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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fe100P01_F_K04
         (651 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00003C0C03 Cluster: PREDICTED: similar to FUN14 doma...   117   3e-25
UniRef50_Q4PM91 Cluster: FUN14 family protein; n=1; Ixodes scapu...    76   6e-13
UniRef50_Q8IVP5 Cluster: FUN14 domain-containing protein 1; n=33...    69   1e-10
UniRef50_Q9VL16 Cluster: CG5676-PA; n=7; Endopterygota|Rep: CG56...    68   2e-10
UniRef50_Q9BWH2 Cluster: FUN14 domain-containing protein 2; n=21...    63   6e-09
UniRef50_Q5HYP8 Cluster: FUN14 domain containing 2; n=4; Eutheri...    63   6e-09
UniRef50_A7SUB5 Cluster: Predicted protein; n=1; Nematostella ve...    59   8e-08
UniRef50_UPI0000DA41AA Cluster: PREDICTED: similar to FUN14 doma...    56   6e-07
UniRef50_Q4S9P0 Cluster: Chromosome 2 SCAF14695, whole genome sh...    55   1e-06
UniRef50_Q22252 Cluster: Putative uncharacterized protein; n=2; ...    46   8e-04
UniRef50_Q54Z98 Cluster: Putative uncharacterized protein; n=2; ...    37   0.36 
UniRef50_Q23UD5 Cluster: FUN14 family protein; n=1; Tetrahymena ...    33   4.5  
UniRef50_UPI00006CE593 Cluster: hypothetical protein TTHERM_0014...    33   5.9  

>UniRef50_UPI00003C0C03 Cluster: PREDICTED: similar to FUN14 domain
           containing 1; n=1; Apis mellifera|Rep: PREDICTED:
           similar to FUN14 domain containing 1 - Apis mellifera
          Length = 142

 Score =  117 bits (281), Expect = 3e-25
 Identities = 51/138 (36%), Positives = 82/138 (59%)
 Frame = +1

Query: 142 MAKPKNEDASEEAKKIVDDAKNFIERAIADIGKTSATKQLILGTASGWITGFISMXXXXX 321
           + K   ++A++E   I   A++ I++ + D+ K S TKQ+I+GT SGW+TGFI++     
Sbjct: 5   VTKKNKDNANKEELNISKHAESMIDKILGDVNKKSTTKQIIIGTTSGWLTGFITIKIGKI 64

Query: 322 XXXXXXXXXXXXXXXSQKGYIDINWDKINKKVDXISDKIEKEATGKSPDWFEKVFVFVKS 501
                          + +GYI INWDKI KK + I+DK+E+  TG+ P + +KV  + ++
Sbjct: 65  TAFAVGGGIIMLQIAAHQGYIKINWDKIQKKAEKITDKVEETVTGEGPKFLDKVGTWCRN 124

Query: 502 NSYYSAGFTGGFLFGIAS 555
           NS  +  F GGF+ G+AS
Sbjct: 125 NSLVATSFIGGFIIGLAS 142


>UniRef50_Q4PM91 Cluster: FUN14 family protein; n=1; Ixodes
           scapularis|Rep: FUN14 family protein - Ixodes scapularis
           (Black-legged tick) (Deer tick)
          Length = 141

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 34/110 (30%), Positives = 53/110 (48%)
 Frame = +1

Query: 229 DIGKTSATKQLILGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKIN 408
           D+ K S  KQL +G  SGW  GF+                        +GY+ +NW ++N
Sbjct: 32  DLTKASPAKQLTVGGVSGWCVGFVFTKAGKVAATAIGGSLLLFQIAQHQGYVKVNWTRLN 91

Query: 409 KKVDXISDKIEKEATGKSPDWFEKVFVFVKSNSYYSAGFTGGFLFGIASS 558
           K +    +++ + A  K P   E+   F++ N + + GF GGFL G+ASS
Sbjct: 92  KDMQQAKNELARRANSKLPRIVEEGQQFIQDNIFLATGFLGGFLLGMASS 141


>UniRef50_Q8IVP5 Cluster: FUN14 domain-containing protein 1; n=33;
           Euteleostomi|Rep: FUN14 domain-containing protein 1 -
           Homo sapiens (Human)
          Length = 155

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 3/111 (2%)
 Frame = +1

Query: 232 IGKTSATKQLILGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKINK 411
           + K S   Q+++G  +GW  GF+                      S  GY+ I+W ++ K
Sbjct: 45  VEKYSVATQIVMGGVTGWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEK 104

Query: 412 KVDXISDKIEKEATGKSPD---WFEKVFVFVKSNSYYSAGFTGGFLFGIAS 555
            V+    +I+K A   +P+     E+   F+K N   S+GF GGFL G+AS
Sbjct: 105 DVNKAKRQIKKRANKAAPEINNLIEEATEFIKQNIVISSGFVGGFLLGLAS 155


>UniRef50_Q9VL16 Cluster: CG5676-PA; n=7; Endopterygota|Rep:
           CG5676-PA - Drosophila melanogaster (Fruit fly)
          Length = 156

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 30/94 (31%), Positives = 51/94 (54%)
 Frame = +1

Query: 214 ERAIADIGKTSATKQLILGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDIN 393
           ++   DIG+ SA  Q+++G +SGW+TG+ +M                     Q+G I IN
Sbjct: 9   KKVFNDIGQRSAYSQMLIGVSSGWVTGYTTMKIGKFAAFAVGGSIILLEIAHQEGLIKIN 68

Query: 394 WDKINKKVDXISDKIEKEATGKSPDWFEKVFVFV 495
           W K++K VD ++DK+E  + G+  +W +K   +V
Sbjct: 69  WSKLDKSVDKLADKVE-ASLGREKNWKDKTERYV 101


>UniRef50_Q9BWH2 Cluster: FUN14 domain-containing protein 2; n=21;
           Theria|Rep: FUN14 domain-containing protein 2 - Homo
           sapiens (Human)
          Length = 189

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
 Frame = +1

Query: 163 DASEEAKKIVDDAKNFIERAIADIGKTSATKQLILGTASGWITGFISMXXXXXXXXXXXX 342
           D +E AKK     K F + +     K S   QL +G  +GW TGFI              
Sbjct: 55  DLAEFAKKQPWWRKLFGQESGPSAEKYSVATQLFIGGVTGWCTGFIFQKVGKLAATAVGG 114

Query: 343 XXXXXXXXSQKGYIDINWDKINKKVDXISDKIEKEATGKSPDWF----EKVFVFVKSNSY 510
                   +  GYI ++W ++ K +    ++++   + + P       E+V  FVK N  
Sbjct: 115 GFFLLQLANHTGYIKVDWQRVEKDMKKAKEQLKIRKSNQIPTEVRSKAEEVVSFVKKNVL 174

Query: 511 YSAGFTGGFLFGIAS 555
            + GF GGFL G+AS
Sbjct: 175 VTGGFFGGFLLGMAS 189


>UniRef50_Q5HYP8 Cluster: FUN14 domain containing 2; n=4;
           Eutheria|Rep: FUN14 domain containing 2 - Homo sapiens
           (Human)
          Length = 218

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 4/135 (2%)
 Frame = +1

Query: 163 DASEEAKKIVDDAKNFIERAIADIGKTSATKQLILGTASGWITGFISMXXXXXXXXXXXX 342
           D +E AKK     K F + +     K S   QL +G  +GW TGFI              
Sbjct: 84  DLAEFAKKQPWWRKLFGQESGPSAEKYSVATQLFIGGVTGWCTGFIFQKVGKLAATAVGG 143

Query: 343 XXXXXXXXSQKGYIDINWDKINKKVDXISDKIEKEATGKSPDWF----EKVFVFVKSNSY 510
                   +  GYI ++W ++ K +    ++++   + + P       E+V  FVK N  
Sbjct: 144 GFFLLQLANHTGYIKVDWQRVEKDMKKAKEQLKIRKSNQIPTEVRSKAEEVVSFVKKNVL 203

Query: 511 YSAGFTGGFLFGIAS 555
            + GF GGFL G+AS
Sbjct: 204 VTGGFFGGFLLGMAS 218


>UniRef50_A7SUB5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 155

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 17/154 (11%)
 Frame = +1

Query: 142 MAKPKN--EDASEEAKKIVDDA----KNFIERAIA-DIGKTSATKQLILGTASGWITGFI 300
           M+ P++  ED+ EE  +I++      ++ +   ++ D+G  +  +Q+ +G A+GW  G++
Sbjct: 1   MSDPESDKEDSQEEPYEIIETPGARQQDLLRDLMSMDLGNRTTIQQIGIGGATGWFAGYM 60

Query: 301 SMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKINKKVDXISDKIEKE----ATGKSP- 465
                                  + GYI+INW K+ K  + +S  +E+E    A G S  
Sbjct: 61  CKKIGKLTISAIGGGILILQIAHKTGYININWKKVEKDYNKVSRHVEREVYKVAQGNSST 120

Query: 466 -----DWFEKVFVFVKSNSYYSAGFTGGFLFGIA 552
                    ++F + K N   ++GF GGFL G+A
Sbjct: 121 EQRIVGTGRQIFDYAKRNMAAASGFAGGFLIGMA 154


>UniRef50_UPI0000DA41AA Cluster: PREDICTED: similar to FUN14 domain
           containing 2 isoform 1; n=4; Rattus norvegicus|Rep:
           PREDICTED: similar to FUN14 domain containing 2 isoform
           1 - Rattus norvegicus
          Length = 183

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 4/110 (3%)
 Frame = +1

Query: 238 KTSATKQLILGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKINKKV 417
           K SA  QL +G  +GW TG +                      S  GYI ++W ++ K V
Sbjct: 74  KYSAATQLAVGGVTGWCTGLVFRKVGKLAATALGGGFFLLQLASHTGYIRVDWQRLEKDV 133

Query: 418 DXISDKIEKEATGKSPDWF----EKVFVFVKSNSYYSAGFTGGFLFGIAS 555
                +++     + P       E+   FVK N   +AGF GGFL G+AS
Sbjct: 134 KKAKAQLKIHRGRQMPTEVGSKAEEALSFVKKNVPVAAGFLGGFLLGLAS 183


>UniRef50_Q4S9P0 Cluster: Chromosome 2 SCAF14695, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 2 SCAF14695, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 164

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = +1

Query: 238 KTSATKQLILGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKINKKV 417
           K     QL +G+ SGW  G+I                         GYI ++W ++ K +
Sbjct: 58  KYPTATQLAIGSLSGWCVGYIFQKVGKVAAMSVGGGLLLLPVAYNTGYIKVDWKRVEKDI 117

Query: 418 DXISDKIEKEATGKSPDWF-EKVFVFVKSNSYYSAGFTGGFLFGIAS 555
           +   +++ + +     + F +K  VFVK N   ++GF GGFL  + S
Sbjct: 118 NKAKEQLNQSSEAAELNTFVKKSKVFVKQNIVLTSGFIGGFLLAMVS 164


>UniRef50_Q22252 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 138

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/133 (24%), Positives = 50/133 (37%)
 Frame = +1

Query: 154 KNEDASEEAKKIVDDAKNFIERAIADIGKTSATKQLILGTASGWITGFISMXXXXXXXXX 333
           KN+  S +A K V DA + +   + D+ K     QL +G   G +TG+            
Sbjct: 6   KNDGGSGKAGKGVSDAIDTVLYYVVDLKKQQPMVQLGVGAGFGTVTGYFVTKGGRLVAAT 65

Query: 334 XXXXXXXXXXXSQKGYIDINWDKINKKVDXISDKIEKEATGKSPDWFEKVFVFVKSNSYY 513
                        KGYI +N  KI + +  +   +  + +GK          FV    + 
Sbjct: 66  VGISFLLAQFAIHKGYITLNESKIERDMKNLHKSVMNKVSGKKV--INISDSFVSEYRWI 123

Query: 514 SAGFTGGFLFGIA 552
             GF  G L G +
Sbjct: 124 LGGFAAGMLIGFS 136


>UniRef50_Q54Z98 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 226

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 25/94 (26%), Positives = 37/94 (39%)
 Frame = +1

Query: 265 LGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKINKKVDXISDKIEK 444
           +G A G+  G  +                     S KGYI + WDK++++    S K  K
Sbjct: 136 MGGALGYCCGIATRKIGTMVLVFVGAIFIVVQLLSSKGYIVVKWDKVSEE---HSPKFTK 192

Query: 445 EATGKSPDWFEKVFVFVKSNSYYSAGFTGGFLFG 546
           E   K   +    +  + SN  +  GF  GFL G
Sbjct: 193 E---KRRQYIRSFYNLLTSNLPFKVGFGSGFLLG 223


>UniRef50_Q23UD5 Cluster: FUN14 family protein; n=1; Tetrahymena
           thermophila SB210|Rep: FUN14 family protein -
           Tetrahymena thermophila SB210
          Length = 131

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 22/102 (21%), Positives = 38/102 (37%), Gaps = 2/102 (1%)
 Frame = +1

Query: 253 KQLILGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKINKKVDXIS- 429
           K+   G+  G+  G+ S                     S KGYI +N DKI + +   + 
Sbjct: 26  KEFTAGSVFGFCAGYFSRNAVKYAAFVTGGAFIFLQILSHKGYITMNMDKIEEDLKNAAD 85

Query: 430 -DKIEKEATGKSPDWFEKVFVFVKSNSYYSAGFTGGFLFGIA 552
            D   K  T  +    +K+   +      +AGF   +  G++
Sbjct: 86  LDGDGKLTTNDAKVGLKKLLSIIGDKVPNAAGFVAAYFLGLS 127


>UniRef50_UPI00006CE593 Cluster: hypothetical protein
           TTHERM_00145330; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00145330 - Tetrahymena
           thermophila SB210
          Length = 135

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 25/111 (22%), Positives = 46/111 (41%), Gaps = 5/111 (4%)
 Frame = +1

Query: 229 DIGKTSATKQLILGTASGWITGFISMXXXXXXXXXXXXXXXXXXXXSQKGYIDINWDKIN 408
           ++ K +  ++L LGT  G+ +G  +                     S +GY+++ W+K+ 
Sbjct: 22  NLHKQATAQELTLGTVFGYCSGAFTRRMARVGTFISGGLFVTAQLLSFQGYVNVEWNKME 81

Query: 409 ----KKVDXISD-KIEKEATGKSPDWFEKVFVFVKSNSYYSAGFTGGFLFG 546
               K +D   D KI+ +        ++K    ++     S GF  GFL G
Sbjct: 82  QDAIKALDQNGDNKIDMQ---DFKIMYDKYLSTLQYRLPSSTGFAAGFLLG 129


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 476,172,776
Number of Sequences: 1657284
Number of extensions: 7497154
Number of successful extensions: 20298
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 19790
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 20266
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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