Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P02_F_I09
(651 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q5DU01 Cluster: MKIAA1073 protein; n=3; Murinae|Rep: MK... 130 4e-29
UniRef50_A2AHU7 Cluster: X-linked myotubular myopathy gene 1; n=... 126 5e-28
UniRef50_Q13613 Cluster: Myotubularin-related protein 1; n=110; ... 117 2e-25
UniRef50_UPI0000DBF6E0 Cluster: X-linked myotubular myopathy gen... 91 3e-17
UniRef50_Q4T107 Cluster: Chromosome undetermined SCAF10768, whol... 89 9e-17
UniRef50_Q9N589 Cluster: Mtm (Myotubularin) family protein 1; n=... 83 7e-15
UniRef50_Q1ZXD2 Cluster: GRAM domain-containing protein; n=1; Di... 47 3e-04
UniRef50_Q7QQF9 Cluster: GLP_91_5148_2896; n=1; Giardia lamblia ... 44 0.002
UniRef50_Q54TD5 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q5BYZ0 Cluster: SJCHGC06139 protein; n=2; Schistosoma j... 42 0.013
UniRef50_Q2UUC0 Cluster: Myotubularin-related phosphatidylinosit... 38 0.16
UniRef50_A6QS57 Cluster: Putative uncharacterized protein; n=1; ... 37 0.48
UniRef50_Q96EF0 Cluster: Myotubularin-related protein 8; n=7; Ca... 33 4.5
>UniRef50_Q5DU01 Cluster: MKIAA1073 protein; n=3; Murinae|Rep:
MKIAA1073 protein - Mus musculus (Mouse)
Length = 424
Score = 130 bits (313), Expect = 4e-29
Identities = 55/98 (56%), Positives = 71/98 (72%)
Frame = +2
Query: 356 LSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRGIFEKLQQLAF 535
L LGV+SR+EK+GGASS+GENSYG+ CKD+ NL FAH+ +RR IFE L + AF
Sbjct: 15 LDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAF 74
Query: 536 PLSHRLPMFAFSYSESFPEXGWHVYEPIAELXRMGVXN 649
P+S+ LP+FAF Y E FPE GW +Y+P+ E R G+ N
Sbjct: 75 PVSNGLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPN 112
>UniRef50_A2AHU7 Cluster: X-linked myotubular myopathy gene 1; n=5;
Euarchontoglires|Rep: X-linked myotubular myopathy gene
1 - Mus musculus (Mouse)
Length = 572
Score = 126 bits (304), Expect = 5e-28
Identities = 58/98 (59%), Positives = 71/98 (72%)
Frame = +2
Query: 356 LSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRGIFEKLQQLAF 535
L VPLGV+SRIEK+GGA+S+GENSYG+ I CKD+ NL FA +Q HSRR +FE L + AF
Sbjct: 83 LDVPLGVISRIEKMGGATSRGENSYGLDITCKDLRNLRFALKQEGHSRRDMFEILVKHAF 142
Query: 536 PLSHRLPMFAFSYSESFPEXGWHVYEPIAELXRMGVXN 649
PL+H LP+FAF E F GW VY P+ E R G+ N
Sbjct: 143 PLAHNLPLFAFVNEEKFNVDGWTVYNPVEEYRRQGLPN 180
Score = 37.1 bits (82), Expect = 0.36
Identities = 16/45 (35%), Positives = 29/45 (64%)
Frame = +1
Query: 184 SPHVLGDIQLLDGEKVTSVARDVTYLCPYSGPTRGVLKVTNYQLH 318
S V + L GE + + ++V Y+CP++GP +G + +TNY+L+
Sbjct: 28 SQDVSETVPRLPGELLIT-EKEVIYICPFNGPIKGRVYITNYRLY 71
>UniRef50_Q13613 Cluster: Myotubularin-related protein 1; n=110;
Eumetazoa|Rep: Myotubularin-related protein 1 - Homo
sapiens (Human)
Length = 665
Score = 117 bits (282), Expect = 2e-25
Identities = 55/98 (56%), Positives = 69/98 (70%)
Frame = +2
Query: 356 LSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRGIFEKLQQLAF 535
L VPLGV+SR+EK+G A S G+NS GI I CKDM NL A++Q S+ GIFE L + AF
Sbjct: 147 LDVPLGVISRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAF 205
Query: 536 PLSHRLPMFAFSYSESFPEXGWHVYEPIAELXRMGVXN 649
PLS+ +FAFSY E FP GW VY+P++E R G+ N
Sbjct: 206 PLSNGQALFAFSYKEKFPINGWKVYDPVSEYKRQGLPN 243
Score = 43.2 bits (97), Expect = 0.006
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 211 LLDGEKVTSVARDVTYLCPYSGPTRGVLKVTNYQLHF 321
L GE + ++ +DV Y+CP+ G G L VT+++L+F
Sbjct: 100 LFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYF 136
>UniRef50_UPI0000DBF6E0 Cluster: X-linked myotubular myopathy gene
1; n=1; Rattus norvegicus|Rep: X-linked myotubular
myopathy gene 1 - Rattus norvegicus
Length = 162
Score = 90.6 bits (215), Expect = 3e-17
Identities = 41/66 (62%), Positives = 52/66 (78%)
Frame = +2
Query: 356 LSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRGIFEKLQQLAF 535
L VPLGV+SRIEK+GG +S+GENSYG+ I CKD+ NL FA +Q HSRR IF+ L + AF
Sbjct: 82 LDVPLGVISRIEKMGGVTSRGENSYGLDITCKDLRNLRFALKQEGHSRRDIFDVLTRHAF 141
Query: 536 PLSHRL 553
PL++ L
Sbjct: 142 PLAYNL 147
Score = 41.1 bits (92), Expect = 0.022
Identities = 16/33 (48%), Positives = 25/33 (75%)
Frame = +1
Query: 220 GEKVTSVARDVTYLCPYSGPTRGVLKVTNYQLH 318
GE +T ++V Y+CP+SGP +G L +TNY+L+
Sbjct: 40 GEXITD--KEVIYICPFSGPVKGRLYITNYRLY 70
>UniRef50_Q4T107 Cluster: Chromosome undetermined SCAF10768, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10768,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 759
Score = 89.0 bits (211), Expect = 9e-17
Identities = 42/102 (41%), Positives = 64/102 (62%)
Frame = +2
Query: 344 TLGTLSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRGIFEKLQ 523
+L V LG +SR+E + + GE + G+ + CKDM + FA+++ ++ + + E L
Sbjct: 121 SLFIFDVNLGAISRLETIS-VPNLGEKTEGLELVCKDMRSPRFAYKKESN-QPDVVEVLS 178
Query: 524 QLAFPLSHRLPMFAFSYSESFPEXGWHVYEPIAELXRMGVXN 649
+ AFPLSH LP+FAF Y E FP GW VY+P++E R G+ N
Sbjct: 179 KHAFPLSHNLPLFAFLYKEQFPVDGWKVYDPVSEYKRQGLPN 220
Score = 49.6 bits (113), Expect = 6e-05
Identities = 19/41 (46%), Positives = 29/41 (70%)
Frame = +1
Query: 205 IQLLDGEKVTSVARDVTYLCPYSGPTRGVLKVTNYQLHFST 327
+ LL GE V + +DV Y+CP+SG G L +T+Y+LHF++
Sbjct: 49 VPLLPGETVQTTLKDVMYICPFSGLLNGTLTITDYKLHFAS 89
>UniRef50_Q9N589 Cluster: Mtm (Myotubularin) family protein 1; n=2;
Caenorhabditis|Rep: Mtm (Myotubularin) family protein 1
- Caenorhabditis elegans
Length = 588
Score = 82.6 bits (195), Expect = 7e-15
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 7/105 (6%)
Frame = +2
Query: 356 LSVPLGVVSRIEKVG----GASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRGIFEKLQ 523
L +PLG VSRIEKVG + +G+++YG I+CKD F + R+ + + L
Sbjct: 77 LDIPLGQVSRIEKVGRKTTSVAKRGDDNYGFTIYCKDYRVYRFTCNPASSDRKNVCDSLN 136
Query: 524 QLAFPLSHRLPMFAFSYSESFP---EXGWHVYEPIAELXRMGVXN 649
+ AFPLSH LPMFA ++ P + GW +Y E R+G+ N
Sbjct: 137 RYAFPLSHNLPMFASVHAAETPRLMKDGWKIYSAEKEYERLGIPN 181
>UniRef50_Q1ZXD2 Cluster: GRAM domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: GRAM domain-containing
protein - Dictyostelium discoideum AX4
Length = 1227
Score = 47.2 bits (107), Expect = 3e-04
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Frame = +2
Query: 338 SATLGT--LSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRG-- 505
SAT+G +S+PL +S+I K G + Y + CKD F H + ++
Sbjct: 717 SATVGDKIISIPLTTISKIFKCVGFTLDKVKYYAFELTCKDFNRARFMHLPGSSQQKANS 776
Query: 506 -IFEKLQQLAFPLSHRL-PMFAFSYSESF-PEXGWHVYEPIAELXRMGVXN 649
+FE L+ L F + +F F E GW++Y+ + E R + N
Sbjct: 777 RLFEILESLIFKQKQQYHQLFCFKNEEILGGYDGWNIYQALKEFARQSIPN 827
>UniRef50_Q7QQF9 Cluster: GLP_91_5148_2896; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_91_5148_2896 - Giardia lamblia ATCC
50803
Length = 750
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Frame = +2
Query: 359 SVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSR-RGIF-EKLQQLA 532
S+P +V I K+GG S+ ++YG+ I + L FA H++ R IF L + A
Sbjct: 82 SIPHFMVVSISKIGGKKSR--DAYGVLISL--ITPLQFAVFLPRHNKQRTIFIGTLLKYA 137
Query: 533 FP---LSHRLPMFAFSYSESFPEXGWHVYEPIAELXRMGV 643
P L+H P F+ ++ E GW +Y+P AE R GV
Sbjct: 138 SPRLTLTHLFPCFSL-FTSPKAEKGWFIYDPFAEYCRQGV 176
>UniRef50_Q54TD5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1343
Score = 44.0 bits (99), Expect = 0.003
Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 NFTLAPTDPSATLGTLSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXN 490
N+ P S L +PLG V + EK K I I CKD+ F N
Sbjct: 58 NYNNTPIFSSRESELLEIPLGSVLKFEKFQTKKDKV-----IDIICKDIRQYRFFFTLDN 112
Query: 491 HSRRGIFEKLQQLAFPLSHRLPMFAFSYSE--SFPEXGWHVYEPIAELXRMGVXN 649
+ I K + +P+S +AFS +E S+ GW++Y+ E RMG+ N
Sbjct: 113 VNVEEIELKFNKY-YPISIE-KSYAFSNNEKFSYDTKGWYIYDAEKEYNRMGISN 165
>UniRef50_Q5BYZ0 Cluster: SJCHGC06139 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC06139 protein - Schistosoma
japonicum (Blood fluke)
Length = 210
Score = 41.9 bits (94), Expect = 0.013
Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 6/102 (5%)
Frame = +2
Query: 356 LSVPLGVVSRIEKVGGASSKGENSYGIXIFCKDMXNLXFAHRQXNHSRRGIFEKLQQLAF 535
L PLG + I++ + S + I CKD+ L F + E L+ AF
Sbjct: 76 LKFPLGTIRNIDQ-----KSNQGSISLHINCKDIRELVFTFADCGRTNE-FLENLKAYAF 129
Query: 536 PLSHRLPMFAFSYSES------FPEXGWHVYEPIAELXRMGV 643
P + +FA+ Y F GW VY P E R +
Sbjct: 130 PALSKKTLFAYLYGAKCIANNIFATDGWDVYNPEEEYHRQNI 171
>UniRef50_Q2UUC0 Cluster: Myotubularin-related phosphatidylinositol
3-phosphate 3-phosphatase MTM6; n=5; Pezizomycotina|Rep:
Myotubularin-related phosphatidylinositol 3-phosphate
3-phosphatase MTM6 - Aspergillus oryzae
Length = 763
Score = 38.3 bits (85), Expect = 0.16
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Frame = +2
Query: 434 IXIFCKDMXNLXFAHRQXNHSRRGIFEKLQQLAFPLSHRLPMFAFSYSESFPEX---GWH 604
I + C+D + F R ++E ++Q L ++AF+Y PE GW
Sbjct: 81 IRLRCRDFAFVCFYFASETKGR-DVYESIKQWTCKLGRIEKLYAFTYQPPPPERELNGWE 139
Query: 605 VYEPIAELXRMGV 643
+Y+P+ E R GV
Sbjct: 140 LYDPLKEWARQGV 152
>UniRef50_A6QS57 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 884
Score = 36.7 bits (81), Expect = 0.48
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +2
Query: 404 ASSKGENSYGIXIFCKDMXNLXFAHRQXNHSR-RGIFEKLQQLAFPLSHRLPMFAFSYSE 580
ASS+ +S I + C+D + F+ N SR R +E ++ L ++AF+Y
Sbjct: 195 ASSRQPSS--IRLRCRDFTFVCFSFP--NESRARDAYESIKSWTCRLGRIEKLYAFTYQP 250
Query: 581 SFPEXG---WHVYEPIAELXRMGV 643
PE G W++Y P E R+GV
Sbjct: 251 PPPERGFNGWNIYNPREEWLRLGV 274
>UniRef50_Q96EF0 Cluster: Myotubularin-related protein 8; n=7;
Catarrhini|Rep: Myotubularin-related protein 8 - Homo
sapiens (Human)
Length = 704
Score = 33.5 bits (73), Expect = 4.5
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 4/49 (8%)
Frame = +2
Query: 515 KLQQLAFPLSHRLPMFAFSY----SESFPEXGWHVYEPIAELXRMGVXN 649
KL Q A P ++AFSY S+ E GW + +PI++ RMG+ N
Sbjct: 99 KLSQPALPED----LYAFSYNPKSSKEMRESGWKLIDPISDFGRMGIPN 143
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 576,158,440
Number of Sequences: 1657284
Number of extensions: 10332712
Number of successful extensions: 23419
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 22736
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 23406
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -