Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP25_F_H20
(1192 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 201 3e-51
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 200 6e-51
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 200 6e-51
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 200 6e-51
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 200 6e-51
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 200 6e-51
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 200 6e-51
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 200 6e-51
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 200 6e-51
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 200 6e-51
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 200 6e-51
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 200 6e-51
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 200 1e-50
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 199 2e-50
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 195 3e-49
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 185 3e-46
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 185 3e-46
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 185 3e-46
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 185 3e-46
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 185 3e-46
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 185 3e-46
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 185 3e-46
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 183 1e-45
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 183 1e-45
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 181 5e-45
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 7e-45
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 180 7e-45
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 180 7e-45
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 180 7e-45
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 180 7e-45
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 180 7e-45
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 180 7e-45
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 180 7e-45
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 180 7e-45
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 180 7e-45
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 180 1e-44
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 1e-44
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 1e-44
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 180 1e-44
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 180 1e-44
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 180 1e-44
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 180 1e-44
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 180 1e-44
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 180 1e-44
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 180 1e-44
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 179 2e-44
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 179 2e-44
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 179 2e-44
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 179 2e-44
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 179 2e-44
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 179 2e-44
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 179 2e-44
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 178 3e-44
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 178 3e-44
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 178 3e-44
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 178 3e-44
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 178 3e-44
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 178 3e-44
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 177 6e-44
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 177 9e-44
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 175 3e-43
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 173 1e-42
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 173 1e-42
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 173 1e-42
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 173 1e-42
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 173 1e-42
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 173 1e-42
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 173 1e-42
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 173 1e-42
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 173 1e-42
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 172 2e-42
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 171 3e-42
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 171 3e-42
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 171 3e-42
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 167 7e-41
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 161 6e-39
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 161 6e-39
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 161 6e-39
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 161 6e-39
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 145 3e-34
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 145 3e-34
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 140 9e-33
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 135 3e-31
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 135 3e-31
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 111 4e-24
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 111 4e-24
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 111 4e-24
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 110 1e-23
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 109 3e-23
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 107 1e-22
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 76 3e-13
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 3e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 42 0.003
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 34 1.2
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 34 1.2
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.2
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.2
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 34 1.2
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.2
AL512443-2|CAH70059.1| 320|Homo sapiens zinc finger, RAN-bindin... 31 8.2
AL512443-1|CAH70058.1| 330|Homo sapiens zinc finger, RAN-bindin... 31 8.2
AK222858-1|BAD96578.1| 330|Homo sapiens zinc finger protein 265... 31 8.2
AB209568-1|BAD92805.1| 316|Homo sapiens zinc finger protein 265... 31 8.2
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 201 bits (491), Expect = 3e-51
Identities = 99/215 (46%), Positives = 140/215 (65%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P+ K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 200 bits (489), Expect = 6e-51
Identities = 99/215 (46%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 62 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 121
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 122 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 181
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 182 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 216
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 200 bits (487), Expect = 1e-50
Identities = 98/213 (46%), Positives = 138/213 (64%), Gaps = 3/213 (1%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+ +
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 543 TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP-K 719
V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 720 ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVE 893
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ+E
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Query: 894 CHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
CHPYLT L ++ + K I+++ + LGS P
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 199 bits (485), Expect = 2e-50
Identities = 98/215 (45%), Positives = 138/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P + G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 195 bits (475), Expect = 3e-49
Identities = 98/215 (45%), Positives = 138/215 (64%), Gaps = 3/215 (1%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 536
L L G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 537 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 716
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 717 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
S + S+ + +D ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 888 VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ECHPYLT L ++ + K I+++ + LGS P
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 185 bits (450), Expect = 3e-46
Identities = 98/215 (45%), Positives = 132/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 69
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 129
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 130 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 189
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 190 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 224
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 185 bits (450), Expect = 3e-46
Identities = 98/215 (45%), Positives = 132/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 185 bits (450), Expect = 3e-46
Identities = 98/215 (45%), Positives = 132/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 185 bits (450), Expect = 3e-46
Identities = 98/215 (45%), Positives = 132/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 185 bits (450), Expect = 3e-46
Identities = 98/215 (45%), Positives = 132/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 185 bits (450), Expect = 3e-46
Identities = 98/215 (45%), Positives = 132/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 185 bits (450), Expect = 3e-46
Identities = 98/215 (45%), Positives = 132/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 183 bits (446), Expect = 1e-45
Identities = 98/215 (45%), Positives = 131/215 (60%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 183 bits (445), Expect = 1e-45
Identities = 98/215 (45%), Positives = 131/215 (60%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 181 bits (440), Expect = 5e-45
Identities = 97/215 (45%), Positives = 131/215 (60%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWST HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 80
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 141 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 200
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 201 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 234
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 180 bits (439), Expect = 7e-45
Identities = 96/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 180 bits (437), Expect = 1e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 179 bits (436), Expect = 2e-44
Identities = 94/215 (43%), Positives = 133/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
++L G FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPYL L F + K+I+L LG++
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ 222
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 179 bits (436), Expect = 2e-44
Identities = 94/215 (43%), Positives = 133/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
++L G FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 126 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 185
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPYL L F + K+I+L LG++
Sbjct: 186 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ 220
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 179 bits (436), Expect = 2e-44
Identities = 94/215 (43%), Positives = 133/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
++L G FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPYL L F + K+I+L LG++
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ 222
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 179 bits (436), Expect = 2e-44
Identities = 94/215 (43%), Positives = 133/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
++L G FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPYL L F + K+I+L LG++
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ 222
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 179 bits (436), Expect = 2e-44
Identities = 94/215 (43%), Positives = 133/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
++L G FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPYL L F + K+I+L LG++
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ 222
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 179 bits (436), Expect = 2e-44
Identities = 94/215 (43%), Positives = 133/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
++L G FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPYL L F + K+I+L LG++
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ 222
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 179 bits (435), Expect = 2e-44
Identities = 94/215 (43%), Positives = 133/215 (61%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
++L G FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPYL L F + K+I+L LG++
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQ 222
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 178 bits (434), Expect = 3e-44
Identities = 92/207 (44%), Positives = 125/207 (60%), Gaps = 3/207 (1%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 740
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 741 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 911
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 912 XXXLHKFXEEKEIILSXFXVLGSKGTP 992
L ++ K I ++ + LGS P
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRP 219
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 178 bits (434), Expect = 3e-44
Identities = 95/214 (44%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ GY ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL++ K +P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 178 bits (434), Expect = 3e-44
Identities = 92/207 (44%), Positives = 125/207 (60%), Gaps = 3/207 (1%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 740
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 741 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 911
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 912 XXXLHKFXEEKEIILSXFXVLGSKGTP 992
L ++ K I ++ + LGS P
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRP 219
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 178 bits (434), Expect = 3e-44
Identities = 92/207 (44%), Positives = 125/207 (60%), Gaps = 3/207 (1%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 740
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 741 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 911
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 912 XXXLHKFXEEKEIILSXFXVLGSKGTP 992
L ++ K I ++ + LGS P
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRP 219
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 178 bits (434), Expect = 3e-44
Identities = 92/207 (44%), Positives = 125/207 (60%), Gaps = 3/207 (1%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 740
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 741 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 911
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 912 XXXLHKFXEEKEIILSXFXVLGSKGTP 992
L ++ K I ++ + LGS P
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRP 219
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 178 bits (434), Expect = 3e-44
Identities = 92/207 (44%), Positives = 125/207 (60%), Gaps = 3/207 (1%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 740
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 741 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 911
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 912 XXXLHKFXEEKEIILSXFXVLGSKGTP 992
L ++ K I ++ + LGS P
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRP 219
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 177 bits (431), Expect = 6e-44
Identities = 94/214 (43%), Positives = 130/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W ME GLAKSIGVSNFN ++ IL++ K +P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 177 bits (430), Expect = 9e-44
Identities = 93/215 (43%), Positives = 128/215 (59%), Gaps = 6/215 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G A+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 708 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSK 983
NQVECHPY L F + K+I+L + LGS+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQ 222
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 175 bits (425), Expect = 3e-43
Identities = 91/207 (43%), Positives = 123/207 (59%), Gaps = 3/207 (1%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 740
LFI KLW TF LV A +L D L + D++LIH P K G+ PK
Sbjct: 73 LFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 741 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 911
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 912 XXXLHKFXEEKEIILSXFXVLGSKGTP 992
L ++ K I ++ + LGS P
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRP 219
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 173 bits (421), Expect = 1e-42
Identities = 91/207 (43%), Positives = 128/207 (61%), Gaps = 6/207 (2%)
Frame = +3
Query: 381 MPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVR 551
MPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++KI DG+V+
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 552 RDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK-ISS 728
R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G + +PK +
Sbjct: 61 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENG 120
Query: 729 VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHP 902
+ + D W ME GLAKSIGVSNFN Q++ IL+K K KP NQVECHP
Sbjct: 121 KVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHP 180
Query: 903 YLTXXXLHKFXEEKEIILSXFXVLGSK 983
YL L F + K+I+L LG++
Sbjct: 181 YLNQSKLLDFCKSKDIVLVAHSALGTQ 207
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 173 bits (420), Expect = 1e-42
Identities = 92/208 (44%), Positives = 124/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 896
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 897 HPYLTXXXLHKFXEEKEIILSXFXVLGS 980
HPYL L + + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 172 bits (419), Expect = 2e-42
Identities = 92/214 (42%), Positives = 129/214 (60%), Gaps = 6/214 (2%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 527
+KL G FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 528 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
KI DG+V+R+++F KLW HR +L A SL +L L++ DL+LIH P+S+K G
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 708 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 878
IPK + I + D W +E LAKSIGVSNFN + ++ IL+K +VKP
Sbjct: 125 VIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPV 184
Query: 879 VNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
NQVECHPY L F + K+I+L + LGS
Sbjct: 185 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 218
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 171 bits (417), Expect = 3e-42
Identities = 93/221 (42%), Positives = 130/221 (58%), Gaps = 22/221 (9%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 707
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 708 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 860
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 861 G--KVKPAVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLG 977
+ KP NQ+ECHPYLT L F + +++ ++ + LG
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 171 bits (417), Expect = 3e-42
Identities = 93/221 (42%), Positives = 130/221 (58%), Gaps = 22/221 (9%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 707
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 708 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 860
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 861 G--KVKPAVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLG 977
+ KP NQ+ECHPYLT L F + +++ ++ + LG
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 171 bits (417), Expect = 3e-42
Identities = 93/221 (42%), Positives = 130/221 (58%), Gaps = 22/221 (9%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 707
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 708 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 860
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 861 G--KVKPAVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLG 977
+ KP NQ+ECHPYLT L F + +++ ++ + LG
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 167 bits (406), Expect = 7e-41
Identities = 89/204 (43%), Positives = 123/204 (60%), Gaps = 6/204 (2%)
Frame = +3
Query: 387 VIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRD 557
V+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++KI DG+V+R+
Sbjct: 1 VLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 558 ELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK-ISSVI 734
++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G IPK + I
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKI 120
Query: 735 QYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYL 908
+ D W +E GLAKSIGVSNFN Q++ IL+K K KP NQVECHPY
Sbjct: 121 LFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYF 180
Query: 909 TXXXLHKFXEEKEIILSXFXVLGS 980
L F + K+I+L + LGS
Sbjct: 181 NQRKLLDFCKSKDIVLVAYSALGS 204
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 161 bits (390), Expect = 6e-39
Identities = 89/219 (40%), Positives = 127/219 (57%), Gaps = 7/219 (3%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 524
+ L G +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 525 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 704
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 705 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 875
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 876 AVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
NQVECHPY T L KF ++ +I+++ + LG+ P
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 161 bits (390), Expect = 6e-39
Identities = 89/219 (40%), Positives = 127/219 (57%), Gaps = 7/219 (3%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 524
+ L G +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 525 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 704
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 705 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 875
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 876 AVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
NQVECHPY T L KF ++ +I+++ + LG+ P
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 161 bits (390), Expect = 6e-39
Identities = 89/219 (40%), Positives = 127/219 (57%), Gaps = 7/219 (3%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 524
+ L G +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 525 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 704
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 705 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 875
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 876 AVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
NQVECHPY T L KF ++ +I+++ + LG+ P
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 161 bits (390), Expect = 6e-39
Identities = 89/219 (40%), Positives = 127/219 (57%), Gaps = 7/219 (3%)
Frame = +3
Query: 357 LKLRXGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 524
+ L G +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 525 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 704
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 705 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 875
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 876 AVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
NQVECHPY T L KF ++ +I+++ + LG+ P
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 145 bits (351), Expect = 3e-34
Identities = 82/192 (42%), Positives = 112/192 (58%), Gaps = 22/192 (11%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 707
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 708 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 860
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 861 G--KVKPAVNQV 890
+ KP NQ+
Sbjct: 184 PGLRFKPLTNQI 195
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 145 bits (351), Expect = 3e-34
Identities = 82/192 (42%), Positives = 112/192 (58%), Gaps = 22/192 (11%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 707
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 708 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 860
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 861 G--KVKPAVNQV 890
+ KP NQ+
Sbjct: 184 PGLRFKPLTNQI 195
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 140 bits (339), Expect = 9e-33
Identities = 73/161 (45%), Positives = 98/161 (60%), Gaps = 3/161 (1%)
Frame = +3
Query: 507 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 686
+G AI++KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+
Sbjct: 27 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 86
Query: 687 SLKEGNSSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG 863
S+K G IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K
Sbjct: 87 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 146
Query: 864 --KVKPAVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGS 980
K KP NQVECHPY L F + K+I+L + LGS
Sbjct: 147 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 187
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 135 bits (327), Expect = 3e-31
Identities = 85/226 (37%), Positives = 123/226 (54%), Gaps = 8/226 (3%)
Frame = +3
Query: 339 VKEVATLKLRXGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 509
+K+ +++L G FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 510 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 689
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 690 LKE-GNSSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG 863
+K+ G +PK S I + D W +++ IL+K
Sbjct: 125 MKQPGKELLPKDASGEIILETVELCDTW-----------------------ELELILNKP 161
Query: 864 --KVKPAVNQ-VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ KP NQ VECHPYL L +F + K+I+L + LGS+ P
Sbjct: 162 GLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDP 207
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 135 bits (327), Expect = 3e-31
Identities = 85/226 (37%), Positives = 123/226 (54%), Gaps = 8/226 (3%)
Frame = +3
Query: 339 VKEVATLKLRXGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 509
+K+ +++L G FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 510 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 689
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 690 LKE-GNSSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG 863
+K+ G +PK S I + D W +++ IL+K
Sbjct: 125 MKQPGKELLPKDASGEIILETVELCDTW-----------------------ELELILNKP 161
Query: 864 --KVKPAVNQ-VECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
+ KP NQ VECHPYL L +F + K+I+L + LGS+ P
Sbjct: 162 GLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDP 207
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 111 bits (268), Expect = 4e-24
Identities = 55/122 (45%), Positives = 79/122 (64%), Gaps = 3/122 (2%)
Frame = +3
Query: 339 VKEVATLKLRXGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 509
+K+ +++L G FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 510 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 689
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 690 LK 695
+K
Sbjct: 125 MK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 111 bits (268), Expect = 4e-24
Identities = 55/122 (45%), Positives = 79/122 (64%), Gaps = 3/122 (2%)
Frame = +3
Query: 339 VKEVATLKLRXGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 509
+K+ +++L G FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 510 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 689
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 690 LK 695
+K
Sbjct: 125 MK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 111 bits (268), Expect = 4e-24
Identities = 55/122 (45%), Positives = 79/122 (64%), Gaps = 3/122 (2%)
Frame = +3
Query: 339 VKEVATLKLRXGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 509
+K+ +++L G FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 510 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 689
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 690 LK 695
+K
Sbjct: 125 MK 126
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 110 bits (264), Expect = 1e-23
Identities = 59/137 (43%), Positives = 79/137 (57%), Gaps = 2/137 (1%)
Frame = +3
Query: 363 LRXGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 542
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 543 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 719
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 720 -ISSVIQYSEFDYMDAW 767
I Y Y + W
Sbjct: 128 NADGTICYDSTHYKETW 144
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 109 bits (261), Expect = 3e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +3
Query: 381 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 560
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 561 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 695
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 107 bits (256), Expect = 1e-22
Identities = 53/127 (41%), Positives = 80/127 (62%), Gaps = 3/127 (2%)
Frame = +3
Query: 336 SVKEVATLKLRXGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKL 506
S + ++KL G FMP++ GT++ + E V+ AID+GYR ID+AY + NE+
Sbjct: 2 SFNRLLSVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 507 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 686
IG+AI+ KI +GTV+R ++F K+W TF R +LV+ +SL L L + DL+L H P+
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 687 SLKEGNS 707
L+ G S
Sbjct: 122 PLQPGRS 128
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 75.8 bits (178), Expect = 3e-13
Identities = 41/106 (38%), Positives = 59/106 (55%), Gaps = 3/106 (2%)
Frame = +3
Query: 684 MSLKEGNSSIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 860
M+ K G+ P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K
Sbjct: 1 MAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 60
Query: 861 G--KVKPAVNQVECHPYLTXXXLHKFXEEKEIILSXFXVLGSKGTP 992
K KP NQVECHPY T L KF ++ +I+++ + LG+ P
Sbjct: 61 PGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 106
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.0 bits (104), Expect = 3e-04
Identities = 25/48 (52%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Frame = +3
Query: 750 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 887
D W ME GLAKSIGVSNFN Q++ IL+K K KP NQ
Sbjct: 20 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +3
Query: 579 LWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 707
+W TF R +LV+ +SL L L + DL+L H P+ L+ G S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.2
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +3
Query: 714 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 890
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.2
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +3
Query: 714 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 890
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.2
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +3
Query: 714 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 890
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.2
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +3
Query: 714 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 890
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.2
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +3
Query: 714 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 890
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.2
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +3
Query: 714 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 890
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL512443-2|CAH70059.1| 320|Homo sapiens zinc finger, RAN-binding
domain containing 2 protein.
Length = 320
Score = 31.1 bits (67), Expect = 8.2
Identities = 26/84 (30%), Positives = 43/84 (51%)
Frame = +1
Query: 694 RKATVLYRRYHQ*SNTRSSTTWTPGSAWKTS*RKAWPRASGSATSIRPRSRRFWTKAKSS 873
R++ R H S++RSS+ + S ++ R + S S +S R RSR +K++SS
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
Query: 874 LPSIRSSVTHT*LXXASTSSXRKR 945
S R S + +S+SS +R
Sbjct: 260 SRSHRGSSSPRKRSYSSSSSSPER 283
>AL512443-1|CAH70058.1| 330|Homo sapiens zinc finger, RAN-binding
domain containing 2 protein.
Length = 330
Score = 31.1 bits (67), Expect = 8.2
Identities = 26/84 (30%), Positives = 43/84 (51%)
Frame = +1
Query: 694 RKATVLYRRYHQ*SNTRSSTTWTPGSAWKTS*RKAWPRASGSATSIRPRSRRFWTKAKSS 873
R++ R H S++RSS+ + S ++ R + S S +S R RSR +K++SS
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
Query: 874 LPSIRSSVTHT*LXXASTSSXRKR 945
S R S + +S+SS +R
Sbjct: 260 SRSHRGSSSPRKRSYSSSSSSPER 283
>AK222858-1|BAD96578.1| 330|Homo sapiens zinc finger protein 265
isoform 1 variant protein.
Length = 330
Score = 31.1 bits (67), Expect = 8.2
Identities = 26/84 (30%), Positives = 43/84 (51%)
Frame = +1
Query: 694 RKATVLYRRYHQ*SNTRSSTTWTPGSAWKTS*RKAWPRASGSATSIRPRSRRFWTKAKSS 873
R++ R H S++RSS+ + S ++ R + S S +S R RSR +K++SS
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
Query: 874 LPSIRSSVTHT*LXXASTSSXRKR 945
S R S + +S+SS +R
Sbjct: 260 SRSHRGSSSPRKRSYSSSSSSPER 283
>AB209568-1|BAD92805.1| 316|Homo sapiens zinc finger protein 265
isoform 1 variant protein.
Length = 316
Score = 31.1 bits (67), Expect = 8.2
Identities = 26/84 (30%), Positives = 43/84 (51%)
Frame = +1
Query: 694 RKATVLYRRYHQ*SNTRSSTTWTPGSAWKTS*RKAWPRASGSATSIRPRSRRFWTKAKSS 873
R++ R H S++RSS+ + S ++ R + S S +S R RSR +K++SS
Sbjct: 202 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 261
Query: 874 LPSIRSSVTHT*LXXASTSSXRKR 945
S R S + +S+SS +R
Sbjct: 262 SRSHRGSSSPRKRSYSSSSSSPER 285
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 132,157,625
Number of Sequences: 237096
Number of extensions: 2801115
Number of successful extensions: 12027
Number of sequences better than 10.0: 103
Number of HSP's better than 10.0 without gapping: 11277
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11858
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 16734053920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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