Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP25_F_I12
(1203 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL353716-1|CAI14818.1| 346|Homo sapiens tubulin folding cofacto... 143 1e-33
U61234-1|AAB17539.1| 346|Homo sapiens cofactor C protein. 142 3e-33
BT007002-1|AAP35648.1| 346|Homo sapiens tubulin-specific chaper... 142 3e-33
BC020170-1|AAH20170.1| 346|Homo sapiens tubulin folding cofacto... 142 3e-33
BC017479-1|AAH17479.1| 346|Homo sapiens TBCC protein protein. 142 3e-33
BC053530-1|AAH53530.1| 350|Homo sapiens retinitis pigmentosa 2 ... 69 3e-11
BC043348-1|AAH43348.1| 350|Homo sapiens retinitis pigmentosa 2 ... 69 3e-11
AL627143-2|CAH70614.1| 350|Homo sapiens retinitis pigmentosa 2 ... 69 3e-11
AL050307-1|CAB82030.2| 350|Homo sapiens retinitis pigmentosa 2 ... 69 3e-11
AJ007590-1|CAA07577.1| 350|Homo sapiens XRP2 protein protein. 69 3e-11
BC025748-1|AAH25748.1| 557|Homo sapiens TBCC domain containing ... 47 1e-04
AK001422-1|BAA91682.1| 557|Homo sapiens protein ( Homo sapiens ... 47 1e-04
U37359-1|AAC78721.1| 680|Homo sapiens MRE11 homologue hMre11 pr... 31 6.3
BC063458-1|AAH63458.1| 708|Homo sapiens MRE11 meiotic recombina... 31 6.3
AY584241-1|AAS79320.1| 708|Homo sapiens MRE11 meiotic recombina... 31 6.3
AF303395-1|AAK18790.1| 708|Homo sapiens meiotic recombination 1... 31 6.3
AF073362-1|AAC36249.1| 708|Homo sapiens endo/exonuclease Mre11 ... 31 6.3
AF022778-1|AAD10197.1| 708|Homo sapiens DNA recombination and r... 31 6.3
>AL353716-1|CAI14818.1| 346|Homo sapiens tubulin folding cofactor C
protein.
Length = 346
Score = 143 bits (346), Expect = 1e-33
Identities = 89/286 (31%), Positives = 136/286 (47%), Gaps = 10/286 (3%)
Frame = +1
Query: 31 ISEYVEDLLAQVPTIDNSMLPSHFDIIKKEINELQKYVVTSTFFLKEFNLRKFLGIVQNL 210
++ +V + A ++ + + + LQK + S FFL ++LR+ + L
Sbjct: 61 VATFVRERAAVEELLERAESVERLEEAASRLQGLQKLINDSVFFLAAYDLRQGQEALARL 120
Query: 211 QTKCYELEDRYVPRXXXXXXXXXXXXXHSQKQNLMDEADGAAK--KDS---NKWDENL-- 369
Q E P+ S K + A + +DS K + +L
Sbjct: 121 QAALAERRRGLQPKKRFAFKTRGKDAASSTKVDAAPGIPPAVESIQDSPLPKKAEGDLGP 180
Query: 370 ---FGFSSKXXXXXXXXXXXXYRRDVALRNLKNCTIGLKGLMGTLHLINLENCIVLSGPV 540
GFS+ ++RDV L L NCT+ L G TL L +C +L GPV
Sbjct: 181 SWVCGFSNLESQVLEKRASELHQRDVLLTELSNCTVRLYGNPNTLRLTKAHSCKLLCGPV 240
Query: 541 TSSVFVDKCTNCKIVIACQQLRMHTSTKCDVYLHVTSKGIVEDCSQIRTAPYNLFYDNLE 720
++SVF++ C++C + +ACQQLR+H++ ++L VTS+ IVEDCS I+ APY Y ++
Sbjct: 241 STSVFLEDCSDCVLAVACQQLRIHSTKDTRIFLQVTSRAIVEDCSGIQFAPYTWSYPEID 300
Query: 721 KHYESSSLDRXXXXXXXXXXXXXXAPDVSSPNWSVLDVSERIDSWD 858
K +ESS LDR A D++SPNWS+L ER WD
Sbjct: 301 KDFESSGLDRSKNNWNDVDDFNWLARDMASPNWSILPEEERNIQWD 346
>U61234-1|AAB17539.1| 346|Homo sapiens cofactor C protein.
Length = 346
Score = 142 bits (343), Expect = 3e-33
Identities = 87/253 (34%), Positives = 125/253 (49%), Gaps = 10/253 (3%)
Frame = +1
Query: 130 LQKYVVTSTFFLKEFNLRKFLGIVQNLQTKCYELEDRYVPRXXXXXXXXXXXXXHSQKQN 309
LQK + S FFL ++LR+ + LQ E P+ S K +
Sbjct: 94 LQKLINDSVFFLAAYDLRQGQEALARLQAALAERRRGLQPKKRFAFKTRGKDAASSTKVD 153
Query: 310 LMDEADGAAK--KDS---NKWDENL-----FGFSSKXXXXXXXXXXXXYRRDVALRNLKN 459
A + +DS K + +L GFS+ ++RDV L L N
Sbjct: 154 AAPGIPPAVESIQDSPLPKKAEGDLGPSWVCGFSNLESQVLEKRASELHQRDVLLTELSN 213
Query: 460 CTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTSTKCDVYL 639
CT+ L G TL L +C +L GPV++SVF++ C++C + +ACQQLR+H++ ++L
Sbjct: 214 CTVRLYGNPNTLRLTKAHSCKLLCGPVSTSVFLEDCSDCVLAVACQQLRIHSTKDTRIFL 273
Query: 640 HVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSLDRXXXXXXXXXXXXXXAPDVSSPNW 819
VTS+ IVEDCS I+ APY Y ++K +ESS LDR A D++SPNW
Sbjct: 274 QVTSRAIVEDCSGIQFAPYTWSYPEIDKDFESSGLDRSKNNWNDVDDFNWLARDMASPNW 333
Query: 820 SVLDVSERIDSWD 858
S+L ER WD
Sbjct: 334 SILPEEERNIQWD 346
>BT007002-1|AAP35648.1| 346|Homo sapiens tubulin-specific chaperone
c protein.
Length = 346
Score = 142 bits (343), Expect = 3e-33
Identities = 87/253 (34%), Positives = 125/253 (49%), Gaps = 10/253 (3%)
Frame = +1
Query: 130 LQKYVVTSTFFLKEFNLRKFLGIVQNLQTKCYELEDRYVPRXXXXXXXXXXXXXHSQKQN 309
LQK + S FFL ++LR+ + LQ E P+ S K +
Sbjct: 94 LQKLINDSVFFLAAYDLRQGQEALARLQAALAERRRGLQPKKRFAFKTRGKDAASSTKVD 153
Query: 310 LMDEADGAAK--KDS---NKWDENL-----FGFSSKXXXXXXXXXXXXYRRDVALRNLKN 459
A + +DS K + +L GFS+ ++RDV L L N
Sbjct: 154 AAPGIPPAVESIQDSPLPKKAEGDLGPSWVCGFSNLESQVLEKRASELHQRDVLLTELSN 213
Query: 460 CTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTSTKCDVYL 639
CT+ L G TL L +C +L GPV++SVF++ C++C + +ACQQLR+H++ ++L
Sbjct: 214 CTVRLYGNPNTLRLTKAHSCKLLCGPVSTSVFLEDCSDCVLAVACQQLRIHSTKDTRIFL 273
Query: 640 HVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSLDRXXXXXXXXXXXXXXAPDVSSPNW 819
VTS+ IVEDCS I+ APY Y ++K +ESS LDR A D++SPNW
Sbjct: 274 QVTSRAIVEDCSGIQFAPYTWSYPEIDKDFESSGLDRSKNNWNDVDDFNWLARDMASPNW 333
Query: 820 SVLDVSERIDSWD 858
S+L ER WD
Sbjct: 334 SILPEEERNIQWD 346
>BC020170-1|AAH20170.1| 346|Homo sapiens tubulin folding cofactor C
protein.
Length = 346
Score = 142 bits (343), Expect = 3e-33
Identities = 87/253 (34%), Positives = 125/253 (49%), Gaps = 10/253 (3%)
Frame = +1
Query: 130 LQKYVVTSTFFLKEFNLRKFLGIVQNLQTKCYELEDRYVPRXXXXXXXXXXXXXHSQKQN 309
LQK + S FFL ++LR+ + LQ E P+ S K +
Sbjct: 94 LQKLINDSVFFLAAYDLRQGQEALARLQAALAERRRGLQPKKRFAFKTRGKDAASSTKVD 153
Query: 310 LMDEADGAAK--KDS---NKWDENL-----FGFSSKXXXXXXXXXXXXYRRDVALRNLKN 459
A + +DS K + +L GFS+ ++RDV L L N
Sbjct: 154 AAPGIPPAVESIQDSPLPKKAEGDLGPSWVCGFSNLESQVLEKRASELHQRDVLLTELSN 213
Query: 460 CTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTSTKCDVYL 639
CT+ L G TL L +C +L GPV++SVF++ C++C + +ACQQLR+H++ ++L
Sbjct: 214 CTVRLYGNPNTLRLTKAHSCKLLCGPVSTSVFLEDCSDCVLAVACQQLRIHSTKDTRIFL 273
Query: 640 HVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSLDRXXXXXXXXXXXXXXAPDVSSPNW 819
VTS+ IVEDCS I+ APY Y ++K +ESS LDR A D++SPNW
Sbjct: 274 QVTSRAIVEDCSGIQFAPYTWSYPEIDKDFESSGLDRSKNNWNDVDDFNWLARDMASPNW 333
Query: 820 SVLDVSERIDSWD 858
S+L ER WD
Sbjct: 334 SILPEEERNIQWD 346
>BC017479-1|AAH17479.1| 346|Homo sapiens TBCC protein protein.
Length = 346
Score = 142 bits (343), Expect = 3e-33
Identities = 87/253 (34%), Positives = 125/253 (49%), Gaps = 10/253 (3%)
Frame = +1
Query: 130 LQKYVVTSTFFLKEFNLRKFLGIVQNLQTKCYELEDRYVPRXXXXXXXXXXXXXHSQKQN 309
LQK + S FFL ++LR+ + LQ E P+ S K +
Sbjct: 94 LQKLINDSVFFLAAYDLRQGQEALARLQAALAERRRGLQPKKRFAFKTRGKDAASSTKVD 153
Query: 310 LMDEADGAAK--KDS---NKWDENL-----FGFSSKXXXXXXXXXXXXYRRDVALRNLKN 459
A + +DS K + +L GFS+ ++RDV L L N
Sbjct: 154 AAPGIPPAVESIQDSPLPKKAEGDLGPSWVCGFSNLESQVLEKRASELHQRDVLLTELSN 213
Query: 460 CTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTSTKCDVYL 639
CT+ L G TL L +C +L GPV++SVF++ C++C + +ACQQLR+H++ ++L
Sbjct: 214 CTVRLYGNPNTLRLTKAHSCKLLCGPVSTSVFLEDCSDCVLAVACQQLRIHSTKDTRIFL 273
Query: 640 HVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSLDRXXXXXXXXXXXXXXAPDVSSPNW 819
VTS+ IVEDCS I+ APY Y ++K +ESS LDR A D++SPNW
Sbjct: 274 QVTSRAIVEDCSGIQFAPYTWSYPEIDKDFESSGLDRSKNNWNDVDDFNWLARDMASPNW 333
Query: 820 SVLDVSERIDSWD 858
S+L ER WD
Sbjct: 334 SILPEEERNIQWD 346
>BC053530-1|AAH53530.1| 350|Homo sapiens retinitis pigmentosa 2
(X-linked recessive) protein.
Length = 350
Score = 68.9 bits (161), Expect = 3e-11
Identities = 31/101 (30%), Positives = 54/101 (53%)
Frame = +1
Query: 442 LRNLKNCTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTST 621
+++ +NC I + T+ + + NCI+ GPV SVF C +CK +ACQQ R+
Sbjct: 64 IQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCR 123
Query: 622 KCDVYLHVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSL 744
K +V+L ++ I+E S I+ + +Y L ++ + L
Sbjct: 124 KLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGL 164
>BC043348-1|AAH43348.1| 350|Homo sapiens retinitis pigmentosa 2
(X-linked recessive) protein.
Length = 350
Score = 68.9 bits (161), Expect = 3e-11
Identities = 31/101 (30%), Positives = 54/101 (53%)
Frame = +1
Query: 442 LRNLKNCTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTST 621
+++ +NC I + T+ + + NCI+ GPV SVF C +CK +ACQQ R+
Sbjct: 64 IQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCR 123
Query: 622 KCDVYLHVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSL 744
K +V+L ++ I+E S I+ + +Y L ++ + L
Sbjct: 124 KLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGL 164
>AL627143-2|CAH70614.1| 350|Homo sapiens retinitis pigmentosa 2
(X-linked recessive) protein.
Length = 350
Score = 68.9 bits (161), Expect = 3e-11
Identities = 31/101 (30%), Positives = 54/101 (53%)
Frame = +1
Query: 442 LRNLKNCTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTST 621
+++ +NC I + T+ + + NCI+ GPV SVF C +CK +ACQQ R+
Sbjct: 64 IQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCR 123
Query: 622 KCDVYLHVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSL 744
K +V+L ++ I+E S I+ + +Y L ++ + L
Sbjct: 124 KLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGL 164
>AL050307-1|CAB82030.2| 350|Homo sapiens retinitis pigmentosa 2
(X-linked recessive) protein.
Length = 350
Score = 68.9 bits (161), Expect = 3e-11
Identities = 31/101 (30%), Positives = 54/101 (53%)
Frame = +1
Query: 442 LRNLKNCTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTST 621
+++ +NC I + T+ + + NCI+ GPV SVF C +CK +ACQQ R+
Sbjct: 64 IQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCR 123
Query: 622 KCDVYLHVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSL 744
K +V+L ++ I+E S I+ + +Y L ++ + L
Sbjct: 124 KLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGL 164
>AJ007590-1|CAA07577.1| 350|Homo sapiens XRP2 protein protein.
Length = 350
Score = 68.9 bits (161), Expect = 3e-11
Identities = 31/101 (30%), Positives = 54/101 (53%)
Frame = +1
Query: 442 LRNLKNCTIGLKGLMGTLHLINLENCIVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTST 621
+++ +NC I + T+ + + NCI+ GPV SVF C +CK +ACQQ R+
Sbjct: 64 IQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCR 123
Query: 622 KCDVYLHVTSKGIVEDCSQIRTAPYNLFYDNLEKHYESSSL 744
K +V+L ++ I+E S I+ + +Y L ++ + L
Sbjct: 124 KLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGL 164
>BC025748-1|AAH25748.1| 557|Homo sapiens TBCC domain containing 1
protein.
Length = 557
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Frame = +1
Query: 451 LKNCTIGLKGLMGTLHLINLENC---IVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTST 621
+ C L+ L + +E C I + GPV +++ + C N K++ C +L + ++T
Sbjct: 334 IHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTT 393
Query: 622 KCDVYLHVTSKGIVEDCSQIRT-APYNLFYDNLEKHYESSSL 744
C ++ ++ ++ +Q T AP++ Y LE H + L
Sbjct: 394 GCIFHVLTPTRPLILSGNQTVTFAPFHTHYPMLEDHMARTGL 435
>AK001422-1|BAA91682.1| 557|Homo sapiens protein ( Homo sapiens
cDNA FLJ10560 fis, clone NT2RP2002621. ).
Length = 557
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Frame = +1
Query: 451 LKNCTIGLKGLMGTLHLINLENC---IVLSGPVTSSVFVDKCTNCKIVIACQQLRMHTST 621
+ C L+ L + +E C I + GPV +++ + C N K++ C +L + ++T
Sbjct: 334 IHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTT 393
Query: 622 KCDVYLHVTSKGIVEDCSQIRT-APYNLFYDNLEKHYESSSL 744
C ++ ++ ++ +Q T AP++ Y LE H + L
Sbjct: 394 GCIFHVLTPTRPLILSGNQTVTFAPFHTHYPMLEDHMARTGL 435
>U37359-1|AAC78721.1| 680|Homo sapiens MRE11 homologue hMre11
protein.
Length = 680
Score = 31.5 bits (68), Expect = 6.3
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = -2
Query: 872 LDHQSSHESILSETSKTDQFGELTSGANQLKSSKLSQLFEFLSKLDD 732
+D E I TSKTDQ TS + + S++S+ +F S DD
Sbjct: 618 VDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDD 664
>BC063458-1|AAH63458.1| 708|Homo sapiens MRE11 meiotic
recombination 11 homolog A (S. cerevisiae) protein.
Length = 708
Score = 31.5 bits (68), Expect = 6.3
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = -2
Query: 872 LDHQSSHESILSETSKTDQFGELTSGANQLKSSKLSQLFEFLSKLDD 732
+D E I TSKTDQ TS + + S++S+ +F S DD
Sbjct: 646 VDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDD 692
>AY584241-1|AAS79320.1| 708|Homo sapiens MRE11 meiotic
recombination 11 homolog A (S. cerevisiae) protein.
Length = 708
Score = 31.5 bits (68), Expect = 6.3
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = -2
Query: 872 LDHQSSHESILSETSKTDQFGELTSGANQLKSSKLSQLFEFLSKLDD 732
+D E I TSKTDQ TS + + S++S+ +F S DD
Sbjct: 646 VDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDD 692
>AF303395-1|AAK18790.1| 708|Homo sapiens meiotic recombination 11
protein.
Length = 708
Score = 31.5 bits (68), Expect = 6.3
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = -2
Query: 872 LDHQSSHESILSETSKTDQFGELTSGANQLKSSKLSQLFEFLSKLDD 732
+D E I TSKTDQ TS + + S++S+ +F S DD
Sbjct: 646 VDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDD 692
>AF073362-1|AAC36249.1| 708|Homo sapiens endo/exonuclease Mre11
protein.
Length = 708
Score = 31.5 bits (68), Expect = 6.3
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = -2
Query: 872 LDHQSSHESILSETSKTDQFGELTSGANQLKSSKLSQLFEFLSKLDD 732
+D E I TSKTDQ TS + + S++S+ +F S DD
Sbjct: 646 VDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDD 692
>AF022778-1|AAD10197.1| 708|Homo sapiens DNA recombination and
repair protein protein.
Length = 708
Score = 31.5 bits (68), Expect = 6.3
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = -2
Query: 872 LDHQSSHESILSETSKTDQFGELTSGANQLKSSKLSQLFEFLSKLDD 732
+D E I TSKTDQ TS + + S++S+ +F S DD
Sbjct: 646 VDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDD 692
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 135,355,258
Number of Sequences: 237096
Number of extensions: 2584336
Number of successful extensions: 7840
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 7617
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7835
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 16954238840
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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