Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_D11
(1276 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4; Euteleost... 263 6e-69
UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;... 253 8e-66
UniRef50_UPI0000519EC7 Cluster: PREDICTED: similar to Ecdysone-i... 226 1e-57
UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact... 196 1e-48
UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19; Magnol... 193 9e-48
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 183 1e-44
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 182 2e-44
UniRef50_A6NLX8 Cluster: L-lactate dehydrogenase; n=4; Eutheria|... 181 3e-44
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 180 5e-44
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 180 9e-44
UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila melanogaster|... 175 3e-42
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 171 3e-41
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 169 1e-40
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 169 2e-40
UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1; ... 167 4e-40
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 163 9e-39
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 162 2e-38
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 162 2e-38
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 159 2e-37
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 156 1e-36
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 155 2e-36
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 154 5e-36
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 153 7e-36
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 151 3e-35
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 151 4e-35
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 151 5e-35
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 150 7e-35
UniRef50_UPI00015B6427 Cluster: PREDICTED: similar to lactate de... 146 8e-34
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 144 3e-33
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 142 2e-32
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 141 4e-32
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 140 7e-32
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 135 2e-30
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 135 3e-30
UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to Ecdysone-i... 130 1e-28
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 130 1e-28
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 129 2e-28
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 128 2e-28
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 128 4e-28
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 127 7e-28
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 127 7e-28
UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphyloc... 125 3e-27
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 124 5e-27
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 122 2e-26
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 122 2e-26
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 122 2e-26
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 122 2e-26
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 122 2e-26
UniRef50_Q92BI0 Cluster: L-lactate dehydrogenase 2; n=18; Bacter... 122 3e-26
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 121 5e-26
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 120 6e-26
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 119 1e-25
UniRef50_Q185V1 Cluster: L-lactate dehydrogenase; n=3; Clostridi... 119 2e-25
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 118 3e-25
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 117 7e-25
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 117 7e-25
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 116 1e-24
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 116 2e-24
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 115 3e-24
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 115 3e-24
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 113 1e-23
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 113 1e-23
UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3; Lactoco... 112 2e-23
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 111 3e-23
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 111 4e-23
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 111 4e-23
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 111 5e-23
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 111 5e-23
UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3; Bifidob... 111 5e-23
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 109 2e-22
UniRef50_Q8IX04 Cluster: Ubiquitin-conjugating enzyme E2 variant... 109 2e-22
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 107 5e-22
UniRef50_A1C5Q5 Cluster: L-lactate dehydrogenase; n=4; Pezizomyc... 107 6e-22
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 106 1e-21
UniRef50_Q8RED8 Cluster: L-lactate dehydrogenase; n=3; Fusobacte... 105 3e-21
UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococ... 104 4e-21
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 104 4e-21
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 104 4e-21
UniRef50_UPI000023CE12 Cluster: hypothetical protein FG10444.1; ... 104 6e-21
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 104 6e-21
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 103 7e-21
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 103 7e-21
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 103 1e-20
UniRef50_Q92AZ3 Cluster: Lin1775 protein; n=13; Listeria|Rep: Li... 103 1e-20
UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 103 1e-20
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 102 2e-20
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 102 2e-20
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 102 2e-20
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 102 2e-20
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 102 2e-20
UniRef50_Q3U1V6 Cluster: Ubiquitin-conjugating enzyme E2 variant... 101 3e-20
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 100 7e-20
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 100 9e-20
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 99 1e-19
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 100 2e-19
UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene en... 100 2e-19
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 100 2e-19
UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5; Methanococcu... 99 2e-19
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 99 3e-19
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 99 3e-19
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 97 1e-18
UniRef50_A3ZZ88 Cluster: L-lactate/malate dehydrogenase; n=1; Bl... 95 3e-18
UniRef50_Q1FMY2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 95 5e-18
UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-... 94 6e-18
UniRef50_Q6YPG1 Cluster: Putative uncharacterized protein OJA121... 93 1e-17
UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-... 92 3e-17
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 91 4e-17
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 91 7e-17
UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; ... 89 2e-16
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 88 5e-16
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 87 7e-16
UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 86 2e-15
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 86 2e-15
UniRef50_Q38YI2 Cluster: Putative malate dehydrogenase; n=1; Lac... 84 9e-15
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 83 2e-14
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 83 2e-14
UniRef50_Q88ZG9 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 81 5e-14
UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 81 5e-14
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 80 1e-13
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 79 3e-13
UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 79 3e-13
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 78 6e-13
UniRef50_Q6ABQ3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 77 1e-12
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 76 2e-12
UniRef50_Q2FPC3 Cluster: Lactate/malate dehydrogenase; n=2; Meth... 75 3e-12
UniRef50_Q0P989 Cluster: L-lactate dehydrogenase; n=10; Campylob... 74 9e-12
UniRef50_Q034P5 Cluster: Enzyme with possible activities of L-2-... 73 1e-11
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 73 2e-11
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 71 6e-11
UniRef50_Q82R06 Cluster: Putative lactate dehydrogenase; n=1; St... 70 1e-10
UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH - ... 67 1e-09
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 64 6e-09
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 61 5e-08
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 58 6e-07
UniRef50_Q1U8H4 Cluster: L-lactate dehydrogenase; n=2; Lactobaci... 55 3e-06
UniRef50_Q8Y860 Cluster: Lmo1057 protein; n=11; Listeria|Rep: Lm... 52 3e-05
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 52 3e-05
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 50 2e-04
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 48 7e-04
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 47 0.001
UniRef50_Q039N1 Cluster: Malate/lactate dehydrogenase; n=1; Lact... 45 0.004
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 45 0.004
UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular org... 42 0.034
UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=12... 41 0.079
UniRef50_Q1WU75 Cluster: Lactate/malate dehydrogenase; n=1; Lact... 40 0.18
UniRef50_Q03QL8 Cluster: Malate/lactate dehydrogenase; n=1; Lact... 37 0.97
UniRef50_A2YRW8 Cluster: Putative uncharacterized protein; n=2; ... 36 1.7
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 36 3.0
UniRef50_A4XD44 Cluster: ABC transporter related; n=2; Salinispo... 35 5.2
UniRef50_Q6ZCA3 Cluster: Putative uncharacterized protein P0547A... 35 5.2
UniRef50_UPI0000F20185 Cluster: PREDICTED: hypothetical protein;... 34 6.8
UniRef50_P40557 Cluster: Putative protein disulfide-isomerase YI... 34 6.8
UniRef50_A5I533 Cluster: Putative malate/lactate dehydrogenase; ... 34 9.0
>UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4;
Euteleostomi|Rep: L-lactate dehydrogenase - Tetraodon
nigroviridis (Green puffer)
Length = 360
Score = 263 bits (645), Expect = 6e-69
Identities = 120/208 (57%), Positives = 160/208 (76%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
+KV + S+L +++ + +ALV +M ++LKGE+MDLQHGS F+ +KI +
Sbjct: 22 NKVTVVGVGQVGMACAISILLRDLADELALVDVMEDRLKGELMDLQHGSLFLKTSKIVAD 81
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
DYS+TA S++ VVTAGVRQ+EGESRL+LVQRN +V K IIPQ+IKYSP+ L++ S+PV
Sbjct: 82 KDYSVTANSRLVVVTAGVRQQEGESRLNLVQRNVNVFKSIIPQIIKYSPNCTLIVVSNPV 141
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D+LTYVTWK+SGLPKHRVIGSGT+LDSARFRYL+++RLGI +S +G+++GEHG +SVPV
Sbjct: 142 DVLTYVTWKLSGLPKHRVIGSGTNLDSARFRYLMAERLGIHASSFNGWVLGEHGDTSVPV 201
Query: 984 WSAVNIAGVRLXDLXNXIGTXXDPENWK 1067
WS N+AGV L L IGT D E W+
Sbjct: 202 WSGANVAGVNLQKLNPDIGTDDDKEEWR 229
>UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;
Eukaryota|Rep: L-lactate dehydrogenase C chain - Homo
sapiens (Human)
Length = 332
Score = 253 bits (619), Expect = 8e-66
Identities = 118/225 (52%), Positives = 159/225 (70%)
Frame = +3
Query: 399 KQLFQPVHAQVDATWSKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDL 578
+QL + + + + K+ I S+L +++ + +ALV + +KLKGEMMDL
Sbjct: 6 EQLIEKLIEDDENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKGEMMDL 65
Query: 579 QHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLI 758
QHGS F +KI S DYS++A S+I +VTAG RQ+EGE+RL LVQRN ++K IIP ++
Sbjct: 66 QHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIV 125
Query: 759 KYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSC 938
YSPD +++ S+PVDILTY+ WKISGLP RVIGSG +LDSARFRYL+ ++LG+ TSC
Sbjct: 126 HYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSC 185
Query: 939 HGYIIGEHGXSSVPVWSAVNIAGVRLXDLXNXIGTXXDPENWKXL 1073
HG+IIGEHG SSVP+WS VN+AGV L L +GT D E+WK +
Sbjct: 186 HGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNI 230
>UniRef50_UPI0000519EC7 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=2; Apocrita|Rep:
PREDICTED: similar to Ecdysone-inducible gene L3
CG10160-PA - Apis mellifera
Length = 409
Score = 226 bits (552), Expect = 1e-57
Identities = 102/193 (52%), Positives = 142/193 (73%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAG 674
+++ Q +T ++A+V KL+GE MD HG + + + +I TD+ IT+ SK+ V+ AG
Sbjct: 114 ALIFQKITAHVAMVDAFPKKLEGEGMDYCHGLSLIESPRIDFDTDFCITSNSKVIVLAAG 173
Query: 675 VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHR 854
RQ +GESRLDLVQRN+++LK IIP L+ YSP+ ++++ S+PVDIL+++TWKISGLP R
Sbjct: 174 ARQMKGESRLDLVQRNSEILKSIIPTLVGYSPNAVILVVSNPVDILSWLTWKISGLPASR 233
Query: 855 VIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXNX 1034
VIG+GT +DSARFR+L++DRLGIA +S H IIGEHG S VP+WS VN+AGV+ D+
Sbjct: 234 VIGTGTHVDSARFRFLIADRLGIAPSSVHATIIGEHGDSQVPLWSGVNVAGVQFRDILPN 293
Query: 1035 IGTXXDPENWKXL 1073
IG D E W L
Sbjct: 294 IGLETDEERWYEL 306
>UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4;
Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter
violaceus
Length = 330
Score = 196 bits (477), Expect = 1e-48
Identities = 91/188 (48%), Positives = 132/188 (70%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
+SML QN + + LV + K++GE+MDL HG F+ + +++ T + G + V+TA
Sbjct: 37 YSMLIQNTFDELVLVDIDRRKVEGEVMDLVHGIPFVEPSVVRAGT-LADCRGVDVVVITA 95
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G RQREGE+RL LVQRN ++ + +I +++++ P+ IL++ S+PVD++TYV K++GLP
Sbjct: 96 GARQREGETRLSLVQRNVEIFRGLIGEIMEHCPNAILLVVSNPVDVMTYVAMKLAGLPPS 155
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RVIGSGT LD+ARFRYLL++RL + S H YIIGEHG S VPVWS N+AG L ++
Sbjct: 156 RVIGSGTVLDTARFRYLLAERLRVDPRSLHAYIIGEHGDSEVPVWSRANVAGAFLSEIEP 215
Query: 1032 XIGTXXDP 1055
+GT DP
Sbjct: 216 AVGTPDDP 223
>UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19;
Magnoliophyta|Rep: L-lactate dehydrogenase A - Hordeum
vulgare (Barley)
Length = 356
Score = 193 bits (470), Expect = 9e-48
Identities = 83/172 (48%), Positives = 129/172 (75%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAG 674
++LTQN+ + IALV + +KL+GE +DLQH +AF+ +I S TD ++T S + +VTAG
Sbjct: 61 TILTQNLADEIALVDALPDKLRGEALDLQHAAAFLPRVRI-SGTDAAVTKNSDLVIVTAG 119
Query: 675 VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHR 854
RQ GE+RL+L+QRN + ++I+P + ++SPD +L++ S+PVD+LTYV WK+SG P R
Sbjct: 120 ARQIPGETRLNLLQRNVALYRKIVPPVAEHSPDALLLVVSNPVDVLTYVAWKLSGFPASR 179
Query: 855 VIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGV 1010
VIGSGT+LDS+RFR+L+++ L + Y++GEHG SSV +WS++++ G+
Sbjct: 180 VIGSGTNLDSSRFRFLIAEHLDVNAQDVQAYMVGEHGDSSVAIWSSISVGGM 231
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria|Rep:
L-lactate dehydrogenase - Clostridium tetani
Length = 316
Score = 183 bits (445), Expect = 1e-44
Identities = 83/182 (45%), Positives = 122/182 (67%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++++ + + + I +V + K KGE MDL HG +F+ I + DY T S I ++TA
Sbjct: 22 YALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAG-DYEDTKDSDIVIITA 80
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G + GE+RLDL+ +N ++ K I+P+++KYSP +IL++ S+PVDILTYVT+K+SG P+
Sbjct: 81 GAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVDILTYVTYKLSGFPQE 140
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RVIGSGT LD++RFRYLL + I + H YI+GEHG S + WS NIAG+ + D
Sbjct: 141 RVIGSGTVLDTSRFRYLLGEHFKIDVRNVHTYILGEHGDSEIAAWSLTNIAGISVEDYCK 200
Query: 1032 XI 1037
I
Sbjct: 201 DI 202
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|Rep:
L-lactate dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 321
Score = 182 bits (442), Expect = 2e-44
Identities = 82/177 (46%), Positives = 121/177 (68%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F++L + + I L+ K +GE MDL H F +I + +Y+ G+ + V+TA
Sbjct: 27 FALLQRRLAAEIVLIDANHKKAEGEAMDLNHAVPFGAATRIWAG-EYADCRGAAVTVITA 85
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G QR GE+RL L+ RN + +QI+P+++K++PD +L+IA++PVDI++Y ++KISGLP H
Sbjct: 86 GAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVDIISYASYKISGLPAH 145
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
RV+GSGT LD+ARFRYLL + S HG I+GEHG + VP+WS NIAG+RL +
Sbjct: 146 RVLGSGTILDTARFRYLLGQHFSVDARSVHGLILGEHGDTEVPIWSLANIAGIRLRE 202
>UniRef50_A6NLX8 Cluster: L-lactate dehydrogenase; n=4;
Eutheria|Rep: L-lactate dehydrogenase - Homo sapiens
(Human)
Length = 253
Score = 181 bits (441), Expect = 3e-44
Identities = 90/218 (41%), Positives = 132/218 (60%)
Frame = +3
Query: 342 WRXTTPTGIARTPTSWXPCKQLFQPVHAQVDATWSKVXIXXXXXXXXXXXFSMLTQNVTN 521
W T+ + +A + C +P H + KV I S+L + +++
Sbjct: 42 WLFTSVSKMATVKSELIECFTSEEPFHHR------KVSITGTGSVGMACATSILLKGLSD 95
Query: 522 NIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESR 701
+A V + KLKGE MDLQH S FM + I S DY +TA + ++TAG R+ +GE R
Sbjct: 96 ELAFVDLDEGKLKGETMDLQHDSPFMKMSNIVCSKDYLVTANPHLVIITAGARREKGEMR 155
Query: 702 LDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLD 881
+LV++N + K +I +++ SP L+I S+PVDILTYV WK+S PK+RVIGSG +LD
Sbjct: 156 FNLVRQNVAIFKLMISSIVQQSPLCKLIIVSNPVDILTYVAWKLSAFPKNRVIGSGCNLD 215
Query: 882 SARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAV 995
+ RF++ + +LGI + SC G+I+GEHG SSVPVWS +
Sbjct: 216 TVRFQFFIGQKLGIHSESCRGWILGEHGDSSVPVWSGM 253
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 180 bits (439), Expect = 5e-44
Identities = 81/215 (37%), Positives = 130/215 (60%)
Frame = +3
Query: 429 VDATWSKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA 608
VD K+ I ++L + + + + + + K E D+ HG+AF+ N
Sbjct: 28 VDGHRVKIVIVGSGYTGVAIGIAILFKRLASELVFIDVNEELAKAEAEDISHGAAFLGNP 87
Query: 609 KIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVI 788
KI + DYS+ + +CV+T G R + L+++N ++ K +IP++ KY+P++IL+I
Sbjct: 88 KIIGTKDYSLARDATVCVITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLI 147
Query: 789 ASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGX 968
+ PVDIL+Y K+SG P HRV+G GT LDS RF+Y ++ +LGI+ +S +I E+G
Sbjct: 148 VTAPVDILSYAAMKLSGFPPHRVVGLGTFLDSCRFQYFIAQKLGISASSVQASVICENGP 207
Query: 969 SSVPVWSAVNIAGVRLXDLXNXIGTXXDPENWKXL 1073
+SVP+WSAV + G++L D+ IGT DPE+W L
Sbjct: 208 TSVPIWSAVTVMGIKLKDINKDIGTKADPESWGEL 242
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 180 bits (437), Expect = 9e-44
Identities = 82/203 (40%), Positives = 128/203 (63%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
+K+ I F+++ + + I +V + +K E MDL G+AF+ + I+S
Sbjct: 7 NKISIIGAGFVGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSG 66
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
DY+ T S I ++TAGV + GE+RLD++ +N + + I+P+++KYSP++IL++ S+PV
Sbjct: 67 -DYADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPV 125
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
DILTY+T+K+SG PK RVIGSGT LD++R +Y+LS+ I + H YIIGEHG S +
Sbjct: 126 DILTYITYKLSGFPKERVIGSGTVLDTSRLKYMLSEHFDIDARNVHTYIIGEHGDSEITA 185
Query: 984 WSAVNIAGVRLXDLXNXIGTXXD 1052
WS NIAG + + + D
Sbjct: 186 WSLTNIAGANVEEYCKTVCANCD 208
>UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila melanogaster|Rep:
AT22132p - Drosophila melanogaster (Fruit fly)
Length = 361
Score = 175 bits (425), Expect = 3e-42
Identities = 76/190 (40%), Positives = 124/190 (65%), Gaps = 1/190 (0%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV 677
+L +N+T N+ ++ + K E +D QH SAF+ +A++ D + + S + ++TAG
Sbjct: 67 LLLRNLTKNLVILDINYELAKAEALDFQHASAFLSDARVVPCGDSTNSKDSDVVIITAGA 126
Query: 678 RQR-EGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHR 854
R + SRL +Q+ ++LK+ +P+L++ SP+ +I S+P D++TY +I+ LPKHR
Sbjct: 127 RPSGKDRSRLAAMQKTVEILKKAVPKLVELSPNATFIIISNPADVMTYAVQRITNLPKHR 186
Query: 855 VIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXNX 1034
+G LD+ RFR L+++RL + + HGY+IGEHG S+VPVWS+V+IAG+RL D+
Sbjct: 187 CFTTGCHLDTVRFRNLIANRLRLPPSQVHGYVIGEHGASAVPVWSSVSIAGIRLNDVVKN 246
Query: 1035 IGTXXDPENW 1064
+ DPENW
Sbjct: 247 LACGDDPENW 256
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 171 bits (416), Expect = 3e-41
Identities = 84/175 (48%), Positives = 112/175 (64%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
+SM+ Q V LV + K +GE MDL H F + S Y+ + + V+TA
Sbjct: 22 YSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPTKVWSGSYADCKDADLVVITA 81
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G+ Q+ GE+RLDLV++NT + KQI+ ++ D I +IA++PVDILTYVTWK SGLPK
Sbjct: 82 GLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPVDILTYVTWKESGLPKE 141
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
RVIGSGT LDSARFRY+L D L + + H YI+GEHG + +PVWS I +L
Sbjct: 142 RVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIVGEHGDTELPVWSHATIGVQKL 196
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 169 bits (411), Expect = 1e-40
Identities = 79/178 (44%), Positives = 113/178 (63%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F++L Q++T + ++ + +K G+ MDL HG F N +Y + I + A
Sbjct: 23 FALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPTKTWYGNYDDCKEADIVCICA 82
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G Q+ GE+RLDLV++N + K ++ Q++ D I +IA++PVDILTY TWK SGLPK
Sbjct: 83 GANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIFLIATNPVDILTYATWKFSGLPKE 142
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
RVIGSGT LDS RFR+LL + IA + H +IIGEHG + +PVWS +I GV + +L
Sbjct: 143 RVIGSGTILDSGRFRFLLGEYFDIAPANVHAHIIGEHGDTELPVWSHADIGGVPVEEL 200
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 169 bits (410), Expect = 2e-40
Identities = 81/193 (41%), Positives = 117/193 (60%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
SKV I F+M + N + L+ + K GE MD+ HG FM + +
Sbjct: 8 SKVAIIGAGFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAG 67
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
DYS + VVTAG ++ GE+RLDL ++N + K++ ++KY ++++ S+PV
Sbjct: 68 -DYSDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPV 126
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
DI+TY+ K SGLP +VIGSGT LDS RFRYLLS++LG+ + HGYIIGEHG S +P+
Sbjct: 127 DIITYMIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVKNVHGYIIGEHGDSQLPL 186
Query: 984 WSAVNIAGVRLXD 1022
WS +IAG + +
Sbjct: 187 WSCTHIAGKNINE 199
>UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 323
Score = 167 bits (407), Expect = 4e-40
Identities = 80/208 (38%), Positives = 122/208 (58%), Gaps = 1/208 (0%)
Frame = +3
Query: 447 KVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSST 626
KV I +++L I L+ + +K +GE+MDL H + F+ +I +
Sbjct: 14 KVVIVGAGYVGSTTAYTLLMNRAAAEIVLIDVDKDKTEGEVMDLVHAAPFLHQTRIWAG- 72
Query: 627 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKY-SPDTILVIASDPV 803
DY G+ + ++TAG Q+ G+SR++L Q N + K+I+P+++++ SPD +L+++++PV
Sbjct: 73 DYEDCKGASVIILTAGANQKPGQSRMELAQSNWGIFKEIVPKVVQHASPDALLLVSANPV 132
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D++TY K SG P H VIGSGT LDSARF L L I S H +IGEHG S +PV
Sbjct: 133 DVMTYAAVKFSGFPAHSVIGSGTSLDSARFAGELGKHLNIDPRSLHAVVIGEHGESELPV 192
Query: 984 WSAVNIAGVRLXDLXNXIGTXXDPENWK 1067
WS ++G+R+ D GT D E K
Sbjct: 193 WSLATVSGMRVEDYCRQTGTPWDEETKK 220
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 - Bifidobacterium
longum
Length = 320
Score = 163 bits (396), Expect = 9e-39
Identities = 71/177 (40%), Positives = 115/177 (64%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F+ + + I L + +++ E++D+QHGS+F I S D I + + V+TA
Sbjct: 25 FAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGSDDPEICRDADMVVITA 84
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G RQ+ G+SRL+LV ++LK I+P L+K +P+ I ++ ++PVDI T+V K++GLP++
Sbjct: 85 GPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVDIATHVAQKLTGLPEN 144
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
++ GSGT+LDSAR R+L++ + G+ + H YI GEHG S VP+W + I GV + D
Sbjct: 145 QIFGSGTNLDSARLRFLIAQQTGVNVKNVHAYIAGEHGDSEVPLWESATIGGVPMCD 201
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 162 bits (394), Expect = 2e-38
Identities = 79/179 (44%), Positives = 114/179 (63%), Gaps = 2/179 (1%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXM--MANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVV 665
F+++ Q + + ++ + + K G+ +DL H AF KI ++ YS A + + V+
Sbjct: 24 FALVNQGIAQELGIIEIPQLHEKAVGDALDLSHALAFTSPKKIYAA-QYSDCADADLVVI 82
Query: 666 TAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLP 845
TAG Q+ GE+RLDLV +N + K I+ Q+++ I ++A++PVD+LTY TWK SG P
Sbjct: 83 TAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFP 142
Query: 846 KHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
K RVIGSGT LDSARFR L+++L + S H YI+GEHG S VWS NIAGV L +
Sbjct: 143 KERVIGSGTSLDSARFRQALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEE 201
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 162 bits (393), Expect = 2e-38
Identities = 74/199 (37%), Positives = 118/199 (59%)
Frame = +3
Query: 414 PVHAQVDATWSKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSA 593
P +V + KV I ++ L + +AL + K++ E++DL HGS
Sbjct: 9 PASPEVRSARPKVSIIGAGSVGTAIAYACLIRGSAGTLALYDTNSAKVRAEVLDLNHGSQ 68
Query: 594 FMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPD 773
F+ ++ S D ++TAGS I VVTAG +Q G+SRLDL N + + + PQL+++SPD
Sbjct: 69 FVPECRVGGSDDIAVTAGSAIVVVTAGAKQHPGQSRLDLAAANVAMAQTLTPQLLEHSPD 128
Query: 774 TILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYII 953
+++ ++PVD++TY + ++ G+GT LDS+RFRYL++ R IA + H +I
Sbjct: 129 AVVIFVTNPVDVVTYAASSVVDAQPGQIFGTGTVLDSSRFRYLVAQRAAIAVGNVHALVI 188
Query: 954 GEHGXSSVPVWSAVNIAGV 1010
GEHG S +P+WS ++I GV
Sbjct: 189 GEHGDSEIPLWSTLSIGGV 207
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 159 bits (385), Expect = 2e-37
Identities = 84/182 (46%), Positives = 111/182 (60%), Gaps = 1/182 (0%)
Frame = +3
Query: 447 KVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAF-MXNAKIQSS 623
KV I +SM+ Q + N + LV + K +GE +DL G ++ N + +
Sbjct: 7 KVAIIGTGFVGTSIAYSMINQGIANELILVDIDKAKSEGEAIDLLDGVSWGQENVNVWAG 66
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
DY + I V+TAG Q+ G+SRLDLV N +++K I+ ++K D ILVIAS+PV
Sbjct: 67 -DYQDCQDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPV 125
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D+LTYV W+ SGLP RVIG+GT LD+ RFR LS RL I + HGYIIGEHG S V V
Sbjct: 126 DVLTYVAWQASGLPVSRVIGTGTTLDTTRFRKELSQRLAIDPRNVHGYIIGEHGDSEVAV 185
Query: 984 WS 989
WS
Sbjct: 186 WS 187
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase - Borrelia
burgdorferi (Lyme disease spirochete)
Length = 316
Score = 156 bits (378), Expect = 1e-36
Identities = 75/169 (44%), Positives = 106/169 (62%), Gaps = 1/169 (0%)
Frame = +3
Query: 501 LTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGV 677
+ ++ + + ++ + NK KGE+MDL HG F+ N + T Y A + I V+TAG+
Sbjct: 25 IDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLKKNINVLFGT-YKDCANADIVVITAGL 83
Query: 678 RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRV 857
Q+ GE+RLDLV +N+ + K II ++ D I V+AS+PVDI+TYVT K S P H+V
Sbjct: 84 NQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVDIMTYVTMKYSKFPIHKV 143
Query: 858 IGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIA 1004
IG+GT LD++R RY LSD + T + H YI+GEHG SS W IA
Sbjct: 144 IGTGTILDTSRLRYFLSDHFNVNTQNIHSYIMGEHGDSSFATWDETKIA 192
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 155 bits (376), Expect = 2e-36
Identities = 73/178 (41%), Positives = 112/178 (62%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F++L + + L+ + + +G+ +DL HG+ F A I + DY+ GS + +V A
Sbjct: 17 FALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYAG-DYADLKGSDVVIVAA 75
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
GV Q+ GE+RL L+ RN V+K+I + KY+PD+I+++ ++PVD+LTY K SG+
Sbjct: 76 GVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVDVLTYFFLKESGMDPR 135
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+V GSGT LD+AR R L++ G + S H Y+IGEHG S VPVWS I G+ L ++
Sbjct: 136 KVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIGEHGDSEVPVWSGAMIGGIPLQNM 193
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 154 bits (373), Expect = 5e-36
Identities = 73/189 (38%), Positives = 113/189 (59%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F++L + I ++ + K +GE MDL H + ++ DY + V+TA
Sbjct: 37 FTLLLSGLAAEIVIIDLNKKKAEGEAMDLNHAAPLSHETRVYLG-DYKDCKDATAVVITA 95
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G Q+ GE+R+DL++ N + K+I+ ++ KY+ D IL++A++PVD+LTY T K++G P
Sbjct: 96 GKNQKPGETRMDLLKANISIFKEILREVTKYTKDAILLVATNPVDVLTYATLKLTGFPAE 155
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RVIGSGT +D+ARF+YL+ G+ S + IIGEHG S + VWS +IAG+ L D
Sbjct: 156 RVIGSGTIIDTARFQYLIGKLYGLDPQSVNADIIGEHGDSELAVWSHASIAGLSLADFCE 215
Query: 1032 XIGTXXDPE 1058
T D +
Sbjct: 216 ESETKYDEQ 224
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 153 bits (372), Expect = 7e-36
Identities = 71/183 (38%), Positives = 116/183 (63%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++++ + + + + L+ K +GE MD+ HG F I + +Y A + + ++TA
Sbjct: 21 YTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIYAG-EYEDIADASVVIITA 79
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G Q+ GE+RLDLVQ+N +++ II ++ + + + IL+I S+PVDILT V + SG PK
Sbjct: 80 GANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVDILTEVALRESGFPKE 139
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RVIGSGT LD+AR +Y++S++L + + + H +I+GEHG S + WS NI G++L D
Sbjct: 140 RVIGSGTVLDTARLKYIISEKLDVDSRNVHAFIVGEHGDSELAAWSCANIYGIKLQDFAK 199
Query: 1032 XIG 1040
G
Sbjct: 200 MRG 202
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase - Oceanobacillus
iheyensis
Length = 321
Score = 151 bits (367), Expect = 3e-35
Identities = 73/180 (40%), Positives = 108/180 (60%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F+++ Q VT +A++ + A+K G++MDL HG AF + +Y + I + A
Sbjct: 25 FALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPSLTNVWLGEYGDCKDADIVCICA 84
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G Q+ GE+RLDLV++N + K+I+ ++ + I +IA++PVDILT SGLP H
Sbjct: 85 GANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIFLIATNPVDILTQAVISFSGLPPH 144
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RVIGSGT LD+AR RY L + ++ + H YIIGEHG + +P+WS I V L N
Sbjct: 145 RVIGSGTTLDTARLRYELGEYFHLSPKNIHAYIIGEHGDTELPLWSTATIGTVPLLTYLN 204
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 151 bits (366), Expect = 4e-35
Identities = 70/176 (39%), Positives = 114/176 (64%), Gaps = 1/176 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++M Q++ + I L+ + +GE MDL HG + ++ +Y+ + ++I V++A
Sbjct: 21 YAMFNQSLASEILLLDQDTRRAEGEAMDLMHGQQLVGGITCRA-VEYAALSNAQIIVLSA 79
Query: 672 GVRQRE-GESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
G Q+ E+RL L+QRN ++ ++II QL K++P+ ILV+A++PVD+LTY+ ++S P
Sbjct: 80 GASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDVLTYICQELSSRPN 139
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
R++G+GT LD+ARFR LL G+ S H YI+GEHG S VP+WS I G ++
Sbjct: 140 RRILGTGTLLDTARFRALLGRHYGVDPRSVHAYILGEHGDSEVPIWSNATIGGQKI 195
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 151 bits (365), Expect = 5e-35
Identities = 75/206 (36%), Positives = 118/206 (57%), Gaps = 1/206 (0%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQS 620
SK+ + ++++ Q +T+++A++ + K G + DL H + N ++
Sbjct: 16 SKIVLIGAGDVGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHAVPWSHHNTRVTV 75
Query: 621 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDP 800
T + +C+ AG Q+ GE+RLDLV +NT + K I+ ++ + + I ++AS+P
Sbjct: 76 GTYEDCRDAAMVCIC-AGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNP 134
Query: 801 VDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVP 980
VDIL+Y TWK SG+ RVIGSGT LD+ARFRY L +A TS H Y+IGEHG + +P
Sbjct: 135 VDILSYATWKFSGMDSSRVIGSGTILDTARFRYALGRYFDLAPTSVHAYVIGEHGDTELP 194
Query: 981 VWSAVNIAGVRLXDLXNXIGTXXDPE 1058
V SA ++AG + IG D +
Sbjct: 195 VLSAGSVAGTSIHHRLEMIGESADED 220
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 150 bits (364), Expect = 7e-35
Identities = 72/175 (41%), Positives = 110/175 (62%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F+ + + V + I LV + + + E D+ H F +A+I + Y +G+ + ++
Sbjct: 8 FACIMRGVASEIVLVDLDTARAQAEAEDIAHAVPFSVSARIVAG-GYDDLSGADVVILAC 66
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
GV Q+ GESRL+L+ RN +V + ++ + + +PD IL+IAS+PVDI+T+VT +SGLP
Sbjct: 67 GVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVDIMTHVTQALSGLPAG 126
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
RVIGSGT LD+ARFR+LL L IA S H Y++GEHG + V W+A V +
Sbjct: 127 RVIGSGTILDTARFRWLLGRHLNIAPRSVHAYVLGEHGDTEVLAWTAARAGSVSI 181
>UniRef50_UPI00015B6427 Cluster: PREDICTED: similar to lactate
dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to lactate dehydrogenase - Nasonia vitripennis
Length = 352
Score = 146 bits (355), Expect = 8e-34
Identities = 66/189 (34%), Positives = 118/189 (62%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV 677
+L + + + L+ + E D+ + F+ + KI++STDYS + +CV+ AG
Sbjct: 56 LLFKRLAAELILMDENPEMARAEAEDIAAAAVFLGSPKIRASTDYSEARDATLCVIAAGR 115
Query: 678 RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRV 857
+QR+ ++Q+N +LK+++P L KY+P+++L++ S+PVD+L+++ K+SG P RV
Sbjct: 116 QQRDEADAEAVLQQNALLLKELVPSLTKYAPNSVLLVVSEPVDVLSHLAMKLSGFPSQRV 175
Query: 858 IGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXNXI 1037
+G GT LD+ R ++ L+ LG+ + H +I E G +SVP+WSA ++ G++L D+ I
Sbjct: 176 LGLGTLLDNCRLQHELAKELGVNQAAVHSMVIAESGPTSVPIWSAASVMGMKLKDIDKDI 235
Query: 1038 GTXXDPENW 1064
G DPE +
Sbjct: 236 G---DPEGF 241
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: L-lactate dehydrogenase -
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579
/ NCIMB8303)
Length = 309
Score = 144 bits (350), Expect = 3e-33
Identities = 70/187 (37%), Positives = 116/187 (62%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++ + + N+I L+ A + +GE MDL A + +I+S Y G++I VVTA
Sbjct: 18 YAAAIKRLANDIVLIDANAARAEGESMDLADAMALVGPVQIRSG-GYEQCEGARIVVVTA 76
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G +Q G+SRLDLV+ N + + I+ +++Y+ D + ++A++PVD+LT+V ++G+
Sbjct: 77 GAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVARTVTGVAPG 136
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RVIGSGT LDSARFR +++ LG+ H +I+GEHG S V +WS N++G+ + ++
Sbjct: 137 RVIGSGTVLDSARFRGHVAEILGVDVRGVHAHIVGEHGDSEVALWSRANVSGIPVAEMCA 196
Query: 1032 XIGTXXD 1052
G D
Sbjct: 197 RRGIAYD 203
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 142 bits (344), Expect = 2e-32
Identities = 66/193 (34%), Positives = 111/193 (57%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
SK+ + ++ L + ++L + +K++ E+ DL HG+ F A +
Sbjct: 11 SKISVVGAGSVGSSLAYACLIRGSAGLVSLYDIAKDKVEAEVADLAHGTQFTP-ASVMGG 69
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
D TA S + +TAG RQ+ G++RLDL N ++L+ ++PQL++ SP+ + V+ ++P
Sbjct: 70 ADVHDTADSDVVFITAGARQKPGQTRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPC 129
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D+LT V + +GLP +RV +GT LD++R R+L+ + H I+GEHG S P+
Sbjct: 130 DVLTVVAQEATGLPANRVFSTGTMLDTSRLRWLIRQWANVEQRHVHATIVGEHGDSEFPL 189
Query: 984 WSAVNIAGVRLXD 1022
WS NI+GV + D
Sbjct: 190 WSTANISGVPIRD 202
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|Rep:
L-lactate dehydrogenase - Deinococcus radiodurans
Length = 304
Score = 141 bits (341), Expect = 4e-32
Identities = 63/177 (35%), Positives = 113/177 (63%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F+++ + + + LV ++ + E D+ H + ++ +S A +++ ++TA
Sbjct: 17 FALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVWHG-GHSELADAQVVILTA 75
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G Q+ GESRLDL+++N D+ ++++PQ+ + +PD +L++ S+PVD+LT + +++ P
Sbjct: 76 GANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPVDLLTDLATQLA--PGQ 133
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
VIGSGT LDSARFR+L++ G+ T HGY++GEHG S V WS+ +AG+ + D
Sbjct: 134 PVIGSGTVLDSARFRHLMAQHAGVDGTHAHGYVLGEHGDSEVLAWSSAMVAGMPVAD 190
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|Rep:
L-lactate dehydrogenase - Treponema denticola
Length = 315
Score = 140 bits (339), Expect = 7e-32
Identities = 75/200 (37%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
Frame = +3
Query: 429 VDATWSKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA 608
+D KV + +++ + IA+ M N +G+ +DL G F+
Sbjct: 1 MDEKKRKVTVVGAGAVGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQV 60
Query: 609 KIQSS--TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 782
I + TDY A S I VVTAG +Q+ GE+R+DL++RN ++ I + + ++
Sbjct: 61 DIHAGDKTDY---ADSDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVM 117
Query: 783 VIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEH 962
+I S+PVDILT K SG + RVIGSGT LD+ARFRY LS G+ + HGYI+GEH
Sbjct: 118 LIVSNPVDILTRAALKASGWERGRVIGSGTVLDTARFRYTLSKECGVDARNIHGYILGEH 177
Query: 963 GXSSVPVWSAVNIAGVRLXD 1022
G S WS ++AG R+ +
Sbjct: 178 GDSEFAAWSMTSVAGRRIDE 197
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 135 bits (327), Expect = 2e-30
Identities = 68/183 (37%), Positives = 110/183 (60%)
Frame = +3
Query: 429 VDATWSKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA 608
+D KV I FS++ + + +V ++ +G++ DL+ +AF
Sbjct: 1 MDKKQRKVVIVGDGSVGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNAT 60
Query: 609 KIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVI 788
I + +Y+ + I V+TAGV ++ GESRLDL+ RNT +L+ I+ ++ + VI
Sbjct: 61 NIHTG-EYADARDADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVI 119
Query: 789 ASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGX 968
+S+PVDILT +T ++SG P+HRVIG+GT LD+AR R L+ +L +ATT+ ++GEHG
Sbjct: 120 SSNPVDILTSMTQRLSGFPRHRVIGTGTSLDTARLRVALAQKLNVATTAVDAAVLGEHGD 179
Query: 969 SSV 977
SS+
Sbjct: 180 SSI 182
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 135 bits (326), Expect = 3e-30
Identities = 63/172 (36%), Positives = 101/172 (58%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
+S++ Q + + L+ + + GE MDL H F + Y I ++TA
Sbjct: 22 YSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITA 81
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G + G+SRLD + + +++ ++ +++ D I ++AS+PVDI+TY WK+SGLP++
Sbjct: 82 GPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYQVWKLSGLPRN 141
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
RVIG+GT LDS+R R +LS+ L + S HGY +GEHG S + WS V + G
Sbjct: 142 RVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGG 193
>UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Ecdysone-inducible
gene L3 CG10160-PA - Apis mellifera
Length = 368
Score = 130 bits (313), Expect = 1e-28
Identities = 63/206 (30%), Positives = 113/206 (54%)
Frame = +3
Query: 447 KVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSST 626
KV I ++L + + + + L+ ANK E D+QH F+ + ++
Sbjct: 50 KVSIVGVGKIGIACAIAILMRRMASEVCLIDHDANKASAEAEDIQHVGFFLGCPLVTGTS 109
Query: 627 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVD 806
+ S S + ++ GE++ V+ N V K+IIP + +++ ++L+I + P D
Sbjct: 110 EISTVKESAVVIICTP-ETPPGENQN--VKHNLKVFKKIIPAIARFAAKSVLLIVTRPAD 166
Query: 807 ILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVW 986
+++Y+ WK+SG P +RV+G GT +D AR + +S RL +A +S IG G +VP+W
Sbjct: 167 VMSYIAWKLSGFPSNRVLGIGTLIDCARLQDFVSRRLNVARSSVSCMTIGSQGDMAVPLW 226
Query: 987 SAVNIAGVRLXDLXNXIGTXXDPENW 1064
S++++ G++L D+ + IG DPE W
Sbjct: 227 SSISVGGMKLRDINSRIGEQDDPEKW 252
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 130 bits (313), Expect = 1e-28
Identities = 62/194 (31%), Positives = 109/194 (56%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
SKV + FS++TQ+V + + L+ + K GE+MDL H ++ + +
Sbjct: 8 SKVIVVGAGLVGTSTAFSLITQSVCDEVMLIDINRAKAHGEVMDLCHSIEYLNRNVLVTE 67
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
DY+ + I V+TAG + G+SRLD + + D++ I+ ++K + I ++ ++PV
Sbjct: 68 GDYTDCKDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPV 127
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D + +++SGLPK +V+G+GT +DSAR ++ + D L + S Y +GEHG S +
Sbjct: 128 DSIAQYVYQLSGLPKQQVLGTGTAIDSARLKHFIGDILHVDPRSIQAYTMGEHGDSQMCP 187
Query: 984 WSAVNIAGVRLXDL 1025
WS V + G + D+
Sbjct: 188 WSLVTVGGKNIMDI 201
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 129 bits (311), Expect = 2e-28
Identities = 70/176 (39%), Positives = 103/176 (58%), Gaps = 1/176 (0%)
Frame = +3
Query: 492 FSML-TQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVT 668
FS L + N + + LV +K G+ DL + KI + T Y A + + V+T
Sbjct: 23 FSFLQSTNEVDELVLVDRTKSKAVGDAADLADITPLTNPVKIYAGT-YEDAADADVVVIT 81
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG+ ++ GE+RLDLV +NT +LK II ++K + VI+S+PVDILT + +ISG PK
Sbjct: 82 AGIPRKPGETRLDLVNKNTTILKSIIKPIVKSGFTGVFVISSNPVDILTTIAQRISGFPK 141
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
RVIG+GT LDS R R LLS +L ++ ++GEHG +S ++ + I G L
Sbjct: 142 ERVIGTGTSLDSMRLRVLLSKKLHLSVNVIDALMLGEHGDTSFAAFNEITIGGKAL 197
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 128 bits (310), Expect = 2e-28
Identities = 66/193 (34%), Positives = 109/193 (56%), Gaps = 2/193 (1%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAF--MXNAKIQSSTDYSITAGSKICVV 665
++M+T+ + L+ + KG MD+ A +KI++ T Y+ G+ + +V
Sbjct: 18 YTMITKGIDAEYVLIDINTEFAKGHAMDMSDAIALNSTTGSKIRTGT-YADAKGADLLIV 76
Query: 666 TAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLP 845
AG Q++GE+RL+++ N+ ++K I ++ K + ++ S+PVDIL V K++ P
Sbjct: 77 AAGRPQKQGETRLEMIADNSKIMKDIALEIKKSGFNGFTIVISNPVDILATVFQKVTNFP 136
Query: 846 KHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
K +V+ SGT LD++RFR LS++ G+ T S HG++IGEHG SV V+S + I RL D
Sbjct: 137 KEKVMSSGTFLDTSRFRKFLSEKTGVPTNSVHGFVIGEHGDKSVVVFSRMQIGFSRLDDF 196
Query: 1026 XNXIGTXXDPENW 1064
D W
Sbjct: 197 LKSKALTEDDLKW 209
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeosphaeria
nodorum|Rep: L-lactate dehydrogenase - Phaeosphaeria
nodorum (Septoria nodorum)
Length = 326
Score = 128 bits (308), Expect = 4e-28
Identities = 61/170 (35%), Positives = 106/170 (62%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++++ Q++ + LV + L G++ DL ++ + K++S T + + I V+TA
Sbjct: 24 YTLILQSICTEVLLVDPKTSLLDGQVRDLSDATS--RSTKVRSGT-HQEAGQADIVVITA 80
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G +Q+ GESRL L+ RN ++L I + S T+L++ ++PVDIL Y +SGLP++
Sbjct: 81 GAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDILVYFARMMSGLPEN 140
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNI 1001
+V+G+GT LDSAR R +L+ + G++ +S Y++GEHG S WS+ +I
Sbjct: 141 QVLGTGTSLDSARLRGVLAGKAGVSPSSIDAYVLGEHGDSQFVAWSSASI 190
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 127 bits (306), Expect = 7e-28
Identities = 61/196 (31%), Positives = 105/196 (53%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
SKV I F M+ +V +++ L+ + K E DLQH + +
Sbjct: 6 SKVVIVGTGSVGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKD 65
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
+Y + I V+ A + G++RLD++++ ++ I+P ++K I+V+ ++PV
Sbjct: 66 GEYEECNDADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPV 125
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D+++Y K+SGLP +VIG+GT LDSAR +Y L+D + + S H +GEHG S +
Sbjct: 126 DVMSYYVHKLSGLPASKVIGTGTALDSARLKYHLADVMSVDPQSVHALCMGEHGDSQIIP 185
Query: 984 WSAVNIAGVRLXDLXN 1031
WS + + G + D+ N
Sbjct: 186 WSQITVGGKKFLDIIN 201
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostridium
acetobutylicum|Rep: L-lactate dehydrogenase 2 -
Clostridium acetobutylicum
Length = 320
Score = 127 bits (306), Expect = 7e-28
Identities = 64/181 (35%), Positives = 106/181 (58%), Gaps = 4/181 (2%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX--NAKIQSSTDYSITAGSKICVVT 668
S+L+ N+ + + ++ + NK KGE +D H ++F N K+++ +Y A ++I V+T
Sbjct: 23 SVLSLNLLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVRAG-NYEDCADAQIIVIT 81
Query: 669 AGVRQREGES--RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGL 842
AG + + RL L N V I+ + KY+ D I+++ ++PVDI TY
Sbjct: 82 AGPSLKPDDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVDIATYYCQNNFDY 141
Query: 843 PKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
PK+++IG+GT LD+AR R ++ + + + + HGY++GEHG SS WS VNIAG+
Sbjct: 142 PKNKIIGTGTLLDTARMRKIIGKKYNVDSKNVHGYVLGEHGGSSFTSWSDVNIAGIPFNQ 201
Query: 1023 L 1025
L
Sbjct: 202 L 202
>UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphylococcus
haemolyticus JCSC1435|Rep: L-lactate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 318
Score = 125 bits (301), Expect = 3e-27
Identities = 61/177 (34%), Positives = 102/177 (57%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAG 674
+++ + + + +A++ + +K K ++ DL H + F N Y + I V+ A
Sbjct: 21 AIVAKGLVDEMAIIDIDEDKAKADVWDLNHATPFGDNFVNVHVGQYEDFKDADIVVICAS 80
Query: 675 VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHR 854
+ +GE+RL L++ N D+ +I +++ D V+ S+PVDI++YV ++S PK++
Sbjct: 81 AKLAKGETRLKLLEDNVDIFVPMIQRIVDSGFDGYFVLPSNPVDIMSYVVKRVSNFPKNK 140
Query: 855 VIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+IGSGT LD+ARF++ LS +A + IIGEHG S V VWS IAG + DL
Sbjct: 141 IIGSGTSLDTARFQFFLSREFDVAPNQVYAPIIGEHGDSQVAVWSHAQIAGEPVLDL 197
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 124 bits (299), Expect = 5e-27
Identities = 64/188 (34%), Positives = 106/188 (56%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
SKV I ++++ +N+ I +V + + ++ +++DL ++ S
Sbjct: 5 SKVAIVGAGAVGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGS 64
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
+ + A I V+TAG +QREGE R L++RN VL+ II + PD ++++ ++PV
Sbjct: 65 AEEAGQAD--IVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPV 122
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
DILT++ +SGLP ++VIGSGT LD+ R R L D + S H +++GEHG S +
Sbjct: 123 DILTHIAKTLSGLPPNQVIGSGTYLDTTRLRVHLGDVFDVNPQSVHAFVLGEHGDSQMIA 182
Query: 984 WSAVNIAG 1007
W A +I G
Sbjct: 183 WEAASIGG 190
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 122 bits (295), Expect = 2e-26
Identities = 59/179 (32%), Positives = 105/179 (58%), Gaps = 3/179 (1%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANK--LKGEMMDLQH-GSAFMXNAKIQSSTDYSITAGSKICVVT 668
ML +I L+ AN+ KG+ +D+ G + ++ ++DY T S + V+T
Sbjct: 19 MLAMKGLGDIVLLDTQANENPTKGKALDIMEAGPLTRSSVRVTGTSDYQDTLDSDVVVIT 78
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG+ ++ G SR +L N ++ ++ Q++++SP++ L+I S+PVDI+TYV +K SG +
Sbjct: 79 AGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVDIMTYVAFKESGFKR 138
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+R+IG LDSARFRY ++ L ++ G+++G HG VP+ ++ G+ + L
Sbjct: 139 NRIIGQSGVLDSARFRYFVASELKVSAEDVTGFVLGVHGDDMVPLVRYCSVHGIPIQQL 197
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobacillus
casei ATCC 334|Rep: L-lactate dehydrogenase -
Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 122 bits (295), Expect = 2e-26
Identities = 60/177 (33%), Positives = 103/177 (58%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F+ LT V ++ ++ + +++G++ DL + I +++ Y + I V+TA
Sbjct: 21 FNCLTTGVGQSLGIIDVNEKRVQGDVEDLSDALPYTSQKNIYAAS-YEDCKYADIIVITA 79
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G+ Q+ G++RL L+ N ++K+I ++ + +++AS+PVD+L + + SGLP++
Sbjct: 80 GIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDVLAELVLQESGLPRN 139
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
+V+GSGT LDSAR R + R + HGYI+GEHG S PVW NI G + D
Sbjct: 140 QVLGSGTALDSARLRSEIGLRYNVDARIVHGYIMGEHGDSEFPVWDYTNIGGKPILD 196
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|Rep:
L-lactate dehydrogenase - Blastopirellula marina DSM 3645
Length = 313
Score = 122 bits (295), Expect = 2e-26
Identities = 67/177 (37%), Positives = 98/177 (55%), Gaps = 2/177 (1%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F++ + IAL+ + A+ G +DL HG+ + + I S I IC+ TA
Sbjct: 18 FALQCGGIAREIALLDLNADLAGGHALDLLHGAPSVADQVITSGGYEHIPDSDVICI-TA 76
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIK--YSPDTILVIASDPVDILTYVTWKISGLP 845
G+R++ ESRLDL+ RN D+ I+ + D I + S+PVDILTY+ + LP
Sbjct: 77 GLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVDILTYLAAQRLNLP 136
Query: 846 KHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
RVIG GT LD+ RFR L++ + + T I+GEHG S +PVWSA + G+ L
Sbjct: 137 TSRVIGLGTQLDTIRFRALIAQEMKLPPTQVKALILGEHGDSMLPVWSAATVNGLPL 193
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 122 bits (295), Expect = 2e-26
Identities = 54/173 (31%), Positives = 104/173 (60%), Gaps = 1/173 (0%)
Frame = +3
Query: 501 LTQNVTNNIALVXMMANKLKGEMMD-LQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV 677
+ +N ++ ++ + +G+ +D L+ G + +I S +Y GS + VVTAG
Sbjct: 25 IVENGLADVVILDVREGMAQGKALDILESGPLLGFDTRIVGSGNYETIEGSSVVVVTAGF 84
Query: 678 RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRV 857
++ G SR DL+ +N D++ ++ ++ K++PD+++++ ++P+D++ Y+ WK++G P+ RV
Sbjct: 85 SRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMDLMAYILWKVTGFPRERV 144
Query: 858 IGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
IG G LDS+RF Y +S+ + ++ ++G HG VP+ IAGV L
Sbjct: 145 IGMGGALDSSRFAYFVSEVTNTSVSNIQTMVMGGHGDDMVPLLEFSTIAGVSL 197
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 122 bits (294), Expect = 2e-26
Identities = 61/164 (37%), Positives = 100/164 (60%), Gaps = 7/164 (4%)
Frame = +3
Query: 555 LKGEMMDLQHGSAFMX-NAKIQSST------DYSITAGSKICVVTAGVRQREGESRLDLV 713
+KG+ +D++ A M +A+++ T Y GS I V+TAG +R G SR DL+
Sbjct: 48 VKGKALDMKQMLAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLL 107
Query: 714 QRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARF 893
+ N ++ I ++ +Y+PD I+++ ++PVD++TYV +K+ PK+RV+G LDSARF
Sbjct: 108 EANIRIISVIADRIKRYAPDAIVIVVTNPVDVMTYVAYKLLNFPKNRVMGMAGVLDSARF 167
Query: 894 RYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+ +S+ L ++ H Y+IG HG VP+ S N+ G+ L DL
Sbjct: 168 KTFISEELMVSPKDIHAYVIGGHGDEMVPLISISNVGGIPLKDL 211
>UniRef50_Q92BI0 Cluster: L-lactate dehydrogenase 2; n=18;
Bacteria|Rep: L-lactate dehydrogenase 2 - Listeria
innocua
Length = 311
Score = 122 bits (293), Expect = 3e-26
Identities = 62/172 (36%), Positives = 100/172 (58%), Gaps = 1/172 (0%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAG 674
+ + Q + LV + +++G DL +AFM S + S A I V+T
Sbjct: 21 AFVNQKFVEELILVDLNKERVEGNRKDLADAAAFMSGKMDISVREASDCADVDIAVITVT 80
Query: 675 VRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
+EG++RLD ++ + ++ I+P+++K I +IA++P DI+TY WK+SGLP+
Sbjct: 81 AGPLKEGQTRLDELRSTSRIVASIVPEMMKGGFKGIFLIATNPCDIITYQVWKLSGLPRE 140
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
+V+G+G LD+ R R LL+++L IA S +I+GEHG S PVWS +I G
Sbjct: 141 QVLGTGVWLDTTRLRRLLAEKLDIAAQSIDAFILGEHGDSQFPVWSHSSIYG 192
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 121 bits (291), Expect = 5e-26
Identities = 57/155 (36%), Positives = 99/155 (63%), Gaps = 1/155 (0%)
Frame = +3
Query: 549 NKLKGEMMDLQHG-SAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNT 725
+KL+G D+ +A +A+I + + + V+TAG+ ++ G++RLDL + N
Sbjct: 40 DKLRGLRRDILDSLAAAQKDAEITIGCERDDYVDADVIVMTAGIPRKPGQTRLDLTKDNA 99
Query: 726 DVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLL 905
++K+ + + + +P+ I+++ ++PVD+LTYV K+SGLPK+RVIG GT LDS RF+ L+
Sbjct: 100 AIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVALKVSGLPKNRVIGLGTHLDSMRFKVLI 159
Query: 906 SDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGV 1010
+ + + H IIGEHG + VPV S+ ++ G+
Sbjct: 160 AKHFNVHMSEVHTRIIGEHGDTMVPVISSTSVGGI 194
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 120 bits (290), Expect = 6e-26
Identities = 59/167 (35%), Positives = 98/167 (58%), Gaps = 1/167 (0%)
Frame = +3
Query: 525 IALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICV-VTAGVRQREGESR 701
+ L +K +G++ D++ + +I S Y A S I + VTAGV+ + G++R
Sbjct: 33 VVLFDRTLSKAEGQVWDIEDSIPLLKEMEIIPSNQYEDLADSDIIIIVTAGVQPKLGQTR 92
Query: 702 LDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLD 881
LD + N ++++ I +L + +P++I++I S+PVD+LT + S ++ + GSGT LD
Sbjct: 93 LDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVDVLTRIAQATSTRAENLIFGSGTVLD 152
Query: 882 SARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
+AR RY L +L +A H Y+IGEHG S VWS+ I G+ L +
Sbjct: 153 TARLRYQLGKQLNVAKQDIHAYVIGEHGDSQFVVWSSAFIGGILLTE 199
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 119 bits (287), Expect = 1e-25
Identities = 58/178 (32%), Positives = 106/178 (59%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++ + + + + I +V +K GE +D+ AF A+I+ + + TAG+ I V+TA
Sbjct: 17 YTAMLKGLAHEIVMVDAARDKAHGEALDMLQCLAFAPPARIRHG-EMADTAGADIVVITA 75
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G+ ++ E R+ L+ RN ++ ++ Q + YSP+ I+ + ++P+D++T + +++SGLP +
Sbjct: 76 GIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLAYQVSGLPAN 135
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
RVIG GT LD+AR+R L+ Y++GEHG + V + S + + GV L L
Sbjct: 136 RVIGMGTVLDTARYRSYLAVAFDADARDIDAYVVGEHGETMVCLTSQITVRGVPLTAL 193
>UniRef50_Q185V1 Cluster: L-lactate dehydrogenase; n=3;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
difficile (strain 630)
Length = 322
Score = 119 bits (286), Expect = 2e-25
Identities = 62/183 (33%), Positives = 104/183 (56%), Gaps = 5/183 (2%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
FS++TQ V + + ++ + +K K + +DL +++ + +S S I V++
Sbjct: 22 FSLITQGVCDELFMIDIDESKSKAQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISV 81
Query: 672 -----GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKIS 836
G +R+ +RLDL++ ++K I+ ++ D I V+ S+PVD++T W+ S
Sbjct: 82 ADSSEGPLRRQNTTRLDLLRPTIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKS 141
Query: 837 GLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
G PK++VIG+GT LDS R R +LS+ GIA S Y +GEHG S + WS V+I G +
Sbjct: 142 GFPKNKVIGTGTALDSTRLRRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPI 201
Query: 1017 XDL 1025
D+
Sbjct: 202 LDM 204
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 118 bits (284), Expect = 3e-25
Identities = 57/170 (33%), Positives = 101/170 (59%), Gaps = 1/170 (0%)
Frame = +3
Query: 519 NNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGVRQREGE 695
N I L+ ++ +GE +D+ H S+ + + + S +Y GS + +VTAG+ ++ G
Sbjct: 25 NKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSNEYKDIEGSDLIIVTAGLPRKPGM 84
Query: 696 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTD 875
+R L++ N ++ +I ++ KY+PD+I+++ ++P+D +TYV WK +G P+ RVIG
Sbjct: 85 TREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLDAMTYVMWKATGFPRERVIGFSGV 144
Query: 876 LDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
LD+ R + + +LGI+ S ++G+HG S PV S + GV L L
Sbjct: 145 LDAGRLAFYAAKKLGISPASILPIVLGQHGESMFPVPSKSYVHGVPLSKL 194
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase - Reinekea
sp. MED297
Length = 319
Score = 117 bits (281), Expect = 7e-25
Identities = 55/165 (33%), Positives = 96/165 (58%), Gaps = 2/165 (1%)
Frame = +3
Query: 519 NNIALVXMMANKLKGEMMDLQHGSA--FMXNAKIQSSTDYSITAGSKICVVTAGVRQREG 692
+ + L+ K +GEMMD H ++ F N ++++ DYS+ + I V+TAG + +EG
Sbjct: 26 SELVLIDQQIGKAEGEMMDFGHANSLTFSKNIRLRAGDDYSLLTDADIVVITAGAQIKEG 85
Query: 693 ESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGT 872
++R DL + N+ + I ++ +P+ IL++ ++P DI TY + +G P RVI +G
Sbjct: 86 QTRDDLAEINSRITVDIAQKIETVAPNAILLVVTNPCDIATYFITQNTGFPADRVISAGC 145
Query: 873 DLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
+D+AR L+S+++ + + GYI+GEHG W V +AG
Sbjct: 146 IIDTARLMKLVSEKVDVDPKNVSGYILGEHGSHCFMPWGLVGVAG 190
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 117 bits (281), Expect = 7e-25
Identities = 62/173 (35%), Positives = 99/173 (57%), Gaps = 1/173 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXN-AKIQSSTDYSITAGSKICVVT 668
F+ L + IALV + + GE MDL H +A + KI DYS+ GS+I VVT
Sbjct: 17 FTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGGADYSLLKGSEIIVVT 76
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG+ ++ G +RLDL +N ++K I ++++ +P++ +++ ++P+D++TY+ WK SG P+
Sbjct: 77 AGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMDVMTYIMWKESGKPR 136
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
+ V G G LDS R + L + A +IIGEHG S S + G
Sbjct: 137 NEVFGMGNQLDSQRLKERLYN--AGARNIRRAWIIGEHGDSMFVAKSLADFDG 187
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 116 bits (279), Expect = 1e-24
Identities = 54/157 (34%), Positives = 94/157 (59%), Gaps = 2/157 (1%)
Frame = +3
Query: 513 VTNNIALVXMMANKLKGEMMDLQHGSAFMX--NAKIQSSTDYSITAGSKICVVTAGVRQR 686
V + + ++ + +G+ MD+ + + + + DY+ TA S + V+T+G+ ++
Sbjct: 25 VADEVVMLDVKEGVSEGKAMDMMQTAQLLGFDTTIVGCTNDYAQTANSDVVVITSGIPRK 84
Query: 687 EGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGS 866
G +R +L+ N ++K + L+KYSP+ I+V+ S+P+D +TY+ K GLPK+RVIG
Sbjct: 85 PGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDTMTYLALKSLGLPKNRVIGM 144
Query: 867 GTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSV 977
G LDS+RF+Y LS LG G +IG HG +++
Sbjct: 145 GGALDSSRFKYFLSQALGCNANEVEGMVIGGHGDTTM 181
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 116 bits (278), Expect = 2e-24
Identities = 61/190 (32%), Positives = 102/190 (53%)
Frame = +3
Query: 438 TWSKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQ 617
T +KV + +S + Q + L+ + +G +D+Q A +
Sbjct: 4 TSNKVVLVGTGAVGMSFIYSAVNQGLAEEYVLIDVNTKAAEGNAIDIQDTMAVLDKPFTI 63
Query: 618 SSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASD 797
+ Y + + V+TAG QR GE+RL+L+ N+ ++K I + + + VIAS+
Sbjct: 64 KAGTYEDCKDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASN 123
Query: 798 PVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSV 977
P D+LT V +++G +H V+G+GT LDSAR R L++++L +A S + YI+GEHG SSV
Sbjct: 124 PCDVLTTVYQQVTGYDEHSVVGAGTTLDSARLRRLVAEKLNVAPKSVNAYIMGEHGDSSV 183
Query: 978 PVWSAVNIAG 1007
+S + G
Sbjct: 184 AAYSKATVMG 193
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides sp.
(strain CBDB1)
Length = 307
Score = 115 bits (276), Expect = 3e-24
Identities = 56/169 (33%), Positives = 98/169 (57%), Gaps = 1/169 (0%)
Frame = +3
Query: 522 NIALVXMMANKLKGEMMDL-QHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGES 698
++ ++ ++ +G+ +D+ Q S I S DY+ TAGS+I V+TAG+ ++ G +
Sbjct: 27 DVVMLDVVEGIPQGKALDISQSASVLGFRHTITGSNDYAQTAGSEIVVITAGIARKPGMT 86
Query: 699 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDL 878
R +L+ N ++ ++ +KYSP+ LV+ S+PVD +TY+ WK+SGLP+ RV+G L
Sbjct: 87 REELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLAWKLSGLPRKRVVGLSGVL 146
Query: 879 DSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
D R ++ LG+ ++ ++GEHG S V + + G L +L
Sbjct: 147 DGGRLATFVARELGVNPSAVSPCVMGEHGGSMVVMSRFTLVNGKPLSEL 195
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 115 bits (276), Expect = 3e-24
Identities = 58/178 (32%), Positives = 98/178 (55%), Gaps = 1/178 (0%)
Frame = +3
Query: 522 NIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGVRQREGES 698
++ L + +G+ +D+ S +AK + DY+ G+ + +VTAGV ++ G S
Sbjct: 29 DVVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGANDYAAIEGADVVIVTAGVPRKPGMS 88
Query: 699 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDL 878
R DL+ N V++Q+ + KY+P+ ++ ++P+D + + K SGLP H+V+G L
Sbjct: 89 RDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMVWALQKFSGLPAHKVVGMAGVL 148
Query: 879 DSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXNXIGTXXD 1052
DSARFRY LS+ ++ +++G HG S VP+ +AG+ L DL T D
Sbjct: 149 DSARFRYFLSEEFNVSVEDVTAFVLGGHGDSMVPLARYSTVAGIPLSDLVKMGWTSQD 206
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 113 bits (271), Expect = 1e-23
Identities = 53/141 (37%), Positives = 85/141 (60%)
Frame = +3
Query: 603 NAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 782
N ++ T GS I V+T+GV ++ ++RLDL N ++K Q+ + +P+ IL
Sbjct: 59 NTRVTFGTTPKELRGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAIL 118
Query: 783 VIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEH 962
++ ++PVDI+T V K SG+ HRV G GT LDS R + L++ + + H IIGEH
Sbjct: 119 LVVTNPVDIMTTVALKYSGMMPHRVFGLGTHLDSMRLKACLAEFFNVHVSEIHTRIIGEH 178
Query: 963 GXSSVPVWSAVNIAGVRLXDL 1025
G + VP+WSA + G+++ +L
Sbjct: 179 GDTMVPMWSATTVGGIQIDNL 199
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 113 bits (271), Expect = 1e-23
Identities = 55/162 (33%), Positives = 92/162 (56%), Gaps = 6/162 (3%)
Frame = +3
Query: 558 KGEMMDLQHGSAF------MXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQR 719
+G+ +D+Q G+ + S++Y GS + VVTAG+ ++ G SR DL +
Sbjct: 41 EGKALDIQEGAPHWGYDLDVVGFSTSDSSNYKNMEGSDVIVVTAGMARKPGMSREDLFDK 100
Query: 720 NTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRY 899
N +++ + + KYSPD+I+V+ S+P DI+ Y KISG+ R++G G LDS+RFR
Sbjct: 101 NVEIIADVSKNIKKYSPDSIIVVVSNPADIMAYALQKISGVDPQRIMGLGGSLDSSRFRT 160
Query: 900 LLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
L+ L ++ + ++IG HG VP ++AG+ + L
Sbjct: 161 FLAKELDVSVEDVNAFVIGGHGDDMVPFIRYSSVAGIPIEKL 202
>UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3; Lactococcus
lactis|Rep: L-lactate dehydrogenase 3 - Lactococcus
lactis subsp. lactis (Streptococcus lactis)
Length = 323
Score = 112 bits (269), Expect = 2e-23
Identities = 57/178 (32%), Positives = 102/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA-KIQSSTDYSITAGSKICVVTA 671
+++ ++ + IA++ +K +DL H ++ A K + DYS + + I V++A
Sbjct: 23 NLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNAAPKNIYAADYSDVSDADIVVLSA 82
Query: 672 GVRQR---EGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGL 842
+ RL L++ ++++ I + + D I ++AS+PVD+L V ++SGL
Sbjct: 83 NAPSATFGKNPDRLQLLENKVEMIRDITRKTMDAGFDGIFLVASNPVDVLAQVVAEVSGL 142
Query: 843 PKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
PKHRVIG+GT L+++R R +++++L I S HGY++ EHG SS WS V + + L
Sbjct: 143 PKHRVIGTGTLLETSRMRQIVAEKLQINPKSIHGYVLAEHGKSSFAAWSNVTVGAIPL 200
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 111 bits (268), Expect = 3e-23
Identities = 58/158 (36%), Positives = 89/158 (56%), Gaps = 1/158 (0%)
Frame = +3
Query: 555 LKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDV 731
LKG D A N ++ +T AGS I V+TAG + G++RLDL N +
Sbjct: 42 LKGLAQDFADSFAARGTNIRVTWTTSLKDVAGSDIVVITAGTPRGPGQNRLDLALGNARI 101
Query: 732 LKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSD 911
+ + + +PDT +++ ++PVD++T V K SGL ++V G GT LDS R + L++
Sbjct: 102 IAPMARTIGTIAPDTKIIMVTNPVDVMTCVALKYSGLKPNQVFGLGTHLDSMRLKSLIAS 161
Query: 912 RLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+ + H IIGEHG S VP+WSA I G+++ +L
Sbjct: 162 YFKVHVSEVHTRIIGEHGDSMVPLWSATTIGGIKISNL 199
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 111 bits (267), Expect = 4e-23
Identities = 52/167 (31%), Positives = 95/167 (56%), Gaps = 1/167 (0%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAG 674
++++ V + L+ + N + MDL +A + + I +Y + I V+TAG
Sbjct: 19 LISRKVCKKVTLIDINKNLAIAKAMDLAQMAAVLNLDIDIFGGDNYELLKDFDIVVITAG 78
Query: 675 VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHR 854
+++G+SR DL N ++ + K++P +I+++ ++P+DI+ YV +K SG +H+
Sbjct: 79 FARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMVYVAFKESGFARHK 138
Query: 855 VIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAV 995
VIG +LDSARFRY +S +LG+ C G +G H S + + S++
Sbjct: 139 VIGMAGELDSARFRYYMSQKLGLNVAQCFGKCVGMHNNSMICLESSI 185
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 111 bits (267), Expect = 4e-23
Identities = 55/149 (36%), Positives = 88/149 (59%)
Frame = +3
Query: 561 GEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQ 740
G+ D HG A+ N +++ Y TAGS + V+TAG+ ++ G++R+DL N +++
Sbjct: 44 GQAADTNHGIAYDSNTRVRQG-GYEDTAGSDVVVITAGIPRQPGQTRIDLAGDNAPIMED 102
Query: 741 IIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLG 920
I L +++ D I + S+PVD+L ++ + +VIG G LDSARFRY+LS+
Sbjct: 103 IQSSLDEHNDDYISLTTSNPVDLLNRHLYEAGDRSREQVIGFGGRLDSARFRYVLSEEFD 162
Query: 921 IATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
+ G I+GEHG + VPV+S V + G
Sbjct: 163 APVQNVEGTILGEHGDAQVPVFSKVRVDG 191
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate dehydrogenase
- Cenarchaeum symbiosum
Length = 302
Score = 111 bits (266), Expect = 5e-23
Identities = 53/174 (30%), Positives = 103/174 (59%), Gaps = 1/174 (0%)
Frame = +3
Query: 507 QNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGVRQ 683
+ + + I L+ ++ +GE MD+ H A + +++ S DYS GS I VV AG +
Sbjct: 21 RRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSNDYSDMEGSDIVVVVAGAGR 80
Query: 684 REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIG 863
+ G +R+DL++ N ++K ++ ++ +++ D++++ ++P+D +TY+ +K SG K+RV G
Sbjct: 81 KPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLDPITYIAYKTSGFEKNRVFG 140
Query: 864 SGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
G LD +RFR + + G + S ++GEHG + +P+ ++G+ L L
Sbjct: 141 MGGMLDLSRFRQFIHEATGYSRDSIRALVMGEHGENMLPLPRFSTVSGIPLLSL 194
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 111 bits (266), Expect = 5e-23
Identities = 58/176 (32%), Positives = 103/176 (58%), Gaps = 1/176 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++ +T+ + + ++ + G + DLQ S+ N + +YS ++A
Sbjct: 20 YAAMTRALGSEYMIIDINEKAKVGNVFDLQDASSSCPNFGKVVAGEYSQLKDYDFIFISA 79
Query: 672 GVRQREG-ESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
G Q++G E+RL L++ N +++K I ++ K + + +IAS+PVDI++Y K++G
Sbjct: 80 GRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVDIMSYTYLKVTGFEP 139
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
++VIGSGT LDSAR RY ++ + +++ Y+IGEHG SSV + S+ IAG+ L
Sbjct: 140 NKVIGSGTLLDSARLRYAIATKYQMSSKDVQAYVIGEHGDSSVSIISSAKIAGLSL 195
>UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3;
Bifidobacterium longum|Rep: L-lactate dehydrogenase 1 -
Bifidobacterium longum
Length = 316
Score = 111 bits (266), Expect = 5e-23
Identities = 53/188 (28%), Positives = 98/188 (52%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
+KV I F ++T + N + L+ A K GE DL GS F +
Sbjct: 7 NKVVIVGTGQVGATAAFGIVTHGLCNELVLIDCSAAKALGEARDLDDGSEFQDRHVKVRA 66
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
DY+ + I V+T G + +R+ + ++ +++ ++ D ++V+ S+PV
Sbjct: 67 GDYADCKDADIVVITVGRKPPANSNRMAELGFTVGLVGEVVDNVMASGFDGVIVMVSNPV 126
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D++ + WK SGLP+ +V+G+GT LD++R + ++ + G+ + G+++GEHG S
Sbjct: 127 DVMAWYAWKRSGLPRTQVLGTGTALDTSRLKTIIGEETGLDPRNVGGFVMGEHGDSQFTA 186
Query: 984 WSAVNIAG 1007
WS V++ G
Sbjct: 187 WSTVSLGG 194
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 109 bits (262), Expect = 2e-22
Identities = 55/179 (30%), Positives = 104/179 (58%), Gaps = 1/179 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHG-SAFMXNAKIQSSTDYSITAGSKICVVT 668
FS L + + + I L+ + +GE MD+ H S + +++ S ++ GS I VV
Sbjct: 17 FSAL-KRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSNNFEDMKGSNIVVVV 75
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG ++ G +R+DL++ N ++K ++ + KY+ D++++ ++P+D + Y+T+K+SG +
Sbjct: 76 AGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLDPMAYITYKVSGFDR 135
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
RV G G LD +RFR + + G + S +IGEHG + +P+ +++G+ L L
Sbjct: 136 SRVFGMGGMLDLSRFRQFIHEATGHSRDSIRALVIGEHGENMLPLPRFSSVSGIPLPSL 194
>UniRef50_Q8IX04 Cluster: Ubiquitin-conjugating enzyme E2 variant 3;
n=15; Euteleostomi|Rep: Ubiquitin-conjugating enzyme E2
variant 3 - Homo sapiens (Human)
Length = 471
Score = 109 bits (261), Expect = 2e-22
Identities = 61/184 (33%), Positives = 103/184 (55%)
Frame = +3
Query: 438 TWSKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQ 617
T +K+ + ++ + + + + L+ + + KG MDL+ + + N +I
Sbjct: 181 TVNKITVVGGGELGIACTLAISAKGIADRLVLLDL-SEGTKGATMDLEIFN--LPNVEI- 236
Query: 618 SSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASD 797
S D S +A SK+ + T +S LD+VQ N D+ + ++P L YS ++L++AS
Sbjct: 237 -SKDLSASAHSKVVIFTVN-SLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQ 294
Query: 798 PVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSV 977
PV+I+TYVTWK+S P +RVIG G +LDS R +Y++++ L T+ ++IGE G V
Sbjct: 295 PVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKV 354
Query: 978 PVWS 989
WS
Sbjct: 355 LTWS 358
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 107 bits (258), Expect = 5e-22
Identities = 57/172 (33%), Positives = 95/172 (55%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
+++ Q + + I LV K K MD+ +F ++ I DYS + I V++A
Sbjct: 21 YALAIQGICDEIVLVDKDRTKAKSHSMDIADSVSFFNSSVIVRCGDYSDCKDADIIVISA 80
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
GV + G++RLD++ + + ++ I+ L K I++ ++P DI+ K +GLPK+
Sbjct: 81 GVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPADIIADFVRKATGLPKN 140
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
RV +GT LD+AR R ++D IA S G+ +GEHG SS+ +S + I G
Sbjct: 141 RVFSTGTSLDTARMRRTVADLCNIAPQSVIGFAMGEHGDSSMVPFSNLTIFG 192
>UniRef50_A1C5Q5 Cluster: L-lactate dehydrogenase; n=4;
Pezizomycotina|Rep: L-lactate dehydrogenase - Aspergillus
clavatus
Length = 312
Score = 107 bits (257), Expect = 6e-22
Identities = 58/176 (32%), Positives = 97/176 (55%), Gaps = 2/176 (1%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA--KIQSSTDYSITAGSKICVVT 668
+++ +V + LV + ++ +L S A +I++ T Y I V+T
Sbjct: 25 ALILGSVARELLLVDVKIPLRNAQVQELSDVSNMSGGAETRIRAGT-YEEAGQCDIVVIT 83
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG + GE+ + + RN ++++IIP + + PDTIL++ S+PVD+LT V ++SGLP
Sbjct: 84 AGSKYSVGETSVQHMYRNMGIVQKIIPAMRPFRPDTILLVVSNPVDLLTTVAQQLSGLPP 143
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
+V+GSGT L+S R R L++ G+A S Y++G HG WS + G+ L
Sbjct: 144 TQVLGSGTLLESVRLRGLVAKTTGVAPDSVDLYVLGVHGIGETVAWSTATVGGLSL 199
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 106 bits (255), Expect = 1e-21
Identities = 53/183 (28%), Positives = 96/183 (52%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
+S + + + ++ + G +D + SA + +YS + V+TA
Sbjct: 22 YSCMNRGLAEQYGIIDINDKLSVGHSLDFEDASAANNHNFSVGKIEYSDLKDYDVVVITA 81
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G Q+ GE+RL++V N ++ I + K + ++ ++PVD++T++ +G K+
Sbjct: 82 GRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVDVMTFIYQHETGFDKN 141
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RVI SGT LDSAR R+ +S +L + S +++GEHG SSV V+SA ++G ++
Sbjct: 142 RVISSGTSLDSARLRFEISKKLKVHPKSVQAFVLGEHGDSSVSVYSAATVSGKSFNEIVK 201
Query: 1032 XIG 1040
G
Sbjct: 202 ERG 204
>UniRef50_Q8RED8 Cluster: L-lactate dehydrogenase; n=3; Fusobacterium
nucleatum|Rep: L-lactate dehydrogenase - Fusobacterium
nucleatum subsp. nucleatum
Length = 318
Score = 105 bits (251), Expect = 3e-21
Identities = 62/193 (32%), Positives = 101/193 (52%), Gaps = 1/193 (0%)
Frame = +3
Query: 447 KVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSST 626
KV I SML Q V + + L+ ++ K K +D +F+ + I
Sbjct: 6 KVGIVGIGHVGSHCALSMLLQGVCDEMVLMDIIPEKAKAHAIDCMDTISFLPHRAI--IR 63
Query: 627 DYSITAGSKICVVTAGVRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
D I SK+ V+ V + E RL+ ++ + + +K +P ++K + I V ++PV
Sbjct: 64 DGGIQELSKMDVIVISVGSLTKNEQRLEELKGSLEAIKSFVPDVVKAGFNGIFVTITNPV 123
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
DI+TY ++SG PK+RVIG+GT LDSAR + +LS+ I + Y++GEHG + +
Sbjct: 124 DIVTYFVRELSGFPKNRVIGTGTGLDSARLKRILSEVTNIDSQVIQAYMLGEHGDTQIAN 183
Query: 984 WSAVNIAGVRLXD 1022
+S+ I GV D
Sbjct: 184 FSSATIQGVPFLD 196
>UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305|Rep:
Lactate dehydrogenase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 310
Score = 104 bits (250), Expect = 4e-21
Identities = 52/173 (30%), Positives = 95/173 (54%), Gaps = 2/173 (1%)
Frame = +3
Query: 510 NVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA--KIQSSTDYSITAGSKICVVTAGVRQ 683
N+ + I L+ A+ GE +D H + A KI+S +T I + +
Sbjct: 24 NLFSEIILIDDRADVASGEALDHIHSQGLINTAHIKIRSGVYQDLTDADFIVIAASEATD 83
Query: 684 REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIG 863
+ R L Q N D++K I+ Q+ + + + ++++ S+PVD + Y +I P H++IG
Sbjct: 84 KNNGDRTLLAQGNHDIIKGIMSQIAEVTQEAVVILISNPVDSMVYFANQID-YPAHKIIG 142
Query: 864 SGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
+GT L+++RF+ +++D I + ++IGEHG ++PVWS V+I G+ L +
Sbjct: 143 TGTALETSRFKTIIADHYQIDPNNVEAFVIGEHGQHAIPVWSKVHIHGMELSE 195
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial malate-dehydrogenase
- Toxoplasma gondii
Length = 470
Score = 104 bits (250), Expect = 4e-21
Identities = 49/169 (28%), Positives = 95/169 (56%), Gaps = 1/169 (0%)
Frame = +3
Query: 522 NIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGVRQREGES 698
++ + ++ + +G+ +DL + + + + S DYS+ + + +VTAGV ++ G S
Sbjct: 183 DVVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGSNDYSVLKDADVIIVTAGVPRKPGMS 242
Query: 699 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDL 878
R DL+ N ++ Q+ + +Y P+ ++ ++P+D++ Y+ + GLP H+V G L
Sbjct: 243 RDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYILREKCGLPPHKVCGMAGVL 302
Query: 879 DSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
DSAR R LS+RL ++ H ++G HG + VP+ + G+ L +L
Sbjct: 303 DSARLRTFLSERLNVSVDDIHALVMGGHGDTMVPLPRFTTVGGIPLPEL 351
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 104 bits (250), Expect = 4e-21
Identities = 49/115 (42%), Positives = 73/115 (63%)
Frame = +3
Query: 645 GSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVT 824
GS I V+TAG+ +REG SR DL+ N +LK+ + +Y+ D+I+++ S+PVD LTY T
Sbjct: 88 GSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYAKDSIIIVVSNPVDTLTYAT 147
Query: 825 WKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWS 989
K++G RVIG LDSARF+ + +++GI+ ++G HG VPV S
Sbjct: 148 IKLTGFEPRRVIGMAGVLDSARFKNFVKEKIGISNADIRTLVLGTHGDLMVPVTS 202
>UniRef50_UPI000023CE12 Cluster: hypothetical protein FG10444.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG10444.1
- Gibberella zeae PH-1
Length = 309
Score = 104 bits (249), Expect = 6e-21
Identities = 52/194 (26%), Positives = 102/194 (52%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
S+V I +++ ++ + + LV + + ++ DL + ++ S
Sbjct: 5 SRVAIVGVGEVGGAVAYNLTLNSMASELLLVDLDPSARNAQIEDLSDVTYSTNSSTRVRS 64
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
Y A + V+TA + G++ +D RNT +L+ ++ + + DT+L+I +DPV
Sbjct: 65 ATYHEAAQCDLVVITAASKHMLGQTTIDYTSRNTSMLRGVMEAMKPFRADTVLLIVADPV 124
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D+LT + ++SGLP+ +V G+GT LD+ R R +++ R ++ + +++G HG V V
Sbjct: 125 DLLTSLAKQMSGLPESQVFGTGTALDTYRLRGMIASRALVSPYTVDAFVVGRHGEEQVVV 184
Query: 984 WSAVNIAGVRLXDL 1025
WS+ I V + D+
Sbjct: 185 WSSATIGAVPIQDV 198
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 104 bits (249), Expect = 6e-21
Identities = 54/176 (30%), Positives = 96/176 (54%), Gaps = 1/176 (0%)
Frame = +3
Query: 501 LTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA-KIQSSTDYSITAGSKICVVTAGV 677
L Q ++ L+ ++ + +G +DL + +I + DY+ TAGS + VV AG
Sbjct: 27 LIQGNVADVVLLDIVEGRPQGITLDLLEACGVEGHTCRITGTNDYAQTAGSDVLVVAAGF 86
Query: 678 RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRV 857
++ G SR DL+ NT ++ ++ + + +SP+ +V+ ++P+D +++V W+ SGL RV
Sbjct: 87 ARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDAMSHVAWRASGLVPERV 146
Query: 858 IGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+G LD+ARF ++ LG + ++G HG VP+ I+GV L L
Sbjct: 147 MGMAGVLDAARFETFIAWELGFSVRDIRAMVLGGHGDLMVPLPRYTTISGVPLTQL 202
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 103 bits (248), Expect = 7e-21
Identities = 51/172 (29%), Positives = 98/172 (56%), Gaps = 2/172 (1%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSA--FMXNAKIQSSTDYSITAGSKICVVTA 671
+LT + + L+ + +GE+ D +H +A F N +I S DY G+ I V+TA
Sbjct: 19 LLTLGSVSELVLLDQNLERAEGEVFDFRHTAALTFSKNTRIIPSDDYLDLLGADIVVITA 78
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G + ++G++RLD+ + N + +I ++ + +P +L++ S+P DI+ + +G +
Sbjct: 79 GAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNPCDIVAHFITTNTGFEPN 138
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
+VI SG +D+AR ++++R+ + + GY++GEHG S ++IAG
Sbjct: 139 KVISSGCVIDTARLMSIVANRVDLDPKNIFGYVLGEHGSHCFTPKSLISIAG 190
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 103 bits (248), Expect = 7e-21
Identities = 51/169 (30%), Positives = 96/169 (56%), Gaps = 1/169 (0%)
Frame = +3
Query: 522 NIALVXMMANKLKGEMMDL-QHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGES 698
++ L + +G+ +D+ + G + +AK++ + Y+ AG+ +C+VTAGV ++ G S
Sbjct: 29 DVVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGTQSYADIAGADVCIVTAGVPRKPGMS 88
Query: 699 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDL 878
R DL+ N V+K + + +PD ++ ++P+D + + + SGLP ++V G L
Sbjct: 89 RDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLDAMVWALQQFSGLPANKVCGMAGVL 148
Query: 879 DSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
DSARFR+ L++ ++ +++G HG + VP +AG+ L DL
Sbjct: 149 DSARFRHFLAEEFNVSMKDVTAFVLGGHGDTMVPSVRYSTVAGIPLPDL 197
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 103 bits (247), Expect = 1e-20
Identities = 49/174 (28%), Positives = 97/174 (55%), Gaps = 3/174 (1%)
Frame = +3
Query: 513 VTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSST-DYSITAGSKICVVTAGVRQRE 689
+ + L+ + +K GE D H ++ + + I+ DY + I V+TAG R
Sbjct: 28 LATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHLGDYEDCKDANIIVITAGPSIRP 87
Query: 690 GES--RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIG 863
GE+ RL L N ++ ++ +++K + + ++++ ++P+D+ TYV P++ ++G
Sbjct: 88 GETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLDVATYVVSTQFDYPRNLILG 147
Query: 864 SGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+GT L++ RFR +L+D+ + + +GY++GEHG ++ WS AG + DL
Sbjct: 148 TGTMLETYRFRRILADKYQVDPKNINGYVLGEHGNAAFVAWSTTGCAGFPIDDL 201
>UniRef50_Q92AZ3 Cluster: Lin1775 protein; n=13; Listeria|Rep: Lin1775
protein - Listeria innocua
Length = 302
Score = 103 bits (246), Expect = 1e-20
Identities = 54/192 (28%), Positives = 97/192 (50%)
Frame = +3
Query: 447 KVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSST 626
KV I FS++TQ + + I ++ + K + E ++L+ ++ + ++
Sbjct: 4 KVGIIGAGHVGSDVAFSLVTQGICDEIVIIDKIEAKAESEALELRDMASMTRSYTTITAN 63
Query: 627 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVD 806
+ + + I V+ G E R++ + + + +I+P+++ I V ++P D
Sbjct: 64 SWEALSDADIIVMAVGPETLLREDRMEELVETSRSVTEIVPKILATGFKGIFVNITNPCD 123
Query: 807 ILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVW 986
++T + KISG RV G+GT LD+AR R ++ + L I S GY++GEHG S W
Sbjct: 124 VITMLIQKISGFDHSRVFGTGTSLDTARMRRVVGEALHINPKSIEGYVLGEHGESQFVAW 183
Query: 987 SAVNIAGVRLXD 1022
S V I GV + D
Sbjct: 184 STVKIGGVNITD 195
>UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 303
Score = 103 bits (246), Expect = 1e-20
Identities = 59/188 (31%), Positives = 102/188 (54%), Gaps = 3/188 (1%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAK--IQSSTDYSITAGSKICVVTA 671
+ N +++ LV K GE +D+ SA N+K I+ + DYS GS I ++ A
Sbjct: 20 LCVSNGLDDVLLVNTTKEKAIGESLDV--ASAIPANSKFSIRGTDDYSELIGSDIVIIAA 77
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
V + R + + ++K I ++ KY P I+++ S+P+D+LTY K +G +
Sbjct: 78 SVGIYT-KHRAENIDHQVAMIKNIAKKIKKYCPSAIVLLVSNPLDVLTYFFQKTTGFSRF 136
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTS-CHGYIIGEHGXSSVPVWSAVNIAGVRLXDLX 1028
+VIG + LD++RFRY +S+ L + +S + ++GEHG S VP++S V++ L +
Sbjct: 137 KVIGIASSLDTSRFRYYISETLSVPQSSVSNALVLGEHGDSMVPIFSGVSVGDNPLFSMI 196
Query: 1029 NXIGTXXD 1052
+ T D
Sbjct: 197 DSRDTITD 204
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 102 bits (245), Expect = 2e-20
Identities = 47/174 (27%), Positives = 95/174 (54%), Gaps = 1/174 (0%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSA-FMXNAKIQSSTDYSITAGSKICVVTAG 674
++ + + L+ +G +D+Q + F +A++ ST+Y + A S + V+TAG
Sbjct: 22 LVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYELIADSDLVVITAG 81
Query: 675 VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHR 854
++ G SR D++ N ++ I+ +++++P ++++I ++PVD+LTY W+ G + R
Sbjct: 82 KPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVDVLTYHAWRHCGWDRAR 141
Query: 855 VIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
V G LDSAR ++ G++ ++G HG + +P+ I+G+ L
Sbjct: 142 VFGQAGVLDSARMASFIAGETGLSVKDISAMVLGGHGDTMLPLIRYTTISGIPL 195
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 102 bits (244), Expect = 2e-20
Identities = 61/176 (34%), Positives = 96/176 (54%), Gaps = 2/176 (1%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVT 668
F++ + + + L+ K +G+ +DL H +A + N KI SS + + + S + + T
Sbjct: 17 FALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKI-SSGEIADSKDSDVIIFT 75
Query: 669 AGVRQR-EGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLP 845
A V R ++RL++ N +L+ +P L K SP+ I+V+ S+PVD L Y T +++G
Sbjct: 76 ASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVDALAYETIRLTGFD 135
Query: 846 KHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVR 1013
RVIG+GT +DS R+R LLS L I YI+GEHG + S G R
Sbjct: 136 PKRVIGTGTLVDSIRYRALLSTELKIHAQDIRAYILGEHGDTQFAASSIAMTGGER 191
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 102 bits (244), Expect = 2e-20
Identities = 47/149 (31%), Positives = 82/149 (55%), Gaps = 1/149 (0%)
Frame = +3
Query: 519 NNIALVXMMANKLKGEMMDLQH-GSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGE 695
+ IAL+ + + K +DL H S + +I S+D ++ S I V+TAG ++ G+
Sbjct: 27 SQIALIDIFGDLAKARALDLSHLASVYNKKTEISGSSDETLLKNSDIVVITAGKTRQAGQ 86
Query: 696 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTD 875
SR DL+ N ++ + KY+P+ I+++ ++PVD L +V +K SG K ++I +
Sbjct: 87 SRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVDTLAFVAYKASGFKKEKIIAMAGE 146
Query: 876 LDSARFRYLLSDRLGIATTSCHGYIIGEH 962
LDSAR RY ++ + T ++G H
Sbjct: 147 LDSARLRYEIAKSENVNVTDIKASVVGAH 175
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 102 bits (244), Expect = 2e-20
Identities = 49/157 (31%), Positives = 91/157 (57%), Gaps = 1/157 (0%)
Frame = +3
Query: 558 KGEMMDL-QHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVL 734
KG+ +D+ Q +A + ++++ GS + ++TAG + G SR DL+ +N D++
Sbjct: 43 KGKALDMSQAANAARQHTIVKAAKGPEDMEGSDVVIITAGAPRTPGMSRDDLLFKNADIV 102
Query: 735 KQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDR 914
K ++ +Y+PD I+++ S+P+D++TYV K +G P+ RV+G LD+AR + + ++
Sbjct: 103 KCYSREIKEYAPDAIVIVVSNPLDVMTYVALKETGFPRQRVLGMAGILDAARMAHFIYEK 162
Query: 915 LGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
L ++G HG + VP+ +AGV + DL
Sbjct: 163 LEYGAGQIRATVMGGHGDTMVPLPKFTTVAGVPIEDL 199
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 102 bits (244), Expect = 2e-20
Identities = 49/151 (32%), Positives = 86/151 (56%), Gaps = 1/151 (0%)
Frame = +3
Query: 561 GEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLK 737
GE++D+ A + K+++S D GS+I V+TAGV + R DL +N ++
Sbjct: 43 GEVLDMSDALAAKGVSVKLENSADIENVYGSRIVVITAGVPRTADMDRDDLAFKNGRIVA 102
Query: 738 QIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRL 917
Q+ +++PD+I+++ ++PVD++TYV + SG RV G G LDS R + ++
Sbjct: 103 DYARQIARFAPDSIILVVTNPVDVMTYVALRYSGFHPSRVFGLGNHLDSLRLKNYMARHF 162
Query: 918 GIATTSCHGYIIGEHGXSSVPVWSAVNIAGV 1010
+ + H +IG+HG VP+ S+ +I G+
Sbjct: 163 NVHVSEVHTRVIGQHGPYMVPLISSTSIGGI 193
>UniRef50_Q3U1V6 Cluster: Ubiquitin-conjugating enzyme E2 variant 3;
n=23; Tetrapoda|Rep: Ubiquitin-conjugating enzyme E2
variant 3 - Mus musculus (Mouse)
Length = 471
Score = 101 bits (243), Expect = 3e-20
Identities = 49/126 (38%), Positives = 77/126 (61%)
Frame = +3
Query: 612 IQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIA 791
++ S D S +A SK+ + TA ES L VQ N D+ + ++P L YS +L++A
Sbjct: 234 VEISKDLSASAHSKVVIFTAN-SLGGSESYLHAVQSNVDMFRALVPALGHYSQHAVLLVA 292
Query: 792 SDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXS 971
S PV+I++YVTWK+S P RV+G G +LDS R +Y+++ L + T+ +++GE G +
Sbjct: 293 SQPVEIMSYVTWKLSTFPATRVVGIGCNLDSQRLQYIITSVLKVQTSGKEVWVVGEQGEN 352
Query: 972 SVPVWS 989
V WS
Sbjct: 353 KVCSWS 358
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina|Rep:
Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 100 bits (240), Expect = 7e-20
Identities = 52/174 (29%), Positives = 96/174 (55%), Gaps = 6/174 (3%)
Frame = +3
Query: 522 NIALVXMMANKLKGEMMDLQHGSAFMXNA-KIQSSTDYSITAGSKICVVTAGVRQREGES 698
++ L ++ N G+ +DL H +A N ++Q + Y+ G+ + ++TAG+ + G+S
Sbjct: 35 DVVLFDVVPNMPAGKALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKS 94
Query: 699 -----RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIG 863
R DL+ N +L+++ + ++ P ++ ++P+D++ + +GLP RV G
Sbjct: 95 DQEWSRKDLLPVNVKILREVGAAIKQFCPHAFVINITNPLDVMVAALREAAGLPAARVCG 154
Query: 864 SGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
LDSARFR LL+DRLG++ ++G HG + VP+ + GV L +L
Sbjct: 155 MAGVLDSARFRRLLADRLGVSPRDVQAMVLGVHGDNMVPLSRFATVNGVPLGEL 208
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 100 bits (239), Expect = 9e-20
Identities = 48/136 (35%), Positives = 84/136 (61%), Gaps = 4/136 (2%)
Frame = +3
Query: 630 YSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDI 809
Y + A + I ++TAGV ++ G SR+DL++ N +++ + + KY+P ++++ S+P+D
Sbjct: 82 YEVIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDE 141
Query: 810 LTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWS 989
+T +T ++G PK+RV+G LD+ARF + +++ LG+ + +G HG + VPV S
Sbjct: 142 MTALTQLVTGFPKNRVMGQAGMLDTARFSHFVAEELGVPIRAVRTLTLGSHGDTMVPVPS 201
Query: 990 A--VNIAGV--RLXDL 1025
V I G RL DL
Sbjct: 202 QCFVTIDGEQRRLADL 217
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 99 bits (238), Expect = 1e-19
Identities = 48/163 (29%), Positives = 90/163 (55%), Gaps = 1/163 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDL-QHGSAFMXNAKIQSSTDYSITAGSKICVVT 668
+++ + V + IALV + + + + +D+ Q G F D+++ S I VVT
Sbjct: 17 YALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGGDDFALIEASDIVVVT 76
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG ++EG++R DL+ +N V+KQ + K++P+ I++I ++P+D++ + + SG +
Sbjct: 77 AGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVMVWTVLRYSGFDR 136
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSV 977
RVIG +LDSAR RY ++ I+ ++G H +
Sbjct: 137 SRVIGMAGELDSARCRYEIASLKDISAKDVSAKVLGAHNDKMI 179
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor; n=2;
Bacteria|Rep: Lactate/malate dehydrogenase precursor -
Bacillus coagulans 36D1
Length = 327
Score = 99.5 bits (237), Expect = 2e-19
Identities = 53/176 (30%), Positives = 97/176 (55%), Gaps = 7/176 (3%)
Frame = +3
Query: 519 NNIALVXMMANKLKGEMMDLQHGSA--FMXNAKIQSSTDYSITAGSKICVVTAGV----- 677
+ IA++ GE +D +H +A +M N +++ DYS A + + + AG
Sbjct: 29 SEIAVLDKKKGVAFGEALDWRHATALTYMPNTSVKAG-DYSECADADVIICAAGPSVLPS 87
Query: 678 RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRV 857
+ E R L + N V+++++ + KY+ + +++ ++P+D + Y+ G K R+
Sbjct: 88 EKDEMPDRAGLARTNAAVVREVMAGITKYTKEAVIIFITNPLDTIVYIAENEFGYSKGRI 147
Query: 858 IGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
G+GT LDSAR R L+++ I S GY++GEHG ++ PV+S +N+ G R +L
Sbjct: 148 FGTGTMLDSARLRQLVAENYSIDPKSVTGYMMGEHGFTAFPVFSRLNVQGFREKEL 203
>UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene encodes
predicted malate dehydrogenase; n=8; Cryptosporidium|Rep:
Lactate dehydrogenase, adjacent gene encodes predicted
malate dehydrogenase - Cryptosporidium parvum Iowa II
Length = 337
Score = 99.5 bits (237), Expect = 2e-19
Identities = 47/154 (30%), Positives = 86/154 (55%), Gaps = 1/154 (0%)
Frame = +3
Query: 558 KGEMMDLQHGSA-FMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVL 734
+G+ +D+ H F +K+ + DY+ +GS + ++TA + R + R +L+ N +L
Sbjct: 58 QGKALDITHSMVMFGSTSKVIGTNDYADISGSDVVIITASIPGRPKDDRSELLFGNARIL 117
Query: 735 KQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDR 914
+ + KY P+ ++ ++P+D++ K+SGLP ++V G LDS+RFR ++
Sbjct: 118 DSVAEGVKKYCPNAFVICITNPLDVMVSHFQKVSGLPHNKVCGMAGVLDSSRFRTFIAQH 177
Query: 915 LGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
G+ + +IG HG VPV S+V++ GV L
Sbjct: 178 FGVNASDVSANVIGGHGDGMVPVTSSVSVGGVPL 211
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 99.5 bits (237), Expect = 2e-19
Identities = 49/185 (26%), Positives = 98/185 (52%), Gaps = 6/185 (3%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTA 671
+++ Q ++ L ++ N G+ +D H + N K+ S Y AG+ + +VTA
Sbjct: 21 TLIVQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGADVVIVTA 80
Query: 672 GVRQREGES-----RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKIS 836
G + G+S R DL+ N ++ +I + K P+ +++ ++PVD++ + + S
Sbjct: 81 GFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPVDVMVQLLHQHS 140
Query: 837 GLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
G+PK+++IG G LD++R +Y +S +L + + +I+G HG V + + + G+ L
Sbjct: 141 GVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNAHIVGAHGNKMVLLKRYITVGGIPL 200
Query: 1017 XDLXN 1031
+ N
Sbjct: 201 QEFIN 205
>UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5;
Methanococcus|Rep: Malate dehydrogenase - Methanococcus
maripaludis
Length = 314
Score = 99.1 bits (236), Expect = 2e-19
Identities = 58/162 (35%), Positives = 86/162 (53%), Gaps = 3/162 (1%)
Frame = +3
Query: 549 NKLKGEMMDLQHGSAFMX---NAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQR 719
NKLKG MDL A + I D S TA S I ++TAG+ + SR+DL++
Sbjct: 39 NKLKGLKMDLYDAMAAAGQDTDIDICCDDDLSCTANSDITIITAGMARTGEMSRIDLMKG 98
Query: 720 NTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRY 899
N ++K + + + DT + + S+PVD++TY SG K++V G GT LDS RF+
Sbjct: 99 NAKIVKNYVKNIANFG-DTKIFMISNPVDLMTYKALIESGYEKNQVFGLGTHLDSMRFKV 157
Query: 900 LLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
++ + I+GEHG S VPV SA + G+ + L
Sbjct: 158 AVAKHFEVHLDDVRTRIVGEHGDSMVPVISATAVGGIPIKRL 199
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 98.7 bits (235), Expect = 3e-19
Identities = 52/167 (31%), Positives = 91/167 (54%), Gaps = 1/167 (0%)
Frame = +3
Query: 525 IALVXMMANKLKGEMMDLQHGSA-FMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESR 701
+ LV + KG M D++H +A F + ++++ D S + V+TAG ++ SR
Sbjct: 33 MVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAYDDVSKVENADAIVITAGKPRKADMSR 92
Query: 702 LDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLD 881
DL + N +++ I +L +P ++ ++PVD++T + + G K VIG+GT LD
Sbjct: 93 RDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTMILSDVIG-NKGTVIGTGTSLD 151
Query: 882 SARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
+ RFR +S+ L + GY++GEHG + WS V + GV + +
Sbjct: 152 TYRFRSAVSELLNEPIAAIDGYVVGEHGEEAFVAWSTVTVKGVPIDE 198
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 98.7 bits (235), Expect = 3e-19
Identities = 52/172 (30%), Positives = 92/172 (53%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++ + Q + + ++ + + G D + SA + S +Y + V+TA
Sbjct: 20 YAAMNQGLASEYGIIDINPDFADGNAFDFEDASASLPFPISVSRYEYKDLKDADFIVITA 79
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
G Q+ GE+RL+LV N ++++I ++ + I +I ++PVDI+T SG
Sbjct: 80 GRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVDIITRAYRDASGFSDQ 139
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
+VIGSGT LD+AR ++ ++ R ++ S Y++GEHG SS +S + IAG
Sbjct: 140 KVIGSGTVLDTARLQFAIAKRAKVSPNSVQAYVMGEHGDSSFVAYSNIKIAG 191
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 96.7 bits (230), Expect = 1e-18
Identities = 46/185 (24%), Positives = 97/185 (52%), Gaps = 6/185 (3%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTA 671
+++ Q ++ + ++ N +G+ +D H + N K+ S Y G+ + +VTA
Sbjct: 14 TLIVQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDLKGADVVIVTA 73
Query: 672 GVRQREGES-----RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKIS 836
G + G+S R DL+ N ++ +I + P+ +++ ++PVD++ + ++ S
Sbjct: 74 GFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQLLFEHS 133
Query: 837 GLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
G+PK+++IG G LD++R +Y +S +L + + I+G HG V + + + G+ L
Sbjct: 134 GVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIVGAHGNKMVLLKRYITVGGIPL 193
Query: 1017 XDLXN 1031
+ N
Sbjct: 194 QEFIN 198
>UniRef50_A3ZZ88 Cluster: L-lactate/malate dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep: L-lactate/malate
dehydrogenase - Blastopirellula marina DSM 3645
Length = 308
Score = 95.5 bits (227), Expect = 3e-18
Identities = 51/173 (29%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA-KIQSSTDYSITAGSKICVVTA 671
+++ + + + + LV + E DL H + ++ ++++ D TAGS + +
Sbjct: 18 AIVLKGLADELVLVSRRTEMARSEADDLNHAAGLEEHSVEVRAGGDVD-TAGSDVILYCD 76
Query: 672 GVRQREGE-SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
+ + + R + N + L++ IP L SP I V+ ++PVD++T+ ++SG P+
Sbjct: 77 AAQSKTSDVDRYCAARGNLERLRERIPILAAASPQAICVMVTNPVDVMTWFALQLSGFPQ 136
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
RV G GT LD+AR R LLS+R + + Y+IGEHG V +S+ ++ G
Sbjct: 137 ERVFGVGTLLDTARLRRLLSERWSVHASDVRAYVIGEHGEDQVASFSSASLGG 189
>UniRef50_Q1FMY2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
phytofermentans ISDg|Rep: L-lactate dehydrogenase -
Clostridium phytofermentans ISDg
Length = 319
Score = 94.7 bits (225), Expect = 5e-18
Identities = 49/195 (25%), Positives = 97/195 (49%), Gaps = 2/195 (1%)
Frame = +3
Query: 447 KVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSST 626
KV I +++ Q + I + + K K + +D+ + ++ + S
Sbjct: 6 KVIIIGAGHVGSHAGYALAEQGLAEEIIFIDIDREKAKAQALDIYDATVYLPHRVKVKSG 65
Query: 627 DYSITAGSKICVVTAGVR--QREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDP 800
DYS A + + V+ G + +GE+R+ + ++K++ + D ++V S+P
Sbjct: 66 DYSDAADADLMVIAVGTNPDKNKGETRMSTLTNTALIIKEVAWHIKNSGFDGMIVSISNP 125
Query: 801 VDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVP 980
D++T+ + +++I + T LDSAR R ++D + I S +G+++GEHG S +
Sbjct: 126 ADVITHYLQHLLQYSSNKIISTSTVLDSARLRRAIADAVEIDQKSIYGFVLGEHGESQMV 185
Query: 981 VWSAVNIAGVRLXDL 1025
WS V+IAG + +L
Sbjct: 186 AWSTVSIAGKPILEL 200
>UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=3;
Lactobacillales|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 304
Score = 94.3 bits (224), Expect = 6e-18
Identities = 51/178 (28%), Positives = 91/178 (51%), Gaps = 2/178 (1%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXN-AKIQSSTDYSITAGSKICVVTAG 674
++ Q + + I LV KL E +D + ++ + + ++ + T +T +
Sbjct: 20 IIAQGLADEIVLVDKNPEKLASEELDFRDAASLLDHHVEVHAGTVTDLTDAEVVISALGH 79
Query: 675 VRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
+ + G R ++ NT ++Q+ L + + +L++ S+PVD++T + K +GLP +
Sbjct: 80 IELIKPGGDRFTELKANTPEVQQVGSDLKQAGFNGVLIVISNPVDVITGIYQKATGLPAN 139
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+V G+GT LD+AR + L D L I GY++GEHG S WS VN G +L
Sbjct: 140 QVFGTGTYLDTARLKRALGDTLAIDPRGISGYMLGEHGDSQFAAWSTVNALGKNADEL 197
>UniRef50_Q6YPG1 Cluster: Putative uncharacterized protein
OJA1212_C06.24; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OJA1212_C06.24 - Oryza sativa subsp. japonica (Rice)
Length = 255
Score = 93.1 bits (221), Expect = 1e-17
Identities = 57/129 (44%), Positives = 69/129 (53%)
Frame = -1
Query: 910 SDSR*RNRAESKSVPDPMTRCLGSPLIFHVTYVRISTGSLAITNIVSGLYFISCGIICLS 731
S R RN ES+ VP+PMTR G+P FH TYV STG I++ SG S G I +
Sbjct: 47 SARRKRNLEESRLVPEPMTRLAGNPDSFHATYVSTSTGLETISSSASGECSASAGTIFRN 106
Query: 730 TSVFLCTRSRRDSPSRCRTPAVTTQIFEPAVIE*SVLDWILAFXMNADPCCRSIISPFNL 551
++ F C+R RR SP R PAVT EP V SV + NA CCRS ISP +L
Sbjct: 107 SATFRCSRFRRLSPGIWRAPAVTMARSEPRVTARSVSETRRTRGRNAAACCRSSISPRSL 166
Query: 550 LAIMXTRAM 524
T A+
Sbjct: 167 SGTASTSAI 175
>UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=2;
Oenococcus oeni|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 304
Score = 91.9 bits (218), Expect = 3e-17
Identities = 53/170 (31%), Positives = 89/170 (52%), Gaps = 2/170 (1%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV 677
++ + + + I L+ + LK E +D +F+ + + DY A + + V T G
Sbjct: 20 VIDRGMVDEIVLLDINQKHLKAEALDFWDAQSFLPHHTKIIAGDYKDLADANLIVSTFGN 79
Query: 678 RQREGES--RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
ES R +Q N ++ + QL K D + + ++PVD++T V + LPK+
Sbjct: 80 VNLTVESGDRFAELQFNVKQIRSMAEQLKKVHFDGVFLTITNPVDVITAVYQRELALPKN 139
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNI 1001
+VIG+GT LDS+R + + +R I S G++IGEHG S P WS++ I
Sbjct: 140 QVIGTGTFLDSSRLKKEIGERFKIDPRSVSGFVIGEHGNSQFPAWSSIRI 189
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 91.5 bits (217), Expect = 4e-17
Identities = 49/161 (30%), Positives = 91/161 (56%), Gaps = 1/161 (0%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGS-AFMXNAKIQS 620
S++ I ++++ ++ + + LV A G++ DL + A ++ S
Sbjct: 8 SRIAIVGVGQVGAAAAYALVLGSIADELLLVDTRAAWRDGQVRDLSDAAYASRSKTRVYS 67
Query: 621 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDP 800
+T Y + I V+TAG + G++ +D + RNT +++ II ++ + DT+L+I ++P
Sbjct: 68 AT-YREASQCDIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANP 126
Query: 801 VDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGI 923
VD++T + ++S LP +V+GSGT LDS R R LL+D G+
Sbjct: 127 VDLMTSLAKELSNLPSAQVLGSGTFLDSIRLRGLLADETGV 167
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 90.6 bits (215), Expect = 7e-17
Identities = 51/179 (28%), Positives = 93/179 (51%), Gaps = 1/179 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHG-SAFMXNAKIQSSTDYSITAGSKICVVT 668
F + TQ + I + + + +G +D+ H SA + ++ + + S G + V
Sbjct: 15 FILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVANEPSDLRGCDVVVFC 74
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG ++ G SR DL+ N V++ ++ ++ Y +++LV+ S+P+D + Y K SGL
Sbjct: 75 AGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAMVYTAIKESGLSP 134
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+V+G LDSAR + ++LG + ++G HG VP+ N+AGV + +L
Sbjct: 135 LQVLGMAGILDSARMASFIFEKLGYGSDQIVASVMGGHGDDMVPLPRYSNVAGVPITEL 193
>UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 325
Score = 89.0 bits (211), Expect = 2e-16
Identities = 55/179 (30%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTD-YSITAGSKICVVT 668
S+L Q + + + L + K+ E+ DL+ +F+ N KI + D Y A + V
Sbjct: 22 SLLMQGIADELYLCDINEAKVTSEVQDLRDSLSFVPYNTKIVNCYDHYEELACCDVIVNA 81
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG +R + TD + +++ D I V S+P D++ W ++G
Sbjct: 82 AGKVALAAGNRDGELFFTTDAARSFAKRIVDAGFDGIFVSISNPCDVVCTELWHLTGYDP 141
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
++IGSG LDSAR R +S ++G++ S Y+IGEHG S + + A IAG L +L
Sbjct: 142 KKIIGSGCGLDSARLRTEISKKVGVSPKSVDAYMIGEHGFSQLAAFKAATIAGKSLNEL 200
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 87.8 bits (208), Expect = 5e-16
Identities = 38/129 (29%), Positives = 74/129 (57%)
Frame = +3
Query: 624 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPV 803
T T G + A + E +R DLV N+ +++ + + KY+P+ +++ ++P+
Sbjct: 118 TAMECTMGKGARLAKAPTKSNEEWNRDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPM 177
Query: 804 DILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
D++ ++ K++G PK+ V+G G LDS+R ++++LG+ HG +IG HG S +P+
Sbjct: 178 DVMVHLMLKVTGFPKNMVVGMGGLLDSSRMNCYIAEKLGVNPKYVHGSVIGAHGDSMIPL 237
Query: 984 WSAVNIAGV 1010
S + G+
Sbjct: 238 VSRSTVYGI 246
Score = 34.7 bits (76), Expect = 5.2
Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
Frame = +3
Query: 561 GEMMDLQHGSAFMXNA-KIQSSTDYSITAGSKICVVTAGVRQREGES 698
G+ +D+ H ++ A K + + +Y +GS +C+VTAG E S
Sbjct: 46 GKSLDIMHANSIQGKAYKCKGTNNYEDISGSDVCIVTAGNSYEENNS 92
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 87.4 bits (207), Expect = 7e-16
Identities = 45/156 (28%), Positives = 84/156 (53%), Gaps = 1/156 (0%)
Frame = +3
Query: 558 KGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVL 734
+G+ +DL+H S + N I + + I V+TAGV+++EG +R DL+ N ++
Sbjct: 39 QGKALDLKHFSTILGVNRNILGTNQIEDIKDADIIVITAGVQRKEGMTREDLIGVNGKIM 98
Query: 735 KQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDR 914
K + + + ++ S+P+DI+ V K S LP ++ G LD++R+ L++D+
Sbjct: 99 KSVAESVKLHCSKAFVICVSNPLDIMVNVFHKFSNLPHEKICGMAGILDTSRYCSLIADK 158
Query: 915 LGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
L ++ + I+G HG VP+ ++ GV L +
Sbjct: 159 LKVSAEDVNAVILGGHGDLMVPLQRYTSVNGVPLSE 194
>UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 321
Score = 86.2 bits (204), Expect = 2e-15
Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 8/170 (4%)
Frame = +3
Query: 525 IALVXMMANKLKGEMMDLQHGSAF--MXNAKIQSSTDYSITAGSKICVVTAGVR------ 680
I ++ + G+ +D H +A + N + + DY + + + ++TAG
Sbjct: 33 ICVIDVNEKLAAGQALDQHHATALPNVTNVAVYAG-DYDDLSNADVIIMTAGPSIDASNG 91
Query: 681 QREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVI 860
G +R +L N +++ + Q+ + D ++I S+P+D L ++ P+ V+
Sbjct: 92 PATGAARRELAATNGKIIRSTMTQITSRNHDAAIIICSNPLDALVHIASTEFDHPQGLVL 151
Query: 861 GSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGV 1010
G+GT LDSAR +++D LG+ GY+IGEHG S P+++ VN+ GV
Sbjct: 152 GTGTILDSARMCRVVADHLGVDPDYVRGYMIGEHGPSGFPMFTGVNVGGV 201
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 85.8 bits (203), Expect = 2e-15
Identities = 47/169 (27%), Positives = 92/169 (54%), Gaps = 2/169 (1%)
Frame = +3
Query: 495 SMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA-KIQSSTDYSITAGSKICVVTA 671
S++ + + + LV + ++ ++ DL + + KI+++T + + + + ++TA
Sbjct: 19 SLIHRRIQGTLLLVDIKSSLRDAQVRDLADAALVYGSVTKIEAAT-HQEASQADVVIITA 77
Query: 672 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
GV GE+ L + +LK I+ ++ ++P+ I+++ ++PVD LT + I+GLP+
Sbjct: 78 GVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTLAQDIAGLPRK 137
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIG-EHGXSSVPVWSAV 995
+VIG GT +DS R + +S LG GY++G S V WS +
Sbjct: 138 QVIGVGTCIDSLRLQDEVSRFLGTTMEETEGYVVGVRDSESQVVGWSGL 186
>UniRef50_Q38YI2 Cluster: Putative malate dehydrogenase; n=1;
Lactobacillus sakei subsp. sakei 23K|Rep: Putative malate
dehydrogenase - Lactobacillus sakei subsp. sakei (strain
23K)
Length = 301
Score = 83.8 bits (198), Expect = 9e-15
Identities = 49/190 (25%), Positives = 88/190 (46%), Gaps = 2/190 (1%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSS 623
+KV I ++++++ + + + L + E DL+ G ++
Sbjct: 2 NKVAIIGIGHVGSTVAYTLVSRRICSELVLFDQKPKLAEAERNDLEAGQVDHTGFVKITA 61
Query: 624 TDYSITAGSKICVVTAGVRQ--REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASD 797
D S A + + +AG + R D + + Q P+L + IL+ ++
Sbjct: 62 NDESQLATCDLVIFSAGDISILEHSDDRFDELTYTKTAVAQWAPKLKAANFKGILLNITN 121
Query: 798 PVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSV 977
P D++T ++G PK RV+G+GT LD+AR + + L +A S GY++GEHG S
Sbjct: 122 PCDVITQYLQALTGFPKERVLGTGTTLDTARMQVAVGHYLNVAPNSVQGYVLGEHGNSQF 181
Query: 978 PVWSAVNIAG 1007
WS V++ G
Sbjct: 182 VAWSGVHVGG 191
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 82.6 bits (195), Expect = 2e-14
Identities = 45/181 (24%), Positives = 93/181 (51%), Gaps = 1/181 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDL-QHGSAFMXNAKIQSSTDYSITAGSKICVVT 668
++++ + + N I LV + + L + ++L Q +A N + + DY+ T S I + +
Sbjct: 17 YALILREIANEIVLVDINEDLLYAKELELTQSIAALNLNIDLLCTKDYTHTKNSDIVLFS 76
Query: 669 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
AG +++G+SR +L+Q NT ++ ++ ++ D + +I ++PVD L ++
Sbjct: 77 AGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVDFLLNTLYESGIFSS 136
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLX 1028
++I LD+ARF+Y L+ +L + + +IG H V V S ++ + +
Sbjct: 137 KKIIAMAGVLDNARFKYELAKKLNVKMSRVDTRLIGFHNDDMVLVKSYASVKNKNISEFL 196
Query: 1029 N 1031
N
Sbjct: 197 N 197
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 82.6 bits (195), Expect = 2e-14
Identities = 48/183 (26%), Positives = 88/183 (48%), Gaps = 7/183 (3%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMX-NAKIQSSTDYSITAGSKICVVTAG 674
+L Q V + LV N G + DL+ + N + Y + + +TA
Sbjct: 20 LLQQGVQADYLLVDKNTNLADGHVRDLRDSKSLKSHNGSTFNVGTYDDLKDADVVAITAS 79
Query: 675 ---VRQREGE---SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKIS 836
V +GE RL L+ N +L +I +L + + +I ++P D++ V K++
Sbjct: 80 IPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGLSIIPTNPCDVMAGVYQKVT 139
Query: 837 GLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
G H++I +G L++ R R ++S+ LG+ + S G+++GEHG ++ WS + V +
Sbjct: 140 GFDPHKIISTGCQLETMRTRKMISEALGVNSDSVEGFVVGEHGSGAIVPWSVFRVGNVPM 199
Query: 1017 XDL 1025
L
Sbjct: 200 KQL 202
>UniRef50_Q88ZG9 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=2;
Lactobacillus plantarum|Rep: L-2-hydroxyisocaproate
dehydrogenase - Lactobacillus plantarum
Length = 319
Score = 81.4 bits (192), Expect = 5e-14
Identities = 43/181 (23%), Positives = 88/181 (48%), Gaps = 3/181 (1%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
++++ + + + + L+ A K + E +DLQ A + + I DY + I VT+
Sbjct: 18 YTLVCKGIADELVLIDTNAAKARAEQLDLQDAQARLDSRTIIKINDYHELDDTDILFVTS 77
Query: 672 G---VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGL 842
G +R + +++ I P++ + +++ +P D +T+ + +GL
Sbjct: 78 GNIHALDHASGNRWAEFEYTKQIVQDIAPKVKATKFNGVVIDTMNPCDAITHYFQRATGL 137
Query: 843 PKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXD 1022
+ +V G+GT LD+AR + ++++ + GY+ GEHG S WS V + G+ +
Sbjct: 138 SRQQVFGTGTFLDTARMQKVVAEAFDCDPKNISGYVYGEHGESQFSAWSTVQVNGIPITS 197
Query: 1023 L 1025
L
Sbjct: 198 L 198
>UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=3;
Streptococcus thermophilus|Rep: L-2-hydroxyisocaproate
dehydrogenase - Streptococcus thermophilus (strain CNRZ
1066)
Length = 316
Score = 81.4 bits (192), Expect = 5e-14
Identities = 46/172 (26%), Positives = 82/172 (47%), Gaps = 3/172 (1%)
Frame = +3
Query: 501 LTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAG-- 674
+ Q + ++ + + K++ + D + A + N DY + + + G
Sbjct: 22 IAQGLADSYVFIDINERKVEADAQDFKDAMANLANYANIVVNDYEALKDADVIISALGNI 81
Query: 675 -VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKH 851
++ GE R + + Q+ +L + IL++ S+PVD +T + + +G PK
Sbjct: 82 QLQHNAGEDRFAEFPFTREAVYQVAQELKQLDFKGILLVISNPVDAVTALYQEFTGWPKE 141
Query: 852 RVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
RVIG+GT LD+AR + + + L + S GY +GEHG S WS V + G
Sbjct: 142 RVIGTGTLLDTARMKTAVGEVLEVNPKSVSGYNLGEHGNSQFTAWSQVKVKG 193
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 80.2 bits (189), Expect = 1e-13
Identities = 44/154 (28%), Positives = 81/154 (52%), Gaps = 1/154 (0%)
Frame = +3
Query: 519 NNIALVXMMANKLKGEMMDLQHGSA-FMXNAKIQSSTDYSITAGSKICVVTAGVRQREGE 695
+ +ALV ++ G +D+ HG+ + + ++ S D AG++ V+TAG ++ G
Sbjct: 149 SEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGSDDLVALAGAEYIVITAGKPRQPGM 208
Query: 696 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTD 875
SR DL N +++ + + ++P++ LVI S+P++ +T++ + +G P+ RV+G
Sbjct: 209 SRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPLEEMTHLAAQQTGFPEERVLGMAGV 268
Query: 876 LDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSV 977
LDSARF L+ +G HG V
Sbjct: 269 LDSARFCALVGLTGKARPQEVRAVALGSHGPEMV 302
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 78.6 bits (185), Expect = 3e-13
Identities = 44/160 (27%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +3
Query: 507 QNVTNNIALVXMMANKLKGEMMDLQHGSA-FMXNAKIQSSTDYSITAGSKICVVTAGVRQ 683
+++ I L + KG +D+ +A F I+ Y A S++ ++TAG +
Sbjct: 25 RHIAKEILLFSNDIPRCKGVGLDISQAAAIFDIPILIKGCNSYEEIAESEVVIITAGFPR 84
Query: 684 REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIG 863
+R DL+ +N ++++I + + +P ++L++ S+P+D + V + S K RVIG
Sbjct: 85 TPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDAMCLVAKQWSKFEKERVIG 144
Query: 864 SGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPV 983
LDSAR Y LG Y+IG H +P+
Sbjct: 145 MAGILDSARLTYESKVMLGDFNKHIQSYVIGSHSDDMLPL 184
>UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=15;
Lactobacillales|Rep: L-2-hydroxyisocaproate dehydrogenase
- Lactobacillus confusus
Length = 310
Score = 78.6 bits (185), Expect = 3e-13
Identities = 44/174 (25%), Positives = 87/174 (50%), Gaps = 4/174 (2%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV 677
++ Q V ++ + K+K + +D Q A + D++ A + + + T G
Sbjct: 21 LIAQGVADDYVFIDANEAKVKADQIDFQDAMANLEAHGNIVINDWAALADADVVISTLGN 80
Query: 678 RQREGES----RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLP 845
+ + ++ R ++ + +++ + L + +LV+ S+PVD++T + ++G P
Sbjct: 81 IKLQQDNPTGDRFAELKFTSSMVQSVGTNLKESGFHGVLVVISNPVDVITALFQHVTGFP 140
Query: 846 KHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
H+VIG+GT LD+AR + + + + S GY +GEHG S WS V + G
Sbjct: 141 AHKVIGTGTLLDTARMQRAVGEAFDLDPRSVSGYNLGEHGNSQFVAWSTVRVMG 194
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 77.8 bits (183), Expect = 6e-13
Identities = 33/107 (30%), Positives = 62/107 (57%)
Frame = +3
Query: 705 DLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDS 884
DL+ N V K++ + +++PD +++ ++P+D + Y K+SGLP R+IG LD+
Sbjct: 17 DLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIVYAFHKLSGLPAERIIGMAGALDT 76
Query: 885 ARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
ARFR ++ G++ ++G HG + +PV ++ G+ L +L
Sbjct: 77 ARFRTYIAMETGLSVKDVSCLVMGGHGPTMIPVTRTASVGGIPLTEL 123
>UniRef50_Q6ABQ3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 322
Score = 76.6 bits (180), Expect = 1e-12
Identities = 34/116 (29%), Positives = 68/116 (58%)
Frame = +3
Query: 693 ESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGT 872
+SR L Q N+ V+++++ + +Y+ +++ ++P+D+ ++ P + V+G+GT
Sbjct: 95 DSRNSLAQVNSKVIREVMGNICQYTHSAPIILITNPLDVNVHIAATEFDYPTNLVVGTGT 154
Query: 873 DLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXNXIG 1040
LDSAR R L+D G++ S +++GEHG ++ P S +I G+ L + +G
Sbjct: 155 ALDSARLRRHLADWAGVSPDSVQAFMLGEHGATAFPYLSHASIGGLTLAEATTALG 210
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 76.2 bits (179), Expect = 2e-12
Identities = 40/146 (27%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = +3
Query: 573 DLQHG-SAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIP 749
+++H +A ++ S+ + +G+ I V+TAG ++ G SR DL N ++ +
Sbjct: 45 EIRHALAALRVKTELLSTNNIDDISGADIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAK 104
Query: 750 QLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIAT 929
+L K + + ++ ++PVD++ V K SG I +G +++ R R ++ +L I
Sbjct: 105 KLPKKNKGAMYIMVANPVDMMASVFMKYSG---ENTISTGNQVETMRMRSYIAKKLNIPA 161
Query: 930 TSCHGYIIGEHGXSSVPVWSAVNIAG 1007
GY+ GEHG +++ +WS V + G
Sbjct: 162 YEVGGYVGGEHGEAAMVLWSTVTVKG 187
>UniRef50_Q2FPC3 Cluster: Lactate/malate dehydrogenase; n=2;
Methanomicrobiales|Rep: Lactate/malate dehydrogenase -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 290
Score = 75.4 bits (177), Expect = 3e-12
Identities = 48/168 (28%), Positives = 84/168 (50%), Gaps = 1/168 (0%)
Frame = +3
Query: 501 LTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV- 677
++ + N++ L L+ + +D++H + +S I + AG+
Sbjct: 21 VSSGLINHLVLYDCNQALLEAQRLDIEH-----MRCPVTTSIRPEDIVACDIILYAAGLP 75
Query: 678 RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRV 857
R + ++R L+ N V ++ + Y I+++ ++P DILTY WK G+ K+R+
Sbjct: 76 RNQNIKTRAALLDCNVPVASELATLIPDYKG--IIIVVTNPADILTYYLWKSLGILKNRI 133
Query: 858 IGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNI 1001
IG G LDSARF+Y LS + + G I+GEHG VP++S +
Sbjct: 134 IGFGGQLDSARFQYELS----LRSIRDDGIILGEHGEHQVPIFSKTGL 177
>UniRef50_Q0P989 Cluster: L-lactate dehydrogenase; n=10;
Campylobacter|Rep: L-lactate dehydrogenase -
Campylobacter jejuni
Length = 308
Score = 73.7 bits (173), Expect = 9e-12
Identities = 55/195 (28%), Positives = 90/195 (46%), Gaps = 2/195 (1%)
Frame = +3
Query: 444 SKVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXN-AKIQS 620
+K+ I +S++ Q + + + L + + DL+ SA + KI
Sbjct: 2 AKIGIVGLGYVGAASAYSIVIQGICSELYLYDIKQDLALAHARDLEDMSAIHFSYTKIFH 61
Query: 621 STDYSITAGSKICVVTAGVRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASD 797
+ A I ++ +E SRL ++ N LK I+ L + ++A++
Sbjct: 62 VPNLENLASCDIIILAFRKESLKELPSRLVELKNNILELKDIVLTLKNANFKGKYIVATN 121
Query: 798 PVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSV 977
P D +TY T +S LPK+ V GSGT+LDS+R + LL+ L I + +IGEHG S
Sbjct: 122 PNDTITYYTQVLSQLPKNHVFGSGTNLDSSRLKKLLAKDLNINSKDIFACMIGEHGDSQF 181
Query: 978 PVWSAVNIAGVRLXD 1022
S ++ G L D
Sbjct: 182 AALSNASVLGQNLLD 196
>UniRef50_Q034P5 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: Enzyme with possible
activities of L-2- hydroxyisocaproate/malate/lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 301
Score = 73.3 bits (172), Expect = 1e-11
Identities = 42/171 (24%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Frame = +3
Query: 492 FSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTA 671
F+++++ V + + L+ A +GE DL+ + DY + + +
Sbjct: 19 FNLVSKGVADKLVLIDKKAELAEGESFDLKDALGGLPTYTDIVVNDYDALKDADVVISAV 78
Query: 672 G-VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPK 848
G + R+ + + L + P+L +L+ ++P D +T + LPK
Sbjct: 79 GNIGAISNGDRIGETKTSKVALDDVAPKLKASGFHGVLLDITNPCDAVTSYWQYLLDLPK 138
Query: 849 HRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNI 1001
++IG+GT LD+ R R ++D L + GY +GEHG S WS V +
Sbjct: 139 SQIIGTGTSLDTYRMRRAVADTLHVNVADVRGYNMGEHGESQFTAWSTVRV 189
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 72.5 bits (170), Expect = 2e-11
Identities = 47/182 (25%), Positives = 85/182 (46%), Gaps = 7/182 (3%)
Frame = +3
Query: 498 MLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNA-KIQSSTDYSITAGSKICVVTAG 674
M+ + ++ L + KG +D+ H + I + + + S + VVT
Sbjct: 24 MICEKNLGDVVLHDFRKDLPKGRALDILHTRPLNRSRINILGTNEITDIKDSLVVVVTIE 83
Query: 675 VRQRE----GESRLD--LVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKIS 836
V +RE E L+ + N +LK++ L K+ P +V+ + PVD + V + +
Sbjct: 84 VSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSPVDCMAKVLQEHA 143
Query: 837 GLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRL 1016
+P H++ G L SAR R+ L+++L + G++IG HG VP+ + G+ L
Sbjct: 144 NIPPHKICGMAGVLHSARLRHNLAEKLRVNPGDVQGFVIGAHGDKMVPLPRYCCVNGIPL 203
Query: 1017 XD 1022
D
Sbjct: 204 SD 205
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 70.9 bits (166), Expect = 6e-11
Identities = 47/146 (32%), Positives = 81/146 (55%), Gaps = 1/146 (0%)
Frame = +3
Query: 555 LKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV-RQREGESRLDLVQRNTDV 731
L+ +++DLQH + ST+ + + I V AG R + ++R DL++ N V
Sbjct: 39 LRAQVLDLQH-----TGIDVAISTETAAMRDADIFVFAAGTPRTPDIKTRADLLEANIPV 93
Query: 732 LKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSD 911
K+ +L++ P ++ + ++P+D Y WK+ G+ + R IG G+ LDSARF L +
Sbjct: 94 AKRC-SELLEGFPGVVISV-TNPMDANNYGLWKMMGIDRRRCIGFGSQLDSARFAGFLRE 151
Query: 912 RLGIATTSCHGYIIGEHGXSSVPVWS 989
+GI + +++GEHG VPV+S
Sbjct: 152 -VGIPGPA---WVLGEHGDRQVPVFS 173
>UniRef50_Q82R06 Cluster: Putative lactate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative lactate
dehydrogenase - Streptomyces avermitilis
Length = 303
Score = 70.1 bits (164), Expect = 1e-10
Identities = 41/118 (34%), Positives = 66/118 (55%)
Frame = +3
Query: 654 ICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKI 833
+ V A R + R+ N V++ + L Y T+LV+ ++PVD++T + +
Sbjct: 75 VAVRAAFTNTRAADVRMGGALTNAPVIRALATTLRGYQ-GTVLVV-TNPVDLMTRLFAET 132
Query: 834 SGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
SG P RV G G++LDSAR+R L+ L + T+ HG++IGEHG +V S+ + G
Sbjct: 133 SGCP--RVYGIGSNLDSARYRLTLAHLLDVPATTVHGHVIGEHGDGAVVCASSTTVNG 188
>UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH -
Lactobacillus acidophilus
Length = 304
Score = 66.9 bits (156), Expect = 1e-09
Identities = 45/189 (23%), Positives = 89/189 (47%), Gaps = 4/189 (2%)
Frame = +3
Query: 447 KVXIXXXXXXXXXXXFSMLTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQ-SS 623
KV I +++ T + + + L+ +K+ E DL+ S N ++ +
Sbjct: 3 KVGIIGMGHVGATVAYTLFTHGIADELVLIDKNEDKVAAEYNDLRD-SLSRNNYYVRVTM 61
Query: 624 TDYSITAGSKICVVTAG---VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 794
D+ + I V G + G+ R + N K++ ++ +L+ S
Sbjct: 62 QDWHELKDADIIVTAFGDIAASVKTGD-RFGEFELNAKNAKEVGEKIKNTGFKGVLLNIS 120
Query: 795 DPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSS 974
+P D + + + +GL K++V+G+GT LD+AR + ++ ++LG + G+++GEHG S
Sbjct: 121 NPCDAVAQILQETTGLSKNQVLGTGTFLDTARMQRIIGEKLGQDPKNVEGWVLGEHGSSQ 180
Query: 975 VPVWSAVNI 1001
WS V +
Sbjct: 181 FIAWSTVRV 189
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 64.5 bits (150), Expect = 6e-09
Identities = 41/174 (23%), Positives = 84/174 (48%), Gaps = 3/174 (1%)
Frame = +3
Query: 513 VTNNIALVXMMANKLKGEMMDL--QHGSAFMXNAKIQSSTDYSITAGSKICVVTAGV-RQ 683
V N+ + A+ + +M+ L ++GS F ++ S D + + V+TA +
Sbjct: 32 VDKNVQIAEAHAHDFE-DMVSLMPRNGSTFRPGTLLEDSKD------ADVVVITASIPAD 84
Query: 684 REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIG 863
+ R+ L N +++ L I+V+A++P D++ S +P +RVI
Sbjct: 85 KTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAANPCDVMAAAVHYGSKIPANRVIS 144
Query: 864 SGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+GT+L++ R + +L+ + + + ++GEHG +++ WS V + L L
Sbjct: 145 AGTNLETGRLKKMLAAKFNTSPDAIRASVLGEHGATAMIAWSTVKVGETTLEGL 198
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 283
Score = 61.3 bits (142), Expect = 5e-08
Identities = 44/145 (30%), Positives = 75/145 (51%), Gaps = 3/145 (2%)
Frame = +3
Query: 576 LQHGSAF--MXNAKIQSSTDYSITAGSKICVVTAGV-RQREGESRLDLVQRNTDVLKQII 746
LQH + I ST+ + + C+ +AG R ++R DL +N + K+
Sbjct: 38 LQHAQKLDIIHGMDIPVSTNPADLKDADYCIFSAGYSRSPNIKTRADLFDKNLPIAKESS 97
Query: 747 PQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIA 926
L +S L++ ++P+D+ T+ K S L + +V+G G LDS RF +L +GI
Sbjct: 98 ELLKGFSGK--LIVVTNPMDVFTWYFAKKSCLDESQVVGFGGLLDSRRFTVVLRS-IGI- 153
Query: 927 TTSCHGYIIGEHGXSSVPVWSAVNI 1001
G ++GEHG VP++S+++I
Sbjct: 154 --EAEGQVLGEHGEHQVPLFSSLDI 176
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 57.6 bits (133), Expect = 6e-07
Identities = 56/192 (29%), Positives = 84/192 (43%), Gaps = 5/192 (2%)
Frame = +3
Query: 513 VTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREG 692
+T N+ L A L+G +++H N S ++T +K V + G ++EG
Sbjct: 31 LTPNLCLYDPFAVGLEGVAEEIRHCGFEGLNLTFTSDIKEALT-DAKYIVSSGGAPRKEG 89
Query: 693 ESRLDLVQRNTDVLKQIIPQLIKYSPD-TILVIASDPVDILTYVTWKISGLPKHRVIGSG 869
+R DL++ N ++ Q+ + Y PD ++I +P DI VT SGL K + +
Sbjct: 90 MTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPADITGLVTLIYSGL-KPSQVTTL 148
Query: 870 TDLDSARFRYLLSDRLGI---ATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXNXIG 1040
LDS R + L+ GI T+ Y G HG S + G L DL IG
Sbjct: 149 AGLDSTRLQSELAKHFGIKQSLVTNTRTY--GGHGEQMAVFASTAKVNGTPLTDL---IG 203
Query: 1041 T-XXDPENWKXL 1073
T E W L
Sbjct: 204 TDKLTNEQWAEL 215
>UniRef50_Q1U8H4 Cluster: L-lactate dehydrogenase; n=2; Lactobacillus
reuteri|Rep: L-lactate dehydrogenase - Lactobacillus
reuteri 100-23
Length = 307
Score = 55.2 bits (127), Expect = 3e-06
Identities = 32/135 (23%), Positives = 64/135 (47%)
Frame = +3
Query: 627 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVD 806
DY+ A + + + G + + ++ + Q+ ++ K IL+ ++P +
Sbjct: 63 DYAALADADVLITAFGKSALMKQQPMAELETSYQQALQVGNKVFKSDFSGILINLTNPNE 122
Query: 807 ILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVW 986
+T V + GLP+ +VIG GT +++AR +++ +A + G++ G+H V W
Sbjct: 123 AITAVLQQKVGLPQKQVIGIGTVVETARLYRAIAEAAKVAAANVTGFVYGQHDGHQVFAW 182
Query: 987 SAVNIAGVRLXDLXN 1031
S V + G L N
Sbjct: 183 STVRVNGQPLTAAIN 197
>UniRef50_Q8Y860 Cluster: Lmo1057 protein; n=11; Listeria|Rep: Lmo1057
protein - Listeria monocytogenes
Length = 317
Score = 52.0 bits (119), Expect = 3e-05
Identities = 34/160 (21%), Positives = 80/160 (50%)
Frame = +3
Query: 528 ALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLD 707
A + ++ ++ K + D + S + + I S T ++ + I V Q E +++
Sbjct: 31 AEIYLIDDQAKTSVQDFDYASYYHADVTIHSGT-FNECRNADIVVFF----QEEMSNQIV 85
Query: 708 LVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSA 887
+ N ++ + + +++ I+++A+ +++ + + SGL +++I GT L ++
Sbjct: 86 SKEDNVALIIEKVKKMMATGFRGIVLVATAESNVVAALIKRFSGLSANQIITLGTMLATS 145
Query: 888 RFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAG 1007
F+ ++ I+ + HGYIIG++ +PVWS + G
Sbjct: 146 YFQVEIAKLFKISPKNVHGYIIGDNAEDVIPVWSRAFLGG 185
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 52.0 bits (119), Expect = 3e-05
Identities = 52/196 (26%), Positives = 85/196 (43%), Gaps = 5/196 (2%)
Frame = +3
Query: 501 LTQNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVR 680
L +T NI L A L+G +L H + N S +++ G+K V + G
Sbjct: 27 LMMKLTPNICLYDPYAPALEGVAEELYHCAFEGVNLTYTSDIKEALS-GAKYIVSSGGAA 85
Query: 681 QREGESRLDLVQRNTDVLKQIIPQLIKYSPDT-ILVIASDPVDILTYVTWKISGLPKHRV 857
++ G +R DL++ N ++ Q + +Y PD +V+ +P DI + +GL K
Sbjct: 86 RKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNPADITGLIVLLYAGL-KPSQ 144
Query: 858 IGSGTDLDSARFRYLLSDRLGIATT---SCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLX 1028
+ + LDS R + L L I + +C Y G HG S + G L +
Sbjct: 145 VSTLAALDSTRLQNELVKYLHIPASEIVNCRTY--GGHGEQMAVFASTTKVQGEALTKI- 201
Query: 1029 NXIGTXXDP-ENWKXL 1073
I T P ++W+ L
Sbjct: 202 --IDTPRMPMQDWEDL 215
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 49.6 bits (113), Expect = 2e-04
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 3/126 (2%)
Frame = +3
Query: 612 IQSSTDYSITAGS-KICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYS-PDTILV 785
I S+T+ ++ + + ++ AGV ++ G R DL+ N V++ L YS D +V
Sbjct: 75 IISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGTYSNKDVRVV 134
Query: 786 IASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYII-GEH 962
+ ++P + YV K SG+P + T LD R +++ +G H I+ G H
Sbjct: 135 VVANPANTNAYVICKTSGIPPEHITAL-TRLDQNRATAFVANEVGCQPEFVHNIIVWGNH 193
Query: 963 GXSSVP 980
+ P
Sbjct: 194 SNTMQP 199
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 47.6 bits (108), Expect = 7e-04
Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 6/125 (4%)
Frame = +3
Query: 561 GEMMDLQHGSAFMXNAKIQSSTDY-SITAGSKICVVTAGVRQREGESRLDLVQRNTDVLK 737
G DL H + + D+ ++ GS++ +VTAG+ ++ G +R DL + N +++
Sbjct: 41 GVAKDLSHINTNSDSEGYNKDEDFKNLLEGSELVIVTAGIPRKPGMTRDDLFKINAKIIQ 100
Query: 738 QIIPQLIKYSP-DTILVIASDPVDILTYV---TWKISG-LPKHRVIGSGTDLDSARFRYL 902
+ + K++P L+I S+PV+ L V T KI+G L +V G T LD R +
Sbjct: 101 NLTVKYAKFAPVHCKLLIISNPVNSLIPVVIETLKINGRLNPSQVFGI-TMLDIIRSQTF 159
Query: 903 LSDRL 917
L+D L
Sbjct: 160 LNDLL 164
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 47.2 bits (107), Expect = 0.001
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 4/119 (3%)
Frame = +3
Query: 645 GSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYV- 821
G + ++ AG+ ++ G++R DL + N D+ K I+ KY PD +L + +PV+ +
Sbjct: 158 GCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPDAMLGMIVNPVNSVVPAM 217
Query: 822 --TWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEH-GXSSVPVWS 989
+K GL +++G T LD R + RL + +IG H G + +P++S
Sbjct: 218 AELYKKKGLDPMKIVGI-TTLDVVRANKFVV-RLPAPPDRVNVPVIGGHAGTTILPLFS 274
>UniRef50_Q039N1 Cluster: Malate/lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: Malate/lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 296
Score = 45.2 bits (102), Expect = 0.004
Identities = 24/109 (22%), Positives = 50/109 (45%)
Frame = +3
Query: 705 DLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDS 884
D ++ N +++++ + +++A ++ TY + SG+ K +V+G GT +
Sbjct: 81 DFIETNIAAIRKVLNSAMAAGFTGRIIVAMTRDELFTYFAQRFSGVNKSQVVGLGTFGAT 140
Query: 885 ARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDLXN 1031
RF L+ RL + Y++G + V +WS + + L N
Sbjct: 141 WRFEQFLAARLAVPAKHVTAYVVGTR-QAPVLIWSRAYVGATPVLRLLN 188
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 45.2 bits (102), Expect = 0.004
Identities = 35/148 (23%), Positives = 70/148 (47%), Gaps = 4/148 (2%)
Frame = +3
Query: 558 KGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLK 737
+G +DL H + + + G+ + +++AG+ +R G + DL N +
Sbjct: 46 RGVAVDLSHFPRKVKVTGYPTKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVN 105
Query: 738 QIIPQLIKYSPDTILVIASDPVDILTYV---TWKISGLPKHRVIGSGTDLDSARFRYLLS 908
++ + +Y+P ++L I S+P++ + V T + +G+ R + L+ R R +L
Sbjct: 106 ELSAAVARYAPKSVLAIISNPLNSMVPVAAETLQRAGVYDPRKLFGIISLNMMRARKMLG 165
Query: 909 DRLGIATTSCHGYIIGEH-GXSSVPVWS 989
D G +IG H G + VP++S
Sbjct: 166 DFTGQDPEMLDVPVIGGHSGQTIVPLFS 193
>UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular
organisms|Rep: Malate dehydrogenase - Oryza sativa
(Rice)
Length = 352
Score = 41.9 bits (94), Expect = 0.034
Identities = 33/160 (20%), Positives = 70/160 (43%), Gaps = 2/160 (1%)
Frame = +3
Query: 507 QNVTNNIALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQR 686
Q V ++ + + AN L G M+L + + + +S + G + ++ G +R
Sbjct: 56 QPVVLHLLDLPVAANALNGVRMELIDAALPLLRGVVATSDEAEAFKGVNVAILIGGWPRR 115
Query: 687 EGESRLDLVQRNTDVLKQIIPQLIKY-SPDTILVIASDPVDILTYVTWKISGLPKHRVIG 863
+G R DL+ +N + K L ++ +P+ +++ ++P + V + + + I
Sbjct: 116 DGMERKDLISKNVTIYKSQASALQQHAAPNCKVLVVANPANTNALVLKEFAPAIPAKNIT 175
Query: 864 SGTDLDSARFRYLLSDRLGIATTSCHGYII-GEHGXSSVP 980
T LD R ++++L + II G H + P
Sbjct: 176 CLTRLDHNRALGQVAEKLNVHVGDVKNAIIWGNHSSTQFP 215
>UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=124;
cellular organisms|Rep: Malate dehydrogenase, cytoplasmic
- Homo sapiens (Human)
Length = 334
Score = 40.7 bits (91), Expect = 0.079
Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 3/161 (1%)
Frame = +3
Query: 543 MANKLKGEMMDLQHGSAFMXNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRN 722
M L G +M+LQ + + I + + + ++ + +REG R DL++ N
Sbjct: 46 MMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKAN 105
Query: 723 TDVLKQIIPQLIKYSPDTI-LVIASDPVDILTYVTWKIS-GLPKHRVIGSGTDLDSARFR 896
+ K L KY+ ++ +++ +P + K + +PK T LD R +
Sbjct: 106 VKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKEN-FSCLTRLDHNRAK 164
Query: 897 YLLSDRLGIATTSCHGYII-GEHGXSSVPVWSAVNIAGVRL 1016
++ +LG+ II G H + P VN A V+L
Sbjct: 165 AQIALKLGVTANDVKNVIIWGNHSSTQYP---DVNHAKVKL 202
>UniRef50_Q1WU75 Cluster: Lactate/malate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
Lactate/malate dehydrogenase - Lactobacillus salivarius
subsp. salivarius (strain UCC118)
Length = 294
Score = 39.5 bits (88), Expect = 0.18
Identities = 28/109 (25%), Positives = 54/109 (49%)
Frame = +3
Query: 699 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLPKHRVIGSGTDL 878
R + Q+N+ + K ++ + + + I+V+ S+ +L K +GL +V+G GT +
Sbjct: 80 RDNFAQKNSWIQK-VVTEAVANGFNGIVVLDSNKDYLLINEILKYTGLSSRQVLGLGTSI 138
Query: 879 DSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWSAVNIAGVRLXDL 1025
+S +++ +LGI + +IG S V +WS +A L L
Sbjct: 139 ESEVVARMVAKKLGINSNYIQTSVIGTRDKSFV-LWSKGRVAEASLMSL 186
>UniRef50_Q03QL8 Cluster: Malate/lactate dehydrogenase; n=1;
Lactobacillus brevis ATCC 367|Rep: Malate/lactate
dehydrogenase - Lactobacillus brevis (strain ATCC 367 /
JCM 1170)
Length = 302
Score = 37.1 bits (82), Expect = 0.97
Identities = 21/67 (31%), Positives = 32/67 (47%)
Frame = +3
Query: 810 LTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSSVPVWS 989
L+Y WK SGL +++ G GT + L+D LG+ + + +IG + VWS
Sbjct: 117 LSYFAWKFSGLQANQIWGLGTYPLARLLTARLADHLGVGSAAVQATVIGT-ADLPIVVWS 175
Query: 990 AVNIAGV 1010
I V
Sbjct: 176 RTYIGPV 182
>UniRef50_A2YRW8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 127
Score = 36.3 bits (80), Expect = 1.7
Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 4/46 (8%)
Frame = +3
Query: 696 SRLDLVQRN--TDVLKQIIPQLIKYSPDTILVIASDPV--DILTYV 821
++L+L++ N +L +I+P L + SP+ LV+ SDP D+LTYV
Sbjct: 3 TKLELMRSNYLKKLLTEIVPALAENSPEAALVVVSDPPVDDVLTYV 48
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 35.5 bits (78), Expect = 3.0
Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 5/119 (4%)
Frame = +3
Query: 648 SKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVD----ILT 815
S I VV + E + L RN ++K + + K+SP + + I +P++ + +
Sbjct: 97 SNIIVVLSCCHAAEPTNYASLFDRNAPIVKDLATSIAKFSPKSTVAIGVEPINSVVPMFS 156
Query: 816 YVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIGEHGXSS-VPVWS 989
+ K + + G T +D R +++ LG+ I+G H + VPV S
Sbjct: 157 EIMKKYGHYNPYSIFGI-TTVDVVRTNKFVAEILGLEPECVTVPIVGGHSEKTIVPVLS 214
>UniRef50_A4XD44 Cluster: ABC transporter related; n=2;
Salinispora|Rep: ABC transporter related - Salinispora
tropica CNB-440
Length = 214
Score = 34.7 bits (76), Expect = 5.2
Identities = 17/44 (38%), Positives = 24/44 (54%)
Frame = -3
Query: 509 LRQHRESCGXPNLTDPDNGHLAPSCVHLRVHGLEQLLTGTPACG 378
+R+H + N DPD+GH+A CV L + GL L T + G
Sbjct: 96 VREHLDLVRVVNGGDPDDGHIAELCVTLGLTGLSDSLPSTLSSG 139
>UniRef50_Q6ZCA3 Cluster: Putative uncharacterized protein
P0547A06.25; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
P0547A06.25 - Oryza sativa subsp. japonica (Rice)
Length = 187
Score = 34.7 bits (76), Expect = 5.2
Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 4/45 (8%)
Frame = +3
Query: 696 SRLDLVQRN--TDVLKQIIPQLIKYSPDTILVIASDPV--DILTY 818
++L+L++ N +L +I+P L + SP+ LV+ SDP D+LTY
Sbjct: 3 TKLELMRSNYLKKLLTEIVPALAENSPEAALVVVSDPPVDDVLTY 47
>UniRef50_UPI0000F20185 Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 173
Score = 34.3 bits (75), Expect = 6.8
Identities = 18/38 (47%), Positives = 20/38 (52%)
Frame = -1
Query: 448 LLQVASTCACTGWNSCLQGXQLVGVRAMPVGVVWRQRK 335
LLQ S C CTGW SCL Q G V+WR +K
Sbjct: 136 LLQSLSKC-CTGWISCLISEQCCGTLMPHETVMWRLQK 172
>UniRef50_P40557 Cluster: Putative protein disulfide-isomerase
YIL005W precursor; n=2; Saccharomyces cerevisiae|Rep:
Putative protein disulfide-isomerase YIL005W precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 701
Score = 34.3 bits (75), Expect = 6.8
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Frame = +3
Query: 525 IALVXMMANKLKGEMMDLQHGSAFMXNAKIQSSTDYS--ITAGSKICVVTAGVRQREGES 698
+ALV + NK + D +G +AK D++ SK +T G +++
Sbjct: 258 VALV--LPNKTSNNLFDYPNG----YSAKSDGYVDFARRTFTNSKFPNITEGELEKKANR 311
Query: 699 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASDPVDILTYVTWKISGLP 845
+D +Q V I + Y P+T+++ + DIL Y+ +S +P
Sbjct: 312 DIDFLQERGRVTNNDIHLVFSYDPETVVI---EDFDILEYLIEPLSKIP 357
>UniRef50_A5I533 Cluster: Putative malate/lactate dehydrogenase;
n=4; Clostridium botulinum|Rep: Putative malate/lactate
dehydrogenase - Clostridium botulinum A str. ATCC 3502
Length = 407
Score = 33.9 bits (74), Expect = 9.0
Identities = 24/67 (35%), Positives = 27/67 (40%)
Frame = +3
Query: 777 ILVIASDPVDILTYVTWKISGLPKHRVIGSGTDLDSARFRYLLSDRLGIATTSCHGYIIG 956
I I SDPVD+L K GL +V G G + SAR Y S G G
Sbjct: 238 IFAIVSDPVDLLCKSALK-EGLAPEQVRGYGLGVMSARAAYYADKDPKFKNYSMEGRAFG 296
Query: 957 EHGXSSV 977
HG V
Sbjct: 297 PHGEGLV 303
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 889,560,814
Number of Sequences: 1657284
Number of extensions: 16063417
Number of successful extensions: 45317
Number of sequences better than 10.0: 153
Number of HSP's better than 10.0 without gapping: 43053
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45178
length of database: 575,637,011
effective HSP length: 103
effective length of database: 404,936,759
effective search space used: 129984699639
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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