Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP25_F_J12
(1207 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D13643-1|BAA02806.3| 553|Homo sapiens KIAA0018 protein protein. 248 3e-65
BC011669-1|AAH11669.1| 516|Homo sapiens 24-dehydrocholesterol r... 248 3e-65
BC004375-1|AAH04375.1| 516|Homo sapiens 24-dehydrocholesterol r... 248 3e-65
AF398342-1|AAL15644.1| 516|Homo sapiens 3beta-hydroxysterol del... 248 3e-65
AF261758-1|AAG17288.1| 516|Homo sapiens seladin-1 protein. 248 3e-65
AB073391-1|BAE45721.1| 427|Homo sapiens putative protein produc... 217 5e-56
BC036604-1|AAH36604.2| 521|Homo sapiens D-2-hydroxyglutarate de... 37 0.17
BC071598-1|AAH71598.1| 307|Homo sapiens D2HGDH protein protein. 34 0.90
>D13643-1|BAA02806.3| 553|Homo sapiens KIAA0018 protein protein.
Length = 553
Score = 248 bits (607), Expect = 3e-65
Identities = 123/282 (43%), Positives = 160/282 (56%)
Frame = +2
Query: 233 LWSIIRHSVVFKLXXAPKXHXXKVKXVQXQIKAWLSGDKSTHLCTARPTWQTMSFRHSMY 412
++ +R VVFKL AP+ H +V+ +Q Q++ W T +CT RP W T+S R Y
Sbjct: 85 IYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKY 144
Query: 413 KXTFTNIQINLVDVLEVDKENMTVRCEPLVTMGQLSRTXXXXXXXXXXXXXXDQLXXXXX 592
K T NI INL+D+LEVD + VR EPLVTMGQ++ D L
Sbjct: 145 KKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGL 204
Query: 593 XXXXXXXXXSHVHGLFQHVCLEYELVLADGSVVNCSKDENADLFYAVPWSYGTLGFLTSV 772
SH +GLFQH+C YELVLADGS V C+ EN+DLFYAVPWS GTLGFL +
Sbjct: 205 IMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAA 264
Query: 773 VIKVIPAKKYVRIHYYPFNNLSDLAKRFSQESLKPNPHQFVEALLYTXDSGVLMLGDMVD 952
I++IPAKKYV++ + P L + +F+ ES + H FVE LLY+ D V+M G M D
Sbjct: 265 EIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENH-FVEGLLYSLDEAVIMTGVMTD 323
Query: 953 EVGRXGKLNPIGVWHAEWFFKQVXXHXKXXARDKXYTS*KYY 1078
E KLN IG ++ WFFK V + K Y ++Y
Sbjct: 324 E-AEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHY 364
>BC011669-1|AAH11669.1| 516|Homo sapiens 24-dehydrocholesterol
reductase protein.
Length = 516
Score = 248 bits (607), Expect = 3e-65
Identities = 123/282 (43%), Positives = 160/282 (56%)
Frame = +2
Query: 233 LWSIIRHSVVFKLXXAPKXHXXKVKXVQXQIKAWLSGDKSTHLCTARPTWQTMSFRHSMY 412
++ +R VVFKL AP+ H +V+ +Q Q++ W T +CT RP W T+S R Y
Sbjct: 48 IYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKY 107
Query: 413 KXTFTNIQINLVDVLEVDKENMTVRCEPLVTMGQLSRTXXXXXXXXXXXXXXDQLXXXXX 592
K T NI INL+D+LEVD + VR EPLVTMGQ++ D L
Sbjct: 108 KKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGL 167
Query: 593 XXXXXXXXXSHVHGLFQHVCLEYELVLADGSVVNCSKDENADLFYAVPWSYGTLGFLTSV 772
SH +GLFQH+C YELVLADGS V C+ EN+DLFYAVPWS GTLGFL +
Sbjct: 168 IMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAA 227
Query: 773 VIKVIPAKKYVRIHYYPFNNLSDLAKRFSQESLKPNPHQFVEALLYTXDSGVLMLGDMVD 952
I++IPAKKYV++ + P L + +F+ ES + H FVE LLY+ D V+M G M D
Sbjct: 228 EIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENH-FVEGLLYSLDEAVIMTGVMTD 286
Query: 953 EVGRXGKLNPIGVWHAEWFFKQVXXHXKXXARDKXYTS*KYY 1078
E KLN IG ++ WFFK V + K Y ++Y
Sbjct: 287 E-AEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHY 327
>BC004375-1|AAH04375.1| 516|Homo sapiens 24-dehydrocholesterol
reductase protein.
Length = 516
Score = 248 bits (607), Expect = 3e-65
Identities = 123/282 (43%), Positives = 160/282 (56%)
Frame = +2
Query: 233 LWSIIRHSVVFKLXXAPKXHXXKVKXVQXQIKAWLSGDKSTHLCTARPTWQTMSFRHSMY 412
++ +R VVFKL AP+ H +V+ +Q Q++ W T +CT RP W T+S R Y
Sbjct: 48 IYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKY 107
Query: 413 KXTFTNIQINLVDVLEVDKENMTVRCEPLVTMGQLSRTXXXXXXXXXXXXXXDQLXXXXX 592
K T NI INL+D+LEVD + VR EPLVTMGQ++ D L
Sbjct: 108 KKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGL 167
Query: 593 XXXXXXXXXSHVHGLFQHVCLEYELVLADGSVVNCSKDENADLFYAVPWSYGTLGFLTSV 772
SH +GLFQH+C YELVLADGS V C+ EN+DLFYAVPWS GTLGFL +
Sbjct: 168 IMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAA 227
Query: 773 VIKVIPAKKYVRIHYYPFNNLSDLAKRFSQESLKPNPHQFVEALLYTXDSGVLMLGDMVD 952
I++IPAKKYV++ + P L + +F+ ES + H FVE LLY+ D V+M G M D
Sbjct: 228 EIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENH-FVEGLLYSLDEAVIMTGVMTD 286
Query: 953 EVGRXGKLNPIGVWHAEWFFKQVXXHXKXXARDKXYTS*KYY 1078
E KLN IG ++ WFFK V + K Y ++Y
Sbjct: 287 E-AEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHY 327
>AF398342-1|AAL15644.1| 516|Homo sapiens 3beta-hydroxysterol delta 24
reductase protein.
Length = 516
Score = 248 bits (607), Expect = 3e-65
Identities = 123/282 (43%), Positives = 160/282 (56%)
Frame = +2
Query: 233 LWSIIRHSVVFKLXXAPKXHXXKVKXVQXQIKAWLSGDKSTHLCTARPTWQTMSFRHSMY 412
++ +R VVFKL AP+ H +V+ +Q Q++ W T +CT RP W T+S R Y
Sbjct: 48 IYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKY 107
Query: 413 KXTFTNIQINLVDVLEVDKENMTVRCEPLVTMGQLSRTXXXXXXXXXXXXXXDQLXXXXX 592
K T NI INL+D+LEVD + VR EPLVTMGQ++ D L
Sbjct: 108 KKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGL 167
Query: 593 XXXXXXXXXSHVHGLFQHVCLEYELVLADGSVVNCSKDENADLFYAVPWSYGTLGFLTSV 772
SH +GLFQH+C YELVLADGS V C+ EN+DLFYAVPWS GTLGFL +
Sbjct: 168 IMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAA 227
Query: 773 VIKVIPAKKYVRIHYYPFNNLSDLAKRFSQESLKPNPHQFVEALLYTXDSGVLMLGDMVD 952
I++IPAKKYV++ + P L + +F+ ES + H FVE LLY+ D V+M G M D
Sbjct: 228 EIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENH-FVEGLLYSLDEAVIMTGVMTD 286
Query: 953 EVGRXGKLNPIGVWHAEWFFKQVXXHXKXXARDKXYTS*KYY 1078
E KLN IG ++ WFFK V + K Y ++Y
Sbjct: 287 E-AEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHY 327
>AF261758-1|AAG17288.1| 516|Homo sapiens seladin-1 protein.
Length = 516
Score = 248 bits (607), Expect = 3e-65
Identities = 123/282 (43%), Positives = 160/282 (56%)
Frame = +2
Query: 233 LWSIIRHSVVFKLXXAPKXHXXKVKXVQXQIKAWLSGDKSTHLCTARPTWQTMSFRHSMY 412
++ +R VVFKL AP+ H +V+ +Q Q++ W T +CT RP W T+S R Y
Sbjct: 48 IYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKY 107
Query: 413 KXTFTNIQINLVDVLEVDKENMTVRCEPLVTMGQLSRTXXXXXXXXXXXXXXDQLXXXXX 592
K T NI INL+D+LEVD + VR EPLVTMGQ++ D L
Sbjct: 108 KKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGL 167
Query: 593 XXXXXXXXXSHVHGLFQHVCLEYELVLADGSVVNCSKDENADLFYAVPWSYGTLGFLTSV 772
SH +GLFQH+C YELVLADGS V C+ EN+DLFYAVPWS GTLGFL +
Sbjct: 168 IMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAA 227
Query: 773 VIKVIPAKKYVRIHYYPFNNLSDLAKRFSQESLKPNPHQFVEALLYTXDSGVLMLGDMVD 952
I++IPAKKYV++ + P L + +F+ ES + H FVE LLY+ D V+M G M D
Sbjct: 228 EIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENH-FVEGLLYSLDEAVIMTGVMTD 286
Query: 953 EVGRXGKLNPIGVWHAEWFFKQVXXHXKXXARDKXYTS*KYY 1078
E KLN IG ++ WFFK V + K Y ++Y
Sbjct: 287 E-AEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHY 327
>AB073391-1|BAE45721.1| 427|Homo sapiens putative protein product of
Nbla03646 protein.
Length = 427
Score = 217 bits (531), Expect = 5e-56
Identities = 109/240 (45%), Positives = 137/240 (57%)
Frame = +2
Query: 359 LCTARPTWQTMSFRHSMYKXTFTNIQINLVDVLEVDKENMTVRCEPLVTMGQLSRTXXXX 538
+CT RP W T+S R YK T NI INL+D+LEVD + VR EPLVTMGQ++
Sbjct: 1 MCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSI 60
Query: 539 XXXXXXXXXXDQLXXXXXXXXXXXXXXSHVHGLFQHVCLEYELVLADGSVVNCSKDENAD 718
D L SH +GLFQH+C YELVLADGS V C+ EN+D
Sbjct: 61 GWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSD 120
Query: 719 LFYAVPWSYGTLGFLTSVVIKVIPAKKYVRIHYYPFNNLSDLAKRFSQESLKPNPHQFVE 898
LFYAVPWS GTLGFL + I++IPAKKYV++ + P L + +F+ ES + H FVE
Sbjct: 121 LFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENH-FVE 179
Query: 899 ALLYTXDSGVLMLGDMVDEVGRXGKLNPIGVWHAEWFFKQVXXHXKXXARDKXYTS*KYY 1078
LLY+ D V+M G M DE KLN IG ++ WFFK V + K Y ++Y
Sbjct: 180 GLLYSLDEAVIMTGVMTDE-AEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHY 238
>BC036604-1|AAH36604.2| 521|Homo sapiens D-2-hydroxyglutarate
dehydrogenase protein.
Length = 521
Score = 36.7 bits (81), Expect = 0.17
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Frame = +2
Query: 629 HGLFQHVCLEYELVLADGSVVNC----SKDENA-DLFYAVPWSYGTLGFLTSVVIKVIPA 793
+G L E+VLADG+V++C KD DL S GTLG +T+V I P
Sbjct: 216 YGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITTVSILCPPK 275
Query: 794 KKYVRIHYYPFNNLSDLAKRFS 859
+ V + + +++ + FS
Sbjct: 276 PRAVNVAFLGCPGFAEVLQTFS 297
>BC071598-1|AAH71598.1| 307|Homo sapiens D2HGDH protein protein.
Length = 307
Score = 34.3 bits (75), Expect = 0.90
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Frame = +2
Query: 629 HGLFQHVCLEYELVLADGSVVNC----SKDENA-DLFYAVPWSYGTLGFLTSVVIKVIPA 793
+G L E+VLADG+V++C KD DL S GTLG +T+V I P
Sbjct: 210 YGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITTVSILCPPK 269
Query: 794 KKYVRIHY 817
+ V + +
Sbjct: 270 PRAVNVAF 277
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 140,135,022
Number of Sequences: 237096
Number of extensions: 2808793
Number of successful extensions: 7031
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6517
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7013
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17009285070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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