Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P03_F_B20
(654 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 297 2e-80
DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 297 2e-80
BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 297 2e-80
BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 297 2e-80
AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 297 2e-80
X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 282 9e-76
D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 282 9e-76
BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 282 9e-76
AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 282 9e-76
AL359195-3|CAI13696.1| 145|Homo sapiens methionine adenosyltran... 135 1e-31
BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, mem... 30 6.3
AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein. 30 8.3
AK022147-1|BAB13971.1| 674|Homo sapiens protein ( Homo sapiens ... 30 8.3
>X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 297 bits (730), Expect = 2e-80
Identities = 141/188 (75%), Positives = 160/188 (85%), Gaps = 1/188 (0%)
Frame = +3
Query: 90 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACE 266
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+L AHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 267 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNI 446
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 447 AAGVHXNRNDEEVGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWAR 626
A GVH +RN+E++GAGD GLMFGYAT TE CMPLT+VLAHKLN K+AEL RNG W R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 627 PXSKTQVT 650
P SKTQVT
Sbjct: 178 PDSKTQVT 185
>DQ083239-1|AAY85355.1| 395|Homo sapiens methionine
adenosyltransferase II protein.
Length = 395
Score = 297 bits (730), Expect = 2e-80
Identities = 141/188 (75%), Positives = 160/188 (85%), Gaps = 1/188 (0%)
Frame = +3
Query: 90 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACE 266
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+L AHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 267 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNI 446
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 447 AAGVHXNRNDEEVGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWAR 626
A GVH +RN+E++GAGD GLMFGYAT TE CMPLT+VLAHKLN K+AEL RNG W R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 627 PXSKTQVT 650
P SKTQVT
Sbjct: 178 PDSKTQVT 185
>BC001854-1|AAH01854.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 297 bits (730), Expect = 2e-80
Identities = 141/188 (75%), Positives = 160/188 (85%), Gaps = 1/188 (0%)
Frame = +3
Query: 90 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACE 266
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+L AHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 267 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNI 446
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 447 AAGVHXNRNDEEVGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWAR 626
A GVH +RN+E++GAGD GLMFGYAT TE CMPLT+VLAHKLN K+AEL RNG W R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 627 PXSKTQVT 650
P SKTQVT
Sbjct: 178 PDSKTQVT 185
>BC001686-1|AAH01686.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 297 bits (730), Expect = 2e-80
Identities = 141/188 (75%), Positives = 160/188 (85%), Gaps = 1/188 (0%)
Frame = +3
Query: 90 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACE 266
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+L AHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 267 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNI 446
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 447 AAGVHXNRNDEEVGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWAR 626
A GVH +RN+E++GAGD GLMFGYAT TE CMPLT+VLAHKLN K+AEL RNG W R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 627 PXSKTQVT 650
P SKTQVT
Sbjct: 178 PDSKTQVT 185
>AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein.
Length = 395
Score = 297 bits (730), Expect = 2e-80
Identities = 141/188 (75%), Positives = 160/188 (85%), Gaps = 1/188 (0%)
Frame = +3
Query: 90 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACE 266
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+L AHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 267 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNI 446
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 447 AAGVHXNRNDEEVGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWAR 626
A GVH +RN+E++GAGD GLMFGYAT TE CMPLT+VLAHKLN K+AEL RNG W R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 627 PXSKTQVT 650
P SKTQVT
Sbjct: 178 PDSKTQVT 185
>X69078-1|CAA48822.1| 395|Homo sapiens methionine
adenosyltransferase protein.
Length = 395
Score = 282 bits (691), Expect = 9e-76
Identities = 127/176 (72%), Positives = 153/176 (86%)
Frame = +3
Query: 123 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACETITKTGMVLLCG 302
+ + +G VF+FTSESVGEGHPDK+CDQISDA+L AHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 303 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNIAAGVHXNRNDEE 482
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 483 VGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWARPXSKTQVT 650
VGAGD GLMFGYAT TE CMPLT++LAHKLN ++A+L R+G W RP SKTQVT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVT 185
>D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 282 bits (691), Expect = 9e-76
Identities = 127/176 (72%), Positives = 153/176 (86%)
Frame = +3
Query: 123 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACETITKTGMVLLCG 302
+ + +G VF+FTSESVGEGHPDK+CDQISDA+L AHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 303 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNIAAGVHXNRNDEE 482
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 483 VGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWARPXSKTQVT 650
VGAGD GLMFGYAT TE CMPLT++LAHKLN ++A+L R+G W RP SKTQVT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVT 185
>BC018359-1|AAH18359.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 282 bits (691), Expect = 9e-76
Identities = 127/176 (72%), Positives = 153/176 (86%)
Frame = +3
Query: 123 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACETITKTGMVLLCG 302
+ + +G VF+FTSESVGEGHPDK+CDQISDA+L AHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 303 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNIAAGVHXNRNDEE 482
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 483 VGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWARPXSKTQVT 650
VGAGD GLMFGYAT TE CMPLT++LAHKLN ++A+L R+G W RP SKTQVT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVT 185
>AL359195-2|CAI13695.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 282 bits (691), Expect = 9e-76
Identities = 127/176 (72%), Positives = 153/176 (86%)
Frame = +3
Query: 123 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACETITKTGMVLLCG 302
+ + +G VF+FTSESVGEGHPDK+CDQISDA+L AHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 303 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALXQQSPNIAAGVHXNRNDEE 482
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 483 VGAGDXGLMFGYATXXTEXCMPLTVVLAHKLNXKIAELXRNGXFWWARPXSKTQVT 650
VGAGD GLMFGYAT TE CMPLT++LAHKLN ++A+L R+G W RP SKTQVT
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVT 185
>AL359195-3|CAI13696.1| 145|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 145
Score = 135 bits (327), Expect = 1e-31
Identities = 62/100 (62%), Positives = 79/100 (79%), Gaps = 3/100 (3%)
Frame = +3
Query: 360 HIGYDDSSK---GFDYKTCSVMLALXQQSPNIAAGVHXNRNDEEVGAGDXGLMFGYATXX 530
H+ D ++K GFD+KTC+V++AL QQSP+IA VH +RN+E+VGAGD GLMFGYAT
Sbjct: 23 HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDE 82
Query: 531 TEXCMPLTVVLAHKLNXKIAELXRNGXFWWARPXSKTQVT 650
TE CMPLT++LAHKLN ++A+L R+G W RP SKTQVT
Sbjct: 83 TEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVT 122
Score = 72.9 bits (171), Expect = 9e-13
Identities = 41/81 (50%), Positives = 48/81 (59%)
Frame = +3
Query: 162 ESVGEGHPDKMCDQISDAILXAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKV 341
ESVGEGHPDK+CDQISDA+L AHL QDP+AKVAC KT VL+ E S +
Sbjct: 1 ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHL 60
Query: 342 VRETVKHIGYDDSSKGFDYKT 404
R + +G D F Y T
Sbjct: 61 DRNE-EDVGAGDQGLMFGYAT 80
>BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, member
15 protein.
Length = 691
Score = 30.3 bits (65), Expect = 6.3
Identities = 20/66 (30%), Positives = 31/66 (46%)
Frame = +3
Query: 51 WANSKFRMPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAH 230
W K + P T+ M G++K + +D GS S + P +M D +SDAI
Sbjct: 235 WKKIK-KDPYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLK 288
Query: 231 LNQDPD 248
+NQ +
Sbjct: 289 INQQEE 294
>AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein.
Length = 1211
Score = 29.9 bits (64), Expect = 8.3
Identities = 14/27 (51%), Positives = 15/27 (55%)
Frame = -3
Query: 514 PNIKPWSPAPTSSSFLXSCTPAAMFGD 434
P+ PWSPA TSS L S P GD
Sbjct: 1178 PDEPPWSPAATSSGNLSSRGPGPATGD 1204
>AK022147-1|BAB13971.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ12085 fis, clone HEMBB1002510, weakly similar to
GYP7 PROTEIN. ).
Length = 674
Score = 29.9 bits (64), Expect = 8.3
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +3
Query: 75 PETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILXAHLNQDPD 248
P T+ M G++K + +D GS S + P +M D +SDAI +NQ +
Sbjct: 225 PYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLKINQQEE 277
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,310,661
Number of Sequences: 237096
Number of extensions: 1953090
Number of successful extensions: 3003
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2933
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3003
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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