Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P02_F_B18
(653 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein. 314 2e-85
AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2 prot... 314 2e-85
AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens ... 309 5e-84
AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1 prot... 307 2e-83
AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein. 307 2e-83
AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens ... 75 2e-13
U57627-1|AAB03839.2| 901|Homo sapiens ocrl1 protein. 31 3.6
M88162-1|AAA59964.2| 968|Homo sapiens Lowe oculocerebrorenal sy... 31 3.6
BC130612-1|AAI30613.1| 893|Homo sapiens oculocerebrorenal syndr... 31 3.6
BC094726-1|AAH94726.1| 893|Homo sapiens oculocerebrorenal syndr... 31 3.6
AL662877-2|CAI41087.1| 893|Homo sapiens oculocerebrorenal syndr... 31 3.6
AL662877-1|CAI41088.1| 901|Homo sapiens oculocerebrorenal syndr... 31 3.6
AL138745-5|CAI42615.1| 893|Homo sapiens oculocerebrorenal syndr... 31 3.6
AL138745-4|CAI42616.1| 901|Homo sapiens oculocerebrorenal syndr... 31 3.6
AL022162-2|CAI95696.1| 893|Homo sapiens oculocerebrorenal syndr... 31 3.6
AL022162-1|CAI95695.1| 901|Homo sapiens oculocerebrorenal syndr... 31 3.6
>BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein.
Length = 418
Score = 314 bits (770), Expect = 2e-85
Identities = 147/159 (92%), Positives = 156/159 (98%)
Frame = +3
Query: 177 MGIKFLEVIKPFCSILPEIAKPERKIQFRXKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 356
MGIKFLEVIKPFC++LPEI KPERKIQFR KVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 357 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAXKLFG 536
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGA KLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 537 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAG 653
M+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFVAG
Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAG 159
>AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2
protein.
Length = 476
Score = 314 bits (770), Expect = 2e-85
Identities = 147/159 (92%), Positives = 156/159 (98%)
Frame = +3
Query: 177 MGIKFLEVIKPFCSILPEIAKPERKIQFRXKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 356
MGIKFLEVIKPFC++LPEI KPERKIQFR KVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 357 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAXKLFG 536
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGA KLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 537 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAG 653
M+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFVAG
Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAG 159
>AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens
cDNA FLJ12578 fis, clone NT2RM4001054, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 437
Score = 309 bits (759), Expect = 5e-84
Identities = 145/159 (91%), Positives = 155/159 (97%)
Frame = +3
Query: 177 MGIKFLEVIKPFCSILPEIAKPERKIQFRXKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 356
MGIKFLEVIKPFC++ PEI KPERKIQFR KVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVPPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 357 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAXKLFG 536
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGA KLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 537 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAG 653
M+IT+GQAIVYV+TGMYG+P+E+GAG+CLLIIIQLFVAG
Sbjct: 121 MIITIGQAIVYVITGMYGDPAEMGAGICLLIIIQLFVAG 159
>AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1
protein.
Length = 476
Score = 307 bits (754), Expect = 2e-83
Identities = 145/159 (91%), Positives = 153/159 (96%)
Frame = +3
Query: 177 MGIKFLEVIKPFCSILPEIAKPERKIQFRXKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 356
M IKFLEVIKPFC ILPEI KPERKIQF+ KVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 357 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAXKLFG 536
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGA KLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 537 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAG 653
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAG
Sbjct: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAG 159
>AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein.
Length = 476
Score = 307 bits (754), Expect = 2e-83
Identities = 145/159 (91%), Positives = 153/159 (96%)
Frame = +3
Query: 177 MGIKFLEVIKPFCSILPEIAKPERKIQFRXKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 356
M IKFLEVIKPFC ILPEI KPERKIQF+ KVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 357 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAXKLFG 536
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGA KLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 537 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAG 653
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAG
Sbjct: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAG 159
>AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ90447 fis, clone NT2RP3001240, highly similar to
Canis familiaris sec61 homologue mRNA. ).
Length = 356
Score = 74.9 bits (176), Expect = 2e-13
Identities = 32/39 (82%), Positives = 38/39 (97%)
Frame = +3
Query: 537 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAG 653
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAG
Sbjct: 1 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAG 39
>U57627-1|AAB03839.2| 901|Homo sapiens ocrl1 protein.
Length = 901
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 765 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 824
Query: 386 IKQ 394
I Q
Sbjct: 825 ISQ 827
>M88162-1|AAA59964.2| 968|Homo sapiens Lowe oculocerebrorenal
syndrome protein protein.
Length = 968
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 832 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 891
Query: 386 IKQ 394
I Q
Sbjct: 892 ISQ 894
>BC130612-1|AAI30613.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 757 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 816
Query: 386 IKQ 394
I Q
Sbjct: 817 ISQ 819
>BC094726-1|AAH94726.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 757 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 816
Query: 386 IKQ 394
I Q
Sbjct: 817 ISQ 819
>AL662877-2|CAI41087.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 757 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 816
Query: 386 IKQ 394
I Q
Sbjct: 817 ISQ 819
>AL662877-1|CAI41088.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 765 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 824
Query: 386 IKQ 394
I Q
Sbjct: 825 ISQ 827
>AL138745-5|CAI42615.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 757 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 816
Query: 386 IKQ 394
I Q
Sbjct: 817 ISQ 819
>AL138745-4|CAI42616.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 765 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 824
Query: 386 IKQ 394
I Q
Sbjct: 825 ISQ 827
>AL022162-2|CAI95696.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 757 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 816
Query: 386 IKQ 394
I Q
Sbjct: 817 ISQ 819
>AL022162-1|CAI95695.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 31.1 bits (67), Expect = 3.6
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +2
Query: 212 LQYIARNSETRT*DSIPXESIMDSNHIIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSC 385
LQ I +T ++IP + + ++ FL LP+ +I Y + ++C DP C
Sbjct: 765 LQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQV 824
Query: 386 IKQ 394
I Q
Sbjct: 825 ISQ 827
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,543,374
Number of Sequences: 237096
Number of extensions: 1838789
Number of successful extensions: 3637
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3528
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3637
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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