Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_P18
(1180 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4; ... 361 2e-98
UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA... 281 2e-74
UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocystei... 277 4e-73
UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-... 258 2e-67
UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine... 230 5e-59
UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella ve... 219 2e-55
UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome sh... 216 1e-54
UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1; ... 177 6e-43
UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG... 176 8e-43
UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=3... 173 7e-42
UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;... 166 1e-39
UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;... 165 1e-39
UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;... 149 2e-34
UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1; Ja... 146 1e-33
UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 145 2e-33
UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase, putat... 144 3e-33
UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1; ... 125 3e-31
UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2; ... 134 6e-30
UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2; ... 132 2e-29
UniRef50_UPI000050FD2A Cluster: COG2040: Homocysteine/selenocyst... 129 1e-28
UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4; ... 128 3e-28
UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 127 6e-28
UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1; ... 126 8e-28
UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1; Pl... 117 7e-25
UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransfera... 116 2e-24
UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to 5-methylte... 110 8e-23
UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1; ... 108 2e-22
UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of s... 105 3e-21
UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1; ... 95 4e-18
UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase; ... 89 2e-16
UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of str... 84 8e-15
UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1; ... 83 2e-14
UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;... 81 5e-14
UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1; ... 80 1e-13
UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2; ... 75 4e-12
UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;... 75 4e-12
UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase, putat... 74 6e-12
UniRef50_Q2TXK9 Cluster: Predicted protein; n=2; Trichocomaceae|... 73 1e-11
UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1; ... 71 6e-11
UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein NCU007... 70 1e-10
UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1; ... 67 1e-09
UniRef50_Q966F6 Cluster: Putative uncharacterized protein T13G4.... 65 3e-09
UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Re... 64 5e-09
UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1; ... 64 9e-09
UniRef50_Q4WFR2 Cluster: Homocysteine S-methyltransferase, putat... 61 6e-08
UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase, putat... 57 8e-07
UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=... 57 1e-06
UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9... 55 3e-06
UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25; Cyanobacteri... 55 4e-06
UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Re... 54 5e-06
UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family... 54 5e-06
UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2; ... 54 5e-06
UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine m... 53 1e-05
UniRef50_A4XIN5 Cluster: Methylenetetrahydrofolate reductase; n=... 53 2e-05
UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5; ... 51 7e-05
UniRef50_P74718 Cluster: Slr1189 protein; n=1; Synechocystis sp.... 50 1e-04
UniRef50_Q93A68 Cluster: Methylenetetrahydrofolate reductase; n=... 50 1e-04
UniRef50_A5UPF4 Cluster: Methionine synthase; n=4; Chloroflexace... 50 1e-04
UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family... 50 1e-04
UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase, putat... 50 1e-04
UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1; ... 49 3e-04
UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1; ... 49 3e-04
UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine syntha... 48 4e-04
UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1; ... 48 4e-04
UniRef50_Q2LQ11 Cluster: Methylenetetrahydrofolate reductase; n=... 48 5e-04
UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium... 48 6e-04
UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine ... 47 0.001
UniRef50_A1GFF8 Cluster: Homocysteine S-methyltransferase; n=2; ... 46 0.001
UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associa... 45 0.004
UniRef50_Q748M7 Cluster: Methylenetetrahydrofolate reductase; n=... 45 0.004
UniRef50_Q1IQK2 Cluster: 5-methyltetrahydrofolate--homocysteine ... 44 0.006
UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransfera... 44 0.006
UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase, putat... 44 0.010
UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:... 43 0.013
UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1; ... 43 0.013
UniRef50_Q55786 Cluster: Methionine synthase; n=5; Cyanobacteria... 43 0.013
UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine... 43 0.018
UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella suc... 43 0.018
UniRef50_Q024B4 Cluster: Homocysteine S-methyltransferase; n=1; ... 43 0.018
UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 43 0.018
UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:... 42 0.023
UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=... 42 0.031
UniRef50_Q6AL45 Cluster: Related to 5-methyltetrahydrofolate--ho... 42 0.031
UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family... 42 0.031
UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=... 42 0.031
UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 42 0.031
UniRef50_Q8DCJ7 Cluster: Methionine synthase; n=51; Bacteria|Rep... 42 0.031
UniRef50_Q99707 Cluster: Methionine synthase; n=268; cellular or... 42 0.031
UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;... 42 0.041
UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2; ... 41 0.054
UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1; ... 41 0.054
UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;... 40 0.095
UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=... 40 0.095
UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransfera... 40 0.095
UniRef50_A7RIN6 Cluster: Predicted protein; n=2; Nematostella ve... 40 0.095
UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3; ... 40 0.12
UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine syntha... 40 0.12
UniRef50_Q161X1 Cluster: Homocysteine S-methyltransferase, putat... 40 0.12
UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine ... 40 0.12
UniRef50_Q8R927 Cluster: Methionine synthase I, cobalamin-bindin... 39 0.22
UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep... 39 0.22
UniRef50_Q9I2Q2 Cluster: Methionine synthase; n=95; Bacteria|Rep... 39 0.22
UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=... 39 0.29
UniRef50_Q2AGF5 Cluster: Dihydropteroate synthase, DHPS:Homocyst... 38 0.38
UniRef50_Q1NSQ8 Cluster: Methylenetetrahydrofolate reductase; n=... 38 0.50
UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 38 0.50
UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine ... 38 0.67
UniRef50_A0RW49 Cluster: Methionine synthase I (Cobalamin-depend... 38 0.67
UniRef50_Q1WUH1 Cluster: TRNA delta(2)-isopentenylpyrophosphate ... 37 0.88
UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4; ... 37 0.88
UniRef50_A7DNT5 Cluster: Homocysteine S-methyltransferase; n=1; ... 37 0.88
UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2; ... 36 2.0
UniRef50_Q8ESE8 Cluster: Betaine-homocysteine methyltransferase;... 36 2.7
UniRef50_A5ZSP9 Cluster: Putative uncharacterized protein; n=1; ... 35 3.6
UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4; ... 35 3.6
UniRef50_Q1GGL5 Cluster: Homocysteine S-methyltransferase; n=30;... 35 4.7
UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2; ... 35 4.7
UniRef50_A7CWS4 Cluster: Homocysteine S-methyltransferase precur... 34 6.2
UniRef50_Q74DI9 Cluster: Homocysteine S-methyltransferase domain... 34 8.2
UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine... 34 8.2
UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep... 34 8.2
UniRef50_A5ZUF2 Cluster: Putative uncharacterized protein; n=1; ... 34 8.2
UniRef50_A5Z6N8 Cluster: Putative uncharacterized protein; n=1; ... 34 8.2
UniRef50_Q4YA86 Cluster: Putative uncharacterized protein; n=1; ... 34 8.2
>UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4;
Endopterygota|Rep: Homocysteine S-methyltransferase -
Bombyx mori (Silk moth)
Length = 325
Score = 361 bits (888), Expect = 2e-98
Identities = 162/270 (60%), Positives = 207/270 (76%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+ VLDGGFSTQL+CH GH DGDPL SARF+ THP +V+NTHLDFLRAG+D+I TNTYQA
Sbjct: 11 VFVLDGGFSTQLTCHAGHTADGDPLGSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 70
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
SV+G V+HL +T E+ YELI AV+ A+ AR LYL+E ++ + PLI GSVGPYGA+
Sbjct: 71 SVDGLVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAY 130
Query: 596 LHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF 775
LHD SEY G+YAD T+ ET++ WHR RIQALVEAGVD+LA ETIPCQ+EAE L ++L+E+
Sbjct: 131 LHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEY 190
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMKGXND 955
P KAWL+FSCK++ S+AHGE+FQ VAKKCW+ NPDQL+A+GVN C+ V+ L K N+
Sbjct: 191 PNMKAWLSFSCKNETSLAHGENFQNVAKKCWKSNPDQLIAIGVNGCSPKIVTELFKDINN 250
Query: 956 DRPQAPXRLWLP*FGRKYNPQIGXINRDKC 1045
D+ + + P G Y+ ++G DKC
Sbjct: 251 DQETSIQYITYPNSGETYDHKLGWTESDKC 280
>UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG10621-PA
- Apis mellifera
Length = 320
Score = 281 bits (690), Expect = 2e-74
Identities = 134/279 (48%), Positives = 188/279 (67%), Gaps = 6/279 (2%)
Frame = +2
Query: 233 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 412
++ +LDGGF QLS HV +DGDPLW+++F+ T+PN V THLDFL+AGAD+I TNTYQ
Sbjct: 2 NVKILDGGFGAQLSTHVNEKVDGDPLWTSKFLVTNPNAVYATHLDFLKAGADIIETNTYQ 61
Query: 413 ASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI----PLIVGSVG 580
AS+ ++HL ++KE+ +L+ +AV LAK A Y +E + N+D+ P+IV S G
Sbjct: 62 ASIPSLMKHLSISKEESIKLLHKAVHLAKTAVNDYTKEV---INNNDVENKNPMIVASCG 118
Query: 581 PYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCD 760
PYGA LHDGSEY+G+Y T E + +WH+ RI A++ AG+DLLALETIPC +EAE + +
Sbjct: 119 PYGASLHDGSEYNGAYGKITPRENIIQWHKSRIDAIINAGIDLLALETIPCYQEAEAIIE 178
Query: 761 LLREFPGTKAWLAFSC-KDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNL 937
+LRE+P TKAWL+FSC K+ Q I G +FQ+++ +C++ P Q+VA+GVNC A V+ L
Sbjct: 179 VLREYPNTKAWLSFSCEKNTQKIVDGSNFQELSTRCYKTLPGQIVAIGVNCIAPKDVTPL 238
Query: 938 MKGXN-DDRPQAPXRLWLP*FGRKYNPQIGXINRDKCXP 1051
+K N + P G Y+P G I + C P
Sbjct: 239 LKNINMGSGNDFIPLIAYPNSGEIYSPNEGWIKNESCAP 277
>UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocysteine
S-methyltransferase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to homocysteine S-methyltransferase -
Nasonia vitripennis
Length = 341
Score = 277 bits (679), Expect = 4e-73
Identities = 133/261 (50%), Positives = 187/261 (71%), Gaps = 3/261 (1%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
+++DGGFSTQL HVG VIDGDPLW++RF++++P+ V THLD+LRAG+ +I T TYQAS
Sbjct: 24 IIIDGGFSTQLVTHVGEVIDGDPLWTSRFLYSNPDAVFQTHLDYLRAGSHVIETATYQAS 83
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
+ G+V++L T+E+ +LI AV+LAK+A +Y EE + ++ P++ GS+GPY A+L
Sbjct: 84 IPGYVKYLDRTEEEALQLIKTAVELAKKAVRVYKEEIKGKDVSNPEPMVAGSIGPYAAYL 143
Query: 599 HDGSEY-DGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF 775
HD SEY GSYA+ S++++ EWHRPR +AL+ GVDLLA+ETIPC EAE L LL+++
Sbjct: 144 HDCSEYTGGSYANIESMDSIVEWHRPRFEALINGGVDLLAIETIPCAREAEALVGLLKQY 203
Query: 776 PGTKAWLAFSCK-DDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMKGXN 952
P TKAWL+FSCK D +SIA G SF++ KC++ Q+VA GVNC A V+ L+K N
Sbjct: 204 PDTKAWLSFSCKVDGKSIADGSSFKQTVLKCYKAASGQIVACGVNCLAPRSVTPLLKSIN 263
Query: 953 D-DRPQAPXRLWLP*FGRKYN 1012
+ + Q + P G KY+
Sbjct: 264 EKEINQFIPMVAYPNSGEKYS 284
>UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-PA
- Drosophila melanogaster (Fruit fly)
Length = 331
Score = 258 bits (633), Expect = 2e-67
Identities = 126/247 (51%), Positives = 173/247 (70%), Gaps = 6/247 (2%)
Frame = +2
Query: 218 NTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLII 397
N + I+V GGFS+QL+ +V +DGDPLW +RF T+P V+ THLDFLR GAD+I+
Sbjct: 8 NWDTKPILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIIL 67
Query: 398 TNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSV 577
TNTYQ+SVEGFV++LGVT+E+G ELI ++VQLAKQA+ YL E ++ +PLI+GS+
Sbjct: 68 TNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAES-ALPLIMGSI 126
Query: 578 GPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLC 757
GPYGA+LHDGSEY G+YAD S E +R WH+ RI+ + AGVD LALET+PC EAE +
Sbjct: 127 GPYGAYLHDGSEYTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVT 186
Query: 758 DL-LREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWEL-----NPDQLVAVGVNCCAR 919
+L L FP K W++ C D++ +A GE+F + A W L ++L+ +G+NC
Sbjct: 187 ELVLDNFPDAKFWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNP 246
Query: 920 SFVSNLM 940
FV+ L+
Sbjct: 247 LFVTPLL 253
>UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine
S-methyltransferase domain; n=7; Euteleostomi|Rep: Novel
protein containing a homocysteine S-methyltransferase
domain - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 318
Score = 230 bits (563), Expect = 5e-59
Identities = 112/238 (47%), Positives = 160/238 (67%), Gaps = 4/238 (1%)
Frame = +2
Query: 242 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 421
+LDGG +T+L G + GDPLWSAR +HT P + + H +L++G+D+I T TYQAS+
Sbjct: 14 ILDGGLATELEAS-GFQLQGDPLWSARVLHTDPQAIKDVHYRYLQSGSDVITTATYQASI 72
Query: 422 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLH 601
EGFV++LGV E+ ++ AVQLAK+ + ++ + + + PL+ GSVGPYG+ LH
Sbjct: 73 EGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFISQ--SPMSDRREPLVAGSVGPYGSFLH 130
Query: 602 DGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFPG 781
DGSEY G+Y D ++E +++WHRP+IQ LV+AG DL+A+ETIP +EAE L +L+EFP
Sbjct: 131 DGSEYTGAYEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIPGLKEAEALVKVLKEFPE 190
Query: 782 TKAWLAFSC----KDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMK 943
TKAWL+FS +D+ SI+ G F + + QLVAVGVNCC V L++
Sbjct: 191 TKAWLSFSSINLFQDNNSISSGRRFSEAVEMA--CRSTQLVAVGVNCCPALLVKPLLE 246
>UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 265
Score = 219 bits (534), Expect = 2e-55
Identities = 105/217 (48%), Positives = 145/217 (66%)
Frame = +2
Query: 293 IDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYEL 472
+ GDPLWSAR + +P V H FL G+D+I T TYQAS+ GF +HLGVT ++ +L
Sbjct: 3 MQGDPLWSARVLVENPEAVKQVHKSFLTHGSDIITTATYQASISGFCKHLGVTADEARKL 62
Query: 473 IARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIET 652
I R V +A+++ ++E+ D N P + GSV PYG DGSEY G+Y DT +I+
Sbjct: 63 IQRGVHIARES----VDEFWDKHSNS--PQVAGSVCPYGTCQSDGSEYHGNYVDTMTIKN 116
Query: 653 MREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAH 832
+ +WHRP+IQALVE G+DLLA ETIP Q+E E L LL+EFPGTKAWL++SCKD +H
Sbjct: 117 LMDWHRPQIQALVETGLDLLAFETIPAQKEGEALVQLLKEFPGTKAWLSYSCKDGSHTSH 176
Query: 833 GESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMK 943
E F A + +Q++AVG NCC+ +V++L++
Sbjct: 177 NEDFVS-AIMAAVADSEQIIAVGNNCCSPVYVTSLIR 212
>UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome shotgun
sequence; n=4; Euteleostomi|Rep: Chromosome 1 SCAF14770,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 372
Score = 216 bits (527), Expect = 1e-54
Identities = 120/303 (39%), Positives = 169/303 (55%), Gaps = 24/303 (7%)
Frame = +2
Query: 242 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 421
+LDGG +T L H + GDPLWSAR ++T+P + + H FL +GAD+I T TYQASV
Sbjct: 18 ILDGGLATDLEAQGVH-LQGDPLWSARLLYTNPQAIRDAHCRFLLSGADVISTATYQASV 76
Query: 422 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLE--EYRDYVQNDD-------------- 553
EGF++HL V+ E ELI VQLAK+A ++ VQ+ +
Sbjct: 77 EGFMDHLNVSSEGAKELIMSGVQLAKEAVESFVPGTNPNTTVQSGEGKVNSEGSEGLAGQ 136
Query: 554 ------IPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLA 715
PL+ GS+GPYGA LH+GSEY G YA+ S++ ++ WHRP+++ L A D+LA
Sbjct: 137 CSSGRRCPLVAGSLGPYGAFLHNGSEYTGDYAEKMSVQELKAWHRPQVECLAAAEADVLA 196
Query: 716 LETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVA 895
ETIP +EAE L +LL+EFP TKAWL+ SCKD + ++ G F+ + +QL+A
Sbjct: 197 FETIPSIKEAEALVELLKEFPNTKAWLSLSCKDVKRLSDGSLFRDAVQIA--NRSEQLIA 254
Query: 896 VGVNCCARSFVSNLMKGXNDDRPQAPXRLWL--P*FGRKYNPQIGXINRDKCXPXXITYR 1069
VGVNCC V L+ +P W+ P G ++P+ G + P +
Sbjct: 255 VGVNCCPPELVEPLLDSAR--TLLSPEISWVVYPNSGESWDPEQGWCTSEAALPALLEMS 312
Query: 1070 XGW 1078
W
Sbjct: 313 GTW 315
>UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 319
Score = 177 bits (430), Expect = 6e-43
Identities = 102/244 (41%), Positives = 150/244 (61%), Gaps = 10/244 (4%)
Frame = +2
Query: 209 SSENTEAPHI-VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGA 385
S+ +P I +++DG +T L H+G I G LWSA + + P+ + THLD+ RAGA
Sbjct: 7 STHLNSSPDIPLLIDGALATYLE-HLGADISGS-LWSASILLSRPDLIKKTHLDYYRAGA 64
Query: 386 DLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYL--------EEYRDYV 541
++ IT +YQAS+ G V+HLG+ + + +++ ++VQLA +AR Y+ E D
Sbjct: 65 NIAITASYQASIPGLVKHLGLGENEAKDVVKKSVQLAIEARDEYVQSKLEESCERSVDAA 124
Query: 542 QNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALE 721
+ + GSVGPYGA+L DGSEY G Y + E M+++HR R+QALV+AGVD+LA E
Sbjct: 125 SLREDLFVAGSVGPYGAYLSDGSEYRGDY--DVAHEAMKDFHRGRVQALVDAGVDVLACE 182
Query: 722 TIPCQEEAETLCDLLR-EFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAV 898
TIP + E E L DLL+ EF +AW F+ +D + IA G S +A +E +Q+V +
Sbjct: 183 TIPSRRETEALLDLLQSEFRDAEAWFTFTLRDAEHIADGTSLVDIA-ALFE-TAEQVVGL 240
Query: 899 GVNC 910
G NC
Sbjct: 241 GFNC 244
>UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG
protein - Bacillus subtilis
Length = 315
Score = 176 bits (429), Expect = 8e-43
Identities = 104/272 (38%), Positives = 156/272 (57%), Gaps = 2/272 (0%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
++VLDG +T+L ++ D LWSA+ + P + H D+ AGAD IT +YQ+
Sbjct: 13 LIVLDGAMATELERKGCNL--NDSLWSAKILMEEPELIKQVHTDYFAAGADCAITASYQS 70
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY--LEEYRDYVQNDDIPLIVGSVGPYG 589
+ EGF G+++ + LI +V +A +AR + LEE R N P+I S+GPYG
Sbjct: 71 TFEGFAAR-GLSEAEARRLIELSVSIAAEARDEFWSLEENR---LNRPKPIIAASIGPYG 126
Query: 590 AHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLR 769
A+L DGSEY G+YA S + + E+HRPR++AL+EAG D+LA ETIPC EA+ + LL+
Sbjct: 127 AYLADGSEYRGNYA--ISEDELIEFHRPRMKALIEAGADVLACETIPCLTEAKAIVRLLK 184
Query: 770 EFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMKGX 949
EFP T AW++FS KD I+ G A W Q+ A+G+NC + +L++
Sbjct: 185 EFPETYAWISFSAKDGLHISDGTPAADCAS--WLDEHRQIAALGINCTPLQHIPSLIEEL 242
Query: 950 NDDRPQAPXRLWLP*FGRKYNPQIGXINRDKC 1045
+ + P ++ P G +Y+P+ N C
Sbjct: 243 KKNTSK-PIIVY-PNSGEQYDPETKTWNGAAC 272
>UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=30;
Magnoliophyta|Rep: Homocysteine S-methyltransferase 3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 347
Score = 173 bits (421), Expect = 7e-42
Identities = 96/243 (39%), Positives = 144/243 (59%), Gaps = 10/243 (4%)
Frame = +2
Query: 242 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 421
V+DGGF+T+L H + DPLWSA+ + T P+ V HLD+L +GA++IIT +YQA++
Sbjct: 25 VVDGGFATELQRHGADI--NDPLWSAKCLITSPHLVTKVHLDYLESGANIIITASYQATI 82
Query: 422 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEE---------YRDYVQNDDIPLIVGS 574
+GFV G++ + L+ R+V++ +AR ++ Y I L+ S
Sbjct: 83 QGFVAK-GLSVGEAENLLRRSVEITYEAREIFYNRCTKGSWDFAYAGKASRRPI-LVAAS 140
Query: 575 VGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETL 754
VG YGA+L DGSEY G Y D+ S ET++++HR R+Q L ++G DL+A ETIP + EAE
Sbjct: 141 VGSYGAYLADGSEYSGIYGDSVSKETLKDFHRRRVQILAKSGADLIAFETIPNKLEAEAY 200
Query: 755 CDLLREFP-GTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVS 931
DLL E AW +F+ KD S+ G+S + AK +VA+G+NC A ++
Sbjct: 201 ADLLEEEDIDIPAWFSFTSKDGVSVPRGDSVVECAKVADSCK--NVVAIGINCTAPRYIH 258
Query: 932 NLM 940
L+
Sbjct: 259 ALI 261
>UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;
Bacteria|Rep: Homocysteine S-methyltransferase -
Escherichia coli (strain K12)
Length = 310
Score = 166 bits (403), Expect = 1e-39
Identities = 92/227 (40%), Positives = 136/227 (59%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
I++LDG +T+L ++ D LWSA+ + +P + HLD+ RAGA IT +YQA
Sbjct: 16 ILLLDGAMATELEARGCNLADS--LWSAKVLVENPELIREVHLDYYRAGAQCAITASYQA 73
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
+ GF G+ + Q LI ++V+LA++AR YL E Q + L+ GSVGPYGA+
Sbjct: 74 TPAGFAAR-GLDEAQSKALIGKSVELARKAREAYLAENP---QAGTL-LVAGSVGPYGAY 128
Query: 596 LHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF 775
L DGSEY G Y S+E + +HRPR++AL++AG DLLA ET+P E E L +LL +
Sbjct: 129 LADGSEYRGDYH--CSVEAFQAFHRPRVEALLDAGADLLACETLPNFSEIEALAELLTAY 186
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCA 916
P +AW +F+ +D + ++ G + V Q+VA+G+NC A
Sbjct: 187 PRARAWFSFTLRDSEHLSDGTPLRDVVALL--AGYPQVVALGINCIA 231
>UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;
Streptococcus|Rep: Homocysteine S-methyltransferase -
Streptococcus agalactiae H36B
Length = 351
Score = 165 bits (402), Expect = 1e-39
Identities = 98/254 (38%), Positives = 157/254 (61%), Gaps = 4/254 (1%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E E+ ++L G T+L G + G LWS +++ P + H D++RAGAD++
Sbjct: 43 ELLESKKALILHGALGTELESR-GCDVSGK-LWSDKYLIEDPAAIQTIHEDYIRAGADIV 100
Query: 395 ITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI-PLIVG 571
T+TYQA+++G + +GV++ Q +LI VQLAK R + +++ I PLI G
Sbjct: 101 TTSTYQATLQGLAQ-VGVSESQAEDLIRLTVQLAKAVREQVWKSLTKEEKSERIYPLISG 159
Query: 572 SVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAET 751
VGPY A L DGSEY G Y D E ++ +HR RI+ L++ GVDLLALETIP +EAE
Sbjct: 160 DVGPYAAFLADGSEYTGLY-DIYK-EGLKNFHRHRIELLLDEGVDLLALETIPNAQEAEA 217
Query: 752 LCDLL-REFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFV 928
L +LL +FP +A+++F+ +D ++I+ G + +AK +++P Q+VA+G+NC + S V
Sbjct: 218 LIELLVEDFPQVEAYMSFTSQDGKTISDGSAVAGLAKAI-DVSP-QVVALGINCSSPSLV 275
Query: 929 SNLMKGXND--DRP 964
++ ++ + D+P
Sbjct: 276 ADFLQAIAEQTDKP 289
>UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;
Actinomycetales|Rep: Homocysteine S-methyltransferase -
Mycobacterium tuberculosis
Length = 302
Score = 149 bits (360), Expect = 2e-34
Identities = 90/227 (39%), Positives = 129/227 (56%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+++ DGG +T+L GH + DPLWSAR + P+ + H + RAGA + T +YQA
Sbjct: 8 VLISDGGLATELEAR-GHDLS-DPLWSARLLVDAPHAITAVHTAYFRAGAQIATTASYQA 65
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
S EGF G+ + L+ R+V+LA+ AR D V + + SVGPYGA
Sbjct: 66 SFEGFAAR-GIGHDDATVLLRRSVELAQAAR--------DEVGVGGLS-VAASVGPYGAA 115
Query: 596 LHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF 775
L DGSEY G Y S+ + +WH PR++ LV+AG D+LAL+TIP +EAE L +L+R
Sbjct: 116 LADGSEYRGCYG--LSVAALMKWHLPRLEVLVDAGADMLALKTIPDIDEAEALVNLVRRL 173
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCA 916
T AWL+++ ++ A G+ ++VAVGVNCCA
Sbjct: 174 -ATPAWLSYTINGTRTRA-GQPLTDAFAVA--AGVPEIVAVGVNCCA 216
>UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1;
Janibacter sp. HTCC2649|Rep: Homocysteine
methyltransferase - Janibacter sp. HTCC2649
Length = 305
Score = 146 bits (354), Expect = 1e-33
Identities = 100/260 (38%), Positives = 140/260 (53%), Gaps = 1/260 (0%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
VVLDGGFST L GH + G LWSAR + P+EVV H F+ AGA+++I+ +YQAS
Sbjct: 23 VVLDGGFSTALEAR-GHDLSGR-LWSARLLRQAPSEVVAAHRTFVDAGAEIVISASYQAS 80
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
G+V G+T+E+ + +++LA+Q D L+ SVGPYGAHL
Sbjct: 81 HAGYVA-AGLTEEECDADLDASIELARQGA-------------DGRALVAASVGPYGAHL 126
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF- 775
DGSEY G A S T+RE+H R++ L+ AG DL+A+ETIP EAE + +LL E
Sbjct: 127 ADGSEYTGYPA--VSRATLREFHSRRLERLIAAGPDLVAVETIPEVAEAEVVVELLTEIA 184
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMKGXND 955
P W++FS + G F + + +AVGVNC A + L++
Sbjct: 185 PDLPYWVSFSATGGGRLTGGAPFAEAI----GVVRGAAIAVGVNCTAPRHIDELLEAGG- 239
Query: 956 DRPQAPXRLWLP*FGRKYNP 1015
P P ++ P G Y+P
Sbjct: 240 --PNVPYVIY-PNAGATYDP 256
>UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2;
Bacteria|Rep: Homocysteine S-methyltransferase -
Lactobacillus plantarum
Length = 309
Score = 145 bits (352), Expect = 2e-33
Identities = 90/225 (40%), Positives = 126/225 (56%), Gaps = 1/225 (0%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
VV DG +T+L V LWSA + HP+ + H +L AGA ++ TNTYQA+
Sbjct: 13 VVSDGAMATELEKR--GVATNSALWSATAMLDHPDAIQAVHQSYLDAGAKIMTTNTYQAN 70
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
V F E G+ Q +LI +AV +A AR +V + +I GS+GPYGA+L
Sbjct: 71 VPAF-EQAGIAAVQARQLIQQAVTIAHTARD------ASHVTD---AVIAGSIGPYGAYL 120
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLL-REF 775
DGSEY G+Y T S +++HR R+ ++ AGVD+LALET+P +E + L L+ +
Sbjct: 121 ADGSEYTGAYQLTPS--AYQDFHRERLALIMAAGVDVLALETMPRLDEVQALVQLITTTW 178
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
P W++FS KD Q++ G S AK W +VAVGVNC
Sbjct: 179 PQQPYWVSFSIKDPQTLCDGTSLAVAAK--WVAAQPNVVAVGVNC 221
>UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Leishmania|Rep: Homocysteine
S-methyltransferase, putative - Leishmania major
Length = 339
Score = 144 bits (350), Expect = 3e-33
Identities = 90/230 (39%), Positives = 133/230 (57%), Gaps = 4/230 (1%)
Frame = +2
Query: 233 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 412
++V+LDGG +T+L + DPLWS + + P ++ N L +LRAGA IIT +YQ
Sbjct: 29 YVVMLDGGLATELETRGCDL--RDPLWSGKVLLESPQQLQNVALAYLRAGARCIITASYQ 86
Query: 413 ASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGA 592
+ + +EH +T++ I +V++A+ AR +L R+ Q I + GSVGPYGA
Sbjct: 87 ITPQSLMEHRRLTEDAAVAAIEESVRIAQSARERHL---REKPQAAPI-FVAGSVGPYGA 142
Query: 593 HLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLR- 769
+L DGSEY G Y S E +E+HR RI AL+ AG D+LA+ET P E + LL+
Sbjct: 143 YLADGSEYRGDY--VRSAEEFKEFHRLRIAALLRAGADVLAIETQPSAAEVRAIVALLQE 200
Query: 770 EFPGTKAWLAFS---CKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
E P +AW++F+ ++I+ G + + E P Q+VAVGVNC
Sbjct: 201 EHPNCRAWVSFTTSRISPVEAISDGTKWADII-SFLEKAP-QIVAVGVNC 248
>UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1; Vitis
vinifera|Rep: Putative uncharacterized protein - Vitis
vinifera (Grape)
Length = 347
Score = 125 bits (301), Expect(2) = 3e-31
Identities = 82/242 (33%), Positives = 129/242 (53%), Gaps = 22/242 (9%)
Frame = +2
Query: 359 HLDFLRAGADLIITNTYQA-SVEGFVEHL---GVTKEQGYE-----LIARAVQLAKQART 511
HLD+L AGAD+IIT +YQ S +V L G+ E E + ++V++A +AR
Sbjct: 90 HLDYLEAGADIIITASYQVNSAYIYVNRLLFRGLKLEASLEEKVKPCLGKSVEIACEARK 149
Query: 512 LYLEEYRDYVQNDDIP---------LIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREW 664
+Y + ++ +D L+ SVG YGA+L DGSEY G Y D ++ET++++
Sbjct: 150 MYYDRCIEFACDDXEDGRILKHRPILVAASVGSYGAYLADGSEYSGIYGDEITVETLKDF 209
Query: 665 HRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFP-GTKAWLAFSCKDDQSIAHGES 841
HR R+Q L +AG DL+A ET+P + EA+ +LL E AW +F+ KD + G+S
Sbjct: 210 HRRRVQILADAGADLIAFETVPNKLEAQAYAELLEEENIKIPAWFSFNSKDGVHVVSGDS 269
Query: 842 FQK---VAKKCWELNPDQLVAVGVNCCARSFVSNLMKGXNDDRPQAPXRLWLP*FGRKYN 1012
+ +A+ C ++V+VG+NC F+ L+ + L P G Y+
Sbjct: 270 LLECVSIAESC-----KKVVSVGINCTPPRFIHGLILSIK--KVTTKPILIYPNSGESYD 322
Query: 1013 PQ 1018
P+
Sbjct: 323 PE 324
Score = 34.3 bits (75), Expect(2) = 3e-31
Identities = 17/49 (34%), Positives = 29/49 (59%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAG 382
+ V+DGG +T+L H + DPLWSA+ + + P+ ++ T F+ G
Sbjct: 22 VAVIDGGLATELERHGADL--NDPLWSAKCLLSSPH-LIRTGSRFVNLG 67
>UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus reuteri|Rep: Homocysteine
S-methyltransferase - Lactobacillus reuteri F275
Length = 310
Score = 134 bits (323), Expect = 6e-30
Identities = 82/225 (36%), Positives = 130/225 (57%), Gaps = 1/225 (0%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
+++DG ST L +G + LW+A + P V H ++ +AG L IT+TYQA+
Sbjct: 12 LLIDGAMSTALE-QLG-ADTNNSLWTASVLANQPALVKKVHQEYFKAGDRLAITDTYQAN 69
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
V F+++ G +K++ + LI RAV LAK+AR Y +E Y + G++GPYGA+L
Sbjct: 70 VPAFIKN-GYSKQEAHSLIQRAVVLAKEARDEYQQETGIY------NYVAGALGPYGAYL 122
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF- 775
+GSEY G+Y ++IE +++HRPR+ ++ GVD++A+ET P +E DL++E
Sbjct: 123 ANGSEYSGAY-HLSTIE-YQQFHRPRLTDILTVGVDVIAIETQPRLDEVLAELDLVKELA 180
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
P T +++FS KD + G A+ + + AVGVNC
Sbjct: 181 PDTLCYVSFSLKDSTHLPDGTPLAVAARTVAKYT--NVFAVGVNC 223
>UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus delbrueckii subsp. bulgaricus|Rep:
Homocysteine S-methyltransferase - Lactobacillus
delbrueckii subsp. bulgaricus (strain ATCC 11842 /
DSM20081)
Length = 310
Score = 132 bits (319), Expect = 2e-29
Identities = 89/262 (33%), Positives = 143/262 (54%), Gaps = 1/262 (0%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
V LDG ST L G + D LW+A+ + +P+ V H ++ +AGA + IT++YQAS
Sbjct: 13 VTLDGSMSTPLEAW-GEDTNSD-LWTAKALADNPDLVYRVHQEYFKAGARVTITDSYQAS 70
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
+ F++H G++++ LI + +A +AR + E + N + GSVGPYGA+L
Sbjct: 71 LPAFMKH-GLSEDAARALIRESAAVAIKARDDF--EKETGIHN----FVAGSVGPYGAYL 123
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLR-EF 775
DGSEY G YA S E ++H PRI+ LV GVD LA+ET P E + D L+ ++
Sbjct: 124 ADGSEYRGDYA--LSHEEYVDFHAPRIEELVAGGVDCLAVETQPKLSEVRAILDYLKAKY 181
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMKGXND 955
P +++FS KD +I+ G + ++ Q+ A G NC ++ +++K N
Sbjct: 182 PDLPVYVSFSLKDPATISEGLPLTEAVEEVSAY--AQVFAAGANCFKLAWTVDVVK--NL 237
Query: 956 DRPQAPXRLWLP*FGRKYNPQI 1021
+ P ++ P G +Y+P +
Sbjct: 238 RASKLPIVVY-PNSGAEYDPSV 258
>UniRef50_UPI000050FD2A Cluster: COG2040:
Homocysteine/selenocysteine methylase
(S-methylmethionine-dependent); n=1; Brevibacterium
linens BL2|Rep: COG2040: Homocysteine/selenocysteine
methylase (S-methylmethionine-dependent) -
Brevibacterium linens BL2
Length = 308
Score = 129 bits (312), Expect = 1e-28
Identities = 90/235 (38%), Positives = 120/235 (51%), Gaps = 4/235 (1%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
+V+DGG T L G + + LWSA + P+ + H DF+RAGA ++ T +YQA+
Sbjct: 19 LVIDGGLGTALESR-GIDLSHE-LWSAALLRDSPDTLAEVHADFIRAGAQIVTTASYQAT 76
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
GF E + E+G LIAR+V++A A L+ GSVGPYGA L
Sbjct: 77 PLGF-ERASIPAEEGLRLIARSVEIAAGAGDA---------------LVAGSVGPYGAAL 120
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFP 778
+G+EY G Y S E +HRPRI+ALV AG DLLA+ET P E L L E+
Sbjct: 121 GNGAEYTGDYH--LSDEEFAAFHRPRIEALVNAGADLLAIETQPSLSEITVLAGLADEY- 177
Query: 779 GTKAWLAFSCKDDQSIAHGESF--QKVAKKCWELNPD--QLVAVGVNCCARSFVS 931
G AWL+ + D +A G + E D + AVGVNC S V+
Sbjct: 178 GIPAWLSVTLADQGDLADGSHMADRTPLSDLAEAVADSRMIRAVGVNCVRPSLVA 232
>UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4;
n=1; Candida albicans|Rep: Putative uncharacterized
protein SAM4 - Candida albicans (Yeast)
Length = 311
Score = 128 bits (309), Expect = 3e-28
Identities = 74/237 (31%), Positives = 127/237 (53%), Gaps = 4/237 (1%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVG----HVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNT 406
+V+DG T+L + ++ G PLWS + + +P V HLD++ GAD+IIT+T
Sbjct: 13 LVIDGALGTELERLLPTTSTYLPSGSPLWSGQVLIKNPELVEQVHLDYINVGADMIITST 72
Query: 407 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 586
YQ S +++G +Q L A+ +AK A + RD V +I GS+GPY
Sbjct: 73 YQTSYASLHKYIGYDMDQAIALWNSALNVAKNA---VKKSGRDDV------IIAGSIGPY 123
Query: 587 GAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLL 766
L +GSEY+G Y T E + E+H P + + VD++ +ETIP +E + + L
Sbjct: 124 ATLLANGSEYNGDYQGVTD-EELIEYHTPLFEFYENSDVDIICIETIPSFQELKVIIGLA 182
Query: 767 REFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNL 937
+++ + +++ + + +++ G S +VA+ E+N + VAVG+NC + V +
Sbjct: 183 KKYTSKEFFISINPQTGSALSDGTSLIEVAQLFAEINDPRFVAVGINCTSYENVDQI 239
>UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus|Rep: Homocysteine S-methyltransferase -
Lactobacillus acidophilus
Length = 310
Score = 127 bits (306), Expect = 6e-28
Identities = 80/225 (35%), Positives = 125/225 (55%), Gaps = 1/225 (0%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
++LDG ST L V + LW+A + ++V H+++ ++GA + ITNTYQA+
Sbjct: 12 LILDGAMSTALEKQ--GVNTNNDLWTAVALENDLDKVYKVHMNYFKSGAQMTITNTYQAN 69
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
V+ F +H G + E +LI AVQ+AK+AR ++Y+ Q + SVGPYGA+L
Sbjct: 70 VQAFKKH-GYSDEHTKKLITDAVQIAKKAR----DDYQ--TQTGKHNWVAASVGPYGAYL 122
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFP 778
DG E+ G Y+ T + +H PR++ L+E D LA+ET P +E + D L+E+
Sbjct: 123 SDGDEFRGDYSLTP--KEYLAFHLPRLKILLENKPDCLAIETQPKLDEVIAILDWLKEYA 180
Query: 779 G-TKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
++ F+ D I+ G +KV +K E +Q+ AVG NC
Sbjct: 181 NQIPVYVTFTLHDTTKISDGTPLKKVMQKLNEY--EQVFAVGANC 223
>UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep: Homocysteine
S-methyltransferase - Granulobacter bethesdensis (strain
ATCC BAA-1260 / CGDNIH1)
Length = 313
Score = 126 bits (305), Expect = 8e-28
Identities = 81/236 (34%), Positives = 125/236 (52%), Gaps = 1/236 (0%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
++LDG +T+L G+ +D DPLWS R + +P + H +L AGAD I T +YQ S
Sbjct: 15 LLLDGALATELE-RAGYHLD-DPLWSGRLLLDNPAAIAAVHRAYLEAGADCIETASYQLS 72
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQAR-TLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
+ G ++ G+++ + ++A A +LA R ++ +N PL+ GS+GPYGA
Sbjct: 73 LPG-LQRRGLSRGRAMSVLADAARLACSVRDDVWAGLPAAQRRNRIRPLVAGSLGPYGAC 131
Query: 596 LHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF 775
DGSEY G YA S +H PR++AL G DL+A ET+P +EA DLL+
Sbjct: 132 QADGSEYTGRYA--LSRSQYLAFHAPRMRALAAGGADLIACETVPHLDEALAFADLLQAL 189
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMK 943
W++FS +D IA G + + + + A+G+NC V L++
Sbjct: 190 -SVPGWVSFSVRDAAHIADGTPLRLCVQAM--ASCPFVAAIGINCTDPVLVPALIR 242
>UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Homocysteine
methyltransferase - Plesiocystis pacifica SIR-1
Length = 325
Score = 117 bits (281), Expect = 7e-25
Identities = 89/234 (38%), Positives = 125/234 (53%), Gaps = 11/234 (4%)
Frame = +2
Query: 242 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 421
VLDGG +T L G +D DPLWSAR + P + H + AGAD++ T +YQAS+
Sbjct: 22 VLDGGLATSLEA-CGCDLD-DPLWSARLLLDDPEALRTVHRRWRDAGADILATASYQASL 79
Query: 422 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLH 601
G + G+++ + L+ +V L + A +E N PLI SVG YGA+L
Sbjct: 80 PG-LRAKGLSEARAKALLRESVTLTRAAA----DE-----ANAPRPLIAASVGSYGAYLA 129
Query: 602 DGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEE----AETLCDLLR 769
DGSEY G Y S+E + ++HRPR+ L AG DL+A ET P E AE L +LL
Sbjct: 130 DGSEYRGGYG--LSVEALADFHRPRLLELAAAGPDLIAFETFPDAVELAALAELLTELLT 187
Query: 770 EFPGT--KAWLAFSCK---DDQSI--AHGESFQKVAKKCWELNPDQLVAVGVNC 910
E T +AW++ S D+S+ A G K + +P ++ A+GVNC
Sbjct: 188 ELGDTLPRAWISASLSPPGPDRSVRLADGTPLTKALAPLTD-HP-KVAALGVNC 239
>UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransferase;
n=1; Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305|Rep: Putative homocysteine S-methyltransferase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 301
Score = 116 bits (278), Expect = 2e-24
Identities = 81/268 (30%), Positives = 136/268 (50%), Gaps = 2/268 (0%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E +A +VLDGG +T L G + LWS+ + +P ++ H F GAD++
Sbjct: 5 EKLKAQSPLVLDGGLATTLE-QAGCSLKTS-LWSSEVLKNNPTQIKQAHQAFTDVGADIL 62
Query: 395 ITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGS 574
+T+TYQAS + F + +G+ + +L AV +A T D +IVGS
Sbjct: 63 LTSTYQASYQTFSD-IGMKATEIDQLYNTAVNQIMEATT-------------DTQVIVGS 108
Query: 575 VGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETL 754
+GPYGA+L DGSEY G+Y S E ++H+ RI+ALV+ G++ ET+P EE + +
Sbjct: 109 LGPYGAYLSDGSEYTGAY--DLSKEDYFQFHKTRIEALVKRGINDFVFETVPNFEEIKAI 166
Query: 755 CD-LLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVS 931
+ ++ + WL+ + +D ++ F+K+ + +++ G+NC S V+
Sbjct: 167 VEYIVPHYTNQTFWLSVTVNEDGDLSDDTEFEKLCAYIKQY-AERIPVFGINC---SSVA 222
Query: 932 NLMKGXNDDRPQAPXRLWL-P*FGRKYN 1012
+ K + P + L P G +YN
Sbjct: 223 GINKAISKGLKNVPQTIALYPNGGAQYN 250
>UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to
5-methyltetrahydrofolate:homocysteine methyltransferase;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to 5-methyltetrahydrofolate:homocysteine
methyltransferase - Strongylocentrotus purpuratus
Length = 172
Score = 110 bits (264), Expect = 8e-23
Identities = 57/120 (47%), Positives = 72/120 (60%), Gaps = 8/120 (6%)
Frame = +2
Query: 653 MREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAH 832
+++WHRPRIQALV+ VDLLA+ETIP EAE L +L+EFP KAWL F CKD I H
Sbjct: 6 LKQWHRPRIQALVDGKVDLLAIETIPSIVEAEALLSVLQEFPSMKAWLTFYCKDKSHIGH 65
Query: 833 GESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMKGXNDDR--------PQAPXRLWL 988
GESF + K + Q+V VG NC A V+ L++G + R P AP W+
Sbjct: 66 GESFAEAVGKVSACS--QIVGVGTNCIAAENVTALLQGASTSRNGKPFVVYPNAPGEQWI 123
>UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 326
Score = 108 bits (260), Expect = 2e-22
Identities = 72/246 (29%), Positives = 122/246 (49%), Gaps = 12/246 (4%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVG----HVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNT 406
VVLDG T L + ++ PLWS + + P + H ++ AG+++I T+T
Sbjct: 10 VVLDGALGTALEDLIDPSAPYLPSKSPLWSGQVLLDAPELIQKVHEMYIGAGSEVIFTST 69
Query: 407 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI------PLIV 568
YQ S + +H ++ EQ E+ R++ L + A L ++E Y + + I
Sbjct: 70 YQLSYDSLRKHTTLSDEQILEVWQRSIDLVR-AAALSIDETARYTKEKESRGEPGKVHIA 128
Query: 569 GSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVE-AGVDLLALETIPCQEEA 745
GS+GPY A+L +GSEY G Y + T E + +H P ++ E VDL+A ETIP +E
Sbjct: 129 GSIGPYAAYLANGSEYTGDYGNVTD-EQLEAFHTPMLEFFTENEAVDLIAFETIPNFQEL 187
Query: 746 ETLCDLLREFPGTKAWL-AFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARS 922
+ + L++ K L + +C++ ++ G +V K P + +G+NC +
Sbjct: 188 KAVTKLVKRLNCKKPVLFSITCQNLDNLTDGTPLLEVKKYLDFCLPKEQKILGINCVEYT 247
Query: 923 FVSNLM 940
V +M
Sbjct: 248 LVQGIM 253
>UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome A of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 351
Score = 105 bits (251), Expect = 3e-21
Identities = 74/262 (28%), Positives = 131/262 (50%), Gaps = 23/262 (8%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGD-------PLWSARFIHTHPNEVVNTHLDFLRAGADLII 397
+V+DG TQL ++ D PLWSA + +P + H D++ +GA++I
Sbjct: 14 LVIDGALGTQLETKFSKLLQQDNINIQTHPLWSALVLLKNPELIQEVHYDYMCSGANIIT 73
Query: 398 TNTYQASVEGFVEHL-GVTKEQGYELI-ARAVQLAKQARTLYLEEY---RDYVQNDDIPL 562
T+TYQAS G +E+ G+ + + +A++LA AR+ YLE + + N +I
Sbjct: 74 TSTYQASKRGLLEYAPGIENDDEVNAVYDKAIELAVDARSQYLENMGKGMNTLTNKEI-F 132
Query: 563 IVGSVGPYGAHLHDGSEYDGSY-ADTTSIETMREWHRP-RIQALVEAGVDLLALETIPCQ 736
I GS+GP+GA+L +G+EY G Y + T + ++++H Q + D++ ETIP
Sbjct: 133 ICGSIGPFGAYLANGAEYTGKYGSHITEPQELKKFHYDITSQFISNPKCDIIGFETIPNY 192
Query: 737 EEAETLCDLLREF---PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWE--LNPDQL---- 889
E + + L+ E +++ + KD ++I G +V E N ++L
Sbjct: 193 SEFQQIVHLMEELLQKTNKPFYISLNFKDPKTICDGTPITQVVDYLNERLSNNEKLRSAF 252
Query: 890 VAVGVNCCARSFVSNLMKGXND 955
+ +G NC +N++ +D
Sbjct: 253 IGLGCNCVPLEIATNILLNMSD 274
>UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 313
Score = 94.7 bits (225), Expect = 4e-18
Identities = 70/249 (28%), Positives = 120/249 (48%), Gaps = 14/249 (5%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHV---GHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 409
+VLDGG QL + DPLWS R + P+ + + H FL AG D++ T+TY
Sbjct: 7 LVLDGGLGIQLETLAEKRNFAVKNDPLWSGRALIEAPDLIEDVHKSFLEAGCDIVTTSTY 66
Query: 410 QASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYG 589
Q S ++ T Q EL A++V + QA + + R + G++GPYG
Sbjct: 67 QISRASLKKYTDFTDAQIEELWAKSVDVCWQACKFHESKAR----------VCGAIGPYG 116
Query: 590 AHLHDGSEYDGSYADTTSIETMREWHRPRIQAL-VEAGVDLLALETIPCQEEAETLCDLL 766
L + +EY G Y T+ + ++H P L VD+LA ETIP +E + + +L+
Sbjct: 117 GFLANYAEYTGEYGLITN-HKLEQYHLPLATFLNNNPKVDILAFETIPNYKELKVIVNLV 175
Query: 767 REFPGT----KAWLAFSCKDDQSIAHGESFQKVAKKC-WELNPD-----QLVAVGVNCCA 916
+ T +L+ + ++ ++ G +K+ +LN + +L+A+G NC
Sbjct: 176 CKMSATGPLKPFYLSMNFRNSSQMSDGTPIEKIMGYLNGKLNKNRTLRKRLIAIGCNCTE 235
Query: 917 RSFVSNLMK 943
++++K
Sbjct: 236 LKDATHVLK 244
>UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase; n=1;
Pichia stipitis|Rep: AdoMet-homocysteine
methyltransferase - Pichia stipitis (Yeast)
Length = 337
Score = 89.4 bits (212), Expect = 2e-16
Identities = 74/282 (26%), Positives = 130/282 (46%), Gaps = 22/282 (7%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVID----GDPLWSARFIHTHPNEVVNTHLDFL-RAGADLIITN 403
+VLDG T+L + PLWS + PN + N H ++L +A D +I++
Sbjct: 13 LVLDGAMGTELEACIPKDSKIQPRKHPLWSGLVLLNEPNLIKNVHYNYLEQADVDALISS 72
Query: 404 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPL-IVGSVG 580
TYQ S EH + EQ + +++ + + A + +YR N + I+GS+G
Sbjct: 73 TYQISYPSLKEHTDLDDEQIRGIWKKSIDVVEDA----ILQYRSKNSNSKKKIYIIGSIG 128
Query: 581 PYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQ-ALVEAGVDLLALETIPCQEEAETLC 757
PY +L DGSEY G Y + + + + +H+P ++ L + VD + ETIP +E + +
Sbjct: 129 PYATYLADGSEYTGDYKNASDSD-IESYHQPLLEYFLGDDRVDTIGFETIPSFQEVKVVL 187
Query: 758 DLLREFPGTKA-----WLAFSCKDDQSIAHGESFQKVAKKC------WELNPDQLVAVGV 904
LL + +++F+ D+ +I G + V + +V +G+
Sbjct: 188 KLLSHLFAEQEKRKYYYISFNF-DEATITDGTPTEVVISYIDSFLDKYPFLRKYMVGLGL 246
Query: 905 NCCARSFVSNLMKGXNDDRPQAPXRLW----LP*FGRKYNPQ 1018
NC + +++ ND + A L+ P F KY P+
Sbjct: 247 NCIDYHKIGSIVAKINDSQTSAQKPLFPLIVYPNFTIKYVPE 288
>UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 348
Score = 83.8 bits (198), Expect = 8e-15
Identities = 65/222 (29%), Positives = 107/222 (48%), Gaps = 8/222 (3%)
Frame = +2
Query: 281 VGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTK-E 457
V +D P W + N + H D++ AGAD++ + +YQAS+EG ++ V +
Sbjct: 58 VNRALDEHPEW-LESSQDNSNLLYRIHKDYVVAGADIVTSASYQASLEGTIKAGAVQRWP 116
Query: 458 QGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADT 637
+ ++ ++ QL ++A T + + L+ SVGP+GA L G EY+G Y
Sbjct: 117 EALWMLRKSEQLVRKAVTEAKVKRK--------VLLAASVGPFGAWLGGGQEYNGDYTGY 168
Query: 638 TSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF--PG-TKAWLAFSC 808
T + +R H +I+A++ D+L +ETIP E E L D+L P L+ S
Sbjct: 169 TK-DDIRRHHEFKIRAVLGGSPDMLLIETIPSIIEVEVLVDVLNTILPPSPIPVCLSLSV 227
Query: 809 K----DDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARS 922
K D ++A G +A+ + +GVNCCA +
Sbjct: 228 KSADYDRVALADGSELSNIAELA--ASCPSFTHLGVNCCAET 267
>UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 323
Score = 82.6 bits (195), Expect = 2e-14
Identities = 59/240 (24%), Positives = 112/240 (46%), Gaps = 2/240 (0%)
Frame = +2
Query: 302 DPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIAR 481
D W + + N + + D++ +G+ ++ T TYQ S H V +GY+ + R
Sbjct: 47 DDFWDSETKTSDRNIIEGIYRDYITSGSRILSTITYQTSFALISTHTEVKTIEGYKQLIR 106
Query: 482 AVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMRE 661
+ T + R + D+ ++GS+GP+GA L G+EY G+Y D+ S E
Sbjct: 107 NI-------TSFC---RSAIGEDN--YLIGSIGPFGARL--GAEYTGNYGDSPSNINYLE 152
Query: 662 WHRPRIQAL-VEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGE 838
+ +P+++ +D++ ET+P + E E + + +++ S D+ + G
Sbjct: 153 YFKPQLEEFNNNDDIDIIGFETVPNKYELEAILSWDKSVISKPYYVSLSLLDNGGLRDGT 212
Query: 839 SFQKVAKKCWEL-NPDQLVAVGVNCCARSFVSNLMKGXNDDRPQAPXRLWLP*FGRKYNP 1015
SF+++A + N D L+ G NC + + S + + P P ++ P G Y+P
Sbjct: 213 SFEEIATIFKKYSNNDNLILTGANCISFKYASENISKLHQAIPTLPLIVY-PNSGEIYDP 271
>UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;
Schizosaccharomyces pombe|Rep: Uncharacterized protein
C57A7.07c - Schizosaccharomyces pombe (Fission yeast)
Length = 308
Score = 81.0 bits (191), Expect = 5e-14
Identities = 68/245 (27%), Positives = 116/245 (47%), Gaps = 9/245 (3%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+++LDGG ST + + I LW++ + +P VV H +FL+ D+I T TYQ
Sbjct: 1 MLMLDGG-STAILPKLPESISESRLWTSEALVRYPEIVVKHHEEFLKV-CDIISTFTYQL 58
Query: 416 SVEGFVEHL-GVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGA 592
+ E + GV +Q Y A ++ L +Y E+ + N I L +GS + A
Sbjct: 59 DASIYDEKVEGVPLKQVY---ANSIGLP-----VYAREHLG-LPNKYIALCLGS---HAA 106
Query: 593 HLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAG------VDLLALETIPCQEEAETL 754
+ EY Y T E + +H+ RI+A+ + +D +A E++P EAE +
Sbjct: 107 TIPGCMEYKMIYDKPTDFEMLYNFHKNRIEAIQASNPKAFEKIDFIAFESLPHVTEAEVV 166
Query: 755 CDLLREFPG--TKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFV 928
C L+++ G + W+ +C + +I E + K +N D + +GVNC S +
Sbjct: 167 CQLIQDMKGWSKRCWITCTCPERSTI---ERVSSIISKILSINHDSIWGIGVNCFHLSLL 223
Query: 929 SNLMK 943
+ K
Sbjct: 224 EPIAK 228
>UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 448
Score = 80.2 bits (189), Expect = 1e-13
Identities = 66/198 (33%), Positives = 99/198 (50%), Gaps = 28/198 (14%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEV---------VNTHLDFLRAGAD 388
I +LDGG +T L + + PLWSAR + ++V + HL +L+AGA
Sbjct: 19 IGILDGGLATYLEDGLDFDLSKGPLWSARLLDEKEDDVSDGKGQKGIFDAHLHYLQAGAG 78
Query: 389 LIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY-LEEYRDYVQN--DDIP 559
+I T TYQAS+E F + L+++AV LA A + + + V + P
Sbjct: 79 IIGTATYQASLESFAR-ANYDQVSASHLMSKAVDLACDALHAHNISNNKVGVASAASARP 137
Query: 560 LIVGSVGPYGAHLHDGSEYDGSYADT------------TSIETMREWHRPRIQALVE--- 694
L+ S+GPYGA L +G+EY G Y T S+E M +H+ RI+A +
Sbjct: 138 LLSLSLGPYGAMLSNGAEYTGDYRRTFLAESDPLREQQPSLEEMMAFHQRRIEAFIAQPS 197
Query: 695 -AGVDLLALETIPCQEEA 745
V +LA+ET+P +EA
Sbjct: 198 WEHVGVLAVETVPRADEA 215
>UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 369
Score = 74.9 bits (176), Expect = 4e-12
Identities = 60/187 (32%), Positives = 81/187 (43%), Gaps = 16/187 (8%)
Frame = +2
Query: 236 IVVLDGGFSTQLS-CHVGHVIDGDPLWSARFI---HTH-PNEVVNTHLDFLRAGADLIIT 400
I +LDGG T L H + +PLWS++ + H H P ++ T F+ AGAD+++T
Sbjct: 7 IHLLDGGLGTTLGDSHQVQFTEKEPLWSSQLLIPTHPHGPKTLLATQKSFVDAGADILLT 66
Query: 401 NTYQASVEGF-----VEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLI 565
TYQ S EGF H + G + + + + D I
Sbjct: 67 ATYQTSYEGFGGSGYAVHSHSSSNSGKADGDKEEVNGIMRSAVDIASDAFSTKKDSNGKI 126
Query: 566 VGSVGPYGAHLHDGSEYDGSYADT-TSIETMREWHRPRIQALVE-----AGVDLLALETI 727
S+G YGA + G EY G Y D S E + WH RI VD +A ETI
Sbjct: 127 ALSLGAYGAIMTPGQEYTGKYDDDHKSSEQLSSWHHERISVFSRDPKCWERVDYVAFETI 186
Query: 728 PCQEEAE 748
P EE E
Sbjct: 187 PLLEEIE 193
>UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;
Pezizomycotina|Rep: Contig An15c0240, complete genome -
Aspergillus niger
Length = 353
Score = 74.9 bits (176), Expect = 4e-12
Identities = 74/262 (28%), Positives = 118/262 (45%), Gaps = 22/262 (8%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGD--PLWSARFIHTHPNEVVNTHLDFLRAGA-DLIITNT 406
I++LDGG T L H PLWS+ + + P+ +++ DF A D+++T T
Sbjct: 6 ILILDGGLGTSLQDHYNITFSSSTTPLWSSHLMISDPSTLLSCQRDFTTTAAVDVLLTAT 65
Query: 407 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 586
YQ S EGF TK + +A RT L+ VQN + + S+GPY
Sbjct: 66 YQVSPEGFQR----TKTPSHPTGIPRESIAGYLRTA-LDVAGQAVQNTSASVAL-SLGPY 119
Query: 587 GAHLHDGSEYDGSY-ADTTSIETMREWHRPRI-----QAL--VEAG--VDLLALETIPCQ 736
GA + G EY G Y + + E + WH R+ +A+ + G V +A+ET+P
Sbjct: 120 GACMIPGQEYSGKYDGEHDTEEKLWRWHTDRLGLFNDEAMEGMRLGERVKYIAMETVPRI 179
Query: 737 EEAETLCDLL---REFPGTKAWLA--FSCKDDQSIAHGESFQKVAKKCWELNPDQLVA-- 895
+E + + R G W+A F +D ++ G + +V + L P + A
Sbjct: 180 DEVRAVRRAVGSSRFCEGIPFWVACVFPIEDKDTLPDGSTVDEVVEAA--LLPIEGGATP 237
Query: 896 --VGVNCCARSFVSNLMKGXND 955
+G+NC + L+K D
Sbjct: 238 WGIGINCTKLHKLPRLVKLFGD 259
>UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Filobasidiella neoformans|Rep:
Homocysteine S-methyltransferase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 381
Score = 74.1 bits (174), Expect = 6e-12
Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 3/164 (1%)
Frame = +2
Query: 233 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 412
+I+VLDGG T L +G I PLW + + T+P+ + H +++ GADL+ T TYQ
Sbjct: 4 NILVLDGGMGTTLES-LGVDISS-PLWGSEALRTNPDVIRKVHEGYVQGGADLVETATYQ 61
Query: 413 ASVEGFVEHLGVTKEQGYELIARAVQLAKQ---ARTLYLEEYRDYVQNDDIPLIVGSVGP 583
+ + +HL +E+ ++ V+L + + EE+ + + +V S GP
Sbjct: 62 LTPQNLCDHLHCPREEAECILCSGVKLVASCIASCSSRNEEHNTKSKGGNKSKVVLSFGP 121
Query: 584 YGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLA 715
YG+ L G EY G Y T P EA + LA
Sbjct: 122 YGSTLQPGQEYGGIYPPPFGPSTSTNAFPPDSNDEEEAAIQALA 165
>UniRef50_Q2TXK9 Cluster: Predicted protein; n=2;
Trichocomaceae|Rep: Predicted protein - Aspergillus
oryzae
Length = 376
Score = 73.3 bits (172), Expect = 1e-11
Identities = 56/183 (30%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVI--DGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 409
I++LDGG T L ++ PLWSA + + P+ + H F GAD+I+T TY
Sbjct: 8 ILLLDGGLGTTLGDPPHNITFTAETPLWSAHLLISSPSTLEEVHKAFATVGADIILTATY 67
Query: 410 QASVEGF-VEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 586
Q S EGF + T + + A+ LA++A + + + S+GPY
Sbjct: 68 QTSFEGFTLTDPRYTADDAAHFMRSAIPLARRAGS----------SSGRTVKVALSLGPY 117
Query: 587 GAHLHD-GSEYDGSYADTTSIET-MREWHRPRIQALV-EAG----VDLLALETIPCQEEA 745
GA + G+EY G Y + + E +REWH R+ V E G + +A ET+ +E
Sbjct: 118 GATMSPVGAEYTGLYPEEMNSEAKLREWHARRLCVFVDETGSWDNFEYIAFETVRRADEV 177
Query: 746 ETL 754
+ +
Sbjct: 178 KAI 180
>UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1785
Score = 70.9 bits (166), Expect = 6e-11
Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 13/168 (7%)
Frame = +2
Query: 230 PHIVVLDGGFSTQLS-CHVGHVIDGD-PLWSARFIHTHPNEVVNTHLDFLRAGADLIITN 403
P+I++LDG T L G PLWS+ + +HP + H ++ AGAD+++T
Sbjct: 6 PNILLLDGAMGTVLEEPPYGFTFSAQTPLWSSHLLLSHPTTLSEIHRSYVDAGADIVLTA 65
Query: 404 TYQASVEGFVEHLGV---------TKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI 556
TYQAS EGF V E+ R + + R+ Y + +
Sbjct: 66 TYQASFEGFARTAIVPANVPADHKQDERDGHATYRPMDATRYMRSAIPLAYSSFNFSSKP 125
Query: 557 PLIVGSVGPYGAHLHD-GSEYDGSYADTTS-IETMREWHRPRIQALVE 694
P + S+GPYGA + +EY G Y + S + WH R++ +E
Sbjct: 126 PRVALSLGPYGATMCPVSAEYTGIYPEEMSNTAALEAWHANRLKVYME 173
>UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein
NCU00799.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00799.1 - Neurospora crassa
Length = 361
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/267 (25%), Positives = 116/267 (43%), Gaps = 27/267 (10%)
Frame = +2
Query: 236 IVVLDGGFSTQLS-CHVGHVIDGDPLWSARFIHT-HPNEVVNTHLDFLRAGADLIITNTY 409
+ +LDGG T L H PLWS+ + + +++ + H F +AGA++I T TY
Sbjct: 7 VQILDGGMGTTLEDMHDITFSFETPLWSSHLLVSGEEDKLSDCHEAFKQAGANIISTATY 66
Query: 410 QASVEGFV------------EHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDD 553
Q S+ GF E G+ KE+ ++RAV LA A
Sbjct: 67 QISINGFAATKAPRSGTVDEEREGIEKEEIPRFLSRAVVLAANAAG----------TEGK 116
Query: 554 IPLIVGSVGPYGAHLHDGSEYDGSY-ADTTSIETMREWHRPRIQALVEAG---VDLLALE 721
+ L S+GPYGA + +EY G Y + ++ + +WH+ R+ + V+ +A E
Sbjct: 117 VAL---SLGPYGATMIPSTEYSGRYDPEHQHVQALGKWHKERLDLFKDVDPNQVNYIAFE 173
Query: 722 TIPCQEEAETLCDLL------REFPGTKAWLAFSC-KDDQSIAHGESFQKVAKKCWELNP 880
T+P +E + +LL G W++ DD + G + ++V K
Sbjct: 174 TVPRLDEIVAIRNLLSADNIPTSLRGRPVWISSPYPNDDGKLPDGSTVEEVVKAVLTHRE 233
Query: 881 --DQLVAVGVNCCARSFVSNLMKGXND 955
+ +G+NC + +L+K D
Sbjct: 234 GLETPWGIGINCTKVEKLDSLVKRYED 260
>UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1;
Pseudoalteromonas atlantica T6c|Rep: Homocysteine
S-methyltransferase - Pseudoalteromonas atlantica
(strain T6c / BAA-1087)
Length = 304
Score = 66.9 bits (156), Expect = 1e-09
Identities = 68/243 (27%), Positives = 106/243 (43%), Gaps = 2/243 (0%)
Frame = +2
Query: 209 SSENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGAD 388
+S + I +LDGG +L D P+WSA + P V + H +F+ +GA
Sbjct: 3 ASTSASKSTITILDGGMGQELLRRSSR--DVTPMWSADIMLNEPELVRDLHREFINSGAR 60
Query: 389 LIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIV 568
+I NTY A+ + EQ L A++ A++A L Q DD+ +I
Sbjct: 61 VITLNTYTATPQRLKRENQF--EQFVHLHDAAMRAAQEAIAL--------TQRDDV-MIA 109
Query: 569 GSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAE 748
GS+ P A H E S+ D S+ + R+ + AL G D+ ET+ EA+
Sbjct: 110 GSLPPLVASYH--PEVSLSFED--SLVSYRQ-----LVALQSLGSDIFICETMSSICEAQ 160
Query: 749 TLCDLLREFPGTKAWLAFSCKDDQ--SIAHGESFQKVAKKCWELNPDQLVAVGVNCCARS 922
C +E G W+AF+ D + + GE + L+PD A+ +NC
Sbjct: 161 AACTAAKE-SGKPVWVAFTVSDTEPDQLRSGELLKDALDALKALSPD---AIMLNCSLPE 216
Query: 923 FVS 931
+S
Sbjct: 217 AIS 219
>UniRef50_Q966F6 Cluster: Putative uncharacterized protein T13G4.4;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T13G4.4 - Caenorhabditis elegans
Length = 334
Score = 65.3 bits (152), Expect = 3e-09
Identities = 42/136 (30%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = +2
Query: 569 GSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVE--AGVDLLALETIPCQEE 742
GSVG HD SEY G+Y D + + + I L + + L ETIP +E
Sbjct: 169 GSVGTLATMYHDLSEYTGAYMDQSEAKKTAYDYFKIILTLFHNRSSIRKLIFETIPSADE 228
Query: 743 AETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARS 922
D+L+EFP +A ++F+ K+ + HGE VA++ + +P Q++ +G+NC +
Sbjct: 229 GSVALDVLQEFPEFEAVISFTFKEHGCLRHGEKITSVAQQ-MKQSP-QVLGIGINC---T 283
Query: 923 FVSNLMKGXNDDRPQA 970
+N++ N+ +P A
Sbjct: 284 DPNNVLPALNELQPFA 299
>UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Rep:
AFR410Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 370
Score = 64.5 bits (150), Expect = 5e-09
Identities = 67/239 (28%), Positives = 103/239 (43%), Gaps = 13/239 (5%)
Frame = +2
Query: 233 HIVVLDGGFSTQLSCHVGHVIDGDPLWS-ARFIHTHP---NEVVNTHLDFLRAGADLIIT 400
+++V+DGG +L V PLWS A F+ + + + +F AG+ I T
Sbjct: 58 NVLVMDGGMGVELERRGMDV--KSPLWSTAPFLRGDRAALDTIRGLYREFRAAGSRGIST 115
Query: 401 NTYQASVEGFVEHLG-VTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSV 577
TYQAS V++ G V+ YE Q+ ++ RDY I+GSV
Sbjct: 116 LTYQASFHSMVKYSGSVSSRADYEKFLE--QVVDFTYRECVDPARDY--------IIGSV 165
Query: 578 GPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQAL-VEAGVDLLALETIPCQEEAETL 754
GPY A L +G+EY G Y T + P++ + +D +A ET+P E +
Sbjct: 166 GPYAAFLCNGAEYTGDYGFETI--NFFNYFEPQVSKFATDPRIDAIAFETVP--NVVELM 221
Query: 755 CDLLREF----PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELN---PDQLVAVGVNC 910
L EF +++ S KD+ + G V + E P L+ G+NC
Sbjct: 222 AMLQPEFHALLKNKPFYISISAKDEHVLRDGTPLAVVGQLIRERMDDLPPNLLCFGLNC 280
>UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 374
Score = 63.7 bits (148), Expect = 9e-09
Identities = 57/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVID-GDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 412
I +LDGG T L G V PLWS+ + + + +F AGAD+++T TYQ
Sbjct: 4 IKILDGGLGTTLEDRFGVVFTHAKPLWSSDLLVSDQETLQACQREFAAAGADVLLTATYQ 63
Query: 413 ASVEGFV-----EHL-GVTKEQ--------GYELIARAVQLAKQARTLYLEEYRDYVQ-- 544
SVE F EH G+ E+ +A A A R+
Sbjct: 64 VSVEAFARTKTPEHPDGIAPSSAMLPYLRGAVEIAEKAAAAAAAAAAAAAAAPRNETSAP 123
Query: 545 NDDIPLIVGSVGPYGAHLHDGSEYDGSY-ADTTSIETMREWHRPRIQALVEAGVDL---- 709
+ + + GPYGA + G EY G+Y A ++ + + WH R+ AG D+
Sbjct: 124 SPQPAELALACGPYGAAMTPGQEYTGAYDAAHSTPDALSRWHLDRLALYAAAGEDVPGRC 183
Query: 710 --LALETIPCQEEAETLCDLL 766
+A ET+P E + D +
Sbjct: 184 AYVAFETVPNLAEVWAVRDAI 204
>UniRef50_Q4WFR2 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Trichocomaceae|Rep: Homocysteine
S-methyltransferase, putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 313
Score = 60.9 bits (141), Expect = 6e-08
Identities = 51/195 (26%), Positives = 96/195 (49%), Gaps = 2/195 (1%)
Frame = +2
Query: 380 GADLII-TNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI 556
G +++ T T++ + + + +G++ ++ EL AV+LAK+AR R ++I
Sbjct: 63 GTGIVLDTRTWRGATP-WAQPMGLSADKLLELNRAAVRLAKEARN------RAVGGENNI 115
Query: 557 PLIV-GSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPC 733
P+++ G++GP D SE ++E RE +R +++ L +AGVD+LA+ T+
Sbjct: 116 PVVISGTMGPLRDAYVDTSEL-------ITLEDAREGYREQVEVLADAGVDMLAIMTVTN 168
Query: 734 QEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCC 913
EA + +L +E ++FS + D + G S + E +V GVNC
Sbjct: 169 LNEAIAVVELAKEV-RLPVVVSFSIESDGRLLGGRSLGSAIRTVDEKTGGSVVYYGVNCA 227
Query: 914 ARSFVSNLMKGXNDD 958
+S ++ +D
Sbjct: 228 HPVRISAALRDVPED 242
>UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1;
Marinobacter sp. ELB17|Rep: Putative uncharacterized
protein - Marinobacter sp. ELB17
Length = 303
Score = 59.3 bits (137), Expect = 2e-07
Identities = 65/240 (27%), Positives = 101/240 (42%), Gaps = 5/240 (2%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+V+LDGG ++ +V LWS +H P+ V H DF+RAGA + NTY A
Sbjct: 4 VVLLDGGLGQEIYRRAANV--SSALWSVAVMHEQPDVVTAVHSDFIRAGAKTLSLNTYAA 61
Query: 416 SV-----EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVG 580
+ G +E L + +EL+ +AV+ I G +
Sbjct: 62 TPSRLLRHGQLEQLAAIHQNAFELLGQAVKATGACVD-----------------IAGCLP 104
Query: 581 PYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCD 760
P GS Y G A S E +R+ + ++ +A D+L +ET+ EA C
Sbjct: 105 PLA-----GS-YQGQPA--RSFEDLRDEYSVLVKQ--QAVADVLLIETMTNTLEACAACA 154
Query: 761 LLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLM 940
E G +AF + D + GE+ +A+ ++P AV +NCC +S M
Sbjct: 155 AASEL-GKPYGVAFRLEADGKLMSGET---LAEAVAAVSPYSPTAVMLNCCDPELISAAM 210
>UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase,
putative; n=2; Trypanosoma cruzi|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma cruzi
Length = 410
Score = 57.2 bits (132), Expect = 8e-07
Identities = 56/201 (27%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+++ DG T L +WS+ + + + V H ++ AG D+++T TYQ
Sbjct: 9 VLIKDGAMGTLLESWDVDYAKAGSMWSSSVLLSEMDLVKRAHRAYIDAGCDVLLTCTYQM 68
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLA------------------KQARTLYLEEYRDYV 541
EG +K EL+ RAVQ A K+ RT ++ +R +
Sbjct: 69 HEEG----CAASKVTMCELVDRAVQAARHTMPQRKQKGLTEESTAKERRTGGIDVFRYAL 124
Query: 542 QN------DDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQA-LVEAG 700
+ + + L+ GS+GPYG+ L G EY G Y+ ++ + +H R++A L G
Sbjct: 125 SSIKDNGQERVVLLAGSLGPYGSSLPGGQEYLGEYSIHEAV--INAFHARRLEAFLCNVG 182
Query: 701 ------VDLLALETIPCQEEA 745
VD L LET P +EA
Sbjct: 183 EKHAFKVDFLLLETFPRLDEA 203
>UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Methylenetetrahydrofolate reductase - Herpetosiphon
aurantiacus ATCC 23779
Length = 617
Score = 56.8 bits (131), Expect = 1e-06
Identities = 64/228 (28%), Positives = 97/228 (42%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
++ DG TQL G ID D + A + T P+ V H ++ AGAD+I TNTY A+
Sbjct: 14 LLCDGAMGTQL---YGRGIDFDECFDALNL-TQPDVVREIHQSYIEAGADIIETNTYGAN 69
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
+E G+ ++ ++ R ++LA++AR + LI G+VGP G L
Sbjct: 70 -RFKLEPFGLA-DKVRQINHRGMKLAREAREI----------AGTNTLIAGAVGPLGVLL 117
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFP 778
Y T + E +I L+E G DLL ET E ++
Sbjct: 118 Q-------PYGPLTE-QAAHEAFAEQIGTLLEQGADLLMFETFSDLREMLIAVKAAKQVG 169
Query: 779 GTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARS 922
+ +D G + ++V +K EL + VGVNC S
Sbjct: 170 DLPIVAQMTFAEDGRTVLGNTPEEVVRKLVELG---VAVVGVNCSVGS 214
>UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9;
Saccharomycetaceae|Rep: Homocysteine S-methyltransferase
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 325
Score = 55.2 bits (127), Expect = 3e-06
Identities = 67/287 (23%), Positives = 126/287 (43%), Gaps = 18/287 (6%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSA-RFI-------HTHPNEVVNTHL--DFLRAGA 385
++VLDGG T+L V +P+WS FI + N + + DFL AGA
Sbjct: 17 VLVLDGGQGTELENRGIKV--ANPVWSTIPFISESFWSDESSANRKIVKEMFNDFLNAGA 74
Query: 386 DLIITNTYQASVEGFVEHLGV-TKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPL 562
++++T TYQ S + E+ + T + L+ R V + R+ + D
Sbjct: 75 EILMTTTYQTSYKSVSENTPIRTLSEYNNLLNRIVDFS-----------RNCIGED--KY 121
Query: 563 IVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAG-VDLLALETIPCQE 739
++G +GP+GAH+ E+ G Y ++ +P+++ + +DL+ ETIP
Sbjct: 122 LIGCIGPWGAHI--CREFTGDYGAEPENIDFYQYFKPQLENFNKNDKLDLIGFETIPNIH 179
Query: 740 EAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWEL----NPDQLVAVGVN 907
E + + ++ S + + G + +++A+ +L NP+ +G+N
Sbjct: 180 ELKAILSWDESILSRPFYIGLSVHEHGVLRDGTTMEEIAQVIKDLGDKINPN-FSFLGIN 238
Query: 908 CCARSFVSNLMKGXNDDRPQAPXRLWLP*FGRKYNPQ--IGXINRDK 1042
C + + ++++ + P L P G Y+ + I N DK
Sbjct: 239 CVSFNQSPDILESLHQALPNMAL-LAYPNSGEVYDTEKKIWLPNSDK 284
>UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25;
Cyanobacteria|Rep: Methionine synthase - Synechococcus
sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 1224
Score = 54.8 bits (126), Expect = 4e-06
Identities = 54/194 (27%), Positives = 84/194 (43%), Gaps = 4/194 (2%)
Frame = +2
Query: 197 MTPPSSENTEAPHIVVLDGGFSTQLSCHVGHVID-GDPLWSA---RFIHTHPNEVVNTHL 364
MT P ++ + ++V DG + L D G P + T P V H
Sbjct: 1 MTHPFLQHLQE-RVIVFDGAMGSSLQAQNLTAADFGGPELEGCNEMLVLTKPEAVERVHR 59
Query: 365 DFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQ 544
FL GAD++ TNT+ A+ E+ G+ E+ YEL A +LAK+ ++
Sbjct: 60 GFLEVGADVVETNTFGATSIVLAEY-GI-PEKAYELNVAAARLAKRVAA-------EFAT 110
Query: 545 NDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALET 724
+ + GS+GP G S + MR + ++Q LV+ G DLL +ET
Sbjct: 111 PEKPRFVAGSIGPTTKLPTLGH---------ISFDEMRAAYEEQVQGLVDGGADLLIIET 161
Query: 725 IPCQEEAETLCDLL 766
CQ+ +T L+
Sbjct: 162 --CQDILQTKAALV 173
>UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Rep:
Mlr1281 protein - Rhizobium loti (Mesorhizobium loti)
Length = 301
Score = 54.4 bits (125), Expect = 5e-06
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 2/229 (0%)
Frame = +2
Query: 233 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 412
++++ DGG +L + PLWSAR + P+ V + H +F+RAGA +I NTY
Sbjct: 3 NVILTDGGMGQELVRRSKS--EPTPLWSARVLIDEPDLVRDLHAEFIRAGARVITINTYS 60
Query: 413 ASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGA 592
A+ E ++ L R ++LA+QA +E + I G + P
Sbjct: 61 ATPERLARE--GAEDLFKPLQKRGIELARQA----CDEAGE-------AAIAGCLSP--- 104
Query: 593 HLHDGSEYDGSYAD--TTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLL 766
GSYA T S + + +R RI A GVDL ET+ +EA
Sbjct: 105 -------LFGSYAPALTISYQETLDIYR-RIVAEQADGVDLFLCETMASSDEARAAVTAA 156
Query: 767 REFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCC 913
E G W++++ D S + +A L+ + A +NCC
Sbjct: 157 SE-SGKPVWVSWTLA-DHGTPRLRSGETIAAAASALDGLPIAARLLNCC 203
>UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family
protein; n=1; Alteromonas macleodii 'Deep ecotype'|Rep:
Homocysteine S-methyltransferase family protein -
Alteromonas macleodii 'Deep ecotype'
Length = 305
Score = 54.4 bits (125), Expect = 5e-06
Identities = 56/193 (29%), Positives = 87/193 (45%), Gaps = 3/193 (1%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
I +LDGG +L +G P WSA + P V + H FL AGA +I TNTY
Sbjct: 8 IQILDGGMGRELK-KIGAPFR-QPEWSALALMQSPELVSDVHTHFLNAGATVITTNTY-- 63
Query: 416 SVEGFVEHLG--VTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP-Y 586
++ F H+G EQ ++L A +LA+ A ++ + + G + P +
Sbjct: 64 ALVPF--HIGEQTFNEQAFKLAETAAKLARDAVNAQQDKQEGNLS------VAGCIPPAF 115
Query: 587 GAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLL 766
G++ D +D S + E P I+A +D+ +ET EEAE + L+
Sbjct: 116 GSYRPD--LFDAS--------RVSEILMPLIEAQAPY-IDVWLIETASSIEEAEAVVSLI 164
Query: 767 REFPGTKAWLAFS 805
+ WL+FS
Sbjct: 165 KTLSSRPIWLSFS 177
>UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2;
Gammaproteobacteria|Rep: Homocysteine
S-methyltransferase - Psychromonas ingrahamii (strain
37)
Length = 310
Score = 54.4 bits (125), Expect = 5e-06
Identities = 59/199 (29%), Positives = 91/199 (45%), Gaps = 6/199 (3%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
++LDGG +L +G P WSA+ + P+ + H F+ AGA++I TNTY +
Sbjct: 17 IILDGGMGRELK-RIGAPFQ-QPEWSAQALIESPHFISEVHKSFIEAGAEVITTNTY--A 72
Query: 419 VEGFVEHLGVTK--EQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGA 592
+ F H+G + EQG +LI A +LA R+ V+ + L+ G + P
Sbjct: 73 LVPF--HIGEKRFNEQGADLIKLAARLA-----------RECVKENSAVLVAGCIPP--- 116
Query: 593 HLHDGSEYDGSY-ADTTSIETMREWHRPRIQALV---EAGVDLLALETIPCQEEAETLCD 760
GSY D S+E +P ++ L+ EA VD+ ETI EA +
Sbjct: 117 -------VLGSYRPDLFSVEKA----KPVLELLIKNQEADVDIWLAETISSIAEA-AMIK 164
Query: 761 LLREFPGTKAWLAFSCKDD 817
W+AF+ KD+
Sbjct: 165 ARTVVTNKPTWIAFTIKDE 183
>UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine
methyltransferase, truncation; n=8;
Desulfuromonadales|Rep:
5-methyltetrahydrofolate-homocysteine methyltransferase,
truncation - Geobacter sulfurreducens
Length = 804
Score = 53.2 bits (122), Expect = 1e-05
Identities = 53/182 (29%), Positives = 79/182 (43%)
Frame = +2
Query: 227 APHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNT 406
A ++VLDG T L G P T P V H ++L AGAD+I+TNT
Sbjct: 10 AERVLVLDGAMGTMLQ-ERGLRPGQSP---EELNLTLPEVVAGVHREYLDAGADIIVTNT 65
Query: 407 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 586
+ S +EH G+ +++ E+ ARAV +A++ D + S+GP
Sbjct: 66 FGGS-RAKLEHYGL-QDRVAEINARAVAIAREVC-------------GDRAYVAASIGPT 110
Query: 587 GAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLL 766
G + + S + M R + QAL+ AG DL+ LET +E +
Sbjct: 111 GQFVEPVGD--------VSFDEMAAIFREQAQALINAGADLITLETFLDIKEIRAAVIAI 162
Query: 767 RE 772
RE
Sbjct: 163 RE 164
>UniRef50_A4XIN5 Cluster: Methylenetetrahydrofolate reductase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Methylenetetrahydrofolate reductase -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 604
Score = 52.8 bits (121), Expect = 2e-05
Identities = 59/226 (26%), Positives = 101/226 (44%), Gaps = 1/226 (0%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
IV+ DG T+L + G+ D W+ ++P+ V + H D++ AG+ I TNT+ A
Sbjct: 13 IVLFDGAMGTEL-LNRGYNKDFPLEWANI---SNPDLVKSIHSDYILAGSQCIETNTFGA 68
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
+ E + G + Q ++ AV++AK+ ++GSVGP G
Sbjct: 69 N-ECRLNLYGF-EGQVEKINRNAVKIAKEVA-------------GQTAYVIGSVGPLGKP 113
Query: 596 LHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREF 775
+ G E D A +E ++ ++ L++ GVD + ET E + L+E
Sbjct: 114 VGSGFEIDDKRA--------KEVYKKQLYFLLDEGVDAILFETAASTHEVLIAIEALKEL 165
Query: 776 PGTKAWLA-FSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
++ FS D + +GE KV + ++ D VG+NC
Sbjct: 166 DSNFPYIVQFSFTRDLTTIYGEDIYKVIEFLKGIDAD---VVGLNC 208
>UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5;
Alphaproteobacteria|Rep: Homocysteine
S-methyltransferase - Dinoroseobacter shibae DFL 12
Length = 350
Score = 50.8 bits (116), Expect = 7e-05
Identities = 67/245 (27%), Positives = 98/245 (40%), Gaps = 3/245 (1%)
Frame = +2
Query: 215 ENTEAP-HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADL 391
EN P I +LDGG +L G PLWS + P+ V H DF AGA++
Sbjct: 37 ENRNRPMDITLLDGGLGQELVRRAGRAT---PLWSMEALLNAPDLVRAVHDDFFAAGAEV 93
Query: 392 IITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVG 571
TNTY + +Q L RA +A A RD L+ G
Sbjct: 94 ATTNTYAVLPDRLAAF--DMADQLAPLTERACGIAAAA--------RDAAGGG---LVAG 140
Query: 572 SVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAET 751
++GP G + D + + E E R+QA + VD+L LET+ ++A
Sbjct: 141 ALGPLGF----SYQPDKAPPPEQAAEIYAE--VARLQARI---VDVLVLETMSSVDQARG 191
Query: 752 LCDLLREFPGTKAWLAFSC--KDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSF 925
+ + G WLA S D + GE ++ +PD+++ +NC
Sbjct: 192 GM-MGAQVAGKPVWLALSVDDADGTKLRSGEPLAAISPVLETFSPDRVL---INCARPEA 247
Query: 926 VSNLM 940
VS M
Sbjct: 248 VSQAM 252
>UniRef50_P74718 Cluster: Slr1189 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Slr1189 protein - Synechocystis sp.
(strain PCC 6803)
Length = 351
Score = 50.0 bits (114), Expect = 1e-04
Identities = 64/242 (26%), Positives = 103/242 (42%), Gaps = 12/242 (4%)
Frame = +2
Query: 221 TEAPH----IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHP--NEVVNTHLD-FLRA 379
T PH I +LDGG T++ + G + P ++A + + P E + + FL
Sbjct: 40 TNLPHQCEQIFLLDGGLETEMIFNRGFDL---PAFAAHTLLSDPLGREALKNYFHGFLDL 96
Query: 380 GAD-----LIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQ 544
+ LI T++A F E LGV+ E+ + RAV+ A+ + Y+ E +
Sbjct: 97 AKEKQFGFLIDAPTWRAQ-PFFAEELGVSLEEIRQANFRAVEFARALKQAYVNEIQPL-- 153
Query: 545 NDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALET 724
LI G +GP G Y G + ++ E + +HR +I L EAGVDLL T
Sbjct: 154 -----LINGLIGPCG------DAYGGEHF--SNAEAAQVYHRQQISWLAEAGVDLLGAFT 200
Query: 725 IPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGV 904
+ EA + +EF ++F+ + D + G + + E V
Sbjct: 201 LTSVNEAIGIVRASQEF-SLPVSISFTVETDGRLPTGTALSEAIAIVDEATNQGAAYFMV 259
Query: 905 NC 910
NC
Sbjct: 260 NC 261
>UniRef50_Q93A68 Cluster: Methylenetetrahydrofolate reductase; n=2;
Bacteria|Rep: Methylenetetrahydrofolate reductase -
uncultured bacterium
Length = 612
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/199 (30%), Positives = 86/199 (43%), Gaps = 7/199 (3%)
Frame = +2
Query: 335 HPNEVVNTHLDFLRAGADLIITNTYQAS-VEGF-VEHLGVTKEQGYELIARAVQLAKQAR 508
+P+ V H ++ AGA LI TNTY A+ V F + G Y L+ + + R
Sbjct: 28 YPDTVRALHREYYEAGARLIETNTYTANRVRLFNLPERGSEAPPTYSLLEQFGSPEELVR 87
Query: 509 TLYLEEYR---DYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRI 679
+ E R + V D L+ GSVGP G L E T ++ R ++
Sbjct: 88 RINQEAVRLAREAVGAD--ALVFGSVGPVGKPLEPIGE--------TRLDEAEGAFREQM 137
Query: 680 QALVEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFS--CKDDQSIAHGESFQKV 853
QAL+EAGVD L LET E E + RE +A +D +++ G ++
Sbjct: 138 QALLEAGVDGLILETFIDPRELELAIRVARELAPDLPLIASKGFVEDGETLMEGLP-ERF 196
Query: 854 AKKCWELNPDQLVAVGVNC 910
A L D AVG NC
Sbjct: 197 AHTVSALGVD---AVGANC 212
>UniRef50_A5UPF4 Cluster: Methionine synthase; n=4;
Chloroflexaceae|Rep: Methionine synthase - Roseiflexus
sp. RS-1
Length = 1254
Score = 50.0 bits (114), Expect = 1e-04
Identities = 48/167 (28%), Positives = 79/167 (47%), Gaps = 4/167 (2%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVID--GDPLWSAR--FIHTHPNEVVNTHLDFLRAGADLIITN 403
+++ DG T + D G+ + AR + T P+ + H FL AGAD++ T
Sbjct: 58 VLIYDGAMGTSIDTFHLTAADYGGENTFGARDYLVMTRPDVIEQIHTSFLEAGADVLETC 117
Query: 404 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 583
T+Q S +E G+ +Q + + A +LA++ + E RD + GS+GP
Sbjct: 118 TFQ-STRIRLEEWGLA-DQTHAINVAAARLARRVADAF--EARDGRPR----YVAGSMGP 169
Query: 584 YGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALET 724
G S D S +D T + + + + AL+E GVD+L +ET
Sbjct: 170 TGKL---PSSDDPSLSDIT-FDQLSDIFYEQAVALIEGGVDVLLVET 212
>UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family
protein; n=6; Vibrionales|Rep: Homocysteine
S-methyltransferase family protein - Vibrio splendidus
12B01
Length = 299
Score = 50.0 bits (114), Expect = 1e-04
Identities = 33/90 (36%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+ +LDGG +L + PLWSA+ + P V H +F+ AGA+++ITN+Y A
Sbjct: 4 LTILDGGMGRELK-EIDAPFS-QPLWSAQALIEAPEFVSQAHQNFVDAGAEILITNSY-A 60
Query: 416 SVEGFVEHLG--VTKEQGYELIARAVQLAK 499
V HLG + +++G+EL A++ +LAK
Sbjct: 61 CVP---FHLGEELFEQRGFELAAQSGELAK 87
>UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Trypanosoma brucei|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma brucei
Length = 433
Score = 50.0 bits (114), Expect = 1e-04
Identities = 59/206 (28%), Positives = 86/206 (41%), Gaps = 35/206 (16%)
Frame = +2
Query: 233 HIVVLDGGFSTQLS-CHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 409
H +DG T + C + G +WS + T V H +L GAD+I+TNTY
Sbjct: 23 HFFTMDGAVGTLVERCGLDPSKMGS-MWSTSALITDEEIVRYVHKSYLDVGADVILTNTY 81
Query: 410 QASVEGFVEHLGVTKEQ----GYELIARAVQLAKQARTLYLEEYRDYVQN---------- 547
Q G + GVT + ++ + + A T + + +V N
Sbjct: 82 QMHAAGCAQ-AGVTMNEVVNTAVRVLCDGITPERAAATKEAKVWAQHVMNNKRSEFVNVF 140
Query: 548 --------DD---IPLIV-GSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
DD P++V GS+G YGA L + EY G Y I +R+++ R A V
Sbjct: 141 APLFYGPRDDASKCPVLVGGSLGSYGASLGNAQEYRGEYEVNEDI--IRDYYVGRFMAFV 198
Query: 692 ------EA--GVDLLALETIPCQEEA 745
EA VD + +ETIP EA
Sbjct: 199 NHVDEKEAHLKVDFIMIETIPLLNEA 224
>UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 1231
Score = 48.8 bits (111), Expect = 3e-04
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 1/132 (0%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + + H +L AGAD+ TNT+ A+ +E G+ + Q + A +LA++
Sbjct: 57 TRPDVIKSIHRQYLDAGADIFATNTFNANAIS-MEDYGM-QGQVRNINLAAGKLAREVAD 114
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEY-DGSYADTTSIETMREWHRPRIQAL 688
+++E+ D + GSVGP + D +Y T ++ + ++ ++ AL
Sbjct: 115 GFMKEHPDRT-----IFVAGSVGPTNKTASMSPDVSDPAYRAVTYLD-LYSAYKEQVDAL 168
Query: 689 VEAGVDLLALET 724
V+ GVD++ ET
Sbjct: 169 VDGGVDIVLFET 180
>UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Homocysteine S-methyltransferase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 411
Score = 48.8 bits (111), Expect = 3e-04
Identities = 49/171 (28%), Positives = 78/171 (45%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
++V DG TQL + + LWS T P + H D+ AG+D + TNT+ A
Sbjct: 10 VLVFDGAMGTQLIQNGLKENECPDLWSV----TRPEVIAKIHRDYFEAGSDCVETNTFGA 65
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
+ E ++ G+ E ++ A+ LAK +EY YV SVGP G
Sbjct: 66 NREKLKKY-GLENEV-EKINKAAILLAKDV----AKEYGGYVGL--------SVGPTGRL 111
Query: 596 LHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAE 748
+ + D A++ E +I A +EAG D +++ET+ +EA+
Sbjct: 112 MRPSGDLDFDEAESVFYE--------QILAGIEAGADFISIETMSDIKEAK 154
>UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=1; Salinibacter ruber DSM 13855|Rep:
Vitamin B12-dependent methionine synthase family protein
- Salinibacter ruber (strain DSM 13855)
Length = 320
Score = 48.4 bits (110), Expect = 4e-04
Identities = 41/115 (35%), Positives = 55/115 (47%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
V+LDGG +L G LWSA + P+ V H ++LRAGAD+I TNTY
Sbjct: 13 VLLDGGLGQEL-IRRGMPSTEPSLWSANALTEAPDLVQEVHEEYLRAGADVITTNTYATP 71
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 583
E E G+ + L A +LA++AR RD + +P I GS P
Sbjct: 72 PERLSE-AGL-DGRAEALNREAGRLAERARAAV---GRDALIAGSLPPIRGSYRP 121
>UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1;
Desulfotomaculum reducens MI-1|Rep: Homocysteine
S-methyltransferase - Desulfotomaculum reducens MI-1
Length = 800
Score = 48.4 bits (110), Expect = 4e-04
Identities = 44/132 (33%), Positives = 60/132 (45%), Gaps = 1/132 (0%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVE-HLGVTKEQGYELIARAVQLAKQAR 508
+HP V H +L AGAD+I TNT+ A + HLG +Q E+ AV+LAK+
Sbjct: 39 SHPEAVKEIHKLYLEAGADIITTNTFGAIQLKLADYHLG---DQVKEINQAAVKLAKEVA 95
Query: 509 TLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQAL 688
Y ++ GSVGP G L T + E + + A+
Sbjct: 96 QPYGA------------MVAGSVGPLGKFLQP--------LGTMTFEEAYQQFYEQCAAM 135
Query: 689 VEAGVDLLALET 724
VEAGVDL+ ET
Sbjct: 136 VEAGVDLILFET 147
>UniRef50_Q2LQ11 Cluster: Methylenetetrahydrofolate reductase; n=1;
Syntrophus aciditrophicus SB|Rep:
Methylenetetrahydrofolate reductase - Syntrophus
aciditrophicus (strain SB)
Length = 618
Score = 48.0 bits (109), Expect = 5e-04
Identities = 56/195 (28%), Positives = 88/195 (45%), Gaps = 2/195 (1%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQAR- 508
T P ++ H + +AGA ++ TN++ A+ + G+ E+ ++ A +LA+QA
Sbjct: 43 TEPGLILGIHEQYAQAGAQVLETNSFGAN-RIKLRAYGLA-EKVADINRAAARLARQAAG 100
Query: 509 -TLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQA 685
TLY + GSVGP G G D +E R +++A
Sbjct: 101 TTLY---------------VAGSVGPC---TQGGQVITGR--DMAEVEAA---FREQMEA 137
Query: 686 LVEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKC 865
L E GVDLL LET +E + + RE G +F+ DD A G +K+A
Sbjct: 138 LTEEGVDLLLLETFSDLKELQLAARVARE-RGVPVLASFAVDDDGETAAGTPAEKMA-AA 195
Query: 866 WELNPDQLVAVGVNC 910
E +P + +G+NC
Sbjct: 196 LEKDP-HVDVIGLNC 209
>UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium
nucleatum|Rep: Methionine synthase - Fusobacterium
nucleatum subsp. polymorphum ATCC 10953
Length = 1082
Score = 47.6 bits (108), Expect = 6e-04
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFI--HTHPNEVVNTHLDFLRAGADLIITNTY 409
I+VLDG T L + D + I T P+ + H ++ AGAD+I TN++
Sbjct: 12 ILVLDGAMGTVLQKYELTPEDFNGAKGCYEILNETRPDIIFEVHKKYIEAGADIIETNSF 71
Query: 410 QASVEGFVE-HLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 586
+ + HL +++ Y+L ++ ++A+ A ++E V + GS+GP
Sbjct: 72 NCNAISLKDYHL---EDKVYDLAKKSAEIARDA----VKESGKKV------YVFGSIGPT 118
Query: 587 GAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETI 727
L D Y S + M+E + ++ L++ GVD + LETI
Sbjct: 119 NKSL-SFPVGDVPYKRAVSFDEMKEVIKVQVAGLIDGGVDGILLETI 164
>UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=8; Cyanobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Prochlorococcus marinus
Length = 1182
Score = 46.8 bits (106), Expect = 0.001
Identities = 48/178 (26%), Positives = 80/178 (44%), Gaps = 4/178 (2%)
Frame = +2
Query: 218 NTEAPHIVVLDGGFSTQL-SCHVGHVIDGDPLWSA---RFIHTHPNEVVNTHLDFLRAGA 385
N+ ++V DG T L S ++ G L + T+P V N H +L G
Sbjct: 9 NSSKSSVLVFDGAMGTSLQSLNLTADDFGGTLLEGCNENLVLTNPQAVRNVHRSYLEVGC 68
Query: 386 DLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLI 565
D+I TNT+ A+ E+ +++ YE+ A +LAK +++ +D +
Sbjct: 69 DVIETNTFGATSIVLEEY--NLQDKTYEINLEAARLAKGI-------VKEFSTDDKPRFV 119
Query: 566 VGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQE 739
GSVGP G S + + ++ +I+AL++ VDL+ LET CQ+
Sbjct: 120 AGSVGPTTKLPTLGH---------ISFDKLSSSYQEQIEALIDGEVDLILLET--CQD 166
>UniRef50_A1GFF8 Cluster: Homocysteine S-methyltransferase; n=2;
Micromonosporaceae|Rep: Homocysteine S-methyltransferase
- Salinispora arenicola CNS205
Length = 307
Score = 46.4 bits (105), Expect = 0.001
Identities = 56/228 (24%), Positives = 91/228 (39%), Gaps = 4/228 (1%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNE--VVNTHLDFLRAGADLIITNTYQ 412
++LDGG T+L G + P W+A + + H +++ AGAD+I +T++
Sbjct: 10 LILDGGLGTELQRR-GRSVTA-PWWTAHCLRDADGRRLIAQIHAEYVTAGADVITADTFR 67
Query: 413 ASVEGFVEHLGVTKEQ-GYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY- 586
+ G+ +L+ AV LA++A D V+ L+ GSV P
Sbjct: 68 TTPRA-AHRAGIAGHTVAADLVRTAVALAREAA--------DTVRRR--VLVAGSVAPVE 116
Query: 587 GAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLL 766
+ D DG +R H + L VDL+ +ET+ EA +
Sbjct: 117 DCYRPDLVPNDG---------VLRREHAWLAEQLARTSVDLVLVETMNTAREAVAATRAV 167
Query: 767 REFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
G AW++F C +D + G A D ++ VNC
Sbjct: 168 CA-EGLPAWVSFVCTNDARLLSGTDVVAAAAAVRAAGADMVL---VNC 211
>UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1;
Vibrio harveyi ATCC BAA-1116|Rep: Putative
uncharacterized protein - Vibrio harveyi ATCC BAA-1116
Length = 301
Score = 45.2 bits (102), Expect = 0.003
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+ +LDGG +L PLWSA+ + P V H +F++AGA++II N+Y A
Sbjct: 4 LTILDGGMGRELKRMSAPF--SQPLWSAQALIESPEFVYQAHDNFIQAGAEIIIANSY-A 60
Query: 416 SVEGFVEHLG--VTKEQGYELIARAVQLAKQ 502
V HLG + +QG +L A ++A++
Sbjct: 61 CVP---FHLGQELYDQQGSKLARFAAKIARE 88
>UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associated
KRAB repressor, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to RB-associated KRAB
repressor, partial - Ornithorhynchus anatinus
Length = 395
Score = 44.8 bits (101), Expect = 0.004
Identities = 36/148 (24%), Positives = 67/148 (45%)
Frame = +2
Query: 284 GHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQG 463
G + GDP + NTH D+L AGAD+I TNT+ + ++ G+ +
Sbjct: 79 GRSLPGDPAPPTEEMKYDXXXXNNTH-DYLLAGADIIETNTFSGTRVAQADY-GL-EHLA 135
Query: 464 YELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTS 643
YEL + ++A++A Q + G++GP L + +
Sbjct: 136 YELNRTSAEVARRAADDVA------AQTGTKRFVAGALGPTNKTLSVSPSVERPDFRNIT 189
Query: 644 IETMREWHRPRIQALVEAGVDLLALETI 727
+ + E +R + + L++ GVD++ +ET+
Sbjct: 190 FDELAEAYREQARGLLDGGVDIVLVETV 217
>UniRef50_Q748M7 Cluster: Methylenetetrahydrofolate reductase; n=8;
Desulfuromonadales|Rep: Methylenetetrahydrofolate
reductase - Geobacter sulfurreducens
Length = 605
Score = 44.8 bits (101), Expect = 0.004
Identities = 57/193 (29%), Positives = 82/193 (42%)
Frame = +2
Query: 338 PNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 517
P+ V+ H ++L AGA +I TNT+ A+ +G+ K++ E+ R QLA++A
Sbjct: 41 PSLVLELHREYLAAGARVIETNTFGANWTRLAA-IGLEKKE-REINLRGAQLAREA---- 94
Query: 518 LEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEA 697
Q D + GSVGP G E + S +T I R + AL E
Sbjct: 95 -------AQGTD-AFVAGSVGPLVR--MKGDEQELSAQETVDI------FRRQTHALAEG 138
Query: 698 GVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELN 877
VDLL LET + RE G + ++ +A G ++VA EL
Sbjct: 139 EVDLLILETFTDLAQMRHALTAARE-TGLPVVANMAFLENGRLAGGIEVERVAV---ELT 194
Query: 878 PDQLVAVGVNCCA 916
VG NC A
Sbjct: 195 AAGACVVGANCGA 207
>UniRef50_Q1IQK2 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Acidobacteria bacterium
Ellin345|Rep: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 407
Score = 44.4 bits (100), Expect = 0.006
Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 16/166 (9%)
Frame = +2
Query: 323 FIHTHPNEVVNTHLDFLRAGADLIITNTYQAS----VEGFV----EHLGVTKEQGYELIA 478
F T P + + H FL AGAD+I TNT+ A+ E FV EH G Y+ I
Sbjct: 95 FSLTQPQMIGDIHRRFLEAGADIIETNTFGATSIVQSEFFVDDPREHGGRKDADFYQKII 154
Query: 479 RAVQLA------KQARTLYLEEYRDYVQN-DDIP-LIVGSVGPYGAHLHDGSEYDGSYAD 634
L + E+ D V N P + G++GP L + + D
Sbjct: 155 DDQFLGDLAWEINETSAQQCREWADRVANATSRPRFVAGALGPLTVSLSNSPDADDPGFR 214
Query: 635 TTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLRE 772
+ + ++ + +++AL+ GVD L +ETI A+ +RE
Sbjct: 215 VVTFDQVKIAYIQQVRALIAGGVDFLLVETIFDSLNAKAALVAIRE 260
>UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransferase
1; n=61; Eumetazoa|Rep: Betaine--homocysteine
S-methyltransferase 1 - Homo sapiens (Human)
Length = 406
Score = 44.4 bits (100), Expect = 0.006
Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E A IV+ DGGF L G+V G W+ HP V H +FLRAG++++
Sbjct: 15 ERLNAGEIVIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVM 71
Query: 395 ITNTYQASVEGFVEHLG---VTKEQGYELIARAVQLAKQ 502
T T+ AS E +E+ G + K G E+ A +A+Q
Sbjct: 72 QTFTFYAS-EDKLENRGNYVLEKISGQEVNEAACDIARQ 109
>UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Plesiocystis pacifica SIR-1|Rep:
Homocysteine S-methyltransferase, putative -
Plesiocystis pacifica SIR-1
Length = 322
Score = 43.6 bits (98), Expect = 0.010
Identities = 46/162 (28%), Positives = 74/162 (45%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
++LDG +T+L G ++ PL++AR + P+ +V H D+ AGA ++ TN++
Sbjct: 8 LLLDGALATELRRR-GFELEA-PLFAARALLEAPDLLVEIHRDYALAGAQVLSTNSFGLH 65
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
+ G+ + Q EL AR+V+L AR L + + + SV P
Sbjct: 66 A-ATLARAGMAERQA-ELAARSVELTFLARQLVRQSGSERTSF----RVAASVPPPPPSP 119
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALET 724
+G + E R R ALV+AG DL+ ET
Sbjct: 120 SEGD----------APELTRAALRSLASALVDAGADLVLFET 151
>UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:
Methionine synthase - Solibacter usitatus (strain
Ellin6076)
Length = 1185
Score = 43.2 bits (97), Expect = 0.013
Identities = 33/131 (25%), Positives = 61/131 (46%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + + H +L AGAD+I TNT+ + ++ +E+ YEL A +LA++
Sbjct: 54 TRPDVIQDIHRQYLEAGADIIETNTFGGTRIALADN--KLEERAYELNFAAAKLAREVAD 111
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
+ + + GS+GP + D + +T+ ++ + + + LV
Sbjct: 112 QFSTAAKP-------RFVAGSIGP--------TNKDLNITGSTTFPEIKAAYYEQAKGLV 156
Query: 692 EAGVDLLALET 724
E G D L +ET
Sbjct: 157 EGGADYLLIET 167
>UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 306
Score = 43.2 bits (97), Expect = 0.013
Identities = 23/61 (37%), Positives = 29/61 (47%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
I +LDGG +L PLWS + + P V N H DF AGA +I NTY
Sbjct: 5 ITLLDGGMGQEL-IRRSSAAKPHPLWSLQVMMDEPELVANVHRDFCLAGARVICLNTYSV 63
Query: 416 S 418
+
Sbjct: 64 T 64
>UniRef50_Q55786 Cluster: Methionine synthase; n=5;
Cyanobacteria|Rep: Methionine synthase - Synechocystis
sp. (strain PCC 6803)
Length = 1195
Score = 43.2 bits (97), Expect = 0.013
Identities = 37/138 (26%), Positives = 63/138 (45%)
Frame = +2
Query: 326 IHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 505
+HT P V H F AGAD++ T+T+ + E+ +Q Y L A +LAK
Sbjct: 50 VHTKPEAVATVHRAFYEAGADVVETDTFGGTPLVLAEY--DLADQSYYLNKAAAELAKAV 107
Query: 506 RTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQA 685
++ + + GS+GP G L D +++++ + +++
Sbjct: 108 AA-------EFSTPEKPRFVAGSMGP-GTKLPTLGHVD--------YDSLKDAYVVQVRG 151
Query: 686 LVEAGVDLLALETIPCQE 739
L + GVDLL +ET CQ+
Sbjct: 152 LYDGGVDLLLVET--CQD 167
>UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=21; Bacteria|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Bacillus halodurans
Length = 1146
Score = 42.7 bits (96), Expect = 0.018
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Frame = +2
Query: 197 MTPPSSENTEAPHIVVLDGGFSTQLSCH--VGHVIDGDPLWSAR--FIHTHPNEVVNTHL 364
MT E IV+LDG T L G+ T P+ V + H
Sbjct: 1 MTKSLFEQQLERKIVILDGAMGTMLQAANLTADDFGGEEYEGCNEYLNETAPHVVEDIHR 60
Query: 365 DFLRAGADLIITNTYQASVEGFVEH-LGVTKEQGYELIARAVQLAKQARTLYLEEYRDYV 541
+L AGAD+I TNT+ A+ ++ LG E EL AV++AK+ EE+
Sbjct: 61 AYLEAGADVIATNTFGATDIVLDDYDLGYKAE---ELNICAVKIAKRV----AEEF---- 109
Query: 542 QNDDIP-LIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLAL 718
D P + G++GP L S + E + E +R + L++ G D+L L
Sbjct: 110 STPDWPRFVAGAMGPTTKSL--------SVTGGATFEQLIESYRQQATGLIKGGADILLL 161
Query: 719 ET 724
ET
Sbjct: 162 ET 163
>UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella
succinogenes|Rep: S-METHYLTRANSFERASE - Wolinella
succinogenes
Length = 1120
Score = 42.7 bits (96), Expect = 0.018
Identities = 39/136 (28%), Positives = 63/136 (46%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T + +++ H +L AGAD++ +NT+ A + +E G+ + YE+ Q+AK+A
Sbjct: 48 TRGDVILSIHRSYLEAGADILKSNTFGA-LPWVLEEYGI-GGRAYEMAFAGAQIAKEACD 105
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
+ R + GS+GP G L D +TM E ++ + L
Sbjct: 106 SFAPSPR---------FVAGSLGP-GTKLPSLGHID--------YDTMFEGYKEAARGLK 147
Query: 692 EAGVDLLALETIPCQE 739
E G DL LET CQ+
Sbjct: 148 EGGADLFLLET--CQD 161
>UniRef50_Q024B4 Cluster: Homocysteine S-methyltransferase; n=1;
Solibacter usitatus Ellin6076|Rep: Homocysteine
S-methyltransferase - Solibacter usitatus (strain
Ellin6076)
Length = 304
Score = 42.7 bits (96), Expect = 0.018
Identities = 49/175 (28%), Positives = 72/175 (41%)
Frame = +2
Query: 248 DGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEG 427
DG TQL + LW+ THP V+ + AG+D I+TNT+ S
Sbjct: 17 DGAMGTQLMFAGLEQGNCGELWNL----THPERVLGIQRRYAEAGSDCILTNTFGGSRIM 72
Query: 428 FVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDG 607
H K E+ AV++A++A YV +G +GP+G +
Sbjct: 73 LNRHGSSGKV--VEINRAAVEIAREA----FGGRAGYV--------IGDIGPFGGLMQ-- 116
Query: 608 SEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLRE 772
Y D T E +R + ALV+AG D + +ET EE + + RE
Sbjct: 117 -----PYGDFTE-EDVRSAFGEQAGALVDAGADAIIIETQTSLEELQLGIEAARE 165
>UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 1178
Score = 42.7 bits (96), Expect = 0.018
Identities = 30/132 (22%), Positives = 62/132 (46%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ +++ H +L AGAD + TNT+ + ++ G+ ++ Y L + ++AK+A
Sbjct: 43 TKPDAILDIHKGYLEAGADFVETNTFSGTKIAQADY-GL-EDAAYRLNRASAEVAKRA-- 98
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
Y + G++GP L + + + + + + + + L+
Sbjct: 99 ----AYEVTASTGVEKFVAGAMGPTNRTLSISPTVECPGFRNVTFDELVDAYTEQARGLL 154
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 155 DGGVDVLLVETI 166
>UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:
Methionine synthase - Anaeromyxobacter sp. Fw109-5
Length = 1149
Score = 42.3 bits (95), Expect = 0.023
Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Frame = +2
Query: 239 VVLDGGFSTQLSCH--VGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 412
+V DG TQ+ H G + T P+ V + H + G D++ TNT+
Sbjct: 12 LVFDGAMGTQIQRHQLTAAEFGGKDGANDLLTLTRPDLVEDIHARYFAVGCDVVETNTFG 71
Query: 413 ASVEGFVEH-LGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYG 589
+S E+ LG + YE+ RA LA++A + D + GS+GP G
Sbjct: 72 SSRLKLDEYGLG---HRTYEVNFRAAILARRAA-------ERFATPDHPRFVAGSMGPTG 121
Query: 590 AHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALET 724
S D + + TS + + + + L+E GVD L +ET
Sbjct: 122 ML---PSSSDPALGNITS-DALERIFFEQAKGLIEGGVDALIIET 162
>UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=60;
Bacilli|Rep: Methylenetetrahydrofolate reductase -
Bacillus halodurans
Length = 618
Score = 41.9 bits (94), Expect = 0.031
Identities = 50/193 (25%), Positives = 85/193 (44%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P ++V H+ ++ AGAD+I TNTY A+ ++ +Q E+ AV+LA++A
Sbjct: 38 TDPEKIVAAHVAYVEAGADVIQTNTYAANRMKLAKY--QLDDQVLEINRAAVRLARKAAK 95
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
+E ++G++G G E + I+ +++ +++ALV
Sbjct: 96 ---QE----------TFVLGTIG--GIRSVQFEEVE--------IQEVQDVFLEQMKALV 132
Query: 692 EAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWE 871
GVD L LET EEA+ L R S + + G+ ++ +
Sbjct: 133 SEGVDGLLLETFYDLEEAKLAVSLARSLTDLPVIAHLSIAEIGVLQGGKLLEEAFAELEG 192
Query: 872 LNPDQLVAVGVNC 910
L D VG+NC
Sbjct: 193 LGAD---LVGINC 202
>UniRef50_Q6AL45 Cluster: Related to
5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Desulfotalea psychrophila|Rep:
Related to 5-methyltetrahydrofolate--homocysteine
methyltransferase - Desulfotalea psychrophila
Length = 316
Score = 41.9 bits (94), Expect = 0.031
Identities = 49/170 (28%), Positives = 83/170 (48%), Gaps = 2/170 (1%)
Frame = +2
Query: 236 IVVLDGGFSTQL-SCHVGHVIDGDPLWSARFIH-THPNEVVNTHLDFLRAGADLIITNTY 409
+++ DG T L S ++ GD F++ + P ++ H FL AGA ++ TNT+
Sbjct: 8 LLIFDGACGTTLQSMNIAPSAWGDLAGCNEFLNISAPEYIIELHKKFLEAGAMVVETNTF 67
Query: 410 QASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYG 589
AS E+ G+ + E+ AV+ AK+A + + +D Q I GS+GP
Sbjct: 68 GASSIVLTEY-GLENKVD-EINREAVKNAKKA----ISQLKDSSQP---RYIAGSIGPTT 118
Query: 590 AHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQE 739
G + +T + + + R ++ +L+EAGVD L +ET CQ+
Sbjct: 119 KLPSLG------HIET---KVLAQSIREQVISLLEAGVDALIVET--CQD 157
>UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family
protein; n=9; Rhodobacteraceae|Rep: Homocysteine
S-methyltransferase family protein - Silicibacter
pomeroyi
Length = 298
Score = 41.9 bits (94), Expect = 0.031
Identities = 66/233 (28%), Positives = 92/233 (39%), Gaps = 8/233 (3%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
I +LDG +L G PLWS + P V H D+ AGA + TNTY A
Sbjct: 4 ITLLDGSIGQELVKRAGK--RPTPLWSTSVMLEAPYHVGAVHRDYFDAGATIATTNTY-A 60
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
+ +E G+ ++ LI A+ A+ AR + I G++GP GA
Sbjct: 61 VLRDRLEPAGI-GDRFEALIDTALDQAESARAAH-----------GSGRIAGALGPLGAS 108
Query: 596 LHDG-----SEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCD 760
E + YAD S+ M + VDL +ET +AE
Sbjct: 109 YRPDICPPPEEAEALYAD--SVRAMND------------RVDLFLIETAASVAQAEGA-- 152
Query: 761 LLREFPGTK-AWLAFSCKDDQS--IAHGESFQKVAKKCWELNPDQLVAVGVNC 910
L GTK WL+ + DD + GE ++A + P AV VNC
Sbjct: 153 LRGASLGTKPVWLSVTVMDDDGSRLRSGEGVGELAAIVKQYQPQ---AVLVNC 202
>UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=2;
Acidobacteria|Rep: Methylenetetrahydrofolate reductase -
Acidobacteria bacterium (strain Ellin345)
Length = 617
Score = 41.9 bits (94), Expect = 0.031
Identities = 46/194 (23%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
+ P + H D++ GA+++ TNT+ A+ H +E+ ++ V+L ++A
Sbjct: 41 SQPELIGGIHADYVANGAEILETNTFGANSFRLARH--GCQEKLADINRAGVELVRKA-- 96
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
++N+ + G+VGP G + + TS + R+ R +I+ LV
Sbjct: 97 ---------IKNNQV-YAAGAVGPLGIRIEPLGK--------TSRDEARDAFRDQIRVLV 138
Query: 692 EAGVDLLALETIPCQEEAETLCDLLREF-PGTKAWLAFSCKDDQSIAHGESFQKVAKKCW 868
++GVDLL LET E R+ P + +D + G S + +
Sbjct: 139 DSGVDLLILETFGYLGELHQAILAARDVDPKIPVVAQVTIDEDGNCLDGSSPEHYGARLT 198
Query: 869 ELNPDQLVAVGVNC 910
E D +G NC
Sbjct: 199 EWGAD---VIGCNC 209
>UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Lentisphaera araneosa
HTCC2155|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Lentisphaera araneosa HTCC2155
Length = 1204
Score = 41.9 bits (94), Expect = 0.031
Identities = 52/189 (27%), Positives = 89/189 (47%), Gaps = 26/189 (13%)
Frame = +2
Query: 236 IVVLDG--GFSTQLSCHVGHVIDGDP--LWSARFIHTHPNEVV-NTHLDFLRAGADLIIT 400
I+VLDG G QL G+ + S + + P++V N HL++L+AGA+++ T
Sbjct: 11 ILVLDGAMGSMVQLLKLPDSAYGGEEYAMLSDLLVFSRPDQVRDNIHLEYLKAGANILET 70
Query: 401 NTYQAS-------------VEGFV---EHLGVTKEQGYELI----ARAVQLAKQARTLYL 520
NT+ AS + F E L + Y L R ++LA+ A +
Sbjct: 71 NTFGASPLRLQEFDFSKMDLSDFADLPEGLDFLENDYYALTHYFNIRGIELAQDA----I 126
Query: 521 EEYRDYVQNDDIPLIV-GSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEA 697
E+Y+ + D PL V GS+GP + + + T T+++ +++A+++A
Sbjct: 127 EKYKKMDEYDGRPLFVAGSIGPSNWVISS----TAANLNKTDFATIKQNFYLQVKAMMQA 182
Query: 698 GVDLLALET 724
VD+L ET
Sbjct: 183 NVDVLLFET 191
>UniRef50_Q8DCJ7 Cluster: Methionine synthase; n=51; Bacteria|Rep:
Methionine synthase - Vibrio vulnificus
Length = 1226
Score = 41.9 bits (94), Expect = 0.031
Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 1/133 (0%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P + H +L AGAD++ TNT+ A+ ++ + E+ A +LA++A
Sbjct: 60 TQPQLIKEIHHAYLEAGADILETNTFNATTIAMADY--DMESLSEEINFAAARLAREA-- 115
Query: 512 LYLEEYRDYVQNDDIP-LIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQAL 688
+E+ QN P + G +GP + + S + + E + +AL
Sbjct: 116 --ADEWT--AQNPAKPRYVAGVLGPTNRTCSISPDVNDPGYRNVSFDELVEAYSESTRAL 171
Query: 689 VEAGVDLLALETI 727
+ G DL+ +ETI
Sbjct: 172 IRGGSDLILIETI 184
>UniRef50_Q99707 Cluster: Methionine synthase; n=268; cellular
organisms|Rep: Methionine synthase - Homo sapiens
(Human)
Length = 1265
Score = 41.9 bits (94), Expect = 0.031
Identities = 32/132 (24%), Positives = 65/132 (49%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H ++L AGAD+I TNT+ ++ ++ G+ + Y + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GL-EHLAYRMNMCSAGVARKA-- 128
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
EE +Q + G++GP L + + + + E ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;
Proteobacteria|Rep: Homocysteine S-methyltransferase -
Psychrobacter sp. PRwf-1
Length = 310
Score = 41.5 bits (93), Expect = 0.041
Identities = 60/244 (24%), Positives = 102/244 (41%), Gaps = 8/244 (3%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
I ++DGG +L+ P WSA + P V + H DF+R+GA +I TN+Y
Sbjct: 6 ITIIDGGMGRELAKRGAPF--RQPEWSALAMIEAPEIVRDVHRDFIRSGAGVITTNSY-- 61
Query: 416 SVEGFVEHLGVTK--EQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPL-IVGSVGPY 586
++ F H+G + + +L A A ++A+ A V+ ++ P + GS+ P
Sbjct: 62 ALLPF--HIGEVRFAKHAQDLAASAGEMARAA-----------VELENTPTKVAGSIPP- 107
Query: 587 GAHLHDGSEYDGSY-ADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDL 763
GSY AD E + + P I L VD ET E+ + L
Sbjct: 108 ---------LFGSYRADLFQAEQVEDIATPLITGL-RPYVDFWLAETQSLIAESVAVRKL 157
Query: 764 LREF--PGTKAWLAFSCKDDQ--SIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVS 931
L + W++F+ +D + + S + V + L + A+ NCC +
Sbjct: 158 LTKLDTDNKPVWVSFTLEDSEHLDVPRLRSGETVVEAVTTLAGLNVEAILFNCCQPEVIE 217
Query: 932 NLMK 943
++
Sbjct: 218 QALE 221
>UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2;
Anaeromyxobacter|Rep: Homocysteine S-methyltransferase -
Anaeromyxobacter sp. Fw109-5
Length = 280
Score = 41.1 bits (92), Expect = 0.054
Identities = 61/233 (26%), Positives = 95/233 (40%), Gaps = 2/233 (0%)
Frame = +2
Query: 224 EAPHI-VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIIT 400
EAP +LDGG T L V + L ++ P+ + H D RAGA++++T
Sbjct: 6 EAPGAPTLLDGGMGTAL---VARGLPQGAL-PEEWLLARPDAIAEVHADHARAGAEIVLT 61
Query: 401 NTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVG 580
T+ + + L + + EL A AV+LA+ A + G++G
Sbjct: 62 CTFNLAAPRLAQRLDPPRVE--ELAAIAVRLARGAA--------------PGARVAGALG 105
Query: 581 PYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCD 760
P G + I ++ + +AL AG DLL LET + EA L
Sbjct: 106 PTGL---------AAPGRPAPIRSLAAGYGRAARALAAAGADLLWLETQHDRAEAR-LAL 155
Query: 761 LLREFPGTKAWLAFSC-KDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCA 916
+ G A + F+ D +++ G S ++ L AVGVNC A
Sbjct: 156 VAARATGLDAVVTFTALGDGATLSDGTSVEEALLAMASLGAS---AVGVNCGA 205
>UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 508
Score = 41.1 bits (92), Expect = 0.054
Identities = 22/70 (31%), Positives = 39/70 (55%)
Frame = +2
Query: 353 NTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYR 532
N HL +L AG ++I TNT+Q ++ E G++ + G ++ R + +A +A L Y
Sbjct: 44 NIHLSYLLAGCNVISTNTFQVNLHSLQEK-GISVQDGEGIVDRYIDIAHRA----LLRYE 98
Query: 533 DYVQNDDIPL 562
+++D PL
Sbjct: 99 GIKRSEDFPL 108
>UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 176
Score = 40.3 bits (90), Expect = 0.095
Identities = 44/158 (27%), Positives = 66/158 (41%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
VV DG L G+V+ G W+ +P+ V H +FLRAGAD+I T TY A+
Sbjct: 22 VVGDGSMLITLEKR-GYVMAGS--WTPEATLQYPDAVKQLHREFLRAGADVIQTFTYCAT 78
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
+ K ++ +A L E V N+ L+ GSV A+
Sbjct: 79 EDNLKMKNEHEKNSNDMKSVSVSEINHRACDLARE-----VANEGGALVAGSVSNVNAYR 133
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLL 712
DG+ + E ++ + + LV+ GVD L
Sbjct: 134 KDGACHGAGK------EFVQNEFKKQCDILVKKGVDFL 165
>UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=1;
Lactobacillus plantarum|Rep: Methylenetetrahydrofolate
reductase - Lactobacillus plantarum
Length = 618
Score = 40.3 bits (90), Expect = 0.095
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQAS 418
THP+ ++ H ++RAGAD+I TNTY A+
Sbjct: 38 THPDTILRVHRSYIRAGADIIQTNTYAAN 66
>UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransferase
family protein; n=1; uncultured alpha proteobacterium
EBAC2C11|Rep: Putative homocysteine S-methyltransferase
family protein - uncultured alpha proteobacterium
EBAC2C11
Length = 309
Score = 40.3 bits (90), Expect = 0.095
Identities = 20/60 (33%), Positives = 33/60 (55%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
++LD G ST+L + +G WS ++V TH+ ++ AGAD+I N+Y +S
Sbjct: 18 IILDSGVSTELERRGAKMRNGQ--WSGCVAIDDYEKLVETHIAYIEAGADIITVNSYASS 75
>UniRef50_A7RIN6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 434
Score = 40.3 bits (90), Expect = 0.095
Identities = 45/179 (25%), Positives = 79/179 (44%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 415
+++ DGG S L +V G +W+ + HP V H +FLRAGAD+I T+
Sbjct: 22 VIIGDGGMSHALEKRC-YVKIG--VWTPECVVEHPEAVRQLHSEFLRAGADVIQAFTFAM 78
Query: 416 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 595
+ V GY + +A ++ +E D + L GS+ G+
Sbjct: 79 QDKPLV-------SAGYSYKWDEI---SRAGSILAKEVSD---KGEFALSSGSLCETGSL 125
Query: 596 LHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLRE 772
G + E +++ R +++ V+ G+DLL E I +EAE + ++++E
Sbjct: 126 FIKG---------LATKEEIKQRFRDQVKIFVDTGMDLLIAEYISHVQEAEWMVEVMKE 175
>UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3;
Bacteria|Rep: Homocysteine S-methyltransferase -
Pelagibacter ubique
Length = 302
Score = 39.9 bits (89), Expect = 0.12
Identities = 22/58 (37%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +2
Query: 242 VLDGGFSTQLSCHVGHVIDGDPLWSARFI--HTHPNEVVNTHLDFLRAGADLIITNTY 409
+LDGG +L G +G LWSA + + +++THLDF++AGA++I+T T+
Sbjct: 11 ILDGGMGQELLAR-GMKPNGT-LWSANAVLKEEYHQLLLDTHLDFIKAGAEVIVTATF 66
>UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=3; Desulfovibrio|Rep: Vitamin
B12-dependent methionine synthase family protein -
Desulfovibrio desulfuricans (strain G20)
Length = 841
Score = 39.9 bits (89), Expect = 0.12
Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Frame = +2
Query: 323 FIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQ 502
F ++P + HLD+ RAGAD++ TNT+ + E + V E E+ A A Q
Sbjct: 69 FCLSNPAVLQGVHLDYARAGADVLTTNTFGGTRLKLPEGMNVV-EFNREMARAAKAAAGQ 127
Query: 503 A-RTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRI 679
A RT++ + GSVGP G + + + +++ I R +I
Sbjct: 128 AGRTVF---------------VAGSVGPTGHFVKPLGDLE--FSELVDI------FREQI 164
Query: 680 QALVEAGVDLLALET 724
+ LV+ G+DL+ ET
Sbjct: 165 RGLVQGGIDLVLAET 179
>UniRef50_Q161X1 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Roseobacter denitrificans OCh 114|Rep:
Homocysteine S-methyltransferase, putative - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 305
Score = 39.9 bits (89), Expect = 0.12
Identities = 41/150 (27%), Positives = 65/150 (43%)
Frame = +2
Query: 461 GYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTT 640
GY+ R V++ K A +L +EE R DD+ L+ +GP HD Y G
Sbjct: 87 GYDA-GRLVEVNKDAVSL-MEEVRRTANRDDV-LVSACIGPR----HD--PYAG--IPPV 135
Query: 641 SIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQ 820
S+E R +H+ ++Q+L + VDL+ T EA C L + ++ + D
Sbjct: 136 SVEDARHYHKAQMQSLHDTSVDLVTAYTFNRPSEAAG-CILAAQDAKLPIIMSLVVETDG 194
Query: 821 SIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
+A G +V + E + VNC
Sbjct: 195 CLADGSRLVEVIDQIDEATNSAALFFMVNC 224
>UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Prochlorococcus marinus str. MIT
9211|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Prochlorococcus marinus str. MIT
9211
Length = 1191
Score = 39.9 bits (89), Expect = 0.12
Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 4/181 (2%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVID--GDPLWSAR--FIHTHPNEVVNTHLDFLRAGADLIITN 403
I+V DGG T L D G + ++P V H +L G D+I TN
Sbjct: 13 ILVFDGGMGTALQLQELSKEDFGGSQFEGCNEYLLISNPKSVEKVHRSYLEVGCDVIETN 72
Query: 404 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 583
T+ A+ E+ G+ + + Y+L A +K A+TL ++Y + GS+GP
Sbjct: 73 TFGATSVVLAEY-GL-ENKAYQLNLAA---SKMAKTL----AKEYSTINKPRYAAGSIGP 123
Query: 584 YGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDL 763
L D + D T+ ++ +++AL+ G+DL+ +ET CQ+ + L
Sbjct: 124 -TTKLPTLGHID--FDDLTNS------YQEQVEALITGGIDLVLVET--CQDVLQIKSAL 172
Query: 764 L 766
L
Sbjct: 173 L 173
>UniRef50_Q8R927 Cluster: Methionine synthase I, cobalamin-binding
domain; n=14; Clostridia|Rep: Methionine synthase I,
cobalamin-binding domain - Thermoanaerobacter
tengcongensis
Length = 803
Score = 39.1 bits (87), Expect = 0.22
Identities = 59/226 (26%), Positives = 98/226 (43%), Gaps = 1/226 (0%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVV-NTHLDFLRAGADLIITNTYQ 412
+VV DG TQL G P +I+ EVV + H ++ AGA++I TNT+
Sbjct: 12 VVVFDGAMGTQLQ-ERGLKAGECP----EYINLKMPEVVFDIHKAYIEAGAEVIETNTFG 66
Query: 413 ASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGA 592
A+ ++ G+ +++ E++ + V++A++A D P+ + SVGP G
Sbjct: 67 ANRIKLAKY-GL-EDKVEEIVTKGVEIARKAA-------------GDRPVAL-SVGPTG- 109
Query: 593 HLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLRE 772
E + D T E E + + A +AG D++ +ET+ EA+ +E
Sbjct: 110 ------ELLAPFGDMTFDEAY-EVFKEVVVAAEKAGADIVIIETMSDMLEAKAAILAAKE 162
Query: 773 FPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
K + ++D G V L D A+GVNC
Sbjct: 163 NTNMKVICTMTFQEDGRTLMGSDPVTVVVSLQGLGLD---AIGVNC 205
>UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep:
Methionine synthase - Magnetococcus sp. (strain MC-1)
Length = 1220
Score = 39.1 bits (87), Expect = 0.22
Identities = 29/132 (21%), Positives = 58/132 (43%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P + N H +L AGAD++ TNT+ + ++ G+ + YE+ ++A+QA
Sbjct: 63 TKPQVIRNIHTAYLEAGADIVETNTFNGNAPSLGDY-GL-EALVYEVNLEGARVARQACD 120
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
+ + Q I + G +GP + + + + + + L+
Sbjct: 121 AVMAQ-----QPGRICFVAGVLGPTNRTCSISPDVNNPGFRNIDFDALVADYANGTRGLL 175
Query: 692 EAGVDLLALETI 727
+ G D+L +ET+
Sbjct: 176 DGGADILLVETV 187
>UniRef50_Q9I2Q2 Cluster: Methionine synthase; n=95; Bacteria|Rep:
Methionine synthase - Pseudomonas aeruginosa
Length = 1234
Score = 39.1 bits (87), Expect = 0.22
Identities = 31/132 (23%), Positives = 58/132 (43%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
+ P+ + +L AGAD++ TNT+ A+ ++ G+ + YEL +LA+Q
Sbjct: 66 SRPDVIQAIEKAYLDAGADILETNTFNATQVSQADY-GM-QSLAYELNVEGARLARQVAD 123
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
E D + + G +GP + + + + + E + + L+
Sbjct: 124 AKTAETPDKPR-----FVAGVLGPTSRTCSISPDVNNPGYRNVTFDELVENYVEATRGLI 178
Query: 692 EAGVDLLALETI 727
E G DL+ +ETI
Sbjct: 179 EGGADLILIETI 190
>UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=1;
Victivallis vadensis ATCC BAA-548|Rep:
Methylenetetrahydrofolate reductase - Victivallis
vadensis ATCC BAA-548
Length = 595
Score = 38.7 bits (86), Expect = 0.29
Identities = 48/195 (24%), Positives = 88/195 (45%), Gaps = 2/195 (1%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARA-VQLAKQAR 508
T P+ +++ H +L+AGA+++ TNTY A+ + G++++ E I RA V+LA++A
Sbjct: 30 TAPDVILDIHHQYLKAGAEVLTTNTYNANSRRLAK-FGLSEQT--EAINRAGVKLAREAA 86
Query: 509 TLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQAL 688
L+ SVGP G E D T E + E +I+AL
Sbjct: 87 A-------------GKALVAASVGPVG-------EPDSDQDRRTRAELLAE----QIRAL 122
Query: 689 VEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCW 868
+A D + E++ + + + + + EFP +F+ + I + + ++
Sbjct: 123 SDA--DFIIFESLRRAADLKAVLEAVAEFPELVYVPSFAIEPHPHINDSATIAEFMEQLN 180
Query: 869 ELNP-DQLVAVGVNC 910
P A+G+NC
Sbjct: 181 ASRPCPAPTAIGLNC 195
>UniRef50_Q2AGF5 Cluster: Dihydropteroate synthase,
DHPS:Homocysteine S- methyltransferase:Methionine
synthase, B12-binding module, cap:Cobalamin B12-binding;
n=1; Halothermothrix orenii H 168|Rep: Dihydropteroate
synthase, DHPS:Homocysteine S-
methyltransferase:Methionine synthase, B12-binding
module, cap:Cobalamin B12-binding - Halothermothrix
orenii H 168
Length = 819
Score = 38.3 bits (85), Expect = 0.38
Identities = 47/183 (25%), Positives = 83/183 (45%), Gaps = 3/183 (1%)
Frame = +2
Query: 236 IVVLDGGFSTQL-SCHV--GHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNT 406
I++ DG T L +C + GH + W + P+ + H +++ AGA LI TNT
Sbjct: 13 IIIGDGAMGTMLQACGLSSGHAPES---WVIK----KPDTIYKIHKEYVAAGAGLIETNT 65
Query: 407 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 586
+ A+ ++ LG+ +++ E+ +A LA++A + GSVGP
Sbjct: 66 FGAN-RLKLKSLGL-EDKIEEINVKATGLARKAAGKV--------------FVAGSVGPT 109
Query: 587 GAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLL 766
G + + S + R+ + +I LV AGVD++ +ET+ +E
Sbjct: 110 GKLMEPHGD--------LSFDRARDVFKEQISYLVHAGVDVVIIETMSDLKELRAAVVAA 161
Query: 767 REF 775
+EF
Sbjct: 162 KEF 164
>UniRef50_Q1NSQ8 Cluster: Methylenetetrahydrofolate reductase; n=2;
delta proteobacterium MLMS-1|Rep:
Methylenetetrahydrofolate reductase - delta
proteobacterium MLMS-1
Length = 704
Score = 37.9 bits (84), Expect = 0.50
Identities = 40/135 (29%), Positives = 64/135 (47%)
Frame = +2
Query: 338 PNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 517
P+ + + H +++RAG+ LI TNT+ A+ + + G+ + Q E+ +AK+A
Sbjct: 118 PDLIYSLHEEYIRAGSQLIETNTFGANRLKLLAN-GL-ENQAREINLAGAGIAKRA---- 171
Query: 518 LEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEA 697
+DI + GSVGP G E+ + E + +I AL+EA
Sbjct: 172 --------AGEDI-YVAGSVGPTGV------EFPLEAGEIEPAEVAAAYEE-QISALLEA 215
Query: 698 GVDLLALETIPCQEE 742
VDLL LET +E
Sbjct: 216 EVDLLILETFTHLDE 230
>UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=2; Epsilonproteobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Nitratiruptor sp. (strain SB155-2)
Length = 1148
Score = 37.9 bits (84), Expect = 0.50
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVI----DGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITN 403
I+++DG TQL + +G + T P + + H + + GAD+I TN
Sbjct: 10 ILIIDGAMGTQLQAKANEISADVWEGKEGCNELLNRTAPKVIKSIHEAYAKVGADIIKTN 69
Query: 404 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 517
T+ S+ ++ + E Y+L R +L K+ Y
Sbjct: 70 TF-GSMPWVLDEYDLASE-AYDLTKRGCELVKEVCETY 105
>UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Beggiatoa sp. PS|Rep:
5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Beggiatoa sp. PS
Length = 157
Score = 37.5 bits (83), Expect = 0.67
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 505
T P+ + H +L AGAD+I TNT+ A+ ++ +E YEL +LA++A
Sbjct: 58 TQPHIIKEIHTQYLEAGADIIETNTFNATRIAMADYR--MEELVYELNVAGAKLAREA 113
>UniRef50_A0RW49 Cluster: Methionine synthase I
(Cobalamin-dependent), methyltransferase domain; n=1;
Cenarchaeum symbiosum|Rep: Methionine synthase I
(Cobalamin-dependent), methyltransferase domain -
Cenarchaeum symbiosum
Length = 317
Score = 37.5 bits (83), Expect = 0.67
Identities = 36/143 (25%), Positives = 66/143 (46%)
Frame = +2
Query: 296 DGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELI 475
DG ++ + + P + H ++ AGAD I TN++ ++ K Y
Sbjct: 38 DGKEGFNDGLVLSRPEWISKIHRSYIEAGADCIETNSFGSN---------KIKLDEYGFG 88
Query: 476 ARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETM 655
R V++ ++A +L E V+ D +VGS+GP G +L ++ D ++T+
Sbjct: 89 ERTVEINEKAASLAAAE-AGRVERD--VYVVGSMGPTG-YLPSSNDPD---LGQIPLDTI 141
Query: 656 REWHRPRIQALVEAGVDLLALET 724
++ + + LV G D L +ET
Sbjct: 142 QDAFALQAEGLVRGGADALIIET 164
>UniRef50_Q1WUH1 Cluster: TRNA delta(2)-isopentenylpyrophosphate
transferase; n=5; Lactobacillales|Rep: TRNA
delta(2)-isopentenylpyrophosphate transferase -
Lactobacillus salivarius subsp. salivarius (strain
UCC118)
Length = 307
Score = 37.1 bits (82), Expect = 0.88
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = +2
Query: 521 EEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREW 664
++ ++ +D+IP+IVG G Y L DG G D SIE ++W
Sbjct: 83 KDIKEIANDDNIPIIVGGTGFYLQALLDGYSLGGDTFDQLSIERRKKW 130
>UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4;
Bacteria|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 826
Score = 37.1 bits (82), Expect = 0.88
Identities = 42/193 (21%), Positives = 75/193 (38%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
TH E+ H ++ AG+D+I+TNT+ A+ F + +E ++ + ++A
Sbjct: 38 THSEEIYKIHRQYIEAGSDIILTNTFGANALKFHDDSCSLEEIIKAAVSHVKKAEREALL 97
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
+E + Y D VGP G L + + ET E + +
Sbjct: 98 QTGDERKIYTALD--------VGPTGKLLKPMGDLE--------FETAYEAFKEVVILGE 141
Query: 692 EAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCWE 871
+AG DL+ +ET+ E + +E + + + + G V
Sbjct: 142 QAGADLIHIETMSDTYELKAAVLAAKENTSLPVFATVIFDERKKLLTGADVSSVVALLEG 201
Query: 872 LNPDQLVAVGVNC 910
L D A+G+NC
Sbjct: 202 LGVD---ALGINC 211
>UniRef50_A7DNT5 Cluster: Homocysteine S-methyltransferase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Homocysteine S-methyltransferase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 320
Score = 37.1 bits (82), Expect = 0.88
Identities = 36/131 (27%), Positives = 62/131 (47%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H +L AGAD I TN++ S + ++ G +Q E + QLA +
Sbjct: 50 TRPDWIKQIHRHYLDAGADCIETNSF-GSNKIKLDEYGF-GDQTIEFNKKIAQLASEV-- 105
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
+EY D + ++GS+GP G L ++ D ++ ++E + + L+
Sbjct: 106 --CQEYSDRPR-----YVIGSMGPSG-FLPSSNDPD---LGQKPLDEIKEAFELQAEGLI 154
Query: 692 EAGVDLLALET 724
GVD L +ET
Sbjct: 155 LGGVDALLIET 165
>UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium falciparum (isolate 3D7)
Length = 581
Score = 35.9 bits (79), Expect = 2.0
Identities = 22/72 (30%), Positives = 40/72 (55%)
Frame = +2
Query: 353 NTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYR 532
N HL +L G ++I TNT+Q ++ F + LG+ + G E++ + + +A + Y E R
Sbjct: 47 NIHLSYLLGGCNIIGTNTFQVNLYSF-KKLGI--DNGEEILNKYINIAYNSLLKYEEIKR 103
Query: 533 DYVQNDDIPLIV 568
DDI +++
Sbjct: 104 K--SKDDINVLL 113
>UniRef50_Q8ESE8 Cluster: Betaine-homocysteine methyltransferase;
n=5; Bacteria|Rep: Betaine-homocysteine
methyltransferase - Oceanobacillus iheyensis
Length = 349
Score = 35.5 bits (78), Expect = 2.7
Identities = 47/194 (24%), Positives = 87/194 (44%), Gaps = 2/194 (1%)
Frame = +2
Query: 335 HPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIAR-AVQLAKQART 511
+P+ + T+ DF+ AG+D+++ TY A E + +G KEQ E + R A++LAK
Sbjct: 43 NPDALKQTYRDFMNAGSDVVLAFTYNAHREK-MRIIG--KEQLLEPLNRSAIRLAK---- 95
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
E +++ Q + L+ G++ ++ D ++ + M +W +
Sbjct: 96 ---EVAKEHPQEE--ALVAGNIS--NTNIFDPNDESSKHKVREMFAEMAQWSK------- 141
Query: 692 EAGVDLLALETIPCQEEAE-TLCDLLREFPGTKAWLAFSCKDDQSIAHGESFQKVAKKCW 868
E VD + ET EEAE L ++L++ A + + + V + C
Sbjct: 142 EEDVDFINGETFYYHEEAEIALEEILKK--DLPAVITLGLMGENIL---RDCYTVEESCK 196
Query: 869 ELNPDQLVAVGVNC 910
L+ + VG+NC
Sbjct: 197 ILSEKGALVVGMNC 210
>UniRef50_A5ZSP9 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 490
Score = 35.1 bits (77), Expect = 3.6
Identities = 27/111 (24%), Positives = 53/111 (47%)
Frame = +2
Query: 311 WSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQ 490
WS + + NE++N L G+ +++ + ++ SV+ ++ + ++GY+L+ +
Sbjct: 298 WSYKDVDKDYNEIMNGDLT---DGSIILMHDIHEPSVQAAIKMIPELVQKGYKLMTVSEL 354
Query: 491 LAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTS 643
A + TL Y D+ D L G V Y + DGS + +D T+
Sbjct: 355 AAAKGVTLQNANYSDFW---DSSLQKGIVAGYNSGSSDGSSDGTAVSDGTT 402
>UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium chabaudi
Length = 504
Score = 35.1 bits (77), Expect = 3.6
Identities = 17/55 (30%), Positives = 32/55 (58%)
Frame = +2
Query: 353 NTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 517
N HL +L +G+++I TNTYQ ++ + ++ E G E+I + +A ++ Y
Sbjct: 45 NIHLSYLLSGSNIITTNTYQVNLH--FKRNNISIENGKEIIDTYIDIAYESCEKY 97
>UniRef50_Q1GGL5 Cluster: Homocysteine S-methyltransferase; n=30;
Bacteria|Rep: Homocysteine S-methyltransferase -
Silicibacter sp. (strain TM1040)
Length = 340
Score = 34.7 bits (76), Expect = 4.7
Identities = 49/182 (26%), Positives = 75/182 (41%)
Frame = +2
Query: 197 MTPPSSENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLR 376
M+ E ++ +++ DG T L D LW+ P+++ + +
Sbjct: 1 MSNSFQELLDSRDVLLADGATGTNLFNMGLQSGDAPELWNT----DAPDKIKALYQGSVD 56
Query: 377 AGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI 556
AG+DL +TN++ G L + QG R +L + A L E D +
Sbjct: 57 AGSDLFLTNSFG----GTAARLKLHDAQG-----RVRELNRIAAELG-REVADKAERKIA 106
Query: 557 PLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQ 736
+ GSVGP G + E + A +E E + AL E GVD+L LETI
Sbjct: 107 --VAGSVGPTGEIMQPVGELSHALA----VEMFHE----QADALKEGGVDVLWLETISAP 156
Query: 737 EE 742
EE
Sbjct: 157 EE 158
>UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2;
Desulfitobacterium hafniense|Rep: Homocysteine
S-methyltransferase - Desulfitobacterium hafniense
(strain DCB-2)
Length = 285
Score = 34.7 bits (76), Expect = 4.7
Identities = 54/225 (24%), Positives = 88/225 (39%), Gaps = 1/225 (0%)
Frame = +2
Query: 239 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 418
V+ DG T L + + G P T P + H +++AG+++I TNT+ A
Sbjct: 9 VIFDGAMGTMLQKY--DLAPGQPPEVLNI--TRPEVIEEVHRKYIKAGSNIITTNTFGA- 63
Query: 419 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 598
+E + G + E E++ A+ +A++A L + L VG G L
Sbjct: 64 IETKLNGTGYSVE---EVVQSAIAIARRAAGKNL-----------VALDVGPTGELIEPL 109
Query: 599 HDGSEYDGSYADTTSIETMREWHRPRIQALVEAG-VDLLALETIPCQEEAETLCDLLREF 775
D S E + + + +I+A G VDL+ +ET EA ++
Sbjct: 110 GD-----------LSFEEVYDLYACQIKAAALTGNVDLVLIETFFDLTEAHAAIRAAKDH 158
Query: 776 PGTKAWLAFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
F+ + G+ + V E D AVGVNC
Sbjct: 159 SSLPVICTFTFQQKGRTLMGKDIKTVVTSLEEYGVD---AVGVNC 200
>UniRef50_A7CWS4 Cluster: Homocysteine S-methyltransferase
precursor; n=7; Bacteria|Rep: Homocysteine
S-methyltransferase precursor - Opitutaceae bacterium
TAV2
Length = 398
Score = 34.3 bits (75), Expect = 6.2
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 2/134 (1%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVE-HLGVTKEQGYELIARAVQLAKQAR 508
T P+ + H + AGAD++ TNT+ ++ + HL + A + A +A
Sbjct: 98 TRPDVIEGIHAAYFAAGADMVETNTFNSTAISQADYHLEPLVTEINTAAAAIARRAVRAT 157
Query: 509 TLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYD-GSYADTTSIETMREWHRPRIQA 685
R +V G++GP L + + Y T + + + +I+A
Sbjct: 158 ETATPGRRCFV--------AGAIGPLNRTLSMSPDVNRPDYRAVTWAQVVAA-YTEQIRA 208
Query: 686 LVEAGVDLLALETI 727
L+ GVD L +ETI
Sbjct: 209 LIAGGVDALLVETI 222
>UniRef50_Q74DI9 Cluster: Homocysteine S-methyltransferase domain
protein; n=2; Deltaproteobacteria|Rep: Homocysteine
S-methyltransferase domain protein - Geobacter
sulfurreducens
Length = 318
Score = 33.9 bits (74), Expect = 8.2
Identities = 29/118 (24%), Positives = 47/118 (39%)
Frame = +2
Query: 629 ADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWLAFSC 808
A+ S + RE+H + AL AGVD L T+P EA L + G ++F
Sbjct: 133 AEALSEDEAREFHSWQADALAAAGVDFLLAATLPALGEAVGLARAMAA-TGMPHVVSFVV 191
Query: 809 KDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNCCARSFVSNLMKGXNDDRPQAPXRL 982
+ ++ G ++ + VA VNC SF + + + P R+
Sbjct: 192 RPGGTLLDGTPLREAVAALDAAVSPRPVAYLVNCTHASFFRSALLHEANSSPLVRQRV 249
>UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine
methyltransferase; n=9; cellular organisms|Rep:
5-Methyltetrahydrofolate-S-homocysteine
methyltransferase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 1168
Score = 33.9 bits (74), Expect = 8.2
Identities = 24/84 (28%), Positives = 41/84 (48%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
+ P V H + AGAD++ TNT+ S+ E G+ +++ E+ A LA++A
Sbjct: 50 SRPELVREIHRGYFEAGADMVETNTFGGSIVTLAE-FGL-QDRTREINRTAATLAREAAE 107
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGP 583
+ + YV +GS+GP
Sbjct: 108 TFADGRHRYV--------MGSIGP 123
>UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep:
Msh - Agrobacterium tumefaciens
Length = 316
Score = 33.9 bits (74), Expect = 8.2
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +2
Query: 236 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 409
+ +LDGG +L + P WSA + P V H F+ AGA++I TN+Y
Sbjct: 5 VTILDGGMGRELLRNGAPF--RQPEWSALSLIEAPEFVKMAHDAFVAAGAEVITTNSY 60
>UniRef50_A5ZUF2 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 289
Score = 33.9 bits (74), Expect = 8.2
Identities = 28/98 (28%), Positives = 41/98 (41%)
Frame = +2
Query: 617 DGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCQEEAETLCDLLREFPGTKAWL 796
DG Y T + +E +I+ L +AG+DL+A ET+ EE D
Sbjct: 117 DGDYTYTEAYNMYQE----QIRILADAGIDLIAAETMINIEETLAAVDAAASVCDLPIMC 172
Query: 797 AFSCKDDQSIAHGESFQKVAKKCWELNPDQLVAVGVNC 910
+ + D SI G + + A D AVG+NC
Sbjct: 173 TMTVEADGSIFSGGNAVEAAVSLEAAGAD---AVGINC 207
>UniRef50_A5Z6N8 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 393
Score = 33.9 bits (74), Expect = 8.2
Identities = 16/45 (35%), Positives = 29/45 (64%)
Frame = +2
Query: 341 NEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELI 475
N V +T L +A +++ + +Q SV+GF++ L K++GYEL+
Sbjct: 324 NYVSSTILKETKAWDIVLLHDIHQTSVDGFIKALPTLKKRGYELV 368
>UniRef50_Q4YA86 Cluster: Putative uncharacterized protein; n=1;
Plasmodium berghei|Rep: Putative uncharacterized protein
- Plasmodium berghei
Length = 71
Score = 33.9 bits (74), Expect = 8.2
Identities = 15/60 (25%), Positives = 30/60 (50%)
Frame = +2
Query: 497 KQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPR 676
K+ +T + + ++ ++ VG + + H H G+++ GSY+ T + WH PR
Sbjct: 9 KKKKTQVTTDAGEDMEKEEYFSTVGGIASW--HNHSGNKFGGSYSTTRGLSYTTPWHLPR 66
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,083,442,853
Number of Sequences: 1657284
Number of extensions: 22457080
Number of successful extensions: 56459
Number of sequences better than 10.0: 126
Number of HSP's better than 10.0 without gapping: 54037
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 56343
length of database: 575,637,011
effective HSP length: 102
effective length of database: 406,594,043
effective search space used: 117912272470
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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