Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP25_F_H02
(1156 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein. 215 3e-55
BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein. 215 3e-55
BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrom... 215 3e-55
BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrom... 215 3e-55
AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging ... 215 3e-55
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 77 1e-13
AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containin... 77 1e-13
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 77 1e-13
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 77 1e-13
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 77 1e-13
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 77 1e-13
BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome... 71 1e-11
AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation... 71 1e-11
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 71 1e-11
AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome... 71 1e-11
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 71 1e-11
AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging ... 71 1e-11
AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging ... 71 1e-11
X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein. 64 9e-10
U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPa... 64 9e-10
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein. 64 9e-10
BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein. 64 9e-10
BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein. 64 9e-10
AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa GT... 64 9e-10
AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa GT... 64 9e-10
AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa GT... 64 9e-10
AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein. 64 9e-10
AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein. 64 9e-10
BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein. 62 4e-09
AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome... 62 4e-09
AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide exch... 62 4e-09
AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein. 62 4e-09
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 62 5e-09
AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein. 62 5e-09
AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein. 62 5e-09
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 62 5e-09
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 62 5e-09
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 56 2e-07
BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein. 56 3e-07
BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein. 56 3e-07
BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome... 56 3e-07
AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein pr... 56 3e-07
AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein. 56 3e-07
AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein. 56 3e-07
AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein. 55 4e-07
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 55 4e-07
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 54 1e-06
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 53 2e-06
BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating gu... 52 3e-06
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 52 3e-06
AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associat... 52 3e-06
AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associat... 52 3e-06
AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein. 52 4e-06
X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for ... 50 1e-05
X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for ... 50 1e-05
D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein. 50 1e-05
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t... 50 1e-05
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t... 50 1e-05
CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein. 50 1e-05
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga... 50 1e-05
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga... 50 1e-05
BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome... 50 1e-05
BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome... 50 1e-05
BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome... 50 1e-05
BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome... 50 1e-05
AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome... 50 1e-05
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein. 50 1e-05
AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome... 50 1e-05
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein. 50 1e-05
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 48 5e-05
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 48 5e-05
AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens ... 48 5e-05
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 48 6e-05
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 48 6e-05
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 48 6e-05
AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens ... 47 1e-04
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 46 2e-04
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 46 2e-04
BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein. 46 2e-04
BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein. 46 2e-04
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 46 2e-04
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 46 2e-04
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein. 46 3e-04
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein. 46 3e-04
AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein. 46 3e-04
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein. 46 3e-04
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein. 46 3e-04
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein. 46 3e-04
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein. 46 3e-04
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein. 46 3e-04
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with... 46 3e-04
AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens ... 45 6e-04
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein. 45 6e-04
AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2 pro... 43 0.002
AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein. 41 0.007
BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein. 38 0.091
AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containin... 38 0.091
AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containin... 38 0.091
BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein. 33 1.5
AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein. 33 1.5
>BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein.
Length = 358
Score = 215 bits (524), Expect = 3e-55
Identities = 109/256 (42%), Positives = 163/256 (63%), Gaps = 8/256 (3%)
Frame = +1
Query: 178 EELLPIFQYPISKSTDR-RVYVWGFAETGALGIH---LPRXXXXXXXXXXXXXLVWH-PM 342
E +P+ QY ++ RV+VWGF+ +GALG+ +P + P
Sbjct: 42 EAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPY 101
Query: 343 RSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHP--LELLL 516
R ++ I++ ACGYGFT+ S KT++ KV+G G+N DSQ+G+H R++ E +L
Sbjct: 102 RLELDQK--ISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVL 159
Query: 517 SYAPIYIPY-KSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
+P+ +P + E + V+ GRAH+++LTD+EGV+++GNN+YGQCGRKV NE Y S
Sbjct: 160 EPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSES 219
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
H +Q + +V V CGQDHSLF+T+ G+VY+CGWGADGQTGLG+Y+ S+PT + G
Sbjct: 220 HRVHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGG 278
Query: 874 DITTEKIVKVASTGDC 921
D+ +++VA+ GDC
Sbjct: 279 DLAGVNVIQVATYGDC 294
>BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein.
Length = 454
Score = 215 bits (524), Expect = 3e-55
Identities = 109/256 (42%), Positives = 163/256 (63%), Gaps = 8/256 (3%)
Frame = +1
Query: 178 EELLPIFQYPISKSTDR-RVYVWGFAETGALGIH---LPRXXXXXXXXXXXXXLVWH-PM 342
E +P+ QY ++ RV+VWGF+ +GALG+ +P + P
Sbjct: 42 EAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPY 101
Query: 343 RSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHP--LELLL 516
R ++ I++ ACGYGFT+ S KT++ KV+G G+N DSQ+G+H R++ E +L
Sbjct: 102 RLELDQK--ISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVL 159
Query: 517 SYAPIYIPY-KSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
+P+ +P + E + V+ GRAH+++LTD+EGV+++GNN+YGQCGRKV NE Y S
Sbjct: 160 EPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSES 219
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
H +Q + +V V CGQDHSLF+T+ G+VY+CGWGADGQTGLG+Y+ S+PT + G
Sbjct: 220 HRVHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGG 278
Query: 874 DITTEKIVKVASTGDC 921
D+ +++VA+ GDC
Sbjct: 279 DLAGVNVIQVATYGDC 294
Score = 31.5 bits (68), Expect = 6.0
Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-- 732
+++ A G +L + V+ G YG G+ N+ E M+ + L + N
Sbjct: 337 KVRQAACGGTGCAVLNGEGHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPE 393
Query: 733 --IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTP 858
+ + CG H +T G+++ G G G+G +++ P
Sbjct: 394 IQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFP 437
>BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 215 bits (524), Expect = 3e-55
Identities = 109/256 (42%), Positives = 163/256 (63%), Gaps = 8/256 (3%)
Frame = +1
Query: 178 EELLPIFQYPISKSTDR-RVYVWGFAETGALGIH---LPRXXXXXXXXXXXXXLVWH-PM 342
E +P+ QY ++ RV+VWGF+ +GALG+ +P + P
Sbjct: 42 EAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPY 101
Query: 343 RSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHP--LELLL 516
R ++ I++ ACGYGFT+ S KT++ KV+G G+N DSQ+G+H R++ E +L
Sbjct: 102 RLELDQK--ISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVL 159
Query: 517 SYAPIYIPY-KSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
+P+ +P + E + V+ GRAH+++LTD+EGV+++GNN+YGQCGRKV NE Y S
Sbjct: 160 EPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSES 219
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
H +Q + +V V CGQDHSLF+T+ G+VY+CGWGADGQTGLG+Y+ S+PT + G
Sbjct: 220 HRVHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGG 278
Query: 874 DITTEKIVKVASTGDC 921
D+ +++VA+ GDC
Sbjct: 279 DLAGVNVIQVATYGDC 294
Score = 31.9 bits (69), Expect = 4.5
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-- 732
+++ A G +L + V+ G YG G+ N+ E M+ + L + N
Sbjct: 337 KVRQAACGGTGCAVLNGEGHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPE 393
Query: 733 --IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
+ + CG H +T G+++ G G G+G +++ P V
Sbjct: 394 IQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRV 440
>BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 215 bits (524), Expect = 3e-55
Identities = 109/256 (42%), Positives = 163/256 (63%), Gaps = 8/256 (3%)
Frame = +1
Query: 178 EELLPIFQYPISKSTDR-RVYVWGFAETGALGIH---LPRXXXXXXXXXXXXXLVWH-PM 342
E +P+ QY ++ RV+VWGF+ +GALG+ +P + P
Sbjct: 42 EAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPY 101
Query: 343 RSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHP--LELLL 516
R ++ I++ ACGYGFT+ S KT++ KV+G G+N DSQ+G+H R++ E +L
Sbjct: 102 RLELDQK--ISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVL 159
Query: 517 SYAPIYIPY-KSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
+P+ +P + E + V+ GRAH+++LTD+EGV+++GNN+YGQCGRKV NE Y S
Sbjct: 160 EPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSES 219
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
H +Q + +V V CGQDHSLF+T+ G+VY+CGWGADGQTGLG+Y+ S+PT + G
Sbjct: 220 HRVHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGG 278
Query: 874 DITTEKIVKVASTGDC 921
D+ +++VA+ GDC
Sbjct: 279 DLAGVNVIQVATYGDC 294
Score = 31.9 bits (69), Expect = 4.5
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-- 732
+++ A G +L + V+ G YG G+ N+ E M+ + L + N
Sbjct: 337 KVRQAACGGTGCAVLNGEGHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPE 393
Query: 733 --IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
+ + CG H +T G+++ G G G+G +++ P V
Sbjct: 394 IQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRV 440
>AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging
factor-like protein protein.
Length = 464
Score = 215 bits (524), Expect = 3e-55
Identities = 109/256 (42%), Positives = 163/256 (63%), Gaps = 8/256 (3%)
Frame = +1
Query: 178 EELLPIFQYPISKSTDR-RVYVWGFAETGALGIH---LPRXXXXXXXXXXXXXLVWH-PM 342
E +P+ QY ++ RV+VWGF+ +GALG+ +P + P
Sbjct: 42 EAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPY 101
Query: 343 RSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHP--LELLL 516
R ++ I++ ACGYGFT+ S KT++ KV+G G+N DSQ+G+H R++ E +L
Sbjct: 102 RLELDQK--ISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVL 159
Query: 517 SYAPIYIPY-KSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
+P+ +P + E + V+ GRAH+++LTD+EGV+++GNN+YGQCGRKV NE Y S
Sbjct: 160 EPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSES 219
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
H +Q + +V V CGQDHSLF+T+ G+VY+CGWGADGQTGLG+Y+ S+PT + G
Sbjct: 220 HRVHRMQDFDGQ-VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGG 278
Query: 874 DITTEKIVKVASTGDC 921
D+ +++VA+ GDC
Sbjct: 279 DLAGVNVIQVATYGDC 294
Score = 31.9 bits (69), Expect = 4.5
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-- 732
+++ A G +L + V+ G YG G+ N+ E M+ + L + N
Sbjct: 337 KVRQAACGGTGCAVLNGEGHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPE 393
Query: 733 --IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
+ + CG H +T G+++ G G G+G +++ P V
Sbjct: 394 IQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRV 440
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 77.0 bits (181), Expect = 1e-13
Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 3/223 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
+VY WG G LG+ + P I +ACGY ++A
Sbjct: 104 QVYAWGLDSDGQLGL------------VGSEECIRVPRNIKSLSDIQIVQVACGYYHSLA 151
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRA 588
K SE VF G N Q+G + + LL + + IP+ VAAG A
Sbjct: 152 LSKASE---VFCWGQNKYGQLGLGTDCKKQTSPQLLK-SLLGIPFMQ-------VAAGGA 200
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H+ +LT ++ G N +GQ G + N+ Y V + ++ L + IV +CCG+DH+
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQKIVYICCGEDHTA 255
Query: 769 FITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
+T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 256 ALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 298
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 211 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 261
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 262 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 316
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 317 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 344
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/197 (29%), Positives = 89/197 (45%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P +S F + ++ CG TV + + V+ G N Q+G H R P
Sbjct: 21 IVLEPRKSDFFINKRVRDVGCGLRHTVFVL---DDGTVYTCGCNDLGQLG-HEKSRKKPE 76
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
+++ A I AV+ G AHT+ L DK VY G ++ GQ G V E
Sbjct: 77 QVVALDAQ----------NIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGL---VGSE- 122
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTA 864
+ V NI+ L IV V CG HSL ++++ +V+ G GQ GLG + T
Sbjct: 123 ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQ 182
Query: 865 VIGDITTEKIVKVASTG 915
++ + ++VA+ G
Sbjct: 183 LLKSLLGIPFMQVAAGG 199
>AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containing
protein 4 isoform 3 protein.
Length = 979
Score = 77.0 bits (181), Expect = 1e-13
Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 3/223 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
+VY WG G LG+ + P I +ACGY ++A
Sbjct: 104 QVYAWGLDSDGQLGL------------VGSEECIRVPRNIKSLSDIQIVQVACGYYHSLA 151
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRA 588
K SE VF G N Q+G + + LL + + IP+ VAAG A
Sbjct: 152 LSKASE---VFCWGQNKYGQLGLGTDCKKQTSPQLLK-SLLGIPFMQ-------VAAGGA 200
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H+ +LT ++ G N +GQ G + N+ Y V + ++ L + IV +CCG+DH+
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQKIVYICCGEDHTA 255
Query: 769 FITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
+T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 256 ALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 298
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 211 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 261
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 262 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 316
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 317 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 344
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/197 (29%), Positives = 89/197 (45%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P +S F + ++ CG TV + + V+ G N Q+G H R P
Sbjct: 21 IVLEPRKSDFFINKRVRDVGCGLRHTVFVL---DDGTVYTCGCNDLGQLG-HEKSRKKPE 76
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
+++ A I AV+ G AHT+ L DK VY G ++ GQ G V E
Sbjct: 77 QVVALDAQ----------NIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGL---VGSE- 122
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTA 864
+ V NI+ L IV V CG HSL ++++ +V+ G GQ GLG + T
Sbjct: 123 ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQ 182
Query: 865 VIGDITTEKIVKVASTG 915
++ + ++VA+ G
Sbjct: 183 LLKSLLGIPFMQVAAGG 199
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 77.0 bits (181), Expect = 1e-13
Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 3/223 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
+VY WG G LG+ + P I +ACGY ++A
Sbjct: 104 QVYAWGLDSDGQLGL------------VGSEECIRVPRNIKSLSDIQIVQVACGYYHSLA 151
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRA 588
K SE VF G N Q+G + + LL + + IP+ VAAG A
Sbjct: 152 LSKASE---VFCWGQNKYGQLGLGTDCKKQTSPQLLK-SLLGIPFMQ-------VAAGGA 200
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H+ +LT ++ G N +GQ G + N+ Y V + ++ L + IV +CCG+DH+
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQKIVYICCGEDHTA 255
Query: 769 FITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
+T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 256 ALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 298
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 211 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 261
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 262 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 316
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 317 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 344
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/197 (29%), Positives = 89/197 (45%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P +S F + ++ CG TV + + V+ G N Q+G H R P
Sbjct: 21 IVLEPRKSDFFINKRVRDVGCGLRHTVFVL---DDGTVYTCGCNDLGQLG-HEKSRKKPE 76
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
+++ A I AV+ G AHT+ L DK VY G ++ GQ G V E
Sbjct: 77 QVVALDAQ----------NIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGL---VGSE- 122
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTA 864
+ V NI+ L IV V CG HSL ++++ +V+ G GQ GLG + T
Sbjct: 123 ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQ 182
Query: 865 VIGDITTEKIVKVASTG 915
++ + ++VA+ G
Sbjct: 183 LLKSLLGIPFMQVAAGG 199
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 77.0 bits (181), Expect = 1e-13
Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 3/223 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
+VY WG G LG+ + P I +ACGY ++A
Sbjct: 104 QVYAWGLDSDGQLGL------------VGSEECIRVPRNIKSLSDIQIVQVACGYYHSLA 151
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRA 588
K SE VF G N Q+G + + LL + + IP+ VAAG A
Sbjct: 152 LSKASE---VFCWGQNKYGQLGLGTDCKKQTSPQLLK-SLLGIPFMQ-------VAAGGA 200
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H+ +LT ++ G N +GQ G + N+ Y V + ++ L + IV +CCG+DH+
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQKIVYICCGEDHTA 255
Query: 769 FITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
+T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 256 ALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 298
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 211 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 261
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 262 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 316
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 317 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 344
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/197 (29%), Positives = 89/197 (45%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P +S F + ++ CG TV + + V+ G N Q+G H R P
Sbjct: 21 IVLEPRKSDFFINKRVRDVGCGLRHTVFVL---DDGTVYTCGCNDLGQLG-HEKSRKKPE 76
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
+++ A I AV+ G AHT+ L DK VY G ++ GQ G V E
Sbjct: 77 QVVALDAQ----------NIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGL---VGSE- 122
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTA 864
+ V NI+ L IV V CG HSL ++++ +V+ G GQ GLG + T
Sbjct: 123 ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQ 182
Query: 865 VIGDITTEKIVKVASTG 915
++ + ++VA+ G
Sbjct: 183 LLKSLLGIPFMQVAAGG 199
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 77.0 bits (181), Expect = 1e-13
Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 3/223 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
+VY WG G LG+ + P I +ACGY ++A
Sbjct: 104 QVYAWGLDSDGQLGL------------VGSEECIRVPRNIKSLSDIQIVQVACGYYHSLA 151
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRA 588
K SE VF G N Q+G + + LL + + IP+ VAAG A
Sbjct: 152 LSKASE---VFCWGQNKYGQLGLGTDCKKQTSPQLLK-SLLGIPFMQ-------VAAGGA 200
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H+ +LT ++ G N +GQ G + N+ Y V + ++ L + IV +CCG+DH+
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQKIVYICCGEDHTA 255
Query: 769 FITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
+T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 256 ALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 298
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 211 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 261
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 262 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 316
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 317 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 344
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/197 (29%), Positives = 89/197 (45%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P +S F + ++ CG TV + + V+ G N Q+G H R P
Sbjct: 21 IVLEPRKSDFFINKRVRDVGCGLRHTVFVL---DDGTVYTCGCNDLGQLG-HEKSRKKPE 76
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
+++ A I AV+ G AHT+ L DK VY G ++ GQ G V E
Sbjct: 77 QVVALDAQ----------NIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGL---VGSE- 122
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTA 864
+ V NI+ L IV V CG HSL ++++ +V+ G GQ GLG + T
Sbjct: 123 ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQ 182
Query: 865 VIGDITTEKIVKVASTG 915
++ + ++VA+ G
Sbjct: 183 LLKSLLGIPFMQVAAGG 199
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 77.0 bits (181), Expect = 1e-13
Identities = 57/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I +ACGY ++A K SE VF G N Q+G + + LL + + IP+
Sbjct: 35 IVQVACGYYHSLALSKASE---VFCWGQNKYGQLGLGTDCKKQTSPQLLK-SLLGIPFMQ 90
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
VAAG AH+ +LT ++ G N +GQ G + N+ Y V + ++ L +
Sbjct: 91 -------VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQ 138
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
IV +CCG+DH+ +T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 139 KIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 194
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 107 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 157
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 158 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 212
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 213 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 240
Score = 50.8 bits (116), Expect = 9e-06
Identities = 36/135 (26%), Positives = 61/135 (45%)
Frame = +1
Query: 514 LSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
LSY I + +I VA G H++ L+ V+ G N YGQ G + ++
Sbjct: 19 LSYGRIRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQ 78
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
+ ++ L + V G HS +T SG ++ G GQ GL + ++R P ++
Sbjct: 79 L----LKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPN-LLK 133
Query: 874 DITTEKIVKVASTGD 918
+ ++KIV + D
Sbjct: 134 SLRSQKIVYICCGED 148
>BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
Frame = +1
Query: 379 IAC-GYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE 555
IAC YG + + + +VF G N SQ+G + NH L P +I
Sbjct: 100 IACLSYGSGPHIVLATTEGEVFTWGHNAYSQLG--NGTTNHGL------VPCHISTNLSN 151
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ VA G H+++LT V+ G N GQ G VN+ VT +Q + +
Sbjct: 152 KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP-RRVTGCLQ---NKVV 207
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V + CGQ + + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 208 VTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRV 251
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEG-VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+I ++ G I+L EG V+T G+NAY Q G + G + H L + +
Sbjct: 99 KIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNH----GLVPCHISTNLSNKQV 154
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
++V CG HSL +T G+V+A G+ GQ G G+ N+ P V G + + +V +A
Sbjct: 155 IEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQ 214
Query: 916 DC 921
C
Sbjct: 215 MC 216
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/180 (27%), Positives = 80/180 (44%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG + S+ + +VF G N Q+G S N P+ P +
Sbjct: 154 VIEVACG---SYHSLVLTSDGEVFAWGYNNSGQVGSGSTV-NQPI-------PRRVTGCL 202
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ + + D VY G N GQ G + N+ + L
Sbjct: 203 QNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQP-----TPCRVAALQGI 257
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ V CG H+L +T+ G+VYA G + GQ G GN N+S PT V + ++I+++A+
Sbjct: 258 RVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPV--TVEKDRIIEIAA 315
>AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation
1-like protein.
Length = 551
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
Frame = +1
Query: 379 IAC-GYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE 555
IAC YG + + + +VF G N SQ+G + NH L P +I
Sbjct: 100 IACLSYGSGPHIVLATTEGEVFTWGHNAYSQLG--NGTTNHGL------VPCHISTNLSN 151
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ VA G H+++LT V+ G N GQ G VN+ VT +Q + +
Sbjct: 152 KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP-RRVTGCLQ---NKVV 207
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V + CGQ + + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 208 VTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRV 251
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEG-VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+I ++ G I+L EG V+T G+NAY Q G + G + H L + +
Sbjct: 99 KIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNH----GLVPCHISTNLSNKQV 154
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
++V CG HSL +T G+V+A G+ GQ G G+ N+ P V G + + +V +A
Sbjct: 155 IEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQ 214
Query: 916 DC 921
C
Sbjct: 215 MC 216
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/180 (27%), Positives = 80/180 (44%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG + S+ + +VF G N Q+G S N P+ P +
Sbjct: 154 VIEVACG---SYHSLVLTSDGEVFAWGYNNSGQVGSGSTV-NQPI-------PRRVTGCL 202
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ + + D VY G N GQ G + N+ + L
Sbjct: 203 QNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQP-----TPCRVAALQGI 257
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ V CG H+L +T+ G+VYA G + GQ G GN N+S PT V + ++I+++A+
Sbjct: 258 RVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPV--TVEKDRIIEIAA 315
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 61 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 111
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 112 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 166
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 167 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 194
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
VAAG AH+ +LT ++ G N +GQ G + N+ Y V + ++ L + IV +CC
Sbjct: 45 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQKIVYICC 99
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
G+DH+ +T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 100 GEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 148
>AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
Frame = +1
Query: 379 IAC-GYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE 555
IAC YG + + + +VF G N SQ+G + NH L P +I
Sbjct: 100 IACLSYGSGPHIVLATTEGEVFTWGHNAYSQLG--NGTTNHGL------VPCHISTNLSN 151
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ VA G H+++LT V+ G N GQ G VN+ VT +Q + +
Sbjct: 152 KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP-RRVTGCLQ---NKVV 207
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V + CGQ + + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 208 VTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRV 251
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEG-VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+I ++ G I+L EG V+T G+NAY Q G + G + H L + +
Sbjct: 99 KIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNH----GLVPCHISTNLSNKQV 154
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
++V CG HSL +T G+V+A G+ GQ G G+ N+ P V G + + +V +A
Sbjct: 155 IEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQ 214
Query: 916 DC 921
C
Sbjct: 215 MC 216
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/180 (27%), Positives = 80/180 (44%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG + S+ + +VF G N Q+G S N P+ P +
Sbjct: 154 VIEVACG---SYHSLVLTSDGEVFAWGYNNSGQVGSGSTV-NQPI-------PRRVTGCL 202
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ + + D VY G N GQ G + N+ + L
Sbjct: 203 QNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQP-----TPCRVAALQGI 257
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ V CG H+L +T+ G+VYA G + GQ G GN N+S PT V + ++I+++A+
Sbjct: 258 RVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPV--TVEKDRIIEIAA 315
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 70.5 bits (165), Expect = 1e-11
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 1/148 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKE 615
+FG G N Q+G + + LL S I Y + G HT LT +
Sbjct: 61 IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVY---------ICCGEDHTAALTKEG 111
Query: 616 GVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDH-SLFITESGKV 792
GV+T G YGQ G +E + + +L + ++ CG+ H S F+ SG++
Sbjct: 112 GVFTFGAGGYGQLGHNSTSHE-----INPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 166
Query: 793 YACGWGADGQTGLGNYDNRSTPTAVIGD 876
Y+ G G +GQ G G+ NR +P V G+
Sbjct: 167 YSFGLGGNGQLGTGSTSNRKSPFTVKGN 194
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
VAAG AH+ +LT ++ G N +GQ G + N+ Y V + ++ L + IV +CC
Sbjct: 45 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRY----VPNLLKSLRSQKIVYICC 99
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV---IGDITTE 888
G+DH+ +T+ G V+ G G GQ G + + P V +G I TE
Sbjct: 100 GEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTE 148
>AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging
factor RLG protein.
Length = 551
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
Frame = +1
Query: 379 IAC-GYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE 555
IAC YG + + + +VF G N SQ+G + NH L P +I
Sbjct: 100 IACLSYGSGPHIVLATTEGEVFTWGHNAYSQLG--NGTTNHGL------VPCHISTNLSN 151
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ VA G H+++LT V+ G N GQ G VN+ VT +Q + +
Sbjct: 152 KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP-RRVTGCLQ---NKVV 207
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V + CGQ + + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 208 VTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRV 251
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEG-VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+I ++ G I+L EG V+T G+NAY Q G + G + H L + +
Sbjct: 99 KIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNH----GLVPCHISTNLSNKQV 154
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
++V CG HSL +T G+V+A G+ GQ G G+ N+ P V G + + +V +A
Sbjct: 155 IEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQ 214
Query: 916 DC 921
C
Sbjct: 215 MC 216
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/180 (27%), Positives = 80/180 (44%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG + S+ + +VF G N Q+G S N P+ P +
Sbjct: 154 VIEVACG---SYHSLVLTSDGEVFAWGYNNSGQVGSGSTV-NQPI-------PRRVTGCL 202
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ + + D VY G N GQ G + N+ + L
Sbjct: 203 QNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQP-----TPCRVAALQGI 257
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ V CG H+L +T+ G+VYA G + GQ G GN N+S PT V + ++I+++A+
Sbjct: 258 RVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPV--TVEKDRIIEIAA 315
>AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging
factor RLG variant protein.
Length = 556
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
Frame = +1
Query: 379 IAC-GYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE 555
IAC YG + + + +VF G N SQ+G + NH L P +I
Sbjct: 105 IACLSYGSGPHIVLATTEGEVFTWGHNAYSQLG--NGTTNHGL------VPCHISTNLSN 156
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ VA G H+++LT V+ G N GQ G VN+ VT +Q + +
Sbjct: 157 KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP-RRVTGCLQ---NKVV 212
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V + CGQ + + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 213 VTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRV 256
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 1/122 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEG-VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+I ++ G I+L EG V+T G+NAY Q G + G + H L + +
Sbjct: 104 KIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNH----GLVPCHISTNLSNKQV 159
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
++V CG HSL +T G+V+A G+ GQ G G+ N+ P V G + + +V +A
Sbjct: 160 IEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQ 219
Query: 916 DC 921
C
Sbjct: 220 MC 221
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/180 (27%), Positives = 80/180 (44%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG + S+ + +VF G N Q+G S N P+ P +
Sbjct: 159 VIEVACG---SYHSLVLTSDGEVFAWGYNNSGQVGSGSTV-NQPI-------PRRVTGCL 207
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ + + D VY G N GQ G + N+ + L
Sbjct: 208 QNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQP-----TPCRVAALQGI 262
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ V CG H+L +T+ G+VYA G + GQ G GN N+S PT V + ++I+++A+
Sbjct: 263 RVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPV--TVEKDRIIEIAA 320
>X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein.
Length = 815
Score = 64.1 bits (149), Expect = 9e-10
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Frame = +1
Query: 379 IACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRR-NHPLELLLSYAPIYIPYKSLE 555
I+CGY + A + T + VFG N ++G + NH L+S IP K ++
Sbjct: 195 ISCGY-YHSAFVTTDGELYVFGEPEN--GKLGLPNQLLGNHRTPQLVSE----IPEKVIQ 247
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
VA G HT++LT+ VYT G +GQ G + E + + I+ + + I
Sbjct: 248 -----VACGGEHTVVLTEN-AVYTFGLGQFGQLGLGTFLFETSEPKV----IENIRDQTI 297
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVAS 909
+ CG++H+ IT+ G +Y G G G+ GLG N+ N PT + IVK+ +
Sbjct: 298 SYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFL--RFIVKLVA 355
Query: 910 TGDC 921
G C
Sbjct: 356 CGGC 359
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/115 (33%), Positives = 60/115 (52%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
++ G H+ ++T +Y G+N +GQ G + + S T ++ L E + C
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG----LGSKSAISKPTC-VKALKPEKVKLAAC 94
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
G++H+L TE G VYA G +GQ GLG+ + R+T VI T+E +K S G
Sbjct: 95 GRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNT-FHVISFFTSEHKIKQLSAG 148
Score = 51.6 bits (118), Expect = 5e-06
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +1
Query: 544 KSLECE-IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
K+L+ E +K A GR HT++ T+ VY G N GQ G + EE H I
Sbjct: 82 KALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERN---TFHVISFF 136
Query: 721 GKEN-IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
E+ I + G + S +TE G+++ G ++GQ GL N N P V
Sbjct: 137 TSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQV 186
Score = 39.5 bits (88), Expect = 0.023
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V + CG +HS +T + K+Y G GQ GLG+ S PT V + EK VK+A+ G
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKA-LKPEK-VKLAACG 95
>U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPase
regulator protein.
Length = 815
Score = 64.1 bits (149), Expect = 9e-10
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Frame = +1
Query: 379 IACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRR-NHPLELLLSYAPIYIPYKSLE 555
I+CGY + A + T + VFG N ++G + NH L+S IP K ++
Sbjct: 195 ISCGY-YHSAFVTTDGELYVFGEPEN--GKLGLPNQLLGNHRTPQLVSE----IPEKVIQ 247
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
VA G HT++LT+ VYT G +GQ G + E + + I+ + + I
Sbjct: 248 -----VACGGEHTVVLTEN-AVYTFGLGQFGQLGLGTFLFETSEPKV----IENIRDQTI 297
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVAS 909
+ CG++H+ IT+ G +Y G G G+ GLG N+ N PT + IVK+ +
Sbjct: 298 SYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFL--RFIVKLVA 355
Query: 910 TGDC 921
G C
Sbjct: 356 CGGC 359
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/115 (33%), Positives = 60/115 (52%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
++ G H+ ++T +Y G+N +GQ G + + S T ++ L E + C
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG----LGSKSAISKPTC-VKALKPEKVKLAAC 94
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
G++H+L TE G VYA G +GQ GLG+ + R+T VI T+E +K S G
Sbjct: 95 GRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNT-FHVISFFTSEHKIKQLSAG 148
Score = 51.6 bits (118), Expect = 5e-06
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +1
Query: 544 KSLECE-IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
K+L+ E +K A GR HT++ T+ VY G N GQ G + EE H I
Sbjct: 82 KALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERN---TFHVISFF 136
Query: 721 GKEN-IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
E+ I + G + S +TE G+++ G ++GQ GL N N P V
Sbjct: 137 TSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQV 186
Score = 39.5 bits (88), Expect = 0.023
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V + CG +HS +T + K+Y G GQ GLG+ S PT V + EK VK+A+ G
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKA-LKPEK-VKLAACG 95
>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
Length = 1054
Score = 64.1 bits (149), Expect = 9e-10
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 1/182 (0%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P F + +ACG +V ++ E V+ G+NT Q+G H N P
Sbjct: 25 IVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGE---VYTCGLNTKGQLG-HEREGNKP- 79
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
E + + A +I + VA G +H++ L+D+ +++ G + GQ G + E+
Sbjct: 80 EQIGALADQHIIH---------VACGESHSLALSDRGQLFSWGAGSDGQLG--LMTTED- 127
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLG-NYDNRSTPT 861
V IQKL ++ I+ V CG H L + G+ + G + GQ GLG + ++++P
Sbjct: 128 -SVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQ 186
Query: 862 AV 867
V
Sbjct: 187 RV 188
Score = 64.1 bits (149), Expect = 9e-10
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
+K VA G H++ L + VYT G N GQ G + N+ I L ++I+
Sbjct: 40 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKP-------EQIGALADQHIIH 92
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V CG+ HSL +++ G++++ G G+DGQ GL ++ +I + + I++V+
Sbjct: 93 VACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVS 147
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/122 (28%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Frame = +1
Query: 544 KSLE-CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
+SLE + VAAG AH+ L+ V+ G N GQ G +++E H ++ L
Sbjct: 189 RSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLG----LSDEKDRESPCH-VKLL 243
Query: 721 GKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVK 900
+ +V + CG++H+ +T+SG V+ G G+ GQ G + ++ P V+ ++ ++ +
Sbjct: 244 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVL-ELMGSEVTQ 302
Query: 901 VA 906
+A
Sbjct: 303 IA 304
Score = 45.2 bits (102), Expect = 5e-04
Identities = 20/63 (31%), Positives = 33/63 (52%)
Frame = +1
Query: 718 LGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIV 897
+ ++ +V CG +HS+F+ E G+VY CG GQ G ++ IG + + I+
Sbjct: 35 ISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLG---HEREGNKPEQIGALADQHII 91
Query: 898 KVA 906
VA
Sbjct: 92 HVA 94
>BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein.
Length = 368
Score = 64.1 bits (149), Expect = 9e-10
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 1/182 (0%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P F + +ACG +V ++ E V+ G+NT Q+G H N P
Sbjct: 21 IVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGE---VYTCGLNTKGQLG-HEREGNKP- 75
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
E + + A +I + VA G +H++ L+D+ +++ G + GQ G + E+
Sbjct: 76 EQIGALADQHIIH---------VACGESHSLALSDRGQLFSWGAGSDGQLG--LMTTED- 123
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLG-NYDNRSTPT 861
V IQKL ++ I+ V CG H L + G+ + G + GQ GLG + ++++P
Sbjct: 124 -SVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQ 182
Query: 862 AV 867
V
Sbjct: 183 RV 184
Score = 64.1 bits (149), Expect = 9e-10
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
+K VA G H++ L + VYT G N GQ G + N+ I L ++I+
Sbjct: 36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKP-------EQIGALADQHIIH 88
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V CG+ HSL +++ G++++ G G+DGQ GL ++ +I + + I++V+
Sbjct: 89 VACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVS 143
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/122 (28%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Frame = +1
Query: 544 KSLE-CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
+SLE + VAAG AH+ L+ V+ G N GQ G +++E H ++ L
Sbjct: 185 RSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLG----LSDEKDRESPCH-VKLL 239
Query: 721 GKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVK 900
+ +V + CG++H+ +T+SG V+ G G+ GQ G + ++ P V+ ++ ++ +
Sbjct: 240 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVL-ELMGSEVTQ 298
Query: 901 VA 906
+A
Sbjct: 299 IA 300
Score = 45.2 bits (102), Expect = 5e-04
Identities = 20/63 (31%), Positives = 33/63 (52%)
Frame = +1
Query: 718 LGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIV 897
+ ++ +V CG +HS+F+ E G+VY CG GQ G ++ IG + + I+
Sbjct: 31 ISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLG---HEREGNKPEQIGALADQHII 87
Query: 898 KVA 906
VA
Sbjct: 88 HVA 90
>BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein.
Length = 480
Score = 64.1 bits (149), Expect = 9e-10
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Frame = +1
Query: 379 IACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRR-NHPLELLLSYAPIYIPYKSLE 555
I+CGY + A + T + VFG N ++G + NH L+S IP K ++
Sbjct: 195 ISCGY-YHSAFVTTDGELYVFGEPEN--GKLGLPNQLLGNHRTPQLVSE----IPEKVIQ 247
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
VA G HT++LT+ VYT G +GQ G + E + + I+ + + I
Sbjct: 248 -----VACGGEHTVVLTEN-AVYTFGLGQFGQLGLGTFLFETSEPKV----IENIRDQTI 297
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVAS 909
+ CG++H+ IT+ G +Y G G G+ GLG N+ N PT + IVK+ +
Sbjct: 298 SYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFL--RFIVKLVA 355
Query: 910 TGDC 921
G C
Sbjct: 356 CGGC 359
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/115 (33%), Positives = 60/115 (52%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
++ G H+ ++T +Y G+N +GQ G + + S T ++ L E + C
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG----LGSKSAISKPTC-VKALKPEKVKLAAC 94
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
G++H+L TE G VYA G +GQ GLG+ + R+T VI T+E +K S G
Sbjct: 95 GRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNT-FHVISFFTSEHKIKQLSAG 148
Score = 51.6 bits (118), Expect = 5e-06
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +1
Query: 544 KSLECE-IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
K+L+ E +K A GR HT++ T+ VY G N GQ G + EE H I
Sbjct: 82 KALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERN---TFHVISFF 136
Query: 721 GKEN-IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
E+ I + G + S +TE G+++ G ++GQ GL N N P V
Sbjct: 137 TSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQV 186
Score = 39.5 bits (88), Expect = 0.023
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V + CG +HS +T + K+Y G GQ GLG+ S PT V + EK VK+A+ G
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKA-LKPEK-VKLAACG 95
>AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 64.1 bits (149), Expect = 9e-10
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Frame = +1
Query: 379 IACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRR-NHPLELLLSYAPIYIPYKSLE 555
I+CGY + A + T + VFG N ++G + NH L+S IP K ++
Sbjct: 195 ISCGY-YHSAFVTTDGELYVFGEPEN--GKLGLPNQLLGNHRTPQLVSE----IPEKVIQ 247
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
VA G HT++LT+ VYT G +GQ G + E + + I+ + + I
Sbjct: 248 -----VACGGEHTVVLTEN-AVYTFGLGQFGQLGLGTFLFETSEPKV----IENIRDQTI 297
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVAS 909
+ CG++H+ IT+ G +Y G G G+ GLG N+ N PT + IVK+ +
Sbjct: 298 SYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFL--RFIVKLVA 355
Query: 910 TGDC 921
G C
Sbjct: 356 CGGC 359
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/115 (33%), Positives = 60/115 (52%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
++ G H+ ++T +Y G+N +GQ G + + S T ++ L E + C
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG----LGSKSAISKPTC-VKALKPEKVKLAAC 94
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
G++H+L TE G VYA G +GQ GLG+ + R+T VI T+E +K S G
Sbjct: 95 GRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNT-FHVISFFTSEHKIKQLSAG 148
Score = 51.6 bits (118), Expect = 5e-06
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +1
Query: 544 KSLECE-IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
K+L+ E +K A GR HT++ T+ VY G N GQ G + EE H I
Sbjct: 82 KALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERN---TFHVISFF 136
Query: 721 GKEN-IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
E+ I + G + S +TE G+++ G ++GQ GL N N P V
Sbjct: 137 TSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQV 186
Score = 39.5 bits (88), Expect = 0.023
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V + CG +HS +T + K+Y G GQ GLG+ S PT V + EK VK+A+ G
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKA-LKPEK-VKLAACG 95
>AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator variant protein.
Length = 815
Score = 64.1 bits (149), Expect = 9e-10
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Frame = +1
Query: 379 IACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRR-NHPLELLLSYAPIYIPYKSLE 555
I+CGY + A + T + VFG N ++G + NH L+S IP K ++
Sbjct: 195 ISCGY-YHSAFVTTDGELYVFGEPEN--GKLGLPNQLLGNHRTPQLVSE----IPEKVIQ 247
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
VA G HT++LT+ VYT G +GQ G + E + + I+ + + I
Sbjct: 248 -----VACGGEHTVVLTEN-AVYTFGLGQFGQLGLGTFLFETSEPKV----IENIRDQTI 297
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVAS 909
+ CG++H+ IT+ G +Y G G G+ GLG N+ N PT + IVK+ +
Sbjct: 298 SYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFL--RFIVKLVA 355
Query: 910 TGDC 921
G C
Sbjct: 356 CGGC 359
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/115 (33%), Positives = 60/115 (52%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
++ G H+ ++T +Y G+N +GQ G + + S T ++ L E + C
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG----LGSKSAISKPTC-VKALKPEKVKLAAC 94
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
G++H+L TE G VYA G +GQ GLG+ + R+T VI T+E +K S G
Sbjct: 95 GRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNT-FHVISFFTSEHKIKQLSAG 148
Score = 51.6 bits (118), Expect = 5e-06
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +1
Query: 544 KSLECE-IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
K+L+ E +K A GR HT++ T+ VY G N GQ G + EE H I
Sbjct: 82 KALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERN---TFHVISFF 136
Query: 721 GKEN-IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
E+ I + G + S +TE G+++ G ++GQ GL N N P V
Sbjct: 137 TSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQV 186
Score = 39.5 bits (88), Expect = 0.023
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V + CG +HS +T + K+Y G GQ GLG+ S PT V + EK VK+A+ G
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKA-LKPEK-VKLAACG 95
>AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 64.1 bits (149), Expect = 9e-10
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Frame = +1
Query: 379 IACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRR-NHPLELLLSYAPIYIPYKSLE 555
I+CGY + A + T + VFG N ++G + NH L+S IP K ++
Sbjct: 195 ISCGY-YHSAFVTTDGELYVFGEPEN--GKLGLPNQLLGNHRTPQLVSE----IPEKVIQ 247
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
VA G HT++LT+ VYT G +GQ G + E + + I+ + + I
Sbjct: 248 -----VACGGEHTVVLTEN-AVYTFGLGQFGQLGLGTFLFETSEPKV----IENIRDQTI 297
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVAS 909
+ CG++H+ IT+ G +Y G G G+ GLG N+ N PT + IVK+ +
Sbjct: 298 SYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFL--RFIVKLVA 355
Query: 910 TGDC 921
G C
Sbjct: 356 CGGC 359
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/115 (33%), Positives = 60/115 (52%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
++ G H+ ++T +Y G+N +GQ G + + S T ++ L E + C
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG----LGSKSAISKPTC-VKALKPEKVKLAAC 94
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
G++H+L TE G VYA G +GQ GLG+ + R+T VI T+E +K S G
Sbjct: 95 GRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNT-FHVISFFTSEHKIKQLSAG 148
Score = 51.6 bits (118), Expect = 5e-06
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +1
Query: 544 KSLECE-IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
K+L+ E +K A GR HT++ T+ VY G N GQ G + EE H I
Sbjct: 82 KALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERN---TFHVISFF 136
Query: 721 GKEN-IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
E+ I + G + S +TE G+++ G ++GQ GL N N P V
Sbjct: 137 TSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQV 186
Score = 39.5 bits (88), Expect = 0.023
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V + CG +HS +T + K+Y G GQ GLG+ S PT V + EK VK+A+ G
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKA-LKPEK-VKLAACG 95
>AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein.
Length = 646
Score = 64.1 bits (149), Expect = 9e-10
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Frame = +1
Query: 379 IACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRR-NHPLELLLSYAPIYIPYKSLE 555
I+CGY + A + T + VFG N ++G + NH L+S IP K ++
Sbjct: 195 ISCGY-YHSAFVTTDGELYVFGEPEN--GKLGLPNQLLGNHRTPQLVSE----IPEKVIQ 247
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
VA G HT++LT+ VYT G +GQ G + E + + I+ + + I
Sbjct: 248 -----VACGGEHTVVLTEN-AVYTFGLGQFGQLGLGTFLFETSEPKV----IENIRDQTI 297
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVAS 909
+ CG++H+ IT+ G +Y G G G+ GLG N+ N PT + IVK+ +
Sbjct: 298 SYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFL--RFIVKLVA 355
Query: 910 TGDC 921
G C
Sbjct: 356 CGGC 359
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/115 (33%), Positives = 60/115 (52%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
++ G H+ ++T +Y G+N +GQ G + + S T ++ L E + C
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG----LGSKSAISKPTC-VKALKPEKVKLAAC 94
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
G++H+L TE G VYA G +GQ GLG+ + R+T VI T+E +K S G
Sbjct: 95 GRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNT-FHVISFFTSEHKIKQLSAG 148
Score = 51.6 bits (118), Expect = 5e-06
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +1
Query: 544 KSLECE-IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
K+L+ E +K A GR HT++ T+ VY G N GQ G + EE H I
Sbjct: 82 KALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERN---TFHVISFF 136
Query: 721 GKEN-IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
E+ I + G + S +TE G+++ G ++GQ GL N N P V
Sbjct: 137 TSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQV 186
Score = 39.5 bits (88), Expect = 0.023
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V + CG +HS +T + K+Y G GQ GLG+ S PT V + EK VK+A+ G
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKA-LKPEK-VKLAACG 95
>AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein.
Length = 382
Score = 64.1 bits (149), Expect = 9e-10
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 1/182 (0%)
Frame = +1
Query: 325 LVWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPL 504
+V P F + +ACG +V ++ E V+ G+NT Q+G H N P
Sbjct: 21 IVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGE---VYTCGLNTKGQLG-HEREGNKP- 75
Query: 505 ELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEY 684
E + + A +I + VA G +H++ L+D+ +++ G + GQ G + E+
Sbjct: 76 EQIGALADQHIIH---------VACGESHSLALSDRGQLFSWGAGSDGQLG--LMTTED- 123
Query: 685 KGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLG-NYDNRSTPT 861
V IQKL ++ I+ V CG H L + G+ + G + GQ GLG + ++++P
Sbjct: 124 -SVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQ 182
Query: 862 AV 867
V
Sbjct: 183 RV 184
Score = 64.1 bits (149), Expect = 9e-10
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
+K VA G H++ L + VYT G N GQ G + N+ I L ++I+
Sbjct: 36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKP-------EQIGALADQHIIH 88
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V CG+ HSL +++ G++++ G G+DGQ GL ++ +I + + I++V+
Sbjct: 89 VACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVS 143
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/122 (28%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Frame = +1
Query: 544 KSLE-CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL 720
+SLE + VAAG AH+ L+ V+ G N GQ G +++E H ++ L
Sbjct: 185 RSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLG----LSDEKDRESPCH-VKLL 239
Query: 721 GKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVK 900
+ +V + CG++H+ +T+SG V+ G G+ GQ G + ++ P V+ ++ ++ +
Sbjct: 240 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVL-ELMGSEVTQ 298
Query: 901 VA 906
+A
Sbjct: 299 IA 300
Score = 45.2 bits (102), Expect = 5e-04
Identities = 20/63 (31%), Positives = 33/63 (52%)
Frame = +1
Query: 718 LGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIV 897
+ ++ +V CG +HS+F+ E G+VY CG GQ G ++ IG + + I+
Sbjct: 31 ISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLG---HEREGNKPEQIGALADQHII 87
Query: 898 KVA 906
VA
Sbjct: 88 HVA 90
>BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein.
Length = 355
Score = 62.1 bits (144), Expect = 4e-09
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGV-YTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+IK+++ G ++L+ ++GV Y G+N Y Q G N+ V N+ L K+ +
Sbjct: 75 KIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTT-NQGIATVQVCTNL--LIKQ-V 130
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V+V CG HS+ + G+V+A G+ GQ G G+ N+ TP V + +++V +A
Sbjct: 131 VEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIA 187
Score = 58.8 bits (136), Expect = 3e-08
Identities = 43/159 (27%), Positives = 70/159 (44%)
Frame = +1
Query: 391 YGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKA 570
YG + ++E V+ G N SQ+G + + A + + L ++
Sbjct: 81 YGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQG--------IATVQVCTNLLIKQVVE 132
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
VA G H++ L V+ G N GQ G N+ + L + +V + C
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNC----LHIKRVVGIAC 188
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
GQ S+ + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 58.8 bits (136), Expect = 3e-08
Identities = 47/180 (26%), Positives = 81/180 (45%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG ++A E VF G N Q+G S N P ++ ++I
Sbjct: 130 VVEVACGSHHSMALAADGE---VFAWGYNNCGQVGSGSTA-NQPTPRKVTNC-LHIK--- 181
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ ++ + D VY G N GQ G N N+ + + L
Sbjct: 182 ---RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-----LTPVRVAALHSV 233
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ + CG H+L +T+ G +YA G GQ G GN +N +P ++ + E++V++A+
Sbjct: 234 CVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIM--VEKERVVEIAA 291
>AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 531
Score = 62.1 bits (144), Expect = 4e-09
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGV-YTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+IK+++ G ++L+ ++GV Y G+N Y Q G N+ V N+ L K+ +
Sbjct: 75 KIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTT-NQGIAPVQVCTNL--LIKQ-V 130
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V+V CG HS+ + G+V+A G+ GQ G G+ N+ TP V + +++V +A
Sbjct: 131 VEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIA 187
Score = 62.1 bits (144), Expect = 4e-09
Identities = 44/159 (27%), Positives = 71/159 (44%)
Frame = +1
Query: 391 YGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKA 570
YG + ++E V+ G N SQ+G + + AP+ + L ++
Sbjct: 81 YGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQG--------IAPVQVCTNLLIKQVVE 132
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
VA G H++ L V+ G N GQ G N+ + L + +V + C
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNC----LHIKRVVGIAC 188
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
GQ S+ + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 58.8 bits (136), Expect = 3e-08
Identities = 47/180 (26%), Positives = 81/180 (45%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG ++A E VF G N Q+G S N P ++ ++I
Sbjct: 130 VVEVACGSHHSMALAADGE---VFAWGYNNCGQVGSGSTA-NQPTPRKVTNC-LHIK--- 181
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ ++ + D VY G N GQ G N N+ + + L
Sbjct: 182 ---RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-----LTPVRVAALHSV 233
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ + CG H+L +T+ G +YA G GQ G GN +N +P ++ + E++V++A+
Sbjct: 234 CVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIM--VEKERVVEIAA 291
>AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39335 fis, clone OCBBF2017398, moderately
similar to Homo sapiens RCC1-like G exchanging factor
RLG mRNA. ).
Length = 531
Score = 62.1 bits (144), Expect = 4e-09
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGV-YTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+IK+++ G ++L+ ++GV Y G+N Y Q G N+ V N+ L K+ +
Sbjct: 75 KIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTT-NQGIAPVQVCTNL--LIKQ-V 130
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V+V CG HS+ + G+V+A G+ GQ G G+ N+ TP V + +++V +A
Sbjct: 131 VEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIA 187
Score = 62.1 bits (144), Expect = 4e-09
Identities = 44/159 (27%), Positives = 71/159 (44%)
Frame = +1
Query: 391 YGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKA 570
YG + ++E V+ G N SQ+G + + AP+ + L ++
Sbjct: 81 YGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQG--------IAPVQVCTNLLIKQVVE 132
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
VA G H++ L V+ G N GQ G N+ + L + +V + C
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNC----LHIKRVVGIAC 188
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
GQ S+ + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 58.8 bits (136), Expect = 3e-08
Identities = 47/180 (26%), Positives = 81/180 (45%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG ++A E VF G N Q+G S N P ++ ++I
Sbjct: 130 VVEVACGSHHSMALAADGE---VFAWGYNNCGQVGSGSTA-NQPTPRKVTNC-LHIK--- 181
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ ++ + D VY G N GQ G N N+ + + L
Sbjct: 182 ---RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-----LTPVRVAALHSV 233
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ + CG H+L +T+ G +YA G GQ G GN +N +P ++ + E++V++A+
Sbjct: 234 CVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIM--VEKERVVEIAA 291
>AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 531
Score = 62.1 bits (144), Expect = 4e-09
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGV-YTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+IK+++ G ++L+ ++GV Y G+N Y Q G N+ V N+ L K+ +
Sbjct: 75 KIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTT-NQGIAPVQVCTNL--LIKQ-V 130
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V+V CG HS+ + G+V+A G+ GQ G G+ N+ TP V + +++V +A
Sbjct: 131 VEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIA 187
Score = 62.1 bits (144), Expect = 4e-09
Identities = 44/159 (27%), Positives = 71/159 (44%)
Frame = +1
Query: 391 YGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKA 570
YG + ++E V+ G N SQ+G + + AP+ + L ++
Sbjct: 81 YGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQG--------IAPVQVCTNLLIKQVVE 132
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
VA G H++ L V+ G N GQ G N+ + L + +V + C
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNC----LHIKRVVGIAC 188
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
GQ S+ + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 58.8 bits (136), Expect = 3e-08
Identities = 47/180 (26%), Positives = 81/180 (45%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG ++A E VF G N Q+G S N P ++ ++I
Sbjct: 130 VVEVACGSHHSMALAADGE---VFAWGYNNCGQVGSGSTA-NQPTPRKVTNC-LHIK--- 181
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ ++ + D VY G N GQ G N N+ + + L
Sbjct: 182 ---RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-----LTPVRVAALHSV 233
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ + CG H+L +T+ G +YA G GQ G GN +N +P ++ + E++V++A+
Sbjct: 234 CVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIM--VEKERVVEIAA 291
>AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein.
Length = 531
Score = 62.1 bits (144), Expect = 4e-09
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGV-YTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
+IK+++ G ++L+ ++GV Y G+N Y Q G N+ V N+ L K+ +
Sbjct: 75 KIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTT-NQGIAPVQVCTNL--LIKQ-V 130
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
V+V CG HS+ + G+V+A G+ GQ G G+ N+ TP V + +++V +A
Sbjct: 131 VEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIA 187
Score = 62.1 bits (144), Expect = 4e-09
Identities = 44/159 (27%), Positives = 71/159 (44%)
Frame = +1
Query: 391 YGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKA 570
YG + ++E V+ G N SQ+G + + AP+ + L ++
Sbjct: 81 YGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQG--------IAPVQVCTNLLIKQVVE 132
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
VA G H++ L V+ G N GQ G N+ + L + +V + C
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNC----LHIKRVVGIAC 188
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
GQ S+ + ++G+VY G+ +GQ GLGN N+ TP V
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRV 227
Score = 58.8 bits (136), Expect = 3e-08
Identities = 47/180 (26%), Positives = 81/180 (45%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +ACG ++A E VF G N Q+G S N P ++ ++I
Sbjct: 130 VVEVACGSHHSMALAADGE---VFAWGYNNCGQVGSGSTA-NQPTPRKVTNC-LHIK--- 181
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
+ +A G+ ++ + D VY G N GQ G N N+ + + L
Sbjct: 182 ---RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-----LTPVRVAALHSV 233
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
+ + CG H+L +T+ G +YA G GQ G GN +N +P ++ + E++V++A+
Sbjct: 234 CVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIM--VEKERVVEIAA 291
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 61.7 bits (143), Expect = 5e-09
Identities = 39/117 (33%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ A+G H+++L V + G+N+ GQ GR+ E + IQ L + IV
Sbjct: 24 ELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGE-----LPEPIQAL-ETLIV 77
Query: 739 D-VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
D V CG++HSL + G+V+A G G++GQ G+G + S I + KI++V+
Sbjct: 78 DLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVS 134
Score = 54.4 bits (125), Expect = 7e-07
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Frame = +1
Query: 430 HKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI-KAVAAGRAHTIILT 606
H+V G N+ Q+G +R E P ++LE I V+ G+ H++ +
Sbjct: 42 HRVLSCGDNSRGQLGRRGAQRGELPE----------PIQALETLIVDLVSCGKEHSLAVC 91
Query: 607 DKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESG 786
K V+ G + GQ G + E + S I L I+ V CG HSL +++
Sbjct: 92 HKGRVFAWGAGSEGQLG----IGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 787 KVYACGWGADGQTGLG-NYDNRSTPTAV 867
+V++ G + GQ GLG + ++++P V
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRV 175
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/217 (26%), Positives = 89/217 (41%), Gaps = 4/217 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
RV+ WG G LGI + + P + I ++CG+ ++A
Sbjct: 95 RVFAWGAGSEGQLGI------------GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLA 142
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE-CEIKAVAAGR 585
K S+ VF G N+ Q+G E +P + +SLE + VAAG
Sbjct: 143 LSKDSQ---VFSWGKNSHGQLGLGK-------EFPSQASPQRV--RSLEGIPLAQVAAGG 190
Query: 586 AHTIILTDKEGVYTLGNNAYGQC---GRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQ 756
AH+ L+ + G+N+ GQ GR V V S+ ++ LG +V + CG
Sbjct: 191 AHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGA--LKNLG---VVYISCGD 245
Query: 757 DHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
H+ +T+ GKV+ G GQ G + P V
Sbjct: 246 AHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLV 282
>AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein.
Length = 322
Score = 61.7 bits (143), Expect = 5e-09
Identities = 39/117 (33%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ A+G H+++L V + G+N+ GQ GR+ E + IQ L + IV
Sbjct: 24 ELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGE-----LPEPIQAL-ETLIV 77
Query: 739 D-VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
D V CG++HSL + G+V+A G G++GQ G+G + S I + KI++V+
Sbjct: 78 DLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVS 134
Score = 54.4 bits (125), Expect = 7e-07
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Frame = +1
Query: 430 HKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI-KAVAAGRAHTIILT 606
H+V G N+ Q+G +R E P ++LE I V+ G+ H++ +
Sbjct: 42 HRVLSCGDNSRGQLGRRGAQRGELPE----------PIQALETLIVDLVSCGKEHSLAVC 91
Query: 607 DKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESG 786
K V+ G + GQ G + E + S I L I+ V CG HSL +++
Sbjct: 92 HKGRVFAWGAGSEGQLG----IGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 787 KVYACGWGADGQTGLG-NYDNRSTPTAV 867
+V++ G + GQ GLG + ++++P V
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRV 175
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/217 (26%), Positives = 89/217 (41%), Gaps = 4/217 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
RV+ WG G LGI + + P + I ++CG+ ++A
Sbjct: 95 RVFAWGAGSEGQLGI------------GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLA 142
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE-CEIKAVAAGR 585
K S+ VF G N+ Q+G E +P + +SLE + VAAG
Sbjct: 143 LSKDSQ---VFSWGKNSHGQLGLGK-------EFPSQASPQRV--RSLEGIPLAQVAAGG 190
Query: 586 AHTIILTDKEGVYTLGNNAYGQC---GRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQ 756
AH+ L+ + G+N+ GQ GR V V S+ ++ LG +V + CG
Sbjct: 191 AHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGA--LKNLG---VVYISCGD 245
Query: 757 DHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
H+ +T+ GKV+ G GQ G + P V
Sbjct: 246 AHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLV 282
>AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein.
Length = 364
Score = 61.7 bits (143), Expect = 5e-09
Identities = 39/117 (33%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ A+G H+++L V + G+N+ GQ GR+ E + IQ L + IV
Sbjct: 24 ELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGE-----LPEPIQAL-ETLIV 77
Query: 739 D-VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
D V CG++HSL + G+V+A G G++GQ G+G + S I + KI++V+
Sbjct: 78 DLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVS 134
Score = 54.4 bits (125), Expect = 7e-07
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Frame = +1
Query: 430 HKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI-KAVAAGRAHTIILT 606
H+V G N+ Q+G +R E P ++LE I V+ G+ H++ +
Sbjct: 42 HRVLSCGDNSRGQLGRRGAQRGELPE----------PIQALETLIVDLVSCGKEHSLAVC 91
Query: 607 DKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESG 786
K V+ G + GQ G + E + S I L I+ V CG HSL +++
Sbjct: 92 HKGRVFAWGAGSEGQLG----IGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 787 KVYACGWGADGQTGLG-NYDNRSTPTAV 867
+V++ G + GQ GLG + ++++P V
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRV 175
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/217 (26%), Positives = 89/217 (41%), Gaps = 4/217 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
RV+ WG G LGI + + P + I ++CG+ ++A
Sbjct: 95 RVFAWGAGSEGQLGI------------GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLA 142
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE-CEIKAVAAGR 585
K S+ VF G N+ Q+G E +P + +SLE + VAAG
Sbjct: 143 LSKDSQ---VFSWGKNSHGQLGLGK-------EFPSQASPQRV--RSLEGIPLAQVAAGG 190
Query: 586 AHTIILTDKEGVYTLGNNAYGQC---GRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQ 756
AH+ L+ + G+N+ GQ GR V V S+ ++ LG +V + CG
Sbjct: 191 AHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGA--LKNLG---VVYISCGD 245
Query: 757 DHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
H+ +T+ GKV+ G GQ G + P V
Sbjct: 246 AHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLV 282
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 61.7 bits (143), Expect = 5e-09
Identities = 39/117 (33%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ A+G H+++L V + G+N+ GQ GR+ E + IQ L + IV
Sbjct: 24 ELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGE-----LPEPIQAL-ETLIV 77
Query: 739 D-VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
D V CG++HSL + G+V+A G G++GQ G+G + S I + KI++V+
Sbjct: 78 DLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVS 134
Score = 54.4 bits (125), Expect = 7e-07
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Frame = +1
Query: 430 HKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI-KAVAAGRAHTIILT 606
H+V G N+ Q+G +R E P ++LE I V+ G+ H++ +
Sbjct: 42 HRVLSCGDNSRGQLGRRGAQRGELPE----------PIQALETLIVDLVSCGKEHSLAVC 91
Query: 607 DKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESG 786
K V+ G + GQ G + E + S I L I+ V CG HSL +++
Sbjct: 92 HKGRVFAWGAGSEGQLG----IGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 787 KVYACGWGADGQTGLG-NYDNRSTPTAV 867
+V++ G + GQ GLG + ++++P V
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRV 175
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/217 (26%), Positives = 89/217 (41%), Gaps = 4/217 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
RV+ WG G LGI + + P + I ++CG+ ++A
Sbjct: 95 RVFAWGAGSEGQLGI------------GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLA 142
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE-CEIKAVAAGR 585
K S+ VF G N+ Q+G E +P + +SLE + VAAG
Sbjct: 143 LSKDSQ---VFSWGKNSHGQLGLGK-------EFPSQASPQRV--RSLEGIPLAQVAAGG 190
Query: 586 AHTIILTDKEGVYTLGNNAYGQC---GRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQ 756
AH+ L+ + G+N+ GQ GR V V S+ ++ LG +V + CG
Sbjct: 191 AHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGA--LKNLG---VVYISCGD 245
Query: 757 DHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
H+ +T+ GKV+ G GQ G + P V
Sbjct: 246 AHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLV 282
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 61.7 bits (143), Expect = 5e-09
Identities = 39/117 (33%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ A+G H+++L V + G+N+ GQ GR+ E + IQ L + IV
Sbjct: 24 ELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGE-----LPEPIQAL-ETLIV 77
Query: 739 D-VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
D V CG++HSL + G+V+A G G++GQ G+G + S I + KI++V+
Sbjct: 78 DLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVS 134
Score = 54.4 bits (125), Expect = 7e-07
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Frame = +1
Query: 430 HKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI-KAVAAGRAHTIILT 606
H+V G N+ Q+G +R E P ++LE I V+ G+ H++ +
Sbjct: 42 HRVLSCGDNSRGQLGRRGAQRGELPE----------PIQALETLIVDLVSCGKEHSLAVC 91
Query: 607 DKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESG 786
K V+ G + GQ G + E + S I L I+ V CG HSL +++
Sbjct: 92 HKGRVFAWGAGSEGQLG----IGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 787 KVYACGWGADGQTGLG-NYDNRSTPTAV 867
+V++ G + GQ GLG + ++++P V
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRV 175
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/217 (26%), Positives = 89/217 (41%), Gaps = 4/217 (1%)
Frame = +1
Query: 229 RVYVWGFAETGALGIHLPRXXXXXXXXXXXXXLVWHPMRSSFAERFDITNIACGYGFTVA 408
RV+ WG G LGI + + P + I ++CG+ ++A
Sbjct: 95 RVFAWGAGSEGQLGI------------GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLA 142
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLE-CEIKAVAAGR 585
K S+ VF G N+ Q+G E +P + +SLE + VAAG
Sbjct: 143 LSKDSQ---VFSWGKNSHGQLGLGK-------EFPSQASPQRV--RSLEGIPLAQVAAGG 190
Query: 586 AHTIILTDKEGVYTLGNNAYGQC---GRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQ 756
AH+ L+ + G+N+ GQ GR V V S+ ++ LG +V + CG
Sbjct: 191 AHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGA--LKNLG---VVYISCGD 245
Query: 757 DHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
H+ +T+ GKV+ G GQ G + P V
Sbjct: 246 AHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLV 282
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 56.0 bits (129), Expect = 2e-07
Identities = 58/199 (29%), Positives = 84/199 (42%), Gaps = 4/199 (2%)
Frame = +1
Query: 337 PMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLL 516
P R + E + I +ACG T+A FG G +G +S ++ P ++ +
Sbjct: 4177 PERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLG-NSTAKSSPQKIDV 4235
Query: 517 SYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSM 696
IK VA G ++ LT VYT G + R + + E G
Sbjct: 4236 LCG----------IGIKKVACGTQFSVALTKDGHVYTFGQD------RLIGLPE---GRA 4276
Query: 697 VTHN----IQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTA 864
HN I L I DV G +H+L + +G VYA G ++GQ GLG+ ++ PT
Sbjct: 4277 RNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTL 4336
Query: 865 VIGDITTEKIVKVASTGDC 921
V G K V+ S G C
Sbjct: 4337 VTG--LQGKNVRQISAGRC 4353
Score = 54.8 bits (126), Expect = 6e-07
Identities = 30/93 (32%), Positives = 48/93 (51%)
Frame = +1
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H++ LT+ V++ G+ YG+ G N + + + I+ L E +V + CG HS
Sbjct: 4093 HSMALTESGEVFSWGDGDYGKLGHG-NSDRQRR----PRQIEALQGEEVVQMSCGFKHSA 4147
Query: 769 FITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
+T GK++ G G G+ GLGN N+ P V
Sbjct: 4148 VVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERV 4180
Score = 52.8 bits (121), Expect = 2e-06
Identities = 32/110 (29%), Positives = 60/110 (54%)
Frame = +1
Query: 538 PYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQK 717
P++S++ ++ + HT+ T + V++ G+ YG+ G + ++Y ++ +Q
Sbjct: 453 PHRSIK-KVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYP-KLIQGPLQ- 509
Query: 718 LGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
GK +V V G HS +TE G++Y G G G+ G G+ ++R+ PT V
Sbjct: 510 -GKV-VVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLV 557
Score = 52.8 bits (121), Expect = 2e-06
Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 2/175 (1%)
Frame = +1
Query: 349 SFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGY-HSPRRNHPLELLLSYA 525
S + F +T + G S+ +E +VF G ++G+ +S R+ P ++
Sbjct: 4074 SALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQG 4133
Query: 526 PIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTH 705
E+ ++ G H+ ++T ++T GN YG+ G N++ +
Sbjct: 4134 E----------EVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKK-----LPE 4178
Query: 706 NIQKLGKENIVDVCCGQDHSLFITESGK-VYACGWGADGQTGLGNYDNRSTPTAV 867
+ L I V CG +H+L ++ G V+A G G G+ GLGN +S+P +
Sbjct: 4179 RVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKI 4233
Score = 48.4 bits (110), Expect = 5e-05
Identities = 40/157 (25%), Positives = 67/157 (42%)
Frame = +1
Query: 367 DITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYK 546
++ ++CG T+A K FG G N ++G+ R + +++ + ++I
Sbjct: 562 NVGEVSCGSSHTIALSKDGRTVWSFGGGDN--GKLGHGDTNRVYKPKVIEALQGMFI--- 616
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
+ V AG ++ LT VY G CG + ++ I++L
Sbjct: 617 ------RKVCAGSQSSLALTSTGQVYAWG------CGACLGCGSSEATALRPKLIEELAA 664
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGN 837
IVDV G H L ++ +VYA G + GQ G GN
Sbjct: 665 TRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGN 701
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/116 (25%), Positives = 56/116 (48%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
+ + V G+ T ++ V G +YG+ G+ +++ V +Q +V
Sbjct: 4028 QAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQ--GNSDDLHVLTVISALQGFVVTQLV 4085
Query: 739 DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
C HS+ +TESG+V++ G G G+ G GN D + P I + E++V+++
Sbjct: 4086 TSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQ-IEALQGEEVVQMS 4140
Score = 34.3 bits (75), Expect = 0.85
Identities = 16/35 (45%), Positives = 23/35 (65%)
Frame = +1
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRST 855
GQ + I+ G V ACG G+ G+ GLG+ +N+ST
Sbjct: 411 GQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQST 445
>BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein.
Length = 457
Score = 55.6 bits (128), Expect = 3e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 562 IKAVAAGR--AHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ V +G AH++++T + +++ G N GQ G + + K I+ L E I
Sbjct: 85 VRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLG-----HGDTKRVEAPRLIEGLSHEVI 139
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGN 837
V CG++H+L +TE+G V+A G GQ GLGN
Sbjct: 140 VSAACGRNHTLALTETGSVFAFGENKMGQLGLGN 173
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/167 (25%), Positives = 68/167 (40%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLE 507
+W P R + + G S+ + + K++ G N Q+G+ +R
Sbjct: 71 LWGPHRYGCLAGVRVRTVVSG-SCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVE--- 126
Query: 508 LLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYK 687
AP I S E + A A GR HT+ LT+ V+ G N GQ G +
Sbjct: 127 -----APRLIEGLSHEVIVSA-ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPS 180
Query: 688 GSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTG 828
+ + +N Q + K + CG + S+ + G +Y+ G GQ G
Sbjct: 181 PAQIMYNGQPITK-----MACGAEFSMIMDCKGNLYSFGCPEYGQLG 222
Score = 41.9 bits (94), Expect = 0.004
Identities = 48/185 (25%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I + ACG T+A +T VF G N Q+G + P +P I Y
Sbjct: 139 IVSAACGRNHTLALTETGS---VFAFGENKMGQLGLGNQTDAVP-------SPAQIMYNG 188
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-------VNEEYKGSMVTHN 708
I +A G ++I+ K +Y+ G YGQ G + EY +V
Sbjct: 189 QP--ITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 246
Query: 709 I----------QKLGKENIV--DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS 852
+ Q L N+V DV CG +H+L + +V++ G+G G+ G +
Sbjct: 247 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEM 306
Query: 853 TPTAV 867
P V
Sbjct: 307 VPRLV 311
Score = 31.5 bits (68), Expect = 6.0
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +1
Query: 760 HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
HSL IT GK+++ G GQ G G+ P + G ++ E IV A
Sbjct: 96 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEG-LSHEVIVSAA 143
>BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein.
Length = 522
Score = 55.6 bits (128), Expect = 3e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 562 IKAVAAGR--AHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ V +G AH++++T + +++ G N GQ G + + K I+ L E I
Sbjct: 150 VRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLG-----HGDTKRVEAPRLIEGLSHEVI 204
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGN 837
V CG++H+L +TE+G V+A G GQ GLGN
Sbjct: 205 VSAACGRNHTLALTETGSVFAFGENKMGQLGLGN 238
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/167 (25%), Positives = 68/167 (40%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLE 507
+W P R + + G S+ + + K++ G N Q+G+ +R
Sbjct: 136 LWGPHRYGCLAGVRVRTVVSG-SCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVE--- 191
Query: 508 LLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYK 687
AP I S E + A A GR HT+ LT+ V+ G N GQ G +
Sbjct: 192 -----APRLIEGLSHEVIVSA-ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPS 245
Query: 688 GSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTG 828
+ + +N Q + K + CG + S+ + G +Y+ G GQ G
Sbjct: 246 PAQIMYNGQPITK-----MACGAEFSMIMDCKGNLYSFGCPEYGQLG 287
Score = 41.9 bits (94), Expect = 0.004
Identities = 48/185 (25%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I + ACG T+A +T VF G N Q+G + P +P I Y
Sbjct: 204 IVSAACGRNHTLALTETGS---VFAFGENKMGQLGLGNQTDAVP-------SPAQIMYNG 253
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-------VNEEYKGSMVTHN 708
I +A G ++I+ K +Y+ G YGQ G + EY +V
Sbjct: 254 QP--ITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 311
Query: 709 I----------QKLGKENIV--DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS 852
+ Q L N+V DV CG +H+L + +V++ G+G G+ G +
Sbjct: 312 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEM 371
Query: 853 TPTAV 867
P V
Sbjct: 372 VPRLV 376
Score = 31.5 bits (68), Expect = 6.0
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +1
Query: 760 HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
HSL IT GK+++ G GQ G G+ P + G ++ E IV A
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEG-LSHEVIVSAA 208
>BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome
condensation 2 protein.
Length = 522
Score = 55.6 bits (128), Expect = 3e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 562 IKAVAAGR--AHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ V +G AH++++T + +++ G N GQ G + + K I+ L E I
Sbjct: 150 VRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLG-----HGDTKRVEAPRLIEGLSHEVI 204
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGN 837
V CG++H+L +TE+G V+A G GQ GLGN
Sbjct: 205 VSAACGRNHTLALTETGSVFAFGENKMGQLGLGN 238
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/167 (25%), Positives = 68/167 (40%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLE 507
+W P R + + G S+ + + K++ G N Q+G+ +R
Sbjct: 136 LWGPHRYGCLAGVRVRTVVSG-SCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVE--- 191
Query: 508 LLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYK 687
AP I S E + A A GR HT+ LT+ V+ G N GQ G +
Sbjct: 192 -----APRLIEGLSHEVIVSA-ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPS 245
Query: 688 GSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTG 828
+ + +N Q + K + CG + S+ + G +Y+ G GQ G
Sbjct: 246 PAQIMYNGQPITK-----MACGAEFSMIMDCKGNLYSFGCPEYGQLG 287
Score = 41.9 bits (94), Expect = 0.004
Identities = 48/185 (25%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I + ACG T+A +T VF G N Q+G + P +P I Y
Sbjct: 204 IVSAACGRNHTLALTETGS---VFAFGENKMGQLGLGNQTDAVP-------SPAQIMYNG 253
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-------VNEEYKGSMVTHN 708
I +A G ++I+ K +Y+ G YGQ G + EY +V
Sbjct: 254 QP--ITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 311
Query: 709 I----------QKLGKENIV--DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS 852
+ Q L N+V DV CG +H+L + +V++ G+G G+ G +
Sbjct: 312 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEM 371
Query: 853 TPTAV 867
P V
Sbjct: 372 VPRLV 376
Score = 31.5 bits (68), Expect = 6.0
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +1
Query: 760 HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
HSL IT GK+++ G GQ G G+ P + G ++ E IV A
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEG-LSHEVIVSAA 208
>AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 55.6 bits (128), Expect = 3e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 562 IKAVAAGR--AHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ V +G AH++++T + +++ G N GQ G + + K I+ L E I
Sbjct: 6 VRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLG-----HGDTKRVEAPRLIEGLSHEVI 60
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGN 837
V CG++H+L +TE+G V+A G GQ GLGN
Sbjct: 61 VSAACGRNHTLALTETGSVFAFGENKMGQLGLGN 94
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/140 (27%), Positives = 61/140 (43%)
Frame = +1
Query: 409 SIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRA 588
S+ + + K++ G N Q+G+ +R AP I S E + A A GR
Sbjct: 18 SLLITTEGKLWSWGRNEKGQLGHGDTKRVE--------APRLIEGLSHEVIVSA-ACGRN 68
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
HT+ LT+ V+ G N GQ G + + + +N Q + K + CG + S+
Sbjct: 69 HTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITK-----MACGAEFSM 123
Query: 769 FITESGKVYACGWGADGQTG 828
+ G +Y+ G GQ G
Sbjct: 124 IMDCKGNLYSFGCPEYGQLG 143
Score = 41.9 bits (94), Expect = 0.004
Identities = 48/185 (25%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I + ACG T+A +T VF G N Q+G + P +P I Y
Sbjct: 60 IVSAACGRNHTLALTETGS---VFAFGENKMGQLGLGNQTDAVP-------SPAQIMYNG 109
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-------VNEEYKGSMVTHN 708
I +A G ++I+ K +Y+ G YGQ G + EY +V
Sbjct: 110 QP--ITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 167
Query: 709 I----------QKLGKENIV--DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS 852
+ Q L N+V DV CG +H+L + +V++ G+G G+ G +
Sbjct: 168 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEM 227
Query: 853 TPTAV 867
P V
Sbjct: 228 VPRLV 232
Score = 31.5 bits (68), Expect = 6.0
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +1
Query: 760 HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
HSL IT GK+++ G GQ G G+ P + G ++ E IV A
Sbjct: 17 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEG-LSHEVIVSAA 64
>AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein.
Length = 522
Score = 55.6 bits (128), Expect = 3e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 562 IKAVAAGR--AHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ V +G AH++++T + +++ G N GQ G + + K I+ L E I
Sbjct: 150 VRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLG-----HGDTKRVEAPRLIEGLSHEVI 204
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGN 837
V CG++H+L +TE+G V+A G GQ GLGN
Sbjct: 205 VSAACGRNHTLALTETGSVFAFGENKMGQLGLGN 238
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/167 (25%), Positives = 68/167 (40%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLE 507
+W P R + + G S+ + + K++ G N Q+G+ +R
Sbjct: 136 LWGPHRYGCLAGVRVRTVVSG-SCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVE--- 191
Query: 508 LLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYK 687
AP I S E + A A GR HT+ LT+ V+ G N GQ G +
Sbjct: 192 -----APRLIEGLSHEVIVSA-ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPS 245
Query: 688 GSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTG 828
+ + +N Q + K + CG + S+ + G +Y+ G GQ G
Sbjct: 246 PAQIMYNGQPITK-----MACGAEFSMIMDCKGNLYSFGCPEYGQLG 287
Score = 41.9 bits (94), Expect = 0.004
Identities = 48/185 (25%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I + ACG T+A +T VF G N Q+G + P +P I Y
Sbjct: 204 IVSAACGRNHTLALTETGS---VFAFGENKMGQLGLGNQTDAVP-------SPAQIMYNG 253
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-------VNEEYKGSMVTHN 708
I +A G ++I+ K +Y+ G YGQ G + EY +V
Sbjct: 254 QP--ITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 311
Query: 709 I----------QKLGKENIV--DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS 852
+ Q L N+V DV CG +H+L + +V++ G+G G+ G +
Sbjct: 312 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEM 371
Query: 853 TPTAV 867
P V
Sbjct: 372 VPRLV 376
Score = 31.5 bits (68), Expect = 6.0
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +1
Query: 760 HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
HSL IT GK+++ G GQ G G+ P + G ++ E IV A
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEG-LSHEVIVSAA 208
>AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein.
Length = 564
Score = 55.6 bits (128), Expect = 3e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 562 IKAVAAGR--AHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENI 735
++ V +G AH++++T + +++ G N GQ G + + K I+ L E I
Sbjct: 192 VRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLG-----HGDTKRVEAPRLIEGLSHEVI 246
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGN 837
V CG++H+L +TE+G V+A G GQ GLGN
Sbjct: 247 VSAACGRNHTLALTETGSVFAFGENKMGQLGLGN 280
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/167 (25%), Positives = 68/167 (40%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLE 507
+W P R + + G S+ + + K++ G N Q+G+ +R
Sbjct: 178 LWGPHRYGCLAGVRVRTVVSG-SCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVE--- 233
Query: 508 LLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYK 687
AP I S E + A A GR HT+ LT+ V+ G N GQ G +
Sbjct: 234 -----APRLIEGLSHEVIVSA-ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPS 287
Query: 688 GSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTG 828
+ + +N Q + K + CG + S+ + G +Y+ G GQ G
Sbjct: 288 PAQIMYNGQPITK-----MACGAEFSMIMDCKGNLYSFGCPEYGQLG 329
Score = 41.9 bits (94), Expect = 0.004
Identities = 48/185 (25%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I + ACG T+A +T VF G N Q+G + P +P I Y
Sbjct: 246 IVSAACGRNHTLALTETGS---VFAFGENKMGQLGLGNQTDAVP-------SPAQIMYNG 295
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-------VNEEYKGSMVTHN 708
I +A G ++I+ K +Y+ G YGQ G + EY +V
Sbjct: 296 QP--ITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 353
Query: 709 I----------QKLGKENIV--DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS 852
+ Q L N+V DV CG +H+L + +V++ G+G G+ G +
Sbjct: 354 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEM 413
Query: 853 TPTAV 867
P V
Sbjct: 414 VPRLV 418
Score = 31.5 bits (68), Expect = 6.0
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +1
Query: 760 HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
HSL IT GK+++ G GQ G G+ P + G ++ E IV A
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEG-LSHEVIVSAA 250
>AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein.
Length = 409
Score = 55.2 bits (127), Expect = 4e-07
Identities = 37/114 (32%), Positives = 58/114 (50%)
Frame = +1
Query: 568 AVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVC 747
A +G A T+ LTD + V++ G+ YG+ GR + G V I L +V V
Sbjct: 53 ACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGS-----DGCKVPMKIDSLTGLGVVKVE 107
Query: 748 CGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
CG S+ +T+SG VY G G + G G+ D+ P V G + +K++ +A+
Sbjct: 108 CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQG-LQGKKVIAIAT 160
Score = 47.2 bits (107), Expect = 1e-04
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Frame = +1
Query: 574 AAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCG 753
AAG AH+ +T +YT G YG+ G + ++ K +V + L +VD+ CG
Sbjct: 1 AAGGAHSACVTAAGDLYTWGKGRYGRLGHS-DSEDQLKPKLV----EALQGHRVVDIACG 55
Query: 754 QD--HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKV 903
+L +T+ V++ G G G+ G G D P I +T +VKV
Sbjct: 56 SGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMK-IDSLTGLGVVKV 106
Score = 38.7 bits (86), Expect = 0.039
Identities = 28/112 (25%), Positives = 48/112 (42%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
V G ++ LT VYT G Y + G + + +Q L + ++ +
Sbjct: 106 VECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRP-----RQVQGLQGKKVIAIAT 160
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
G H + TE G+VY G +GQ G G + P ++ + +K+ +VA
Sbjct: 161 GSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRP-RLVAALQGKKVNRVA 211
Score = 31.1 bits (67), Expect = 7.9
Identities = 21/70 (30%), Positives = 32/70 (45%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
++ A+A G H + T+ VYT G+N GQ G N + +V L + +
Sbjct: 154 KVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLG-DGTTNAIQRPRLVA----ALQGKKVN 208
Query: 739 DVCCGQDHSL 768
V CG H+L
Sbjct: 209 RVACGSAHTL 218
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 55.2 bits (127), Expect = 4e-07
Identities = 32/135 (23%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
Frame = +1
Query: 517 SYAPIYIPYKSL--ECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKG 690
+Y+ ++ ++S+ E +I + G H++ L+ ++ G N +GQ G V ++
Sbjct: 123 NYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLG----VGRKFPS 178
Query: 691 SMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVI 870
+ ++ L + + G+ HS+ ++ SG +Y+ G GQ GLG+ +++ P+ +
Sbjct: 179 TTTPQIVEHLAGVPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIE 238
Query: 871 GDITTEKIVKVASTG 915
G + +K+ VA G
Sbjct: 239 G-LDNQKVEFVACGG 252
Score = 52.4 bits (120), Expect = 3e-06
Identities = 31/104 (29%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
+++ VA G +H+ +LT ++T G +GQ G NE + +V +L +
Sbjct: 244 KVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNE-LRPCLVA----ELVGYRVT 298
Query: 739 DVCCGQDHSL-FITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
+ CG+ H+L ++++ GKV++ G G DGQ G G ++ P V
Sbjct: 299 QIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPV 342
Score = 51.2 bits (117), Expect = 7e-06
Identities = 45/191 (23%), Positives = 81/191 (42%)
Frame = +1
Query: 334 HPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELL 513
H S + I I CG ++A K E +F G N Q+G R P
Sbjct: 128 HLRFESILQEKKIIQITCGDYHSLALSKGGE---LFAWGQNLHGQLGVG---RKFPS--- 178
Query: 514 LSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
+ P + + + + ++AG AH++ L+ +Y+ G N GQ G +++
Sbjct: 179 -TTTPQIVEHLA-GVPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSL 236
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
I+ L + + V CG HS +T+ G ++ G G GQ G + N P ++
Sbjct: 237 -----IEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRP-CLVA 290
Query: 874 DITTEKIVKVA 906
++ ++ ++A
Sbjct: 291 ELVGYRVTQIA 301
Score = 34.3 bits (75), Expect = 0.85
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +1
Query: 364 FDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPR-RNHPLELLLSYA-PIYI 537
+ +T IACG T+A + S+ KVF G D Q+G R + PL + +S + + +
Sbjct: 295 YRVTQIACGRWHTLAYV--SDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKL 352
Query: 538 PYKSLECEIKAVAAGRAHTIILTDKEGVY 624
+ E E+ +A G ++ KE Y
Sbjct: 353 ESHTSEKELIMIAGGNQSILLWIKKENSY 381
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/180 (25%), Positives = 87/180 (48%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
+ +IACG ++ A E + +G G ++G H + + +L++ K
Sbjct: 553 VVHIACGSTYSAAITAEGELY-TWGRG--NYGRLG-HGSSEDEAIPMLVA------GLKG 602
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
L+ A +G A T+ +T+ V++ G+ YG+ GR + G I+KL
Sbjct: 603 LKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGS-----DGCKTPKLIEKLQDL 657
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
++V V CG S+ +T+ G+VY+ G G + + G G ++ P + G + +K++ VA+
Sbjct: 658 DVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEG-LQGKKVIDVAA 716
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/186 (24%), Positives = 82/186 (44%)
Frame = +1
Query: 349 SFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAP 528
SF+E N+ G + + + + KV+ G T+ ++G P+ ++
Sbjct: 2984 SFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALS 3043
Query: 529 IYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHN 708
Y+ K AV +G H LT V++ G G+ G +N + K +
Sbjct: 3044 SYVVKKV------AVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCD-KPRL---- 3092
Query: 709 IQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTE 888
I+ L + I D+ CG HS +T SG++Y G G G+ G G+ + P ++ +
Sbjct: 3093 IEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKP-KMVKVLLGH 3151
Query: 889 KIVKVA 906
++++VA
Sbjct: 3152 RVIQVA 3157
Score = 52.0 bits (119), Expect = 4e-06
Identities = 45/179 (25%), Positives = 87/179 (48%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I +IACG + A + E ++ G+ ++G+ ++ +L + + ++
Sbjct: 3101 IRDIACGSSHSAALTSSGE---LYTWGLGEYGRLGHG----DNTTQLKPKMVKVLLGHRV 3153
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
++ A + A T+ LTD+ V++ G+ +G+ GR + +G + NI++L +
Sbjct: 3154 IQV---ACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGS-----EGCNIPQNIERLNGQ 3205
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
+ + CG SL +T+SG V+ G G + G G+ + P V G + +KIV VA
Sbjct: 3206 GVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEG-LRGKKIVHVA 3263
Score = 50.4 bits (115), Expect = 1e-05
Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 2/117 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ VAAG AH+ +T +YT G YG+ G + ++ K +V + L +V
Sbjct: 4092 EVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHS-DSEDQLKPKLV----EALQGHRVV 4146
Query: 739 DVCCGQD--HSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKV 903
D+ CG +L +T+ V++ G G G+ G G D P I +T +VKV
Sbjct: 4147 DIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMK-IDSLTGLGVVKV 4202
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/112 (33%), Positives = 54/112 (48%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
+ G ++ LT V+T G Y + G +V+ + V ++ GK+ IV V
Sbjct: 3210 IECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH--VRKPQVVEGLR--GKK-IVHVAV 3264
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
G H L +T+SG+VYA G GQ G G PT V G + +KI +VA
Sbjct: 3265 GALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQG-LEGQKITRVA 3315
Score = 41.1 bits (92), Expect = 0.007
Identities = 23/53 (43%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Frame = +1
Query: 751 GQDHSLF-ITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
G + +LF +T GK+YA G+GA G+ G+G ++ STPT ++ I I KVA
Sbjct: 3992 GGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPT-LLESIQHVFIKKVA 4043
Score = 38.7 bits (86), Expect = 0.039
Identities = 28/112 (25%), Positives = 48/112 (42%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
V G ++ LT VYT G Y + G + + +Q L + ++ +
Sbjct: 4202 VECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRP-----RQVQGLQGKKVIAIAT 4256
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
G H + TE G+VY G +GQ G G + P ++ + +K+ +VA
Sbjct: 4257 GSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRP-RLVAALQGKKVNRVA 4307
Score = 37.1 bits (82), Expect = 0.12
Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGR-KVNVNEEYKGSMVTHNIQKLGKENI 735
+I VA G H + +TD VY G+N +GQ G VN K ++V Q L + I
Sbjct: 3258 KIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNR--KPTLV----QGLEGQKI 3311
Query: 736 VDVCCGQDHSL 768
V CG HS+
Sbjct: 3312 TRVACGSSHSV 3322
Score = 37.1 bits (82), Expect = 0.12
Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Frame = +1
Query: 580 GRAHTIILTDKEG-VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQ 756
G T+ +G +Y G A G+ G + E + +IQ + + + V G
Sbjct: 3992 GGEQTLFAVTADGKLYATGYGAGGRLG--IGGTESVSTPTLLESIQHVFIKKVA-VNSGG 4048
Query: 757 DHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
H L ++ G+VY+ G DG+ G GN P VI + ++V VA+ G
Sbjct: 4049 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIESLRGIEVVDVAAGG 4100
Score = 34.7 bits (76), Expect = 0.64
Identities = 25/93 (26%), Positives = 43/93 (46%)
Frame = +1
Query: 544 KSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLG 723
K + ++ V G +I LT VY+ G + G E + + +Q G
Sbjct: 653 KLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGH--GTEEHVRYPKLLEGLQ--G 708
Query: 724 KENIVDVCCGQDHSLFITESGKVYACGWGADGQ 822
K+ ++DV G H L +TE +V++ WG++ Q
Sbjct: 709 KK-VIDVAAGSTHCLALTEDSEVHS--WGSNDQ 738
Score = 31.1 bits (67), Expect = 7.9
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Frame = +1
Query: 709 IQKLGKENIVDVCCGQD--HSLFITESGKVYACGWGADGQTGLGN 837
+Q L NIV + D H L + +G+VY+ G G G+ G G+
Sbjct: 487 VQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGD 531
Score = 31.1 bits (67), Expect = 7.9
Identities = 21/70 (30%), Positives = 32/70 (45%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
++ A+A G H + T+ VYT G+N GQ G N + +V L + +
Sbjct: 4250 KVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLG-DGTTNAIQRPRLVA----ALQGKKVN 4304
Query: 739 DVCCGQDHSL 768
V CG H+L
Sbjct: 4305 RVACGSAHTL 4314
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 52.8 bits (121), Expect = 2e-06
Identities = 43/124 (34%), Positives = 58/124 (46%), Gaps = 4/124 (3%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHN----IQKLGKE 729
IK VA G ++ LT VYT G + R + + E G HN I L
Sbjct: 31 IKKVACGTQFSVALTKDGHVYTFGQD------RLIGLPE---GRARNHNRPQQIPVLAGV 81
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVAS 909
I DV G +H+L + +G VYA G ++GQ GLG+ ++ PT V G K V+ S
Sbjct: 82 IIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTG--LQGKNVRQIS 139
Query: 910 TGDC 921
G C
Sbjct: 140 AGRC 143
>BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating
guanine nucleotide exchange factor protein.
Length = 458
Score = 52.4 bits (120), Expect = 3e-06
Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 1/142 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSL-ECEIKAVAAGRAHTIILTDK 612
+F G+N D Q+G H ++ P + P KSL C I+ VA G TI+LT+
Sbjct: 70 LFVCGLNKDGQLGL-----GHTEDI-----PYFTPCKSLFGCPIQQVACGWDFTIMLTEN 119
Query: 613 EGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKV 792
V + G+N++GQ G V + +V I+ L KE +V + G H++ T SG V
Sbjct: 120 GQVLSCGSNSFGQLG----VPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIV 174
Query: 793 YACGWGADGQTGLGNYDNRSTP 858
+ WG TGL + R P
Sbjct: 175 FQ--WG----TGLASCGRRLCP 190
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGY-HSPRRNHPLELLLSYAPIYIPYK 546
I +ACG+ FT I +E +V G N+ Q+G H PRR ++ A I + +
Sbjct: 103 IQQVACGWDFT---IMLTENGQVLSCGSNSFGQLGVPHGPRR-----CVVPQA-IELHKE 153
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL-G 723
+ C +AAG H + T V+ G CGR++ + ++ G
Sbjct: 154 KVVC----IAAGLRHAVAATASGIVFQWGTGL-ASCGRRLCPGQTLPLFFTAKEPSRVTG 208
Query: 724 KENIVDVC--CGQDHSLFITESGKVYACGWGADGQ 822
EN +C G DHS +T++G+VY G GQ
Sbjct: 209 LENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQ 243
Score = 46.4 bits (105), Expect = 2e-04
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
++ + G H+ ++TD ++ G N GQ G + Y + L I
Sbjct: 51 VRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPC-----KSLFGCPIQQ 105
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS-TPTAVIGDITTEKIVKVAS 909
V CG D ++ +TE+G+V +CG + GQ G+ + R P A+ ++ EK+V +A+
Sbjct: 106 VACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAI--ELHKEKVVCIAA 160
Score = 41.5 bits (93), Expect = 0.006
Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-- 732
++ A+ +G H + T+ ++T G YGQ GRK+ E +K + N
Sbjct: 266 KVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSM 325
Query: 733 ---------IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITT 885
+V CG +H+L I G Y+ GW G G G N P V +++
Sbjct: 326 PSSPHCLTGATEVSCGSEHNLAII-GGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSS 384
Query: 886 EKIVKVASTGDCVXL 930
++ G + L
Sbjct: 385 SGLLVGCGAGHSLAL 399
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/76 (27%), Positives = 38/76 (50%)
Frame = +1
Query: 619 VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYA 798
++ G N+YGQ G + E+ ++ K ++ + G HS +T+ G ++
Sbjct: 17 LFAWGANSYGQLG--LGHKEDVLLPQQLNDFCK--PRSVRRITGGGGHSAVVTDGGDLFV 72
Query: 799 CGWGADGQTGLGNYDN 846
CG DGQ GLG+ ++
Sbjct: 73 CGLNKDGQLGLGHTED 88
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 52.4 bits (120), Expect = 3e-06
Identities = 31/104 (29%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
+++ VA G +H+ +LT ++T G +GQ G NE + +V +L +
Sbjct: 244 KVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNE-LRPCLVA----ELVGYRVT 298
Query: 739 DVCCGQDHSL-FITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
+ CG+ H+L ++++ GKV++ G G DGQ G G ++ P V
Sbjct: 299 QIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPV 342
Score = 50.4 bits (115), Expect = 1e-05
Identities = 45/191 (23%), Positives = 80/191 (41%)
Frame = +1
Query: 334 HPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELL 513
H S + I I CG ++A K E +F G N Q+G R P
Sbjct: 128 HLRFESILQEKKIIQITCGDYHSLALSKGGE---LFAWGQNLHGQLGVG---RKFPS--- 178
Query: 514 LSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGS 693
+ P + + + + ++AG AH+ L+ +Y+ G N GQ G +++
Sbjct: 179 -TTTPQIVEHLA-GVPLAQISAGEAHSTALSMSGNIYSWGKNECGQLGLGHTESKDDPSL 236
Query: 694 MVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
I+ L + + V CG HS +T+ G ++ G G GQ G + N P ++
Sbjct: 237 -----IEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRP-CLVA 290
Query: 874 DITTEKIVKVA 906
++ ++ ++A
Sbjct: 291 ELVGYRVTQIA 301
Score = 34.3 bits (75), Expect = 0.85
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +1
Query: 364 FDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPR-RNHPLELLLSYA-PIYI 537
+ +T IACG T+A + S+ KVF G D Q+G R + PL + +S + + +
Sbjct: 295 YRVTQIACGRWHTLAYV--SDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKL 352
Query: 538 PYKSLECEIKAVAAGRAHTIILTDKEGVY 624
+ E E+ +A G ++ KE Y
Sbjct: 353 ESHTSEKELIMIAGGNQSILLWIKKENSY 381
>AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 288
Score = 52.4 bits (120), Expect = 3e-06
Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 1/142 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSL-ECEIKAVAAGRAHTIILTDK 612
+F G+N D Q+G H ++ P + P KSL C I+ VA G TI+LT+
Sbjct: 70 LFVCGLNKDGQLGL-----GHTEDI-----PYFTPCKSLFGCPIQQVACGWDFTIMLTEN 119
Query: 613 EGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKV 792
V + G+N++GQ G V + +V I+ L KE +V + G H++ T SG V
Sbjct: 120 GQVLSCGSNSFGQLG----VPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIV 174
Query: 793 YACGWGADGQTGLGNYDNRSTP 858
+ WG TGL + R P
Sbjct: 175 FQ--WG----TGLASCGRRLCP 190
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGY-HSPRRNHPLELLLSYAPIYIPYK 546
I +ACG+ FT I +E +V G N+ Q+G H PRR ++ A I + +
Sbjct: 103 IQQVACGWDFT---IMLTENGQVLSCGSNSFGQLGVPHGPRR-----CVVPQA-IELHKE 153
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL-G 723
+ C +AAG H + T V+ G CGR++ + ++ G
Sbjct: 154 KVVC----IAAGLRHAVAATASGIVFQWGTGL-ASCGRRLCPGQTLPLFFTAKEPSRVTG 208
Query: 724 KENIVDVC--CGQDHSLFITESGKVYACGWGADGQ 822
EN +C G DHS +T++G+VY G GQ
Sbjct: 209 LENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQ 243
Score = 46.4 bits (105), Expect = 2e-04
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
++ + G H+ ++TD ++ G N GQ G + Y + L I
Sbjct: 51 VRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPC-----KSLFGCPIQQ 105
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS-TPTAVIGDITTEKIVKVAS 909
V CG D ++ +TE+G+V +CG + GQ G+ + R P A+ ++ EK+V +A+
Sbjct: 106 VACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAI--ELHKEKVVCIAA 160
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/76 (27%), Positives = 38/76 (50%)
Frame = +1
Query: 619 VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYA 798
++ G N+YGQ G + E+ ++ K ++ + G HS +T+ G ++
Sbjct: 17 LFAWGANSYGQLG--LGHKEDVLLPQQLNDFCK--PRSVRRITGGGGHSAVVTDGGDLFV 72
Query: 799 CGWGADGQTGLGNYDN 846
CG DGQ GLG+ ++
Sbjct: 73 CGLNKDGQLGLGHTED 88
>AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 458
Score = 52.4 bits (120), Expect = 3e-06
Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 1/142 (0%)
Frame = +1
Query: 436 VFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSL-ECEIKAVAAGRAHTIILTDK 612
+F G+N D Q+G H ++ P + P KSL C I+ VA G TI+LT+
Sbjct: 70 LFVCGLNKDGQLGL-----GHTEDI-----PYFTPCKSLFGCPIQQVACGWDFTIMLTEN 119
Query: 613 EGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKV 792
V + G+N++GQ G V + +V I+ L KE +V + G H++ T SG V
Sbjct: 120 GQVLSCGSNSFGQLG----VPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIV 174
Query: 793 YACGWGADGQTGLGNYDNRSTP 858
+ WG TGL + R P
Sbjct: 175 FQ--WG----TGLASCGRRLCP 190
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGY-HSPRRNHPLELLLSYAPIYIPYK 546
I +ACG+ FT I +E +V G N+ Q+G H PRR ++ A I + +
Sbjct: 103 IQQVACGWDFT---IMLTENGQVLSCGSNSFGQLGVPHGPRR-----CVVPQA-IELHKE 153
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKL-G 723
+ C +AAG H + T V+ G CGR++ + ++ G
Sbjct: 154 KVVC----IAAGLRHAVAATASGIVFQWGTGL-ASCGRRLCPGQTLPLFFTAKEPSRVTG 208
Query: 724 KENIVDVC--CGQDHSLFITESGKVYACGWGADGQ 822
EN +C G DHS +T++G+VY G GQ
Sbjct: 209 LENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQ 243
Score = 46.4 bits (105), Expect = 2e-04
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
++ + G H+ ++TD ++ G N GQ G + Y + L I
Sbjct: 51 VRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPC-----KSLFGCPIQQ 105
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS-TPTAVIGDITTEKIVKVAS 909
V CG D ++ +TE+G+V +CG + GQ G+ + R P A+ ++ EK+V +A+
Sbjct: 106 VACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAI--ELHKEKVVCIAA 160
Score = 41.5 bits (93), Expect = 0.006
Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-- 732
++ A+ +G H + T+ ++T G YGQ GRK+ E +K + N
Sbjct: 266 KVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSM 325
Query: 733 ---------IVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITT 885
+V CG +H+L I G Y+ GW G G G N P V +++
Sbjct: 326 PSSPHCLTGATEVSCGSEHNLAII-GGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSS 384
Query: 886 EKIVKVASTGDCVXL 930
++ G + L
Sbjct: 385 SGLLVGCGAGHSLAL 399
Score = 37.5 bits (83), Expect = 0.091
Identities = 21/76 (27%), Positives = 38/76 (50%)
Frame = +1
Query: 619 VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYA 798
++ G N+YGQ G + E+ ++ K ++ + G HS +T+ G ++
Sbjct: 17 LFAWGANSYGQLG--LGHKEDVLLPQQLNDFCK--PRSVRRITGGGGHSAVVTDGGDLFV 72
Query: 799 CGWGADGQTGLGNYDN 846
CG DGQ GLG+ ++
Sbjct: 73 CGLNKDGQLGLGHTED 88
>AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein.
Length = 328
Score = 52.0 bits (119), Expect = 4e-06
Identities = 45/179 (25%), Positives = 87/179 (48%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I +IACG + A + E ++ G+ ++G+ ++ +L + + ++
Sbjct: 139 IRDIACGSSHSAALTSSGE---LYTWGLGEYGRLGHG----DNTTQLKPKMVKVLLGHRV 191
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
++ A + A T+ LTD+ V++ G+ +G+ GR + +G + NI++L +
Sbjct: 192 IQV---ACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGS-----EGCNIPQNIERLNGQ 243
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
+ + CG SL +T+SG V+ G G + G G+ + P V G + +KIV VA
Sbjct: 244 GVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEG-LRGKKIVHVA 301
Score = 51.6 bits (118), Expect = 5e-06
Identities = 45/186 (24%), Positives = 81/186 (43%)
Frame = +1
Query: 349 SFAERFDITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAP 528
SF+E N+ G + + + + KV+ G T+ ++G P+ ++
Sbjct: 22 SFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALS 81
Query: 529 IYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHN 708
Y+ K AV +G H LT V+ G G+ G +N + K +
Sbjct: 82 SYVVKKV------AVHSGGRHATALTVDGKVFWWGEGDDGKLGHFSRMNCD-KPRL---- 130
Query: 709 IQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTE 888
I+ L + I D+ CG HS +T SG++Y G G G+ G G+ + P ++ +
Sbjct: 131 IEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKP-KMVKVLLGH 189
Query: 889 KIVKVA 906
++++VA
Sbjct: 190 RVIQVA 195
Score = 37.9 bits (84), Expect = 0.069
Identities = 28/86 (32%), Positives = 42/86 (48%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
+ G ++ LT V+T G Y + G +V+ + V ++ GK+ IV V
Sbjct: 248 IECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH--VRKPQVVEGLR--GKK-IVHVAV 302
Query: 751 GQDHSLFITESGKVYACGWGADGQTG 828
G H L +T+SG+VYA G GQ G
Sbjct: 303 GALHCLAVTDSGQVYAWGDNDHGQQG 328
>X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein.
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
tyrosine kinase-beta protein.
Length = 1196
Score = 50.4 bits (115), Expect = 1e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +1
Query: 415 KTSEQHKVFGTGINTDSQIGYHSPRRNHPLEL--LLSYAPIYIPYKSLECEIKAVAAGRA 588
K ++ V+ G NT+ +G+ S H EL L S + IYI K V +
Sbjct: 137 KNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYI---------KQVVLCKF 187
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H++ L+ K VYT G+ G+ G + + + +V ++ L N V +DH++
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLG-----HGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTV 242
Query: 769 FITESGKVYACGWGADGQTGL 831
+TE G VY G Q G+
Sbjct: 243 VLTEDGCVYTFGLNIFHQLGI 263
Score = 39.9 bits (89), Expect = 0.017
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +1
Query: 604 TDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITES 783
TD VYT G+N G + N ++ +V ++ I V + HS+F+++
Sbjct: 139 TDPTDVYTWGDNTNFTLGHG-SQNSKHHPELV--DLFSRSGIYIKQVVLCKFHSVFLSQK 195
Query: 784 GKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
G+VY CG G G+ G G+ P V G
Sbjct: 196 GQVYTCGHGPGGRLGHGDEQTCLVPRLVEG 225
Score = 35.5 bits (78), Expect = 0.37
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQK--LGKENIVDV 744
VAA + HT++LT+ VYT G N + Q G + V IQ L I+ V
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLG----IIPPPSSCNVPRQIQAKYLKGRTIIGV 289
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTG 828
G+ H++ T VY G GQ G
Sbjct: 290 AAGRFHTVLWTREA-VYTMGLNG-GQLG 315
Score = 34.7 bits (76), Expect = 0.64
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV- 738
I VAAGR HT++ T +E VYT+G N GQ G ++ N E K + L ++I
Sbjct: 286 IIGVAAGRFHTVLWT-REAVYTMGLNG-GQLGCLLDPNGE-KCVTAPRQVSALHHKDIAL 342
Query: 739 -DVCCGQDHSLFITESGKVY 795
V ++ +T G +Y
Sbjct: 343 SLVAASDGATVCVTTRGDIY 362
>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
tyrosine kinase-alpha protein.
Length = 1353
Score = 50.4 bits (115), Expect = 1e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +1
Query: 415 KTSEQHKVFGTGINTDSQIGYHSPRRNHPLEL--LLSYAPIYIPYKSLECEIKAVAAGRA 588
K ++ V+ G NT+ +G+ S H EL L S + IYI K V +
Sbjct: 137 KNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYI---------KQVVLCKF 187
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H++ L+ K VYT G+ G+ G + + + +V ++ L N V +DH++
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLG-----HGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTV 242
Query: 769 FITESGKVYACGWGADGQTGL 831
+TE G VY G Q G+
Sbjct: 243 VLTEDGCVYTFGLNIFHQLGI 263
Score = 39.9 bits (89), Expect = 0.017
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +1
Query: 604 TDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITES 783
TD VYT G+N G + N ++ +V ++ I V + HS+F+++
Sbjct: 139 TDPTDVYTWGDNTNFTLGHG-SQNSKHHPELV--DLFSRSGIYIKQVVLCKFHSVFLSQK 195
Query: 784 GKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
G+VY CG G G+ G G+ P V G
Sbjct: 196 GQVYTCGHGPGGRLGHGDEQTCLVPRLVEG 225
Score = 35.5 bits (78), Expect = 0.37
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQK--LGKENIVDV 744
VAA + HT++LT+ VYT G N + Q G + V IQ L I+ V
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLG----IIPPPSSCNVPRQIQAKYLKGRTIIGV 289
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTG 828
G+ H++ T VY G GQ G
Sbjct: 290 AAGRFHTVLWTREA-VYTMGLNG-GQLG 315
Score = 34.7 bits (76), Expect = 0.64
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV- 738
I VAAGR HT++ T +E VYT+G N GQ G ++ N E K + L ++I
Sbjct: 286 IIGVAAGRFHTVLWT-REAVYTMGLNG-GQLGCLLDPNGE-KCVTAPRQVSALHHKDIAL 342
Query: 739 -DVCCGQDHSLFITESGKVY 795
V ++ +T G +Y
Sbjct: 343 SLVAASDGATVCVTTRGDIY 362
>CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein.
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 50.4 bits (115), Expect = 1e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +1
Query: 415 KTSEQHKVFGTGINTDSQIGYHSPRRNHPLEL--LLSYAPIYIPYKSLECEIKAVAAGRA 588
K ++ V+ G NT+ +G+ S H EL L S + IYI K V +
Sbjct: 137 KNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYI---------KQVVLCKF 187
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H++ L+ K VYT G+ G+ G + + + +V ++ L N V +DH++
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLG-----HGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTV 242
Query: 769 FITESGKVYACGWGADGQTGL 831
+TE G VY G Q G+
Sbjct: 243 VLTEDGCVYTFGLNIFHQLGI 263
Score = 39.9 bits (89), Expect = 0.017
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +1
Query: 604 TDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITES 783
TD VYT G+N G + N ++ +V ++ I V + HS+F+++
Sbjct: 139 TDPTDVYTWGDNTNFTLGHG-SQNSKHHPELV--DLFSRSGIYIKQVVLCKFHSVFLSQK 195
Query: 784 GKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
G+VY CG G G+ G G+ P V G
Sbjct: 196 GQVYTCGHGPGGRLGHGDEQTCLVPRLVEG 225
Score = 35.5 bits (78), Expect = 0.37
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQK--LGKENIVDV 744
VAA + HT++LT+ VYT G N + Q G + V IQ L I+ V
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLG----IIPPPSSCNVPRQIQAKYLKGRTIIGV 289
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTG 828
G+ H++ T VY G GQ G
Sbjct: 290 AAGRFHTVLWTREA-VYTMGLNG-GQLG 315
Score = 34.7 bits (76), Expect = 0.64
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV- 738
I VAAGR HT++ T +E VYT+G N GQ G ++ N E K + L ++I
Sbjct: 286 IIGVAAGRFHTVLWT-REAVYTMGLNG-GQLGCLLDPNGE-KCVTAPRQVSALHHKDIAL 342
Query: 739 -DVCCGQDHSLFITESGKVY 795
V ++ +T G +Y
Sbjct: 343 SLVAASDGATVCVTTRGDIY 362
>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 50.4 bits (115), Expect = 1e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +1
Query: 415 KTSEQHKVFGTGINTDSQIGYHSPRRNHPLEL--LLSYAPIYIPYKSLECEIKAVAAGRA 588
K ++ V+ G NT+ +G+ S H EL L S + IYI K V +
Sbjct: 137 KNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYI---------KQVVLCKF 187
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H++ L+ K VYT G+ G+ G + + + +V ++ L N V +DH++
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLG-----HGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTV 242
Query: 769 FITESGKVYACGWGADGQTGL 831
+TE G VY G Q G+
Sbjct: 243 VLTEDGCVYTFGLNIFHQLGI 263
Score = 39.9 bits (89), Expect = 0.017
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +1
Query: 604 TDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITES 783
TD VYT G+N G + N ++ +V ++ I V + HS+F+++
Sbjct: 139 TDPTDVYTWGDNTNFTLGHG-SQNSKHHPELV--DLFSRSGIYIKQVVLCKFHSVFLSQK 195
Query: 784 GKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
G+VY CG G G+ G G+ P V G
Sbjct: 196 GQVYTCGHGPGGRLGHGDEQTCLVPRLVEG 225
Score = 35.5 bits (78), Expect = 0.37
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQK--LGKENIVDV 744
VAA + HT++LT+ VYT G N + Q G + V IQ L I+ V
Sbjct: 234 VAAAKDHTVVLTEDGCVYTFGLNIFHQLG----IIPPPSSCNVPRQIQAKYLKGRTIIGV 289
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTG 828
G+ H++ T VY G GQ G
Sbjct: 290 AAGRFHTVLWTREA-VYTMGLNG-GQLG 315
Score = 34.7 bits (76), Expect = 0.64
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV- 738
I VAAGR HT++ T +E VYT+G N GQ G ++ N E K + L ++I
Sbjct: 286 IIGVAAGRFHTVLWT-REAVYTMGLNG-GQLGCLLDPNGE-KCVTAPRQVSALHHKDIAL 342
Query: 739 -DVCCGQDHSLFITESGKVY 795
V ++ +T G +Y
Sbjct: 343 SLVAASDGATVCVTTRGDIY 362
>BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 452
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 278 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 327
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 328 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 381
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 382 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 438
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 95 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 149
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 150 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 209
Query: 907 STGD 918
S D
Sbjct: 210 SGND 213
>BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
Length = 1187
Score = 50.4 bits (115), Expect = 1e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +1
Query: 415 KTSEQHKVFGTGINTDSQIGYHSPRRNHPLEL--LLSYAPIYIPYKSLECEIKAVAAGRA 588
K ++ V+ G NT+ +G+ S H EL L S + IYI K V +
Sbjct: 133 KNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYI---------KQVVLCKF 183
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H++ L+ K VYT G+ G+ G + + + +V ++ L N V +DH++
Sbjct: 184 HSVFLSQKGQVYTCGHGPGGRLG-----HGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTV 238
Query: 769 FITESGKVYACGWGADGQTGL 831
+TE G VY G Q G+
Sbjct: 239 VLTEDGCVYTFGLNIFHQLGI 259
Score = 39.9 bits (89), Expect = 0.017
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +1
Query: 604 TDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITES 783
TD VYT G+N G + N ++ +V ++ I V + HS+F+++
Sbjct: 135 TDPTDVYTWGDNTNFTLGHG-SQNSKHHPELV--DLFSRSGIYIKQVVLCKFHSVFLSQK 191
Query: 784 GKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
G+VY CG G G+ G G+ P V G
Sbjct: 192 GQVYTCGHGPGGRLGHGDEQTCLVPRLVEG 221
Score = 35.5 bits (78), Expect = 0.37
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQK--LGKENIVDV 744
VAA + HT++LT+ VYT G N + Q G + V IQ L I+ V
Sbjct: 230 VAAAKDHTVVLTEDGCVYTFGLNIFHQLG----IIPPPSSCNVPRQIQAKYLKGRTIIGV 285
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTG 828
G+ H++ T VY G GQ G
Sbjct: 286 AAGRFHTVLWTREA-VYTMGLNG-GQLG 311
Score = 34.7 bits (76), Expect = 0.64
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV- 738
I VAAGR HT++ T +E VYT+G N GQ G ++ N E K + L ++I
Sbjct: 282 IIGVAAGRFHTVLWT-REAVYTMGLNG-GQLGCLLDPNGE-KCVTAPRQVSALHHKDIAL 338
Query: 739 -DVCCGQDHSLFITESGKVY 795
V ++ +T G +Y
Sbjct: 339 SLVAASDGATVCVTTRGDIY 358
>AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/177 (23%), Positives = 75/177 (42%)
Frame = +1
Query: 385 CGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKSLECEI 564
CG FT A S + V+G G++ Q+G + L S+ K+
Sbjct: 247 CGAYFTFA---ISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSF-------KNSTKSW 296
Query: 565 KAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
+ G+ HT+ + + Y+LG YG+ G E+ ++++ + V
Sbjct: 297 VGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR------LPAVSSV 350
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
CG +T+ G+V+A G G + Q G G ++ +P ++G ++V S+G
Sbjct: 351 ACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
S+ ++ AG HT+ L+ VY+ G N G GR +V +GS + +L +
Sbjct: 64 SIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSV----EGSEMVPGKVEL-Q 118
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
E +V V G H+ +T+ G+V+ G D +G + + +VKVA
Sbjct: 119 EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVA 178
Query: 907 STGD 918
S D
Sbjct: 179 SGND 182
>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
Length = 1379
Score = 50.4 bits (115), Expect = 1e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +1
Query: 415 KTSEQHKVFGTGINTDSQIGYHSPRRNHPLEL--LLSYAPIYIPYKSLECEIKAVAAGRA 588
K ++ V+ G NT+ +G+ S H EL L S + IYI K V +
Sbjct: 163 KNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYI---------KQVVLCKF 213
Query: 589 HTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSL 768
H++ L+ K VYT G+ G+ G + + + +V ++ L N V +DH++
Sbjct: 214 HSVFLSQKGQVYTCGHGPGGRLG-----HGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTV 268
Query: 769 FITESGKVYACGWGADGQTGL 831
+TE G VY G Q G+
Sbjct: 269 VLTEDGCVYTFGLNIFHQLGI 289
Score = 39.9 bits (89), Expect = 0.017
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +1
Query: 604 TDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITES 783
TD VYT G+N G + N ++ +V ++ I V + HS+F+++
Sbjct: 165 TDPTDVYTWGDNTNFTLGHG-SQNSKHHPELV--DLFSRSGIYIKQVVLCKFHSVFLSQK 221
Query: 784 GKVYACGWGADGQTGLGNYDNRSTPTAVIG 873
G+VY CG G G+ G G+ P V G
Sbjct: 222 GQVYTCGHGPGGRLGHGDEQTCLVPRLVEG 251
Score = 35.5 bits (78), Expect = 0.37
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQK--LGKENIVDV 744
VAA + HT++LT+ VYT G N + Q G + V IQ L I+ V
Sbjct: 260 VAAAKDHTVVLTEDGCVYTFGLNIFHQLG----IIPPPSSCNVPRQIQAKYLKGRTIIGV 315
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTG 828
G+ H++ T VY G GQ G
Sbjct: 316 AAGRFHTVLWTREA-VYTMGLNG-GQLG 341
Score = 34.7 bits (76), Expect = 0.64
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV- 738
I VAAGR HT++ T +E VYT+G N GQ G ++ N E K + L ++I
Sbjct: 312 IIGVAAGRFHTVLWT-REAVYTMGLNG-GQLGCLLDPNGE-KCVTAPRQVSALHHKDIAL 368
Query: 739 -DVCCGQDHSLFITESGKVY 795
V ++ +T G +Y
Sbjct: 369 SLVAASDGATVCVTTRGDIY 388
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/154 (27%), Positives = 71/154 (46%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I ++CG FTV +++ +++ G + +G LE P+ + +
Sbjct: 428 IRQVSCGDDFTVC---VTDEGQLYAFGSDYYGCMGVDKVAGPEVLE------PMQLNF-F 477
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
L ++ V+ G H ++LT + VY+ G YG+ G ++ E+Y + L
Sbjct: 478 LSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG--LDSEEDYYTPQKVDVPKAL--- 532
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
IV V CG D + +T+SGKV ACG + GL
Sbjct: 533 IIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 566
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/118 (26%), Positives = 53/118 (44%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
I+ V+ G T+ +TD+ +Y G++ YG G E M + +
Sbjct: 428 IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPM---QLNFFLSNPVEQ 484
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V CG +H + +T + +VY+ G G G+ GL + ++ TP V D+ I+ G
Sbjct: 485 VSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKV--DVPKALIIVAVQCG 540
Score = 42.7 bits (96), Expect = 0.002
Identities = 52/209 (24%), Positives = 89/209 (42%), Gaps = 12/209 (5%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTG----INTDSQIGYHSPRRN 495
V PM+ +F + ++CG V + E + +G G + DS+ Y++P++
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYS-WGCGEYGRLGLDSEEDYYTPQK- 525
Query: 496 HPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-----QCGR 660
+ +P K+L I AV G T +LT V G N + QC
Sbjct: 526 -----------VDVP-KALI--IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMS 571
Query: 661 KVNVNEEYKGSMVTHNI---QKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ +E Y T + ++L I + G+ H+ I E G++ G GQ G+
Sbjct: 572 GIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGV 631
Query: 832 GNYDNRSTPTAVIGDITTEKIVKVASTGD 918
GNY R + G + +++++V S GD
Sbjct: 632 GNYKKRLGINLLGGPLGGKQVIRV-SCGD 659
Score = 39.9 bits (89), Expect = 0.017
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-QCGRKVNVNEEYKGSMVTHNIQKLGKEN 732
C + V AG H ++T ++ +YT N G + ++ ++ H ++KL +
Sbjct: 369 CSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKH-VEKLQGKA 427
Query: 733 IVDVCCGQDHSLFITESGKVYACG 804
I V CG D ++ +T+ G++YA G
Sbjct: 428 IRQVSCGDDFTVCVTDEGQLYAFG 451
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/154 (27%), Positives = 71/154 (46%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I ++CG FTV +++ +++ G + +G LE P+ + +
Sbjct: 428 IRQVSCGDDFTVC---VTDEGQLYAFGSDYYGCMGVDKVAGPEVLE------PMQLNF-F 477
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
L ++ V+ G H ++LT + VY+ G YG+ G ++ E+Y + L
Sbjct: 478 LSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG--LDSEEDYYTPQKVDVPKAL--- 532
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
IV V CG D + +T+SGKV ACG + GL
Sbjct: 533 IIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 566
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/118 (26%), Positives = 53/118 (44%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
I+ V+ G T+ +TD+ +Y G++ YG G E M + +
Sbjct: 428 IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPM---QLNFFLSNPVEQ 484
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V CG +H + +T + +VY+ G G G+ GL + ++ TP V D+ I+ G
Sbjct: 485 VSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKV--DVPKALIIVAVQCG 540
Score = 42.7 bits (96), Expect = 0.002
Identities = 52/209 (24%), Positives = 89/209 (42%), Gaps = 12/209 (5%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTG----INTDSQIGYHSPRRN 495
V PM+ +F + ++CG V + E + +G G + DS+ Y++P++
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYS-WGCGEYGRLGLDSEEDYYTPQK- 525
Query: 496 HPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-----QCGR 660
+ +P K+L I AV G T +LT V G N + QC
Sbjct: 526 -----------VDVP-KALI--IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMS 571
Query: 661 KVNVNEEYKGSMVTHNI---QKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ +E Y T + ++L I + G+ H+ I E G++ G GQ G+
Sbjct: 572 GIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGV 631
Query: 832 GNYDNRSTPTAVIGDITTEKIVKVASTGD 918
GNY R + G + +++++V S GD
Sbjct: 632 GNYKKRLGINLLGGPLGGKQVIRV-SCGD 659
Score = 39.9 bits (89), Expect = 0.017
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-QCGRKVNVNEEYKGSMVTHNIQKLGKEN 732
C + V AG H ++T ++ +YT N G + ++ ++ H ++KL +
Sbjct: 369 CSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKH-VEKLQGKA 427
Query: 733 IVDVCCGQDHSLFITESGKVYACG 804
I V CG D ++ +T+ G++YA G
Sbjct: 428 IRQVSCGDDFTVCVTDEGQLYAFG 451
>AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 414
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/154 (27%), Positives = 71/154 (46%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I ++CG FTV +++ +++ G + +G LE P+ + +
Sbjct: 98 IRQVSCGDDFTVC---VTDEGQLYAFGSDYYGCMGVDKVAGPEVLE------PMQLNF-F 147
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
L ++ V+ G H ++LT + VY+ G YG+ G ++ E+Y + L
Sbjct: 148 LSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG--LDSEEDYYTPQKVDVPKAL--- 202
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
IV V CG D + +T+SGKV ACG + GL
Sbjct: 203 IIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 236
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/118 (26%), Positives = 53/118 (44%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
I+ V+ G T+ +TD+ +Y G++ YG G E M + +
Sbjct: 98 IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPM---QLNFFLSNPVEQ 154
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V CG +H + +T + +VY+ G G G+ GL + ++ TP V D+ I+ G
Sbjct: 155 VSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKV--DVPKALIIVAVQCG 210
Score = 42.7 bits (96), Expect = 0.002
Identities = 52/209 (24%), Positives = 89/209 (42%), Gaps = 12/209 (5%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTG----INTDSQIGYHSPRRN 495
V PM+ +F + ++CG V + E + +G G + DS+ Y++P++
Sbjct: 138 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYS-WGCGEYGRLGLDSEEDYYTPQK- 195
Query: 496 HPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-----QCGR 660
+ +P K+L I AV G T +LT V G N + QC
Sbjct: 196 -----------VDVP-KALI--IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMS 241
Query: 661 KVNVNEEYKGSMVTHNI---QKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ +E Y T + ++L I + G+ H+ I E G++ G GQ G+
Sbjct: 242 GIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGV 301
Query: 832 GNYDNRSTPTAVIGDITTEKIVKVASTGD 918
GNY R + G + +++++V S GD
Sbjct: 302 GNYKKRLGINLLGGPLGGKQVIRV-SCGD 329
Score = 39.9 bits (89), Expect = 0.017
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-QCGRKVNVNEEYKGSMVTHNIQKLGKEN 732
C + V AG H ++T ++ +YT N G + ++ ++ H ++KL +
Sbjct: 39 CSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKH-VEKLQGKA 97
Query: 733 IVDVCCGQDHSLFITESGKVYACG 804
I V CG D ++ +T+ G++YA G
Sbjct: 98 IRQVSCGDDFTVCVTDEGQLYAFG 121
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/154 (27%), Positives = 71/154 (46%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I ++CG FTV +++ +++ G + +G LE P+ + +
Sbjct: 428 IHQVSCGDDFTVC---VTDEGQLYAFGSDYYGCMGVDKVAGPEVLE------PMQLNF-F 477
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
L ++ V+ G H ++LT + VY+ G YG+ G ++ E+Y + L
Sbjct: 478 LSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG--LDSEEDYYTPQKVDVPKAL--- 532
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
IV V CG D + +T+SGKV ACG + GL
Sbjct: 533 IIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 566
Score = 45.2 bits (102), Expect = 5e-04
Identities = 31/118 (26%), Positives = 52/118 (44%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
I V+ G T+ +TD+ +Y G++ YG G E M + +
Sbjct: 428 IHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPM---QLNFFLSNPVEQ 484
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V CG +H + +T + +VY+ G G G+ GL + ++ TP V D+ I+ G
Sbjct: 485 VSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKV--DVPKALIIVAVQCG 540
Score = 42.7 bits (96), Expect = 0.002
Identities = 52/209 (24%), Positives = 89/209 (42%), Gaps = 12/209 (5%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTG----INTDSQIGYHSPRRN 495
V PM+ +F + ++CG V + E + +G G + DS+ Y++P++
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYS-WGCGEYGRLGLDSEEDYYTPQK- 525
Query: 496 HPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-----QCGR 660
+ +P K+L I AV G T +LT V G N + QC
Sbjct: 526 -----------VDVP-KALI--IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMS 571
Query: 661 KVNVNEEYKGSMVTHNI---QKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ +E Y T + ++L I + G+ H+ I E G++ G GQ G+
Sbjct: 572 GIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGV 631
Query: 832 GNYDNRSTPTAVIGDITTEKIVKVASTGD 918
GNY R + G + +++++V S GD
Sbjct: 632 GNYKKRLGINLLGGPLGGKQVIRV-SCGD 659
Score = 39.9 bits (89), Expect = 0.017
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-QCGRKVNVNEEYKGSMVTHNIQKLGKEN 732
C + V AG H ++T ++ +YT N G + ++ ++ H ++KL +
Sbjct: 369 CSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKH-VEKLQGKA 427
Query: 733 IVDVCCGQDHSLFITESGKVYACG 804
I V CG D ++ +T+ G++YA G
Sbjct: 428 IHQVSCGDDFTVCVTDEGQLYAFG 451
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/154 (27%), Positives = 71/154 (46%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I ++CG FTV +++ +++ G + +G LE P+ + +
Sbjct: 428 IHQVSCGDDFTVC---VTDEGQLYAFGSDYYGCMGVDKVAGPEVLE------PMQLNF-F 477
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
L ++ V+ G H ++LT + VY+ G YG+ G ++ E+Y + L
Sbjct: 478 LSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG--LDSEEDYYTPQKVDVPKAL--- 532
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
IV V CG D + +T+SGKV ACG + GL
Sbjct: 533 IIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 566
Score = 45.2 bits (102), Expect = 5e-04
Identities = 31/118 (26%), Positives = 52/118 (44%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
I V+ G T+ +TD+ +Y G++ YG G E M + +
Sbjct: 428 IHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPM---QLNFFLSNPVEQ 484
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V CG +H + +T + +VY+ G G G+ GL + ++ TP V D+ I+ G
Sbjct: 485 VSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKV--DVPKALIIVAVQCG 540
Score = 42.7 bits (96), Expect = 0.002
Identities = 52/209 (24%), Positives = 89/209 (42%), Gaps = 12/209 (5%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTG----INTDSQIGYHSPRRN 495
V PM+ +F + ++CG V + E + +G G + DS+ Y++P++
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYS-WGCGEYGRLGLDSEEDYYTPQK- 525
Query: 496 HPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-----QCGR 660
+ +P K+L I AV G T +LT V G N + QC
Sbjct: 526 -----------VDVP-KALI--IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMS 571
Query: 661 KVNVNEEYKGSMVTHNI---QKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ +E Y T + ++L I + G+ H+ I E G++ G GQ G+
Sbjct: 572 GIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGV 631
Query: 832 GNYDNRSTPTAVIGDITTEKIVKVASTGD 918
GNY R + G + +++++V S GD
Sbjct: 632 GNYKKRLGINLLGGPLGGKQVIRV-SCGD 659
Score = 39.9 bits (89), Expect = 0.017
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-QCGRKVNVNEEYKGSMVTHNIQKLGKEN 732
C + V AG H ++T ++ +YT N G + ++ ++ H ++KL +
Sbjct: 369 CSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKH-VEKLQGKA 427
Query: 733 IVDVCCGQDHSLFITESGKVYACG 804
I V CG D ++ +T+ G++YA G
Sbjct: 428 IHQVSCGDDFTVCVTDEGQLYAFG 451
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/154 (27%), Positives = 71/154 (46%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I ++CG FTV +++ +++ G + +G LE P+ + +
Sbjct: 460 IHQVSCGDDFTVC---VTDEGQLYAFGSDYYGCMGVDKVAGPEVLE------PMQLNF-F 509
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKE 729
L ++ V+ G H ++LT + VY+ G YG+ G ++ E+Y + L
Sbjct: 510 LSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG--LDSEEDYYTPQKVDVPKAL--- 564
Query: 730 NIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
IV V CG D + +T+SGKV ACG + GL
Sbjct: 565 IIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 598
Score = 45.2 bits (102), Expect = 5e-04
Identities = 31/118 (26%), Positives = 52/118 (44%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
I V+ G T+ +TD+ +Y G++ YG G E M + +
Sbjct: 460 IHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPM---QLNFFLSNPVEQ 516
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V CG +H + +T + +VY+ G G G+ GL + ++ TP V D+ I+ G
Sbjct: 517 VSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKV--DVPKALIIVAVQCG 572
Score = 42.7 bits (96), Expect = 0.002
Identities = 52/209 (24%), Positives = 89/209 (42%), Gaps = 12/209 (5%)
Frame = +1
Query: 328 VWHPMRSSFAERFDITNIACGYGFTVASIKTSEQHKVFGTG----INTDSQIGYHSPRRN 495
V PM+ +F + ++CG V + E + +G G + DS+ Y++P++
Sbjct: 500 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYS-WGCGEYGRLGLDSEEDYYTPQK- 557
Query: 496 HPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-----QCGR 660
+ +P K+L I AV G T +LT V G N + QC
Sbjct: 558 -----------VDVP-KALI--IVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMS 603
Query: 661 KVNVNEEYKGSMVTHNI---QKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ +E Y T + ++L I + G+ H+ I E G++ G GQ G+
Sbjct: 604 GIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGV 663
Query: 832 GNYDNRSTPTAVIGDITTEKIVKVASTGD 918
GNY R + G + +++++V S GD
Sbjct: 664 GNYKKRLGINLLGGPLGGKQVIRV-SCGD 691
Score = 39.9 bits (89), Expect = 0.017
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 556 CEIKAVAAGRAHTIILTDKEGVYTLGNNAYG-QCGRKVNVNEEYKGSMVTHNIQKLGKEN 732
C + V AG H ++T ++ +YT N G + ++ ++ H ++KL +
Sbjct: 401 CSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKH-VEKLQGKA 459
Query: 733 IVDVCCGQDHSLFITESGKVYACG 804
I V CG D ++ +T+ G++YA G
Sbjct: 460 IHQVSCGDDFTVCVTDEGQLYAFG 483
>AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ35084 fis, clone PLACE6005482. ).
Length = 184
Score = 47.2 bits (107), Expect = 1e-04
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 4/170 (2%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I ++CG+ ++A K S+ VF G N+ Q+G E +P + +S
Sbjct: 8 IIQVSCGHYHSLALSKDSQ---VFSWGKNSHGQLGLGK-------EFPSQASPQRV--RS 55
Query: 550 LE-CEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQC---GRKVNVNEEYKGSMVTHNIQK 717
LE + VAAG AH+ L+ + G+N+ GQ GR V V S+ ++
Sbjct: 56 LEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGA--LKN 113
Query: 718 LGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
LG +V + CG H+ +T+ GKV+ G GQ G + P V
Sbjct: 114 LG---VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLV 160
Score = 38.7 bits (86), Expect = 0.039
Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Frame = +1
Query: 553 ECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN 732
+ +I V+ G H++ L+ V++ G N++GQ G + +E+ ++ L
Sbjct: 5 DIKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLG----LGKEFPSQASPQRVRSLEGIP 60
Query: 733 IVDVCCGQDHSLFITESGKVYACGWGADGQTGLG--NYDNRSTPTAVIGDITTEKIVKVA 906
+ V G HS ++ G + G + GQ L N +S +G + +V +
Sbjct: 61 LAQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYI- 119
Query: 907 STGD 918
S GD
Sbjct: 120 SCGD 123
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/102 (32%), Positives = 52/102 (50%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
IK VA G T LTD+ + T G+ + G G ++ + + ++V LG E +V
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHG-SLTDISQPTIVE---ALLGYE-MVQ 447
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V CG H L ++ +++A G G G+ GLG ++ S P V
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQV 489
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/92 (29%), Positives = 42/92 (45%)
Frame = +1
Query: 568 AVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVC 747
++ G AH+ +T YT G+N +GQ G +GS +Q L + V
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTR-----RGSRAPCKVQGLEGIKMAMVA 619
Query: 748 CGQDHSLFITESGKVYACGWGADGQTGLGNYD 843
CG ++ I +VY+ G GA G+ G + D
Sbjct: 620 CGDAFTVAIGAESEVYSWGKGARGRLGRRDED 651
Score = 33.1 bits (72), Expect = 2.0
Identities = 22/91 (24%), Positives = 38/91 (41%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ VA G +H + L+ + ++ G G+ G + E + + +
Sbjct: 444 EMVQVACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHS---CPQQVPMPPGQEAQ 498
Query: 739 DVCCGQDHSLFITESGKVYACGWGADGQTGL 831
V CG D S+ +T G+ ACG + GL
Sbjct: 499 RVVCGIDSSMILTVPGQALACGSNRFNKLGL 529
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/102 (32%), Positives = 52/102 (50%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
IK VA G T LTD+ + T G+ + G G ++ + + ++V LG E +V
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHG-SLTDISQPTIVE---ALLGYE-MVQ 447
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V CG H L ++ +++A G G G+ GLG ++ S P V
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQV 489
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/92 (29%), Positives = 42/92 (45%)
Frame = +1
Query: 568 AVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVC 747
++ G AH+ +T YT G+N +GQ G +GS +Q L + V
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTR-----RGSRAPCKVQGLEGIKMAMVA 619
Query: 748 CGQDHSLFITESGKVYACGWGADGQTGLGNYD 843
CG ++ I +VY+ G GA G+ G + D
Sbjct: 620 CGDAFTVAIGAESEVYSWGKGARGRLGRRDED 651
Score = 33.1 bits (72), Expect = 2.0
Identities = 22/91 (24%), Positives = 38/91 (41%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ VA G +H + L+ + ++ G G+ G + E + + +
Sbjct: 444 EMVQVACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHS---CPQQVPMPPGQEAQ 498
Query: 739 DVCCGQDHSLFITESGKVYACGWGADGQTGL 831
V CG D S+ +T G+ ACG + GL
Sbjct: 499 RVVCGIDSSMILTVPGQALACGSNRFNKLGL 529
>BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein.
Length = 812
Score = 46.4 bits (105), Expect = 2e-04
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 2/118 (1%)
Frame = +1
Query: 484 PRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQC--G 657
P R+ P+E+ S +PI + + + VA G H+ +TD Y G N+ GQC
Sbjct: 69 PWRSGPVEICPS-SPI-LENALVGQYVITVATGSFHSGAVTDNGVAYMCGENSAGQCAVA 126
Query: 658 RKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ V E S+ L I+ + CG++H+L ++ S +++A WG Q GL
Sbjct: 127 NQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWA--WGTGCQLGL 182
Score = 39.1 bits (87), Expect = 0.030
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-I 735
E+ + AG H++ LT K VY+ G+N +GQ G + ++ ++ + K+ EN +
Sbjct: 560 EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-----HSDFPTTV--PRLAKISSENGV 612
Query: 736 VDVCCGQDHSLFITES 783
+ G+D+SLF+ ++
Sbjct: 613 WSIAAGRDYSLFLVDT 628
>BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein.
Length = 351
Score = 46.4 bits (105), Expect = 2e-04
Identities = 27/72 (37%), Positives = 38/72 (52%)
Frame = +1
Query: 622 YTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYAC 801
++ G N GQ G + + K I+ L E IV CG++H+L +TE+G V+A
Sbjct: 1 WSWGRNEKGQLG-----HGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 55
Query: 802 GWGADGQTGLGN 837
G GQ GLGN
Sbjct: 56 GENKMGQLGLGN 67
Score = 44.0 bits (99), Expect = 0.001
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
I + A GR HT+ LT+ V+ G N GQ G + + + +N Q + K
Sbjct: 33 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITK----- 87
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTG 828
+ CG + S+ + G +Y+ G GQ G
Sbjct: 88 MACGAEFSMIMDCKGNLYSFGCPEYGQLG 116
Score = 41.9 bits (94), Expect = 0.004
Identities = 48/185 (25%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Frame = +1
Query: 370 ITNIACGYGFTVASIKTSEQHKVFGTGINTDSQIGYHSPRRNHPLELLLSYAPIYIPYKS 549
I + ACG T+A +T VF G N Q+G + P +P I Y
Sbjct: 33 IVSAACGRNHTLALTETGS---VFAFGENKMGQLGLGNQTDAVP-------SPAQIMYNG 82
Query: 550 LECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-------VNEEYKGSMVTHN 708
I +A G ++I+ K +Y+ G YGQ G + EY +V
Sbjct: 83 QP--ITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRR 140
Query: 709 I----------QKLGKENIV--DVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRS 852
+ Q L N+V DV CG +H+L + +V++ G+G G+ G +
Sbjct: 141 VAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEM 200
Query: 853 TPTAV 867
P V
Sbjct: 201 VPRLV 205
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/102 (32%), Positives = 52/102 (50%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
IK VA G T LTD+ + T G+ + G G ++ + + ++V LG E +V
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHG-SLTDISQPTIVE---ALLGYE-MVQ 447
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V CG H L ++ +++A G G G+ GLG ++ S P V
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQV 489
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/92 (29%), Positives = 42/92 (45%)
Frame = +1
Query: 568 AVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVC 747
++ G AH+ +T YT G+N +GQ G +GS +Q L + V
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTR-----RGSRAPCKVQGLEGIKMAMVA 619
Query: 748 CGQDHSLFITESGKVYACGWGADGQTGLGNYD 843
CG ++ I +VY+ G GA G+ G + D
Sbjct: 620 CGDAFTVAIGAESEVYSWGKGARGRLGRRDED 651
Score = 33.1 bits (72), Expect = 2.0
Identities = 22/91 (24%), Positives = 38/91 (41%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ VA G +H + L+ + ++ G G+ G + E + + +
Sbjct: 444 EMVQVACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHS---CPQQVPMPPGQEAQ 498
Query: 739 DVCCGQDHSLFITESGKVYACGWGADGQTGL 831
V CG D S+ +T G+ ACG + GL
Sbjct: 499 RVVCGIDSSMILTVPGQALACGSNRFNKLGL 529
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/102 (32%), Positives = 52/102 (50%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVD 741
IK VA G T LTD+ + T G+ + G G ++ + + ++V LG E +V
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHG-SLTDISQPTIVE---ALLGYE-MVQ 447
Query: 742 VCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V CG H L ++ +++A G G G+ GLG ++ S P V
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQV 489
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/92 (29%), Positives = 42/92 (45%)
Frame = +1
Query: 568 AVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVC 747
++ G AH+ +T YT G+N +GQ G +GS +Q L + V
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTR-----RGSRAPCKVQGLEGIKMAMVA 619
Query: 748 CGQDHSLFITESGKVYACGWGADGQTGLGNYD 843
CG ++ I +VY+ G GA G+ G + D
Sbjct: 620 CGDAFTVAIGAESEVYSWGKGARGRLGRRDED 651
Score = 33.1 bits (72), Expect = 2.0
Identities = 22/91 (24%), Positives = 38/91 (41%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIV 738
E+ VA G +H + L+ + ++ G G+ G + E + + +
Sbjct: 444 EMVQVACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHS---CPQQVPMPPGQEAQ 498
Query: 739 DVCCGQDHSLFITESGKVYACGWGADGQTGL 831
V CG D S+ +T G+ ACG + GL
Sbjct: 499 RVVCGIDSSMILTVPGQALACGSNRFNKLGL 529
>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
Length = 1237
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 2/118 (1%)
Frame = +1
Query: 484 PRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQC--G 657
P R+ P+E+ S +PI + + + VA G H+ +TD Y G N+ GQC
Sbjct: 69 PWRSGPVEICPS-SPI-LENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVA 126
Query: 658 RKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ V E S+ L I+ + CG++H+L ++ S +++A WG Q GL
Sbjct: 127 NQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWA--WGTGCQLGL 182
Score = 39.1 bits (87), Expect = 0.030
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-I 735
E+ + AG H++ LT K VY+ G+N +GQ G + ++ ++ + K+ EN +
Sbjct: 560 EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-----HSDFPTTV--PRLAKISSENGV 612
Query: 736 VDVCCGQDHSLFITES 783
+ G+D+SLF+ ++
Sbjct: 613 WSIAAGRDYSLFLVDT 628
>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
Length = 1598
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 2/118 (1%)
Frame = +1
Query: 484 PRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQC--G 657
P R+ P+E+ S +PI + + + VA G H+ +TD Y G N+ GQC
Sbjct: 10 PWRSGPVEICPS-SPI-LENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVA 67
Query: 658 RKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ V E S+ L I+ + CG++H+L ++ S +++A WG Q GL
Sbjct: 68 NQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWA--WGTGCQLGL 123
Score = 39.1 bits (87), Expect = 0.030
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-I 735
E+ + AG H++ LT K VY+ G+N +GQ G + ++ ++ + K+ EN +
Sbjct: 501 EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-----HSDFPTTV--PRLAKISSENGV 553
Query: 736 VDVCCGQDHSLFITES 783
+ G+D+SLF+ ++
Sbjct: 554 WSIAAGRDYSLFLVDT 569
>AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein.
Length = 396
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 2/118 (1%)
Frame = +1
Query: 484 PRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQC--G 657
P R+ P+E+ S +PI + + + VA G H+ +TD Y G N+ GQC
Sbjct: 69 PWRSGPVEICPS-SPI-LENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVA 126
Query: 658 RKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ V E S+ L I+ + CG++H+L ++ S +++A WG Q GL
Sbjct: 127 NQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWA--WGTGCQLGL 182
>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
Length = 1657
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 2/118 (1%)
Frame = +1
Query: 484 PRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQC--G 657
P R+ P+E+ S +PI + + + VA G H+ +TD Y G N+ GQC
Sbjct: 69 PWRSGPVEICPS-SPI-LENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVA 126
Query: 658 RKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ V E S+ L I+ + CG++H+L ++ S +++A WG Q GL
Sbjct: 127 NQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWA--WGTGCQLGL 182
Score = 39.1 bits (87), Expect = 0.030
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-I 735
E+ + AG H++ LT K VY+ G+N +GQ G + ++ ++ + K+ EN +
Sbjct: 560 EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-----HSDFPTTV--PRLAKISSENGV 612
Query: 736 VDVCCGQDHSLFITES 783
+ G+D+SLF+ ++
Sbjct: 613 WSIAAGRDYSLFLVDT 628
>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
Length = 1658
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 2/118 (1%)
Frame = +1
Query: 484 PRRNHPLELLLSYAPIYIPYKSLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQC--G 657
P R+ P+E+ S +PI + + + VA G H+ +TD Y G N+ GQC
Sbjct: 70 PWRSGPVEICPS-SPI-LENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVA 127
Query: 658 RKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ V E S+ L I+ + CG++H+L ++ S +++A WG Q GL
Sbjct: 128 NQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWA--WGTGCQLGL 183
Score = 39.1 bits (87), Expect = 0.030
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-I 735
E+ + AG H++ LT K VY+ G+N +GQ G + ++ ++ + K+ EN +
Sbjct: 561 EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-----HSDFPTTV--PRLAKISSENGV 613
Query: 736 VDVCCGQDHSLFITES 783
+ G+D+SLF+ ++
Sbjct: 614 WSIAAGRDYSLFLVDT 629
>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 45.6 bits (103), Expect = 3e-04
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V V CG HS+ + E+G VY G+G GQ G G+ ++R PT V
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLV 948
Score = 40.7 bits (91), Expect = 0.010
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Frame = +1
Query: 553 ECEIKAV--AAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
+CE++AV + G H+++L + VYT G +GQ G +VN ++V Q L
Sbjct: 899 DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLV----QALPG 953
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTG-----LGNYDNRSTPTAVIGDITTEK 891
+ V G +H+ + G+V+ G + GQ G + ++ + P IG K
Sbjct: 954 PS-TQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRK 1012
Query: 892 IVKVASTGD 918
+ ++GD
Sbjct: 1013 ATWIGASGD 1021
Score = 37.5 bits (83), Expect = 0.091
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-VNEEYKG 690
+ VA G+AHT +L V+T G N GQCGR +N+ KG
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKG 688
>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 45.6 bits (103), Expect = 3e-04
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V V CG HS+ + E+G VY G+G GQ G G+ ++R PT V
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLV 948
Score = 40.7 bits (91), Expect = 0.010
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Frame = +1
Query: 553 ECEIKAV--AAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
+CE++AV + G H+++L + VYT G +GQ G +VN ++V Q L
Sbjct: 899 DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLV----QALPG 953
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTG-----LGNYDNRSTPTAVIGDITTEK 891
+ V G +H+ + G+V+ G + GQ G + ++ + P IG K
Sbjct: 954 PS-TQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRK 1012
Query: 892 IVKVASTGD 918
+ ++GD
Sbjct: 1013 ATWIGASGD 1021
Score = 37.5 bits (83), Expect = 0.091
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-VNEEYKG 690
+ VA G+AHT +L V+T G N GQCGR +N+ KG
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKG 688
>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 45.6 bits (103), Expect = 3e-04
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V V CG HS+ + E+G VY G+G GQ G G+ ++R PT V
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLV 948
Score = 40.7 bits (91), Expect = 0.010
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Frame = +1
Query: 553 ECEIKAV--AAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
+CE++AV + G H+++L + VYT G +GQ G +VN ++V Q L
Sbjct: 899 DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLV----QALPG 953
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTG-----LGNYDNRSTPTAVIGDITTEK 891
+ V G +H+ + G+V+ G + GQ G + ++ + P IG K
Sbjct: 954 PS-TQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRK 1012
Query: 892 IVKVASTGD 918
+ ++GD
Sbjct: 1013 ATWIGASGD 1021
Score = 37.5 bits (83), Expect = 0.091
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-VNEEYKG 690
+ VA G+AHT +L V+T G N GQCGR +N+ KG
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKG 688
>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with Myc
protein.
Length = 4641
Score = 45.6 bits (103), Expect = 3e-04
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAV 867
V V CG HS+ + E+G VY G+G GQ G G+ ++R PT V
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLV 948
Score = 40.7 bits (91), Expect = 0.010
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Frame = +1
Query: 553 ECEIKAV--AAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
+CE++AV + G H+++L + VYT G +GQ G +VN ++V Q L
Sbjct: 899 DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLV----QALPG 953
Query: 727 ENIVDVCCGQDHSLFITESGKVYACGWGADGQTG-----LGNYDNRSTPTAVIGDITTEK 891
+ V G +H+ + G+V+ G + GQ G + ++ + P IG K
Sbjct: 954 PS-TQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRK 1012
Query: 892 IVKVASTGD 918
+ ++GD
Sbjct: 1013 ATWIGASGD 1021
Score = 37.5 bits (83), Expect = 0.091
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = +1
Query: 562 IKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVN-VNEEYKG 690
+ VA G+AHT +L V+T G N GQCGR +N+ KG
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKG 688
>AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
Length = 396
Score = 44.8 bits (101), Expect = 6e-04
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQC--GRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
VA G H+ +TD Y G N+ GQC + V E S+ L I+ +
Sbjct: 96 VATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQL 155
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGL 831
CG++H+L ++ S +++A WG Q GL
Sbjct: 156 ACGEEHTLALSISREIWA--WGTGCQLGL 182
>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
Length = 1657
Score = 44.8 bits (101), Expect = 6e-04
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQC--GRKVNVNEEYKGSMVTHNIQKLGKENIVDV 744
VA G H+ +TD Y G N+ GQC + V E S+ L I+ +
Sbjct: 96 VATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQL 155
Query: 745 CCGQDHSLFITESGKVYACGWGADGQTGL 831
CG++H+L ++ S +++A WG Q GL
Sbjct: 156 ACGEEHTLALSISREIWA--WGTGCQLGL 182
Score = 39.1 bits (87), Expect = 0.030
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKEN-I 735
E+ + AG H++ LT K VY+ G+N +GQ G + ++ ++ + K+ EN +
Sbjct: 560 EVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-----HSDFPTTV--PRLAKISSENGV 612
Query: 736 VDVCCGQDHSLFITES 783
+ G+D+SLF+ ++
Sbjct: 613 WSIAAGRDYSLFLVDT 628
>AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2
protein.
Length = 371
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/112 (31%), Positives = 52/112 (46%)
Frame = +1
Query: 571 VAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCC 750
+ G + LT V+T G Y + G + +V+ + V ++ GK+ IV V
Sbjct: 39 IECGAQFLLALTKSGVVWTWGKGDYFRLGHRSDVH--VRKPQVVEGLR--GKK-IVHVAV 93
Query: 751 GQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
G H L + +SG+VYA G GQ G G P V G + +KI+ VA
Sbjct: 94 GAQHCLAVMDSGQVYAWGDNDHGQQGNGTTTVNRKPMLVQG-LEGQKIMCVA 144
Score = 37.5 bits (83), Expect = 0.091
Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +1
Query: 619 VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYA 798
V++ G+ +G+ GR + +G + NI++L + + + CG L +T+SG V+
Sbjct: 3 VFSWGDGDFGKLGRGGS-----EGCNIPQNIERLNGQGVCQIECGAQFLLALTKSGVVWT 57
Query: 799 CGWGADGQTGLGN-YDNRSTPTAVIGDITTEKIVKVA 906
WG LG+ D V+ + +KIV VA
Sbjct: 58 --WGKGDYFRLGHRSDVHVRKPQVVEGLRGKKIVHVA 92
Score = 34.3 bits (75), Expect = 0.85
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Frame = +1
Query: 559 EIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGR-KVNVNEEYKGSMVTHNIQKLGKENI 735
+I VA G H + + D VY G+N +GQ G VN + M+ +Q L + I
Sbjct: 87 KIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQQGNGTTTVNRK---PML---VQGLEGQKI 140
Query: 736 VDVCCGQDHSL 768
+ V CG HS+
Sbjct: 141 MCVACGSSHSV 151
>AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein.
Length = 259
Score = 41.1 bits (92), Expect = 0.007
Identities = 23/53 (43%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Frame = +1
Query: 751 GQDHSLF-ITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVA 906
G + +LF +T GK+YA G+GA G+ G+G ++ STPT ++ I I KVA
Sbjct: 167 GGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPT-LLESIQHVFIKKVA 218
Score = 33.5 bits (73), Expect = 1.5
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Frame = +1
Query: 580 GRAHTIILTDKEG-VYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQ 756
G T+ +G +Y G A G+ G + E + +IQ + + + V G
Sbjct: 167 GGEQTLFAVTADGKLYATGYGAGGRLG--IGGTESVSTPTLLESIQHVFIKKVA-VNSGG 223
Query: 757 DHSLFITESGKVYACGWGADGQTGLGN 837
H L ++ G+VY+ G DG+ G GN
Sbjct: 224 KHCLALSSEGEVYSWGEAEDGKLGHGN 250
>BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein.
Length = 244
Score = 37.5 bits (83), Expect = 0.091
Identities = 18/60 (30%), Positives = 28/60 (46%)
Frame = +1
Query: 736 VDVCCGQDHSLFITESGKVYACGWGADGQTGLGNYDNRSTPTAVIGDITTEKIVKVASTG 915
V CG H+ +T +G++Y GWG GQ G + + P V + + VK + G
Sbjct: 171 VKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAVTCG 230
Score = 32.3 bits (70), Expect = 3.4
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = +1
Query: 733 IVDVCCGQDHSLFITESGKVYACGWGADGQTGL 831
+ +V G HS+ ++E+G +Y GW GQ L
Sbjct: 80 MAEVAAGGWHSVCVSETGDIYIWGWNESGQLAL 112
>AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containing
protein 4 isoform 4 protein.
Length = 110
Score = 37.5 bits (83), Expect = 0.091
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 631 GNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWG 810
GN ++GQ G ++EE + + + DV CG H++F+ + G VY CG
Sbjct: 5 GNASFGQLGLG-GIDEEIV--LEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCN 61
Query: 811 ADGQTGLGNYDNRSTP 858
GQ LG+ +R P
Sbjct: 62 DLGQ--LGHEKSRKKP 75
>AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containing
protein 4 isoform 2 protein.
Length = 117
Score = 37.5 bits (83), Expect = 0.091
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 631 GNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGKENIVDVCCGQDHSLFITESGKVYACGWG 810
GN ++GQ G ++EE + + + DV CG H++F+ + G VY CG
Sbjct: 5 GNASFGQLGLG-GIDEEIV--LEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCN 61
Query: 811 ADGQTGLGNYDNRSTP 858
GQ LG+ +R P
Sbjct: 62 DLGQ--LGHEKSRKKP 75
>BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein.
Length = 580
Score = 33.5 bits (73), Expect = 1.5
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
SL +I A G H ++ + ++ GNN YGQ G ++ +G Q
Sbjct: 354 SLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMD---RGEPT----QVCYL 406
Query: 727 ENIVDVCCGQDHSLFITESG----KVYACGWGADGQ 822
+ + + CG +HSL +++S ++ CG GA G+
Sbjct: 407 QRPITLWCGLNHSLVLSQSSEFSKELLGCGCGAGGR 442
>AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein.
Length = 580
Score = 33.5 bits (73), Expect = 1.5
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Frame = +1
Query: 547 SLECEIKAVAAGRAHTIILTDKEGVYTLGNNAYGQCGRKVNVNEEYKGSMVTHNIQKLGK 726
SL +I A G H ++ + ++ GNN YGQ G ++ +G Q
Sbjct: 354 SLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMD---RGEPT----QVCYL 406
Query: 727 ENIVDVCCGQDHSLFITESG----KVYACGWGADGQ 822
+ + + CG +HSL +++S ++ CG GA G+
Sbjct: 407 QRPITLWCGLNHSLVLSQSSEFSKELLGCGCGAGGR 442
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 156,887,208
Number of Sequences: 237096
Number of extensions: 3469686
Number of successful extensions: 11367
Number of sequences better than 10.0: 101
Number of HSP's better than 10.0 without gapping: 10336
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11098
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 16073499160
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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