Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP26_F_D07
(1222 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VEJ3 Cluster: Pyrroline-5-carboxylate reductase; n=14... 275 1e-72
UniRef50_A6C9N7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 229 1e-58
UniRef50_P54904 Cluster: Pyrroline-5-carboxylate reductase; n=11... 214 3e-54
UniRef50_Q8MUT0 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 210 7e-53
UniRef50_Q5EI64 Cluster: Pyrroline-5-carboxylate reductase; n=10... 208 3e-52
UniRef50_UPI000058613C Cluster: PREDICTED: similar to pyrroline-... 204 5e-51
UniRef50_P32322 Cluster: Pyrroline-5-carboxylate reductase 1; n=... 202 1e-50
UniRef50_A7SQR3 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 202 2e-50
UniRef50_A7HA48 Cluster: Pyrroline-5-carboxylate reductase; n=16... 198 3e-49
UniRef50_Q8GE04 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 197 4e-49
UniRef50_A6PTF6 Cluster: Pyrroline-5-carboxylate reductase precu... 196 1e-48
UniRef50_Q2BA85 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 194 4e-48
UniRef50_A5D185 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 193 7e-48
UniRef50_Q9HH99 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 193 7e-48
UniRef50_A7RN43 Cluster: Predicted protein; n=1; Nematostella ve... 193 9e-48
UniRef50_Q00XH4 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 192 2e-47
UniRef50_A7SC14 Cluster: Predicted protein; n=1; Nematostella ve... 192 2e-47
UniRef50_A0WB61 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 185 2e-45
UniRef50_Q6NP47 Cluster: Pyrroline-5-carboxylate reductase; n=10... 183 1e-44
UniRef50_UPI00015B577C Cluster: PREDICTED: similar to GA19292-PA... 177 5e-43
UniRef50_UPI000051A719 Cluster: PREDICTED: similar to Pyrroline ... 176 1e-42
UniRef50_A5N0V3 Cluster: ProC2; n=1; Clostridium kluyveri DSM 55... 175 3e-42
UniRef50_Q97E64 Cluster: Pyrroline-5-carboxylate reductase; n=10... 174 3e-42
UniRef50_Q1IRM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 174 3e-42
UniRef50_Q4SMN2 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 174 4e-42
UniRef50_UPI0000D556D2 Cluster: PREDICTED: similar to CG6009-PA;... 173 1e-41
UniRef50_A6TR68 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 173 1e-41
UniRef50_Q8RA68 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 172 2e-41
UniRef50_A4M789 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 172 2e-41
UniRef50_Q7UTG7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 171 4e-41
UniRef50_P74572 Cluster: Pyrroline-5-carboxylate reductase; n=14... 167 7e-40
UniRef50_UPI00015C417B Cluster: pyrroline-5-carboxylate reductas... 166 9e-40
UniRef50_Q53H96 Cluster: Pyrroline-5-carboxylate reductase-like ... 166 9e-40
UniRef50_Q9X8G1 Cluster: Pyrroline-5-carboxylate reductase; n=11... 166 1e-39
UniRef50_Q6NJK7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 161 3e-38
UniRef50_A6G2U4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 161 3e-38
UniRef50_Q8KG91 Cluster: Pyrroline-5-carboxylate reductase; n=10... 161 4e-38
UniRef50_Q97R93 Cluster: Pyrroline-5-carboxylate reductase; n=13... 160 6e-38
UniRef50_Q0SF18 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 159 2e-37
UniRef50_Q27722 Cluster: Pyrroline carboxylate reductase; n=8; P... 158 2e-37
UniRef50_P0A9L9 Cluster: Pyrroline-5-carboxylate reductase; n=65... 156 1e-36
UniRef50_A6BFA0 Cluster: Putative uncharacterized protein; n=1; ... 156 1e-36
UniRef50_A0LDU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 156 1e-36
UniRef50_Q1F0K7 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 155 2e-36
UniRef50_Q4QFY6 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 155 3e-36
UniRef50_Q0AYD4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 153 7e-36
UniRef50_Q8S488 Cluster: Delta-1-pyrroline-5-carboxylate reducta... 153 7e-36
UniRef50_Q3AAH4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 152 2e-35
UniRef50_A3DD78 Cluster: Pyrroline-5-carboxylate reductase precu... 152 2e-35
UniRef50_A5Z6I9 Cluster: Putative uncharacterized protein; n=1; ... 151 5e-35
UniRef50_Q67QH2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 150 6e-35
UniRef50_Q233Y5 Cluster: Pyrroline-5-carboxylate reductase famil... 150 6e-35
UniRef50_Q86ER8 Cluster: Clone ZZD150 mRNA sequence; n=3; Schist... 150 8e-35
UniRef50_Q2ZZM3 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 148 3e-34
UniRef50_P14383 Cluster: Pyrroline-5-carboxylate reductase 1; n=... 148 3e-34
UniRef50_A0K0A3 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 147 6e-34
UniRef50_P54552 Cluster: Pyrroline-5-carboxylate reductase 2; n=... 147 6e-34
UniRef50_A4J3P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 146 1e-33
UniRef50_P0C1E4 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 146 1e-33
UniRef50_Q11141 Cluster: Pyrroline-5-carboxylate reductase; n=18... 145 2e-33
UniRef50_Q6AAZ1 Cluster: Putative delta-1-pyrroline-5-carboxylat... 145 2e-33
UniRef50_Q9P7Y7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 145 2e-33
UniRef50_Q6AL13 Cluster: Related to pyrroline-5-carboxylate redu... 142 1e-32
UniRef50_Q836Y3 Cluster: Pyrroline-5-carboxylate reductase, puta... 141 4e-32
UniRef50_Q5KFS4 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 140 5e-32
UniRef50_Q8F631 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 140 7e-32
UniRef50_A5WCA1 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 138 3e-31
UniRef50_Q831S6 Cluster: Pyrroline-5-carboxylate reductase, puta... 138 4e-31
UniRef50_Q64E79 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 138 4e-31
UniRef50_Q48P99 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 137 6e-31
UniRef50_Q5KXH0 Cluster: Pyrroline-5-carboxylate reductase; n=13... 136 1e-30
UniRef50_Q8U084 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 136 1e-30
UniRef50_Q1FII0 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 135 2e-30
UniRef50_P22008 Cluster: Pyrroline-5-carboxylate reductase; n=21... 135 3e-30
UniRef50_A2QIA2 Cluster: Catalytic activity: L-proline + NAD(P)(... 134 4e-30
UniRef50_Q0ICK3 Cluster: Pyrroline-5-carboxylate reductase; n=17... 134 6e-30
UniRef50_A2EU21 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 134 6e-30
UniRef50_Q02WW5 Cluster: Pyrroline-5-carboxylate reductase; n=12... 132 2e-29
UniRef50_A7GVZ9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 131 4e-29
UniRef50_A1TY17 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 131 4e-29
UniRef50_Q8EU76 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 130 7e-29
UniRef50_Q3Y1B7 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 130 7e-29
UniRef50_Q88Z19 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 130 9e-29
UniRef50_P54893 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 130 9e-29
UniRef50_Q6KZ51 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 129 2e-28
UniRef50_Q312A7 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 128 2e-28
UniRef50_A5UQB8 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 128 2e-28
UniRef50_Q9KCR6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 128 3e-28
UniRef50_Q8YCL9 Cluster: PYRROLINE-5-CARBOXYLATE REDUCTASE; n=11... 127 7e-28
UniRef50_Q83A21 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 126 9e-28
UniRef50_Q6N1N9 Cluster: Pyrroline-5-carboxylate reductase; n=23... 126 9e-28
UniRef50_Q6CEN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 126 9e-28
UniRef50_Q20848 Cluster: Putative pyrroline-5-carboxylate reduct... 126 9e-28
UniRef50_A3IBB9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 126 1e-27
UniRef50_Q0VL32 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 126 2e-27
UniRef50_Q82X95 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 124 4e-27
UniRef50_A3LST6 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 124 4e-27
UniRef50_Q1GJ10 Cluster: Pyrroline-5-carboxylate reductase; n=24... 123 8e-27
UniRef50_A5CND2 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 123 8e-27
UniRef50_Q8DJK6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 122 1e-26
UniRef50_A6GTV0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 122 2e-26
UniRef50_A6DTF8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 122 2e-26
UniRef50_Q9HLT6 Cluster: Pyrroline-5-carboxylate reductase relat... 122 2e-26
UniRef50_A3H628 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 122 2e-26
UniRef50_Q12740 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 121 3e-26
UniRef50_Q0C2D9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 121 4e-26
UniRef50_A1AVF5 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 121 4e-26
UniRef50_Q9CPE8 Cluster: Pyrroline-5-carboxylate reductase; n=93... 121 4e-26
UniRef50_Q1AVY1 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 120 6e-26
UniRef50_A1H9S1 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 120 6e-26
UniRef50_Q0EXW9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 120 8e-26
UniRef50_A3HTL9 Cluster: Putative pyrroline-5-carboxylate reduct... 120 1e-25
UniRef50_Q89DI5 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 119 2e-25
UniRef50_A1IB74 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 119 2e-25
UniRef50_P27771 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 119 2e-25
UniRef50_Q3MCP7 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 118 3e-25
UniRef50_Q1UAB2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 118 4e-25
UniRef50_A3UFN9 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 117 5e-25
UniRef50_Q1YVF3 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 117 7e-25
UniRef50_Q9PA08 Cluster: Pyrroline-5-carboxylate reductase; n=14... 116 9e-25
UniRef50_Q1MPA3 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 116 1e-24
UniRef50_A5FLP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 116 2e-24
UniRef50_A4XKQ2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 115 2e-24
UniRef50_Q9YFV4 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 115 3e-24
UniRef50_A6Q4P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 114 4e-24
UniRef50_P32263 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 114 4e-24
UniRef50_Q8G5S6 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 114 5e-24
UniRef50_Q18YN1 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 114 5e-24
UniRef50_A3ERR0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 114 5e-24
UniRef50_O66553 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 114 5e-24
UniRef50_Q4TIV0 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 113 9e-24
UniRef50_A7BDU0 Cluster: Putative uncharacterized protein; n=1; ... 113 9e-24
UniRef50_Q12641 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 113 9e-24
UniRef50_Q21EI2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 112 2e-23
UniRef50_A0NYJ6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 112 2e-23
UniRef50_Q0U2X1 Cluster: Putative uncharacterized protein; n=1; ... 112 2e-23
UniRef50_A6SCY1 Cluster: Putative uncharacterized protein; n=2; ... 112 2e-23
UniRef50_Q5QY55 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 111 3e-23
UniRef50_A4BKC4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 111 3e-23
UniRef50_Q6LML8 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 111 4e-23
UniRef50_Q5WH55 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 111 4e-23
UniRef50_Q04FB4 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 111 4e-23
UniRef50_A4SZT4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 111 4e-23
UniRef50_A0Z2R8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 111 4e-23
UniRef50_UPI000038E2C3 Cluster: hypothetical protein Faci_030013... 111 5e-23
UniRef50_Q2UTF9 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 111 5e-23
UniRef50_Q087E8 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 110 6e-23
UniRef50_Q3ZWQ2 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 110 8e-23
UniRef50_Q2S8M4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 110 8e-23
UniRef50_Q974L3 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 109 1e-22
UniRef50_Q9WZ47 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 109 2e-22
UniRef50_Q7VYN6 Cluster: Pyrroline-5-carboxylate reductase; n=45... 108 3e-22
UniRef50_Q7M801 Cluster: PUTATIVE PYRROLINE-5-CARBOXYLATE REDUCT... 107 4e-22
UniRef50_Q6MC43 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 107 4e-22
UniRef50_Q5XE84 Cluster: Pyrroline-5-carboxylate reductase; n=14... 107 4e-22
UniRef50_Q1PLB2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 106 1e-21
UniRef50_Q5NMY3 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 105 2e-21
UniRef50_Q9KEG5 Cluster: Pyrroline-5-carboxylate reductase; n=11... 104 4e-21
UniRef50_A2QNB5 Cluster: Catalytic activity: L-proline + NAD(P)(... 104 4e-21
UniRef50_A7D089 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 104 5e-21
UniRef50_A1W308 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 103 9e-21
UniRef50_Q5WIM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 102 2e-20
UniRef50_A4R602 Cluster: Putative uncharacterized protein; n=1; ... 101 3e-20
UniRef50_Q7WJW6 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 100 9e-20
UniRef50_Q9FDK7 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 100 9e-20
UniRef50_Q9K1N1 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 99 1e-19
UniRef50_A6NV19 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 99 1e-19
UniRef50_Q5HFR9 Cluster: Pyrroline-5-carboxylate reductase; n=16... 99 1e-19
UniRef50_Q03V33 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 99 2e-19
UniRef50_A5VEU4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 99 2e-19
UniRef50_A4A9D5 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 99 2e-19
UniRef50_Q5ZP97 Cluster: Pyrroline carboxylate reductase-like pr... 99 3e-19
UniRef50_A6VSQ3 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 99 3e-19
UniRef50_Q0BPP7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 98 5e-19
UniRef50_UPI0000E87E64 Cluster: pyrroline-5-carboxylate reductas... 97 6e-19
UniRef50_Q8D3C2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 97 8e-19
UniRef50_Q0PQR2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 97 8e-19
UniRef50_Q5ZTZ3 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 96 2e-18
UniRef50_Q11WK0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 95 2e-18
UniRef50_A6QB49 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 95 4e-18
UniRef50_A7EEE1 Cluster: Putative uncharacterized protein; n=1; ... 95 4e-18
UniRef50_A6RSV4 Cluster: Putative uncharacterized protein; n=1; ... 95 4e-18
UniRef50_Q2PIP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 94 8e-18
UniRef50_A2BJN9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 94 8e-18
UniRef50_Q9AAU9 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 93 2e-17
UniRef50_Q1VVL6 Cluster: Pyrroline-5-carboxylate reductase; n=9;... 93 2e-17
UniRef50_Q8A6I2 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 92 2e-17
UniRef50_UPI00015BCA3C Cluster: UPI00015BCA3C related cluster; n... 92 3e-17
UniRef50_Q7YYR6 Cluster: Pyrroline-5-carboxylate reductase, poss... 92 3e-17
UniRef50_Q0UG51 Cluster: Putative uncharacterized protein; n=1; ... 92 3e-17
UniRef50_Q0CFR0 Cluster: Predicted protein; n=3; Aspergillus|Rep... 92 3e-17
UniRef50_UPI0000E1F031 Cluster: PREDICTED: similar to Pyrroline-... 91 5e-17
UniRef50_A7JJ83 Cluster: Pyrroline-5-carboxylate reductase; n=11... 91 7e-17
UniRef50_A7C3U2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 89 2e-16
UniRef50_Q1GX51 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 89 3e-16
UniRef50_A6LE67 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 89 3e-16
UniRef50_A0M2T1 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 89 3e-16
UniRef50_Q18J37 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 89 3e-16
UniRef50_Q5FRU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 87 9e-16
UniRef50_A7LUS1 Cluster: Putative uncharacterized protein; n=1; ... 87 9e-16
UniRef50_Q88GE6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 86 2e-15
UniRef50_Q2NCY1 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 86 2e-15
UniRef50_Q1U6D2 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 85 3e-15
UniRef50_A3X4C4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 85 3e-15
UniRef50_A7AD19 Cluster: Putative uncharacterized protein; n=1; ... 85 4e-15
UniRef50_A0RR69 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 85 4e-15
UniRef50_Q4HSX5 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 85 5e-15
UniRef50_Q0P9H8 Cluster: Pyrroline-5-carboxylate reductase; n=10... 83 1e-14
UniRef50_Q54IL7 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 83 1e-14
UniRef50_Q1NBI0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 83 2e-14
UniRef50_A3VSN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 83 2e-14
UniRef50_Q4WFG1 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 83 2e-14
UniRef50_UPI000050FC3D Cluster: COG0345: Pyrroline-5-carboxylate... 81 6e-14
UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=... 80 1e-13
UniRef50_Q1M3U8 Cluster: Putative pyrroline-5-carboxylate reduct... 79 3e-13
UniRef50_A3CV24 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 79 3e-13
UniRef50_A0HA22 Cluster: NADP oxidoreductase, coenzyme F420-depe... 77 7e-13
UniRef50_A3M414 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 77 1e-12
UniRef50_Q0AL89 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 76 2e-12
UniRef50_A1B1A3 Cluster: NADP oxidoreductase, coenzyme F420-depe... 76 2e-12
UniRef50_A6DA85 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 76 2e-12
UniRef50_Q67T73 Cluster: ComE operon protein 4; n=1; Symbiobacte... 75 4e-12
UniRef50_Q7VHX1 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 75 5e-12
UniRef50_Q5FK14 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 74 9e-12
UniRef50_Q6MQK1 Cluster: ProC protein; n=1; Bdellovibrio bacteri... 73 2e-11
UniRef50_A3Y9M8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 71 6e-11
UniRef50_A3K0L9 Cluster: Putative pyrroline-5-carboxylate reduct... 71 6e-11
UniRef50_A5EV67 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 71 8e-11
UniRef50_Q41BC1 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 69 2e-10
UniRef50_Q0G398 Cluster: Putative pyrroline-5-carboxylate reduct... 69 3e-10
UniRef50_A2A043 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 68 4e-10
UniRef50_A3SP40 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 68 6e-10
UniRef50_Q83FH8 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 67 1e-09
UniRef50_A3UDP5 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 67 1e-09
UniRef50_Q5FGR8 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 63 1e-08
UniRef50_Q4ML40 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 62 3e-08
UniRef50_O25773 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 62 4e-08
UniRef50_Q59UW8 Cluster: Putative uncharacterized protein; n=2; ... 60 9e-08
UniRef50_Q2FQL0 Cluster: NADP oxidoreductase, coenzyme F420-depe... 57 1e-06
UniRef50_A4R344 Cluster: Putative uncharacterized protein; n=1; ... 54 8e-06
UniRef50_UPI0000E45EAB Cluster: PREDICTED: similar to pyrroline-... 54 1e-05
UniRef50_Q9KD86 Cluster: Non-essential gene for competence; n=2;... 54 1e-05
UniRef50_Q92BW8 Cluster: Lin1424 protein; n=12; Listeria|Rep: Li... 53 1e-05
UniRef50_Q4FKY2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 53 1e-05
UniRef50_A6RTE4 Cluster: Putative uncharacterized protein; n=2; ... 51 7e-05
UniRef50_A1FCT9 Cluster: Pyrroline-5-carboxylate reductase-like;... 50 9e-05
UniRef50_UPI00015BAEC8 Cluster: pyrroline-5-carboxylate reductas... 50 2e-04
UniRef50_UPI0000DAE5EB Cluster: hypothetical protein Rgryl_01000... 43 0.014
UniRef50_Q8ZW86 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 40 0.13
UniRef50_Q8TGP2 Cluster: Uncharacterized protein YER023C-A; n=2;... 40 0.17
UniRef50_A4IGE0 Cluster: Pycrl protein; n=1; Danio rerio|Rep: Py... 38 0.40
UniRef50_Q16V76 Cluster: Set domain protein; n=1; Aedes aegypti|... 36 2.1
UniRef50_A2C5X0 Cluster: Putative uncharacterized protein; n=1; ... 35 3.7
UniRef50_Q3K4H0 Cluster: Rhs element Vgr protein precursor; n=4;... 35 4.9
UniRef50_A1WWC4 Cluster: Transcriptional regulator, Fis family p... 35 4.9
UniRef50_Q57Z15 Cluster: Putative uncharacterized protein; n=1; ... 34 6.5
UniRef50_UPI0000ECBD99 Cluster: Pyrroline-5-carboxylate reductas... 34 8.6
UniRef50_Q7NSK8 Cluster: Malonyl CoA-acyl carrier protein transa... 34 8.6
UniRef50_Q01U58 Cluster: Ig family protein precursor; n=1; Solib... 34 8.6
UniRef50_Q24I44 Cluster: Putative uncharacterized protein; n=1; ... 34 8.6
UniRef50_Q0W1B5 Cluster: Putative ATP-dependent phosphofructokin... 34 8.6
>UniRef50_Q9VEJ3 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Endopterygota|Rep: Pyrroline-5-carboxylate reductase -
Drosophila melanogaster (Fruit fly)
Length = 273
Score = 275 bits (675), Expect = 1e-72
Identities = 139/263 (52%), Positives = 181/263 (68%), Gaps = 1/263 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KIGF+GGG +A ALA GF++AGLAKP+ + AS HP+D S ++FQ LG + +N
Sbjct: 6 KIGFLGGGNMAKALAKGFLAAGLAKPNTLIASVHPADKLSLQSFQSLGVETVIKNAPVVQ 65
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L EI+ P + KLF+SVAMGIT++T+ES+L +ARVIRVMPN
Sbjct: 66 QSDVVFVSVKPQVVPSVLSEIQ--PLSSGKLFLSVAMGITLSTIESSLSPQARVIRVMPN 123
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
PA+V G + F RG+KAT DA +T +L ++VGTC+ V E Q+D +TALSGSGPAYV++
Sbjct: 124 LPAVVCSGCSVFVRGSKATDADADITQKLLQSVGTCEPVDESQLDVVTALSGSGPAYVFV 183
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTY 829
+IE+LADG V G+PRDLA RLA+QT LG+ MV+ +G HP LKD VTSPAGSTA
Sbjct: 184 MIEALADGAVHMGMPRDLAYRLASQTVLGAGHMVRDSGMHPGQLKDGVTSPAGSTAAALR 243
Query: 830 HLEKNGFRSAIIGAVSAAVDRCK 898
LE +GFR+A+ GAV A RC+
Sbjct: 244 QLELSGFRAAVSGAVEQATLRCR 266
>UniRef50_A6C9N7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Planctomyces maris DSM 8797|Rep: Pyrroline-5-carboxylate
reductase - Planctomyces maris DSM 8797
Length = 274
Score = 229 bits (559), Expect = 1e-58
Identities = 124/261 (47%), Positives = 163/261 (62%), Gaps = 1/261 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
K+GFIG GR+A ALA G IS+G D + AS + AS K Q GA ++ N
Sbjct: 8 KVGFIGAGRMATALAGGLISSGFTTKDHVCAS-DTYEAASEKFAQETGARSVSSNQQVME 66
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L+EIK+ ++++ L IS+A G ++ L R+IRVMPN
Sbjct: 67 QAEIIILSVKPQQIPDVLQEIKSSVTSQH-LLISIAAGCPLSLFLDTLGEFTRMIRVMPN 125
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TP LVK+GA+AF+RG +A+ EDA L L VG EVPE Q+DA+T LSGSGPAY+Y
Sbjct: 126 TPCLVKQGASAFARGGQASTEDATLVESLLSTVGIAFEVPESQLDAVTGLSGSGPAYIYQ 185
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
+IE+L+DGGVR GLPR +A +LAAQT G+A MV +TG+HP LKD VTSP G+T G +
Sbjct: 186 VIEALSDGGVRVGLPRQIATQLAAQTVKGAAEMVLQTGEHPGTLKDAVTSPGGTTIAGIH 245
Query: 830 HLEKNGFRSAIIGAVSAAVDR 892
LE G R++++ AVSAA R
Sbjct: 246 ALEAGGLRNSLMNAVSAATSR 266
>UniRef50_P54904 Cluster: Pyrroline-5-carboxylate reductase; n=11;
core eudicotyledons|Rep: Pyrroline-5-carboxylate
reductase - Arabidopsis thaliana (Mouse-ear cress)
Length = 276
Score = 214 bits (523), Expect = 3e-54
Identities = 117/271 (43%), Positives = 163/271 (60%), Gaps = 2/271 (0%)
Frame = +2
Query: 92 LPL-IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATAL 268
LP+ E+ K+GFIG G++A ++A G +++G+ P+ I + H S++ F+ G
Sbjct: 4 LPIPAESFKVGFIGAGKMAESIARGVVASGVLPPNRICTAVH-SNLNRRDVFESFGVNVF 62
Query: 269 FENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA 448
+ A+ E+K+ S KNK+ +SVA GI + ++ +
Sbjct: 63 STSEEVVKESDVVIFSVKPQVVKKAVTELKSKLS-KNKILVSVAAGIKLNDLQE-WSGQD 120
Query: 449 RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSG 628
R IRVMPNTPA V E A+ S GT AT ED + + LF AVG + E DA+T LSG
Sbjct: 121 RFIRVMPNTPAAVGEAASVMSLGTGATEEDGAIVAMLFGAVGKILKADEKMFDAVTGLSG 180
Query: 629 SGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPA 805
SGPAY+++ IE+LADGGV GLPR+LAL LA+QT LG+A MV KTG HP +LKD+VTSP
Sbjct: 181 SGPAYIFLAIEALADGGVAAGLPRELALSLASQTVLGAATMVSKTGKHPGVLKDDVTSPG 240
Query: 806 GSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
G+T G + LEK FR+ ++ AV AA R +
Sbjct: 241 GTTIAGVHELEKGSFRATLMNAVVAAAKRSR 271
>UniRef50_Q8MUT0 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Tigriopus californicus|Rep: Pyrroline-5-carboxylate
reductase - Tigriopus californicus (Marine copepod)
Length = 270
Score = 210 bits (512), Expect = 7e-53
Identities = 109/264 (41%), Positives = 161/264 (60%), Gaps = 2/264 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAK-PDEITASCHPSDVASAKAFQGLGATALFENXXX 286
+++GFIG G++A ALA GFI K ++ASC +D + + +G N
Sbjct: 5 LRVGFIGAGKMASALAQGFIKGQAVKCASHVSASCPIADKHLLEHMKQMGCQTFHCNKEL 64
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
L +IK+L ++K L +S+A G+ +A ++++L +++++R+M
Sbjct: 65 MDCSDVVILAVKPQIMPLVLPDIKSLVASK--LMVSIAAGVQLAQLQADLNPDSKIVRLM 122
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PNTP +V+EG + F G + T +D QLF VG DEV E +DA+T +SGSGPAY+
Sbjct: 123 PNTPCIVREGVSVFCSGPQVTPQDNATVKQLFGTVGQIDEVKESMIDAVTGVSGSGPAYM 182
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEG 823
Y++IE++ADGGV+ GLPRDLA +LAAQT +G+ MV T HPA+LKD V SP G+T
Sbjct: 183 YLIIEAMADGGVKQGLPRDLAYKLAAQTMVGAGRMVLDTHTHPAVLKDEVCSPGGTTITA 242
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRC 895
LEK+G R++I+ AV AA RC
Sbjct: 243 LDMLEKSGLRTSIMQAVEAATKRC 266
>UniRef50_Q5EI64 Cluster: Pyrroline-5-carboxylate reductase; n=10;
cellular organisms|Rep: Pyrroline-5-carboxylate
reductase - Triticum aestivum (Wheat)
Length = 287
Score = 208 bits (507), Expect = 3e-52
Identities = 115/270 (42%), Positives = 154/270 (57%), Gaps = 1/270 (0%)
Frame = +2
Query: 104 EAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXX 283
+A ++GF+G G LA ++A G ++G+ + + H A AF LGAT L N
Sbjct: 20 DAFRLGFVGAGNLAESIARGVAASGVLPASAVRTAPHRRPERGA-AFASLGATILASNAQ 78
Query: 284 XXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRV 463
L E+K L S + KL +S+A GI + ++ + + R+IRV
Sbjct: 79 VVDGSDVIVISVKPQIVKQVLVELKPLLS-EEKLLVSIAAGIKMKDLQ-DWSGQRRIIRV 136
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
MPNTP+ V + A+ G AT +D LF A+G E DA+T LSGSGPAY
Sbjct: 137 MPNTPSAVGQAASVMCLGETATEKDENRVKSLFSAIGKVWTAEEKYFDAVTGLSGSGPAY 196
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAE 820
+++ IE++ADGGV GLPRDLAL LAAQT LG+A MV +TG HP LKD VTSPAG+T
Sbjct: 197 IFLAIEAMADGGVAAGLPRDLALGLAAQTVLGAATMVSETGKHPGQLKDQVTSPAGTTIA 256
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
G + LEK FR +I AV AA RC+ + K
Sbjct: 257 GVHELEKGSFRGTLINAVVAATTRCRELSK 286
>UniRef50_UPI000058613C Cluster: PREDICTED: similar to
pyrroline-5-carboxylate reductase 1; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyrroline-5-carboxylate reductase 1 - Strongylocentrotus
purpuratus
Length = 276
Score = 204 bits (497), Expect = 5e-51
Identities = 114/278 (41%), Positives = 161/278 (57%), Gaps = 1/278 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
IGF+G G +A L G +SA + I AS PS+ + + LGA N
Sbjct: 6 IGFVGAGNVALTLIKGLLSASAVGAERIMASA-PSN-RNLQVIGDLGAKTTSSNREILET 63
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
+KEI +++LFIS+A GI++ +E+NLP +RV+R MPNT
Sbjct: 64 ADTIFLAIKPNLAGAVIKEIAPFVK-RDQLFISLAAGISLDFIENNLPERSRVVRAMPNT 122
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYML 655
P +++EGA F+ G+ D +L LF +G C E E +DA A+SG GPAY Y+
Sbjct: 123 PTIIREGATVFACGSHIKEGDNRLIQSLFSKLGICIEGDESIIDAAMAVSGCGPAYAYVA 182
Query: 656 IESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYH 832
I++LADGGV+ GLPRD+A++LAAQT LGSA MV + G HP+ LKD+V SP G+T + +
Sbjct: 183 IDALADGGVKMGLPRDIAIKLAAQTLLGSAKMVLRGGKHPSQLKDDVCSPGGTTIDAIHE 242
Query: 833 LEKNGFRSAIIGAVSAAVDRCKIVKKQLNDXTA*LSKK 946
LE+ GFR +I AV AA ++ ++LND +KK
Sbjct: 243 LERGGFRKCLIEAVEAACNKA----RRLNDAMLYSNKK 276
>UniRef50_P32322 Cluster: Pyrroline-5-carboxylate reductase 1; n=61;
Euteleostomi|Rep: Pyrroline-5-carboxylate reductase 1 -
Homo sapiens (Human)
Length = 319
Score = 202 bits (493), Expect = 1e-50
Identities = 113/267 (42%), Positives = 152/267 (56%), Gaps = 4/267 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M +GFIG G+LAFALA GF +AG+ +I AS D+A+ A + +G N
Sbjct: 1 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPS---EARVIR 460
L EI + +S A G+TI+++E L + RVIR
Sbjct: 61 QHSDVLFLAVKPHIIPFILDEI-GADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIR 119
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPA 640
M NTP +V+EGA ++ GT A ED +L QL +VG C EV E +DA+T LSGSGPA
Sbjct: 120 CMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPA 179
Query: 641 YVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTA 817
Y + +++LADGGV+ GLPR LA+RL AQ LG+A M + + HP LKDNV+SP G+T
Sbjct: 180 YAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATI 239
Query: 818 EGTYHLEKNGFRSAIIGAVSAAVDRCK 898
+ LE GFRS +I AV A+ R +
Sbjct: 240 HALHVLESGGFRSLLINAVEASCIRTR 266
>UniRef50_A7SQR3 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 269
Score = 202 bits (492), Expect = 2e-50
Identities = 108/262 (41%), Positives = 160/262 (61%), Gaps = 1/262 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M IGF+G G++A A+A G +++G ++I AS D ++K +GLG N
Sbjct: 1 MSIGFLGAGKMAQAMARGLLASGTFTREQIIASS--IDDITSKEMRGLGIHVTDNNCEAA 58
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L EI + + KN L +S+A G+++ ++E LP ++RV+RVMP
Sbjct: 59 GNKDIVIVAVKPNVVKDVLSEIAPVITPKN-LVVSIAAGVSLKSMEKCLPHKSRVVRVMP 117
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N P LV+ GA+A++ G A +D++ +L AVG ++V E + A+T LSGSGPAY +
Sbjct: 118 NIPTLVRAGASAYALGHNAIGDDSETVKRLMSAVGYVEQVREKDVAAVTGLSGSGPAYCF 177
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGT 826
M IE+LADGGV+ GLPR +A+ LAA T +G+A +V +TG HP LKD+V SP GSTA
Sbjct: 178 MAIEALADGGVKAGLPRQVAINLAAHTLMGAAKLVLETGKHPGELKDSVCSPEGSTAYAI 237
Query: 827 YHLEKNGFRSAIIGAVSAAVDR 892
+ LE+ G R+ ++ AV AA+ R
Sbjct: 238 HSLERAGLRATLMDAVDAALRR 259
>UniRef50_A7HA48 Cluster: Pyrroline-5-carboxylate reductase; n=16;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Anaeromyxobacter sp. Fw109-5
Length = 276
Score = 198 bits (482), Expect = 3e-49
Identities = 110/263 (41%), Positives = 150/263 (57%), Gaps = 1/263 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KI F+G G +A AL G + AG A +EI + P + G + N
Sbjct: 6 KIAFLGSGNMAEALVKGLLGAGTASAEEIVCA-EPRLERREELALRYGVKVIGSNLEATE 64
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L EI + KL +S+A G++IA + L + R++R MPN
Sbjct: 65 QADVVVLSVKPQTMEQLLDEIAPAVDHR-KLVVSIAAGVSIAAIARKLGAGVRIVRTMPN 123
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TPALV GA A +RG AT D + LF+AVGT V E+ +DA+T LSGSGPA++++
Sbjct: 124 TPALVGAGATALARGAHATDWDLEQARSLFQAVGTTVIVEEHHLDAVTGLSGSGPAFLFL 183
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
+IE+LADGGV+ GL R +A+ LAAQT LGSA +V +TG+HP LKD VTSP G+ G +
Sbjct: 184 VIEALADGGVKVGLARSVAMTLAAQTVLGSAKLVLETGEHPGRLKDQVTSPGGTAIAGVH 243
Query: 830 HLEKNGFRSAIIGAVSAAVDRCK 898
LE+ G R+A+I AV AA R +
Sbjct: 244 ALEQGGLRAALIAAVEAATRRSR 266
>UniRef50_Q8GE04 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Heliobacillus mobilis|Rep: Pyrroline-5-carboxylate
reductase - Heliobacillus mobilis
Length = 274
Score = 197 bits (481), Expect = 4e-49
Identities = 114/269 (42%), Positives = 159/269 (59%), Gaps = 2/269 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASC-HPSDVASAKAFQGLGATALFE 274
L+E +IGFIGGG +A AL +G + L P IT S +PS +A ++ + T+ +
Sbjct: 5 LLENRRIGFIGGGAMAEALLSGLVR--LVPPQAITVSDPNPSRLAYLQSEMAVQTTS--D 60
Query: 275 NXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARV 454
N L +K +K+ L IS+A GIT+A +ES L E +
Sbjct: 61 NSVVCEQSDIVVLAVKPQVLPAVLTPLKTAICSKH-LVISIAAGITLAQLESWLSPEVPL 119
Query: 455 IRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSG 634
IRVMPNTPAL+ +GA+A + G + +D Q L +AVG + +PE ++A+T SGSG
Sbjct: 120 IRVMPNTPALIGKGASALAGGRAVSEQDVQTAKALLEAVGIAEVLPETYLNAVTGFSGSG 179
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGS 811
PAYVY+ IE+L D GV+ GL RDLA +LA QT +GSA +++TG+HPA+ +D VTSP G+
Sbjct: 180 PAYVYLFIEALIDAGVKEGLTRDLARKLAIQTVIGSAQLLIETGNHPAIERDKVTSPGGT 239
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
T G LE GFRSA+ AV A R +
Sbjct: 240 TIAGVQALEDGGFRSAVFAAVHAGTKRAR 268
>UniRef50_A6PTF6 Cluster: Pyrroline-5-carboxylate reductase
precursor; n=1; Victivallis vadensis ATCC BAA-548|Rep:
Pyrroline-5-carboxylate reductase precursor -
Victivallis vadensis ATCC BAA-548
Length = 267
Score = 196 bits (478), Expect = 1e-48
Identities = 112/268 (41%), Positives = 153/268 (57%), Gaps = 1/268 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
K+ F+G G++A A+A G + AG + DE+ A + +A+AFQ
Sbjct: 3 KLFFLGAGKMATAIAGGLVKAGTFQADELLA--FDVNPKAAEAFQNATGIRCVTADCKAA 60
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
A A N+LF+S+ G++I + + L R++R+MPN
Sbjct: 61 AAGAETILLAVKPQMLADAAAPLRSEAGNRLFLSIVAGVSIDRL-TELTGSERIVRIMPN 119
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TP LV GAA FS G KA ED LT ++ +VG V E MDA+TALSGSGPAYV+
Sbjct: 120 TPMLVGRGAAGFSAGPKANEEDIALTERILASVGIAFRVDEKYMDAVTALSGSGPAYVFE 179
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
I++LADGGV GLPRD+A +LAAQT LG+A MV KTG HP +LKD VTSPAG+TA
Sbjct: 180 FIQALADGGVSEGLPRDMATQLAAQTVLGAAEMVLKTGTHPTVLKDQVTSPAGTTARALE 239
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+ +NGF + +I A+ A R + + K+
Sbjct: 240 VMYRNGFAATVIDAMHACARRSEELGKK 267
>UniRef50_Q2BA85 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Firmicutes|Rep: Pyrroline-5-carboxylate reductase -
Bacillus sp. NRRL B-14911
Length = 272
Score = 194 bits (473), Expect = 4e-48
Identities = 109/270 (40%), Positives = 160/270 (59%), Gaps = 3/270 (1%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHP-SDVASAKAFQGLGATALFENXXXX 289
KIGFIG G++A A+ G + +G+A+PD+I AS S +A K + T +N
Sbjct: 4 KIGFIGCGKMAQAIIGGMLKSGIARPDDIVASARTESTLAYVKNTYDIEVT--LDNKRAA 61
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
++EI S ++ + I++A GI++A ++S E + IR MP
Sbjct: 62 EQADFLFLAVKPDVHMEVIEEISGSVS-EDAIIITIAAGISLAFLQSAFGREIKAIRSMP 120
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
NTP+LV EG +A + + T ++ ++LF++ G + + E MD+I A+SGS PAYVY
Sbjct: 121 NTPSLVGEGMSALAASRQVTEKERLEAAELFESFGKAEFIEEKLMDSIPAISGSSPAYVY 180
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGT 826
M IE+LADGGV GLPR+ + RLAAQ LG+A MV +TG HP LKD V +P G+T E
Sbjct: 181 MFIEALADGGVLQGLPRETSYRLAAQAVLGAAKMVLETGKHPGELKDQVCTPGGATIEAV 240
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK-IVKKQ 913
LEK GFRS++I A+ + D+ + + KKQ
Sbjct: 241 AELEKQGFRSSVISAMHSCTDKSRQLAKKQ 270
>UniRef50_A5D185 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Pelotomaculum thermopropionicum SI
Length = 273
Score = 193 bits (471), Expect = 7e-48
Identities = 117/270 (43%), Positives = 152/270 (56%), Gaps = 4/270 (1%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKA-FQG--LGATALF 271
++ KIGF+GGG + AL G + GL P I S DV S + + G LG
Sbjct: 3 LKGQKIGFLGGGAMGEALMTGLLRTGLVNPPAICVS----DVNSGRLEYLGKKLGVETHP 58
Query: 272 ENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEAR 451
+N +KEI L L IS+A G+T A +ES L S
Sbjct: 59 KNEAVVRKADIIVMAVKPDAVAHLMKEIAPLLRPGQTL-ISIAAGVTSAFIESFLNSPVP 117
Query: 452 VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGS 631
V+RVMPNTP LV EGA+A S G A E+ + +F A G EVPE +D +T LSGS
Sbjct: 118 VVRVMPNTPCLVGEGASAVSAGKYAGRENMEKALAIFSAAGKAVEVPERLLDCVTGLSGS 177
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAG 808
GPAY+Y+++E L DG VR GLPRD A LAAQT LG+A MV +TG+HPA LKD VT+P G
Sbjct: 178 GPAYMYVILEGLIDGAVRLGLPRDQARLLAAQTMLGAAKMVLETGEHPARLKDMVTTPGG 237
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
+T G + LE+ R+ ++ AV AA +R +
Sbjct: 238 TTIAGLFALEEGAVRALLMKAVEAAAERSR 267
>UniRef50_Q9HH99 Cluster: Pyrroline-5-carboxylate reductase; n=5;
cellular organisms|Rep: Pyrroline-5-carboxylate
reductase - Methanosarcina acetivorans
Length = 270
Score = 193 bits (471), Expect = 7e-48
Identities = 117/275 (42%), Positives = 158/275 (57%), Gaps = 4/275 (1%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASA--KAFQG-LGATALF 271
+E KIGFIG G++ AL G I AG+ P+ I AS DV K Q LG
Sbjct: 1 MENQKIGFIGAGKMGSALMQGTIKAGIVTPENIGAS----DVYEPFLKDLQAKLGIRVST 56
Query: 272 ENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEAR 451
+N L +KN +++ KL IS+A G+ ++T E L R
Sbjct: 57 DNAVIVRESDILILAVKPQTLSSVLSNLKNEITSE-KLVISIAAGVPLSTYEDALLEGTR 115
Query: 452 VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGS 631
V+RVMPN A V E A+ + G AT ED + ++F AVGT +VPE MDA+T LSGS
Sbjct: 116 VVRVMPNIAATVSEAASGIAPGKNATPEDLKAALEIFSAVGTAVQVPESLMDAVTGLSGS 175
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAG 808
GPA+++ +IE++ADG V G+ R AL LAAQT LG+A M ++TG HP LKD VTSPAG
Sbjct: 176 GPAFIFPVIEAMADGAVLEGMDRKSALTLAAQTVLGAAKMALETGMHPGELKDMVTSPAG 235
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+T +G + LE+ G R+A + AV A +R K + K+
Sbjct: 236 TTIQGIHSLEEAGIRAAFMNAVIRASERSKELGKK 270
>UniRef50_A7RN43 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 276
Score = 193 bits (470), Expect = 9e-48
Identities = 114/278 (41%), Positives = 165/278 (59%), Gaps = 2/278 (0%)
Frame = +2
Query: 92 LPLIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALF 271
+ LI +M GFIG G+ A A+A GF+SAG+ K +I AS P D + + F+ LG T
Sbjct: 1 MSLISSM--GFIGAGKAATAMAKGFLSAGVIKASDIIASA-PRD-SDLRNFRALGCTVTS 56
Query: 272 ENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEAR 451
+N ++EI + + ++ + S+A G+T+ ++ +LP R
Sbjct: 57 DNKKVIKEAKTIFLATKAKAFPQVMQEISPVVT-RDHIVSSIAAGVTLEWLQKSLPGRTR 115
Query: 452 VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGS 631
+IR+M NTP +EG A + G A ED + +L +VG C EV E MD +TAL+G
Sbjct: 116 LIRMMLNTPVQFREGVTAMTFGKFAREEDYKDIHELMSSVGYCFEVDEDLMDVMTALTGG 175
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAG 808
GPAY+Y+ IE++ADG VR GL R+ A++LAA+T G+A MV ++G HP LKD V S G
Sbjct: 176 GPAYLYLAIEAMADGAVRAGLNREQAMKLAAKTASGAARMVLESGLHPGELKDQVCSAGG 235
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAVDRCKIV-KKQLN 919
ST G + LE++GFR A++ AV+AA R K V K +LN
Sbjct: 236 STIAGIFALEESGFRGALMKAVAAASLRAKEVGKGELN 273
>UniRef50_Q00XH4 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Ostreococcus|Rep: Pyrroline-5-carboxylate reductase -
Ostreococcus tauri
Length = 282
Score = 192 bits (467), Expect = 2e-47
Identities = 107/269 (39%), Positives = 157/269 (58%), Gaps = 8/269 (2%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M++GFIG G +A ALA+GF+ A + K ++T C+ S+V ++F+ G T +
Sbjct: 8 MRVGFIGYGNMADALASGFVGANVVKFADLTM-CNKSNVERRESFRARGGTVVETARDVT 66
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKN---KLFISVAMGITIATVESNLPSEAR--- 451
L E++ S + K+F+SVA G+T+ +E + +
Sbjct: 67 EKSDVIFLAVKPPYIKSVLDEVRREISEEALEPKVFVSVAAGVTLEAMEGVWTTHDQKPP 126
Query: 452 -VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSG 628
++RVMPNTP LV A+ +G+ + E L VG C + E QM A+T +SG
Sbjct: 127 AIVRVMPNTPCLVGAAASGICKGSTCSEESLHRALALMSTVGVCKVIMESQMSALTGVSG 186
Query: 629 SGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPA 805
SGPAYV++LIE++ADGGVR GLPRD+AL LAAQT G++ MV +TG+HP +LKD V SP
Sbjct: 187 SGPAYVFVLIEAMADGGVRAGLPRDVALELAAQTFYGASKMVLETGEHPGVLKDKVCSPG 246
Query: 806 GSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
G+T + LE+ G R+A++ AV AA +R
Sbjct: 247 GTTIAAVHALEQAGVRAAMMNAVLAAANR 275
>UniRef50_A7SC14 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 274
Score = 192 bits (467), Expect = 2e-47
Identities = 109/270 (40%), Positives = 154/270 (57%), Gaps = 1/270 (0%)
Frame = +2
Query: 107 AMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXX 286
++ +GFIGGG +A ALA GFIS+ + K + I AS + ++ +G +N
Sbjct: 8 SLHVGFIGGGNMAIALAKGFISSKMVKSENIIASALTERTLTH--WKEIGCKTTLKNSDV 65
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
+KEI L + ++ L +SVA GI +++ RVIR+M
Sbjct: 66 VAHSAVLFIAVKPHLVPTVMKEIDKLITERH-LVVSVAAGIPLSSFSK--VGSIRVIRLM 122
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PN P VK+GAAAFS G KAT EDA L QL G EV E +D + ++GSG A+V
Sbjct: 123 PNLPCSVKQGAAAFSCGEKATREDADLVHQLISTTGFVAEVKEPLIDTVCGVAGSGSAFV 182
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEG 823
Y++IE++ADG V+ GLPR LA + A Q LG+A VK +G HPA LKD SP G+T +G
Sbjct: 183 YVVIEAMADGAVKAGLPRVLANQFATQAVLGAATYVKESGKHPAQLKDETCSPGGTTIDG 242
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
Y LE+ G R+A I AV++A + + + K+
Sbjct: 243 IYQLERGGVRAAFIDAVTSAASKAQELGKK 272
>UniRef50_A0WB61 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Geobacter lovleyi SZ|Rep: Pyrroline-5-carboxylate
reductase - Geobacter lovleyi SZ
Length = 273
Score = 185 bits (450), Expect = 2e-45
Identities = 107/262 (40%), Positives = 146/262 (55%), Gaps = 1/262 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
+GFIGGG +A A+ G IS G+A P I S P A L EN
Sbjct: 7 VGFIGGGNMAEAIIKGLISGGMA-PRNIIVS-DPVQDRRALLASTLSVRTTDENSEVAQQ 64
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
L ++N +A+ +L +S+ GI+ +E +L + RV+R MPNT
Sbjct: 65 AELIVLSIKPQMAASVLTALENTITAQ-QLVLSIMAGISTTIIEESLQNGVRVVRAMPNT 123
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYML 655
PALV+ GA A G +A D L +LF VGT +V E QMDA+T +SGSGPAYV+
Sbjct: 124 PALVQAGATAICGGRRAGEADLALAKELFSLVGTVYQVGERQMDAVTGVSGSGPAYVFSF 183
Query: 656 IESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYH 832
IE+L+D GV+ GLPRD+A LA QT LGSA ++ ++ +HPA+L+D V+SP G+T +
Sbjct: 184 IEALSDAGVKNGLPRDVATGLAVQTVLGSAQLLQQSNEHPAVLRDRVSSPGGTTIAALHT 243
Query: 833 LEKNGFRSAIIGAVSAAVDRCK 898
LE ++ AV AAV R K
Sbjct: 244 LENGRLHGLLMDAVDAAVKRSK 265
>UniRef50_Q6NP47 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Endopterygota|Rep: Pyrroline-5-carboxylate reductase -
Drosophila melanogaster (Fruit fly)
Length = 341
Score = 183 bits (445), Expect = 1e-44
Identities = 100/269 (37%), Positives = 152/269 (56%), Gaps = 9/269 (3%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KIGFIGGG +A+A+ +G + G+ K ++ S + + + ++ LGA +N
Sbjct: 68 KIGFIGGGNMAYAIGSGLVRCGIVKASQVQVS--GPHIENLQRWRDLGAVTCDDNCMVLE 125
Query: 293 XXXXXXXXXXXXXXXPALKEIK--NLPSAKN--KLFISVAMGITIATVESNLP----SEA 448
P ++K ++PSAK+ KL +SV G ++ T+E SE
Sbjct: 126 HSDIVFICVKPHMLTPCAAQLKYKHVPSAKDASKLVVSVLAGTSLETLEEAFSFMGSSEL 185
Query: 449 RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSG 628
+VIR MPNT V EG ++ + + D + + A+G +VPE +DA+T ++G
Sbjct: 186 KVIRTMPNTSMQVGEGCTVYTGNARVSHHDLEKIHLMLNALGLAQQVPESMIDAVTGVAG 245
Query: 629 SGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPA 805
GPA+VY +IE+LADGGV+ G+PR +AL+ AAQT LG+A ++ TG HPA+L+D V SP
Sbjct: 246 CGPAFVYTIIEALADGGVKQGVPRQMALQFAAQTLLGAAKTVLLTGKHPAVLRDEVCSPG 305
Query: 806 GSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
G+T G + LEK RS +I AV + R
Sbjct: 306 GATIVGVHELEKGNLRSTLINAVEKSSQR 334
>UniRef50_UPI00015B577C Cluster: PREDICTED: similar to GA19292-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19292-PA - Nasonia vitripennis
Length = 282
Score = 177 bits (431), Expect = 5e-43
Identities = 98/263 (37%), Positives = 143/263 (54%), Gaps = 4/263 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
+GF+GGG +A A+ G + G+ KP+ I S S ++ +G F N
Sbjct: 12 VGFVGGGNMAQAIGLGLVKKGVIKPNNIWVSSRTEKTLSV--WESVGINITFNNYEVVQN 69
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNL---PSEARVIRVM 466
AL+ K KLF+SV +GI + T++ L S ++IR M
Sbjct: 70 SDVIFLAVKPQMLDEALRTCKPPHHTTGKLFVSVIVGIPLDTLDEKLRAVDSFPKIIRSM 129
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
P+TP +V EG + + E+ + LF +G C+++PE M++ LSGSGPAY
Sbjct: 130 PSTPMMVGEGITVYC-SLRTNEEEECAINYLFSQLGLCEKIPESLMNSAGGLSGSGPAYA 188
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEG 823
YM+IE+LADG V+ G+PR A R AAQ +G+ MV +TG HP +LKD V SP GST G
Sbjct: 189 YMIIEALADGAVKKGIPRASATRFAAQVLVGAGKMVLETGKHPGLLKDEVCSPGGSTITG 248
Query: 824 TYHLEKNGFRSAIIGAVSAAVDR 892
+ +E G R+A++ AV AAV++
Sbjct: 249 VHAMETGGVRAAMMNAVEAAVNK 271
>UniRef50_UPI000051A719 Cluster: PREDICTED: similar to Pyrroline
5-carboyxlate reductase CG6009-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pyrroline
5-carboyxlate reductase CG6009-PA - Apis mellifera
Length = 281
Score = 176 bits (428), Expect = 1e-42
Identities = 101/264 (38%), Positives = 144/264 (54%), Gaps = 6/264 (2%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
K+GFIGGG +A A+ G I G+ PD + S + + LGA A +N
Sbjct: 10 KVGFIGGGNMASAIGAGLIRKGILNPDNVWVSARTNKTLGF--WNDLGAHATLKNGEVVD 67
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNK--LFISVAMGITIATVESNLPSEA---RVI 457
ALK I+ ++K LF+SV +G+T+ + + L S R+I
Sbjct: 68 NCDIIFLAMKPHMFDDALKGIRETMTSKASHILFVSVLVGVTLDCLANKLKSIVTYPRII 127
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGP 637
R MPNTP +V EG + T +D + +LF +G + VPE M+AI LSGSGP
Sbjct: 128 RCMPNTPMMVGEGITVYC-SMNTTNQDETIIEKLFSYIGVIENVPESLMNAIGGLSGSGP 186
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGST 814
AY Y++IE+LADG V+ G+PR +A + AAQ +G+ MV +TG HP LKD V SP G+T
Sbjct: 187 AYAYLVIEALADGAVKMGVPRPMATKFAAQVLVGAGKMVLETGRHPGQLKDEVCSPGGTT 246
Query: 815 AEGTYHLEKNGFRSAIIGAVSAAV 886
G + +E R++++ AV AAV
Sbjct: 247 ITGVHAMECGQVRASMMNAVEAAV 270
>UniRef50_A5N0V3 Cluster: ProC2; n=1; Clostridium kluyveri DSM
555|Rep: ProC2 - Clostridium kluyveri DSM 555
Length = 283
Score = 175 bits (425), Expect = 3e-42
Identities = 112/278 (40%), Positives = 152/278 (54%), Gaps = 8/278 (2%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KIGFIG G++ A+ G ++ L +PD+I D + G L +
Sbjct: 7 KIGFIGTGQMGEAILKGLLTTELFEPDDIYVM-DVLDSRLQYLKENFGIAHLSSDRSTAY 65
Query: 293 XXXXXXXXXXXXXXXP-ALKE----IKNLPSAKNK-LFISVAMGITIATVESNLPSEARV 454
P LK+ IK+ K K IS+ GI + +E +LP E V
Sbjct: 66 NYIVDNCDIVVLSIKPQVLKDVVECIKSCNWDKEKHTVISIIGGINTSLIEKHLP-EIPV 124
Query: 455 IRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSG 634
+RVMPNTP LV GA+ + G A+ E A+L +F+A+G V E +D+ITA+SG G
Sbjct: 125 VRVMPNTPMLVNIGASGVAPGKNASKEHAKLVYGMFEALGVSYLVEEKYIDSITAISGCG 184
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGS 811
PAYVYM+IE++ADGGV GLPR++A LAAQT +G A M+ TG+HP LKD V SP GS
Sbjct: 185 PAYVYMMIEAMADGGVELGLPREMAQTLAAQTVMGGAKMILDTGEHPGKLKDKVCSPGGS 244
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDRCKIV-KKQLND 922
T G LE+ FR I+ A+ A R + V KK+ N+
Sbjct: 245 TIAGVRALERGAFRGTIMNAIEAGKVRMEEVGKKEENN 282
>UniRef50_Q97E64 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Clostridium|Rep: Pyrroline-5-carboxylate reductase -
Clostridium acetobutylicum
Length = 270
Score = 174 bits (424), Expect = 3e-42
Identities = 95/269 (35%), Positives = 151/269 (56%), Gaps = 2/269 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
K+GFIG G +A A+ G + A + + I S +PS+ K + G +N
Sbjct: 4 KVGFIGCGNMAQAIIKGMVKAKVVPNENIIVS-NPSNEKLEKISKECGVLTTNDNKQVAL 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLP-SEARVIRVMP 469
+ EIK+L ++ + +++A G++I S RV+R MP
Sbjct: 63 KADIIVLSVKPNKYEKVISEIKDLVQ-QSVIIVAIAAGVSIEKTRIMFKNSNIRVVRAMP 121
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
NTPALV E A S + + + +++F++ G C+ V E M+A+T +SGS PAYVY
Sbjct: 122 NTPALVGEAMTAISPCEEIDKGELKNVTEIFESFGKCEVVDEALMNAVTGVSGSSPAYVY 181
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGT 826
M +E++AD V G+ R+ A + AAQ+ LG+A M+ +TG+HP LKD+V SP+G+T E
Sbjct: 182 MFVEAMADAAVLNGMTREKAYKFAAQSVLGAAKMILETGEHPGKLKDDVCSPSGTTIEAV 241
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
Y LEK+GFR+++I AV A + + K++ +
Sbjct: 242 YALEKSGFRASVIAAVDACIKKSKLMSSK 270
>UniRef50_Q1IRM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Acidobacteria bacterium Ellin345|Rep:
Pyrroline-5-carboxylate reductase - Acidobacteria
bacterium (strain Ellin345)
Length = 280
Score = 174 bits (424), Expect = 3e-42
Identities = 99/262 (37%), Positives = 139/262 (53%), Gaps = 1/262 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
+ +G G++ L + GL P + A+ + +D +AK Q G +N
Sbjct: 16 VAILGLGKIGSILLQAMLREGLLSPKRVRATVNHAD-KTAKLTQEFGIQVGTDNAAAIKG 74
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
L +++ N+L ISVA + A +E L ++ +IR MPNT
Sbjct: 75 ADIILVALKPQQIGTVLTSLRD-EIKPNQLLISVAASVPTAYMEERLAAKVPIIRAMPNT 133
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYML 655
P+++ G +G ATA L +F VG V E MDA+T LS SGPA++Y++
Sbjct: 134 PSMLGAGMTGICKGAHATAAQLDLAQAMFNTVGRTAIVEEKHMDAVTGLSASGPAFIYII 193
Query: 656 IESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYH 832
IESLA+ GV+ GLPRDLA LAAQTT+G+A +V +TG HPA LKD VT+PAG T +G
Sbjct: 194 IESLAEAGVKVGLPRDLATLLAAQTTMGAAQVVLETGQHPAQLKDAVTTPAGCTIDGILE 253
Query: 833 LEKNGFRSAIIGAVSAAVDRCK 898
LE+ R +I AV A R K
Sbjct: 254 LEEGKLRVTLIKAVVKAAQRAK 275
>UniRef50_Q4SMN2 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Clupeocephala|Rep: Pyrroline-5-carboxylate reductase -
Tetraodon nigroviridis (Green puffer)
Length = 333
Score = 174 bits (423), Expect = 4e-42
Identities = 100/264 (37%), Positives = 145/264 (54%), Gaps = 1/264 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
+KIGFIG G +AF + G +S + P + S PS V + FQ LG N
Sbjct: 71 LKIGFIGAGNMAFGITKGIMSGNIL-PGNVKVSA-PS-VRNLGRFQELGVPVTHSNAEVV 127
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L EI + ++ + +SVA G+T+AT+E LP VIR+MP
Sbjct: 128 RGSDVVFVAVKPHLVPHVLGEISQHVTDRH-VIVSVAAGVTLATLEELLPENTVVIRMMP 186
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N P LV+EGA F+RG+ A ED L L G +E PE +D T +SGSG A+VY
Sbjct: 187 NLPCLVQEGALLFARGSHAKPEDGALLRSLLHHCGLVEEGPELWIDIHTGMSGSGVAFVY 246
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGT 826
+ E+LA+G V+ G+P LA +A+QT LG+ +++ +G HPA L+ V +P G+T G
Sbjct: 247 LFAEALAEGAVKMGMPSALAHSIASQTVLGAGRVLRDSGKHPAQLRAEVCTPGGTTIYGL 306
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK 898
+ LE+ G R+A + AV +A +R +
Sbjct: 307 HTLEQGGVRAATMSAVESATERAR 330
>UniRef50_UPI0000D556D2 Cluster: PREDICTED: similar to CG6009-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG6009-PA - Tribolium castaneum
Length = 309
Score = 173 bits (420), Expect = 1e-41
Identities = 101/272 (37%), Positives = 146/272 (53%), Gaps = 6/272 (2%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KIGFIG G +A AL GL ++ S + + ++ LGA +N
Sbjct: 40 KIGFIGDGNMAKALCKSIERRGLINYSQVYVSS--PYIKNLNVWKELGANTTTDNTEVAQ 97
Query: 293 XXXXXXXXXXXXXXXPAL-KEIKNLPSA--KNKLFISVAMGITIATVESNLP--SEARVI 457
L K IK+ ++ NKLF+S+ GIT+ +E +RVI
Sbjct: 98 KSDIVFLAVKPHMLGEILDKIIKDATASPISNKLFVSILAGITLRELEEKTKVFQGSRVI 157
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGP 637
RVMPNTP +V EG A+ G T ED + + + G+C +PE ++A+ A+S SGP
Sbjct: 158 RVMPNTPVVVGEGYTAYCPGQNVTEEDLSIIKSILEVTGSCQLLPEKMINAVGAISSSGP 217
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGST 814
A+VY+ IE+L+DGGVR GL R+++ ++AAQT +G+A MV +T H LKD V S G+T
Sbjct: 218 AFVYLFIEALSDGGVRMGLHREMSTKIAAQTVMGAAKMVLETSKHMGTLKDEVCSAGGTT 277
Query: 815 AEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
G + LEK G R +++ AV AA R + K
Sbjct: 278 IAGVHELEKGGVRGSVMNAVEAAAKRADELAK 309
>UniRef50_A6TR68 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Alkaliphilus metalliredigens QYMF|Rep:
Pyrroline-5-carboxylate reductase - Alkaliphilus
metalliredigens QYMF
Length = 281
Score = 173 bits (420), Expect = 1e-41
Identities = 99/267 (37%), Positives = 141/267 (52%), Gaps = 5/267 (1%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGL----GATALFENX 280
+IGFIG G +A A+ G + + + I+ + P+ + L N
Sbjct: 4 RIGFIGTGNMATAIVQGLVKDYVGMENYISVNNRPTTQDKMSKAESLHKKFNVNLEASNL 63
Query: 281 XXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIR 460
L+EI+ ++++ + +SVA G++IA +E +VIR
Sbjct: 64 DIVKKSKIIFLTVKPNIYPKVLEEIREFITSEH-VIVSVAAGVSIALIEGFFDKPVKVIR 122
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPA 640
MPNTP V EG A + T ++ + ++F ++G + + E MDAI A+SGS PA
Sbjct: 123 TMPNTPVFVGEGMTAVTPNNYVTDDELRTVVEIFSSMGEVEIIGEGIMDAIPAISGSSPA 182
Query: 641 YVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTA 817
YVY IE+LADGGV G+PRD A + AAQ G+A MV ++ +HP +LKD V SPAGST
Sbjct: 183 YVYTFIEALADGGVSLGIPRDKAYKFAAQAVYGAAKMVLESNEHPGVLKDQVCSPAGSTI 242
Query: 818 EGTYHLEKNGFRSAIIGAVSAAVDRCK 898
E Y LEKNGFR II A+ A R K
Sbjct: 243 EALYVLEKNGFRGTIIEAMKACTHRAK 269
>UniRef50_Q8RA68 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Thermoanaerobacter|Rep: Pyrroline-5-carboxylate
reductase - Thermoanaerobacter tengcongensis
Length = 264
Score = 172 bits (418), Expect = 2e-41
Identities = 101/267 (37%), Positives = 143/267 (53%), Gaps = 1/267 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKIGFIG G + AL G + + + +++ P + G +N
Sbjct: 1 MKIGFIGAGNMGMALIKGILKSDFVEAEDLILY-DPVREKVEGLEREFGTVTAKDNLELT 59
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
LKEI+ + + K+ I++A GITI V+ L +++R +P
Sbjct: 60 EKSDVVIVAVKPNVYDEVLKEIREKVT-EEKIIITIAPGITIDHVKKLL-GRGKIVRTIP 117
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
NTPAL+ EG A + + ED +L ++F G E+ E +D A+S PA+VY
Sbjct: 118 NTPALIGEGITAVTYSEEVKEEDKELVRKIFSTCGEIVEIEEKLIDVAMAVSSCSPAFVY 177
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGT 826
M IE+LADGGV GLPRD+A +LA++ G+ +MV KTG HP LKD VTSP G+T EG
Sbjct: 178 MFIEALADGGVLLGLPRDVAYKLASKAVSGAGSMVFKTGFHPGQLKDMVTSPGGTTIEGI 237
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVK 907
LEK+G RSA+I AV AA + K +K
Sbjct: 238 RVLEKSGMRSAVIEAVIAAYQKAKGLK 264
>UniRef50_A4M789 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Petrotoga mobilis SJ95
Length = 274
Score = 172 bits (418), Expect = 2e-41
Identities = 102/268 (38%), Positives = 145/268 (54%), Gaps = 1/268 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
K+ IG G++ L G I K ++I + + S K + +N
Sbjct: 4 KLCVIGLGKMGSTLVKGLIQTKTLKREQIIGT-DLFEYDSEKNSNYSDIKTISDNAKAVK 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L+EI + S +NK+ IS+A G+++ ++ LP+ +++IR MPN
Sbjct: 63 ESDIVLLAVKPQVIDKVLEEISS--SCENKIVISIAAGVSLRHLDKALPTSSKIIRAMPN 120
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TP LV EG A S+ D + ++ ++VG V E MDAITALSGSGPAYVYM
Sbjct: 121 TPILVGEGVIAISKKKNVDENDLKRVKEILESVGKVYLVEEDIMDAITALSGSGPAYVYM 180
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
+IE+L+DGGV GLPR+L+ AA+T LG+A MV +TG HP LKD VTSP G+ +G
Sbjct: 181 MIEALSDGGVLMGLPRELSTEFAARTLLGAARMVLETGKHPGELKDMVTSPGGTAIKGIE 240
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
LE +G R ++ AV A R K + Q
Sbjct: 241 VLESHGLRGILMDAVKEATIRSKELNSQ 268
>UniRef50_Q7UTG7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Pirellula sp.|Rep: Pyrroline-5-carboxylate reductase -
Rhodopirellula baltica
Length = 276
Score = 171 bits (415), Expect = 4e-41
Identities = 101/262 (38%), Positives = 139/262 (53%), Gaps = 4/262 (1%)
Frame = +2
Query: 125 IGGGRLAFALANGFISAGLAKPDEITASCHPSDVA---SAKAFQGLGATALFENXXXXXX 295
IGGG++A AL G + +G K E+T S+K + T E
Sbjct: 13 IGGGQMARALVGGMLESGCLKASELTIVHKTKSTGEWWSSKYSECTTTTDTVEAVAGAKV 72
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
KL +S+A GI + + + + RV+RVMPNT
Sbjct: 73 VMLAVKPHIIAEVLAVKNSAGKSADWSGKLIVSIAAGIGLDKLIDGVGHD-RVVRVMPNT 131
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYML 655
P+LV EGA+ F + +D QL + +VG +V E QM+ +T +SGSGPAYV+++
Sbjct: 132 PSLVGEGASGFCVSGGVSDDDVQLIETMLNSVGIAAQVTEPQMNGVTGVSGSGPAYVFLI 191
Query: 656 IESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYH 832
IE+LADGGV GLPR AL+LA QT LG+A MV+ TG+HP LKDNV SP G+T
Sbjct: 192 IEALADGGVAAGLPRATALQLATQTVLGAAKMVRETGEHPGFLKDNVCSPGGTTIAAMSV 251
Query: 833 LEKNGFRSAIIGAVSAAVDRCK 898
LE+N R A+I AV A+ +R +
Sbjct: 252 LEQNAVRGAMIQAVQASANRSR 273
>UniRef50_P74572 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Synechocystis sp. (strain PCC 6803)
Length = 267
Score = 167 bits (405), Expect = 7e-40
Identities = 88/182 (48%), Positives = 114/182 (62%), Gaps = 1/182 (0%)
Frame = +2
Query: 371 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 550
A L IS+ G+++ ++ P A +IR MPNTPA V G A + +
Sbjct: 87 ANRPLVISILAGVSLQRIQKGFPDHA-IIRAMPNTPATVGAGMTAIAANKMVEPDQLAKA 145
Query: 551 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 730
+F AVG EVPE MDA+T +SGSGPAYV ++IE+LADGGV GLPR +A +LA QT
Sbjct: 146 KAIFSAVGNVVEVPENLMDAVTGVSGSGPAYVALMIEALADGGVLAGLPRAIAQKLALQT 205
Query: 731 TLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 907
LG+A ++K T +HPA +KD VTSP G+T G LEK GFRSAII AV AA R + +
Sbjct: 206 VLGTAELIKETEEHPAQIKDKVTSPGGTTIAGVAVLEKMGFRSAIIEAVRAAYRRSQELG 265
Query: 908 KQ 913
K+
Sbjct: 266 KK 267
>UniRef50_UPI00015C417B Cluster: pyrroline-5-carboxylate reductase;
n=1; Streptococcus gordonii str. Challis substr.
CH1|Rep: pyrroline-5-carboxylate reductase -
Streptococcus gordonii str. Challis substr. CH1
Length = 268
Score = 166 bits (404), Expect = 9e-40
Identities = 84/178 (47%), Positives = 115/178 (64%), Gaps = 1/178 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L +S+A G+T+ +E PS R IR+MPNTP +V EG +F+ +A D L +L
Sbjct: 90 LLVSMAAGLTLELLEKLTPSHHRWIRIMPNTPVVVGEGVISFALSQQANQTDEDLLQELL 149
Query: 563 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
+ G + E Q+DA TAL+G GPA+VY+ IE+LAD GVR GL RD++L LA QT LG+
Sbjct: 150 SSAGLLVRLEEKQLDAATALAGCGPAFVYLFIEALADAGVRAGLSRDISLELANQTLLGA 209
Query: 743 AAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
A + + +G HPA LKD+V SPAGST G LE+N FR ++ AV AA + K + K+
Sbjct: 210 AKLSQVSGQHPAQLKDHVCSPAGSTIAGVASLEENAFRGTVMDAVQAAYKKTKELGKK 267
>UniRef50_Q53H96 Cluster: Pyrroline-5-carboxylate reductase-like
protein; n=27; Euteleostomi|Rep: Pyrroline-5-carboxylate
reductase-like protein - Homo sapiens (Human)
Length = 276
Score = 166 bits (404), Expect = 9e-40
Identities = 92/242 (38%), Positives = 135/242 (55%), Gaps = 1/242 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
++GF+G GR+A A+A G I AG + I AS P+D + FQ LG N
Sbjct: 22 RVGFVGAGRMAGAIAQGLIRAGKVEAQHILASA-PTD-RNLCHFQALGCRTTHSNQEVLQ 79
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L E+ + + ++ + +SVA G++++T+E LP RV+RV+PN
Sbjct: 80 SCLLVIFATKPHVLPAVLAEVAPVVTTEH-ILVSVAAGVSLSTLEELLPPNTRVLRVLPN 138
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
P +V+EGA +RG + + L L +A G C+EVPE +D T LSGSG A+V
Sbjct: 139 LPCVVQEGAIVMARGRHVGSSETNLLQHLLEACGRCEEVPEAYVDIHTGLSGSGVAFVCA 198
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTY 829
E+LA+G V+ G+P LA R+AAQT LG+A M + G HPA L+ +V +P G+T G +
Sbjct: 199 FSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGLH 258
Query: 830 HL 835
L
Sbjct: 259 AL 260
>UniRef50_Q9X8G1 Cluster: Pyrroline-5-carboxylate reductase; n=11;
Actinomycetales|Rep: Pyrroline-5-carboxylate reductase -
Streptomyces coelicolor
Length = 284
Score = 166 bits (403), Expect = 1e-39
Identities = 100/264 (37%), Positives = 141/264 (53%), Gaps = 2/264 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
K+ +G G++ AL +G I AG A D + + +A G+ N
Sbjct: 18 KVAVLGTGKIGEALLSGMIGAGWAPADLLVTARRRERADELRARHGVTPVT---NAEAAK 74
Query: 293 XXXXXXXXXXXXXXXPALKEIK-NLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L E+ ++P+ ++L IS A G+ + E L V+RVM
Sbjct: 75 AADTLILTVKPQDMGTLLDELAPHVPA--DRLVISGAAGVPTSFFEERLAPGTPVVRVMT 132
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
NTPALV E + S GT ATA T ++F AVG VPE Q DA TALSGSGPAY +
Sbjct: 133 NTPALVDEAMSVISAGTHATAAHLTHTEEIFGAVGKTLRVPESQQDACTALSGSGPAYFF 192
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGT 826
L+E++ D G+ GLPRD A L Q+ +G+A M++ +G+HP L++NVTSPAG+T
Sbjct: 193 YLVEAMTDAGILLGLPRDKAHDLIVQSAIGAAKMLRDSGEHPVKLRENVTSPAGTTINAI 252
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK 898
LE +G R+A+I A+ AA DR +
Sbjct: 253 RELENHGVRAALIAALEAARDRSR 276
>UniRef50_Q6NJK7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Corynebacterium diphtheriae|Rep: Pyrroline-5-carboxylate
reductase - Corynebacterium diphtheriae
Length = 270
Score = 161 bits (391), Expect = 3e-38
Identities = 91/261 (34%), Positives = 148/261 (56%), Gaps = 2/261 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I IGGG++ AL +G +++G++ P +I + ++ A + + G EN
Sbjct: 7 IAVIGGGKIGEALISGLVASGMS-PKDIHVTNRNAERAQ-ELKERYGVLTFLENIAAVDD 64
Query: 296 XXXXXXXXXXXXXXPALKEIKNL-PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
P ++EI ++ + + +S+A G+T A +E +L + + VIRVMPN
Sbjct: 65 VDMVFLCVKPQQVIPVVEEIADVVDNNTSTTIVSMAAGVTNAMIEESLAAGSPVIRVMPN 124
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TP LV +G + + G A + +QL +AVG+ + + E MDA+ ALSGS PAY+++
Sbjct: 125 TPMLVGKGMSVVAPGRYADEDTVASLTQLLEAVGSVEVIEESSMDAVVALSGSSPAYLFL 184
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
++E+L D GV GLPRD A LA + G+A M+ +TG+ PA+L+ NV+SP G+T
Sbjct: 185 MVEALIDAGVFLGLPRDKAKNLAVSSFAGAATMLEQTGEEPAVLRANVSSPGGTTIAAIR 244
Query: 830 HLEKNGFRSAIIGAVSAAVDR 892
E++G R+A+ A +AA R
Sbjct: 245 EFEESGLRAAVYRAATAAATR 265
>UniRef50_A6G2U4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Plesiocystis pacifica SIR-1|Rep: Pyrroline-5-carboxylate
reductase - Plesiocystis pacifica SIR-1
Length = 267
Score = 161 bits (391), Expect = 3e-38
Identities = 95/258 (36%), Positives = 135/258 (52%), Gaps = 5/258 (1%)
Frame = +2
Query: 125 IGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXXX 304
IG G + A+ G + AG +PD + + + VA + + LG A +N
Sbjct: 4 IGCGTMGEAIVGGLMRAGWLEPDRVVVTARRASVAE-RLHERLGVAATTDNLAACQGAQV 62
Query: 305 XXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPAL 484
L + KL IS+A G+T++++ LP A +IR MPNTP L
Sbjct: 63 VLVCLKPQRFAKILDNDAMREALAGKLLISIAAGVTLSSLAQWLPQTA-LIRAMPNTPCL 121
Query: 485 VKEGAAAFSRG----TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
+ EG R T A+ E L ++F +VG EV MDA+T+L+GSGPA+VY+
Sbjct: 122 IGEGMTVLGRRDAGPTAASDEQLALAKRIFDSVGVTAEVEPKLMDAVTSLNGSGPAFVYV 181
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTY 829
++E++ADGGV GLPRD+A+ +AAQ G+A MV D HPA LKD VT+PAG T G
Sbjct: 182 MLEAMADGGVMMGLPRDVAVTIAAQVFRGAAGMVLDTDLHPAALKDQVTTPAGCTIAGIL 241
Query: 830 HLEKNGFRSAIIGAVSAA 883
+E RS + + A
Sbjct: 242 TMEDGRIRSVLARTIQEA 259
>UniRef50_Q8KG91 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Chlorobiaceae|Rep: Pyrroline-5-carboxylate reductase -
Chlorobium tepidum
Length = 266
Score = 161 bits (390), Expect = 4e-38
Identities = 103/270 (38%), Positives = 141/270 (52%), Gaps = 3/270 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCH--PSDVASAKAFQGLGATALFENXX 283
+ IGFIG GR+A AL +G P+ + P + S G+ E+
Sbjct: 4 LSIGFIGTGRIAQALISGLSH----DPNIVICGYDKMPDALHSVSLQYGVNTEESIESLA 59
Query: 284 XXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRV 463
L E+K ++ L +SVA GI+ +ESN P RV+RV
Sbjct: 60 RDAEIIVIAVKPYQMAE--VLAELKPALHGQH-LIVSVAAGISTGFIESNCPEGTRVVRV 116
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
MPNTPA V EG A +G ATA+D + ++F A+G + E MDA TA+SGSGPAY
Sbjct: 117 MPNTPAFVGEGMTALCKGMHATADDLLVAERIFNAIGKTAIIEESGMDAATAVSGSGPAY 176
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGSTAE 820
++ +I+SLA+GG CGL R+ A LAAQT LG+A MV +G P L VT+P G+T
Sbjct: 177 MFRIIDSLAEGGEACGLDRETAQLLAAQTMLGAAKMVLSGHKSPEELVREVTTPGGTTEA 236
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
G +++ R A+I V AA R K + K
Sbjct: 237 GLKAMDERDLRGALIDTVRAAAARSKELMK 266
>UniRef50_Q97R93 Cluster: Pyrroline-5-carboxylate reductase; n=13;
Streptococcus|Rep: Pyrroline-5-carboxylate reductase -
Streptococcus pneumoniae
Length = 265
Score = 160 bits (389), Expect = 6e-38
Identities = 97/269 (36%), Positives = 143/269 (53%), Gaps = 2/269 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKIGFIG G + +LA + + DEI + A AF N
Sbjct: 1 MKIGFIGLGNMGASLAKSVLQTRTS--DEILLANRSQ--AKVDAFIADFGGQASSNEEMF 56
Query: 290 XXXXXXXXXXXXXXXXPALKEIKN-LPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
L + + L ++ L IS+A G+T+ + S +PS+ R+IR+M
Sbjct: 57 AEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKLASLIPSQHRIIRMM 116
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PNTPA + +G +++ AED++L QL G E+ E +DA T L+G GPA+V
Sbjct: 117 PNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGESLIDAATGLAGCGPAFV 176
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEG 823
Y+ IE+LAD GV+ GLPR++AL++AAQT +G+ +V ++ HP +LKD V SP GST G
Sbjct: 177 YLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQHPGVLKDQVCSPGGSTIAG 236
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
LE + FR ++ AV A R + + K
Sbjct: 237 VASLEAHAFRGTVMDAVHQAYKRTQELGK 265
>UniRef50_Q0SF18 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Actinomycetales|Rep: Pyrroline-5-carboxylate reductase -
Rhodococcus sp. (strain RHA1)
Length = 271
Score = 159 bits (385), Expect = 2e-37
Identities = 93/258 (36%), Positives = 135/258 (52%), Gaps = 1/258 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
+I IGGG++ AL +G + AG A D + A HP+ A + T +
Sbjct: 3 RIAVIGGGKIGEALISGLLQAGHAVKDLVVAEQHPARADELAAAYAVRVTTPSDAAEGAD 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
+ +++ L + +L +S+A GI A E+ LP+ V+RVMPN
Sbjct: 63 VIVIAVKPGDVEAALTEVSKVE-LDGEREQLLVSLAAGIPTAFYETRLPAGFPVVRVMPN 121
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TP LV EG + + G E +L + +VG VPE Q+DA+TA+SGSGPAY ++
Sbjct: 122 TPMLVGEGVSVLAPGRHVKKEHLELVRGVLSSVGKVVVVPESQIDAVTAVSGSGPAYFFL 181
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
+ E++ D GV GL R A L QT +GSAAM+ ++G+ L+ VTSP G+TA
Sbjct: 182 VAEAMIDAGVGLGLTRATASELVVQTMVGSAAMLDRSGESATELRAAVTSPGGTTAAAIR 241
Query: 830 HLEKNGFRSAIIGAVSAA 883
LE NG R+A A+ AA
Sbjct: 242 RLEGNGLRTAFFDALEAA 259
>UniRef50_Q27722 Cluster: Pyrroline carboxylate reductase; n=8;
Plasmodium|Rep: Pyrroline carboxylate reductase -
Plasmodium falciparum
Length = 209
Score = 158 bits (384), Expect = 2e-37
Identities = 79/179 (44%), Positives = 106/179 (59%), Gaps = 1/179 (0%)
Frame = +2
Query: 365 PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 544
P +KL IS+ G+ I +E + SE +++ VMPNTP LV EG+ + + D +
Sbjct: 26 PYLSSKLLISICGGLNIGKLEEMVGSENKIVWVMPNTPCLVGEGSFIYCSNKNVNSTDKK 85
Query: 545 LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 724
+ +F + G E+ E MD TA+SG GPAYVY+ IESL D GV+ GL R+L+ L
Sbjct: 86 YVNDIFNSCGIIHEIKEKDMDIATAISGCGPAYVYLFIESLIDAGVKNGLSRELSKNLVL 145
Query: 725 QTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
QT GS MVK D P LKDN+ SP G TA G Y LEKN F+ ++ AV AA ++ K
Sbjct: 146 QTIKGSVEMVKKSDQPVQQLKDNIVSPGGITAVGLYSLEKNSFKYTVMNAVEAACEKSK 204
>UniRef50_P0A9L9 Cluster: Pyrroline-5-carboxylate reductase; n=65;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Shigella flexneri
Length = 269
Score = 156 bits (379), Expect = 1e-36
Identities = 92/267 (34%), Positives = 137/267 (51%), Gaps = 1/267 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KIGFIG G + A+ G I++G P +I D +A Q G A
Sbjct: 4 KIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQ-FGINAAESAQEVAQ 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L EI + + K+ L +S+A G+T+ + L + ++IR MPN
Sbjct: 63 IADIIFAAVKPGIMIKVLSEITSSLN-KDSLVVSIAAGVTLDQLARALGHDRKIIRAMPN 121
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TPALV G + + T ED +F+ G + + E + + +SGS PAYV+M
Sbjct: 122 TPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFM 181
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
IE++AD V G+PR A + AAQ +GSA MV +TG+HP LKD V SP G+T E
Sbjct: 182 FIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVR 241
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKK 910
LE+ GFR+A+I A++ +++ + + K
Sbjct: 242 VLEEKGFRAAVIEAMTKCMEKSEKLSK 268
>UniRef50_A6BFA0 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 173
Score = 156 bits (378), Expect = 1e-36
Identities = 73/171 (42%), Positives = 109/171 (63%), Gaps = 1/171 (0%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
+S+ G+T+ +++ + R++R++PNTPA+V EGA A T ++ + ++
Sbjct: 1 MSIVAGVTVERLQNMIDGTPRILRLLPNTPAMVFEGAFALCSDNDLTEDELEAAKSIYST 60
Query: 569 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 748
+G + +PE+ +DA LSG GPAYV M IE +ADGGV+ GLPR A RLAAQT LG+A
Sbjct: 61 IGVVEMIPEHLLDAACGLSGGGPAYVAMFIEPMADGGVKQGLPRATAYRLAAQTCLGTAK 120
Query: 749 MV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
M+ + G HP LKD VTSP G+T EG LEK G R A+I ++ + ++ +
Sbjct: 121 MILEKGIHPGELKDMVTSPGGTTIEGCEALEKAGMRGAVIECINVSTEKSR 171
>UniRef50_A0LDU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Magnetococcus sp. MC-1|Rep: Pyrroline-5-carboxylate
reductase - Magnetococcus sp. (strain MC-1)
Length = 270
Score = 156 bits (378), Expect = 1e-36
Identities = 81/178 (45%), Positives = 114/178 (64%), Gaps = 2/178 (1%)
Frame = +2
Query: 371 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 550
A + +S+A G+ + T+ + LP+ +IR MPNTPALV +G AE
Sbjct: 89 APTAVVLSIAAGVDLTTMAAALPAGQPIIRAMPNTPALVGQGMTVLCPNGHVDAEQLAQA 148
Query: 551 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 727
+L ++VG V E MD +TALSGSGPAY++++ E+L+DGGV CGLPR LA +LA Q
Sbjct: 149 QRLLESVGQVAVVKQESLMDGVTALSGSGPAYLFLIAEALSDGGVACGLPRALADQLAVQ 208
Query: 728 TTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
T LGSA +++ +G+HP +LK+ VTSP G+T G LE+ G R A++ AV AA +R K
Sbjct: 209 TLLGSATLLRESGEHPGVLKNRVTSPGGTTIAGLGVLERQGVRGALMAAVEAAWNRSK 266
>UniRef50_Q1F0K7 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Clostridium oremlandii OhILAs|Rep: Delta
1-pyrroline-5-carboxylate reductase - Clostridium
oremlandii OhILAs
Length = 273
Score = 155 bits (377), Expect = 2e-36
Identities = 91/268 (33%), Positives = 132/268 (49%), Gaps = 1/268 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
+IGFIG G ++ + G + + I S A K + N
Sbjct: 4 RIGFIGAGNMSSTIIRGLVKSFEGMNQSIYISNRTIKKAE-KLCNQVHINLCRTNVELAE 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L+EI + + K+++ +S+A GIT + ++IR+MPN
Sbjct: 63 NSDIIFLGVKPHMYDGVLREISSYVT-KDQIIVSLAAGITTEDMGEYFKEPMKIIRIMPN 121
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
P V EG A S T E+ QL +VG D++ E +DA+T +SG PA++ M
Sbjct: 122 VPVSVGEGMIALSSNGNVTGEEVDFVVQLLSSVGKVDQIDESLIDAVTTISGCSPAFIAM 181
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
+E+LADG VR G+PRD A AAQT +G+ M+ + G HP LKD V+SP G T EG Y
Sbjct: 182 FVEALADGSVRKGMPRDKAYLYAAQTLIGTGKMILEKGLHPGELKDMVSSPGGVTIEGVY 241
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
LEK GFR+ +I V A + K +K +
Sbjct: 242 ELEKRGFRNMLIEVVEACERKTKSMKSK 269
>UniRef50_Q4QFY6 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Trypanosomatidae|Rep: Pyrroline-5-carboxylate reductase
- Leishmania major
Length = 272
Score = 155 bits (375), Expect = 3e-36
Identities = 90/272 (33%), Positives = 144/272 (52%), Gaps = 1/272 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
+KIGF+G G + + G + A P+ T C+ S ++ + L
Sbjct: 4 LKIGFLGCGSMGECIMAGLLKAKALGPEN-TFICNRS-ASTNERLVSLYQVKSVSAVELA 61
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
P L+ IK +KL +S+A G+ IAT+E++ P + +V+RVMP
Sbjct: 62 EKSDIIMLGVKPYGIVPVLETIKE-KITPSKLVVSMAAGVPIATIENHCPPKTKVVRVMP 120
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N P+ V EG + S + T +D + +LF A+G V E + + ++GS PAYV+
Sbjct: 121 NIPSYVGEGVTSISGNSAVTPDDEAVVMKLFSAIGKSYLVAESAIHGVVGVAGSSPAYVF 180
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGT 826
M +E+L+DG VR G+PR + +AAQ LG+A M++ +G P+ LKD V SP G+T E
Sbjct: 181 MFMEALSDGAVRGGIPRAQSYEMAAQAVLGAAKMLQDSGKTPSALKDMVCSPGGTTIEAV 240
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 922
LEK G RS+II A+ +++ K ++ ++
Sbjct: 241 RFLEKGGMRSSIIEAMIQCMEKSKEFERMYSE 272
>UniRef50_Q0AYD4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Pyrroline-5-carboxylate reductase - Syntrophomonas
wolfei subsp. wolfei (strain Goettingen)
Length = 268
Score = 153 bits (372), Expect = 7e-36
Identities = 78/171 (45%), Positives = 111/171 (64%), Gaps = 1/171 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L IS+A GI + E+ + V+RVMPNTP LV +G +A S G AT ++ QL +++F
Sbjct: 91 LLISLAAGIKTGSYENEIGLHLPVVRVMPNTPCLVGQGVSAISPGRYATDKNLQLVAKMF 150
Query: 563 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
+ +GTC V E MDAITA+SGSGPAYV++++ESL + ++ GL LA +L T GS
Sbjct: 151 EQLGTCVMVEEKHMDAITAISGSGPAYVFLVVESLMNAALQVGLDLKLARQLVVNTVKGS 210
Query: 743 AAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
M+ ++G+HPA+L++ V SP G+T G LE+NG R A AV A +R
Sbjct: 211 MEMMEQSGEHPAILREQVCSPGGTTIAGIRQLEENGLRRAFFQAVEKAYER 261
>UniRef50_Q8S488 Cluster: Delta-1-pyrroline-5-carboxylate reductase;
n=1; Phytophthora nicotianae|Rep:
Delta-1-pyrroline-5-carboxylate reductase - Phytophthora
nicotianae (Buckeye rot agent)
Length = 314
Score = 153 bits (372), Expect = 7e-36
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 2/267 (0%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENX 280
++ ++ IGGG +A A+ G ++ GL ++ S P+ K + L N
Sbjct: 35 LDLNRLAVIGGGNMAEAIITGVLTEGLIPSSKVVVS-DPNPSMRGK-YAKLNVETHTRNS 92
Query: 281 XXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIR 460
L+ +K + L ISV G +I ++ +L ++ +IR
Sbjct: 93 SAVKDADVILVAVKPQVVDDVLRAVK-ASMDPDALVISVVAGQSIKQLQQHLGQDSHIIR 151
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGP 637
MPNTPA++ EG +++ + T+ +LT Q+ + G V E +D TALSGSGP
Sbjct: 152 TMPNTPAMIGEGTTVWAQSAEVTSVQHELTKQILGSFGVEVFVDDENALDMATALSGSGP 211
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGST 814
AY +++ E++ D GV G R +A +L QT LGSA +++ D HP L++N+TSP G+T
Sbjct: 212 AYFFLVAEAMIDTGVHMGFSRPVATKLVQQTMLGSALYMQSEDVHPVELRNNITSPGGTT 271
Query: 815 AEGTYHLEKNGFRSAIIGAVSAAVDRC 895
A G Y EKNGFR+ I ++ AA +RC
Sbjct: 272 AAGLYRAEKNGFRAVIADSIWAAYERC 298
>UniRef50_Q3AAH4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep:
Pyrroline-5-carboxylate reductase - Carboxydothermus
hydrogenoformans (strain Z-2901 / DSM 6008)
Length = 259
Score = 152 bits (369), Expect = 2e-35
Identities = 81/187 (43%), Positives = 117/187 (62%), Gaps = 2/187 (1%)
Frame = +2
Query: 344 LKEIKNLPSAKNKLFISVAMGITIATV-ESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 520
+KEI P K+ +SVA G+++ + E +P E V+RVMPNTPAL+ +G A + +
Sbjct: 77 IKEIS--PGLSGKILVSVAAGVSLKKIAEWGVPGECEVVRVMPNTPALIGQGFIAITP-S 133
Query: 521 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 700
KA A L +++F ++G + E D ITAL+GSGPAY+Y++ E+L DG VR GLPR
Sbjct: 134 KANA----LLAEIFDSLGEVVFLEEKYFDQITALAGSGPAYIYLVAEALIDGAVRLGLPR 189
Query: 701 DLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 877
D+A QT +G+ AM+K T +HP +L+D V +P G+TA G Y LEK G R +
Sbjct: 190 DVARSAVVQTLIGAGAMLKETQEHPGILRDAVVTPGGTTAAGLYQLEKQGIRGMFADCLE 249
Query: 878 AAVDRCK 898
+A +R K
Sbjct: 250 SAYERAK 256
>UniRef50_A3DD78 Cluster: Pyrroline-5-carboxylate reductase
precursor; n=2; Clostridium|Rep: Pyrroline-5-carboxylate
reductase precursor - Clostridium thermocellum (strain
ATCC 27405 / DSM 1237)
Length = 271
Score = 152 bits (368), Expect = 2e-35
Identities = 94/267 (35%), Positives = 131/267 (49%), Gaps = 1/267 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
+IGFIG G + A+ +G+ + I D S + G T
Sbjct: 4 RIGFIGAGNMGGAMITSIAQSGIIPAENILVFDVDRDKLSVLR-EKTGITITDSALETVR 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L +IK NK+ +SVA+GI I + L + IR MPN
Sbjct: 63 KSDIIILAVKPNMVKAVLNDIKPAVD-NNKILVSVAVGIPIKFYKEMLGENIKFIRTMPN 121
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TPALV EG ++A+ ++F+ G + + E M +TA++ S PAYV+M
Sbjct: 122 TPALVGEGMTLMCCDKNVDEKEAEQVKKIFECFGKVEFLEEKLMSEVTAVTSSSPAYVFM 181
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
IE++AD V G+PR+LA +L+AQ LG+A MV +TG HP LKD V SPAG+T E
Sbjct: 182 FIEAMADAAVLSGIPRNLAYKLSAQAVLGAAKMVLETGKHPGELKDQVCSPAGTTIEAVR 241
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKK 910
LEKN FR AII A+S + + K
Sbjct: 242 SLEKNRFRYAIIEAMSECTKKALEIGK 268
>UniRef50_A5Z6I9 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 273
Score = 151 bits (365), Expect = 5e-35
Identities = 79/179 (44%), Positives = 108/179 (60%), Gaps = 2/179 (1%)
Frame = +2
Query: 377 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAE-DAQLTS 553
+K+ IS+A G TI ++ L + R++R MPNTPA++ EG E + + +
Sbjct: 96 DKVIISLAPGFTITQLKEKLKA-GRIVRSMPNTPAMIGEGMTGVCFDENEFDENEIDVIN 154
Query: 554 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 733
++F+A G +V E M+++ SGS PAYV+M IE+LAD V+CGLPR A AQT
Sbjct: 155 KIFEATGKAKKVDEKLMNSVVCASGSSPAYVFMFIEALADSAVKCGLPRKDAYEFVAQTV 214
Query: 734 LGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 907
LGSA M++TG HP LKD V SP G+T G LEKNGFR AI A A ++C +K
Sbjct: 215 LGSAKLMLETGKHPGELKDMVCSPGGTTIAGVAELEKNGFRKAIFEATDACFNKCNNIK 273
>UniRef50_Q67QH2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Symbiobacterium thermophilum|Rep:
Pyrroline-5-carboxylate reductase - Symbiobacterium
thermophilum
Length = 284
Score = 150 bits (364), Expect = 6e-35
Identities = 87/262 (33%), Positives = 131/262 (50%), Gaps = 1/262 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
+GF+G G +A AL G ++AG+ +P+++ S A + G
Sbjct: 9 VGFLGAGAIAEALIRGMLNAGVVQPEQVLVSNRSDRERLADLNRRYGVRTAGSKGYVVDV 68
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
L E+ ++ +S+A GI + +E + V+R MPNT
Sbjct: 69 CQVVVLACKPKDVAGLLAEVGGR-FRPGQIVLSLAAGIATSFIEERVADGVMVVRAMPNT 127
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYML 655
V E A A G AT E +L +++ +VG VPE QMDA+T LSGSGPAYVY +
Sbjct: 128 SCQVGESATAVCLGRAATPEAMRLVTEMLASVGQVYTVPEEQMDAVTGLSGSGPAYVYYI 187
Query: 656 IESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYH 832
+E++ + G GL ++A L QT G+A + TG PA+L++ VTSP G+TA G
Sbjct: 188 VEAMIEAGEAVGLAPEVARALTLQTLKGAALTLATTGADPAVLREQVTSPGGTTAAGLQV 247
Query: 833 LEKNGFRSAIIGAVSAAVDRCK 898
L + GF A+I A+ A +R +
Sbjct: 248 LREAGFAQALISAIVRATERSR 269
>UniRef50_Q233Y5 Cluster: Pyrroline-5-carboxylate reductase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyrroline-5-carboxylate reductase family protein -
Tetrahymena thermophila SB210
Length = 336
Score = 150 bits (364), Expect = 6e-35
Identities = 96/263 (36%), Positives = 136/263 (51%), Gaps = 2/263 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFE-NXXX 286
+KI FIG G++A A+A G + +G P + TA+ S+ + + T + + N
Sbjct: 66 LKITFIGAGKMATAIAGGLVKSGKYTPSQFTAT-DKSEASREHFIEKSQVTNIIQDNILA 124
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
KEI + ++KL IS+A G + T L R+IRVM
Sbjct: 125 SKFSDVIILAVKPQQIEEVCKEIAEV--CQDKLIISIAAGTKLETFYK-LFGHKRIIRVM 181
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PNTP +V GA+AFS G + D + +F VG +V E MDA+TA+SGSGPAYV
Sbjct: 182 PNTPMMVGIGASAFSMGDQCKETDRDICLSIFSPVGKIHQVEECHMDAVTAVSGSGPAYV 241
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEG 823
+ I++LAD GV+ GL +++L LA QT LG+A MV P L VTSP G+T
Sbjct: 242 FQFIKALADAGVQQGLQPEVSLDLATQTVLGAAMMVSLNQGTPEELTKAVTSPNGTTYAA 301
Query: 824 TYHLEKNGFRSAIIGAVSAAVDR 892
+EK F+ + V AA +R
Sbjct: 302 LCCMEKLQFKETVYKFVEAATNR 324
>UniRef50_Q86ER8 Cluster: Clone ZZD150 mRNA sequence; n=3;
Schistosoma japonicum|Rep: Clone ZZD150 mRNA sequence -
Schistosoma japonicum (Blood fluke)
Length = 313
Score = 150 bits (363), Expect = 8e-35
Identities = 97/306 (31%), Positives = 147/306 (48%), Gaps = 10/306 (3%)
Frame = +2
Query: 23 ILXISSQWSNAVEFARDVLYVRKLPLIEAMKIGFIGGGRLAFALANGFISAGLAKPDEIT 202
I+ SS + N + R + ++ + GF+G G ++ AL GF+S+ ++T
Sbjct: 8 IVRKSSLFENILYTKRYGMSTDVKTILASKHYGFLGSGNMSQALVKGFLSSNTINSSQVT 67
Query: 203 AS-----CHPS---DVASAKAFQGLGATALFENXXXXXXXXXXXXXXXXXXXXPALKEIK 358
+ P ++ G L N P LK +
Sbjct: 68 MTDRFGLSFPDAELQISLKSLCSKYGVEYLQANEPMVEKSDIIFACVKPHILLPVLKGLW 127
Query: 359 NLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED 538
N NKL IS+A GIT+ ++ +P+ R+IR+MPNTP V G A ++ + T D
Sbjct: 128 N--RLDNKLLISIAAGITLDQIQKAVPTSTRIIRIMPNTPCQVGVGTAVYAHTSTVTEHD 185
Query: 539 AQLTSQLFKAVGTCDE-VPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 715
QL S L ++ E +PE +A A+SGS PA++YM+ E++ D GV GLPR A +
Sbjct: 186 IQLISALCSSIFPVFEAIPESLFNAAVAMSGSSPAFIYMVAEAITDAGVLLGLPRATAQK 245
Query: 716 LAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
L T LGSA M++ D + LK+NV SP G+T G Y LEK R+ ++ AV R
Sbjct: 246 LIVNTILGSAVMMQKSDKNTTELKNNVCSPGGTTIHGVYALEKGNLRATLMDAVQKVCAR 305
Query: 893 CKIVKK 910
+ + K
Sbjct: 306 GEELSK 311
>UniRef50_Q2ZZM3 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=4; Lactobacillales|Rep: Delta
1-pyrroline-5-carboxylate reductase - Streptococcus suis
89/1591
Length = 261
Score = 148 bits (359), Expect = 3e-34
Identities = 101/271 (37%), Positives = 147/271 (54%), Gaps = 3/271 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPD-EITASCHPSDVASAKAFQGLGATALFENXXX 286
MKIGFIG G + ALA+ A +PD ++ S H + A A+ Q LF N
Sbjct: 1 MKIGFIGLGNMGAALAH----AVSQQPDTQLLLSNH--NPAKAQVLQEKVGGQLFSNGEI 54
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAK-NKLFISVAMGITIATVESNLPSEARVIRV 463
L +++ S + ++IS+A G+ + ++ + + ++ ++IR+
Sbjct: 55 AEQAKVIFLGVKPHLIQTVLSGLQDQISQNPSAIWISMAAGVPLDSLAAFVSAD-KLIRI 113
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
MPNTP + +G +S E A L Q+ + G +VPE +DA TA++G GPA+
Sbjct: 114 MPNTPVAIGQGMTTYSL---VNQELAPLLEQILEKSGKVQQVPESLIDAATAIAGCGPAF 170
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAE 820
VY +IE+L D GV+ GL A LAAQT G+A MV T D HPA L+ VTSP GST
Sbjct: 171 VYQMIEALTDAGVQNGLTAQDAKVLAAQTLAGTAQMVLTSDKHPAQLRQEVTSPGGSTIA 230
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
G LEK GFR AII AV+AA+ + + + K+
Sbjct: 231 GVVALEKEGFRYAIIRAVAAALKKTRKLGKK 261
>UniRef50_P14383 Cluster: Pyrroline-5-carboxylate reductase 1; n=5;
Bacillus|Rep: Pyrroline-5-carboxylate reductase 1 -
Bacillus subtilis
Length = 297
Score = 148 bits (358), Expect = 3e-34
Identities = 89/284 (31%), Positives = 139/284 (48%), Gaps = 1/284 (0%)
Frame = +2
Query: 92 LPLIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALF 271
LP+ + K+ FIG G +A + +G + A I + + + G
Sbjct: 11 LPIFDQKKVAFIGAGSMAEGMISGIVRANKIPKQNICVTNRSNTERLTELELQYGIKGAL 70
Query: 272 ENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEAR 451
N AL +K+ ++L +SV GIT + +E +L +E
Sbjct: 71 PNQLCIEDMDVLILAMKPKDAENALSSLKSRIQP-HQLILSVLAGITTSFIEQSLLNEQP 129
Query: 452 VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGS 631
V+RVMPNT +++ A A + G + + +L L +G + E QMD T ++GS
Sbjct: 130 VVRVMPNTSSMIGASATAIALGKYVSEDLKKLAEALLGCMGEVYTIQENQMDIFTGIAGS 189
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAG 808
GPAY Y L+E + G GL + L+ + AQT LG+A M ++TG+HP +L+DN+TSP G
Sbjct: 190 GPAYFYYLMEFIEKTGEEAGLDKQLSRSIGAQTLLGAAKMLMETGEHPEILRDNITSPNG 249
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLNDXTA*LS 940
+TA G L+K+G AI A+ A R K + + + A LS
Sbjct: 250 TTAAGLQALKKSGGGEAISQAIKHAAKRSKEISEDIEKTAAPLS 293
>UniRef50_A0K0A3 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Arthrobacter|Rep: Pyrroline-5-carboxylate reductase -
Arthrobacter sp. (strain FB24)
Length = 277
Score = 147 bits (356), Expect = 6e-34
Identities = 94/275 (34%), Positives = 139/275 (50%), Gaps = 7/275 (2%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALF------E 274
+I F+G G + A+ +G + AG P ++ A+ ++ A+ A + G TA+
Sbjct: 4 RIAFLGCGSMNEAVMSGMLEAG-TDPADVVATVRRAERAAELAQRHAGITAIAGEEEPEN 62
Query: 275 NXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARV 454
N +EI S + + +SVA ++IA +E+ LP+ V
Sbjct: 63 NKQAATGADVVILGVKPVGITDLAREISGSLSPE-AIVVSVAAAVSIAQLEAALPAGQPV 121
Query: 455 IRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSG 634
IR MPNTPA + G + S GT +AE QL + K GT EVPE Q+DA++A+SGSG
Sbjct: 122 IRTMPNTPAKLGRGVVSVSPGTNCSAEQLQLAKNILKGAGTVVEVPEEQVDALSAISGSG 181
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGS 811
PAYV+ L E++A GV GL +L+L LA +T G M+ + G P L+ VTSP G+
Sbjct: 182 PAYVFYLAEAMAAAGVELGLDPELSLLLARETVAGGGLMLAEPGADPTALRKAVTSPNGT 241
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
T ++ G + I AA R + KQL
Sbjct: 242 TERAIATFDERGLPAIIADGARAAAARAAEITKQL 276
>UniRef50_P54552 Cluster: Pyrroline-5-carboxylate reductase 2; n=4;
Bacillus|Rep: Pyrroline-5-carboxylate reductase 2 -
Bacillus subtilis
Length = 278
Score = 147 bits (356), Expect = 6e-34
Identities = 84/268 (31%), Positives = 133/268 (49%), Gaps = 1/268 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KIGF+G G +A A+ NG + +G+ KP+ I + +D + + +
Sbjct: 3 KIGFVGAGSMAEAMINGILQSGITKPEHIYITNRSNDERLIELKETYSVRPCRDKNEFFT 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
++ I+ P K++L ISV G+TI T++ + VIRVMPN
Sbjct: 63 HTDIIILAFKPKDAAESIDSIR--PYIKDQLVISVLAGLTIETIQHYFGRKLAVIRVMPN 120
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
T A +++ A FS T+A+ D L + +G V E +DA+TA++GSGPAYVY
Sbjct: 121 TSAAIRKSATGFSVSTEASKNDIIAAKALLETIGDATLVEERHLDAVTAIAGSGPAYVYR 180
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTY 829
IE++ + GL ++ A L QT G+ M +++G P L+ +TSP G+T G
Sbjct: 181 YIEAMEKAAQKVGLDKETAKALILQTMAGATDMLLQSGKQPEKLRKEITSPGGTTEAGLR 240
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
L+ + F AII + R +K+Q
Sbjct: 241 ALQDSRFEEAIIHCIEETAKRSAEIKEQ 268
>UniRef50_A4J3P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Desulfotomaculum reducens MI-1|Rep:
Pyrroline-5-carboxylate reductase - Desulfotomaculum
reducens MI-1
Length = 281
Score = 146 bits (353), Expect = 1e-33
Identities = 82/266 (30%), Positives = 134/266 (50%), Gaps = 1/266 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
++E F+G G + ++ G +SAG+ +P EI + + G + +
Sbjct: 1 MLEGKTFFFVGAGNICESMIKGILSAGIVRPGEIRVANRSNTERLNYLRNYYGIVPVTDK 60
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
AL E+++ + +N++ ISV G+ + +E +L ++ VI
Sbjct: 61 QTAAAKADIIVLAMKPQDVFAALDELRD-STQENQIIISVLAGVPTSLIEDSLNTQIAVI 119
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGP 637
R MPNT + E A S G T +L ++F +G V E+ +DA+T LSGSGP
Sbjct: 120 RAMPNTSCAILESATGLSAGRFTTPNQLKLAEEIFCMMGEVVVVEEHLLDAVTGLSGSGP 179
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGST 814
AY+Y L+E++ G G+PR+LA L +T LG+A M ++TG++P L+ VTSP G+T
Sbjct: 180 AYIYYLVEAMEKAGETAGIPRELARPLVLKTLLGAAKMLMETGENPEELRRQVTSPNGTT 239
Query: 815 AEGTYHLEKNGFRSAIIGAVSAAVDR 892
G L K F++ + A+ A R
Sbjct: 240 MAGINELNKGDFQNTLRKAILKATRR 265
>UniRef50_P0C1E4 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Corynebacterium|Rep: Pyrroline-5-carboxylate reductase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 270
Score = 146 bits (353), Expect = 1e-33
Identities = 90/269 (33%), Positives = 138/269 (51%), Gaps = 3/269 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I IGGG++ AL +G I+A + P I + + S+ + G + +N
Sbjct: 4 IAVIGGGQIGEALVSGLIAANM-NPQNIRVT-NRSEERGQELRDRYGILNMTDNSQAADE 61
Query: 296 XXXXXXXXXXXXXXPALKEIKNL--PSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L EI ++ + +S+A GI+IA +E + + V+RVMP
Sbjct: 62 ADVVFLCVKPKFIVEVLSEITGTLDNNSAQSVVVSMAAGISIAAMEESASAGLPVVRVMP 121
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
NTP LV +G + ++G AE + L VG EV E +DA+TA+SGS PAY++
Sbjct: 122 NTPMLVGKGMSTVTKGRYVDAEQLEQVKDLLSTVGDVLEVAESDIDAVTAMSGSSPAYLF 181
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGT 826
++ E+L + GV GLPR A +LA + G+A M+K TG P+ L+ V+SPAG+T
Sbjct: 182 LVTEALIEAGVNLGLPRATAKKLAVASFEGAATMMKETGKEPSELRAGVSSPAGTTVAAI 241
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
LE++G R A A A DR + + K+
Sbjct: 242 RELEESGIRGAFYRAAQACADRSEELGKR 270
>UniRef50_Q11141 Cluster: Pyrroline-5-carboxylate reductase; n=18;
Corynebacterineae|Rep: Pyrroline-5-carboxylate reductase
- Mycobacterium tuberculosis
Length = 295
Score = 145 bits (352), Expect = 2e-33
Identities = 105/285 (36%), Positives = 143/285 (50%), Gaps = 25/285 (8%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVAS--AKAFQGLGATALFENXXX 286
+I IGGG + AL +G + AG D + A P D A+ A+ + L +A
Sbjct: 7 RIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMP-DRANYLAQTYSVLVTSAA----DA 61
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKN-----KLFISVAMGITIATVESNLPSEAR 451
P + ++ N +A ++F++V GITIA ES LP+
Sbjct: 62 VENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTP 121
Query: 452 VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGS 631
V+R MPN ALV G A ++G T + + S LF AVG VPE Q+DA+TA+SGS
Sbjct: 122 VVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGS 181
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV----------KTGD----- 766
GPAY ++L+E+L D GV GL R +A LAAQT GSAAM+ G+
Sbjct: 182 GPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLR 241
Query: 767 ---HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
+ L+ VTSP G+TA LE+ GFR A+ AV AA R
Sbjct: 242 VDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSR 286
>UniRef50_Q6AAZ1 Cluster: Putative delta-1-pyrroline-5-carboxylate
reductase; n=1; Propionibacterium acnes|Rep: Putative
delta-1-pyrroline-5-carboxylate reductase -
Propionibacterium acnes
Length = 263
Score = 145 bits (351), Expect = 2e-33
Identities = 89/260 (34%), Positives = 133/260 (51%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KI +G G +A AL G I AG K +++ A+ + A LG T +N
Sbjct: 4 KIAVLGCGTMAGALVGGLIDAGQMKAEDVVATARSASHRDEIA-NTLGVTTSGDNTTAVR 62
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L+E+ A + + +S+A G+T T + + + +++RVMPN
Sbjct: 63 DADLVILGVKPYAAVDVLEEVSGALKA-DAVVVSIAAGVT--TEKLLMAWQGKIVRVMPN 119
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TP V +GA S + + A+ L ++VG VPE +A TA+SGSGPAYV++
Sbjct: 120 TPVRVGKGAFIVS-SAPGSEDAAKKVGDLLESVGVVVTVPEELHNAATAVSGSGPAYVFL 178
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYH 832
+ E++ D V G+PRD A +L T GSA ++ G+HPA+L+ VTSP G+TA
Sbjct: 179 VAEAMIDAAVALGVPRDQASQLTVATLAGSAELLAGGEHPAVLRSKVTSPGGTTAAAVAA 238
Query: 833 LEKNGFRSAIIGAVSAAVDR 892
LE G RS A++A DR
Sbjct: 239 LEAGGVRSVFADAMTACRDR 258
>UniRef50_Q9P7Y7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Schizosaccharomyces pombe|Rep: Pyrroline-5-carboxylate
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 282
Score = 145 bits (351), Expect = 2e-33
Identities = 73/180 (40%), Positives = 106/180 (58%)
Frame = +2
Query: 344 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 523
L K + K KL +S+ G TI++++S L RVIR+MPNT + ++E + G
Sbjct: 94 LNSPKMKEALKGKLILSILAGKTISSLQSMLDESTRVIRIMPNTASRIRESMSVICPGPN 153
Query: 524 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 703
AT ED + +F +G ++PE +DA TA+ GSGPA+V +IE++ DGGV G+P
Sbjct: 154 ATEEDIKFAEWVFNGIGRSMKLPEKLIDAATAVCGSGPAFVATMIEAMTDGGVMMGIPFP 213
Query: 704 LALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
A LAAQT +G+ MV G HPAM++++V++PAG T G LE RS I + A
Sbjct: 214 QAQELAAQTMVGTGRMVLQGQHPAMIRNDVSTPAGCTISGLLALEDGKIRSTIARGIEQA 273
>UniRef50_Q6AL13 Cluster: Related to pyrroline-5-carboxylate
reductase; n=1; Desulfotalea psychrophila|Rep: Related
to pyrroline-5-carboxylate reductase - Desulfotalea
psychrophila
Length = 272
Score = 142 bits (345), Expect = 1e-32
Identities = 88/267 (32%), Positives = 139/267 (52%), Gaps = 2/267 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
IGFIGGG++A AL G +G + P E PS + +
Sbjct: 6 IGFIGGGQMAEALIKGLTQSG-SYPAENIYVLDPSPERKDFLTATYNINTIEDCGAAFAT 64
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLP-SEARVIRVMPN 472
L+ + + + ++ L I++A G+ I++ L ++IRVMPN
Sbjct: 65 CQKIFLAVKPQVMSLVLQNCQGIIN-EDHLLITIAAGLPISSYVKTLALPRLKIIRVMPN 123
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TPALV + A+A + + E+ +F +GT + E +DA+T LSGSGPAYV+
Sbjct: 124 TPALVGQSASALTASPYVSQEELDKVQNIFNQIGTTTVLEECHLDAVTGLSGSGPAYVFS 183
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTY 829
IE+L D GV GL R ++ LA QT GS +++ G+HPA+ + V+SP G+T +
Sbjct: 184 FIEALIDAGVAEGLNRQVSTNLALQTVAGSVELLRQNGEHPAVERARVSSPGGTTIAASK 243
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKK 910
LE++GF++ I+ AV+AA ++ K + K
Sbjct: 244 ILERSGFQAIIMDAVAAATEKSKELGK 270
>UniRef50_Q836Y3 Cluster: Pyrroline-5-carboxylate reductase,
putative; n=1; Enterococcus faecalis|Rep:
Pyrroline-5-carboxylate reductase, putative -
Enterococcus faecalis (Streptococcus faecalis)
Length = 271
Score = 141 bits (341), Expect = 4e-32
Identities = 93/272 (34%), Positives = 132/272 (48%), Gaps = 4/272 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAF-QGLGATALFENXXX 286
MKI FIG G +A A+A G + + + + V AF Q +GA A+
Sbjct: 1 MKISFIGAGNMASAIAKGALKKQFIAAENLYF--YDIQVEKTAAFAQEIGAHAVASPQEA 58
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVES--NLPSEARVIR 460
AL E K K L +S+A G TIA + R++R
Sbjct: 59 ITVADLVILAVKPQFVQAALLEAKEAILDKQPLIVSIAAGTTIAELYQLFETTQPLRLVR 118
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPA 640
VMPN AL+ GAAA A+ ED Q LF+AVG E+ E TA++GS PA
Sbjct: 119 VMPNMNALIGAGAAAVCGNAFASPEDIQTVLSLFRAVGQAWELEEQYFSIFTAIAGSTPA 178
Query: 641 YVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTA 817
Y ++ I+S+A V+ G+ ++LAL +A Q LGSA + + ++P L D V+SP G+T
Sbjct: 179 YAFLFIDSIARAAVKNGMNKELALEIATQAVLGSAQTLANSTENPWTLIDQVSSPGGTTV 238
Query: 818 EGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
G LE N F S +I + A + R + + KQ
Sbjct: 239 AGIVELENNAFISTVIKGIEATILRDQELAKQ 270
>UniRef50_Q5KFS4 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Basidiomycota|Rep: Pyrroline-5-carboxylate reductase -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 313
Score = 140 bits (340), Expect = 5e-32
Identities = 75/173 (43%), Positives = 105/173 (60%), Gaps = 1/173 (0%)
Frame = +2
Query: 374 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 553
+ KL IS+ G+TI+ ++S +P RV+R MPNTP + EG + + A + L
Sbjct: 133 EGKLLISICAGVTISQLKSWVPESTRVVRAMPNTPCKIGEGMTIVTPLSDALSRT--LIL 190
Query: 554 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 733
+F + G C + E DA TAL+GSGPA+V +++E++ADGGV GLPR AL LAAQT
Sbjct: 191 NIFTSCGRCRFLDEKHFDACTALAGSGPAFVALVLEAMADGGVMMGLPRSEALELAAQTM 250
Query: 734 LGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVD 889
G+ M ++TG HPA LKD+VT+P G T G LE RS + A+ A +
Sbjct: 251 QGTGRMALQTGLHPAQLKDSVTTPGGCTIAGLLTLEDGRVRSTMARAIQVATN 303
>UniRef50_Q8F631 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Leptospira|Rep: Pyrroline-5-carboxylate reductase -
Leptospira interrogans
Length = 273
Score = 140 bits (339), Expect = 7e-32
Identities = 82/180 (45%), Positives = 110/180 (61%), Gaps = 7/180 (3%)
Frame = +2
Query: 380 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 559
K ISVA GI I T+ NLP+ + V+RVMPN P LV EGA F E + S++
Sbjct: 94 KKIISVAAGIHIDTILKNLPTGSNVVRVMPNLPLLVSEGAIGFF----GDEELYETVSEI 149
Query: 560 FKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 736
F+ +G ++ E MDA+T LSGSGPAYV+ I++LA+GGV GL AL L+ QT +
Sbjct: 150 FQPLGHSVKLGSETLMDAVTGLSGSGPAYVFKFIQALAEGGVLSGLGYQEALDLSIQTVI 209
Query: 737 GSAAMVK------TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
GSA +++ HP + K+ VTSP G+T G LEKNGF +A++ AV AA +R K
Sbjct: 210 GSAQLLRKEREKDPTTHPEVWKNKVTSPGGTTIAGLVELEKNGFSNAVLEAVKAAANRSK 269
>UniRef50_A5WCA1 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Moraxellaceae|Rep: Pyrroline-5-carboxylate reductase -
Psychrobacter sp. PRwf-1
Length = 282
Score = 138 bits (334), Expect = 3e-31
Identities = 91/281 (32%), Positives = 142/281 (50%), Gaps = 7/281 (2%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPS----DVASAKAFQGLGATAL 268
++ KI FIGGG +A AL +G ++ G+ KP++IT + PS DV ++ + T
Sbjct: 4 LKGKKISFIGGGNMAQALISGLLARGI-KPNDITVA-DPSQDIRDVLKSQKINTVDPTGT 61
Query: 269 FENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNK-LFISVAMGITIATVESNLPSE 445
+ K + + ++ L ISVA G++ ++ L
Sbjct: 62 TDTNNPQIAAKTADVIVLAVKPQVMDKVVADFADVLDRQLVISVAAGLSTDSLSKMLSGY 121
Query: 446 ARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITAL 622
++R MPNTPA++++GA + D QL + L A G V E Q+ A+TA+
Sbjct: 122 QNIVRAMPNTPAMIQKGATGLYANDSISETDKQLAATLMAASGLVSWVEQEEQLHAVTAV 181
Query: 623 SGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTS 799
SGS PAY + +IES+ + GV GL R A LA QT LG+A M + +G+ PA L+ VTS
Sbjct: 182 SGSAPAYFFYMIESMIEAGVEQGLDRKQAAALAMQTALGAAQMAITSGEAPAELRRKVTS 241
Query: 800 PAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 922
P G+T L+++ F I A+ A R + + ++L D
Sbjct: 242 PNGTTQAAIESLQQDDFAGIIKKAMQACYTRSEQISQELAD 282
>UniRef50_Q831S6 Cluster: Pyrroline-5-carboxylate reductase,
putative; n=1; Enterococcus faecalis|Rep:
Pyrroline-5-carboxylate reductase, putative -
Enterococcus faecalis (Streptococcus faecalis)
Length = 260
Score = 138 bits (333), Expect = 4e-31
Identities = 89/261 (34%), Positives = 126/261 (48%), Gaps = 3/261 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKIGFIG G + A+ G + A K + + S +A+A Q L +
Sbjct: 1 MKIGFIGAGSMGGAMIKGLLKAEAVKKEHLYVKGGSS--GTAEALQKEWGFQLVTDYALF 58
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNK-LFISVAMGITIATVESNLPS-EARVIRV 463
P L+E+ P N+ L ISVA G TI + L + EA+V+
Sbjct: 59 QECKVIFIATGAKVVLPVLQELA--PHFSNESLLISVATGHTIQEAQMALGNKEAKVVHA 116
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
+PNTP V +G + + L +L +G E+ E Q++ ++G PA+
Sbjct: 117 IPNTPVSVNQGVIGVALAPTIEGQTKDLAMELLATLGLVKEIREAQLETFGTVAGCSPAF 176
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAE 820
V + +E+L D V GLPRDL+ + AQ G+A + + T HP LKD VTSP GST
Sbjct: 177 VDIFMEALGDAAVLEGLPRDLSYEIVAQMIKGTATLALDTKKHPGALKDEVTSPGGSTIR 236
Query: 821 GTYHLEKNGFRSAIIGAVSAA 883
G LEKNGFR A++ AV A
Sbjct: 237 GVVALEKNGFRYAVMDAVQQA 257
>UniRef50_Q64E79 Cluster: Pyrroline-5-carboxylate reductase; n=1;
uncultured archaeon GZfos13E1|Rep:
Pyrroline-5-carboxylate reductase - uncultured archaeon
GZfos13E1
Length = 295
Score = 138 bits (333), Expect = 4e-31
Identities = 91/272 (33%), Positives = 133/272 (48%), Gaps = 5/272 (1%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEIT-ASCHPSDVASAKAFQGLGATALFENXXXX 289
KIG IG G + ++ G ++A IT A A G N
Sbjct: 20 KIGIIGVGNIGASILRGLLTAEPTSKIFITDAENEKRRFFEADLGTDSGVVVCKTNEEVA 79
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNL-PSEAR---VI 457
+KEI + ++K+ ISVA G+ A ++ L ++AR VI
Sbjct: 80 ENAEVTILAVKPNDMLVVVKEIAPFMN-EDKILISVAAGVPTAAIDGYLGEAKARGRKVI 138
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGP 637
RVMPN A V+E A +G A D ++ ++ A+GT V E MD IT LSGSG
Sbjct: 139 RVMPNIGACVREAVCAICKGKYADEADEEIAKEILSAIGTVHSVNEGDMDVITGLSGSGI 198
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTA 817
A+V +I+++ADG V GLPR+L+L +AAQT +G+A M+ G P+ + SP G+T
Sbjct: 199 AFVATVIDAMADGAVYEGLPRELSLTIAAQTAIGAAKMILEGKQPSEIVTMTASPGGTTI 258
Query: 818 EGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
G Y +E ++A++ AV A R + KQ
Sbjct: 259 RGIYTMESRNVKAAMMEAVIEATRRATEISKQ 290
>UniRef50_Q48P99 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Pseudomonas syringae pv. phaseolicola
(strain 1448A / Race 6)
Length = 284
Score = 137 bits (331), Expect = 6e-31
Identities = 90/278 (32%), Positives = 137/278 (49%), Gaps = 2/278 (0%)
Frame = +2
Query: 89 KLPLIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATAL 268
K P + +I F+G G +A +L G + G+ + + P + G
Sbjct: 9 KDPFMSKTRIAFVGAGNMAASLIGGMRAQGVDAA--LICASAPGAETRERIANDHGIQVF 66
Query: 269 FENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA 448
+N + +K+ A N+L +SVA GIT A++ L +
Sbjct: 67 ADNAEAIKGADVVVLAVKPQMMKNVCQALKSSLEA-NQLIVSVAAGITCASLTQWLGDQP 125
Query: 449 RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALS 625
V+R MPNTP+L+++GA+ K TAE + QL AVG V E MDA+TA+S
Sbjct: 126 -VVRCMPNTPSLLRQGASGLYATDKVTAEQREQAEQLLSAVGVAVWVEQEKHMDAVTAVS 184
Query: 626 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSP 802
GSGPAY ++++E++ GV+ GLP D+A +L QT LGSA + D A L+ VTSP
Sbjct: 185 GSGPAYFFLMMEAMTAAGVKLGLPEDIAKKLTLQTALGSALIATGSDVGAGELRRRVTSP 244
Query: 803 AGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
G+T + GF + + A++AA R + +QL
Sbjct: 245 GGTTEAAIKAFQAGGFEALVETALTAADHRAAELAEQL 282
>UniRef50_Q5KXH0 Cluster: Pyrroline-5-carboxylate reductase; n=13;
Bacillaceae|Rep: Pyrroline-5-carboxylate reductase -
Geobacillus kaustophilus
Length = 299
Score = 136 bits (328), Expect = 1e-30
Identities = 73/173 (42%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +2
Query: 377 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 556
++L +S+ GIT T+E V+R MPNT A V A A + G A E ++ Q
Sbjct: 112 HQLILSLLAGITTETIERLAGRNIPVVRAMPNTSAAVGLSATAIAGGRFAAKEHLEVAKQ 171
Query: 557 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 736
LF+ VG VPE + A+T LSGSGPAYVY L+E++ GL RD+A RL QT +
Sbjct: 172 LFETVGIVAVVPEKDLHAVTGLSGSGPAYVYYLVEAMEKAAADIGLERDVAKRLILQTII 231
Query: 737 GSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
G+A M+K D HP++L+ VTSP G+T G LE+ F+ A+I + A R
Sbjct: 232 GAAEMLKASDKHPSVLRREVTSPGGTTEAGIGVLEQYRFQEAVIACIRRATAR 284
>UniRef50_Q8U084 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Thermococcaceae|Rep: Pyrroline-5-carboxylate reductase -
Pyrococcus furiosus
Length = 261
Score = 136 bits (328), Expect = 1e-30
Identities = 87/271 (32%), Positives = 140/271 (51%), Gaps = 1/271 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MK+ IG G + A+A + E+ A+ + K + G +N
Sbjct: 1 MKVAVIGAGTIGSAVAKALAESNY----EVIATRR--SIEKVKWLEKYGVKLEKDNKKAS 54
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L+EIK ++K+ IS+A GI I ++ + A+ +R MP
Sbjct: 55 READIVIIAVKPNKVGKVLEEIKE--EVESKIVISLAAGIPIKLLKRF--ANAKFVRAMP 110
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N LVKE A++ + E+ + ++F++ G + E MDAIT LSGSGPAYV
Sbjct: 111 NIAVLVKESFTAYAT-EDLSEEEIRTVEKIFESFGKYIRIDEEYMDAITGLSGSGPAYVS 169
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGT 826
+ +E++ GG+R GLPRD+A AAQT LG+A ++ + HPA ++D V +P G+T +G
Sbjct: 170 VFLEAMIYGGLRVGLPRDIAKLAAAQTLLGTAKLLLNFEGHPAEIRDMVITPGGTTIDGI 229
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVKKQLN 919
+ LE+ R+ I+ A+ AA + KI+ +L+
Sbjct: 230 FELEEGKIRTTIMKAIDAATKKSKILSTRLS 260
>UniRef50_Q1FII0 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Clostridium phytofermentans ISDg
Length = 265
Score = 135 bits (327), Expect = 2e-30
Identities = 87/260 (33%), Positives = 123/260 (47%), Gaps = 1/260 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
++E + IGFIG G +A ALANG + + KP +I AS + K + G
Sbjct: 1 MLENITIGFIGFGNMAQALANGLLFKNVVKPRQIYASAKNYEKL-CKNTREKGMIPCKSA 59
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
+ IK L + K+ ISVA G E+ L +
Sbjct: 60 NELVEQCDIIIIAVKPFMVPEVITPIKEL--LQKKIVISVAAGYPFDKYEAILVPGTHHL 117
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGP 637
+PNTP + EG T E+ + LF + + V Q+ LSG GP
Sbjct: 118 STIPNTPVSIGEGIIICENHHSLTKEEYDTVADLFSKIALLEFVDTKQLTVAGTLSGCGP 177
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGST 814
A+V M +E+LADG V+ GLPRD + RLA+Q G+ + ++TG HP +KD V SP G+T
Sbjct: 178 AFVSMFLEALADGAVKHGLPRDTSYRLASQMVAGTGKLQIETGAHPGAMKDAVCSPGGTT 237
Query: 815 AEGTYHLEKNGFRSAIIGAV 874
G LE+ G RSA+I A+
Sbjct: 238 IVGVATLERKGLRSAVIEAI 257
>UniRef50_P22008 Cluster: Pyrroline-5-carboxylate reductase; n=21;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Pseudomonas aeruginosa
Length = 273
Score = 135 bits (326), Expect = 3e-30
Identities = 90/270 (33%), Positives = 138/270 (51%), Gaps = 2/270 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
+I FIG G +A +L G + G+ +I AS P AK G A + E+
Sbjct: 5 RIAFIGAGNMAASLIGGLRAQGVPAA-QIRAS-DPGAEQRAK-IAGEFAIDVVESNAEAV 61
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
A+ + +L +S+A GI A++E+ L V+R MPN
Sbjct: 62 ADADVVVLSVKPQAMKAVCQALAPALKPEQLIVSIAAGIPCASLEAWLGQPRPVVRCMPN 121
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVY 649
TPAL+++GA+ + +A + QL AVG + E Q+DA+TA+SGSGPAY +
Sbjct: 122 TPALLRQGASGLYANAQVSAAQCEQAGQLLSAVGIALWLDDEAQIDAVTAVSGSGPAYFF 181
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGT 826
+L++++ D G + GL R+ A RL QT LG+A M + + PA L+ VTSP G+T
Sbjct: 182 LLMQAMTDAGEKLGLSRETASRLTLQTALGAAQMALSSEVEPAELRRRVTSPNGTTEAAI 241
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
+ NGF + + A++AA R + +QL
Sbjct: 242 KSFQANGFEALVEQALNAASQRSAELAEQL 271
>UniRef50_A2QIA2 Cluster: Catalytic activity: L-proline + NAD(P)(+)
<=> 1-pyrroline-5- carboxylate + NAD(P)H. precursor;
n=8; Pezizomycotina|Rep: Catalytic activity: L-proline +
NAD(P)(+) <=> 1-pyrroline-5- carboxylate + NAD(P)H.
precursor - Aspergillus niger
Length = 286
Score = 134 bits (324), Expect = 4e-30
Identities = 93/278 (33%), Positives = 137/278 (49%), Gaps = 11/278 (3%)
Frame = +2
Query: 92 LPLIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALF 271
+P ++ + F+GGG +A A+ +G + + + I S P +V K LG
Sbjct: 1 MPTLQTSTLAFLGGGNMASAIISGLLRQSVPATN-IHVS-EPWEVNRNK-IAALGVNTTT 57
Query: 272 ENXXXXXXXXXXXXXXXXXXXXPALKEIKN--LPSAKNK--LFISVAMGITIATVESNLP 439
N +E++ +A+ K + +S+A GIT+ +++ L
Sbjct: 58 SNTEAASAADVVILAVKPQVAKTVCEELREEWTATAREKFPIVVSIAAGITLESLQKWLS 117
Query: 440 SE----ARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQ-- 601
E A V+RVMPNTPALV EGA+ G + + ED L L +V E + +
Sbjct: 118 VEGGKVAPVVRVMPNTPALVTEGASGAFAGVEVSKEDKGLVEALLGSVSRVTEWVDKEEL 177
Query: 602 MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAM 778
+D +T LSGSGPAY + ++E L GL ++ A RLAAQT LG+ M V++ D PA
Sbjct: 178 LDVVTGLSGSGPAYFFAMVEHLVASATALGLTKEQATRLAAQTCLGAGKMLVESDDEPAQ 237
Query: 779 LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
L+ NVTSP G+T EK F + AV AA DR
Sbjct: 238 LRKNVTSPNGTTYAALQTFEKLNFADIVDQAVKAATDR 275
>UniRef50_Q0ICK3 Cluster: Pyrroline-5-carboxylate reductase; n=17;
Cyanobacteria|Rep: Pyrroline-5-carboxylate reductase -
Synechococcus sp. (strain CC9311)
Length = 294
Score = 134 bits (323), Expect = 6e-30
Identities = 87/264 (32%), Positives = 129/264 (48%), Gaps = 8/264 (3%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASC---HPSDVASAKAFQGLGATALFENXXX 286
+G IG GR+A AL I L DE+ A H SA+ G+ A ++
Sbjct: 23 LGVIGLGRMAQALVIPLIEQELISADEVIAVVGREHSVATVSARVPSGVKVIAASDSAAE 82
Query: 287 XXXXXXXXXXXXXXXXXPALKEIK----NLPSAKNKLFISVAMGITIATVESNLPSEARV 454
+ P++ + L +SV G+ +A +++ P
Sbjct: 83 HAWAASVQLLAVKPQMLDGVAASAPPPIETPASGSSLLLSVLAGVPLARLQALFPGRI-C 141
Query: 455 IRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSG 634
+R +PNTP LV +G + G + Q F+ V E+PE ++DA AL+ SG
Sbjct: 142 VRAVPNTPCLVGQGLTGLAWGDGISDPQKQQVRSFFEPVSEVLELPEERLDAFLALTSSG 201
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGS 811
PAYV ++ E++ADG V G+PR A LA +T G+AA+++ + HP LKD V SP G+
Sbjct: 202 PAYVALIAEAMADGAVAMGMPRSQAHHLAHRTLAGTAALLQEQELHPGELKDMVASPGGT 261
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAA 883
T HLEK+G RSA+I A+ AA
Sbjct: 262 TMAALRHLEKSGLRSALIEAIVAA 285
>UniRef50_A2EU21 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Trichomonas vaginalis G3|Rep: Pyrroline-5-carboxylate
reductase - Trichomonas vaginalis G3
Length = 269
Score = 134 bits (323), Expect = 6e-30
Identities = 90/264 (34%), Positives = 127/264 (48%), Gaps = 5/264 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I FIG G + A+A + + P EI + A A + + T + N
Sbjct: 4 IAFIGTGNMGGAMAKA--CSKVLDPSEIIITNRTRAKAEEIA-EEIHCTVVNTNVEAVKS 60
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNK----LFISVAMGITIATVESNLPSEARVIRV 463
LKEI N ++ K + +++A G TI+ +S L + +IR+
Sbjct: 61 ATYIVLGVKPQMMEAVLKEIANTVKSERKKRELVILTIAAGKTISFYQSIL-GDIPIIRL 119
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
MPNTP LV EG R KAT E + F G E+PE QMDA +++G G +
Sbjct: 120 MPNTPCLVSEGMTLLVRSPKATDEHVEKVKNFFSKSGLIQEIPESQMDAAGSVAGCGTGF 179
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAE 820
M IE+LADG V G+PR A + AAQ G+A +V ++G HP LKD + SP GST
Sbjct: 180 FCMFIEALADGAVMEGIPRPDAYKYAAQALKGTAELVLQSGKHPGALKDEICSPGGSTIA 239
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDR 892
G LE FR+ ++ AV + R
Sbjct: 240 GVKALEDGKFRATVMEAVLQSTKR 263
>UniRef50_Q02WW5 Cluster: Pyrroline-5-carboxylate reductase; n=12;
Streptococcaceae|Rep: Pyrroline-5-carboxylate reductase
- Lactococcus lactis subsp. cremoris (strain SK11)
Length = 263
Score = 132 bits (319), Expect = 2e-29
Identities = 85/266 (31%), Positives = 136/266 (51%), Gaps = 2/266 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
IGFIG G++A A+ +G EI S H +A + L A +
Sbjct: 4 IGFIGVGKMATAIISGLDKNKF----EIIISGHNLPKTKKQA-EELNVKAAENHEELVQQ 58
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEAR-VIRVMPN 472
L ++ N S K+K IS+A G+T++ ++ SE + +IRVMPN
Sbjct: 59 SDFIVLSVKPQVLPSVLSQLINHLS-KDKTLISIAAGLTLSDLKHLADSENQPIIRVMPN 117
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
A + + +A + ++ ++FKAVG+ E+ E A++GS PA++YM
Sbjct: 118 INAQIGQSTSAIVKNEFVDDSADEIAQEIFKAVGSVHEIAEKDFSTFAAIAGSSPAFIYM 177
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTY 829
I+++A GV GLP+D A + ++T SA M +K+G++P L D V+SP G+T G
Sbjct: 178 FIDAMARAGVLRGLPKDQATAIVSETVKASAEMLLKSGENPWSLVDKVSSPGGTTVAGVV 237
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVK 907
LE+N F +I A+SA ++R K +K
Sbjct: 238 SLEQNHFGGTVIDAISATIEREKYLK 263
>UniRef50_A7GVZ9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Campylobacter curvus 525.92|Rep: Pyrroline-5-carboxylate
reductase - Campylobacter curvus 525.92
Length = 303
Score = 131 bits (316), Expect = 4e-29
Identities = 74/176 (42%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = +2
Query: 368 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 547
+A +FI+VA +I V L ++A+V R MPN P+L+ EG A + + TA+D
Sbjct: 122 NASQPIFITVAPNFSIQMVREVLGADAKVARTMPNMPSLIGEGVTAVNFSSNFTADDRAA 181
Query: 548 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 727
++ G E+ E + TA++GS PAY++M IE+LADG V GL R+ A + +
Sbjct: 182 VMKILSYFGKSYELAEDKFAVFTAIAGSLPAYIFMFIEALADGAVLEGLGREKAYAIVCE 241
Query: 728 TTLGSAAM----VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
GSA M +K G HPA LKD V SP G+T E LE FR+AII AVSAA
Sbjct: 242 AVAGSAKMATAALKEGKHPARLKDEVCSPGGTTIEAVRVLENAKFRAAIIEAVSAA 297
Score = 35.5 bits (78), Expect = 2.8
Identities = 17/30 (56%), Positives = 21/30 (70%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEI 199
MKIGFIGGG + A+ G + AG +PDEI
Sbjct: 1 MKIGFIGGGNMGSAMI-GALVAGSVRPDEI 29
>UniRef50_A1TY17 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Marinobacter|Rep: Pyrroline-5-carboxylate reductase -
Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 277
Score = 131 bits (316), Expect = 4e-29
Identities = 81/271 (29%), Positives = 131/271 (48%), Gaps = 2/271 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I FIG G +A A+ G + +G D I S P D + G + +N
Sbjct: 7 ISFIGAGNMASAIIGGMLDSGFQAGD-IWVSA-PDDGHLQSIRKRFGVSVTTDNRYCAQQ 64
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
++I + L +S+A G+T T+++ L ++RVMPNT
Sbjct: 65 ADIVVLAVKPQVMGDVCRDIAPVVQNTRPLMVSIAAGLTAGTLDTWLGGGLPLVRVMPNT 124
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYM 652
P+LV +GAA ++ + ++F+++G+ V E + ++TALSGSGPAY ++
Sbjct: 125 PSLVGKGAAGLFANSQVKDDQRNAVQKVFESIGSALWVDDENLLHSVTALSGSGPAYFFL 184
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTY 829
++E+L G+ + A LA QT G+A M ++ D P LK NV SP G+T
Sbjct: 185 MLEALESAATEAGIESETARALAIQTMAGAAEMAARSEDDPGQLKRNVMSPGGTTERAIN 244
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 922
E+ G R + A SAA +R + + ++L D
Sbjct: 245 TFEEGGLRDLVKKAYSAAFERSREMSRELAD 275
>UniRef50_Q8EU76 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Oceanobacillus iheyensis|Rep: Pyrroline-5-carboxylate
reductase - Oceanobacillus iheyensis
Length = 270
Score = 130 bits (314), Expect = 7e-29
Identities = 80/260 (30%), Positives = 123/260 (47%), Gaps = 1/260 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQ-GLGATALFENXXXXX 292
I F+G G LA A+ +G A + P+E + SD+ K + G
Sbjct: 5 IAFMGAGSLAEAIISGITKAQIV-PNENILVTNKSDINRLKRIEEGYDIQGNTNKQEVIK 63
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
+L +K +++ ISV G+T +E+ L E VIR MPN
Sbjct: 64 QADIIILAMKPKDAATSLSFMKEY-IRPDQMVISVIAGLTTERMEAILEKEIPVIRTMPN 122
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
T AL+ A A ++G+ T E + QLF+ VG + E M +TA++GSGPA+ Y
Sbjct: 123 TSALIGYSATAIAKGSYVTDEQLAVAEQLFQTVGMTTIIKEKDMHTVTAIAGSGPAFFYY 182
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYH 832
++E++ V GL ++A +L AQT +G+ M++ P L+ N+TSP G+T G
Sbjct: 183 MVEAMEQAAVEAGLDAEMASQLIAQTVIGAGKMLELSGDPITLRKNITSPGGTTEAGVQQ 242
Query: 833 LEKNGFRSAIIGAVSAAVDR 892
L F S + V A +R
Sbjct: 243 LMSEDFASIVQSCVQRARER 262
>UniRef50_Q3Y1B7 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Lactobacillales|Rep: Delta
1-pyrroline-5-carboxylate reductase - Enterococcus
faecium DO
Length = 283
Score = 130 bits (314), Expect = 7e-29
Identities = 81/263 (30%), Positives = 130/263 (49%), Gaps = 2/263 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MK+GFIG G +A A+ +G + G +E+ S + A A + G A N
Sbjct: 16 MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFAAE-TGVHACKSNQEVA 74
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPS-EARVIRVM 466
L+E++ ++ LFIS+A G ++ +E+ L +A ++RVM
Sbjct: 75 SQSDIVLLAVKPKIIEKVLEELREY--SQKVLFISIASGKSLTDLETALEDPQASIVRVM 132
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PN V G +A + AT E Q + +F+A+G+ + E L+GS PA+V
Sbjct: 133 PNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAESDFSTFIGLAGSSPAFV 192
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEG 823
YMLI+++ GV GL + A +AA+ +GS + D +P L D V+SP G+T G
Sbjct: 193 YMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDKNPWELVDQVSSPGGTTVAG 252
Query: 824 TYHLEKNGFRSAIIGAVSAAVDR 892
LE+ GF AII ++ +++
Sbjct: 253 VVALEEAGFIPAIIKGINTTIEK 275
>UniRef50_Q88Z19 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Lactobacillaceae|Rep: Pyrroline-5-carboxylate reductase
- Lactobacillus plantarum
Length = 263
Score = 130 bits (313), Expect = 9e-29
Identities = 83/261 (31%), Positives = 126/261 (48%), Gaps = 2/261 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAF-QGLGATALFENXXX 286
MKIGFIG G + A+ +G++ P +I H + AS + + Q G A N
Sbjct: 1 MKIGFIGAGNMGRAIIDGWLKQQAVVPADIYI--HSAHAASYQPYAQKNGLQACDTNLAV 58
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
ALKE++ + K I++ G+++A + P + V+R+M
Sbjct: 59 AQAADVIVLAVKPNIALAALKEVQ--AALTGKWVITMVSGLSLADYATVAP-DLPVLRIM 115
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PN + G A T E QLF A+G + E +AL+GS PAY+
Sbjct: 116 PNVNVAIGAGMTALVGNDALTPEQYAAGQQLFDAIGATSAIAEKDFPTFSALAGSSPAYI 175
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEG 823
Y I+++A GV+ GL +D A ++AAQ TLGSA V D P L D V+SP G+T G
Sbjct: 176 YFFIDAMARAGVKHGLSKDAATKIAAQATLGSAQNVLASDKIPFDLIDQVSSPGGTTVAG 235
Query: 824 TYHLEKNGFRSAIIGAVSAAV 886
+E+ GF +A++ + A +
Sbjct: 236 LLAMEEAGFMTAVVKGIDATI 256
>UniRef50_P54893 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Deinococci|Rep: Pyrroline-5-carboxylate reductase -
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM
7039)
Length = 261
Score = 130 bits (313), Expect = 9e-29
Identities = 86/263 (32%), Positives = 130/263 (49%), Gaps = 2/263 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M++ F+G G++ ++ G + G +P+E+ + S + + G L
Sbjct: 1 MRLAFVGLGKMGRSILKGALERGFLRPEEVGVLGRTPE-RSRELAEPFGVRPLTR---AD 56
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKL-FISVAMGITIATVESNLPSEARVIRVM 466
PAL A ++L +IS+ GI+ + + L + RV+R M
Sbjct: 57 LGMAERVLIAVQPRDFPALAP----EIAHHRLGYISIMAGISTSVLARRLDNR-RVVRAM 111
Query: 467 PNTPALVKEGAAAFSRGTKAT-AEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
PN ++ E + A + +A AED LF VG E+PE+ DA T +S S PAY
Sbjct: 112 PNLAVVIGESSTALTALKEAREAEDLAFARALFATVGDVYEIPEHLFDAFTGMSASAPAY 171
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEG 823
+ ++ E+LAD GV+ G+PR LALRLAA + ++K G HPA +KD V SP G+T G
Sbjct: 172 LAVVAEALADAGVKMGMPRALALRLAADALAATGELLK-GRHPAQVKDEVASPGGTTIHG 230
Query: 824 TYHLEKNGFRSAIIGAVSAAVDR 892
+ LE R+A AV AA R
Sbjct: 231 LHALEARAVRAAFYEAVEAATRR 253
>UniRef50_Q6KZ51 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Picrophilus torridus|Rep: Pyrroline-5-carboxylate
reductase - Picrophilus torridus
Length = 257
Score = 129 bits (311), Expect = 2e-28
Identities = 86/270 (31%), Positives = 132/270 (48%), Gaps = 2/270 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKI IG G + A+A A D+ D + +++ G G LF+N
Sbjct: 1 MKISIIGAGTIGRAMAE-------ALKDDYEIGLSSRDFSKLESWSG-GRFKLFKNNAEN 52
Query: 290 XXXXXXXXXXXXXXXXP-ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
L EIK+ + KNK+ +S GI I +ES ++ + R M
Sbjct: 53 AAYGDLIILSVKPFNIDDVLNEIKD--NIKNKIIVSFLAGINIDYIESY--AKTSIFRAM 108
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PN P + + A + A ++ +FK G C + E MDA+T LSGSGPA++
Sbjct: 109 PNLPIITGDAITAVAY-KNADENTIKIVDDIFKKTGECIFIDEKSMDAVTGLSGSGPAFI 167
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEG 823
++I+S+ G+R GLPRD A +L +T G+A M KTG P+ ++D V +PAG+ A G
Sbjct: 168 SIMIDSMIVAGIRMGLPRDTARKLTLKTFEGTARLMEKTGLPPSEIRDRVMTPAGTAAAG 227
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+ +E R+ I AV A+ R +K++
Sbjct: 228 VFEIENGNIRTTIARAVEASTKRSMELKRK 257
>UniRef50_Q312A7 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Desulfovibrio|Rep: Pyrroline-5-carboxylate reductase -
Desulfovibrio desulfuricans (strain G20)
Length = 267
Score = 128 bits (310), Expect = 2e-28
Identities = 67/173 (38%), Positives = 102/173 (58%), Gaps = 2/173 (1%)
Frame = +2
Query: 380 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA-TAEDAQLTSQ 556
K+ +S+A G+++ + S A V+RVMPNTPA+V G A +AE A
Sbjct: 89 KVLVSIAAGVSLEAMRSAAQGAAPVVRVMPNTPAMVGRGIYGMCLDDPALSAEAATAVRN 148
Query: 557 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 736
LF A+G +PE + +A TA++G GPAYV+ ++E++ + V G R A + +
Sbjct: 149 LFAAIGKVIVLPEQKFEAFTAVAGCGPAYVFHMMEAVIEAAVTVGFTRQQATEMVTELFS 208
Query: 737 GSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
GS A+ +TG HP++L++ VTSPAG+T GT HL++ R II AV AA ++
Sbjct: 209 GSCALAEQTGIHPSLLREMVTSPAGTTIAGTNHLDRTAVRGHIIDAVLAAYEK 261
>UniRef50_A5UQB8 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Chloroflexi (class)|Rep: Pyrroline-5-carboxylate
reductase - Roseiflexus sp. RS-1
Length = 272
Score = 128 bits (310), Expect = 2e-28
Identities = 83/275 (30%), Positives = 133/275 (48%), Gaps = 2/275 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
++ ++I IG G + A+ +G + L D+I A+ P + Q G +N
Sbjct: 1 MLHHLRIAVIGAGVMGEAMISGLLKQNLIAADQIVAT-EPRAERREEIEQRYGVRVTDDN 59
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
+ E++ + +L IS+A G+ I T L A V+
Sbjct: 60 LEAAHWAQVAIFAVKPQTVSKLMPELRGA-LREGELVISIAAGVPIRTYVQGLAHGA-VV 117
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSG 634
R MPNTPA + EG ++ + + E + + G V E +D TA++G+G
Sbjct: 118 RAMPNTPAQIGEGMTVWTASSAVSEEQRGWARAILGSFGRQMFVDDETYLDMATAINGTG 177
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGS 811
PAY++M++E++ D GV GLPR +A L QT LGS +++ HPA L++ VTSP G+
Sbjct: 178 PAYIFMVLEAMIDAGVHLGLPRYMAEELVLQTMLGSVHYAMQSRRHPAELRNGVTSPGGT 237
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
TA Y LE+ G R+ + A+ AA R + K +
Sbjct: 238 TAAALYELERGGLRTVLSDAIWAAYRRSAELGKMM 272
>UniRef50_Q9KCR6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus halodurans|Rep: Pyrroline-5-carboxylate
reductase - Bacillus halodurans
Length = 279
Score = 128 bits (309), Expect = 3e-28
Identities = 82/268 (30%), Positives = 129/268 (48%), Gaps = 1/268 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
+++ KI F+G G +A ++ G +S L P ++ A+ + K G
Sbjct: 1 MLQDHKITFLGAGSMAESIIAGLLSKKLLLPSQVIATNLCDEAKLTKLEDRYGICTTQNR 60
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
A++EI+ + K +LFISV G T + +E+ L E V+
Sbjct: 61 QEAVRQGTIIFLAMKPKNIEEAIEEIRGEITEK-QLFISVLAGTTTSYIETLLAHEVPVV 119
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGP 637
R MPNT A V A G A A +L + +F A+GT EV E ++DA+T L+GSGP
Sbjct: 120 RTMPNTSAKVGASATGLCGGRYANASHVKLATLIFTAIGTVTEVTEDKLDAVTGLAGSGP 179
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGST 814
AY Y ++E++ V+ GL A +QT +G+ + +T L V SP G+T
Sbjct: 180 AYFYYMVEAMERAAVQSGLTESEAKAFISQTLIGTGKRLEQTSKTAEELYKEVMSPGGTT 239
Query: 815 AEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
G LE+ + AI A++AA++R +
Sbjct: 240 EAGLRVLEQQQMQQAIEEAITAAINRSR 267
>UniRef50_Q8YCL9 Cluster: PYRROLINE-5-CARBOXYLATE REDUCTASE; n=11;
Alphaproteobacteria|Rep: PYRROLINE-5-CARBOXYLATE
REDUCTASE - Brucella melitensis
Length = 300
Score = 127 bits (306), Expect = 7e-28
Identities = 82/238 (34%), Positives = 117/238 (49%), Gaps = 3/238 (1%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
K+ +G G + FA+ G++ +G+ K ++ + A + A +
Sbjct: 33 KVVLVGCGNMGFAMLRGWLDSGILKAGDVHVVEPAEALRERAALAHVHVYADAADLPADL 92
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
L K A F+SVA GI +A ES+L + VIR MPN
Sbjct: 93 QPRMVLVAVKPQMMANVLPAYKRFAPAST--FVSVAAGIPVALFESHLGKDVAVIRCMPN 150
Query: 473 TPALVKEGA-AAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQ-MDAITALSGSGPAYV 646
TPA + +G F + A +A +TS L K G V E MDA+TA+SGSGPAY+
Sbjct: 151 TPAAIGKGMLVTFKNANVSDANEAFVTS-LLKTSGKVASVDEEGLMDAVTAVSGSGPAYI 209
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGSTA 817
+ IE+L D GV GLPR+ A LA QT +G+ A+ D P+ L++ VTSP G+TA
Sbjct: 210 FHFIEALTDAGVNLGLPRETAALLAMQTVMGAGALADASTDSPSKLREQVTSPNGTTA 267
>UniRef50_Q83A21 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Coxiella burnetii|Rep: Pyrroline-5-carboxylate reductase
- Coxiella burnetii
Length = 274
Score = 126 bits (305), Expect = 9e-28
Identities = 84/270 (31%), Positives = 131/270 (48%), Gaps = 2/270 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I FIGGG +A + G I+ G P+ I + D + G +N
Sbjct: 6 ITFIGGGNMARNIVVGLIANGY-DPNRICVTNRSLDKLDFFK-EKCGVHTTQDNRQGALN 63
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
+E+K++ S L IS+A+G+T +E L +R++R MPNT
Sbjct: 64 ADVVVLAVKPHQIKMVCEELKDILSETKILVISLAVGVTTPLIEKWLGKASRIVRAMPNT 123
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYM 652
P+ V+ GA + L + +AVG V E Q++ I ALSGSGPAY+++
Sbjct: 124 PSSVRAGATGLFANETVDKDQKNLAESIMRAVGLVIWVSSEDQIEKIAALSGSGPAYIFL 183
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTY 829
++E+L + + GL ++ A L QT LG+A M ++T L+ VTSP G+T +
Sbjct: 184 IMEALQEAAEQLGLTKETAELLTEQTVLGAARMALETEQSVVQLRQFVTSPGGTTEQAIK 243
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQLN 919
LE R I A++AAV+R K + K ++
Sbjct: 244 VLESGNLRELFIKALTAAVNRAKELSKTVD 273
>UniRef50_Q6N1N9 Cluster: Pyrroline-5-carboxylate reductase; n=23;
Alphaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Rhodopseudomonas palustris
Length = 280
Score = 126 bits (305), Expect = 9e-28
Identities = 90/264 (34%), Positives = 125/264 (47%), Gaps = 3/264 (1%)
Frame = +2
Query: 128 GGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXXXX 307
G G++ AL G+++ GL D + HP++ +A + +G+ A +
Sbjct: 23 GAGKMGGALLTGWLAQGLDGGDVVVIEPHPTEEIAALSARGVRLNASAGDVGAVSTLVVA 82
Query: 308 XXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALV 487
AL+ PS L +S+ G IA + L V+R MPNTPA +
Sbjct: 83 VKPQMFAEAAAALRGYVG-PST---LVVSIMAGKPIAALSEQLGGH--VVRAMPNTPAAI 136
Query: 488 KEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIES 664
G TA + L +A G + V E +DA+TA+SGSGPAYV++L E
Sbjct: 137 GRGITVAVAAGNVTAAQRGIADALLRATGGVEWVDDEALIDAVTAVSGSGPAYVFLLAEE 196
Query: 665 LADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEK 841
LA GV GLP LA+ LA T GS ++ D A L+ NVTSP G+TA L
Sbjct: 197 LARAGVEAGLPEGLAMTLARATVAGSGELLHRSDLDAATLRKNVTSPGGTTAAALEVLMA 256
Query: 842 N-GFRSAIIGAVSAAVDRCKIVKK 910
N GFR + AV+AA R K + K
Sbjct: 257 NDGFRPLLTRAVAAATKRSKELAK 280
>UniRef50_Q6CEN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Yarrowia lipolytica|Rep: Pyrroline-5-carboxylate
reductase - Yarrowia lipolytica (Candida lipolytica)
Length = 299
Score = 126 bits (305), Expect = 9e-28
Identities = 71/180 (39%), Positives = 106/180 (58%), Gaps = 5/180 (2%)
Frame = +2
Query: 374 KNKLFISVAMGITIATVES--NLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 547
+ K+ +S+ G TIA +ES + V+R M NTP+ + G S AT +++ +
Sbjct: 111 EGKVLVSLLAGKTIADIESYSGRCPKPLVVRAMTNTPSRIGAGMTVLSFPDNATVDESVV 170
Query: 548 T--SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 721
S +F+ G C + E QMD TAL GS PA+ +++IE+LADG VR G+P + A + A
Sbjct: 171 NAVSWIFEQTGKCITLEEKQMDVSTALCGSSPAFCFLIIEALADGAVRMGMPYNTAFQCA 230
Query: 722 AQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
AQ+ LG+A M V++G HPA+LK V +P G+T G LE G RS++ AV + + K
Sbjct: 231 AQSMLGAAKMVVESGQHPAVLKSAVCTPGGTTIGGLLALEDKGVRSSVARAVEESTNIAK 290
>UniRef50_Q20848 Cluster: Putative pyrroline-5-carboxylate
reductase; n=2; Caenorhabditis|Rep: Putative
pyrroline-5-carboxylate reductase - Caenorhabditis
elegans
Length = 299
Score = 126 bits (305), Expect = 9e-28
Identities = 91/287 (31%), Positives = 137/287 (47%), Gaps = 16/287 (5%)
Frame = +2
Query: 104 EAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXX 283
E++ FIGGG +A A+ G + G I SA+ ++ LG +F N
Sbjct: 13 ESVPFVFIGGGNMAAAIIKGCQNKGFTPKSNIVIGVQTEK--SAEKWRQLGYKNVFTNTL 70
Query: 284 XXXXXXXXXXXXXXXXXXPALKEIKNLP-SAKNKLFISVAMGITIATVESNLP---SEAR 451
+ + + P +++ + ISV G+ + + + LP
Sbjct: 71 EMLERYSTAIYVICVKPQVFEEVVSSWPVNSRPEFIISVMAGVPLKVLNAKLPFVSGNTT 130
Query: 452 VIRVMPNTPALVKEGAAA--FSRGTKATAEDA--QLTSQLFKAVGTCDEVPEYQMDAITA 619
++R+MPN + + GA+ + + K +D+ +L + + VGT + +PE + A
Sbjct: 131 IVRLMPNVASSIGAGASTMCYEKNEKIMNQDSHIELAREFAECVGTVELIPERCFNPAMA 190
Query: 620 LSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD--------HPA 775
+ GS PA+ +M IESLADG V GL R A RLAAQ LG+A MV + H
Sbjct: 191 IGGSSPAWTFMYIESLADGAVAQGLGRAEAKRLAAQAVLGAAQMVLNSNSGFDIETQHFG 250
Query: 776 MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
LKD V SP G+T EG LEKNGFR A++ AV AA + + K L
Sbjct: 251 SLKDMVCSPGGTTIEGVRALEKNGFRYAVMEAVVAASTKADEMAKSL 297
>UniRef50_A3IBB9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus sp. B14905|Rep: Pyrroline-5-carboxylate
reductase - Bacillus sp. B14905
Length = 267
Score = 126 bits (304), Expect = 1e-27
Identities = 91/264 (34%), Positives = 129/264 (48%), Gaps = 2/264 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGL-GATALFENXXXX 289
KI FIG G +A AL G+I + P EI + + SD Q G +F+
Sbjct: 3 KILFIGAGSMAEALIQGWIKQKVFSPQEIYVT-NRSDKERLHFLQETYGIHCMFDQAIFR 61
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
A++E+K +A++ + +S+ GI I T+ L S V RVMP
Sbjct: 62 QADLIILAMKPKDAIA-AMRELKPKITAQSAI-LSILAGIGIGTITELLGSRP-VARVMP 118
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
NT A + A+ + + + L QL +AVG+ EV E Q+ A+TALSGSGPAY+Y
Sbjct: 119 NTSATIGMSASGIAFNNEVSTAQRILFLQLLEAVGSVIEVEEDQLHAVTALSGSGPAYIY 178
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGSTAEGT 826
L+E+ G GL +D L QT G+A M+K D P +L+ VTSP G+T G
Sbjct: 179 YLMEAFERVGTEVGLSKDTVRLLMTQTLAGTAEMLKQSVDEPDVLRKKVTSPGGTTEAGI 238
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK 898
LE+ F AI + A R +
Sbjct: 239 QALEQYQFNEAIEACIKEAEARSR 262
>UniRef50_Q0VL32 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Alcanivorax borkumensis SK2|Rep: Pyrroline-5-carboxylate
reductase - Alcanivorax borkumensis (strain SK2 / ATCC
700651 / DSM 11573)
Length = 269
Score = 126 bits (303), Expect = 2e-27
Identities = 85/263 (32%), Positives = 131/263 (49%), Gaps = 4/263 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
IGFIG G +A +LA G ++ G+ +P I S PS + Q EN
Sbjct: 6 IGFIGAGNMATSLAGGMVAKGI-RPARIWMS-DPSKDRLDEVAQLQRVHVSTENRDVAGR 63
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
++++L + + L IS+A G+T+ + L S ++R MPNT
Sbjct: 64 VDVLVLAVKPQMMEQVCTDLRDLIAERQPLVISIAAGVTVGNLRRWLGSTP-IVRCMPNT 122
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTC---DEVPEYQMDAITALSGSGPAYV 646
P+LV+ GA + E + ++ +VG DE E ++DA+TA+SGSGPAY
Sbjct: 123 PSLVQAGATGLYAADDVSDEQKAMAKEILGSVGIAFWFDE--EKELDAVTAVSGSGPAYF 180
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEG 823
++L+ESL + GL A ++ QT G+A + T + P +L+ VTSP G+TA
Sbjct: 181 FLLMESLIEAAKAQGLDAGTARQMVLQTAWGAAQLAITSEVGPDVLRQQVTSPGGTTAAA 240
Query: 824 TYHLEKNGFRSAIIGAVSAAVDR 892
E+ GFR + AV+AA +R
Sbjct: 241 LGVFEEAGFREQVQAAVAAARER 263
>UniRef50_Q82X95 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Nitrosomonas|Rep: Delta 1-pyrroline-5-carboxylate
reductase - Nitrosomonas europaea
Length = 270
Score = 124 bits (300), Expect = 4e-27
Identities = 86/265 (32%), Positives = 125/265 (47%), Gaps = 2/265 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKI FIGGG +A A+ G I G + P I A + + + G T
Sbjct: 1 MKITFIGGGNMAGAMIGGLIHHG-STPSHICA-VETDAMRRQQLAEACGVTVTASIPDGI 58
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
+ +NKL IS+A G+ + + L VIR MP
Sbjct: 59 HGSEIVILAVKPQQLRAVANQAAQF--LQNKLVISIAAGVRASDLSQWLNRHEFVIRAMP 116
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYV 646
NTPAL+ EG + + + + +A+GT V E Q+DA+TALSGSGPAYV
Sbjct: 117 NTPALIGEGITGLYALPLVDSRQKEQATTILEAIGTVIWVNEEAQLDAVTALSGSGPAYV 176
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEG 823
+ +E++ + G + GL D A +LA QT LG+ + ++ D A L+ VTS G+T +
Sbjct: 177 FYFLEAMQEAGTQLGLTADTAKQLAMQTFLGATHLAAQSNDTLATLRMKVTSQGGTTEQA 236
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCK 898
+E+ R A I A+ AA DR +
Sbjct: 237 LLSMEQADIRGAFIRAMHAACDRSR 261
>UniRef50_A3LST6 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=5; Saccharomycetales|Rep: Delta
1-pyrroline-5-carboxylate reductase - Pichia stipitis
(Yeast)
Length = 277
Score = 124 bits (300), Expect = 4e-27
Identities = 80/190 (42%), Positives = 107/190 (56%), Gaps = 2/190 (1%)
Frame = +2
Query: 350 EIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT 529
E+K+ + K +L IS+ G TI+ + P V +VM NTPA G A S +A
Sbjct: 92 EVKDSLTGK-QLLISLLAGTTISELTIFTPY---VAKVMTNTPARFGCGTAGISFSPEAE 147
Query: 530 AEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLA 709
A+ L +L VG ++PE MDA TAL GSGPA+ +++ESL DGGVR GLP ++A
Sbjct: 148 AKYEDLVLKLIGTVGEAFKIPEKNMDAATALIGSGPAFCLLMMESLIDGGVRMGLPFEVA 207
Query: 710 LRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAA 883
AA+ G+A MV +TGDHPA LK V +P G+T G +E G R+ I G AA
Sbjct: 208 KLSAAKVMEGTARMVLETGDHPAALKSMVCTPGGTTIGGLLKMEDAGVRAGIARGVEEAA 267
Query: 884 VDRCKIVKKQ 913
V KK+
Sbjct: 268 VISASFAKKK 277
>UniRef50_Q1GJ10 Cluster: Pyrroline-5-carboxylate reductase; n=24;
Alphaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Silicibacter sp. (strain TM1040)
Length = 271
Score = 123 bits (297), Expect = 8e-27
Identities = 91/268 (33%), Positives = 124/268 (46%), Gaps = 4/268 (1%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENX 280
I A + +G G++ A+ G++ GL + +PSD L T + N
Sbjct: 6 IAARGLVLLGCGKMGSAMLKGWLEGGLPREAVYVMDPNPSD--------WLKGTGVHINA 57
Query: 281 XXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIR 460
AL K+ LFISVA G I+T E+ L ++R
Sbjct: 58 TVPEQPAIVLVAVKPQVMGAALPSAKSYGGG-GTLFISVAAGTPISTFETMLGESTPIVR 116
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGP 637
MPNTPA V G A L +AVG + E QMDA+T +SGSGP
Sbjct: 117 AMPNTPAAVGRGITALIGNAHVDEAKMAQADALLQAVGQTVRLDDEGQMDAVTGVSGSGP 176
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGST 814
AYV+ LIE+LA GV GLP LA++LA T G+ A+ + + P+ L+ NVTSP G+T
Sbjct: 177 AYVFHLIETLAAAGVAQGLPEPLAMQLAKATVAGAGALAEAAEEDPSALRVNVTSPNGTT 236
Query: 815 AEGTYHL--EKNGFRSAIIGAVSAAVDR 892
L E+ GF + AV+AA R
Sbjct: 237 QAALEVLMDEETGFPPLLQRAVAAAAKR 264
>UniRef50_A5CND2 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Actinobacteria (class)|Rep: Pyrroline-5-carboxylate
reductase - Clavibacter michiganensis subsp.
michiganensis (strain NCPPB 382)
Length = 291
Score = 123 bits (297), Expect = 8e-27
Identities = 71/173 (41%), Positives = 95/173 (54%), Gaps = 1/173 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L ISVA G+TIAT ES LP+ V+R MPNTP+LV G + GT++ E L +F
Sbjct: 114 LVISVAAGVTIATFESLLPAHVAVLRSMPNTPSLVGRGVTGLAAGTRSGPEHLALARAVF 173
Query: 563 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
VG EVPE ++DA++ +SGSGPAYV++LIE L G D A L T G+
Sbjct: 174 ATVGDVVEVPEERIDALSTISGSGPAYVFLLIEELTRTAKAKGFSPDEARVLVQGTFRGA 233
Query: 743 AAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
++ +GD PA L+ VTSP G+T L+ A AA+ R +
Sbjct: 234 VELLAVSGDEPAELRRRVTSPNGTTERAVQVLQAADLSGLFDRATDAALARAR 286
>UniRef50_Q8DJK6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Synechococcus elongatus|Rep: Pyrroline-5-carboxylate
reductase - Synechococcus elongatus (Thermosynechococcus
elongatus)
Length = 273
Score = 122 bits (295), Expect = 1e-26
Identities = 88/262 (33%), Positives = 121/262 (46%), Gaps = 3/262 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCH-PSDVASAKAFQGLGATALFENXXXXX 292
+G IG GR+A A+ ++ GL PD + S P G+ T E
Sbjct: 13 LGIIGCGRMAEAMLARLLAKGLL-PDHVWVSARSPQRQQYLAHTYGVRVTTNLEVATAET 71
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNK-LFISVAMGITIATVESNLPSEARVIRVMP 469
E+ + P A+ + +S+ GI + P + R MP
Sbjct: 72 LLLAVKPQVLADIE----SELADTPVAQEMGVVLSIMAGIHSGRLRRLFPQRL-IFRAMP 126
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
NTPA V G A + + A+ + Q L +G V E QMDA+TALSGSGPA+V
Sbjct: 127 NTPAQVGAGVIALASDSAASELEIQKIKNLLGVLGQVVAVSEGQMDAVTALSGSGPAFVA 186
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGT 826
+++E+L D GV GL R L L T G+ ++K G HPA LKD V SPAG+T G
Sbjct: 187 LIVEALCDAGVAVGLSRSLTQELVYGTIAGTVQLLKERGLHPAQLKDAVASPAGTTIAGL 246
Query: 827 YHLEKNGFRSAIIGAVSAAVDR 892
LE G R ++ V AA +R
Sbjct: 247 EVLEAAGMRGTLMQTVKAAYER 268
>UniRef50_A6GTV0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Limnobacter sp. MED105|Rep: Pyrroline-5-carboxylate
reductase - Limnobacter sp. MED105
Length = 268
Score = 122 bits (294), Expect = 2e-26
Identities = 85/268 (31%), Positives = 131/268 (48%), Gaps = 5/268 (1%)
Frame = +2
Query: 122 FIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXX 301
FIGGG +AFA+ G I +G++ PS A+AK + L
Sbjct: 6 FIGGGNMAFAILGGLIGSGVSASTFHVVD--PSPEAAAKM------STLNIQCTTDWPSD 57
Query: 302 XXXXXXXXXXXXPALKEIKNLPSA--KNKLFISVAMGITIATVES-NLPSEARVIRVMPN 472
++ + N +A L IS+A G+++A +++ + ARV+R MPN
Sbjct: 58 FTPEIVVLAVKPQMMQSVLNNQAAHLSRALIISIAAGVSVAQIQNWSQQGNARVVRCMPN 117
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEY-QMDAITALSGSGPAYVY 649
TPALV +G + + + ED + Q+F + G + E +++A+TA+SGSGP YV+
Sbjct: 118 TPALVSQGISGLFFTSNCSVEDRNIAQQIFSSCGEVLVLNEEDEINAVTAISGSGPGYVF 177
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHP-AMLKDNVTSPAGSTAEGT 826
L+E+LA+ G A L +QT LG+A + K D A L++ VTS G+T G
Sbjct: 178 FLMEALAEAAKNLGFNESQANLLVSQTFLGAATLAKQSDDSFATLREKVTSKGGTTFAGL 237
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
L G + AI A AA R ++K
Sbjct: 238 EQLRALGVQDAIKSAAKAACTRAVELQK 265
>UniRef50_A6DTF8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Lentisphaera araneosa HTCC2155|Rep:
Pyrroline-5-carboxylate reductase - Lentisphaera
araneosa HTCC2155
Length = 266
Score = 122 bits (294), Expect = 2e-26
Identities = 84/262 (32%), Positives = 131/262 (50%), Gaps = 2/262 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
++ FIG G++A A+A G G+ +EI + P S F+ L + ++
Sbjct: 3 ELSFIGTGKMASAIAKGICLNGVLTSEEIIGTA-PDQ--SRFDFRDLTNIPVSDDNAEAM 59
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
+ ++ P K++ F+S+ GIT+ +E L ++ +V R MPN
Sbjct: 60 NSRMVVLAFKPQVAEQICRSLQ--PMVKDQYFVSICAGITLDNLEQWLGTD-KVTRTMPN 116
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
TP V +GA A+ + D L +Q F+ G +V E ++ ITALSGSGPAYV+
Sbjct: 117 TPLCVSKGAVAYCSASGVGESDLALLTQYFECSGILAKVAEDDINTITALSGSGPAYVFE 176
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV--KTGDHPAMLKDNVTSPAGSTAEGT 826
+I++LA GL ++AL + QT LGSA M+ K G P L++ VTSP G+T
Sbjct: 177 MIDALAQSAKANGLSDEVALAFSIQTFLGSAQMLSDKLGT-PEELRNAVTSPNGTTYAAL 235
Query: 827 YHLEKNGFRSAIIGAVSAAVDR 892
+ ++N R + AA DR
Sbjct: 236 ENFKQNNLREVLHQGFQAAKDR 257
>UniRef50_Q9HLT6 Cluster: Pyrroline-5-carboxylate reductase related
protein; n=2; Thermoplasma|Rep: Pyrroline-5-carboxylate
reductase related protein - Thermoplasma acidophilum
Length = 279
Score = 122 bits (294), Expect = 2e-26
Identities = 79/268 (29%), Positives = 131/268 (48%), Gaps = 1/268 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I IG G + A++ AG I+ P A KA+ G T +N
Sbjct: 14 IAVIGAGTIGSAISISLAKAGY---HVISTRRRPDLNAGLKAY---GITVTSDNVQAVTS 67
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
+K++ + + K+ +S+A + I + LP + ++R M N
Sbjct: 68 ADMVILTLKPADLVSEMKKLSQI--LEGKIVVSMAAAVPIRVIRHILP-RSFIVRSMTNI 124
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYML 655
A V G F + + S++ G + V E MDA+TALSGSGPAY+ +
Sbjct: 125 AAEVNAGYTPFCTLEEDEGK-ISFVSRVLGVFGETERVDEKYMDALTALSGSGPAYILTI 183
Query: 656 IESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYH 832
IE++ GG++ GLPR +AL+ + QT +GSA ++ +GDHP+ +K+ V +P G T +G Y
Sbjct: 184 IEAMMYGGLKVGLPRSIALKASYQTVMGSAKLLAMSGDHPSAIKEKVITPGGVTIDGIYE 243
Query: 833 LEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
LE R++I+ A+ ++ + + + K L
Sbjct: 244 LENGKIRTSIMKAIESSTLKARKISKDL 271
>UniRef50_A3H628 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Caldivirga maquilingensis IC-167|Rep:
Pyrroline-5-carboxylate reductase - Caldivirga
maquilingensis IC-167
Length = 187
Score = 122 bits (294), Expect = 2e-26
Identities = 70/178 (39%), Positives = 99/178 (55%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
ISV G++ + S ++ARVIR MPN L G A SRG +AT D + T LF A
Sbjct: 2 ISVVAGLSTKLLGSL--TKARVIRTMPNISILEGSGVTAVSRGPRATDADVEFTCSLFNA 59
Query: 569 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 748
VG C V E ++A+TALSGSGPAYV M++E+L + G+ GLP DLA L+ + S A
Sbjct: 60 VGKCYIVNEEYLNAVTALSGSGPAYVAMIVEALWEAGILIGLPSDLAWSLSID-VIESGA 118
Query: 749 MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 922
+ P + +V +P G T G E+ G + ++G + +A R V+K + D
Sbjct: 119 KLLNSKKPWEIISDVATPGGVTISGIKFAEERGLKGLLMGMIESAYRRSTDVQKTIED 176
>UniRef50_Q12740 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Ascomycota|Rep: Pyrroline-5-carboxylate reductase -
Zalerion arboricola
Length = 320
Score = 121 bits (292), Expect = 3e-26
Identities = 65/157 (41%), Positives = 94/157 (59%), Gaps = 1/157 (0%)
Frame = +2
Query: 449 RVIRVMPNTPALVKEGAAAFSRGTKA-TAEDAQLTSQLFKAVGTCDEVPEYQMDAITALS 625
+V+R MPNT + ++E + + +A + L + +FK +G ++P MDA TAL
Sbjct: 156 QVVRAMPNTASGIRESMTVIATSSPPLSATTSSLITWIFKRIGDVVQLPAATMDASTALC 215
Query: 626 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPA 805
GSGPA+ +++E+ DG V GLPR A R+AAQT G+A +V +G+HPA+LKD VT+P
Sbjct: 216 GSGPAFFALILEAAIDGAVAMGLPRAEAQRMAAQTMKGAAGLVLSGEHPALLKDKVTTPG 275
Query: 806 GSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
G T G LE+ G R G V+ AV +V QL
Sbjct: 276 GCTIGGLMVLEEGGVR----GTVARAVREATVVASQL 308
>UniRef50_Q0C2D9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Hyphomonas neptunium ATCC 15444|Rep:
Pyrroline-5-carboxylate reductase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 268
Score = 121 bits (291), Expect = 4e-26
Identities = 72/171 (42%), Positives = 99/171 (57%), Gaps = 3/171 (1%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
IS+ G+ +A + L +E RVIR MPNTP + +G F+ A D +L
Sbjct: 90 ISIMAGVRLAQLSRRLGTE-RVIRSMPNTPGAIGQGVTVFTAPEGAKRTDLSAARELLAP 148
Query: 569 VGTCD-EVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 745
+G V E M A+TALSGSGPAY+++L E +A+ GV GLPRDLAL LA +T G+A
Sbjct: 149 LGEVHGPVDEAMMSAVTALSGSGPAYIFLLAEVMAEAGVAQGLPRDLALSLARRTVEGAA 208
Query: 746 AMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAAVDR 892
A++ ++GD P L+ VTSP G+T L G A+ A+SAA +R
Sbjct: 209 ALMGESGDSPEALRKAVTSPGGTTQAALDILMDTGGMPALFRNALSAAANR 259
>UniRef50_A1AVF5 Cluster: Pyrroline-5-carboxylate reductase; n=2;
sulfur-oxidizing symbionts|Rep: Pyrroline-5-carboxylate
reductase - Ruthia magnifica subsp. Calyptogena
magnifica
Length = 286
Score = 121 bits (291), Expect = 4e-26
Identities = 79/271 (29%), Positives = 128/271 (47%), Gaps = 2/271 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
IGFIG G +A+A+ +G I+ G+ K ++I S + S + + +N
Sbjct: 17 IGFIGAGNMAYAIISGLINNGI-KHNQIKISDTNKALLSLRKTE-FNLEVFTDNTKLAIQ 74
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
K++KN A N L IS+A G+ +E L ++R MPN
Sbjct: 75 CNVIVLAVKPQVLSSVCKDLKN-KLAINTLIISIAAGVRSRDIERWLGDNQAIVRTMPNM 133
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYM 652
PAL+ +G + + + L + +VG C V E +D ITA+SGSGPAY ++
Sbjct: 134 PALLNQGITGLFANKQVSDKQKSLAENILNSVGECLWVNDEGLLDVITAVSGSGPAYFFL 193
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGSTAEGTY 829
++ES+ G GL +A +L+ QT LG++ + + D P L++ VTS G+T
Sbjct: 194 MLESMTKVGAALGLDEAVAQKLSIQTALGASIVASSSEDSPQQLRNKVTSKNGTTQAAIE 253
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 922
+ F I A+ AA +R + +L +
Sbjct: 254 SFQDQDFEVIIAHAMRAAFNRANEIGMELGN 284
>UniRef50_Q9CPE8 Cluster: Pyrroline-5-carboxylate reductase; n=93;
Proteobacteria|Rep: Pyrroline-5-carboxylate reductase -
Pasteurella multocida
Length = 275
Score = 121 bits (291), Expect = 4e-26
Identities = 85/274 (31%), Positives = 132/274 (48%), Gaps = 4/274 (1%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFE-N 277
++A I FIGGG +A A+ G + G ++IT S + A +G+ + +
Sbjct: 1 MQAKSICFIGGGNMAQAIIFGLLKQGYPA-NQITVSDPNAAKRQCLAEKGVNTVEASQTD 59
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
A+ + + KL IS+A G+++ ++S LP+ +++
Sbjct: 60 TQDAVETSEVLLLAVKPQMIAAVCQGLSAVDFSQKLVISIAAGVSVTKLQSRLPTAKQIV 119
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSG 634
RVMPNTPALV EG + E Q T L AVG TC E M ITA SGS
Sbjct: 120 RVMPNTPALVAEGMSGLFAQNSLKPEYKQFTQDLLNAVGKTCWVTQEADMHTITAGSGSS 179
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHP-AMLKDNVTSPAG 808
PAY ++ +E++ + + D A L Q+ LG+A MV + D P A L++NVTS G
Sbjct: 180 PAYFFLFMEAMQQALCQMNMDEDTARLLVQQSALGAAKMVIENPDLPIATLRENVTSKGG 239
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
+TA L + + + A+ A V+R + ++K
Sbjct: 240 TTAAALQVLNQQQLQHIVQQAMQACVERSQQMEK 273
>UniRef50_Q1AVY1 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
Pyrroline-5-carboxylate reductase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 262
Score = 120 bits (290), Expect = 6e-26
Identities = 86/264 (32%), Positives = 125/264 (47%), Gaps = 2/264 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITAS-CHPSDVASAKAFQGLGATALFENXXXX 289
++G IG G++ +L + +G E+ S HP V + + + + N
Sbjct: 3 RVGVIGAGKIGGSLLSRLAESG---DFELAVSDVHPEQVERFRRYDRVRPAS--SNLELA 57
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L+EI + + SVA G+ I T+ES LP V+RVMP
Sbjct: 58 EASEIVIVAVKPWDVAGVLEEISPAMGSGGRSVTSVAAGVEIRTIESYLPEGTPVLRVMP 117
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N A V GAA + ++ +F VG E+PE DA TAL GSGPAYV
Sbjct: 118 NVCASVGLGAAVITANEPGRRVLPEVMD-IFGRVGEVMELPERLFDAATALHGSGPAYVA 176
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGT 826
+ ++L GVR GLPR++A RL T G+A ++K D A ++D V +P G+TA
Sbjct: 177 LFADALIQAGVREGLPREVARRLVVGTLAGTAVLLK--DRSAHQVRDEVMTPGGTTAAAF 234
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK 898
+EK GF A+ V+AA R +
Sbjct: 235 VAMEKAGFVGAVYDGVNAATRRAR 258
>UniRef50_A1H9S1 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Burkholderiales|Rep: Pyrroline-5-carboxylate reductase -
Ralstonia pickettii 12J
Length = 349
Score = 120 bits (290), Expect = 6e-26
Identities = 82/269 (30%), Positives = 124/269 (46%), Gaps = 2/269 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
+++ +K+GFIGGG +A AL G I+ G + + P++ A ++A A
Sbjct: 76 MLDTLKLGFIGGGNMAAALIGGLIAKGAHSANIVVVD--PTEPARSRAEHTWAARTAAAP 133
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
++ P + L +SVA GI I + L ARV+
Sbjct: 134 GAELADRDVIVLAVKPQQMREVCAQLA--PHLGDSLVLSVAAGIRIQDLSRWLNGHARVV 191
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSG 634
R MPNTPAL G + + D S + AVG VP E Q+DA+TA+SGSG
Sbjct: 192 RAMPNTPALSGLGMTGLAANAGLSDADRATASAIANAVGKSVWVPAEAQIDAVTAISGSG 251
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGS 811
PAYV+ IE++ GL + LA +T +G+A + P +L++ VTS G+
Sbjct: 252 PAYVFYFIEAMQQAAQELGLSAEDGRTLAVETFIGAATLAGQSSEPVEVLRERVTSKGGT 311
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
T +E ++A + A+ AA R K
Sbjct: 312 TYAALTSMEGADIKAAFVRAMHAAAARGK 340
>UniRef50_Q0EXW9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Mariprofundus ferrooxydans PV-1|Rep:
Pyrroline-5-carboxylate reductase - Mariprofundus
ferrooxydans PV-1
Length = 268
Score = 120 bits (289), Expect = 8e-26
Identities = 88/270 (32%), Positives = 137/270 (50%), Gaps = 4/270 (1%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENX 280
++ + I FIGGG +A AL G AG A E+ P++ + G +N
Sbjct: 1 MQQLTISFIGGGNMAEALIAGLRRAGHAA--ELICVAEPTEARRQQLSSIYGVRTTADNV 58
Query: 281 XXXXXXXXXXXXXXXXXXXPALKEI-KNLPSAKNKLFISVAMGITIATVESNLPSE-ARV 454
AL + ++L + + +S+A G++I+++ L + A +
Sbjct: 59 EAVSCADMLVLAVKPQQMKNALSGMGEHLKT--DATIVSIAAGVSISSLAEWLSGKSANL 116
Query: 455 IRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGS 631
+RVMPNTPALV EG + + A E + L +A G + V E QM A+TA+SGS
Sbjct: 117 VRVMPNTPALVGEGMSVLY--SDAGDEHHNRATYLMQACGAVEWVDSEQQMHAVTAVSGS 174
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAG 808
GPAY ++L E + GV GL +LA +LAAQT LG+ M+ ++G P +L+ VTSP G
Sbjct: 175 GPAYFFLLAEVMRASGVALGLSEELAGKLAAQTALGAGRMLAESGRTPEILRQQVTSPGG 234
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
+T + + G + + A++AA R K
Sbjct: 235 TTQAALDVMFEEGLPATVRKALAAASKRSK 264
>UniRef50_A3HTL9 Cluster: Putative pyrroline-5-carboxylate
reductase; n=1; Algoriphagus sp. PR1|Rep: Putative
pyrroline-5-carboxylate reductase - Algoriphagus sp. PR1
Length = 267
Score = 120 bits (288), Expect = 1e-25
Identities = 80/272 (29%), Positives = 125/272 (45%), Gaps = 1/272 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
++ KI IG G L ++ANG + +T + + S F+ GA +N
Sbjct: 1 MLSTQKIAIIGCGNLGSSIANGLLEKESFDAKNLTLT--KRNTISLSDFEARGAHVHSDN 58
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
P LKEIK + K ++ IS+A GI++A + L S+
Sbjct: 59 VMAAKYADIILLGVKPYNVAPLLKEIKPVLDPKKQVIISLATGISLAEMYEVLDSKTVTF 118
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGP 637
R MPN A ++E + A+ + ++ QLF ++G ++ E M+A T L G
Sbjct: 119 RAMPNIAADIQESITCVCQ-QGASLKQIEIIKQLFDSIGITIDIDEKLMEAATVLGACGI 177
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGST 814
AYV + ++ GG++ G A R+ QT G+A M++ HP D VT+P G T
Sbjct: 178 AYVLRFMRAMIQGGIQIGFDSKTASRIVNQTVKGAAELMIQQNTHPEEAIDKVTTPKGCT 237
Query: 815 AEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
G +E GF SA++ V A+ + KI KK
Sbjct: 238 IVGLNEMEHQGFSSAMVRGVIASFE--KIEKK 267
>UniRef50_Q89DI5 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=10; Alphaproteobacteria|Rep: Delta
1-pyrroline-5-carboxylate reductase - Bradyrhizobium
japonicum
Length = 292
Score = 119 bits (286), Expect = 2e-25
Identities = 84/264 (31%), Positives = 127/264 (48%), Gaps = 3/264 (1%)
Frame = +2
Query: 128 GGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXXXX 307
G G++ A+ G+++ GL H + SA A +G+ AL +
Sbjct: 35 GAGKMGGAMLTGWLAGGLDPRRVAVVDPHIAPEISALAAKGV---ALNPDAKAAGQVETM 91
Query: 308 XXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALV 487
A ++K S K + +S+ G TIA+++ V+R MPNTPA +
Sbjct: 92 VVAVKPQMFREAGAKLKPFVSEKTSV-VSIMAGTTIASLQE--VCGGAVVRAMPNTPAAI 148
Query: 488 KEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIES 664
G + + L +A G+ + V E MDA+TA+SGSGPAYV++L E
Sbjct: 149 GRGITVAVAAKNVSTAQRAVADALLRATGSVEWVEDESLMDAVTAVSGSGPAYVFLLAEE 208
Query: 665 LADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGT-YHLE 838
LA GV GLP LA +LA +T GS ++ + P+ L+ NVTSP G+TA +
Sbjct: 209 LARAGVEAGLPEALATKLARETVAGSGELLHQSELPSGTLRQNVTSPGGTTAAALGVLMG 268
Query: 839 KNGFRSAIIGAVSAAVDRCKIVKK 910
+ G R +I A++AA R K + K
Sbjct: 269 EPGLRDLMIRAIAAATQRSKELAK 292
>UniRef50_A1IB74 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
Pyrroline-5-carboxylate reductase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 280
Score = 119 bits (286), Expect = 2e-25
Identities = 84/273 (30%), Positives = 124/273 (45%), Gaps = 7/273 (2%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSD-VASAKAFQGLGATALFENXXXXX 292
+GFIGGG +A A+ G ++AG+ + + A+ D +A K G+ T +N
Sbjct: 8 VGFIGGGNMAEAMIGGLLAAGVCEASRVHAADVSRDRLAYLKTTFGIHTTG--DNCAVVD 65
Query: 293 XXXXXXXXXXXXXXXPALKEIKNL--PSAKNKLFISVAMGITIATVESNLPSEA--RVIR 460
L + P KL I++A GI + T+E L S V+R
Sbjct: 66 GCDVLVLAVKPQVMGSVLSTLDAGCGPRLSKKLVITIAAGIPVQTIEGMLASAPGLAVVR 125
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGP 637
MPNTPALV G T+ D + +A G E E +DA+TA+SGSGP
Sbjct: 126 AMPNTPALVGCGMCGMYANPHVTSADRGHARAILEATGRVIEFETEALLDAVTAVSGSGP 185
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA-MVKTGDHPAMLKDNVTSPAGST 814
AYV+ +E++ G GL A + QT G+ M + G+ P L+ VTSP G+T
Sbjct: 186 AYVFYFVEAMVKAGENLGLDTKDAFAMTLQTVKGAVTLMEERGESPKELRQKVTSPGGTT 245
Query: 815 AEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
L + F ++ A+ AA R + +Q
Sbjct: 246 EAALRVLREKEFPEIVMTAIEAACQRAGELSRQ 278
>UniRef50_P27771 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Treponema pallidum|Rep: Pyrroline-5-carboxylate
reductase - Treponema pallidum
Length = 263
Score = 119 bits (286), Expect = 2e-25
Identities = 88/266 (33%), Positives = 129/266 (48%), Gaps = 7/266 (2%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQ-GLGATALFENXXX 286
M +GF+G G + ALA G + AG + ++ A + A+ G+GA A +
Sbjct: 1 MNVGFLGFGAMGRALAEGLVHAGALQAAQVYACALNQEKLRAQCTSLGIGACASVQELVQ 60
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA----RV 454
+++ S + K+ IS+A G++ A E+ ++ R
Sbjct: 61 KSEWIFLAVKPSQISTV-----LRDRQSFQGKVLISLAAGMSCAAYEALFAADPHQGIRH 115
Query: 455 IRVMPNTPALVKEGAA-AFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGS 631
+ ++PN P V G A +R T E A L + L + V + V ++G
Sbjct: 116 LSLLPNLPCQVARGVIIAEARHTLHHDEHAALLAVL-RTVAQVEVVDTAYFAIAGVIAGC 174
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAG 808
PA+ IE+LAD GVR GL RD A RLAA G+AA+++ +G HPA LKD V SPAG
Sbjct: 175 APAFAAQFIEALADAGVRYGLARDQAYRLAAHMLEGTAALIQHSGVHPAQLKDRVCSPAG 234
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAV 886
ST G LE+ G R A+I AV AA+
Sbjct: 235 STIRGVLALEEQGLRRAVIHAVRAAL 260
>UniRef50_Q3MCP7 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=5; Nostocaceae|Rep: Delta 1-pyrroline-5-carboxylate
reductase - Anabaena variabilis (strain ATCC 29413 / PCC
7937)
Length = 314
Score = 118 bits (284), Expect = 3e-25
Identities = 81/288 (28%), Positives = 132/288 (45%), Gaps = 5/288 (1%)
Frame = +2
Query: 44 WSNAVEFARDVLYVRKL---PLIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCH 214
W +EF ++Y++K+ ++ +KI FIGGG + + + +S + E+
Sbjct: 18 WGEVIEFT--LIYLKKIRGAAMLGDLKIAFIGGGTMGEMIISRLLSTKTVEKSELIIVSE 75
Query: 215 PSDVASAKAFQGLGATALFENXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFIS 394
P + G N + +K+ + L IS
Sbjct: 76 PYSTRCLYLEKEYGVHTTNCNIEAVQGASIVILAVKPQVLPEVMAVLKD-QIPPDALVIS 134
Query: 395 VAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG 574
+ G +++++ L + V+R MPN V G +S + T T + +A+G
Sbjct: 135 IVGGASVSSLCQGL-NHGAVVRTMPNIAVQVGHGTTVWSASSNVTEIQRSHTQIILQALG 193
Query: 575 TCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA- 748
E+ +D TALS +G +V++ IE++ D GV+ GL R A L T GS
Sbjct: 194 KEFVTQNEHYLDMATALSSAGTGFVFLYIEAMIDAGVQMGLTRIQAQELTLHTIAGSVEL 253
Query: 749 MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
M++T +HPA+L++ VTSP G TA G Y LEK G R++I A S A+ R
Sbjct: 254 MLQTNEHPAVLRNKVTSPGGVTAAGIYELEKGGMRTSISNAFSTALSR 301
>UniRef50_Q1UAB2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Lactobacillus reuteri|Rep: Delta
1-pyrroline-5-carboxylate reductase - Lactobacillus
reuteri 100-23
Length = 257
Score = 118 bits (283), Expect = 4e-25
Identities = 63/168 (37%), Positives = 97/168 (57%), Gaps = 1/168 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
+FIS A GIT A + LP++ ++ ++PNTP V G + T +AE +
Sbjct: 87 IFISAAAGITHADLAKVLPNK-EIVNIIPNTPVEVNAGTIGLALPTGISAEAISKVMTVL 145
Query: 563 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
++G EVPE Q+D I + G GPA+V +++++++D V+ GL R A + A G+
Sbjct: 146 DSLGDVIEVPERQLDIIGVIGGCGPAFVDVMMDAMSDAAVKHGLDRQTAYEVIASMVKGT 205
Query: 743 AAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
+ PA+L+D VTSPAG+T +G LEKNGFR A++ AV+ A
Sbjct: 206 GTLAYDSKLAPALLRDQVTSPAGTTIKGVEALEKNGFRYALMDAVNKA 253
>UniRef50_A3UFN9 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Hyphomonadaceae|Rep: Pyrroline-5-carboxylate reductase -
Oceanicaulis alexandrii HTCC2633
Length = 282
Score = 117 bits (282), Expect = 5e-25
Identities = 85/267 (31%), Positives = 129/267 (48%), Gaps = 7/267 (2%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFI--SAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXX 286
+IG +G GR+ ALA+G++ S G D+I V + + G +
Sbjct: 7 RIGLLGAGRMGSALASGWLRKSRGGVSADQIVLIDPRPGVGAQGLMESHGVKCVPALTGQ 66
Query: 287 XXXXXXXXXXXXXXXXXPAL--KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIR 460
++ K ++LP + L IS+A G+ + T+ + LP ++R
Sbjct: 67 IAATLDTLVVAIKPDLVRSVLGKVSEDLP--EGALVISIAAGVPLRTLSAALPGRP-IVR 123
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDA-QLTSQLFKAVGTCDEVP-EYQMDAITALSGSG 634
MPNTPA + EG + A + + +L K G + + E MDA+TA+SGSG
Sbjct: 124 AMPNTPAAIGEGVSVCVANEAADTKTLIRQAERLLKPAGLVEWISDERMMDAVTAVSGSG 183
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGS 811
PAYV++ E+LA GL R+LA+ LA QT +G+ AM+K G P L+ NVTSP G+
Sbjct: 184 PAYVFLFTEALAAAAEAEGLSRELAMTLAKQTVIGAGAMMKAGLGEPDELRRNVTSPNGT 243
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDR 892
T G L G ++ AA +R
Sbjct: 244 TQAGLDALMSGGGLPGLVRNAVAAAER 270
>UniRef50_Q1YVF3 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - gamma proteobacterium HTCC2207
Length = 271
Score = 117 bits (281), Expect = 7e-25
Identities = 78/262 (29%), Positives = 124/262 (47%), Gaps = 2/262 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KI FIGGG +A ++ G ++ G +P++I ++ + Q G A +N
Sbjct: 3 KIAFIGGGNMASSIIGGMLANGF-QPEQICVGNRGTEKCQ-RLQQAYGIAATSDNHAAVA 60
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
+K++ + + + +SVA GI + + L + ++RVMPN
Sbjct: 61 GADIVVMAVKPQVMGAVVKDLASSINP-GAVVVSVAAGIQLCNFQDWLGASRAIVRVMPN 119
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVY 649
TP++V+ GAA + E +F AVG +C E Q+DA+TA+SGSGPAY +
Sbjct: 120 TPSMVRCGAAGLFANALVSNEQKVSIESIFNAVGISCWVDNEAQIDAVTAVSGSGPAYFF 179
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGT 826
+ +E++ G GL +A L QT LG+A M +H L+ V+SP G+T
Sbjct: 180 LFMETMQRVGQELGLSEQVARELTIQTALGAAEMASNSEHNTEELRLQVSSPGGTTRAAI 239
Query: 827 YHLEKNGFRSAIIGAVSAAVDR 892
E I A+ AA +R
Sbjct: 240 AQFEALDIEETIRQAMRAAHNR 261
>UniRef50_Q9PA08 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Xylella fastidiosa
Length = 305
Score = 116 bits (280), Expect = 9e-25
Identities = 70/186 (37%), Positives = 100/186 (53%), Gaps = 3/186 (1%)
Frame = +2
Query: 362 LPSAKNK-LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED 538
LP N L IS+A GIT ++ L ++R MPNTPAL+ G + TA
Sbjct: 113 LPVQPNTPLVISIAAGITTCKLKHWLGDTCAIVRAMPNTPALLGAGVTGLFATSHTTATQ 172
Query: 539 AQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 715
L +LF +VG T E MDA+TA+SGSGPAY ++L E++ + GL A
Sbjct: 173 RTLAEELFNSVGKTLWITEEALMDAVTAVSGSGPAYAFLLAEAMEAAAIMQGLSTANART 232
Query: 716 LAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
L QT LG+A M+ + G+ PA L+ VTSP G+T ++N F++ + A+ AA R
Sbjct: 233 LVQQTLLGAARMMTELGETPAALRHRVTSPHGTTEAAIATFQENDFQALVAKAIDAATRR 292
Query: 893 CKIVKK 910
+ + K
Sbjct: 293 ARALGK 298
>UniRef50_Q1MPA3 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Lawsonia intracellularis PHE/MN1-00|Rep:
Pyrroline-5-carboxylate reductase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 278
Score = 116 bits (279), Expect = 1e-24
Identities = 71/190 (37%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = +2
Query: 338 PALKEIKNLPSAK-NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFS- 511
P LKE LP + + IS+A GIT + + S VIRVMPNTPALV G A
Sbjct: 85 PILKEC--LPFLRPGHIIISLAAGITQIMLTEAVESFCPVIRVMPNTPALVGSGIFALCL 142
Query: 512 RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 691
K + E +Q LF +G +PE Q A TAL G GPAYV+ +++L + V G
Sbjct: 143 EDPKLSNEQSQSVIDLFSLIGLPIILPEKQFSAFTALIGCGPAYVFHFMDALVEAAVTLG 202
Query: 692 LPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 868
PR ++ + ++ GSA + + G+HPA+L++ V SP G T H+++ R II
Sbjct: 203 FPRQQSIYMVSELLNGSAKLATQPGNHPALLREQVCSPGGITIAAINHMDRTAIRGNIID 262
Query: 869 AVSAAVDRCK 898
A+ A + K
Sbjct: 263 AILTAYKKEK 272
>UniRef50_A5FLP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Flavobacterium|Rep: Pyrroline-5-carboxylate reductase -
Flavobacterium johnsoniae UW101
Length = 258
Score = 116 bits (278), Expect = 2e-24
Identities = 81/264 (30%), Positives = 122/264 (46%), Gaps = 1/264 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MK+ IGGG L ++A G A +K +++T + ++A+ + G T +N
Sbjct: 1 MKVHIIGGGNLGVSIALGI--AKFSKNNQVTVTRR--NIAAIQYLTEYGITVSNDNKHNI 56
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L EI LP +NK S G+++ ++S +E V+R+MP
Sbjct: 57 QEADVVILTIKPYQVDTVLAEI--LPVIQNKTIASAVSGLSLDILQSKTNNEYPVVRIMP 114
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N A E A S K E+A LF+ +GT + E MDA T L G AY
Sbjct: 115 NIAAQFGESATCISFPEKYK-ENAAPIVDLFQDLGTAPVIDEKLMDAATVLGACGTAYAL 173
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGT 826
I + G+ G + AL +AAQT G+A M ++ HP L D VT+P G T G
Sbjct: 174 RYIRASMQAGIEIGFDSNTALAIAAQTVKGAAKMLLEERVHPEQLIDRVTTPQGCTIVGL 233
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK 898
+E NGF S++I + ++ + K
Sbjct: 234 NEMEHNGFSSSLIKGIKTSLKQIK 257
>UniRef50_A4XKQ2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Pyrroline-5-carboxylate reductase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 260
Score = 115 bits (277), Expect = 2e-24
Identities = 80/267 (29%), Positives = 124/267 (46%), Gaps = 2/267 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGL-GATALFENXXX 286
MKIG IG G +A ++A + K + C+ D A F L GAT L
Sbjct: 1 MKIGIIGCGNMANSIAYS-----ITKTQKHQLFCYDVDETKADKFSELYGATKLMSENEV 55
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
L++IK++ +K+ +S+A GI++ ++ ++ +++RVM
Sbjct: 56 VLNCDIIIIAVKPKDIFNVLRKIKDVVG--DKIIVSIAAGISVERIK-DVVGNKKIVRVM 112
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PN V+EG E+ ++LFK++G V E MDAITAL GSGPA+V
Sbjct: 113 PNININVEEGILGVCFSESVLQEEKDKVTELFKSMGAVIVVDEKFMDAITALFGSGPAFV 172
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEG 823
+ES D V+ G + + L + G+ +K +KD VTSP G+T EG
Sbjct: 173 AHFVESYIDATVKLGFSKQESYDLVLKLFYGTIVNMKNNMLTTHQIKDMVTSPGGTTIEG 232
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCKIV 904
E+ + AII + A +R K +
Sbjct: 233 LIEFERKALKGAIIDGIIKAYERSKSI 259
>UniRef50_Q9YFV4 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Thermoprotei|Rep: Pyrroline-5-carboxylate reductase -
Aeropyrum pernix
Length = 279
Score = 115 bits (276), Expect = 3e-24
Identities = 81/275 (29%), Positives = 136/275 (49%), Gaps = 2/275 (0%)
Frame = +2
Query: 104 EAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXX 283
+ +++ +G G++ A+ +S G +T + + + + LGA A +N
Sbjct: 8 KGLRVAVLGVGKIGGAIVKSLLSCGAV----VTGTGRRRE--TLERISRLGAEATVDNRL 61
Query: 284 XXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRV 463
L+EI+++ + K+ +SV G+ ++T+ L + V R
Sbjct: 62 AAKVSDVVILSVKPYQLPRLLEEIRDV--MEGKIVVSVVAGVRLSTLSRALEG-SHVYRA 118
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
MPN AL+ A + T + A + +G+ +PE MD TAL GS PAY
Sbjct: 119 MPNINALIGRSTTAVAEYTGD--KRASFVESILSCMGSVYWIPEEWMDVWTALVGSMPAY 176
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA--MVKTGDHPAMLKDNVTSPAGSTA 817
V ++I+SL GGV GLPR++A + A TLG+ A + K HP++L+D VT+PAG+T
Sbjct: 177 VAVMIDSLTLGGVSAGLPREVAFK-AVIDTLGATAEHLGKRDIHPSVLRDEVTTPAGTTI 235
Query: 818 EGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 922
EG +E G +A+I V AA R + + +++
Sbjct: 236 EGLKVIEGEGVDAALIRTVEAAARRAAAIGEAIDN 270
>UniRef50_A6Q4P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Nitratiruptor sp. SB155-2|Rep: Pyrroline-5-carboxylate
reductase - Nitratiruptor sp. (strain SB155-2)
Length = 244
Score = 114 bits (275), Expect = 4e-24
Identities = 68/187 (36%), Positives = 112/187 (59%), Gaps = 1/187 (0%)
Frame = +2
Query: 341 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 520
AL+++ N S K +L IS+ G I+T+ +P++ + +R MPN A +K+ + T
Sbjct: 67 ALEDVANQVSGKAELLISILAGTPISTLHK-IPAQ-KYVRAMPNIAA-IKQASI-----T 118
Query: 521 KATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 697
T + + +L + +G V E ++D TA++GSGPA++ ++ E++ADGGV CGL
Sbjct: 119 AMTGDKDERAIELIEKIGKVVWVESEKELDIATAIAGSGPAFLALVAEAMADGGVLCGLK 178
Query: 698 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 877
RD+A L + AA+ + +HPA++KD V SPAG+TA G LE+NG R+ I ++
Sbjct: 179 RDIAYGLVSGLFQSYAAI--SEEHPALIKDKVMSPAGTTAAGYKALEENGVRNGFIQSIQ 236
Query: 878 AAVDRCK 898
A ++ K
Sbjct: 237 KAFEKTK 243
>UniRef50_P32263 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Saccharomycetales|Rep: Pyrroline-5-carboxylate reductase
- Saccharomyces cerevisiae (Baker's yeast)
Length = 286
Score = 114 bits (275), Expect = 4e-24
Identities = 67/169 (39%), Positives = 93/169 (55%), Gaps = 1/169 (0%)
Frame = +2
Query: 380 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 559
KL IS+A G TI + + V RVM NTPA G A S + E L ++L
Sbjct: 109 KLLISLAAGWTIDQLSQYTST---VCRVMTNTPAKYGYGCAVVSYSADVSKEQKPLVNEL 165
Query: 560 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
VG E+PE MDA TAL GSGPA+V +++ESL + G++ G+P + A + G
Sbjct: 166 ISQVGKYVELPEKNMDAATALVGSGPAFVLLMLESLMESGLKLGIPLQESKECAMKVLEG 225
Query: 740 SAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
+ MV K+G HP++LK V +P G+T G +E+ G +S II V A
Sbjct: 226 TVKMVEKSGAHPSVLKHQVCTPGGTTIAGLCVMEEKGVKSGIINGVEEA 274
>UniRef50_Q8G5S6 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Bifidobacterium|Rep: Pyrroline-5-carboxylate reductase -
Bifidobacterium longum
Length = 266
Score = 114 bits (274), Expect = 5e-24
Identities = 77/259 (29%), Positives = 117/259 (45%), Gaps = 4/259 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
IGFIG G +A A+A G ++AG +I A D K +GA L
Sbjct: 6 IGFIGYGNMAQAIAEGLVAAGAVDGADIVACAAHYDKLE-KTTMKVGAKPLHNAAEVVAA 64
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSE---ARVIRVM 466
+K + + ++K +S+A G + ++ A + +
Sbjct: 65 SDMVVIAIKPYQIESVIKPVIGAIADEDKFVVSIAAGWDLDKYRDLFGADFNAAHIQCTI 124
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PNTP V +G T A++ +LF ++ + V M ++G PA+
Sbjct: 125 PNTPMAVGKGVLVTEADNTLTDTQAEVFERLFSSISLIERVDSAHMGIGMCIAGCAPAFT 184
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEG 823
M IE+L D GV+ GL R A RLAA+ G A+ +K HP ++KD V SP G+T +G
Sbjct: 185 DMYIEALGDAGVKYGLQRATAYRLAAKMVEGVGALYLKNETHPGVMKDAVCSPGGTTIKG 244
Query: 824 TYHLEKNGFRSAIIGAVSA 880
LE++ FR A+I AV A
Sbjct: 245 VTSLEESAFRGAVIKAVDA 263
>UniRef50_Q18YN1 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Desulfitobacterium hafniense|Rep:
Pyrroline-5-carboxylate reductase - Desulfitobacterium
hafniense (strain DCB-2)
Length = 267
Score = 114 bits (274), Expect = 5e-24
Identities = 80/268 (29%), Positives = 127/268 (47%), Gaps = 1/268 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KI FIG G +A A+ G + G + +T + + +A K G+ + E
Sbjct: 3 KISFIGAGNMAEAIIKGLMVTG-SYEIRVTNRSNQAKLAQMKEDYGVIPVSFRE---AVK 58
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
AL +I+ S+ N+L ISVA GI +A +E +LP +IR MPN
Sbjct: 59 DSEIILLAVKPKDVGEALAQIREGISS-NQLLISVAAGIPLALLEKHLP-HCPIIRAMPN 116
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
T + V +G + +F AVG + E Q++ + A+SGSGPAY Y+
Sbjct: 117 TSSAVLHSMTGLVKGQGVNEAKQRDVEDIFGAVGKYIWITEEQINPLIAMSGSGPAYFYL 176
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
E+L GV G +++A LA +T +G+A M+ ++G P L+ VTSP G+T E
Sbjct: 177 FTEALVKAGVDMGFSQEVAENLAKETLMGAAKMLAQSGKSPGELRVAVTSPKGTTQEALE 236
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+ G + A A R + ++++
Sbjct: 237 VFREQGLEELVAQAAKACKHRAQAMERE 264
>UniRef50_A3ERR0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Leptospirillum sp. Group II UBA|Rep:
Pyrroline-5-carboxylate reductase - Leptospirillum sp.
Group II UBA
Length = 288
Score = 114 bits (274), Expect = 5e-24
Identities = 81/261 (31%), Positives = 128/261 (49%), Gaps = 5/261 (1%)
Frame = +2
Query: 125 IGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXXX 304
+GGGR+ A +G + G E C P D + G G + +
Sbjct: 13 LGGGRMGQAFLSGVLKKGRRNRPEKVFVCDP-DPGVRERLSGEGTVEVVPSVDELVRKGE 71
Query: 305 XXXXXXXXXXX-PAL-KEIKNLPSAKN--KLFISVAMGITIATVESNLPSEARVIRVMPN 472
P+L E+ + + + L +SV G ++T++ +LP R IR M N
Sbjct: 72 KSSPSLVFWAVKPSLFSELAPVLRSLDICPLGVSVMAGTPLSTLQESLP-RWRWIRTMSN 130
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYM 652
EG + G +A ED S++F +G +PE D TAL+GSGP + +
Sbjct: 131 LALTRGEGMTLLTPGARAQDEDLSAVSRIFLELGRVMMLPEKDFDVATALAGSGPGLMAL 190
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
++E+L+D GVR GL R+ A+ L+AQ G+A+++ + G P+ L+ V SP+G+T EG
Sbjct: 191 VLEALSDAGVRHGLKREDAVFLSAQMLKGTASLILEEGMDPSELRKRVASPSGTTIEGLV 250
Query: 830 HLEKNGFRSAIIGAVSAAVDR 892
LE+ G R++ I AV+ V R
Sbjct: 251 ALEEGGVRASFIQAVARMVGR 271
>UniRef50_O66553 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Aquifex aeolicus|Rep: Pyrroline-5-carboxylate reductase
- Aquifex aeolicus
Length = 265
Score = 114 bits (274), Expect = 5e-24
Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 1/173 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
+ +S+ G++I +E L + +++RVMPN V G A + + E+ +L
Sbjct: 91 IILSIMAGVSIEKMEKILGKDKKIVRVMPNVNVAVGSGVMAITDNGNLSEEERSKVEELL 150
Query: 563 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
+ GT + E DA TAL+GSGPA+V+ I++LA GV G + ALR+A T +GS
Sbjct: 151 LSCGTLYRIEERLFDAFTALAGSGPAFVFSFIDALALAGVHQGFSYEQALRIALDTVMGS 210
Query: 743 AAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
A ++K +P L VTSP G+T EG +LE+ GF+ ++ ++ + K
Sbjct: 211 AKLLKEFQVNPNELIAKVTSPGGTTIEGIKYLEEKGFKGTVMECINRTSQKAK 263
>UniRef50_Q4TIV0 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Euteleostomi|Rep: Pyrroline-5-carboxylate reductase -
Tetraodon nigroviridis (Green puffer)
Length = 377
Score = 113 bits (272), Expect = 9e-24
Identities = 54/99 (54%), Positives = 69/99 (69%)
Frame = +2
Query: 440 SEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITA 619
S +V+R M NTP +VKEGA ++ GT A ED +L QL +VG C EV E +DA+T
Sbjct: 165 SAPKVMRCMTNTPVVVKEGATVYATGTHAEVEDGKLLEQLMASVGFCTEVEEDLIDAVTG 224
Query: 620 LSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 736
LSGSGPAY + +++LADGGV+ GLPR LA+RL AQ L
Sbjct: 225 LSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALL 263
Score = 51.6 bits (118), Expect = 4e-05
Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M +GFIG G+LA AL GF +AG+ ITAS +D+ + + +G N
Sbjct: 3 MSVGFIGAGQLAHALVKGFTAAGVIAAHRITASSPDTDLPTVSGLRKMGVNLTTSNKETV 62
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNK-LFISVAMGITIATVESNLPS 442
L EI P +++ L +S A G+TI+++E P+
Sbjct: 63 SKSDVLFLAVKPHIIPFVLDEIG--PDIEDRHLIVSCAAGVTISSIEKVCPN 112
>UniRef50_A7BDU0 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 268
Score = 113 bits (272), Expect = 9e-24
Identities = 81/266 (30%), Positives = 131/266 (49%), Gaps = 7/266 (2%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M+IGFIG G +A A+A G +++G+ P + S + A A + LGATA N
Sbjct: 1 MRIGFIGTGAMAQAIARGAVASGV-DPATLVFSNRTATKACDLADE-LGATAASSNASLA 58
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKL-FISVAMGITIATVESNLPSEARVIRVM 466
+KEI + + +S+A G T+ + ++ + ++RVM
Sbjct: 59 RQADIVILAVKPKDQRAVIKEISPIVVGHPDVCVVSLAAGRTLDQITTDFGAGIPLVRVM 118
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLF--KAVGTCDEVPEYQMDAITALSGSGPA 640
PN A V + A T A A DAQ+ + F ++G + E AL+ PA
Sbjct: 119 PNVAATVGQSMTAL---TAARATDAQVAAVRFLMDSIGRTILIDEDYFPVFQALASCSPA 175
Query: 641 YVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV----KTGDHPAMLKDNVTSPAG 808
+ + +++S A G++ GL +D A+ +AAQ G+AA++ + G PA L D VTSP G
Sbjct: 176 WYFQIVDSFARAGLKHGLSKDSAVEIAAQAMAGAAALLLAERENGTIPAQLIDRVTSPGG 235
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAV 886
+T G E+ G +A++ AV A++
Sbjct: 236 TTIAGLLAAEEGGLSTALVSAVDASI 261
>UniRef50_Q12641 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Neurospora crassa|Rep: Pyrroline-5-carboxylate reductase
- Neurospora crassa
Length = 311
Score = 113 bits (272), Expect = 9e-24
Identities = 63/177 (35%), Positives = 100/177 (56%), Gaps = 9/177 (5%)
Frame = +2
Query: 380 KLFISVAMGITIATVESNLPSEAR--------VIRVMPNTPALVKEGAAAFSRGTKATAE 535
K+ IS+ G+T+ +E L + V+R MPNT + ++E + +
Sbjct: 115 KIIISICAGVTVPDLERVLREDVGLSADNLPIVVRAMPNTASKIRESMTVINTVDPPLPD 174
Query: 536 DA-QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLAL 712
+L + +F+ +G +P + MDA T+L SG A+ +++E+ ADGGV GLPR A
Sbjct: 175 TVTELLTWIFERIGEVVYLPPHLMDACTSLCASGTAFFALMMEAAADGGVAMGLPRAEAN 234
Query: 713 RLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
R+AAQT G+A +V G+HPA+L++ V++P G T G LE+ G R+A+ AV A
Sbjct: 235 RMAAQTMRGAAGLVLEGEHPAILREKVSTPGGCTIGGLLVLEEGGVRAAVARAVREA 291
>UniRef50_Q21EI2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Saccharophagus degradans 2-40|Rep:
Pyrroline-5-carboxylate reductase - Saccharophagus
degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Length = 285
Score = 112 bits (270), Expect = 2e-23
Identities = 81/281 (28%), Positives = 128/281 (45%), Gaps = 8/281 (2%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
L+ KI FIG G +A A+ G + G+A P I C PS+ A+ G +N
Sbjct: 6 LVNDAKIAFIGAGNMAAAIIAGLVKQGVA-PANIEV-CAPSEGNRARLASEYGVVHSADN 63
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEAR-- 451
++ + N + +SVA GIT ++ + L + A+
Sbjct: 64 NAAAAKADILVLAVKPQMMREVCAQLAEHRNP-NCVVLSVAAGITCQSLANWLATPAQPA 122
Query: 452 ----VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAIT 616
V+R MPNTP+ + GA + + AVG V E +++ +T
Sbjct: 123 ENIAVVRTMPNTPSHIGLGACGLFASSAVAQTQKDQAQAIMAAVGLAVWVNSEDEINIVT 182
Query: 617 ALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAM-LKDNV 793
A+SGSGPAY +++ E++ D + GL R A +L QT LG+A + +T + A+ L+ V
Sbjct: 183 AVSGSGPAYFFLVFEAMIDAAEKMGLDRQTATQLTLQTALGAAKLAQTSEDDAVTLRKKV 242
Query: 794 TSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
TSP G+T E+N R A+ A DR + + +L
Sbjct: 243 TSPNGTTERAIASFEQNKLRDTFAAAMQACSDRAQQLATEL 283
>UniRef50_A0NYJ6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Stappia aggregata IAM 12614|Rep: Pyrroline-5-carboxylate
reductase - Stappia aggregata IAM 12614
Length = 272
Score = 112 bits (270), Expect = 2e-23
Identities = 65/179 (36%), Positives = 103/179 (57%), Gaps = 3/179 (1%)
Frame = +2
Query: 371 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 550
A + L +SVA G ++ E + R MPNTPA+VK G A +A+
Sbjct: 91 ASDTLVLSVAAGTPVSKFEEFF-GHVPICRCMPNTPAMVKRGITAVYPTPAVSAQAKDDV 149
Query: 551 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 727
++L +VG + E Q+D +T +SGSGPAYV+ L E+L++ G + GLP ++A LA
Sbjct: 150 TRLLSSVGKVVWLDSEDQIDLVTGVSGSGPAYVFFLAEALSEAGRQAGLPEEIAQELAIA 209
Query: 728 TTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEG-TYHLEKNGFRSAIIGAVSAAVDRCK 898
T G+ ++ ++G+HP++L+ NVTSP G+TA + +G + + AV+AAV R +
Sbjct: 210 TVCGAGELMHQSGEHPSVLRKNVTSPNGTTAAALDVLMHADGLQPVMTEAVAAAVKRAR 268
>UniRef50_Q0U2X1 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 307
Score = 112 bits (270), Expect = 2e-23
Identities = 63/169 (37%), Positives = 93/169 (55%), Gaps = 9/169 (5%)
Frame = +2
Query: 374 KNKLFISVAMGITIATVE--------SNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT 529
K K+ +S+ G+T +E S + RV+RVMPNT + V E + T
Sbjct: 120 KGKVLVSILAGVTQQQIEDFLYPEGASKVDGACRVVRVMPNTASFVGESMSVIQTSTPPL 179
Query: 530 AEDAQ-LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 706
+E L + +F ++G +P QMD TAL GSGPA+ +++E+ ADG V GLPR
Sbjct: 180 SESQHNLVNFVFSSIGRVVSLPPAQMDISTALCGSGPAFFALILEAAADGAVAMGLPRAE 239
Query: 707 ALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFR 853
A +AAQT G+ +V G+HPA+LKD V++P G H+ + G+R
Sbjct: 240 AQLMAAQTMRGTTGLVLNGEHPAVLKDKVSTPRG-VHHRRAHVARGGWR 287
>UniRef50_A6SCY1 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 301
Score = 112 bits (270), Expect = 2e-23
Identities = 60/174 (34%), Positives = 94/174 (54%), Gaps = 7/174 (4%)
Frame = +2
Query: 374 KNKLFISVAMGITIATVESNLPS-------EARVIRVMPNTPALVKEGAAAFSRGTKATA 532
++K+ +S+ G+TI +ES L S A + R MPNT + V+E +A
Sbjct: 112 QDKVLVSLLAGVTIPDIESVLQSVGGKSYYPATIARAMPNTASFVRESITVIETPEATSA 171
Query: 533 EDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLAL 712
+ LF+++G + D TAL S PA+ +++++L DG V GL R A
Sbjct: 172 SHLLAINWLFESIGKIKHISATNFDTCTALGASTPAFFAIILDALIDGAVTLGLTRKDAT 231
Query: 713 RLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 874
+AAQ+ G AA+V G+HPA +K+N+T+P GST G LE+ R+ + GA+
Sbjct: 232 LMAAQSMKGCAALVLAGEHPASVKENITTPGGSTIMGVLALEQGNVRAVVAGAL 285
>UniRef50_Q5QY55 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Idiomarina|Rep: Pyrroline-5-carboxylate reductase -
Idiomarina loihiensis
Length = 274
Score = 111 bits (268), Expect = 3e-23
Identities = 79/262 (30%), Positives = 116/262 (44%), Gaps = 3/262 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I FIG G + ++ G +G D++ S +PSD K LG +N
Sbjct: 7 IAFIGAGNMTQSIVGGMCKSGYPA-DKVWVS-NPSDAKLEKMKSELGVNTSNDNLEVVNN 64
Query: 296 XXXXXXXXXXXXXXPALKEIK-NLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
++ N+ + +KL I++A GI I L R+IRVMPN
Sbjct: 65 ADAIVLSVKPQLMAEVCAHLRENVHNLTDKLIITIAAGIRIPKYREYLGENIRIIRVMPN 124
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVY 649
TP+LV +G + D ++ F VG T E Q+D + A++GSGPAY +
Sbjct: 125 TPSLVGQGMSGLVTDDSVDEADKNFVTEAFNGVGETLWVSDEDQLDILGAVAGSGPAYFF 184
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAM-LKDNVTSPAGSTAEGT 826
++SLA G + A + QT LG+A M K + L+ VTS GSTA+G
Sbjct: 185 EFMDSLAKAATELGFDAEKARAMVQQTCLGAAQMAKESELSLEDLRKQVTSKGGSTAKGV 244
Query: 827 YHLEKNGFRSAIIGAVSAAVDR 892
+ + AV AAV+R
Sbjct: 245 EAYQDSDLHGISEKAVKAAVNR 266
>UniRef50_A4BKC4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Reinekea sp. MED297|Rep: Pyrroline-5-carboxylate
reductase - Reinekea sp. MED297
Length = 273
Score = 111 bits (268), Expect = 3e-23
Identities = 73/271 (26%), Positives = 118/271 (43%), Gaps = 2/271 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
+GFIG G ++ A+ G ++AG A D + + A+ +Q LG +
Sbjct: 5 LGFIGAGNMSGAIIKGLLNAGTAPGDLLICA---RTQATLDTYQALGCATTLDASEVMRT 61
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
L+ + + A L +SV I ++E L +IR MPNT
Sbjct: 62 CDAVMLGVKPQMLKDVLQPLADEAQAHQPLLLSVVAAIPATSIERWLGGNLAIIRTMPNT 121
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYM 652
P+LVK+GA + T L F +G V E + A+TA +GS PAY +
Sbjct: 122 PSLVKQGATGLYANERVTDAQKSLAETTFAGIGRYSWVDNEADLHAVTATAGSAPAYFFQ 181
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTY 829
ES+ + GL + L QT LG+A M+ +T A ++ NV SP G+T
Sbjct: 182 FAESMQKTALELGLTDAQSRTLIGQTMLGAATMILETDTDIAQMRKNVCSPNGTTERAIQ 241
Query: 830 HLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 922
+ + + + A+ A ++R + + +L D
Sbjct: 242 SFQTDDIDAVVRRAMLACLERSEELSSELGD 272
>UniRef50_Q6LML8 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Photobacterium profundum (Photobacterium sp.
(strain SS9))
Length = 272
Score = 111 bits (267), Expect = 4e-23
Identities = 74/273 (27%), Positives = 130/273 (47%), Gaps = 3/273 (1%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENX 280
+E I FIG G +A ++ G +++G ++ITA+ PS+ + G +N
Sbjct: 1 MEQRSITFIGAGNMARSIIAGLVASGYPA-NKITATA-PSEARREPLARDYGIHTDADNL 58
Query: 281 XXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIR 460
++++ + NKL IS+A GI+ + + L +E ++R
Sbjct: 59 RAAQQADVIVLAVKPQLMESVCSALQDIDFS-NKLVISIAAGISASRLNEMLNTELNLVR 117
Query: 461 VMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGP 637
VMPNTP+L+ +G + + D QL +AVG C E ++ + A +GS P
Sbjct: 118 VMPNTPSLIGKGMSGLFASQSVSENDKVYAEQLMQAVGEACWVQQESGINGVIAAAGSAP 177
Query: 638 AYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAM--LKDNVTSPAGS 811
AY ++ +E++ ++ G D A L Q+ LG+A +VK + L++ VTS G+
Sbjct: 178 AYFFLFMEAMQKEAIKQGFDADTARLLVQQSALGAAELVKANPETELSTLREQVTSKGGT 237
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
TAE ++ + A+ AAV R + ++K
Sbjct: 238 TAEAIRTFNEHQLSDIVAKAMRAAVSRAEEMEK 270
>UniRef50_Q5WH55 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus clausii KSM-K16|Rep: Pyrroline-5-carboxylate
reductase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 111 bits (267), Expect = 4e-23
Identities = 67/179 (37%), Positives = 93/179 (51%), Gaps = 1/179 (0%)
Frame = +2
Query: 359 NLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED 538
+L + +L ISVA GI + T+ES LP++ VIR MPNT A V A S GT AT
Sbjct: 88 SLLDPQKQLVISVAAGIKLETLESWLPADTAVIRAMPNTSARVLASATTLSIGTYATEWQ 147
Query: 539 AQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRL 718
LF ++GT V E QMDA T ++GSGPAY+Y + E++ + + GL A L
Sbjct: 148 LAFAKTLFSSIGTVTVVDEQQMDAATGIAGSGPAYIYYVAEAMLNAAIAEGLSPAEARAL 207
Query: 719 AAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
QT G+A + + P L + SP G+T HL+ + + A+ AV R
Sbjct: 208 INQTIGGAAKQLSNSSKSPKDLYKEIMSPNGTTEAAIAHLDHSSAQELFQQAIHQAVKR 266
>UniRef50_Q04FB4 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Oenococcus oeni|Rep: Pyrroline-5-carboxylate reductase -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 261
Score = 111 bits (267), Expect = 4e-23
Identities = 73/261 (27%), Positives = 126/261 (48%), Gaps = 1/261 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MK GF+G G L+ A+ G + AG D +S H + + S + A +
Sbjct: 1 MKYGFLGAGNLSSAIIMGLLKAGFRSEDIFVSSPHSAALLSKRL-----AINNVDEDRLL 55
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
++++ + A NKL +SV ++ + LP+ A+++RV+P
Sbjct: 56 ADCDLIVLAFLPEQLGSIVQQVGSEKFA-NKLIVSVLGSTSLKELTEFLPT-AKIVRVLP 113
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N A + + G + ED +LT +A GT E+ E A +A++GSGPA+V
Sbjct: 114 NVNAEFNNSLTSVAFGQNLSNEDLKLTKNFLQAFGTIIELAERDFPAFSAIAGSGPAFVA 173
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAA-MVKTGDHPAMLKDNVTSPAGSTAEGT 826
+ I++L + G++ G+ +L++A T GS ++++G L V SP GSTA+G
Sbjct: 174 LFIKALQEAGIKQGIDSKESLQIALHTIKGSTENILQSGKTADQLVKKVASPGGSTADGV 233
Query: 827 YHLEKNGFRSAIIGAVSAAVD 889
LE+N F + A+ A ++
Sbjct: 234 ESLEENHFIETVNNAILATIN 254
>UniRef50_A4SZT4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Polynucleobacter sp. QLW-P1DMWA-1|Rep:
Pyrroline-5-carboxylate reductase - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 289
Score = 111 bits (267), Expect = 4e-23
Identities = 84/275 (30%), Positives = 127/275 (46%), Gaps = 8/275 (2%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVA----SAKAFQGLGAT--ALFEN 277
I FIGGG + AL +G I+ G +P++I+ + A QG+GA F+
Sbjct: 15 ITFIGGGNMGRALISGLIANGF-EPNQISVVESNASTALKLHEDYGVQGIGALDHIAFDF 73
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
++K+ SA L +S+A GI + + L R +
Sbjct: 74 SKNNVVVMAIKPQDFNVVAKGLASKLKHA-SAPGPLILSIAAGIRLKDMSRWL-DHTRCV 131
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQ-MDAITALSGSG 634
R MPNTPAL+ +G D L + AVG V E MDA+TA+SGSG
Sbjct: 132 RAMPNTPALIGKGITGLFADAAVGQSDRTLAETICNAVGQSVWVSEENLMDAVTAVSGSG 191
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGS 811
PAYV+ IE++ G + GL A +LA T G+ + D H +L++ VTS G+
Sbjct: 192 PAYVFAFIEAMQSAGEKLGLDEKTARKLAYATLEGATQLAHNSDEHAGVLRERVTSKGGT 251
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
TA ++++G+ + A+ AA R K + +L
Sbjct: 252 TAAALDVMKQHGWNEILEKAIDAASQRGKTMGDEL 286
>UniRef50_A0Z2R8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
marine gamma proteobacterium HTCC2080|Rep:
Pyrroline-5-carboxylate reductase - marine gamma
proteobacterium HTCC2080
Length = 275
Score = 111 bits (267), Expect = 4e-23
Identities = 79/269 (29%), Positives = 122/269 (45%), Gaps = 3/269 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
IGF+G G +A A+ G +SAG + PS+ A K LG + +
Sbjct: 8 IGFVGAGNMASAIIGGLLSAGYDSAR--LCAIDPSEAAQTK-LHNLGISEVGGQPGPTFR 64
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLP-SEARVIRVMPN 472
A E A + +SVA GI+++ ++ L S A V+R MPN
Sbjct: 65 TSELVIVAVKPQFMQAATEGIKKHLAPETVVMSVAAGISVSALKDQLSNSNAPVVRCMPN 124
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVY 649
TPALV GA+ + T + VGT + E +D +TA+SGSGPAY +
Sbjct: 125 TPALVGAGASGLFASPEVTDRQRAGIDAVMGVVGTTVWLEKESHIDVVTAISGSGPAYFF 184
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGT 826
+E++ G R GL + A +L QT LG+A + P L+ NVTSP G+T
Sbjct: 185 AFMEAMIATGERMGLDHETASQLTLQTALGAAKLATQQSDPVNELRRNVTSPGGTTERAL 244
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+++ + + + A + R + + K+
Sbjct: 245 ESFDQDNLEALVNRGMQACLARAQEMAKE 273
>UniRef50_UPI000038E2C3 Cluster: hypothetical protein Faci_03001369;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03001369 - Ferroplasma acidarmanus fer1
Length = 261
Score = 111 bits (266), Expect = 5e-23
Identities = 64/194 (32%), Positives = 108/194 (55%), Gaps = 1/194 (0%)
Frame = +2
Query: 344 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 523
++EI++ +AK KL IS GIT++ ++ L ++ V R MP+ P LV++ A+S
Sbjct: 72 MEEIRS--AAKGKLVISFMAGITLSHMQEML-KDSMVARGMPSIPMLVQKSVTAYSY-KN 127
Query: 524 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 703
E + ++ K G+ + E MDA+T LSGSGPA+V ++ +S+ + G+ G+P+
Sbjct: 128 LDKEHKDVLEKVLKGFGSAVHIDESYMDAVTGLSGSGPAFVAIMADSMINAGILAGIPKI 187
Query: 704 LALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 880
A L T + + ++++ G + L+D V +P G+T G Y +EK R+AI AV
Sbjct: 188 QARELVIDTFINTMSLMREKGFSASDLRDEVMTPGGTTVAGIYEMEKANARTAIANAVLG 247
Query: 881 AVDRCKIVKKQLND 922
+ R K + K D
Sbjct: 248 SYRRAKEISKNSRD 261
>UniRef50_Q2UTF9 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Pezizomycotina|Rep: Pyrroline-5-carboxylate reductase -
Aspergillus oryzae
Length = 299
Score = 111 bits (266), Expect = 5e-23
Identities = 69/195 (35%), Positives = 103/195 (52%), Gaps = 13/195 (6%)
Frame = +2
Query: 377 NKLFISVAMGITIATVE----------SNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 526
NKL ISVA G T +E SN A V+R +PN A V +G A
Sbjct: 102 NKLLISVAAGWTRQKLETTLYGSPTTTSNAEGRAWVVRTLPNIAASVSQGLTAIEISEPE 161
Query: 527 TAEDAQ-LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 703
E Q +T +F +G +P MDA TA++GS PA+ ++++++ D V G+PRD
Sbjct: 162 VPEHYQKITDAVFDNLGKTVHIPPTLMDATTAVAGSTPAFFAVIVDAMIDAAVAVGVPRD 221
Query: 704 LALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
LA + Q G+AA++++G HPA+L+D TSP G T G +E+ G R + A+ A
Sbjct: 222 LARTMTVQAMTGTAALLQSGMHPAVLRDQGTSPEGCTIGGLMVMEEAGVRGHVGRALREA 281
Query: 884 VDRCKIV--KKQLND 922
V +++ + LND
Sbjct: 282 VTIARLMDGTRHLND 296
>UniRef50_Q087E8 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Shewanella|Rep: Pyrroline-5-carboxylate reductase -
Shewanella frigidimarina (strain NCIMB 400)
Length = 292
Score = 110 bits (265), Expect = 6e-23
Identities = 72/264 (27%), Positives = 112/264 (42%), Gaps = 3/264 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I FIGGG +A A+ +G + G + + C PS +N
Sbjct: 26 IAFIGGGNMARAIISGLLKQGHNSANILV--CAPSQTTRHDLIDKFNVKVHQDNTAAVAF 83
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKN-KLFISVAMGITIATVESNLPSEARVIRVMPN 472
+++ + N KL IS+A G+ AT+ L +VI MPN
Sbjct: 84 ADVIIVAVKPFVVPVVCEQLSEVMQYDNRKLVISIAAGVKHATLRQKLHFSPKVICAMPN 143
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVY 649
P + EG G A D L +L +AVG T E QM I A +GS PAY++
Sbjct: 144 LPTAIGEGLTGLYAGPDTHANDIALAERLMRAVGETVWLKEESQMSTIVAAAGSSPAYLF 203
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHP-AMLKDNVTSPAGSTAEGT 826
+ +E++ + GLP ++A + Q+ +G+ +M H A L+ VTSP G+T +
Sbjct: 204 LFLEAMEKAAIEQGLPPEIAAKAVLQSAMGAISMAMNSQHNLASLRHQVTSPKGTTEQAI 263
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK 898
+ + A++ A R K
Sbjct: 264 LAFQDGDLDDLVASAMACATTRAK 287
>UniRef50_Q3ZWQ2 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Dehalococcoides|Rep: Pyrroline-5-carboxylate reductase -
Dehalococcoides sp. (strain CBDB1)
Length = 267
Score = 110 bits (264), Expect = 8e-23
Identities = 81/264 (30%), Positives = 119/264 (45%), Gaps = 3/264 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVAS-AKAFQGLGATALFENXXX 286
M I FIGGG + A+ I + P IT S ++ + + G+ TA N
Sbjct: 1 MNIAFIGGGNMGEAILGALIQKNICPPQNITVSEIKAERRTYLETSYGIKTTA--SNPDA 58
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
E+K A +L IS+ G T++ + L +A V+RVM
Sbjct: 59 IKSAEVVLLAIKPQNLPELSAELKG-KLADKQLVISIIAGATLSKLSGGLAHKA-VVRVM 116
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGT-CDEVPEYQMDAITALSGSGPAY 643
PNTPA++ G + ++ + + A+G E +DA TA+SGSGPAY
Sbjct: 117 PNTPAMIGMGMSVWTALPSVSPAQKDQAKAILSAMGKEIYTGKETMLDAATAISGSGPAY 176
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAE 820
++ +E L + G + A L +QT GSA K+G L+ NVTSP G+TAE
Sbjct: 177 FFLFMEGLEKAALEMGFTPEEASILVSQTAAGSAIYAGKSGLALTQLRKNVTSPGGTTAE 236
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDR 892
E+ G + II A AA +R
Sbjct: 237 AIKAFEEAGLEATIIKAAKAAFNR 260
>UniRef50_Q2S8M4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Hahella chejuensis KCTC 2396|Rep:
Pyrroline-5-carboxylate reductase - Hahella chejuensis
(strain KCTC 2396)
Length = 276
Score = 110 bits (264), Expect = 8e-23
Identities = 72/265 (27%), Positives = 120/265 (45%), Gaps = 2/265 (0%)
Frame = +2
Query: 104 EAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXX 283
E ++ FIG G +A A+ G I+ G P A+ P++ +A G +N
Sbjct: 3 EHPQLTFIGAGNMARAILGGLIANGY--PANRLAATAPAEQELKEAADAFGIPTSTDNQT 60
Query: 284 XXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRV 463
+ + + + L +S+A G++ +E+ L + V+R
Sbjct: 61 FMADCDALILCVKPQVMQAVCEGLADAVQQRRPLIVSIAAGVSCEQIEAWLGGDLPVVRC 120
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQ-MDAITALSGSGPA 640
MPNTPA V GA+ + + ++ LF AVG + + + +TALSGSGPA
Sbjct: 121 MPNTPAQVHLGASGLYANPRVSEAQREIADNLFSAVGIVAWTSKQEDIHTVTALSGSGPA 180
Query: 641 YVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTA 817
Y +M +E++ + GL A LA QT G+A + ++ + PA LK V SP G+T
Sbjct: 181 YCFMFMEAMEEAAASLGLNPASARTLAIQTMRGAAELATRSEESPAQLKKRVMSPGGTTE 240
Query: 818 EGTYHLEKNGFRSAIIGAVSAAVDR 892
+ E+ ++ + A+ A R
Sbjct: 241 QAIKSFEEQDMKAMVKTAIRKAWGR 265
>UniRef50_Q974L3 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sulfolobus tokodaii|Rep: Pyrroline-5-carboxylate
reductase - Sulfolobus tokodaii
Length = 259
Score = 109 bits (263), Expect = 1e-22
Identities = 79/272 (29%), Positives = 132/272 (48%), Gaps = 2/272 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M++ IG G++ +A+ G S + EI + + +G+ AT +N
Sbjct: 1 MRVSIIGVGKIGYAILKGLKSLNV----EIIGTGRSEETLDKIKKEGVEATR--DNEYAI 54
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L ++ + + K +SV GI I+T+ + L + A+V R MP
Sbjct: 55 KKSDIIILAVKPQHFHSILDKVSKT-AWEGKKVVSVMAGIRISTL-TRL-TNAKVYRAMP 111
Query: 470 NTPALVKEGAAAFSRGTKATAEDA-QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
N A++ + T A AE+ + ++F+ +G +PE DA TA+ GSGPA+V
Sbjct: 112 NINAVI-------GKATTALAEERDEEVERIFRTIGNVYWIPEELFDAWTAIIGSGPAFV 164
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEG 823
+I++ A G V CG+ R+LA + G+ + K HP +L+D VT+PAG+T G
Sbjct: 165 AEIIDAFALGAVACGMSRELAYQAILDMVEGTVYTLRKDKTHPVLLRDQVTTPAGTTIRG 224
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLN 919
+E G +SAII + AA R + K+++
Sbjct: 225 LMVMESEGIKSAIIKTIEAAYQRSMAIGKEID 256
>UniRef50_Q9WZ47 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Thermotoga|Rep: Pyrroline-5-carboxylate reductase -
Thermotoga maritima
Length = 255
Score = 109 bits (261), Expect = 2e-22
Identities = 56/171 (32%), Positives = 97/171 (56%), Gaps = 1/171 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
+ +S+ G+ I + +V R+MPN V EG A + + E+ +L L
Sbjct: 80 ILLSIVAGLKIEEIRKY--GIHKVARIMPNVAVRVGEGVLATAFSADMSLEERELVKSLL 137
Query: 563 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
+ +G E+ E A+TAL+GSGPA++++++E+ D ++ G+P D A L + GS
Sbjct: 138 EKLGFVVEIEEKLFSAVTALTGSGPAFIFVVVEAFLDAALKMGIPLDTAKELVYRLFKGS 197
Query: 743 AAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
A ++ +TG+HPA+ K V+SPAG+T EG +E+ RS +I ++ ++ R
Sbjct: 198 AELLTETGEHPALWKHRVSSPAGTTIEGLITMERFAVRSGVIESLISSYRR 248
>UniRef50_Q7VYN6 Cluster: Pyrroline-5-carboxylate reductase; n=45;
Proteobacteria|Rep: Pyrroline-5-carboxylate reductase -
Bordetella pertussis
Length = 277
Score = 108 bits (259), Expect = 3e-22
Identities = 89/271 (32%), Positives = 127/271 (46%), Gaps = 8/271 (2%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVA--SAKAFQGLGATALFENXX 283
+ I FIGGG +A ALA+G AG P A+ H D+ S ++ G +A
Sbjct: 5 LSIAFIGGGNMAAALASGL--AGKVCP---AANIHVVDINADSHAGWRARGMSAAAAPDA 59
Query: 284 XXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNL--PSEA--R 451
A+ + + L +SVA GI T+ L P + R
Sbjct: 60 TLAGCRVWVYAVKPQHMREAVAGTRPW-LRPDTLIVSVAAGIRADTLAGWLGEPGQPWQR 118
Query: 452 VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSG 628
++R MPNTPALV G + T +D +L QL +VG V + +DA+TALSG
Sbjct: 119 LVRCMPNTPALVGAGMTGLAALPGVTPQDRELAGQLLTSVGEVVWVDGDAGLDAVTALSG 178
Query: 629 SGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPA 805
SGPAYV++ IE+L GG GL + A +LA T G+ + D PA+L++ VTS
Sbjct: 179 SGPAYVFLFIEALIAGGRAVGLTDEQARQLALGTLAGATRLAAQSDEPPAVLRERVTSKG 238
Query: 806 GSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
G+TA + F + A+ AA R +
Sbjct: 239 GTTAAALDVYAQGDFAGLVERAMQAAARRSR 269
>UniRef50_Q7M801 Cluster: PUTATIVE PYRROLINE-5-CARBOXYLATE
REDUCTASE; n=1; Wolinella succinogenes|Rep: PUTATIVE
PYRROLINE-5-CARBOXYLATE REDUCTASE - Wolinella
succinogenes
Length = 253
Score = 107 bits (258), Expect = 4e-22
Identities = 86/258 (33%), Positives = 127/258 (49%), Gaps = 1/258 (0%)
Frame = +2
Query: 128 GGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXXXX 307
G G++A A+A G +S P EIT +P + A GL A+ LF +
Sbjct: 9 GYGKMALAIAKG-LSGRF--PLEITGR-NPQKIEELIALHGLNASPLFPHDSPLDITDRH 64
Query: 308 XXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALV 487
AL E+ AK S+ G++I + +P+++ IR MPN A +
Sbjct: 65 LLLCVKPY---ALSELSFSGEAKG--VYSILAGVSIERLREKIPAQS-YIRAMPNMAASL 118
Query: 488 KEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIES 664
A A L S++F +GT + E ++DA TAL+GSGPAY+ ++ E+
Sbjct: 119 GSSCTALCGDESLKA----LASEIFAPLGTSLWLDKESKIDAATALAGSGPAYLALMAEA 174
Query: 665 LADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKN 844
L D GVR GL R+ + L G A +++ HPA++K+ VTSP G+TAE LE
Sbjct: 175 LMDAGVREGLSREESKALTQGLFSGFADLLE-DRHPALIKEEVTSPGGTTAEALALLESK 233
Query: 845 GFRSAIIGAVSAAVDRCK 898
G R +I AV AA+ + K
Sbjct: 234 GLRGILIEAVRAALLKAK 251
>UniRef50_Q6MC43 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Pyrroline-5-carboxylate reductase - Protochlamydia
amoebophila (strain UWE25)
Length = 264
Score = 107 bits (258), Expect = 4e-22
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 1/183 (0%)
Frame = +2
Query: 377 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 556
++ +S+ GI T++ S++ V+R+MPN + +G + T +
Sbjct: 83 HQTIVSILAGINYKTLKHRF-SQSIVVRMMPNLALIHGKGVIGLVENDQLTDKLKMQLKA 141
Query: 557 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 736
LF +G+ +PE ++DA+TAL+GSGPA+++ L+ES+ + G+ G A L Q
Sbjct: 142 LFDPLGSVYWLPESKIDALTALTGSGPAFIFALVESMIEAGIYMGFQMTDAKSLIFQMLK 201
Query: 737 GSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
GS A+++T D HPA LK +TSPAG T EG E G RS II A+ ++ K V
Sbjct: 202 GSLALLETTDKHPADLKWQITSPAGMTIEGLKTFEDYGVRSGIIHTFLASFNKIKQVSDS 261
Query: 914 LND 922
L +
Sbjct: 262 LKN 264
>UniRef50_Q5XE84 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Streptococcus|Rep: Pyrroline-5-carboxylate reductase -
Streptococcus pyogenes serotype M6
Length = 256
Score = 107 bits (258), Expect = 4e-22
Identities = 59/188 (31%), Positives = 97/188 (51%), Gaps = 1/188 (0%)
Frame = +2
Query: 338 PALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRG 517
P L E P + IS+A GI++ + + + + ++R+MPN A + + + A +
Sbjct: 67 PQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPMLRIMPNMNAQILQSSTALTGN 126
Query: 518 TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 697
+ E L + G+ ++ E D TAL+GS PAY+Y+ IE+LA GV+ G+P
Sbjct: 127 ALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGMP 186
Query: 698 RDLALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 874
+ AL + QT L SA+ +KT P D + SP G+T G LE+ G + + A+
Sbjct: 187 KAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTTTVSSAI 246
Query: 875 SAAVDRCK 898
+D+ K
Sbjct: 247 DKTIDKAK 254
>UniRef50_Q1PLB2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=8; Prochlorococcus marinus|Rep: Delta
1-pyrroline-5-carboxylate reductase - uncultured
Prochlorococcus marinus clone ASNC1092
Length = 270
Score = 106 bits (254), Expect = 1e-21
Identities = 57/176 (32%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = +2
Query: 374 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 553
K+ L +S+ G++I + P+ + +RV+ N P + +G G + T + Q T
Sbjct: 93 KDNLIVSILAGVSINRLSKKFPNH-KCVRVVTNIPITIGKGLTGICWGEEITEDQKQFTK 151
Query: 554 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 733
+LF+ E PE +D AL+ SGPA + ++IE+L+DGG+ GLP+ ++ L +
Sbjct: 152 KLFENTSKIYEFPEDYLDIFLALTSSGPAIIALIIEALSDGGLSGGLPKIISEELVMEMI 211
Query: 734 LGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
LG+ ++K + LK+ VTSP G+T LEK RSA++ ++ +A +R K
Sbjct: 212 LGTICLLKENKLTTSELKNLVTSPGGTTISALRILEKKSVRSALMESIVSASNRSK 267
>UniRef50_Q5NMY3 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Zymomonas mobilis|Rep: Pyrroline-5-carboxylate reductase
- Zymomonas mobilis
Length = 284
Score = 105 bits (252), Expect = 2e-21
Identities = 59/153 (38%), Positives = 82/153 (53%), Gaps = 1/153 (0%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
IS+ G+ + T+ P ++R MPN P + +G A K T E + +L
Sbjct: 102 ISILAGVELETLRHFFPKAKSIVRAMPNLPVALGKGVVALC-ADKLTDEQRKCIEKLAST 160
Query: 569 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 748
+G + V E Q D TAL+G GPA+VY I++LA G + GL D AL +A T G+A+
Sbjct: 161 LGIFEWVNENQFDTATALAGCGPAFVYRFIDALAQAGQKLGLTADQALPMAIATVEGAAS 220
Query: 749 MVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKN 844
M K D PA L D V SP GST +G L+K+
Sbjct: 221 MAKQADITPAELADKVASPGGSTRKGMDVLDKD 253
>UniRef50_Q9KEG5 Cluster: Pyrroline-5-carboxylate reductase; n=11;
Bacillus|Rep: Pyrroline-5-carboxylate reductase -
Bacillus halodurans
Length = 267
Score = 104 bits (250), Expect = 4e-21
Identities = 64/190 (33%), Positives = 97/190 (51%), Gaps = 3/190 (1%)
Frame = +2
Query: 338 PALKE--IKNL-PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAF 508
PA E +K L P +L I+VA GI +E++LP +MPNT A V E + +
Sbjct: 74 PAAHENVLKKLSPICNGQLVITVAAGIGPTDLETHLPKGTPTAWIMPNTAASVGESMSIY 133
Query: 509 SRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRC 688
G D QL S + A+G +++ E Q+ +TA++GS PA++Y L E+L
Sbjct: 134 CFGQHVKERDKQLISFILDAIGMSEQLTESQIHHLTAITGSAPAFLYFLAEALEQSAQSY 193
Query: 689 GLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 868
G+ + A L GSA M++ P L++ VT+P G+TA G L + F+ A+
Sbjct: 194 GVAPEKARELVIGMITGSAKMLEEYKDPTQLREQVTTPGGATAAGLQSLLHDDFQGALQR 253
Query: 869 AVSAAVDRCK 898
AV A R +
Sbjct: 254 AVQATNGRAQ 263
>UniRef50_A2QNB5 Cluster: Catalytic activity: L-proline + NAD(P)(+)
<=> 1-pyrroline-5- carboxylate + NAD(P)H; n=1;
Aspergillus niger|Rep: Catalytic activity: L-proline +
NAD(P)(+) <=> 1-pyrroline-5- carboxylate + NAD(P)H -
Aspergillus niger
Length = 304
Score = 104 bits (250), Expect = 4e-21
Identities = 65/187 (34%), Positives = 96/187 (51%), Gaps = 13/187 (6%)
Frame = +2
Query: 365 PSAKNKLFISVAMGITIATVESNL--PSEA--RVIRVMPNTPALVKEGAAAF-------- 508
P++ KL IS+A G T++++ L P E+ ++R +PN A + + A
Sbjct: 99 PTSSPKLLISIAAGWTVSSLRELLSPPQESILYILRALPNICATISQSITAIELPSEEVQ 158
Query: 509 -SRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVR 685
S T+ LT +F +G +V QMD T L GS PA++ + +E+L DGGV
Sbjct: 159 LSARTRVPQALISLTEGIFSRIGRTVQVRADQMDTFTVLGGSTPAFIAVFVEALVDGGVA 218
Query: 686 CGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII 865
GL R+ A AQ G+ ++ G+HPA+LK+ TSP G T G LE+ GFR +
Sbjct: 219 MGLGREEARMTVAQVLRGTGDLLLGGEHPALLKERGTSPGGCTMGGLCVLEEGGFRGLVG 278
Query: 866 GAVSAAV 886
AV V
Sbjct: 279 RAVREGV 285
>UniRef50_A7D089 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Opitutaceae bacterium TAV2|Rep: Pyrroline-5-carboxylate
reductase - Opitutaceae bacterium TAV2
Length = 150
Score = 104 bits (249), Expect = 5e-21
Identities = 58/144 (40%), Positives = 77/144 (53%), Gaps = 1/144 (0%)
Frame = +2
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
MPNTP + G + D L + + ++G E+ E Q+DA+T LSGSGPAY
Sbjct: 1 MPNTPGAIGAGITGWCSLHPLADADRTLVTNILNSLGKHVELAETQLDAVTGLSGSGPAY 60
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAE 820
V+ +L + G+ GLPRD A LA +T LGSA M +TG P L++ VTSP G+T
Sbjct: 61 VFEFAAALREAGIAAGLPRDTAQLLAIETLLGSARLMSQTGTEPETLRNQVTSPNGTTYA 120
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDR 892
G + FR I V AA R
Sbjct: 121 GLQRMAARDFRGLIQETVLAAKTR 144
>UniRef50_A1W308 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Comamonadaceae|Rep: Pyrroline-5-carboxylate reductase -
Acidovorax sp. (strain JS42)
Length = 288
Score = 103 bits (247), Expect = 9e-21
Identities = 79/263 (30%), Positives = 117/263 (44%), Gaps = 2/263 (0%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I FIGGG +A A+ G + GL P P + A A + G TA
Sbjct: 23 IAFIGGGNMASAIIGGLLQRGL--PAGQIEVVEPFEPARAALREKFGITAQPAAGDALAR 80
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
A + L +SVA GI ++ L ++ ++R MPNT
Sbjct: 81 AALVVWAVKPQTFKEAAAATR--AHTATALHLSVAAGIPTDSIARWLDTQ-HIVRAMPNT 137
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYM 652
PALV +G + + L ++ G V E Q+DA+TALSGSGPAYV++
Sbjct: 138 PALVGKGITGLFARPQVDPQGKALVERVIATTGQFVWVEAEEQLDAVTALSGSGPAYVFL 197
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTY 829
+E++ GV GLP A +LA T G++ + ++ + +L+ VTS G+T
Sbjct: 198 FLEAMTQAGVDMGLPPAQAYQLAVATFQGASELAARSPESAEVLRQRVTSKGGTTHAAIT 257
Query: 830 HLEKNGFRSAIIGAVSAAVDRCK 898
HL+ + I A+ AA R K
Sbjct: 258 HLQAAQVPAHFIAAMRAAEARAK 280
>UniRef50_Q5WIM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus clausii KSM-K16|Rep: Pyrroline-5-carboxylate
reductase - Bacillus clausii (strain KSM-K16)
Length = 266
Score = 102 bits (244), Expect = 2e-20
Identities = 70/259 (27%), Positives = 111/259 (42%)
Frame = +2
Query: 122 FIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXX 301
FIG GR+A A+ +G + D I + + + Q T + +
Sbjct: 6 FIGAGRMAEAIFSGLLRQPKQPFDSIYVTNRTNKERLGELAQRYAITPVDTHGAIAAKAD 65
Query: 302 XXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPA 481
L E+ P + +L I+VA GI + +E+ LP +MPNT A
Sbjct: 66 VLLLAMPPSAHGEVLSELA--PMIRGQLIITVAAGIGPSDMEAQLPEGTAAAWIMPNTAA 123
Query: 482 LVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIE 661
V + ++ G + L ++ A+G +E+ E Q+ +TA++GS PA+VY
Sbjct: 124 QVGTSISLYAFGKNVAEKQKLLVKEIVHAIGAGEELSEEQIHDLTAITGSAPAFVYEFAL 183
Query: 662 SLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEK 841
L + G+ A L GS M++TG P L+D VT+P G+T G L
Sbjct: 184 QLEKMALSYGITDKQARHLVKTMLAGSVKMLETGAPPQELRDQVTTPGGATEAGLVSLGN 243
Query: 842 NGFRSAIIGAVSAAVDRCK 898
+ F + + AV A D K
Sbjct: 244 DHFSAMLERAVHAVTDHAK 262
>UniRef50_A4R602 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 246
Score = 101 bits (243), Expect = 3e-20
Identities = 58/163 (35%), Positives = 91/163 (55%), Gaps = 7/163 (4%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED--AQLTSQ 556
+F++ GI + T+ S LP A ++R MPNTPA +++GA A G TA A+ +
Sbjct: 75 VFVTACPGIRVKTLASWLPQNAAIVRTMPNTPACIRQGATAAFAGPTVTAIPGAAEAVAA 134
Query: 557 LFKAVGT--CDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 730
L + V C E +D ++SGS PAY++ L++++ + GVR GLP D+A L Q+
Sbjct: 135 LIRHVSPSLCFVPTEDLLDVAASVSGSAPAYIFTLMQAMVEAGVRRGLPPDIAASLVKQS 194
Query: 731 TLGSAAM-VKTGDHPAM--LKDNVTSPAGSTAEGTYHLEKNGF 850
GSA + ++TG + L +V P GST++ L + GF
Sbjct: 195 AFGSAGLALQTGQLGCLEKLTSDVCVPGGSTSQAMMVLHEEGF 237
>UniRef50_Q7WJW6 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bordetella|Rep: Pyrroline-5-carboxylate reductase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 264
Score = 100 bits (239), Expect = 9e-20
Identities = 84/264 (31%), Positives = 119/264 (45%), Gaps = 5/264 (1%)
Frame = +2
Query: 122 FIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXX 301
F+G GR+ AL ++ AGL I A D A +A GA L E
Sbjct: 6 FLGYGRMGAALGEAWLRAGLLAG--IDAVDPGRDGAGLRARLVRGADELPEQAYDLVVLA 63
Query: 302 XXXXXXXXXXXXPALKEIKNLPSAK--NKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
A + ++ +P A+ +S+ G+ + L V R MPNT
Sbjct: 64 VKPAM--------AQQALRAVPPARLARACLVSIMAGVPAGALRQALQPPRPVARAMPNT 115
Query: 476 PALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYM 652
P + +G G +LF+AVG V E Q+ A+TALSGSGPAY ++
Sbjct: 116 PVMAGQGCTGLYGGDDVAPAQRAAIGRLFEAVGAAFWVDTEDQLHAVTALSGSGPAYYHL 175
Query: 653 LIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTY 829
E+LA G + GLP LA LAA+T LG+A++ + G A L+ VTSP G+T
Sbjct: 176 FSEALAQAGEQLGLPAALARSLAARTALGAASLQCEEGADFAALRREVTSPHGTTHAAIE 235
Query: 830 HLEKNG-FRSAIIGAVSAAVDRCK 898
E+ G R+ + AV A R +
Sbjct: 236 VFEQAGALRTLVRDAVRQAQARSR 259
>UniRef50_Q9FDK7 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Zymomonas mobilis|Rep: Pyrroline-5-carboxylate reductase
- Zymomonas mobilis
Length = 271
Score = 100 bits (239), Expect = 9e-20
Identities = 76/264 (28%), Positives = 111/264 (42%), Gaps = 5/264 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITA-SCHPSDVASAKAFQGLGATALFENXXXXX 292
I FIG G+++ A+ I A +ITA P + G T +
Sbjct: 4 IHFIGSGQMSEAMIRAIIKHKTASASDITAYDIRPE--REKELHDNYGITTFAKPKKNIE 61
Query: 293 XXXXXXXXXXXXXXXPALKEIKN--LPSAKNK-LFISVAMGITIATVESNLPSEARVIRV 463
LK + +AK K L +S+ G+T+A E L E + R+
Sbjct: 62 TLQKADIVVIGVRPQDDLKAVTADIAQNAKEKALIVSIVAGVTLAQFEDLLGKERAIARI 121
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
+PNT + + +S D LT + G C + E +D T GP Y
Sbjct: 122 IPNT---LTDTGLGYSGVVINNQADKALTEKFVSGFGKCLFLEESLIDIFTGFGVCGPNY 178
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAE 820
VY IE+L D GV GLPRD+A + +GS M++ +G HP L D SPAG
Sbjct: 179 VYYFIEALVDAGVLAGLPRDIAWETTMENLVGSVKMLEISGKHPRQLLDINNSPAGVGMN 238
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDR 892
+ L ++ F + + +V AAV R
Sbjct: 239 SLFALNQSDFTAGLQNSVLAAVKR 262
>UniRef50_Q9K1N1 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Neisseria|Rep: Pyrroline-5-carboxylate reductase -
Neisseria meningitidis serogroup B
Length = 263
Score = 99 bits (238), Expect = 1e-19
Identities = 59/179 (32%), Positives = 96/179 (53%), Gaps = 2/179 (1%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L +SVA G+++ T+ L R++RVMPNTP + G + + + D ++ ++
Sbjct: 83 LVLSVAAGLSVGTLSRYLGGTRRIVRVMPNTPGKIGLGVSGMYAEAEVSETDRRIADRIM 142
Query: 563 KAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
K+VG T E +M IT +SGSGPAYV+ L+++L + +R G A L+ T G
Sbjct: 143 KSVGLTVWLDDEEKMHGITGISGSGPAYVFYLLDALQNAAIRQGFDMAEARALSLATFKG 202
Query: 740 SAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+ A+ +TG+ L+ NVTS G+T E ++ AI V A V R + +++Q
Sbjct: 203 AVALAEQTGEDFEKLQKNVTSKGGTTHEAVEAFRRHRVAEAISEGVCACVRRSQEMERQ 261
>UniRef50_A6NV19 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacteroides capillosus ATCC 29799|Rep:
Pyrroline-5-carboxylate reductase - Bacteroides
capillosus ATCC 29799
Length = 253
Score = 99 bits (238), Expect = 1e-19
Identities = 70/255 (27%), Positives = 115/255 (45%), Gaps = 1/255 (0%)
Frame = +2
Query: 149 ALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXXXXXXXXXXX 328
A+ +G + GL + +++ S D A QG+ T +N
Sbjct: 4 AILDGVLKGGLLQAEQLWVSNRHEDKLERFARQGVHTTT--DNCQVAREADLVILGIKPQ 61
Query: 329 XXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAF 508
L +I + K +S++ G ++A + LP V+R MPNTP LV +G A
Sbjct: 62 MFGDVLPQIAE--QVRGKGVLSISPGYSLAWLREQLPG-CHVMRAMPNTPLLVGKGCTAL 118
Query: 509 SRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRC 688
++ E + +F + G VPE+ +DA+ A++GS PAY + + +++ G
Sbjct: 119 AQSGDVPEELFEAVKAVFSSAGEVFVVPEHLIDAVIAIAGSSPAYFFRMADAMVSAGQSL 178
Query: 689 GLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII 865
GL D ALR+AA T G+A M +++G LK V SP G+T + F +
Sbjct: 179 GLAPDDALRMAALTMEGAARMLLESGKTAGELKRQVCSPGGTTLAALTAFDDYRFEEMVN 238
Query: 866 GAVSAAVDRCKIVKK 910
A+ V R + + K
Sbjct: 239 EAMERCVRRSQELGK 253
>UniRef50_Q5HFR9 Cluster: Pyrroline-5-carboxylate reductase; n=16;
Staphylococcus|Rep: Pyrroline-5-carboxylate reductase -
Staphylococcus aureus (strain COL)
Length = 271
Score = 99 bits (238), Expect = 1e-19
Identities = 72/263 (27%), Positives = 117/263 (44%), Gaps = 2/263 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAF-QGLGATALFENXXX 286
MK+ F G G +A A+ G I++ ++I + + S+ + KAF + LG +++
Sbjct: 1 MKLVFYGAGNMAQAIFTGIINSSNLDANDIYLT-NKSNEQALKAFAEKLGVNYSYDDATL 59
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
IK K+ FIS+ GI I ++ L + V R+M
Sbjct: 60 LKDADYVFLGTKPHDFDALATRIKP-HITKDNCFISIMAGIPIDYIKQQLECQNPVARIM 118
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PNT A V S + + L KA G+ EV E + +TA++GSGPA++
Sbjct: 119 PNTNAQVGHSVTGISFSNNFDPKSKDEINDLVKAFGSVIEVSEDHLHQVTAITGSGPAFL 178
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEG 823
Y + E G + GL ++ +G++ M++ D A L+ N+TS G+T G
Sbjct: 179 YHVFEQYVKAGTKLGLEKEQVEESIRNLIIGTSKMIERSDLSMAQLRKNITSKGGTTQAG 238
Query: 824 TYHLEKNGFRSAIIGAVSAAVDR 892
L + S ++AAVDR
Sbjct: 239 LDTLSQYDLVSIFEDCLNAAVDR 261
>UniRef50_Q03V33 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Pyrroline-5-carboxylate reductase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 255
Score = 99.1 bits (236), Expect = 2e-19
Identities = 70/261 (26%), Positives = 117/261 (44%), Gaps = 1/261 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M GFIG G +A A+ G I AG+ + +S H ++AK L A
Sbjct: 1 MNYGFIGAGNMATAMIKGLIYAGIDSKNIYVSSPH----SAAKLAANLHIQAADSETIAK 56
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L+ + N + K+ ISV +TIA ++ P+ V R +P
Sbjct: 57 KCDIVIIAFLPNQ-----LRTLGNSLNLDGKIVISVLAQVTIADLDEVFPTAFNV-RSLP 110
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N + + +G+ A + + ++ + +GT + E +A++GSGPA+V
Sbjct: 111 NINSAIGKGSTALAFSKRLNEGQIEVVQNYWHLLGTTSVLDEQHFAIFSAIAGSGPAFVL 170
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGT 826
I++L G+ GL + A +AA T G+ + K+ L +NV SP GST G
Sbjct: 171 KFIDALTQAGINNGLDGESAAAIAASTVAGTTETLQKSNSDAVTLMNNVASPGGSTRAGL 230
Query: 827 YHLEKNGFRSAIIGAVSAAVD 889
+ E+N F + + A++A V+
Sbjct: 231 DNFEQNDFDTIVNSAINATVN 251
>UniRef50_A5VEU4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sphingomonas wittichii RW1|Rep: Pyrroline-5-carboxylate
reductase - Sphingomonas wittichii RW1
Length = 268
Score = 99.1 bits (236), Expect = 2e-19
Identities = 68/189 (35%), Positives = 102/189 (53%), Gaps = 6/189 (3%)
Frame = +2
Query: 344 LKEIKNLPSAKN---KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSR 514
L EI L +AK +L +SV G+ T++ ++ ++R MPN P + EG A
Sbjct: 71 LGEIAPLFAAKAGAPRLLLSVLAGVETTTLKDVFGADV-IVRAMPNLPVSIGEGVTALY- 128
Query: 515 GTKATAEDAQLTSQLFKAVGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCG 691
+ A + L ++G + V E ++ DA+TALSG GP +++ IE++A G G
Sbjct: 129 SSDADEGARNEAAGLVASLGLVEWVDEEKLFDAVTALSGCGPGFLFRFIEAMAQAGEALG 188
Query: 692 LPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 868
LP ALRLA T GSA + + + PA+L D V SP GST EG L+++ A++
Sbjct: 189 LPAGQALRLATATVKGSALLAAGSNEGPAVLADRVASPGGSTREGLNVLDRDEALKALMR 248
Query: 869 A-VSAAVDR 892
A +SAA R
Sbjct: 249 ATLSAAAQR 257
>UniRef50_A4A9D5 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Congregibacter litoralis KT71|Rep: Delta
1-pyrroline-5-carboxylate reductase - Congregibacter
litoralis KT71
Length = 272
Score = 99.1 bits (236), Expect = 2e-19
Identities = 74/268 (27%), Positives = 120/268 (44%), Gaps = 2/268 (0%)
Frame = +2
Query: 122 FIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXXXX 301
FIG G ++ ++ G ++ G+ P ++AS +PS +A + LG T L +
Sbjct: 8 FIGAGNMSRSIIGGLVAGGV-DPRSVSAS-NPSK-GPLEALEKLGLTELGHSNVEVVGNA 64
Query: 302 XXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPA 481
A+ E + L ISVA G+T + L S+ V+R MPNTP+
Sbjct: 65 DVVVLGVKPKLIQAVCEELAPVIRDDHLVISVAAGVTADNIHRWLGSKGEVVRCMPNTPS 124
Query: 482 LVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQM-DAITALSGSGPAYVYMLI 658
+ GA+ + Q ++ AVG V E + A+TA++GS PAY + +
Sbjct: 125 QIGAGASGLYARASVGDANRQRAEEVMSAVGVVRWVQEEPLLHAVTAVAGSAPAYFFQFM 184
Query: 659 ESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHL 835
E++ R GL + A L AQT +G+ M+ GD A L+ V SP G+T
Sbjct: 185 EAMIAEAGRMGLDEESARTLCAQTCIGAGRMLAEGDVDAAELRRRVCSPNGATERAVDAF 244
Query: 836 EKNGFRSAIIGAVSAAVDRCKIVKKQLN 919
G + A+ A R + + ++ +
Sbjct: 245 SAGGLDKLVSKAMEACAARSEELAQEFS 272
>UniRef50_Q5ZP97 Cluster: Pyrroline carboxylate reductase-like
protein; n=1; Angiococcus disciformis|Rep: Pyrroline
carboxylate reductase-like protein - Angiococcus
disciformis
Length = 358
Score = 98.7 bits (235), Expect = 3e-19
Identities = 79/264 (29%), Positives = 120/264 (45%), Gaps = 3/264 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
+GFIGGG +A AL GLA P + D + + + +
Sbjct: 84 LGFIGGGVMAEALIGAVTGGGLAAPGTLLVG--EVDEERRRVLREQYGVEVTADNLAAAD 141
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
L++++ ++ + +S+ G + T+ L V+R MPNT
Sbjct: 142 AELVVLAVKPQHLGVVLQQLRG-QLREDTIVVSIIAGARLQTLCEGL-EHPLVVRAMPNT 199
Query: 476 PALVKEGAAAFSRGTKATAEDAQL-TSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVY 649
PA V++ AA F + +E A + L A+GT EV E ++ T L+G PA+VY
Sbjct: 200 PARVRK-AATFWIPSAGLSEPALVRVRSLLGALGTEVEVADEAGVEMATGLAGPMPAFVY 258
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGT 826
LIE+ D GV GLPRD A ++ GS ++ ++ + PA L+ VTSP G+T G
Sbjct: 259 FLIEAFIDAGVALGLPRDQATLATVESMRGSLELLHRSQESPAALRKQVTSPGGATLAGL 318
Query: 827 YHLEKNGFRSAIIGAVSAAVDRCK 898
E G R A+ AV A R +
Sbjct: 319 KVFESAGVRDAMDAAVRAVHARAQ 342
>UniRef50_A6VSQ3 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Marinomonas|Rep: Pyrroline-5-carboxylate reductase -
Marinomonas sp. MWYL1
Length = 275
Score = 98.7 bits (235), Expect = 3e-19
Identities = 59/176 (33%), Positives = 86/176 (48%), Gaps = 2/176 (1%)
Frame = +2
Query: 377 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 556
++LFISVA GI + ++ L V+R MPNTP+ + G +E S+
Sbjct: 89 DQLFISVAAGIELDSLAHWLGKPVAVVRSMPNTPSQLGAGMTGLIANEHTNSEQKNWVSE 148
Query: 557 LFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 733
LF ++G V E M +T+LSGS PAY + IE++ GL + LA+
Sbjct: 149 LFSSIGNSVWVENEVHMHTVTSLSGSAPAYFFRFIEAMVKNAKEQGLDEATSRELASNAM 208
Query: 734 LGSAAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
G+A MV D P A L+ N+TSP G+T + E + A+ A V+R K
Sbjct: 209 FGAARMVMELDEPIAQLRKNITSPKGTTEQALLSFEAADIDKIVADAMMACVNRSK 264
>UniRef50_Q0BPP7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
Pyrroline-5-carboxylate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 280
Score = 97.9 bits (233), Expect = 5e-19
Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 3/177 (1%)
Frame = +2
Query: 371 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 550
A + +F+SV G+T A + L +A ++R MPNTP+ + +G G L
Sbjct: 90 AGHSVFLSVMAGLTQAGLAGILGEQAAIVRSMPNTPSAIGKGFTMAHAGPHVDGAQRSLC 149
Query: 551 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 727
L +AVGT E ++ A TA+SG GPAYV+++ E L + + GL DLA +A Q
Sbjct: 150 HTLLEAVGTVAWAEQETELLAATAISGGGPAYVFLIAELLENCALEQGLEPDLARSMARQ 209
Query: 728 TTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHL-EKNGFRSAIIGAVSAAVDR 892
T +G+A +++ + A+L+ VTSP G+T + L ++ SA AV AA+ R
Sbjct: 210 TVIGAALLLEREEADAAVLRRAVTSPGGTTEQALKILMAEDALPSAFSRAVKAAIKR 266
>UniRef50_UPI0000E87E64 Cluster: pyrroline-5-carboxylate reductase;
n=1; Methylophilales bacterium HTCC2181|Rep:
pyrroline-5-carboxylate reductase - Methylophilales
bacterium HTCC2181
Length = 269
Score = 97.5 bits (232), Expect = 6e-19
Identities = 69/267 (25%), Positives = 124/267 (46%), Gaps = 2/267 (0%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN 277
+I+ KI F+GGG +A A+ G I+ G + + + + + + +
Sbjct: 1 MIKQKKIIFVGGGNMAKAIIYGLINNGYTQSNLFVIDPSADQLNTISSDYSVNVSTSMCQ 60
Query: 278 XXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVI 457
++K+ N +L IS+A GI+I + L + ++
Sbjct: 61 LNGGEIIILATKPHHIKSICESIKDNLN-----QQLIISIAAGISIKNISKWLGNYKHIV 115
Query: 458 RVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSG 634
R MPN A ++ A + + + +F +G + E+++DA+T++SGSG
Sbjct: 116 RTMPNLVAQIQRSMTALCGAEELSQDHKNDAQSIFNTIGKILWLNDEFKIDAVTSISGSG 175
Query: 635 PAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGS 811
PAYV+ ++SL + G + GL RD A LA +T +GSA M ++ + L +NV+S G+
Sbjct: 176 PAYVFYFLDSLIEAGEKVGLSRDEAEYLAHETLIGSAIMSESYLNDLGTLINNVSSKGGT 235
Query: 812 TAEGTYHLEKNGFRSAIIGAVSAAVDR 892
T + L+ + I AV++A R
Sbjct: 236 TEQAISVLKNKDLKEIIGLAVASAFKR 262
>UniRef50_Q8D3C2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Wigglesworthia glossinidia endosymbiont of Glossina
brevipalpis|Rep: Pyrroline-5-carboxylate reductase -
Wigglesworthia glossinidia brevipalpis
Length = 291
Score = 97.1 bits (231), Expect = 8e-19
Identities = 69/266 (25%), Positives = 121/266 (45%), Gaps = 4/266 (1%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KI FIG G++A ++ G I++ P + C P + + + + EN
Sbjct: 19 KITFIGSGKIAESMIIGLINSKY--PSDCIFVCSPDEKSRSAISERYLVKNFKENLIGSN 76
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPS-EARVIRVMP 469
+EIKNL + +NKL ISVA GI I +++ L + +A + R MP
Sbjct: 77 IGEIIVLAVKPNIIPIVCEEIKNLTNIENKLIISVAAGININSIKKYLNNKKALIARAMP 136
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYV 646
NTP LV+EG + Q+F +G + E +++ I + S S AY
Sbjct: 137 NTPVLVREGVIGLYAKKDIRTIHEKTIEQIFNRIGKIFWLSQEKEINYIISASSSATAYF 196
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAM--LKDNVTSPAGSTAE 820
+++++++ + G+ + + + QT G+ + + + LK ++TS G+T
Sbjct: 197 FLMMDAMKNTAENIGINKSYSREVILQTAKGAIVLAEHFSEISFNTLKKHITSKKGTTEA 256
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDRCK 898
+KN FR + ++ AAV R K
Sbjct: 257 ALNSFKKNNFRKIVEISMKAAVSRAK 282
>UniRef50_Q0PQR2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep:
Pyrroline-5-carboxylate reductase - Endoriftia
persephone 'Hot96_1+Hot96_2'
Length = 186
Score = 97.1 bits (231), Expect = 8e-19
Identities = 55/142 (38%), Positives = 80/142 (56%), Gaps = 6/142 (4%)
Frame = +2
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPA 640
MPNTPA+++ GA + +AVG V E Q+DA+TALSGSGPA
Sbjct: 42 MPNTPAMIQAGATGLHASAGVNDAQRNQAESILRAVGLTRWVEDEAQIDAVTALSGSGPA 101
Query: 641 YVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTA 817
Y ++++E++ V GL + A L QT LG+A M +++ D PA L+ VTSP G+T
Sbjct: 102 YFFLVMEAMEAAAVELGLDSESARLLTLQTALGAARMAIESRDAPATLRQKVTSPGGNTE 161
Query: 818 EGTYHLEKNG----FRSAIIGA 871
+ LE+ G F+ A++GA
Sbjct: 162 KALGILEEGGLRDLFKDALLGA 183
>UniRef50_Q5ZTZ3 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Legionella pneumophila|Rep: Pyrroline-5-carboxylate
reductase - Legionella pneumophila subsp. pneumophila
(strain Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 262
Score = 95.9 bits (228), Expect = 2e-18
Identities = 55/147 (37%), Positives = 78/147 (53%), Gaps = 2/147 (1%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L ISVA G+++ V+R MPNTPA+V A + + + QLF
Sbjct: 84 LLISVAAGLSLTWFAKYCKKGQAVVRTMPNTPAIVGFAATSMIANEFVNEKQKKWAEQLF 143
Query: 563 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
++G D V E MD +TALSGSGPAYV++ +E++ + GV+ GL +A A QT G
Sbjct: 144 SSIGITDWVKDEEDMDTLTALSGSGPAYVFLFLEAMINAGVQLGLEETVAKHFAIQTFSG 203
Query: 740 SAAMVKTGD-HPAMLKDNVTSPAGSTA 817
S + + L+ VTSP G+TA
Sbjct: 204 SLQLAQHSQLSLTELRKKVTSPGGTTA 230
>UniRef50_Q11WK0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep:
Pyrroline-5-carboxylate reductase - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 268
Score = 95.5 bits (227), Expect = 2e-18
Identities = 71/265 (26%), Positives = 118/265 (44%), Gaps = 2/265 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKI +GGG + A F+S + DE+ D + Q G +L +
Sbjct: 1 MKIAILGGGNMGMTYAKAFVSRKIVSKDELLI-IEKHDEKREQLKQE-GVASLSADIDDS 58
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L E +N++ +S+ GI IA +++ L + V+R MP
Sbjct: 59 IKNYDILIVAVKPQDFRVLSETLKKYLTENQMILSIMAGIQIAQIQTLLEHK-NVVRAMP 117
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYV 646
NTPA + G AF+ A+ E+ + L + G + E +DA+TALSGSGPAY
Sbjct: 118 NTPAQLGFGITAFTVAKDASFENISVVDMLLETTGKAIFMKDETMLDAVTALSGSGPAYF 177
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEG 823
Y +++++ + G + G+ ++A L +T +G+ ++ L V S G+T
Sbjct: 178 YYIVQNMIEAGKQMGVDENVAGMLVKETMMGAFQILNHSKSSIDELIAMVASKGGTTEAA 237
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCK 898
L++ + II A+ A R K
Sbjct: 238 LNTLKQREVGAHIIEALKNAEKRAK 262
>UniRef50_A6QB49 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Epsilonproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Sulfurovum sp. (strain NBC37-1)
Length = 252
Score = 94.7 bits (225), Expect = 4e-18
Identities = 65/186 (34%), Positives = 99/186 (53%), Gaps = 1/186 (0%)
Frame = +2
Query: 344 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 523
++E+ K ++ SV G ++ ++ ++ S+A V+R MPN A V + G
Sbjct: 71 VEEVGKQLKGKARVLFSVLAGTSLEKLKKHIKSKA-VVRAMPNLAASVGASMTTLT-GDH 128
Query: 524 ATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 700
+A+ L AVG T E ++D TAL+GSGPAY+ ++ E+LADG V+ GL R
Sbjct: 129 RFQREAE---SLLGAVGDTLWLNSEKEIDIATALAGSGPAYLALVAEALADGAVKQGLKR 185
Query: 701 DLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 880
+ A+ G +++ HPA+LKD V SP G+TA G LE+ RSA + A+
Sbjct: 186 EDAMAAMRGLFNGFGKLIQE-VHPALLKDGVMSPGGTTAAGYGALEEGNVRSACMDAIEE 244
Query: 881 AVDRCK 898
A R K
Sbjct: 245 AYKRAK 250
>UniRef50_A7EEE1 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 94.7 bits (225), Expect = 4e-18
Identities = 55/177 (31%), Positives = 92/177 (51%), Gaps = 7/177 (3%)
Frame = +2
Query: 377 NKLFISVAMGITIATVES---NLPSEAR---VIRVMPNTPALVKEGAAAFSRGTKATAED 538
NKL ISV G T ++ N S+ + +R MPN A +KE + S G++ +
Sbjct: 141 NKLIISVLAGSTTEQLKEFAFNGSSDTKGCSFVRSMPNLGAQIKESSTVISTGSETISSK 200
Query: 539 AQLTSQ-LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 715
+ + +F+++G VP+ L+G PA+ + + DG V G+ RD A
Sbjct: 201 HEKAMEWIFQSIGQYTYVPDNVFQVAGVLAGCTPAWFLTAFDGILDGAVSEGMKRDTAKE 260
Query: 716 LAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 886
+ A + L +A +++ G+HPA+L++ V+SP G+T +G +EK G RS A +V
Sbjct: 261 ILAGSMLAAAKLIQNGEHPAVLREKVSSPKGTTIQGLKTIEKGGVRSTYCDATIDSV 317
>UniRef50_A6RSV4 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 314
Score = 94.7 bits (225), Expect = 4e-18
Identities = 56/177 (31%), Positives = 92/177 (51%), Gaps = 7/177 (3%)
Frame = +2
Query: 377 NKLFISVAMGITIATVES---NLPSEAR---VIRVMPNTPALVKEGAAAFSRGTKATAED 538
NKL ISV G T ++ N S+ + +R MPN A +KE + S GT+ +
Sbjct: 129 NKLVISVLAGSTTEQLKEFAFNGSSDTKGCAFVRSMPNLGAQIKESSTVISTGTETISPK 188
Query: 539 AQLTSQ-LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 715
+ + +F+++G VP+ L+G PA+ + + DG V G+ RD A
Sbjct: 189 YEEAMKWIFQSIGQYTYVPDNVFQVAGVLAGCTPAWFLTAFDGILDGAVSEGMRRDTATE 248
Query: 716 LAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 886
+ A + L +A +++ G+HPA+L++ V+SP G+T +G +EK G RS A +V
Sbjct: 249 ILAGSMLAAAKLIQNGEHPAVLREKVSSPKGTTIQGLKTIEKGGVRSTYCDATIDSV 305
>UniRef50_Q2PIP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Trichocomaceae|Rep: Pyrroline-5-carboxylate reductase -
Aspergillus oryzae
Length = 292
Score = 93.9 bits (223), Expect = 8e-18
Identities = 53/184 (28%), Positives = 88/184 (47%), Gaps = 9/184 (4%)
Frame = +2
Query: 374 KNKLFISVAMGIT------IATVESNLP---SEARVIRVMPNTPALVKEGAAAFSRGTKA 526
+ KL +S+ GIT +A E + P S + +R MPN A ++E ++ G+
Sbjct: 104 QGKLVLSIMAGITTKALNILALGEDSAPDNESALQCVRAMPNMAAKIREAVTLYTAGSGT 163
Query: 527 TAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 706
T E+ ++ S +F VG +PE D G + + + I+ L D V G+ R
Sbjct: 164 TKENLEIASWVFSQVGEAHRIPESSFDICAVSVGCAGSLLLLAIDGLLDAAVAEGVKRPD 223
Query: 707 ALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 886
L + +G +V GDH ++L++ + SP G + LEK G R+A A+ AA
Sbjct: 224 VQNLVVNSAIGMMKLVPAGDHVSVLREKIASPGGCSIRALLELEKLGVRAAFTTAIMAAA 283
Query: 887 DRCK 898
++ K
Sbjct: 284 EKSK 287
>UniRef50_A2BJN9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Hyperthermus butylicus DSM 5456|Rep:
Pyrroline-5-carboxylate reductase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 247
Score = 93.9 bits (223), Expect = 8e-18
Identities = 60/181 (33%), Positives = 97/181 (53%), Gaps = 2/181 (1%)
Frame = +2
Query: 380 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 559
K +SV G+ ++ ++ L A V R MPN ++ G + + + A L +
Sbjct: 58 KPVVSVMAGVPVSLLQKVLKG-AEVYRAMPNLN--IRVGRSLTALYSPPNARHYGLVRRA 114
Query: 560 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
GT +VPE +DA TA++GSGPA V +++L + GLPR +A R+AA+
Sbjct: 115 LSCFGTVYDVPEEFIDAWTAVAGSGPALVAEFLDALVLAALAVGLPRSIARRVAAELLES 174
Query: 740 SAA-MVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+A +++ D HP +L+D V +PAG+T LE GF+SA+I AV A R + ++
Sbjct: 175 TARYLLENPDVHPGVLRDEVITPAGTTIAAIRTLESRGFKSAVIDAVRDATLRAGEIARE 234
Query: 914 L 916
+
Sbjct: 235 I 235
>UniRef50_Q9AAU9 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Caulobacter|Rep: Pyrroline-5-carboxylate reductase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 260
Score = 92.7 bits (220), Expect = 2e-17
Identities = 64/179 (35%), Positives = 93/179 (51%), Gaps = 3/179 (1%)
Frame = +2
Query: 371 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAA-FSRGTKATAEDAQL 547
A + + +S+A G+ A + RV RVMP T + +GAA+ ++ +A A L
Sbjct: 82 APDAVIVSIAAGVRAADISQAFGGR-RVARVMPTTAVAIGQGAASLYADDAEALARARAL 140
Query: 548 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 727
+ L + E M A TA+SGS PAY+Y IE+L G GL + RLA
Sbjct: 141 FAPL---AAVAELASEDLMHAATAVSGSAPAYLYAFIEALEAAGAAQGLDPAQSARLARA 197
Query: 728 TTLGSAA-MVKTGDHPAMLKDNVTSPAGSTAEG-TYHLEKNGFRSAIIGAVSAAVDRCK 898
T +G+AA M ++G+ PA L+ VTSP G+TA + + GF + A+ AAV R K
Sbjct: 198 TIIGAAALMAQSGEEPAELRKQVTSPGGTTAAALSVLMGAGGFGDLLPKALDAAVARSK 256
>UniRef50_Q1VVL6 Cluster: Pyrroline-5-carboxylate reductase; n=9;
Bacteroidetes|Rep: Pyrroline-5-carboxylate reductase -
Psychroflexus torquis ATCC 700755
Length = 266
Score = 92.7 bits (220), Expect = 2e-17
Identities = 73/270 (27%), Positives = 116/270 (42%), Gaps = 2/270 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGL-GATALFENXXX 286
MKI IG G L ++A G ++ +T D+ + F G T EN
Sbjct: 1 MKIAIIGTGNLGKSIAKGLLTNNAITSLYLTKR----DLNDIQEFDGYKNVTLTTENLEA 56
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
L +IK + +N + IS G I+ +E + ++ +IR M
Sbjct: 57 VKQSDILIFAVQPTHFEQILIDIKPYLT-ENHILISTITGFLISKIEGLVGNDQFIIRAM 115
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
PNT V + K A+ ++ +F +G +PE QM A T + SG A+
Sbjct: 116 PNTAIAVGKSMTCLCSNEKG-AKRIKVAEAIFNRLGHTLAIPESQMQAATVICASGIAFW 174
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKT-GDHPAMLKDNVTSPAGSTAEG 823
LI + ++ G A LA T+ G+A ++ T G HP D VT+P G T EG
Sbjct: 175 MRLIRASTQAAIQLGFDAKEAQELAMYTSEGAANLLITNGLHPEEEIDRVTTPKGCTIEG 234
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
+E G S++I + A+ ++ +KK+
Sbjct: 235 LNEMEHKGLSSSLIQGMVASFNKINNIKKE 264
>UniRef50_Q8A6I2 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Bacteroides|Rep: Pyrroline-5-carboxylate reductase -
Bacteroides thetaiotaomicron
Length = 266
Score = 92.3 bits (219), Expect = 2e-17
Identities = 66/259 (25%), Positives = 112/259 (43%), Gaps = 1/259 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKI IG G + A+A L +I S +D Q + EN
Sbjct: 1 MKITIIGAGNIGSAVAACLAKGHLYNEKDIIISTPHTDKLENLHKQFPAIRIMTENQYAI 60
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L ++ ++ ++ +S+ GI+I+ + +E + RV+P
Sbjct: 61 SEADIIILAVKPCIVDEVLSPLR---FSRTQILVSLVTGISISHLAHLSETEMPIFRVVP 117
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
N A+ + + KA E QL Q F+ G C E Q+D I+AL+ SG A+
Sbjct: 118 NI-AITEHSSLTLITSRKAGKEHQQLIKQTFEEGGKCLFAEEKQLDIISALTSSGIAFAL 176
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGT 826
I + G+ G+ + A+R+ A + G+ ++ D HP + + +P G+T +G
Sbjct: 177 KYIHAAMQAGIELGISAEDAMRMTAYSMEGATELILNHDTHPLLEIEKAATPGGATIKGL 236
Query: 827 YHLEKNGFRSAIIGAVSAA 883
LE GF SA+I A+ ++
Sbjct: 237 NELEHRGFTSAVIHAIKSS 255
>UniRef50_UPI00015BCA3C Cluster: UPI00015BCA3C related cluster; n=1;
unknown|Rep: UPI00015BCA3C UniRef100 entry - unknown
Length = 247
Score = 91.9 bits (218), Expect = 3e-17
Identities = 54/187 (28%), Positives = 102/187 (54%), Gaps = 2/187 (1%)
Frame = +2
Query: 344 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 523
L +K L + K +S+ GI+++ ++ ++ +A + R+MPN + K+G F
Sbjct: 68 LTSLKGL-NFNEKSLVSMLAGISVSRLKEHI-KDAYITRIMPNLAVIYKKGVIGFY---- 121
Query: 524 ATAEDAQ--LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 697
+EDA+ + + + +G E+ E DA TA+ GSGPA++ ++E++ G+ GL
Sbjct: 122 --SEDAKKDVIKSILQHLGKVYELDEKHFDAFTAIGGSGPAFIASVVEAMRLSGIYMGLN 179
Query: 698 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 877
+D++ LA T G+ ++K + ++ V+SPAG+T EG Y++EK G + ++
Sbjct: 180 KDISYDLAIATIEGTLEILKAYNEEELVL-KVSSPAGTTIEGIYNIEKTGLKGILMETFI 238
Query: 878 AAVDRCK 898
A + K
Sbjct: 239 KAYQKSK 245
>UniRef50_Q7YYR6 Cluster: Pyrroline-5-carboxylate reductase,
possible; n=3; Cryptosporidium|Rep:
Pyrroline-5-carboxylate reductase, possible -
Cryptosporidium parvum
Length = 284
Score = 91.9 bits (218), Expect = 3e-17
Identities = 74/285 (25%), Positives = 126/285 (44%), Gaps = 14/285 (4%)
Frame = +2
Query: 98 LIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITA-SCHPSDVASAKA-FQGLGATALF 271
+I KIGFIG G +A A+ +GF+S+ K D+I + + + S K F G+ +
Sbjct: 1 MISERKIGFIGCGNIANAIISGFLSSEKIKSDQIFLFDSNKNSLESLKREFSGINISENL 60
Query: 272 ENXXXXXXXXXXXXXXXXXXXXPALKEIKNLP-----SAKNKLFISVAMGITIATVESNL 436
++ L EI NL + +K+ ISV G TI+ +
Sbjct: 61 QSLVGNSELIFICVKPHILSQI--LSEINNLNIESDLKSGDKVLISVCAGKTISDILKEF 118
Query: 437 PS-EARVIRVMPNTPALVKEGAAAFSRG-----TKATAEDAQLTSQLFKAVGTCDEVPEY 598
S E IRVMPN + +G + TK ++ ++ + GT ++ E
Sbjct: 119 QSNEIHCIRVMPNLTLSICQGTWLYYENPVAHFTKYKQNNSNEIIEILSSCGTVYKINED 178
Query: 599 QMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPA 775
T++SG GP Y + G++ G+P DLA +L +T G++ ++ ++ P
Sbjct: 179 IFSHCTSISGCGPGYFSNIAHHFIQSGIKIGIPEDLARKLVIETMYGTSKLLFESSIDPQ 238
Query: 776 MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
+ + V++P GST G LE + +++DRC + K
Sbjct: 239 VFQSKVSTPGGSTQAGIDILEDRLIGKIFQDCLYSSLDRCNQLSK 283
>UniRef50_Q0UG51 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 291
Score = 91.9 bits (218), Expect = 3e-17
Identities = 53/177 (29%), Positives = 93/177 (52%), Gaps = 3/177 (1%)
Frame = +2
Query: 353 IKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATA 532
I++ A + +++ GITI+ +++ LP+ +IR MPNTP V +GA A T+
Sbjct: 102 IESFCKANPPVVLTMCPGITISQLQTWLPANYPIIRSMPNTPVAVGQGATALFANKFVTS 161
Query: 533 EDAQLTSQLFKAVGTCDEVPEYQ--MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 706
++F V C E + +D + ++SGSGPAY++ + +++ D + GLP
Sbjct: 162 GSINEIKKVFLNVSPCVECLNCEDLLDVVASVSGSGPAYLFYMAQAIVDAAIAKGLPEKQ 221
Query: 707 ALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 874
A L Q+ +G++ + + + L D+V P GST + L+ +G AI+ AV
Sbjct: 222 AKSLVIQSVIGASLLAQRMPQSLSELLDDVCVPGGSTEKAMATLDLHGANDAILKAV 278
>UniRef50_Q0CFR0 Cluster: Predicted protein; n=3; Aspergillus|Rep:
Predicted protein - Aspergillus terreus (strain NIH
2624)
Length = 304
Score = 91.9 bits (218), Expect = 3e-17
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = +2
Query: 395 VAMGITIATVESNLPSEAR-VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAV 571
+A I A+ ++ S+AR ++R MPN A +++ +AE A L + +F+ V
Sbjct: 136 IAACIDHASPTADAGSDARNIVRAMPNVAARLRQSMTIIEADPALSAERAALLTWMFEQV 195
Query: 572 GTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM 751
G V Q DA L G+ A + ++ L DG V G+ R A +AAQ G AA+
Sbjct: 196 GHVKYVAAEQFDAAGMLVGASMAMFTVPLDGLLDGCVVEGIRRPEAQEMAAQVLQGMAAL 255
Query: 752 VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
+K G HPA+L++++ SP G T +G +E+ G R+A + D K
Sbjct: 256 LKDGAHPAVLRESIASPRGCTIQGLMTVERRGVRAAFADGMIDGTDHLK 304
>UniRef50_UPI0000E1F031 Cluster: PREDICTED: similar to
Pyrroline-5-carboxylate reductase family, member 2
isoform 1; n=2; Catarrhini|Rep: PREDICTED: similar to
Pyrroline-5-carboxylate reductase family, member 2
isoform 1 - Pan troglodytes
Length = 253
Score = 91.1 bits (216), Expect = 5e-17
Identities = 67/175 (38%), Positives = 88/175 (50%), Gaps = 3/175 (1%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPS---EARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 553
+ +S A G+TI++VE L + +VIR M NTP +V+EGA ++ GT A ED QL
Sbjct: 55 IVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVREGATVYATGTHALVEDGQLLE 114
Query: 554 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 733
QL +VG C EV E D I A++G L+ G G AA+
Sbjct: 115 QLMSSVGFCTEVEE---DLIDAVTG------------LSGSGPAYG---------AAKML 150
Query: 734 LGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
L S HP LKDNV SP G+T + LE GFRS +I AV A+ R +
Sbjct: 151 LDSE------QHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTR 199
>UniRef50_A7JJ83 Cluster: Pyrroline-5-carboxylate reductase; n=11;
Francisella tularensis|Rep: Pyrroline-5-carboxylate
reductase - Francisella tularensis subsp. novicida
GA99-3549
Length = 274
Score = 90.6 bits (215), Expect = 7e-17
Identities = 71/266 (26%), Positives = 117/266 (43%), Gaps = 3/266 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASA-KAFQGLGATALFENXXX 286
MKI FIGGG +A A+ G S G D I + + K + +T+L
Sbjct: 1 MKICFIGGGNMAAAMIAGMTSHGYKSQDIIVFDRNEHKCLNLIKKYNINTSTSLLNTIKL 60
Query: 287 XXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 466
+K I++ ++ ++ ++VA GI + E E R +
Sbjct: 61 ADILILAIKPQNMFEL---IKNIRDTVTS-TQVIVTVAAGIQTSAYEKLFNKEISFARTI 116
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAY 643
PNTP+ + GA A+ L + + +G V E ++D I A++ SGPAY
Sbjct: 117 PNTPSSLGYGATGIFFNKVIAADKKDLVIDIMQTMGVVTVVEDEKEIDIIAAIASSGPAY 176
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAE 820
+ +E + + V+ GL + A +L QT LG+A M + T ++ + L+ NVTS G T E
Sbjct: 177 YFQFMEHMVEAVVKQGLDKKQAEKLVVQTCLGAAQMALNTNENMSELRKNVTSKKGITYE 236
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDRCK 898
E+ + A+ A + R +
Sbjct: 237 ALNIFEQFNLGGIVDKAIQANIARAQ 262
>UniRef50_A7C3U2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Beggiatoa sp. PS|Rep: Delta
1-pyrroline-5-carboxylate reductase - Beggiatoa sp. PS
Length = 192
Score = 89.4 bits (212), Expect = 2e-16
Identities = 63/187 (33%), Positives = 94/187 (50%), Gaps = 3/187 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
I FIGGG +A +L G + G++ D+I + S+ +A+ L+ +
Sbjct: 6 ITFIGGGNMATSLIGGLLETGVSS-DKIRVADPESEPLAAQF-----PVQLYSDNIKAIE 59
Query: 296 XXXXXXXXXXXXXXPAL-KEIKNLPSAKNKLFISVAMGITIATVESNLPSE-ARVIRVMP 469
P + K I LFIS+A GI IA + L ++ ++RVMP
Sbjct: 60 GAEIIVLAVKPQVLPEIAKSIATAMPTSPPLFISIAAGIRIADLAHWLGTQPVPIVRVMP 119
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYV 646
NTPALV+ GA+A G + +L + ++VG T E QMDA+TALSGSGPAY
Sbjct: 120 NTPALVRSGASALYAGQHVSDFQHELAENILRSVGLTVWLSDEKQMDAVTALSGSGPAYF 179
Query: 647 YMLIESL 667
++++E L
Sbjct: 180 FLIMEML 186
>UniRef50_Q1GX51 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sphingopyxis alaskensis|Rep: Pyrroline-5-carboxylate
reductase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 286
Score = 88.6 bits (210), Expect = 3e-16
Identities = 56/171 (32%), Positives = 93/171 (54%), Gaps = 3/171 (1%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
+S+ G+++A + + P+ +R++PN A + G +A + +A D + L
Sbjct: 107 LSILAGVSLADLAARFPAAKAQVRILPNLAARIGAGVSAVASSGEA---DMAAVTALLDP 163
Query: 569 VGTCDEVPEYQ-MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 745
+GT + + MD +TA +GSGPA+V+ LIES A G R GL + AL+LA T G+
Sbjct: 164 LGTIVALADDSTMDLVTAFTGSGPAFVFRLIESYAAAGERLGLSAEDALKLATATFGGAT 223
Query: 746 AMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAAVDR 892
A++ +G+ P L V S G+T G L+ +G +A++ + AA DR
Sbjct: 224 ALLADSGEKPGTLIAQVASKGGTTQAGLDVLDSDGQLAALLTNVLRAARDR 274
>UniRef50_A6LE67 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteroidales|Rep: Pyrroline-5-carboxylate reductase -
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701
/ NCTC11152)
Length = 267
Score = 88.6 bits (210), Expect = 3e-16
Identities = 66/267 (24%), Positives = 109/267 (40%), Gaps = 9/267 (3%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M+I IG G + A+A G + K +IT + + +N
Sbjct: 1 MRISIIGSGNIGGAIARGLAKGTMFKASDITCTAQSDETLEKMRKIDPDFILTHDNVEAA 60
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA------- 448
+ EIK++ + ++ +SVA G+T + + L
Sbjct: 61 RNADIIIIAVKPWRVEMIIDEIKSVLDFEKQIIVSVAAGVTFDLLNTYLTKNTDFDCLAT 120
Query: 449 -RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALS 625
+ R+MPNT A+ + F A+ E L +F +G V E M A TAL+
Sbjct: 121 PTIFRIMPNT-AIEVMSSMTFVSARNASKEQTDLIIHIFNELGNAMLVEERLMGAGTALA 179
Query: 626 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSP 802
SG A+ I + +GGV G A + T G+ +++ +P M D VT+P
Sbjct: 180 SSGIAFALRYIRAAIEGGVELGFYPKQAQEIVVHTVKGAVDLLLENKSNPEMEIDKVTTP 239
Query: 803 AGSTAEGTYHLEKNGFRSAIIGAVSAA 883
G T +G +E +GF S++I + A+
Sbjct: 240 GGITIKGLNEMELSGFTSSVIRGLKAS 266
>UniRef50_A0M2T1 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Flavobacteriaceae|Rep: Pyrroline-5-carboxylate reductase
- Gramella forsetii (strain KT0803)
Length = 268
Score = 88.6 bits (210), Expect = 3e-16
Identities = 53/184 (28%), Positives = 95/184 (51%), Gaps = 2/184 (1%)
Frame = +2
Query: 347 KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 526
+E+K++ + K+++F+S+ G+TI ++ L + +V+R MPN PA V +G +++ +
Sbjct: 79 EEMKSMVN-KDQIFVSLMAGVTINKIQEGLGVK-KVVRSMPNLPAQVGKGVTSYTESKEV 136
Query: 527 TAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 703
+ + + L G V E +DA T +SGSGPAYV+ + S+ + ++ G ++
Sbjct: 137 SRVELLMVRNLLDTTGESIHVENENYIDASTGISGSGPAYVFYFMNSMLEAALKMGFSKN 196
Query: 704 LALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 880
+ L +QT G+ + D P D V S G+T ++ N + I A A
Sbjct: 197 DSKVLVSQTFEGAVELFNQNDLSPDTWMDRVASKGGTTRAALDSMDDNNVKELIKDAAYA 256
Query: 881 AVDR 892
A DR
Sbjct: 257 AFDR 260
>UniRef50_Q18J37 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Halobacteriaceae|Rep: Pyrroline-5-carboxylate reductase
- Haloquadratum walsbyi (strain DSM 16790)
Length = 258
Score = 88.6 bits (210), Expect = 3e-16
Identities = 60/169 (35%), Positives = 94/169 (55%), Gaps = 1/169 (0%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
++ A G+ + V + ++A VIR+MPN A ++E AAA + A + L+
Sbjct: 86 MTAAAGVERSFVSNQ--TDATVIRLMPNLAASLREMAAAVAWDEPDPAVETMLSD----- 138
Query: 569 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 748
+G+ + E M+ TAL+GSGPA+VY LI+S+ ++ GL + A LA QT +G+A
Sbjct: 139 LGSYVVIDETHMNIATALNGSGPAFVYYLIQSMQTRAIKEGLDKSDAQTLAIQTFIGAAE 198
Query: 749 MVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
MV+ D P L D V SP G+T EG L + + + A++AA +R
Sbjct: 199 MVRAADEPIESLIDAVCSPNGTTIEGMNVLFDSNVDAEVGDALTAATER 247
>UniRef50_Q5FRU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Gluconobacter oxydans|Rep: Pyrroline-5-carboxylate
reductase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 259
Score = 87.0 bits (206), Expect = 9e-16
Identities = 65/184 (35%), Positives = 88/184 (47%), Gaps = 8/184 (4%)
Frame = +2
Query: 365 PSAKNKLFISVAMGITIATVESNLP---SEARVIRVMPNTPALVKEGAAAFSRGTKATAE 535
P N +SV G T A + ++ V+R MPNTP+ V G + AT E
Sbjct: 72 PRMSNAAILSVMAGRTCAALSDAARLAGADIPVLRAMPNTPSAVGAGISGLYAAPSATPE 131
Query: 536 DAQLTSQLFKAVGTCDEVP---EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 706
+ L AVG D VP E + +TA+SGSGPAYV++L E L G + GL +
Sbjct: 132 QKSICHDLLFAVG--DVVPVEKEADLSVVTAISGSGPAYVFLLAELLEKAGQQHGLSPTI 189
Query: 707 ALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEK-NGFRSAIIGAVSA 880
A RLA T G+ M+ D L+ VTSP G+TA L K + + + A+ A
Sbjct: 190 ARRLARGTIYGAGRMLDDLPDSAEDLRKAVTSPNGTTAAALAVLMKSDAWPETVPKAIDA 249
Query: 881 AVDR 892
A R
Sbjct: 250 ATKR 253
>UniRef50_A7LUS1 Cluster: Putative uncharacterized protein; n=1;
Bacteroides ovatus ATCC 8483|Rep: Putative
uncharacterized protein - Bacteroides ovatus ATCC 8483
Length = 271
Score = 87.0 bits (206), Expect = 9e-16
Identities = 49/173 (28%), Positives = 91/173 (52%), Gaps = 2/173 (1%)
Frame = +2
Query: 371 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAF-SRGTKATAEDAQL 547
++ ++ +S+ G+ I+ + +E + R +PN + SRGT E QL
Sbjct: 85 SRTQILVSLVSGVCISHLAHLTEAEMPIFRAVPNMAITERSSLTLIASRGTDK--EYQQL 142
Query: 548 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 727
Q+F+ G C + E Q+D +AL+ SG A+ ++++ G+ G+P A+++AA
Sbjct: 143 IKQIFEEGGKCLFLQEKQLDTTSALTSSGIAFALKYMQAVMQAGIELGIPGKDAMQMAAY 202
Query: 728 TTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
+ G+ ++ HP + + VT+P G+T +G LE GF S+II A+ ++
Sbjct: 203 SMEGATELILNHNTHPLLEIEKVTTPGGTTIKGLNELEHKGFTSSIIQAIKSS 255
>UniRef50_Q88GE6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Pseudomonas putida KT2440|Rep: Pyrroline-5-carboxylate
reductase - Pseudomonas putida (strain KT2440)
Length = 264
Score = 85.8 bits (203), Expect = 2e-15
Identities = 57/170 (33%), Positives = 86/170 (50%), Gaps = 2/170 (1%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
+SV GIT AT+ L +A V+R +PNTP+ V +G + + A A Q+F
Sbjct: 90 VSVMAGITHATLVRLLGHDA-VVRAIPNTPSEVAQGVTMYYAPSDADAALIDSARQIFDV 148
Query: 569 VGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 745
+G V E Q+D TAL+G GPA V ++L D G+ GL + A +A Q G+A
Sbjct: 149 IGLSLRVNDERQIDTGTALAGGGPALVAHFADALQDYGLHMGLDSEQAAVVALQLLSGTA 208
Query: 746 AMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
A+++ PA + V + G+T L+ GF+ + A+ AA R
Sbjct: 209 ALIQASGKPASQICQEVQTAGGTTERAIRALDAAGFKGLVNAALDAAARR 258
>UniRef50_Q2NCY1 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Sphingomonadales|Rep: Pyrroline-5-carboxylate reductase
- Erythrobacter litoralis (strain HTCC2594)
Length = 269
Score = 85.8 bits (203), Expect = 2e-15
Identities = 55/155 (35%), Positives = 80/155 (51%), Gaps = 3/155 (1%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTP-ALVKEGAAAFSRGTKATAEDAQLTSQLFK 565
+SV GI +A++ + P V+R MPN AL K G T + + L +
Sbjct: 88 LSVLAGIELASLRARFPQAEGVVRFMPNLACALGKAPNGLIGEGLSDTQRG--MVTDLAE 145
Query: 566 AVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
+G+ + + E + D +TAL+GSGP +VY I++LA G R GL A RLA Q G+
Sbjct: 146 KLGSAEWLEDESRFDLVTALAGSGPGFVYRFIDALAVAGTRLGLDEGQAGRLAIQMVEGA 205
Query: 743 AAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKN 844
AA+ +H P L V SP G T +G L++N
Sbjct: 206 AALAAQSEHSPGELARRVASPGGMTQKGLDVLDEN 240
>UniRef50_Q1U6D2 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Lactobacillus reuteri|Rep: Pyrroline-5-carboxylate
reductase - Lactobacillus reuteri 100-23
Length = 270
Score = 85.4 bits (202), Expect = 3e-15
Identities = 55/176 (31%), Positives = 86/176 (48%), Gaps = 1/176 (0%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
+S+ G+T+A + S A + R++PNT + + A +S K + + +
Sbjct: 95 LSIIAGVTVAQLSSQEDLFA-ITRIIPNT---LTDVAMGYSGVVKNDRANQTVIEDFLNS 150
Query: 569 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 748
G D + E +D T +GP Y+Y + S + GV G+PR A +LA + +AA
Sbjct: 151 FGKVDYIDESLLDVFTGYGVAGPNYIYNFLISFTNAGVLAGMPRQQANKLALENLRAAAA 210
Query: 749 MV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
V ++G HPA L D S G + L+K+ F + I AV AAV R K + KQ
Sbjct: 211 FVEQSGKHPAELLDINNSAGGVGITAQHELDKSSFSAGIENAVLAAVKRTKELGKQ 266
>UniRef50_A3X4C4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Roseobacter sp. MED193|Rep: Pyrroline-5-carboxylate
reductase - Roseobacter sp. MED193
Length = 224
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/211 (31%), Positives = 97/211 (45%), Gaps = 2/211 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXX 292
KI F GGG + A+ G IS+G P IT +D A + + ++
Sbjct: 3 KIAFTGGGNMTAAIIGGLISSGW-DPSRITVVDPNADQRVRLAAEH--GVHITDDVATAA 59
Query: 293 XXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPN 472
++ KL +S+A G+TI T+E L + R MPN
Sbjct: 60 IADIIVLAVKPQVINAVAGQMTT--DLSGKLLLSIAAGVTIGTLEQ-LFGPVAIARTMPN 116
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQ-LFKAVGTCDEVP-EYQMDAITALSGSGPAYV 646
TPAL+ GA T+E +L +Q + ++ G C V E +D++TA+SGSGPAY
Sbjct: 117 TPALLSLGATGLYVNDH-TSEVQRLEAQKIIESFGICVAVAKEDLLDSVTAVSGSGPAYY 175
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
+++IE + G GL R+ A L QT LG
Sbjct: 176 FLMIEEMIKAGTAQGLSREDAAALTVQTALG 206
>UniRef50_A7AD19 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 268
Score = 85.0 bits (201), Expect = 4e-15
Identities = 66/268 (24%), Positives = 105/268 (39%), Gaps = 10/268 (3%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKI IG G + A+A G + K +IT + +N
Sbjct: 1 MKITIIGAGNIGGAIARGLAKGHMFKASDITCTAQSDTTLEKMRNTNPDFVLSLDNVEAV 60
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA------- 448
+ +IK + ++ +SVA GIT + + L
Sbjct: 61 KGADIIVIAVKPWRVEEIIDQIKGILDYDKQIIVSVAAGITFDLLNTYLTKNTGFDDCLT 120
Query: 449 --RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITAL 622
+ R+MPNT A+ + F A+ E L +F +G V E M A TAL
Sbjct: 121 TPTIFRIMPNT-AIEVLSSMTFVAARNASKEQTDLIINIFNELGNAMLVEERLMSAGTAL 179
Query: 623 SGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTS 799
+ SG A+ I + +GGV G A + T G+ +++ +P D VT+
Sbjct: 180 ASSGIAFALRYIRAAIEGGVELGFYPKQAQEIVVHTVKGAVDLLLENKSNPETEIDKVTT 239
Query: 800 PAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
P G T +G +E +GF S++I + A+
Sbjct: 240 PGGITIKGLNEMELSGFTSSVIRGLKAS 267
>UniRef50_A0RR69 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Campylobacter fetus subsp. fetus 82-40|Rep:
Pyrroline-5-carboxylate reductase - Campylobacter fetus
subsp. fetus (strain 82-40)
Length = 248
Score = 85.0 bits (201), Expect = 4e-15
Identities = 73/262 (27%), Positives = 124/262 (47%), Gaps = 1/262 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKI +GGG + A+A G ++G D I +A+ K G GA ++
Sbjct: 1 MKIYILGGGNMGTAMAYGLKNSGF---DVIIVCRDKEKLANFKKI-GFGAEIYGKSYDIK 56
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
AL + NL S + ++ ISV I + S++ ++ + +P
Sbjct: 57 DKNIILAVKPY------ALSSVSNLLSGEAEVCISVLARTGIEMLNSSIKAKNYAV-CLP 109
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYV 646
N A F + +D + ++ G C ++ + ++DA + L+G PAY+
Sbjct: 110 NIAAKFNSSVTPFI----SDGDDNTIV-EILNGFGKCVKLETKNELDAASVLAGCAPAYL 164
Query: 647 YMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGT 826
++ E+L++ GV GL +D A L G A ++K+ HPA++K++V SPAG+T EG
Sbjct: 165 ALVAEALSNAGVLEGLKKDDANFLVNGLFDGFAKLLKSS-HPALIKESVCSPAGTTIEGV 223
Query: 827 YHLEKNGFRSAIIGAVSAAVDR 892
LE+ G R A + AV A+ +
Sbjct: 224 AKLEECGVRHAFLQAVKASAKK 245
>UniRef50_Q4HSX5 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Campylobacter|Rep: Pyrroline-5-carboxylate reductase -
Campylobacter upsaliensis RM3195
Length = 244
Score = 84.6 bits (200), Expect = 5e-15
Identities = 56/179 (31%), Positives = 94/179 (52%), Gaps = 1/179 (0%)
Frame = +2
Query: 341 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 520
AL E+ + + ++ ISV ++ +E + R+MPN A K F
Sbjct: 67 ALNEMSQILKGEARILISVLANTSLKELECIRAQN--IARIMPNIAAKYKASTTPFILKN 124
Query: 521 KATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 697
+ E+ Q+ + G E+ E QM + ALSG PA++ ++ E+LA+GGV GL
Sbjct: 125 ELFKEEI---IQILTSFGNAYELSSEKQMPSAMALSGCAPAFLSLVAEALANGGVYRGLD 181
Query: 698 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 874
++L+L+L Q S + + +HPA++K++V SPAG + +G LE+ R+A + AV
Sbjct: 182 KELSLKL-TQGLFESFSTLLAHEHPALIKESVCSPAGVSIKGVKVLEERAIRAAFMEAV 239
>UniRef50_Q0P9H8 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Campylobacter|Rep: Pyrroline-5-carboxylate reductase -
Campylobacter jejuni
Length = 243
Score = 83.4 bits (197), Expect = 1e-14
Identities = 52/182 (28%), Positives = 98/182 (53%), Gaps = 1/182 (0%)
Frame = +2
Query: 341 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 520
AL+ I + + ++ ISV + +++ +R++PNT A K +
Sbjct: 65 ALENIAQMLKGQARILISVLANVDFEKLQTI--KAQNYVRIIPNTAAKYKASTTPYI--L 120
Query: 521 KATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 697
K + + ++ + K G+ ++ E QM+A A+SG PA++ ++ ES+A+ GV GL
Sbjct: 121 KNSHFENEILD-ILKTFGSAYKLDNEIQMNAAMAISGCAPAFLALIAESIANAGVYEGLS 179
Query: 698 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 877
++L+L L S A+++ +HPA++K+N+ SP G T +G LE+ G R + A++
Sbjct: 180 KELSLNLTRSLFKSSNALLE-HEHPAIIKENICSPGGVTIKGIKILEQKGIRGSFFEAIN 238
Query: 878 AA 883
A+
Sbjct: 239 AS 240
>UniRef50_Q54IL7 Cluster: Pyrroline-5-carboxylate reductase; n=3;
cellular organisms|Rep: Pyrroline-5-carboxylate
reductase - Dictyostelium discoideum AX4
Length = 551
Score = 83.4 bits (197), Expect = 1e-14
Identities = 66/271 (24%), Positives = 119/271 (43%), Gaps = 12/271 (4%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXXXX 295
+ +G G L A+A G +++ K ++I + ++++ + + G N
Sbjct: 8 VAVLGCGNLGNAIAKGLVASKQFKSNQIVLT--KRNLSTIEPLKREGYHVTTSNHDAVSR 65
Query: 296 XXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNT 475
L IK + +N + ISV G +I + S+L + ++R MPNT
Sbjct: 66 CKIVIVCVVPAQLDDLLDSIKQSVT-ENHIIISVVSGASIEDIRSHLEKDVPIVRAMPNT 124
Query: 476 PALVKEG------AAAFSRGTKATAEDA-----QLTSQLFKAVGTCDEVPEYQMDAITAL 622
+ ++ + T + ++ A ++ ++F +G + E Q+ TAL
Sbjct: 125 AIQHCQSMTCLAIRSSHQKSTNSPSDKAKDNALEVAKKIFNCLGMSIVLSEEQIVPATAL 184
Query: 623 SGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA-MVKTGDHPAMLKDNVTS 799
G A+ I + A GG G + A+R+AAQT G+A +++ HP D VT+
Sbjct: 185 CACGIAFFCRAIRAAAQGGCEIGFHAEDAIRIAAQTAKGAATLLLENNFHPEYEIDKVTT 244
Query: 800 PAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 892
P G T G +E GF SA+I + + D+
Sbjct: 245 PQGCTIAGLNQMEHAGFSSAMIKGIVTSSDK 275
>UniRef50_Q1NBI0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sphingomonas sp. SKA58|Rep: Pyrroline-5-carboxylate
reductase - Sphingomonas sp. SKA58
Length = 270
Score = 82.6 bits (195), Expect = 2e-14
Identities = 44/147 (29%), Positives = 72/147 (48%), Gaps = 2/147 (1%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
+S+ G T+ + + P+ ++R MPN P + +G A + L
Sbjct: 92 LSILAGTTLGDLRARFPATGDIVRAMPNLPVGMGQGVVALYTDAHTSPSGRANMEALLGP 151
Query: 569 VGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 745
+G + + + + + +TALSG GPA+++ +++L+ G G+P D A R+A T G+A
Sbjct: 152 LGLSEWMADEALFNRVTALSGCGPAFLFRFVDALSRAGEAIGIPADQAARMAMATVQGAA 211
Query: 746 AMVKTGD-HPAMLKDNVTSPAGSTAEG 823
M PA L D V SP G T EG
Sbjct: 212 NMAAAAQVTPATLADQVASPGGMTREG 238
>UniRef50_A3VSN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Parvularcula bermudensis HTCC2503|Rep:
Pyrroline-5-carboxylate reductase - Parvularcula
bermudensis HTCC2503
Length = 273
Score = 82.6 bits (195), Expect = 2e-14
Identities = 74/265 (27%), Positives = 111/265 (41%), Gaps = 7/265 (2%)
Frame = +2
Query: 125 IGGGRLAFALANGFISAGLAKPDEITASC-HPSDVASAKAFQGLGATALFENXXXXXXXX 301
+G G + AL ++ G+ P S +PSD A A + G E+
Sbjct: 10 VGAGNMGGALFTSWVEKGVLDPARSAISDPNPSDAVIALA-EKAGIAINPEDDQPYEVCV 68
Query: 302 XXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA---RVIRVMPN 472
P L+ + LFIS+A G ++ + L +A R++R MPN
Sbjct: 69 LGIKPQLFGAVLPDLQ----FGGMNDALFISMAAGTSLGEIGKLLKGQAPNARLVRTMPN 124
Query: 473 TPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVY 649
PA + EG + G T +D + L +A G E +D +T +SGSGP +V
Sbjct: 125 LPAAIGEGMSLLCAGEGVTDKDKAAATALMEAAGQVVWTKTEDDVDRLTGVSGSGPGFVL 184
Query: 650 MLIESLADGGVRCGLPRDLALRLAAQTTLGSAA-MVKTGDHPAMLKDNVTSPAGSTAEG- 823
++E+ G A LA QT +G+A + + G A L+ VTSP G+T G
Sbjct: 185 YVVEAFEAAAKAQGASDSDARLLAEQTIIGTALHLSRDGRTAAELRKAVTSPGGTTEAGL 244
Query: 824 TYHLEKNGFRSAIIGAVSAAVDRCK 898
+ I AV AA DR +
Sbjct: 245 NVLMADERLHRLIAEAVEAAYDRAQ 269
>UniRef50_Q4WFG1 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Trichocomaceae|Rep: Pyrroline-5-carboxylate reductase -
Aspergillus fumigatus (Sartorya fumigata)
Length = 280
Score = 82.6 bits (195), Expect = 2e-14
Identities = 46/152 (30%), Positives = 78/152 (51%)
Frame = +2
Query: 419 TVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEY 598
T + S+A ++R MPN A +++ + + A + +F+ +G +
Sbjct: 118 TPADDAESKAIIVRAMPNVAARLRQSMTIIEINNNLSHDIADTLTWIFEQIGKVKFLAAD 177
Query: 599 QMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAM 778
D T L GS A + + + + DG V GL R AL +AAQ +G A +++ G HPA+
Sbjct: 178 LFDIGTMLVGSSIAVLTVPFDGILDGCVAEGLRRADALEMAAQNLIGMAGLLREGVHPAI 237
Query: 779 LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 874
L+++++SP G T +G +EK G R A A+
Sbjct: 238 LRESISSPRGCTIQGLLAVEKEGMRGACAQAM 269
>UniRef50_UPI000050FC3D Cluster: COG0345: Pyrroline-5-carboxylate
reductase; n=1; Brevibacterium linens BL2|Rep: COG0345:
Pyrroline-5-carboxylate reductase - Brevibacterium
linens BL2
Length = 278
Score = 81.0 bits (191), Expect = 6e-14
Identities = 46/179 (25%), Positives = 85/179 (47%)
Frame = +2
Query: 377 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 556
+ + +S+A G+ +A + + P ++R+MPNTP+ + G A + +
Sbjct: 94 DSVLVSMAAGVAMADLATLAPQNP-IVRIMPNTPSSIGHGVIALAPSAEVDDTIVDTLRT 152
Query: 557 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 736
L G + E ++ A+T +SGSG AY ++L E++ GV+ GL + A ++ T
Sbjct: 153 LLSGAGLVVALDESEIPAMTGISGSGVAYFFLLAETMIAAGVKMGLSEETAKQMVVATAD 212
Query: 737 GSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 913
G+ ++ P+ + V+S G+T G G AV AA +R ++K+
Sbjct: 213 GAGRLLTEKPDPSAQRQAVSSKGGTTLAGLQTFIDAGLFDTTEAAVQAAGNRSLEMEKE 271
>UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=1;
Mesoplasma florum|Rep: 1-pyrroline-5-carboxylate
reductase - Mesoplasma florum (Acholeplasma florum)
Length = 266
Score = 79.8 bits (188), Expect = 1e-13
Identities = 50/188 (26%), Positives = 90/188 (47%), Gaps = 3/188 (1%)
Frame = +2
Query: 338 PALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARV--IRVMPNTPALVKEGAAAFS 511
P K + L + K I +A +TI V++N +V IR+MPN A +++ A +
Sbjct: 78 PLCKNMDQL-NIDGKTIICMANAVTIEDVQNNFVKNKKVSVIRMMPNMNASIQKSVTALA 136
Query: 512 RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 691
A+ E + S++F+ G + + E + +TA+SG P+Y+ +++ D + G
Sbjct: 137 T-KNASNETMKFVSEMFELCGIVENIDEDKFGTLTAISGCSPSYIISFFKAMTDYAIDKG 195
Query: 692 LPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 868
++ A R+ + +GS K+ + D + P GST EG L+ F I
Sbjct: 196 FEKEQAFRIIEEAIIGSVMNASKSEVELRTMVDQICVPNGSTIEGQKILDNKNFEKIIQE 255
Query: 869 AVSAAVDR 892
A++AA +
Sbjct: 256 ALTAATKK 263
>UniRef50_Q1M3U8 Cluster: Putative pyrroline-5-carboxylate
reductase; n=2; Rhizobium|Rep: Putative
pyrroline-5-carboxylate reductase - Rhizobium
leguminosarum bv. viciae (strain 3841)
Length = 264
Score = 78.6 bits (185), Expect = 3e-13
Identities = 54/173 (31%), Positives = 84/173 (48%), Gaps = 2/173 (1%)
Frame = +2
Query: 371 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 550
A KL ISV GI + + S + RVIR +PN A V + + T +D L
Sbjct: 82 AGGKLIISVMAGIRLDAL-SERHNTGRVIRALPNAAAEVAKSYTPWIGARDVTEDDRALV 140
Query: 551 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 727
+F+A G+ DEV E +D +T LSGSGPA+ +L ++ V GLP ++A R
Sbjct: 141 RAIFQACGSEDEVARESDIDYLTGLSGSGPAFPALLAAAMMRDAVANGLPAEIARRAVNT 200
Query: 728 TTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
G+ +++ D P + + G+TA + GF +++ +SAA
Sbjct: 201 VITGAGRLLERHDECPDDVVETFVGYRGTTAAAIEGMRVAGFDASVAKGLSAA 253
>UniRef50_A3CV24 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Methanoculleus marisnigri JR1|Rep:
Pyrroline-5-carboxylate reductase - Methanoculleus
marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length = 266
Score = 78.6 bits (185), Expect = 3e-13
Identities = 74/270 (27%), Positives = 113/270 (41%), Gaps = 5/270 (1%)
Frame = +2
Query: 116 IGFIGGGRLAFALANGFISAGLAKPDE--ITASCHPSDVASAKAFQGLGATALFENXXXX 289
IG IG G + L +GF+S+G+ DE +T+ S A A A+ G+G A N
Sbjct: 4 IGVIGYGHMGSMLVDGFLSSGVLGVDEVVVTSRRQESRDACAAAWPGIGIAA--TNSELA 61
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAK-NKLFISVAMGITIATVESNLPSEARVIRVM 466
L EI P+ ++ +S+A G+ + +E V R +
Sbjct: 62 RQCRTIILAVRPQEVKDVLHEI--FPAMDGDEHIVSLAAGVGLTELEGLF--SGSVTRAI 117
Query: 467 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYV 646
P + + +G G + DA LF ++G V E ++ A T LS GP +
Sbjct: 118 PTITSTIGQGTTLVCHGRQVGMHDALRIEGLFSSIGNVMLVGEEELPAATILSSCGPGLL 177
Query: 647 YMLIESLADGGVRC-GLPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAE 820
+IE LA L D AL LA +T +AA ++ TG+ P L V + G T
Sbjct: 178 AAVIEELAGAAAHASSLSGDRALELATETAAATAAYLRETGETPGDLVGRVATGGGVTEV 237
Query: 821 GTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
G + + AV+A ++R V K
Sbjct: 238 GVKGIRER-LPEVFDEAVAAMLERYGAVGK 266
>UniRef50_A0HA22 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Comamonas testosteroni KF-1|Rep:
NADP oxidoreductase, coenzyme F420-dependent - Comamonas
testosteroni KF-1
Length = 268
Score = 77.4 bits (182), Expect = 7e-13
Identities = 50/189 (26%), Positives = 91/189 (48%), Gaps = 7/189 (3%)
Frame = +2
Query: 368 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED--A 541
S K + +S+ GI++ T+++ P +R+IR++PNTP G + + A
Sbjct: 80 SHKVDIVVSMMAGISVDTIKTVFPG-SRIIRIIPNTPCAFGAGITPIYTDFNSLKDTTTA 138
Query: 542 QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 721
+ + L + + E ++ T +S GPAY+ ++ E++ G + +L
Sbjct: 139 SVLTALSRLGPLMPVLDEPMINCATGISAGGPAYIMLIAEAMISTAEEMGFEPAESRQLV 198
Query: 722 AQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEK----NGFRSAIIGAVSAAV 886
A T LGSA +++T P L V +P G+T G L++ N FR+A++ A A+
Sbjct: 199 AHTLLGSAELLIQTSKSPRELAQEVMTPNGTTERGVSELQRRDIGNSFRTALLNASKRAI 258
Query: 887 DRCKIVKKQ 913
D + + Q
Sbjct: 259 DIARESRNQ 267
>UniRef50_A3M414 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Acinetobacter baumannii ATCC 17978|Rep:
Pyrroline-5-carboxylate reductase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 182
Score = 76.6 bits (180), Expect = 1e-12
Identities = 55/174 (31%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +2
Query: 404 GITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TC 580
G+ I + S + ++IRV+ N P L G D ++ ++ A G T
Sbjct: 4 GVNIQQLMS-ITGSKKIIRVISNPPVLTYTGTHVLIGSDYLEPLDKEVIETIYSATGRTY 62
Query: 581 DEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-K 757
E Q DAI ALSGSGPAY + +++S+ GV GL + AL L Q G+ MV K
Sbjct: 63 WANSESQSDAIIALSGSGPAYFFYILDSMVKTGVSMGLDKQFALDLILQAASGAVEMVRK 122
Query: 758 TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLN 919
+ P+ L VT G T E I A+ AA R K + ++N
Sbjct: 123 SNVQPSELCGKVTLANGITESALRMFELGNLSDDIRLALKAAYHRSKEISLEIN 176
>UniRef50_Q0AL89 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Alphaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Maricaulis maris (strain MCS10)
Length = 259
Score = 76.2 bits (179), Expect = 2e-12
Identities = 50/172 (29%), Positives = 83/172 (48%), Gaps = 3/172 (1%)
Frame = +2
Query: 386 FISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFK 565
++S+A G + A++ L + VIR+MPN PAL+ + L ++L +
Sbjct: 84 YVSIAAGFSTASL-GKLVGDQPVIRIMPNLPALIGRSVNGLFANPTCQDKHRDLANELAR 142
Query: 566 AVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
GT + E ++D +TA++GSGP YV+ + S G ++ A L +T G+
Sbjct: 143 TTGTAVWLDDEDELDRLTAIAGSGPGYVFEIARSYVAAAQALGFSKETARALVLETMGGA 202
Query: 743 AAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAAVDR 892
M D A L+++V S G+T G L ++G A++ AA DR
Sbjct: 203 IEMATRSDQDVADLRNSVMSKNGTTEAGINVLRRDGQLDALLRDTTRAAYDR 254
>UniRef50_A1B1A3 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Paracoccus denitrificans
PD1222|Rep: NADP oxidoreductase, coenzyme F420-dependent
- Paracoccus denitrificans (strain Pd 1222)
Length = 262
Score = 76.2 bits (179), Expect = 2e-12
Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 3/157 (1%)
Frame = +2
Query: 449 RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALS 625
R++RVMPN A + + F T D +L A+GT DE+ E Q+D +TAL
Sbjct: 104 RIVRVMPNAAAEIGGSYSPFWVAEGVTDADRDTVRRLLSAIGTTDELETEAQIDLMTALP 163
Query: 626 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV--KTGDHPAMLKDNVTS 799
GSG AY ++ ++A G+ +A R A +G A ++ + + PAM+
Sbjct: 164 GSGAAYPALMAVAMAGFMQAQGVSEPIAWRAAEAAVIGGARLLEGRISEAPAMVA-AYRD 222
Query: 800 PAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 910
G+TA G E GF A++ A+ AA D+ + + K
Sbjct: 223 YRGTTAAGLEAAEAAGFSRAVVAALEAATDKARRMAK 259
>UniRef50_A6DA85 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Caminibacter mediatlanticus TB-2|Rep: Delta
1-pyrroline-5-carboxylate reductase - Caminibacter
mediatlanticus TB-2
Length = 247
Score = 75.8 bits (178), Expect = 2e-12
Identities = 53/189 (28%), Positives = 93/189 (49%), Gaps = 4/189 (2%)
Frame = +2
Query: 344 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 523
L+E+ + K+ IS+ G ++ +E + S +R MPN AA + T
Sbjct: 68 LQEVSMRIKGEAKVLISILAGKSVFEIEKYIKSNY-YLRAMPNI-------AAKYQASTT 119
Query: 524 ATAEDAQLTSQLFKAVGTCDEV----PEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 691
A D ++ K +G +V + ++D TA+ GSGPA++ ++ ++ D GV G
Sbjct: 120 ALTGDVEVKELGEKILGYIGDVIWVNNDDEIDMATAIIGSGPAFLSLIASAIEDAGVYTG 179
Query: 692 LPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGA 871
L R+++ +L ++ + D +K+ V SP G+TAEG Y LE++G R I+
Sbjct: 180 LKREISHKLTKGLFKSFTSLKENFD---TIKNQVMSPKGTTAEGVYSLEEDGIRGKIMKG 236
Query: 872 VSAAVDRCK 898
V ++ K
Sbjct: 237 VIKTYEKSK 245
>UniRef50_Q67T73 Cluster: ComE operon protein 4; n=1;
Symbiobacterium thermophilum|Rep: ComE operon protein 4
- Symbiobacterium thermophilum
Length = 270
Score = 74.9 bits (176), Expect = 4e-12
Identities = 66/272 (24%), Positives = 114/272 (41%), Gaps = 7/272 (2%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
M IGFIG G + L + AG +PDE+ + G +
Sbjct: 1 MAIGFIGMGNMGRLLVTALVRAGALQPDEVLIYSRSPEKRRRVTAALPGVQEAYGGGDLA 60
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L+EI +A + L +++ +T+A +E+ P AR +V+P
Sbjct: 61 RRAGVVFLCVKPPETAGVLEEIGPYITADH-LLVTINNTVTLAMLEARTP--ARAAKVIP 117
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
+ V+ G + G + T D L +L AV VPE + + L+ GPA++
Sbjct: 118 SVVHAVRRGVSLLVFGGRCTHRDRALLMRLMGAVSRPFVVPEEAVRTASDLTACGPAFLS 177
Query: 650 MLIESLADG--GVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAE 820
+++ ++A+ G L R+ + + +T + M +TG A + V +P G A
Sbjct: 178 LVLHAMAEAARGKAPALSREAVMAMVRETARATCELMEQTGYDFADVAARVATPGGVAAA 237
Query: 821 G--TYHLEKNGFRSAIIGAVSA--AVDRCKIV 904
G H +GF A++ A +A A R ++V
Sbjct: 238 GVDALHPRLDGFWEAVLAATAAHEAAKRAQLV 269
>UniRef50_Q7VHX1 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Helicobacter hepaticus|Rep: Pyrroline-5-carboxylate
reductase - Helicobacter hepaticus
Length = 284
Score = 74.5 bits (175), Expect = 5e-12
Identities = 54/174 (31%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
Frame = +2
Query: 392 SVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ----L 559
SV G +IA ++ +L S + ++R+MPN A K A AF T + AQ+
Sbjct: 98 SVLAGTSIAMIQKHL-SASSIVRLMPNIAAHSKLSATAFYYHMLDTKDSAQVLHNEIRPF 156
Query: 560 FKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 736
++ G +V E +++ A SGS A++ ++ ESL D G+ GL ++ L QT +
Sbjct: 157 IESFGVAVQVDSEALIESSIAASGSSIAFLALIAESLIDAGILEGLNEQQSIALVKQTFV 216
Query: 737 GSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
G A + P LK ++SP G+T G LE++G R +I A A + +
Sbjct: 217 GFATEL-AHKSPNELKYAISSPGGTTIRGLAVLEESGMRGILIKAAHTAAEHAR 269
>UniRef50_Q5FK14 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Lactobacillus acidophilus
Length = 91
Score = 73.7 bits (173), Expect = 9e-12
Identities = 40/83 (48%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = +2
Query: 620 LSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVT 796
+SG GPA+V + +++L D GV GL RD A LAA GSA + +T PA+L+D V
Sbjct: 4 ISGYGPAFVDIFLDALGDAGVLNGLSRDQANTLAANMVKGSANLAYETKIAPAILRDQVC 63
Query: 797 SPAGSTAEGTYHLEKNGFRSAII 865
SP G+T +G LEK+GFR II
Sbjct: 64 SPGGTTIQGVASLEKHGFRYTII 86
>UniRef50_Q6MQK1 Cluster: ProC protein; n=1; Bdellovibrio
bacteriovorus|Rep: ProC protein - Bdellovibrio
bacteriovorus
Length = 275
Score = 72.5 bits (170), Expect = 2e-11
Identities = 66/276 (23%), Positives = 118/276 (42%), Gaps = 2/276 (0%)
Frame = +2
Query: 95 PLIEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFE 274
PL+++ KIGF+G G +A A+ G I G P + + + S+ K + +F
Sbjct: 3 PLLKSQKIGFLGAGNMAQAMIKGLIEGGF--PAKNIFASNRSEGKLHKLAETFKINPVFS 60
Query: 275 NXXXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARV 454
N AL+ + ++K+ ISVA GI + +E + AR+
Sbjct: 61 NDELVDTCDIIILAIKPQDLLQALEPVTR-SFDEHKIVISVAAGIRMEKLERYVQG-ARL 118
Query: 455 IRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGS 631
RVMPNTP+L+ G + + LF+ +G +V E Q +A+ S
Sbjct: 119 ARVMPNTPSLIGRGVIGYLLNDDDDSGLDSTVEDLFQPLGRVIQVHDEDQFEALMVSCSS 178
Query: 632 GPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAG 808
G +V+ ++ D G + A + +T +G++ + + + L+ VTS G
Sbjct: 179 GTGFVFEMMMYWQDWIEEHGFSVEEARMMTIETFVGASLLAAQAREGVEDLQARVTSKKG 238
Query: 809 STAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 916
TA G + + A+ + A R K + +++
Sbjct: 239 VTAAGLQSMRELEIERALRISFEKAAMRNKEMAREI 274
>UniRef50_A3Y9M8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Marinomonas sp. MED121|Rep: Pyrroline-5-carboxylate
reductase - Marinomonas sp. MED121
Length = 261
Score = 70.9 bits (166), Expect = 6e-11
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 5/172 (2%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L +S+ G++ A ++ P ++V+R MPNTP G ++ + S
Sbjct: 77 LIVSMLAGVSCAEIQHYFP-HSQVVRCMPNTPCEFGVGITPIYFSGNSSGTFSAHYSAFL 135
Query: 563 KAVGTCDEV----PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 730
+A E+ E +D T +SG GPAYV ++ +++ G + + RL +T
Sbjct: 136 EAAQFMGELFFVEKESDIDGATGISGGGPAYVMLMADAMIKASQTLGFSYEESKRLVGKT 195
Query: 731 TLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 883
GS M++ D PA L +V +P G+T +G L+ +AI A+ A
Sbjct: 196 LEGSGKMLQMSDKMPAQLAQDVMTPNGTTEQGVNELKAKQVETAIYDALLKA 247
>UniRef50_A3K0L9 Cluster: Putative pyrroline-5-carboxylate reductase
protein; n=1; Sagittula stellata E-37|Rep: Putative
pyrroline-5-carboxylate reductase protein - Sagittula
stellata E-37
Length = 255
Score = 70.9 bits (166), Expect = 6e-11
Identities = 54/180 (30%), Positives = 85/180 (47%), Gaps = 3/180 (1%)
Frame = +2
Query: 368 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAE-DAQ 544
+A + L +SV G T A ++ S RVIR M ++PA + A G+ A E D
Sbjct: 75 AAPDALVLSVIAGATRARLQETTGSP-RVIRAM-SSPAAARRLAYTPWIGSAAITEADRT 132
Query: 545 LTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 721
+ +F A+G DE+ E +D TAL+G P + + ++A V G+P D+A R
Sbjct: 133 QANAVFSAIGRTDEIGDEAHIDLFTALTGPVPGFAALFASAMARHAVSQGVPPDIADRAV 192
Query: 722 AQTTLGSAAMVKTGDHPAMLK-DNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
Q L + M+ H A + + + AG+TA G + G + + AA DR +
Sbjct: 193 RQLFLSAGEMLAHDAHTADAHVEGMIAYAGTTAAGFLSMRAAGLEEIVANGLQAATDRAR 252
>UniRef50_A5EV67 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Dichelobacter nodosus VCS1703A|Rep:
Pyrroline-5-carboxylate reductase - Dichelobacter
nodosus (strain VCS1703A)
Length = 285
Score = 70.5 bits (165), Expect = 8e-11
Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
+ I++A GI I L E ++R MPN A V+ + D L +F
Sbjct: 95 VIITLAAGIKIEDYRKILGDEVTIVRAMPNIAASVQAALTGIYSDDGLSEHDENLIEDIF 154
Query: 563 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
A+G+ + E Q+D ITALSGSG AY Y L++++A G + G + + T LG
Sbjct: 155 SAIGSTAWLDDEIQLDGITALSGSGIAYFYRLMQAMAQAGEQYGFEKQELYDIITLTALG 214
Query: 740 SAAM 751
+A +
Sbjct: 215 AATL 218
>UniRef50_Q41BC1 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Exiguobacterium sibiricum 255-15|Rep:
Pyrroline-5-carboxylate reductase - Exiguobacterium
sibiricum 255-15
Length = 256
Score = 69.3 bits (162), Expect = 2e-10
Identities = 51/179 (28%), Positives = 81/179 (45%), Gaps = 2/179 (1%)
Frame = +2
Query: 344 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 523
L IK ++L +SVA IT A +E+++ A + MPNTP + G G
Sbjct: 73 LDYIKQQTWRTDQLVVSVAAHITPAEIEAHISCGA--VCAMPNTPVAFRTGMTGLWFGDL 130
Query: 524 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 703
+ E Q + LF VG E M + A +G PA+ Y ++ ++ + G
Sbjct: 131 VSDEKRQQATALFGRVGETVETNAATMPYLMAAAGCSPAFFYEIVGAMTPVLTKAGFDAS 190
Query: 704 LALRLAAQTTLGSAAMVKTGDHPA--MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 874
A R+ AQ GSA ++ + P ++KD V +P G T G L ++ A+ A+
Sbjct: 191 SARRIIAQAMKGSAELLLHEERPTEELIKD-VAAPGGPTDRGVRVLREHDLAQAMYEAL 248
>UniRef50_Q0G398 Cluster: Putative pyrroline-5-carboxylate reductase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
pyrroline-5-carboxylate reductase protein - Fulvimarina
pelagi HTCC2506
Length = 266
Score = 68.5 bits (160), Expect = 3e-10
Identities = 46/177 (25%), Positives = 80/177 (45%), Gaps = 2/177 (1%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
+ +S G+ +A +E N P +AR++R MP A D L +L
Sbjct: 87 IVVSFMAGVPLAHLERNWP-DARIVRAMPGGGAREGNAHVPICAADGIADADLDLVERLL 145
Query: 563 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
+GT D V E+++ +TALSGSG AY ++ +++ D GV G+ ++ R
Sbjct: 146 SVIGTVDRVANEHELAFLTALSGSGAAYPALMAKAMYDRGVAEGITPEVVWRAVTSVVCD 205
Query: 740 SAAMVKTGDHPAM-LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 907
+ ++++ A + + + G TA G G AI A+ AA R + ++
Sbjct: 206 APSLLRGSPAEASHMLETLEGYRGPTAAGIEAARLAGLGKAIGSALDAATKRAETMR 262
>UniRef50_A2A043 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteroidetes|Rep: Pyrroline-5-carboxylate reductase -
Microscilla marina ATCC 23134
Length = 266
Score = 68.1 bits (159), Expect = 4e-10
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L IS+ GI+I ++ +P+ ++IR MPN PA + G F+ ++ + L
Sbjct: 90 LLISIMAGISIDKIKRWVPT-TKIIRAMPNLPAQIGMGMTGFTAAASVDKKELFIVQNLI 148
Query: 563 KAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
G + E +++A+TA+SGSGPAYV+ ++++ D + G + A L QT +G
Sbjct: 149 NTTGKSLYFEDEEKLNAVTAISGSGPAYVFYFMQAMMDTAQQMGFSQSEAELLVEQTFMG 208
Query: 740 S 742
+
Sbjct: 209 A 209
>UniRef50_A3SP40 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Roseovarius nubinhibens ISM|Rep: Pyrroline-5-carboxylate
reductase - Roseovarius nubinhibens ISM
Length = 264
Score = 67.7 bits (158), Expect = 6e-10
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 2/174 (1%)
Frame = +2
Query: 383 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 562
L +SV G+++A + + A V+R MPN + + + + +A D + +
Sbjct: 89 LVLSVMAGVSMAEIRERTGARA-VVRSMPNAAMEIGQSFSPWVAEAEADDADRAMVRAVL 147
Query: 563 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 739
A G + E +D A+ G+GPA+ +L+E+LA G GL + AL A +G
Sbjct: 148 GASGREEAFAREADIDVYAAICGAGPAWAALLLEALAAAGRAEGLSPEQALAAAEGAVVG 207
Query: 740 SAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 898
+ AM+ G + D + AG+TA G GF A+ ++A + +
Sbjct: 208 AGAMLAGQGAQAGAMVDEFIAYAGTTAAGLEAARAAGFAEAVAAGIAAGTQKAR 261
>UniRef50_Q83FH8 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Tropheryma whipplei|Rep: Pyrroline-5-carboxylate
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 296
Score = 66.9 bits (156), Expect = 1e-09
Identities = 31/127 (24%), Positives = 61/127 (48%)
Frame = +2
Query: 374 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 553
+ KL +S+A + ++ + + LPS ++R N P V+ G S D +
Sbjct: 114 RKKLIVSLAKDVNLSNLAAMLPSGTAIVRCATNLPITVRHGFTGLSCNKHVLPSDVKAVY 173
Query: 554 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 733
LF+ +G C + E + ++A++G P Y+ ++ + + + GLPRD++
Sbjct: 174 TLFELLGRCTMLSEEHLTIVSAITGFYPVYMLYMLTKIKEATEKLGLPRDISQAAVETAW 233
Query: 734 LGSAAMV 754
+G A +V
Sbjct: 234 IGYAQVV 240
>UniRef50_A3UDP5 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Oceanicaulis alexandrii HTCC2633|Rep: Delta
1-pyrroline-5-carboxylate reductase - Oceanicaulis
alexandrii HTCC2633
Length = 251
Score = 66.9 bits (156), Expect = 1e-09
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 4/172 (2%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
+S+A G + A V S +R+MPN PA V G + +AT + +L + L +A
Sbjct: 76 VSIAAGASAAKV-SEAAGGVSALRLMPNMPARVGRGVSGLYADDRATKDHRELGTTLGEA 134
Query: 569 VGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGL-PRDLALRLAAQTTLGS 742
VG + E Q+D ITA +GSGP YV+ + G P+D A RL +T G
Sbjct: 135 VGEAIWLEDEDQIDRITAAAGSGPGYVFEFARTYQKAVEAQGFDPKD-ARRLVIETLAGC 193
Query: 743 AAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNG-FRSAIIGAVSAAVDR 892
A+ + L++++ S G+TA G L +G + A+ AA R
Sbjct: 194 MALALEDEAGFEDLRNSIMSKGGTTAAGVNALNGDGVLDERLNAALDAAYSR 245
>UniRef50_Q5FGR8 Cluster: Pyrroline-5-carboxylate reductase; n=6;
canis group|Rep: Pyrroline-5-carboxylate reductase -
Ehrlichia ruminantium (strain Gardel)
Length = 303
Score = 63.3 bits (147), Expect = 1e-08
Identities = 43/149 (28%), Positives = 79/149 (53%), Gaps = 2/149 (1%)
Frame = +2
Query: 374 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 553
K+ FIS+ GI I ++ +L S +IRVMPN + E + + + ++ Q
Sbjct: 118 KSASFISLCAGIDIEFLKKHLDSTT-IIRVMPNIAMSLGE-SVNLAYMEEEIDQEKQKVH 175
Query: 554 QLFKAVGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 730
+F G + + + D ++ ++GSGPAY + L E L ++ G+ + A++L +QT
Sbjct: 176 TVFNGTGLLYWLQKEDVFDKLSPITGSGPAYFFSLAEELVKNTMKAGIREEDAIKLISQT 235
Query: 731 TLGSAAMVKTGDHP-AMLKDNVTSPAGST 814
+GSA +++T + + L ++TS G T
Sbjct: 236 FIGSAKLLETRKNSISNLISSITSRGGIT 264
>UniRef50_Q4ML40 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus cereus G9241|Rep: Pyrroline-5-carboxylate
reductase - Bacillus cereus G9241
Length = 163
Score = 62.1 bits (144), Expect = 3e-08
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 1/162 (0%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITAS-CHPSDVASAKAFQGLGATALFENXXXX 289
+IGFIG G + A+ G ++ + + I S + +++ +A G+ T +N
Sbjct: 4 QIGFIGCGNMGMAIVGGMLNKHIVPSNHIICSDLNTTNLENASEKYGISITT--DNNEVA 61
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
+ EIK + + + +++A G +I + E+ + +V+RVMP
Sbjct: 62 KNADILILSIKPDLYPLVINEIKEVIK-NDAIIVTIAAGKSIESTENAFNKKLKVVRVMP 120
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPE 595
NTPALV EG +A T +D + +F + G + V E
Sbjct: 121 NTPALVGEGMSALCPNEMVTEKDLEDVLNIFNSFGQSEIVSE 162
>UniRef50_O25773 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Helicobacter|Rep: Pyrroline-5-carboxylate reductase -
Helicobacter pylori (Campylobacter pylori)
Length = 257
Score = 61.7 bits (143), Expect = 4e-08
Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 1/122 (0%)
Frame = +2
Query: 539 AQLTSQLFKAVGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 715
+Q + ++ G C V ++ DA A +GS A++ ++ SL D G+R GL +L
Sbjct: 137 SQKALSVIESFGNCVRVGHEELVDASVATNGSALAFLSLVANSLKDAGIREGLNARGSLE 196
Query: 716 LAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRC 895
L + G A +++ + P M+ + + +P G+T EG LEK G R A I A +V +
Sbjct: 197 LVKMSFKGFAKLLEK-ERPEMIIEQICTPKGATIEGLSVLEKKGVRGAFIEACHKSVKKM 255
Query: 896 KI 901
++
Sbjct: 256 RL 257
>UniRef50_Q59UW8 Cluster: Putative uncharacterized protein; n=2;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 213
Score = 60.5 bits (140), Expect = 9e-08
Identities = 55/171 (32%), Positives = 75/171 (43%), Gaps = 2/171 (1%)
Frame = -2
Query: 882 AADTAPI-MAERKPFFSK*YVPSAVDPAGLVTLSFNMAG*SPVL-TMAAEPRVVWXXXXX 709
AA + P+ +A P S P V P G+ TL FN AG SPV T+ A P +
Sbjct: 37 AASSTPLAIALLNPRSSMVNKPPIVVPPGVHTLLFNAAGCSPVSKTIRAVPSITLAAATD 96
Query: 708 XXXRGKPQRTPPSARDSISM*T*AGPLPLRAVIASIWYSGTSSQVPTALKSCDXXXXXXX 529
G P T PS DSI AGP P+ V S+++SG + +PT +
Sbjct: 97 ATSYGIPILTAPSIMDSIINKQKAGPDPINEVAMSMFFSGIFTVIPTVSINFITNSWLSS 156
Query: 528 XXXVPRLKAAAPSFTNAGVFGITRITRASEGKFDSTVAIVIPMATEMKSLF 376
AA P +AGV +T T K D++ IV+P E+ + F
Sbjct: 157 LTSGANAIAAVPQPNSAGVLVMTLATYGV--KIDNSF-IVVPANNEINNCF 204
>UniRef50_Q2FQL0 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Methanospirillum hungatei JF-1|Rep:
NADP oxidoreductase, coenzyme F420-dependent -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 227
Score = 56.8 bits (131), Expect = 1e-06
Identities = 35/126 (27%), Positives = 58/126 (46%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 568
+S+A I IAT+ + VIR++PN + V EG G+ + ++L A
Sbjct: 63 VSLAPKIKIATINQLTGASRSVIRMIPNAASYVNEGYNPVVFGSSCPENIRKKFTELMVA 122
Query: 569 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 748
+G EVPE ++A T ++ GP Y++ + L GL + A G+A
Sbjct: 123 LGQMPEVPEEMLEAYTVITAMGPTYLWFQLAELIHLAQTFGLTQKDATDAVLPMAEGAAK 182
Query: 749 MVKTGD 766
++K D
Sbjct: 183 IMKKSD 188
>UniRef50_A4R344 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 241
Score = 54.0 bits (124), Expect = 8e-06
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 362 LPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDA 541
L +A +++ G+++A + S LP V+R MPN P ++GA S A
Sbjct: 108 LRAAARPTVVTMCPGVSVAQLLSWLPRGTPVVRSMPNLPVTRRQGALFPS--ADAVGGSV 165
Query: 542 QLTSQLFKAVGTCDEV-PEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 715
+L + + V V PE + D ++SGS PAY Y LIESL G+ + A
Sbjct: 166 ELVAAVLGLVSPAVSVLPEESLLDVAASVSGSAPAYFYYLIESLVSAAEARGMSAETARS 225
Query: 716 L 718
L
Sbjct: 226 L 226
>UniRef50_UPI0000E45EAB Cluster: PREDICTED: similar to
pyrroline-5-carboxylate reductase-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyrroline-5-carboxylate reductase-like -
Strongylocentrotus purpuratus
Length = 120
Score = 53.6 bits (123), Expect = 1e-05
Identities = 43/140 (30%), Positives = 63/140 (45%)
Frame = +2
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 643
MPN V EG + RG AT ED + +L + + + + Q+D
Sbjct: 1 MPNVAIAVCEGNISGVRGAHATDEDMVVVGKLMNPISNYEVMSDPQLD------------ 48
Query: 644 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEG 823
++ S A GV G + ++TG HP +KD+V SP GST G
Sbjct: 49 ---IMSSTAGTGVAWGTGK---------------LYLETGKHPGEIKDSVCSPGGSTIRG 90
Query: 824 TYHLEKNGFRSAIIGAVSAA 883
+ LEK+G R+A++ AV AA
Sbjct: 91 VHALEKSGVRAAMMNAVEAA 110
>UniRef50_Q9KD86 Cluster: Non-essential gene for competence; n=2;
Bacillus|Rep: Non-essential gene for competence -
Bacillus halodurans
Length = 275
Score = 53.6 bits (123), Expect = 1e-05
Identities = 55/247 (22%), Positives = 97/247 (39%), Gaps = 2/247 (0%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MKIGFIG G + L F+ + ++I + + A A A + G + +
Sbjct: 1 MKIGFIGTGSMGTILIESFLESSALTAEQIVITNRTQEKADALARRYPGLSVVDRPEEVV 60
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
L +I+ SA NKL +S+ I+IA +E+++ + +V R +P
Sbjct: 61 QQTDCFFVCVKPMQFHRVLMDIRPHCSA-NKLLVSITSPISIAQLENSV--DCKVARAIP 117
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
+ G+ S + ED L + + E + + GPA+
Sbjct: 118 SILNRACAGSTLVSFSERCLEEDRSFLCGLLGTISEPLLIEEKITRVSSDIVSCGPAFFS 177
Query: 650 MLIESLADGGVR-CGLPRDLALRLAAQTTLGSAAMVKTGDHP-AMLKDNVTSPAGSTAEG 823
L + + VR + + A LA + +G ++ + L+ V P G T EG
Sbjct: 178 YLTQRFIEAAVRQTAISEEDATALATEMLIGIGKLLDQELYTLPSLQKRVCVPGGITGEG 237
Query: 824 TYHLEKN 844
LE++
Sbjct: 238 IRVLEED 244
>UniRef50_Q92BW8 Cluster: Lin1424 protein; n=12; Listeria|Rep:
Lin1424 protein - Listeria innocua
Length = 279
Score = 53.2 bits (122), Expect = 1e-05
Identities = 53/251 (21%), Positives = 102/251 (40%), Gaps = 3/251 (1%)
Frame = +2
Query: 113 KIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFEN-XXXX 289
KIGFIG G +A +A I + P+EI ++ + + T L N
Sbjct: 3 KIGFIGFGSMATLIATKLIETKVCTPEEIILYSSSANDHFKQFYDKYPTTELAANEAEVF 62
Query: 290 XXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMP 469
P +K+ + + +A ++ IS+A G++ + + PS +V +++P
Sbjct: 63 TKADHSFICKLPLAVLPLIKDCEAVLTA-DRHVISIAAGVSTSDILELSPS-LQVSKLIP 120
Query: 470 NTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVY 649
+ +V G S + ++ F+ G + E +D + L+ S P +
Sbjct: 121 SITTVVSVGTTLISHADTVSETNSAWLESAFENFGHVMTIREENIDIASDLTSSSPGIIA 180
Query: 650 MLIESLADGGVRCGLPRDLAL-RLAAQTTLGSAAMVKTGDHP-AMLKDNVTSPAGSTAEG 823
+ E + +R D + ++ G++ ++ D+ + L D V + G TAEG
Sbjct: 181 AIFEQFVEAALRRSTLSDAEIFQMINFALAGTSKLLVEEDYTFSGLIDRVATKGGITAEG 240
Query: 824 TYHLEKNGFRS 856
L K+ S
Sbjct: 241 V-ELSKSNLPS 250
>UniRef50_Q4FKY2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Candidatus Pelagibacter ubique|Rep: Delta
1-pyrroline-5-carboxylate reductase - Pelagibacter
ubique
Length = 255
Score = 53.2 bits (122), Expect = 1e-05
Identities = 62/256 (24%), Positives = 105/256 (41%), Gaps = 5/256 (1%)
Frame = +2
Query: 110 MKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENXXXX 289
MK+GFIG G++ A+ G S+ ++ ++I S +S + T +N
Sbjct: 1 MKLGFIGTGKITSAVITGICSSSISY-NKIIISERNKSTSSILKKKFKKITVSKDNQEII 59
Query: 290 XXXXXXXXXXXXXXXXPALKE--IKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRV 463
PA+ E IKNL N+ IS IT+A ++ + +A++IR
Sbjct: 60 NSCDWIFLSVT-----PAVGEKIIKNLKFRSNQTVISFISTITLAQLKKAIKVKAKIIRA 114
Query: 464 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSG-PA 640
+P P +K+G K + F +GT E+ + + +I S SG A
Sbjct: 115 IPLPPISLKKGPVPICPPNKKVKD-------FFNKIGTTVEI-KNEKSSINFWSTSGMMA 166
Query: 641 YVYMLIESLADGGVRCGLPRDLALRLAAQ--TTLGSAAMVKTGDHPAMLKDNVTSPAGST 814
Y L+ + D V+ G+ R+ A + L A+V + L +P G
Sbjct: 167 PFYELLRVMTDWLVKRGVKRNNAQKYITSLFLALSEDAVVNSKKDLKFLVKESQTPKGLN 226
Query: 815 AEGTYHLEKNGFRSAI 862
+G L + GF ++
Sbjct: 227 EQGVKELSRAGFYKSL 242
>UniRef50_A6RTE4 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 362
Score = 50.8 bits (116), Expect = 7e-05
Identities = 26/125 (20%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEG--AAAFSRGTKATAEDAQLTSQLF 562
++ A+GI+ +++ E ++R MP+ A E S T + ++ + +F
Sbjct: 139 MTAALGISESSIGKGKGKEIAIVRAMPSLAASFGESNTVVEISPSTALSQQNKSIVRYIF 198
Query: 563 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 742
+ +G+ EV Q DA + ++ + A++ + ++ + DGGV+ G+ R + ++ G
Sbjct: 199 RCIGSIVEVGPGQYDAASVMAATSMAFLTVALDGILDGGVKEGIKRSEGRDILVRSLKGL 258
Query: 743 AAMVK 757
+++
Sbjct: 259 VGLLE 263
>UniRef50_A1FCT9 Cluster: Pyrroline-5-carboxylate reductase-like;
n=1; Pseudomonas putida W619|Rep:
Pyrroline-5-carboxylate reductase-like - Pseudomonas
putida W619
Length = 121
Score = 50.4 bits (115), Expect = 9e-05
Identities = 28/58 (48%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +2
Query: 551 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 721
++LF+AVG+ V E +D +TALSGSGPAY + E+L+ GV GL +LA LA
Sbjct: 27 TRLFEAVGSTSWVEHEGLLDTVTALSGSGPAYYQLFSEALSAAGVALGLSPELARTLA 84
>UniRef50_UPI00015BAEC8 Cluster: pyrroline-5-carboxylate reductase;
n=1; Ignicoccus hospitalis KIN4/I|Rep:
pyrroline-5-carboxylate reductase - Ignicoccus
hospitalis KIN4/I
Length = 245
Score = 49.6 bits (113), Expect = 2e-04
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = +2
Query: 449 RVIRVMPNTPALVKEGAAAFS-RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALS 625
+V RVMP+ V + RG A + + ++ +G V E +DA +
Sbjct: 99 KVYRVMPSVTVEVNSSPVLVAERGGGADS----VVEAVWGKLGKVYWVNERVLDAALPVV 154
Query: 626 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPA 805
GSGPA S + V G+ R LA LA ++ +G+ M++ D P L+ V +P
Sbjct: 155 GSGPAVHAEYFRSAVEALVASGVERSLAEELARESIIGTIKMLEKYD-PYKLRSKVETPG 213
Query: 806 GSTAEGTYHLEKNG 847
G T E LE+ G
Sbjct: 214 GITVEMLLKLEEEG 227
>UniRef50_UPI0000DAE5EB Cluster: hypothetical protein
Rgryl_01000761; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000761 - Rickettsiella
grylli
Length = 138
Score = 43.2 bits (97), Expect = 0.014
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 1/136 (0%)
Frame = +2
Query: 101 IEAMKIGFIGGGRLAFALANGFISAGLAKPDEITASCHPSDVASAKAFQGLGATALFENX 280
++ + I FIG G +A ++ NG + + I A+ + S+ + L +N
Sbjct: 1 MQNLTISFIGAGNMATSIINGLLKKNFPAKN-IWATNNNSE--QLNQLKSLNINLTTDNK 57
Query: 281 XXXXXXXXXXXXXXXXXXXPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSE-ARVI 457
EI +N L IS+A+GI + +E+ L ++ +I
Sbjct: 58 TAVRRSTVVVLAVKPQILKSVALEIAKCMQERNPLVISIAVGIRLNHLENYLLNQNLALI 117
Query: 458 RVMPNTPALVKEGAAA 505
R MPNTPAL+ A A
Sbjct: 118 RCMPNTPALIGCAATA 133
>UniRef50_Q8ZW86 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Pyrobaculum|Rep: Pyrroline-5-carboxylate reductase -
Pyrobaculum aerophilum
Length = 238
Score = 39.9 bits (89), Expect = 0.13
Identities = 28/87 (32%), Positives = 39/87 (44%)
Frame = +2
Query: 587 VPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD 766
V E +D +T L GSGPA V L +L GV G+P DL+ R + + S +
Sbjct: 134 VEERLIDPLTVLLGSGPAIVAELALALIRAGVNIGIPWDLS-REIVLSLMASLPSLDDKF 192
Query: 767 HPAMLKDNVTSPAGSTAEGTYHLEKNG 847
L V +P G+T + L G
Sbjct: 193 SMEKLAQYVATPGGTTIKALVELSPAG 219
>UniRef50_Q8TGP2 Cluster: Uncharacterized protein YER023C-A; n=2;
Saccharomycetaceae|Rep: Uncharacterized protein
YER023C-A - Saccharomyces cerevisiae (Baker's yeast)
Length = 70
Score = 39.5 bits (88), Expect = 0.17
Identities = 21/45 (46%), Positives = 29/45 (64%)
Frame = -2
Query: 696 GKPQRTPPSARDSISM*T*AGPLPLRAVIASIWYSGTSSQVPTAL 562
G P P S +DS T AGP P +AV AS+++SG+S+ +PT L
Sbjct: 10 GIPNFNPLSIKDSNIKRTKAGPEPTKAVAASMFFSGSSTYLPTWL 54
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,002,231,621
Number of Sequences: 1657284
Number of extensions: 21456581
Number of successful extensions: 54490
Number of sequences better than 10.0: 261
Number of HSP's better than 10.0 without gapping: 51740
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54129
length of database: 575,637,011
effective HSP length: 102
effective length of database: 406,594,043
effective search space used: 123604589072
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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