Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_F17
(1234 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U36308-1|AAC02794.2| 263|Homo sapiens lens major intrinsic prot... 93 2e-18
BC117474-1|AAI17475.1| 263|Homo sapiens major intrinsic protein... 93 2e-18
BC074913-1|AAH74913.1| 263|Homo sapiens major intrinsic protein... 93 2e-18
AF000143-1|AAC03168.1| 263|Homo sapiens putative alternative le... 88 5e-17
Z29491-1|CAA82627.1| 271|Homo sapiens water channel aquaporin-2... 83 2e-15
D31846-1|BAA06632.1| 271|Homo sapiens human aquaporin-2 water c... 83 2e-15
BC042496-1|AAH42496.1| 271|Homo sapiens aquaporin 2 (collecting... 83 2e-15
AF147093-1|AAD38692.1| 271|Homo sapiens aquaporin 2 protein. 83 2e-15
CR542024-1|CAG46821.1| 271|Homo sapiens AQP2 protein. 81 8e-15
S73197-1|AAB31998.1| 271|Homo sapiens water-channel aquaporin 2... 80 1e-14
S73196-1|AAB31999.1| 271|Homo sapiens water-channel aquaporin 2... 80 1e-14
AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a v... 80 1e-14
U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein. 80 2e-14
U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein. 80 2e-14
U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive wat... 80 2e-14
U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive wat... 80 2e-14
D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein. 80 2e-14
BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein. 80 2e-14
BC022486-1|AAH22486.1| 269|Homo sapiens aquaporin 1 (Colton blo... 78 6e-14
U41517-1|AAC50648.1| 269|Homo sapiens channel-like integral mem... 78 8e-14
S73482-1|AAB31193.1| 269|Homo sapiens uterine water channel pro... 78 8e-14
M77829-1|AAA58425.1| 269|Homo sapiens channel-like integral mem... 78 8e-14
AY953319-1|AAX24129.1| 269|Homo sapiens aquaporin 1 (channel-fo... 78 8e-14
AF480415-1|AAL87136.1| 265|Homo sapiens aquaporin 1 protein. 78 8e-14
U46569-1|AAC50474.1| 265|Homo sapiens aquaporin-5 protein. 76 2e-13
CR542022-1|CAG46819.1| 265|Homo sapiens AQP5 protein. 76 2e-13
CR541989-1|CAG46786.1| 265|Homo sapiens AQP5 protein. 76 2e-13
BC032946-1|AAH32946.1| 265|Homo sapiens aquaporin 5 protein. 76 2e-13
U48408-1|AAB41566.1| 282|Homo sapiens water channel protein. 75 4e-13
U41518-1|AAC50649.1| 152|Homo sapiens channel-like integral mem... 58 5e-08
AC005155-1|AAC23788.1| 141|Homo sapiens aquaporin protein. 58 5e-08
AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcr... 58 5e-08
BC040630-1|AAH40630.1| 255|Homo sapiens AQP8 protein protein. 58 7e-08
AK222975-1|BAD96695.1| 261|Homo sapiens aquaporin 8 variant pro... 58 7e-08
AK222964-1|BAD96684.1| 261|Homo sapiens aquaporin 8 variant pro... 58 7e-08
AF067797-1|AAF19050.1| 261|Homo sapiens aquaporin 8 protein. 58 7e-08
AB013456-1|BAA34223.1| 261|Homo sapiens aquaporin 8 protein. 58 7e-08
AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein. 39 0.043
AC004691-1|AAC16481.1| 128|Homo sapiens unknown protein. 39 0.043
AB209156-1|BAD92393.1| 219|Homo sapiens aquaporin 4 isoform a v... 38 0.075
BC011876-1|AAH11876.1| 403|Homo sapiens ARFGAP1 protein protein. 33 2.1
BC006085-1|AAH06085.1| 403|Homo sapiens ARFGAP1 protein protein. 33 2.1
BC000786-1|AAH00786.1| 403|Homo sapiens ARFGAP1 protein protein. 33 2.1
X07384-1|CAA30297.1| 1106|Homo sapiens protein ( Human mRNA for ... 31 6.5
BC013000-1|AAH13000.1| 1106|Homo sapiens glioma-associated oncog... 31 6.5
AF316573-1|AAM13391.1| 1106|Homo sapiens GLI1 protein. 31 6.5
>U36308-1|AAC02794.2| 263|Homo sapiens lens major intrinsic protein
protein.
Length = 263
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/176 (34%), Positives = 74/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P PL A+A G + LVQ + HISGA +NP VT A +V ++S +RA
Sbjct: 36 PGPLHVLQVAMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLL 95
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
L P VS +A VE L L A +D R
Sbjct: 96 GAVAGAAVLYSVTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNG 155
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
S L +G S+A L TGA MNPAR P +L G F + WVY VGP G
Sbjct: 156 QLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIG 211
>BC117474-1|AAI17475.1| 263|Homo sapiens major intrinsic protein of
lens fiber protein.
Length = 263
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/176 (34%), Positives = 74/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P PL A+A G + LVQ + HISGA +NP VT A +V ++S +RA
Sbjct: 36 PGPLHVLQVAMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLL 95
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
L P VS +A VE L L A +D R
Sbjct: 96 GAVAGAAVLYSVTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNG 155
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
S L +G S+A L TGA MNPAR P +L G F + WVY VGP G
Sbjct: 156 QLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIG 211
>BC074913-1|AAH74913.1| 263|Homo sapiens major intrinsic protein of
lens fiber protein.
Length = 263
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/176 (34%), Positives = 74/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P PL A+A G + LVQ + HISGA +NP VT A +V ++S +RA
Sbjct: 36 PGPLHVLQVAMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLL 95
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
L P VS +A VE L L A +D R
Sbjct: 96 GAVAGAAVLYSVTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNG 155
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
S L +G S+A L TGA MNPAR P +L G F + WVY VGP G
Sbjct: 156 QLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIG 211
>AF000143-1|AAC03168.1| 263|Homo sapiens putative alternative lens
membrane intrinsic protein protein.
Length = 263
Score = 88.2 bits (209), Expect = 5e-17
Identities = 59/176 (33%), Positives = 72/176 (40%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P PL ALA G + LVQ + HISGA +NP VT A +V ++S +RA
Sbjct: 36 PGPLHVLQVALAFGLALATLVQTVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYIAAQLL 95
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
L GVS +A VE L L A +D R
Sbjct: 96 GAVAGAAVLYSVTPPAVRGNLALNTLHAGVSVGQATTVEIFLTLQFVLCIFATYDERRNG 155
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
S L +G S+ L TGA MNPAR P +L F + WVY VGP G
Sbjct: 156 RMGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFSNHWVYWVGPIIG 211
>Z29491-1|CAA82627.1| 271|Homo sapiens water channel aquaporin-2
protein.
Length = 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/181 (33%), Positives = 78/181 (43%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P LP+ L A+A G + LVQ L HISGA +NP VT+A +V VS +RA
Sbjct: 34 WPQALPSVLQ---IAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYV 90
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + + +AV VE L L L A+ D
Sbjct: 91 AAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD 150
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
R + L IG SVA L+ TG MNPAR L P V+ G F WV+ +GP
Sbjct: 151 ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLV 210
Query: 762 G 764
G
Sbjct: 211 G 211
>D31846-1|BAA06632.1| 271|Homo sapiens human aquaporin-2 water
channel protein.
Length = 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/181 (33%), Positives = 78/181 (43%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P LP+ L A+A G + LVQ L HISGA +NP VT+A +V VS +RA
Sbjct: 34 WPQALPSVLQ---IAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYV 90
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + + +AV VE L L L A+ D
Sbjct: 91 AAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD 150
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
R + L IG SVA L+ TG MNPAR L P V+ G F WV+ +GP
Sbjct: 151 ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLV 210
Query: 762 G 764
G
Sbjct: 211 G 211
>BC042496-1|AAH42496.1| 271|Homo sapiens aquaporin 2 (collecting
duct) protein.
Length = 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/181 (33%), Positives = 78/181 (43%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P LP+ L A+A G + LVQ L HISGA +NP VT+A +V VS +RA
Sbjct: 34 WPQALPSVLQ---IAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYV 90
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + + +AV VE L L L A+ D
Sbjct: 91 AAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD 150
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
R + L IG SVA L+ TG MNPAR L P V+ G F WV+ +GP
Sbjct: 151 ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLV 210
Query: 762 G 764
G
Sbjct: 211 G 211
>AF147093-1|AAD38692.1| 271|Homo sapiens aquaporin 2 protein.
Length = 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/181 (33%), Positives = 78/181 (43%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P LP+ L A+A G + LVQ L HISGA +NP VT+A +V VS +RA
Sbjct: 34 WPQALPSVLQ---IAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYV 90
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + + +AV VE L L L A+ D
Sbjct: 91 AAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD 150
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
R + L IG SVA L+ TG MNPAR L P V+ G F WV+ +GP
Sbjct: 151 ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLV 210
Query: 762 G 764
G
Sbjct: 211 G 211
>CR542024-1|CAG46821.1| 271|Homo sapiens AQP2 protein.
Length = 271
Score = 81.0 bits (191), Expect = 8e-15
Identities = 59/181 (32%), Positives = 77/181 (42%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P LP+ L A+A G + VQ L HISGA +NP VT+A +V VS +RA
Sbjct: 34 WPQALPSVLQ---IAMAFGLGIGTRVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYV 90
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + + +AV VE L L L A+ D
Sbjct: 91 AAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD 150
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
R + L IG SVA L+ TG MNPAR L P V+ G F WV+ +GP
Sbjct: 151 ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLV 210
Query: 762 G 764
G
Sbjct: 211 G 211
>S73197-1|AAB31998.1| 271|Homo sapiens water-channel aquaporin 2
protein.
Length = 271
Score = 80.2 bits (189), Expect = 1e-14
Identities = 59/181 (32%), Positives = 77/181 (42%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P LP+ L A+A G + LVQ L HIS A +NP VT+A +V VS +RA
Sbjct: 34 WPQALPSVLQ---IAMAFGLGIGTLVQALGHISRAHINPAVTVACLVGCHVSVLRAAFYV 90
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + + +AV VE L L L A+ D
Sbjct: 91 AAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD 150
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
R + L IG SVA L+ TG MNPAR L P V+ G F WV+ +GP
Sbjct: 151 ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLV 210
Query: 762 G 764
G
Sbjct: 211 G 211
>S73196-1|AAB31999.1| 271|Homo sapiens water-channel aquaporin 2
protein.
Length = 271
Score = 80.2 bits (189), Expect = 1e-14
Identities = 59/181 (32%), Positives = 77/181 (42%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P LP+ L A+A G + LVQ L HISGA +NP VT+A +V VS +RA
Sbjct: 34 WPQALPSVLQ---IAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYV 90
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + + +AV VE L L L A+ D
Sbjct: 91 AAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD 150
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
R + L IG SVA L+ TG MNPA L P V+ G F WV+ +GP
Sbjct: 151 ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPACSLAPAVVTGKFDDHWVFWIGPLV 210
Query: 762 G 764
G
Sbjct: 211 G 211
>AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a
variant protein.
Length = 323
Score = 80.2 bits (189), Expect = 1e-14
Identities = 49/176 (27%), Positives = 75/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 65 PLPIDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL 124
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
+T+ ++ + VE ++ L A+ D +
Sbjct: 125 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD 184
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+ S L IG SVA L A TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 185 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 240
>U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein.
Length = 301
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/176 (27%), Positives = 75/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 43 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL 102
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
+T+ ++ + VE ++ L A+ D +
Sbjct: 103 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD 162
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+ S L IG SVA L A TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 163 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 218
>U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/176 (27%), Positives = 75/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 65 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL 124
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
+T+ ++ + VE ++ L A+ D +
Sbjct: 125 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD 184
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+ S L IG SVA L A TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 185 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 240
>U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive water
channel protein.
Length = 341
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/176 (27%), Positives = 75/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 83 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL 142
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
+T+ ++ + VE ++ L A+ D +
Sbjct: 143 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD 202
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+ S L IG SVA L A TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 203 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 258
>U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive water
channel protein.
Length = 301
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/176 (27%), Positives = 75/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 43 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL 102
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
+T+ ++ + VE ++ L A+ D +
Sbjct: 103 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD 162
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+ S L IG SVA L A TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 163 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 218
>D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein.
Length = 323
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/176 (27%), Positives = 75/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 65 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL 124
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
+T+ ++ + VE ++ L A+ D +
Sbjct: 125 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD 184
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+ S L IG SVA L A TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 185 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 240
>BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/176 (27%), Positives = 75/176 (42%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXX 416
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 65 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL 124
Query: 417 XXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQH 596
+T+ ++ + VE ++ L A+ D +
Sbjct: 125 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD 184
Query: 597 LRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+ S L IG SVA L A TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 185 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 240
>BC022486-1|AAH22486.1| 269|Homo sapiens aquaporin 1 (Colton blood
group) protein.
Length = 269
Score = 78.2 bits (184), Expect = 6e-14
Identities = 52/175 (29%), Positives = 76/175 (43%)
Frame = +3
Query: 240 TPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXX 419
T + +LA G + L Q + HISGA +NP VTL ++ ++S RA++
Sbjct: 45 TVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVG 104
Query: 420 XXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHL 599
A GV++ + + +E + L L A D R + L
Sbjct: 105 AIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDL 164
Query: 600 RDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
S PL IG SVA L+A TG +NPAR V+ F + W++ VGP G
Sbjct: 165 GGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG 219
>U41517-1|AAC50648.1| 269|Homo sapiens channel-like integral
membrane protein protein.
Length = 269
Score = 77.8 bits (183), Expect = 8e-14
Identities = 51/167 (30%), Positives = 74/167 (44%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
+LA G + L Q + HISGA +NP VTL ++ ++S RA++
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 444 XXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRI 623
A GV++ + + +E + L L A D R + L S PL I
Sbjct: 113 SGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAI 172
Query: 624 GTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
G SVA L+A TG +NPAR V+ F + W++ VGP G
Sbjct: 173 GLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG 219
>S73482-1|AAB31193.1| 269|Homo sapiens uterine water channel
protein.
Length = 269
Score = 77.8 bits (183), Expect = 8e-14
Identities = 51/167 (30%), Positives = 74/167 (44%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
+LA G + L Q + HISGA +NP VTL ++ ++S RA++
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 444 XXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRI 623
A GV++ + + +E + L L A D R + L S PL I
Sbjct: 113 SGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAI 172
Query: 624 GTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
G SVA L+A TG +NPAR V+ F + W++ VGP G
Sbjct: 173 GLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG 219
>M77829-1|AAA58425.1| 269|Homo sapiens channel-like integral
membrane protein protein.
Length = 269
Score = 77.8 bits (183), Expect = 8e-14
Identities = 51/167 (30%), Positives = 74/167 (44%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
+LA G + L Q + HISGA +NP VTL ++ ++S RA++
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 444 XXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRI 623
A GV++ + + +E + L L A D R + L S PL I
Sbjct: 113 SGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAI 172
Query: 624 GTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
G SVA L+A TG +NPAR V+ F + W++ VGP G
Sbjct: 173 GLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG 219
>AY953319-1|AAX24129.1| 269|Homo sapiens aquaporin 1
(channel-forming integral protein, 28kDa) protein.
Length = 269
Score = 77.8 bits (183), Expect = 8e-14
Identities = 51/167 (30%), Positives = 74/167 (44%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
+LA G + L Q + HISGA +NP VTL ++ ++S RA++
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 444 XXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRI 623
A GV++ + + +E + L L A D R + L S PL I
Sbjct: 113 SGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAI 172
Query: 624 GTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
G SVA L+A TG +NPAR V+ F + W++ VGP G
Sbjct: 173 GLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG 219
>AF480415-1|AAL87136.1| 265|Homo sapiens aquaporin 1 protein.
Length = 265
Score = 77.8 bits (183), Expect = 8e-14
Identities = 51/167 (30%), Positives = 74/167 (44%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
+LA G + L Q + HISGA +NP VTL ++ ++S RA++
Sbjct: 49 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 108
Query: 444 XXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRI 623
A GV++ + + +E + L L A D R + L S PL I
Sbjct: 109 SGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAI 168
Query: 624 GTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
G SVA L+A TG +NPAR V+ F + W++ VGP G
Sbjct: 169 GLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG 215
>U46569-1|AAC50474.1| 265|Homo sapiens aquaporin-5 protein.
Length = 265
Score = 76.2 bits (179), Expect = 2e-13
Identities = 58/182 (31%), Positives = 76/182 (41%), Gaps = 1/182 (0%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+PS LPT L ALA G + L Q L +SG +NP +TLA +V ++S +RA
Sbjct: 35 WPSALPTILQ---IALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYV 91
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + +A+ VE +L LAL A+ D
Sbjct: 92 AAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTD 151
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFH-HXWVYXVGPX 758
R S L IG SV LV TG MNPAR P V++ F WV+ VGP
Sbjct: 152 SRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPI 211
Query: 759 XG 764
G
Sbjct: 212 VG 213
>CR542022-1|CAG46819.1| 265|Homo sapiens AQP5 protein.
Length = 265
Score = 76.2 bits (179), Expect = 2e-13
Identities = 58/182 (31%), Positives = 76/182 (41%), Gaps = 1/182 (0%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+PS LPT L ALA G + L Q L +SG +NP +TLA +V ++S +RA
Sbjct: 35 WPSALPTILQ---IALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYV 91
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + +A+ VE +L LAL A+ D
Sbjct: 92 AAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTD 151
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFH-HXWVYXVGPX 758
R S L IG SV LV TG MNPAR P V++ F WV+ VGP
Sbjct: 152 SRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPI 211
Query: 759 XG 764
G
Sbjct: 212 VG 213
>CR541989-1|CAG46786.1| 265|Homo sapiens AQP5 protein.
Length = 265
Score = 76.2 bits (179), Expect = 2e-13
Identities = 58/182 (31%), Positives = 76/182 (41%), Gaps = 1/182 (0%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+PS LPT L ALA G + L Q L +SG +NP +TLA +V ++S +RA
Sbjct: 35 WPSALPTILQ---IALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYV 91
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + +A+ VE +L LAL A+ D
Sbjct: 92 AAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTD 151
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFH-HXWVYXVGPX 758
R S L IG SV LV TG MNPAR P V++ F WV+ VGP
Sbjct: 152 SRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPI 211
Query: 759 XG 764
G
Sbjct: 212 VG 213
>BC032946-1|AAH32946.1| 265|Homo sapiens aquaporin 5 protein.
Length = 265
Score = 76.2 bits (179), Expect = 2e-13
Identities = 58/182 (31%), Positives = 76/182 (41%), Gaps = 1/182 (0%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+PS LPT L ALA G + L Q L +SG +NP +TLA +V ++S +RA
Sbjct: 35 WPSALPTILQ---IALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYV 91
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ + +A+ VE +L LAL A+ D
Sbjct: 92 AAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTD 151
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFH-HXWVYXVGPX 758
R S L IG SV LV TG MNPAR P V++ F WV+ VGP
Sbjct: 152 SRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPI 211
Query: 759 XG 764
G
Sbjct: 212 VG 213
>U48408-1|AAB41566.1| 282|Homo sapiens water channel protein.
Length = 282
Score = 75.4 bits (177), Expect = 4e-13
Identities = 58/181 (32%), Positives = 75/181 (41%)
Frame = +3
Query: 222 FPSCLPTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMF 401
+P+ LP+ L A+ V M VQ SGA NP VTLA +V +S RA+
Sbjct: 48 WPTALPSVLQ---IAITFNLVTAMAVQVTWKTSGAHANPAVTLAFLVGSHISLPRAVAYV 104
Query: 402 XXXXXXXXXXXXXXXXXXXXXXXXXXCLTVPAPGVSTARAVAVEAVLGACLALVNCAAWD 581
+ V VST +AVAVE +L L LV C
Sbjct: 105 AAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLL--TLQLVLCVFAS 162
Query: 582 PRNQHLRDSWPLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXX 761
++ S IG S A L+ TG MNPAR P +++G F WV+ VGP
Sbjct: 163 TDSRQTSGSPATMIGISWALGHLIGILFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLM 222
Query: 762 G 764
G
Sbjct: 223 G 223
>U41518-1|AAC50649.1| 152|Homo sapiens channel-like integral
membrane protein protein.
Length = 152
Score = 58.4 bits (135), Expect = 5e-08
Identities = 33/90 (36%), Positives = 46/90 (51%)
Frame = +3
Query: 495 APGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRIGTSVAAMSLVAGTLTGA 674
A GV++ + + +E + L L A D R + L S PL IG SVA L+A TG
Sbjct: 13 ADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGC 72
Query: 675 XMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+NPAR V+ F + W++ VGP G
Sbjct: 73 GINPARSFGSAVITHNFSNHWIFWVGPFIG 102
>AC005155-1|AAC23788.1| 141|Homo sapiens aquaporin protein.
Length = 141
Score = 58.4 bits (135), Expect = 5e-08
Identities = 33/90 (36%), Positives = 46/90 (51%)
Frame = +3
Query: 495 APGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRIGTSVAAMSLVAGTLTGA 674
A GV++ + + +E + L L A D R + L S PL IG SVA L+A TG
Sbjct: 2 ADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGC 61
Query: 675 XMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
+NPAR V+ F + W++ VGP G
Sbjct: 62 GINPARSFGSAVITHNFSNHWIFWVGPFIG 91
>AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcript
variant c protein.
Length = 218
Score = 58.4 bits (135), Expect = 5e-08
Identities = 32/94 (34%), Positives = 47/94 (50%)
Frame = +3
Query: 483 LTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSWPLRIGTSVAAMSLVAGT 662
+T+ ++ + VE ++ L A+ D + + S L IG SVA L A
Sbjct: 42 VTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAIN 101
Query: 663 LTGAXMNPARXLXPXVLLGXFHHXWVYXVGPXXG 764
TGA MNPAR P V++G + + W+Y VGP G
Sbjct: 102 YTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG 135
>BC040630-1|AAH40630.1| 255|Homo sapiens AQP8 protein protein.
Length = 255
Score = 58.0 bits (134), Expect = 7e-08
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 5/169 (2%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
ALA G + +++ L +ISG NP V+LAA++ G ++ V + +
Sbjct: 63 ALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALA 122
Query: 444 XXXXXXXXXXXXC----LTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSW 611
+TV G A A+ E +L LAL C N+ +
Sbjct: 123 KAVSPEERFWNASGAAFVTVQEQG-QVAGALVAEIILTTLLALAVCMG--AINEKTKGPL 179
Query: 612 -PLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGP 755
P IG +V L G ++G MNPAR P V+ ++ W+Y +GP
Sbjct: 180 APFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGP 228
>AK222975-1|BAD96695.1| 261|Homo sapiens aquaporin 8 variant
protein.
Length = 261
Score = 58.0 bits (134), Expect = 7e-08
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 5/169 (2%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
ALA G + +++ L +ISG NP V+LAA++ G ++ V + +
Sbjct: 69 ALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALA 128
Query: 444 XXXXXXXXXXXXC----LTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSW 611
+TV G A A+ E +L LAL C N+ +
Sbjct: 129 KAVSPEERFWNASGAAFVTVQEQG-QVAGALVAEIILTTLLALAVCMG--AINEKTKGPL 185
Query: 612 -PLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGP 755
P IG +V L G ++G MNPAR P V+ ++ W+Y +GP
Sbjct: 186 APFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGP 234
>AK222964-1|BAD96684.1| 261|Homo sapiens aquaporin 8 variant
protein.
Length = 261
Score = 58.0 bits (134), Expect = 7e-08
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 5/169 (2%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
ALA G + +++ L +ISG NP V+LAA++ G ++ V + +
Sbjct: 69 ALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALA 128
Query: 444 XXXXXXXXXXXXC----LTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSW 611
+TV G A A+ E +L LAL C N+ +
Sbjct: 129 KAVSPEERFWNASGAAFVTVQEQG-QVAGALVAEIILTTLLALAVCMG--AINEKTKGPL 185
Query: 612 -PLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGP 755
P IG +V L G ++G MNPAR P V+ ++ W+Y +GP
Sbjct: 186 APFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGP 234
>AF067797-1|AAF19050.1| 261|Homo sapiens aquaporin 8 protein.
Length = 261
Score = 58.0 bits (134), Expect = 7e-08
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 5/169 (2%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
ALA G + +++ L +ISG NP V+LAA++ G ++ V + +
Sbjct: 69 ALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALA 128
Query: 444 XXXXXXXXXXXXC----LTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSW 611
+TV G A A+ E +L LAL C N+ +
Sbjct: 129 KAVSPEERFWNASGAAFVTVQEQG-QVAGALVAEIILTTLLALAVCMG--AINEKTKGPL 185
Query: 612 -PLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGP 755
P IG +V L G ++G MNPAR P V+ ++ W+Y +GP
Sbjct: 186 APFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGP 234
>AB013456-1|BAA34223.1| 261|Homo sapiens aquaporin 8 protein.
Length = 261
Score = 58.0 bits (134), Expect = 7e-08
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 5/169 (2%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIVMFXXXXXXXXXXXXXX 443
ALA G + +++ L +ISG NP V+LAA++ G ++ V + +
Sbjct: 69 ALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALA 128
Query: 444 XXXXXXXXXXXXC----LTVPAPGVSTARAVAVEAVLGACLALVNCAAWDPRNQHLRDSW 611
+TV G A A+ E +L LAL C N+ +
Sbjct: 129 KVVSPEERFWNASGAAFVTVQEQG-QVAGALVAEIILTTLLALAVCMG--AINEKTKGPL 185
Query: 612 -PLRIGTSVAAMSLVAGTLTGAXMNPARXLXPXVLLGXFHHXWVYXVGP 755
P IG +V L G ++G MNPAR P V+ ++ W+Y +GP
Sbjct: 186 APFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGP 234
>AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.
Length = 4061
Score = 38.7 bits (86), Expect = 0.043
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 2/120 (1%)
Frame = -3
Query: 464 ARRYQRGQSRGARCSARQLCREHHDRAHRRHPTPHHGCQXXXXXXXXXRDVIQALNQHSD 285
+ R+ SR R SA++ R+ RHPT HH + Q+ H++
Sbjct: 3552 SERWSGSASRNHRGSAQEQSRDGS-----RHPTSHH--EDRAGHGHSAESSRQSGTHHAE 3604
Query: 284 NTTAGERSVRGAERRGQTGWKTREQHEQS--SAQRLGCGHARQLRPIVGRQSRGAAAPAA 111
N++ G+ + + R G + H+QS S++ G GH + + RG++ A
Sbjct: 3605 NSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA 3664
>AC004691-1|AAC16481.1| 128|Homo sapiens unknown protein.
Length = 128
Score = 38.7 bits (86), Expect = 0.043
Identities = 18/44 (40%), Positives = 28/44 (63%)
Frame = +3
Query: 264 ALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAIV 395
+LA G + L Q + HISGA +NP VTL ++ ++S RA++
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALM 96
>AB209156-1|BAD92393.1| 219|Homo sapiens aquaporin 4 isoform a
variant protein.
Length = 219
Score = 37.9 bits (84), Expect = 0.075
Identities = 17/52 (32%), Positives = 28/52 (53%)
Frame = +3
Query: 237 PTPLSSTHTALASGCVVTMLVQGLDHISGAMMNPTVTLAAVVWGRVSAVRAI 392
P P+ +L G + +VQ HISG +NP VT+A V ++S +++
Sbjct: 72 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSV 123
>BC011876-1|AAH11876.1| 403|Homo sapiens ARFGAP1 protein protein.
Length = 403
Score = 33.1 bits (72), Expect = 2.1
Identities = 17/36 (47%), Positives = 22/36 (61%)
Frame = +2
Query: 218 VFSILSAHASQLHAHCARQRLCCHYAGSGLGSHLGR 325
+F +S+ SQL + C R RLCCH + G HLGR
Sbjct: 264 IFDDVSSGVSQLASKCQR-RLCCHQSHCSAG-HLGR 297
>BC006085-1|AAH06085.1| 403|Homo sapiens ARFGAP1 protein protein.
Length = 403
Score = 33.1 bits (72), Expect = 2.1
Identities = 17/36 (47%), Positives = 22/36 (61%)
Frame = +2
Query: 218 VFSILSAHASQLHAHCARQRLCCHYAGSGLGSHLGR 325
+F +S+ SQL + C R RLCCH + G HLGR
Sbjct: 264 IFDDVSSGVSQLASKCQR-RLCCHQSHCSAG-HLGR 297
>BC000786-1|AAH00786.1| 403|Homo sapiens ARFGAP1 protein protein.
Length = 403
Score = 33.1 bits (72), Expect = 2.1
Identities = 17/36 (47%), Positives = 22/36 (61%)
Frame = +2
Query: 218 VFSILSAHASQLHAHCARQRLCCHYAGSGLGSHLGR 325
+F +S+ SQL + C R RLCCH + G HLGR
Sbjct: 264 IFDDVSSGVSQLASKCQR-RLCCHQSHCSAG-HLGR 297
>X07384-1|CAA30297.1| 1106|Homo sapiens protein ( Human mRNA for GLI
protein. ).
Length = 1106
Score = 31.5 bits (68), Expect = 6.5
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = -2
Query: 732 GDGXAPIRPRGXXXGPGSXWRPSACPQQGTWPPRTCRS-GAAMSHAGV 592
G G P+ P GP + + P+ CPQQ ++P T + G SH+G+
Sbjct: 747 GPGSLPLGP-----GPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGL 789
>BC013000-1|AAH13000.1| 1106|Homo sapiens glioma-associated oncogene
homolog 1 (zinc finger protein) protein.
Length = 1106
Score = 31.5 bits (68), Expect = 6.5
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = -2
Query: 732 GDGXAPIRPRGXXXGPGSXWRPSACPQQGTWPPRTCRS-GAAMSHAGV 592
G G P+ P GP + + P+ CPQQ ++P T + G SH+G+
Sbjct: 747 GPGSLPLGP-----GPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGL 789
>AF316573-1|AAM13391.1| 1106|Homo sapiens GLI1 protein.
Length = 1106
Score = 31.5 bits (68), Expect = 6.5
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = -2
Query: 732 GDGXAPIRPRGXXXGPGSXWRPSACPQQGTWPPRTCRS-GAAMSHAGV 592
G G P+ P GP + + P+ CPQQ ++P T + G SH+G+
Sbjct: 747 GPGSLPLGP-----GPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGL 789
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,008,075
Number of Sequences: 237096
Number of extensions: 2222210
Number of successful extensions: 10223
Number of sequences better than 10.0: 46
Number of HSP's better than 10.0 without gapping: 9019
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10179
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17504701140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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