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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fe100P01_F_G05
         (649 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9I9M5 Cluster: Frizzled-1 precursor; n=14; Eumetazoa|R...   113   3e-24
UniRef50_Q16JZ8 Cluster: Putative uncharacterized protein; n=2; ...   109   6e-23
UniRef50_Q9UP38 Cluster: Frizzled-1 precursor; n=86; Eumetazoa|R...   106   4e-22
UniRef50_Q4S970 Cluster: Chromosome 3 SCAF14700, whole genome sh...   105   7e-22
UniRef50_P18537 Cluster: Frizzled precursor; n=9; Diptera|Rep: F...   105   9e-22
UniRef50_Q5TPW4 Cluster: ENSANGP00000027735; n=1; Anopheles gamb...   101   1e-20
UniRef50_O16147 Cluster: Mom-5 protein; n=2; Caenorhabditis|Rep:...    99   1e-19
UniRef50_Q4SDD9 Cluster: Chromosome 3 SCAF14639, whole genome sh...    95   2e-18
UniRef50_Q4H315 Cluster: Frizzled receptor; n=1; Ciona intestina...    90   4e-17
UniRef50_UPI000065ECB7 Cluster: Frizzled-3 precursor (Fz-3) (hFz...    84   2e-15
UniRef50_A7SCF4 Cluster: Predicted protein; n=1; Nematostella ve...    81   2e-14
UniRef50_Q7QDV6 Cluster: ENSANGP00000024916; n=3; Endopterygota|...    79   7e-14
UniRef50_UPI000065D8E2 Cluster: Frizzled-3 precursor (Fz-3) (hFz...    79   1e-13
UniRef50_Q9VVX3 Cluster: Frizzled-2 precursor; n=3; Diptera|Rep:...    79   1e-13
UniRef50_UPI0000F1E04C Cluster: PREDICTED: similar to Frizzled X...    78   2e-13
UniRef50_Q9ULV1 Cluster: Frizzled-4 precursor; n=22; Euteleostom...    77   4e-13
UniRef50_UPI000065F60A Cluster: Homolog of Gallus gallus "Frizzl...    76   6e-13
UniRef50_Q589S5 Cluster: Frizzled receptor; n=1; Dugesia japonic...    76   9e-13
UniRef50_UPI0000E7FF69 Cluster: PREDICTED: hypothetical protein;...    75   1e-12
UniRef50_UPI00015B43E3 Cluster: PREDICTED: similar to GA21999-PA...    75   2e-12
UniRef50_Q9PT62 Cluster: Frizzled-4 precursor; n=10; Eumetazoa|R...    75   2e-12
UniRef50_UPI000065D9D0 Cluster: Frizzled-5 precursor (Fz-5) (hFz...    74   3e-12
UniRef50_UPI00005A004E Cluster: PREDICTED: similar to Frizzled 8...    73   6e-12
UniRef50_Q9H461 Cluster: Frizzled-8 precursor; n=10; Theria|Rep:...    73   6e-12
UniRef50_UPI0000E495F0 Cluster: PREDICTED: similar to Frizzled-1...    73   8e-12
UniRef50_UPI00015B5F46 Cluster: PREDICTED: hypothetical protein;...    72   1e-11
UniRef50_O60353 Cluster: Frizzled-6 precursor; n=54; Euteleostom...    71   2e-11
UniRef50_Q13467 Cluster: Frizzled-5 precursor; n=38; Eumetazoa|R...    71   2e-11
UniRef50_Q16Z40 Cluster: Frizzled; n=2; Culicidae|Rep: Frizzled ...    71   3e-11
UniRef50_Q92765 Cluster: Secreted frizzled-related protein 3 pre...    71   3e-11
UniRef50_O00144 Cluster: Frizzled-9 precursor; n=56; Euteleostom...    69   7e-11
UniRef50_Q61089 Cluster: Frizzled-6 precursor; n=21; Euteleostom...    69   7e-11
UniRef50_Q9NBW1 Cluster: Frizzled-4 precursor; n=3; Sophophora|R...    69   7e-11
UniRef50_UPI0000E46D3A Cluster: PREDICTED: similar to Frzb-1; n=...    69   1e-10
UniRef50_Q3LAK2 Cluster: Frizzled receptor; n=3; Hydroida|Rep: F...    68   2e-10
UniRef50_Q9N532 Cluster: Abnormal cell migration protein 1, isof...    66   5e-10
UniRef50_Q4H3F9 Cluster: Frizzled receptor; n=1; Ciona intestina...    66   5e-10
UniRef50_Q3LTR6 Cluster: Frizzled homolog; n=3; Caenorhabditis|R...    66   5e-10
UniRef50_UPI0000D56D61 Cluster: PREDICTED: similar to Frizzled 4...    66   9e-10
UniRef50_Q94132 Cluster: Transmembrane receptor LIN-17; n=3; Cae...    66   9e-10
UniRef50_Q6FHJ7 Cluster: Secreted frizzled-related protein 4 pre...    66   9e-10
UniRef50_A1IKD6 Cluster: Frizzled5/8; n=1; Hydra magnipapillata|...    65   1e-09
UniRef50_UPI0001556504 Cluster: PREDICTED: similar to membrane-t...    64   3e-09
UniRef50_Q16SA2 Cluster: Transmembrane protease, serine; n=1; Ae...    64   3e-09
UniRef50_Q9Y5Q5 Cluster: Atrial natriuteric peptide-converting e...    64   4e-09
UniRef50_Q95P13 Cluster: Secreted frizzled-related protein precu...    63   6e-09
UniRef50_Q4T9V1 Cluster: Chromosome undetermined SCAF7488, whole...    61   3e-08
UniRef50_A7RPM4 Cluster: Predicted protein; n=1; Nematostella ve...    61   3e-08
UniRef50_UPI0000F2D00C Cluster: PREDICTED: hypothetical protein;...    59   8e-08
UniRef50_UPI0000DB7495 Cluster: PREDICTED: similar to Corin CG21...    59   8e-08
UniRef50_Q9BY79 Cluster: Membrane frizzled-related protein; n=15...    58   1e-07
UniRef50_Q504J9 Cluster: Szl protein; n=6; Euteleostomi|Rep: Szl...    58   2e-07
UniRef50_O77438 Cluster: Frizzled-3 precursor; n=3; Sophophora|R...    58   2e-07
UniRef50_UPI00004D1D0E Cluster: Membrane frizzled-related protei...    57   3e-07
UniRef50_A7SXA8 Cluster: Predicted protein; n=1; Nematostella ve...    57   3e-07
UniRef50_A1Z709 Cluster: CG2105-PB, isoform B; n=5; Diptera|Rep:...    57   3e-07
UniRef50_Q4H2U4 Cluster: Secreted frizzled-related protein; n=1;...    57   4e-07
UniRef50_A4UAH3 Cluster: Frizzled receptor 3; n=2; Eukaryota|Rep...    56   7e-07
UniRef50_Q9GUF5 Cluster: Putative uncharacterized protein; n=2; ...    56   1e-06
UniRef50_Q9W3H0 Cluster: CG1632-PA; n=5; Diptera|Rep: CG1632-PA ...    55   1e-06
UniRef50_Q5J0Z5 Cluster: LIN-17; n=1; Pristionchus pacificus|Rep...    55   1e-06
UniRef50_Q4RYT0 Cluster: Chromosome 16 SCAF14974, whole genome s...    55   2e-06
UniRef50_Q4H3G0 Cluster: Frizzled receptor; n=2; Ciona|Rep: Friz...    55   2e-06
UniRef50_Q96HF1 Cluster: Secreted frizzled-related protein 2 pre...    53   7e-06
UniRef50_Q9NL45 Cluster: Frizzled homolog; n=2; Ciona intestinal...    52   2e-05
UniRef50_Q4H2U3 Cluster: Secreted frizzled-related protein; n=1;...    52   2e-05
UniRef50_Q8JHC7 Cluster: Secreted frizzled-related protein; n=1;...    51   2e-05
UniRef50_Q4H2U5 Cluster: Secreted frizzled-related protein; n=1;...    51   3e-05
UniRef50_Q4SF65 Cluster: Chromosome undetermined SCAF14608, whol...    50   4e-05
UniRef50_Q16VN8 Cluster: Putative uncharacterized protein; n=1; ...    50   4e-05
UniRef50_A1IKD5 Cluster: Frizzled4/9/10; n=1; Hydra magnipapilla...    50   4e-05
UniRef50_Q90ZA6 Cluster: Axszl; n=5; Euteleostomi|Rep: Axszl - A...    50   5e-05
UniRef50_O42397 Cluster: Crescent; n=7; Euteleostomi|Rep: Cresce...    48   1e-04
UniRef50_UPI0000DB76D0 Cluster: PREDICTED: similar to CG1632-PA;...    48   2e-04
UniRef50_UPI00015B523C Cluster: PREDICTED: similar to conserved ...    48   3e-04
UniRef50_Q0IHH5 Cluster: Putative uncharacterized protein; n=1; ...    48   3e-04
UniRef50_UPI0000E20752 Cluster: PREDICTED: hypothetical protein;...    47   3e-04
UniRef50_Q66K79 Cluster: Carboxypeptidase Z precursor; n=26; Eut...    47   3e-04
UniRef50_A7RPS6 Cluster: Predicted protein; n=1; Nematostella ve...    46   6e-04
UniRef50_Q8JFF5 Cluster: Type XVIII collagen long variant; n=2; ...    46   0.001
UniRef50_UPI0000E48FF8 Cluster: PREDICTED: similar to fibropelli...    45   0.001
UniRef50_Q4H2U2 Cluster: Secreted frizzled-related protein; n=1;...    45   0.001
UniRef50_Q5VKN1 Cluster: Frizzled-8; n=2; Elopocephala|Rep: Friz...    44   0.002
UniRef50_UPI0000588F3D Cluster: PREDICTED: similar to secreted f...    44   0.003
UniRef50_UPI00005A0542 Cluster: PREDICTED: similar to carboxypep...    43   0.006
UniRef50_UPI0000E47712 Cluster: PREDICTED: similar to echinonect...    42   0.010
UniRef50_UPI0000D9C447 Cluster: PREDICTED: similar to secreted f...    42   0.010
UniRef50_Q5T4F7 Cluster: Secreted frizzled-related protein 5 pre...    42   0.010
UniRef50_A7SA89 Cluster: Predicted protein; n=1; Nematostella ve...    42   0.013
UniRef50_UPI0000F33F4D Cluster: UPI0000F33F4D related cluster; n...    41   0.022
UniRef50_Q2PBM7 Cluster: Long form of collagen XVIII alpha 1 cha...    40   0.039
UniRef50_UPI0000E48747 Cluster: PREDICTED: similar to protease, ...    39   0.091
UniRef50_P39060 Cluster: Collagen alpha-1(XVIII) chain precursor...    39   0.091
UniRef50_Q5YGP6 Cluster: Blue pigment protein precursor; n=1; Rh...    39   0.12 
UniRef50_Q4RMT0 Cluster: Chromosome 3 SCAF15018, whole genome sh...    38   0.21 
UniRef50_Q70LH3 Cluster: Frizzled receptor; n=1; Suberites domun...    38   0.28 
UniRef50_UPI0000E48793 Cluster: PREDICTED: similar to egg bindin...    37   0.48 
UniRef50_UPI0001554ED1 Cluster: PREDICTED: similar to type XVIII...    36   0.84 
UniRef50_A7S829 Cluster: Predicted protein; n=2; Nematostella ve...    36   0.84 
UniRef50_UPI0000E48E51 Cluster: PREDICTED: similar to human ente...    33   4.5  
UniRef50_Q5E034 Cluster: Superfamily I DNA helicases and helicas...    33   4.5  
UniRef50_UPI0000E45FA6 Cluster: PREDICTED: hypothetical protein;...    33   6.0  

>UniRef50_Q9I9M5 Cluster: Frizzled-1 precursor; n=14; Eumetazoa|Rep:
           Frizzled-1 precursor - Xenopus laevis (African clawed
           frog)
          Length = 559

 Score =  113 bits (273), Expect = 3e-24
 Identities = 50/104 (48%), Positives = 68/104 (65%)
 Frame = +3

Query: 312 IIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQED 491
           +I SLL    L+   +    +G S+P HG C+PI+I  C  + YNQTI PN+L    QED
Sbjct: 21  LILSLLLSVCLSVEGQYNGEKGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQED 80

Query: 492 AAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCTILDSAIPPWSS 623
           A   +  F  L+K+ CSP+L+FFLCS+YAPVCT+L+ A+PP  S
Sbjct: 81  AGLEVHQFYPLVKVQCSPELKFFLCSIYAPVCTVLEQALPPCRS 124


>UniRef50_Q16JZ8 Cluster: Putative uncharacterized protein; n=2;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 276

 Score =  109 bits (262), Expect = 6e-23
 Identities = 51/127 (40%), Positives = 76/127 (59%), Gaps = 5/127 (3%)
 Frame = +3

Query: 276 MINMAKFWKHYVIIFSLLCLFALTK-----GSRXIVYQGDSLPQHGRCEPITIQFCQKLR 440
           M  +A  +K++V++  L    ++ +     G        D    H RCE ITI FC  ++
Sbjct: 1   MAKLAMLFKYFVLMLCLASSGSIQQQESFGGHEMSSMNADDFQHHNRCETITIPFCTDIQ 60

Query: 441 YNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCTILDSAIPPWS 620
           YN+TI PN++   +QE+AA  +  F  L+K++CSPDL+FFLC++YAPVCTIL+  IPP  
Sbjct: 61  YNRTIMPNLIGHTKQEEAALEVHQFIPLVKIDCSPDLKFFLCTLYAPVCTILNYPIPPCR 120

Query: 621 SFM*SCK 641
           S   S +
Sbjct: 121 SLCESAR 127


>UniRef50_Q9UP38 Cluster: Frizzled-1 precursor; n=86; Eumetazoa|Rep:
           Frizzled-1 precursor - Homo sapiens (Human)
          Length = 647

 Score =  106 bits (255), Expect = 4e-22
 Identities = 44/84 (52%), Positives = 59/84 (70%)
 Frame = +3

Query: 372 QGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDL 551
           +G S+P HG C+PI+I  C  + YNQTI PN+L    QEDA   +  F  L+K+ CS +L
Sbjct: 106 RGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAEL 165

Query: 552 RFFLCSVYAPVCTILDSAIPPWSS 623
           +FFLCS+YAPVCT+L+ A+PP  S
Sbjct: 166 KFFLCSMYAPVCTVLEQALPPCRS 189


>UniRef50_Q4S970 Cluster: Chromosome 3 SCAF14700, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 3 SCAF14700, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 456

 Score =  105 bits (253), Expect = 7e-22
 Identities = 52/111 (46%), Positives = 69/111 (62%), Gaps = 1/111 (0%)
 Frame = +3

Query: 294 FWKHYVIIFSL-LCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNIL 470
           F K +++ F L L + A   G   IV     +P HG C+ ITI  C  + YNQTI PN++
Sbjct: 3   FCKTWIVAFLLPLLVTAQYHGDNGIV-----VPDHGFCQQITIPLCTDIAYNQTIMPNLV 57

Query: 471 NQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCTILDSAIPPWSS 623
               QEDA   +  F  L+K+ CSP+L+FFLCS+YAPVCT+L+ AIPP  S
Sbjct: 58  GHYNQEDAGLEVHQFYPLVKVQCSPELKFFLCSMYAPVCTVLEKAIPPCRS 108


>UniRef50_P18537 Cluster: Frizzled precursor; n=9; Diptera|Rep:
           Frizzled precursor - Drosophila melanogaster (Fruit fly)
          Length = 581

 Score =  105 bits (252), Expect = 9e-22
 Identities = 44/88 (50%), Positives = 57/88 (64%)
 Frame = +3

Query: 378 DSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRF 557
           D LP H RCEPITI  C+ + YN TI PN++   +QE+A   +  F  L+K+ CS DL+ 
Sbjct: 45  DGLPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQL 104

Query: 558 FLCSVYAPVCTILDSAIPPWSSFM*SCK 641
           FLCS+Y PVCTIL+  IPP  S   S +
Sbjct: 105 FLCSLYVPVCTILERPIPPCRSLCESAR 132


>UniRef50_Q5TPW4 Cluster: ENSANGP00000027735; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000027735 - Anopheles gambiae
           str. PEST
          Length = 254

 Score =  101 bits (243), Expect = 1e-20
 Identities = 44/89 (49%), Positives = 58/89 (65%)
 Frame = +3

Query: 375 GDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLR 554
           G+    H RCEPITI FC  + YN+TI PN     +Q++AA  +  +  L+K++CSPDL+
Sbjct: 31  GEEFQHHNRCEPITIPFCIGIPYNRTIMPNRFGHTKQDEAALEVHQYVPLVKIDCSPDLK 90

Query: 555 FFLCSVYAPVCTILDSAIPPWSSFM*SCK 641
           FFLC +YAPVCTIL   IPP  S   S +
Sbjct: 91  FFLCLLYAPVCTILPFPIPPCRSLCESAR 119


>UniRef50_O16147 Cluster: Mom-5 protein; n=2; Caenorhabditis|Rep:
           Mom-5 protein - Caenorhabditis elegans
          Length = 568

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 47/114 (41%), Positives = 64/114 (56%)
 Frame = +3

Query: 300 KHYVIIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQA 479
           +H +I+F   CL A  + S   +   +      +CE ITI  C+ L YNQT+FPN+L   
Sbjct: 3   RHILILFLFGCLSADQRLSSTSISSMNGFSTTRKCEHITIPMCKNLDYNQTVFPNLLGHT 62

Query: 480 RQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCTILDSAIPPWSSFM*SCK 641
            Q +A   +  F  LIK+ CS D+R FLC+VYAPVCT+L+  I P      S K
Sbjct: 63  TQSEAGPAIAQFNPLIKVKCSEDIRLFLCTVYAPVCTVLEKPIQPCRELCLSAK 116


>UniRef50_Q4SDD9 Cluster: Chromosome 3 SCAF14639, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 3 SCAF14639, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 459

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 40/76 (52%), Positives = 53/76 (69%)
 Frame = +3

Query: 396 GRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVY 575
           G C+PI+I  C  + YNQTI PN+L    Q++A   +  F  L+++ CS +LRFFLCS+Y
Sbjct: 7   GSCQPISIPLCTHIAYNQTIMPNLLGHRGQDEAGLEVHQFYPLVEVRCSSELRFFLCSLY 66

Query: 576 APVCTILDSAIPPWSS 623
           APVCT+LD AIPP  S
Sbjct: 67  APVCTLLDRAIPPCRS 82


>UniRef50_Q4H315 Cluster: Frizzled receptor; n=1; Ciona
           intestinalis|Rep: Frizzled receptor - Ciona intestinalis
           (Transparent sea squirt)
          Length = 581

 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 38/76 (50%), Positives = 51/76 (67%), Gaps = 1/76 (1%)
 Frame = +3

Query: 390 QH-GRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLC 566
           QH G+CEPIT+  C+ ++YN TIFPNIL    Q +A   +  F  L+K+ CSP L+ FLC
Sbjct: 26  QHEGKCEPITLSICKGIQYNVTIFPNILGHQDQSEAGLQLNQFYPLVKVGCSPTLQLFLC 85

Query: 567 SVYAPVCTILDSAIPP 614
           SVY P+C+  + A PP
Sbjct: 86  SVYTPICSTYNRAFPP 101


>UniRef50_UPI000065ECB7 Cluster: Frizzled-3 precursor (Fz-3)
           (hFz3).; n=1; Takifugu rubripes|Rep: Frizzled-3
           precursor (Fz-3) (hFz3). - Takifugu rubripes
          Length = 634

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 36/63 (57%), Positives = 44/63 (69%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPIT++ CQ L YN T  PN+LN   Q+ AA  M  F  ++ L CSPDLR FLC++YAP
Sbjct: 32  CEPITLRMCQGLPYNATFMPNLLNHYDQQTAALAMEPFHPMVNLQCSPDLRMFLCALYAP 91

Query: 582 VCT 590
           VCT
Sbjct: 92  VCT 94


>UniRef50_A7SCF4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 603

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 41/90 (45%), Positives = 55/90 (61%)
 Frame = +3

Query: 321 SLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAA 500
           +L+ L  +T  +  +VY   S   + +C PITI  C  + YN T FPN L Q  QE+AA 
Sbjct: 7   ALILLLFITVSA--MVYGQRSEVPNSKCTPITIPLCMGIGYNATRFPNFLAQESQEEAAK 64

Query: 501 NMLLFTTLIKLNCSPDLRFFLCSVYAPVCT 590
            +  F  LI +NC+P LRFFLCSV+ P+CT
Sbjct: 65  RIHEFKPLIAVNCAPLLRFFLCSVFVPMCT 94


>UniRef50_Q7QDV6 Cluster: ENSANGP00000024916; n=3;
           Endopterygota|Rep: ENSANGP00000024916 - Anopheles
           gambiae str. PEST
          Length = 687

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 32/65 (49%), Positives = 44/65 (67%)
 Frame = +3

Query: 393 HGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSV 572
           + RCE ITI  C+ + YN T FPN +N   QE+A   +  F  L+++ CSPDL+FFLCS+
Sbjct: 63  NSRCEEITIPMCRGIGYNLTSFPNEMNHETQEEAGLEVHQFWPLVEIKCSPDLKFFLCSM 122

Query: 573 YAPVC 587
           Y P+C
Sbjct: 123 YTPIC 127


>UniRef50_UPI000065D8E2 Cluster: Frizzled-3 precursor (Fz-3)
           (hFz3).; n=1; Takifugu rubripes|Rep: Frizzled-3
           precursor (Fz-3) (hFz3). - Takifugu rubripes
          Length = 717

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 34/74 (45%), Positives = 44/74 (59%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPI ++ CQ L YN T  PN+L+   Q+ AA  M  F  ++ L CSPDLR FLC++Y P
Sbjct: 9   CEPIRLRMCQDLPYNTTFMPNLLHHYDQQTAALAMEPFHPMVNLECSPDLRMFLCALYTP 68

Query: 582 VCTILDSAIPPWSS 623
           VC +      P  S
Sbjct: 69  VCVVYGQVSMPCRS 82


>UniRef50_Q9VVX3 Cluster: Frizzled-2 precursor; n=3; Diptera|Rep:
           Frizzled-2 precursor - Drosophila melanogaster (Fruit
           fly)
          Length = 694

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 31/63 (49%), Positives = 43/63 (68%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           RCE ITI  C+ + YN T FPN +N   Q++A   +  F  L+++ CSPDL+FFLCS+Y 
Sbjct: 63  RCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYT 122

Query: 579 PVC 587
           P+C
Sbjct: 123 PIC 125


>UniRef50_UPI0000F1E04C Cluster: PREDICTED: similar to Frizzled X
           isoform 1; n=3; Euteleostomi|Rep: PREDICTED: similar to
           Frizzled X isoform 1 - Danio rerio
          Length = 561

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 396 GRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVY 575
           G+CEPITI  CQ + YN T  PN+LN   QE+A+  +  F  L+K  C   L+FFLCS+Y
Sbjct: 34  GKCEPITIPMCQGIGYNMTRMPNLLNYESQEEASIKLNEFAPLVKYGCDIHLQFFLCSLY 93

Query: 576 APVCTILDSAIPP 614
            P+C    SA  P
Sbjct: 94  VPMCAEQVSASIP 106


>UniRef50_Q9ULV1 Cluster: Frizzled-4 precursor; n=22;
           Euteleostomi|Rep: Frizzled-4 precursor - Homo sapiens
           (Human)
          Length = 537

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 33/64 (51%), Positives = 40/64 (62%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           RC+PI I  CQ L YN T  PN++    Q DA   +  FT LI+  CS  L+FFLCSVY 
Sbjct: 44  RCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYV 103

Query: 579 PVCT 590
           P+CT
Sbjct: 104 PMCT 107


>UniRef50_UPI000065F60A Cluster: Homolog of Gallus gallus "Frizzled
           1 precursor (Frizzled-1) (Fz-1) (cFz-1).; n=1; Takifugu
           rubripes|Rep: Homolog of Gallus gallus "Frizzled 1
           precursor (Frizzled-1) (Fz-1) (cFz-1). - Takifugu
           rubripes
          Length = 582

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 35/71 (49%), Positives = 43/71 (60%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+ ITI FC+ L Y  TI PNIL    Q+DA+  +  F  LI   CSPD++ FLCSVY P
Sbjct: 144 CQAITIPFCKDLPYTHTILPNILGHKNQDDASLEVHTFAPLIHAGCSPDMKPFLCSVYTP 203

Query: 582 VCTILDSAIPP 614
            C +L    PP
Sbjct: 204 EC-VLGKPRPP 213



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 31/62 (50%), Positives = 38/62 (61%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPIT+  CQ L YNQTI PN+L    Q +A   M  F  +++  CS D+R FLC VY P
Sbjct: 380 CEPITVPLCQGLPYNQTITPNLLGHTSQREAMMKMSFFNGIVQTVCSEDIRLFLCMVYVP 439

Query: 582 VC 587
            C
Sbjct: 440 RC 441



 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 32/62 (51%), Positives = 38/62 (61%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+PIT+  C  L Y +TI PNIL    QE+A   M  F  LIK++CS  LR FLCS Y P
Sbjct: 262 CQPITLSLCNDLPYTETILPNILGHRTQEEAGLQMHQFVPLIKVDCSAHLRTFLCSAYTP 321

Query: 582 VC 587
            C
Sbjct: 322 KC 323



 Score = 34.3 bits (75), Expect = 2.6
 Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
 Frame = +3

Query: 381 SLPQHGRCEPITIQFCQKLRYNQTIFPN-ILNQARQEDAAANMLLFTTLIKLNCSPDLRF 557
           S  +   C+P T  FCQ + Y  + +P+  L  + Q+           +++ NCSP +  
Sbjct: 20  STAKRDNCKPFTASFCQGMGYTTSPYPSGALGYSLQQ--------IGQMVESNCSPGIAT 71

Query: 558 FLCSVYAPVC 587
            +C    P C
Sbjct: 72  LMCRTAVPEC 81


>UniRef50_Q589S5 Cluster: Frizzled receptor; n=1; Dugesia
           japonica|Rep: Frizzled receptor - Dugesia japonica
           (Planarian)
          Length = 722

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           RCE + +  C+ L YN+T  PN+ N   QE+A      F  L+ + CSPDL FFLCS+Y 
Sbjct: 35  RCEDLVMPLCRGLWYNRTRMPNMFNHETQEEAGHQAQQFMYLVTIKCSPDLHFFLCSIYT 94

Query: 579 PVCT-ILDSAIPPWSS 623
           P+C    D  +PP  S
Sbjct: 95  PICVENYDKPLPPCRS 110


>UniRef50_UPI0000E7FF69 Cluster: PREDICTED: hypothetical protein;
           n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
           - Gallus gallus
          Length = 709

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 31/62 (50%), Positives = 39/62 (62%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPITI  C ++ YN T FPNI+    Q+ AA  M  F TL+ L+CSPD+  FLC  + P
Sbjct: 25  CEPITISRCSRMPYNMTFFPNIMGHYDQDTAALQMEPFLTLMNLHCSPDVHTFLCKAFVP 84

Query: 582 VC 587
            C
Sbjct: 85  AC 86


>UniRef50_UPI00015B43E3 Cluster: PREDICTED: similar to GA21999-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA21999-PA - Nasonia vitripennis
          Length = 641

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 32/69 (46%), Positives = 43/69 (62%)
 Frame = +3

Query: 381 SLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFF 560
           S P   RCE ITI  C+ + YN T  PN LN   Q++A   +  F  L+++ CS DL+FF
Sbjct: 53  SSPTGSRCEEITIPMCKGIGYNLTTMPNELNHDTQDEAGLEVHQFWPLVEIKCSLDLKFF 112

Query: 561 LCSVYAPVC 587
           LCS+Y P+C
Sbjct: 113 LCSMYTPIC 121


>UniRef50_Q9PT62 Cluster: Frizzled-4 precursor; n=10; Eumetazoa|Rep:
           Frizzled-4 precursor - Xenopus laevis (African clawed
           frog)
          Length = 523

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 32/63 (50%), Positives = 39/63 (61%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+PI I  CQ L YN T  PN++    Q DA   +  FT LI+  CS  L+FFLCSVY P
Sbjct: 31  CDPIRITMCQNLGYNVTKMPNLVGHELQADAELQLTTFTPLIQYGCSSQLQFFLCSVYVP 90

Query: 582 VCT 590
           +CT
Sbjct: 91  MCT 93


>UniRef50_UPI000065D9D0 Cluster: Frizzled-5 precursor (Fz-5) (hFz5)
           (FzE5).; n=2; Euteleostomi|Rep: Frizzled-5 precursor
           (Fz-5) (hFz5) (FzE5). - Takifugu rubripes
          Length = 422

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 29/62 (46%), Positives = 39/62 (62%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPIT+  C+ + YN T  PN  N   QE+    +  F  L+++ CSPDL FFLCS+Y P
Sbjct: 1   CEPITVPMCKDIGYNLTYMPNQFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTP 60

Query: 582 VC 587
           +C
Sbjct: 61  IC 62


>UniRef50_UPI00005A004E Cluster: PREDICTED: similar to Frizzled 8
           precursor (Frizzled-8) (Fz-8) (mFz8); n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to Frizzled 8
           precursor (Frizzled-8) (Fz-8) (mFz8) - Canis familiaris
          Length = 613

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 34/97 (35%), Positives = 52/97 (53%)
 Frame = +3

Query: 297 WKHYVIIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQ 476
           W + + + SLL   AL + S           +   C+ IT+  C+ + YN T  PN  N 
Sbjct: 111 WGYLLEVTSLLAALALLQRSSGAAAAS---AKELACQEITVPLCKGIGYNYTYMPNQFNH 167

Query: 477 ARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
             Q++A   +  F  L+++ CSPDL+FFLCS+Y P+C
Sbjct: 168 DTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPIC 204


>UniRef50_Q9H461 Cluster: Frizzled-8 precursor; n=10; Theria|Rep:
           Frizzled-8 precursor - Homo sapiens (Human)
          Length = 694

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 34/97 (35%), Positives = 52/97 (53%)
 Frame = +3

Query: 297 WKHYVIIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQ 476
           W + + + SLL   AL + S           +   C+ IT+  C+ + YN T  PN  N 
Sbjct: 3   WGYLLEVTSLLAALALLQRSSGAAAAS---AKELACQEITVPLCKGIGYNYTYMPNQFNH 59

Query: 477 ARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
             Q++A   +  F  L+++ CSPDL+FFLCS+Y P+C
Sbjct: 60  DTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPIC 96


>UniRef50_UPI0000E495F0 Cluster: PREDICTED: similar to Frizzled-10;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to Frizzled-10 - Strongylocentrotus purpuratus
          Length = 610

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 34/77 (44%), Positives = 46/77 (59%), Gaps = 1/77 (1%)
 Frame = +3

Query: 396 GRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVY 575
           G CE ITI FCQ + YN T  PN+     Q +AA ++  F  L+ + C+  LR FLCS+Y
Sbjct: 32  GHCERITIDFCQGIGYNMTKMPNLFGHVTQSEAAPSIHEFHPLVVVGCAEHLRLFLCSMY 91

Query: 576 APVCT-ILDSAIPPWSS 623
           AP+C+  +D  IP   S
Sbjct: 92  APMCSEHIDIRIPSCQS 108


>UniRef50_UPI00015B5F46 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 573

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 38/99 (38%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
 Frame = +3

Query: 300 KHYVIIFSLLCLFALTKGSRX--IVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILN 473
           K ++++   L L  LT  +R   + +QG S     +CE + + FC+ LRYN T  PN + 
Sbjct: 5   KMFLLLRFGLVLVGLTGSARSWGLNHQGSS----AKCERLNVSFCRGLRYNLTAMPNFMG 60

Query: 474 QARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCT 590
              Q  A   +     L+  NCS  LRFFLCSV+APVC+
Sbjct: 61  HEDQLQAERELAKLMPLVHYNCSRHLRFFLCSVFAPVCS 99


>UniRef50_O60353 Cluster: Frizzled-6 precursor; n=54;
           Euteleostomi|Rep: Frizzled-6 precursor - Homo sapiens
           (Human)
          Length = 706

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 30/71 (42%), Positives = 38/71 (53%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPIT+  C K+ YN T FPN++    Q  AA  M  F  L  L CSP++  FLC  + P
Sbjct: 24  CEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVP 83

Query: 582 VCTILDSAIPP 614
            C      +PP
Sbjct: 84  TCIEQIHVVPP 94


>UniRef50_Q13467 Cluster: Frizzled-5 precursor; n=38; Eumetazoa|Rep:
           Frizzled-5 precursor - Homo sapiens (Human)
          Length = 585

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 28/62 (45%), Positives = 40/62 (64%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+ IT+  C+ + YN T  PN  N   Q++A   +  F  L+++ CSPDLRFFLCS+Y P
Sbjct: 33  CQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTP 92

Query: 582 VC 587
           +C
Sbjct: 93  IC 94


>UniRef50_Q16Z40 Cluster: Frizzled; n=2; Culicidae|Rep: Frizzled -
           Aedes aegypti (Yellowfever mosquito)
          Length = 582

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 28/63 (44%), Positives = 40/63 (63%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPI I+ C+ + YN+T  PN++    Q DA   +  F+ LI+  CS  L+FFLC+ Y P
Sbjct: 34  CEPIRIELCRGIGYNETSLPNLVGHELQTDADFTLQTFSPLIQYGCSKQLKFFLCAAYVP 93

Query: 582 VCT 590
           +CT
Sbjct: 94  MCT 96


>UniRef50_Q92765 Cluster: Secreted frizzled-related protein 3
           precursor; n=30; Euteleostomi|Rep: Secreted
           frizzled-related protein 3 precursor - Homo sapiens
           (Human)
          Length = 325

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 30/64 (46%), Positives = 42/64 (65%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEP+ I  C+ L +N T  PN L+ + Q +A   +  F  L+  +CSPDL FFLC++YAP
Sbjct: 35  CEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAP 94

Query: 582 VCTI 593
           +CTI
Sbjct: 95  ICTI 98


>UniRef50_O00144 Cluster: Frizzled-9 precursor; n=56;
           Euteleostomi|Rep: Frizzled-9 precursor - Homo sapiens
           (Human)
          Length = 591

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 31/72 (43%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
 Frame = +3

Query: 387 PQHGR----CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLR 554
           P+ GR    C+ + I  C+ + YN T  PN+L    Q +AAA +  F  L++  C   LR
Sbjct: 30  PERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLR 89

Query: 555 FFLCSVYAPVCT 590
           FFLCS+YAP+CT
Sbjct: 90  FFLCSLYAPMCT 101


>UniRef50_Q61089 Cluster: Frizzled-6 precursor; n=21;
           Euteleostomi|Rep: Frizzled-6 precursor - Mus musculus
           (Mouse)
          Length = 709

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 29/63 (46%), Positives = 36/63 (57%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPIT+  C K+ YN T FPN++    Q  AA  M  F  L  L CSP++  FLC  + P
Sbjct: 24  CEPITVPRCMKMTYNMTFFPNLMGHYDQGIAAVEMGHFLHLANLECSPNIEMFLCQAFIP 83

Query: 582 VCT 590
            CT
Sbjct: 84  TCT 86


>UniRef50_Q9NBW1 Cluster: Frizzled-4 precursor; n=3; Sophophora|Rep:
           Frizzled-4 precursor - Drosophila melanogaster (Fruit
           fly)
          Length = 705

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 27/69 (39%), Positives = 41/69 (59%)
 Frame = +3

Query: 384 LPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFL 563
           +P   +CE I I+ C+K+ YN+T  PN++    Q D    +  F  LI+ +CS  L+ FL
Sbjct: 40  IPAFRQCETIRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFL 99

Query: 564 CSVYAPVCT 590
           C+ Y P+CT
Sbjct: 100 CAAYVPMCT 108


>UniRef50_UPI0000E46D3A Cluster: PREDICTED: similar to Frzb-1; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Frzb-1 - Strongylocentrotus purpuratus
          Length = 267

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+ + +  C+ + YN T  PN+L+ + QE+A   +  F  L+  NCS +L FFLC++Y P
Sbjct: 10  CQLVQLPMCESMPYNLTRMPNLLHHSTQENAKLAIEQFLPLVNTNCSGNLTFFLCAMYVP 69

Query: 582 VCTI--LDSAIPPWSS 623
           +CT+  ++  +PP  S
Sbjct: 70  ICTMGFMEEPVPPCKS 85


>UniRef50_Q3LAK2 Cluster: Frizzled receptor; n=3; Hydroida|Rep:
           Frizzled receptor - Hydractinia echinata (Snail fur)
           (Hermit crab hydroid)
          Length = 560

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 31/67 (46%), Positives = 43/67 (64%), Gaps = 1/67 (1%)
 Frame = +3

Query: 417 IQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCTIL 596
           ++ CQ L YN T+FPN L     E+A+  +  F  L+K+ C+ ++ FFLCSVY PVC  L
Sbjct: 38  LRLCQNLGYNATMFPNSLEHRNMENASTELDNFLPLVKIRCAKEIEFFLCSVYLPVC--L 95

Query: 597 DSA-IPP 614
           DS  +PP
Sbjct: 96  DSGPLPP 102


>UniRef50_Q9N532 Cluster: Abnormal cell migration protein 1, isoform
           b; n=3; Caenorhabditis|Rep: Abnormal cell migration
           protein 1, isoform b - Caenorhabditis elegans
          Length = 529

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 26/63 (41%), Positives = 42/63 (66%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           RC+ +  + C  L YN T FPN++++   +DA+ ++L +  L+ + CS  L+FFLCSVY 
Sbjct: 25  RCQKVDHEMCNDLPYNLTSFPNLVDEESWKDASESILTYKPLLSVVCSEQLKFFLCSVYF 84

Query: 579 PVC 587
           P+C
Sbjct: 85  PMC 87


>UniRef50_Q4H3F9 Cluster: Frizzled receptor; n=1; Ciona
           intestinalis|Rep: Frizzled receptor - Ciona intestinalis
           (Transparent sea squirt)
          Length = 602

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 28/63 (44%), Positives = 38/63 (60%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           RCEPI I+ CQ L YN T  PN   Q RQ +A   +  +  L++ NCS +L  FLC+ + 
Sbjct: 55  RCEPIQIKMCQGLGYNATRMPNRFGQYRQTEAGIELNSYQVLLQYNCSSELPMFLCAAFL 114

Query: 579 PVC 587
           P+C
Sbjct: 115 PMC 117


>UniRef50_Q3LTR6 Cluster: Frizzled homolog; n=3; Caenorhabditis|Rep:
           Frizzled homolog - Caenorhabditis elegans
          Length = 578

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 26/63 (41%), Positives = 39/63 (61%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           +CE ITI  C+ + YN T FPN     +QE+A   +  F  L+++ C   L+FFLC++Y 
Sbjct: 24  KCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCTMYT 83

Query: 579 PVC 587
           P+C
Sbjct: 84  PIC 86


>UniRef50_UPI0000D56D61 Cluster: PREDICTED: similar to Frizzled 4
           precursor (Frizzled-4) (Fz-4) (mFz4); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Frizzled 4
           precursor (Frizzled-4) (Fz-4) (mFz4) - Tribolium
           castaneum
          Length = 527

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 28/63 (44%), Positives = 37/63 (58%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CEPI +  C  L YN T  PN+     Q++A   +  F+ LI+  CS  L+ FLCSVY P
Sbjct: 22  CEPIRVDMCTNLGYNMTEMPNLGGNDIQQEADYTLKSFSPLIQYGCSSQLKLFLCSVYVP 81

Query: 582 VCT 590
           +CT
Sbjct: 82  MCT 84


>UniRef50_Q94132 Cluster: Transmembrane receptor LIN-17; n=3;
           Caenorhabditis|Rep: Transmembrane receptor LIN-17 -
           Caenorhabditis elegans
          Length = 558

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 28/66 (42%), Positives = 38/66 (57%)
 Frame = +3

Query: 396 GRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVY 575
           G+C PI I+ C+ L YN T FPN +    Q     +   F  L+K  C P + FF+CSV+
Sbjct: 26  GKCIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVF 85

Query: 576 APVCTI 593
           AP+C I
Sbjct: 86  APMCPI 91


>UniRef50_Q6FHJ7 Cluster: Secreted frizzled-related protein 4
           precursor; n=27; Tetrapoda|Rep: Secreted
           frizzled-related protein 4 precursor - Homo sapiens
           (Human)
          Length = 346

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 31/76 (40%), Positives = 46/76 (60%), Gaps = 2/76 (2%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CE + I  C+ + +N T  PN L+ + QE+A   +  +  L+ +NCS  LRFFLC++YAP
Sbjct: 24  CEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLCAMYAP 83

Query: 582 VCTI--LDSAIPPWSS 623
           +CT+  L   I P  S
Sbjct: 84  ICTLEFLHDPIKPCKS 99


>UniRef50_A1IKD6 Cluster: Frizzled5/8; n=1; Hydra
           magnipapillata|Rep: Frizzled5/8 - Hydra magnipapillata
           (Hydra)
          Length = 525

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 34/92 (36%), Positives = 50/92 (54%)
 Frame = +3

Query: 312 IIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQED 491
           +I  LLCL  +    R I  + ++     +CE ++I  C+K+ YN T  PN      Q D
Sbjct: 13  VIIHLLCLNLIFCEPRGIRERYETR----KCEKLSITMCEKVGYNLTFMPNKHGHVNQID 68

Query: 492 AAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           A   +  F  L+ +NCSP L  F+CS+YAP+C
Sbjct: 69  AGQLIRQFAPLVAINCSPLLAHFVCSLYAPMC 100


>UniRef50_UPI0001556504 Cluster: PREDICTED: similar to membrane-type
           frizzled-related protein MFRP, partial; n=1;
           Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           membrane-type frizzled-related protein MFRP, partial -
           Ornithorhynchus anatinus
          Length = 347

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
 Frame = +3

Query: 387 PQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLL-FTTLIKLNCSPDLRFFL 563
           P    CEPI ++ CQ L YN T FP++      +  A N+L  FT+L  L C    R FL
Sbjct: 263 PLESVCEPIQVEVCQDLSYNGTAFPSVWMSLPDQQGAVNVLRDFTSLADLACYQPFRRFL 322

Query: 564 CSVYAPVCTILDSAIPP 614
           C +Y P C   +  +PP
Sbjct: 323 CGLYVPRCVPGEGVLPP 339


>UniRef50_Q16SA2 Cluster: Transmembrane protease, serine; n=1; Aedes
           aegypti|Rep: Transmembrane protease, serine - Aedes
           aegypti (Yellowfever mosquito)
          Length = 1290

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
 Frame = +3

Query: 378 DSLPQHGRCEPITIQFCQ--KLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDL 551
           D  P  G C P+ ++FCQ  K+ YN T+FPN +    Q +A   + LF  L+ + C   +
Sbjct: 699 DRNPAPGVCLPVIVKFCQQHKIPYNYTVFPNYIGHFGQPEAQMEIDLFEALVDVQCYELV 758

Query: 552 RFFLCSVYAPVCTILDSAIPPWSS 623
             FLCS++ P C    S + P  S
Sbjct: 759 PLFLCSLFVPKCGATGSTVTPCKS 782


>UniRef50_Q9Y5Q5 Cluster: Atrial natriuteric peptide-converting
           enzyme; n=34; Euteleostomi|Rep: Atrial natriuteric
           peptide-converting enzyme - Homo sapiens (Human)
          Length = 1042

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
 Frame = +3

Query: 351 GSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAAN--MLLFTTL 524
           G   +    +SL    +CEPIT++ C  L YN T +PN      Q++A+ +    LF  L
Sbjct: 438 GGSSLCDPNNSLNNCSQCEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPAL 497

Query: 525 IKLNCSPDLRFFLCSVYAPVCTI-LDSAIPP 614
           ++ NC   L FF C++  P C +     IPP
Sbjct: 498 VQTNCYKYLMFFSCTILVPKCDVNTGERIPP 528



 Score = 37.9 bits (84), Expect = 0.21
 Identities = 21/64 (32%), Positives = 32/64 (50%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C  IT   CQ L Y+ T+ P +L+  R  +    +  FT L +L+C   +  F C++  P
Sbjct: 139 CMNITHSQCQMLPYHATLTP-LLSVVRNMEMEKFLKFFTYLHRLSCYQHIMLFGCTLAFP 197

Query: 582 VCTI 593
            C I
Sbjct: 198 ECII 201


>UniRef50_Q95P13 Cluster: Secreted frizzled-related protein precusor
           precursor; n=5; Strongylocentrotus purpuratus|Rep:
           Secreted frizzled-related protein precusor precursor -
           Strongylocentrotus purpuratus (Purple sea urchin)
          Length = 920

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 27/63 (42%), Positives = 38/63 (60%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CE ++   C  ++Y+ T FPN+L  A Q+ A   +  F  LI++ CS DL  FLC+VY P
Sbjct: 398 CESVSTPICMDMKYDFTQFPNLLQHANQDVAYLELSQFAPLIQVECSLDLGAFLCAVYMP 457

Query: 582 VCT 590
            CT
Sbjct: 458 PCT 460



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
 Frame = +3

Query: 297 WKHYVIIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQK--LRYNQTIFPNIL 470
           W   +++F+++      + S  +V  G S      CEP+T+  C +  ++Y +TIFPN+ 
Sbjct: 11  WLASMLVFTVVTGQPPLQNSSSVVVGGRST-----CEPLTMPLCLQNGVQYTETIFPNLA 65

Query: 471 NQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC-TILDSAIP 611
               Q+DA         L+ + C P +  F+C+++AP C  + D ++P
Sbjct: 66  GMMTQQDAIVASESLAPLVAIGCGP-IVDFVCTLFAPPCLEVGDVSVP 112



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 22/62 (35%), Positives = 32/62 (51%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C  +T+  C+++ +  T FPNI      E+ A +M   T LI   CS DL   +C+ Y P
Sbjct: 184 CYDVTVPECRQMGFTHTKFPNIFGHTTPEEMAQDMTSLTGLILSGCSDDLLPLICAAYLP 243

Query: 582 VC 587
            C
Sbjct: 244 KC 245



 Score = 39.5 bits (88), Expect = 0.069
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
 Frame = +3

Query: 381 SLPQHGRCEPITIQFCQK-LRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSP-DLR 554
           SLP+   CE +    C   L Y+ +++PN +      +A      F  L+ + CSP +L 
Sbjct: 612 SLPRS--CEALESAQCDMVLPYSASLYPNSMGHMTPTEAELASFEFLPLLAMGCSPVNLP 669

Query: 555 FFLCSVYAPVCTILDSAIPPWSSFM*SCKTK 647
            F+CS++ P C   D+ + P S    +  T+
Sbjct: 670 LFVCSLHFPSCG--DAPVLPCSELCRAAMTE 698


>UniRef50_Q4T9V1 Cluster: Chromosome undetermined SCAF7488, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF7488, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1022

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
 Frame = +3

Query: 375 GDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAAN--MLLFTTLIKLNCSPD 548
           GD  P   RCEPI ++ C+ L YN T  PN L    Q +++ +    LF  L++  C   
Sbjct: 332 GDGAPSAARCEPIGLELCRNLPYNSTSSPNFLGHQSQRESSVSWEASLFPALVQTGCYQY 391

Query: 549 LRFFLCSVYAPVC-TILDSAIPPWSSFM*SCKT 644
           L F+ C++  P C  +    +PP  S    C+T
Sbjct: 392 LMFYACTLLVPKCDPVTALRVPPCRSL---CRT 421



 Score = 39.9 bits (89), Expect = 0.052
 Identities = 19/62 (30%), Positives = 30/62 (48%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+PIT   C  L YNQT     ++  +  +    +  F+ L +L+C   +  F CS+  P
Sbjct: 2   CQPITEPQCHMLPYNQTWLSASVSVVKSSEVDMLLRFFSYLSRLSCYRHIMLFGCSLALP 61

Query: 582 VC 587
            C
Sbjct: 62  EC 63


>UniRef50_A7RPM4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 260

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 26/64 (40%), Positives = 34/64 (53%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+PIT+  CQ L YN T  PN L    Q      +  ++ LI  NCS DL F LC  + P
Sbjct: 5   CQPITVPACQSLPYNMTRLPNHLGHTSQRQIEHEINEYSQLISANCSADLVFLLCVYHLP 64

Query: 582 VCTI 593
           +C +
Sbjct: 65  ICAV 68


>UniRef50_UPI0000F2D00C Cluster: PREDICTED: hypothetical protein;
           n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
           protein - Monodelphis domestica
          Length = 317

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 33/86 (38%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
 Frame = +3

Query: 369 YQGDSLPQ---HGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLL-FTTLIKLN 536
           Y   SLPQ      CEPI ++ CQ L YN T FPN L     +     ML  + TL  L 
Sbjct: 123 YNCSSLPQLPFEPACEPIWVEMCQGLSYNSTAFPNTLMTLESQQEVEEMLKGYKTLTDLP 182

Query: 537 CSPDLRFFLCSVYAPVCTILDSAIPP 614
           C    R  LC +  P CT     +PP
Sbjct: 183 CYQPFRRLLCGLLLPHCTPSGGILPP 208


>UniRef50_UPI0000DB7495 Cluster: PREDICTED: similar to Corin
           CG2105-PA, isoform A; n=2; Apocrita|Rep: PREDICTED:
           similar to Corin CG2105-PA, isoform A - Apis mellifera
          Length = 1127

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
 Frame = +3

Query: 387 PQHGRCEPITIQFCQ--KLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFF 560
           P  G C PI + FC+  K+ YN TIFPN +    Q DA   + L++ +I + C      F
Sbjct: 558 PAPGVCLPIIVAFCKYHKIPYNFTIFPNYMGNFGQRDAQHELELYSAVIDVKCYELAALF 617

Query: 561 LCSVYAPVCTILDSAIPPWSS 623
           LCSV+ P C      + P  S
Sbjct: 618 LCSVFVPKCGSRGHVVRPCRS 638


>UniRef50_Q9BY79 Cluster: Membrane frizzled-related protein; n=15;
           Theria|Rep: Membrane frizzled-related protein - Homo
           sapiens (Human)
          Length = 579

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
 Frame = +3

Query: 387 PQHGRCEPITIQFCQKLRYNQTIFPNI-LNQARQEDAAANMLLFTTLIKLNCSPDLRFFL 563
           P    CEP+ ++ C  L YN T FPNI +    QE+    +  + +L  L C    R  L
Sbjct: 461 PPELACEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVEVLSGYKSLTSLPCYQHFRRLL 520

Query: 564 CSVYAPVCTILDSAIPPWSS 623
           C +  P CT L S +PP  S
Sbjct: 521 CGLLVPRCTPLGSVLPPCRS 540


>UniRef50_Q504J9 Cluster: Szl protein; n=6; Euteleostomi|Rep: Szl
           protein - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 39/105 (37%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
 Frame = +3

Query: 315 IFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQF--CQKLRYNQTIFPNILNQARQE 488
           +FSLL  F+L   +         L Q  RC PI  Q   CQ + Y++   PN+L     E
Sbjct: 10  LFSLLLFFSLAAHTGAF-----DLGQTTRCVPIPPQMSVCQDVPYSEMRLPNLLGHGSLE 64

Query: 489 DAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCTILDSAIPPWSS 623
           +AA       TL+   C P  R F+CS+ APVC  LD  I P  S
Sbjct: 65  EAAPRSDDLRTLLHTGCHPQARAFVCSLIAPVC--LDRFIQPCRS 107


>UniRef50_O77438 Cluster: Frizzled-3 precursor; n=3; Sophophora|Rep:
           Frizzled-3 precursor - Drosophila melanogaster (Fruit
           fly)
          Length = 581

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 26/68 (38%), Positives = 34/68 (50%)
 Frame = +3

Query: 387 PQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLC 566
           P   +C+PI +  CQ L YN T  PN+     Q +A   +     LI+  CS   RF LC
Sbjct: 35  PNGLQCQPIAVSACQGLGYNMTALPNLAGHTNQLEAELQIAKLVPLIESGCSRRARFLLC 94

Query: 567 SVYAPVCT 590
           S   P+CT
Sbjct: 95  SSLFPLCT 102


>UniRef50_UPI00004D1D0E Cluster: Membrane frizzled-related protein
           (Membrane-type frizzled-related protein).; n=1; Xenopus
           tropicalis|Rep: Membrane frizzled-related protein
           (Membrane-type frizzled-related protein). - Xenopus
           tropicalis
          Length = 435

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLL-FTTLIKLNCSPDLRFFLCSVYA 578
           C+P+ +  CQ L Y+QT FPN+     ++ AA+ +L  +  L +L C P LR F C++  
Sbjct: 322 CQPVQVPMCQGLSYSQTAFPNLWVSLHEQQAASELLTGYKILQELPCFPVLRPFFCALLV 381

Query: 579 PVCTILDSAIPPWSS 623
           P C+     + P  S
Sbjct: 382 PSCSAEGGVLQPCRS 396


>UniRef50_A7SXA8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 111

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           CE +  + C    YN TI PN LN   Q +A   M  F   I+ NCS  L+  +C+ Y P
Sbjct: 4   CERLKSKICLGFGYNDTILPNHLNHKSQGEAMRGMQRFLPFIRANCSTSLKALVCAAYFP 63

Query: 582 VCTILDS-AIPP 614
            CT   S A PP
Sbjct: 64  RCTKPQSYAAPP 75


>UniRef50_A1Z709 Cluster: CG2105-PB, isoform B; n=5; Diptera|Rep:
            CG2105-PB, isoform B - Drosophila melanogaster (Fruit
            fly)
          Length = 1397

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
 Frame = +3

Query: 387  PQHGRCEPITIQFCQ--KLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFF 560
            P  G C PI ++FCQ  ++ YN T+FPN +    Q +   ++  +  L+ + C   +  F
Sbjct: 774  PAPGTCLPIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLF 833

Query: 561  LCSVYAPVCTILDSAIPP 614
            LC+++ P C    + +PP
Sbjct: 834  LCTLFVPKCGQSGATVPP 851


>UniRef50_Q4H2U4 Cluster: Secreted frizzled-related protein; n=1;
           Ciona intestinalis|Rep: Secreted frizzled-related
           protein - Ciona intestinalis (Transparent sea squirt)
          Length = 293

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
 Frame = +3

Query: 357 RXIVYQGDSLPQHGRCEPITIQF--CQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIK 530
           R +++   + P   +CE I   F  C  + Y +   PN+L  A   +       +  L+ 
Sbjct: 34  RPLIFPQPAQPPDSKCEIIPEHFGLCYGMEYPRMRLPNLLGHATMTEVLQQSRFWPPLVS 93

Query: 531 LNCSPDLRFFLCSVYAPVCTI-LDSAIPP 614
             C+P+ R FLCS++APVC   +D +IPP
Sbjct: 94  KGCNPETRKFLCSLFAPVCMKGIDRSIPP 122


>UniRef50_A4UAH3 Cluster: Frizzled receptor 3; n=2; Eukaryota|Rep:
           Frizzled receptor 3 - Clytia hemisphaerica
          Length = 732

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
 Frame = +3

Query: 390 QHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLL-FTTLIKLNCSPDLRFFLC 566
           Q  RC P+    C+ L YN T+ PN+     + D AA  +  F+ L ++NC  + +FF+C
Sbjct: 24  QRERCVPLINDHCKDLGYNATLIPNVKAGIDKLDEAARRISEFSPLFQVNCYENFKFFIC 83

Query: 567 SVYAPVC 587
           +++ PVC
Sbjct: 84  NMFLPVC 90


>UniRef50_Q9GUF5 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 314

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P  +  C  + Y Q   PNIL      +A      + +L++LNC PD + FLCS++APVC
Sbjct: 41  PSNLSICNGIEYTQMRLPNILEHETVSEAIHASKDWESLLRLNCHPDTQRFLCSLFAPVC 100

Query: 588 TI-LDSAIPPWSS 623
            + +D  I P  S
Sbjct: 101 LMQMDRLILPCKS 113


>UniRef50_Q9W3H0 Cluster: CG1632-PA; n=5; Diptera|Rep: CG1632-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 1056

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 22/72 (30%), Positives = 39/72 (54%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           RC P+ + +C+++ YN T +PN+L  A  E  A ++++F  L+   C  +   F+C +  
Sbjct: 384 RCSPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQ 443

Query: 579 PVCTILDSAIPP 614
           P C    S + P
Sbjct: 444 PPCDTHGSDLQP 455


>UniRef50_Q5J0Z5 Cluster: LIN-17; n=1; Pristionchus pacificus|Rep:
           LIN-17 - Pristionchus pacificus
          Length = 563

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/93 (30%), Positives = 46/93 (49%)
 Frame = +3

Query: 309 VIIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQE 488
           +I   LL + ++T      +++  +    GRC P+  + C  + YN T  PN ++   Q 
Sbjct: 2   IIRLFLLFILSVTTTDAASIFEQST---KGRCVPMQHKMCADIPYNMTYHPNPISATEQS 58

Query: 489 DAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
                   F  LIK  C P ++FF+CSV+ P+C
Sbjct: 59  QIDH----FNPLIKTKCHPHIKFFVCSVFEPMC 87


>UniRef50_Q4RYT0 Cluster: Chromosome 16 SCAF14974, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
           SCAF14974, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 471

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNI-LNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           CE I ++ C+ L YN T FPNI L+ A Q +AAA +  +  L+ L C   LR  +C ++ 
Sbjct: 358 CETIEVEMCRGLSYNLTSFPNIWLSIADQREAAALLQQYRVLMDLACFQPLRRLVCGMFL 417

Query: 579 PVCTILDSAIPPWSS 623
           P C+     + P  S
Sbjct: 418 PQCSPQGGVLQPCRS 432


>UniRef50_Q4H3G0 Cluster: Frizzled receptor; n=2; Ciona|Rep:
           Frizzled receptor - Ciona intestinalis (Transparent sea
           squirt)
          Length = 810

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 10/87 (11%)
 Frame = +3

Query: 393 HGRCEPITIQFCQ----------KLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCS 542
           H +C P+T+  C           K  YN+T FPN  N A + +   ++ L   L+  +CS
Sbjct: 23  HPQCRPVTLPMCLRNNNERNKGIKWIYNETTFPNFNNDASESEVEISLSLLHPLLSTSCS 82

Query: 543 PDLRFFLCSVYAPVCTILDSAIPPWSS 623
             L  FLCSV++P C +    +PP  S
Sbjct: 83  RYLELFLCSVFSPAC-MGGGVVPPCRS 108


>UniRef50_Q96HF1 Cluster: Secreted frizzled-related protein 2
           precursor; n=24; Euteleostomi|Rep: Secreted
           frizzled-related protein 2 precursor - Homo sapiens
           (Human)
          Length = 295

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
 Frame = +3

Query: 372 QGDSLPQHGRCEPI--TIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSP 545
           Q D   +   C+PI   +Q C  + Y     PN+L     ++       +  L+   C P
Sbjct: 30  QPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHP 89

Query: 546 DLRFFLCSVYAPVC-TILDSAIPPWSS 623
           D + FLCS++APVC   LD  I P  S
Sbjct: 90  DTKKFLCSLFAPVCLDDLDETIQPCHS 116


>UniRef50_Q9NL45 Cluster: Frizzled homolog; n=2; Ciona
           intestinalis|Rep: Frizzled homolog - Ciona intestinalis
           (Transparent sea squirt)
          Length = 872

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = +3

Query: 396 GRCEPITIQFCQKLRYNQT---IFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLC 566
           G CEPI +  C  + YN T   + P+ +    Q++AA +++ F  L K  C+ +++  +C
Sbjct: 124 GVCEPIQVPMCIDIGYNFTDMSVSPSYIYD--QKEAAQSVIQFGPLTKTKCAEEMKLLVC 181

Query: 567 SVYAPVCTILDSAIPPWSSFM*SCK 641
           SVY P+C      IP +  F+  C+
Sbjct: 182 SVYTPIC------IPGYPGFLPPCR 200


>UniRef50_Q4H2U3 Cluster: Secreted frizzled-related protein; n=1;
           Ciona intestinalis|Rep: Secreted frizzled-related
           protein - Ciona intestinalis (Transparent sea squirt)
          Length = 152

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 27/96 (28%), Positives = 44/96 (45%)
 Frame = +3

Query: 324 LLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAAN 503
           + CL  L         Q  S  + G+C  +T   C+ +   +   P +L   ++  A   
Sbjct: 1   MFCLKLLFCSILIFSLQKYSFAKTGKCRKVTSGLCKDIISYKFSLPTLLKHTKRRSANKA 60

Query: 504 MLLFTTLIKLNCSPDLRFFLCSVYAPVCTILDSAIP 611
           + +F   IK+NCSP LR FLC+V+   C    + +P
Sbjct: 61  IRMFDPFIKMNCSPYLRPFLCTVFFAPCNRKGAKLP 96


>UniRef50_Q8JHC7 Cluster: Secreted frizzled-related protein; n=1;
           Danio rerio|Rep: Secreted frizzled-related protein -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 282

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 24/72 (33%), Positives = 35/72 (48%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P ++  C  + Y +   PN L   +  +       +  L+   CSPD R FLC ++AP+C
Sbjct: 32  PKSMALCYDIGYCEMRIPNHLEHEQMAEVLQQEWRWVPLLNKECSPDARIFLCCLFAPIC 91

Query: 588 TILDSAIPPWSS 623
             LDS I P  S
Sbjct: 92  WPLDSPIYPCRS 103


>UniRef50_Q4H2U5 Cluster: Secreted frizzled-related protein; n=1;
           Ciona intestinalis|Rep: Secreted frizzled-related
           protein - Ciona intestinalis (Transparent sea squirt)
          Length = 365

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 18/60 (30%), Positives = 34/60 (56%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P +++ C+ + Y + + PN+LN     +       F  L+  +C  +++ FLCS++APVC
Sbjct: 56  PTSLKLCRNVGYTRMVLPNLLNHESLTEVVQQATSFVPLLSRHCHANVQVFLCSLFAPVC 115


>UniRef50_Q4SF65 Cluster: Chromosome undetermined SCAF14608, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14608, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 650

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNIL-NQARQE-DAAANMLLFT---TLIKLNCSPDLRFFL 563
           RC  + + +C  + Y QT+FPN+  +++R+E +A A  LL +    L+   C+P++R   
Sbjct: 3   RCTDVLLSYCSDMSYTQTLFPNLAGHRSREETEAGAEYLLLSVAEALLGGRCNPEIRMLG 62

Query: 564 CSVYAPVCTILDSAIPPWSS 623
           CSV  P C   D+ + P  S
Sbjct: 63  CSVLVPRCQ-RDAVLRPCRS 81


>UniRef50_Q16VN8 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 990

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 18/63 (28%), Positives = 32/63 (50%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           +CEP+ + +C+ + YN T +PN       E+  A+++ F  L+   C      F+C +  
Sbjct: 335 KCEPLRLNYCRSVGYNMTTYPNFFGHGSIEEVEADLISFRELVDAECFRQAFDFVCRLLQ 394

Query: 579 PVC 587
           P C
Sbjct: 395 PPC 397


>UniRef50_A1IKD5 Cluster: Frizzled4/9/10; n=1; Hydra
           magnipapillata|Rep: Frizzled4/9/10 - Hydra
           magnipapillata (Hydra)
          Length = 567

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTI-----FPN-ILNQARQEDAAANMLLFTTLIKLNCSPDLRFF 560
           +C PI + FC+ + YN+TI       N   ++  Q++  + +  FT L++  CS  LR  
Sbjct: 41  KCVPIRLDFCKDVAYNETINMEGGISNPYTDKTNQDEIKSELSHFTLLLRTGCSVHLRLL 100

Query: 561 LCSVYAPVCT 590
           LCS Y P C+
Sbjct: 101 LCSAYLPYCS 110


>UniRef50_Q90ZA6 Cluster: Axszl; n=5; Euteleostomi|Rep: Axszl -
           Ambystoma mexicanum (Axolotl)
          Length = 284

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
 Frame = +3

Query: 399 RCEPITIQF--CQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSV 572
           +C P+  +   CQ + Y++   PN+L Q    +   +   +  L+   C P  R FLCS+
Sbjct: 28  KCVPVPREMGLCQDVGYSEMRLPNLLGQRSVAEVLPSSAQWLRLLHTGCHPHARTFLCSL 87

Query: 573 YAPVCTILDSAIPPWSS 623
           +AP+C  LD+ I P  S
Sbjct: 88  FAPIC--LDTFIQPCRS 102


>UniRef50_O42397 Cluster: Crescent; n=7; Euteleostomi|Rep: Crescent
           - Gallus gallus (Chicken)
          Length = 307

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 35/72 (48%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P ++  C  + Y++   PN+L      +       +  L+   C PD R FLCS++AP+C
Sbjct: 48  PRSMALCYDIGYSEMRIPNLLEHETMPEVIQQSSSWLPLLARECHPDARIFLCSLFAPIC 107

Query: 588 TILDSAIPPWSS 623
             LD  I P  S
Sbjct: 108 --LDRLIYPCRS 117


>UniRef50_UPI0000DB76D0 Cluster: PREDICTED: similar to CG1632-PA;
           n=2; Endopterygota|Rep: PREDICTED: similar to CG1632-PA
           - Apis mellifera
          Length = 777

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 20/67 (29%), Positives = 31/67 (46%)
 Frame = +3

Query: 387 PQHGRCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLC 566
           P   RC  + + +C+ L YN T +PNIL      D   +++ F  L+   C      F+C
Sbjct: 230 PPPRRCTSLNLSYCKHLPYNVTSYPNILGHRSLADVQEDVIAFRELVDAECYRLAYDFVC 289

Query: 567 SVYAPVC 587
            +  P C
Sbjct: 290 QILQPTC 296


>UniRef50_UPI00015B523C Cluster: PREDICTED: similar to conserved
           hypothetical protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to conserved hypothetical protein -
           Nasonia vitripennis
          Length = 779

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 19/63 (30%), Positives = 28/63 (44%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           RC PI   +C+ L YN T +PN        +   +++ F  L+   C      F+C V  
Sbjct: 235 RCSPIEFSYCKHLPYNVTSYPNFFGHNDAREVNDDIIAFRELVDAECYKQAYDFICQVLQ 294

Query: 579 PVC 587
           P C
Sbjct: 295 PAC 297


>UniRef50_Q0IHH5 Cluster: Putative uncharacterized protein; n=1;
           Xenopus laevis|Rep: Putative uncharacterized protein -
           Xenopus laevis (African clawed frog)
          Length = 288

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P T+  C  + Y +   PN+L     ++A      +  L+   C  D + FLCS++APVC
Sbjct: 38  PGTMTLCHGVGYTEMRLPNLLGHDTMKEALQQAGSWVPLLSKQCHADTKKFLCSLFAPVC 97

Query: 588 -TILDSAIPPWSS 623
            + LD A+ P  S
Sbjct: 98  LSELDQAVYPCRS 110


>UniRef50_UPI0000E20752 Cluster: PREDICTED: hypothetical protein;
           n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
           protein - Pan troglodytes
          Length = 1006

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQE--DAAANMLLFTTLIKL---NCSPDLRFFLC 566
           C  + ++ C    YN T FPN+L     E  +A++  +L + L +L    C+PDLR   C
Sbjct: 344 CMDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGC 403

Query: 567 SVYAPVC 587
           +V AP C
Sbjct: 404 AVLAPRC 410


>UniRef50_Q66K79 Cluster: Carboxypeptidase Z precursor; n=26;
           Euteleostomi|Rep: Carboxypeptidase Z precursor - Homo
           sapiens (Human)
          Length = 652

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQE--DAAANMLLFTTLIKL---NCSPDLRFFLC 566
           C  + ++ C    YN T FPN+L     E  +A++  +L + L +L    C+PDLR   C
Sbjct: 43  CVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGC 102

Query: 567 SVYAPVC 587
           +V AP C
Sbjct: 103 AVLAPRC 109


>UniRef50_A7RPS6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 282

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
 Frame = +3

Query: 441 YNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVCT-ILDSAIPPW 617
           YN+ + PN L      +    ++ +  L+   CSP L+ FLCSV+ PVC   +   +PP 
Sbjct: 46  YNKIMLPNALGHDNLAEVRTQLVPWAPLVGSGCSPHLKVFLCSVFMPVCVQQISYPVPPC 105

Query: 618 SS 623
            S
Sbjct: 106 HS 107


>UniRef50_Q8JFF5 Cluster: Type XVIII collagen long variant; n=2;
           Xenopus laevis|Rep: Type XVIII collagen long variant -
           Xenopus laevis (African clawed frog)
          Length = 634

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
 Frame = +3

Query: 387 PQHGRC--EPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFF 560
           P + RC   P ++ FC++L  +  + PN LN +   +  A +  +  L K  C   L +F
Sbjct: 491 PPNARCFPTPTSLSFCKRLGIDSFLLPNFLNHSTVLEIQAALHDWEGLFKSQCHQYLEWF 550

Query: 561 LCSVYAPVCTILDSAIPP 614
            C + AP C     A PP
Sbjct: 551 FCLLLAPSCNTGTLAPPP 568


>UniRef50_UPI0000E48FF8 Cluster: PREDICTED: similar to fibropellin
           Ib, partial; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to fibropellin Ib, partial -
           Strongylocentrotus purpuratus
          Length = 1037

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 27/64 (42%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +3

Query: 402 CEPITIQFC-QKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           CE +    C Q L YN T FPN  N    + AA N     T I  +C   L  F+CSVY 
Sbjct: 159 CEQVQFDICRQSLAYNLTFFPN-RNAETADAAAGNFTDMGTTIS-SCHDHLFPFMCSVYY 216

Query: 579 PVCT 590
           P CT
Sbjct: 217 PECT 220


>UniRef50_Q4H2U2 Cluster: Secreted frizzled-related protein; n=1;
           Ciona intestinalis|Rep: Secreted frizzled-related
           protein - Ciona intestinalis (Transparent sea squirt)
          Length = 148

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 20/64 (31%), Positives = 32/64 (50%)
 Frame = +3

Query: 399 RCEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           +C+ +T   C  +     + PN+     Q++A   +  +  LI + CSP L+ FLCS Y 
Sbjct: 25  KCKQVTTPMCSDIIRYPVLMPNMFGHRSQDEANHVIQQYKPLISVACSPFLKPFLCSAYF 84

Query: 579 PVCT 590
             CT
Sbjct: 85  SPCT 88


>UniRef50_Q5VKN1 Cluster: Frizzled-8; n=2; Elopocephala|Rep:
           Frizzled-8 - Elops hawaiensis (Hawaiian ladyfish)
          Length = 294

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 18/46 (39%), Positives = 29/46 (63%)
 Frame = +3

Query: 450 TIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           TI+  +  + R+ D     +    L+++ CSPDL+FFLCS+Y P+C
Sbjct: 3   TIY-TVTGRDRKTDTEKAHMSTWPLVEIQCSPDLKFFLCSMYTPIC 47


>UniRef50_UPI0000588F3D Cluster: PREDICTED: similar to secreted
           frizzled-related protein 1; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to secreted
           frizzled-related protein 1 - Strongylocentrotus
           purpuratus
          Length = 422

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 20/72 (27%), Positives = 33/72 (45%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P  +  CQ + Y +   PN+L     ++       +  L+   C    + FLC+++APVC
Sbjct: 55  PEDLSLCQNIGYTRMRMPNLLEHDSLDEVRNQAKSWVPLLLQRCHEGTQLFLCTLFAPVC 114

Query: 588 TILDSAIPPWSS 623
             +D  I P  S
Sbjct: 115 LEVDRPIYPCRS 126


>UniRef50_UPI00005A0542 Cluster: PREDICTED: similar to
           carboxypeptidase Z isoform 2 precursor; n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to carboxypeptidase Z
           isoform 2 precursor - Canis familiaris
          Length = 701

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 5/62 (8%)
 Frame = +3

Query: 417 IQFCQKLRYNQTIFPNILNQARQE--DAAANMLLFTTLIKL---NCSPDLRFFLCSVYAP 581
           ++ C  + YN T FP +L Q  +E  ++++  +L + L  L    C+PDLR   C+V AP
Sbjct: 3   LRTCSDVAYNWTTFPTLLEQRSREAVESSSEYILLSVLHHLLEGQCNPDLRLLGCAVLAP 62

Query: 582 VC 587
            C
Sbjct: 63  RC 64


>UniRef50_UPI0000E47712 Cluster: PREDICTED: similar to echinonectin,
            partial; n=14; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to echinonectin, partial -
            Strongylocentrotus purpuratus
          Length = 1967

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
 Frame = +3

Query: 402  CEPITIQFC-QKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
            CE +    C Q L Y+ T FPN    A   DAAA           +C   L  F+CSVY 
Sbjct: 1785 CEQVQFDICRQNLAYSVTFFPN--GNAETADAAAESFTEIADTISSCHDHLFPFMCSVYY 1842

Query: 579  PVCT 590
            P CT
Sbjct: 1843 PECT 1846



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
 Frame = +3

Query: 402 CEPITIQFC-QKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           CE +    C Q L Y+ T FPN    A   DAAA           +C   L  F+CSVY 
Sbjct: 594 CEQVQFDKCRQNLAYSVTFFPN--GNAETADAAAESFTEIEATISSCHDHLIPFMCSVYY 651

Query: 579 PVCT 590
           P CT
Sbjct: 652 PECT 655


>UniRef50_UPI0000D9C447 Cluster: PREDICTED: similar to secreted
           frizzled-related protein 5; n=2; Catarrhini|Rep:
           PREDICTED: similar to secreted frizzled-related protein
           5 - Macaca mulatta
          Length = 376

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 22/72 (30%), Positives = 32/72 (44%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P  +  C  + Y +   PN+L      +       +  L+   C  D + FLCS++APVC
Sbjct: 116 PADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC 175

Query: 588 TILDSAIPPWSS 623
             LD  I P  S
Sbjct: 176 --LDRPIYPCRS 185


>UniRef50_Q5T4F7 Cluster: Secreted frizzled-related protein 5
           precursor; n=60; Euteleostomi|Rep: Secreted
           frizzled-related protein 5 precursor - Homo sapiens
           (Human)
          Length = 317

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 22/72 (30%), Positives = 32/72 (44%)
 Frame = +3

Query: 408 PITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAPVC 587
           P  +  C  + Y +   PN+L      +       +  L+   C  D + FLCS++APVC
Sbjct: 57  PADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC 116

Query: 588 TILDSAIPPWSS 623
             LD  I P  S
Sbjct: 117 --LDRPIYPCRS 126


>UniRef50_A7SA89 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1276

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = +3

Query: 387 PQHGRCEPITIQFCQKLRYNQTI-FPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFL 563
           P    C+P+TI+ C K  Y  T  +P++  Q  Q+  A  +  +  L+K  CS      L
Sbjct: 308 PVSKHCQPMTIKSCAKAGYPFTFSYPDVNGQPYQQAKALYLDYYLNLLK--CSKLSELVL 365

Query: 564 CSVYAPVC 587
           CS+Y P C
Sbjct: 366 CSMYVPQC 373


>UniRef50_UPI0000F33F4D Cluster: UPI0000F33F4D related cluster; n=1;
           Bos taurus|Rep: UPI0000F33F4D UniRef100 entry - Bos
           Taurus
          Length = 486

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
 Frame = +3

Query: 396 GRCEPI--TIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCS 569
           GRC P+  ++  C  L   ++ +PN L+   +E+  A +  +  L++ +C   L +F C 
Sbjct: 349 GRCLPLLPSLALCGHLGIRRSWWPNHLHHTSREEVQAAVPAWGALLRTHCHRFLAWFFCL 408

Query: 570 VYAPVC-TILDSAIPPWSSF 626
           + AP C   L   +PP   F
Sbjct: 409 LLAPPCGPGLPPGLPPCRQF 428


>UniRef50_Q2PBM7 Cluster: Long form of collagen XVIII alpha 1 chain;
           n=7; Danio rerio|Rep: Long form of collagen XVIII alpha
           1 chain - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1396

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
 Frame = +3

Query: 339 ALTKGSRXIVYQGDSLPQHGRCEPIT--IQFCQKLRYNQTIFPNILNQARQEDAAANMLL 512
           ALT  S+ ++    +  +  RC P+   + FC +        PN LNQ+  E+    +  
Sbjct: 186 ALTIESQFLIASMPASFEPLRCLPVDSGLPFCTRRGVESFSVPNFLNQSSVEEVRMVLTE 245

Query: 513 FTTLIKLNCSPDLRFFLCSVYAPVCTILDSAIPPWSS 623
           +  L++  C   L +F C +  P C    S +P  SS
Sbjct: 246 WAWLLRSGCHHSLEWFFCLLLTPRCGHSGSLLPCRSS 282


>UniRef50_UPI0000E48747 Cluster: PREDICTED: similar to protease,
           serine, 7 (enterokinase), partial; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           protease, serine, 7 (enterokinase), partial -
           Strongylocentrotus purpuratus
          Length = 558

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
 Frame = +3

Query: 399 RCEPITIQFCQKLR-YNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVY 575
           RCEPI    C  L  YNQT +P+ L    Q  A  +  + +      C  D   FLC+V 
Sbjct: 267 RCEPIKESSCLGLLPYNQTYYPSSLADINQTLAIESFSVLSAAAT-TCHTDASLFLCAVL 325

Query: 576 APVC 587
            P C
Sbjct: 326 FPEC 329


>UniRef50_P39060 Cluster: Collagen alpha-1(XVIII) chain precursor
           [Contains: Endostatin]; n=28; Tetrapoda|Rep: Collagen
           alpha-1(XVIII) chain precursor [Contains: Endostatin] -
           Homo sapiens (Human)
          Length = 1754

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
 Frame = +3

Query: 396 GRCEPI--TIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCS 569
           GRC P+  ++  C  L  ++   PN L+    E   A    +  L++ +C P L +F C 
Sbjct: 332 GRCLPLPPSLPVCGHLGISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCL 391

Query: 570 VYAPVCTILDSAIPP 614
           +  P C  +    PP
Sbjct: 392 LLVPPCGSVPPPAPP 406


>UniRef50_Q5YGP6 Cluster: Blue pigment protein precursor; n=1;
           Rhizostoma pulmo|Rep: Blue pigment protein precursor -
           Rhizostoma pulmo (Jellyfish)
          Length = 264

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
 Frame = +3

Query: 408 PITIQFCQ-KLRYNQTIFPNILNQARQEDAAANMLL--FTTLIKLNCSPDLRFFLCSVYA 578
           P+ I+FC+  + Y++T   N + Q  Q     + L     TL K  CS     + C+ YA
Sbjct: 37  PLNIEFCRLAMGYSETAKINFMQQTNQSLVQQDRLFKALLTLSKFGCSELTEAYTCATYA 96

Query: 579 PVCTILDSAIPPWSS 623
           P       A+PP  S
Sbjct: 97  PPVIAPYGALPPCRS 111


>UniRef50_Q4RMT0 Cluster: Chromosome 3 SCAF15018, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 3 SCAF15018, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 379

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 402 CEPITIQF--CQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVY 575
           C P+   +  C          PN+LN    ++  A +  +  L++  C P   +FLC + 
Sbjct: 105 CLPVPSDWPICSSKHPRSLTLPNLLNHTSVDEVGAVLAEWAWLVEKGCHPSAEWFLCLLL 164

Query: 576 APVCTILDSAIPPWSSF 626
            P C     A PP  SF
Sbjct: 165 VPGCP--GRAPPPCRSF 179


>UniRef50_Q70LH3 Cluster: Frizzled receptor; n=1; Suberites
           domuncula|Rep: Frizzled receptor - Suberites domuncula
           (Sponge)
          Length = 529

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
 Frame = +3

Query: 312 IIFSLLCLFALTKGSRXIVYQGDSLPQHGRCEPITIQFCQKLRYNQTIFPNILNQARQED 491
           +++ +L L A    S+  +    S    G C P     C  L Y+ T +PN +       
Sbjct: 3   LVWFILVLLASGSHSQQPLCDNQSPTAFGSCVPAPTA-CDML-YSSTAYPNNVTTTSMM- 59

Query: 492 AAANMLLFTTLIK-LNCSPDLRFFLCSVYAPVCT 590
           + + ++ +   +  ++CSP  + F+C   APVCT
Sbjct: 60  SVSRLIAYQPFVNVIDCSPYSQLFICLSLAPVCT 93


>UniRef50_UPI0000E48793 Cluster: PREDICTED: similar to egg bindin
            receptor 1 precursor; n=2; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to egg bindin receptor
            1 precursor - Strongylocentrotus purpuratus
          Length = 1470

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
 Frame = +3

Query: 399  RCEPITIQFCQKLR-YNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVY 575
            RCEPI    C  L  +NQT +P+ L    Q  A  +  + +      C  D   FLC+V 
Sbjct: 1090 RCEPIQEGSCLGLLPFNQTYYPSSLADINQTLAIESFSVLSAAAT-TCHTDASLFLCAVL 1148

Query: 576  APVC 587
             P C
Sbjct: 1149 FPEC 1152


>UniRef50_UPI0001554ED1 Cluster: PREDICTED: similar to type XVIII
           collagen long, partial; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to type XVIII collagen
           long, partial - Ornithorhynchus anatinus
          Length = 512

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 2/78 (2%)
 Frame = +3

Query: 387 PQHGRCEPITIQF--CQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFF 560
           P  G C P+   +  C++L   +   PN LN +        +  +  L++  C   L +F
Sbjct: 390 PSAGHCWPVPADWSICRRLGIERFWLPNYLNHSSDLQIREALHEWEGLLRSQCHRLLEWF 449

Query: 561 LCSVYAPVCTILDSAIPP 614
            C V  P C      +PP
Sbjct: 450 FCLVLVPQCNASLPIMPP 467


>UniRef50_A7S829 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 529

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
 Frame = +3

Query: 399 RCEPITIQFC--QKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKL-NCSPDLRFFLCS 569
           +CEP+  Q C  +KL Y+ T    + + + Q+    N+  +  L  L  C   L+ FLC 
Sbjct: 25  KCEPLKEQTCLGEKLDYHYTTTELVTDSSSQDQVKKNLEKWEGLKFLPKCWEVLQPFLCQ 84

Query: 570 VYAPVC 587
           +Y P C
Sbjct: 85  IYKPKC 90


>UniRef50_UPI0000E48E51 Cluster: PREDICTED: similar to human
           enterokinase; EC 3.4.21.9.; n=7; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to human
           enterokinase; EC 3.4.21.9. - Strongylocentrotus
           purpuratus
          Length = 1043

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 17/62 (27%), Positives = 28/62 (45%)
 Frame = +3

Query: 402 CEPITIQFCQKLRYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYAP 581
           C+P+  +    L +  T+FPN   Q+  +       L +T   L+C P  +  LC+   P
Sbjct: 678 CQPVPSECSSVLPWTTTVFPNARYQSESDALQRYAELEST--ALSCDPSGQLLLCAALFP 735

Query: 582 VC 587
            C
Sbjct: 736 EC 737


>UniRef50_Q5E034 Cluster: Superfamily I DNA helicases and helicase
           subunits; n=1; Vibrio fischeri ES114|Rep: Superfamily I
           DNA helicases and helicase subunits - Vibrio fischeri
           (strain ATCC 700601 / ES114)
          Length = 1354

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 14/29 (48%), Positives = 19/29 (65%)
 Frame = +3

Query: 372 QGDSLPQHGRCEPITIQFCQKLRYNQTIF 458
           QG SL  H RC+ +  QFC +L Y+ +IF
Sbjct: 777 QGMSLRGHYRCQEVLSQFCNELVYDNSIF 805


>UniRef50_UPI0000E45FA6 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 1159

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
 Frame = +3

Query: 402 CEPITIQFCQKL-RYNQTIFPNILNQARQEDAAANMLLFTTLIKLNCSPDLRFFLCSVYA 578
           C  +    C++L  YN+T FPN    A+  D+A +++  T++++  C  D     CS+  
Sbjct: 787 CTDLRFSTCEELLSYNRTYFPN--PTAQDRDSAISLIEETSILE-ECHEDFLLLFCSMLF 843

Query: 579 PVC 587
             C
Sbjct: 844 ADC 846


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 563,538,426
Number of Sequences: 1657284
Number of extensions: 9990493
Number of successful extensions: 17946
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 17375
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17924
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48955894634
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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