Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P02_F_N11
(650 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|R... 158 1e-37
UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to N-acetylne... 135 8e-31
UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA ... 125 1e-27
UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 92 9e-18
UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16; Bac... 86 8e-16
UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;... 77 4e-13
UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;... 71 3e-11
UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n... 68 2e-10
UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides ... 65 1e-09
UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;... 65 1e-09
UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzy... 65 2e-09
UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;... 65 2e-09
UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate synth... 64 2e-09
UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1; Me... 64 3e-09
UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;... 64 4e-09
UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3; cell... 63 5e-09
UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein, pu... 62 1e-08
UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis p... 59 1e-07
UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid synth... 58 1e-07
UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1; Clos... 58 2e-07
UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides ... 56 6e-07
UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococ... 56 6e-07
UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Re... 56 7e-07
UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3; Proteobacter... 56 1e-06
UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;... 56 1e-06
UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Re... 55 1e-06
UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzy... 55 2e-06
UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep... 54 2e-06
UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;... 54 2e-06
UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis pr... 54 4e-06
UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2; Gammaproteob... 53 5e-06
UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7; ... 52 1e-05
UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid) s... 52 2e-05
UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococ... 52 2e-05
UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium ja... 51 3e-05
UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1; Ente... 50 6e-05
UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;... 50 6e-05
UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1; Magn... 50 6e-05
UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid) s... 49 1e-04
UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;... 48 1e-04
UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;... 48 2e-04
UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellula... 46 6e-04
UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB - Escheri... 45 0.001
UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n... 45 0.002
UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium b... 44 0.003
UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis ... 43 0.006
UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1; Gram... 42 0.010
UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular organ... 42 0.013
UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema den... 42 0.017
UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB p... 42 0.017
UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB - A... 41 0.030
UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.... 41 0.030
UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1; Alte... 41 0.030
UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas s... 40 0.039
UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular or... 40 0.068
UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;... 39 0.090
UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4; Bact... 39 0.090
UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like p... 39 0.090
UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2... 39 0.090
UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;... 38 0.16
UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17; Bacteria|... 37 0.36
UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 37 0.48
UniRef50_Q9LN03 Cluster: T6D22.13; n=2; Arabidopsis thaliana|Rep... 36 0.84
UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococ... 36 1.1
UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1; Mari... 35 1.5
>UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|Rep:
Sialic acid synthase - Homo sapiens (Human)
Length = 359
Score = 158 bits (383), Expect = 1e-37
Identities = 74/133 (55%), Positives = 89/133 (66%)
Frame = +2
Query: 188 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKF 367
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 368 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFL 547
+K LERPY + +SWGKTYGEHK HLEFS QYR L YA+EVGI FTAS MD ++ +FL
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFL 122
Query: 548 VNLKVPFIKIGSG 586
L VPF K+GSG
Sbjct: 123 HELNVPFFKVGSG 135
>UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to
N-acetylneuraminic acid phosphate synthase; n=1; Macaca
mulatta|Rep: PREDICTED: similar to N-acetylneuraminic
acid phosphate synthase - Macaca mulatta
Length = 274
Score = 135 bits (327), Expect = 8e-31
Identities = 63/113 (55%), Positives = 75/113 (66%)
Frame = +2
Query: 188 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKF 367
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 368 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMD 526
+K LERPY + +SWGKTYGEHK HLEF+ QYR L YA+EVGI FTAS MD
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFNHDQYRELQRYAEEVGIFFTASGMD 115
>UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA -
Drosophila melanogaster (Fruit fly)
Length = 372
Score = 125 bits (301), Expect = 1e-27
Identities = 63/125 (50%), Positives = 76/125 (60%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGK 418
+IIAE GQNHQG G CVKFQK+ L KFT+ L+R Y + ++WGK
Sbjct: 16 YIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGK 75
Query: 419 TYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGLEQ 598
TYGEHK +LEFS QY L + +E+ + FTASAMD S +FL L VPFIKIGSG
Sbjct: 76 TYGEHKEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANN 135
Query: 599 LALPK 613
L K
Sbjct: 136 FPLLK 140
>UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris BisA53|Rep:
N-acetylneuraminate synthase - Rhodopseudomonas
palustris (strain BisA53)
Length = 357
Score = 92.3 bits (219), Expect = 9e-18
Identities = 49/128 (38%), Positives = 65/128 (50%)
Frame = +2
Query: 230 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNS 409
NP F+IAE G NHQGD GA VK QK FT + + YD+ N+
Sbjct: 16 NPSFVIAEVGHNHQGDIEKCKAIFKAAKEAGADAVKIQKRDNRALFTAEMYDSHYDSENA 75
Query: 410 WGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGG 589
+ TYG H+ LEF+ QY L Y +++ ILF ++A D S + L + +P KI SG
Sbjct: 76 YAHTYGTHRECLEFNREQYLELKEYCKQLDILFFSTAFDEPSAELLEEIDMPGFKIASGD 135
Query: 590 LEQLALPK 613
L L K
Sbjct: 136 LVNTPLLK 143
>UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16;
Bacteria|Rep: N-acetylneuraminate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 300
Score = 85.8 bits (203), Expect = 8e-16
Identities = 45/125 (36%), Positives = 63/125 (50%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYD 397
+G + PC++IAE G NH GD G VKFQK + +T L +P +
Sbjct: 20 VGKDQPCYVIAEIGINHNGDMDIAKRLISVAVGAGCDAVKFQKRTIDVVYTAAELAKPRE 79
Query: 398 NPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 577
NP +G T G+ K LEF +++ + Y +EV + + ASA D S DF+ VP KI
Sbjct: 80 NP--FGATNGDLKRGLEFGLEEFKEIDRYCREVRMPWFASAWDEASVDFIAQFDVPCFKI 137
Query: 578 GSGGL 592
S L
Sbjct: 138 ASASL 142
>UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Caulobacter sp. K31
Length = 310
Score = 77.0 bits (181), Expect = 4e-13
Identities = 42/118 (35%), Positives = 57/118 (48%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGK 418
F+IAE G NH GD G VKFQK + +T + L +P +P WG
Sbjct: 34 FVIAEIGINHNGDLEITKQLIRAARDAGCDAVKFQKRTIDIVYTPEVLAQPRQSP--WGD 91
Query: 419 TYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGL 592
T K LEF +Y + Y +E+G+ + ASA D+ S FL +P+ KI S L
Sbjct: 92 TQRAQKEGLEFGKAEYDVIDAYCRELGLAWFASAWDVPSQTFLAAYDLPYNKIASAML 149
>UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Stappia aggregata IAM 12614|Rep:
N-acylneuraminate-9-phosphate synthase - Stappia
aggregata IAM 12614
Length = 287
Score = 70.5 bits (165), Expect = 3e-11
Identities = 40/115 (34%), Positives = 57/115 (49%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGK 418
++IAE G NH GD G VKFQK + ++ + L RP +N +G
Sbjct: 8 YVIAEIGINHNGDIDQALEMIRKSKEAGCDAVKFQKRTVDVVYSAEELARPRENV--FGT 65
Query: 419 TYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 583
T G+ K LEF Y + +E+GI + AS D S DFL++ P+IK+ S
Sbjct: 66 TNGDLKRGLEFGKADYDRIDKLCKELGIDWFASPWDEGSVDFLLDYDTPYIKVAS 120
>UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n=1;
unknown|Rep: UPI00015B984F UniRef100 entry - unknown
Length = 361
Score = 67.7 bits (158), Expect = 2e-10
Identities = 41/126 (32%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYD 397
IG + CF+IAEAG NH GD GA +KFQ + + Y
Sbjct: 23 IGNDGRCFVIAEAGVNHNGDVAMAHRLIDVAAAAGADAIKFQTFNAETLVDRSARKAAYQ 82
Query: 398 NPNSWGK-TYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 574
N+ + + E LE YR L +A + GI ++ D S DFL L VP K
Sbjct: 83 VTNTGSESSQFEMLRSLELPAQAYRALQDHAGQAGIALISTPFDEASVDFLATLGVPAYK 142
Query: 575 IGSGGL 592
+ SG L
Sbjct: 143 VSSGDL 148
>UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides
vulgatus ATCC 8482|Rep: Sialic acid synthase -
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
11154)
Length = 334
Score = 65.3 bits (152), Expect = 1e-09
Identities = 41/126 (32%), Positives = 56/126 (44%), Gaps = 2/126 (1%)
Frame = +2
Query: 230 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNS 409
N +IIAEAG NH G GA VKFQ T+ Y N
Sbjct: 3 NHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQTWKTEKIVTRNAELAVYQENNI 62
Query: 410 WGKTYGEHK--SHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 583
KT + K LE S + + + E+GI F ++ ++ S DFL N +PFIK+GS
Sbjct: 63 SDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLGS 122
Query: 584 GGLEQL 601
G + +
Sbjct: 123 GDVTNI 128
>UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 349
Score = 65.3 bits (152), Expect = 1e-09
Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
RI P +IIAE G NH G+ GA+ VKFQK L + + L+ P
Sbjct: 14 RISTKEPAYIIAEIGINHNGNITTAKKLIDVAVDAGANAVKFQKRSLNDIYREDVLKDP- 72
Query: 395 DNPNSWG-KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFI 571
N S G + + + +EF D Y+ L Y +E I F + D+ S +FL +P
Sbjct: 73 -NIESQGLEILLDVLNEVEFDDDAYKELTEYCKEKHITFLCTPWDIPSVEFLEKFDLPAY 131
Query: 572 KIGSGGLEQLAL 607
KI S + L
Sbjct: 132 KIASADMTNFPL 143
>UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzyme;
n=6; Bacteria|Rep: N-acetylneuraminic acid condensing
enzyme - Legionella pneumophila
Length = 338
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/118 (35%), Positives = 52/118 (44%), Gaps = 1/118 (0%)
Frame = +2
Query: 236 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNS-W 412
CFIIAEAG NH GD GA VKFQ K + Y N+
Sbjct: 3 CFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQTFKADTLVNKTVEKAEYQKNNAPE 62
Query: 413 GKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 586
T E LE S+ + L A +GI F ++ D S DFL++L V +KI SG
Sbjct: 63 SSTQYEMLKALELSEEDHYLLSELANSLGIEFMSTGFDEQSIDFLISLGVKRLKIPSG 120
>UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Fulvimarina pelagi HTCC2506|Rep:
N-acylneuraminate-9-phosphate synthase - Fulvimarina
pelagi HTCC2506
Length = 347
Score = 64.9 bits (151), Expect = 2e-09
Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 1/126 (0%)
Frame = +2
Query: 230 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNS 409
N F++AEAG NH G GA +KFQ T + Y N
Sbjct: 13 NWVFVVAEAGVNHNGSIERALDMVEAAARAGADAIKFQTFRAAGLVTANAEKAAYQKRND 72
Query: 410 WGKT-YGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 586
T E S LE S++Q+R + + VGI F ++ D S DFL +L V KI SG
Sbjct: 73 GIDTNQAEMLSALELSESQWRTIKDHCSMVGISFLSTPFDEDSADFLESLGVEAFKISSG 132
Query: 587 GLEQLA 604
L LA
Sbjct: 133 DLTHLA 138
>UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate
synthase; n=11; cellular organisms|Rep:
N-acetylneuraminic acid phosphate synthase -
Methanosarcina acetivorans
Length = 286
Score = 64.5 bits (150), Expect = 2e-09
Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 2/133 (1%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXX-GASCVKFQKTCLGXKFTKKYLERPYDNP-NSWG 415
+IAE G NH+G+ VKFQK T + P+ P NS+G
Sbjct: 6 VIAEIGCNHKGEMEIAHEMIKVAAQFCKVDIVKFQKRTPVELLTPEEYNAPHPVPHNSYG 65
Query: 416 KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGLE 595
KTYGEH+ LEF+ Q++ L + + G++++ S D+ + +V++ IKI S
Sbjct: 66 KTYGEHREFLEFNLDQHKQLKKWCDDWGVVYSTSVWDLTAAKEIVSINPELIKIPSACNL 125
Query: 596 QLALPKVRCFEKD 634
+ + + C E D
Sbjct: 126 KFDMLEYLCKEYD 138
>UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ1065 - Methanococcus jannaschii
Length = 337
Score = 64.1 bits (149), Expect = 3e-09
Identities = 43/136 (31%), Positives = 64/136 (47%)
Frame = +2
Query: 185 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXK 364
M ++KI D +G P FIIAE G NH GD GA +KFQ
Sbjct: 1 MEKIKIGDRY-VGKGEPTFIIAEGGLNHNGDIDIGKELVKEAKKCGADAIKFQSY----- 54
Query: 365 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDF 544
T+ ++ + + Y E LE S+ ++ L YA+++GI+F ++ +D+ D
Sbjct: 55 HTEDFISKKSE--------YYELFKSLELSEEEFYELKEYAEKIGIMFISTPLDLKYVDI 106
Query: 545 LVNLKVPFIKIGSGGL 592
L + VP KI SG L
Sbjct: 107 LNKMNVPAFKIASGDL 122
>UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Methanococcus
maripaludis
Length = 348
Score = 63.7 bits (148), Expect = 4e-09
Identities = 43/132 (32%), Positives = 58/132 (43%), Gaps = 2/132 (1%)
Frame = +2
Query: 224 GNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNP 403
G FIIAEAG NH G G VKFQ T+ + Y
Sbjct: 11 GLKNAFIIAEAGVNHNGSLELAKKLIDVAFEAGVDAVKFQTFKTENVVTENAEKAEYQIQ 70
Query: 404 NSWGKTYGEHK--SHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 577
N+ ++ +++ LE S+ + L+ Y QE GILF ++ D S DFL +L VP KI
Sbjct: 71 NTGVESESQYEMIKKLELSEKDFERLYNYCQEKGILFLSTPFDFESADFLDDL-VPLFKI 129
Query: 578 GSGGLEQLALPK 613
S L + K
Sbjct: 130 SSTDLNNIPFLK 141
>UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3;
cellular organisms|Rep: N-acetylneuraminate synthase -
Flavobacteriales bacterium HTCC2170
Length = 351
Score = 63.3 bits (147), Expect = 5e-09
Identities = 45/141 (31%), Positives = 58/141 (41%), Gaps = 1/141 (0%)
Frame = +2
Query: 185 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXK 364
M +KI +D I +PCFIIAEAG NH G G CVKFQ
Sbjct: 1 MKSIKI-EDFLISKESPCFIIAEAGVNHNGKLEMALELVRKAKEIGVDCVKFQTFTAESV 59
Query: 365 FTKKYLERPYD-NPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFD 541
TKK + Y ++ E LE S Y + + I F ++ + D
Sbjct: 60 ITKKAPKANYQLEVTDPAESQFEMLKKLELSGDDYIKIIEECNKQNITFLSTPYNEEDAD 119
Query: 542 FLVNLKVPFIKIGSGGLEQLA 604
FL L V KI SG + +LA
Sbjct: 120 FLNKLGVSAFKIASGQIVELA 140
>UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein,
putative; n=1; Geobacter sulfurreducens|Rep:
Polysaccharide biosynthesis protein, putative -
Geobacter sulfurreducens
Length = 350
Score = 62.1 bits (144), Expect = 1e-08
Identities = 41/138 (29%), Positives = 59/138 (42%), Gaps = 3/138 (2%)
Frame = +2
Query: 209 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLER 388
++ +G NP ++IAE G NH GD GA VKFQ ++ ER
Sbjct: 8 NVPVGAENPPYVIAEIGSNHNGDMNLCRQLIDAAAEAGAHAVKFQSWTENSLIAREEYER 67
Query: 389 --PY-DNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLK 559
Y D +G K++ + + Q+R Y +E GI F ++ D L +L
Sbjct: 68 NTEYSDKKRHFGSLRDMVKTY-QLTTDQHREAHAYCRERGIAFCSTPFSPEEADLLESLD 126
Query: 560 VPFIKIGSGGLEQLALPK 613
VPF KI S + L K
Sbjct: 127 VPFFKIASMDIVHLPFLK 144
>UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis
protein; n=1; Clostridium kluyveri DSM 555|Rep:
Predicted polysaccharide biosynthesis protein -
Clostridium kluyveri DSM 555
Length = 335
Score = 58.8 bits (136), Expect = 1e-07
Identities = 43/141 (30%), Positives = 61/141 (43%)
Frame = +2
Query: 185 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXK 364
M ++KI + I IG +PCFIIAEAG NH GD GA+ VKFQ
Sbjct: 1 MNDIKIGNKI-IGNTHPCFIIAEAGSNHNGDIKQAKELVDIAVEAGANAVKFQTFTADKL 59
Query: 365 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDF 544
F+K + N K + EF ++ + Y + GI+F + + D
Sbjct: 60 FSKNH------PANKIVKNF-------EFKLEWHKEMKEYCDKKGIMFITTPFQKDAVDL 106
Query: 545 LVNLKVPFIKIGSGGLEQLAL 607
L L + KI SG ++ L
Sbjct: 107 LEKLNIEGYKIASGDMDYYPL 127
>UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid
synthetase; n=4; Leptospira|Rep: N-acetyl neuraminic
(Sialic) acid synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 332
Score = 58.4 bits (135), Expect = 1e-07
Identities = 38/136 (27%), Positives = 64/136 (47%)
Frame = +2
Query: 200 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKY 379
I ++ +G +P ++AE G NH D GA VKFQ T+++
Sbjct: 9 IASELYVGSESPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQVVKFQSYV-----TEEF 63
Query: 380 LERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLK 559
++ NP++ K + E S+T +R A++ G+ F ++ + + S L++LK
Sbjct: 64 ID--VHNPDA--KILVDIFKKYELSETMHRKFQKTAEDEGLFFFSTPLCVNSLHLLLSLK 119
Query: 560 VPFIKIGSGGLEQLAL 607
VP IKI SG + L
Sbjct: 120 VPAIKIASGDITNKTL 135
>UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1;
Clostridium tetani|Rep: N-acetylneuraminate synthase -
Clostridium tetani
Length = 351
Score = 58.0 bits (134), Expect = 2e-07
Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
+IG N P +I+AE G NH GD G VKFQ +T K L
Sbjct: 11 KIGENYPAYIVAEIGANHNGDVNLAKRMIEVAAECGVDAVKFQ------TYTAKELVSDT 64
Query: 395 DNPNSWG-------KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVN 553
D +WG +T G+ + ++ +F YA ++G++ ++ + +FL
Sbjct: 65 DRILTWGPCGKQKTETIGKMFDRIALPREAHKEVFEYANKLGLMAFSTPFSIKGVEFLNE 124
Query: 554 LKVPFIKIGSGGLEQLALPK 613
L+VP K+ + ++ L + K
Sbjct: 125 LEVPCFKVAASDVDYLDILK 144
>UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides
thetaiotaomicron|Rep: Sialic acid synthase - Bacteroides
thetaiotaomicron
Length = 346
Score = 56.4 bits (130), Expect = 6e-07
Identities = 37/134 (27%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXX-----------XXGASCVKFQKTCLGXKFTKKYLE 385
+II E GQNH G + VK K L + +
Sbjct: 5 YIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMN 64
Query: 386 RPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVP 565
+ YDNPNS+G+TYGEH++ LE D + ++ YA+ +G+ F + L
Sbjct: 65 QIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPD 124
Query: 566 FIKIGSGGLEQLAL 607
+K+ S L L L
Sbjct: 125 RLKVASRDLTNLPL 138
>UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9303|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9303)
Length = 335
Score = 56.4 bits (130), Expect = 6e-07
Identities = 34/124 (27%), Positives = 54/124 (43%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGKT 421
IIAEAG NH G+ GA +KFQ + + Y + T
Sbjct: 5 IIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRST 64
Query: 422 YGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGLEQL 601
E + LE ++ +++ + Y +++ I F ++A D L+ LKV IK+ SG +
Sbjct: 65 QREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHW 124
Query: 602 ALPK 613
L K
Sbjct: 125 PLLK 128
>UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Rep:
Blr5992 protein - Bradyrhizobium japonicum
Length = 356
Score = 56.0 bits (129), Expect = 7e-07
Identities = 45/127 (35%), Positives = 52/127 (40%), Gaps = 5/127 (3%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ----KTCLGXKFTKK-YLERPYDNPN 406
IIAEAG NH G GA VKFQ K G K Y +R D
Sbjct: 7 IIAEAGVNHDGSLEKALALVDAAADAGADIVKFQTFNAKALAGGAAKKADYQQRTTDAAE 66
Query: 407 SWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 586
S LE + L A E GI F ++ D S FL++LK+P IKIGSG
Sbjct: 67 SQLAML----ERLELPQAAHHTLIERAAERGIEFLSTPFDDASLGFLLSLKLPRIKIGSG 122
Query: 587 GLEQLAL 607
L L
Sbjct: 123 DLTNAPL 129
>UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3;
Proteobacteria|Rep: Sialic acid synthase - Vibrio
vulnificus (strain YJ016)
Length = 357
Score = 55.6 bits (128), Expect = 1e-06
Identities = 41/124 (33%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGK- 418
IIAEAG NH GD GA VKFQ T++ + Y N+ +
Sbjct: 4 IIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQE 63
Query: 419 TYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGGLE 595
+ S LE S + L + + +GI F ++A D S DFLVN L + +K+ SG L
Sbjct: 64 SQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELT 123
Query: 596 QLAL 607
L
Sbjct: 124 NAPL 127
>UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=17; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Synechococcus sp. (strain CC9902)
Length = 762
Score = 55.6 bits (128), Expect = 1e-06
Identities = 35/131 (26%), Positives = 51/131 (38%), Gaps = 1/131 (0%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYD 397
IG +PCF+IAE G NH GD GA C KFQ +G ++ + D
Sbjct: 128 IGAEHPCFVIAEIGNNHNGDINTALQLIDAAHAAGADCAKFQMRDMGQLYSNS--GKSSD 185
Query: 398 NPNSWGKTYG-EHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 574
+ G Y + + SD + F Y+ G++ + D S L + K
Sbjct: 186 MASDLGTQYTLDLLERFQLSDDELFHCFDYSASKGLVPLCTPWDQTSLQKLNQWGMEGFK 245
Query: 575 IGSGGLEQLAL 607
+ S AL
Sbjct: 246 VASADFTNHAL 256
>UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 357
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/125 (33%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGKT 421
IIAEAG NH GD GA VKFQ T+K + Y N G+
Sbjct: 4 IIAEAGVNHNGDAKLARDLVTSAHKAGADIVKFQTFKAKNIVTEKATQANYQKKN-LGRE 62
Query: 422 YGE--HKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGGL 592
+ LE S + L Y E+GI F ++A D S +FLVN L + +K+ SG +
Sbjct: 63 ESQLAMLQRLELSHELHYELVDYCNELGIEFLSTAFDDESLNFLVNDLGLKRLKLPSGEI 122
Query: 593 EQLAL 607
L
Sbjct: 123 TNAPL 127
>UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzyme;
n=1; Synechococcus sp. CC9311|Rep: N-acetylneuraminic
acid condensing enzyme - Synechococcus sp. (strain
CC9311)
Length = 347
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/126 (28%), Positives = 48/126 (38%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
RI +P +I+AE G NH G+ GA VKFQ + Y
Sbjct: 11 RISSIDPTYIVAEIGVNHNGNISLAHKLIDSAKDAGADAVKFQTYVTDELVIRNTRTAKY 70
Query: 395 DNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 574
N+ E S + L+ + GI F ++ D VS F+ NLK IK
Sbjct: 71 QKENALFDDQYTMLEKYELSFESFHELYRHCAAAGIDFLSTPFDPVSLRFIANLKPVAIK 130
Query: 575 IGSGGL 592
SG L
Sbjct: 131 WASGEL 136
>UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep:
Sialic acid synthase - Vibrio vulnificus
Length = 333
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/123 (35%), Positives = 52/123 (42%), Gaps = 2/123 (1%)
Frame = +2
Query: 230 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ--KTCLGXKFTKKYLERPYDNP 403
N FIIAEAG NH GD G VKFQ KT L K E +N
Sbjct: 3 NKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVENT 62
Query: 404 NSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 583
+T E LE S + L Y + GI F ++ + S FL L+ F KIGS
Sbjct: 63 QR-EETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVF-KIGS 120
Query: 584 GGL 592
G L
Sbjct: 121 GEL 123
>UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
N-acylneuraminate-9-phosphate synthase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 348
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/136 (28%), Positives = 59/136 (43%)
Frame = +2
Query: 185 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXK 364
M E+ I D IG N+P ++IAEAG +H GA +KFQ T +
Sbjct: 1 MTELHI-DGRAIGPNHPPYVIAEAGVHHYDSLELARAYVLEARKAGADAIKFQ-TYTADE 58
Query: 365 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDF 544
++ Y + + + S T+YR LF YA+E+GI ++ D S D
Sbjct: 59 LVTRWAPL-YWTDARFETQHQVFSTKRGLSPTEYRSLFDYARELGITPLSTPFDPASVDL 117
Query: 545 LVNLKVPFIKIGSGGL 592
L L + K+ S +
Sbjct: 118 LDGLGMAAFKVASADI 133
>UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis
protein SiaC; n=3; Bacteria|Rep: Polysialic acid capsule
biosynthesis protein SiaC - Loktanella vestfoldensis
SKA53
Length = 343
Score = 53.6 bits (123), Expect = 4e-06
Identities = 37/131 (28%), Positives = 57/131 (43%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
+IG +P +IAE G NH GD G VK Q + + T++ R
Sbjct: 7 KIGPEHPPLVIAEIGINHGGDLAVAKEMVRLAALSGCEMVKHQTHIIADEMTEE--ARQI 64
Query: 395 DNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 574
PN+ + E S + L Y + +G+++ ++ + DFL +L VP K
Sbjct: 65 FPPNA-DVSIWEVMEACALSLDEEAELKRYTESLGMIWISTPFSRAAADFLQDLDVPAFK 123
Query: 575 IGSGGLEQLAL 607
IGSG + L L
Sbjct: 124 IGSGEADNLPL 134
>UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2;
Gammaproteobacteria|Rep: Sialic acid synthase - Vibrio
shilonii AK1
Length = 751
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 1/140 (0%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
+IG P FIIAE G NH G GA CVKFQ + + + +
Sbjct: 123 KIGDQEPSFIIAEIGNNHNGSLELAKELVDLAKAAGADCVKFQMRDMASMYNNEGDDD-- 180
Query: 395 DNPNSWGKTYG-EHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFI 571
D G Y + + D ++ +F Y ++ IL + D S D L + V
Sbjct: 181 DASQDLGAQYVLDLLKRFQLCDEEFVEIFEYCKQKEILALCTPFDEASADKLEKIGVAGF 240
Query: 572 KIGSGGLEQLALPKVRCFEK 631
K+ S L L K +K
Sbjct: 241 KVASADLTNHRLLKYLAAKK 260
>UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7;
Proteobacteria|Rep: N-acetylneuraminic acid synthase -
Chromobacterium violaceum
Length = 361
Score = 52.0 bits (119), Expect = 1e-05
Identities = 38/123 (30%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Frame = +2
Query: 230 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNS 409
N FIIAEAG NH G GA VKFQ G + + Y +
Sbjct: 2 NHVFIIAEAGVNHNGSLKVALELIDAAKEAGADAVKFQTFKSGAVISMDAPKAEYQKTTT 61
Query: 410 -WGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLV-NLKVPFIKIGS 583
++ + LE S + L + ++ GILF ++ D+ S + LV L VP +K+ S
Sbjct: 62 GTSESQLDMVRKLELSAEDHIQLLQHCEKRGILFLSTPFDVQSAELLVRELGVPQLKVPS 121
Query: 584 GGL 592
G L
Sbjct: 122 GEL 124
>UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: N-acetylneuraminic acid (Sialic acid)
synthetase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 282
Score = 51.6 bits (118), Expect = 2e-05
Identities = 39/125 (31%), Positives = 57/125 (45%)
Frame = +2
Query: 209 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLER 388
+I+IGGNNP FIIAEAG NH GD A+ +KFQ + + ER
Sbjct: 9 NIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQ------AYNSE--ER 60
Query: 389 PYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPF 568
+N + EF ++ L +Q+ ILF A+ D+ + + L + V
Sbjct: 61 FGENKEAVNLV-----KPAEFGKKEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEI 115
Query: 569 IKIGS 583
+KI S
Sbjct: 116 LKIAS 120
>UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9301|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9301)
Length = 341
Score = 51.6 bits (118), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ--KTCLGXKFTKKYLERPYDNPNSWG 415
+IAEAG NH G GA +KFQ K+ F+ + Y ++
Sbjct: 5 VIAEAGVNHNGSLDLALKLVEEAKLSGADSIKFQTFKSESLASFSAPLAQ--YQKKSNSY 62
Query: 416 KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGLE 595
K+ + LE +D + +F + E+GI F +S + FL++L + IKI SG +
Sbjct: 63 KSQIDMLKSLELTDKDTKRIFSFCNEIGIEFMSSPFGVDELHFLLDLGMLSIKIPSGEIT 122
Query: 596 QLAL 607
AL
Sbjct: 123 NYAL 126
>UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr5971 protein - Bradyrhizobium
japonicum
Length = 641
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/130 (26%), Positives = 48/130 (36%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYD 397
+G PC++IAE G NH GD GA C KFQ L + L D
Sbjct: 19 LGDGEPCYVIAEVGNNHNGDFDRAIALVDAAVAAGADCAKFQMRKLDEVYRASSLSGK-D 77
Query: 398 NPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 577
+ + T + E + Q + + Y GI + + D S L V K+
Sbjct: 78 DDLAVEYTL-DLLRRFELTTEQQKKIADYCASKGIQYLCTPWDAKSVAVLEGFGVQAYKV 136
Query: 578 GSGGLEQLAL 607
S L L L
Sbjct: 137 ASADLTNLPL 146
>UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1;
Enterococcus faecium DO|Rep: N-acetylneuraminate
synthase - Enterococcus faecium DO
Length = 335
Score = 49.6 bits (113), Expect = 6e-05
Identities = 37/122 (30%), Positives = 49/122 (40%), Gaps = 1/122 (0%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPN-SWG 415
++IAE G NH G GA+ VKFQ +KK Y N
Sbjct: 7 YVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKTNKLVSKKAPMAKYQKDNLKED 66
Query: 416 KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGLE 595
+ E LE S + + + Y + I F ++ D S DFL + V KIGSG L
Sbjct: 67 SSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFDEESADFLKQIGVQGFKIGSGDLT 126
Query: 596 QL 601
L
Sbjct: 127 NL 128
>UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Alphaproteobacteria|Rep:
N-acylneuraminate-9-phosphate synthase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 350
Score = 49.6 bits (113), Expect = 6e-05
Identities = 35/116 (30%), Positives = 45/116 (38%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGK 418
F+IAEAG NH G GA VKFQ T + Y +
Sbjct: 12 FVIAEAGVNHDGSLDKALRLVDIAVEAGADAVKFQTFRTDEVVTPDAAKAAYQQRQTGAG 71
Query: 419 TYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 586
T E LE D + L + E GI F ++ + D L+ L + IKI SG
Sbjct: 72 TQYEMIRALELDDAAHERLARHCAERGIEFMSTPFAPWAVDMLLGLGMRRIKIASG 127
>UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1;
Magnetospirillum gryphiswaldense|Rep:
N-acetylneuraminate synthase - Magnetospirillum
gryphiswaldense
Length = 354
Score = 49.6 bits (113), Expect = 6e-05
Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWG-K 418
IIAEAG NH G GA VKFQ + Y N G +
Sbjct: 5 IIAEAGVNHDGKIDQALRLIDAAAAAGADVVKFQTFKAAALASAVAGRAEYQIRNLGGTE 64
Query: 419 TYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGGL 592
+ + LE S+ + L + ++ GI F +S D +S +FL++ L + IK+GSG L
Sbjct: 65 SQLDMLRRLELSEDDHFRLRDHCRQAGIGFLSSPFDRLSLEFLIDRLGLDTIKLGSGEL 123
>UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=6; Bacteria|Rep: N-acetylneuraminic acid
(Sialic acid) synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 364
Score = 48.8 bits (111), Expect = 1e-04
Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 3/141 (2%)
Frame = +2
Query: 194 VKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ---KTCLGXK 364
+++ + I G +P ++IAE G NH+G GA KFQ L K
Sbjct: 15 IQLGNKIIAGFFDP-YVIAEIGVNHEGSIDIAKRLIDEAKDGGADGAKFQTYKAETLASK 73
Query: 365 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDF 544
+ Y +R + S + + ++ S F +Y L + Q VGI F ++ D+ + +
Sbjct: 74 NSPSYWDRTQEPTASQFELFKKYDS---FGWKEYEILAKHCQSVGIDFLSTPFDLEAVEH 130
Query: 545 LVNLKVPFIKIGSGGLEQLAL 607
L + ++PFIK+ S + + L
Sbjct: 131 LAS-QMPFIKVASADITSVPL 150
>UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Desulfovibrio desulfuricans G20|Rep:
N-acylneuraminate-9-phosphate synthase - Desulfovibrio
desulfuricans (strain G20)
Length = 344
Score = 48.4 bits (110), Expect = 1e-04
Identities = 42/134 (31%), Positives = 51/134 (38%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYD 397
I NP F+IAE G NH+GD GA VK Q G + +E P
Sbjct: 5 ISDKNPVFVIAEIGGNHEGDFAYARKLVSLAIESGADAVKLQ-VYAGDALVSR-VESPDR 62
Query: 398 NPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 577
N H E S QY L + G+ F ASA D + + V K
Sbjct: 63 N---------RHFKKFELSRGQYEALIDMCRHAGVQFMASAWDRERLGW-IEPHVRIHKA 112
Query: 578 GSGGLEQLALPKVR 619
GSG L A P +R
Sbjct: 113 GSGDL--TAYPMLR 124
>UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=29; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Shewanella sp.
(strain W3-18-1)
Length = 349
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/136 (26%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Frame = +2
Query: 188 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKF 367
++V D IG P F+IAE NH GAS +K Q T
Sbjct: 1 MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQ-TYTPDTI 59
Query: 368 TKKYLERPY---DNPNSW-GKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVS 535
T + D N W G++ + S ++ LF YA+ +G++ ++ D+ +
Sbjct: 60 TLNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTA 119
Query: 536 FDFLVNLKVPFIKIGS 583
++L L VP KI S
Sbjct: 120 VEYLEKLNVPCYKIAS 135
>UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellular
organisms|Rep: NeuNAc condensing enzyme - Escherichia
coli
Length = 350
Score = 46.4 bits (105), Expect = 6e-04
Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 2/123 (1%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWG- 415
+I+AE G NH GD G VKFQ T + KY + G
Sbjct: 9 YIVAEIGCNHNGDFELAKKMVKEAKSAGVDAVKFQ-TFKAEQLISKYAPKAEYQIKVTGN 67
Query: 416 -KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGL 592
+T E LE ++ L YA+E+G+ ++ D S DFL + KI SG L
Sbjct: 68 EETQLEMTRKLELPYDEFIKLEEYAKELGLDVFSTPFDFDSIDFLASRNQKVWKIPSGEL 127
Query: 593 EQL 601
L
Sbjct: 128 LNL 130
>UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB -
Escherichia coli
Length = 346
Score = 45.2 bits (102), Expect = 0.001
Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 2/123 (1%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWG- 415
+I+AE G NH GD G VKFQ T + KY + G
Sbjct: 5 YIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQ-TFKADQLISKYAPKAEYQIKVTGN 63
Query: 416 -KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGL 592
++ E LE ++ L YA+E+G+ ++ D S DFL + KI SG L
Sbjct: 64 QESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGEL 123
Query: 593 EQL 601
L
Sbjct: 124 LNL 126
>UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG2089:
Sialic acid synthase - Magnetospirillum magnetotacticum
MS-1
Length = 346
Score = 44.8 bits (101), Expect = 0.002
Identities = 42/121 (34%), Positives = 51/121 (42%), Gaps = 6/121 (4%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLG---XKFTKK--YLERPYDNP 403
FIIAEAG NH GD A VKFQ G +F K YLE +
Sbjct: 14 FIIAEAGVNHDGDIQRAKRLIDVAAEAQADAVKFQTWRPGEITGRFAYKVNYLEATTEQA 73
Query: 404 NSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLV-NLKVPFIKIG 580
S Y E L +R L + + GILF ++ S FLV L +P +KIG
Sbjct: 74 ES---RY-ELSCRLALPYPVFRELKSHCEARGILFLSTPDGFDSLAFLVGELDMPIVKIG 129
Query: 581 S 583
S
Sbjct: 130 S 130
>UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium
botulinum F str. Langeland|Rep: NeuB family protein -
Clostridium botulinum (strain Langeland / NCTC 10281 /
Type F)
Length = 343
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/133 (27%), Positives = 50/133 (37%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
++G + FIIAE G NH G+ GA VKFQ + +K Y
Sbjct: 10 KVGEKSSIFIIAEIGVNHNGNIDLAYKLIDLASKAGADAVKFQMF-----YPEKLCSEIY 64
Query: 395 DNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 574
K E S + L Y +G+ F + D S D ++NL IK
Sbjct: 65 R------KDEIEMLKKYVLSFENMKKLRDYTYSLGLEFIVTPFDFKSLDDIINLDCSAIK 118
Query: 575 IGSGGLEQLALPK 613
+ SG L + K
Sbjct: 119 VASGELTHIPFIK 131
>UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis
protein spsE; n=2; Bacillus|Rep: Spore coat
polysaccharide biosynthesis protein spsE - Bacillus
subtilis
Length = 373
Score = 43.2 bits (97), Expect = 0.006
Identities = 37/134 (27%), Positives = 51/134 (38%), Gaps = 2/134 (1%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYD 397
+G + P FIIAEAG NH G GA VKFQ + + Y + P
Sbjct: 11 VGKDAPVFIIAEAGINHDGKLDQAFALIDAAAEAGADAVKFQM----FQADRMYQKDPGL 66
Query: 398 NPNSWGKTYGEHK--SHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFI 571
+ GK +E L Y +E ++F ++ D S D L +
Sbjct: 67 YKTAAGKDVSIFSLVQSMEMPAEWILPLLDYCREKQVIFLSTVCDEGSADLLQSTSPSAF 126
Query: 572 KIGSGGLEQLALPK 613
KI S + L L K
Sbjct: 127 KIASYEINHLPLLK 140
>UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1;
Gramella forsetii KT0803|Rep: N-acetylneuraminate
synthase - Gramella forsetii (strain KT0803)
Length = 332
Score = 42.3 bits (95), Expect = 0.010
Identities = 31/122 (25%), Positives = 48/122 (39%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGKT 421
+IAE GQ H+G G VKFQ + LE + KT
Sbjct: 3 VIAEVGQAHEGSLGMALSYIGALAEAGVDAVKFQVHI--AEAESSILEPFRIKFSEQDKT 60
Query: 422 YGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGLEQL 601
++ +EFS +++ + ++ + F AS + D L + V KIGSG +
Sbjct: 61 RFDYWKRMEFSTDEWKLIKKTCEDNNVEFLASPFSNAAVDLLEEVGVKRYKIGSGEVNNF 120
Query: 602 AL 607
L
Sbjct: 121 LL 122
>UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular
organisms|Rep: NeuB family member - uncultured archaeon
Length = 360
Score = 41.9 bits (94), Expect = 0.013
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Frame = +2
Query: 239 FIIAEAGQNH-----QGDXX---XXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
FI+AEAG N+ +G+ GA +KFQ T + KY +
Sbjct: 19 FIVAEAGVNYYDIAKKGNIEPLEAAKLMIEKAADSGADAIKFQ-TYKAERIASKYSPAYW 77
Query: 395 DNPNSWGKT-YGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFI 571
D K+ Y K +F + +Y+ L YA ILF ++ D + DFL L +P
Sbjct: 78 DVTKENTKSQYELFKKFDKFGEDEYKELAGYAANTDILFMSTPFDNEAVDFLDKL-MPVF 136
Query: 572 KIGSGGLEQL 601
KI S + +
Sbjct: 137 KISSSDITNI 146
>UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema
denticola|Rep: NeuB family protein - Treponema denticola
Length = 379
Score = 41.5 bits (93), Expect = 0.017
Identities = 40/128 (31%), Positives = 49/128 (38%)
Frame = +2
Query: 230 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNS 409
NP IAE G +H G GA VKFQ D P
Sbjct: 19 NP-LTIAEIGTSHNGSIQKARNLIDVAAEAGAKAVKFQIVYADEILHPN--TGYVDLPTG 75
Query: 410 WGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGG 589
Y KS LE + Y+ L Y++ +LF+AS S + L LK FIKI S
Sbjct: 76 KIPLYDRFKS-LELPVSFYKELAEYSRSKKLLFSASPFGFRSAEELAALKPDFIKIASPE 134
Query: 590 LEQLALPK 613
L + L K
Sbjct: 135 LNYVQLLK 142
>UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB
protein - Escherichia coli
Length = 346
Score = 41.5 bits (93), Expect = 0.017
Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 1/122 (0%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWG- 415
+I+AE G NH G G + VKFQ + + Y N+
Sbjct: 5 YIVAEIGCNHNGSVDIAREMILKAKEAGVNAVKFQTFKADKLISAIAPKAEYQIKNTGEL 64
Query: 416 KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGLE 595
++ E LE Y L YA + + ++ D S DFL +LK KI SG L
Sbjct: 65 ESQLEMTKKLEMKYDDYLHLMEYAVSLNLDVFSTPFDEDSIDFLASLKQKIWKIPSGELL 124
Query: 596 QL 601
L
Sbjct: 125 NL 126
>UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB -
Aeromonas hydrophila
Length = 345
Score = 40.7 bits (91), Expect = 0.030
Identities = 40/139 (28%), Positives = 59/139 (42%), Gaps = 5/139 (3%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYD 397
IG ++IAE NH G+ GAS VK Q T T K +RP
Sbjct: 8 IGPAQAPYVIAELSANHNGNLERALAIMTAAKAAGASAVKLQ-TYRPDTITLK-SDRPEF 65
Query: 398 NPNSWGKTYGEHKSH--LEFSDTQ---YRXLFXYAQEVGILFTASAMDMVSFDFLVNLKV 562
+ G + H + E++ T ++ LF +E+G+ +S D + D L +L
Sbjct: 66 QIH--GGLWDGHSLYDLYEWAHTPWEWHQALFAKGRELGLTVFSSPFDFSAVDLLESLDC 123
Query: 563 PFIKIGSGGLEQLALPKVR 619
P KI S E + LP +R
Sbjct: 124 PAYKIAS--FELVDLPLIR 140
>UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.
MED297|Rep: Sialic acid synthase - Reinekea sp. MED297
Length = 354
Score = 40.7 bits (91), Expect = 0.030
Identities = 35/125 (28%), Positives = 46/125 (36%)
Frame = +2
Query: 227 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPN 406
N+ F+IAEAG NH GD GA +KFQ T + Y
Sbjct: 3 NDSVFLIAEAGVNHNGDVELAKELIELAAAAGADAIKFQTFIPEALVTTTARKAGYQK-T 61
Query: 407 SWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 586
+ ++ L + L YA I F ++A + S L L V KI SG
Sbjct: 62 AHEESQLAMLQALALPLPVFDELKAYADSKAIEFMSTAFESESLALLSQLAVRRYKIPSG 121
Query: 587 GLEQL 601
L L
Sbjct: 122 ELTNL 126
>UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep:
NeuB:Antifreeze-like protein - Alteromonas macleodii
'Deep ecotype'
Length = 347
Score = 40.7 bits (91), Expect = 0.030
Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 2/138 (1%)
Frame = +2
Query: 206 DDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLE 385
D I + +IIAE NH GD G S +K Q T T L+
Sbjct: 4 DQTNINEAHKPYIIAELSANHGGDLSRAKESITKAAEVGVSAIKIQ-TYTPDTMTLDSLQ 62
Query: 386 RPY-DNPNSW-GKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLK 559
+ W G++ E + + LF +A+ G+ ++ D + D L +L
Sbjct: 63 DDFIVKDGLWAGRSLYELYTEAYTPYEWHEELFNHAKNCGVTIFSTPFDETAVDLLESLN 122
Query: 560 VPFIKIGSGGLEQLALPK 613
P KI S + L L K
Sbjct: 123 TPAYKIASFEIVDLPLVK 140
>UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas sp.
MED121|Rep: NeuB family protein - Marinomonas sp. MED121
Length = 347
Score = 40.3 bits (90), Expect = 0.039
Identities = 35/127 (27%), Positives = 50/127 (39%), Gaps = 4/127 (3%)
Frame = +2
Query: 239 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWGK 418
FIIAE NH D G +K Q T T +
Sbjct: 11 FIIAELSGNHNQDFALAKAMIEAAAKTGVDAIKLQ-TYTADSMTLNVRNEEFMVSAQGSL 69
Query: 419 TYGEHKSHL-EFSDTQY---RXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 586
G++ L + T Y + LF YA+ +G++ +S D+ + +FL +L VP KI S
Sbjct: 70 WEGDNLYDLYAKASTPYEWHQPLFDYAKSLGLVAFSSPFDINAVNFLESLDVPIYKIASF 129
Query: 587 GLEQLAL 607
L L L
Sbjct: 130 ELTDLPL 136
>UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular
organisms|Rep: Sialic acid synthase - Clostridium
acetobutylicum
Length = 350
Score = 39.5 bits (88), Expect = 0.068
Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 3/126 (2%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK-TCLGXKFTKKYLERP 391
+IG FIIAE NH D GA +K Q T F
Sbjct: 11 KIGEGQRTFIIAEMSANHNQDFDRAVEIIKAAKRSGADAIKLQTYTPDTITFDSDNEYFQ 70
Query: 392 YDNPNSWGKTYGEHKSHLE-FSDTQYR-XLFXYAQEVGILFTASAMDMVSFDFLVNLKVP 565
W T HK + E ++ Q++ L A+E G++ +S D S DFL ++VP
Sbjct: 71 IKQGTIWDGTT-LHKLYEEAYTPWQWQPKLKEIAEEEGLICFSSPFDNTSVDFLEKMEVP 129
Query: 566 FIKIGS 583
K+ S
Sbjct: 130 AYKVAS 135
>UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Synechococcus sp. CC9902|Rep:
N-acylneuraminate-9-phosphate synthase - Synechococcus
sp. (strain CC9902)
Length = 349
Score = 39.1 bits (87), Expect = 0.090
Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 8/135 (5%)
Frame = +2
Query: 227 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK-------TCLGXK-FTKKYL 382
+NP + IA+ G NH GA KFQ + LG K L
Sbjct: 7 DNPLYFIADIGANHDSSLKRAKALIKTAAESGADAAKFQNFFAHSIVSDLGFKQLPNSIL 66
Query: 383 ERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKV 562
+ S Y + LE+++ L Y +E GI + + D+ +FL N V
Sbjct: 67 SHQAEWTESVFDVYDKASLSLEWTE----ELHSYCKECGISYMTTPYDISILEFL-NQYV 121
Query: 563 PFIKIGSGGLEQLAL 607
KIGSG + L L
Sbjct: 122 ACWKIGSGDITWLDL 136
>UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4;
Bacteria|Rep: N-acetylneuraminate synthase -
Neptuniibacter caesariensis
Length = 363
Score = 39.1 bits (87), Expect = 0.090
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 3/134 (2%)
Frame = +2
Query: 200 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ---KTCLGXKFT 370
I + I ++P + IA+ NH GD GA KFQ + F
Sbjct: 11 IVNSHSISESDPTYFIADIAANHDGDLEKAKELIWLSAEAGADAAKFQHFKADTIVSDFG 70
Query: 371 KKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLV 550
K L + ++W K+ E + E L ++ I F S D D+ +
Sbjct: 71 FKSLGGQQSHQSTWEKSVYEVYADAEVDLNWTEELVNTCKQAEIDFFTSPYDFDLADY-I 129
Query: 551 NLKVPFIKIGSGGL 592
+ VP KIGSG +
Sbjct: 130 DQFVPAHKIGSGDI 143
>UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like
protein; n=1; Shewanella denitrificans OS217|Rep:
N-acetylneuraminic acid synthase-like protein -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 359
Score = 39.1 bits (87), Expect = 0.090
Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 3/144 (2%)
Frame = +2
Query: 185 MVEVKITDDIR-IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGX 361
M + IT D R IG +IIAE NH+G G +K Q T
Sbjct: 1 MFKASITIDGRHIGPEYQPYIIAELSGNHKGSLSQALAMIDAAAASGVDAIKIQ-TYTAN 59
Query: 362 KFTKKYLERPYD-NPNSW-GKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVS 535
T ++ + N W G+T + ++ LF +A++ + +S D+ +
Sbjct: 60 TITLQHDGPEFRINGGLWKGRTLFDLYEEAHTPWEWHKSLFEHAKKQNVTLFSSPFDLKA 119
Query: 536 FDFLVNLKVPFIKIGSGGLEQLAL 607
+ L + + P KI S + + L
Sbjct: 120 IELLESCECPAYKISSFEINDIGL 143
>UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2;
Flexibacteraceae|Rep: N-acetylneuraminic acid synthetase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 348
Score = 39.1 bits (87), Expect = 0.090
Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 4/137 (2%)
Frame = +2
Query: 218 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK-TCLGXKFTKKYLERPY 394
I N+ F+IAE NH GA +K Q T F E
Sbjct: 9 ISENHKPFVIAEMSGNHNQSLDRALAIVDAAAAAGAHALKLQTYTADTITFNGTSDEFII 68
Query: 395 DNPNSWGKTYGEHKSHLE-FSDTQYRX-LFXYAQEVGILFTASAMDMVSFDFLVNLKVPF 568
+ NS K H+ + + ++ ++ +F A+ G++ +S D + DFL +L VP
Sbjct: 69 KDENSIWKNQNLHQLYQQAYTPWEWHAPIFERAKSHGMIAFSSPFDTTAVDFLESLDVPC 128
Query: 569 IKIGS-GGLEQLALPKV 616
KI S + + L KV
Sbjct: 129 YKIASFENTDHILLKKV 145
>UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
N-acylneuraminate-9-phosphate synthase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 352
Score = 38.3 bits (85), Expect = 0.16
Identities = 28/117 (23%), Positives = 42/117 (35%), Gaps = 1/117 (0%)
Frame = +2
Query: 236 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPNSWG 415
C +I E G NH G +K Q+ + + Y G
Sbjct: 16 CIVIGEIGVNHNRQQDMLFRLIDEGIAAGLDVIKLQRFKAEQEIAMQAPAADYQKRAGAG 75
Query: 416 KTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGS 583
++ + LE D F Y ++ G+ F +A D S DFL + L +KI S
Sbjct: 76 ESQLQMARQLELPDAWLTQAFDYCRQRGVGFLCTAFDHGSVDFLADRLGCKTVKIPS 132
>UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17;
Bacteria|Rep: NeuB protein, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 356
Score = 37.1 bits (82), Expect = 0.36
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 5/140 (3%)
Frame = +2
Query: 215 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPY 394
+IG ++ ++I E NH G G +K Q T T ++RP
Sbjct: 18 KIGADHSPYVICELSGNHNGSLERCLAMVDAAADTGCDAIKIQ-TYTADTITLD-VDRPE 75
Query: 395 DNPNS--W-GKTYGE--HKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLK 559
+ W G+T E ++H F + +F A++ G+ +S D + D L +L
Sbjct: 76 FKIHGGLWDGRTLYELYEEAHTPFE--WHAAIFERARQRGVTIFSSPFDETAVDLLDSLG 133
Query: 560 VPFIKIGSGGLEQLALPKVR 619
P KI S E + LP ++
Sbjct: 134 APAFKIAS--FEAVDLPLIK 151
>UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris HaA2|Rep: N-acetylneuraminate
synthase - Rhodopseudomonas palustris (strain HaA2)
Length = 332
Score = 36.7 bits (81), Expect = 0.48
Identities = 35/127 (27%), Positives = 49/127 (38%)
Frame = +2
Query: 227 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGXKFTKKYLERPYDNPN 406
+NP +IIAE G H G GA VKFQ T + T P
Sbjct: 5 SNP-YIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQ-THIAEAETLPNAPSPSYFSA 62
Query: 407 SWGKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 586
Y + FS Q+R L A+ + F +S + + D L ++ V KI SG
Sbjct: 63 EPRTAYFKRTG---FSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSG 119
Query: 587 GLEQLAL 607
+ + L
Sbjct: 120 EVSNIPL 126
>UniRef50_Q9LN03 Cluster: T6D22.13; n=2; Arabidopsis thaliana|Rep:
T6D22.13 - Arabidopsis thaliana (Mouse-ear cress)
Length = 641
Score = 35.9 bits (79), Expect = 0.84
Identities = 18/32 (56%), Positives = 21/32 (65%)
Frame = +2
Query: 539 DFLVNLKVPFIKIGSGGLEQLALPKVRCFEKD 634
DFLV L++P GSG E L+L KVRC KD
Sbjct: 439 DFLVLLEIPCCDNGSGESESLSLLKVRCVYKD 470
>UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. AS9601|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain AS9601)
Length = 356
Score = 35.5 bits (78), Expect = 1.1
Identities = 25/108 (23%), Positives = 45/108 (41%), Gaps = 3/108 (2%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ---KTCLGXKFTKKYLERPYDNPNSW 412
IIAE G NH GD G VKFQ + K +K Y + + S
Sbjct: 23 IIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTMSQ 82
Query: 413 GKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNL 556
+ + ++ +F +++ + Y + +LF ++ D S +++ L
Sbjct: 83 FELFSKYD---KFGLEEFKKIEDYCKRKSVLFMSTPFDSYSANYINQL 127
>UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1;
Maricaulis maris MCS10|Rep: N-acetylneuraminate synthase
- Maricaulis maris (strain MCS10)
Length = 305
Score = 35.1 bits (77), Expect = 1.5
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 3/120 (2%)
Frame = +2
Query: 242 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ---KTCLGXKFTKKYLERPYDNPNSW 412
+IAE G NH GD GA VKFQ + L +F K +NP
Sbjct: 6 VIAEIGSNHGGDLDQAKRYIEASAKAGADVVKFQTLTREGLIARFVKGADGTVTENPKF- 64
Query: 413 GKTYGEHKSHLEFSDTQYRXLFXYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGGL 592
+G + D + L A + G+ F ++ + + + + +L V KI SG L
Sbjct: 65 -AAFG----NAGLPDDWHAPLMTCAADNGVEFMSTPFSLDAVELMESLGVKRYKIASGDL 119
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 611,072,837
Number of Sequences: 1657284
Number of extensions: 11225419
Number of successful extensions: 25282
Number of sequences better than 10.0: 65
Number of HSP's better than 10.0 without gapping: 24591
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 25252
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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