbjct: 118 IIHVPFAM 125
Score = 35.1 bits (77), Expect = 0.13
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+++N+G MP +G GTY + KS+ + V AIDVG+RH +A ++ N
Sbjct: 11 VRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQN 60
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 72.1 bits (169), Expect = 9e-13
Identities = 31/68 (45%), Positives = 46/68 (67%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+E+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+D++
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 381 LMHWPIGL 404
++H P +
Sbjct: 118 IIHVPFAM 125
Score = 35.1 bits (77), Expect = 0.13
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+++N+G MP +G GTY + KS+ + V AIDVG+RH +A ++ N
Sbjct: 11 VRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQN 60
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 72.1 bits (169), Expect = 9e-13
Identities = 31/68 (45%), Positives = 46/68 (67%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E+E+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+D++
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 381 LMHWPIGL 404
++H P +
Sbjct: 118 IIHVPFAM 125
Score = 35.1 bits (77), Expect = 0.13
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 41 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFXTASVFXN 208
+++N+G MP +G GTY + KS+ + V AIDVG+RH +A ++ N
Sbjct: 11 VRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQN 60
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+D+Y
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
++ P+ N + + + TW +E + G+VK
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVK 164
Score = 34.3 bits (75), Expect = 0.23
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFXTASVFXN 208
R+ +++G +P IGLGTY KS K V AID GYRH A ++ N
Sbjct: 9 RIPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN 60
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+D+Y
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
++ P+ N + + + TW +E + G+VK
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVK 164
Score = 34.3 bits (75), Expect = 0.23
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFXTASVFXN 208
R+ +++G +P IGLGTY KS K V AID GYRH A ++ N
Sbjct: 9 RIPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN 60
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+D+Y
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
++ P+ N + + + TW +E + G+VK
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVK 164
Score = 34.3 bits (75), Expect = 0.23
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFXTASVFXN 208
R+ +++G +P IGLGTY KS K V AID GYRH A ++ N
Sbjct: 9 RIPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN 60
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 11/107 (10%)
Frame = +3
Query: 201 FXTEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDIY 380
+ E E+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+D+Y
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 381 LMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVK 488
++ P+ N + + + TW +E + G+VK
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVK 164
Score = 34.3 bits (75), Expect = 0.23
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 38 RLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFXTASVFXN 208
R+ +++G +P IGLGTY KS K V AID GYRH A ++ N
Sbjct: 9 RIPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN 60
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 39.1 bits (87), Expect = 0.008
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +3
Query: 291 LWNTQHRRTEVAQAINDSLKKLGLDYIDIYLMHWPIGL 404
+W T R V + + SLKKL L Y+D+YL H+P+ L
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38
>AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 32.3 bits (70), Expect = 0.94
Identities = 14/36 (38%), Positives = 15/36 (41%)
Frame = -3
Query: 110 RSDQTQGTCPGRWRACLCRCSFLXEGTSIVDASPSP 3
R Q GTC RW LC C G + A P P
Sbjct: 1656 RRCQNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHP 1691
>AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 32.3 bits (70), Expect = 0.94
Identities = 14/36 (38%), Positives = 15/36 (41%)
Frame = -3
Query: 110 RSDQTQGTCPGRWRACLCRCSFLXEGTSIVDASPSP 3
R Q GTC RW LC C G + A P P
Sbjct: 1656 RRCQNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHP 1691
>AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 32.3 bits (70), Expect = 0.94
Identities = 14/36 (38%), Positives = 15/36 (41%)
Frame = -3
Query: 110 RSDQTQGTCPGRWRACLCRCSFLXEGTSIVDASPSP 3
R Q GTC RW LC C G + A P P
Sbjct: 1656 RRCQNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHP 1691
>AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo 2
protein.
Length = 3014
Score = 32.3 bits (70), Expect = 0.94
Identities = 14/36 (38%), Positives = 15/36 (41%)
Frame = -3
Query: 110 RSDQTQGTCPGRWRACLCRCSFLXEGTSIVDASPSP 3
R Q GTC RW LC C G + A P P
Sbjct: 1656 RRCQNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHP 1691
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,558,862
Number of Sequences: 237096
Number of extensions: 1490628
Number of successful extensions: 3004
Number of sequences better than 10.0: 95
Number of HSP's better than 10.0 without gapping: 2752
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2918
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4423060356
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -