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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fe100P02_F_C05
         (654 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D49387-1|BAA08382.1|  311|Homo sapiens NADP dependent leukotrien...   102   1e-21
BC035228-1|AAH35228.1|  329|Homo sapiens leukotriene B4 12-hydro...   102   1e-21
AL135787-3|CAC22151.1|  329|Homo sapiens leukotriene B4 12-hydro...   102   1e-21
AL135787-2|CAI12401.1|  177|Homo sapiens leukotriene B4 12-hydro...    69   2e-11
AL135787-4|CAI12402.1|  119|Homo sapiens leukotriene B4 12-hydro...    53   1e-06
BC059364-1|AAH59364.1|  351|Homo sapiens zinc binding alcohol de...    44   6e-04
AY424308-1|AAR82927.1|  351|Homo sapiens zinc binding alcohol de...    44   6e-04
AY346133-1|AAR05101.1|  351|Homo sapiens zinc binding alcohol de...    44   6e-04
AK096410-1|BAC04781.1|  351|Homo sapiens protein ( Homo sapiens ...    44   6e-04
AL135787-5|CAC22152.1|   70|Homo sapiens leukotriene B4 12-hydro...    37   0.055

>D49387-1|BAA08382.1|  311|Homo sapiens NADP dependent leukotriene
           b4 12-hydroxydehydrogenase protein.
          Length = 311

 Score =  102 bits (244), Expect = 1e-21
 Identities = 61/160 (38%), Positives = 85/160 (53%)
 Frame = +3

Query: 174 LKAEWISVDPYLRAYNSYQAVPYDQFSYQVGVVVQSRDSNYPVGTRVVAHKGWCDHYVFT 353
           L+A +++VDPY+R               QV  VV+S++   P GT V+A  GW  H +  
Sbjct: 39  LEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSI-- 96

Query: 354 PSTQPNTPKDRIYKLPDLQGLSPSLGVGAVGMPGATAYFGFLEICKPKXXXXXXXXXXXX 533
             +     +  + + PD   LS  L +G VGMPG TAYFG LEIC  K            
Sbjct: 97  --SDGKDLEKLLTEWPDTIPLS--LALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAG 152

Query: 534 XXXSLVGQIAXIKGCRVIXFAGTDDKVKWLEEELGFDKAF 653
              S+VGQIA +KGC+V+   G+D+KV +L ++LGFD  F
Sbjct: 153 AVGSVVGQIAKLKGCKVVGAVGSDEKVAYL-QKLGFDVVF 191



 Score = 37.1 bits (82), Expect = 0.055
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 59  MTSAXKYVVKNHFKGVPKQEDYELXEFVIPPLIDGEVL 172
           M     + +K HF G P   D+EL    +PPL +GEVL
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38


>BC035228-1|AAH35228.1|  329|Homo sapiens leukotriene B4
           12-hydroxydehydrogenase protein.
          Length = 329

 Score =  102 bits (244), Expect = 1e-21
 Identities = 61/160 (38%), Positives = 85/160 (53%)
 Frame = +3

Query: 174 LKAEWISVDPYLRAYNSYQAVPYDQFSYQVGVVVQSRDSNYPVGTRVVAHKGWCDHYVFT 353
           L+A +++VDPY+R               QV  VV+S++   P GT V+A  GW  H +  
Sbjct: 39  LEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSI-- 96

Query: 354 PSTQPNTPKDRIYKLPDLQGLSPSLGVGAVGMPGATAYFGFLEICKPKXXXXXXXXXXXX 533
             +     +  + + PD   LS  L +G VGMPG TAYFG LEIC  K            
Sbjct: 97  --SDGKDLEKLLTEWPDTIPLS--LALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAG 152

Query: 534 XXXSLVGQIAXIKGCRVIXFAGTDDKVKWLEEELGFDKAF 653
              S+VGQIA +KGC+V+   G+D+KV +L ++LGFD  F
Sbjct: 153 AVGSVVGQIAKLKGCKVVGAVGSDEKVAYL-QKLGFDVVF 191



 Score = 37.1 bits (82), Expect = 0.055
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 59  MTSAXKYVVKNHFKGVPKQEDYELXEFVIPPLIDGEVL 172
           M     + +K HF G P   D+EL    +PPL +GEVL
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTSELPPLKNGEVL 38


>AL135787-3|CAC22151.1|  329|Homo sapiens leukotriene B4
           12-hydroxydehydrogenase protein.
          Length = 329

 Score =  102 bits (244), Expect = 1e-21
 Identities = 61/160 (38%), Positives = 85/160 (53%)
 Frame = +3

Query: 174 LKAEWISVDPYLRAYNSYQAVPYDQFSYQVGVVVQSRDSNYPVGTRVVAHKGWCDHYVFT 353
           L+A +++VDPY+R               QV  VV+S++   P GT V+A  GW  H +  
Sbjct: 39  LEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSI-- 96

Query: 354 PSTQPNTPKDRIYKLPDLQGLSPSLGVGAVGMPGATAYFGFLEICKPKXXXXXXXXXXXX 533
             +     +  + + PD   LS  L +G VGMPG TAYFG LEIC  K            
Sbjct: 97  --SDGKDLEKLLTEWPDTIPLS--LALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAG 152

Query: 534 XXXSLVGQIAXIKGCRVIXFAGTDDKVKWLEEELGFDKAF 653
              S+VGQIA +KGC+V+   G+D+KV +L ++LGFD  F
Sbjct: 153 AVGSVVGQIAKLKGCKVVGAVGSDEKVAYL-QKLGFDVVF 191



 Score = 37.1 bits (82), Expect = 0.055
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 59  MTSAXKYVVKNHFKGVPKQEDYELXEFVIPPLIDGEVL 172
           M     + +K HF G P   D+EL    +PPL +GEVL
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38


>AL135787-2|CAI12401.1|  177|Homo sapiens leukotriene B4
           12-hydroxydehydrogenase protein.
          Length = 177

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 33/69 (47%), Positives = 42/69 (60%)
 Frame = +3

Query: 447 MPGATAYFGFLEICKPKXXXXXXXXXXXXXXXSLVGQIAXIKGCRVIXFAGTDDKVKWLE 626
           MPG TAYFG LEIC  K               S+VGQIA +KGC+V+   G+D+KV +L 
Sbjct: 1   MPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL- 59

Query: 627 EELGFDKAF 653
           ++LGFD  F
Sbjct: 60  QKLGFDVVF 68


>AL135787-4|CAI12402.1|  119|Homo sapiens leukotriene B4
           12-hydroxydehydrogenase protein.
          Length = 119

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 31/73 (42%), Positives = 41/73 (56%)
 Frame = +3

Query: 270 VVQSRDSNYPVGTRVVAHKGWCDHYVFTPSTQPNTPKDRIYKLPDLQGLSPSLGVGAVGM 449
           VV+S++   P GT V+A  GW  H +    +     +  + + PD   LS  L +G VGM
Sbjct: 52  VVESKNVALPKGTIVLASPGWTTHSI----SDGKDLEKLLTEWPDTIPLS--LALGTVGM 105

Query: 450 PGATAYFGFLEIC 488
           PG TAYFG LEIC
Sbjct: 106 PGLTAYFGLLEIC 118



 Score = 37.1 bits (82), Expect = 0.055
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 59  MTSAXKYVVKNHFKGVPKQEDYELXEFVIPPLIDGEVL 172
           M     + +K HF G P   D+EL    +PPL +GEVL
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38


>BC059364-1|AAH59364.1|  351|Homo sapiens zinc binding alcohol
           dehydrogenase, domain containing 1 protein.
          Length = 351

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 48/168 (28%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
 Frame = +3

Query: 186 WISVDPYLRA-YNSYQAVPYD---QFSYQV-----GVVVQSRDSNYPVGTRVVAHKGWCD 338
           ++SVDPY+R   N      Y    Q S  V     G++ +S+ +N   G  V +      
Sbjct: 45  YLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTS------ 98

Query: 339 HYVFTPSTQPNTPKDRIYKL-PDLQGLSPSLGVGAVGMPGATAYFGFLEI--CKPKXXXX 509
            + +   T+     + + K+ P L     S  +GA+GMPG T+  G  E           
Sbjct: 99  -FYWPWQTKVILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKT 157

Query: 510 XXXXXXXXXXXSLVGQIAXIKGC-RVIXFAGTDDKVKWLEEELGFDKA 650
                      S+ GQI    GC RV+   GT +K   L  ELGFD A
Sbjct: 158 MVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205


>AY424308-1|AAR82927.1|  351|Homo sapiens zinc binding alcohol
           dehydrogenase protein.
          Length = 351

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 48/168 (28%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
 Frame = +3

Query: 186 WISVDPYLRA-YNSYQAVPYD---QFSYQV-----GVVVQSRDSNYPVGTRVVAHKGWCD 338
           ++SVDPY+R   N      Y    Q S  V     G++ +S+ +N   G  V +      
Sbjct: 45  YLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTS------ 98

Query: 339 HYVFTPSTQPNTPKDRIYKL-PDLQGLSPSLGVGAVGMPGATAYFGFLEI--CKPKXXXX 509
            + +   T+     + + K+ P L     S  +GA+GMPG T+  G  E           
Sbjct: 99  -FYWPWQTKVILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKT 157

Query: 510 XXXXXXXXXXXSLVGQIAXIKGC-RVIXFAGTDDKVKWLEEELGFDKA 650
                      S+ GQI    GC RV+   GT +K   L  ELGFD A
Sbjct: 158 MVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205


>AY346133-1|AAR05101.1|  351|Homo sapiens zinc binding alcohol
           dehydrogenase domain containing 1 protein protein.
          Length = 351

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 48/168 (28%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
 Frame = +3

Query: 186 WISVDPYLRA-YNSYQAVPYD---QFSYQV-----GVVVQSRDSNYPVGTRVVAHKGWCD 338
           ++SVDPY+R   N      Y    Q S  V     G++ +S+ +N   G  V +      
Sbjct: 45  YLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTS------ 98

Query: 339 HYVFTPSTQPNTPKDRIYKL-PDLQGLSPSLGVGAVGMPGATAYFGFLEI--CKPKXXXX 509
            + +   T+     + + K+ P L     S  +GA+GMPG T+  G  E           
Sbjct: 99  -FYWPWQTKVILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKT 157

Query: 510 XXXXXXXXXXXSLVGQIAXIKGC-RVIXFAGTDDKVKWLEEELGFDKA 650
                      S+ GQI    GC RV+   GT +K   L  ELGFD A
Sbjct: 158 MVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205


>AK096410-1|BAC04781.1|  351|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39091 fis, clone NT2RP7019543, weakly similar to
           NADP-DEPENDENT OXIDOREDUCTASE IN TEHB-RHSE INTERGENIC
           REGION ).
          Length = 351

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 48/168 (28%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
 Frame = +3

Query: 186 WISVDPYLRA-YNSYQAVPYD---QFSYQV-----GVVVQSRDSNYPVGTRVVAHKGWCD 338
           ++SVDPY+R   N      Y    Q S  V     G++ +S+ +N   G  V +      
Sbjct: 45  YLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTS------ 98

Query: 339 HYVFTPSTQPNTPKDRIYKL-PDLQGLSPSLGVGAVGMPGATAYFGFLEI--CKPKXXXX 509
            + +   T+     + + K+ P L     S  +GA+GMPG T+  G  E           
Sbjct: 99  -FYWPWQTKVILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKT 157

Query: 510 XXXXXXXXXXXSLVGQIAXIKGC-RVIXFAGTDDKVKWLEEELGFDKA 650
                      S+ GQI    GC RV+   GT +K   L  ELGFD A
Sbjct: 158 MVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205


>AL135787-5|CAC22152.1|   70|Homo sapiens leukotriene B4
           12-hydroxydehydrogenase protein.
          Length = 70

 Score = 37.1 bits (82), Expect = 0.055
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 59  MTSAXKYVVKNHFKGVPKQEDYELXEFVIPPLIDGEVL 172
           M     + +K HF G P   D+EL    +PPL +GEVL
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,629,595
Number of Sequences: 237096
Number of extensions: 1873294
Number of successful extensions: 4257
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3962
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4250
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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