Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP25_F_D24
(1144 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 223 9e-58
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 223 9e-58
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 221 5e-57
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 221 5e-57
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 132 3e-30
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 132 3e-30
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 106 2e-22
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 106 2e-22
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 106 2e-22
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 102 2e-21
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 102 2e-21
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 102 2e-21
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 102 2e-21
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 102 2e-21
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 102 2e-21
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 101 5e-21
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 101 5e-21
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 101 5e-21
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 101 5e-21
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 100 1e-20
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 100 1e-20
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 100 1e-20
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 100 1e-20
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 100 1e-20
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 100 1e-20
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 100 1e-20
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 100 1e-20
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 98 5e-20
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 98 5e-20
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 98 5e-20
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 98 5e-20
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 98 5e-20
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 98 5e-20
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 98 5e-20
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 98 6e-20
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 98 6e-20
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 98 6e-20
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 98 6e-20
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 97 1e-19
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 97 1e-19
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 97 1e-19
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 97 1e-19
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 97 1e-19
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 97 1e-19
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 97 1e-19
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 96 2e-19
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 96 2e-19
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 96 2e-19
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 96 2e-19
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 95 4e-19
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 95 4e-19
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 95 4e-19
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 95 4e-19
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 95 4e-19
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 95 6e-19
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 95 6e-19
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 95 6e-19
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 95 6e-19
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 95 6e-19
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 95 6e-19
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 95 6e-19
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 95 6e-19
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 95 6e-19
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 95 6e-19
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 95 6e-19
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 94 7e-19
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 94 7e-19
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 94 7e-19
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 94 7e-19
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 94 7e-19
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 94 7e-19
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 94 7e-19
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 93 1e-18
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 93 1e-18
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 93 1e-18
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 93 1e-18
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 93 1e-18
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 1e-18
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 1e-18
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 93 1e-18
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 93 1e-18
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 93 1e-18
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 93 1e-18
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 1e-18
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 93 1e-18
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 93 1e-18
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 93 1e-18
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 93 1e-18
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 93 1e-18
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 93 1e-18
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 93 1e-18
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 93 1e-18
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 93 1e-18
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 93 1e-18
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 93 2e-18
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 93 2e-18
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 92 4e-18
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 92 4e-18
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 92 4e-18
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 92 4e-18
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 92 4e-18
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 92 4e-18
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 92 4e-18
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 92 4e-18
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 91 5e-18
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 91 5e-18
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 91 5e-18
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 91 9e-18
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 91 9e-18
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 91 9e-18
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 90 1e-17
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 90 2e-17
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 90 2e-17
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 90 2e-17
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 90 2e-17
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 90 2e-17
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 90 2e-17
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 90 2e-17
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 89 2e-17
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 89 2e-17
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 89 2e-17
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 89 2e-17
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 89 2e-17
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 89 2e-17
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 89 2e-17
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 89 2e-17
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 89 2e-17
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 89 2e-17
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 89 2e-17
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 89 3e-17
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 89 3e-17
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 89 3e-17
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 89 3e-17
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 89 3e-17
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 89 3e-17
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 89 3e-17
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 89 3e-17
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 89 3e-17
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 89 3e-17
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 89 3e-17
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 89 3e-17
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 89 3e-17
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 89 3e-17
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 89 3e-17
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 89 3e-17
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 89 3e-17
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 89 3e-17
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 89 4e-17
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 89 4e-17
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 89 4e-17
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 88 5e-17
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 88 5e-17
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 88 6e-17
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 88 6e-17
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 88 6e-17
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 87 9e-17
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 87 9e-17
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 87 9e-17
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 87 9e-17
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 87 9e-17
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 87 9e-17
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 87 9e-17
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 87 9e-17
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 87 9e-17
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 87 9e-17
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 87 1e-16
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 87 1e-16
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 87 1e-16
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 87 1e-16
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 87 1e-16
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 87 1e-16
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 87 1e-16
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 87 1e-16
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 87 1e-16
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 87 1e-16
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 87 1e-16
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 86 2e-16
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 60 3e-16
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 85 5e-16
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 85 5e-16
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 85 5e-16
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 85 5e-16
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 85 5e-16
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 85 6e-16
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 85 6e-16
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 85 6e-16
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 85 6e-16
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 85 6e-16
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 85 6e-16
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 85 6e-16
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 85 6e-16
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 85 6e-16
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 85 6e-16
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 84 8e-16
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 84 8e-16
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 84 8e-16
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 84 8e-16
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 84 8e-16
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 84 8e-16
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 84 8e-16
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 84 8e-16
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 84 1e-15
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 84 1e-15
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 84 1e-15
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 84 1e-15
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 84 1e-15
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 84 1e-15
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 84 1e-15
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 84 1e-15
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 84 1e-15
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 84 1e-15
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 84 1e-15
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 84 1e-15
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 84 1e-15
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 84 1e-15
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 84 1e-15
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 83 1e-15
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 83 1e-15
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 83 1e-15
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 83 1e-15
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 83 1e-15
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 83 1e-15
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 83 1e-15
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 83 1e-15
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 83 1e-15
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 83 1e-15
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 83 1e-15
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 83 1e-15
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 83 1e-15
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 83 1e-15
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 83 2e-15
D63485-1|BAA09772.2| 723|Homo sapiens KIAA0151 protein. 83 2e-15
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 83 2e-15
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 83 2e-15
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 83 2e-15
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 83 2e-15
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 83 2e-15
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 83 2e-15
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 83 2e-15
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 83 2e-15
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 83 2e-15
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 83 2e-15
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 83 2e-15
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 83 2e-15
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 83 2e-15
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 83 2e-15
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 83 2e-15
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 82 3e-15
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 82 3e-15
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 82 4e-15
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 82 4e-15
DQ667176-1|ABG25921.1| 716|Homo sapiens inhibitor of kappa ligh... 82 4e-15
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 82 4e-15
BC105924-1|AAI05925.1| 716|Homo sapiens IKK-related kinase epsi... 82 4e-15
BC105923-1|AAI05924.1| 716|Homo sapiens inhibitor of kappa ligh... 82 4e-15
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 82 4e-15
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 82 4e-15
AL354681-1|CAI15250.1| 716|Homo sapiens inhibitor of kappa ligh... 82 4e-15
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 82 4e-15
AF241789-1|AAF45307.1| 716|Homo sapiens IKK epsilon protein. 82 4e-15
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 82 4e-15
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 82 4e-15
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 82 4e-15
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 82 4e-15
AB016590-1|BAA85155.1| 716|Homo sapiens inducible IkappaB kinas... 82 4e-15
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 81 6e-15
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 81 7e-15
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 81 1e-14
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 81 1e-14
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 81 1e-14
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 81 1e-14
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 81 1e-14
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 81 1e-14
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 81 1e-14
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 81 1e-14
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 81 1e-14
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 81 1e-14
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 80 1e-14
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 80 1e-14
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 80 1e-14
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 80 1e-14
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 80 1e-14
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 80 1e-14
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 80 1e-14
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 80 1e-14
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 80 1e-14
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 80 1e-14
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 80 1e-14
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 80 1e-14
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 80 1e-14
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 80 1e-14
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 80 1e-14
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 80 1e-14
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 80 1e-14
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 80 1e-14
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 80 1e-14
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 80 1e-14
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 80 1e-14
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 80 2e-14
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 80 2e-14
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 80 2e-14
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 80 2e-14
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 80 2e-14
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 80 2e-14
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 80 2e-14
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 80 2e-14
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 80 2e-14
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 80 2e-14
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 80 2e-14
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 80 2e-14
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 80 2e-14
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 80 2e-14
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 80 2e-14
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 80 2e-14
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 80 2e-14
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 80 2e-14
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 80 2e-14
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 80 2e-14
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 80 2e-14
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 80 2e-14
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 80 2e-14
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 80 2e-14
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 80 2e-14
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 80 2e-14
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 80 2e-14
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 80 2e-14
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 79 2e-14
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 79 2e-14
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 79 2e-14
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 79 2e-14
BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein. 79 2e-14
BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein. 79 2e-14
AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa ligh... 79 2e-14
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 79 2e-14
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 79 2e-14
AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein. 79 2e-14
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 79 2e-14
AF031416-1|AAC64675.1| 756|Homo sapiens IkB kinase beta subunit... 79 2e-14
AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein. 79 2e-14
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 79 2e-14
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 79 3e-14
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 79 3e-14
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 79 3e-14
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 79 3e-14
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 79 3e-14
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 79 3e-14
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 79 3e-14
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 79 3e-14
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 79 3e-14
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 79 3e-14
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 79 3e-14
AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 79 3e-14
AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 79 3e-14
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 79 3e-14
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 79 3e-14
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 79 3e-14
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 79 3e-14
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 79 3e-14
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 79 3e-14
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 79 3e-14
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 79 3e-14
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 79 3e-14
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 79 3e-14
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 79 3e-14
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 79 3e-14
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 79 4e-14
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 79 4e-14
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 79 4e-14
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 79 4e-14
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 79 4e-14
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 79 4e-14
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 79 4e-14
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 79 4e-14
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 79 4e-14
AL357131-3|CAH72011.1| 280|Homo sapiens PCTAIRE protein kinase ... 79 4e-14
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 79 4e-14
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 79 4e-14
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 79 4e-14
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 79 4e-14
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 79 4e-14
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 79 4e-14
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 79 4e-14
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 79 4e-14
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 78 5e-14
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 78 5e-14
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 78 5e-14
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 78 5e-14
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 5e-14
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 78 5e-14
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 5e-14
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 5e-14
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 5e-14
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 78 5e-14
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 78 5e-14
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 78 5e-14
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 78 7e-14
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 78 7e-14
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 78 7e-14
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 78 7e-14
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 78 7e-14
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 78 7e-14
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 78 7e-14
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 78 7e-14
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 78 7e-14
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 78 7e-14
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 78 7e-14
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 78 7e-14
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 78 7e-14
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 77 9e-14
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 77 9e-14
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 77 9e-14
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 77 9e-14
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 77 9e-14
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 77 9e-14
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 77 9e-14
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 77 9e-14
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 77 9e-14
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 77 9e-14
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 77 9e-14
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 77 9e-14
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 77 9e-14
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 77 9e-14
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 77 9e-14
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 77 9e-14
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 77 9e-14
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 77 9e-14
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 77 9e-14
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 77 9e-14
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 77 9e-14
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 77 9e-14
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 77 9e-14
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 77 9e-14
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 77 9e-14
BC028713-1|AAH28713.1| 341|Homo sapiens PDLIM1 interacting kina... 67 9e-14
AL391650-6|CAI17135.1| 341|Homo sapiens PDLIM1 interacting kina... 67 9e-14
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 77 1e-13
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 77 1e-13
BC028079-1|AAH28079.1| 556|Homo sapiens RPS6KA4 protein protein. 77 1e-13
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 77 1e-13
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 77 2e-13
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 77 2e-13
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 77 2e-13
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 77 2e-13
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 77 2e-13
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 77 2e-13
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 77 2e-13
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 77 2e-13
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 76 2e-13
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 76 2e-13
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 76 2e-13
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 76 2e-13
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 76 2e-13
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 76 2e-13
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 76 2e-13
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 76 2e-13
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 76 2e-13
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 76 2e-13
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 76 2e-13
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 76 2e-13
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 76 2e-13
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 76 2e-13
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 76 2e-13
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 76 2e-13
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 76 2e-13
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 76 2e-13
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 76 2e-13
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 76 2e-13
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 223 bits (545), Expect = 9e-58
Identities = 112/208 (53%), Positives = 146/208 (70%)
Frame = +2
Query: 290 MEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIK 469
MEV VGD+E++K+D++GHGAFA+V++GR R+ VA+K + KK + K+ +L KEIK
Sbjct: 1 MEV--VGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIK 58
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+EL QH+N+VA++D + P V++VMEYCNGGDLADYLQ LSE TI++FL Q+
Sbjct: 59 ILKEL---QHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQI 115
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
A AM +H+KGI+HRDLKP NILL+++ R S I KI DFGF R+L M T
Sbjct: 116 AAAMRILHSKGIIHRDLKPQNILLSYA--NRRKSSVSGIRIKIADFGFARYLHSNMMAAT 173
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
L GSPMYM P IMS AK LWS+G
Sbjct: 174 LCGSPMYMAPEVIMSQHYDAKADLWSIG 201
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 223 bits (545), Expect = 9e-58
Identities = 112/208 (53%), Positives = 146/208 (70%)
Frame = +2
Query: 290 MEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIK 469
MEV VGD+E++K+D++GHGAFA+V++GR R+ VA+K + KK + K+ +L KEIK
Sbjct: 65 MEV--VGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIK 122
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+EL QH+N+VA++D + P V++VMEYCNGGDLADYLQ LSE TI++FL Q+
Sbjct: 123 ILKEL---QHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQI 179
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
A AM +H+KGI+HRDLKP NILL+++ R S I KI DFGF R+L M T
Sbjct: 180 AAAMRILHSKGIIHRDLKPQNILLSYA--NRRKSSVSGIRIKIADFGFARYLHSNMMAAT 237
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
L GSPMYM P IMS AK LWS+G
Sbjct: 238 LCGSPMYMAPEVIMSQHYDAKADLWSIG 265
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 221 bits (539), Expect = 5e-57
Identities = 110/203 (54%), Positives = 140/203 (68%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG +EF+++D+IGHGAFA+V+KGR R+ VAVK + KK + K+ +L KEIKIL+EL
Sbjct: 11 VGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKEL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
+H+N+VA++D + VY+VMEYCNGGDLADYL R LSE TI+LFL Q+A AM
Sbjct: 71 ---KHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMR 127
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
+H+KGI+HRDLKP NILL++ R P+ I KI DFGF R+L M TL GSP
Sbjct: 128 LLHSKGIIHRDLKPQNILLSNP--AGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSP 185
Query: 845 MYMXPXXIMSLKIXAKXXLWSLG 913
MYM P IMS K LWS+G
Sbjct: 186 MYMAPEVIMSQHYDGKADLWSIG 208
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 221 bits (539), Expect = 5e-57
Identities = 110/203 (54%), Positives = 140/203 (68%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG +EF+++D+IGHGAFA+V+KGR R+ VAVK + KK + K+ +L KEIKIL+EL
Sbjct: 27 VGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKEL 86
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
+H+N+VA++D + VY+VMEYCNGGDLADYL R LSE TI+LFL Q+A AM
Sbjct: 87 ---KHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMR 143
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
+H+KGI+HRDLKP NILL++ R P+ I KI DFGF R+L M TL GSP
Sbjct: 144 LLHSKGIIHRDLKPQNILLSNP--AGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSP 201
Query: 845 MYMXPXXIMSLKIXAKXXLWSLG 913
MYM P IMS K LWS+G
Sbjct: 202 MYMAPEVIMSQHYDGKADLWSIG 224
>BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 132 bits (318), Expect = 3e-30
Identities = 72/199 (36%), Positives = 112/199 (56%), Gaps = 1/199 (0%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRELTALQ 496
F + +G G +A VYK +K+ + VA+K V KK + KAS E L+ EI+IL+ ++
Sbjct: 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILK---GIR 70
Query: 497 HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHA 676
H ++V + D +Y++ME+C GGDL+ ++ T R+L E ++F+ QLA A+ +H
Sbjct: 71 HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHE 130
Query: 677 KGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMX 856
+ I H DLKP NILL+ P K+ DFGF + + + L GSP+YM
Sbjct: 131 RNISHLDLKPQNILLSSLEKPH---------LKLADFGFAQHMSPWDEKHVLRGSPLYMA 181
Query: 857 PXXIMSLKIXAKXXLWSLG 913
P + + A+ LWS+G
Sbjct: 182 PEMVCQRQYDARVDLWSMG 200
>BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 132 bits (318), Expect = 3e-30
Identities = 72/199 (36%), Positives = 112/199 (56%), Gaps = 1/199 (0%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRELTALQ 496
F + +G G +A VYK +K+ + VA+K V KK + KAS E L+ EI+IL+ ++
Sbjct: 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILK---GIR 70
Query: 497 HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHA 676
H ++V + D +Y++ME+C GGDL+ ++ T R+L E ++F+ QLA A+ +H
Sbjct: 71 HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHE 130
Query: 677 KGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMX 856
+ I H DLKP NILL+ P K+ DFGF + + + L GSP+YM
Sbjct: 131 RNISHLDLKPQNILLSSLEKPH---------LKLADFGFAQHMSPWDEKHVLRGSPLYMA 181
Query: 857 PXXIMSLKIXAKXXLWSLG 913
P + + A+ LWS+G
Sbjct: 182 PEMVCQRQYDARVDLWSMG 200
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 106 bits (254), Expect = 2e-22
Identities = 72/196 (36%), Positives = 104/196 (53%), Gaps = 2/196 (1%)
Frame = +2
Query: 332 DIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG-IQKASEILVKEIKILRELTALQHKNL 508
++IG G+F VYKGR RK +Q VA+K + K G +K L +EI+I+R L+H N+
Sbjct: 8 EMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQREIEIMR---GLRHPNI 63
Query: 509 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
V M D ++ V VV +Y G +L L+ + L E +Q AQL A+ +H+ I+
Sbjct: 64 VHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRIL 122
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT-LXGSPMYMXPXX 865
HRD+KP NILL I K+ DFGF R + M +T + G+P+YM P
Sbjct: 123 HRDMKPQNILLAKG---------GGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 171
Query: 866 IMSLKIXAKXXLWSLG 913
+ LWS+G
Sbjct: 172 VEERPYDHTADLWSVG 187
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 106 bits (254), Expect = 2e-22
Identities = 72/196 (36%), Positives = 104/196 (53%), Gaps = 2/196 (1%)
Frame = +2
Query: 332 DIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG-IQKASEILVKEIKILRELTALQHKNL 508
++IG G+F VYKGR RK +Q VA+K + K G +K L +EI+I+R L+H N+
Sbjct: 8 EMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQREIEIMR---GLRHPNI 63
Query: 509 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
V M D ++ V VV +Y G +L L+ + L E +Q AQL A+ +H+ I+
Sbjct: 64 VHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRIL 122
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT-LXGSPMYMXPXX 865
HRD+KP NILL I K+ DFGF R + M +T + G+P+YM P
Sbjct: 123 HRDMKPQNILLAKG---------GGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 171
Query: 866 IMSLKIXAKXXLWSLG 913
+ LWS+G
Sbjct: 172 VEERPYDHTADLWSVG 187
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 106 bits (254), Expect = 2e-22
Identities = 72/196 (36%), Positives = 104/196 (53%), Gaps = 2/196 (1%)
Frame = +2
Query: 332 DIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG-IQKASEILVKEIKILRELTALQHKNL 508
++IG G+F VYKGR RK +Q VA+K + K G +K L +EI+I+R L+H N+
Sbjct: 25 EMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQREIEIMR---GLRHPNI 80
Query: 509 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
V M D ++ V VV +Y G +L L+ + L E +Q AQL A+ +H+ I+
Sbjct: 81 VHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRIL 139
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT-LXGSPMYMXPXX 865
HRD+KP NILL I K+ DFGF R + M +T + G+P+YM P
Sbjct: 140 HRDMKPQNILLAKG---------GGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 188
Query: 866 IMSLKIXAKXXLWSLG 913
+ LWS+G
Sbjct: 189 VEERPYDHTADLWSVG 204
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 102 bits (245), Expect = 2e-21
Identities = 68/205 (33%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 17 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 72
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 73 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 130
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF GN T GS
Sbjct: 131 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 179
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 180 PPYAAPELFQGKKYDGPEVDVWSLG 204
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 102 bits (245), Expect = 2e-21
Identities = 68/205 (33%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 17 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 72
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 73 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 130
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF GN T GS
Sbjct: 131 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 179
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 180 PPYAAPELFQGKKYDGPEVDVWSLG 204
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 102 bits (245), Expect = 2e-21
Identities = 68/205 (33%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 50 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 105
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 106 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 163
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF GN T GS
Sbjct: 164 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 212
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 213 PPYAAPELFQGKKYDGPEVDVWSLG 237
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 102 bits (245), Expect = 2e-21
Identities = 68/205 (33%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 40 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 95
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 96 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 153
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF GN T GS
Sbjct: 154 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 202
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 203 PPYAAPELFQGKKYDGPEVDVWSLG 227
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 102 bits (245), Expect = 2e-21
Identities = 68/205 (33%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 17 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 72
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 73 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 130
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF GN T GS
Sbjct: 131 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 179
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 180 PPYAAPELFQGKKYDGPEVDVWSLG 204
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 102 bits (245), Expect = 2e-21
Identities = 68/205 (33%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 50 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 105
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 106 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 163
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF GN T GS
Sbjct: 164 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 212
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 213 PPYAAPELFQGKKYDGPEVDVWSLG 237
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 101 bits (242), Expect = 5e-21
Identities = 68/205 (33%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL D+ KI DFGF GN T GS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 220 PPYAAPELFQGKKYDGPEVDVWSLG 244
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 101 bits (242), Expect = 5e-21
Identities = 68/205 (33%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL D+ KI DFGF GN T GS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 220 PPYAAPELFQGKKYDGPEVDVWSLG 244
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 101 bits (242), Expect = 5e-21
Identities = 68/205 (33%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL D+ KI DFGF GN T GS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 220 PPYAAPELFQGKKYDGPEVDVWSLG 244
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 101 bits (242), Expect = 5e-21
Identities = 68/205 (33%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL D+ KI DFGF GN T GS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 220 PPYAAPELFQGKKYDGPEVDVWSLG 244
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 100 bits (239), Expect = 1e-20
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 5/197 (2%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 502
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 503 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 682
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 683 IVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPX 862
I H DLKP NI+L L P P K+ DFG + GN + G+P ++ P
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 863 XIMSLKIXAKXXLWSLG 913
+ + + +WS+G
Sbjct: 188 IVNYEPLGLEADMWSIG 204
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 100 bits (239), Expect = 1e-20
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 5/197 (2%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 502
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 503 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 682
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 683 IVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPX 862
I H DLKP NI+L L P P K+ DFG + GN + G+P ++ P
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 863 XIMSLKIXAKXXLWSLG 913
+ + + +WS+G
Sbjct: 188 IVNYEPLGLEADMWSIG 204
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 100 bits (239), Expect = 1e-20
Identities = 61/207 (29%), Positives = 108/207 (52%), Gaps = 2/207 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 15 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 71
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 72 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 128
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ H + IVHRDLK N+LL +++ KI DFGF F G + T
Sbjct: 129 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 177
Query: 836 GSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WS+G
Sbjct: 178 GSPPYAAPEVFEGQQYEGPQLDIWSMG 204
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 100 bits (239), Expect = 1e-20
Identities = 61/207 (29%), Positives = 108/207 (52%), Gaps = 2/207 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 15 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 71
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 72 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 128
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ H + IVHRDLK N+LL +++ KI DFGF F G + T
Sbjct: 129 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 177
Query: 836 GSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WS+G
Sbjct: 178 GSPPYAAPEVFEGQQYEGPQLDIWSMG 204
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 100 bits (239), Expect = 1e-20
Identities = 61/207 (29%), Positives = 108/207 (52%), Gaps = 2/207 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 13 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 69
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 70 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 126
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ H + IVHRDLK N+LL +++ KI DFGF F G + T
Sbjct: 127 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 175
Query: 836 GSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WS+G
Sbjct: 176 GSPPYAAPEVFEGQQYEGPQLDIWSMG 202
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 100 bits (239), Expect = 1e-20
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 5/197 (2%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 502
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 503 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 682
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 683 IVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPX 862
I H DLKP NI+L L P P K+ DFG + GN + G+P ++ P
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 863 XIMSLKIXAKXXLWSLG 913
+ + + +WS+G
Sbjct: 188 IVNYEPLGLEADMWSIG 204
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 100 bits (239), Expect = 1e-20
Identities = 61/207 (29%), Positives = 108/207 (52%), Gaps = 2/207 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 39 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 95
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 96 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 152
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ H + IVHRDLK N+LL +++ KI DFGF F G + T
Sbjct: 153 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 201
Query: 836 GSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WS+G
Sbjct: 202 GSPPYAAPEVFEGQQYEGPQLDIWSMG 228
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 100 bits (239), Expect = 1e-20
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 5/197 (2%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 502
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 503 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 682
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 683 IVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPX 862
I H DLKP NI+L L P P K+ DFG + GN + G+P ++ P
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 863 XIMSLKIXAKXXLWSLG 913
+ + + +WS+G
Sbjct: 188 IVNYEPLGLEADMWSIG 204
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 98.3 bits (234), Expect = 5e-20
Identities = 65/205 (31%), Positives = 100/205 (48%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y++MEY +GG++ DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF G T GS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLG 240
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 98.3 bits (234), Expect = 5e-20
Identities = 65/205 (31%), Positives = 100/205 (48%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y++MEY +GG++ DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF G T GS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLG 240
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 98.3 bits (234), Expect = 5e-20
Identities = 65/205 (31%), Positives = 100/205 (48%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y++MEY +GG++ DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF G T GS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLG 240
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 98.3 bits (234), Expect = 5e-20
Identities = 60/198 (30%), Positives = 100/198 (50%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N LL +S + I DFG + G++ T G+P Y+ P
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 191 EVLAQKPYSKAVDCWSIG 208
>BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein.
Length = 363
Score = 97.9 bits (233), Expect = 6e-20
Identities = 62/202 (30%), Positives = 103/202 (50%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 34 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 89
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 667
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 90 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 149
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 150 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 201
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P +++ +WS+G
Sbjct: 202 YLAPEVLLNQGYNRSLDMWSVG 223
>AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90785 fis, clone THYRO1001457, moderately
similar to H.sapiens mRNA for protein kinase C mu. ).
Length = 721
Score = 97.9 bits (233), Expect = 6e-20
Identities = 62/202 (30%), Positives = 103/202 (50%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 392 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 447
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 667
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 448 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 507
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 508 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 559
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P +++ +WS+G
Sbjct: 560 YLAPEVLLNQGYNRSLDMWSVG 581
>AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90192 fis, clone MAMMA1001150, moderately
similar to PROTEIN KINASE C, MU TYPE (EC 2.7.1.-). ).
Length = 721
Score = 97.9 bits (233), Expect = 6e-20
Identities = 62/202 (30%), Positives = 103/202 (50%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 392 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 447
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 667
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 448 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 507
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 508 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 559
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P +++ +WS+G
Sbjct: 560 YLAPEVLLNQGYNRSLDMWSVG 581
>AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein.
Length = 878
Score = 97.9 bits (233), Expect = 6e-20
Identities = 62/202 (30%), Positives = 103/202 (50%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 549 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 604
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 667
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 605 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 664
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 665 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 716
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P +++ +WS+G
Sbjct: 717 YLAPEVLLNQGYNRSLDMWSVG 738
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 97.1 bits (231), Expect = 1e-19
Identities = 65/205 (31%), Positives = 99/205 (48%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y++MEY +GG + DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF G T GS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLG 240
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 97.1 bits (231), Expect = 1e-19
Identities = 58/200 (29%), Positives = 102/200 (51%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
Y+F +D++G GAF+ V ++ + VA+K + K+ ++ + EI +L ++
Sbjct: 20 YDF--RDVLGTGAFSEVILAEDKRT-QKLVAIKCIAKEALEGKEGSMENEIAVLHKI--- 73
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
+H N+VA+ D +S ++Y++M+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
GIVHRDLKP N LL +S+ D I DFG + G++ T G+P Y+
Sbjct: 134 DLGIVHRDLKPEN-LLYYSL-------DEDSKIMISDFGLSKMEDPGSVLSTACGTPGYV 185
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P + WS+G
Sbjct: 186 APEVLAQKPYSKAVDCWSIG 205
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 97.1 bits (231), Expect = 1e-19
Identities = 58/200 (29%), Positives = 102/200 (51%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
Y+F +D++G GAF+ V ++ + VA+K + K+ ++ + EI +L ++
Sbjct: 20 YDF--RDVLGTGAFSEVILAEDKRT-QKLVAIKCIAKEALEGKEGSMENEIAVLHKI--- 73
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
+H N+VA+ D +S ++Y++M+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
GIVHRDLKP N LL +S+ D I DFG + G++ T G+P Y+
Sbjct: 134 DLGIVHRDLKPEN-LLYYSL-------DEDSKIMISDFGLSKMEDPGSVLSTACGTPGYV 185
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P + WS+G
Sbjct: 186 APEVLAQKPYSKAVDCWSIG 205
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 97.1 bits (231), Expect = 1e-19
Identities = 58/200 (29%), Positives = 102/200 (51%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
Y+F +D++G GAF+ V ++ + VA+K + K+ ++ + EI +L ++
Sbjct: 20 YDF--RDVLGTGAFSEVILAEDKRT-QKLVAIKCIAKEALEGKEGSMENEIAVLHKI--- 73
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
+H N+VA+ D +S ++Y++M+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
GIVHRDLKP N LL +S+ D I DFG + G++ T G+P Y+
Sbjct: 134 DLGIVHRDLKPEN-LLYYSL-------DEDSKIMISDFGLSKMEDPGSVLSTACGTPGYV 185
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P + WS+G
Sbjct: 186 APEVLAQKPYSKAVDCWSIG 205
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 97.1 bits (231), Expect = 1e-19
Identities = 65/205 (31%), Positives = 99/205 (48%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y++MEY +GG + DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL +D+ KI DFGF G T GS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLG 240
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 97.1 bits (231), Expect = 1e-19
Identities = 56/193 (29%), Positives = 100/193 (51%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
+IG G FA+V + R R+ Q+ A+K++ K ++ +++ EI I++ L+ H N+V
Sbjct: 321 VIGDGNFAVVKECRHRET-RQAYAMKIIDKSRLKGKEDMVDSEILIIQSLS---HPNIVK 376
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 694
+H+ ++ +Y+++EY GGDL D + + E L + L +A+ +H K IVHR
Sbjct: 377 LHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHR 436
Query: 695 DLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMS 874
DLKP N+L+ + T K+ DFG + + T+ G+P Y+ P +
Sbjct: 437 DLKPENLLVQRN-------EDKSTTLKLADFGLAKHVV--RPIFTVCGTPTYVAPEILSE 487
Query: 875 LKIXAKXXLWSLG 913
+ +W+ G
Sbjct: 488 KGYGLEVDMWAAG 500
>AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein.
Length = 890
Score = 96.7 bits (230), Expect = 1e-19
Identities = 62/202 (30%), Positives = 100/202 (49%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VA+KV+ K E ++ E+ IL+ L
Sbjct: 574 YQIFADEVLGSGQFGIVYGGKHRKT-GRDVAIKVIDKMRFPTKQESQLRNEVAILQNL-- 630
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAMSA 667
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 631 -HHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRN 689
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 690 LHFKNIVHCDLKPENVLLASA-----EPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 741
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P + S +WS+G
Sbjct: 742 YLAPEVLRSKGYNRSLDMWSVG 763
>AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase
protein.
Length = 890
Score = 96.7 bits (230), Expect = 1e-19
Identities = 62/202 (30%), Positives = 100/202 (49%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VA+KV+ K E ++ E+ IL+ L
Sbjct: 574 YQIFADEVLGSGQFGIVYGGKHRKT-GRDVAIKVIDKMRFPTKQESQLRNEVAILQNL-- 630
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAMSA 667
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 631 -HHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRN 689
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 690 LHFKNIVHCDLKPENVLLASA-----EPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 741
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P + S +WS+G
Sbjct: 742 YLAPEVLRSKGYNRSLDMWSVG 763
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 95.9 bits (228), Expect = 2e-19
Identities = 64/205 (31%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL ++ KI DFGF G+ T GS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 219 PPYAAPELFQGKKYDGPEVDIWSLG 243
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 95.9 bits (228), Expect = 2e-19
Identities = 64/205 (31%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL ++ KI DFGF G+ T GS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 219 PPYAAPELFQGKKYDGPEVDIWSLG 243
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 95.9 bits (228), Expect = 2e-19
Identities = 64/205 (31%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL ++ KI DFGF G+ T GS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 219 PPYAAPELFQGKKYDGPEVDIWSLG 243
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 95.9 bits (228), Expect = 2e-19
Identities = 64/205 (31%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 57 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 112
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 113 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 170
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL ++ KI DFGF G+ T GS
Sbjct: 171 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 219
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 220 PPYAAPELFQGKKYDGPEVDIWSLG 244
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 95.1 bits (226), Expect = 4e-19
Identities = 62/198 (31%), Positives = 102/198 (51%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP P D KI DFG + + + T+ G+P Y P
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 211 EILRGCAYGPEVDMWSVG 228
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 95.1 bits (226), Expect = 4e-19
Identities = 62/198 (31%), Positives = 102/198 (51%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP P D KI DFG + + + T+ G+P Y P
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 211 EILRGCAYGPEVDMWSVG 228
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 95.1 bits (226), Expect = 4e-19
Identities = 62/198 (31%), Positives = 102/198 (51%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP P D KI DFG + + + T+ G+P Y P
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 211 EILRGCAYGPEVDMWSVG 228
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 95.1 bits (226), Expect = 4e-19
Identities = 62/198 (31%), Positives = 102/198 (51%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP P D KI DFG + + + T+ G+P Y P
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 211 EILRGCAYGPEVDMWSVG 228
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 95.1 bits (226), Expect = 4e-19
Identities = 62/198 (31%), Positives = 102/198 (51%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 76 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 128
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 129 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 188
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP P D KI DFG + + + T+ G+P Y P
Sbjct: 189 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 240
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 241 EILRGCAYGPEVDMWSVG 258
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 177 IFGTPEFVAPEIVNYEPLGLEADMWSIG 204
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 177 IFGTPEFVAPEIVNYEPLGLEADMWSIG 204
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 177 IFGTPEFVAPEIVNYEPLGLEADMWSIG 204
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 177 IFGTPEFVAPEIVNYEPLGLEADMWSIG 204
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 94.7 bits (225), Expect = 6e-19
Identities = 54/200 (27%), Positives = 102/200 (51%), Gaps = 2/200 (1%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
+T I+G G+F +V + ++ ++ KV +K A ++L +E+ IL+ +++H
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK---SVKH 172
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
++++ + ++P +Y+VME C G+L + L SE + + LA A++ +H
Sbjct: 173 EHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNN 232
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGF--XRFLXXGNMXVTLXGSPMYM 853
IVHRDLK NI++ S++ ++ K+ DFG + M G+P+YM
Sbjct: 233 DIVHRDLKLENIMVKSSLIDDNNEI--NLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYM 290
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I + + +WS+G
Sbjct: 291 APEVISAHDYSQQCDIWSIG 310
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 177 IFGTPEFVAPEIVNYEPLGLEADMWSIG 204
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 177 IFGTPEFVAPEIVNYEPLGLEADMWSIG 204
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 177 IFGTPEFVAPEIVNYEPLGLEADMWSIG 204
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 94.7 bits (225), Expect = 6e-19
Identities = 54/200 (27%), Positives = 102/200 (51%), Gaps = 2/200 (1%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
+T I+G G+F +V + ++ ++ KV +K A ++L +E+ IL+ +++H
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK---SVKH 172
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
++++ + ++P +Y+VME C G+L + L SE + + LA A++ +H
Sbjct: 173 EHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNN 232
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGF--XRFLXXGNMXVTLXGSPMYM 853
IVHRDLK NI++ S++ ++ K+ DFG + M G+P+YM
Sbjct: 233 DIVHRDLKLENIMVKSSLIDDNNEI--NLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYM 290
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I + + +WS+G
Sbjct: 291 APEVISAHDYSQQCDIWSIG 310
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 94.7 bits (225), Expect = 6e-19
Identities = 54/200 (27%), Positives = 102/200 (51%), Gaps = 2/200 (1%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
+T I+G G+F +V + ++ ++ KV +K A ++L +E+ IL+ +++H
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK---SVKH 172
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
++++ + ++P +Y+VME C G+L + L SE + + LA A++ +H
Sbjct: 173 EHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNN 232
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGF--XRFLXXGNMXVTLXGSPMYM 853
IVHRDLK NI++ S++ ++ K+ DFG + M G+P+YM
Sbjct: 233 DIVHRDLKLENIMVKSSLIDDNNEI--NLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYM 290
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I + + +WS+G
Sbjct: 291 APEVISAHDYSQQCDIWSIG 310
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 5/208 (2%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 469
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 12 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 69
Query: 470 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 649
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 70 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 126
Query: 650 AEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVT 829
+ +H+ I H DLKP NI+L L P P KI DFG + GN
Sbjct: 127 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 179
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P ++ P + + + +WS+G
Sbjct: 180 IFGTPEFVAPEIVNYEPLGLEADMWSIG 207
>X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein.
Length = 912
Score = 94.3 bits (224), Expect = 7e-19
Identities = 60/202 (29%), Positives = 100/202 (49%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VA+K++ K E ++ E+ IL+ L
Sbjct: 581 YQIFPDEVLGSGQFGIVYGGKHRKT-GRDVAIKIIDKLRFPTKQESQLRNEVAILQNL-- 637
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 667
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 638 -HHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRH 696
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 697 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 748
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P + + +WS+G
Sbjct: 749 YLAPEVLRNKGYNRSLDMWSVG 770
>DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein.
Length = 914
Score = 94.3 bits (224), Expect = 7e-19
Identities = 60/202 (29%), Positives = 100/202 (49%), Gaps = 2/202 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 490
Y+ +++G G F +VY G+ RK + VA+K++ K E ++ E+ IL+ L
Sbjct: 583 YQIFPDEVLGSGQFGIVYGGKHRKT-GRDVAIKIIDKLRFPTKQESQLRNEVAILQNL-- 639
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 667
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 640 -HHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRH 698
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
+H K IVH DLKP N+LL + P P K+ DFGF R + + ++ G+P
Sbjct: 699 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 750
Query: 848 YMXPXXIMSLKIXAKXXLWSLG 913
Y+ P + + +WS+G
Sbjct: 751 YLAPEVLRNKGYNRSLDMWSVG 772
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 94.3 bits (224), Expect = 7e-19
Identities = 63/207 (30%), Positives = 106/207 (51%), Gaps = 2/207 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 22 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 78
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 79 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 135
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ H IVHRDLK N+LL ++ DI K+ DFGF F G T
Sbjct: 136 AVEYCHDHHIVHRDLKTENLLLDGNM---------DI--KLADFGFGNFYKSGEPLSTWC 184
Query: 836 GSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WSLG
Sbjct: 185 GSPPYAAPEVFEGKEYEGPQLDIWSLG 211
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 94.3 bits (224), Expect = 7e-19
Identities = 62/203 (30%), Positives = 101/203 (49%), Gaps = 3/203 (1%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILV--KEIKILRELT 487
YEF + +G G + V K R+ + + VA+K + K I+ +++ +EI+I+ +
Sbjct: 53 YEFL--ETLGKGTYGKVKKARE--SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIM---S 105
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
+L H +++A+H+ ++ + + +VMEY + GDL DY+ + LSE + F Q+ A+
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
H +VHRDLK NILL ++ KI DFG G T GSP+
Sbjct: 166 CHQNRVVHRDLKLENILL-----------DANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214
Query: 848 YMXPXXIMSLKIXA-KXXLWSLG 913
Y P + + WSLG
Sbjct: 215 YASPEIVNGKPYTGPEVDSWSLG 237
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 94.3 bits (224), Expect = 7e-19
Identities = 63/207 (30%), Positives = 106/207 (51%), Gaps = 2/207 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 3 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 59
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 60 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 116
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ H IVHRDLK N+LL ++ DI K+ DFGF F G T
Sbjct: 117 AVEYCHDHHIVHRDLKTENLLLDGNM---------DI--KLADFGFGNFYKSGEPLSTWC 165
Query: 836 GSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WSLG
Sbjct: 166 GSPPYAAPEVFEGKEYEGPQLDIWSLG 192
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 94.3 bits (224), Expect = 7e-19
Identities = 62/203 (30%), Positives = 101/203 (49%), Gaps = 3/203 (1%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILV--KEIKILRELT 487
YEF + +G G + V K R+ + + VA+K + K I+ +++ +EI+I+ +
Sbjct: 53 YEFL--ETLGKGTYGKVKKARE--SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIM---S 105
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
+L H +++A+H+ ++ + + +VMEY + GDL DY+ + LSE + F Q+ A+
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
H +VHRDLK NILL ++ KI DFG G T GSP+
Sbjct: 166 CHQNRVVHRDLKLENILL-----------DANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214
Query: 848 YMXPXXIMSLKIXA-KXXLWSLG 913
Y P + + WSLG
Sbjct: 215 YASPEIVNGKPYTGPEVDSWSLG 237
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 94.3 bits (224), Expect = 7e-19
Identities = 63/207 (30%), Positives = 106/207 (51%), Gaps = 2/207 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 22 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 78
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 79 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 135
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ H IVHRDLK N+LL ++ DI K+ DFGF F G T
Sbjct: 136 AVEYCHDHHIVHRDLKTENLLLDGNM---------DI--KLADFGFGNFYKSGEPLSTWC 184
Query: 836 GSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WSLG
Sbjct: 185 GSPPYAAPEVFEGKEYEGPQLDIWSLG 211
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 262 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 320
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 321 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 376
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 377 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 428
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 429 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 457
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 93.5 bits (222), Expect = 1e-18
Identities = 60/195 (30%), Positives = 99/195 (50%), Gaps = 3/195 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ---HKNL 508
+G G FA+V K R+ K+ A K + KK +AS V +I RE++ L+ H N+
Sbjct: 29 LGSGQFAIVKKCRE-KSTGLEYAAKFI-KKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
Query: 509 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
+ +HD ++ V +++E +GG+L D+L LSE F+ Q+ + ++ +H K I
Sbjct: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIA 146
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXI 868
H DLKP NI+L L P P K+ DFG + G + G+P ++ P +
Sbjct: 147 HFDLKPENIML----LDKNIPIPH---IKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV 199
Query: 869 MSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 200 NYEPLGLEADMWSIG 214
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 93.5 bits (222), Expect = 1e-18
Identities = 62/196 (31%), Positives = 98/196 (50%), Gaps = 3/196 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXX 865
HRD+K NI LT + L K+ D+G + L +M TL G+P YM P
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
Query: 866 IMSLKIXAKXXLWSLG 913
+K K +W++G
Sbjct: 223 CQGVKYNFKSDIWAVG 238
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 93.5 bits (222), Expect = 1e-18
Identities = 62/196 (31%), Positives = 98/196 (50%), Gaps = 3/196 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXX 865
HRD+K NI LT + L K+ D+G + L +M TL G+P YM P
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
Query: 866 IMSLKIXAKXXLWSLG 913
+K K +W++G
Sbjct: 223 CQGVKYNFKSDIWAVG 238
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 93.5 bits (222), Expect = 1e-18
Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G K + VAVK++ ++ I ++ +++ K + ++
Sbjct: 13 VKIGHYILG--DTLGVGTFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQ 68
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P+ +++VMEY +GG+L DY+ N L E + Q+
Sbjct: 69 NLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSG 128
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 129 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 177
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 178 SPNYAAPEVISGRLYAGPEVDIWSSG 203
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 128 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 186
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 187 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 242
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 243 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 294
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 295 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 323
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 262 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 320
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 321 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 376
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 377 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 428
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 429 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 457
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 93.5 bits (222), Expect = 1e-18
Identities = 62/196 (31%), Positives = 98/196 (50%), Gaps = 3/196 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXX 865
HRD+K NI LT + L K+ D+G + L +M TL G+P YM P
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
Query: 866 IMSLKIXAKXXLWSLG 913
+K K +W++G
Sbjct: 223 CQGVKYNFKSDIWAVG 238
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 93.5 bits (222), Expect = 1e-18
Identities = 62/196 (31%), Positives = 98/196 (50%), Gaps = 3/196 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXX 865
HRD+K NI LT + L K+ D+G + L +M TL G+P YM P
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
Query: 866 IMSLKIXAKXXLWSLG 913
+K K +W++G
Sbjct: 223 CQGVKYNFKSDIWAVG 238
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 93.5 bits (222), Expect = 1e-18
Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 10/209 (4%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 475
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLX 835
A+ +H GI+HRDLKP N+LL+ D KI DFG + L ++ TL
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 836 GSPMYMXPXXIMSLKIXA---KXXLWSLG 913
G+P Y+ P ++S+ WSLG
Sbjct: 386 GTPTYLAPEVLVSVGTAGYNRAVDCWSLG 414
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 93.5 bits (222), Expect = 1e-18
Identities = 60/195 (30%), Positives = 99/195 (50%), Gaps = 3/195 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ---HKNL 508
+G G FA+V K R+ K+ A K + KK +AS V +I RE++ L+ H N+
Sbjct: 29 LGSGQFAIVKKCRE-KSTGLEYAAKFI-KKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
Query: 509 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
+ +HD ++ V +++E +GG+L D+L LSE F+ Q+ + ++ +H K I
Sbjct: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIA 146
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXI 868
H DLKP NI+L L P P K+ DFG + G + G+P ++ P +
Sbjct: 147 HFDLKPENIML----LDKNIPIPH---IKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV 199
Query: 869 MSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 200 NYEPLGLEADMWSIG 214
>AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 312
Score = 93.5 bits (222), Expect = 1e-18
Identities = 62/196 (31%), Positives = 98/196 (50%), Gaps = 3/196 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXX 865
HRD+K NI LT + L K+ D+G + L +M TL G+P YM P
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
Query: 866 IMSLKIXAKXXLWSLG 913
+K K +W++G
Sbjct: 223 CQGVKYNFKSDIWAVG 238
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 93.5 bits (222), Expect = 1e-18
Identities = 62/196 (31%), Positives = 98/196 (50%), Gaps = 3/196 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 89 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 145
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 146 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 205
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXX 865
HRD+K NI LT + L K+ D+G + L +M TL G+P YM P
Sbjct: 206 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 254
Query: 866 IMSLKIXAKXXLWSLG 913
+K K +W++G
Sbjct: 255 CQGVKYNFKSDIWAVG 270
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 93.5 bits (222), Expect = 1e-18
Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G K + VAVK++ ++ I ++ +++ K + ++
Sbjct: 13 VKIGHYILG--DTLGVGTFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQ 68
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P+ +++VMEY +GG+L DY+ N L E + Q+
Sbjct: 69 NLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSG 128
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 129 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 177
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 178 SPNYAAPEVISGRLYAGPEVDIWSSG 203
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 93.5 bits (222), Expect = 1e-18
Identities = 60/195 (30%), Positives = 99/195 (50%), Gaps = 3/195 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ---HKNL 508
+G G FA+V K R+ K+ A K + KK +AS V +I RE++ L+ H N+
Sbjct: 29 LGSGQFAIVKKCRE-KSTGLEYAAKFI-KKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
Query: 509 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
+ +HD ++ V +++E +GG+L D+L LSE F+ Q+ + ++ +H K I
Sbjct: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIA 146
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXI 868
H DLKP NI+L L P P K+ DFG + G + G+P ++ P +
Sbjct: 147 HFDLKPENIML----LDKNIPIPH---IKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV 199
Query: 869 MSLKIXAKXXLWSLG 913
+ + +WS+G
Sbjct: 200 NYEPLGLEADMWSIG 214
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 92.7 bits (220), Expect = 2e-18
Identities = 63/205 (30%), Positives = 100/205 (48%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
VG+Y + IG G A V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNSAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL ++ KI DFGF G+ T GS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 219 PPYAAPELFQGKKYDGPEVDIWSLG 243
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 92.7 bits (220), Expect = 2e-18
Identities = 63/205 (30%), Positives = 100/205 (48%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
VG+Y + IG G A V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNSAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
H K IVHRDLK N+LL ++ KI DFGF G+ T GS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
P Y P K + +WSLG
Sbjct: 219 PPYAAPELFQGKKYDGPEVDIWSLG 243
>Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta
protein.
Length = 584
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 239 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 297
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 298 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 356
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 357 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 405
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 406 TPNYIAPEILRGEEYGFSVDWWALG 430
>BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 414 TPNYIAPEILRGEEYGFSVDWWALG 438
>BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 414 TPNYIAPEILRGEEYGFSVDWWALG 438
>BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 414 TPNYIAPEILRGEEYGFSVDWWALG 438
>AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 414 TPNYIAPEILRGEEYGFSVDWWALG 438
>AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 414 TPNYIAPEILRGEEYGFSVDWWALG 438
>AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 414 TPNYIAPEILRGEEYGFSVDWWALG 438
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 91.9 bits (218), Expect = 4e-18
Identities = 65/202 (32%), Positives = 103/202 (50%), Gaps = 10/202 (4%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKILRELTALQ 496
+G GA V +RK + VA+K+++K+ I A E + EI+IL++L
Sbjct: 5 LGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLN--- 60
Query: 497 HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHA 676
H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+ A+ +H
Sbjct: 61 HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHE 119
Query: 677 KGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMX 856
GI+HRDLKP N+LL+ D KI DFG + L ++ TL G+P Y+
Sbjct: 120 NGIIHRDLKPENVLLSSQ--------EEDCLIKITDFGHSKILGETSLMRTLCGTPTYLA 171
Query: 857 PXXIMSLKIXA---KXXLWSLG 913
P ++S+ WSLG
Sbjct: 172 PEVLVSVGTAGYNRAVDCWSLG 193
>L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta
protein.
Length = 592
Score = 91.5 bits (217), Expect = 5e-18
Identities = 63/205 (30%), Positives = 105/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G +A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGTYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL +D K+ D+G + L G+ T G
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + + W+LG
Sbjct: 414 TPNYIAPEILRGEEYGFSVDWWALG 438
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 91.5 bits (217), Expect = 5e-18
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 2/206 (0%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILR 478
++G YE + IG G FA+V + ++ VA+K++ K + + + + + +E++I++
Sbjct: 4 RIGYYEIDRT--IGKGNFAVVKRATHLVTKAK-VAIKIIDKTQLDEENLKKIFREVQIMK 60
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L H +++ ++ M++ +Y+V EY +GG++ D+L + ++E + Q+ A
Sbjct: 61 MLC---HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTA 117
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H + IVHRDLK N+LL +++ KI DFGF G + T G
Sbjct: 118 VYFCHCRNIVHRDLKAENLLL-----------DANLNIKIADFGFSNLFTPGQLLKTWCG 166
Query: 839 SPMYMXPXXIMSLKIXA-KXXLWSLG 913
SP Y P + K +WSLG
Sbjct: 167 SPPYAAPELFEGKEYDGPKVDIWSLG 192
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 91.5 bits (217), Expect = 5e-18
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 2/206 (0%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILR 478
++G YE + IG G FA+V + ++ VA+K++ K + + + + + +E++I++
Sbjct: 112 RIGYYEIDRT--IGKGNFAVVKRATHLVTKAK-VAIKIIDKTQLDEENLKKIFREVQIMK 168
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L H +++ ++ M++ +Y+V EY +GG++ D+L + ++E + Q+ A
Sbjct: 169 MLC---HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTA 225
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H + IVHRDLK N+LL +++ KI DFGF G + T G
Sbjct: 226 VYFCHCRNIVHRDLKAENLLL-----------DANLNIKIADFGFSNLFTPGQLLKTWCG 274
Query: 839 SPMYMXPXXIMSLKIXA-KXXLWSLG 913
SP Y P + K +WSLG
Sbjct: 275 SPPYAAPELFEGKEYDGPKVDIWSLG 300
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 90.6 bits (215), Expect = 9e-18
Identities = 55/190 (28%), Positives = 95/190 (50%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G K + VAVK++ ++ I ++ +++ K + ++
Sbjct: 13 VKIGHYILG--DTLGVGTFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQ 68
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P+ +++VMEY +GG+L DY+ N L E + Q+
Sbjct: 69 NLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSG 128
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 129 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 177
Query: 839 SPMYMXPXXI 868
SP Y P I
Sbjct: 178 SPNYAAPEVI 187
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 90.6 bits (215), Expect = 9e-18
Identities = 62/208 (29%), Positives = 104/208 (50%), Gaps = 3/208 (1%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 475
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 22 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 78
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 79 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 135
Query: 656 AMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXK-IXDFGFXRFLXXGNMXVTL 832
A+ H IVHRDLK N+LL ++ DI DFGF F G T
Sbjct: 136 AVEYCHDHHIVHRDLKTENLLLDGNM---------DIKLAGTEDFGFGNFYKSGEPLSTW 186
Query: 833 XGSPMYMXPXXIMSLKIXA-KXXLWSLG 913
GSP Y P + + +WSLG
Sbjct: 187 CGSPPYAAPEVFEGKEYEGPQLDIWSLG 214
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 90.6 bits (215), Expect = 9e-18
Identities = 62/210 (29%), Positives = 102/210 (48%), Gaps = 4/210 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRE 481
+VG+Y + + G G+FA V +G + VA+KV+ KK +K + + K ++ +
Sbjct: 57 RVGNYLIGSRKL-GEGSFAKVREGLHVLT-GEKVAIKVIDKKRAKKDTYV-TKNLRREGQ 113
Query: 482 LTAL-QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
+ + +H N+ + D +++ Y+VME C GG+L + + L E+ + ++ QL A
Sbjct: 114 IQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISA 173
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR---FLXXGNMXVT 829
+ +H G+VHRDLK N+LL D K+ DFG L + T
Sbjct: 174 VEHLHRAGVVHRDLKIENLLL-----------DEDNNIKLIDFGLSNCAGILGYSDPFST 222
Query: 830 LXGSPMYMXPXXIMSLKIXAKXXLWSLGXN 919
GSP Y P + K K +WS+G N
Sbjct: 223 QCGSPAYAAPELLARKKYGPKIDVWSIGVN 252
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 90.2 bits (214), Expect = 1e-17
Identities = 59/194 (30%), Positives = 94/194 (48%), Gaps = 2/194 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI-QKASEILVKEIKILRELTALQHKNLVA 514
IG G F+ V G + VA+K++ K + QK +L +EI + +L H N++
Sbjct: 80 IGSGNFSQVKLGIHSLT-KEKVAIKILDKTKLDQKTQRLLSREISSMEKL---HHPNIIR 135
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 694
+++ +++ + +++VMEY GG+L + T LSE +L +Q+ A+ +H I+HR
Sbjct: 136 LYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHR 195
Query: 695 DLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMS 874
DLK N+ T S+ K+ DFGF G M T GSP Y P
Sbjct: 196 DLKAENVFYT-----------SNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRD 244
Query: 875 LK-IXAKXXLWSLG 913
I +W+LG
Sbjct: 245 EHYIGIYVDIWALG 258
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 359 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 416
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 477 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 525
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 526 APEIILNKGHDISADYWSLG 545
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/187 (29%), Positives = 93/187 (49%), Gaps = 1/187 (0%)
Frame = +2
Query: 347 GAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAMHDC 526
GAF V G K + VAVK++ ++ I ++ +++ K + ++ L +H +++ ++
Sbjct: 1 GAFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQNLKLFRHPHIIKLYQV 58
Query: 527 MDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRDLKP 706
+ +P+ +++VMEY +GG+L DY+ N L E + Q+ + H +VHRDLKP
Sbjct: 59 ISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKP 118
Query: 707 XNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMS-LKI 883
N+LL + + KI DFG + G T GSP Y P I L +
Sbjct: 119 ENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYV 167
Query: 884 XAKXXLW 904
+ LW
Sbjct: 168 GPEVDLW 174
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 359 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 416
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 477 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 525
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 526 APEIILNKGHDISADYWSLG 545
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 514 APEIILNKGHDISADYWSLG 533
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 514 APEIILNKGHDISADYWSLG 533
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 514 APEIILNKGHDISADYWSLG 533
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+KGI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 514 APEIILNKGHDISADYWSLG 533
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 89.4 bits (212), Expect = 2e-17
Identities = 59/198 (29%), Positives = 98/198 (49%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP + I DFG + G M T G+P Y+ P
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 189 EVLAQKPYSKAVDCWSIG 206
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 89.4 bits (212), Expect = 2e-17
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 179
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K K +WS G
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCG 203
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 89.4 bits (212), Expect = 2e-17
Identities = 59/198 (29%), Positives = 98/198 (49%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP + I DFG + G M T G+P Y+ P
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 189 EVLAQKPYSKAVDCWSIG 206
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 89.4 bits (212), Expect = 2e-17
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 179
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K K +WS G
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCG 203
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 89 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 144
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 145 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 204
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 205 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 255
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 256 GYGLKVDIWAAG 267
>AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 562
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 563 GYGLKVDIWAAG 574
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 89.4 bits (212), Expect = 2e-17
Identities = 59/198 (29%), Positives = 98/198 (49%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 28 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 82
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 83 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 142
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP + I DFG + G M T G+P Y+ P
Sbjct: 143 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 193
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 194 EVLAQKPYSKAVDCWSIG 211
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 89.4 bits (212), Expect = 2e-17
Identities = 59/198 (29%), Positives = 98/198 (49%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP + I DFG + G M T G+P Y+ P
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 189 EVLAQKPYSKAVDCWSIG 206
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 89.4 bits (212), Expect = 2e-17
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 179
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K K +WS G
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCG 203
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 89.4 bits (212), Expect = 2e-17
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 179
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K K +WS G
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCG 203
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 89.4 bits (212), Expect = 2e-17
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 179
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K K +WS G
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCG 203
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 89.4 bits (212), Expect = 2e-17
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 179
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K K +WS G
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCG 203
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 89.4 bits (212), Expect = 2e-17
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 179
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K K +WS G
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCG 203
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 89.4 bits (212), Expect = 2e-17
Identities = 59/198 (29%), Positives = 98/198 (49%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 680 GIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXP 859
GIVHRDLKP N+L TP + I DFG + G M T G+P Y+ P
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 860 XXIMSLKIXAKXXLWSLG 913
+ WS+G
Sbjct: 189 EVLAQKPYSKAVDCWSIG 206
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 89.4 bits (212), Expect = 2e-17
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 461 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 516
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 517 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 576
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP N+L+ + K+ DFG + T+ G+P Y+ P I
Sbjct: 577 IKPENLLVYEH-------QDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAET 627
Query: 878 KIXAKXXLWSLG 913
K +W+ G
Sbjct: 628 GYGLKVDIWAAG 639
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 89.0 bits (211), Expect = 3e-17
Identities = 68/201 (33%), Positives = 100/201 (49%), Gaps = 1/201 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSPMY 850
++G+VHRDLKP NIL R S + ++ DFGF + L GN + +T + +
Sbjct: 525 SQGVVHRDLKPSNIL-------YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
+ P + A +WSLG
Sbjct: 578 VAPEVLKRQGYDAACDIWSLG 598
Score = 77.4 bits (182), Expect = 9e-14
Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 487
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 668 IHAKGIVHRDLKPXNILL 721
+H+ GI++RDLKP NILL
Sbjct: 175 LHSLGIIYRDLKPENILL 192
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 89.0 bits (211), Expect = 3e-17
Identities = 68/201 (33%), Positives = 100/201 (49%), Gaps = 1/201 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSPMY 850
++G+VHRDLKP NIL R S + ++ DFGF + L GN + +T + +
Sbjct: 525 SQGVVHRDLKPSNIL-------YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
+ P + A +WSLG
Sbjct: 578 VAPEVLKRQGYDAACDIWSLG 598
Score = 77.4 bits (182), Expect = 9e-14
Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 487
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 668 IHAKGIVHRDLKPXNILL 721
+H+ GI++RDLKP NILL
Sbjct: 175 LHSLGIIYRDLKPENILL 192
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/206 (27%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 176 SPNYTAPEVISGRLYAGPEVDIWSCG 201
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 89.0 bits (211), Expect = 3e-17
Identities = 62/205 (30%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +K + A+KVV K+ + +I V+ K + E
Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKT-DRIYAMKVVKKELVNDDEDIDWVQTEKHVFE 298
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A H LV +H C + + ++ V+EY NGGDL ++Q R L E + + A+++ A+
Sbjct: 299 -QASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLAL 357
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL S+ K+ D+G + L G+ T G
Sbjct: 358 NYLHERGIIYRDLKLDNVLL-----------DSEGHIKLTDYGMCKEGLRPGDTTSTFCG 406
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + W+LG
Sbjct: 407 TPNYIAPEILRGEDYGFSVDWWALG 431
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 89.0 bits (211), Expect = 3e-17
Identities = 62/205 (30%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +K + A+KVV K+ + +I V+ K + E
Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKT-DRIYAMKVVKKELVNDDEDIDWVQTEKHVFE 298
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A H LV +H C + + ++ V+EY NGGDL ++Q R L E + + A+++ A+
Sbjct: 299 -QASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLAL 357
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL S+ K+ D+G + L G+ T G
Sbjct: 358 NYLHERGIIYRDLKLDNVLL-----------DSEGHIKLTDYGMCKEGLRPGDTTSTFCG 406
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + W+LG
Sbjct: 407 TPNYIAPEILRGEDYGFSVDWWALG 431
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/206 (27%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVNIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCG 201
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/206 (27%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCG 201
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/206 (27%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCG 201
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/206 (27%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCG 201
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 89.0 bits (211), Expect = 3e-17
Identities = 62/205 (30%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 481
+G +F +IG G++A V R +K + A+KVV K+ + +I V+ K + E
Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKT-DRIYAMKVVKKELVNDDEDIDWVQTEKHVFE 298
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 661
A H LV +H C + + ++ V+EY NGGDL ++Q R L E + + A+++ A+
Sbjct: 299 -QASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLAL 357
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXG 838
+ +H +GI++RDLK N+LL S+ K+ D+G + L G+ T G
Sbjct: 358 NYLHERGIIYRDLKLDNVLL-----------DSEGHIKLTDYGMCKEGLRPGDTTSTFCG 406
Query: 839 SPMYMXPXXIMSLKIXAKXXLWSLG 913
+P Y+ P + W+LG
Sbjct: 407 TPNYIAPEILRGEDYGFSVDWWALG 431
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 89.0 bits (211), Expect = 3e-17
Identities = 68/201 (33%), Positives = 100/201 (49%), Gaps = 1/201 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSPMY 850
++G+VHRDLKP NIL R S + ++ DFGF + L GN + +T + +
Sbjct: 525 SQGVVHRDLKPSNIL-------YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
+ P + A +WSLG
Sbjct: 578 VAPEVLKRQGYDAACDIWSLG 598
Score = 77.4 bits (182), Expect = 9e-14
Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 487
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 668 IHAKGIVHRDLKPXNILL 721
+H+ GI++RDLKP NILL
Sbjct: 175 LHSLGIIYRDLKPENILL 192
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 89.0 bits (211), Expect = 3e-17
Identities = 60/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 31 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 85
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 86 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 145
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 146 FCHSYSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 194
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K + +WS G
Sbjct: 195 HYACPEVIKGEKYDGRRADMWSCG 218
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 89.0 bits (211), Expect = 3e-17
Identities = 60/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 31 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 85
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 86 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 145
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 146 FCHSYSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 194
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K + +WS G
Sbjct: 195 HYACPEVIKGEKYDGRRADMWSCG 218
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/206 (27%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXG 838
+ H +VHRDLKP N+LL + + KI DFG + G T G
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 839 SPMYMXPXXIMS-LKIXAKXXLWSLG 913
SP Y P I L + +WS G
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCG 201
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 89.0 bits (211), Expect = 3e-17
Identities = 68/201 (33%), Positives = 100/201 (49%), Gaps = 1/201 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSPMY 850
++G+VHRDLKP NIL R S + ++ DFGF + L GN + +T + +
Sbjct: 525 SQGVVHRDLKPSNIL-------YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
+ P + A +WSLG
Sbjct: 578 VAPEVLKRQGYDAACDIWSLG 598
Score = 77.4 bits (182), Expect = 9e-14
Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 487
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 668 IHAKGIVHRDLKPXNILL 721
+H+ GI++RDLKP NILL
Sbjct: 175 LHSLGIIYRDLKPENILL 192
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 89.0 bits (211), Expect = 3e-17
Identities = 60/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 31 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 85
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 86 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 145
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 146 FCHSYSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 194
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K + +WS G
Sbjct: 195 HYACPEVIKGEKYDGRRADMWSCG 218
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 89.0 bits (211), Expect = 3e-17
Identities = 60/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 47 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 101
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 102 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 161
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSP 844
H+ I HRDLKP N+LL ++I +I DFG ++ T GSP
Sbjct: 162 FCHSYSICHRDLKPENLLLDEK---------NNI--RIADFGMASLQVGDSLLETSCGSP 210
Query: 845 MYMXPXXIMSLKIXA-KXXLWSLG 913
Y P I K + +WS G
Sbjct: 211 HYACPEVIKGEKYDGRRADMWSCG 234
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 89.0 bits (211), Expect = 3e-17
Identities = 68/201 (33%), Positives = 100/201 (49%), Gaps = 1/201 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 488 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 537
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 538 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 597
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSPMY 850
++G+VHRDLKP NIL R S + ++ DFGF + L GN + +T + +
Sbjct: 598 SQGVVHRDLKPSNIL-------YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 650
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
+ P + A +WSLG
Sbjct: 651 VAPEVLKRQGYDAACDIWSLG 671
Score = 77.4 bits (182), Expect = 9e-14
Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 3/138 (2%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 487
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 131 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 190
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 191 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 247
Query: 668 IHAKGIVHRDLKPXNILL 721
+H+ GI++RDLKP NILL
Sbjct: 248 LHSLGIIYRDLKPENILL 265
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 88.6 bits (210), Expect = 4e-17
Identities = 60/203 (29%), Positives = 104/203 (51%), Gaps = 4/203 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELTA 490
+F +++G G+FA VY+ + VA+K++ KK + KA + + E+KI +L
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESI-HTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQL-- 67
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTN-RLLSETTIQLFLAQLAEAMSA 667
+H +++ +++ + YVY+V+E C+ G++ YL+ + SE + F+ Q+ M
Sbjct: 68 -KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSP 844
+H+ GI+HRDL N+LLT ++ KI DFG L + TL G+P
Sbjct: 127 LHSHGILHRDLTLSNLLLTR-----------NMNIKIADFGLATQLKMPHEKHYTLCGTP 175
Query: 845 MYMXPXXIMSLKIXAKXXLWSLG 913
Y+ P + +WSLG
Sbjct: 176 NYISPEIATRSAHGLESDVWSLG 198
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 88.6 bits (210), Expect = 4e-17
Identities = 60/203 (29%), Positives = 104/203 (51%), Gaps = 4/203 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELTA 490
+F +++G G+FA VY+ + VA+K++ KK + KA + + E+KI +L
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESI-HTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQL-- 67
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTN-RLLSETTIQLFLAQLAEAMSA 667
+H +++ +++ + YVY+V+E C+ G++ YL+ + SE + F+ Q+ M
Sbjct: 68 -KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSP 844
+H+ GI+HRDL N+LLT ++ KI DFG L + TL G+P
Sbjct: 127 LHSHGILHRDLTLSNLLLTR-----------NMNIKIADFGLATQLKMPHEKHYTLCGTP 175
Query: 845 MYMXPXXIMSLKIXAKXXLWSLG 913
Y+ P + +WSLG
Sbjct: 176 NYISPEIATRSAHGLESDVWSLG 198
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 88.6 bits (210), Expect = 4e-17
Identities = 60/203 (29%), Positives = 105/203 (51%), Gaps = 4/203 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELTA 490
+F +++G G+FA VY+ + + VA+K++ KK + KA + + E+KI +L
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHSGLE-VAIKMIDKKAMYKAGMVQRVQNEVKIHCQL-- 67
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTN-RLLSETTIQLFLAQLAEAMSA 667
+H +++ +++ + YVY+V+E C+ G++ YL+ + SE + F+ Q+ M
Sbjct: 68 -KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGSP 844
+H+ GI+HRDL N+LLT ++ KI DFG L + TL G+P
Sbjct: 127 LHSHGILHRDLTLSNLLLTR-----------NMNIKIADFGLATQLKMPHEKHYTLCGTP 175
Query: 845 MYMXPXXIMSLKIXAKXXLWSLG 913
Y+ P + +WSLG
Sbjct: 176 NYISPEIATRSAHGLESDVWSLG 198
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 88.2 bits (209), Expect = 5e-17
Identities = 53/174 (30%), Positives = 90/174 (51%), Gaps = 1/174 (0%)
Frame = +2
Query: 395 QSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNG 574
Q VA+K+V ++ + ++ +L+K + + L ++H +++ +HD ++ Y+Y+V+E+ +G
Sbjct: 89 QKVAIKIVNREKLSES--VLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 146
Query: 575 GDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPX 754
G+L DYL L+ + F Q+ A+ H+ I HRDLKP N+LL
Sbjct: 147 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEK-------- 198
Query: 755 PSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSLKIXA-KXXLWSLG 913
++I +I DFG ++ T GSP Y P I K K +WS G
Sbjct: 199 -NNI--RIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 249
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 88.2 bits (209), Expect = 5e-17
Identities = 55/203 (27%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELT 487
+ + Q+ +G G + V + +R + + VA+K + K I+ ++ + +EI+I+ +
Sbjct: 90 HRYELQETLGKGTYGKVKRATERFS-GRVVAIKSIRKDKIKDEQDMVHIRREIEIM---S 145
Query: 488 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 667
+L H +++++++ ++ + ++MEY + G+L DY+ R LSE + F Q+ A+
Sbjct: 146 SLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHY 205
Query: 668 IHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPM 847
H G+VHRDLK NILL + KI DFG T GSP+
Sbjct: 206 CHKNGVVHRDLKLENILL-----------DDNCNIKIADFGLSNLYQKDKFLQTFCGSPL 254
Query: 848 YMXPXXIMSLKIXA-KXXLWSLG 913
Y P + + W+LG
Sbjct: 255 YASPEIVNGRPYRGPEVDSWALG 277
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 87.8 bits (208), Expect = 6e-17
Identities = 54/200 (27%), Positives = 98/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 496
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 497 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYM 853
+ GI++RDLKP N++L H K+ DFGF + + G T G+P Y+
Sbjct: 492 SNGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 854 XPXXIMSLKIXAKXXLWSLG 913
P I++ WSLG
Sbjct: 541 APEIILNKGHDISADYWSLG 560
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 87.8 bits (208), Expect = 6e-17
Identities = 61/201 (30%), Positives = 98/201 (48%), Gaps = 5/201 (2%)
Frame = +2
Query: 326 KQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ--- 496
K +G G+F++ K +K+ +Q+ AVK+++K+ E +E+TAL+
Sbjct: 428 KDKPLGEGSFSICRKCVHKKS-NQAFAVKIISKR----------MEANTQKEITALKLCE 476
Query: 497 -HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H N+V +H+ + ++VME NGG+L + ++ + SET + +L A+S +H
Sbjct: 477 GHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV-TLXGSPMY 850
G+VHRDLKP N+L T ++ KI DFGF R N + T + Y
Sbjct: 537 DVGVVHRDLKPENLLFTDE--------NDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHY 588
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
P + LWSLG
Sbjct: 589 AAPELLNQNGYDESCDLWSLG 609
Score = 67.3 bits (157), Expect = 1e-10
Identities = 43/145 (29%), Positives = 78/145 (53%), Gaps = 5/145 (3%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGI-QKA--SEILVKEI 466
+VG F ++G GA+ V+ RK + + A+KV+ K I QKA +E E
Sbjct: 43 KVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTER 102
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
++L + Q LV +H + ++++++Y NGG+L +L +E +Q+++ +
Sbjct: 103 QVLEHIR--QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGE 160
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILL 721
+ A+ +H GI++RD+K NILL
Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILL 185
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 87.8 bits (208), Expect = 6e-17
Identities = 61/201 (30%), Positives = 98/201 (48%), Gaps = 5/201 (2%)
Frame = +2
Query: 326 KQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ--- 496
K +G G+F++ K +K+ +Q+ AVK+++K+ E +E+TAL+
Sbjct: 428 KDKPLGEGSFSICRKCVHKKS-NQAFAVKIISKR----------MEANTQKEITALKLCE 476
Query: 497 -HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H N+V +H+ + ++VME NGG+L + ++ + SET + +L A+S +H
Sbjct: 477 GHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV-TLXGSPMY 850
G+VHRDLKP N+L T ++ KI DFGF R N + T + Y
Sbjct: 537 DVGVVHRDLKPENLLFTDE--------NDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHY 588
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
P + LWSLG
Sbjct: 589 AAPELLNQNGYDESCDLWSLG 609
Score = 67.3 bits (157), Expect = 1e-10
Identities = 43/145 (29%), Positives = 78/145 (53%), Gaps = 5/145 (3%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGI-QKA--SEILVKEI 466
+VG F ++G GA+ V+ RK + + A+KV+ K I QKA +E E
Sbjct: 43 KVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTER 102
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
++L + Q LV +H + ++++++Y NGG+L +L +E +Q+++ +
Sbjct: 103 QVLEHIR--QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGE 160
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILL 721
+ A+ +H GI++RD+K NILL
Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILL 185
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 579
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 580 YTANFVAPEVLKRQGYDAACDIWSLG 605
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 185 HSLGIIYRDLKPENILL 201
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 579
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 580 YTANFVAPEVLKRQGYDAACDIWSLG 605
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 185 HSLGIIYRDLKPENILL 201
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 579
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 580 YTANFVAPEVLKRQGYDAACDIWSLG 605
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 185 HSLGIIYRDLKPENILL 201
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 579
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 580 YTANFVAPEVLKRQGYDAACDIWSLG 605
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 185 HSLGIIYRDLKPENILL 201
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 87.4 bits (207), Expect = 9e-17
Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG GAF Y + + + V ++ +K + E KE+ +L ++ +H N+VA
Sbjct: 10 IGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKM---KHPNIVAF 66
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNR--LLSETTIQLFLAQLAEAMSAIHAKGIVH 691
+ +++VMEYC+GGDL + R L SE I + Q++ + IH + I+H
Sbjct: 67 FNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILH 126
Query: 692 RDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXXI 868
RD+K NI L+ + + K+ DFG R L + T G+P Y+ P
Sbjct: 127 RDIKAQNIFLS----------KNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEIC 176
Query: 869 MSLKIXAKXXLWSLG 913
+ K +WSLG
Sbjct: 177 QNKPYNNKTDIWSLG 191
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 579
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 580 YTANFVAPEVLKRQGYDAACDIWSLG 605
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 185 HSLGIIYRDLKPENILL 201
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 579
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 580 YTANFVAPEVLKRQGYDAACDIWSLG 605
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 185 HSLGIIYRDLKPENILL 201
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 87.4 bits (207), Expect = 9e-17
Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG GAF Y + + + V ++ +K + E KE+ +L ++ +H N+VA
Sbjct: 10 IGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKM---KHPNIVAF 66
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNR--LLSETTIQLFLAQLAEAMSAIHAKGIVH 691
+ +++VMEYC+GGDL + R L SE I + Q++ + IH + I+H
Sbjct: 67 FNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILH 126
Query: 692 RDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPXXI 868
RD+K NI L+ + + K+ DFG R L + T G+P Y+ P
Sbjct: 127 RDIKAQNIFLS----------KNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEIC 176
Query: 869 MSLKIXAKXXLWSLG 913
+ K +WSLG
Sbjct: 177 QNKPYNNKTDIWSLG 191
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 variant protein.
Length = 806
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 482 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 533
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 534 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 592
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 593 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 645
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 646 YTANFVAPEVLKRQGYDAACDIWSLG 671
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 134 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 191
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 192 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 251
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 252 HSLGIIYRDLKPENILL 268
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 87.4 bits (207), Expect = 9e-17
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 299 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 478
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 402 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 453
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 454 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 512
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLX 835
+ +HA+G+VHRDLKP NIL + P I +I DFGF + L N + +T
Sbjct: 513 VEYLHAQGVVHRDLKPSNILYV-----DESGNPESI--RICDFGFAKQLRAENGLLMTPC 565
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ ++ P + A +WSLG
Sbjct: 566 YTANFVAPEVLKRQGYDAACDIWSLG 591
Score = 75.8 bits (178), Expect = 3e-13
Identities = 40/137 (29%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +2
Query: 317 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 490
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 53 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 110
Query: 491 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 670
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 111 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 170
Query: 671 HAKGIVHRDLKPXNILL 721
H+ GI++RDLKP NILL
Sbjct: 171 HSLGIIYRDLKPENILL 187
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 87.0 bits (206), Expect = 1e-16
Identities = 60/201 (29%), Positives = 97/201 (48%), Gaps = 5/201 (2%)
Frame = +2
Query: 326 KQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ--- 496
K +G G+F++ K +K+ +Q++ VK+++K+ E +E+TAL+
Sbjct: 428 KDKPLGEGSFSICRKCVHKKS-NQALQVKIISKR----------MEANTQKEITALKLCE 476
Query: 497 -HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 673
H N+V +H+ + ++VME NGG+L D L+ + SET + +L A+S +H
Sbjct: 477 GHPNIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMH 536
Query: 674 AKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMY- 850
G+VHRDLKP N+L T ++ KI DFGF R N + ++
Sbjct: 537 DLGVVHRDLKPENLLFTDE--------NDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHS 588
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
P + LWSLG
Sbjct: 589 CRPELLNQNGYDESCDLWSLG 609
Score = 67.3 bits (157), Expect = 1e-10
Identities = 43/145 (29%), Positives = 78/145 (53%), Gaps = 5/145 (3%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGI-QKA--SEILVKEI 466
+VG F ++G GA+ V+ RK + + A+KV+ K I QKA +E E
Sbjct: 43 KVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTER 102
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
++L + Q LV +H + ++++++Y NGG+L +L +E +Q+++ +
Sbjct: 103 QVLEHIR--QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGE 160
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILL 721
+ A+ +H GI++RD+K NILL
Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILL 185
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/205 (29%), Positives = 102/205 (49%), Gaps = 3/205 (1%)
Frame = +2
Query: 308 GDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQK-ASEILVKEIKILREL 484
G Y+ K +G G FA+V K + + VAVKV+ K + A+ L +E++ ++
Sbjct: 15 GLYDLDKT--LGRGHFAVV-KLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMK-- 69
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAM 661
+QH N+V +++ +D+ +Y+++E +GGD+ DY+ + L+E + + AQ+ A+
Sbjct: 70 -LVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 128
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
S H +VHRDLKP N++ K+ DFGF G T GS
Sbjct: 129 SYCHKLHVVHRDLKPENVVF----------FEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 178
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
Y P ++ + A +WSLG
Sbjct: 179 LAYSAPEILLGDEYDAPAVDIWSLG 203
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/205 (29%), Positives = 102/205 (49%), Gaps = 3/205 (1%)
Frame = +2
Query: 308 GDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQK-ASEILVKEIKILREL 484
G Y+ K +G G FA+V K + + VAVKV+ K + A+ L +E++ ++
Sbjct: 14 GLYDLDKT--LGRGHFAVV-KLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMK-- 68
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAM 661
+QH N+V +++ +D+ +Y+++E +GGD+ DY+ + L+E + + AQ+ A+
Sbjct: 69 -LVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
S H +VHRDLKP N++ K+ DFGF G T GS
Sbjct: 128 SYCHKLHVVHRDLKPENVVF----------FEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 177
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
Y P ++ + A +WSLG
Sbjct: 178 LAYSAPEILLGDEYDAPAVDIWSLG 202
>BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein.
Length = 501
Score = 86.6 bits (205), Expect = 1e-16
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 1/193 (0%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G+ +V R + + VAVK + + Q+ E+L E+ I+R+ QH+N+V M
Sbjct: 237 IGEGSTGIVCIATVRSS-GKLVAVKKMDLRK-QQRRELLFNEVVIMRDY---QHENVVEM 291
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
++ ++VVME+ GG L D + R+ E + LA L +A+S +HA+G++HRD
Sbjct: 292 YNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVL-QALSVLHAQGVIHRD 350
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGF-XRFLXXGNMXVTLXGSPMYMXPXXIMS 874
+K +ILLTH D K+ DFGF + +L G+P +M P I
Sbjct: 351 IKSDSILLTH-----------DGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISR 399
Query: 875 LKIXAKXXLWSLG 913
L + +WSLG
Sbjct: 400 LPYGPEVDIWSLG 412
>BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 86.6 bits (205), Expect = 1e-16
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 1/193 (0%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G+ +V R + + VAVK + + Q+ E+L E+ I+R+ QH+N+V M
Sbjct: 327 IGEGSTGIVCIATVRSS-GKLVAVKKMDLRK-QQRRELLFNEVVIMRDY---QHENVVEM 381
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
++ ++VVME+ GG L D + R+ E + LA L +A+S +HA+G++HRD
Sbjct: 382 YNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVL-QALSVLHAQGVIHRD 440
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGF-XRFLXXGNMXVTLXGSPMYMXPXXIMS 874
+K +ILLTH D K+ DFGF + +L G+P +M P I
Sbjct: 441 IKSDSILLTH-----------DGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISR 489
Query: 875 LKIXAKXXLWSLG 913
L + +WSLG
Sbjct: 490 LPYGPEVDIWSLG 502
>BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 86.6 bits (205), Expect = 1e-16
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 1/193 (0%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G+ +V R + + VAVK + + Q+ E+L E+ I+R+ QH+N+V M
Sbjct: 327 IGEGSTGIVCIATVRSS-GKLVAVKKMDLRK-QQRRELLFNEVVIMRDY---QHENVVEM 381
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
++ ++VVME+ GG L D + R+ E + LA L +A+S +HA+G++HRD
Sbjct: 382 YNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVL-QALSVLHAQGVIHRD 440
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGF-XRFLXXGNMXVTLXGSPMYMXPXXIMS 874
+K +ILLTH D K+ DFGF + +L G+P +M P I
Sbjct: 441 IKSDSILLTH-----------DGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISR 489
Query: 875 LKIXAKXXLWSLG 913
L + +WSLG
Sbjct: 490 LPYGPEVDIWSLG 502
>BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 426
Score = 86.6 bits (205), Expect = 1e-16
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 1/193 (0%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G+ +V R + + VAVK + + Q+ E+L E+ I+R+ QH+N+V M
Sbjct: 162 IGEGSTGIVCIATVRSS-GKLVAVKKMDLRK-QQRRELLFNEVVIMRDY---QHENVVEM 216
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
++ ++VVME+ GG L D + R+ E + LA L +A+S +HA+G++HRD
Sbjct: 217 YNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVL-QALSVLHAQGVIHRD 275
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGF-XRFLXXGNMXVTLXGSPMYMXPXXIMS 874
+K +ILLTH D K+ DFGF + +L G+P +M P I
Sbjct: 276 IKSDSILLTH-----------DGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISR 324
Query: 875 LKIXAKXXLWSLG 913
L + +WSLG
Sbjct: 325 LPYGPEVDIWSLG 337
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/205 (29%), Positives = 102/205 (49%), Gaps = 3/205 (1%)
Frame = +2
Query: 308 GDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQK-ASEILVKEIKILREL 484
G Y+ K +G G FA+V K + + VAVKV+ K + A+ L +E++ ++
Sbjct: 14 GLYDLDKT--LGRGHFAVV-KLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMK-- 68
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAM 661
+QH N+V +++ +D+ +Y+++E +GGD+ DY+ + L+E + + AQ+ A+
Sbjct: 69 -LVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
Query: 662 SAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGS 841
S H +VHRDLKP N++ K+ DFGF G T GS
Sbjct: 128 SYCHKLHVVHRDLKPENVVF----------FEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 177
Query: 842 PMYMXPXXIMSLKIXA-KXXLWSLG 913
Y P ++ + A +WSLG
Sbjct: 178 LAYSAPEILLGDEYDAPAVDIWSLG 202
>AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein.
Length = 591
Score = 86.6 bits (205), Expect = 1e-16
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 1/193 (0%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G+ +V R + + VAVK + + Q+ E+L E+ I+R+ QH+N+V M
Sbjct: 327 IGEGSTGIVCIATVRSS-GKLVAVKKMDLRK-QQRRELLFNEVVIMRDY---QHENVVEM 381
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
++ ++VVME+ GG L D + R+ E + LA L +A+S +HA+G++HRD
Sbjct: 382 YNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVL-QALSVLHAQGVIHRD 440
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGF-XRFLXXGNMXVTLXGSPMYMXPXXIMS 874
+K +ILLTH D K+ DFGF + +L G+P +M P I
Sbjct: 441 IKSDSILLTH-----------DGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISR 489
Query: 875 LKIXAKXXLWSLG 913
L + +WSLG
Sbjct: 490 LPYGPEVDIWSLG 502
>AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase
protein.
Length = 591
Score = 86.6 bits (205), Expect = 1e-16
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 1/193 (0%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G+ +V R + + VAVK + + Q+ E+L E+ I+R+ QH+N+V M
Sbjct: 327 IGEGSTGIVCIATVRSS-GKLVAVKKMDLRK-QQRRELLFNEVVIMRDY---QHENVVEM 381
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
++ ++VVME+ GG L D + R+ E + LA L +A+S +HA+G++HRD
Sbjct: 382 YNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVL-QALSVLHAQGVIHRD 440
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGF-XRFLXXGNMXVTLXGSPMYMXPXXIMS 874
+K +ILLTH D K+ DFGF + +L G+P +M P I
Sbjct: 441 IKSDSILLTH-----------DGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISR 489
Query: 875 LKIXAKXXLWSLG 913
L + +WSLG
Sbjct: 490 LPYGPEVDIWSLG 502
>AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein.
Length = 467
Score = 86.6 bits (205), Expect = 1e-16
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 1/193 (0%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G+ +V R + + VAVK + + Q+ E+L E+ I+R+ QH+N+V M
Sbjct: 203 IGEGSTGIVCIATVRSS-GKLVAVKKMDLRK-QQRRELLFNEVVIMRDY---QHENVVEM 257
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
++ ++VVME+ GG L D + R+ E + LA L +A+S +HA+G++HRD
Sbjct: 258 YNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVL-QALSVLHAQGVIHRD 316
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGF-XRFLXXGNMXVTLXGSPMYMXPXXIMS 874
+K +ILLTH D K+ DFGF + +L G+P +M P I
Sbjct: 317 IKSDSILLTH-----------DGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISR 365
Query: 875 LKIXAKXXLWSLG 913
L + +WSLG
Sbjct: 366 LPYGPEVDIWSLG 378
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 86.2 bits (204), Expect = 2e-16
Identities = 59/206 (28%), Positives = 99/206 (48%), Gaps = 3/206 (1%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILR 478
+ ++EF + ++G G+F V R K AVKV+ K I + ++ + E +IL
Sbjct: 352 IDNFEFIR--VLGKGSFGKVMLARV-KETGDLYAVKVLKKDVILQDDDVECTMTEKRILS 408
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
A H L + C +P ++ VME+ NGGDL ++Q +R E + + A++ A
Sbjct: 409 --LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISA 466
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLX 835
+ +H KGI++RDLK N+LL H + K+ DFG + + G T
Sbjct: 467 LMFLHDKGIIYRDLKLDNVLLDH-----------EGHCKLADFGMCKEGICNGVTTATFC 515
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
G+P Y+ P + + W++G
Sbjct: 516 GTPDYIAPEILQEMLYGPAVDWWAMG 541
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 60.1 bits (139), Expect(2) = 3e-16
Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +2
Query: 566 CNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRDLKPXNILLTHSILPXR 745
C G++ DYL ++ + E + Q+ A+ H K IVHRDLK N+LL
Sbjct: 168 CPAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLL-------- 219
Query: 746 TPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSLKIXA-KXXLWSLG 913
++ KI DFGF G+ T GSP Y P K + +WSLG
Sbjct: 220 ---DAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 273
Score = 46.0 bits (104), Expect(2) = 3e-16
Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 481
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 482 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGD 580
L H N+V + + +++ +Y+VMEY + G+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGE 142
>Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 85.0 bits (201), Expect = 5e-16
Identities = 52/141 (36%), Positives = 79/141 (56%), Gaps = 1/141 (0%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILR 478
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKESHIMAERSVL- 86
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A A
Sbjct: 87 -LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASA 145
Query: 659 MSAIHAKGIVHRDLKPXNILL 721
+ +H+ I++RDLKP NILL
Sbjct: 146 IGYLHSLNIIYRDLKPENILL 166
>Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 198
Score = 85.0 bits (201), Expect = 5e-16
Identities = 52/141 (36%), Positives = 79/141 (56%), Gaps = 1/141 (0%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILR 478
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKESHIMAERSVL- 86
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A A
Sbjct: 87 -LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASA 145
Query: 659 MSAIHAKGIVHRDLKPXNILL 721
+ +H+ I++RDLKP NILL
Sbjct: 146 IGYLHSLNIIYRDLKPENILL 166
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 85.0 bits (201), Expect = 5e-16
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 3/206 (1%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILR 478
+ ++EF + ++G G+F V R K AVKV+ K I ++ + E +IL
Sbjct: 351 IDNFEFIR--VLGKGSFGKVMLARV-KETGDLYAVKVLKKDVILLDDDVECTMTEKRILS 407
Query: 479 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 658
A H L + C +P ++ VME+ NGGDL ++Q +R E + + A++ A
Sbjct: 408 --LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISA 465
Query: 659 MSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLX 835
+ +H KGI++RDLK N+LL H + K+ DFG + + G T
Sbjct: 466 LMFLHDKGIIYRDLKLDNVLLDH-----------EGHCKLADFGMCKEGICNGVTTATFC 514
Query: 836 GSPMYMXPXXIMSLKIXAKXXLWSLG 913
G+P Y+ P + + W++G
Sbjct: 515 GTPDYIAPEILQEMLYGPAVDWWAMG 540
>BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein.
Length = 795
Score = 85.0 bits (201), Expect = 5e-16
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 1/211 (0%)
Frame = +2
Query: 284 VKMEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKE 463
VK I G YE + +++G G F V++ + K+ +A K++ K K E + E
Sbjct: 480 VKETSISAG-YEVCQHEVLGGGRFGQVHRCTE-KSTGLPLAAKIIKVKSA-KDREDVKNE 536
Query: 464 IKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFL 640
I I+ +L+ H NL+ ++D +S +VMEY +GG+L D + + L+E + LF
Sbjct: 537 INIMNQLS---HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFT 593
Query: 641 AQLAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNM 820
Q+ E + +H I+H DLKP NIL + + KI DFG R
Sbjct: 594 RQICEGVHYLHQHYILHLDLKPENILCVNQ---------TGHQIKIIDFGLARRYKPREK 644
Query: 821 XVTLXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
G+P ++ P + + +WS+G
Sbjct: 645 LKVNFGTPEFLAPEVVNYEFVSFPTDMWSVG 675
>AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kinase
(MLCK) protein.
Length = 795
Score = 85.0 bits (201), Expect = 5e-16
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 1/211 (0%)
Frame = +2
Query: 284 VKMEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKE 463
VK I G YE + +++G G F V++ + K+ +A K++ K K E + E
Sbjct: 480 VKETSISAG-YEVCQHEVLGGGRFGQVHRCTE-KSTGLPLAAKIIKVKSA-KDREDVKNE 536
Query: 464 IKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFL 640
I I+ +L+ H NL+ ++D +S +VMEY +GG+L D + + L+E + LF
Sbjct: 537 INIMNQLS---HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFT 593
Query: 641 AQLAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNM 820
Q+ E + +H I+H DLKP NIL + + KI DFG R
Sbjct: 594 RQICEGVHYLHQHYILHLDLKPENILCVNQ---------TGHQIKIIDFGLARRYKPREK 644
Query: 821 XVTLXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
G+P ++ P + + +WS+G
Sbjct: 645 LKVNFGTPEFLAPEVVNYEFVSFPTDMWSVG 675
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 192 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 246
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 307 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 355
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 356 PEYLAPEVLHKQPYDRTVDWWCLG 379
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 261 PEYLAPEVLHKQPYDRTVDWWCLG 284
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 261 PEYLAPEVLHKQPYDRTVDWWCLG 284
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 192 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 246
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 307 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 355
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 356 PEYLAPEVLHKQPYDRTVDWWCLG 379
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 192 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 246
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 307 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 355
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 356 PEYLAPEVLHKQPYDRTVDWWCLG 379
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 111 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 165
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 166 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 225
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 226 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 274
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 275 PEYLAPEVLHKQPYDRTVDWWCLG 298
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 261 PEYLAPEVLHKQPYDRTVDWWCLG 284
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 87 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 141
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 142 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 201
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 202 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 250
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 251 PEYLAPEVLHKQPYDRTVDWWCLG 274
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 261 PEYLAPEVLHKQPYDRTVDWWCLG 284
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 84.6 bits (200), Expect = 6e-16
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 311 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 484
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXR-FLXXGNMXVTLXGS 841
+H+ IV+RDLKP NILL S + DFG + + + T G+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 842 PMYMXPXXIMSLKIXAKXXLWSLG 913
P Y+ P + W LG
Sbjct: 261 PEYLAPEVLHKQPYDRTVDWWCLG 284
>X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase
protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase gamma
protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein.
Length = 387
Score = 84.2 bits (199), Expect = 8e-16
Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +2
Query: 314 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 466
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 467 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 646
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 647 LAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXV 826
L E + +H IVHRDLKP NILL ++ K+ DFGF L G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 827 TLXGSPMYMXPXXI 868
+ G+P Y+ P I
Sbjct: 183 EVCGTPSYLAPEII 196
>Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 146 AIGYLHSLNIIYRDLKPENILL 167
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 91 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 147
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 148 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 205
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 206 AIGYLHSLNIIYRDLKPENILL 227
>L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine
kinase protein.
Length = 841
Score = 83.8 bits (198), Expect = 1e-15
Identities = 57/197 (28%), Positives = 94/197 (47%), Gaps = 4/197 (2%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G G++ V + R++ Q V K+ + + +E ++L +L +H N+V
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL---KHPNIVT 67
Query: 515 MHDCMDS-PAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGI 685
+ + +Y+VM +C GGDL L Q +LL E + + Q+A A+ +H K I
Sbjct: 68 YKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHI 127
Query: 686 VHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPX 862
+HRDLK N+ LT + + K+ D G R L +M TL G+P YM P
Sbjct: 128 LHRDLKTQNVFLTRTNI-----------IKVGDLGIARVLENHCDMASTLIGTPYYMSPE 176
Query: 863 XIMSLKIXAKXXLWSLG 913
+ K +W+LG
Sbjct: 177 LFSNKPYNYKSDVWALG 193
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 146 AIDYLHSLNIIYRDLKPENILL 167
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 146 AIGYLHSLNIIYRDLKPENILL 167
>BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein.
Length = 781
Score = 83.8 bits (198), Expect = 1e-15
Identities = 57/197 (28%), Positives = 94/197 (47%), Gaps = 4/197 (2%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G G++ V + R++ Q V K+ + + +E ++L +L +H N+V
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL---KHPNIVT 67
Query: 515 MHDCMDS-PAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGI 685
+ + +Y+VM +C GGDL L Q +LL E + + Q+A A+ +H K I
Sbjct: 68 YKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHI 127
Query: 686 VHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPX 862
+HRDLK N+ LT + + K+ D G R L +M TL G+P YM P
Sbjct: 128 LHRDLKTQNVFLTRTNI-----------IKVGDLGIARVLENHCDMASTLIGTPYYMSPE 176
Query: 863 XIMSLKIXAKXXLWSLG 913
+ K +W+LG
Sbjct: 177 LFSNKPYNYKSDVWALG 193
>BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for
IMAGE:3913546) protein.
Length = 451
Score = 83.8 bits (198), Expect = 1e-15
Identities = 57/197 (28%), Positives = 94/197 (47%), Gaps = 4/197 (2%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G G++ V + R++ Q V K+ + + +E ++L +L +H N+V
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL---KHPNIVT 67
Query: 515 MHDCMDS-PAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGI 685
+ + +Y+VM +C GGDL L Q +LL E + + Q+A A+ +H K I
Sbjct: 68 YKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHI 127
Query: 686 VHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXG-NMXVTLXGSPMYMXPX 862
+HRDLK N+ LT + + K+ D G R L +M TL G+P YM P
Sbjct: 128 LHRDLKTQNVFLTRTNI-----------IKVGDLGIARVLENHCDMASTLIGTPYYMSPE 176
Query: 863 XIMSLKIXAKXXLWSLG 913
+ K +W+LG
Sbjct: 177 LFSNKPYNYKSDVWALG 193
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 146 AIGYLHSLNIIYRDLKPENILL 167
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 57 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 113
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 114 --LKNVRHPFLVGLRYSFQTPEELYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 171
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 172 AIGYLHSLNIIYRDLKPENILL 193
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 83.8 bits (198), Expect = 1e-15
Identities = 51/192 (26%), Positives = 92/192 (47%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G F V K + K A K + + +A ++I L AL H + +
Sbjct: 1090 IGRGVFGFV-KRVQHKGNKILCAAKFIPLRSRTRAQAYRERDI-----LAALSHPLVTGL 1143
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
D ++ + +++E C+ +L D L +++E +++++ QL E + +H+ G++H D
Sbjct: 1144 LDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYIQQLVEGLHYLHSHGVLHLD 1203
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP NIL+ H P DI KI DFGF + + + + GSP ++ P I
Sbjct: 1204 IKPSNILMVH-------PAREDI--KICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQN 1254
Query: 878 KIXAKXXLWSLG 913
+ +W++G
Sbjct: 1255 PVSEASDIWAMG 1266
Score = 55.6 bits (128), Expect = 3e-07
Identities = 34/135 (25%), Positives = 73/135 (54%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F Q I G F++V + ++ + +++A K++ K + +++E + L+ L+H
Sbjct: 2288 FAFQTQIQRGRFSVVRQCWEKAS-GRALAAKIIPYHPKDKTA--VLREYEALK---GLRH 2341
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+L +H SP ++ +++E C+G +L L SE+ ++ +L Q+ A +H +
Sbjct: 2342 PHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQMLSATQYLHNQ 2401
Query: 680 GIVHRDLKPXNILLT 724
I+H DL+ N+++T
Sbjct: 2402 HILHLDLRSENMIIT 2416
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 83.8 bits (198), Expect = 1e-15
Identities = 51/192 (26%), Positives = 92/192 (47%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G F V K + K A K + + +A ++I L AL H + +
Sbjct: 1090 IGRGVFGFV-KRVQHKGNKILCAAKFIPLRSRTRAQAYRERDI-----LAALSHPLVTGL 1143
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
D ++ + +++E C+ +L D L +++E +++++ QL E + +H+ G++H D
Sbjct: 1144 LDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYIQQLVEGLHYLHSHGVLHLD 1203
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP NIL+ H P DI KI DFGF + + + + GSP ++ P I
Sbjct: 1204 IKPSNILMVH-------PAREDI--KICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQN 1254
Query: 878 KIXAKXXLWSLG 913
+ +W++G
Sbjct: 1255 PVSEASDIWAMG 1266
Score = 55.6 bits (128), Expect = 3e-07
Identities = 34/135 (25%), Positives = 73/135 (54%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F Q I G F++V + ++ + +++A K++ K + +++E + L+ L+H
Sbjct: 2288 FAFQTQIQRGRFSVVRQCWEKAS-GRALAAKIIPYHPKDKTA--VLREYEALK---GLRH 2341
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+L +H SP ++ +++E C+G +L L SE+ ++ +L Q+ A +H +
Sbjct: 2342 PHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQMLSATQYLHNQ 2401
Query: 680 GIVHRDLKPXNILLT 724
I+H DL+ N+++T
Sbjct: 2402 HILHLDLRSENMIIT 2416
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 83.8 bits (198), Expect = 1e-15
Identities = 63/207 (30%), Positives = 100/207 (48%), Gaps = 4/207 (1%)
Frame = +2
Query: 305 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 484
V Y KQ IG G FA+VY+ + + A KVV K G+ K + L K + +R
Sbjct: 36 VDRYRVGKQ--IGKGGFAIVYELTSIRT-GKKYAGKVVEKAGLTKP-KYLEKFMSEIRIH 91
Query: 485 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 664
+L H ++ M+ + Y Y+++E C+ LA L+ L+E +Q FL Q+ +A+S
Sbjct: 92 QSLDHPHICKMYKHFEDNRYHYLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVS 151
Query: 665 AIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGN-MXVTLXGS 841
+H + I+HRDLK NI L ++ K+ D G L N T+ G+
Sbjct: 152 YLHKRCIIHRDLKLGNIFL-----------DENLEVKVGDLGLAAQLNEPNERKKTMCGT 200
Query: 842 PMYMXPXXIMSLKIXA---KXXLWSLG 913
P Y+ P + S A + +W++G
Sbjct: 201 PNYIAPEILQSNDKRAYSYEVDIWAVG 227
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 91 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 147
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 148 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 205
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 206 AIGYLHSLNIIYRDLKPENILL 227
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 83.8 bits (198), Expect = 1e-15
Identities = 52/142 (36%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Frame = +2
Query: 302 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 475
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 476 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 655
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 656 AMSAIHAKGIVHRDLKPXNILL 721
A+ +H+ I++RDLKP NILL
Sbjct: 146 AIGYLHSLNIIYRDLKPENILL 167
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 83.8 bits (198), Expect = 1e-15
Identities = 51/192 (26%), Positives = 92/192 (47%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 517
IG G F V K + K A K + + +A ++I L AL H + +
Sbjct: 1090 IGRGVFGFV-KRVQHKGNKILCAAKFIPLRSRTRAQAYRERDI-----LAALSHPLVTGL 1143
Query: 518 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 697
D ++ + +++E C+ +L D L +++E +++++ QL E + +H+ G++H D
Sbjct: 1144 LDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYIQQLVEGLHYLHSHGVLHLD 1203
Query: 698 LKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIMSL 877
+KP NIL+ H P DI KI DFGF + + + + GSP ++ P I
Sbjct: 1204 IKPSNILMVH-------PAREDI--KICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQN 1254
Query: 878 KIXAKXXLWSLG 913
+ +W++G
Sbjct: 1255 PVSEASDIWAMG 1266
Score = 55.6 bits (128), Expect = 3e-07
Identities = 34/135 (25%), Positives = 73/135 (54%)
Frame = +2
Query: 320 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 499
F Q I G F++V + ++ + +++A K++ K + +++E + L+ L+H
Sbjct: 2288 FAFQTQIQRGRFSVVRQCWEKAS-GRALAAKIIPYHPKDKTA--VLREYEALK---GLRH 2341
Query: 500 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 679
+L +H SP ++ +++E C+G +L L SE+ ++ +L Q+ A +H +
Sbjct: 2342 PHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQMLSATQYLHNQ 2401
Query: 680 GIVHRDLKPXNILLT 724
I+H DL+ N+++T
Sbjct: 2402 HILHLDLRSENMIIT 2416
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 83.4 bits (197), Expect = 1e-15
Identities = 60/194 (30%), Positives = 94/194 (48%), Gaps = 2/194 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILRELTALQHKNLV 511
+G G F V + K KN + + A+K + KK I K E + E +IL EL + +V
Sbjct: 459 LGVGGFGRV-ELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS---PFIV 514
Query: 512 AMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVH 691
++ YVY+++E C GG+L L+ E T + +A + EA +H GI++
Sbjct: 515 KLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIY 574
Query: 692 RDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIM 871
RDLKP N++L ++ K+ DFGF + + G T G+P Y+ P I+
Sbjct: 575 RDLKPENLIL-----------DAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVIL 623
Query: 872 SLKIXAKXXLWSLG 913
+ WSLG
Sbjct: 624 NKGHDFSVDFWSLG 637
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 83.4 bits (197), Expect = 1e-15
Identities = 60/194 (30%), Positives = 94/194 (48%), Gaps = 2/194 (1%)
Frame = +2
Query: 338 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILRELTALQHKNLV 511
+G G F V + K KN + + A+K + KK I K E + E +IL EL + +V
Sbjct: 459 LGVGGFGRV-ELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS---PFIV 514
Query: 512 AMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVH 691
++ YVY+++E C GG+L L+ E T + +A + EA +H GI++
Sbjct: 515 KLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIY 574
Query: 692 RDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXIM 871
RDLKP N++L ++ K+ DFGF + + G T G+P Y+ P I+
Sbjct: 575 RDLKPENLIL-----------DAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVIL 623
Query: 872 SLKIXAKXXLWSLG 913
+ WSLG
Sbjct: 624 NKGHDFSVDFWSLG 637
>BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 83.4 bits (197), Expect = 1e-15
Identities = 56/201 (27%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
Y +K +I+G G F V+K + +A K++ +G++ E+ EI ++ +L
Sbjct: 104 YTVSKTEILGGGRFGQVHKCEETAT-GLKLAAKIIKTRGMKDKEEVK-NEISVMNQL--- 158
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLAD-YLQTNRLLSETTIQLFLAQLAEAMSAI 670
H NL+ ++D +S + +VMEY +GG+L D + + L+E LF+ Q+ E + +
Sbjct: 159 DHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHM 218
Query: 671 HAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMY 850
H I+H DLKP NIL + KI DFG R G+P +
Sbjct: 219 HQMYILHLDLKPENILCVNR---------DAKQIKIIDFGLARRYKPREKLKVNFGTPEF 269
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
+ P + + +WS+G
Sbjct: 270 LAPEVVNYDFVSFPTDMWSVG 290
>BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 83.4 bits (197), Expect = 1e-15
Identities = 56/201 (27%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Frame = +2
Query: 314 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 493
Y +K +I+G G F V+K + +A K++ +G++ E+ EI ++ +L
Sbjct: 104 YTVSKTEILGGGRFGQVHKCEETAT-GLKLAAKIIKTRGMKDKEEVK-NEISVMNQL--- 158
Query: 494 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLAD-YLQTNRLLSETTIQLFLAQLAEAMSAI 670
H NL+ ++D +S + +VMEY +GG+L D + + L+E LF+ Q+ E + +
Sbjct: 159 DHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHM 218
Query: 671 HAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMY 850
H I+H DLKP NIL + KI DFG R G+P +
Sbjct: 219 HQMYILHLDLKPENILCVNR---------DAKQIKIIDFGLARRYKPREKLKVNFGTPEF 269
Query: 851 MXPXXIMSLKIXAKXXLWSLG 913
+ P + + +WS+G
Sbjct: 270 LAPEVVNYDFVSFPTDMWSVG 290
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 83.4 bits (197), Expect = 1e-15
Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 2/195 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF +V+ ++ + + ++ ++ ++ + E ++L+ L H N++
Sbjct: 9 VVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLK---LLNHPNVIE 65
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYLQT--NRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + MEY GG LA+++Q N LL E TI F Q+ A+ +H I+
Sbjct: 66 YYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLIL 125
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXI 868
HRDLK NILL + KI DFG + L + T+ G+P Y+ P
Sbjct: 126 HRDLKTQNILL----------DKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELC 175
Query: 869 MSLKIXAKXXLWSLG 913
K +W+LG
Sbjct: 176 EGKPYNQKSDIWALG 190
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 83.4 bits (197), Expect = 1e-15
Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 2/195 (1%)
Frame = +2
Query: 335 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 514
++G GAF +V+ ++ + + ++ ++ ++ + E ++L+ L H N++
Sbjct: 9 VVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLK---LLNHPNVIE 65
Query: 515 MHDCMDSPAYVYVVMEYCNGGDLADYLQT--NRLLSETTIQLFLAQLAEAMSAIHAKGIV 688
++ + + MEY GG LA+++Q N LL E TI F Q+ A+ +H I+
Sbjct: 66 YYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLIL 125
Query: 689 HRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLXXGNMXVTLXGSPMYMXPXXI 868
HRDLK NILL + KI DFG + L + T+ G+P Y+ P
Sbjct: 126 HRDLKTQNILL----------DKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELC 175
Query: 869 MSLKIXAKXXLWSLG 913
K +W+LG
Sbjct: 176 EGKPYNQKSDIWALG 190
>BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase
17a protein.
Length = 414
Score = 83.4 bits (197), Expect = 1e-15
Identities = 68/215 (31%), Positives = 105/215 (48%), Gaps = 4/215 (1%)
Frame = +2
Query: 281 LVKMEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTK--KGIQKASEIL 454
+V+ E Q G Y +G G FA+V K K K+ + A K + K KG EI
Sbjct: 49 VVRTEPFQDG-YSLCPGRELGRGKFAVVRKCIK-KDSGKEFAAKFMRKRRKGQDCRMEI- 105
Query: 455 VKEIKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR--LLSETTI 628
+ EI +L EL A + ++ +H+ ++ + + +V+EY GG++ D +R E +
Sbjct: 106 IHEIAVL-EL-AQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDV 163
Query: 629 QLFLAQLAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLX 808
Q + Q+ E + +H + +VH DLKP NILLT +P DI KI DFG R L
Sbjct: 164 QRLMRQILEGVHFLHTRDVVHLDLKPQNILLT-----SESPL-GDI--KIVDFGLSRILK 215
Query: 809 XGNMXVTLXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P Y+ P + I +WS+G
Sbjct: 216 NSEELREIMGTPEYVAPEILSYDPISMATDMWSIG 250
>BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase
17a protein.
Length = 414
Score = 83.4 bits (197), Expect = 1e-15
Identities = 68/215 (31%), Positives = 105/215 (48%), Gaps = 4/215 (1%)
Frame = +2
Query: 281 LVKMEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTK--KGIQKASEIL 454
+V+ E Q G Y +G G FA+V K K K+ + A K + K KG EI
Sbjct: 49 VVRTEPFQDG-YSLCPGRELGRGKFAVVRKCIK-KDSGKEFAAKFMRKRRKGQDCRMEI- 105
Query: 455 VKEIKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR--LLSETTI 628
+ EI +L EL A + ++ +H+ ++ + + +V+EY GG++ D +R E +
Sbjct: 106 IHEIAVL-EL-AQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDV 163
Query: 629 QLFLAQLAEAMSAIHAKGIVHRDLKPXNILLTHSILPXRTPXPSDITXKIXDFGFXRFLX 808
Q + Q+ E + +H + +VH DLKP NILLT +P DI KI DFG R L
Sbjct: 164 QRLMRQILEGVHFLHTRDVVHLDLKPQNILLT-----SESPL-GDI--KIVDFGLSRILK 215
Query: 809 XGNMXVTLXGSPMYMXPXXIMSLKIXAKXXLWSLG 913
+ G+P Y+ P + I +WS+G
Sbjct: 216 NSEELREIMGTPEYVAPEILSYDPISMATDMWSIG 250
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,095,396
Number of Sequences: 237096
Number of extensions: 2214964
Number of successful extensions: 13070
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 10538
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11101
length of database: 76,859,062
effective HSP length: 91
effective length of database: 55,283,326
effective search space used: 15976881214
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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