Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_P18
(1180 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC020665-1|AAH20665.1| 363|Homo sapiens betaine-homocysteine me... 45 6e-04
AF257473-1|AAG41356.1| 363|Homo sapiens betaine-homocysteine me... 45 6e-04
U50929-1|AAC50668.1| 406|Homo sapiens betaine:homocysteine meth... 44 8e-04
BC012616-1|AAH12616.1| 406|Homo sapiens betaine-homocysteine me... 44 8e-04
AF118378-1|AAD22043.1| 406|Homo sapiens betaine-homocysteine me... 44 8e-04
U75743-1|AAB58906.1| 1265|Homo sapiens methionine synthase protein. 42 0.004
U73338-1|AAB39704.1| 1265|Homo sapiens methionine synthase protein. 42 0.004
U71285-1|AAC51188.1| 1265|Homo sapiens 5-methyltetrahydrofolate-... 42 0.004
BC130616-1|AAI30617.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 42 0.004
AL359259-1|CAH70983.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 42 0.004
AL359185-1|CAH73198.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 42 0.004
>BC020665-1|AAH20665.1| 363|Homo sapiens betaine-homocysteine
methyltransferase 2 protein.
Length = 363
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/68 (36%), Positives = 39/68 (57%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E E+ +V+ DG F L G+V G LW+ + HP+ V H++FLRAG++++
Sbjct: 15 ERLESGEVVIGDGSFLITLEKR-GYVKAG--LWTPEAVIEHPDAVRQLHMEFLRAGSNVM 71
Query: 395 ITNTYQAS 418
T T+ AS
Sbjct: 72 QTFTFSAS 79
>AF257473-1|AAG41356.1| 363|Homo sapiens betaine-homocysteine
methyltransferase 2 protein.
Length = 363
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/68 (36%), Positives = 39/68 (57%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E E+ +V+ DG F L G+V G LW+ + HP+ V H++FLRAG++++
Sbjct: 15 ERLESGEVVIGDGSFLITLEKR-GYVKAG--LWTPEAVIEHPDAVRQLHMEFLRAGSNVM 71
Query: 395 ITNTYQAS 418
T T+ AS
Sbjct: 72 QTFTFSAS 79
>U50929-1|AAC50668.1| 406|Homo sapiens betaine:homocysteine
methyltransferase protein.
Length = 406
Score = 44.4 bits (100), Expect = 8e-04
Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E A IV+ DGGF L G+V G W+ HP V H +FLRAG++++
Sbjct: 15 ERLNAGEIVIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVM 71
Query: 395 ITNTYQASVEGFVEHLG---VTKEQGYELIARAVQLAKQ 502
T T+ AS E +E+ G + K G E+ A +A+Q
Sbjct: 72 QTFTFYAS-EDKLENRGNYVLEKISGQEVNEAACDIARQ 109
>BC012616-1|AAH12616.1| 406|Homo sapiens betaine-homocysteine
methyltransferase protein.
Length = 406
Score = 44.4 bits (100), Expect = 8e-04
Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E A IV+ DGGF L G+V G W+ HP V H +FLRAG++++
Sbjct: 15 ERLNAGEIVIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVM 71
Query: 395 ITNTYQASVEGFVEHLG---VTKEQGYELIARAVQLAKQ 502
T T+ AS E +E+ G + K G E+ A +A+Q
Sbjct: 72 QTFTFYAS-EDKLENRGNYVLEKISGQEVNEAACDIARQ 109
>AF118378-1|AAD22043.1| 406|Homo sapiens betaine-homocysteine
methyltransferase protein.
Length = 406
Score = 44.4 bits (100), Expect = 8e-04
Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 215 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 394
E A IV+ DGGF L G+V G W+ HP V H +FLRAG++++
Sbjct: 15 ERLNAGEIVIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVM 71
Query: 395 ITNTYQASVEGFVEHLG---VTKEQGYELIARAVQLAKQ 502
T T+ AS E +E+ G + K G E+ A +A+Q
Sbjct: 72 QTFTFYAS-EDKLENRGNYVLEKISGQEVNEAACDIARQ 109
>U75743-1|AAB58906.1| 1265|Homo sapiens methionine synthase protein.
Length = 1265
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/132 (24%), Positives = 65/132 (49%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H ++L AGAD+I TNT+ ++ ++ G+ + Y + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GL-EHLAYRMNMCSAGVARKA-- 128
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
EE +Q + G++GP L + + + + E ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>U73338-1|AAB39704.1| 1265|Homo sapiens methionine synthase protein.
Length = 1265
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/132 (24%), Positives = 65/132 (49%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H ++L AGAD+I TNT+ ++ ++ G+ + Y + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GL-EHLAYRMNMCSAGVARKA-- 128
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
EE +Q + G++GP L + + + + E ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>U71285-1|AAC51188.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/132 (24%), Positives = 65/132 (49%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H ++L AGAD+I TNT+ ++ ++ G+ + Y + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GL-EHLAYRMNMCSAGVARKA-- 128
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
EE +Q + G++GP L + + + + E ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>BC130616-1|AAI30617.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/132 (24%), Positives = 65/132 (49%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H ++L AGAD+I TNT+ ++ ++ G+ + Y + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GL-EHLAYRMNMCSAGVARKA-- 128
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
EE +Q + G++GP L + + + + E ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>AL359259-1|CAH70983.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/132 (24%), Positives = 65/132 (49%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H ++L AGAD+I TNT+ ++ ++ G+ + Y + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GL-EHLAYRMNMCSAGVARKA-- 128
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
EE +Q + G++GP L + + + + E ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>AL359185-1|CAH73198.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/132 (24%), Positives = 65/132 (49%)
Frame = +2
Query: 332 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 511
T P+ + H ++L AGAD+I TNT+ ++ ++ G+ + Y + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GL-EHLAYRMNMCSAGVARKA-- 128
Query: 512 LYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIETMREWHRPRIQALV 691
EE +Q + G++GP L + + + + E ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 692 EAGVDLLALETI 727
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 159,791,244
Number of Sequences: 237096
Number of extensions: 3543515
Number of successful extensions: 6663
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6339
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6657
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 16513869000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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