Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_E11
(1176 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U67320-1|AAC51153.1| 303|Homo sapiens Lice2 gamma cysteine prot... 184 7e-46
U67319-1|AAC51152.1| 336|Homo sapiens Lice2 beta cysteine prote... 184 7e-46
U67206-1|AAF21460.1| 303|Homo sapiens Lice2 alpha protein. 184 7e-46
U40281-1|AAC50352.1| 303|Homo sapiens CMH-1 protein. 184 7e-46
U37448-1|AAC50303.1| 303|Homo sapiens Mch3 isoform alpha protein. 184 7e-46
BT006683-1|AAP35329.1| 303|Homo sapiens caspase 7, apoptosis-re... 184 7e-46
BC015799-1|AAH15799.1| 303|Homo sapiens caspase 7, apoptosis-re... 184 7e-46
AL627395-1|CAI16004.1| 303|Homo sapiens caspase 7, apoptosis-re... 184 7e-46
AL592546-3|CAI12638.1| 303|Homo sapiens caspase 7, apoptosis-re... 184 7e-46
U39613-1|AAC50346.1| 303|Homo sapiens ICE-LAP3 protein. 181 4e-45
BC004460-1|AAH04460.1| 293|Homo sapiens caspase 6, apoptosis-re... 171 6e-42
BC000305-1|AAH00305.1| 293|Homo sapiens caspase 6, apoptosis-re... 171 6e-42
AY254046-1|AAO63494.1| 293|Homo sapiens caspase 6, apoptosis-re... 171 6e-42
U20536-1|AAC50168.1| 293|Homo sapiens cysteine protease Mch2 is... 167 5e-41
U26943-1|AAA74929.1| 277|Homo sapiens Yama protein protein. 166 1e-40
U13738-1|AAB60355.1| 277|Homo sapiens cysteine protease CPP32 i... 166 1e-40
BC016926-1|AAH16926.1| 277|Homo sapiens caspase 3, apoptosis-re... 166 1e-40
AY219866-1|AAO25654.1| 277|Homo sapiens caspase 3, apoptosis-re... 166 1e-40
U13737-1|AAA65015.1| 277|Homo sapiens cysteine protease CPP32 i... 166 2e-40
AJ413269-1|CAC88866.1| 277|Homo sapiens caspase-3 protein. 166 2e-40
AF111345-1|AAD28403.1| 522|Homo sapiens caspase-10/d protein. 159 2e-38
EF050529-1|ABJ53426.1| 522|Homo sapiens caspase 10, apoptosis-r... 159 2e-38
BC042844-1|AAH42844.1| 522|Homo sapiens CASP10 protein protein. 159 2e-38
AC007283-1|AAY24291.1| 522|Homo sapiens unknown protein. 159 2e-38
U60519-1|AAC50644.1| 479|Homo sapiens apoptotic cysteine protea... 155 3e-37
AB038979-2|BAB32553.1| 479|Homo sapiens caspase-10a protein. 155 3e-37
U86214-1|AAB46730.1| 521|Homo sapiens Fas-associated death doma... 153 1e-36
AB038979-1|BAB32554.1| 521|Homo sapiens caspase-10b protein. 153 1e-36
AJ487679-1|CAD32372.1| 478|Homo sapiens caspase 10 protein. 149 1e-35
U60520-1|AAC50645.1| 496|Homo sapiens apoptotic cysteine protea... 143 1e-33
AF009620-1|AAB70913.1| 464|Homo sapiens apoptotic caspase Mch5-... 143 1e-33
AB038985-1|BAB32555.1| 496|Homo sapiens caspase-8 protein. 143 1e-33
X98173-1|CAA66854.1| 464|Homo sapiens MACH-alpha-2 protein. 140 1e-32
X98172-1|CAA66853.1| 479|Homo sapiens MACH-alpha-1 protein. 140 1e-32
U58143-1|AAC50602.1| 479|Homo sapiens FADD-homologous ICE/CED-3... 140 1e-32
DQ355026-1|ABC67468.1| 496|Homo sapiens caspase 8, apoptosis-re... 140 1e-32
AF422925-1|AAL87628.1| 538|Homo sapiens procaspase-8L protein. 140 1e-32
AC007256-3|AAY24225.1| 496|Homo sapiens unknown protein. 140 1e-32
AF102146-1|AAD24962.1| 479|Homo sapiens caspase 8 protein. 139 2e-32
AJ487678-1|CAD32371.1| 455|Homo sapiens caspase 10 protein. 126 2e-28
AL627395-3|CAI16006.1| 222|Homo sapiens caspase 7, apoptosis-re... 124 5e-28
AL592546-5|CAI12640.1| 222|Homo sapiens caspase 7, apoptosis-re... 124 5e-28
X98174-1|CAA66855.1| 266|Homo sapiens MACH-alpha-3 protein. 118 4e-26
U20537-1|AAC50169.1| 204|Homo sapiens cysteine protease Mch2 is... 117 9e-26
U13021-1|AAA58959.1| 435|Homo sapiens ICH-1L protein. 104 5e-22
BT007240-1|AAP35904.1| 435|Homo sapiens caspase 2, apoptosis-re... 104 5e-22
BC002427-1|AAH02427.2| 452|Homo sapiens caspase 2, apoptosis-re... 104 5e-22
AY219042-1|AAO25653.1| 435|Homo sapiens caspase 2, apoptosis-re... 104 5e-22
AC073342-1|AAP22346.1| 435|Homo sapiens unknown protein. 104 5e-22
BT006911-1|AAP35557.1| 416|Homo sapiens caspase 9, apoptosis-re... 103 2e-21
BC006463-1|AAH06463.1| 416|Homo sapiens caspase 9, apoptosis-re... 103 2e-21
BC002452-1|AAH02452.1| 416|Homo sapiens caspase 9, apoptosis-re... 103 2e-21
AL512883-7|CAC42423.1| 416|Homo sapiens caspase 9, apoptosis-re... 103 2e-21
U56390-1|AAC50640.1| 416|Homo sapiens ICE-LAP6 protein. 102 3e-21
AY214168-1|AAO21133.1| 416|Homo sapiens caspase 9, apoptosis-re... 102 3e-21
AB209147-1|BAD92384.1| 456|Homo sapiens caspase 9 isoform alpha... 101 7e-21
U60521-1|AAC50776.1| 416|Homo sapiens proMch6 protein. 100 1e-20
AB019205-1|BAA82697.1| 416|Homo sapiens Caspase-9 protein. 100 1e-20
BC103869-1|AAI03870.1| 242|Homo sapiens caspase 14, apoptosis-r... 92 3e-18
BC103868-1|AAI03869.1| 242|Homo sapiens caspase 14, apoptosis-r... 92 3e-18
BC069541-1|AAH69541.1| 242|Homo sapiens caspase 14, apoptosis-r... 92 3e-18
AF097874-1|AAD16173.1| 242|Homo sapiens caspase 14 precursor pr... 92 3e-18
AL512883-4|CAI12971.1| 197|Homo sapiens caspase 9, apoptosis-re... 77 2e-17
X65019-1|CAA46153.1| 404|Homo sapiens interleukin-1B converting... 89 4e-17
U13698-1|AAC50108.1| 311|Homo sapiens interleukin 1-beta conver... 89 4e-17
U13697-1|AAC50107.1| 383|Homo sapiens Interleukin 1-beta conver... 89 4e-17
M87507-1|AAA66942.1| 404|Homo sapiens interleukin 1-beta conver... 89 4e-17
BC062327-1|AAH62327.1| 311|Homo sapiens caspase 1, apoptosis-re... 89 4e-17
BC041689-1|AAH41689.1| 380|Homo sapiens CASP1 protein protein. 89 4e-17
AY660536-1|AAT72297.1| 365|Homo sapiens caspase-1 isoform zeta ... 89 4e-17
AK223503-1|BAD97223.1| 404|Homo sapiens caspase 1 isoform alpha... 89 4e-17
AL512883-5|CAI12972.1| 266|Homo sapiens caspase 9, apoptosis-re... 84 8e-16
U13022-1|AAA58960.1| 312|Homo sapiens ICH-1S protein. 82 4e-15
CR541748-1|CAG46548.1| 312|Homo sapiens CASP2 protein. 82 4e-15
AC073342-3|AAP22347.1| 312|Homo sapiens unknown protein. 82 4e-15
AF422927-1|AAL87630.1| 339|Homo sapiens procaspase-8 protein. 81 8e-15
AF422928-1|AAL87631.1| 353|Homo sapiens procaspase-8 protein. 78 5e-14
X94993-1|CAA64450.1| 364|Homo sapiens TY protease protein. 77 1e-13
BC074994-1|AAH74994.1| 418|Homo sapiens caspase 5, apoptosis-re... 77 1e-13
Z48810-1|CAA88750.1| 377|Homo sapiens TX protease precursor pro... 76 2e-13
U28979-2|AAC99854.1| 286|Homo sapiens Mih1/TX isoform delta pro... 76 2e-13
U28978-1|AAC99852.1| 321|Homo sapiens Mih1/TX isoform gamma pro... 76 2e-13
U28977-1|AAC99851.1| 331|Homo sapiens Mih1/TX isoform beta prot... 76 2e-13
U28976-1|AAC99850.1| 377|Homo sapiens Mih1/TX isoform alpha pro... 76 2e-13
U28014-1|AAA75171.1| 377|Homo sapiens cysteine protease protein. 76 2e-13
U25804-1|AAA86890.1| 377|Homo sapiens Ich-2 protein. 76 2e-13
EF636667-1|ABR09278.1| 377|Homo sapiens caspase 4, apoptosis-re... 76 2e-13
BC017839-1|AAH17839.1| 377|Homo sapiens caspase 4, apoptosis-re... 76 2e-13
U28015-1|AAA75172.1| 418|Homo sapiens cysteine protease protein. 76 3e-13
DQ508420-1|ABF47103.1| 418|Homo sapiens caspase 5, apoptosis-re... 76 3e-13
DQ228677-1|ABB58703.1| 447|Homo sapiens caspase-5/f protein. 76 3e-13
DQ228674-1|ABB58700.1| 292|Homo sapiens caspase-5/c protein. 76 3e-13
DQ228673-1|ABB58699.1| 376|Homo sapiens caspase-5/b protein. 76 3e-13
DQ228672-1|ABB58698.1| 434|Homo sapiens caspase-5/a protein. 76 3e-13
BC113406-1|AAI13407.1| 418|Homo sapiens caspase 5, apoptosis-re... 75 4e-13
U13699-1|AAC50109.1| 263|Homo sapiens Interleukin 1-beta conver... 69 4e-11
AY358222-1|AAQ88589.1| 341|Homo sapiens CASP12P1 protein. 68 6e-11
U37449-1|AAC50304.1| 253|Homo sapiens Mch3 isoform beta protein. 67 1e-10
AL627395-2|CAI16005.1| 253|Homo sapiens caspase 7, apoptosis-re... 67 1e-10
AL592546-4|CAI12639.1| 253|Homo sapiens caspase 7, apoptosis-re... 67 1e-10
AF078533-1|AAC28380.1| 377|Homo sapiens evolutionarily related ... 65 4e-10
AL050391-1|CAB43686.2| 104|Homo sapiens hypothetical protein pr... 52 4e-06
U97074-1|AAC51622.1| 480|Homo sapiens FLICE-like inhibitory pro... 50 2e-05
U85059-1|AAB82648.1| 480|Homo sapiens MRIT-alpha-1 protein. 50 2e-05
BT006751-1|AAP35397.1| 480|Homo sapiens CASP8 and FADD-like apo... 50 2e-05
BC001602-1|AAH01602.1| 480|Homo sapiens CASP8 and FADD-like apo... 50 2e-05
AF041461-1|AAB99793.1| 442|Homo sapiens I-FLICE isoform 4 protein. 50 2e-05
AF041460-1|AAB99792.1| 449|Homo sapiens I-FLICE isoform 3 protein. 50 2e-05
AF041459-1|AAB99791.1| 235|Homo sapiens I-FLICE isoform 2 protein. 50 2e-05
AF041458-1|AAB99790.1| 480|Homo sapiens I-FLICE protein. 50 2e-05
AF015451-1|AAC16440.1| 462|Homo sapiens Usurpin-beta protein. 50 2e-05
AF015450-1|AAC16439.1| 480|Homo sapiens Usurpin-alpha protein. 50 2e-05
AF010127-1|AAB64110.1| 480|Homo sapiens Casper protein. 50 2e-05
AF009618-1|AAB70911.1| 480|Homo sapiens FLAME-1-gamma protein. 50 2e-05
AF009616-1|AAB70909.1| 445|Homo sapiens FLAME-1 protein. 50 2e-05
AC007283-2|AAY24290.1| 480|Homo sapiens unknown protein. 50 2e-05
AB038972-1|BAB32552.1| 462|Homo sapiens usurpin beta protein. 50 2e-05
Y14039-1|CAA74366.1| 480|Homo sapiens CASH alpha protein protein. 49 3e-05
AF041462-1|AAB99794.1| 348|Homo sapiens I-FLICE isoform 5 protein. 49 3e-05
AF005774-1|AAC15825.1| 480|Homo sapiens caspase-like apoptosis ... 48 9e-05
AL512883-6|CAI12973.1| 266|Homo sapiens caspase 9, apoptosis-re... 47 2e-04
AF110376-1|AAD13615.1| 266|Homo sapiens caspase-9S precursor pr... 47 2e-04
AF093130-1|AAD12248.1| 266|Homo sapiens caspase 9 short isoform... 47 2e-04
AB020979-1|BAA87905.1| 266|Homo sapiens caspase-9 protein. 47 2e-04
AB015653-1|BAA78780.1| 266|Homo sapiens caspase-9 beta protein. 47 2e-04
AL627395-4|CAI16007.1| 220|Homo sapiens caspase 7, apoptosis-re... 44 8e-04
AL592546-6|CAI12641.1| 220|Homo sapiens caspase 7, apoptosis-re... 44 8e-04
AL512883-8|CAI12974.1| 254|Homo sapiens caspase 9, apoptosis-re... 36 0.28
AB209640-1|BAD92877.1| 144|Homo sapiens caspase 2 isoform 2 pre... 35 0.50
AL831992-1|CAD89916.1| 798|Homo sapiens hypothetical protein pr... 32 3.5
>U67320-1|AAC51153.1| 303|Homo sapiens Lice2 gamma cysteine protease
protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>U67319-1|AAC51152.1| 336|Homo sapiens Lice2 beta cysteine protease
protein.
Length = 336
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 91 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 150
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 151 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 210
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 211 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 270
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 271 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 322
>U67206-1|AAF21460.1| 303|Homo sapiens Lice2 alpha protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>U40281-1|AAC50352.1| 303|Homo sapiens CMH-1 protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>U37448-1|AAC50303.1| 303|Homo sapiens Mch3 isoform alpha protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>BT006683-1|AAP35329.1| 303|Homo sapiens caspase 7, apoptosis-related
cysteine protease protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>BC015799-1|AAH15799.1| 303|Homo sapiens caspase 7, apoptosis-related
cysteine peptidase protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>AL627395-1|CAI16004.1| 303|Homo sapiens caspase 7, apoptosis-related
cysteine peptidase protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>AL592546-3|CAI12638.1| 303|Homo sapiens caspase 7, apoptosis-related
cysteine peptidase protein.
Length = 303
Score = 184 bits (447), Expect = 7e-46
Identities = 97/235 (41%), Positives = 135/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>U39613-1|AAC50346.1| 303|Homo sapiens ICE-LAP3 protein.
Length = 303
Score = 181 bits (441), Expect = 4e-45
Identities = 96/235 (40%), Positives = 134/235 (57%), Gaps = 5/235 (2%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 864
PKLFFIQAC+G +LD I S D Y+IP+ ADFL +STVPGYYSWR+ R
Sbjct: 178 PKLFFIQACRGTELDDAIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGR 237
Query: 865 GSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXL---SQYPRYHXDASXKQVP 1020
GSWF+Q+LC L +G +I+ +LT V VA S P +H KQ+P
Sbjct: 238 GSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFH---EKKQIP 289
>BC004460-1|AAH04460.1| 293|Homo sapiens caspase 6, apoptosis-related
cysteine peptidase protein.
Length = 293
Score = 171 bits (415), Expect = 6e-42
Identities = 96/264 (36%), Positives = 135/264 (51%), Gaps = 12/264 (4%)
Frame = +1
Query: 265 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 441
A G ++ + K + A Y M+H RG+A+IFNHE F H L R GT D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRD 72
Query: 442 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 621
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 622 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGI-----------TLSNTETDG 768
+ L F DKC +L GKPK+F IQAC+G++ D + L T+
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEV 192
Query: 769 XXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFV 948
Y +P ADFL+ +S GYYS R T GSW++Q LCE L YG+ + LLT V
Sbjct: 193 DAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLV 252
Query: 949 CQXVALXLSQYPRYHXDASXKQVP 1020
+ V+ + + KQVP
Sbjct: 253 NRKVSQRRVDFCKDPSAIGKKQVP 276
>BC000305-1|AAH00305.1| 293|Homo sapiens caspase 6, apoptosis-related
cysteine peptidase protein.
Length = 293
Score = 171 bits (415), Expect = 6e-42
Identities = 96/264 (36%), Positives = 135/264 (51%), Gaps = 12/264 (4%)
Frame = +1
Query: 265 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 441
A G ++ + K + A Y M+H RG+A+IFNHE F H L R GT D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRD 72
Query: 442 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 621
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 622 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGI-----------TLSNTETDG 768
+ L F DKC +L GKPK+F IQAC+G++ D + L T+
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEV 192
Query: 769 XXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFV 948
Y +P ADFL+ +S GYYS R T GSW++Q LCE L YG+ + LLT V
Sbjct: 193 DAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLV 252
Query: 949 CQXVALXLSQYPRYHXDASXKQVP 1020
+ V+ + + KQVP
Sbjct: 253 NRKVSQRRVDFCKDPSAIGKKQVP 276
>AY254046-1|AAO63494.1| 293|Homo sapiens caspase 6, apoptosis-related
cysteine protease protein.
Length = 293
Score = 171 bits (415), Expect = 6e-42
Identities = 96/264 (36%), Positives = 135/264 (51%), Gaps = 12/264 (4%)
Frame = +1
Query: 265 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 441
A G ++ + K + A Y M+H RG+A+IFNHE F H L R GT D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRD 72
Query: 442 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 621
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 622 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGI-----------TLSNTETDG 768
+ L F DKC +L GKPK+F IQAC+G++ D + L T+
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEV 192
Query: 769 XXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFV 948
Y +P ADFL+ +S GYYS R T GSW++Q LCE L YG+ + LLT V
Sbjct: 193 DAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLV 252
Query: 949 CQXVALXLSQYPRYHXDASXKQVP 1020
+ V+ + + KQVP
Sbjct: 253 NRKVSQRRVDFCKDPSAIGKKQVP 276
>U20536-1|AAC50168.1| 293|Homo sapiens cysteine protease Mch2 isoform
alpha protein.
Length = 293
Score = 167 bits (407), Expect = 5e-41
Identities = 95/264 (35%), Positives = 134/264 (50%), Gaps = 12/264 (4%)
Frame = +1
Query: 265 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 441
A G ++ + K + A Y M+H RG+A+IFNHE F H L R T D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRRTCADRD 72
Query: 442 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 621
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 622 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGI-----------TLSNTETDG 768
+ L F DKC +L GKPK+F IQAC+G++ D + L T+
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEV 192
Query: 769 XXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFV 948
Y +P ADFL+ +S GYYS R T GSW++Q LCE L YG+ + LLT V
Sbjct: 193 DAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLV 252
Query: 949 CQXVALXLSQYPRYHXDASXKQVP 1020
+ V+ + + KQVP
Sbjct: 253 NRKVSQRRVDFCKDPSAIGKKQVP 276
>U26943-1|AAA74929.1| 277|Homo sapiens Yama protein protein.
Length = 277
Score = 166 bits (404), Expect = 1e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 1/229 (0%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 514 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 693
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 694 LFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSW 873
LF IQAC+G +LD GI + D ++IP+ ADFL +ST PGYYSWRN+ GSW
Sbjct: 157 LFIIQACRGTELDCGIETDSGVDD--DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSW 214
Query: 874 FMQSLCEELRNYGTQRDILTLLTFVCQXVALXLSQYPRYHXDASXKQVP 1020
F+QSLC L+ Y + + + +LT V + VA + + KQ+P
Sbjct: 215 FIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIP 263
>U13738-1|AAB60355.1| 277|Homo sapiens cysteine protease CPP32
isoform beta protein.
Length = 277
Score = 166 bits (404), Expect = 1e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 1/229 (0%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 514 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 693
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 694 LFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSW 873
LF IQAC+G +LD GI + D ++IP+ ADFL +ST PGYYSWRN+ GSW
Sbjct: 157 LFIIQACRGTELDCGIETDSGVDD--DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSW 214
Query: 874 FMQSLCEELRNYGTQRDILTLLTFVCQXVALXLSQYPRYHXDASXKQVP 1020
F+QSLC L+ Y + + + +LT V + VA + + KQ+P
Sbjct: 215 FIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIP 263
>BC016926-1|AAH16926.1| 277|Homo sapiens caspase 3, apoptosis-related
cysteine peptidase protein.
Length = 277
Score = 166 bits (404), Expect = 1e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 1/229 (0%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 514 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 693
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 694 LFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSW 873
LF IQAC+G +LD GI + D ++IP+ ADFL +ST PGYYSWRN+ GSW
Sbjct: 157 LFIIQACRGTELDCGIETDSGVDD--DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSW 214
Query: 874 FMQSLCEELRNYGTQRDILTLLTFVCQXVALXLSQYPRYHXDASXKQVP 1020
F+QSLC L+ Y + + + +LT V + VA + + KQ+P
Sbjct: 215 FIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIP 263
>AY219866-1|AAO25654.1| 277|Homo sapiens caspase 3, apoptosis-related
cysteine protease protein.
Length = 277
Score = 166 bits (404), Expect = 1e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 1/229 (0%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 514 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 693
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 694 LFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSW 873
LF IQAC+G +LD GI + D ++IP+ ADFL +ST PGYYSWRN+ GSW
Sbjct: 157 LFIIQACRGTELDCGIETDSGVDD--DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSW 214
Query: 874 FMQSLCEELRNYGTQRDILTLLTFVCQXVALXLSQYPRYHXDASXKQVP 1020
F+QSLC L+ Y + + + +LT V + VA + + KQ+P
Sbjct: 215 FIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIP 263
>U13737-1|AAA65015.1| 277|Homo sapiens cysteine protease CPP32
isoform alpha protein.
Length = 277
Score = 166 bits (403), Expect = 2e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 1/229 (0%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 514 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 693
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 694 LFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSW 873
LF IQAC+G +LD GI + D ++IP+ ADFL +ST PGYYSWRN+ GSW
Sbjct: 157 LFIIQACRGTELDCGIETDSGVDD--DMACHKIPVDADFLYAYSTAPGYYSWRNSKDGSW 214
Query: 874 FMQSLCEELRNYGTQRDILTLLTFVCQXVALXLSQYPRYHXDASXKQVP 1020
F+QSLC L+ Y + + + +LT V + VA + + KQ+P
Sbjct: 215 FIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIP 263
>AJ413269-1|CAC88866.1| 277|Homo sapiens caspase-3 protein.
Length = 277
Score = 166 bits (403), Expect = 2e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 1/229 (0%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 514 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 693
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 694 LFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSW 873
LF IQAC+G +LD GI + D ++IP+ ADFL +ST PGYYSWRN+ GSW
Sbjct: 157 LFIIQACRGTELDCGIETDSGVDD--DMACHKIPVDADFLYAYSTAPGYYSWRNSKDGSW 214
Query: 874 FMQSLCEELRNYGTQRDILTLLTFVCQXVALXLSQYPRYHXDASXKQVP 1020
F+QSLC L+ Y + + + +LT V + VA + + KQ+P
Sbjct: 215 FIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIP 263
>AF111345-1|AAD28403.1| 522|Homo sapiens caspase-10/d protein.
Length = 522
Score = 159 bits (386), Expect = 2e-38
Identities = 96/261 (36%), Positives = 142/261 (54%), Gaps = 7/261 (2%)
Frame = +1
Query: 202 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 381
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSEASTKRAA-VYRMNRNHRGLCVIVN 290
Query: 382 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 558
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 559 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 735
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 736 GITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
I++ N E IP ADFL+ +TVPGY S+R+ GSW++QSLC L+
Sbjct: 409 SISIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLK 467
Query: 904 N-YGTQRDILTLLTFVCQXVA 963
DIL++LT V V+
Sbjct: 468 KLVPRHEDILSILTAVNDDVS 488
>EF050529-1|ABJ53426.1| 522|Homo sapiens caspase 10,
apoptosis-related cysteine peptidase protein.
Length = 522
Score = 159 bits (385), Expect = 2e-38
Identities = 95/261 (36%), Positives = 142/261 (54%), Gaps = 7/261 (2%)
Frame = +1
Query: 202 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 381
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 382 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 558
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 559 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 735
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 736 GITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
+++ N E IP ADFL+ +TVPGY S+R+ GSW++QSLC L+
Sbjct: 409 SVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLK 467
Query: 904 N-YGTQRDILTLLTFVCQXVA 963
DIL++LT V V+
Sbjct: 468 KLVPRHEDILSILTAVNDDVS 488
>BC042844-1|AAH42844.1| 522|Homo sapiens CASP10 protein protein.
Length = 522
Score = 159 bits (385), Expect = 2e-38
Identities = 95/261 (36%), Positives = 142/261 (54%), Gaps = 7/261 (2%)
Frame = +1
Query: 202 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 381
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 382 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 558
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 559 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 735
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 736 GITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
+++ N E IP ADFL+ +TVPGY S+R+ GSW++QSLC L+
Sbjct: 409 SVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLK 467
Query: 904 N-YGTQRDILTLLTFVCQXVA 963
DIL++LT V V+
Sbjct: 468 KLVPRHEDILSILTAVNDDVS 488
>AC007283-1|AAY24291.1| 522|Homo sapiens unknown protein.
Length = 522
Score = 159 bits (385), Expect = 2e-38
Identities = 95/261 (36%), Positives = 142/261 (54%), Gaps = 7/261 (2%)
Frame = +1
Query: 202 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 381
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 382 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 558
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 559 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 735
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 736 GITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
+++ N E IP ADFL+ +TVPGY S+R+ GSW++QSLC L+
Sbjct: 409 SVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLK 467
Query: 904 N-YGTQRDILTLLTFVCQXVA 963
DIL++LT V V+
Sbjct: 468 KLVPRHEDILSILTAVNDDVS 488
>U60519-1|AAC50644.1| 479|Homo sapiens apoptotic cysteine protease
Mch4 protein.
Length = 479
Score = 155 bits (376), Expect = 3e-37
Identities = 86/219 (39%), Positives = 126/219 (57%), Gaps = 7/219 (3%)
Frame = +1
Query: 328 AHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
A Y MN N+RG+ +I N+ F +LK R GT+ D++ LS V + LGF+V + +N+
Sbjct: 230 AAVYRMNRNHRGLCVIVNNHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKV 287
Query: 508 DINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLA 681
++ +Q Q H D DC + +L+HG G +Y+ D P + +FTA +CP LA
Sbjct: 288 EMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLA 347
Query: 682 GKPKLFFIQACQGDKLDGGITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
KPKLFFIQACQG+++ +++ N E IP ADFL+ +TVPGY S+
Sbjct: 348 EKPKLFFIQACQGEEIQPSVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSF 406
Query: 850 RNTTRGSWFMQSLCEELRN-YGTQRDILTLLTFVCQXVA 963
R+ GSW++QSLC L+ DIL++LT V V+
Sbjct: 407 RHVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVNDDVS 445
>AB038979-2|BAB32553.1| 479|Homo sapiens caspase-10a protein.
Length = 479
Score = 155 bits (376), Expect = 3e-37
Identities = 86/219 (39%), Positives = 126/219 (57%), Gaps = 7/219 (3%)
Frame = +1
Query: 328 AHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
A Y MN N+RG+ +I N+ F +LK R GT+ D++ LS V + LGF+V + +N+
Sbjct: 230 AAVYRMNRNHRGLCVIVNNHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKV 287
Query: 508 DINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLA 681
++ +Q Q H D DC + +L+HG G +Y+ D P + +FTA +CP LA
Sbjct: 288 EMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLA 347
Query: 682 GKPKLFFIQACQGDKLDGGITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
KPKLFFIQACQG+++ +++ N E IP ADFL+ +TVPGY S+
Sbjct: 348 EKPKLFFIQACQGEEIQPSVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSF 406
Query: 850 RNTTRGSWFMQSLCEELRN-YGTQRDILTLLTFVCQXVA 963
R+ GSW++QSLC L+ DIL++LT V V+
Sbjct: 407 RHVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVNDDVS 445
>U86214-1|AAB46730.1| 521|Homo sapiens Fas-associated death domain
protein interleukin-1b-converting enzyme 2 protein.
Length = 521
Score = 153 bits (371), Expect = 1e-36
Identities = 88/240 (36%), Positives = 132/240 (55%), Gaps = 6/240 (2%)
Frame = +1
Query: 202 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 381
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 382 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 558
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 559 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 735
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 736 GITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
+++ N E IP ADFL+ +TVPGY S+R+ GSW++QSLC L+
Sbjct: 409 SVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLK 467
>AB038979-1|BAB32554.1| 521|Homo sapiens caspase-10b protein.
Length = 521
Score = 153 bits (371), Expect = 1e-36
Identities = 88/240 (36%), Positives = 132/240 (55%), Gaps = 6/240 (2%)
Frame = +1
Query: 202 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 381
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 382 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 558
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 559 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 735
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 736 GITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
+++ N E IP ADFL+ +TVPGY S+R+ GSW++QSLC L+
Sbjct: 409 SVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLK 467
>AJ487679-1|CAD32372.1| 478|Homo sapiens caspase 10 protein.
Length = 478
Score = 149 bits (362), Expect = 1e-35
Identities = 79/198 (39%), Positives = 116/198 (58%), Gaps = 6/198 (3%)
Frame = +1
Query: 328 AHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
A Y MN N+RG+ +I N+ F +LK R GT+ D++ LS V + LGF+V + +N+
Sbjct: 230 AAVYRMNRNHRGLCVIVNNHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKV 287
Query: 508 DINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLA 681
++ +Q Q H D DC + +L+HG G +Y+ D P + +FTA +CP LA
Sbjct: 288 EMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLA 347
Query: 682 GKPKLFFIQACQGDKLDGGITLS----NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
KPKLFFIQACQG+++ +++ N E IP ADFL+ +TVPGY S+
Sbjct: 348 EKPKLFFIQACQGEEIQPSVSIEADALNPE-QAPTSLQDSIPAEADFLLGLATVPGYVSF 406
Query: 850 RNTTRGSWFMQSLCEELR 903
R+ GSW++QSLC L+
Sbjct: 407 RHVEEGSWYIQSLCNHLK 424
>U60520-1|AAC50645.1| 496|Homo sapiens apoptotic cysteine protease
Mch5 isoform alpha protein.
Length = 496
Score = 143 bits (347), Expect = 1e-33
Identities = 82/221 (37%), Positives = 118/221 (53%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F + H
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHH 302
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 422
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 423 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 463
>AF009620-1|AAB70913.1| 464|Homo sapiens apoptotic caspase
Mch5-beta protein.
Length = 464
Score = 143 bits (347), Expect = 1e-33
Identities = 82/221 (37%), Positives = 118/221 (53%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F + H
Sbjct: 211 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHH 270
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 271 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 330
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 331 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 390
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 391 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 431
>AB038985-1|BAB32555.1| 496|Homo sapiens caspase-8 protein.
Length = 496
Score = 143 bits (347), Expect = 1e-33
Identities = 82/221 (37%), Positives = 118/221 (53%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F + H
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHH 302
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 422
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 423 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 463
>X98173-1|CAA66854.1| 464|Homo sapiens MACH-alpha-2 protein.
Length = 464
Score = 140 bits (338), Expect = 1e-32
Identities = 81/221 (36%), Positives = 117/221 (52%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 211 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 270
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 271 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 330
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 331 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 390
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 391 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 431
>X98172-1|CAA66853.1| 479|Homo sapiens MACH-alpha-1 protein.
Length = 479
Score = 140 bits (338), Expect = 1e-32
Identities = 81/221 (36%), Positives = 117/221 (52%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 286 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 345
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 346 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 405
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 406 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 446
>U58143-1|AAC50602.1| 479|Homo sapiens FADD-homologous
ICE/CED-3-like protease protein.
Length = 479
Score = 140 bits (338), Expect = 1e-32
Identities = 81/221 (36%), Positives = 117/221 (52%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 286 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEPPIYELTSQFTGLKC 345
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 346 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 405
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 406 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 446
>DQ355026-1|ABC67468.1| 496|Homo sapiens caspase 8,
apoptosis-related cysteine peptidase protein.
Length = 496
Score = 140 bits (338), Expect = 1e-32
Identities = 81/221 (36%), Positives = 117/221 (52%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 302
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 422
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 423 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 463
>AF422925-1|AAL87628.1| 538|Homo sapiens procaspase-8L protein.
Length = 538
Score = 140 bits (338), Expect = 1e-32
Identities = 81/221 (36%), Positives = 117/221 (52%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 285 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 344
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 345 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 404
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 405 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 464
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 465 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 505
>AC007256-3|AAY24225.1| 496|Homo sapiens unknown protein.
Length = 496
Score = 140 bits (338), Expect = 1e-32
Identities = 81/221 (36%), Positives = 117/221 (52%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 302
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 422
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 423 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 463
>AF102146-1|AAD24962.1| 479|Homo sapiens caspase 8 protein.
Length = 479
Score = 139 bits (336), Expect = 2e-32
Identities = 81/221 (36%), Positives = 117/221 (52%), Gaps = 17/221 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 286 DCTVEQIYDILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEPPIYELTSQFTGLKC 345
Query: 670 PTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADFLIVFST 828
P+LAGKPK+FFIQACQGD GI + E D IP ADFL+ +T
Sbjct: 346 PSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMAT 405
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
V S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 406 VNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 446
>AJ487678-1|CAD32371.1| 455|Homo sapiens caspase 10 protein.
Length = 455
Score = 126 bits (303), Expect = 2e-28
Identities = 70/183 (38%), Positives = 104/183 (56%), Gaps = 7/183 (3%)
Frame = +1
Query: 436 SDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYA 612
++ LS V + LGF+V + +N+ ++ +Q Q H D DC + +L+HG G +Y+
Sbjct: 240 NEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYS 299
Query: 613 KDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS----NTETDGXXX 777
D P + +FTA +CP LA KPKLFFIQACQG+++ +++ N E
Sbjct: 300 SDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE-QAPTS 358
Query: 778 XXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN-YGTQRDILTLLTFVCQ 954
IP ADFL+ +TVPGY S+R+ GSW++QSLC L+ DIL++LT V
Sbjct: 359 LQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVND 418
Query: 955 XVA 963
V+
Sbjct: 419 DVS 421
>AL627395-3|CAI16006.1| 222|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 222
Score = 124 bits (300), Expect = 5e-28
Identities = 65/163 (39%), Positives = 93/163 (57%), Gaps = 2/163 (1%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFL 813
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFL 220
>AL592546-5|CAI12640.1| 222|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 222
Score = 124 bits (300), Expect = 5e-28
Identities = 65/163 (39%), Positives = 93/163 (57%), Gaps = 2/163 (1%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 687
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 688 PKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFL 813
PKLFFIQAC+G +LD GI S D Y+IP+ ADFL
Sbjct: 178 PKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFL 220
>X98174-1|CAA66855.1| 266|Homo sapiens MACH-alpha-3 protein.
Length = 266
Score = 118 bits (284), Expect = 4e-26
Identities = 69/178 (38%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Frame = +1
Query: 442 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 621
+L+ L F + + E I ++ MDH++ DC + +LSHG+ G++Y D
Sbjct: 56 ALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDG 115
Query: 622 HYKPD-NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXX 777
P L FT KCP+LAGKPK+FFIQACQGD GI + E D
Sbjct: 116 QEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSP 175
Query: 778 XXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQ-RDILTLLTFV 948
IP ADFL+ +TV S+RN G+W++QSLC+ LR + DILT+LT V
Sbjct: 176 QTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEV 233
>U20537-1|AAC50169.1| 204|Homo sapiens cysteine protease Mch2 isoform
beta protein.
Length = 204
Score = 117 bits (281), Expect = 9e-26
Identities = 66/184 (35%), Positives = 90/184 (48%), Gaps = 11/184 (5%)
Frame = +1
Query: 502 AEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLA 681
A + R +S + H D DC + LSHGE +YA D + L F DKC +L
Sbjct: 4 ASGLRRGHPAVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLV 63
Query: 682 GKPKLFFIQACQGDKLDGGI-----------TLSNTETDGXXXXXYRIPIHADFLIVFST 828
GKPK+F IQAC+G++ D + L T+ Y +P ADFL+ +S
Sbjct: 64 GKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSV 123
Query: 829 VPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVALXLSQYPRYHXDASX 1008
GYYS R T GSW++Q LCE L YG+ + LLT V + V+ + +
Sbjct: 124 AEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGK 183
Query: 1009 KQVP 1020
KQVP
Sbjct: 184 KQVP 187
>U13021-1|AAA58959.1| 435|Homo sapiens ICH-1L protein.
Length = 435
Score = 104 bits (250), Expect = 5e-22
Identities = 61/201 (30%), Positives = 107/201 (53%), Gaps = 15/201 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 688 PKLFFIQACQGDKLDGGITLSN----------TETDGXXXXX--YRIPIHADFLIVFSTV 831
PK+FFIQAC+GD+ D G+ + E+D R+P +D + ++ +
Sbjct: 295 PKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACL 354
Query: 832 PGYYSWRNTTRGSWFMQSLCE 894
G + RNT RGSW++++L +
Sbjct: 355 KGTAAMRNTKRGSWYIEALAQ 375
>BT007240-1|AAP35904.1| 435|Homo sapiens caspase 2,
apoptosis-related cysteine protease (neural precursor
cell expressed protein.
Length = 435
Score = 104 bits (250), Expect = 5e-22
Identities = 61/201 (30%), Positives = 107/201 (53%), Gaps = 15/201 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 688 PKLFFIQACQGDKLDGGITLSN----------TETDGXXXXX--YRIPIHADFLIVFSTV 831
PK+FFIQAC+GD+ D G+ + E+D R+P +D + ++ +
Sbjct: 295 PKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACL 354
Query: 832 PGYYSWRNTTRGSWFMQSLCE 894
G + RNT RGSW++++L +
Sbjct: 355 KGTAAMRNTKRGSWYIEALAQ 375
>BC002427-1|AAH02427.2| 452|Homo sapiens caspase 2,
apoptosis-related cysteine peptidase (neural precursor
cell expresse protein.
Length = 452
Score = 104 bits (250), Expect = 5e-22
Identities = 61/201 (30%), Positives = 107/201 (53%), Gaps = 15/201 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 192 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 251
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 252 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 311
Query: 688 PKLFFIQACQGDKLDGGITLSN----------TETDGXXXXX--YRIPIHADFLIVFSTV 831
PK+FFIQAC+GD+ D G+ + E+D R+P +D + ++ +
Sbjct: 312 PKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACL 371
Query: 832 PGYYSWRNTTRGSWFMQSLCE 894
G + RNT RGSW++++L +
Sbjct: 372 KGTAAMRNTKRGSWYIEALAQ 392
>AY219042-1|AAO25653.1| 435|Homo sapiens caspase 2,
apoptosis-related cysteine protease (neural precursor
cell expressed protein.
Length = 435
Score = 104 bits (250), Expect = 5e-22
Identities = 61/201 (30%), Positives = 107/201 (53%), Gaps = 15/201 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 688 PKLFFIQACQGDKLDGGITLSN----------TETDGXXXXX--YRIPIHADFLIVFSTV 831
PK+FFIQAC+GD+ D G+ + E+D R+P +D + ++ +
Sbjct: 295 PKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACL 354
Query: 832 PGYYSWRNTTRGSWFMQSLCE 894
G + RNT RGSW++++L +
Sbjct: 355 KGTAAMRNTKRGSWYIEALAQ 375
>AC073342-1|AAP22346.1| 435|Homo sapiens unknown protein.
Length = 435
Score = 104 bits (250), Expect = 5e-22
Identities = 61/201 (30%), Positives = 107/201 (53%), Gaps = 15/201 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 688 PKLFFIQACQGDKLDGGITLSN----------TETDGXXXXX--YRIPIHADFLIVFSTV 831
PK+FFIQAC+GD+ D G+ + E+D R+P +D + ++ +
Sbjct: 295 PKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACL 354
Query: 832 PGYYSWRNTTRGSWFMQSLCE 894
G + RNT RGSW++++L +
Sbjct: 355 KGTAAMRNTKRGSWYIEALAQ 375
>BT006911-1|AAP35557.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine protease protein.
Length = 416
Score = 103 bits (246), Expect = 2e-21
Identities = 70/233 (30%), Positives = 112/233 (48%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>BC006463-1|AAH06463.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 416
Score = 103 bits (246), Expect = 2e-21
Identities = 70/233 (30%), Positives = 112/233 (48%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>BC002452-1|AAH02452.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 416
Score = 103 bits (246), Expect = 2e-21
Identities = 70/233 (30%), Positives = 112/233 (48%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>AL512883-7|CAC42423.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 416
Score = 103 bits (246), Expect = 2e-21
Identities = 70/233 (30%), Positives = 112/233 (48%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>U56390-1|AAC50640.1| 416|Homo sapiens ICE-LAP6 protein.
Length = 416
Score = 102 bits (244), Expect = 3e-21
Identities = 70/233 (30%), Positives = 111/233 (47%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 RQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>AY214168-1|AAO21133.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine protease protein.
Length = 416
Score = 102 bits (244), Expect = 3e-21
Identities = 70/233 (30%), Positives = 111/233 (47%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 RQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>AB209147-1|BAD92384.1| 456|Homo sapiens caspase 9 isoform alpha
preproprotein variant protein.
Length = 456
Score = 101 bits (241), Expect = 7e-21
Identities = 68/224 (30%), Positives = 108/224 (48%), Gaps = 31/224 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 196 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 255
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 256 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 315
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 316 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 375
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLL 939
+ +ST PG+ SWR+ GSW++++L + + D+ +LL
Sbjct: 376 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLL 419
>U60521-1|AAC50776.1| 416|Homo sapiens proMch6 protein.
Length = 416
Score = 100 bits (239), Expect = 1e-20
Identities = 69/233 (29%), Positives = 111/233 (47%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSPHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>AB019205-1|BAA82697.1| 416|Homo sapiens Caspase-9 protein.
Length = 416
Score = 100 bits (239), Expect = 1e-20
Identities = 69/233 (29%), Positives = 111/233 (47%), Gaps = 31/233 (13%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSPHFMVEVKGDLTAKKMVLALLELA 220
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 694 LFFIQACQGDKLDGGITL-----------SNTETDG-----------XXXXXYRIPIHAD 807
LFFIQAC G++ D G + SN E D +P +D
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD 340
Query: 808 FLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+ +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 341 IFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 393
>BC103869-1|AAI03870.1| 242|Homo sapiens caspase 14,
apoptosis-related cysteine peptidase protein.
Length = 242
Score = 92.3 bits (219), Expect = 3e-18
Identities = 60/190 (31%), Positives = 95/190 (50%), Gaps = 5/190 (2%)
Frame = +1
Query: 409 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 579
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 580 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNT 756
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 757 E-TDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILT 933
E IP + D L V+STV GY ++R+ +GS F+Q+L + + IL
Sbjct: 147 EIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTK--RKGHILE 204
Query: 934 LLTFVCQXVA 963
LLT V + +A
Sbjct: 205 LLTEVTRRMA 214
>BC103868-1|AAI03869.1| 242|Homo sapiens caspase 14,
apoptosis-related cysteine peptidase protein.
Length = 242
Score = 92.3 bits (219), Expect = 3e-18
Identities = 60/190 (31%), Positives = 95/190 (50%), Gaps = 5/190 (2%)
Frame = +1
Query: 409 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 579
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 580 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNT 756
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 757 E-TDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILT 933
E IP + D L V+STV GY ++R+ +GS F+Q+L + + IL
Sbjct: 147 EIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTK--RKGHILE 204
Query: 934 LLTFVCQXVA 963
LLT V + +A
Sbjct: 205 LLTEVTRRMA 214
>BC069541-1|AAH69541.1| 242|Homo sapiens caspase 14,
apoptosis-related cysteine peptidase protein.
Length = 242
Score = 92.3 bits (219), Expect = 3e-18
Identities = 60/190 (31%), Positives = 95/190 (50%), Gaps = 5/190 (2%)
Frame = +1
Query: 409 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 579
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 580 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNT 756
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 757 E-TDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILT 933
E IP + D L V+STV GY ++R+ +GS F+Q+L + + IL
Sbjct: 147 EIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTK--RKGHILE 204
Query: 934 LLTFVCQXVA 963
LLT V + +A
Sbjct: 205 LLTEVTRRMA 214
>AF097874-1|AAD16173.1| 242|Homo sapiens caspase 14 precursor
protein.
Length = 242
Score = 92.3 bits (219), Expect = 3e-18
Identities = 60/190 (31%), Positives = 95/190 (50%), Gaps = 5/190 (2%)
Frame = +1
Query: 409 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 579
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 580 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNT 756
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 757 E-TDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILT 933
E IP + D L V+STV GY ++R+ +GS F+Q+L + + IL
Sbjct: 147 EIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTK--RKGHILE 204
Query: 934 LLTFVCQXVA 963
LLT V + +A
Sbjct: 205 LLTEVTRRMA 214
>AL512883-4|CAI12971.1| 197|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 197
Score = 76.6 bits (180), Expect(2) = 2e-17
Identities = 46/129 (35%), Positives = 69/129 (53%), Gaps = 9/129 (6%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 2 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 61
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 62 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 121
Query: 694 LFFIQACQG 720
LFFIQAC G
Sbjct: 122 LFFIQACGG 130
Score = 33.9 bits (74), Expect(2) = 2e-17
Identities = 13/44 (29%), Positives = 25/44 (56%)
Frame = +1
Query: 835 GYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
G+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 131 GFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 174
>X65019-1|CAA46153.1| 404|Homo sapiens interleukin-1B converting
enzyme protein.
Length = 404
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 164 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 281
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 282 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFIAFCSSTPDNVSW 340
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 341 RHPTMGSVFIGRLIEHMQEYACSCDV 366
>U13698-1|AAC50108.1| 311|Homo sapiens interleukin 1-beta
converting enzyme isoform gamma protein.
Length = 311
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 71 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 128
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 129 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 188
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 189 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFIAFCSSTPDNVSW 247
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 248 RHPTMGSVFIGRLIEHMQEYACSCDV 273
>U13697-1|AAC50107.1| 383|Homo sapiens Interleukin 1-beta
converting enzyme isoform beta protein.
Length = 383
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 143 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 200
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 201 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 260
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 261 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFIAFCSSTPDNVSW 319
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 320 RHPTMGSVFIGRLIEHMQEYACSCDV 345
>M87507-1|AAA66942.1| 404|Homo sapiens interleukin 1-beta
convertase protein.
Length = 404
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 164 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 281
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 282 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFIAFCSSTPDNVSW 340
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 341 RHPTMGSVFIGRLIEHMQEYACSCDV 366
>BC062327-1|AAH62327.1| 311|Homo sapiens caspase 1,
apoptosis-related cysteine peptidase (interleukin 1,
beta, convertas protein.
Length = 311
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 71 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 128
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 129 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 188
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 189 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFIAFCSSTPDNVSW 247
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 248 RHPTMGSVFIGRLIEHMQEYACSCDV 273
>BC041689-1|AAH41689.1| 380|Homo sapiens CASP1 protein protein.
Length = 380
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 140 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 197
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 198 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 257
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 258 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFIAFCSSTPDNVSW 316
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 317 RHPTMGSVFIGRLIEHMQEYACSCDV 342
>AY660536-1|AAT72297.1| 365|Homo sapiens caspase-1 isoform zeta
precursor protein.
Length = 365
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 125 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 182
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 183 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 242
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 243 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFIAFCSSTPDNVSW 301
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 302 RHPTMGSVFIGRLIEHMQEYACSCDV 327
>AK223503-1|BAD97223.1| 404|Homo sapiens caspase 1 isoform alpha
precursor variant protein.
Length = 404
Score = 88.6 bits (210), Expect = 4e-17
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 18/206 (8%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 164 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 281
Query: 703 IQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 849
IQAC+GD + G ++L TE + + I DF+ S+ P SW
Sbjct: 282 IQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIRKAHIEKDFIAFCSSTPDNVSW 340
Query: 850 RNTTRGSWFMQSLCEELRNYGTQRDI 927
R+ T GS F+ L E ++ Y D+
Sbjct: 341 RHPTMGSVFIGRLIEHMQEYACSCDV 366
>AL512883-5|CAI12972.1| 266|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 266
Score = 84.2 bits (199), Expect = 8e-16
Identities = 49/144 (34%), Positives = 78/144 (54%), Gaps = 9/144 (6%)
Frame = +1
Query: 361 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 537
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 78 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 137
Query: 538 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 693
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 138 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 197
Query: 694 LFFIQACQGDKLDGGITLSNTETD 765
LFFIQAC G++ D G +++T +
Sbjct: 198 LFFIQACGGEQKDHGFEVASTSPE 221
>U13022-1|AAA58960.1| 312|Homo sapiens ICH-1S protein.
Length = 312
Score = 81.8 bits (193), Expect = 4e-15
Identities = 44/131 (33%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 161 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 220
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 221 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 280
Query: 688 PKLFFIQACQG 720
PK+FFIQAC+G
Sbjct: 281 PKMFFIQACRG 291
>CR541748-1|CAG46548.1| 312|Homo sapiens CASP2 protein.
Length = 312
Score = 81.8 bits (193), Expect = 4e-15
Identities = 44/131 (33%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 161 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 220
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 221 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 280
Query: 688 PKLFFIQACQG 720
PK+FFIQAC+G
Sbjct: 281 PKMFFIQACRG 291
>AC073342-3|AAP22347.1| 312|Homo sapiens unknown protein.
Length = 312
Score = 81.8 bits (193), Expect = 4e-15
Identities = 44/131 (33%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 513
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 161 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 220
Query: 514 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 687
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 221 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 280
Query: 688 PKLFFIQACQG 720
PK+FFIQAC+G
Sbjct: 281 PKMFFIQACRG 291
>AF422927-1|AAL87630.1| 339|Homo sapiens procaspase-8 protein.
Length = 339
Score = 81.0 bits (191), Expect = 8e-15
Identities = 42/129 (32%), Positives = 68/129 (52%), Gaps = 9/129 (6%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 211 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 270
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 271 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 330
Query: 670 PTLAGKPKL 696
P+LAGKPK+
Sbjct: 331 PSLAGKPKV 339
>AF422928-1|AAL87631.1| 353|Homo sapiens procaspase-8 protein.
Length = 353
Score = 78.2 bits (184), Expect = 5e-14
Identities = 41/128 (32%), Positives = 66/128 (51%), Gaps = 9/128 (7%)
Frame = +1
Query: 337 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 492
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 669
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT C
Sbjct: 286 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGFGC 345
Query: 670 PTLAGKPK 693
P+LAGKPK
Sbjct: 346 PSLAGKPK 353
>X94993-1|CAA64450.1| 364|Homo sapiens TY protease protein.
Length = 364
Score = 77.0 bits (181), Expect = 1e-13
Identities = 57/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 120 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 177
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 178 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 237
Query: 691 KLFFIQACQGDK--------LDGGITLSNTETDGXXXXXYRIPIH--ADFLIVFSTVPGY 840
K+ +QAC+G+K + L ++++ IH DF+ S+ P
Sbjct: 238 KVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 297
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 298 VSWRDRTRGSIFITELITCFQKY 320
>BC074994-1|AAH74994.1| 418|Homo sapiens caspase 5,
apoptosis-related cysteine peptidase protein.
Length = 418
Score = 77.0 bits (181), Expect = 1e-13
Identities = 57/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 691 KLFFIQACQGDK--------LDGGITLSNTETDGXXXXXYRIPIH--ADFLIVFSTVPGY 840
K+ +QAC+G+K + L ++++ IH DF+ S+ P
Sbjct: 292 KVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 351
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 352 VSWRDRTRGSIFITELITCFQKY 374
>Z48810-1|CAA88750.1| 377|Homo sapiens TX protease precursor
protein.
Length = 377
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 272
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 273 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 332
Query: 907 Y 909
Y
Sbjct: 333 Y 333
>U28979-2|AAC99854.1| 286|Homo sapiens Mih1/TX isoform delta
protein.
Length = 286
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 4 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 61
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 62 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 121
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 122 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 181
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 182 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 241
Query: 907 Y 909
Y
Sbjct: 242 Y 242
>U28978-1|AAC99852.1| 321|Homo sapiens Mih1/TX isoform gamma
protein.
Length = 321
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 39 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 96
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 97 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 156
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 157 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 216
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 217 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 276
Query: 907 Y 909
Y
Sbjct: 277 Y 277
>U28977-1|AAC99851.1| 331|Homo sapiens Mih1/TX isoform beta
protein.
Length = 331
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 49 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 106
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 107 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 166
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 167 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 226
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 227 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 286
Query: 907 Y 909
Y
Sbjct: 287 Y 287
>U28976-1|AAC99850.1| 377|Homo sapiens Mih1/TX isoform alpha
protein.
Length = 377
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 272
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 273 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 332
Query: 907 Y 909
Y
Sbjct: 333 Y 333
>U28014-1|AAA75171.1| 377|Homo sapiens cysteine protease protein.
Length = 377
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 272
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 273 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 332
Query: 907 Y 909
Y
Sbjct: 333 Y 333
>U25804-1|AAA86890.1| 377|Homo sapiens Ich-2 protein.
Length = 377
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 272
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 273 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 332
Query: 907 Y 909
Y
Sbjct: 333 Y 333
>EF636667-1|ABR09278.1| 377|Homo sapiens caspase 4,
apoptosis-related cysteine peptidase protein.
Length = 377
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 272
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 273 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 332
Query: 907 Y 909
Y
Sbjct: 333 Y 333
>BC017839-1|AAH17839.1| 377|Homo sapiens caspase 4,
apoptosis-related cysteine peptidase protein.
Length = 377
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/241 (26%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Frame = +1
Query: 244 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 417
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 418 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 594
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 595 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQGDKL------DGG 738
L G+ KPD L Y F C +L KPK+ +QAC+G D
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP 272
Query: 739 ITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRN 906
+L S + + Y+ + DF+ S+ P SWR++T GS F+ L +
Sbjct: 273 ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQK 332
Query: 907 Y 909
Y
Sbjct: 333 Y 333
>U28015-1|AAA75172.1| 418|Homo sapiens cysteine protease protein.
Length = 418
Score = 75.8 bits (178), Expect = 3e-13
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 691 KLFFIQACQGDK------LDGGITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGY 840
K+ +QAC+G+K D +L S + + +I DF+ S+ P
Sbjct: 292 KVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 351
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 352 VSWRDRTRGSIFITELITCFQKY 374
>DQ508420-1|ABF47103.1| 418|Homo sapiens caspase 5,
apoptosis-related cysteine peptidase protein.
Length = 418
Score = 75.8 bits (178), Expect = 3e-13
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 691 KLFFIQACQGDK------LDGGITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGY 840
K+ +QAC+G+K D +L S + + +I DF+ S+ P
Sbjct: 292 KVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 351
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 352 VSWRDRTRGSIFITELITCFQKY 374
>DQ228677-1|ABB58703.1| 447|Homo sapiens caspase-5/f protein.
Length = 447
Score = 75.8 bits (178), Expect = 3e-13
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 203 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 260
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 261 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 320
Query: 691 KLFFIQACQGDK------LDGGITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGY 840
K+ +QAC+G+K D +L S + + +I DF+ S+ P
Sbjct: 321 KVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 380
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 381 VSWRDRTRGSIFITELITCFQKY 403
>DQ228674-1|ABB58700.1| 292|Homo sapiens caspase-5/c protein.
Length = 292
Score = 75.8 bits (178), Expect = 3e-13
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 48 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 105
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 106 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 165
Query: 691 KLFFIQACQGDK------LDGGITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGY 840
K+ +QAC+G+K D +L S + + +I DF+ S+ P
Sbjct: 166 KVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 225
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 226 VSWRDRTRGSIFITELITCFQKY 248
>DQ228673-1|ABB58699.1| 376|Homo sapiens caspase-5/b protein.
Length = 376
Score = 75.8 bits (178), Expect = 3e-13
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 132 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 189
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 190 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 249
Query: 691 KLFFIQACQGDK------LDGGITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGY 840
K+ +QAC+G+K D +L S + + +I DF+ S+ P
Sbjct: 250 KVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 309
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 310 VSWRDRTRGSIFITELITCFQKY 332
>DQ228672-1|ABB58698.1| 434|Homo sapiens caspase-5/a protein.
Length = 434
Score = 75.8 bits (178), Expect = 3e-13
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 190 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 247
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 248 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 307
Query: 691 KLFFIQACQGDK------LDGGITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGY 840
K+ +QAC+G+K D +L S + + +I DF+ S+ P
Sbjct: 308 KVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 367
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 368 VSWRDRTRGSIFITELITCFQKY 390
>BC113406-1|AAI13407.1| 418|Homo sapiens caspase 5,
apoptosis-related cysteine peptidase protein.
Length = 418
Score = 75.4 bits (177), Expect = 4e-13
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 17/203 (8%)
Frame = +1
Query: 352 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 531
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDILGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 532 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 690
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 691 KLFFIQACQGDK------LDGGITL----SNTETDGXXXXXYRIPIHADFLIVFSTVPGY 840
K+ +QAC+G+K D +L S + + +I DF+ S+ P
Sbjct: 292 KVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHN 351
Query: 841 YSWRNTTRGSWFMQSLCEELRNY 909
SWR+ TRGS F+ L + Y
Sbjct: 352 VSWRDRTRGSIFITELITCFQKY 374
>U13699-1|AAC50109.1| 263|Homo sapiens Interleukin 1-beta
converting enzyme isoform delta protein.
Length = 263
Score = 68.5 bits (160), Expect = 4e-11
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 7/129 (5%)
Frame = +1
Query: 364 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 543
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 71 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 128
Query: 544 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 702
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 129 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 188
Query: 703 IQACQGDKL 729
IQAC+GD +
Sbjct: 189 IQACRGDNV 197
>AY358222-1|AAQ88589.1| 341|Homo sapiens CASP12P1 protein.
Length = 341
Score = 68.1 bits (159), Expect = 6e-11
Identities = 50/196 (25%), Positives = 89/196 (45%), Gaps = 19/196 (9%)
Frame = +1
Query: 379 NHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS-EMDHTD 555
N + E + L +R G+ +D + +L LG+SV + NL A+++ ++Q + +H
Sbjct: 102 NIRNKEFNYLHNRNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQS 161
Query: 556 NDCLLVAVLSHGEL-GMLYAKDTHYKPD-----NLWYYFTADKCPTLAGKPKLFFIQACQ 717
+D + +SH L G+ K +PD ++ F C +L KPK+ +QAC+
Sbjct: 162 SDSTFLVFMSHSILNGICGTKHWDQEPDVLHDDTIFEIFNNRNCQSLKDKPKVIIMQACR 221
Query: 718 GD-------KLDGGITLSNT-----ETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTT 861
G+ D G ++T + + + + DF+ S+ P SWR+ T
Sbjct: 222 GNGAGIVWFTTDSGKASADTHGRLLQGNICNDAVTKAHVEKDFIAFKSSTPHNVSWRHET 281
Query: 862 RGSWFMQSLCEELRNY 909
GS F+ + R Y
Sbjct: 282 NGSVFISQIIYYFREY 297
>U37449-1|AAC50304.1| 253|Homo sapiens Mch3 isoform beta protein.
Length = 253
Score = 66.9 bits (156), Expect = 1e-10
Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGM 603
+ +++ SE DHT+ C +LSHGE M
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENM 149
>AL627395-2|CAI16005.1| 253|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 253
Score = 66.9 bits (156), Expect = 1e-10
Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGM 603
+ +++ SE DHT+ C +LSHGE M
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENM 149
>AL592546-4|CAI12639.1| 253|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 253
Score = 66.9 bits (156), Expect = 1e-10
Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 507
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 508 DINRYIQQISEMDHTDNDCLLVAVLSHGELGM 603
+ +++ SE DHT+ C +LSHGE M
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENM 149
>AF078533-1|AAC28380.1| 377|Homo sapiens evolutionarily related
interleukin-1beta converting enzyme protein.
Length = 377
Score = 65.3 bits (152), Expect = 4e-10
Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 19/222 (8%)
Frame = +1
Query: 301 YAKMPVERYAHYYNMNH--NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGF 474
+ K+ ER Y + + +A+I + F+ ++ R G +D + ++L GLG+
Sbjct: 114 FLKLCKERAGEIYPIKERKDRTRLALIICNTEFD--HMPPRNGAALDILGMKQLLEGLGY 171
Query: 475 SVTVLHNLRAEDINRYIQQISEMD-HTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY 648
+V V L A D+ + + + + H +D + +SHG L G+ + +PD L Y
Sbjct: 172 TVEVEEKLTARDMESVLWKFAAREEHKSSDSTFLVFMSHGILDGICGTMHSEEEPDVLPY 231
Query: 649 -----YFTADKCPTLAGKPKLFFIQACQGDK------LDGGITL----SNTETDGXXXXX 783
F C +L KPK+ +QAC+G D L S + +
Sbjct: 232 DTIFRTFNNRNCLSLKDKPKVIIVQACRGANRGELWVSDSPPALADSFSQSSENLEEDAV 291
Query: 784 YRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNY 909
Y+ + DF+ S+ P SWR+ +GS F+ L + Y
Sbjct: 292 YKTHVEKDFIAFCSSTPHNVSWRDIKKGSLFITRLITCFQKY 333
>AL050391-1|CAB43686.2| 104|Homo sapiens hypothetical protein
protein.
Length = 104
Score = 52.0 bits (119), Expect = 4e-06
Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Frame = +1
Query: 445 LSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGEL-GMLYAKD 618
+ ++L GL +SV V NL A D+ ++ + +H +D + ++SHG L G+
Sbjct: 3 MKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVH 62
Query: 619 THYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 720
KPD L Y F C +L KPK+ +QAC+G
Sbjct: 63 DEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 101
>U97074-1|AAC51622.1| 480|Homo sapiens FLICE-like inhibitory
protein long form protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>U85059-1|AAB82648.1| 480|Homo sapiens MRIT-alpha-1 protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>BT006751-1|AAP35397.1| 480|Homo sapiens CASP8 and FADD-like
apoptosis regulator protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>BC001602-1|AAH01602.1| 480|Homo sapiens CASP8 and FADD-like
apoptosis regulator protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AF041461-1|AAB99793.1| 442|Homo sapiens I-FLICE isoform 4 protein.
Length = 442
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 244 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 303
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 304 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSFLEVDGPAMKN 363
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 364 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 413
>AF041460-1|AAB99792.1| 449|Homo sapiens I-FLICE isoform 3 protein.
Length = 449
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AF041459-1|AAB99791.1| 235|Homo sapiens I-FLICE isoform 2 protein.
Length = 235
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 18 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 77
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 78 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 137
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 138 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 187
>AF041458-1|AAB99790.1| 480|Homo sapiens I-FLICE protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AF015451-1|AAC16440.1| 462|Homo sapiens Usurpin-beta protein.
Length = 462
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AF015450-1|AAC16439.1| 480|Homo sapiens Usurpin-alpha protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AF010127-1|AAB64110.1| 480|Homo sapiens Casper protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AF009618-1|AAB70911.1| 480|Homo sapiens FLAME-1-gamma protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AF009616-1|AAB70909.1| 445|Homo sapiens FLAME-1 protein.
Length = 445
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 228 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 287
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 288 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 347
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 348 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 397
>AC007283-2|AAY24290.1| 480|Homo sapiens unknown protein.
Length = 480
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>AB038972-1|BAB32552.1| 462|Homo sapiens usurpin beta protein.
Length = 462
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 13/170 (7%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ---ACQGDKLDG------GITLSN 753
D TH ++ F D CP LAGKPK+FFIQ +G D G + N
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKN 382
Query: 754 TETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELR 903
E + ADF T ++ + S ++Q L ++LR
Sbjct: 383 VEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLR 432
>Y14039-1|CAA74366.1| 480|Homo sapiens CASH alpha protein protein.
Length = 480
Score = 49.2 bits (112), Expect = 3e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 708
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF041462-1|AAB99794.1| 348|Homo sapiens I-FLICE isoform 5 protein.
Length = 348
Score = 49.2 bits (112), Expect = 3e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 149 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 208
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 708
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 209 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 244
>AF005774-1|AAC15825.1| 480|Homo sapiens caspase-like apoptosis
regulatory protein protein.
Length = 480
Score = 47.6 bits (108), Expect = 9e-05
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +1
Query: 433 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 609
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 610 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 708
D TH ++ F + CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGESCPYLAGKPKMFFIQ 358
>AL512883-6|CAI12973.1| 266|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 266
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/59 (30%), Positives = 34/59 (57%)
Frame = +1
Query: 790 IPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+P +D + +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 185 LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 243
>AF110376-1|AAD13615.1| 266|Homo sapiens caspase-9S precursor
protein.
Length = 266
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/59 (30%), Positives = 34/59 (57%)
Frame = +1
Query: 790 IPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+P +D + +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 185 LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 243
>AF093130-1|AAD12248.1| 266|Homo sapiens caspase 9 short isoform
protein.
Length = 266
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/59 (30%), Positives = 34/59 (57%)
Frame = +1
Query: 790 IPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+P +D + +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 185 LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 243
>AB020979-1|BAA87905.1| 266|Homo sapiens caspase-9 protein.
Length = 266
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/59 (30%), Positives = 34/59 (57%)
Frame = +1
Query: 790 IPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+P +D + +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 185 LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 243
>AB015653-1|BAA78780.1| 266|Homo sapiens caspase-9 beta protein.
Length = 266
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/59 (30%), Positives = 34/59 (57%)
Frame = +1
Query: 790 IPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCEELRNYGTQRDILTLLTFVCQXVAL 966
+P +D + +ST PG+ SWR+ GSW++++L + + D+ +LL V V++
Sbjct: 185 LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSV 243
>AL627395-4|CAI16007.1| 220|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 220
Score = 44.4 bits (100), Expect = 8e-04
Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHN 495
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYND 113
>AL592546-6|CAI12641.1| 220|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 220
Score = 44.4 bits (100), Expect = 8e-04
Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +1
Query: 331 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHN 495
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYND 113
>AL512883-8|CAI12974.1| 254|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 254
Score = 35.9 bits (79), Expect = 0.28
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Frame = +1
Query: 493 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGEL-GMLYAKD-THYKPDNLWYYFTADK 666
N+ E + R + M D L A SH + G +Y D + + F
Sbjct: 184 NIDCEKLRRRFSSLHFMVEVKGD--LTAKASHLQFPGAVYGTDGCPVSVEKIVNIFNGTS 241
Query: 667 CPTLAGKPKLFFI 705
CP+L GKPKLFFI
Sbjct: 242 CPSLGGKPKLFFI 254
>AB209640-1|BAD92877.1| 144|Homo sapiens caspase 2 isoform 2
precursor variant protein.
Length = 144
Score = 35.1 bits (77), Expect = 0.50
Identities = 12/36 (33%), Positives = 24/36 (66%)
Frame = +1
Query: 787 RIPIHADFLIVFSTVPGYYSWRNTTRGSWFMQSLCE 894
R+P +D + ++ + G + RNT RGSW++++L +
Sbjct: 49 RLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQ 84
>AL831992-1|CAD89916.1| 798|Homo sapiens hypothetical protein
protein.
Length = 798
Score = 32.3 bits (70), Expect = 3.5
Identities = 16/45 (35%), Positives = 24/45 (53%)
Frame = +1
Query: 187 KMADEEKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVE 321
++A+ E+K + EQ NG DE D G H + R +KM +E
Sbjct: 80 RLAELEEKLPVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIE 124
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 148,724,050
Number of Sequences: 237096
Number of extensions: 3190851
Number of successful extensions: 5734
Number of sequences better than 10.0: 130
Number of HSP's better than 10.0 without gapping: 5188
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5546
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 16458822770
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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