Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_E18
(1247 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY515706-1|AAR99656.1| 668|Homo sapiens bestrophin 3 protein. 227 9e-59
AK096459-1|BAC04797.1| 668|Homo sapiens protein ( Homo sapiens ... 227 9e-59
AF440758-1|AAM76997.1| 398|Homo sapiens vitelliform macular dys... 227 9e-59
BC101823-1|AAI01824.1| 473|Homo sapiens bestrophin 4 protein. 225 3e-58
AY515707-1|AAR99657.1| 473|Homo sapiens bestrophin 4 protein. 225 3e-58
AL592166-10|CAI13005.1| 473|Homo sapiens vitelliform macular dy... 225 3e-58
AF440757-1|AAM76996.1| 473|Homo sapiens vitelliform macular dys... 225 3e-58
AY515705-1|AAR99655.1| 509|Homo sapiens bestrophin 2 protein. 219 1e-56
AF440756-1|AAM76995.1| 509|Homo sapiens vitelliform macular dys... 219 1e-56
AY515704-1|AAR99654.1| 585|Homo sapiens bestrophin 1 protein. 212 2e-54
AF073501-1|AAC33766.1| 585|Homo sapiens vitelliform macular dys... 212 2e-54
AF073500-1|AAC64926.1| 585|Homo sapiens vitelliform macular dys... 212 2e-54
AF057170-1|AAC64344.1| 435|Homo sapiens bestrophin protein. 212 2e-54
AF057169-1|AAC64343.1| 585|Homo sapiens bestrophin protein. 212 2e-54
AK000139-1|BAA90970.1| 466|Homo sapiens protein ( Homo sapiens ... 184 5e-46
BC041664-1|AAH41664.1| 604|Homo sapiens BEST1 protein protein. 169 1e-41
BC015220-1|AAH15220.1| 498|Homo sapiens BEST1 protein protein. 169 1e-41
AB209451-1|BAD92688.1| 376|Homo sapiens bestrophin variant prot... 151 7e-36
BC006440-1|AAH06440.1| 72|Homo sapiens BEST3 protein protein. 52 3e-06
X86098-1|CAA60052.1| 562|Homo sapiens BS69 protein. 31 6.6
DQ335455-1|ABC72411.1| 568|Homo sapiens BS69 variant 4 protein. 31 6.6
DQ335454-1|ABC72410.1| 514|Homo sapiens BS69 variant 3 protein. 31 6.6
DQ335453-1|ABC72409.1| 548|Homo sapiens BS69 variant 2 protein. 31 6.6
DQ335452-1|ABC72408.1| 602|Homo sapiens BS69 variant 1 protein. 31 6.6
BC091489-1|AAH91489.1| 508|Homo sapiens ZMYND11 protein protein. 31 6.6
BC034784-1|AAH34784.1| 527|Homo sapiens zinc finger, MYND domai... 31 6.6
AY732489-1|AAV33128.1| 482|Homo sapiens zinc finger MYND domain... 31 6.6
AL603831-2|CAI40899.1| 562|Homo sapiens adenovirus 5 E1A bindin... 31 6.6
AL589988-2|CAH69846.1| 528|Homo sapiens adenovirus 5 E1A bindin... 31 6.6
AL589988-1|CAH69845.1| 562|Homo sapiens adenovirus 5 E1A bindin... 31 6.6
>AY515706-1|AAR99656.1| 668|Homo sapiens bestrophin 3 protein.
Length = 668
Score = 227 bits (554), Expect = 9e-59
Identities = 111/251 (44%), Positives = 152/251 (60%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT++Y+ +V N + FG F R+L KWRGS+YKL++RE R LT Q+
Sbjct: 1 MTVTYSSKVANATFFG-FHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQK 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
R FEK+ Y +E IP++FVLGFYV+LVV RWW Q+ LPWPD L IS+ + G+DE
Sbjct: 60 RYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RY L ++ + VS V +RFPT HVV++G M ERK+F + KSP
Sbjct: 120 HGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHL--KSP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
KYW+P +W N+ +AR EG I +Q+ + E++ L GYD +PLVYT
Sbjct: 178 HLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VTL+ F
Sbjct: 238 QVVTLAVYTFF 248
>AK096459-1|BAC04797.1| 668|Homo sapiens protein ( Homo sapiens cDNA
FLJ39140 fis, clone NTONG2009233, moderately similar to
BESTROPHIN. ).
Length = 668
Score = 227 bits (554), Expect = 9e-59
Identities = 111/251 (44%), Positives = 152/251 (60%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT++Y+ +V N + FG F R+L KWRGS+YKL++RE R LT Q+
Sbjct: 1 MTVTYSSKVANATFFG-FHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQK 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
R FEK+ Y +E IP++FVLGFYV+LVV RWW Q+ LPWPD L IS+ + G+DE
Sbjct: 60 RYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RY L ++ + VS V +RFPT HVV++G M ERK+F + KSP
Sbjct: 120 HGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHL--KSP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
KYW+P +W N+ +AR EG I +Q+ + E++ L GYD +PLVYT
Sbjct: 178 HLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VTL+ F
Sbjct: 238 QVVTLAVYTFF 248
>AF440758-1|AAM76997.1| 398|Homo sapiens vitelliform macular
dystrophy 2-like protein 3 protein.
Length = 398
Score = 227 bits (554), Expect = 9e-59
Identities = 111/251 (44%), Positives = 152/251 (60%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT++Y+ +V N + FG F R+L KWRGS+YKL++RE R LT Q+
Sbjct: 1 MTVTYSSKVANATFFG-FHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQK 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
R FEK+ Y +E IP++FVLGFYV+LVV RWW Q+ LPWPD L IS+ + G+DE
Sbjct: 60 RYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RY L ++ + VS V +RFPT HVV++G M ERK+F + KSP
Sbjct: 120 HGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHL--KSP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
KYW+P +W N+ +AR EG I +Q+ + E++ L GYD +PLVYT
Sbjct: 178 HLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VTL+ F
Sbjct: 238 QVVTLAVYTFF 248
>BC101823-1|AAI01824.1| 473|Homo sapiens bestrophin 4 protein.
Length = 473
Score = 225 bits (549), Expect = 3e-58
Identities = 112/251 (44%), Positives = 155/251 (61%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT+SY +V + FG F +L +WRGS+YKL+++E R LT++Q+
Sbjct: 1 MTVSYTLKVAE-ARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQR 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
V+ +V +Y ++ IP+SFVLGFYV+LVV RWW QY +P PD L ISA + G D+
Sbjct: 60 YVYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQ 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA LA V+ L+ VS RV +RFPT +HVVD+G M + ERK FE + KS
Sbjct: 120 RGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESL--KSD 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+KYW+P VW TN+ +AR++G I D + L EL+ L YD +PLVYT
Sbjct: 178 FNKYWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTIAVYSFF 248
>AY515707-1|AAR99657.1| 473|Homo sapiens bestrophin 4 protein.
Length = 473
Score = 225 bits (549), Expect = 3e-58
Identities = 112/251 (44%), Positives = 155/251 (61%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT+SY +V + FG F +L +WRGS+YKL+++E R LT++Q+
Sbjct: 1 MTVSYTLKVAE-ARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQR 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
V+ +V +Y ++ IP+SFVLGFYV+LVV RWW QY +P PD L ISA + G D+
Sbjct: 60 YVYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQ 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA LA V+ L+ VS RV +RFPT +HVVD+G M + ERK FE + KS
Sbjct: 120 RGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESL--KSD 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+KYW+P VW TN+ +AR++G I D + L EL+ L YD +PLVYT
Sbjct: 178 FNKYWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTIAVYSFF 248
>AL592166-10|CAI13005.1| 473|Homo sapiens vitelliform macular
dystrophy 2-like 2 protein.
Length = 473
Score = 225 bits (549), Expect = 3e-58
Identities = 112/251 (44%), Positives = 155/251 (61%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT+SY +V + FG F +L +WRGS+YKL+++E R LT++Q+
Sbjct: 1 MTVSYTLKVAE-ARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQR 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
V+ +V +Y ++ IP+SFVLGFYV+LVV RWW QY +P PD L ISA + G D+
Sbjct: 60 YVYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQ 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA LA V+ L+ VS RV +RFPT +HVVD+G M + ERK FE + KS
Sbjct: 120 RGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESL--KSD 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+KYW+P VW TN+ +AR++G I D + L EL+ L YD +PLVYT
Sbjct: 178 FNKYWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTIAVYSFF 248
>AF440757-1|AAM76996.1| 473|Homo sapiens vitelliform macular
dystrophy 2-like protein 2 protein.
Length = 473
Score = 225 bits (549), Expect = 3e-58
Identities = 112/251 (44%), Positives = 155/251 (61%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT+SY +V + FG F +L +WRGS+YKL+++E R LT++Q+
Sbjct: 1 MTVSYTLKVAE-ARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQR 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
V+ +V +Y ++ IP+SFVLGFYV+LVV RWW QY +P PD L ISA + G D+
Sbjct: 60 YVYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQ 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA LA V+ L+ VS RV +RFPT +HVVD+G M + ERK FE + KS
Sbjct: 120 RGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESL--KSD 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+KYW+P VW TN+ +AR++G I D + L EL+ L YD +PLVYT
Sbjct: 178 FNKYWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTIAVYSFF 248
>AY515705-1|AAR99655.1| 509|Homo sapiens bestrophin 2 protein.
Length = 509
Score = 219 bits (536), Expect = 1e-56
Identities = 112/251 (44%), Positives = 151/251 (60%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT++Y V N + FG F ++L WRGS+YKL+WRE RF LTE Q+
Sbjct: 1 MTVTYTARVAN-ARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQK 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
R FEK+ Y + IP+SFVLGFYV+LVV RWW QY +P PD L ++ + G D+
Sbjct: 60 RYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDD 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL RR ++RYA L+ V+ L+ VS V +RFPT HVV++G M ERK FE ++ S
Sbjct: 120 RGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLN--SS 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+KYW+P VW +N+ +AR+EG I + ++ L EL+ G L YD VPLVYT
Sbjct: 178 YNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTIALYSYF 248
>AF440756-1|AAM76995.1| 509|Homo sapiens vitelliform macular
dystrophy 2-like protein 1 protein.
Length = 509
Score = 219 bits (536), Expect = 1e-56
Identities = 112/251 (44%), Positives = 151/251 (60%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MT++Y V N + FG F ++L WRGS+YKL+WRE RF LTE Q+
Sbjct: 1 MTVTYTARVAN-ARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQK 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
R FEK+ Y + IP+SFVLGFYV+LVV RWW QY +P PD L ++ + G D+
Sbjct: 60 RYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDD 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL RR ++RYA L+ V+ L+ VS V +RFPT HVV++G M ERK FE ++ S
Sbjct: 120 RGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLN--SS 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+KYW+P VW +N+ +AR+EG I + ++ L EL+ G L YD VPLVYT
Sbjct: 178 YNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTIALYSYF 248
>AY515704-1|AAR99654.1| 585|Homo sapiens bestrophin 1 protein.
Length = 585
Score = 212 bits (518), Expect = 2e-54
Identities = 108/251 (43%), Positives = 150/251 (59%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MTI+Y +V N + G F R+L WRGS+YKL++ E R ALTE+QQ
Sbjct: 1 MTITYTSQVAN-ARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQ 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S + G DE
Sbjct: 60 LMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA L V+ L+ VS V +RFP+ QH+V +G M +E K EK+ P
Sbjct: 120 QGRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+ +W+P VW N+ +A G I ++Q+ L E++ + G L YD +PLVYT
Sbjct: 178 HNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTVAVYSFF 248
>AF073501-1|AAC33766.1| 585|Homo sapiens vitelliform macular
dystrophy protein protein.
Length = 585
Score = 212 bits (518), Expect = 2e-54
Identities = 108/251 (43%), Positives = 150/251 (59%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MTI+Y +V N + G F R+L WRGS+YKL++ E R ALTE+QQ
Sbjct: 1 MTITYTSQVAN-ARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQ 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S + G DE
Sbjct: 60 LMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA L V+ L+ VS V +RFP+ QH+V +G M +E K EK+ P
Sbjct: 120 QGRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+ +W+P VW N+ +A G I ++Q+ L E++ + G L YD +PLVYT
Sbjct: 178 HNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTVAVYSFF 248
>AF073500-1|AAC64926.1| 585|Homo sapiens vitelliform macular
dystrophy protein protein.
Length = 585
Score = 212 bits (518), Expect = 2e-54
Identities = 108/251 (43%), Positives = 150/251 (59%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MTI+Y +V N + G F R+L WRGS+YKL++ E R ALTE+QQ
Sbjct: 1 MTITYTSQVAN-ARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQ 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S + G DE
Sbjct: 60 LMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA L V+ L+ VS V +RFP+ QH+V +G M +E K EK+ P
Sbjct: 120 QGRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+ +W+P VW N+ +A G I ++Q+ L E++ + G L YD +PLVYT
Sbjct: 178 HNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTVAVYSFF 248
>AF057170-1|AAC64344.1| 435|Homo sapiens bestrophin protein.
Length = 435
Score = 212 bits (518), Expect = 2e-54
Identities = 108/251 (43%), Positives = 150/251 (59%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MTI+Y +V N + G F R+L WRGS+YKL++ E R ALTE+QQ
Sbjct: 1 MTITYTSQVAN-ARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQ 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S + G DE
Sbjct: 60 LMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA L V+ L+ VS V +RFP+ QH+V +G M +E K EK+ P
Sbjct: 120 QGRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+ +W+P VW N+ +A G I ++Q+ L E++ + G L YD +PLVYT
Sbjct: 178 HNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTVAVYSFF 248
>AF057169-1|AAC64343.1| 585|Homo sapiens bestrophin protein.
Length = 585
Score = 212 bits (518), Expect = 2e-54
Identities = 108/251 (43%), Positives = 150/251 (59%)
Frame = +1
Query: 343 MTISYAGEVPNGSSFGCFWRILCKWRGSVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQ 522
MTI+Y +V N + G F R+L WRGS+YKL++ E R ALTE+QQ
Sbjct: 1 MTITYTSQVAN-ARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQ 59
Query: 523 RVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADE 702
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S + G DE
Sbjct: 60 LMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDE 119
Query: 703 TGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSP 882
GRL+RR ++RYA L V+ L+ VS V +RFP+ QH+V +G M +E K EK+ P
Sbjct: 120 QGRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLP 177
Query: 883 MSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYT 1062
+ +W+P VW N+ +A G I ++Q+ L E++ + G L YD +PLVYT
Sbjct: 178 HNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYT 237
Query: 1063 QXVTLSXVHLF 1095
Q VT++ F
Sbjct: 238 QVVTVAVYSFF 248
>AK000139-1|BAA90970.1| 466|Homo sapiens protein ( Homo sapiens cDNA
FLJ20132 fis, clone COL06441. ).
Length = 466
Score = 184 bits (449), Expect = 5e-46
Identities = 93/200 (46%), Positives = 125/200 (62%)
Frame = +1
Query: 496 RFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFI 675
RF LTE Q+R FEK+ Y + IP+SFVLGFYV+LVV RWW QY +P PD L +
Sbjct: 8 RFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVV 67
Query: 676 SAGIPGADETGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKV 855
+ + G D+ GRL RR ++RYA L+ V+ L+ VS V +RFPT HVV++G M ERK
Sbjct: 68 AGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKK 127
Query: 856 FEKMDGKSPMSKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYD 1035
FE ++ S +KYW+P VW +N+ +AR+EG I + ++ L EL+ G L YD
Sbjct: 128 FENLN--SSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYD 185
Query: 1036 TXCVPLVYTQXVTLSXVHLF 1095
VPLVYTQ VT++ F
Sbjct: 186 WISVPLVYTQVVTIALYSYF 205
>BC041664-1|AAH41664.1| 604|Homo sapiens BEST1 protein protein.
Length = 604
Score = 169 bits (412), Expect = 1e-41
Identities = 83/190 (43%), Positives = 117/190 (61%)
Frame = +1
Query: 526 VFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADET 705
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S + G DE
Sbjct: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60
Query: 706 GRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSPM 885
GRL+RR ++RYA L V+ L+ VS V +RFP+ QH+V +G M +E K EK+ P
Sbjct: 61 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLPH 118
Query: 886 SKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYTQ 1065
+ +W+P VW N+ +A G I ++Q+ L E++ + G L YD +PLVYTQ
Sbjct: 119 NMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQ 178
Query: 1066 XVTLSXVHLF 1095
VT++ F
Sbjct: 179 VVTVAVYSFF 188
>BC015220-1|AAH15220.1| 498|Homo sapiens BEST1 protein protein.
Length = 498
Score = 169 bits (412), Expect = 1e-41
Identities = 83/190 (43%), Positives = 117/190 (61%)
Frame = +1
Query: 526 VFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADET 705
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S + G DE
Sbjct: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60
Query: 706 GRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSPM 885
GRL+RR ++RYA L V+ L+ VS V +RFP+ QH+V +G M +E K EK+ P
Sbjct: 61 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLPH 118
Query: 886 SKYWMPLVWATNIINRARKEGLITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYTQ 1065
+ +W+P VW N+ +A G I ++Q+ L E++ + G L YD +PLVYTQ
Sbjct: 119 NMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQ 178
Query: 1066 XVTLSXVHLF 1095
VT++ F
Sbjct: 179 VVTVAVYSFF 188
>AB209451-1|BAD92688.1| 376|Homo sapiens bestrophin variant protein.
Length = 376
Score = 151 bits (365), Expect = 7e-36
Identities = 73/168 (43%), Positives = 102/168 (60%)
Frame = +1
Query: 592 GFYVSLVVKRWWEQYKLLPWPDTLALFISAGIPGADETGRLMRRNIVRYAILAYVITLQR 771
GFYV+LVV RWW QY+ LPWPD L +S + G DE GRL+RR ++RYA L V+ L+
Sbjct: 102 GFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRS 161
Query: 772 VSLRVKRRFPTWQHVVDSGLMLESERKVFEKMDGKSPMSKYWMPLVWATNIINRARKEGL 951
VS V +RFP+ QH+V +G M +E K EK+ P + +W+P VW N+ +A G
Sbjct: 162 VSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKL--SLPHNMFWVPWVWFANLSMKAWLGGR 219
Query: 952 ITSDHIVQTXLVELSDIXRXWGALMGYDTXCVPLVYTQXVTLSXVHLF 1095
I ++Q+ L E++ + G L YD +PLVYTQ VT++ F
Sbjct: 220 IRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFF 267
>BC006440-1|AAH06440.1| 72|Homo sapiens BEST3 protein protein.
Length = 72
Score = 52.4 bits (120), Expect = 3e-06
Identities = 23/51 (45%), Positives = 35/51 (68%)
Frame = +1
Query: 673 ISAGIPGADETGRLMRRNIVRYAILAYVITLQRVSLRVKRRFPTWQHVVDS 825
IS+ + G+DE GRL+RR ++RY L ++ + VS V +RFPT HVV++
Sbjct: 4 ISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEA 54
>X86098-1|CAA60052.1| 562|Homo sapiens BS69 protein.
Length = 562
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 385 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 437
>DQ335455-1|ABC72411.1| 568|Homo sapiens BS69 variant 4 protein.
Length = 568
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 425 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 477
>DQ335454-1|ABC72410.1| 514|Homo sapiens BS69 variant 3 protein.
Length = 514
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 371 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 423
>DQ335453-1|ABC72409.1| 548|Homo sapiens BS69 variant 2 protein.
Length = 548
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 371 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 423
>DQ335452-1|ABC72408.1| 602|Homo sapiens BS69 variant 1 protein.
Length = 602
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 425 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 477
>BC091489-1|AAH91489.1| 508|Homo sapiens ZMYND11 protein protein.
Length = 508
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 331 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 383
>BC034784-1|AAH34784.1| 527|Homo sapiens zinc finger, MYND domain
containing 11 protein.
Length = 527
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 384 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 436
>AY732489-1|AAV33128.1| 482|Homo sapiens zinc finger MYND domain
containing 11 transcript variant 3 protein.
Length = 482
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 305 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 357
>AL603831-2|CAI40899.1| 562|Homo sapiens adenovirus 5 E1A binding
protein (BS69) protein.
Length = 562
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 385 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 437
>AL589988-2|CAH69846.1| 528|Homo sapiens adenovirus 5 E1A binding
protein (BS69) protein.
Length = 528
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 385 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 437
>AL589988-1|CAH69845.1| 562|Homo sapiens adenovirus 5 E1A binding
protein (BS69) protein.
Length = 562
Score = 31.5 bits (68), Expect = 6.6
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = -1
Query: 692 PGMPAEMNSASVSGHGRSLYCSHQRFTTRLT*KPSTNDIGIDSLCAPKYCRTFSN 528
P MP + SVS + L S R R T +TND S+C KY + F++
Sbjct: 385 PTMPQPIEKVSVSTQTKKLSASSPRMLHRST--QTTNDGVCQSMCHDKYTKIFND 437
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 159,121,742
Number of Sequences: 237096
Number of extensions: 3294031
Number of successful extensions: 11622
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11057
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11604
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17779932290
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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