Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P02_F_I11
(654 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein. 99 1e-20
AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine ... 99 1e-20
AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine ... 99 1e-20
U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein. 98 3e-20
BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein. 98 3e-20
AY049784-1|AAL15441.1| 948|Homo sapiens nardilysin protein. 98 3e-20
X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein. 83 8e-16
AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform prot... 83 8e-16
AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine ... 83 8e-16
AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine ... 83 8e-16
M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme ... 64 5e-10
BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzym... 64 5e-10
BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzym... 64 5e-10
BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzym... 64 5e-10
AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzym... 64 5e-10
AL356128-1|CAI13669.1| 257|Homo sapiens insulin-degrading enzym... 64 5e-10
AF061243-1|AAC67244.1| 1038|Homo sapiens metalloprotease 1 protein. 31 2.7
U80669-1|AAB38747.1| 234|Homo sapiens androgen regulated homeob... 30 8.3
>X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein.
Length = 1151
Score = 99.1 bits (236), Expect = 1e-20
Identities = 63/161 (39%), Positives = 79/161 (49%), Gaps = 25/161 (15%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D + D
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDS 160
Query: 426 GKSVQSATS----------DHHGT---TXRNDFDEX------------KLXACALCVGVG 530
G ++ D H T N+ +E K A ALCVGVG
Sbjct: 161 GAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVG 220
Query: 531 SYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
S++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 221 SFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 261
>AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1151
Score = 99.1 bits (236), Expect = 1e-20
Identities = 63/161 (39%), Positives = 79/161 (49%), Gaps = 25/161 (15%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D + D
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDS 160
Query: 426 GKSVQSATS----------DHHGT---TXRNDFDEX------------KLXACALCVGVG 530
G ++ D H T N+ +E K A ALCVGVG
Sbjct: 161 GAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVG 220
Query: 531 SYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
S++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 221 SFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 261
>AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1151
Score = 99.1 bits (236), Expect = 1e-20
Identities = 63/161 (39%), Positives = 79/161 (49%), Gaps = 25/161 (15%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D + D
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDS 160
Query: 426 GKSVQSATS----------DHHGT---TXRNDFDEX------------KLXACALCVGVG 530
G ++ D H T N+ +E K A ALCVGVG
Sbjct: 161 GAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVG 220
Query: 531 SYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
S++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 221 SFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 261
>U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein.
Length = 1147
Score = 97.9 bits (233), Expect = 3e-20
Identities = 64/160 (40%), Positives = 78/160 (48%), Gaps = 24/160 (15%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D E G
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEDDDEDSG 160
Query: 426 ---------GKSVQSATSDHHGT---TXRNDFDEX------------KLXACALCVGVGS 533
G + D H T N+ +E K A ALCVGVGS
Sbjct: 161 AEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGS 220
Query: 534 YSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 221 FADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 260
>BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein.
Length = 1150
Score = 97.9 bits (233), Expect = 3e-20
Identities = 64/160 (40%), Positives = 78/160 (48%), Gaps = 24/160 (15%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D E G
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEDDDEDSG 160
Query: 426 ---------GKSVQSATSDHHGT---TXRNDFDEX------------KLXACALCVGVGS 533
G + D H T N+ +E K A ALCVGVGS
Sbjct: 161 AEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGS 220
Query: 534 YSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 221 FADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 260
>AY049784-1|AAL15441.1| 948|Homo sapiens nardilysin protein.
Length = 948
Score = 97.9 bits (233), Expect = 3e-20
Identities = 64/160 (40%), Positives = 78/160 (48%), Gaps = 24/160 (15%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D E G
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEGEVEEEEDDDEDSG 160
Query: 426 ---------GKSVQSATSDHHGT---TXRNDFDEX------------KLXACALCVGVGS 533
G + D H T N+ +E K A ALCVGVGS
Sbjct: 161 AEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGS 220
Query: 534 YSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 221 FADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 260
>X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein.
Length = 1219
Score = 83.0 bits (196), Expect = 8e-16
Identities = 36/52 (69%), Positives = 42/52 (80%)
Frame = +3
Query: 498 LXACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
L A ALCVGVGS++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 278 LSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 329
Score = 46.4 bits (105), Expect = 9e-05
Identities = 26/82 (31%), Positives = 37/82 (45%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D + D
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDS 160
Query: 426 GKSVQSATSDHHGTTXRNDFDE 491
G ++ D G ++FD+
Sbjct: 161 GAEIED--DDEEGFDDEDEFDD 180
>AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform
protein.
Length = 1086
Score = 83.0 bits (196), Expect = 8e-16
Identities = 36/52 (69%), Positives = 42/52 (80%)
Frame = +3
Query: 498 LXACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
L A ALCVGVGS++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 145 LSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 196
>AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1219
Score = 83.0 bits (196), Expect = 8e-16
Identities = 36/52 (69%), Positives = 42/52 (80%)
Frame = +3
Query: 498 LXACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
L A ALCVGVGS++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 278 LSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 329
Score = 46.4 bits (105), Expect = 9e-05
Identities = 26/82 (31%), Positives = 37/82 (45%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D + D
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDS 160
Query: 426 GKSVQSATSDHHGTTXRNDFDE 491
G ++ D G ++FD+
Sbjct: 161 GAEIED--DDEEGFDDEDEFDD 180
>AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1219
Score = 83.0 bits (196), Expect = 8e-16
Identities = 36/52 (69%), Positives = 42/52 (80%)
Frame = +3
Query: 498 LXACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
L A ALCVGVGS++DP ++ GLAHF+ HMVFMGS KYP EN FDAF+ K GG
Sbjct: 278 LSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGG 329
Score = 46.4 bits (105), Expect = 9e-05
Identities = 26/82 (31%), Positives = 37/82 (45%)
Frame = +3
Query: 246 PEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESDG 425
PE +KS +D K Y+ I+L NGL ALLISD S + D + D
Sbjct: 101 PEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDS 160
Query: 426 GKSVQSATSDHHGTTXRNDFDE 491
G ++ D G ++FD+
Sbjct: 161 GAEIED--DDEEGFDDEDEFDD 180
>M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 63.7 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 36/50 (72%)
Frame = +3
Query: 504 ACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
+ AL V +GS SDP I GL+HF HM+F+G++KYPKENE+ F+ + G
Sbjct: 87 SAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAG 136
Score = 32.3 bits (70), Expect = 1.6
Identities = 13/27 (48%), Positives = 19/27 (70%)
Frame = +3
Query: 258 KSEADKKLYKTIRLXNGLTALLISDPS 338
KS DK+ Y+ + L NG+ LL+SDP+
Sbjct: 56 KSPEDKREYRGLELANGIKVLLMSDPT 82
>BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 63.7 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 36/50 (72%)
Frame = +3
Query: 504 ACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
+ AL V +GS SDP I GL+HF HM+F+G++KYPKENE+ F+ + G
Sbjct: 87 SAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAG 136
Score = 33.5 bits (73), Expect = 0.67
Identities = 14/27 (51%), Positives = 19/27 (70%)
Frame = +3
Query: 258 KSEADKKLYKTIRLXNGLTALLISDPS 338
KS DK+ Y+ + L NG+ LLISDP+
Sbjct: 56 KSPEDKREYRGLELANGIKVLLISDPT 82
>BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 63.7 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 36/50 (72%)
Frame = +3
Query: 504 ACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
+ AL V +GS SDP I GL+HF HM+F+G++KYPKENE+ F+ + G
Sbjct: 87 SAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAG 136
Score = 33.5 bits (73), Expect = 0.67
Identities = 14/27 (51%), Positives = 19/27 (70%)
Frame = +3
Query: 258 KSEADKKLYKTIRLXNGLTALLISDPS 338
KS DK+ Y+ + L NG+ LLISDP+
Sbjct: 56 KSPEDKREYRGLELANGIKVLLISDPT 82
>BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 63.7 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 36/50 (72%)
Frame = +3
Query: 504 ACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
+ AL V +GS SDP I GL+HF HM+F+G++KYPKENE+ F+ + G
Sbjct: 87 SAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAG 136
Score = 33.5 bits (73), Expect = 0.67
Identities = 14/27 (51%), Positives = 19/27 (70%)
Frame = +3
Query: 258 KSEADKKLYKTIRLXNGLTALLISDPS 338
KS DK+ Y+ + L NG+ LLISDP+
Sbjct: 56 KSPEDKREYRGLELANGIKVLLISDPT 82
>AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 63.7 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 36/50 (72%)
Frame = +3
Query: 504 ACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
+ AL V +GS SDP I GL+HF HM+F+G++KYPKENE+ F+ + G
Sbjct: 87 SAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAG 136
Score = 33.5 bits (73), Expect = 0.67
Identities = 14/27 (51%), Positives = 19/27 (70%)
Frame = +3
Query: 258 KSEADKKLYKTIRLXNGLTALLISDPS 338
KS DK+ Y+ + L NG+ LLISDP+
Sbjct: 56 KSPEDKREYRGLELANGIKVLLISDPT 82
>AL356128-1|CAI13669.1| 257|Homo sapiens insulin-degrading enzyme
protein.
Length = 257
Score = 63.7 bits (148), Expect = 5e-10
Identities = 26/50 (52%), Positives = 36/50 (72%)
Frame = +3
Query: 504 ACALCVGVGSYSDPAEIQGLAHFVXHMVFMGSEKYPKENEFDAFIXKXGG 653
+ AL V +GS SDP I GL+HF HM+F+G++KYPKENE+ F+ + G
Sbjct: 73 SAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAG 122
Score = 33.5 bits (73), Expect = 0.67
Identities = 14/27 (51%), Positives = 19/27 (70%)
Frame = +3
Query: 258 KSEADKKLYKTIRLXNGLTALLISDPS 338
KS DK+ Y+ + L NG+ LLISDP+
Sbjct: 42 KSPEDKREYRGLELANGIKVLLISDPT 68
>AF061243-1|AAC67244.1| 1038|Homo sapiens metalloprotease 1 protein.
Length = 1038
Score = 31.5 bits (68), Expect = 2.7
Identities = 12/28 (42%), Positives = 16/28 (57%)
Frame = +3
Query: 543 PAEIQGLAHFVXHMVFMGSEKYPKENEF 626
P + G+ H + H V GS+KYP N F
Sbjct: 96 PMDSTGVPHILEHTVLCGSQKYPCRNPF 123
>U80669-1|AAB38747.1| 234|Homo sapiens androgen regulated homeobox
protein protein.
Length = 234
Score = 29.9 bits (64), Expect = 8.3
Identities = 23/88 (26%), Positives = 32/88 (36%)
Frame = +3
Query: 243 LPEPIKSEADKKLYKTIRLXNGLTALLISDPSRPAVTXXXXXXXXXXXXXXDXNSDPESD 422
+PEP EA + LT+ LI D R + +PE +
Sbjct: 4 VPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPE 63
Query: 423 GGKSVQSATSDHHGTTXRNDFDEXKLXA 506
GG+S A +D T R DE + A
Sbjct: 64 GGRSRAGAQNDQLSTGPRAAPDEAETLA 91
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,244,481
Number of Sequences: 237096
Number of extensions: 1503750
Number of successful extensions: 2659
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 2588
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2659
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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