Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_M08
(1215 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK057735-1|BAB71555.1| 274|Homo sapiens protein ( Homo sapiens ... 154 5e-37
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 140 7e-33
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 140 7e-33
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 140 7e-33
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 139 2e-32
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 139 2e-32
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 139 2e-32
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 139 2e-32
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 139 2e-32
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 139 2e-32
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 139 2e-32
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 139 2e-32
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 137 9e-32
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 137 9e-32
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 137 9e-32
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 137 9e-32
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 136 2e-31
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 136 2e-31
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 134 8e-31
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 134 8e-31
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 134 8e-31
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 134 8e-31
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 134 8e-31
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 134 8e-31
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 134 8e-31
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 134 8e-31
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 134 8e-31
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 134 8e-31
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 133 1e-30
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 132 2e-30
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 132 2e-30
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 132 2e-30
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 132 2e-30
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 131 4e-30
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 131 4e-30
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 131 4e-30
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 131 4e-30
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 131 4e-30
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 131 4e-30
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 130 8e-30
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 130 8e-30
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 130 8e-30
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 130 1e-29
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 130 1e-29
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 130 1e-29
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 130 1e-29
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 130 1e-29
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 130 1e-29
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 130 1e-29
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 128 3e-29
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 128 3e-29
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 128 3e-29
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 128 3e-29
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 128 3e-29
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 128 3e-29
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 128 3e-29
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 128 4e-29
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 128 4e-29
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 128 4e-29
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 128 4e-29
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 127 7e-29
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 127 7e-29
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 127 7e-29
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 127 7e-29
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 127 7e-29
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 127 7e-29
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 127 9e-29
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 126 1e-28
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 126 1e-28
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 126 1e-28
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 126 2e-28
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 126 2e-28
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 126 2e-28
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 126 2e-28
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 126 2e-28
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 126 2e-28
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 126 2e-28
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 126 2e-28
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 126 2e-28
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 126 2e-28
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 125 4e-28
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 125 4e-28
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 125 4e-28
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 124 5e-28
BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein. 124 5e-28
BC009107-1|AAH09107.1| 879|Homo sapiens microtubule associated ... 124 5e-28
BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein. 124 5e-28
AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated ... 124 5e-28
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 124 5e-28
AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated ... 124 5e-28
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 124 5e-28
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 124 5e-28
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 124 5e-28
AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated ... 124 5e-28
AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated ... 124 5e-28
AL160291-7|CAI16908.1| 878|Homo sapiens novel protein kinase do... 124 5e-28
AL160291-6|CAI16909.1| 879|Homo sapiens novel protein kinase do... 124 5e-28
AL160291-5|CAI16910.1| 840|Homo sapiens novel protein kinase do... 124 5e-28
AK074804-1|BAC11218.1| 840|Homo sapiens protein ( Homo sapiens ... 124 5e-28
AK027719-1|BAB55321.1| 878|Homo sapiens protein ( Homo sapiens ... 124 5e-28
AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein. 124 5e-28
AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein. 124 5e-28
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 124 7e-28
M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha pr... 124 7e-28
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 124 7e-28
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 124 7e-28
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 124 7e-28
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 124 9e-28
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 124 9e-28
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 123 1e-27
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 123 1e-27
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 123 1e-27
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 123 1e-27
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 123 1e-27
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 123 1e-27
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 123 1e-27
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 123 2e-27
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 123 2e-27
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 123 2e-27
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 123 2e-27
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 123 2e-27
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 123 2e-27
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 123 2e-27
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 123 2e-27
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 123 2e-27
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 123 2e-27
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 123 2e-27
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 123 2e-27
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 122 2e-27
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 122 2e-27
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 122 2e-27
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 122 2e-27
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 122 2e-27
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 122 2e-27
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 122 3e-27
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 122 3e-27
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 122 3e-27
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 122 3e-27
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 122 3e-27
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 122 3e-27
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 122 3e-27
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 122 3e-27
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 122 3e-27
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 122 3e-27
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 122 3e-27
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 122 3e-27
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 122 3e-27
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 122 3e-27
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 121 5e-27
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 121 6e-27
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 120 8e-27
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 120 8e-27
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 120 8e-27
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 120 8e-27
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 120 8e-27
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 120 8e-27
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 120 8e-27
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 120 1e-26
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 120 1e-26
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 120 1e-26
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 120 1e-26
AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta ... 120 1e-26
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 120 1e-26
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 120 1e-26
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 120 1e-26
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 120 1e-26
AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-... 120 1e-26
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 120 1e-26
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 120 1e-26
AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protei... 120 1e-26
AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein. 120 1e-26
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 119 2e-26
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 119 2e-26
BC028603-1|AAH28603.1| 464|Homo sapiens serine/threonine kinase... 119 2e-26
AB023182-1|BAA76809.2| 489|Homo sapiens KIAA0965 protein protein. 119 2e-26
Z85986-3|CAB39180.1| 465|Homo sapiens serine/threonine kinase 3... 119 2e-26
Z35102-1|CAA84485.1| 465|Homo sapiens Ndr protein kinase protein. 119 2e-26
BC095413-1|AAH95413.1| 465|Homo sapiens serine/threonine kinase... 119 2e-26
BC012085-1|AAH12085.1| 465|Homo sapiens serine/threonine kinase... 119 2e-26
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 118 3e-26
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 118 3e-26
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 118 3e-26
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 117 7e-26
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 117 7e-26
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 117 7e-26
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 117 7e-26
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 117 7e-26
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 117 7e-26
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 117 7e-26
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 117 7e-26
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 117 7e-26
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 117 7e-26
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 117 7e-26
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 117 7e-26
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 117 7e-26
AL356285-1|CAI15861.1| 1088|Homo sapiens LATS, large tumor suppr... 117 1e-25
AL161613-1|CAH71526.1| 1088|Homo sapiens LATS, large tumor suppr... 117 1e-25
AB209897-1|BAD93134.1| 924|Homo sapiens LATS, large tumor suppr... 117 1e-25
AB028019-1|BAA92381.1| 1046|Homo sapiens large tumor suppressor ... 117 1e-25
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 116 1e-25
BC028079-1|AAH28079.1| 556|Homo sapiens RPS6KA4 protein protein. 116 1e-25
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 116 1e-25
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 116 1e-25
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 116 1e-25
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 116 2e-25
AF207547-1|AAF80561.1| 1088|Homo sapiens serine/threonine kinase... 116 2e-25
BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein. 115 3e-25
AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein. 115 3e-25
AF164041-1|AAD50272.1| 1130|Homo sapiens WARTS protein kinase pr... 115 3e-25
AF104413-1|AAD16882.1| 1130|Homo sapiens large tumor suppressor ... 115 3e-25
AB209426-1|BAD92663.1| 830|Homo sapiens LATS homolog 1 variant ... 115 3e-25
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 115 4e-25
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 115 4e-25
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 114 5e-25
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 114 5e-25
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 114 5e-25
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 114 5e-25
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 114 5e-25
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 114 7e-25
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 114 7e-25
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 114 7e-25
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 114 7e-25
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 114 7e-25
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 114 7e-25
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 114 7e-25
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 114 7e-25
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 114 7e-25
AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta ... 114 7e-25
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 113 9e-25
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 113 9e-25
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 113 9e-25
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 113 9e-25
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 113 9e-25
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 113 9e-25
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 112 2e-24
S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase p... 112 3e-24
M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein. 112 3e-24
L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein. 112 3e-24
L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase... 112 3e-24
L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase... 112 3e-24
L08835-3|AAC14448.1| 624|Homo sapiens myotonic dystrophy kinase... 112 3e-24
L08835-2|AAC14449.1| 629|Homo sapiens myotonic dystrophy kinase... 112 3e-24
L00727-5|AAA75237.1| 545|Homo sapiens myotonin-protein kinase, ... 112 3e-24
L00727-3|AAA75239.1| 634|Homo sapiens myotonin-protein kinase, ... 112 3e-24
L00727-2|AAA75238.1| 609|Homo sapiens myotonin-protein kinase, ... 112 3e-24
L00727-1|AAA75236.1| 639|Homo sapiens myotonin-protein kinase, ... 112 3e-24
BC062553-1|AAH62553.1| 629|Homo sapiens DMPK protein protein. 112 3e-24
BC026328-1|AAH26328.1| 655|Homo sapiens DMPK protein protein. 112 3e-24
AB209363-1|BAD92600.1| 672|Homo sapiens myotonic dystrophy prot... 112 3e-24
L00727-4|AAA75235.1| 589|Homo sapiens myotonin-protein kinase, ... 111 5e-24
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 111 5e-24
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 111 5e-24
U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK... 111 7e-24
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 111 7e-24
AY166586-1|AAN86031.1| 1638|Homo sapiens CDC42-binding protein k... 111 7e-24
AL627308-5|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 111 7e-24
AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein k... 111 7e-24
AL627308-3|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 111 7e-24
AL451047-3|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 111 7e-24
AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein k... 111 7e-24
AL451047-1|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 111 7e-24
AL353689-9|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 111 7e-24
AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein k... 111 7e-24
AL353689-7|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 111 7e-24
AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein k... 111 7e-24
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 111 7e-24
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 111 7e-24
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 110 9e-24
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 110 9e-24
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 110 9e-24
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 110 9e-24
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 110 9e-24
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 110 9e-24
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 110 9e-24
BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein. 110 9e-24
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 110 9e-24
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 110 9e-24
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 110 9e-24
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 110 9e-24
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 110 9e-24
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 110 9e-24
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 110 9e-24
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 110 9e-24
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 110 9e-24
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 110 9e-24
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 110 9e-24
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 110 9e-24
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 110 9e-24
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 95 2e-23
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 108 3e-23
AF208004-1|AAG35720.1| 181|Homo sapiens cAMP-dependent protein ... 108 3e-23
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 108 5e-23
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 108 5e-23
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 108 5e-23
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 108 5e-23
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 107 8e-23
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 107 8e-23
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 107 1e-22
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 107 1e-22
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 107 1e-22
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 107 1e-22
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 106 1e-22
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 106 1e-22
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 106 1e-22
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 106 1e-22
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 106 1e-22
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 106 1e-22
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 106 2e-22
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 106 2e-22
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 105 2e-22
AL450063-5|CAI16848.1| 186|Homo sapiens protein kinase, cAMP-de... 105 3e-22
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 105 4e-22
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 105 4e-22
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 105 4e-22
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 105 4e-22
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 105 4e-22
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 105 4e-22
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 105 4e-22
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 103 1e-21
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 103 1e-21
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 103 1e-21
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 103 1e-21
BC021666-1|AAH21666.1| 166|Homo sapiens serine/threonine kinase... 102 2e-21
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 101 5e-21
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 101 5e-21
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 101 5e-21
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 101 7e-21
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 100 9e-21
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 100 9e-21
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 100 9e-21
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 100 1e-20
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 100 1e-20
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 100 1e-20
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 100 1e-20
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 100 1e-20
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 100 1e-20
M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein. 99 4e-20
BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein. 99 4e-20
BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, recep... 99 4e-20
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 98 5e-20
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 98 5e-20
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 98 5e-20
X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor ... 97 9e-20
U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor ... 97 9e-20
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 97 9e-20
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 97 9e-20
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 97 1e-19
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 97 1e-19
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 97 1e-19
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 97 1e-19
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 97 1e-19
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 97 1e-19
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 97 1e-19
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 96 3e-19
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 96 3e-19
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 96 3e-19
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 96 3e-19
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 96 3e-19
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 96 3e-19
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 96 3e-19
BC045760-1|AAH45760.1| 369|Homo sapiens STK32C protein protein. 95 3e-19
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 95 3e-19
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 95 3e-19
AL512622-6|CAI12187.1| 369|Homo sapiens protein kinase (PKE) pr... 95 3e-19
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 95 3e-19
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 95 3e-19
BC036797-1|AAH36797.1| 387|Homo sapiens ADRBK2 protein protein. 95 5e-19
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 95 5e-19
AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, recep... 95 5e-19
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 95 5e-19
X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2 ... 95 6e-19
L00727-6|AAA75240.1| 540|Homo sapiens myotonin-protein kinase, ... 94 8e-19
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 94 1e-18
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 94 1e-18
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 94 1e-18
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 93 2e-18
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 2e-18
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 2e-18
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 93 2e-18
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 93 2e-18
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 2e-18
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 2e-18
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 93 2e-18
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 93 2e-18
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 93 2e-18
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 93 2e-18
AY874862-1|AAX59898.1| 424|Homo sapiens SH3-binding kinase prot... 92 3e-18
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 91 6e-18
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 91 6e-18
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 91 7e-18
AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein. 91 1e-17
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 91 1e-17
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 90 1e-17
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 90 1e-17
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 90 1e-17
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 90 1e-17
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 90 1e-17
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 90 1e-17
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 90 2e-17
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 89 3e-17
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 89 3e-17
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 89 3e-17
BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein. 89 3e-17
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 89 3e-17
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 89 3e-17
U00686-1|AAA03565.1| 544|Homo sapiens putative novel receptor k... 89 4e-17
L16862-1|AAA60175.1| 576|Homo sapiens G protein-coupled recepto... 89 4e-17
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 89 4e-17
BC017272-1|AAH17272.1| 589|Homo sapiens G protein-coupled recep... 89 4e-17
BC009277-1|AAH09277.1| 576|Homo sapiens G protein-coupled recep... 89 4e-17
AL022069-1|CAI19650.1| 166|Homo sapiens ribosomal protein S6 ki... 89 4e-17
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 89 4e-17
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 89 4e-17
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 89 4e-17
AF040752-1|AAC09274.1| 560|Homo sapiens G protein-coupled recep... 89 4e-17
AF040751-1|AAC09273.1| 589|Homo sapiens G protein-coupled recep... 89 4e-17
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 89 4e-17
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 89 4e-17
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 88 7e-17
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 88 7e-17
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 88 7e-17
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 88 7e-17
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 88 7e-17
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 88 7e-17
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 87 9e-17
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 87 9e-17
AL450063-4|CAI16847.1| 175|Homo sapiens protein kinase, cAMP-de... 87 9e-17
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 87 9e-17
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 87 9e-17
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 87 1e-16
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 87 1e-16
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 87 1e-16
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 87 1e-16
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 87 1e-16
AY358353-1|AAQ88719.1| 364|Homo sapiens HSA250839 protein. 87 2e-16
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 86 2e-16
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 86 2e-16
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 86 3e-16
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 86 3e-16
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 86 3e-16
U33168-4|AAC50412.1| 500|Homo sapiens G protein-coupled recepto... 85 4e-16
U33168-3|AAC50409.1| 546|Homo sapiens G protein-coupled recepto... 85 4e-16
U33168-2|AAC50411.1| 532|Homo sapiens G protein-coupled recepto... 85 4e-16
U33168-1|AAC50410.1| 578|Homo sapiens G protein-coupled recepto... 85 4e-16
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 85 5e-16
X98118-1|CAA66802.1| 532|Homo sapiens G protein-coupled recepto... 85 5e-16
X97881-1|CAA66470.1| 578|Homo sapiens G-protein coupled recepto... 85 5e-16
X97880-1|CAA66469.1| 546|Homo sapiens G-protein coupled recepto... 85 5e-16
X97879-1|CAA66468.1| 500|Homo sapiens G-protein coupled recepto... 85 5e-16
U33056-1|AAC50408.1| 532|Homo sapiens G protein-coupled recepto... 85 5e-16
U33055-1|AAC50407.1| 546|Homo sapiens G protein-coupled recepto... 85 5e-16
U33054-1|AAC50406.1| 578|Homo sapiens G protein-coupled recepto... 85 5e-16
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 85 5e-16
L03718-1|AAB04045.1| 500|Homo sapiens G protein-coupled recepto... 85 5e-16
BC117320-1|AAI17321.1| 578|Homo sapiens G protein-coupled recep... 85 5e-16
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 85 5e-16
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 85 5e-16
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 85 5e-16
AK223581-1|BAD97301.1| 500|Homo sapiens G protein-coupled recep... 85 5e-16
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 85 5e-16
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 85 5e-16
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 85 5e-16
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 85 5e-16
L15388-1|AAA58620.1| 590|Homo sapiens G protein-coupled recepto... 85 6e-16
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 85 6e-16
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 85 6e-16
BC064506-1|AAH64506.1| 590|Homo sapiens G protein-coupled recep... 85 6e-16
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 85 6e-16
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 85 6e-16
AL583824-2|CAI16759.1| 590|Homo sapiens G protein-coupled recep... 85 6e-16
AL355861-4|CAI15804.1| 590|Homo sapiens G protein-coupled recep... 85 6e-16
AL355273-2|CAI16487.1| 590|Homo sapiens G protein-coupled recep... 85 6e-16
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 85 6e-16
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 85 6e-16
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 85 6e-16
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 85 6e-16
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 85 6e-16
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 84 9e-16
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 84 9e-16
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 84 9e-16
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 84 9e-16
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 84 9e-16
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 84 9e-16
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 84 1e-15
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 83 1e-15
>AK057735-1|BAB71555.1| 274|Homo sapiens protein ( Homo sapiens
cDNA FLJ25006 fis, clone CBL00989. ).
Length = 274
Score = 154 bits (374), Expect = 5e-37
Identities = 75/190 (39%), Positives = 116/190 (61%)
Frame = +1
Query: 394 WPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAK 573
WPV ++FLPEFPI+ Q+ +I +AKG+FG V KV ++ +A+KV+ K K
Sbjct: 83 WPVPQFINLFLPEFPIRPIRGQQQLKILGLVAKGSFGTVLKVLDCTQKAVFAVKVVPKVK 142
Query: 574 IVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGK 753
++ + VRQ KEE IQ +H F+ WQ K+ ++I+ Y +L L G
Sbjct: 143 VLQRDTVRQCKEEVSIQRQI-NHPFVHSLGDSWQGKRHLFIMCSYC-STDLYSLWSAVGC 200
Query: 754 LPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRT 933
PE +++F AE+ + + +LH+ G+++RD+K ENILLD H++L DFGLS+ + G++
Sbjct: 201 FPEASIRLFAAELVLVLCYLHDLGIMHRDVKMENILLDERGHLKLTDFGLSRHVPQGAQA 260
Query: 934 TTLCGTLNYM 963
T+CGTL YM
Sbjct: 261 YTICGTLQYM 270
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 140 bits (340), Expect = 7e-33
Identities = 66/175 (37%), Positives = 112/175 (64%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E + +
Sbjct: 243 QDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN 302
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
H F+VG S +QT+ R++ V EY+ GG+L+ +++ KLPEE + + AEI++A+++LH
Sbjct: 303 HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHE 362
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLD+E HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 363 RGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILR 417
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 140 bits (340), Expect = 7e-33
Identities = 66/175 (37%), Positives = 112/175 (64%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E + +
Sbjct: 243 QDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN 302
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
H F+VG S +QT+ R++ V EY+ GG+L+ +++ KLPEE + + AEI++A+++LH
Sbjct: 303 HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHE 362
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLD+E HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 363 RGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILR 417
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 140 bits (340), Expect = 7e-33
Identities = 66/175 (37%), Positives = 112/175 (64%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E + +
Sbjct: 243 QDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN 302
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
H F+VG S +QT+ R++ V EY+ GG+L+ +++ KLPEE + + AEI++A+++LH
Sbjct: 303 HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHE 362
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLD+E HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 363 RGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILR 417
>Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta
protein.
Length = 584
Score = 139 bits (337), Expect = 2e-32
Identities = 67/175 (38%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 242 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 301
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 302 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 361
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 362 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 416
>BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 139 bits (337), Expect = 2e-32
Identities = 67/175 (38%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 424
>BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 139 bits (337), Expect = 2e-32
Identities = 67/175 (38%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 424
>BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 139 bits (337), Expect = 2e-32
Identities = 67/175 (38%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 424
>AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 139 bits (337), Expect = 2e-32
Identities = 67/175 (38%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 424
>AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 139 bits (337), Expect = 2e-32
Identities = 67/175 (38%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 424
>AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 139 bits (337), Expect = 2e-32
Identities = 67/175 (38%), Positives = 110/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G++ V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 424
>L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta
protein.
Length = 592
Score = 139 bits (336), Expect = 2e-32
Identities = 67/175 (38%), Positives = 109/175 (62%), Gaps = 1/175 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF + I +G + V V+ ++ YA+KV+ K + ++ + V+ E +
Sbjct: 250 QDFDLIRVIGRGTYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
+ F+VG S +QT R+++V EY+ GG+L+ +++ KLPEE + + AEI IA++FLH
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLDA+ HI+L D+G+ K L G T+T CGT NY+ ++R
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILR 424
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 137 bits (331), Expect = 9e-32
Identities = 68/174 (39%), Positives = 101/174 (58%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V K+ + K YA+KVL K ++N + + E + H
Sbjct: 94 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 153
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +++ GGEL +++ PE + + AEIA A+ +LH+
Sbjct: 154 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 213
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
++YRDLKPENILLD+ H+ L DFGL K ++I TTT CGT Y+ +IR
Sbjct: 214 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIR 267
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 137 bits (331), Expect = 9e-32
Identities = 68/174 (39%), Positives = 101/174 (58%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V K+ + K YA+KVL K ++N + + E + H
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +++ GGEL +++ PE + + AEIA A+ +LH+
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
++YRDLKPENILLD+ H+ L DFGL K ++I TTT CGT Y+ +IR
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIR 334
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 137 bits (331), Expect = 9e-32
Identities = 68/174 (39%), Positives = 101/174 (58%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V K+ + K YA+KVL K ++N + + E + H
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +++ GGEL +++ PE + + AEIA A+ +LH+
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
++YRDLKPENILLD+ H+ L DFGL K ++I TTT CGT Y+ +IR
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIR 334
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 137 bits (331), Expect = 9e-32
Identities = 68/174 (39%), Positives = 101/174 (58%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V K+ + K YA+KVL K ++N + + E + H
Sbjct: 94 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 153
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +++ GGEL +++ PE + + AEIA A+ +LH+
Sbjct: 154 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 213
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
++YRDLKPENILLD+ H+ L DFGL K ++I TTT CGT Y+ +IR
Sbjct: 214 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIR 267
>AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL
protein.
Length = 496
Score = 136 bits (329), Expect = 2e-31
Identities = 67/174 (38%), Positives = 101/174 (58%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V K+ + K YA+KVL K ++N + + E + H
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +++ GGEL +++ PE + + AEIA A+ +LH+
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
++YRDLKPENIL+D+ H+ L DFGL K ++I TTT CGT Y+ +IR
Sbjct: 281 KIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIR 334
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 136 bits (328), Expect = 2e-31
Identities = 81/206 (39%), Positives = 118/206 (57%), Gaps = 8/206 (3%)
Frame = +1
Query: 397 PVAHKESIFLPEFPIKTD---LLQKDFQIQHTIAKGAFGDVYKVKKVSEN--KEYALKVL 561
PV H E + L E + + F++ + KG +G V++V+KV N K YA+KVL
Sbjct: 41 PVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGNLGKIYAMKVL 100
Query: 562 SKAKIV-NENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLI 738
KAKIV N + E I + H FIV +QT ++Y++ E + GGEL +
Sbjct: 101 RKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTHL 159
Query: 739 EKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WL 915
E+ G E+ ++AEI +A+ LH+ G+IYRDLKPENI+L ++ HI+L DFGL K +
Sbjct: 160 EREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESI 219
Query: 916 SIGSRTTTLCGTLNYMVWN-LIRSNY 990
G+ T T CGT+ YM L+RS +
Sbjct: 220 HEGAVTHTFCGTIEYMAPEILVRSGH 245
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 125
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 994 WQSA 1005
QSA
Sbjct: 246 TQSA 249
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 535 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase 3
protein.
Length = 580
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 67 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 124
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 125 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 184
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 185 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 244
Query: 994 WQSA 1005
QSA
Sbjct: 245 TQSA 248
Score = 65.3 bits (152), Expect = 4e-10
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 421 YELKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 473
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+ + GGELL I + E + I +++LH G
Sbjct: 474 NIITLNDVYDDGKYVYVVT-LMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 532
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL 915
V++RDLKP NIL E I++ DFG +K L
Sbjct: 533 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQL 566
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 125
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 994 WQSA 1005
QSA
Sbjct: 246 TQSA 249
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 535 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 125
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 994 WQSA 1005
QSA
Sbjct: 246 TQSA 249
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 535 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 134 bits (323), Expect = 8e-31
Identities = 80/207 (38%), Positives = 117/207 (56%), Gaps = 9/207 (4%)
Frame = +1
Query: 397 PVAHKESIFLPEFPIKTD---LLQKDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKV 558
PV H E + L E + + F++ + KG +G V++V+KV K YA+KV
Sbjct: 41 PVGHYEEVELTETSVNVGPERIGPHSFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKV 100
Query: 559 LSKAKIV-NENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGL 735
L KAKIV N + E I + H FIV +QT ++Y++ E + GGEL
Sbjct: 101 LRKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTH 159
Query: 736 IEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-W 912
+E+ G E+ ++AEI +A+ LH+ G+IYRDLKPENI+L ++ HI+L DFGL K
Sbjct: 160 LEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKES 219
Query: 913 LSIGSRTTTLCGTLNYMVWN-LIRSNY 990
+ G+ T T CGT+ YM L+RS +
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH 246
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 125
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 994 WQSA 1005
QSA
Sbjct: 246 TQSA 249
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 535 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
>AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 227
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 39 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 96
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 97 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 156
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 157 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 216
Query: 994 WQSA 1005
QSA
Sbjct: 217 TQSA 220
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 125
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 994 WQSA 1005
QSA
Sbjct: 246 TQSA 249
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 535 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 variant protein.
Length = 806
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 135 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 192
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 193 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 252
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 253 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 312
Query: 994 WQSA 1005
QSA
Sbjct: 313 TQSA 316
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 488 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 540
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 541 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 600
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 601 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 657
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 134 bits (323), Expect = 8e-31
Identities = 75/184 (40%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+S + YA+KVL KA + + VR K E I
Sbjct: 54 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 111
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 112 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 171
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 172 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 231
Query: 994 WQSA 1005
QSA
Sbjct: 232 TQSA 235
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 408 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 460
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 461 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 520
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 521 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 577
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 133 bits (321), Expect = 1e-30
Identities = 75/184 (40%), Positives = 114/184 (61%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKV--SENKE-YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ VKK+ S+ ++ YA+KVL KA + + VR K E I
Sbjct: 68 FELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEV- 125
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 994 WQSA 1005
QSA
Sbjct: 246 TQSA 249
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH G
Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L + T C T N++ +++
Sbjct: 535 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 132 bits (320), Expect = 2e-30
Identities = 80/207 (38%), Positives = 117/207 (56%), Gaps = 9/207 (4%)
Frame = +1
Query: 397 PVAHKESIFLPEFPIKTD---LLQKDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKV 558
PV H E + L E + + F++ + KG +G V++V+KV K YA+KV
Sbjct: 41 PVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKV 100
Query: 559 LSKAKIV-NENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGL 735
L KAKIV N + E I + H FIV +QT ++Y++ E + GGEL
Sbjct: 101 LRKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTH 159
Query: 736 IEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-W 912
+E+ G E+ ++AEI +A+ LH+ G+IYRDLKPENI+L ++ HI+L DFGL K
Sbjct: 160 LEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKES 219
Query: 913 LSIGSRTTTLCGTLNYMVWN-LIRSNY 990
+ G+ T T CGT+ YM L+RS +
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH 246
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 132 bits (320), Expect = 2e-30
Identities = 80/207 (38%), Positives = 117/207 (56%), Gaps = 9/207 (4%)
Frame = +1
Query: 397 PVAHKESIFLPEFPIKTD---LLQKDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKV 558
PV H E + L E + + F++ + KG +G V++V+KV K YA+KV
Sbjct: 41 PVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKV 100
Query: 559 LSKAKIV-NENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGL 735
L KAKIV N + E I + H FIV +QT ++Y++ E + GGEL
Sbjct: 101 LRKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTH 159
Query: 736 IEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-W 912
+E+ G E+ ++AEI +A+ LH+ G+IYRDLKPENI+L ++ HI+L DFGL K
Sbjct: 160 LEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKES 219
Query: 913 LSIGSRTTTLCGTLNYMVWN-LIRSNY 990
+ G+ T T CGT+ YM L+RS +
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH 246
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 132 bits (320), Expect = 2e-30
Identities = 80/207 (38%), Positives = 117/207 (56%), Gaps = 9/207 (4%)
Frame = +1
Query: 397 PVAHKESIFLPEFPIKTD---LLQKDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKV 558
PV H E + L E + + F++ + KG +G V++V+KV K YA+KV
Sbjct: 41 PVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKV 100
Query: 559 LSKAKIV-NENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGL 735
L KAKIV N + E I + H FIV +QT ++Y++ E + GGEL
Sbjct: 101 LRKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTH 159
Query: 736 IEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-W 912
+E+ G E+ ++AEI +A+ LH+ G+IYRDLKPENI+L ++ HI+L DFGL K
Sbjct: 160 LEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKES 219
Query: 913 LSIGSRTTTLCGTLNYMVWN-LIRSNY 990
+ G+ T T CGT+ YM L+RS +
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH 246
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 132 bits (320), Expect = 2e-30
Identities = 80/207 (38%), Positives = 117/207 (56%), Gaps = 9/207 (4%)
Frame = +1
Query: 397 PVAHKESIFLPEFPIKTD---LLQKDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKV 558
PV H E + L E + + F++ + KG +G V++V+KV K YA+KV
Sbjct: 54 PVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKV 113
Query: 559 LSKAKIV-NENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGL 735
L KAKIV N + E I + H FIV +QT ++Y++ E + GGEL
Sbjct: 114 LRKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTH 172
Query: 736 IEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-W 912
+E+ G E+ ++AEI +A+ LH+ G+IYRDLKPENI+L ++ HI+L DFGL K
Sbjct: 173 LEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKES 232
Query: 913 LSIGSRTTTLCGTLNYMVWN-LIRSNY 990
+ G+ T T CGT+ YM L+RS +
Sbjct: 233 IHEGAVTHTFCGTIEYMAPEILVRSGH 259
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 131 bits (317), Expect = 4e-30
Identities = 71/184 (38%), Positives = 110/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G++G V+ V+KV + YA+KVL KA + + VR E +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-- 116
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI++ DFGLSK + R + CGT+ YM ++
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 236
Query: 994 WQSA 1005
QSA
Sbjct: 237 TQSA 240
Score = 79.0 bits (186), Expect = 3e-14
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++I+ I G++ + + + EYA+K++ K+K R EE +I G H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V E + GGELL I + E + I +D+LH+ G
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 527
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWLSIGS-RTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L G+ T C T N++ +++
Sbjct: 528 VVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLK 584
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 131 bits (317), Expect = 4e-30
Identities = 71/184 (38%), Positives = 110/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G++G V+ V+KV + YA+KVL KA + + VR E +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-- 116
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI++ DFGLSK + R + CGT+ YM ++
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 236
Query: 994 WQSA 1005
QSA
Sbjct: 237 TQSA 240
Score = 79.0 bits (186), Expect = 3e-14
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++I+ I G++ + + + EYA+K++ K+K R EE +I G H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V E + GGELL I + E + I +D+LH+ G
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 527
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWLSIGS-RTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L G+ T C T N++ +++
Sbjct: 528 VVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLK 584
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase 2
protein.
Length = 540
Score = 131 bits (317), Expect = 4e-30
Identities = 71/184 (38%), Positives = 110/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G++G V+ V+KV + YA+KVL KA + + VR E +
Sbjct: 60 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-- 117
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 118 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 177
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI++ DFGLSK + R + CGT+ YM ++
Sbjct: 178 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 237
Query: 994 WQSA 1005
QSA
Sbjct: 238 TQSA 241
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/132 (31%), Positives = 66/132 (50%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++I+ I G++ + + + EYA+K++ K+K R EE +I G H
Sbjct: 416 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIGKSK-------RDPSEEIEILLRYGQHP 468
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V E + GGELL I + E + I +D+LH+ G
Sbjct: 469 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 528
Query: 826 VIYRDLKPENIL 861
V++RDLKP NIL
Sbjct: 529 VVHRDLKPSNIL 540
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 131 bits (317), Expect = 4e-30
Identities = 71/184 (38%), Positives = 110/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G++G V+ V+KV + YA+KVL KA + + VR E +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-- 116
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI++ DFGLSK + R + CGT+ YM ++
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 236
Query: 994 WQSA 1005
QSA
Sbjct: 237 TQSA 240
Score = 79.0 bits (186), Expect = 3e-14
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++I+ I G++ + + + EYA+K++ K+K R EE +I G H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V E + GGELL I + E + I +D+LH+ G
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 527
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWLSIGS-RTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L G+ T C T N++ +++
Sbjct: 528 VVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLK 584
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 131 bits (317), Expect = 4e-30
Identities = 71/184 (38%), Positives = 110/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G++G V+ V+KV + YA+KVL KA + + VR E +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-- 116
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI++ DFGLSK + R + CGT+ YM ++
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 236
Query: 994 WQSA 1005
QSA
Sbjct: 237 TQSA 240
Score = 79.0 bits (186), Expect = 3e-14
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++I+ I G++ + + + EYA+K++ K+K R EE +I G H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V E + GGELL I + E + I +D+LH+ G
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 527
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWLSIGS-RTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L G+ T C T N++ +++
Sbjct: 528 VVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLK 584
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 131 bits (317), Expect = 4e-30
Identities = 71/184 (38%), Positives = 110/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G++G V+ V+KV + YA+KVL KA + + VR E +
Sbjct: 132 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-- 189
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+A+D LH
Sbjct: 190 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 249
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
+ G+IYRDLKPENILLD E HI++ DFGLSK + R + CGT+ YM ++
Sbjct: 250 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 309
Query: 994 WQSA 1005
QSA
Sbjct: 310 TQSA 313
Score = 79.0 bits (186), Expect = 3e-14
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 5/177 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++I+ I G++ + + + EYA+K++ K+K R EE +I G H
Sbjct: 488 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 540
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V E + GGELL I + E + I +D+LH+ G
Sbjct: 541 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 600
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWLSIGS-RTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL E I++ DFG +K L G+ T C T N++ +++
Sbjct: 601 VVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLK 657
>M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase
alpha-II protein.
Length = 502
Score = 130 bits (315), Expect = 8e-30
Identities = 73/181 (40%), Positives = 109/181 (60%), Gaps = 6/181 (3%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVS---ENKEYALKVLSKAKIV-NENAVRQVKEEAKIQTAC 633
F++ + KG +G V++V+KV+ K +A+KVL KA IV N K E I
Sbjct: 68 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 127
Query: 634 GHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFL 813
H FIV + +QT ++Y++ EY+ GGEL +E+ G E+ ++AEI++A+ L
Sbjct: 128 -KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHL 186
Query: 814 HNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWN-LIRSN 987
H G+IYRDLKPENI+L+ + H++L DFGL K + G+ T T CGT+ YM L+RS
Sbjct: 187 HQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSG 246
Query: 988 Y 990
+
Sbjct: 247 H 247
>M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase
alpha-I protein.
Length = 525
Score = 130 bits (315), Expect = 8e-30
Identities = 73/181 (40%), Positives = 109/181 (60%), Gaps = 6/181 (3%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVS---ENKEYALKVLSKAKIV-NENAVRQVKEEAKIQTAC 633
F++ + KG +G V++V+KV+ K +A+KVL KA IV N K E I
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 634 GHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFL 813
H FIV + +QT ++Y++ EY+ GGEL +E+ G E+ ++AEI++A+ L
Sbjct: 151 -KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHL 209
Query: 814 HNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWN-LIRSN 987
H G+IYRDLKPENI+L+ + H++L DFGL K + G+ T T CGT+ YM L+RS
Sbjct: 210 HQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSG 269
Query: 988 Y 990
+
Sbjct: 270 H 270
>BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein.
Length = 451
Score = 130 bits (315), Expect = 8e-30
Identities = 73/181 (40%), Positives = 109/181 (60%), Gaps = 6/181 (3%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVS---ENKEYALKVLSKAKIV-NENAVRQVKEEAKIQTAC 633
F++ + KG +G V++V+KV+ K +A+KVL KA IV N K E I
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 634 GHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFL 813
H FIV + +QT ++Y++ EY+ GGEL +E+ G E+ ++AEI++A+ L
Sbjct: 151 -KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHL 209
Query: 814 HNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWN-LIRSN 987
H G+IYRDLKPENI+L+ + H++L DFGL K + G+ T T CGT+ YM L+RS
Sbjct: 210 HQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSG 269
Query: 988 Y 990
+
Sbjct: 270 H 270
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 130 bits (314), Expect = 1e-29
Identities = 70/214 (32%), Positives = 117/214 (54%), Gaps = 2/214 (0%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEF--PIKTDLLQKDFQIQHTIAKGAFGDVYKVK 522
N +T K E +A + FL ++ P + + +DF+ + T+ G+FG V VK
Sbjct: 3 NAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVK 62
Query: 523 KVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVS 702
+ + YA+K+L K K+V + E +I A + F+V ++ +Y+V
Sbjct: 63 HKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-NFPFLVRLEYAFKDNSNLYMVM 121
Query: 703 EYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHI 882
EY+PGGE+ + + G+ E + + A+I + ++LH+ +IYRDLKPEN+L+D + +I
Sbjct: 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYI 181
Query: 883 QLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
Q+ DFG +K + RT TLCGT Y+ +I S
Sbjct: 182 QVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILS 213
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 130 bits (314), Expect = 1e-29
Identities = 66/174 (37%), Positives = 98/174 (56%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AID+LH+
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIDYLHSL 153
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 207
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 130 bits (314), Expect = 1e-29
Identities = 70/214 (32%), Positives = 117/214 (54%), Gaps = 2/214 (0%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEF--PIKTDLLQKDFQIQHTIAKGAFGDVYKVK 522
N +T K E +A + FL ++ P + + +DF+ + T+ G+FG V VK
Sbjct: 3 NAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVK 62
Query: 523 KVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVS 702
+ + YA+K+L K K+V + E +I A + F+V ++ +Y+V
Sbjct: 63 HKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-NFPFLVRLEYAFKDNSNLYMVM 121
Query: 703 EYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHI 882
EY+PGGE+ + + G+ E + + A+I + ++LH+ +IYRDLKPEN+L+D + +I
Sbjct: 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYI 181
Query: 883 QLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
Q+ DFG +K + RT TLCGT Y+ +I S
Sbjct: 182 QVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILS 213
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 130 bits (314), Expect = 1e-29
Identities = 70/214 (32%), Positives = 117/214 (54%), Gaps = 2/214 (0%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEF--PIKTDLLQKDFQIQHTIAKGAFGDVYKVK 522
N +T K E +A + FL ++ P + + +DF+ + T+ G+FG V VK
Sbjct: 3 NAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVK 62
Query: 523 KVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVS 702
+ + YA+K+L K K+V + E +I A + F+V ++ +Y+V
Sbjct: 63 HKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-NFPFLVRLEYAFKDNSNLYMVM 121
Query: 703 EYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHI 882
EY+PGGE+ + + G+ E + + A+I + ++LH+ +IYRDLKPEN+L+D + +I
Sbjct: 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYI 181
Query: 883 QLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
Q+ DFG +K + RT TLCGT Y+ +I S
Sbjct: 182 QVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILS 213
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 130 bits (314), Expect = 1e-29
Identities = 70/214 (32%), Positives = 117/214 (54%), Gaps = 2/214 (0%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEF--PIKTDLLQKDFQIQHTIAKGAFGDVYKVK 522
N +T K E +A + FL ++ P + + +DF+ + T+ G+FG V VK
Sbjct: 3 NAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVK 62
Query: 523 KVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVS 702
+ + YA+K+L K K+V + E +I A + F+V ++ +Y+V
Sbjct: 63 HKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-NFPFLVRLEYAFKDNSNLYMVM 121
Query: 703 EYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHI 882
EY+PGGE+ + + G+ E + + A+I + ++LH+ +IYRDLKPEN+L+D + +I
Sbjct: 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYI 181
Query: 883 QLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
Q+ DFG +K + RT TLCGT Y+ +I S
Sbjct: 182 QVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILS 213
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 130 bits (314), Expect = 1e-29
Identities = 70/214 (32%), Positives = 117/214 (54%), Gaps = 2/214 (0%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEF--PIKTDLLQKDFQIQHTIAKGAFGDVYKVK 522
N +T K E +A + FL ++ P + + +DF+ + T+ G+FG V VK
Sbjct: 3 NAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVK 62
Query: 523 KVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVS 702
+ + YA+K+L K K+V + E +I A + F+V ++ +Y+V
Sbjct: 63 HKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-NFPFLVRLEYAFKDNSNLYMVM 121
Query: 703 EYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHI 882
EY+PGGE+ + + G+ E + + A+I + ++LH+ +IYRDLKPEN+L+D + +I
Sbjct: 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYI 181
Query: 883 QLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
Q+ DFG +K + RT TLCGT Y+ +I S
Sbjct: 182 QVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILS 213
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 130 bits (314), Expect = 1e-29
Identities = 70/214 (32%), Positives = 117/214 (54%), Gaps = 2/214 (0%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEF--PIKTDLLQKDFQIQHTIAKGAFGDVYKVK 522
N +T K E +A + FL ++ P + + +DF+ + T+ G+FG V VK
Sbjct: 3 NAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVK 62
Query: 523 KVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVS 702
+ + YA+K+L K K+V + E +I A + F+V ++ +Y+V
Sbjct: 63 HKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-NFPFLVRLEYAFKDNSNLYMVM 121
Query: 703 EYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHI 882
EY+PGGE+ + + G+ E + + A+I + ++LH+ +IYRDLKPEN+L+D + +I
Sbjct: 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYI 181
Query: 883 QLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
Q+ DFG +K + RT TLCGT Y+ +I S
Sbjct: 182 QVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILS 213
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 128 bits (310), Expect = 3e-29
Identities = 64/185 (34%), Positives = 106/185 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 79 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 138
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 139 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 197
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 198 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 255
Query: 970 NLIRS 984
+I S
Sbjct: 256 EIILS 260
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 128 bits (310), Expect = 3e-29
Identities = 64/185 (34%), Positives = 106/185 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 38 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 97
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 98 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 156
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 157 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 214
Query: 970 NLIRS 984
+I S
Sbjct: 215 EIILS 219
>AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 209
Score = 128 bits (310), Expect = 3e-29
Identities = 64/185 (34%), Positives = 106/185 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 27 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 86
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 87 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 145
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 146 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 203
Query: 970 NLIRS 984
+I S
Sbjct: 204 EIILS 208
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 128 bits (310), Expect = 3e-29
Identities = 64/185 (34%), Positives = 106/185 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 20 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 79
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 80 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 138
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 139 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 196
Query: 970 NLIRS 984
+I S
Sbjct: 197 EIILS 201
>AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 214
Score = 128 bits (310), Expect = 3e-29
Identities = 64/185 (34%), Positives = 106/185 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 28 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 87
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 88 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 146
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 147 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 204
Query: 970 NLIRS 984
+I S
Sbjct: 205 EIILS 209
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 128 bits (310), Expect = 3e-29
Identities = 64/185 (34%), Positives = 106/185 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 79 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 138
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 139 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 197
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 198 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 255
Query: 970 NLIRS 984
+I S
Sbjct: 256 EIILS 260
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 128 bits (310), Expect = 3e-29
Identities = 64/185 (34%), Positives = 106/185 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 58 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 117
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 118 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 176
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 177 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 234
Query: 970 NLIRS 984
+I S
Sbjct: 235 EIILS 239
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase 1
protein.
Length = 735
Score = 128 bits (309), Expect = 4e-29
Identities = 77/201 (38%), Positives = 117/201 (58%), Gaps = 9/201 (4%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ V+KV+ YA+KVL KA + + VR K E I A
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVR-TKMERDI-LADV 119
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H F+V +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+ +D LH
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI-RSNY 990
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++ R +
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239
Query: 991 K----WQSASVAPXAXLYGSV 1041
W S V L GS+
Sbjct: 240 SHSADWWSYGVLMFEMLTGSL 260
Score = 82.6 bits (195), Expect = 3e-15
Identities = 53/178 (29%), Positives = 90/178 (50%), Gaps = 6/178 (3%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
+ ++ TI G++ + + + N EYA+KV+ K+K R EE +I G H
Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHP 470
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH+ G
Sbjct: 471 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQG 530
Query: 826 VIYRDLKPENILL-----DAECHIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL + EC +++ DFG +K L + T C T N++ +++
Sbjct: 531 VVHRDLKPSNILYVDESGNPEC-LRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 587
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 128 bits (309), Expect = 4e-29
Identities = 69/214 (32%), Positives = 117/214 (54%), Gaps = 2/214 (0%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEF--PIKTDLLQKDFQIQHTIAKGAFGDVYKVK 522
N +T K E +A + FL ++ P + + +DF+ + T+ G+FG V VK
Sbjct: 3 NAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVK 62
Query: 523 KVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVS 702
+ + YA+K+L K K+V + E +I A + F+V ++ +Y+V
Sbjct: 63 HKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-NFPFLVRLEYAFKDNSNLYMVM 121
Query: 703 EYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHI 882
EY+PGGE+ + + G+ E + + A+I + ++L++ +IYRDLKPEN+L+D + +I
Sbjct: 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLNSLDIIYRDLKPENLLIDHQGYI 181
Query: 883 QLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
Q+ DFG +K + RT TLCGT Y+ +I S
Sbjct: 182 QVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILS 213
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 1 protein.
Length = 735
Score = 128 bits (309), Expect = 4e-29
Identities = 77/201 (38%), Positives = 117/201 (58%), Gaps = 9/201 (4%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ V+KV+ YA+KVL KA + + VR K E I A
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVR-TKMERDI-LADV 119
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H F+V +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+ +D LH
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI-RSNY 990
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++ R +
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239
Query: 991 K----WQSASVAPXAXLYGSV 1041
W S V L GS+
Sbjct: 240 SHSADWWSYGVLMFEMLTGSL 260
Score = 82.6 bits (195), Expect = 3e-15
Identities = 53/178 (29%), Positives = 90/178 (50%), Gaps = 6/178 (3%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
+ ++ TI G++ + + + N EYA+KV+ K+K R EE +I G H
Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHP 470
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH+ G
Sbjct: 471 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQG 530
Query: 826 VIYRDLKPENILL-----DAECHIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL + EC +++ DFG +K L + T C T N++ +++
Sbjct: 531 VVHRDLKPSNILYVDESGNPEC-LRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 587
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 1 protein.
Length = 735
Score = 128 bits (309), Expect = 4e-29
Identities = 77/201 (38%), Positives = 117/201 (58%), Gaps = 9/201 (4%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKE---YALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ V+KV+ YA+KVL KA + + VR K E I A
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVR-TKMERDI-LADV 119
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H F+V +QT+ ++Y++ +++ GG+L + K EE VK ++AE+A+ +D LH
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI-RSNY 990
+ G+IYRDLKPENILLD E HI+L DFGLSK + + + CGT+ YM ++ R +
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239
Query: 991 K----WQSASVAPXAXLYGSV 1041
W S V L GS+
Sbjct: 240 SHSADWWSYGVLMFEMLTGSL 260
Score = 82.6 bits (195), Expect = 3e-15
Identities = 53/178 (29%), Positives = 90/178 (50%), Gaps = 6/178 (3%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
+ ++ TI G++ + + + N EYA+KV+ K+K R EE +I G H
Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHP 470
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + K +Y+V+E + GGELL I + E + I +++LH+ G
Sbjct: 471 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQG 530
Query: 826 VIYRDLKPENILL-----DAECHIQLIDFGLSKWL-SIGSRTTTLCGTLNYMVWNLIR 981
V++RDLKP NIL + EC +++ DFG +K L + T C T N++ +++
Sbjct: 531 VVHRDLKPSNILYVDESGNPEC-LRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 587
>Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 127 bits (307), Expect = 7e-29
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 207
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 127 bits (307), Expect = 7e-29
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 267
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 127 bits (307), Expect = 7e-29
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 207
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 127 bits (307), Expect = 7e-29
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 207
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 127 bits (307), Expect = 7e-29
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 267
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 127 bits (307), Expect = 7e-29
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 207
>AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 197
Score = 127 bits (306), Expect = 9e-29
Identities = 62/178 (34%), Positives = 103/178 (57%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 19 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 78
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 79 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 137
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYM 963
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 138 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTPEYL 193
>X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein.
Length = 358
Score = 126 bits (305), Expect = 1e-28
Identities = 69/186 (37%), Positives = 104/186 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
PE P+ + LQ DF T+ G FG V+ VK+ + +ALKV+S ++ + V
Sbjct: 39 PEPPVYS--LQ-DFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVH 95
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E + H F++ W ++ +Y++ EY+PGGEL + G+ + A
Sbjct: 96 NEKSVLKEVSH-PFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSA 154
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMV 966
EI AI++LH+ ++YRDLKPENILLD + HI+L DFG +K + RT TLCGT Y+
Sbjct: 155 EIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAK--KLVDRTWTLCGTPEYLA 212
Query: 967 WNLIRS 984
+I+S
Sbjct: 213 PEVIQS 218
>BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linked
protein.
Length = 358
Score = 126 bits (305), Expect = 1e-28
Identities = 69/186 (37%), Positives = 104/186 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
PE P+ + LQ DF T+ G FG V+ VK+ + +ALKV+S ++ + V
Sbjct: 39 PEPPVYS--LQ-DFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVH 95
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E + H F++ W ++ +Y++ EY+PGGEL + G+ + A
Sbjct: 96 NEKSVLKEVSH-PFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSA 154
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMV 966
EI AI++LH+ ++YRDLKPENILLD + HI+L DFG +K + RT TLCGT Y+
Sbjct: 155 EIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAK--KLVDRTWTLCGTPEYLA 212
Query: 967 WNLIRS 984
+I+S
Sbjct: 213 PEVIQS 218
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 126 bits (305), Expect = 1e-28
Identities = 65/174 (37%), Positives = 96/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 60 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 119
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT + +Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 120 PFLVGLRYSFQTPEELYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 179
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 180 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 233
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 192 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 251
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 252 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 311
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 312 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 359
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 264
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 264
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 192 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 251
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 252 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 311
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 312 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 359
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 192 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 251
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 252 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 311
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 312 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 359
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 111 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 170
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 171 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 230
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 231 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 278
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 264
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 87 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 146
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 147 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 206
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 207 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 254
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 264
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 126 bits (304), Expect = 2e-28
Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG+FG V + +E YA+KVL K I+ + + + E + H
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT ++Y V +YI GGEL +++ E + + AEIA A+ +LH+
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYM 963
++YRDLKPENILLD++ HI L DFGL K + S T+T CGT Y+
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYL 264
>Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma
protein.
Length = 536
Score = 125 bits (301), Expect = 4e-28
Identities = 68/178 (38%), Positives = 103/178 (57%), Gaps = 6/178 (3%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI-----QT 627
DF + KG+FG V ++ ++ YA+K+L K IV ++ V E ++ +
Sbjct: 189 DFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRG 248
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
G F+ S +QT R+Y V EY+ GG+L+ I++ GK E + AEIAI +
Sbjct: 249 PGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLF 308
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
FLHN G+IYRDLK +N++LDAE HI++ DFG+ K + G+ T T CGT +Y+ +I
Sbjct: 309 FLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 366
>BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma
protein.
Length = 697
Score = 125 bits (301), Expect = 4e-28
Identities = 68/178 (38%), Positives = 103/178 (57%), Gaps = 6/178 (3%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI-----QT 627
DF + KG+FG V ++ ++ YA+K+L K IV ++ V E ++ +
Sbjct: 350 DFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRG 409
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
G F+ S +QT R+Y V EY+ GG+L+ I++ GK E + AEIAI +
Sbjct: 410 PGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLF 469
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
FLHN G+IYRDLK +N++LDAE HI++ DFG+ K + G+ T T CGT +Y+ +I
Sbjct: 470 FLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 527
>AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma
protein.
Length = 697
Score = 125 bits (301), Expect = 4e-28
Identities = 68/178 (38%), Positives = 103/178 (57%), Gaps = 6/178 (3%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI-----QT 627
DF + KG+FG V ++ ++ YA+K+L K IV ++ V E ++ +
Sbjct: 350 DFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRG 409
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
G F+ S +QT R+Y V EY+ GG+L+ I++ GK E + AEIAI +
Sbjct: 410 PGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLF 469
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
FLHN G+IYRDLK +N++LDAE HI++ DFG+ K + G+ T T CGT +Y+ +I
Sbjct: 470 FLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 527
>BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1797
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 502 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 561
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 562 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 668
>BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 140 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 199
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 200 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 258
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 259 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-MGLMSLTTNL 306
>BC009107-1|AAH09107.1| 879|Homo sapiens microtubule associated
serine/threonine kinase-like protein.
Length = 879
Score = 124 bits (300), Expect = 5e-28
Identities = 63/150 (42%), Positives = 96/150 (64%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
++F I I++GAFG VY +K K YA+KV+ KA ++N+N QV+ E + A
Sbjct: 33 EEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAE-RDALALSK 89
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
FIV Q+ +Y+V EY+ GG++ L+ YG EE+ +++E+A+A+D+LH
Sbjct: 90 SPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHR 149
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK 909
G+I+RDLKP+N+L+ E HI+L DFGLSK
Sbjct: 150 HGIIHRDLKPDNMLISNEGHIKLTDFGLSK 179
>BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 140 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 199
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 200 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 258
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 259 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-MGLMSLTTNL 306
>AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 387 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 446
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 447 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 505
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 506 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 553
>AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 502 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 561
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 562 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 668
>AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 387 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 446
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 447 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 505
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 506 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 553
>AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 502 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 561
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 562 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 668
>AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 502 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 561
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 562 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 668
>AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 206
Score = 124 bits (300), Expect = 5e-28
Identities = 61/174 (35%), Positives = 101/174 (58%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + + +DF+ + T+ G+FG V VK + + YA+K+L K K+V +
Sbjct: 35 ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN 94
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 95 EKRILQAV-NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 153
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGT 951
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT
Sbjct: 154 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGT 205
>AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 387 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 446
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 447 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 505
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 506 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 553
>AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 502 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 561
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 562 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-IGLMSLTTNL 668
>AL160291-7|CAI16908.1| 878|Homo sapiens novel protein kinase
domain containing protein protein.
Length = 878
Score = 124 bits (300), Expect = 5e-28
Identities = 63/150 (42%), Positives = 96/150 (64%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
++F I I++GAFG VY +K K YA+KV+ KA ++N+N QV+ E + A
Sbjct: 33 EEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAE-RDALALSK 89
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
FIV Q+ +Y+V EY+ GG++ L+ YG EE+ +++E+A+A+D+LH
Sbjct: 90 SPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHR 149
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK 909
G+I+RDLKP+N+L+ E HI+L DFGLSK
Sbjct: 150 HGIIHRDLKPDNMLISNEGHIKLTDFGLSK 179
>AL160291-6|CAI16909.1| 879|Homo sapiens novel protein kinase
domain containing protein protein.
Length = 879
Score = 124 bits (300), Expect = 5e-28
Identities = 63/150 (42%), Positives = 96/150 (64%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
++F I I++GAFG VY +K K YA+KV+ KA ++N+N QV+ E + A
Sbjct: 33 EEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAE-RDALALSK 89
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
FIV Q+ +Y+V EY+ GG++ L+ YG EE+ +++E+A+A+D+LH
Sbjct: 90 SPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHR 149
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK 909
G+I+RDLKP+N+L+ E HI+L DFGLSK
Sbjct: 150 HGIIHRDLKPDNMLISNEGHIKLTDFGLSK 179
>AL160291-5|CAI16910.1| 840|Homo sapiens novel protein kinase
domain containing protein protein.
Length = 840
Score = 124 bits (300), Expect = 5e-28
Identities = 63/150 (42%), Positives = 96/150 (64%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
++F I I++GAFG VY +K K YA+KV+ KA ++N+N QV+ E + A
Sbjct: 33 EEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAE-RDALALSK 89
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
FIV Q+ +Y+V EY+ GG++ L+ YG EE+ +++E+A+A+D+LH
Sbjct: 90 SPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHR 149
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK 909
G+I+RDLKP+N+L+ E HI+L DFGLSK
Sbjct: 150 HGIIHRDLKPDNMLISNEGHIKLTDFGLSK 179
>AK074804-1|BAC11218.1| 840|Homo sapiens protein ( Homo sapiens
cDNA FLJ90323 fis, clone NT2RP2001769, weakly similar to
SERINE/THREONINE-PROTEIN KINASE ORB6 (EC 2.7.1.-). ).
Length = 840
Score = 124 bits (300), Expect = 5e-28
Identities = 63/150 (42%), Positives = 96/150 (64%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
++F I I++GAFG VY +K K YA+KV+ KA ++N+N QV+ E + A
Sbjct: 33 EEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAE-RDALALSK 89
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
FIV Q+ +Y+V EY+ GG++ L+ YG EE+ +++E+A+A+D+LH
Sbjct: 90 SPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHR 149
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK 909
G+I+RDLKP+N+L+ E HI+L DFGLSK
Sbjct: 150 HGIIHRDLKPDNMLISNEGHIKLTDFGLSK 179
>AK027719-1|BAB55321.1| 878|Homo sapiens protein ( Homo sapiens
cDNA FLJ14813 fis, clone NT2RP4002408, moderately
similar to PROTEIN KINASE CEK1 (EC 2.7.1.-). ).
Length = 878
Score = 124 bits (300), Expect = 5e-28
Identities = 63/150 (42%), Positives = 96/150 (64%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
++F I I++GAFG VY +K K YA+KV+ KA ++N+N QV+ E + A
Sbjct: 33 EEFSIVKPISRGAFGKVYLGQK--GGKLYAVKVVKKADMINKNMTHQVQAE-RDALALSK 89
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
FIV Q+ +Y+V EY+ GG++ L+ YG EE+ +++E+A+A+D+LH
Sbjct: 90 SPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHR 149
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSK 909
G+I+RDLKP+N+L+ E HI+L DFGLSK
Sbjct: 150 HGIIHRDLKPDNMLISNEGHIKLTDFGLSK 179
>AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein.
Length = 1734
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 502 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 561
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 562 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-MGLMSLTTNL 668
>AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein.
Length = 1329
Score = 124 bits (300), Expect = 5e-28
Identities = 60/169 (35%), Positives = 105/169 (62%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P K ++DF+ I+ GA+G V+ V+ S + +A+K ++K ++ N ++Q E
Sbjct: 33 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVER 92
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
I T + F+V + TK+ + +V EY+ GG+ L++ G LP ++V+++ AE
Sbjct: 93 DILTFA-ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 151
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
+A+++LHN G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 152 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-MGLMSLTTNL 199
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 124 bits (299), Expect = 7e-28
Identities = 63/185 (34%), Positives = 100/185 (54%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + F+ T+ G+FG V VK YA+K+L K K+V +
Sbjct: 32 ESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN 91
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 92 EKRILQAV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 150
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 208
Query: 970 NLIRS 984
+I S
Sbjct: 209 EIILS 213
>M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha
protein.
Length = 207
Score = 124 bits (299), Expect = 7e-28
Identities = 63/185 (34%), Positives = 100/185 (54%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + F+ T+ G+FG V VK YA+K+L K K+V +
Sbjct: 15 ESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN 74
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 75 EKRILQAV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 133
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 134 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 191
Query: 970 NLIRS 984
+I S
Sbjct: 192 EIILS 196
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 124 bits (299), Expect = 7e-28
Identities = 63/185 (34%), Positives = 100/185 (54%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + F+ T+ G+FG V VK YA+K+L K K+V +
Sbjct: 32 ESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN 91
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 92 EKRILQAV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 150
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 208
Query: 970 NLIRS 984
+I S
Sbjct: 209 EIILS 213
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 124 bits (299), Expect = 7e-28
Identities = 63/185 (34%), Positives = 100/185 (54%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + F+ T+ G+FG V VK YA+K+L K K+V +
Sbjct: 32 ESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN 91
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 92 EKRILQAV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 150
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 208
Query: 970 NLIRS 984
+I S
Sbjct: 209 EIILS 213
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 124 bits (299), Expect = 7e-28
Identities = 63/185 (34%), Positives = 100/185 (54%)
Frame = +1
Query: 430 EFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKE 609
E P + F+ T+ G+FG V VK YA+K+L K K+V +
Sbjct: 32 ESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN 91
Query: 610 EAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAE 789
E +I A + F+V ++ +Y+V EY+PGGE+ + + G+ E + + A+
Sbjct: 92 EKRILQAV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 150
Query: 790 IAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVW 969
I + ++LH+ +IYRDLKPEN+L+D + +IQ+ DFG +K + RT TLCGT Y+
Sbjct: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 208
Query: 970 NLIRS 984
+I S
Sbjct: 209 EIILS 213
>Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 124 bits (298), Expect = 9e-28
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKE-SHIMAERSVLLKNVRH 92
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 93 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 152
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT Y+ ++R
Sbjct: 153 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 206
>AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha
variant protein.
Length = 461
Score = 124 bits (298), Expect = 9e-28
Identities = 63/173 (36%), Positives = 98/173 (56%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V + + YA+K+L K ++ ++ V E ++
Sbjct: 249 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 308
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ GK E +VAEI+I + FLH
Sbjct: 309 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYVAEISIGLFFLHKR 368
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 369 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 421
>BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 5 protein.
Length = 549
Score = 123 bits (297), Expect = 1e-27
Identities = 72/214 (33%), Positives = 116/214 (54%), Gaps = 13/214 (6%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNE-NAVRQVKEEAKIQT 627
++F++ + GA+G V+ V+K+S + K YA+KVL KA IV + + E ++
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT+ +++++ +YI GGEL + + + E V+I+V EI +A++
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG--SRTTTLCGTLNYMVWNLIR 981
LH G+IYRD+K ENILLD+ H+ L DFGLSK R + CGT+ YM +++R
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVR 226
Query: 982 SN-------YKWQSASVAPXAXLYGSVGWAVTGQ 1062
W S V L G+ + V G+
Sbjct: 227 GGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGE 260
Score = 54.8 bits (126), Expect = 6e-07
Identities = 33/123 (26%), Positives = 57/123 (46%)
Frame = +1
Query: 484 IAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAV 663
+ +G+F K N+ +A+K++SK N ++E C H IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEAN------TQKEITALKLCEGHPNIVKLH 485
Query: 664 SRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDL 843
+ + ++V E + GGEL I+K E + ++ A+ +H+ GV++RDL
Sbjct: 486 EVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDL 545
Query: 844 KPE 852
KPE
Sbjct: 546 KPE 548
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 6 protein.
Length = 745
Score = 123 bits (297), Expect = 1e-27
Identities = 70/184 (38%), Positives = 109/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVS---ENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ V+K + + YA+KVL KA + + VR K E I
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR-TKMERDILVEV- 130
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG++ + K EE VK ++AE+A+A+D LH
Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
G++YRDLKPENILLD HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGH 250
Query: 994 WQSA 1005
QSA
Sbjct: 251 SQSA 254
Score = 73.7 bits (173), Expect = 1e-12
Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 5/171 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + + +Y+V++ + GGELL I K E + I+ +D+LH G
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYM 963
V++RDLKP NIL E I++ DFG +K L T C T N++
Sbjct: 539 VVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFV 589
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 6 protein.
Length = 745
Score = 123 bits (297), Expect = 1e-27
Identities = 70/184 (38%), Positives = 109/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVS---ENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ V+K + + YA+KVL KA + + VR K E I
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR-TKMERDILVEV- 130
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG++ + K EE VK ++AE+A+A+D LH
Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
G++YRDLKPENILLD HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGH 250
Query: 994 WQSA 1005
QSA
Sbjct: 251 SQSA 254
Score = 73.7 bits (173), Expect = 1e-12
Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 5/171 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + + +Y+V++ + GGELL I K E + I+ +D+LH G
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYM 963
V++RDLKP NIL E I++ DFG +K L T C T N++
Sbjct: 539 VVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFV 589
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase protein.
Length = 745
Score = 123 bits (297), Expect = 1e-27
Identities = 70/184 (38%), Positives = 109/184 (59%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVS---ENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ V+K + + YA+KVL KA + + VR K E I
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR-TKMERDILVEV- 130
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG++ + K EE VK ++AE+A+A+D LH
Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
G++YRDLKPENILLD HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGH 250
Query: 994 WQSA 1005
QSA
Sbjct: 251 SQSA 254
Score = 73.7 bits (173), Expect = 1e-12
Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 5/171 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + + +Y+V++ + GGELL I K E + I+ +D+LH G
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYM 963
V++RDLKP NIL E I++ DFG +K L T C T N++
Sbjct: 539 VVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFV 589
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 123 bits (297), Expect = 1e-27
Identities = 72/214 (33%), Positives = 116/214 (54%), Gaps = 13/214 (6%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNE-NAVRQVKEEAKIQT 627
++F++ + GA+G V+ V+K+S + K YA+KVL KA IV + + E ++
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT+ +++++ +YI GGEL + + + E V+I+V EI +A++
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG--SRTTTLCGTLNYMVWNLIR 981
LH G+IYRD+K ENILLD+ H+ L DFGLSK R + CGT+ YM +++R
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVR 226
Query: 982 SN-------YKWQSASVAPXAXLYGSVGWAVTGQ 1062
W S V L G+ + V G+
Sbjct: 227 GGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGE 260
Score = 62.1 bits (144), Expect = 4e-09
Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 3/145 (2%)
Frame = +1
Query: 484 IAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAV 663
+ +G+F K N+ +K++SK N ++E C H IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQALQVKIISKRMEAN------TQKEITALKLCEGHPNIVKLH 485
Query: 664 SRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDL 843
+ + ++V E + GGEL + K E + ++ A+ +H+ GV++RDL
Sbjct: 486 EVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHRDL 545
Query: 844 KPENILLDAE---CHIQLIDFGLSK 909
KPEN+L E I++IDFG ++
Sbjct: 546 KPENLLFTDENDNLEIKIIDFGFAR 570
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase RLPK
protein.
Length = 802
Score = 123 bits (297), Expect = 1e-27
Identities = 72/214 (33%), Positives = 116/214 (54%), Gaps = 13/214 (6%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNE-NAVRQVKEEAKIQT 627
++F++ + GA+G V+ V+K+S + K YA+KVL KA IV + + E ++
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT+ +++++ +YI GGEL + + + E V+I+V EI +A++
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG--SRTTTLCGTLNYMVWNLIR 981
LH G+IYRD+K ENILLD+ H+ L DFGLSK R + CGT+ YM +++R
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVR 226
Query: 982 SN-------YKWQSASVAPXAXLYGSVGWAVTGQ 1062
W S V L G+ + V G+
Sbjct: 227 GGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGE 260
Score = 71.7 bits (168), Expect = 5e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 4/172 (2%)
Frame = +1
Query: 484 IAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAV 663
+ +G+F K N+ +A+K++SK N ++E C H IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEAN------TQKEITALKLCEGHPNIVKLH 485
Query: 664 SRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDL 843
+ + ++V E + GGEL I+K E + ++ A+ +H+ GV++RDL
Sbjct: 486 EVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDL 545
Query: 844 KPENILLDAE---CHIQLIDFGLSKWLSIGSR-TTTLCGTLNYMVWNLIRSN 987
KPEN+L E I++IDFG ++ ++ T C TL+Y L+ N
Sbjct: 546 KPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQN 597
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 123 bits (297), Expect = 1e-27
Identities = 72/214 (33%), Positives = 116/214 (54%), Gaps = 13/214 (6%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNE-NAVRQVKEEAKIQT 627
++F++ + GA+G V+ V+K+S + K YA+KVL KA IV + + E ++
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT+ +++++ +YI GGEL + + + E V+I+V EI +A++
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG--SRTTTLCGTLNYMVWNLIR 981
LH G+IYRD+K ENILLD+ H+ L DFGLSK R + CGT+ YM +++R
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVR 226
Query: 982 SN-------YKWQSASVAPXAXLYGSVGWAVTGQ 1062
W S V L G+ + V G+
Sbjct: 227 GGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGE 260
Score = 71.7 bits (168), Expect = 5e-12
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 4/172 (2%)
Frame = +1
Query: 484 IAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAV 663
+ +G+F K N+ +A+K++SK N ++E C H IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEAN------TQKEITALKLCEGHPNIVKLH 485
Query: 664 SRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDL 843
+ + ++V E + GGEL I+K E + ++ A+ +H+ GV++RDL
Sbjct: 486 EVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDL 545
Query: 844 KPENILLDAE---CHIQLIDFGLSKWLSIGSR-TTTLCGTLNYMVWNLIRSN 987
KPEN+L E I++IDFG ++ ++ T C TL+Y L+ N
Sbjct: 546 KPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQN 597
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 123 bits (296), Expect = 2e-27
Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A+++LH
Sbjct: 140 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + HIQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 259 ACKSSDL 265
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 123 bits (296), Expect = 2e-27
Identities = 65/174 (37%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
+F + KG+FG V + +++ YA+KVL K I+ ++ V E +I H
Sbjct: 407 EFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKH 466
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
++ +QTK R++ V EY+ GG+L+ I++ K E + + AE+ A+ FLH
Sbjct: 467 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH 526
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
GVIYRDLK +NILLDAE H +L DFG+ K + G TTT CGT +Y+ +++
Sbjct: 527 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQ 580
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 123 bits (296), Expect = 2e-27
Identities = 70/184 (38%), Positives = 108/184 (58%), Gaps = 4/184 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVS---ENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
F++ + +G+FG V+ V+K + + YA+KVL KA + VR K E I
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRGRVR-TKMERDILVEV- 130
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+H FIV +QT+ ++Y++ +++ GG++ + K EE VK ++AE+A+A+D LH
Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSNYK 993
G++YRDLKPENILLD HI+L DFGLSK + + + CGT+ YM ++
Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGH 250
Query: 994 WQSA 1005
QSA
Sbjct: 251 SQSA 254
Score = 73.7 bits (173), Expect = 1e-12
Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 5/171 (2%)
Frame = +1
Query: 466 FQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHS 645
++++ I G++ + + N E+A+K++ K+K R EE +I G H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 646 FIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAG 825
I+ + + +Y+V++ + GGELL I K E + I+ +D+LH G
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538
Query: 826 VIYRDLKPENILLDAEC----HIQLIDFGLSKWL-SIGSRTTTLCGTLNYM 963
V++RDLKP NIL E I++ DFG +K L T C T N++
Sbjct: 539 VVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFV 589
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 123 bits (296), Expect = 2e-27
Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A+++LH
Sbjct: 140 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + HIQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 259 ACKSSDL 265
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 123 bits (296), Expect = 2e-27
Identities = 65/174 (37%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
+F + KG+FG V + +++ YA+KVL K I+ ++ V E +I H
Sbjct: 407 EFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKH 466
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
++ +QTK R++ V EY+ GG+L+ I++ K E + + AE+ A+ FLH
Sbjct: 467 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH 526
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
GVIYRDLK +NILLDAE H +L DFG+ K + G TTT CGT +Y+ +++
Sbjct: 527 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQ 580
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 123 bits (296), Expect = 2e-27
Identities = 65/174 (37%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
+F + KG+FG V + +++ YA+KVL K I+ ++ V E +I H
Sbjct: 407 EFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKH 466
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
++ +QTK R++ V EY+ GG+L+ I++ K E + + AE+ A+ FLH
Sbjct: 467 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH 526
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
GVIYRDLK +NILLDAE H +L DFG+ K + G TTT CGT +Y+ +++
Sbjct: 527 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQ 580
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide dependent
protein kinase-1 protein.
Length = 556
Score = 123 bits (296), Expect = 2e-27
Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A+++LH
Sbjct: 140 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + HIQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 259 ACKSSDL 265
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide dependent
protein kinase-1 protein.
Length = 556
Score = 123 bits (296), Expect = 2e-27
Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A+++LH
Sbjct: 140 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + HIQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 259 ACKSSDL 265
>AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human
serine-threonine protein kinase R31240_1 protein.
Length = 1237
Score = 123 bits (296), Expect = 2e-27
Identities = 58/162 (35%), Positives = 101/162 (62%)
Frame = +1
Query: 457 QKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
+ DF I+ GA+G VY V+ + +A+K ++K ++ N ++Q E I T
Sbjct: 12 ENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFA- 70
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+ F+VG ++T++ + +V EY+ GG+ L++ G LP E+ +++ AE +A+++LH
Sbjct: 71 ENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLH 130
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
N G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 131 NYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-MGLMSLTTNL 171
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 123 bits (296), Expect = 2e-27
Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 72 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 131
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A+++LH
Sbjct: 132 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 190
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + HIQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 191 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 250
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 251 ACKSSDL 257
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide dependent
protein kinase-1 variant protein.
Length = 492
Score = 123 bits (296), Expect = 2e-27
Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 118 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 177
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A+++LH
Sbjct: 178 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 236
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + HIQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 237 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 296
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 297 ACKSSDL 303
>AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein.
Length = 1583
Score = 123 bits (296), Expect = 2e-27
Identities = 58/162 (35%), Positives = 101/162 (62%)
Frame = +1
Query: 457 QKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
+ DF I+ GA+G VY V+ + +A+K ++K ++ N ++Q E I T
Sbjct: 384 ENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFA- 442
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+ F+VG ++T++ + +V EY+ GG+ L++ G LP E+ +++ AE +A+++LH
Sbjct: 443 ENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLH 502
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
N G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 503 NYGIVHRDLKPDNLLITSMGHIKLTDFGLSK-MGLMSLTTNL 543
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 330 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 389
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 390 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 448
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 449 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 508
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 509 IGFGKKTWTFCGTPEYVAPEII 530
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 330 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 389
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 390 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 448
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 449 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 508
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 509 IGFGKKTWTFCGTPEYVAPEII 530
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 318 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 377
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 378 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 436
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 437 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 496
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 497 IGFGKKTWTFCGTPEYVAPEII 518
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 318 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 377
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 378 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 436
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 437 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 496
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 497 IGFGKKTWTFCGTPEYVAPEII 518
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 318 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 377
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 378 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 436
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 437 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 496
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 497 IGFGKKTWTFCGTPEYVAPEII 518
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 122 bits (295), Expect = 2e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 318 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 377
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 378 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 436
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 437 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 496
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 497 IGFGKKTWTFCGTPEYVAPEII 518
>Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 122 bits (294), Expect = 3e-27
Identities = 62/168 (36%), Positives = 94/168 (55%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ G FG V+ VK+ + +ALKV+S ++ + V E + H F++
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH-PFLIRL 112
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
W ++ +Y++ EY+PGGEL + G + AEI AI++LH+ ++YRD
Sbjct: 113 FWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRD 172
Query: 841 LKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
LKPENILLD + HI+L DFG +K + RT TLCGT Y+ +I+S
Sbjct: 173 LKPENILLDRDGHIKLTDFGFAK--KLVDRTWTLCGTPEYLAPEVIQS 218
>Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 122 bits (294), Expect = 3e-27
Identities = 62/168 (36%), Positives = 94/168 (55%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ G FG V+ VK+ + +ALKV+S ++ + V E + H F++
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH-PFLIRL 112
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
W ++ +Y++ EY+PGGEL + G + AEI AI++LH+ ++YRD
Sbjct: 113 FWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRD 172
Query: 841 LKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
LKPENILLD + HI+L DFG +K + RT TLCGT Y+ +I+S
Sbjct: 173 LKPENILLDRDGHIKLTDFGFAK--KLVDRTWTLCGTPEYLAPEVIQS 218
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 122 bits (294), Expect = 3e-27
Identities = 62/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V + + YA+K+L K ++ ++ V E ++
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ GK E + AEI+I + FLH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 122 bits (294), Expect = 3e-27
Identities = 60/183 (32%), Positives = 101/183 (55%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P + F+ T+ G+FG V V+ YA+K+L+K K+V V + E
Sbjct: 43 PAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEK 102
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
+I A F+V ++ +Y+V EY+PGGE+ +++ G+ E + A++
Sbjct: 103 RILQAIDF-PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVV 161
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNL 975
+A+ +LH+ +I+RDLKPEN+L+D + ++Q+ DFG +K + RT TLCGT Y+ +
Sbjct: 162 LAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAK--RVKGRTWTLCGTPEYLAPEI 219
Query: 976 IRS 984
I S
Sbjct: 220 ILS 222
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 122 bits (294), Expect = 3e-27
Identities = 66/202 (32%), Positives = 106/202 (52%), Gaps = 1/202 (0%)
Frame = +1
Query: 376 EASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVK-KVSENKEYAL 552
+ S A+ A ++ + E +L DF I T+ G FG V V+ K E+K +A+
Sbjct: 345 DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAM 404
Query: 553 KVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLG 732
K+L K IV+ ++ E +I H FIV ++ K +Y++ E GGEL
Sbjct: 405 KILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 463
Query: 733 LIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKW 912
++ G + + + A + A +LH+ G+IYRDLKPEN++LD + +L+DFG +K
Sbjct: 464 ILRDRGSFEDSTTRFYTACVVEAFAYLHSNGIIYRDLKPENLILDHRGYAKLVDFGFAKK 523
Query: 913 LSIGSRTTTLCGTLNYMVWNLI 978
+ G +T T CGT Y+ +I
Sbjct: 524 IGFGKKTWTFCGTPEYVAPEII 545
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 122 bits (294), Expect = 3e-27
Identities = 60/183 (32%), Positives = 101/183 (55%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P + F+ T+ G+FG V V+ YA+K+L+K K+V V + E
Sbjct: 34 PAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEK 93
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
+I A F+V ++ +Y+V EY+PGGE+ +++ G+ E + A++
Sbjct: 94 RILQAIDF-PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVV 152
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNL 975
+A+ +LH+ +I+RDLKPEN+L+D + ++Q+ DFG +K + RT TLCGT Y+ +
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAK--RVKGRTWTLCGTPEYLAPEI 210
Query: 976 IRS 984
I S
Sbjct: 211 ILS 213
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 122 bits (294), Expect = 3e-27
Identities = 62/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V + + YA+K+L K ++ ++ V E ++
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ GK E + AEI+I + FLH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 122 bits (294), Expect = 3e-27
Identities = 62/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V + + YA+K+L K ++ ++ V E ++
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ GK E + AEI+I + FLH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
>BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 122 bits (294), Expect = 3e-27
Identities = 62/168 (36%), Positives = 94/168 (55%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ G FG V+ VK+ + +ALKV+S ++ + V E + H F++
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH-PFLIRL 112
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
W ++ +Y++ EY+PGGEL + G + AEI AI++LH+ ++YRD
Sbjct: 113 FWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRD 172
Query: 841 LKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
LKPENILLD + HI+L DFG +K + RT TLCGT Y+ +I+S
Sbjct: 173 LKPENILLDRDGHIKLTDFGFAK--KLVDRTWTLCGTPEYLAPEVIQS 218
>BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 122 bits (294), Expect = 3e-27
Identities = 62/168 (36%), Positives = 94/168 (55%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ G FG V+ VK+ + +ALKV+S ++ + V E + H F++
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH-PFLIRL 112
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
W ++ +Y++ EY+PGGEL + G + AEI AI++LH+ ++YRD
Sbjct: 113 FWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRD 172
Query: 841 LKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLIRS 984
LKPENILLD + HI+L DFG +K + RT TLCGT Y+ +I+S
Sbjct: 173 LKPENILLDRDGHIKLTDFGFAK--KLVDRTWTLCGTPEYLAPEVIQS 218
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 122 bits (294), Expect = 3e-27
Identities = 60/183 (32%), Positives = 101/183 (55%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P + F+ T+ G+FG V V+ YA+K+L+K K+V V + E
Sbjct: 34 PAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEK 93
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
+I A F+V ++ +Y+V EY+PGGE+ +++ G+ E + A++
Sbjct: 94 RILQAIDF-PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVV 152
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNL 975
+A+ +LH+ +I+RDLKPEN+L+D + ++Q+ DFG +K + RT TLCGT Y+ +
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAK--RVKGRTWTLCGTPEYLAPEI 210
Query: 976 IRS 984
I S
Sbjct: 211 ILS 213
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 122 bits (294), Expect = 3e-27
Identities = 62/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V + + YA+K+L K ++ ++ V E ++
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ GK E + AEI+I + FLH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 122 bits (294), Expect = 3e-27
Identities = 60/183 (32%), Positives = 101/183 (55%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P + F+ T+ G+FG V V+ YA+K+L+K K+V V + E
Sbjct: 34 PAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEK 93
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
+I A F+V ++ +Y+V EY+PGGE+ +++ G+ E + A++
Sbjct: 94 RILQAIDF-PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVV 152
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNL 975
+A+ +LH+ +I+RDLKPEN+L+D + ++Q+ DFG +K + RT TLCGT Y+ +
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAK--RVKGRTWTLCGTPEYLAPEI 210
Query: 976 IRS 984
I S
Sbjct: 211 ILS 213
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 122 bits (294), Expect = 3e-27
Identities = 60/183 (32%), Positives = 101/183 (55%)
Frame = +1
Query: 436 PIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEA 615
P + F+ T+ G+FG V V+ YA+K+L+K K+V V + E
Sbjct: 34 PAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEK 93
Query: 616 KIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIA 795
+I A F+V ++ +Y+V EY+PGGE+ +++ G+ E + A++
Sbjct: 94 RILQAIDF-PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVV 152
Query: 796 IAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNL 975
+A+ +LH+ +I+RDLKPEN+L+D + ++Q+ DFG +K + RT TLCGT Y+ +
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAK--RVKGRTWTLCGTPEYLAPEI 210
Query: 976 IRS 984
I S
Sbjct: 211 ILS 213
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide dependent
protein kinase-1 variant protein.
Length = 556
Score = 121 bits (292), Expect = 5e-27
Identities = 65/187 (34%), Positives = 101/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A ++LH
Sbjct: 140 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLHG 198
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + HIQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 259 ACKSSDL 265
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 121 bits (291), Expect = 6e-27
Identities = 66/174 (37%), Positives = 98/174 (56%), Gaps = 1/174 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI-QTACG 636
++ +I T+A G FG V VK +EN +A+K + K IV+ V E +I + C
Sbjct: 451 QNLEIIATLAVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS 510
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
FIV ++ K +Y++ E GGEL ++ G E K VA + A D+LH
Sbjct: 511 --PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLH 568
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLKPEN++LDAE +++L+DFG +K + G +T T CGT Y+ +I
Sbjct: 569 RLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVI 622
>X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta II. ).
Length = 673
Score = 120 bits (290), Expect = 8e-27
Identities = 62/173 (35%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V ++ ++ YA+K+L K ++ ++ V E ++ G
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ G+ E + AEIAI + FL +
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 513
>X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta I. ).
Length = 671
Score = 120 bits (290), Expect = 8e-27
Identities = 62/173 (35%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V ++ ++ YA+K+L K ++ ++ V E ++ G
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ G+ E + AEIAI + FL +
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 513
>M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II
type protein.
Length = 673
Score = 120 bits (290), Expect = 8e-27
Identities = 62/173 (35%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V ++ ++ YA+K+L K ++ ++ V E ++ G
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ G+ E + AEIAI + FL +
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 513
>BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta 1
protein.
Length = 673
Score = 120 bits (290), Expect = 8e-27
Identities = 62/173 (35%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V ++ ++ YA+K+L K ++ ++ V E ++ G
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ G+ E + AEIAI + FL +
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 513
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 120 bits (290), Expect = 8e-27
Identities = 64/187 (34%), Positives = 102/187 (54%), Gaps = 3/187 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+DF+ + +G+F V ++++ ++EYA+K+L K I+ EN V V E + + H
Sbjct: 53 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 112
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
F V +Q +++Y Y GELL I K G E + + AEI A+++LH
Sbjct: 113 -PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 171
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS---RTTTLCGTLNYMVWNLIRSNY 990
G+I+RDLKPENILL+ + +IQ+ DFG +K LS S R + GT Y+ L+
Sbjct: 172 KGIIHRDLKPENILLNEDMYIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 231
Query: 991 KWQSASV 1011
+S+ +
Sbjct: 232 ACKSSDL 238
>AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (5'
partial) splice form_ protein.
Length = 496
Score = 120 bits (290), Expect = 8e-27
Identities = 62/173 (35%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V ++ ++ YA+K+L K ++ ++ V E ++ G
Sbjct: 164 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 223
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ G+ E + AEIAI + FL +
Sbjct: 224 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 283
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 284 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 336
>AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (5'
partial) splice form_1 protein.
Length = 494
Score = 120 bits (290), Expect = 8e-27
Identities = 62/173 (35%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG+FG V ++ ++ YA+K+L K ++ ++ V E ++ G
Sbjct: 164 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 223
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ S +QT R+Y V EY+ GG+L+ I++ G+ E + AEIAI + FL +
Sbjct: 224 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 283
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKW-LSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLK +N++LD+E HI++ DFG+ K + G T T CGT +Y+ +I
Sbjct: 284 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 336
>L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 369 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 426
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 486
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 487 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
>L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 369 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 426
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 486
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 487 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
>BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 369 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 426
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 486
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 487 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
>BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 369 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 426
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 486
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 487 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
>AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta
protein.
Length = 643
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 369 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 426
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 486
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 487 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
>AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 369 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 426
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 486
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 487 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
>AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 141 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 198
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 199 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 258
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 259 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 318
>AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 369 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 426
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 486
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 487 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
>AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 120 bits (289), Expect = 1e-26
Identities = 60/180 (33%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P IK + +DF + + KG+FG V+ + N+ +A+K L K ++ ++ V
Sbjct: 141 PSLQIKLKI--EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTM 198
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E ++ + H F+ +QTK+ ++ V EY+ GG+L+ I+ K + A
Sbjct: 199 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAA 258
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIG-SRTTTLCGTLNYM 963
EI + + FLH+ G++YRDLK +NILLD + HI++ DFG+ K +G ++T T CGT +Y+
Sbjct: 259 EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 318
>AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-
593] protein.
Length = 593
Score = 120 bits (289), Expect = 1e-26
Identities = 56/162 (34%), Positives = 101/162 (62%)
Frame = +1
Query: 457 QKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
+ DF+ I+ GA+G VY V+ + +A+K ++K ++ N ++QV E I T
Sbjct: 363 ESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFA- 421
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+ F+V ++T++ + +V EY+ GG+ L++ G LP ++ +++ AE +A+++LH
Sbjct: 422 ENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLH 481
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
N G+++RDLKP+N+L+ + HI+L DFGLSK + + S T L
Sbjct: 482 NYGIVHRDLKPDNLLITSLGHIKLTDFGLSK-IGLMSMATNL 522
>AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein.
Length = 1308
Score = 120 bits (289), Expect = 1e-26
Identities = 56/162 (34%), Positives = 101/162 (62%)
Frame = +1
Query: 457 QKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
+ DF+ I+ GA+G VY V+ + +A+K ++K ++ N ++QV E I T
Sbjct: 363 ESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFA- 421
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+ F+V ++T++ + +V EY+ GG+ L++ G LP ++ +++ AE +A+++LH
Sbjct: 422 ENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLH 481
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
N G+++RDLKP+N+L+ + HI+L DFGLSK + + S T L
Sbjct: 482 NYGIVHRDLKPDNLLITSLGHIKLTDFGLSK-IGLMSMATNL 522
>Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 198
Score = 120 bits (288), Expect = 1e-26
Identities = 63/164 (38%), Positives = 92/164 (56%), Gaps = 1/164 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF I KG +G V K+ S+ YA+KVL K I+ + + E + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKE-SHIMAERSVLLKNVRH 92
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+VG +QT +++Y V +Y+ GGEL +++ + E + + AE+A AI +LH+
Sbjct: 93 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 152
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGT 951
+IYRDLKPENILLD + H+ L DFGL K + T+T CGT
Sbjct: 153 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGT 196
>AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protein
kinase protein.
Length = 2434
Score = 120 bits (288), Expect = 1e-26
Identities = 56/162 (34%), Positives = 101/162 (62%)
Frame = +1
Query: 457 QKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
+ DF+ I+ GA+G VY V+ + +A+K ++K ++ N ++Q E I T
Sbjct: 378 ESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFA- 436
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+ F+V ++T++ + +V EY+ GG+ L++ G LP ++ +++ AE +A+++LH
Sbjct: 437 ENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLH 496
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
N G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 497 NYGIVHRDLKPDNLLVTSMGHIKLTDFGLSK-VGLMSMTTNL 537
>AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein.
Length = 2137
Score = 120 bits (288), Expect = 1e-26
Identities = 56/162 (34%), Positives = 101/162 (62%)
Frame = +1
Query: 457 QKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACG 636
+ DF+ I+ GA+G VY V+ + +A+K ++K ++ N ++Q E I T
Sbjct: 81 ESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFA- 139
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
+ F+V ++T++ + +V EY+ GG+ L++ G LP ++ +++ AE +A+++LH
Sbjct: 140 ENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLH 199
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTL 942
N G+++RDLKP+N+L+ + HI+L DFGLSK + + S TT L
Sbjct: 200 NYGIVHRDLKPDNLLVTSMGHIKLTDFGLSK-VGLMSMTTNL 240
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 119 bits (287), Expect = 2e-26
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI-QTACG 636
++ +I T+ G FG V VK +EN +A+K + K IV+ V E +I + C
Sbjct: 451 QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS 510
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
FIV ++ K +Y++ E GGEL ++ G E K VA + A D+LH
Sbjct: 511 --PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLH 568
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLKPEN++LDAE +++L+DFG +K + G +T T CGT Y+ +I
Sbjct: 569 RLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVI 622
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 119 bits (287), Expect = 2e-26
Identities = 65/174 (37%), Positives = 97/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI-QTACG 636
++ +I T+ G FG V VK +EN +A+K + K IV+ V E +I + C
Sbjct: 451 QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS 510
Query: 637 HHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH 816
FIV ++ K +Y++ E GGEL ++ G E K VA + A D+LH
Sbjct: 511 --PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLH 568
Query: 817 NAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMVWNLI 978
G+IYRDLKPEN++LDAE +++L+DFG +K + G +T T CGT Y+ +I
Sbjct: 569 RLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVI 622
>BC028603-1|AAH28603.1| 464|Homo sapiens serine/threonine kinase 38
like protein.
Length = 464
Score = 119 bits (287), Expect = 2e-26
Identities = 63/177 (35%), Positives = 104/177 (58%)
Frame = +1
Query: 403 AHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVN 582
A KE+ FL +T L DF+ I +GAFG+V V+K YA+K+L K+ ++
Sbjct: 71 ARKETEFLRLK--RTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLE 128
Query: 583 ENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPE 762
+ V ++ E I +++V +Q K+ +Y++ E++PGG+++ L+ K L E
Sbjct: 129 KEQVAHIRAERDILVEADG-AWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTE 187
Query: 763 EIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRT 933
E + +++E +AID +H G I+RD+KP+N+LLDA+ H++L DFGL L RT
Sbjct: 188 EETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRT 244
>AB023182-1|BAA76809.2| 489|Homo sapiens KIAA0965 protein protein.
Length = 489
Score = 119 bits (287), Expect = 2e-26
Identities = 63/177 (35%), Positives = 104/177 (58%)
Frame = +1
Query: 403 AHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVN 582
A KE+ FL +T L DF+ I +GAFG+V V+K YA+K+L K+ ++
Sbjct: 96 ARKETEFLRLK--RTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLE 153
Query: 583 ENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPE 762
+ V ++ E I +++V +Q K+ +Y++ E++PGG+++ L+ K L E
Sbjct: 154 KEQVAHIRAERDILVEADG-AWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTE 212
Query: 763 EIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRT 933
E + +++E +AID +H G I+RD+KP+N+LLDA+ H++L DFGL L RT
Sbjct: 213 EETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRT 269
>Z85986-3|CAB39180.1| 465|Homo sapiens serine/threonine kinase 38
protein.
Length = 465
Score = 119 bits (286), Expect = 2e-26
Identities = 64/177 (36%), Positives = 103/177 (58%)
Frame = +1
Query: 403 AHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVN 582
A KE+ FL +T L +DF+ I +GAFG+V V+K YA+K+L KA ++
Sbjct: 70 ARKETEFLRLK--RTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLE 127
Query: 583 ENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPE 762
+ V ++ E I ++V +Q K +Y++ E++PGG+++ L+ K L E
Sbjct: 128 KEQVGHIRAERDILVEADS-LWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTE 186
Query: 763 EIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRT 933
E + ++AE +AID +H G I+RD+KP+N+LLD++ H++L DFGL L RT
Sbjct: 187 EETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRT 243
>Z35102-1|CAA84485.1| 465|Homo sapiens Ndr protein kinase protein.
Length = 465
Score = 119 bits (286), Expect = 2e-26
Identities = 64/177 (36%), Positives = 103/177 (58%)
Frame = +1
Query: 403 AHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVN 582
A KE+ FL +T L +DF+ I +GAFG+V V+K YA+K+L KA ++
Sbjct: 70 ARKETEFLRLK--RTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLE 127
Query: 583 ENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPE 762
+ V ++ E I ++V +Q K +Y++ E++PGG+++ L+ K L E
Sbjct: 128 KEQVGHIRAERDILVEADS-LWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTE 186
Query: 763 EIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRT 933
E + ++AE +AID +H G I+RD+KP+N+LLD++ H++L DFGL L RT
Sbjct: 187 EETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRT 243
>BC095413-1|AAH95413.1| 465|Homo sapiens serine/threonine kinase 38
protein.
Length = 465
Score = 119 bits (286), Expect = 2e-26
Identities = 64/177 (36%), Positives = 103/177 (58%)
Frame = +1
Query: 403 AHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVN 582
A KE+ FL +T L +DF+ I +GAFG+V V+K YA+K+L KA ++
Sbjct: 70 ARKETEFLRLK--RTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLE 127
Query: 583 ENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPE 762
+ V ++ E I ++V +Q K +Y++ E++PGG+++ L+ K L E
Sbjct: 128 KEQVGHIRAERDILVEADS-LWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTE 186
Query: 763 EIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRT 933
E + ++AE +AID +H G I+RD+KP+N+LLD++ H++L DFGL L RT
Sbjct: 187 EETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRT 243
>BC012085-1|AAH12085.1| 465|Homo sapiens serine/threonine kinase 38
protein.
Length = 465
Score = 119 bits (286), Expect = 2e-26
Identities = 64/177 (36%), Positives = 103/177 (58%)
Frame = +1
Query: 403 AHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVN 582
A KE+ FL +T L +DF+ I +GAFG+V V+K YA+K+L KA ++
Sbjct: 70 ARKETEFLRLK--RTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLE 127
Query: 583 ENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPE 762
+ V ++ E I ++V +Q K +Y++ E++PGG+++ L+ K L E
Sbjct: 128 KEQVGHIRAERDILVEADS-LWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTE 186
Query: 763 EIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRT 933
E + ++AE +AID +H G I+RD+KP+N+LLD++ H++L DFGL L RT
Sbjct: 187 EETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRT 243
>AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase
protein.
Length = 486
Score = 118 bits (285), Expect = 3e-26
Identities = 63/186 (33%), Positives = 104/186 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P F K D+ FQI I KG+FG V V+K K YA+K ++K + + + VR V
Sbjct: 80 PVFDDKEDVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVF 139
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E +I H F+V +Q ++ +++V + + GG+L +++ + E+ V++++
Sbjct: 140 RELEILQEI-EHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYIC 198
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMV 966
E+A+A+D+L +I+RD+KP+NILLD H L DF ++ + G R T L GT YM
Sbjct: 199 EMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMA 258
Query: 967 WNLIRS 984
+ S
Sbjct: 259 PEIFHS 264
>AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE)
protein.
Length = 486
Score = 118 bits (285), Expect = 3e-26
Identities = 63/186 (33%), Positives = 104/186 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P F K D+ FQI I KG+FG V V+K K YA+K ++K + + + VR V
Sbjct: 80 PVFDDKEDVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVF 139
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E +I H F+V +Q ++ +++V + + GG+L +++ + E+ V++++
Sbjct: 140 RELEILQEI-EHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYIC 198
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMV 966
E+A+A+D+L +I+RD+KP+NILLD H L DF ++ + G R T L GT YM
Sbjct: 199 EMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMA 258
Query: 967 WNLIRS 984
+ S
Sbjct: 259 PEIFHS 264
>AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE)
protein.
Length = 486
Score = 118 bits (285), Expect = 3e-26
Identities = 63/186 (33%), Positives = 104/186 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P F K D+ FQI I KG+FG V V+K K YA+K ++K + + + VR V
Sbjct: 80 PVFDDKEDVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVF 139
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E +I H F+V +Q ++ +++V + + GG+L +++ + E+ V++++
Sbjct: 140 RELEILQEI-EHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYIC 198
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYMV 966
E+A+A+D+L +I+RD+KP+NILLD H L DF ++ + G R T L GT YM
Sbjct: 199 EMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMA 258
Query: 967 WNLIRS 984
+ S
Sbjct: 259 PEIFHS 264
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 117 bits (282), Expect = 7e-26
Identities = 61/174 (35%), Positives = 98/174 (56%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
+F+ + KG+FG V + YA+KVL K I+ ++ V E +I + +H
Sbjct: 354 NFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNH 413
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QT R++ V E++ GG+L+ I+K + E + + AEI A+ FLH+
Sbjct: 414 PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDK 473
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLD E H +L DFG+ K + G T T CGT +Y+ +++
Sbjct: 474 GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQ 527
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 117 bits (282), Expect = 7e-26
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++LD + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>AL356285-1|CAI15861.1| 1088|Homo sapiens LATS, large tumor
suppressor, homolog 2 (Drosophila) protein.
Length = 1088
Score = 117 bits (281), Expect = 1e-25
Identities = 56/141 (39%), Positives = 87/141 (61%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V KV + YA+K L K ++N N V VK E I A + ++V
Sbjct: 673 TLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDI-LAEADNEWVVKL 731
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + PE + + ++AE+ +AI+ +H G I+RD
Sbjct: 732 YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRD 791
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 792 IKPDNILIDLDGHIKLTDFGL 812
>AL161613-1|CAH71526.1| 1088|Homo sapiens LATS, large tumor
suppressor, homolog 2 (Drosophila) protein.
Length = 1088
Score = 117 bits (281), Expect = 1e-25
Identities = 56/141 (39%), Positives = 87/141 (61%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V KV + YA+K L K ++N N V VK E I A + ++V
Sbjct: 673 TLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDI-LAEADNEWVVKL 731
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + PE + + ++AE+ +AI+ +H G I+RD
Sbjct: 732 YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRD 791
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 792 IKPDNILIDLDGHIKLTDFGL 812
>AB209897-1|BAD93134.1| 924|Homo sapiens LATS, large tumor
suppressor, homolog 2 variant protein.
Length = 924
Score = 117 bits (281), Expect = 1e-25
Identities = 56/141 (39%), Positives = 87/141 (61%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V KV + YA+K L K ++N N V VK E I A + ++V
Sbjct: 679 TLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDI-LAEADNEWVVKL 737
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + PE + + ++AE+ +AI+ +H G I+RD
Sbjct: 738 YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRD 797
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 798 IKPDNILIDLDGHIKLTDFGL 818
>AB028019-1|BAA92381.1| 1046|Homo sapiens large tumor suppressor 2
protein.
Length = 1046
Score = 117 bits (281), Expect = 1e-25
Identities = 56/141 (39%), Positives = 87/141 (61%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V KV + YA+K L K ++N N V VK E I A + ++V
Sbjct: 631 TLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDI-LAEADNEWVVKL 689
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + PE + + ++AE+ +AI+ +H G I+RD
Sbjct: 690 YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRD 749
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 750 IKPDNILIDLDGHIKLTDFGL 770
>BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein.
Length = 524
Score = 116 bits (280), Expect = 1e-25
Identities = 64/181 (35%), Positives = 103/181 (56%), Gaps = 6/181 (3%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNENAVRQ-VKEEAKIQT 627
++F++ + GA+G V+ V+K + K YA+KVL KA +V ++ + E +
Sbjct: 31 ENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLE 90
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT +++++ +Y+ GGE+ + + E V+++ EI +A++
Sbjct: 91 LVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALE 150
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK--WLSIGSRTTTLCGTLNYMVWNLIR 981
LH G+IYRDLK EN+LLD+E HI L DFGLSK RT + CGT+ YM +IR
Sbjct: 151 HLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIR 210
Query: 982 S 984
S
Sbjct: 211 S 211
>BC028079-1|AAH28079.1| 556|Homo sapiens RPS6KA4 protein protein.
Length = 556
Score = 116 bits (280), Expect = 1e-25
Identities = 64/181 (35%), Positives = 103/181 (56%), Gaps = 6/181 (3%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNENAVRQ-VKEEAKIQT 627
++F++ + GA+G V+ V+K + K YA+KVL KA +V ++ + E +
Sbjct: 31 ENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLE 90
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT +++++ +Y+ GGE+ + + E V+++ EI +A++
Sbjct: 91 LVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALE 150
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK--WLSIGSRTTTLCGTLNYMVWNLIR 981
LH G+IYRDLK EN+LLD+E HI L DFGLSK RT + CGT+ YM +IR
Sbjct: 151 HLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIR 210
Query: 982 S 984
S
Sbjct: 211 S 211
Score = 65.7 bits (153), Expect = 3e-10
Identities = 44/146 (30%), Positives = 75/146 (51%), Gaps = 4/146 (2%)
Frame = +1
Query: 484 IAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAV 663
+ +G+F + ++ +E+A+K+LS+ + N R+V A ++ C H +V
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRR--LEANTQREV---AALRL-CQSHPNVVNLH 470
Query: 664 SRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH-NAGVIYRD 840
+ Y+V E + GGELL I K E + + A+ F+H AGV++RD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 841 LKPENILLDAE---CHIQLIDFGLSK 909
LKPENIL + +++IDFG ++
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFAR 556
>AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 4 isoform b variant protein.
Length = 765
Score = 116 bits (280), Expect = 1e-25
Identities = 64/181 (35%), Positives = 103/181 (56%), Gaps = 6/181 (3%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNENAVRQ-VKEEAKIQT 627
++F++ + GA+G V+ V+K + K YA+KVL KA +V ++ + E +
Sbjct: 31 ENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLE 90
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT +++++ +Y+ GGE+ + + E V+++ EI +A++
Sbjct: 91 LVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALE 150
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK--WLSIGSRTTTLCGTLNYMVWNLIR 981
LH G+IYRDLK EN+LLD+E HI L DFGLSK RT + CGT+ YM +IR
Sbjct: 151 HLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIR 210
Query: 982 S 984
S
Sbjct: 211 S 211
Score = 70.5 bits (165), Expect = 1e-11
Identities = 53/186 (28%), Positives = 92/186 (49%), Gaps = 7/186 (3%)
Frame = +1
Query: 442 KTDLLQKDFQIQH-TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAK 618
++ ++Q + ++ + +G+F + ++ +E+A+K+LS+ + N R+V A
Sbjct: 395 RSAMMQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRR--LEANTQREV---AA 449
Query: 619 IQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAI 798
++ C H +V + Y+V E + GGELL I K E + +
Sbjct: 450 LRL-CQSHPNVVNLHEVHHDQPHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVS 508
Query: 799 AIDFLH-NAGVIYRDLKPENILLDAE---CHIQLIDFGLSKW--LSIGSRTTTLCGTLNY 960
A+ F+H AGV++RDLKPENIL + +++IDFG ++ S G T C TL Y
Sbjct: 509 AVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQY 568
Query: 961 MVWNLI 978
L+
Sbjct: 569 AAPELL 574
>AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinase B
(RSK-B) protein.
Length = 772
Score = 116 bits (280), Expect = 1e-25
Identities = 64/181 (35%), Positives = 103/181 (56%), Gaps = 6/181 (3%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNENAVRQ-VKEEAKIQT 627
++F++ + GA+G V+ V+K + K YA+KVL KA +V ++ + E +
Sbjct: 31 ENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLE 90
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT +++++ +Y+ GGE+ + + E V+++ EI +A++
Sbjct: 91 LVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALE 150
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK--WLSIGSRTTTLCGTLNYMVWNLIR 981
LH G+IYRDLK EN+LLD+E HI L DFGLSK RT + CGT+ YM +IR
Sbjct: 151 HLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIR 210
Query: 982 S 984
S
Sbjct: 211 S 211
Score = 69.3 bits (162), Expect = 3e-11
Identities = 52/171 (30%), Positives = 84/171 (49%), Gaps = 6/171 (3%)
Frame = +1
Query: 484 IAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAV 663
+ +G+F + ++ +E+A+K+LS+ + N R+V A ++ C H +V
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRR--LEANTQREV---AALRL-CQSHPNVVNLH 470
Query: 664 SRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH-NAGVIYRD 840
+ Y+V E + GGELL I K E + + A+ F+H AGV++RD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 841 LKPENILLDAE---CHIQLIDFGLSKW--LSIGSRTTTLCGTLNYMVWNLI 978
LKPENIL + +++IDFG ++ S G T C TL Y L+
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELL 581
>AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and
stress-activated protein kinase-2 protein.
Length = 705
Score = 116 bits (280), Expect = 1e-25
Identities = 64/181 (35%), Positives = 103/181 (56%), Gaps = 6/181 (3%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSEN---KEYALKVLSKAKIVNENAVRQ-VKEEAKIQT 627
++F++ + GA+G V+ V+K + K YA+KVL KA +V ++ + E +
Sbjct: 15 ENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLE 74
Query: 628 ACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAID 807
F+V +QT +++++ +Y+ GGE+ + + E V+++ EI +A++
Sbjct: 75 LVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALE 134
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK--WLSIGSRTTTLCGTLNYMVWNLIR 981
LH G+IYRDLK EN+LLD+E HI L DFGLSK RT + CGT+ YM +IR
Sbjct: 135 HLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIR 194
Query: 982 S 984
S
Sbjct: 195 S 195
Score = 69.3 bits (162), Expect = 3e-11
Identities = 52/171 (30%), Positives = 84/171 (49%), Gaps = 6/171 (3%)
Frame = +1
Query: 484 IAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAV 663
+ +G+F + ++ +E+A+K+LS+ + N R+V A ++ C H +V
Sbjct: 395 LGQGSFSVCRRCRQRQSGQEFAVKILSRR--LEANTQREV---AALRL-CQSHPNVVNLH 448
Query: 664 SRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLH-NAGVIYRD 840
+ Y+V E + GGELL I K E + + A+ F+H AGV++RD
Sbjct: 449 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 508
Query: 841 LKPENILLDAE---CHIQLIDFGLSKW--LSIGSRTTTLCGTLNYMVWNLI 978
LKPENIL + +++IDFG ++ S G T C TL Y L+
Sbjct: 509 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELL 559
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 116 bits (279), Expect = 2e-25
Identities = 61/174 (35%), Positives = 98/174 (56%), Gaps = 1/174 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
+F+ + KG+FG V + YA+KVL K I+ ++ V E +I + +H
Sbjct: 353 NFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLARNH 412
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QT R++ V E++ GG+L+ I+K + E + + AEI A+ FLH+
Sbjct: 413 PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDK 472
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIR 981
G+IYRDLK +N+LLD E H +L DFG+ K + G T T CGT +Y+ +++
Sbjct: 473 GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQ 526
>AF207547-1|AAF80561.1| 1088|Homo sapiens serine/threonine kinase KPM
protein.
Length = 1088
Score = 116 bits (279), Expect = 2e-25
Identities = 56/141 (39%), Positives = 87/141 (61%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V KV + YA+K L K ++N N V VK E I A + ++V
Sbjct: 673 TLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERDI-LAEADNEWVVKL 731
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + PE + + ++AE+ +AI+ +H G I+RD
Sbjct: 732 YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRD 791
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 792 IKPDNILIDLDGHIKLTDFGL 812
>BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 115 bits (277), Expect = 3e-25
Identities = 60/182 (32%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P P + +DF+ + +G FG V V+ K YA+K L K ++++ + + +
Sbjct: 546 PASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLY 605
Query: 607 EEAKIQTA--CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIF 780
E +I A C H F++ ++ +QT V+E++PGG+L+ I + PE + +
Sbjct: 606 CEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFY 664
Query: 781 VAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLN 957
VA + + + FLH +IYRDLK +N+LLDA+ +++ DFGL K + G RT+T CGT
Sbjct: 665 VACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPE 724
Query: 958 YM 963
++
Sbjct: 725 FL 726
>AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 115 bits (277), Expect = 3e-25
Identities = 60/182 (32%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P P + +DF+ + +G FG V V+ K YA+K L K ++++ + + +
Sbjct: 546 PASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLY 605
Query: 607 EEAKIQTA--CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIF 780
E +I A C H F++ ++ +QT V+E++PGG+L+ I + PE + +
Sbjct: 606 CEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFY 664
Query: 781 VAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLN 957
VA + + + FLH +IYRDLK +N+LLDA+ +++ DFGL K + G RT+T CGT
Sbjct: 665 VACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPE 724
Query: 958 YM 963
++
Sbjct: 725 FL 726
>AF164041-1|AAD50272.1| 1130|Homo sapiens WARTS protein kinase
protein.
Length = 1130
Score = 115 bits (277), Expect = 3e-25
Identities = 55/141 (39%), Positives = 85/141 (60%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V +KV YA K L K ++ N V VK E I A + ++V
Sbjct: 710 TLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDI-LAEADNEWVVRL 768
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + G PE + + ++AE+ A++ +H G I+RD
Sbjct: 769 YYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRD 828
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 829 IKPDNILIDRDGHIKLTDFGL 849
>AF104413-1|AAD16882.1| 1130|Homo sapiens large tumor suppressor 1
protein.
Length = 1130
Score = 115 bits (277), Expect = 3e-25
Identities = 55/141 (39%), Positives = 85/141 (60%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V +KV YA K L K ++ N V VK E I A + ++V
Sbjct: 710 TLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDI-LAEADNEWVVRL 768
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + G PE + + ++AE+ A++ +H G I+RD
Sbjct: 769 YYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRD 828
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 829 IKPDNILIDRDGHIKLTDFGL 849
>AB209426-1|BAD92663.1| 830|Homo sapiens LATS homolog 1 variant
protein.
Length = 830
Score = 115 bits (277), Expect = 3e-25
Identities = 55/141 (39%), Positives = 85/141 (60%)
Frame = +1
Query: 481 TIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGA 660
T+ GAFG+V +KV YA K L K ++ N V VK E I A + ++V
Sbjct: 562 TLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDI-LAEADNEWVVRL 620
Query: 661 VSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRD 840
+Q K +Y V +YIPGG+++ L+ + G PE + + ++AE+ A++ +H G I+RD
Sbjct: 621 YYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRD 680
Query: 841 LKPENILLDAECHIQLIDFGL 903
+KP+NIL+D + HI+L DFGL
Sbjct: 681 IKPDNILIDRDGHIKLTDFGL 701
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 115 bits (276), Expect = 4e-25
Identities = 60/177 (33%), Positives = 106/177 (59%), Gaps = 2/177 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+D+++ I +GAFG+V V+ S K YA+K+LSK +++ + EE I A +
Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIM-AFAN 132
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
++V +Q + +Y+V EY+PGG+L+ L+ Y +PE+ + + AE+ +A+D +H+
Sbjct: 133 SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDAIHS 191
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGS--RTTTLCGTLNYMVWNLIRS 984
G I+RD+KP+N+LLD H++L DFG ++ R T GT +Y+ +++S
Sbjct: 192 MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKS 248
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 115 bits (276), Expect = 4e-25
Identities = 59/176 (33%), Positives = 96/176 (54%), Gaps = 1/176 (0%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF + KG FG V V++ + K YA+K+L K I+ ++ V E+++ H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT-RH 205
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
F+ +QTK R+ V EY+ GGEL + + E+ + + AEI A+D+LH+
Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLIRSN 987
++YRDLK EN++ D + HI++ DFGL K ++ + T CGT Y+ ++ N
Sbjct: 266 KIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 114 bits (275), Expect = 5e-25
Identities = 60/183 (32%), Positives = 98/183 (53%), Gaps = 1/183 (0%)
Frame = +1
Query: 442 KTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI 621
+ + DF + KG FG V V++ + + YA+K+L K I+ ++ V E+++
Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203
Query: 622 QTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIA 801
H F+ +QT R+ V EY GGEL + + EE + + AEI A
Sbjct: 204 LQNT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSA 262
Query: 802 IDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
+++LH+ V+YRD+K EN++LD + HI++ DFGL K +S G+ T CGT Y+ ++
Sbjct: 263 LEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
Query: 979 RSN 987
N
Sbjct: 323 EDN 325
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 114 bits (275), Expect = 5e-25
Identities = 60/183 (32%), Positives = 98/183 (53%), Gaps = 1/183 (0%)
Frame = +1
Query: 442 KTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI 621
+ + DF + KG FG V V++ + + YA+K+L K I+ ++ V E+++
Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203
Query: 622 QTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIA 801
H F+ +QT R+ V EY GGEL + + EE + + AEI A
Sbjct: 204 LQNT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSA 262
Query: 802 IDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
+++LH+ V+YRD+K EN++LD + HI++ DFGL K +S G+ T CGT Y+ ++
Sbjct: 263 LEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
Query: 979 RSN 987
N
Sbjct: 323 EDN 325
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 114 bits (275), Expect = 5e-25
Identities = 60/183 (32%), Positives = 98/183 (53%), Gaps = 1/183 (0%)
Frame = +1
Query: 442 KTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI 621
+ + DF + KG FG V V++ + + YA+K+L K I+ ++ V E+++
Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203
Query: 622 QTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIA 801
H F+ +QT R+ V EY GGEL + + EE + + AEI A
Sbjct: 204 LQNT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSA 262
Query: 802 IDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
+++LH+ V+YRD+K EN++LD + HI++ DFGL K +S G+ T CGT Y+ ++
Sbjct: 263 LEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
Query: 979 RSN 987
N
Sbjct: 323 EDN 325
>BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein.
Length = 344
Score = 114 bits (275), Expect = 5e-25
Identities = 60/183 (32%), Positives = 98/183 (53%), Gaps = 1/183 (0%)
Frame = +1
Query: 442 KTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKI 621
+ + DF + KG FG V V++ + + YA+K+L K I+ ++ V E+++
Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203
Query: 622 QTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIA 801
H F+ +QT R+ V EY GGEL + + EE + + AEI A
Sbjct: 204 LQNT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSA 262
Query: 802 IDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLNYMVWNLI 978
+++LH+ V+YRD+K EN++LD + HI++ DFGL K +S G+ T CGT Y+ ++
Sbjct: 263 LEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
Query: 979 RSN 987
N
Sbjct: 323 EDN 325
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 114 bits (275), Expect = 5e-25
Identities = 63/179 (35%), Positives = 99/179 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P P L DF+I + KG FG+VY + + ALKVL K++I E Q++
Sbjct: 30 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR 89
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E +IQ H + I+ + + +R+Y++ EY P GEL ++K KL E+ +
Sbjct: 90 REIEIQAHLQHPN-ILRLYNHFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIE 148
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYM 963
E+A A+ + H+ VI+RD+KPEN+LL +++ DFG S + R T+CGTL+Y+
Sbjct: 149 ELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVH-TPSLRRKTMCGTLDYL 206
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 114 bits (274), Expect = 7e-25
Identities = 67/205 (32%), Positives = 107/205 (52%)
Frame = +1
Query: 349 NDSTLKNPLEASKTAWPVAHKESIFLPEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKV 528
N K PL ++ P S E K +DF+I + KG FG+VY ++
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 529 SENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEY 708
ALKVL KA++ Q++ E +IQ+ H + I+ + R+Y++ EY
Sbjct: 154 QSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEY 212
Query: 709 IPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQL 888
P G + ++K K E+ ++ E+A A+ + H+ VI+RD+KPEN+LL + +++
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 889 IDFGLSKWLSIGSRTTTLCGTLNYM 963
DFG S + SR TTLCGTL+Y+
Sbjct: 273 ADFGWSVH-APSSRRTTLCGTLDYL 296
>AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta
protein.
Length = 889
Score = 114 bits (274), Expect = 7e-25
Identities = 60/182 (32%), Positives = 101/182 (55%), Gaps = 3/182 (1%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P P + +DF+ + +G FG V V+ K YA+K L K ++++ + + +
Sbjct: 546 PASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLY 605
Query: 607 EEAKIQTA--CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIF 780
E +I A C H F++ + +QT V+E++PGG+L+ I + PE + +
Sbjct: 606 CEKRILEAVGCTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHE-DVFPEPQARFY 664
Query: 781 VAEIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSK-WLSIGSRTTTLCGTLN 957
VA + + + FLH +IYRDLK +N+LLDA+ +++ DFGL K + G RT+T CGT
Sbjct: 665 VACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPE 724
Query: 958 YM 963
++
Sbjct: 725 FL 726
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 113 bits (273), Expect = 9e-25
Identities = 61/177 (34%), Positives = 105/177 (59%), Gaps = 2/177 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+D+ + I +GAFG+V V+ + K YA+K+LSK +++ + EE I A +
Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIM-AFAN 148
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
++V +Q + +Y+V EY+PGG+L+ L+ Y +PE+ K + AE+ +A+D +H+
Sbjct: 149 SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWAKFYTAEVVLALDAIHS 207
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYMVWNLIRS 984
G+I+RD+KP+N+LLD H++L DFG K G T GT +Y+ +++S
Sbjct: 208 MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKS 264
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 113 bits (273), Expect = 9e-25
Identities = 63/179 (35%), Positives = 99/179 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P P L DF+I + KG FG+VY + + ALKVL K++I E Q++
Sbjct: 27 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR 86
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E +IQ H + I+ + + +R+Y++ EY P GEL ++K KL E+ +
Sbjct: 87 REIEIQAHLQHPN-ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIE 145
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYM 963
E+A A+ + H+ VI+RD+KPEN+LL +++ DFG S + R T+CGTL+Y+
Sbjct: 146 ELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVH-TPSLRRKTMCGTLDYL 203
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 113 bits (273), Expect = 9e-25
Identities = 63/179 (35%), Positives = 99/179 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P P L DF+I + KG FG+VY + + ALKVL K++I E Q++
Sbjct: 11 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR 70
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E +IQ H + I+ + + +R+Y++ EY P GEL ++K KL E+ +
Sbjct: 71 REIEIQAHLQHPN-ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIE 129
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYM 963
E+A A+ + H+ VI+RD+KPEN+LL +++ DFG S + R T+CGTL+Y+
Sbjct: 130 ELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVH-TPSLRRKTMCGTLDYL 187
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 113 bits (273), Expect = 9e-25
Identities = 61/177 (34%), Positives = 105/177 (59%), Gaps = 2/177 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+D+ + I +GAFG+V V+ + K YA+K+LSK +++ + EE I A +
Sbjct: 43 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIM-AFAN 101
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
++V +Q + +Y+V EY+PGG+L+ L+ Y +PE+ K + AE+ +A+D +H+
Sbjct: 102 SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWAKFYTAEVVLALDAIHS 160
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYMVWNLIRS 984
G+I+RD+KP+N+LLD H++L DFG K G T GT +Y+ +++S
Sbjct: 161 MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKS 217
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 113 bits (273), Expect = 9e-25
Identities = 63/179 (35%), Positives = 99/179 (55%)
Frame = +1
Query: 427 PEFPIKTDLLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVK 606
P P L DF+I + KG FG+VY + + ALKVL K++I E Q++
Sbjct: 30 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR 89
Query: 607 EEAKIQTACGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVA 786
E +IQ H + I+ + + +R+Y++ EY P GEL ++K KL E+ +
Sbjct: 90 REIEIQAHLQHPN-ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIE 148
Query: 787 EIAIAIDFLHNAGVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYM 963
E+A A+ + H+ VI+RD+KPEN+LL +++ DFG S + R T+CGTL+Y+
Sbjct: 149 ELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVH-TPSLRRKTMCGTLDYL 206
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 113 bits (273), Expect = 9e-25
Identities = 61/177 (34%), Positives = 105/177 (59%), Gaps = 2/177 (1%)
Frame = +1
Query: 460 KDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGH 639
+D+ + I +GAFG+V V+ + K YA+K+LSK +++ + EE I A +
Sbjct: 130 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIM-AFAN 188
Query: 640 HSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHN 819
++V +Q + +Y+V EY+PGG+L+ L+ Y +PE+ K + AE+ +A+D +H+
Sbjct: 189 SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWAKFYTAEVVLALDAIHS 247
Query: 820 AGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYMVWNLIRS 984
G+I+RD+KP+N+LLD H++L DFG K G T GT +Y+ +++S
Sbjct: 248 MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKS 304
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 112 bits (270), Expect = 2e-24
Identities = 60/167 (35%), Positives = 96/167 (57%)
Frame = +1
Query: 463 DFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTACGHH 642
DF+I + KG FG+VY + + ALKVL K++I E Q++ E +IQ H
Sbjct: 8 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 67
Query: 643 SFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYGKLPEEIVKIFVAEIAIAIDFLHNA 822
+ I+ + + +R+Y++ EY P GEL ++K KL E+ + E+A A+ + H+
Sbjct: 68 N-ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHDK 126
Query: 823 GVIYRDLKPENILLDAECHIQLIDFGLSKWLSIGSRTTTLCGTLNYM 963
VI+RD+KPEN+LL +++ DFG S + R T+CGTL+Y+
Sbjct: 127 KVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPER-KTMCGTLDYL 172
>S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase
protein.
Length = 625
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 66 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 125
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 126 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 184
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 185 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 238
>M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein.
Length = 582
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 25 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 84
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 85 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 143
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 144 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 197
>L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein.
Length = 624
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 66 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 125
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 126 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 184
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 185 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 238
>L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase
protein.
Length = 530
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 66 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 125
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 126 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 184
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 185 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 238
>L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase
protein.
Length = 535
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 66 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 125
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 126 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 184
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 185 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 238
>L08835-3|AAC14448.1| 624|Homo sapiens myotonic dystrophy kinase
protein.
Length = 624
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 66 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 125
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 126 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 184
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 185 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 238
>L08835-2|AAC14449.1| 629|Homo sapiens myotonic dystrophy kinase
protein.
Length = 629
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 66 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 125
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 126 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 184
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 185 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 238
>L00727-5|AAA75237.1| 545|Homo sapiens myotonin-protein kinase,
Form VIII protein.
Length = 545
Score = 112 bits (269), Expect = 3e-24
Identities = 63/174 (36%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Frame = +1
Query: 451 LLQKDFQIQHTIAKGAFGDVYKVKKVSENKEYALKVLSKAKIVNENAVRQVKEEAKIQTA 630
L + DF+I I +GAF +V VK + YA+K+++K ++ V +EE +
Sbjct: 76 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 135
Query: 631 CGHHSFIVGAVSRWQTKKRIYIVSEYIPGGELLGLIEKYG-KLPEEIVKIFVAEIAIAID 807
G +I +Q + +Y+V EY GG+LL L+ K+G ++P E+ + ++AEI +AID
Sbjct: 136 -GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 194
Query: 808 FLHNAGVIYRDLKPENILLDAECHIQLIDFG-LSKWLSIGS-RTTTLCGTLNYM 963
+H G ++RD+KP+NILLD HI+L DFG K + G+ R+ GT +Y+
Sbjct: 195 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYL 248
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 163,199,015
Number of Sequences: 237096
Number of extensions: 3358902
Number of successful extensions: 10029
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 8147
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8696
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17174423760
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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