Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP25_F_D08
(1206 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 303 7e-81
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 294 3e-78
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 272 9e-72
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 249 1e-64
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 236 1e-60
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 213 1e-53
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 212 2e-53
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 192 2e-47
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 189 1e-46
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 185 2e-45
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 179 1e-43
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 177 4e-43
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 177 6e-43
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 176 8e-43
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 175 2e-42
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 173 8e-42
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 168 2e-40
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 168 2e-40
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 167 7e-40
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 165 3e-39
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 163 8e-39
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 161 3e-38
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 158 3e-37
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 156 9e-37
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 156 1e-36
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 153 1e-35
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 152 2e-35
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 148 2e-34
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 147 4e-34
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 147 4e-34
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 146 8e-34
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 146 1e-33
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 145 2e-33
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 144 5e-33
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 143 9e-33
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 142 1e-32
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 142 2e-32
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 142 2e-32
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 141 3e-32
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 141 3e-32
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 140 9e-32
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 139 1e-31
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 139 2e-31
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 138 4e-31
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 137 5e-31
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 137 6e-31
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 137 6e-31
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 137 6e-31
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 136 8e-31
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 136 1e-30
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 136 1e-30
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 135 2e-30
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 134 3e-30
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 134 4e-30
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 132 1e-29
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 132 2e-29
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 131 4e-29
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 130 5e-29
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 130 7e-29
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 130 9e-29
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 129 1e-28
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 129 2e-28
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 129 2e-28
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 127 7e-28
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 126 9e-28
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 126 1e-27
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 126 1e-27
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 126 2e-27
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 126 2e-27
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 125 3e-27
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 125 3e-27
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 123 1e-26
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 122 2e-26
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 122 2e-26
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 122 2e-26
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 120 6e-26
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 120 1e-25
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 120 1e-25
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 118 3e-25
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 117 7e-25
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 115 2e-24
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 114 4e-24
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 114 5e-24
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 113 7e-24
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 113 1e-23
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 112 2e-23
UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;... 112 2e-23
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 108 2e-22
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 107 4e-22
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 107 4e-22
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 107 7e-22
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 105 3e-21
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 104 5e-21
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 103 9e-21
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 102 2e-20
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 101 4e-20
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 101 4e-20
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 101 5e-20
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 100 7e-20
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 100 7e-20
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 100 7e-20
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 100 7e-20
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 100 9e-20
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 100 2e-19
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 99 3e-19
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 98 5e-19
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 96 2e-18
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 95 2e-18
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 95 2e-18
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 93 1e-17
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 93 2e-17
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 92 2e-17
UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k... 92 3e-17
UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil... 92 3e-17
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 91 7e-17
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 90 1e-16
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 89 2e-16
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 85 3e-15
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 82 3e-14
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 81 4e-14
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 81 4e-14
UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon... 81 7e-14
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 80 1e-13
UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker... 79 2e-13
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 79 2e-13
UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k... 79 3e-13
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 77 7e-13
UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ... 77 9e-13
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 77 9e-13
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 77 9e-13
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 73 1e-11
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 73 1e-11
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 72 3e-11
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 69 2e-10
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep... 68 4e-10
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije... 64 5e-09
UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 64 7e-09
UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 63 1e-08
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 62 3e-08
UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ... 61 6e-08
UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R... 61 6e-08
UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej... 57 1e-06
UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter... 56 1e-06
UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|... 54 7e-06
UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae... 54 1e-05
UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri... 54 1e-05
UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr... 53 1e-05
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 51 7e-05
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 49 3e-04
UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R... 48 6e-04
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 46 0.001
UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 46 0.002
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 45 0.003
UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba ... 44 0.010
UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267, w... 43 0.014
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 43 0.018
UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archae... 43 0.018
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 41 0.074
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 39 0.30
UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 38 0.52
UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep: CG1222... 38 0.69
UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_0023... 37 0.91
UniRef50_Q9LSA0 Cluster: Emb|CAB62463.1; n=3; Arabidopsis thalia... 37 1.2
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 36 2.1
UniRef50_A7EYT0 Cluster: Putative uncharacterized protein; n=1; ... 36 2.1
UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium c... 36 2.8
UniRef50_Q9RHY8 Cluster: ORF1 protein; n=1; Corynebacterium ammo... 35 4.8
UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding... 34 6.4
UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel... 34 8.5
>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Pyruvate kinase (PK) - Tribolium castaneum
Length = 557
Score = 303 bits (743), Expect = 7e-81
Identities = 142/241 (58%), Positives = 175/241 (72%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYH 406
+QL H LDI S +RL+G ICT GP++ +V L +E GMN+AR+ SHG+ E H
Sbjct: 32 TQLDHNSLLDIQSHPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMH 91
Query: 407 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 586
E I+N R A ++YS +LG + L++ALD KGPE+RTG +EGG +AEVELKKGE IKLTT
Sbjct: 92 TELIQNVRTAVENYSKRLGVMYPLSLALDIKGPEVRTGYMEGGIAAEVELKKGEQIKLTT 151
Query: 587 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLG 766
Y EKG++ IYVDY NI VV+PGNRIF+DDGLIS+IC SV LTC++ENGGMLG
Sbjct: 152 DKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICTSVQGSVLTCSVENGGMLG 211
Query: 767 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
S K VNLPGI +DLP VSEKDK DLLFGVE G+D + ASFIRN + E+R +LG G
Sbjct: 212 SCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDVLGRAGNK 271
Query: 947 I 949
I
Sbjct: 272 I 272
Score = 55.2 bits (127), Expect = 3e-06
Identities = 29/56 (51%), Positives = 37/56 (66%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXI-PXKRYPXPKNMIAKC 1101
G + IISK ENHQG+ N + II SDGIM+ RG L + I P K + K++IAKC
Sbjct: 269 GNKILIISKIENHQGVHNIDEIIKASDGIMIGRGDLAVEIGPEKLFLAQKSIIAKC 324
>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
nigroviridis|Rep: Pyruvate kinase - Tetraodon
nigroviridis (Green puffer)
Length = 569
Score = 294 bits (722), Expect = 3e-78
Identities = 144/247 (58%), Positives = 181/247 (73%), Gaps = 7/247 (2%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS + R +G ICT GPASR+V +L ++ GMN+AR+NFSHG+HEYHAE
Sbjct: 25 LEHMCLLDIDSAPTTARNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAE 84
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N REA +S+ + IALDTKGPEIRTGL+ G G+AEVELKKG IK+T
Sbjct: 85 TIKNVREACESFEPGSIQYRPIGIALDTKGPEIRTGLIHGSGTAEVELKKGNVIKITLDD 144
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVS-------ADTLTCTIEN 751
Y EK + + +++DYKNIT VV G++I+IDDGLIS+ + + +D L C IEN
Sbjct: 145 AYVEKCSEEILWLDYKNITKVVDVGSKIYIDDGLISLQVKEIGNSSISSGSDYLMCEIEN 204
Query: 752 GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILG 931
GG LGS+KGVNLPG VDLPAVS+KD DL FGVEQGVDM+FASFIR A +H +R +LG
Sbjct: 205 GGTLGSKKGVNLPGAAVDLPAVSDKDVKDLQFGVEQGVDMVFASFIRKAADVHAVRAVLG 264
Query: 932 EKGKNIR 952
EKGK+I+
Sbjct: 265 EKGKDIK 271
Score = 35.9 bits (79), Expect = 2.1
Identities = 18/31 (58%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Frame = +1
Query: 1012 SDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 326 SDGIMVARGDLGIEIPTEKVFLAQKMMIGRC 356
>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
Homo sapiens (Human)
Length = 574
Score = 272 bits (668), Expect = 9e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 306
Query: 944 NIR 952
I+
Sbjct: 307 GIK 309
Score = 53.6 bits (123), Expect = 1e-05
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 304 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 360
>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 744
Score = 249 bits (609), Expect = 1e-64
Identities = 117/199 (58%), Positives = 145/199 (72%), Gaps = 1/199 (0%)
Frame = +2
Query: 359 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGG 538
M V RMNFSHGSHEYH +TI+ R+A Y + G P +LAIALDTKGPEIRTG L GG
Sbjct: 1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGN 60
Query: 539 S-AEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 715
AE+ELK G+ + L+T + +K N D IYVDY+ + +VKPGNR+F+DDGLI++I +
Sbjct: 61 DRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKE 120
Query: 716 VSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 895
D + C +ENGG LGS KG+NLPG+PVDLP+V+EKDK DL FG EQ VDMIFASFIR+
Sbjct: 121 SKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRD 180
Query: 896 GAXLHEIRGILGEKGKNIR 952
L EIR +LG G I+
Sbjct: 181 ANALKEIRQVLGPAGACIK 199
Score = 64.9 bits (151), Expect = 4e-09
Identities = 32/52 (61%), Positives = 40/52 (76%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
+IISK ENHQG+VN + II ESDGIMVARG +GI IP + P K+++AKC
Sbjct: 199 KIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKC 250
>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
Pyruvate kinase - Leishmania mexicana
Length = 499
Score = 236 bits (577), Expect = 1e-60
Identities = 122/242 (50%), Positives = 163/242 (67%), Gaps = 1/242 (0%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYH 406
SQL H L I + R + ICT GP++++V L ++ GM+VARMNFSHGSHEYH
Sbjct: 2 SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 61
Query: 407 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 586
TI N R+A +A+LG ++AIALDTKGPEIRTG GG + +++G T +TT
Sbjct: 62 QTTINNVRQA----AAELG--VNIAIALDTKGPEIRTGQFVGGDAV---MERGATCYVTT 112
Query: 587 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGML 763
+ +KG D Y+DY+N++ VV+PGN I+IDDG++ + QS + TL CT+ N +
Sbjct: 113 DPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTI 172
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
R+GVNLPG VDLPAVS KD+ DL FGVEQGVDMIFASFIR+ + ++R LG KG+
Sbjct: 173 SDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGR 232
Query: 944 NI 949
+I
Sbjct: 233 DI 234
Score = 60.1 bits (139), Expect = 1e-07
Identities = 31/57 (54%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG + II K ENHQG+ N + II ESDGIMVARG LG+ IP ++ K +I+KC
Sbjct: 230 KGRDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKC 286
>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 554
Score = 213 bits (519), Expect = 1e-53
Identities = 104/242 (42%), Positives = 154/242 (63%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYH 406
+QL H C LD+ ++S+ RL I T +SRN + + G+N+ R+NFSH SHE H
Sbjct: 14 TQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMH 73
Query: 407 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 586
++TI EA + + G ++AIA DT+GP+IRTGLL+G +V L+ G+ ++L+
Sbjct: 74 SKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRSGDNLRLSI 129
Query: 587 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLG 766
+ D +KGN + +YVDY NI N+ K G+R+FIDDG + + V D L C + +GG L
Sbjct: 130 NRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCEVIHGGQLN 189
Query: 767 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
+ V LP I +DLPAVSEKD D+ F ++ VD +FAS +R+ + E+R +LGEKGK+
Sbjct: 190 NNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKH 249
Query: 947 IR 952
I+
Sbjct: 250 IK 251
>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
Pyruvate kinase - Neurospora crassa
Length = 527
Score = 212 bits (517), Expect = 2e-53
Identities = 106/225 (47%), Positives = 145/225 (64%), Gaps = 1/225 (0%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + ICT GP + +V + + G+NV RMNFSHGS+EYH I N R+AEK +
Sbjct: 32 RRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGSYEYHQSVIDNARQAEKVHP--- 88
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G P +AIALDTKGPEIRTG + ++ + G + +TT Y+++ + +YVDY
Sbjct: 89 GRP--IAIALDTKGPEIRTGNTKN--DEDIPISAGTILNITTDEKYKDECTIEHMYVDYV 144
Query: 641 NITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
NIT V+ PG I++DDG+++ + + V T+ N G + SRKGVNLP VDLPA+
Sbjct: 145 NITKVIAPGRIIYVDDGVLAFEVLEIVDDKTIKVKARNNGYISSRKGVNLPNTDVDLPAL 204
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
SEKDK+DL FGV+ VDM+FASFIR G + +IR +LGE GK I+
Sbjct: 205 SEKDKADLRFGVKNKVDMVFASFIRRGQDIKDIREVLGEDGKQIQ 249
Score = 54.8 bits (126), Expect = 4e-06
Identities = 28/56 (50%), Positives = 37/56 (66%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
G++ QII+K EN QG+ N I+ E+DG+MVARG LGI IP + K +IA C
Sbjct: 245 GKQIQIIAKIENRQGLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMC 300
>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
Glycine max (Soybean)
Length = 511
Score = 192 bits (468), Expect = 2e-47
Identities = 101/222 (45%), Positives = 138/222 (62%), Gaps = 3/222 (1%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPASR+V + + GMNVAR NFSHG+H+YH ET+ N + +A +
Sbjct: 26 VCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLK------TAMHNTGIL 79
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
A+ LDTKGPEIRTG L+ G ++LK+G+ + +TT DY KG+ + I + YK +
Sbjct: 80 CAVMLDTKGPEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPVH 135
Query: 656 VKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 829
+KPGN I DG I++ S D T+ C EN LG RK VNLPG+ VDLP ++EKD
Sbjct: 136 LKPGNTILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVNLPGVVVDLPTLTEKD 195
Query: 830 KSDLL-FGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
K D+L +GV +DMI SF+R G+ L +R +LG KNI+
Sbjct: 196 KEDILGWGVPNKIDMIALSFVRKGSDLVNVRKVLGPHAKNIQ 237
Score = 49.6 bits (113), Expect = 2e-04
Identities = 24/52 (46%), Positives = 36/52 (69%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
Q++SK EN +G++N + I+ E+D MVARG LG+ IP ++ + K MI KC
Sbjct: 237 QLMSKVENQEGVLNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKC 288
>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 510
Score = 189 bits (460), Expect = 1e-46
Identities = 102/221 (46%), Positives = 139/221 (62%), Gaps = 3/221 (1%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
ICT GP SR+V ++ ++ GMNVAR NFSHGSH YH ET+ N R A + +
Sbjct: 21 ICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGIL 74
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
A+ LDTKGPEIRTG L+ G ++L +G+ ++T S DY +G+++ I + YK +
Sbjct: 75 SAVMLDTKGPEIRTGFLKEG--KPIQLNQGQ--EITISIDYMIEGDSNVISMSYKKLAED 130
Query: 656 VKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 829
VKPG+ I DG IS+ S S + C EN +LG RK VNLPGI VDLP ++EKD
Sbjct: 131 VKPGDVILCSDGTISLTVLSCDKSFGLVRCRCENSAILGERKNVNLPGIVVDLPTLTEKD 190
Query: 830 KSDLL-FGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
K D++ +GV +D+I SF+R G+ L E+R +LGE KNI
Sbjct: 191 KEDIIQWGVPNKIDIIALSFVRKGSDLTEVRRLLGEHSKNI 231
>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
organisms|Rep: Pyruvate kinase - Eimeria tenella
Length = 531
Score = 185 bits (450), Expect = 2e-45
Identities = 94/224 (41%), Positives = 136/224 (60%), Gaps = 1/224 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GP+ +V + ++ GMNV R+NFSHG HE H ++N +EA K K
Sbjct: 61 VCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK-----R 115
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+A+ LDTKGPEIRTG+LEG +EL G+ +K+ T DY GN I Y+ + +
Sbjct: 116 VALLLDTKGPEIRTGMLEG--DKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPSS 171
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
VKPGN I I DG +S+ D + + N ++G++K +NLPG+ VDLP + EKDK+
Sbjct: 172 VKPGNTILIADGSLSVEVVECGKDYVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGEKDKN 231
Query: 836 DLL-FGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIRSSPR 964
D+L FG+ G + I ASF+++ + IR ILG KG+NI+ P+
Sbjct: 232 DILNFGIPMGCNFIAASFVQSADDVRYIRSILGTKGRNIKIIPK 275
Score = 55.2 bits (127), Expect = 3e-06
Identities = 27/57 (47%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG +II K EN +G++N + I+ E+DGIM+ARG LG+ IP ++ + K MI+KC
Sbjct: 266 KGRNIKIIPKIENVEGLLNFDEILQEADGIMIARGDLGMEIPPEKVFLAQKMMISKC 322
>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
Pyruvate kinase I - Salmonella typhimurium
Length = 470
Score = 179 bits (436), Expect = 1e-43
Identities = 97/220 (44%), Positives = 133/220 (60%), Gaps = 1/220 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GP + + +L ++ GMNV R+NFSHG + H + I+N R +K G
Sbjct: 7 VCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNV----MSKTGK--K 60
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
AI LDTKGPEIRT LEGG +V LK G+T TT D GN + + V Y+ T+
Sbjct: 61 AAILLDTKGPEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTSD 116
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ GN + +DDGLI + ++ + + C + N G LG KGVNLPG+ + LPA++EKDK
Sbjct: 117 LSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQ 176
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGIL-GEKGKNIR 952
DL+FG EQGVD + ASFIR + + EIR L G+NI+
Sbjct: 177 DLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQ 216
Score = 55.2 bits (127), Expect = 3e-06
Identities = 30/56 (53%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
GE QIISK EN +G+ N + I+ SDGIMVARG LG+ IP + K MI KC
Sbjct: 212 GENIQIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKC 267
>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
aerofaciens ATCC 25986|Rep: Pyruvate kinase -
Collinsella aerofaciens ATCC 25986
Length = 486
Score = 177 bits (432), Expect = 4e-43
Identities = 93/218 (42%), Positives = 137/218 (62%), Gaps = 3/218 (1%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPA + + ++ GMNVAR NFSHGS++ H I R K +LG P
Sbjct: 8 VCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP-- 61
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT---TSSDYQEKGNADTIYVDYKNI 646
+ I LDTKGPE+RTGLL G +V +K G+ I +T TS D+ G A+ I +DY +
Sbjct: 62 VGILLDTKGPEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFH--GTAEHISLDYLAL 117
Query: 647 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 826
+ V+ G+ I IDDGL+++ +SV +TC ++N G++G RKGVN+P + + LPA++E+
Sbjct: 118 PSEVEKGSLILIDDGLVALEVESVDGQDMTCVVKNDGLIGERKGVNMPNVNISLPAITER 177
Query: 827 DKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
D+ D+LFG+ + +D I ASFIR+G + IR + E G
Sbjct: 178 DRQDILFGLTENIDYIAASFIRDGESVRGIRELCRENG 215
Score = 44.8 bits (101), Expect = 0.005
Identities = 27/56 (48%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
GE I K E G+ N + I+ SDGIMVARG LGI I + P K +IAKC
Sbjct: 216 GEHVTIFPKIECALGVENFDEILEASDGIMVARGDLGIEIKPELVPHIQKEIIAKC 271
>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
Pyruvate kinase - Bacillus subtilis
Length = 585
Score = 177 bits (430), Expect = 6e-43
Identities = 102/232 (43%), Positives = 143/232 (61%), Gaps = 3/232 (1%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPAS ++ +L ME GMNVAR+NFSHG E H I+N REA K K
Sbjct: 1 MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
LG ++ I LDTKGPEIRT +E GG +EL+ G+ +L S D + G D I V Y
Sbjct: 57 LGK--NVGILLDTKGPEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTY 108
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADT--LTCTIENGGMLGSRKGVNLPGIPVDLP 811
+ + + V+ G+ I +DDGLI + V A + + N G L ++KGVN+PG+ V+LP
Sbjct: 109 EGLVHDVEQGSTILLDDGLIGLEVLDVDAAKREIKTKVLNNGTLKNKKGVNVPGVSVNLP 168
Query: 812 AVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE-KGKNIRSSPR 964
++EKD D++FG+EQGVD I SFIR + EIR +L E ++I+ P+
Sbjct: 169 GITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELLEEHNAQDIQIIPK 220
Score = 53.6 bits (123), Expect = 1e-05
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = +1
Query: 940 EEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKCXGL 1110
++ QII K EN +G+ N + I+ SDG+MVARG LG+ IP + P K +I KC L
Sbjct: 213 QDIQIIPKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNAL 270
>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
organisms|Rep: Pyruvate kinase - Vibrio cholerae
Length = 470
Score = 176 bits (429), Expect = 8e-43
Identities = 98/220 (44%), Positives = 130/220 (59%), Gaps = 1/220 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GP + +V L + GMNV R+NFSHG + H I N R+ + +L
Sbjct: 7 VCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQL----- 61
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
AI LDTKGPEIRT LE G +V+L G+ TT D + GN + + V Y
Sbjct: 62 -AILLDTKGPEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAKD 116
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ GNRI +DDGLI + + + + C + N G LG KGVNLPG+ V+LPA+SEKDK+
Sbjct: 117 LNVGNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSEKDKN 176
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK-GKNIR 952
DL FG EQGVD + ASFIR G+ + EIR +L G+NI+
Sbjct: 177 DLKFGCEQGVDFVAASFIRKGSDVKEIREVLASHGGQNIQ 216
Score = 53.2 bits (122), Expect = 1e-05
Identities = 29/56 (51%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G+ QIISK EN +G+ N + I+ SDGIMVARG LG+ IP + K MI KC
Sbjct: 212 GQNIQIISKIENQEGLDNFDEILELSDGIMVARGDLGVEIPAEEVIFAQKMMIEKC 267
>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 486
Score = 175 bits (425), Expect = 2e-42
Identities = 90/224 (40%), Positives = 142/224 (63%)
Frame = +2
Query: 263 SKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEK 442
S+SS R + ICT GPA+ + ++ E GMNVAR+N SHG+H++H IRN + K
Sbjct: 3 SESSVFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNK 62
Query: 443 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 622
L +P +AI LDT+GPEIRTG L+ ++LK GET E+ +
Sbjct: 63 DV---LKNP--IAILLDTQGPEIRTGDLQVD---HLDLKVGETFTFHIIPG--EESEEQS 112
Query: 623 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 802
++V+YK+I +K G+ + +D+GLI+++ + ++ L C + +GG LGSRK +NLPGI V
Sbjct: 113 VFVNYKDIVKDLKVGDPVTVDNGLINLVVEEINDSALKCKVLDGGRLGSRKHINLPGIRV 172
Query: 803 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE 934
+LP+++ KD D+LFG+E+ VD I SF+R+ +++++ I+ E
Sbjct: 173 NLPSITPKDHKDILFGLEEDVDFIALSFVRSVEDINQLKQIIEE 216
Score = 44.8 bits (101), Expect = 0.005
Identities = 20/50 (40%), Positives = 31/50 (62%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
QII+K E+ + + N I+ +DG+MVARG LG+ +P + P + I K
Sbjct: 222 QIIAKIEDQEAVRNMKEIVEAADGVMVARGDLGVEVPIEELPILQRAIIK 271
>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 506
Score = 173 bits (421), Expect = 8e-42
Identities = 93/243 (38%), Positives = 136/243 (55%), Gaps = 1/243 (0%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYH 406
S+LQ L I + +R + I T GP + + + + G+N+ R+NFSHGS+E+H
Sbjct: 4 SRLQRLANLKIGTPQQ-LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFH 62
Query: 407 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 586
I N ++E+ + G P LAIALDTKGPEIRTG ++ + + TT
Sbjct: 63 QSVIENAVKSEQQFP---GRP--LAIALDTKGPEIRTGRTLN--DQDLYIPVDHQMIFTT 115
Query: 587 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 763
+ + N +Y+DY N+T V+ PG I++DDG++S + Q + L N G +
Sbjct: 116 DASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYI 175
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
S KGVNLP VDLP +S KD DL FGV G+ ++FASFIR + IR LG +G+
Sbjct: 176 ASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGSEGQ 235
Query: 944 NIR 952
+I+
Sbjct: 236 DIK 238
Score = 50.8 bits (116), Expect = 7e-05
Identities = 26/57 (45%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXI-PXKRYPXPKNMIAKC 1101
+G++ +IISK EN QG+ N + I+ +DG+M+ARG LGI I + K +IAKC
Sbjct: 233 EGQDIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKC 289
>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
Pyruvate kinase - Clostridium phytofermentans ISDg
Length = 580
Score = 168 bits (409), Expect = 2e-40
Identities = 92/223 (41%), Positives = 131/223 (58%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPA+ + AVL M GM+VAR NFSHG +E H R SA+
Sbjct: 1 MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRRL----SAE 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
L P +A LDTKGPEIR G E G ++ELKKG+ LTT+ G+ + + Y
Sbjct: 57 LKLP--IATLLDTKGPEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITY 108
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
KN+ +K G +I IDDGLI + +++ + C + NGGM+ + KGVN+PG+ + +P +
Sbjct: 109 KNLIRDIKNGVKILIDDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPGVELSMPFI 168
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
S++D D++FG+ QG D I ASF R + +IR IL E N
Sbjct: 169 SKRDYEDIVFGIGQGFDFIAASFTRCADDIIQIRKILNEYNCN 211
Score = 51.2 bits (117), Expect = 5e-05
Identities = 26/49 (53%), Positives = 33/49 (67%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
II+K EN QG+ N + II SDGIMVARG +G+ IP + P + MI K
Sbjct: 215 IIAKIENLQGVNNIDEIIRVSDGIMVARGDMGVEIPLEEVPVIQKMIIK 263
>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
Pyruvate kinase - Phaeodactylum tricornutum
Length = 543
Score = 168 bits (409), Expect = 2e-40
Identities = 92/223 (41%), Positives = 131/223 (58%), Gaps = 3/223 (1%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GPA NV L +E GMNVAR NFSHG H H + R+A ++
Sbjct: 31 RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
++AI LDTKGPEIRTG G S ++EL KGETI LT SDY+ KG+ + Y
Sbjct: 89 ----NIAILLDTKGPEIRTGFFANGAS-KIELVKGETIVLT--SDYKFKGDQHKLACSYP 141
Query: 641 NITNVVKPGNRIFIDDG--LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 814
+ V G +I + DG +++++ +A ++C I+N +G RK +NLPG+ VDLP
Sbjct: 142 ALAQSVTQGQQILVADGSLVLTVLQTDEAAGEVSCRIDNNASMGERKNMNLPGVKVDLPT 201
Query: 815 VSEKDKSDLL-FGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
+EKD D++ FG++ VD I ASF+R + + +R +L E G
Sbjct: 202 FTEKDVDDIVNFGIKHKVDFIAASFVRKQSDVANLRQLLAENG 244
Score = 42.3 bits (95), Expect = 0.024
Identities = 20/54 (37%), Positives = 33/54 (61%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G++ +I K EN +G+ N + I+ +D IMVARG LG+ IP + + M+ +
Sbjct: 245 GQQIKICCKIENQEGLENYDAILQATDSIMVARGDLGMEIPPAKVFLAQKMMIR 298
>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
Oligohymenophorea|Rep: Pyruvate kinase family protein -
Tetrahymena thermophila SB210
Length = 505
Score = 167 bits (405), Expect = 7e-40
Identities = 86/225 (38%), Positives = 132/225 (58%), Gaps = 1/225 (0%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GP+ + L +E GMNVAR+NFSHG H H ET+R +EA K+
Sbjct: 22 RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKARKN-- 79
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
A+ LDTKGPEIRTGL++ + L G+ +++TT DY G+ + YK
Sbjct: 80 ---IQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYK 134
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
++ VK G ++ I DG + I + + D++ ++N +G +K +NLPG VDLP V+
Sbjct: 135 SLPKSVKVGGQVLIADGTLVCIVKEIKQDSIIVNVQNTCSIGEKKNMNLPGAIVDLPTVT 194
Query: 821 EKDKSDLL-FGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
EKD+ D++ FG++ G+D I SF R + +R ILG +G++I+
Sbjct: 195 EKDEDDIVNFGLKHGIDCIALSFARKAEDIEYVRDILGPQGEHIK 239
Score = 48.8 bits (111), Expect = 3e-04
Identities = 26/56 (46%), Positives = 37/56 (66%), Gaps = 1/56 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAK 1098
+GE +II+K EN +G+ N I+ +DGIMVARG LG+ IP ++ + K MI K
Sbjct: 234 QGEHIKIIAKIENQEGLHNYEQILDAADGIMVARGDLGMEIPPQKVFVAQKWMIRK 289
>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
Length = 483
Score = 165 bits (400), Expect = 3e-39
Identities = 86/215 (40%), Positives = 129/215 (60%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GPAS +V V+ ++ GMNVAR+NFSHGS+E HA +R R E+ ++ +P +
Sbjct: 21 VATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPIT 76
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
L D +GP+IR G L GG E +L++GE + L A + +DY ++
Sbjct: 77 LL--QDLQGPKIRIGQLPGG---EKQLREGEKVSLVPVEIGDRHPGA--VGIDYPHLATE 129
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
K G RI +DDGL+ + S+ + C + GG+L SRKGVNLPG+ + LP+++ KDK
Sbjct: 130 AKVGERILLDDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNLPGLVLTLPSMTTKDKQ 189
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
DL FG+ QG+D + SF+R G +H ++ L E+G
Sbjct: 190 DLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAERG 224
Score = 39.9 bits (89), Expect = 0.13
Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
+I+K E Q + N I+ S+GIMVARG LG+ + ++ P K +I +C
Sbjct: 230 VIAKIEKPQAIDNLEEIVAVSNGIMVARGDLGVEVNPEKVPRLQKEIIRRC 280
>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
annulata
Length = 513
Score = 163 bits (396), Expect = 8e-39
Identities = 88/224 (39%), Positives = 129/224 (57%), Gaps = 1/224 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPA NV + ++ GMN+ R NFSHG+HE H +T+ +EA KS +
Sbjct: 43 VCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA-----N 97
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ + LDTKGPEIRTG L+ + L++G T+K+TT DY +G+ I YK +
Sbjct: 98 IGLMLDTKGPEIRTGFLKN--HTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQS 153
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
VK GN I I DG +S +V D + + N +G K +NLPG+ V+LP ++E DK
Sbjct: 154 VKVGNIILIADGSLSCEVLAVFDDYIEVKVLNNAKIGEYKNMNLPGVKVELPVLTESDKD 213
Query: 836 DLL-FGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIRSSPR 964
+L FG+ +D I SF + + +R +LGEKGK+I+ P+
Sbjct: 214 YILNFGIPNQMDFIALSFTQTAEEVKYVRELLGEKGKHIKIIPK 257
Score = 49.6 bits (113), Expect = 2e-04
Identities = 24/55 (43%), Positives = 36/55 (65%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
KG+ +II K EN +G+ N + I+ SDGIMVARG LG+ +P ++ + M+ K
Sbjct: 248 KGKHIKIIPKIENIEGLANYDEILEASDGIMVARGDLGMEMPIEKVCLAQKMMIK 302
>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
(Water mold)
Length = 517
Score = 161 bits (391), Expect = 3e-38
Identities = 83/222 (37%), Positives = 130/222 (58%), Gaps = 3/222 (1%)
Frame = +2
Query: 263 SKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEK 442
SK+ ++ + T GP S N G+ + R+NFSH +++ + + R ++
Sbjct: 23 SKNDAFSMTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKG 82
Query: 443 SYSAKLGSPFSL-AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 619
++ G F++ A+ LDT+GPEIR G ++ L KG+ I LTT Y+E D
Sbjct: 83 VHAKHTGKEFNVRAVLLDTQGPEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKD 139
Query: 620 TIYVDYKNITNVVKPGNRIFIDDGLISIICQS--VSADTLTCTIENGGMLGSRKGVNLPG 793
+YV Y+ + VK G+ + +DDGLIS+ +S V++ + C IEN +LGSRKGVNLPG
Sbjct: 140 MLYVTYEQLPATVKVGDTVLLDDGLISLTVKSIDVASGQVRCLIENSEVLGSRKGVNLPG 199
Query: 794 IPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIR 919
+ VDLPA++ KDK D+ FGVE +D I SF+R +++++
Sbjct: 200 LVVDLPALTAKDKQDVEFGVEHDMDFIAVSFVRKPEDVNDVK 241
Score = 52.8 bits (121), Expect = 2e-05
Identities = 26/51 (50%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
IISK EN++G+ N + I+ SDGIMVARG LG+ IP + K+M++KC
Sbjct: 261 IISKIENYEGVSNFDRILEVSDGIMVARGDLGVEIPMQEVLTCQKDMVSKC 311
>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 515
Score = 158 bits (383), Expect = 3e-37
Identities = 88/225 (39%), Positives = 131/225 (58%), Gaps = 1/225 (0%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPAS++ +L +E GM+VAR+NFSHGSHE HAE I R A S K
Sbjct: 10 MRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SLK 65
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
L ++ I D +GP+IRTG G + LK+G +TT D KGN D + Y
Sbjct: 66 LRK--AVGILGDLQGPKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTY 118
Query: 638 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 814
++ V PG+RI +DDGL+ + + ++ L + GG L + KG+NLPG+ V A
Sbjct: 119 AHLAADVNPGDRILLDDGLLELKVLETDKKQLLRTQVVIGGTLKNNKGINLPGVAVRADA 178
Query: 815 VSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
++ KD+ DL+FG+++GVD + SF+R A + R + E G+ +
Sbjct: 179 LTPKDREDLVFGIKEGVDFLALSFVRQPADIELARQAMAEAGRQV 223
Score = 39.1 bits (87), Expect = 0.23
Identities = 16/43 (37%), Positives = 28/43 (65%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXK 1065
G + I++K E + + + I+ ++DG+MVARG LG+ IP +
Sbjct: 220 GRQVPIVAKLEKPEAIARLDAILDKTDGVMVARGDLGVEIPPR 262
>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
(class)|Rep: Pyruvate kinase - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 475
Score = 156 bits (379), Expect = 9e-37
Identities = 80/223 (35%), Positives = 125/223 (56%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GPA + + +E GM+VAR+NFSHG H H + + REA + +
Sbjct: 3 RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G I D +GP+IR G G + + GETI++T +G D + YK
Sbjct: 63 G------ILADLQGPKIRLGRFTDGATV---WENGETIRITVDD---VEGTHDRVSTTYK 110
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
N+ KPG+R+ +DDG + ++C SV + + C + GG + + KGV+LPG+ + +PA+S
Sbjct: 111 NLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLPGMDISVPALS 170
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
EKD DL F ++ GVD I SF+R+ A + I+ E+G+ +
Sbjct: 171 EKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEGRRV 213
Score = 36.3 bits (80), Expect = 1.6
Identities = 15/47 (31%), Positives = 26/47 (55%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
+G +I+K E + + + I+ D +MVARG LG+ +P + P
Sbjct: 209 EGRRVPVIAKLEKPEAVTSLEPIVLAFDAVMVARGDLGVEVPLEEVP 255
>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
sulfurreducens
Length = 480
Score = 156 bits (378), Expect = 1e-36
Identities = 89/219 (40%), Positives = 129/219 (58%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + I T GP S + ++ M+ G++V R+NFSHGS++ E I R SA+
Sbjct: 6 RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVIAAIRRL----SAER 61
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G + I D +GP+IRTG +E G + L +G+++ +TT G TIY +
Sbjct: 62 GK--EIGILADLQGPKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTIY---Q 113
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
++ + VKPG+RI +DDGLI + QSVS T+ CT+ GGML KG+NLPG+ V P++S
Sbjct: 114 SLPHDVKPGSRILLDDGLIELRVQSVSGATVRCTVVQGGMLKDLKGINLPGVKVSAPSLS 173
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
EKD DL F +E GVD I SF+R A + ++ IL E+
Sbjct: 174 EKDLRDLDFCLEVGVDYIALSFVRTAADVEGLKRILFER 212
Score = 35.9 bits (79), Expect = 2.1
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
+++K E + + N I+ +D +MVARG LG+ I ++ P K +I C
Sbjct: 218 VVAKIEKPEALRNFKSILKVADAVMVARGDLGVEISPEKVPLFQKKIIRAC 268
>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Pyruvate kinase -
Desulfuromonas acetoxidans DSM 684
Length = 474
Score = 153 bits (370), Expect = 1e-35
Identities = 85/219 (38%), Positives = 128/219 (58%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPAS + A L + GMNVAR+NFSHG H+ H + I R K +
Sbjct: 1 MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
L P +AI D GP+IR G L G V L +G+ + L ++ + G D + VDY
Sbjct: 57 LNQP--VAILQDLCGPKIRLGQLPEQG---VRLHQGDAVSLCSTG---QAGEGD-LPVDY 107
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
++ V+ G+ I + DGL+ + + + A + C++ +GG+ SRKGVN+P + +PA
Sbjct: 108 PSLHEDVQVGDSIMLSDGLMELQVERIDAPQVQCSVISGGVAYSRKGVNMPSSHLSIPAF 167
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE 934
+EKD+ DL FG++QGVD++ SF+R L EIR +L E
Sbjct: 168 TEKDRDDLRFGLQQGVDIVALSFVRGADDLKEIRTMLAE 206
Score = 35.1 bits (77), Expect = 3.7
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Frame = +1
Query: 940 EEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAK 1098
E ++++K E Q + + I+ D +M+ARG LG+ +P ++ P K +I K
Sbjct: 209 EAPKLVAKIEKPQAVAHIEEILDVVDVVMIARGDLGVEVPLEQVPVLQKQLIHK 262
>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
PR1
Length = 476
Score = 152 bits (369), Expect = 2e-35
Identities = 83/219 (37%), Positives = 122/219 (55%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GPAS N + G NV R+NFSHGSH+ H E I R+ K + LG
Sbjct: 12 LATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG---- 67
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
I D +GP+IR G +E G VE+K GE K+T ++D G + + Y+N+
Sbjct: 68 --ILQDLQGPKIRVGEVENNG---VEIKPGE--KITITND-PVVGTSTLVSTVYQNLPQD 119
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V G+RI IDDG + ++ + CT+ +GG+L SRKG+NLP V P+++EKD
Sbjct: 120 VVSGDRILIDDGNLEVVVNDTDGKNVNCTVIHGGILKSRKGINLPNTKVSAPSLTEKDIE 179
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
DL FG+ + VD I SF+R+ + ++R + KGK+ +
Sbjct: 180 DLAFGLSKEVDWIALSFVRSAEDIEDLRERIEAKGKHCK 218
Score = 45.6 bits (103), Expect = 0.003
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
KG+ +I++K E + + N + II +D IMVARG LG+ +P + P K ++ KC
Sbjct: 213 KGKHCKIVAKIEKPEALENIDGIIEATDAIMVARGDLGVEVPMEIVPLWQKRIVEKC 269
>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
group|Rep: Pyruvate kinase - Bacillus anthracis
Length = 352
Score = 148 bits (359), Expect = 2e-34
Identities = 80/211 (37%), Positives = 120/211 (56%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPAS N L + GM + R+N SHG+HE H + IR + + S
Sbjct: 6 VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS---------- 55
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ I D +GP+IR G ++G ++ L+ G++ L T G++ VDY+ I N
Sbjct: 56 IKILGDVQGPKIRLGEIKG---EQITLQAGDSFMLRTQP---VTGSSTEASVDYEGIAND 109
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
VK G+RI ++DG + +I + VS D + ++ GG + S KGVNLPG V LPA++EKDK
Sbjct: 110 VKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVSLPAITEKDKK 169
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
D+ F +E+ VD I SF+R + + EIR +
Sbjct: 170 DIQFLLEEDVDFIACSFVRKPSHIKEIRDFI 200
Score = 41.9 bits (94), Expect = 0.032
Identities = 21/51 (41%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
+I+K E + + N I E+DGIM+ARG LG+ +P + P K MI +C
Sbjct: 210 LIAKIETMEAIENFQDICKEADGIMIARGDLGVELPYQFIPLLQKMMIQEC 260
>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 481
Score = 147 bits (357), Expect = 4e-34
Identities = 82/214 (38%), Positives = 121/214 (56%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + ICT GPAS V+ + GMNVAR+NFSHG +E H + R+ S K
Sbjct: 16 MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
LG P +AI D +GP+IR G EGG ++ ++ G+T+ +TT + G I
Sbjct: 72 LGIP--VAILQDIQGPKIRLGRFEGG---QLLVQAGQTVTVTTRAVL---GQGTLIPTPV 123
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+++T V G+ I +DDG + + V+ +T T+E GG+L KG+NLPG + +P +
Sbjct: 124 RSLTRDVTRGDMILLDDGRVRLRVVRVAGRDVTATVEVGGLLKDHKGLNLPGAAISVPTI 183
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIR 919
+EKD DL FG E GVD + SF+R +H+ R
Sbjct: 184 TEKDAEDLAFGQELGVDYVALSFVRTANDIHQAR 217
Score = 40.7 bits (91), Expect = 0.074
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAK 1098
+I+K E Q + N I +DG+MVARG LG+ +P ++ P K M+A+
Sbjct: 227 LIAKIEKPQALENLEAISEAADGVMVARGDLGVEMPLEQLPGIQKRMVAE 276
>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
mazei (Methanosarcina frisia)
Length = 477
Score = 147 bits (357), Expect = 4e-34
Identities = 83/218 (38%), Positives = 119/218 (54%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPAS + ++ M GMNVAR+NFSHG E H+ +R R+ + +LG +
Sbjct: 11 VCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR--T 64
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+AI D GP+IR G LE V L KG I LT GN + I V YK +
Sbjct: 65 IAILADLPGPKIRIGKLE---KEPVMLHKGNPITLTIDDT---PGNEERIPVSYKQLPES 118
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V PG+ I++ DG I ++C+ V+ + C + GG L S KG+NLPG + L AV+EKD
Sbjct: 119 VTPGSLIYLSDGFIQLLCKEVTGKDVLCEVLIGGELYSHKGLNLPGAKIFLDAVTEKDFR 178
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
L F +E+ +D SF+ N + ++R +GK +
Sbjct: 179 ILEFALEEDIDTFSISFVENAEDIRKVRNFAASRGKQV 216
Score = 46.0 bits (104), Expect = 0.002
Identities = 20/47 (42%), Positives = 30/47 (63%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
+G++ I+SK E Q + N I+ E+D +MVARG LG+ IP + P
Sbjct: 212 RGKQVNIVSKIERRQAVENIGEILDETDALMVARGDLGVEIPIQEVP 258
>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
Length = 491
Score = 146 bits (355), Expect = 8e-34
Identities = 80/222 (36%), Positives = 124/222 (55%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GPAS + VL + G++VAR+NFSHG HE HA+ + R A S
Sbjct: 4 MRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA----SRH 59
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
LG ++A+ D +GP+IRTG L G V L+ G + + T D + KG+A + Y
Sbjct: 60 LGR--AVAVLQDLQGPKIRTGPLAAGREG-VRLEAGAELVIAT--DAEVKGDAKLVSTTY 114
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
++ V+PG+R+ +DDGLI + C + GG+L KG+NLPG+ + A+
Sbjct: 115 PHLAEDVRPGDRLLVDDGLIELRVLETDGVRARCQVVEGGVLREHKGINLPGVALRAEAL 174
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
SEKD++D+ FG+ GVD + SF+R+ + R + G+
Sbjct: 175 SEKDRADIAFGLAHGVDAVALSFVRSAEDIRACRDEMERVGR 216
Score = 35.9 bits (79), Expect = 2.1
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
+I+K E + + + II +DGIM+ARG LG+ I +R P
Sbjct: 220 VIAKIEKPEALDAIDAIIEAADGIMIARGDLGVEILPERVP 260
>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
Pyruvate kinase - Propionibacterium acnes
Length = 477
Score = 146 bits (353), Expect = 1e-33
Identities = 76/227 (33%), Positives = 130/227 (57%), Gaps = 3/227 (1%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GPA + + ME GMN+AR+N SHG + H E + + +S S +
Sbjct: 1 MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLE---GGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 628
LG ++A D +GP+IRTGL E G + +++LK G+ +TT GN + +
Sbjct: 57 LG--LNVAALADLQGPKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVS 111
Query: 629 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 808
+K + KPG+ I IDDG + SVS + + C G +G KG+NLPG+ V +
Sbjct: 112 TTFKGLPQDCKPGDVILIDDGKTVLQVDSVSGNDVNCHCTVAGPVGDHKGINLPGVAVSI 171
Query: 809 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
PA+++KD+ +L + ++ G+D++ SF+R+G+ + + I+ E+G+ +
Sbjct: 172 PALTKKDEENLRWALKAGIDLVALSFVRHGSDIDRVHEIMDEEGRTV 218
Score = 34.3 bits (75), Expect = 6.4
Identities = 17/53 (32%), Positives = 27/53 (50%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMI 1092
+G +I+K E Q + N + II D +MVARG + + P + P + I
Sbjct: 214 EGRTVPVIAKLEKPQAIENLDEIIDVFDAVMVARGDMAVECPLEEVPLIQKQI 266
>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to pyruvate kinase - Candidatus Kuenenia
stuttgartiensis
Length = 472
Score = 145 bits (351), Expect = 2e-33
Identities = 83/223 (37%), Positives = 125/223 (56%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GPAS + A++ + GMNVAR+NFSHG H E I + R + S KL
Sbjct: 5 RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
P +A+ D GP+IR G+L G V LK +T LTT + GN I ++Y
Sbjct: 61 MQP--VAVLQDLSGPKIRIGMLSGDA---VTLKTNDTFTLTTRNIV---GNERVISINYS 112
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
++ V G+ + + DG I + + C + GG+L SRKG+N+P + + +++
Sbjct: 113 DLPMNVSIGDTLLLSDGEIEVEVIQKDDRNIHCKVIVGGVLTSRKGINIPARSLPVSSLT 172
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
EKDK DL FG+EQGVD + SF++ + E+R ++ +KGK I
Sbjct: 173 EKDKKDLEFGIEQGVDYVAMSFVKTAEDITELRDLIQKKGKTI 215
Score = 50.4 bits (115), Expect = 9e-05
Identities = 24/55 (43%), Positives = 34/55 (61%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
KG+ II+K E H+ + N I+ +D IMVARG LG+ IP +R P + MI +
Sbjct: 211 KGKTIPIIAKIEKHEAVDNIEKIVNTADAIMVARGDLGVEIPLERVPSVQKMIIR 265
>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
Pyruvate kinase - Mycobacterium tuberculosis
Length = 472
Score = 144 bits (348), Expect = 5e-33
Identities = 72/218 (33%), Positives = 120/218 (55%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPA++ ++ +E GM+VARMNFSHG ++ H R A + +G
Sbjct: 8 VCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVG---- 63
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ D +GP+IR G G + E GET+++T + +G+ D + YK +
Sbjct: 64 --VLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYKRLAQD 115
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
G+R+ +DDG ++++ +V D + CT+ GG + KG++LPG+ V PA+SEKD
Sbjct: 116 AVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIE 175
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
DL F + GVDM+ SF+R+ A + + ++ G+ +
Sbjct: 176 DLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRV 213
Score = 36.3 bits (80), Expect = 1.6
Identities = 16/46 (34%), Positives = 25/46 (54%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
G +I+K E + + N I+ D +MVARG LG+ +P + P
Sbjct: 210 GRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVP 255
>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
Length = 591
Score = 143 bits (346), Expect = 9e-33
Identities = 83/227 (36%), Positives = 131/227 (57%), Gaps = 4/227 (1%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPA+++ VL ++ G R+NFSHG H YH ++IR R+ + +L
Sbjct: 8 RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQI----AFEL 63
Query: 461 GSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VD 634
P + I D +GP+IR G L GS V+LK G+ LT+ + +TI +
Sbjct: 64 NQP--VGILQDLQGPKIRVGKFLNDAGS--VQLKNGDPYTLTS----RPVECTETISSIS 115
Query: 635 YKNITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDL 808
Y+ + + V G RI +DDG + ++ + V A L C + GG L S KGVN PG+ + +
Sbjct: 116 YEYLADEVPSGARILLDDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNKGVNFPGVCLSV 175
Query: 809 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
A+++KDK DL+FG++QGVD + SF+RN + EI+G++ GK++
Sbjct: 176 KAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAGKSV 222
Score = 41.9 bits (94), Expect = 0.032
Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIA 1095
G+ +I+K E H+ + + ++ + DG+MVARG LG+ +P + P K +IA
Sbjct: 219 GKSVPVIAKIEKHEAIKDMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIA 272
>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
dehalogenans 2CP-C|Rep: Pyruvate kinase -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 489
Score = 142 bits (345), Expect = 1e-32
Identities = 76/205 (37%), Positives = 119/205 (58%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GPAS VL +E G++VAR+NFSHG HE HA + R A S
Sbjct: 1 MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
LG ++A+ D +GP+IRTG L+ G A V+++ G+ + +TT + G+A + Y
Sbjct: 57 LGK--AVAVLQDLQGPKIRTGPLKAG-KAGVQVEAGQELVITTEGELP--GDAHLVSTTY 111
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
++ V+ G+R+ +DDGL+ + + + GG LG KG+NLPG+ + A+
Sbjct: 112 PHLAEDVRAGDRLLVDDGLLEFRVLATDGVRVRTEVVEGGWLGEHKGINLPGVALRAEAL 171
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIR 892
SEKD++D+ FG+ GVD + SF+R
Sbjct: 172 SEKDRADVAFGISHGVDYVALSFVR 196
Score = 39.1 bits (87), Expect = 0.23
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
II+K E + + N + II +DG+MVARG LG+ I +R P
Sbjct: 217 IIAKIEKPEAIDNLDAIIAAADGVMVARGDLGVEILPERVP 257
>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 509
Score = 142 bits (343), Expect = 2e-32
Identities = 76/223 (34%), Positives = 118/223 (52%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GPA A + M GM+VAR+NFSHG+H+ H I+ R+
Sbjct: 20 RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
S+ I D +GP+IRTGLL+ V L+ G T+ +T G+A + ++
Sbjct: 78 ----SICILQDLQGPKIRTGLLKD--HKPVMLETGNTVTITPRDIV---GDASLLATTFQ 128
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
+ V+PG+RI + DG I + + + C I NGG L +G+N+PG + +PA++
Sbjct: 129 TLALDVQPGSRILLSDGKIELSVSRIEGADVECHIVNGGELKEHQGINIPGAILSIPALT 188
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
KD DL FG++ GVD + SF+R L ++R + E N+
Sbjct: 189 NKDLEDLAFGLKNGVDAVAISFVRTANDLKQVRNAISEHQGNV 231
Score = 42.7 bits (96), Expect = 0.018
Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 4/56 (7%)
Frame = +1
Query: 943 EHQ----IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
EHQ +I+K E Q + + I E+DG+MVARG LG+ +P ++ P + I K
Sbjct: 226 EHQGNVFVIAKLEKPQAIEHLEEIFNETDGVMVARGDLGVEVPPEKVPVLQKHIIK 281
>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 610
Score = 142 bits (343), Expect = 2e-32
Identities = 79/224 (35%), Positives = 124/224 (55%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPAS +V + + GM+VAR+N SHGS E+ E I R+ +++
Sbjct: 15 MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEEP 74
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
+ A LD GPE+RT ++ ++L +G TI+ D A V
Sbjct: 75 V------AAMLDMPGPEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGL 118
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
V+PG+R+ +DDG I + V +T+ T+ENGG L +RKGVN+PG+ +DLP +
Sbjct: 119 SQSITAVEPGDRVLLDDGRIETTVERVEDETVFATVENGGELAARKGVNVPGVELDLPTI 178
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
+E D+ +L E+ D + ASF+R+G ++EI L E+G +I
Sbjct: 179 TENDEQELDVAAEKEPDFVAASFVRDGEDIYEISQALEERGVDI 222
Score = 40.3 bits (90), Expect = 0.097
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
+G + II+K E + N + II E+ G+MVARG LG+ P + P K +I +C
Sbjct: 218 RGVDIPIIAKIERAGAVENLDSIIDEAYGVMVARGDLGVECPLEDVPIIQKRIIRRC 274
>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
Length = 519
Score = 141 bits (342), Expect = 3e-32
Identities = 78/218 (35%), Positives = 126/218 (57%)
Frame = +2
Query: 284 LSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 463
L+ +CT GP + + + ++ GM++AR+NFSHGS E H E IRN R++ G
Sbjct: 96 LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRDSRS------G 149
Query: 464 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 643
+ ++IALDT+GPE+R E +++++ GE ++ + S ++ VD K+
Sbjct: 150 AGRHVSIALDTRGPEVRLRTPE---MKDIKVEGGEVLRFSLLSSEKDIWIPG---VDLKS 203
Query: 644 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 823
+ NR+FIDDG I + +V D C + N GM+ S K +N PG + A+ +
Sbjct: 204 LG----VDNRVFIDDGAIELRVVNVEEDGFECEVLNSGMIKSNKSMNFPGTDIGDRALGD 259
Query: 824 KDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
+DK+D+ FG+E G+DM+FASF+ A + EIR ++G K
Sbjct: 260 EDKNDIAFGLENGIDMVFASFVSCRADVEEIRRLVGSK 297
Score = 37.1 bits (82), Expect = 0.91
Identities = 18/40 (45%), Positives = 25/40 (62%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXI 1056
G + ++SK E+ GM N I SDG+M+ARG LG+ I
Sbjct: 295 GSKVPVVSKIESCLGMRNLKEIALCSDGVMIARGDLGVEI 334
>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
Pyruvate kinase - Methanosarcina acetivorans
Length = 489
Score = 141 bits (342), Expect = 3e-32
Identities = 79/218 (36%), Positives = 115/218 (52%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPAS + VL + GMNVAR+NFSHG E H + IR R+ + +
Sbjct: 23 VCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------T 76
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+AI D GP+IR G L+ + L KG I LTT + G+ D I V+YK +
Sbjct: 77 VAILADLPGPKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPES 130
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V PG+ I++ DG I ++C +S + C + GG L S KG+NLPG + L +V+E D
Sbjct: 131 VSPGSLIYLSDGFIQLLCLEISGKDVVCEVMVGGQLYSHKGLNLPGAKIYLDSVTEHDFK 190
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
L F + + VD + SF+ + ++R GK +
Sbjct: 191 ILEFALNEEVDAVSISFVEKAEDIRKVRNFASTMGKPV 228
Score = 42.7 bits (96), Expect = 0.018
Identities = 19/46 (41%), Positives = 28/46 (60%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
G+ ++SK E Q + N I+ E+D +MVARG LG+ IP + P
Sbjct: 225 GKPVYVVSKIERSQAVQNIEEILEETDALMVARGDLGVEIPIQEVP 270
>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
bacteriovorus
Length = 495
Score = 140 bits (338), Expect = 9e-32
Identities = 76/224 (33%), Positives = 122/224 (54%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPA+R+ L ++ GMNVAR+NFSHGSHE H + + + R+ K A +
Sbjct: 5 RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQAPV 64
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
AI D +GP+IR G E G +E+K GE + +TT+ + G + D++
Sbjct: 65 ------AILQDLQGPKIRVGKFENGS---IEIKPGEKLVVTTA---KVLGKPGLVPSDFQ 112
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
+ PG RI +DDGL+ + V + + + GG+L RKG+NLPG+ + + ++
Sbjct: 113 ELPLACVPGTRILLDDGLMEVKVLQVRGEEIDVEVVYGGILKDRKGMNLPGVNLPVDCMT 172
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KD DL FG+ VD I SF+R+ + ++R ++ N +
Sbjct: 173 PKDLEDLQFGIANKVDYIALSFVRHARDIRKLRELIEAGNSNAK 216
>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
Protochlamydia amoebophila (strain UWE25)
Length = 598
Score = 139 bits (337), Expect = 1e-31
Identities = 82/216 (37%), Positives = 121/216 (56%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPA ++ + + GMNVAR+NFSHG+ E H TI +EA +L P
Sbjct: 9 VCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP-- 62
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
LAI LDTKGPEIR G + G ++ L G+ +L + G+ + + NI +
Sbjct: 63 LAIMLDTKGPEIRLGKIRDG---QIFLTVGQKWRLVKK---EVLGDESQVSIFPLNILDQ 116
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ G I DDG I+ S++ + I N GM+ S KGVN+P ++LPAV+EKD
Sbjct: 117 LPVGTTILFDDGYIASRVIENSSEGVLVEINNSGMIRSSKGVNIPNTSLNLPAVTEKDID 176
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
D+ FG Q +D+I ASF+R+ + EI+ +L ++ K
Sbjct: 177 DIRFGCSQDIDLIAASFVRSAEHVLEIKRLLADEKK 212
Score = 46.8 bits (106), Expect = 0.001
Identities = 19/49 (38%), Positives = 32/49 (65%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
+I+K EN +G+ N + I+ +DGIM+ARG LG+ +P P + M+ +
Sbjct: 217 VIAKIENSEGVQNFDSIVQAADGIMIARGDLGVEVPLSHVPRLQKMMIR 265
>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 492
Score = 139 bits (336), Expect = 2e-31
Identities = 82/216 (37%), Positives = 123/216 (56%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPASR+ A+L + GMNVAR+NFSHG+HE H REA + +L P
Sbjct: 29 VCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREAAQ----RLMKP-- 82
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+AI D +G ++R G ++ S + L++G+ I L + E ++ I +DY++I
Sbjct: 83 VAILQDLQGHKVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQDIIQY 136
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V PG ++F+DD I + S+ L C ++ GG L SRKGV P + P ++EKD +
Sbjct: 137 VTPGQKVFLDDASIELEVLSIEEKDLHCQVKFGGQLRSRKGVIFPDSQLSFPLLNEKDAT 196
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
D FGV VDM+ SF+R+ + E+R L E G+
Sbjct: 197 DARFGVFLDVDMVAMSFVRSATEIIEMRLRLAEWGQ 232
Score = 45.2 bits (102), Expect = 0.003
Identities = 18/41 (43%), Positives = 31/41 (75%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
II+K E+H+G+ N + I+ +DG++VARG LG+ +P ++ P
Sbjct: 237 IIAKIEDHKGIDNLDEILQVADGVLVARGDLGVTLPREKVP 277
>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
Pyruvate kinase - Vitis vinifera (Grape)
Length = 621
Score = 138 bits (333), Expect = 4e-31
Identities = 74/223 (33%), Positives = 125/223 (56%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GP++ + ++ E GMNVAR+N SHG H H +TI +E + K+
Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
+AI LDTKGPE+R+G + + LK+G+ T + +T+ V+Y
Sbjct: 226 -----IAIMLDTKGPEVRSGDVP----KPIMLKEGQEFNFTIKRGVSSE---NTVSVNYD 273
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
+ N V+ G+ + +D G++S+ +S S D + C + +GG L SR+ +N+ G LP+++
Sbjct: 274 DFVNDVEVGDILLVDGGMMSLAVKSKSKDLVKCQVIDGGELKSRRHLNVRGKSATLPSIT 333
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
+KD D+ FGV+ VD SF+++ +HE++ L G +I
Sbjct: 334 DKDWEDIKFGVDNQVDFYAVSFVKDAEVVHELKDYLRSCGADI 376
Score = 41.1 bits (92), Expect = 0.056
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKCXGLE 1113
G + +I K E+ + N + II SDG MVARG LG +P + P +++I +C ++
Sbjct: 373 GADIHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCHSMQ 432
>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
Length = 482
Score = 137 bits (332), Expect = 5e-31
Identities = 78/219 (35%), Positives = 119/219 (54%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R S + T GPAS + +L G++ R+NFSHG+ HAE RN R E+ + A
Sbjct: 7 RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
++A+ D +GP+IR G+L G ++L +G TI + E N I + ++
Sbjct: 65 ----AIAVLQDLQGPKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHR 115
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
I V PG + IDDG I + V L C + NGG L +RKGVN+PG +D+ ++
Sbjct: 116 EIFEVAVPGMDLLIDDGRIKVRIMEVMDGRLVCEVLNGGALSNRKGVNVPGAVLDISPLT 175
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
KD+ DL FG+E GVD + SF++ + E R ++G++
Sbjct: 176 AKDREDLEFGLELGVDWVALSFVQRARDMIEARSLVGDR 214
Score = 37.5 bits (83), Expect = 0.69
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G+ +I+K E + + I+ SD +MVARG LG+ IP + P K +I C
Sbjct: 212 GDRAGLIAKIEKPSALDDIEDIVRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRAC 267
>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
(strain DSM 13855)
Length = 476
Score = 137 bits (331), Expect = 6e-31
Identities = 74/221 (33%), Positives = 119/221 (53%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GPA+ + L + GM+VARMNFSHG+HE H E + RE ++
Sbjct: 3 RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
+ + D +GP+IR G ++ V L +G+ ++++T D + + I++DY+
Sbjct: 61 ----GITVLQDLQGPKIRVGAVQNDS---VMLAEGDEVRVST--DTPRESTNEHIFIDYE 111
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
+ + G RI IDDGL+ + + L T+ GG L SRKGVNLP + P ++
Sbjct: 112 ALARDAREGERILIDDGLLELRVIETNGSQLRATVVEGGPLRSRKGVNLPDLQASTPPMT 171
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
EKD DL G+E VD++ SF++ + + + + E GK
Sbjct: 172 EKDLKDLELGLELEVDVVALSFVQERSDVEALVHRIEETGK 212
Score = 41.9 bits (94), Expect = 0.032
Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAK 1098
G++ +++K E Q + N + I+ DGIMVARG LGI +P + P K +I K
Sbjct: 211 GKKTSVVAKIEKPQAVHNIDEILEVVDGIMVARGDLGIEMPMEEVPGTQKRLIRK 265
>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
proteobacterium MLMS-1
Length = 493
Score = 137 bits (331), Expect = 6e-31
Identities = 78/220 (35%), Positives = 121/220 (55%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GPA+ + + E GMNVAR+N SHGS E+H I N + K Y+
Sbjct: 16 RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
SLA+ LDT+G EIR+G L+ ++EL+ G+ + LTT Q + + V +
Sbjct: 74 ----SLAVLLDTRGAEIRSGDLK----QDLELRVGDGLTLTTRR--QAELEPGCVEVSHD 123
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
V PG+ I +D G++ + V + C + G+LGSR+ +N+ G DLPA++
Sbjct: 124 GFVAEVTPGDIILVDGGMLRLKVVEVGRTDVRCQSLDEGVLGSRRHLNIRGKSADLPAIT 183
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
E+D +D+ FG+EQ VD I SF+R + ++ L +G
Sbjct: 184 EQDWADIEFGMEQRVDFIALSFVRTAEPIQVVQQHLAARG 223
Score = 40.7 bits (91), Expect = 0.074
Identities = 19/57 (33%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKN-MIAKC 1101
+G ++++K E+ + + II +DG+MVARG LG +P + P ++ ++AKC
Sbjct: 222 RGVTMEVMAKIESAASIAQLDAIIAAADGVMVARGDLGAELPYEEVPLLQDEIVAKC 278
>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 579
Score = 137 bits (331), Expect = 6e-31
Identities = 77/229 (33%), Positives = 124/229 (54%)
Frame = +2
Query: 263 SKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEK 442
SK + R + +CT GP++ ++ E GMNVARMN SHG H H + I + K
Sbjct: 104 SKPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVK 159
Query: 443 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 622
Y+A+ ++AI LDTKGPE+R+G L + L G+ T
Sbjct: 160 EYNAQTKDN-TIAIMLDTKGPEVRSGDLP----QPIMLDPGQEFTFTIERGVS---TPSC 211
Query: 623 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 802
+ V+Y + N V+ G+ + +D G++S + +S + D++ C + +GG L SR+ +N+ G
Sbjct: 212 VSVNYDDFVNDVEAGDMLLVDGGMMSFMVKSKTKDSVKCEVVDGGELKSRRHLNVRGKSA 271
Query: 803 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
LP+++EKD D+ FGVE VD SF+++ +HE++ L G +I
Sbjct: 272 TLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKKYLQNSGADI 320
Score = 38.3 bits (85), Expect = 0.39
Identities = 19/46 (41%), Positives = 26/46 (56%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
G + +I K E+ + N + II SDG MVARG LG +P + P
Sbjct: 317 GADIHVIVKIESADSIPNLHSIITASDGAMVARGDLGAELPIEEVP 362
>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
bacterium TAV2
Length = 480
Score = 136 bits (330), Expect = 8e-31
Identities = 75/219 (34%), Positives = 126/219 (57%), Gaps = 2/219 (0%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
IR + + T GPA+ + +L + G +VAR+N +H +HE+ IR RE K +
Sbjct: 10 IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD--TIYV 631
+G +AI +D KGPEIRTG + S+ +ELK GE T + + + ++ V
Sbjct: 66 VGR--EIAIMMDIKGPEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDV 119
Query: 632 DYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLP 811
+YK++ N ++ G+ + +D+GLI + + C + G L SR+ +NLPG+ V+LP
Sbjct: 120 NYKDLVNDIRVGDTVLVDNGLIRLEVLEKQNTRIRCRVLIPGELKSRRHINLPGVKVNLP 179
Query: 812 AVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
+++EKDK+DL G+ +G+D + SF+R A + +R +L
Sbjct: 180 SLTEKDKTDLAVGLIEGIDFVALSFVREAADIQLLRDVL 218
Score = 37.9 bits (84), Expect = 0.52
Identities = 17/41 (41%), Positives = 25/41 (60%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
II+K E+ + N + I+ +D +MVARG LGI P + P
Sbjct: 227 IIAKIEDQSAIANLDEIVRTTDALMVARGDLGIECPFEELP 267
>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 478
Score = 136 bits (328), Expect = 1e-30
Identities = 77/211 (36%), Positives = 114/211 (54%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPAS + + ++ GM++ARMNFSHG+H+ H R+ E+ + F
Sbjct: 15 VCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------FP 68
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
L I D +GP+IRTG L+ + L K + I++ SD G+ I Y N+
Sbjct: 69 LGIMADLQGPKIRTGKLKLNS---ILLHKNQEIEIVPDSDIL--GDEHKIGCTYPNLIRD 123
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
++ ++I IDDG + + S +++ + GG+L S KG+NLPG P+ PA+SEKD
Sbjct: 124 IQEEDKILIDDGKLILKVISKKSNSAILKVIVGGILWSNKGINLPGTPISAPALSEKDIE 183
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
DL F + GVD SF+R GA L R L
Sbjct: 184 DLKFALSLGVDYAALSFVRTGADLELARSYL 214
Score = 38.3 bits (85), Expect = 0.39
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAK 1098
+I+K E + + N II +DGIM+ARG LG+ I ++ P K +I K
Sbjct: 221 LIAKIERPEAIGNIEEIIERADGIMIARGDLGVEIDTEKVPILQKELIYK 270
>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
uncultured delta proteobacterium DeepAnt-32C6
Length = 466
Score = 136 bits (328), Expect = 1e-30
Identities = 79/217 (36%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPA+ + ++ GM+ AR+NFSHG+ + HA RE + +
Sbjct: 1 MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVREL----ATE 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
G P +A+ D GP+IR G G VEL +G LTT G ++Y
Sbjct: 57 AGRP--IALLADLCGPKIRVGRFPEGA---VELVEGTAFTLTTRD---VAGTDKQASINY 108
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+ V PG+ I IDDGLI ++ + V + C +E GGML RKG+N+PG + PA+
Sbjct: 109 AALPQDVDPGDAIMIDDGLIRLVVREVEGPDIHCIVEVGGMLSERKGINVPGSALSTPAL 168
Query: 818 SEKDKSDLLFGVEQ-GVDMIFASFIRNGAXLHEIRGI 925
++KDK DL F V+ GVD I SF+R A + E + +
Sbjct: 169 TDKDKRDLAFAVDTIGVDWIALSFVRTAADILEAKSL 205
>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
organisms|Rep: Pyruvate kinase - Uncultured methanogenic
archaeon RC-I
Length = 583
Score = 135 bits (327), Expect = 2e-30
Identities = 77/224 (34%), Positives = 120/224 (53%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPA + +L GMNVAR+N SH HE+ +TI N R ++
Sbjct: 1 MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIRMVSEA---- 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
+G P + I +D +GP+IR G L+ LK G T LTT G++ + V +
Sbjct: 57 IGKP--IGILMDLQGPKIRVGTLQ----QPANLKPGGTFTLTTRD---VPGDSQEVNVPF 107
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
K + V G + +DDGLI + +V+ + + GG L S+KG+NLP + +P++
Sbjct: 108 KELPQSVSTGQTLLLDDGLIELKVDAVTETDIRTKVVRGGELKSKKGINLPQSTIRIPSI 167
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
+EKD DL FG+E VDMI SF+R + ++R + + +I
Sbjct: 168 TEKDVRDLEFGIEHEVDMIAMSFVRKPQDVLDLRKKIEDNDSDI 211
Score = 49.2 bits (112), Expect = 2e-04
Identities = 26/51 (50%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNM-IAKC 1101
IISK E H+ + N + II DG+MVARG LGI IP P + M I+KC
Sbjct: 213 IISKIEKHEAVKNIDGIIDVVDGVMVARGDLGIEIPMAEVPIVQKMIISKC 263
>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
psychrophila|Rep: Pyruvate kinase - Desulfotalea
psychrophila
Length = 581
Score = 134 bits (325), Expect = 3e-30
Identities = 79/215 (36%), Positives = 118/215 (54%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GP S++V + ++ GMNVAR+N SHG E + I N +EA K
Sbjct: 7 IATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKLAEK------D 60
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
AI LD +GPEIR +E ++ L GE + +T + E + I +Y +
Sbjct: 61 TAILLDNRGPEIRVSEME----EDIHLVDGEELVITNRA---ETVSPSRITTNYPQLAGD 113
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V+ G+RI +DDG +++ ++ + + + GG+L SRK V LP V+LP++SEKDK
Sbjct: 114 VQVGSRILLDDGKLALEVLAIEDEEVITKVIAGGILSSRKRVALPDNEVNLPSLSEKDKE 173
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
D+ FGVEQ VD I ASF+R + +R I+ + G
Sbjct: 174 DIAFGVEQDVDFIAASFVRQAGDVWAVRKIIEDNG 208
Score = 50.0 bits (114), Expect = 1e-04
Identities = 23/54 (42%), Positives = 35/54 (64%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G + +II+K EN QG+ N + I+ ++GIMVARG LG+ +P + P + I K
Sbjct: 208 GGDQEIIAKIENRQGVNNLDEILQAANGIMVARGDLGVEVPAEEVPIIQKSIIK 261
>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
isozyme G, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 562
Score = 134 bits (324), Expect = 4e-30
Identities = 74/230 (32%), Positives = 125/230 (54%), Gaps = 3/230 (1%)
Frame = +2
Query: 248 GLDIDSKSSYI---RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETI 418
G + +S Y+ R + +CT GP++ + ++ E GMNVAR+N SHG H H TI
Sbjct: 77 GYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTI 136
Query: 419 RNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 598
+E + K+ +AI LDTKGPE+ + G + LK+G+ +
Sbjct: 137 DLVKEYNAQFEDKV-----IAIMLDTKGPEV----ISGDVPKPILLKEGQEFNFSIKRGV 187
Query: 599 QEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKG 778
+ DT+ V+Y + N V+ G+ + +D G++S+ +S ++D + C + +GG L SR+
Sbjct: 188 STE---DTVSVNYDDFINDVEAGDILLVDGGMMSLAVKSKTSDIVKCEVIDGGELKSRRH 244
Query: 779 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
+N+ G LP+++EKD D+ FGV VD SF+++ +HE++ L
Sbjct: 245 LNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYL 294
Score = 39.5 bits (88), Expect = 0.17
Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKCXGLE 1113
+I K E+ + N + II SDG MVARG LG +P + P +++I +C ++
Sbjct: 303 VIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQ 357
>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
Pyruvate kinase - Anabaena sp. (strain PCC 7120)
Length = 476
Score = 132 bits (320), Expect = 1e-29
Identities = 80/226 (35%), Positives = 126/226 (55%), Gaps = 1/226 (0%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + ICT GPA+ L +E GMNVAR+NFSHG++++HA+T + R+ SA
Sbjct: 1 MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQI----SAD 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA-DTIYVD 634
P +AI D GP+IR G L G + ++ G+ + QEKG++ D + +
Sbjct: 57 RQKP--VAIMQDLCGPKIRLGTLPPEG---LMVEAGQEVTFVL----QEKGSSLDELPLP 107
Query: 635 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 814
+ +V+PG I I+DG + +I AD + + GG+L +RKGVNLP + + +
Sbjct: 108 LPTLFAMVRPGEPILINDGRVKLIVTDRDADRIRAIAKIGGLLSTRKGVNLPATRLPVSS 167
Query: 815 VSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
++EKD DL FG++ VD + SF+R+ L + ++ GK IR
Sbjct: 168 ITEKDLQDLRFGIDLSVDWVAVSFVRSPYDLEPAQRMIEAAGKTIR 213
Score = 38.7 bits (86), Expect = 0.30
Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G+ ++I+K E + + + II +D IM+ARG LG+ +P P K++I +C
Sbjct: 209 GKTIRVIAKIERPEAVEQIDSIIDVADAIMIARGDLGVEMPIHEVPLIQKDIIRRC 264
>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
pacifica SIR-1
Length = 485
Score = 132 bits (318), Expect = 2e-29
Identities = 76/224 (33%), Positives = 122/224 (54%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GPAS + ++ M+ G++ R+NFSHGSHE HA+ RE + S +
Sbjct: 6 LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
+A+ D +GP+IR G + G + L+ GET+ T D + + + +DY
Sbjct: 65 -----PVAVLGDLQGPKIRVGKIPDPG---MTLETGETLVFLT--DPTAEISQGRVTIDY 114
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+ K G R+ +DDG + ++A + + NGG+L +RKGVNLP + LP++
Sbjct: 115 PTLDEEAKVGERVLMDDGELEARITEINAGEVHAEMLNGGVLKARKGVNLPDSDLLLPSL 174
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
++KD DL F +E GVD + SF+R L E R I+ E G+ +
Sbjct: 175 TDKDAKDLRFALELGVDFVALSFVRRVEDLEECRKIMNEVGRTV 218
>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
Pyruvate kinase - Rhodopirellula baltica
Length = 476
Score = 131 bits (316), Expect = 4e-29
Identities = 74/223 (33%), Positives = 118/223 (52%), Gaps = 4/223 (1%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPA+ + L +E G++V R+N +HG+ E+ E + R+ K S +
Sbjct: 10 IATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISRHV----- 64
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS--SDYQ--EKGNADTIYVDYKN 643
A+ +D KGPEIRTG +E +ELK G+ + L T +D E + V+Y
Sbjct: 65 -AVMMDVKGPEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVSVNYLG 119
Query: 644 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 823
+ + + I +D GL+ A T+ C + G+L SR+ +NLPG+ V+LPA+++
Sbjct: 120 LPGAIDLDSTILVDSGLLHWHVLKKDATTVRCRVITPGVLESRRHINLPGVQVNLPAITD 179
Query: 824 KDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KD++DL GV+ G+D + SF+R + +R L E G R
Sbjct: 180 KDRTDLAAGVKAGIDFVALSFVRQAEDVRTLRAFLDEHGSPAR 222
Score = 44.8 bits (101), Expect = 0.005
Identities = 25/56 (44%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPK-NMIAKC 1101
G +IISK E+ G+ N II +SD IMVARG LG+ I R P + ++I C
Sbjct: 218 GSPARIISKIEDQAGVRNMKAIIRQSDAIMVARGDLGVEIDYHRLPLVQTDLIRAC 273
>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 477
Score = 130 bits (315), Expect = 5e-29
Identities = 75/226 (33%), Positives = 127/226 (56%), Gaps = 2/226 (0%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GPA+ + + + G++V R+NFSHG+H+ H + R REA +A+
Sbjct: 3 VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
G ++AI D +GP+IRTG +EGG EL +G + + D+ G+A + Y
Sbjct: 59 AGR--NVAIMQDLQGPKIRTGEVEGG----TELVEGSRV-VIAPGDF--VGDASRLSTSY 109
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGMLGSRKGVNLPGIPVDLPA 814
+ VKPG+R+ IDDGLI + +S+ + + C + GG + S KG+N P + +
Sbjct: 110 DRLAQDVKPGHRLLIDDGLIGLRVESIKENGEIVCEVLEGGPVSSHKGLNFPDSSLSISG 169
Query: 815 VSEKDKSDLLFGVEQ-GVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
++EKD DL FG+E+ D + SF+R G + +++ + E G ++
Sbjct: 170 LTEKDLEDLRFGLEELRPDWVAISFVRTGEEVLDVKERIRELGGDV 215
Score = 47.2 bits (107), Expect = 8e-04
Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G + +ISK E H+ + N +I SDG+MVARG L + + +R P K ++A+C
Sbjct: 212 GGDVPVISKIEKHEAIDNIEEVIEASDGVMVARGDLAVELSAERVPIEQKRIVARC 267
>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
Pyruvate kinase - Chlamydia trachomatis
Length = 485
Score = 130 bits (314), Expect = 7e-29
Identities = 76/216 (35%), Positives = 116/216 (53%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
ICT GPA+ +L ++ GMNVAR+NFSHG+HE H TI +E + L
Sbjct: 8 ICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPL----- 62
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
AI LDTKGPEIR G +E + ++++ G+ + L + K + T+Y +
Sbjct: 63 -AIMLDTKGPEIRLGQVE----SPIKVQPGDRLTLVSKEILGSKESGVTLYPSC--VFPY 115
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V+ + IDDG I + + + +N G + S K +++ I V LP ++EKD +
Sbjct: 116 VRERAPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIKDIDVALPFMTEKDIA 175
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
DL FGVEQ +D+I ASF+R + +R +L G+
Sbjct: 176 DLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGR 211
Score = 43.2 bits (97), Expect = 0.014
Identities = 21/49 (42%), Positives = 29/49 (59%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
II+K ENH G+ N I +DGIM+ARG LGI + P + +A+
Sbjct: 216 IIAKIENHLGVQNFQEIARAADGIMIARGDLGIELSIVEVPGLQKFMAR 264
>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Pyruvate kinase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 477
Score = 130 bits (313), Expect = 9e-29
Identities = 72/223 (32%), Positives = 114/223 (51%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GPA+ +VL ++ GM+VAR+NFSH +H H+ RE +
Sbjct: 4 RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G + D +GP+IR G G V GE + +TT G+ D + Y
Sbjct: 64 G------VLADLQGPKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYA 111
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
++ V+ G+R+ +DDG + + +V + C + +GG + KG++LP IPV +P +S
Sbjct: 112 GLSQDVRAGDRLLVDDGRVDLRVVAVDGPDIRCEVVDGGPVSDHKGISLPNIPVSVPPLS 171
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
+KD DL F +E G DMI SF+R + I+ E G+ +
Sbjct: 172 DKDIEDLKFALELGADMIAMSFVRAPEEVELAHKIMDEVGRRV 214
Score = 37.1 bits (82), Expect = 0.91
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G +I+K E + + + I+ DG+MVARG LG+ +P ++ P + IA C
Sbjct: 211 GRRVPVIAKLEKPEAVSDLPAIVEAFDGLMVARGDLGVEMPLEQIPLVQRRAIALC 266
>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 485
Score = 129 bits (312), Expect = 1e-28
Identities = 71/206 (34%), Positives = 116/206 (56%)
Frame = +2
Query: 302 TXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLA 481
T GPAS + +L + G++VAR+NFSHG H E I N R A S + G ++A
Sbjct: 13 TIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR--AVA 66
Query: 482 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVK 661
+ D GP++R G ++ + + L+ G+ LTT S G+ + + + VVK
Sbjct: 67 VLADLPGPKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQVVK 120
Query: 662 PGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDL 841
PG+R++++DGL+ ++ + + + C + GG L SRKG+NLPGI + + A +E D+ L
Sbjct: 121 PGDRLYLNDGLVHLLVERIEGTDVHCVVAVGGELRSRKGLNLPGINLGISAFTEHDRDCL 180
Query: 842 LFGVEQGVDMIFASFIRNGAXLHEIR 919
F +E GVD + SF++N + +R
Sbjct: 181 KFALENGVDAVSQSFVQNAHDIELVR 206
Score = 38.7 bits (86), Expect = 0.30
Identities = 19/41 (46%), Positives = 25/41 (60%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIP 1059
G I +K E + + N + I+ SDGIMVARG LGI +P
Sbjct: 213 GHHPFIFAKIERAEAVQNYDEILRASDGIMVARGDLGIEVP 253
>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Deinococcus radiodurans
Length = 482
Score = 129 bits (311), Expect = 2e-28
Identities = 76/224 (33%), Positives = 115/224 (51%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPASR+ VL ++ G+NV R+NFSHG E H +T++ R+ S +
Sbjct: 6 RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G I D +GP+IR G G V L G+ +T + +GNA+ + YK
Sbjct: 66 G------ILQDLQGPKIRVGRFAEGS---VTLNPGQKFVITMD---EVEGNAERVGSTYK 113
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
+ V PG + +DDG +S+ V + + T+ GG L + KG+N+P + +PA+S
Sbjct: 114 GLAGDVTPGMTLLLDDGNMSLRVDHVRGNDIQTTVLIGGTLKNNKGINVPEADLTVPALS 173
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
EKD D+ FG GVD + SF+R+ L R L G +
Sbjct: 174 EKDVQDMEFGASLGVDWVALSFVRSRDDLLLARHYLARFGSRAK 217
Score = 36.3 bits (80), Expect = 1.6
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G ++++K E Q + I+ E DG+MVARG LG+ + ++ P K +I C
Sbjct: 213 GSRAKLMAKIEKPQAVDRFADILKEVDGVMVARGDLGVEMRPEQVPTIQKRIIRMC 268
>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 619
Score = 129 bits (311), Expect = 2e-28
Identities = 79/218 (36%), Positives = 115/218 (52%), Gaps = 2/218 (0%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPAS N A+L + G R+NFSHG HE H +IR R+ + L
Sbjct: 8 RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G +AI D +GP+IR G G + LK G+ LT+ G+ + +V Y
Sbjct: 64 G--IQVAILQDLQGPKIRLGKFAEGS---ITLKAGDPFVLTSKPVL---GSQERSWVTYD 115
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 814
+ V G I IDDG + + ++V A L C GG L + KGVN PG+ + + A
Sbjct: 116 KLAQEVPEGATILIDDGRVEMRVEAVDPEAGELFCRTIVGGTLSNNKGVNFPGVRLSIRA 175
Query: 815 VSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
V+ KDK DL FG+ QGVD + SF+R+ + + E+R ++
Sbjct: 176 VTPKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELI 213
Score = 40.3 bits (90), Expect = 0.097
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKCXGL 1110
II K E H+ + I+ SDG+MVARG LG+ +P + P K +IA L
Sbjct: 230 IIVKIEKHEAIEQLPQILALSDGVMVARGDLGVELPAEEVPILQKRVIALANSL 283
>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
NBC37-1)
Length = 488
Score = 127 bits (306), Expect = 7e-28
Identities = 71/221 (32%), Positives = 120/221 (54%), Gaps = 2/221 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPA+ + + M G+N+ R+NFSHG+HEYH+E + R+A + G
Sbjct: 8 IATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG---- 63
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS--DYQEKGNADTIYVDYKNIT 649
I D GP+IR G+LE + LK G+ ++ Y+ K + ++ +I
Sbjct: 64 --ILQDISGPKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDIL 117
Query: 650 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 829
+ ++ G I++ DG+I + + SAD + IEN GML SRKGVN P + + ++EKD
Sbjct: 118 DQLEVGESIYMYDGIIRAVVKEKSADMVKVEIENNGMLSSRKGVNFPNTHLGINVLTEKD 177
Query: 830 KSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
K D+L+G++ VD + SF+++ + R ++ G +++
Sbjct: 178 KKDILWGIKHEVDFMAISFVQHQKDMTAAREVITSNGGSVQ 218
Score = 44.4 bits (100), Expect = 0.006
Identities = 23/54 (42%), Positives = 31/54 (57%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G Q+++K E + N + I+ SDGIMVARG LGI IP P + M+ K
Sbjct: 214 GGSVQLLAKIEKFDAIENIDAILEASDGIMVARGDLGIEIPYYDVPLIQKMLIK 267
>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
Pyruvate kinase - Monocercomonoides sp. PA203
Length = 516
Score = 126 bits (305), Expect = 9e-28
Identities = 75/230 (32%), Positives = 123/230 (53%), Gaps = 2/230 (0%)
Frame = +2
Query: 269 SSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSY 448
+S+ L+ + T GPA+ + + G+NV RMNFSHG+HE+H + + R+ +
Sbjct: 32 ASFTPLTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED- 90
Query: 449 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 628
LG +AI D +GP++RT GG ++ +K+G+ + + S + + G T +
Sbjct: 91 ---LGK--EVAIIADLQGPKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKF 142
Query: 629 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV-D 805
NV +P + IDDGLI +I Q + + L C +E GG + KG+NLP +
Sbjct: 143 TPMITHCNVGEP---VLIDDGLIRLIVQEKNPNELVCLVEQGGDVKDHKGINLPATDLGP 199
Query: 806 LPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
LPA++EKD D F ++ VD SF+R + ++R ++ KGK +R
Sbjct: 200 LPALTEKDIEDAKFVLDTLEVDFFALSFVRKPQDVLDLRHLIEAKGKEMR 249
Score = 38.3 bits (85), Expect = 0.39
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
KG+E +II K E + + N + I+ SD MVARG L + + + P K++I C
Sbjct: 244 KGKEMRIIVKIEKPEAIKNLDEILAVSDACMVARGDLAVEVGTAKVPCLQKHIIRHC 300
>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
Pyruvate kinase - Parabacteroides distasonis (strain
ATCC 8503 / DSM 20701 / NCTC11152)
Length = 485
Score = 126 bits (304), Expect = 1e-27
Identities = 76/219 (34%), Positives = 119/219 (54%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T +VA + + GMNV R+N +H E + N R + S ++G
Sbjct: 8 VATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSDRIG---- 59
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
I +DTKGPE+RT + K GE +K+ + D QE + D I V YKN N
Sbjct: 60 --ILMDTKGPEVRTTTTVN--KEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVND 113
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ G+ I IDDG + + S D L C I+N LGSRK VN+PG+ ++LP+++EKD++
Sbjct: 114 LAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVPGVRINLPSLTEKDRN 173
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
++L+ ++ +D I SF+RN + +I+ IL E+ I+
Sbjct: 174 NILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIK 212
Score = 45.6 bits (103), Expect = 0.003
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNM-IAKC 1101
+II+K EN +G+ N I+ + G+M+ARG LGI +P ++ P + M I KC
Sbjct: 212 KIIAKIENQEGVDNIEEILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKC 263
>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
Length = 478
Score = 126 bits (304), Expect = 1e-27
Identities = 74/215 (34%), Positives = 117/215 (54%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPA+++ ++ + GMNVAR+N SH + H + + ++ K L PF
Sbjct: 13 VCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF- 67
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
AI LD +GP+IRTG E + +V L++G+ LT + GN + + ++Y+ +
Sbjct: 68 -AILLDLEGPKIRTGKFE---TDQVMLEEGQKFILTIE---EIVGNKERVSINYRELPKE 120
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
VK G+ I +DDG I ++ S + + + GG + R+G+N+PGI + LP ++EKD
Sbjct: 121 VKKGDFILLDDGKIRLVVVSSNEKEIVTKVVTGGSITHRRGINVPGIDISLPPLTEKDME 180
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
L VE VD I SF+R + R IL E G
Sbjct: 181 YLNKAVEWNVDYIAQSFVRKAEDITRTRRILTELG 215
Score = 42.7 bits (96), Expect = 0.018
Identities = 20/41 (48%), Positives = 27/41 (65%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
II+K E Q + N II E+DG+MVARG LG+ P ++ P
Sbjct: 221 IIAKIETLQALDNLESIIEEADGVMVARGDLGVEAPVEQIP 261
>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
longum
Length = 509
Score = 126 bits (303), Expect = 2e-27
Identities = 70/231 (30%), Positives = 124/231 (53%), Gaps = 2/231 (0%)
Frame = +2
Query: 263 SKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEK 442
++ +++R + + T GP++ + L +E GM+VAR+N SHG+ E H + N R+A +
Sbjct: 25 NRQAFMRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASE 84
Query: 443 SYSAKLGSPFSLAIALDTKGPEIRTGLLE--GGGSAEVELKKGETIKLTTSSDYQEKGNA 616
+ ++A +D +GP+IR G + G +V+L+ G+ +TT +G+
Sbjct: 85 ATGR------NVAALVDLQGPKIRCGWFKKNADGEDKVQLQLGQEFVITTDD---VEGDE 135
Query: 617 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 796
+K + PG+ I IDDG + + V + + + G + S KG+NLPG+
Sbjct: 136 HITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKVEGNNVYTKVVVAGPVSSHKGINLPGV 195
Query: 797 PVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
V LPA++EKD++DL + + G D+I SF+R + I+ E+G+ I
Sbjct: 196 AVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMDEEGRRI 246
Score = 35.5 bits (78), Expect = 2.8
Identities = 16/47 (34%), Positives = 24/47 (51%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
+G II+K E Q + N I+ DG+M ARG + + P + P
Sbjct: 242 EGRRIPIIAKIEKPQALENLEEIVKTFDGVMAARGDMAVECPLEEVP 288
>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
Phytoplasma|Rep: Pyruvate kinase - Onion yellows
phytoplasma
Length = 446
Score = 126 bits (303), Expect = 2e-27
Identities = 76/219 (34%), Positives = 121/219 (55%), Gaps = 2/219 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
ICT GPAS + +L ++ G+NVAR NFSH +E ++ K+ S KL +
Sbjct: 7 ICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK--N 60
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ LDTKGPEIRT +G V ++K +K++ + + GNA V Y N+ N
Sbjct: 61 TGLMLDTKGPEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYNE 113
Query: 656 VKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 829
+K G+ + IDDG +S ++ + + L +N + SR+GVN+P + +++ +S KD
Sbjct: 114 LKVGDMVNIDDGYLSLEVVGKDEAKQQLVTKAKNTHSIKSRRGVNVPKVNLEMDFISPKD 173
Query: 830 KSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
D++F +Q D I ASF+R + +IR IL E+G +
Sbjct: 174 YQDIVFAAQQDFDYIAASFVRRAQDVKDIRKILQEQGNS 212
Score = 53.2 bits (122), Expect = 1e-05
Identities = 29/52 (55%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
QIISK EN +G+ N II ESDGIMVARG LGI + + P MI KC
Sbjct: 215 QIISKIENQEGVDNLEEIIQESDGIMVARGDLGIEVDGELVPLYQTRMITKC 266
>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
MC-1)
Length = 569
Score = 125 bits (301), Expect = 3e-27
Identities = 70/217 (32%), Positives = 110/217 (50%), Gaps = 1/217 (0%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPA +V + +E G++VAR+N SHG H+ H E I N REA + ++
Sbjct: 3 RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREASRIAKREV 62
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDY 637
A+ D +GP+IR G L+ + L+KG+ + + K D I Y
Sbjct: 63 ------ALLCDLQGPKIRVGHLD----EPLRLEKGQQWAIIPEGSHPPKLKCDGIIPCTY 112
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+ PG RI DDG + L IE+GG+L S KG+N+P + P++
Sbjct: 113 AGLAKDAVPGCRILFDDGYLQARAIGTEEGALLVNIEHGGLLKSHKGINMPDASISAPSL 172
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
+ KD+ DL FGV+ VD + SF+R+ + ++ +L
Sbjct: 173 TTKDQQDLFFGVKHDVDYVALSFVRSAKCVQNVKFML 209
Score = 36.7 bits (81), Expect = 1.2
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
II+K E + + N + II DGIM+ARG + + I R P + +I KC
Sbjct: 218 IIAKIERPEAIRNIDEIIKVVDGIMIARGDMAVEIGNHRVPSVQRQIIQKC 268
>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
Pyruvate kinase - Thermococcus litoralis
Length = 220
Score = 125 bits (301), Expect = 3e-27
Identities = 70/218 (32%), Positives = 123/218 (56%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPAS+ + ++ GM+VAR+NFSHG+ E HA+TI R+ + ++
Sbjct: 15 IATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERRV----- 69
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
AI D G ++R G ++G V L+KG+ + LTT +G+ TI V++K++ +
Sbjct: 70 -AILGDLPGLKMRVGKIKGDS---VTLRKGDKVVLTTRDI---EGDETTIPVEFKDLPKL 122
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V G+ I++ DG I + + V + + C + NGG+L S KG+N+P + + A++ +D
Sbjct: 123 VSKGDTIYLSDGYIMLRVEEVRENEVECVVVNGGILFSHKGINIPKANLPIEAITPRDFE 182
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
+ F +E GVD I SF+ + + +++ L +K ++
Sbjct: 183 IIEFAIEHGVDAIGLSFVGSVYDVLKVKSFLEKKSADL 220
>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
Pyruvate kinase - Flavobacteriales bacterium HTCC2170
Length = 480
Score = 123 bits (296), Expect = 1e-26
Identities = 69/224 (30%), Positives = 120/224 (53%), Gaps = 1/224 (0%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
I+ + + T GPA+ V+ ++ G++V R+NFSH +E ++ RE + +
Sbjct: 4 IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
++AI D +GP++R G++ G EV + G+ I T ++ GN++ +Y++Y
Sbjct: 63 -----NIAILGDLQGPKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNY 111
Query: 638 KNITNVVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 814
V PG RI +DDG L+ + + D + + GG L S+KGVNLP + LPA
Sbjct: 112 AAFPKDVNPGERILLDDGKLMFEVVSTNKKDKVRAKVIQGGPLKSKKGVNLPNTNISLPA 171
Query: 815 VSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
++EKD D F + VD I SF+R+ + +++ I+ E ++
Sbjct: 172 LTEKDVKDAKFAISLDVDWIALSFVRHSQDIIDLQNIIKEHAEH 215
Score = 38.7 bits (86), Expect = 0.30
Identities = 19/46 (41%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +1
Query: 943 EHQI--ISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
EH+I I+K E + + N + I+ DG+MVARG LG+ +P P
Sbjct: 214 EHKIPIIAKIEKPEAVENIDKIVSYCDGLMVARGDLGVEVPAHEVP 259
>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
B - Apis mellifera
Length = 538
Score = 122 bits (294), Expect = 2e-26
Identities = 67/245 (27%), Positives = 122/245 (49%), Gaps = 2/245 (0%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYH 406
++L+H L+I+S RL+ + T G + + + M G N+ R+N +H + ++H
Sbjct: 21 TRLEHNINLNINSSPKLARLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLNMAHETDKWH 80
Query: 407 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA--EVELKKGETIKL 580
T+++ R+A + + L +A++ +GPEIR G G ++ +LK+G+ +KL
Sbjct: 81 TATVQSVRKAGNTMYEFTSEIYPLGVAINLQGPEIRAGAFRGDKTSLGYAKLKEGKMVKL 140
Query: 581 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGM 760
T + G A+ +V Y N+ + + G+RI ID G + + + +TC I GG+
Sbjct: 141 VTQDIAKRAGRANCFWVSYPNLPKICQVGDRILIDRGAVLLQVTCIHEQAITCKIIKGGI 200
Query: 761 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
+ K + L V LP +SEKD + + + D + + +RN L+ I+ E
Sbjct: 201 VKDGKLIQLLDSLVPLPQISEKDIAHVKWASHLECDFLIMNHVRNEKVLYTIKSRFKEMS 260
Query: 941 KNIRS 955
I S
Sbjct: 261 MRIIS 265
>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
lacusprofundi ATCC 49239
Length = 613
Score = 122 bits (294), Expect = 2e-26
Identities = 74/235 (31%), Positives = 121/235 (51%), Gaps = 3/235 (1%)
Frame = +2
Query: 245 CGLDID-SKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIR 421
CG + +KS +R + +CT GPAS + + + GM+V R+N SHG+ + E I
Sbjct: 17 CGFFLSCAKSGDMRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNASHGTTAHREEVIE 76
Query: 422 NCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD-- 595
R + ++ P LA+ +D KGPE+RT L+ E+I L T S+
Sbjct: 77 RARAVDN----EIDDP--LAVMVDLKGPEVRTAELD------------ESISLATGSEVT 118
Query: 596 YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRK 775
+ E +A V + PG+ + +DDG I + V +++ T+ +GG L SRK
Sbjct: 119 FVEGDDATPERVGLTHSIAAAGPGDTVLLDDGRIECRVERVDGESVVATVVSGGKLSSRK 178
Query: 776 GVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
GVNLPG+ +D+ ++ +D+++L D + ASF+RN ++ I L E+G
Sbjct: 179 GVNLPGVAIDVDLITAEDEAELDLAARTNADFVAASFVRNANDVYRIADALEERG 233
Score = 43.2 bits (97), Expect = 0.014
Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G++ I++K E + N + II +DG+MVARG LG+ P + P K +I KC
Sbjct: 234 GDDIPIVAKIERAGAVENLDGIIDAADGVMVARGDLGVECPLEDVPVIQKRIIRKC 289
>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
Pyruvate kinase - Bacteroides fragilis
Length = 485
Score = 122 bits (293), Expect = 2e-26
Identities = 70/210 (33%), Positives = 111/210 (52%)
Frame = +2
Query: 323 NVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKG 502
+V + + GMNV RMN +H S E I N R +AI +DTKG
Sbjct: 18 DVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----------IAILMDTKG 67
Query: 503 PEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFI 682
PE+RT + + + GE +K+ D + + I V Y N + + G I I
Sbjct: 68 PEVRTT----ANADPILYQIGEKVKIVGDPDRET--TRECIAVSYPNFVHDLNVGGTILI 121
Query: 683 DDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQG 862
DDG + + + + L C ++N LGSRK VN+PG+ ++LP+++EKD++++L+ +E+
Sbjct: 122 DDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVRINLPSLTEKDRNNILYAIEKD 181
Query: 863 VDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
+D I SF+RN + +IRGIL +IR
Sbjct: 182 IDFIAHSFVRNRQDVLDIRGILDAHNSDIR 211
Score = 51.2 bits (117), Expect = 5e-05
Identities = 25/52 (48%), Positives = 36/52 (69%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNM-IAKC 1101
+II+K EN +G+ N + I+ +DG+MVARG LGI +P +R P + M I KC
Sbjct: 211 RIIAKIENQEGVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQRMLIRKC 262
>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
Pyruvate kinase - Mesoplasma florum (Acholeplasma
florum)
Length = 478
Score = 120 bits (290), Expect = 6e-26
Identities = 76/226 (33%), Positives = 118/226 (52%), Gaps = 1/226 (0%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
++ + I T GP++ + E GM R+NFSHG +E I ++ + +
Sbjct: 10 VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
LG P S I LDTKGPEIR G G EV + TI S ++ + + V Y
Sbjct: 66 LGKPVS--ILLDTKGPEIRVGKFVDG-KQEVTANQSITIYTDAESFKNKECLSGEMTVAY 122
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+++ +K G+ I IDDG + + + V + N ++ + K VNLPG+ +P +
Sbjct: 123 -DMSVDLKIGDTILIDDGKLEMTVEEVKPGVVKAIAFNNHLVKTNKRVNLPGVDFSMPFL 181
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE-KGKNIR 952
++KD +D+ +GVEQGVD I ASF+ + + EIR IL E G +I+
Sbjct: 182 AQKDINDIKYGVEQGVDYIAASFVNSAENVKEIRDILAEANGSDIQ 227
Score = 51.6 bits (118), Expect = 4e-05
Identities = 29/56 (51%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G + QIISK E+ G+ N + II SDGIM+ARG LG+ IP P K MI KC
Sbjct: 223 GSDIQIISKIESQVGIDNIDAIIEASDGIMIARGDLGLEIPYYDVPYWEKIMIRKC 278
>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
Epsilonproteobacteria|Rep: Pyruvate kinase -
Nitratiruptor sp. (strain SB155-2)
Length = 458
Score = 120 bits (288), Expect = 1e-25
Identities = 74/217 (34%), Positives = 118/217 (54%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GP+S + + + G+NV R+NFSH H+ H +I+ RE K KLG+
Sbjct: 5 VATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLGT--K 56
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
AI D GP+IR G ++G +EL KG+ I+L + K D + + Y I +
Sbjct: 57 TAILQDISGPKIRIGEVDG----ILELSKGDKIRLVKT---HPKSKYD-LTLSYPQIIDD 108
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
++ G +F DG I +D++T ++N G+L SRKGVN P + L A++ KD+
Sbjct: 109 LEVGEYVFFADGTIRTKVIEKDSDSVTLLVKNPGVLSSRKGVNFPHSNLRLSAITPKDEK 168
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
DL FG ++GVD++ SF+ + + + R IL ++ N
Sbjct: 169 DLRFGAKEGVDIVAISFVNSAQDIKKARSILAQEEAN 205
Score = 39.9 bits (89), Expect = 0.13
Identities = 19/49 (38%), Positives = 29/49 (59%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
I++K E + + N I+ SDG+MVARG LGI + ++ P + I K
Sbjct: 208 IVAKIETKKAVENLESILQASDGVMVARGDLGIEVGIEKVPVIQKRIIK 256
>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
araneosa HTCC2155
Length = 485
Score = 120 bits (288), Expect = 1e-25
Identities = 73/218 (33%), Positives = 116/218 (53%), Gaps = 2/218 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GP ++ L +E G++V R+NFSHGSHE HAE I+ A +G
Sbjct: 10 VSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG---- 63
Query: 476 LAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 652
I D +GP+IR G ++EGG ++L+ G+ + +TT E T++ + +
Sbjct: 64 --ILGDLQGPKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTVF---QALPR 114
Query: 653 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 832
VK G+ I +DDGL+ + + + + + C + G L S KG+NLP + PA++EKD+
Sbjct: 115 EVKVGDPILMDDGLLEAVVERIEGNEIFCKMLVAGKLTSNKGINLPETDIQSPALTEKDE 174
Query: 833 SDLLFGVE-QGVDMIFASFIRNGAXLHEIRGILGEKGK 943
DL F +E +D + SF+R G L I + + GK
Sbjct: 175 RDLKFIIENDAIDFVALSFVRKGEDLDIIHAAMDKIGK 212
Score = 50.0 bits (114), Expect = 1e-04
Identities = 25/56 (44%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G+ +ISK E +V+ + II +SD +MVARG LG+ IP ++ P K MI KC
Sbjct: 211 GKRKPVISKIEKPSALVDIDAIIEKSDALMVARGDLGVEIPSEKVPVAQKTMIRKC 266
>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma mobile
Length = 483
Score = 118 bits (284), Expect = 3e-25
Identities = 78/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +2
Query: 287 SGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 466
S I T GP+S+N +L M GM R NFSHG H AE + A K + +L
Sbjct: 17 SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGDH---AEQLNKFVLA-KEVAKELNL 72
Query: 467 PFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNI 646
P SL LDTKGPEIR G ++ G S ++E+ K T+ LT Y+ T + +
Sbjct: 73 PMSLM--LDTKGPEIRVGKMKDG-SQKIEVGKIITV-LTDEVSYKTFEGIPTKFTVSHRM 128
Query: 647 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 826
VK G+ I DDG ++ I V + + N +L S K +N+PG + L +S+K
Sbjct: 129 DKDVKVGSYILFDDGKLTTIVTGVKSGIVEVKTINSHVLKSNKRINIPGAQLSLEFLSKK 188
Query: 827 DKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE-KGKNIR 952
DK D++FG++ V+ I ASF+ + + ++R +L + G++I+
Sbjct: 189 DKEDIIFGIKNDVNYIAASFVNSKQDVLDLRKLLKDNNGEHIQ 231
Score = 51.6 bits (118), Expect = 4e-05
Identities = 29/56 (51%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
GE QIISK E+ G+ N + II SDGIM+ARG LG+ IP P K +I KC
Sbjct: 227 GEHIQIISKIESVFGIENIDEIIEASDGIMIARGDLGLEIPYFEVPFYEKQIIRKC 282
>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
Length = 507
Score = 117 bits (281), Expect = 7e-25
Identities = 69/226 (30%), Positives = 111/226 (49%)
Frame = +2
Query: 260 DSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAE 439
++K R + + T GPAS + + + G +V R+NFSHGSHE H + R E
Sbjct: 13 NTKMRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE 72
Query: 440 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 619
A+ G P + I D +GP++R G G V LK G+ L G+
Sbjct: 73 ----AETGRP--IGILADMQGPKLRIGTFADG---RVVLKNGDRFVLDRDPT---PGDVT 120
Query: 620 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIP 799
+++ + + PG + +DDG I + ++ + + +GG L RKGVN+P
Sbjct: 121 RVHLPHPELYAATAPGQSLLLDDGKIRLAVEAADPTAIVTRVVDGGPLSDRKGVNVPDAV 180
Query: 800 VDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
+ +PA++EKD DL F + GVD I SF++ + R I+G++
Sbjct: 181 IPIPALTEKDLRDLDFALSLGVDWIALSFVQRAEDVIAAREIIGDR 226
Score = 40.7 bits (91), Expect = 0.074
Identities = 18/54 (33%), Positives = 31/54 (57%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G+ ++SK E +++ I+ SD +MVARG LG+ +P +R P + I +
Sbjct: 224 GDRAGLLSKIEKPAALLHLEDIVQASDALMVARGDLGVELPPERVPGVQKRILR 277
>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
8797
Length = 489
Score = 115 bits (277), Expect = 2e-24
Identities = 65/210 (30%), Positives = 117/210 (55%), Gaps = 2/210 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPAS + +L + G+++ R+NF+HG HE+ +E ++N E SA++ P
Sbjct: 18 IATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHEI----SAEMEKP-- 71
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ I D GP+IR G+L G E+ ++ + D N + Y+++
Sbjct: 72 IGILGDLSGPKIRLGVLPGD---EITCRQDMRFRFIQGLD---SDNPQELTCTYESLIGD 125
Query: 656 VKPGNRIFIDDGLISIICQSVSADT--LTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 829
++ G+ + + DG++++ SAD + C +E G++ S++GVNLPG+ + P ++EKD
Sbjct: 126 LRVGDPVLLADGMVAMRVVEKSADDEFVECVVEREGIIRSKQGVNLPGVQLSTPCLTEKD 185
Query: 830 KSDLLFGVEQGVDMIFASFIRNGAXLHEIR 919
SDL + VE G+D I SF+R+ + +++
Sbjct: 186 LSDLAWAVEHGLDYIGLSFVRSADDIRQLK 215
>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
Pyruvate kinase - Magnetococcus sp. (strain MC-1)
Length = 483
Score = 114 bits (275), Expect = 4e-24
Identities = 68/217 (31%), Positives = 115/217 (52%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
IR + I T GP + + + G++ R+NFSHGSHE H R E+ +
Sbjct: 4 IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
LG P L I +D +GP++R G E ++EVEL +G+ L + G+ + + + +
Sbjct: 60 LGRP--LGIMMDLQGPKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPH 111
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+ V++PG + ++DG I++ V + C + GG+L RKG+N+P + + A+
Sbjct: 112 NELFQVMRPGLELLLNDGRINLRVMEVEDFGVCCEVRVGGILSDRKGLNVPAAMLPVKAL 171
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
++KD DL FG+E G+D SF++ L E R ++
Sbjct: 172 TDKDLEDLEFGLELGIDWCALSFVQRPEDLREARKLI 208
Score = 38.3 bits (85), Expect = 0.39
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
+++K E Q + N I+ +DG+MVARG LG+ +R P K +I C
Sbjct: 214 LLAKIEKPQAVDNLEEIVKVADGVMVARGDLGVEYTPERVPAVQKRLIRMC 264
>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
Proteobacteria|Rep: Pyruvate kinase family -
Nitrosomonas europaea
Length = 496
Score = 114 bits (274), Expect = 5e-24
Identities = 66/219 (30%), Positives = 109/219 (49%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GPAS N VL +E G++V R+NFSHG+ + H ++ R +S
Sbjct: 2 MRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASVELVRSLARSLGRT 61
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
+G + D +GP+IR G E G ++ LK G+ L + GN + + +DY
Sbjct: 62 VG------VLADLQGPKIRIGKFEQG---KIRLKTGDEFILDAEC---QLGNQERVGLDY 109
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+ + N V+ G + +DDG I + V + C + GG+L + KG+N G + PA+
Sbjct: 110 RELPNDVEAGATLLLDDGRIVLTVAKVRESEIFCEVLQGGILSNNKGINRKGGGLSAPAL 169
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE 934
+ KD D+ D + SF R+G + R ++ E
Sbjct: 170 TAKDLLDIKTSAVIRADYLAVSFPRSGDDIRRARALMQE 208
>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
Length = 477
Score = 113 bits (273), Expect = 7e-24
Identities = 64/200 (32%), Positives = 109/200 (54%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPAS+ V L +E GMN+AR+NF+HGS E H + N R+A K
Sbjct: 12 VCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------D 65
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ I D GP+IR G ++ +E+KKG+ + L+ EK I +++K+ +
Sbjct: 66 VTIMGDLPGPKIRIGDIK-----PMEIKKGDILILS------EKPQEGVIPINFKDFSKY 114
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
VK G+ I+++DG + ++ + V D + + G + S KGVNLP + + + A+ + +K
Sbjct: 115 VKVGDSIYMNDGFVELMVEKVEDDKVYAVSLSAGKISSHKGVNLPNVDLPVRAIGDYEKR 174
Query: 836 DLLFGVEQGVDMIFASFIRN 895
+ F + +D I SF+++
Sbjct: 175 CIDFAKKIDMDAISVSFVKD 194
Score = 39.9 bits (89), Expect = 0.13
Identities = 20/36 (55%), Positives = 24/36 (66%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIP 1059
II+K E Q + N + I+ SDGIMVARG LGI P
Sbjct: 214 IIAKIERPQALKNIDEILEASDGIMVARGDLGIETP 249
>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
organisms|Rep: Pyruvate kinase - Phaeodactylum
tricornutum
Length = 665
Score = 113 bits (271), Expect = 1e-23
Identities = 66/214 (30%), Positives = 111/214 (51%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GPAS N ++ G +V R+NFSHGS E E + RE E+ YS +G
Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
I D +GP++R G +EL G++ +L + KG+ + + + I
Sbjct: 214 --ILGDLQGPKLRVGEFSKPEGEFLEL--GQSFRLDLDN---AKGDNKRVQLPHPEIIKA 266
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ G+ + +DDG + ++ + D L C ++ GM+ RKGVN P +++ ++ KD+S
Sbjct: 267 SELGHALLVDDGKVKLVVTAKGDDYLECRVDVAGMIKDRKGVNTPDSVLEISPLTPKDRS 326
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
DL + + GVD + SF++ A + EI ++ EK
Sbjct: 327 DLEYMLGIGVDWVALSFVQTPADMVEIHALIDEK 360
>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
pseudomallei)
Length = 484
Score = 112 bits (270), Expect = 2e-23
Identities = 63/219 (28%), Positives = 113/219 (51%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GP+S + G +V R+NFSHG+H HA +R+ A ++ A++
Sbjct: 13 RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G P + + LD +GP++R G G ++ KG G+A + + +
Sbjct: 69 GHP--IGVLLDLQGPKLRVGQFASG---RAQIAKGRPFVFDRDP---APGDARRVSLPHP 120
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
I + +PG+ + +DDG + +VS+ + T G++ RKGV++P + +PA+S
Sbjct: 121 EIFDAARPGHLLLVDDGKLRFRVDAVSSARIETTALLDGIVSDRKGVSVPDATLAIPALS 180
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
KD+ DL FG+ GVD + SF++ + + R ++G +
Sbjct: 181 AKDRDDLEFGLSLGVDWVALSFVQTAQDVRDARALIGAR 219
Score = 35.9 bits (79), Expect = 2.1
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G I++K E Q + N I+ +D +MVARG LG+ + + P + I +
Sbjct: 217 GARAAIVAKIEKPQAVANIAEIVDAADAVMVARGDLGVEMSLEDVPSVQKQIIR 270
>UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 461
Score = 112 bits (269), Expect = 2e-23
Identities = 51/78 (65%), Positives = 62/78 (79%)
Frame = +2
Query: 719 SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNG 898
SAD L C I NGGMLGSRKGVNLP VDLPA+SEKDK DL FG+E GV+M+FASFIR
Sbjct: 117 SADYLDCKIINGGMLGSRKGVNLPNAEVDLPALSEKDKGDLRFGLEHGVEMVFASFIRKA 176
Query: 899 AXLHEIRGILGEKGKNIR 952
+H++R +LGE+G +I+
Sbjct: 177 TDVHQVREVLGEQGAHIK 194
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/57 (47%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK EN +G+ + I+ SDGIMVARG LGI IP ++ + K MI++C
Sbjct: 189 QGAHIKIISKIENQEGVAKFDEILEASDGIMVARGDLGIEIPPEKVFLAQKMMISRC 245
>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
lactis subsp. lactis (Streptococcus lactis)
Length = 502
Score = 108 bits (260), Expect = 2e-22
Identities = 70/214 (32%), Positives = 108/214 (50%), Gaps = 5/214 (2%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
+++N+A L +E G NV R NFSHG H + AE+ K+G LD
Sbjct: 38 SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88
Query: 494 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNITNVVKPGN 670
TKGPE+RT L G A + + G+ ++ T + + V +I + V+ G
Sbjct: 89 TKGPEMRTELFADGADA-ISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQ 147
Query: 671 RIFIDDGLISIICQSVSADTLTCTIE--NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL 844
I IDDG + + A T +E N G++G +KGVN+P + PA++E+D +D+
Sbjct: 148 TILIDDGKLGLSLTGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIR 207
Query: 845 FGVEQ--GVDMIFASFIRNGAXLHEIRGILGEKG 940
FG+ Q G++ I SF+R + E+R I E G
Sbjct: 208 FGLSQPGGINFIAISFVRTANDVKEVRRICEETG 241
Score = 49.6 bits (113), Expect = 2e-04
Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
Frame = +1
Query: 937 GEEH-QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMI 1092
G H Q+++K EN QG+ N + II +DGIM+ARG +GI +P + P + +I
Sbjct: 241 GNPHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLI 293
>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
Pyruvate kinase - Methylobacterium extorquens
(Protomonas extorquens)
Length = 483
Score = 107 bits (258), Expect = 4e-22
Identities = 66/215 (30%), Positives = 109/215 (50%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPAS ++ G +V R+N SH + E E I R E+ +
Sbjct: 10 RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G I +D +GP++R G G + L+ G+T L SD G+ D +++ +
Sbjct: 70 G------ILVDLQGPKLRLGTFVGDAAV---LENGQTFVL--DSD-PTPGDTDRVFLPHP 117
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
I + ++P + I IDDG + +I VS +E GG + +RKGV+LP + +PA++
Sbjct: 118 EILSALEPSHGILIDDGKLRLIVTEVSEGRAVTRVEVGGRISNRKGVSLPHTALPVPAMT 177
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGI 925
EKD+ DL G+ G D I SF++ + E++ +
Sbjct: 178 EKDRGDLEAGLAAGADWIAVSFVQRPEDVAEVKKV 212
Score = 41.1 bits (92), Expect = 0.056
Identities = 19/49 (38%), Positives = 30/49 (61%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
+++K E Q + + II SDGIMVARG LG+ +P ++ P + I +
Sbjct: 219 VMAKIEKPQALTRLDEIIEISDGIMVARGDLGVEMPLEQVPGVQKRITR 267
>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
pernix|Rep: Pyruvate kinase - Aeropyrum pernix
Length = 458
Score = 107 bits (258), Expect = 4e-22
Identities = 65/215 (30%), Positives = 113/215 (52%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GP+S + ++L + G++VAR+N SHG E + + R AE++ ++G
Sbjct: 8 VATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG---- 63
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+A+D +GP +RTG S V+L+KG+ + L + E + VD +
Sbjct: 64 --VAVDLEGPRVRTG-----NSEPVKLEKGDLVTL----GFME----GDVPVDARQFFET 108
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ G+ + +DDG I + +SV + + GG+LG RKGV + G DLP +S KD+
Sbjct: 109 IDEGDIVLLDDGKIILQVESVEGFRVKARVLEGGVLGPRKGVVVRGKEPDLPPLSAKDRR 168
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
L F ++GV ++ SF R+ + ++R ++ G
Sbjct: 169 ALEFFADKGVSHVYVSFARSAEHVEKVRTVVRRLG 203
>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
Length = 498
Score = 107 bits (256), Expect = 7e-22
Identities = 70/215 (32%), Positives = 108/215 (50%), Gaps = 6/215 (2%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
A +N+A L + G+NV R NFSHG +E + RE K + + LD
Sbjct: 39 AKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGVNIST------MLD 89
Query: 494 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV----DYKNITNVVK 661
TKGPEIR + EVE+K +++ T+ +E G ++ V N+ V+
Sbjct: 90 TKGPEIR---VYKTSEKEVEIKSDSKVRIYTTK--KEIGTSEKFSVLDSTGTYNMAKDVQ 144
Query: 662 PGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
PGN IF+DDG + +I +V + N +L K +NLP +P +S+KD++
Sbjct: 145 PGNTIFVDDGKLKLEVISSNVEEGIIETIARNTWILRENKRINLPDSNYSIPFMSDKDRN 204
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
D++F ++ D I ASF+ G + EI+ IL E G
Sbjct: 205 DIIFAIKNKFDYIAASFVNTGDNVREIKKILKEHG 239
Score = 47.6 bits (108), Expect = 6e-04
Identities = 26/54 (48%), Positives = 32/54 (59%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
GE QIISK E G+ + + II ESD IMVARG LG+ +P P + I K
Sbjct: 240 GEHIQIISKIETMTGIKSLDDIIDESDSIMVARGDLGLEVPYYDVPTYEKYIIK 293
>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 474
Score = 105 bits (251), Expect = 3e-21
Identities = 68/212 (32%), Positives = 114/212 (53%), Gaps = 1/212 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GP SR+ + E G++V R+NFSHG H H E ++ R AE A +G P
Sbjct: 14 VATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP-- 67
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
LA D +GP++R G +GG S ++ +K I + ++ + +TI V + I +
Sbjct: 68 LATLADLQGPKVRVGKFDGG-SLKLGFRKEYRIIVGETAP-----DPETIPVPHAEIVAI 121
Query: 656 VKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 832
++ G+ I DDG LI + S + + G LG +KG + G + + A++EKD+
Sbjct: 122 LEEGDTILADDGKLIFTVISGGSEPRVRAEVP--GKLGDKKGFTVRGKALPVRALTEKDR 179
Query: 833 SDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
+DL F +E GVD++ SF++ + E++ I+
Sbjct: 180 ADLDFALEIGVDIVALSFVQTVEDVEEVKAII 211
>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
Pyruvate kinase - Chromobacterium violaceum
Length = 468
Score = 104 bits (249), Expect = 5e-21
Identities = 59/220 (26%), Positives = 108/220 (49%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GP+S + G+N+ R+N SHGSH+ H + R AEK+
Sbjct: 2 LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDRP 61
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
+G + +D +GP++R G +K G+ + + +GNA+ + +
Sbjct: 62 IG------VLVDLQGPKLRIGKFP----QPTTVKTGDRYEFVLD---ETEGNAERATLPH 108
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
++PG+ I ++DG ++ + + + GG L S KG NLP + L A+
Sbjct: 109 PEAFEALEPGHLILVNDGKLAFEVAEMHPRRIVTRVTVGGELSSNKGFNLPHTVLPLSAI 168
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
+ KD+ D F +E+G D + SF++ A + +R I+G++
Sbjct: 169 TGKDRKDAEFALEEGADWVAMSFVQTAADVKALRDIVGKR 208
Score = 34.3 bits (75), Expect = 6.4
Identities = 17/52 (32%), Positives = 28/52 (53%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMI 1092
G+ I++K E + + I +DG+MVARG LG+ +P + P + I
Sbjct: 206 GKRVGIVAKIEKPSAVDDLEAIAELADGVMVARGDLGVELPPEDVPVVQRRI 257
>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
(Lyme disease spirochete)
Length = 477
Score = 103 bits (247), Expect = 9e-21
Identities = 62/197 (31%), Positives = 102/197 (51%)
Frame = +2
Query: 350 EXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLE 529
+ G+NV R+N +H SHE + I N R+ +A+ +DTKGPE+RT +E
Sbjct: 27 DAGVNVIRLNTAHQSHEDTIKVIDNVRKISNK----------IALMIDTKGPEVRTANIE 76
Query: 530 GGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIIC 709
+ +K G+ + ++TS E N T +Y V G+++ IDDG + +
Sbjct: 77 N----PIIVKTGDKVIISTSP-INEPNNFQT---NYDGFVKEVPQGSKVLIDDGELEMTV 128
Query: 710 QSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFI 889
+ D L C I+N G + ++K +N PGI + L +V+EKDK + + VD I SF+
Sbjct: 129 VAKLPDRLICEIKNDGQIKNKKSINTPGISLKLQSVTEKDKGFIELAAKYNVDFIAHSFV 188
Query: 890 RNGAXLHEIRGILGEKG 940
R+ + +++ IL G
Sbjct: 189 RHSKDVQDVQEILTASG 205
Score = 42.3 bits (95), Expect = 0.024
Identities = 21/42 (50%), Positives = 27/42 (64%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
+IISK EN +G+ N I S GIMVARG +G+ IP + P
Sbjct: 210 KIISKIENQEGIDNIEEIAKASYGIMVARGDMGVEIPAEDVP 251
>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7070-PB, isoform B - Tribolium castaneum
Length = 535
Score = 102 bits (244), Expect = 2e-20
Identities = 59/200 (29%), Positives = 98/200 (49%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H L S+ RL+ P ++ + ++ GM VA + + + + E
Sbjct: 44 LEHLARLQEKSRVRRKRLT-QFSVIIPPRISIEHIEEFLKAGMTVALIRMDYFTVDEIEE 102
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
+ R + K+G + +AI LD EI+TG L E+EL+KG+T K+
Sbjct: 103 MVAMIRNVVDDFGKKIGRVYPIAIGLDVSEQEIKTGKLLKP-LKEIELEKGQTTKIVAKP 161
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
++ + + + IYV+Y+NI +VVKPG+ + I D I + V+ D + C IE G+L
Sbjct: 162 EFANRVSKEFIYVNYENIADVVKPGDSLIIGDDNIRMSAIEVARDIINCIIEKAGLLTDN 221
Query: 773 KGVNLPGIPVDLPAVSEKDK 832
V LP +P+ LP +K
Sbjct: 222 LSVKLPNVPITLPKTESHEK 241
>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 475
Score = 101 bits (242), Expect = 4e-20
Identities = 59/178 (33%), Positives = 98/178 (55%), Gaps = 1/178 (0%)
Frame = +2
Query: 383 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 562
SHG H H +TI +E + K+ +AI LDTKGPE+R+G + + LK+
Sbjct: 2 SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDVP----KPIMLKE 52
Query: 563 GETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 742
G+ T + +T+ V+Y + N V+ G+ + +D G++S++ +S S D + C
Sbjct: 53 GQEFNFTIKRGVSSE---NTVSVNYDDFVNDVEVGDILLVDGGMMSLVVKSKSKDLVKCQ 109
Query: 743 IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASF-IRNGAXLHE 913
+ +GG L SR+ +N+ G LP++++KD D+ FGV+ VD SF +N +HE
Sbjct: 110 VIDGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFWEKNYHMMHE 167
>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
Length = 553
Score = 101 bits (242), Expect = 4e-20
Identities = 63/228 (27%), Positives = 113/228 (49%), Gaps = 2/228 (0%)
Frame = +2
Query: 257 IDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREA 436
+D + CT GP+S NV V+ + G ++ R+NFSHG+ + H + ++A
Sbjct: 30 VDKNHPHFNRVKICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA 89
Query: 437 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA 616
+ K ++AI D +GP++R + +ELK+G+ L ++ G+
Sbjct: 90 -MQLTGK-----TVAIMGDIQGPKLRIAGFSNPDNC-IELKEGQEFTLDHNN---VNGDE 139
Query: 617 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLP 790
+Y+ +K V +P + I ++DG I ++ SV A + ++ GG LG+RKG+ +P
Sbjct: 140 SRVYLPHKEFFAVCEPNDDIILNDGYIRLVATSVDRQAMRIVTRVKTGGKLGARKGITIP 199
Query: 791 GIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE 934
+ L +S KD D+ G+D I SF++ A + E R + +
Sbjct: 200 TRILPLSGLSPKDLGDIRNACRLGMDWIALSFVQTKADVIEARDYIAK 247
>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
Proteobacteria|Rep: Pyruvate kinase II - Salmonella
typhimurium
Length = 480
Score = 101 bits (241), Expect = 5e-20
Identities = 73/224 (32%), Positives = 109/224 (48%)
Frame = +2
Query: 269 SSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSY 448
S +R + + T GPA+ L + G NV RMNFSHGS E H RE
Sbjct: 2 SRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREI---- 57
Query: 449 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 628
+AKLG +AI D +GP+IR + G +V L G+ L + E G+ + +
Sbjct: 58 AAKLGR--HVAILGDLQGPKIRVSTFKEG---KVFLNIGDKFLLDANLGKGE-GDKEKVG 111
Query: 629 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 808
+DYK + V PG+ + +DDG + + V + + GG L + KG+N G +
Sbjct: 112 IDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSA 171
Query: 809 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
A++EKDK+D+ GVD + SF R G L+ R + + G
Sbjct: 172 EALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARRLARDAG 215
>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
pneumophila|Rep: Pyruvate kinase II - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 474
Score = 100 bits (240), Expect = 7e-20
Identities = 63/224 (28%), Positives = 112/224 (50%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GPAS+ +L + G+NV R+NFSH + I R+ + +
Sbjct: 2 LRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSSA-LQLIALVRKI----ADE 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
L P +A+ D +GP+IR G + + + L G+ L + G+ + + V Y
Sbjct: 57 LNHP--VAVMADLQGPKIRVGRFQ---NKSITLIDGQNFTLDCMAP-DTLGDINGVSVAY 110
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
N+ N + G+ + I+DGLI + +S + C + GG+L KG+N G + +
Sbjct: 111 PNLANELSIGDHLLINDGLIELEVIEISGSKIHCKVVEGGVLTDLKGLNRKGGGLAARTL 170
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
+EKD++DL +E VD I SF+++ + + R ++ + G I
Sbjct: 171 TEKDRNDLRTAIEAEVDYISLSFVKDAEDIRQARALMKDYGAQI 214
Score = 34.7 bits (76), Expect = 4.8
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
II+K E + + + II E+D IMVARG LG+ + P
Sbjct: 217 IIAKIERMEALDHLTDIIREADAIMVARGDLGVEVGAAEVP 257
>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 471
Score = 100 bits (240), Expect = 7e-20
Identities = 66/221 (29%), Positives = 111/221 (50%), Gaps = 3/221 (1%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPAS + L ++ G+++ R+NFSHG E I RE E +
Sbjct: 6 IATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------IP 59
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV--DYKNIT 649
+ I D GP+IR G L G + + KG+ + L ++K D Y+ D+K I
Sbjct: 60 ITIMQDLSGPKIRIGALPG--DVALNVSKGDVLCLGP----EDKRTNDYPYIPFDHKAIL 113
Query: 650 NVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 826
+ + + + + DG + + + S T + G++ SRKG+ LPG + +PA++EK
Sbjct: 114 SDLVVNDILILADGTLQFQVKEQNSNGTFLLIAQEDGIITSRKGLALPGKSIKVPAITEK 173
Query: 827 DKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
D+ DL G++ GVD + SF+++ + E + I+ G +I
Sbjct: 174 DQKDLSDGLKLGVDAVAISFVQSAEDIIEAKRIIKANGYDI 214
Score = 35.5 bits (78), Expect = 2.8
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
G + +I+K E + + I+ E D IMVARG LGI P P K +I C
Sbjct: 211 GYDIPVIAKLERRNAIEHLEEILKEVDIIMVARGDLGIECPLPELPAIQKRIIRAC 266
>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma pneumoniae
Length = 508
Score = 100 bits (240), Expect = 7e-20
Identities = 64/200 (32%), Positives = 100/200 (50%), Gaps = 3/200 (1%)
Frame = +2
Query: 347 MEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLL 526
++ G+ V R+NFSHG+HE A I+ R+ K KL P S I LDT GPEIR +
Sbjct: 48 IKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPEIR--VF 99
Query: 527 EGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK-NITNVVKPGNRIFIDDGLISI 703
E LK E + TT+ + + N+ N VK G +I +DDG +S+
Sbjct: 100 ETAPEGLKILKDSEVVINTTTKEVAKNNQFSVSDASGTYNMVNDVKVGQKILVDDGKLSL 159
Query: 704 ICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIF 877
+ + + + + C +N + ++K +NLP +P +S KD D+ FG+ +D I
Sbjct: 160 VVKRIDTKNNQVICVAQNDHTIFTKKRLNLPNADYSIPFLSAKDLRDIDFGLTHQIDYIA 219
Query: 878 ASFIRNGAXLHEIRGILGEK 937
ASF+ + ++R L K
Sbjct: 220 ASFVNTTENIKQLRDYLASK 239
Score = 44.8 bits (101), Expect = 0.005
Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 934 KGEEH-QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
K +H ++I+K E++ + N + II SDGIMVARG LG+ IP + P + MI C
Sbjct: 239 KNAKHVKLIAKIESNHALNNIDGIIKASDGIMVARGDLGLEIPYYKVPYWQRYMIKAC 296
>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
isozyme A, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 593
Score = 100 bits (240), Expect = 7e-20
Identities = 74/246 (30%), Positives = 115/246 (46%), Gaps = 8/246 (3%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + ICT GPA+ L E GMNVAR+N HG+ E+H I R +
Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEE----- 168
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
F++AI +DT+G EI G L G SA+ E GE T S + T+ V+Y
Sbjct: 169 -KGFAVAIMMDTEGSEIHMGDLGGASSAKAE--DGEIWNFTVRS-FDPPLPERTVTVNYD 224
Query: 641 NITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD-- 805
VK G+ + +D G++ + + + D + C + G+L R + G V
Sbjct: 225 GFAEDVKVGDELLVDGGMVRFEVIEKIGPD-VKCLCTDPGLLLPRANLTFWRDGKLVRER 283
Query: 806 ---LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIRSSPRXKIT 976
LP +S KD D+ FG+ +GVD I SF+++ + ++ + + ++ S KI
Sbjct: 284 NAMLPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIE 343
Query: 977 REWSIK 994
S+K
Sbjct: 344 SIDSLK 349
Score = 39.9 bits (89), Expect = 0.13
Identities = 20/49 (40%), Positives = 28/49 (57%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
+I+K E+ + N II SDG MVARG LG IP ++ P + I +
Sbjct: 338 VIAKIESIDSLKNLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQ 386
>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 496
Score = 100 bits (239), Expect = 9e-20
Identities = 67/227 (29%), Positives = 106/227 (46%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPAS A+L + G+NV R+NFSHG + H + R A +
Sbjct: 23 RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
+ +AI D +GP+IR G G V L G L S E G+ D + +DYK
Sbjct: 78 -AGHEVAIMADLQGPKIRVGKFAEG---RVLLAPGAPFVLDASRT--EPGDIDGVGLDYK 131
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
+ + VK G+ + ++DGLI + +V + + T++ GG L + KG+N G + A++
Sbjct: 132 ELPHDVKGGDLLLLNDGLIVLSVDAVRGEQVHTTVKIGGELSNNKGINKKGGGLTASALT 191
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIRSSP 961
KD D+ + D + SF +N + R + R P
Sbjct: 192 AKDMEDIRTAMGFQADYVAVSFPKNATDMEMARQLCTVAASEQRHKP 238
>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 478
Score = 99.5 bits (237), Expect = 2e-19
Identities = 58/222 (26%), Positives = 112/222 (50%), Gaps = 4/222 (1%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GP SR+ AV+ + G+ + R+NFSH A+ I++ RE E+
Sbjct: 6 IATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------I 59
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
L + D GP+IR G + G A + + G+ ++L + G+A + ++ I
Sbjct: 60 LTLMGDLSGPKIRIGEVAG---APLSVATGQLVRLGPARAKGAFGDALYLPLELAEILEQ 116
Query: 656 VKPGNRIFIDDGL----ISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 823
+KPG + + DG+ + + + +N G++ S KG++ PG+ +DLPA++
Sbjct: 117 LKPGAPVILSDGIPVFRVRKRLDTEAGPVFELETQNSGLVSSNKGISFPGLAIDLPALTA 176
Query: 824 KDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
KD+SD+ ++ G+D + SF++ + +++ + G+ +
Sbjct: 177 KDRSDVAAALDVGIDALALSFVQKSQDVVDLKKEMEHHGRQV 218
>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
fastidiosa
Length = 501
Score = 98.7 bits (235), Expect = 3e-19
Identities = 68/220 (30%), Positives = 100/220 (45%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPA+ VL + G+NV R+NFSHG A R A ++
Sbjct: 19 RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G I D GP+IR G G +V L L S+ G+A + V Y
Sbjct: 79 G------ILADLPGPKIRIGRFTEG---KVRLVADARFDLLADSN-APLGDATQVGVSYL 128
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
+ V G+ + +DDGL+ + V + T+ N G+L RKG+N G + L A++
Sbjct: 129 GLPQDVAAGDVLLLDDGLMQLQVVQVQGARIVTTVLNDGVLSDRKGLNKQGGGLSLGALT 188
Query: 821 EKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
++D+ + GVD I SF R+ +HE R I E G
Sbjct: 189 DRDRELIGIVSRMGVDFIAVSFCRHAEEMHEARRIARECG 228
Score = 37.9 bits (84), Expect = 0.52
Identities = 20/54 (37%), Positives = 30/54 (55%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G + ++SK E + +VN I+ SD +MVARG LG+ I + P + I K
Sbjct: 228 GCDAALVSKIERAEAIVNLAEIVAASDVVMVARGDLGVEIGDAQLPGLQKKIIK 281
>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
Babesia bovis|Rep: Pyruvate kinase family protein -
Babesia bovis
Length = 693
Score = 97.9 bits (233), Expect = 5e-19
Identities = 66/238 (27%), Positives = 115/238 (48%), Gaps = 17/238 (7%)
Frame = +2
Query: 266 KSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKS 445
+ ++ L+ + T GP++ L ME G ++ R+NFSHG+ + R R+ E
Sbjct: 105 QGQFMTLTKQVSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELV 164
Query: 446 YSAKLGSPFSLA----IALDTKGPEIRTGL-----------LEGGGSAEVELKKGETIKL 580
S+ GS + I D +GP++R G +E + VELKKG+
Sbjct: 165 RSSGEGSDSFMVSPKGILGDIQGPKLRIGRFMPNVDAVGKGIESSAAEFVELKKGDKFTF 224
Query: 581 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENG 754
T + KG+ + ++ +I + GN I +DDG +++ SV D ++T + N
Sbjct: 225 DT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNLEVISVDRDAPSVTAVVLND 281
Query: 755 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
G+L SRKG +P + + + SEKD D +F G+D + SF++ + ++ I+
Sbjct: 282 GVLSSRKGFAVPNVAITVDLFSEKDVKDTIFSYALGLDFLGVSFVQRMTDILYLKNII 339
Score = 34.7 bits (76), Expect = 4.8
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
II K E + + N I+ SDG+M+ARG LG+ P K +I C
Sbjct: 405 IIPKIEKQPALDDINGILEVSDGMMIARGDLGVETEITNLPVIQKRLIQLC 455
>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 527
Score = 95.9 bits (228), Expect = 2e-18
Identities = 69/237 (29%), Positives = 121/237 (51%), Gaps = 11/237 (4%)
Frame = +2
Query: 263 SKSSYI-RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAE 439
SKSS+ L+ + T GP SR+V L ++ GM+VAR +FS G +YH ET+ N + A
Sbjct: 21 SKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAV 80
Query: 440 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 619
+S + KL A+ LDT GPE++ + + LK + LT + D ++ +++
Sbjct: 81 RS-TKKL-----CAVMLDTVGPELQ---VINKSEKAITLKADGLVTLTPNQD--QEASSE 129
Query: 620 TIYVDYKNITNVVKPGNRIFIDDGLIS--------IICQSVSADTLTCTIENGGML-GSR 772
+ +++ + VK G+ IF+ L + + V D + C N L GS
Sbjct: 130 VLPINFNGLAKAVKKGDTIFVGQYLFTGSETTSVWLEVDEVKGDDVICLSRNAATLAGSL 189
Query: 773 KGVNLPGIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
++ + +DLP ++EKDK + +GV+ +D + S+ R+ + + R +L + G
Sbjct: 190 FTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQTREMLKKLG 246
Score = 42.7 bits (96), Expect = 0.018
Identities = 20/52 (38%), Positives = 35/52 (67%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
QI +K EN +G+ + + I+ E+DGI+++RG LGI +P ++ + K + KC
Sbjct: 252 QIFAKIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKC 303
>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 246
Score = 95.5 bits (227), Expect = 2e-18
Identities = 57/204 (27%), Positives = 99/204 (48%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + + T GPA+ + V+ + G++V R+N SH H+ E R+ ++ ++
Sbjct: 36 RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G + D +GP+IR G + S V L++ L + G+ + + + Y
Sbjct: 96 G------VLCDLQGPKIRIGRFK---SDFVMLEEDGAFILDAECPLTD-GDDERVGLTYP 145
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 820
++ N V G+ + +DDG I + V + C + GG L + KG+N G + PA++
Sbjct: 146 DLINDVARGDTLLLDDGAIVLWIAEVEGKQVHCKVVVGGKLSNNKGINKQGGGLSAPALT 205
Query: 821 EKDKSDLLFGVEQGVDMIFASFIR 892
EKDK D+ F E D + SF+R
Sbjct: 206 EKDKQDIKFAAEIDADYLAVSFVR 229
>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
Pyruvate kinase - Thermotoga maritima
Length = 466
Score = 95.5 bits (227), Expect = 2e-18
Identities = 61/224 (27%), Positives = 112/224 (50%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GP + + ++ ++ G+NV R+N SHG + I ++ + K
Sbjct: 1 MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
P +AI +D GP+IRTG LE VELK+G+ LTT + GN + V+
Sbjct: 57 KKKP--VAILIDLAGPKIRTGYLE---KEFVELKEGQIFTLTTK---EILGNEHIVSVNL 108
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
++ VK G+ I + DG I + + + ++ GG + R+GVN+P + + ++
Sbjct: 109 SSLPKDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPTADLSVESI 168
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNI 949
+++D+ + G V+ SF+R + + + + + GK I
Sbjct: 169 TDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHGKEI 212
Score = 46.0 bits (104), Expect = 0.002
Identities = 24/54 (44%), Positives = 31/54 (57%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G+E +ISK E + + II SDGIMVARG LG+ IP + P + I K
Sbjct: 209 GKEIPVISKIETKKALERLEEIIKVSDGIMVARGDLGVEIPIEEVPIVQKEIIK 262
>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
Length = 485
Score = 93.1 bits (221), Expect = 1e-17
Identities = 64/221 (28%), Positives = 108/221 (48%), Gaps = 2/221 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPAS++ ++ + G+N+ R+NFSHGS + H + C + + SA+LG
Sbjct: 7 IATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK--Y 60
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ + +D +GP+IR + VEL G+ L + G+ + + Y ++
Sbjct: 61 VGVLVDLQGPKIRIACFKND---VVELVAGQRFVLDAKLA-EFDGSVSAVGLGYPDLIAD 116
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIE--NGGMLGSRKGVNLPGIPVDLPAVSEKD 829
+ + + +DDG I + VS + L T + N G L +RKG+NL G + PA++ KD
Sbjct: 117 LNIDDVLLLDDGRIHLQVTEVSKEELKVTTKVLNSGKLSNRKGINLLGGGLSAPALTPKD 176
Query: 830 KSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
D+ D + SF RN +H R E G +++
Sbjct: 177 IEDMSTAALLNADFLAISFPRNAQDIHYARKKAKEAGCDVQ 217
>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
marina DSM 3645
Length = 490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 56/211 (26%), Positives = 106/211 (50%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GPA +L + G++V R+N +HG + H+ RE S +L P
Sbjct: 16 VATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIREI----SERLKRP-- 69
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+A D GP+IR G L VE + I+ +++ E + +Y+ + +
Sbjct: 70 VATLADLSGPKIRLGTLVQDPIYCVEEQMYRFIRGDVATEPNE------LVSNYEPLIDE 123
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
VK G+ + + DG I++ + D++TC + GG+L SR+G+NLPG + + ++ +D+
Sbjct: 124 VKVGDNVMLADGTITMEVVEKTEDSVTCVVVAGGILRSRQGINLPGTKLGVETITPRDRD 183
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
+ + E +D + SF+R + +++ +L
Sbjct: 184 HIRWAAETDLDYVSLSFVREADDIRQLKDLL 214
Score = 36.7 bits (81), Expect = 1.2
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
+I+K E + + N I+ S+G+MVARG LG+ I + +I K
Sbjct: 223 VIAKIEKREALDNLEEIVEVSNGVMVARGDLGVEIDVAEVAAAQKLIVK 271
>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
Length = 745
Score = 92.3 bits (219), Expect = 2e-17
Identities = 67/226 (29%), Positives = 105/226 (46%), Gaps = 13/226 (5%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPAS N L G++V R+NFSHG I + R EK Y +G
Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157
Query: 476 LAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
I D +GP+IR G + E + VELK+G+ + GN + + ++Y
Sbjct: 158 --ILGDIQGPKIRIGEFEKNQINENDNNTFVELKEGDLFSFDLMNSL---GNQNRVQLNY 212
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADT-------LTCTIENGGMLGSRKGVNLPGI 796
+ K G I +DDG + + + DT + + GG L S+KG +P +
Sbjct: 213 PELIKNAKAGQIILLDDGNLKMKILENNYDTSNIQNSYIKVQVLTGGKLYSKKGFCIPNM 272
Query: 797 PVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE 934
+ + +SEKD D+LF + + VD + SF++ L +R I+ +
Sbjct: 273 IMPIDVLSEKDIKDILFCINEEVDFLGYSFVQTEYDLIFLRNIIND 318
Score = 37.5 bits (83), Expect = 0.69
Identities = 23/51 (45%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
IISK E + N II SDGIM+ARG LGI P K +I C
Sbjct: 444 IISKIEKPSAIKNIENIIKLSDGIMIARGDLGIETNLSNLPILQKKLINLC 494
>UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate
kinase, liver and RBC, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to pyruvate kinase,
liver and RBC, partial - Ornithorhynchus anatinus
Length = 339
Score = 91.9 bits (218), Expect = 3e-17
Identities = 40/74 (54%), Positives = 56/74 (75%)
Frame = +2
Query: 731 LTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLH 910
L +E+GG LGSRKGVN+PG +DLPAVSE+D DL FG++Q VD++FASF+R A +
Sbjct: 55 LVTEVESGGRLGSRKGVNVPGAVLDLPAVSEQDARDLRFGLDQDVDIVFASFVRKAADVA 114
Query: 911 EIRGILGEKGKNIR 952
E+R LG +G+ ++
Sbjct: 115 EVRAALGPRGRAVK 128
>UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania
braziliensis|Rep: Pyruvate kinase - Leishmania
braziliensis
Length = 91
Score = 91.9 bits (218), Expect = 3e-17
Identities = 53/99 (53%), Positives = 67/99 (67%), Gaps = 1/99 (1%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXI-CTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEY 403
SQL H L I +R +G I CT GP++++V L ++ GM+VARMNFSHGSHEY
Sbjct: 2 SQLAHNLTLSIFEP---LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEY 58
Query: 404 HAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 520
H TI N R+A +A+LG ++AIALDTKGPEIRTG
Sbjct: 59 HQTTINNVRQA----AAELG--VNIAIALDTKGPEIRTG 91
>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
Pyruvate kinase - Theileria parva
Length = 699
Score = 90.6 bits (215), Expect = 7e-17
Identities = 69/238 (28%), Positives = 118/238 (49%), Gaps = 19/238 (7%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSH-EYH--AETIRNCR--EAEK 442
+ L+ + T GPA+ N + + G++V R+NFSH S H ++TIR E K
Sbjct: 116 LTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPPK 175
Query: 443 SYSAKLGSPFS-LAIALDTKGPEIRTG----------LLEGGGSAE-VELKKGETIKLTT 586
+Y +I D +GP++R G +L G E VELK G+ L T
Sbjct: 176 NYPFNGDHVVEHKSILGDIQGPKLRIGKFMPNLDVPGVLPGSKGCEFVELKAGD---LFT 232
Query: 587 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGM 760
Y G+ + +D+ I +K G++I +DDG +S+ + + ++T ++N
Sbjct: 233 FDAYDVLGSKSRVQLDFPEILKELKVGDKILLDDGNLSMTVVKTNPEEPSVTAEVKNDYK 292
Query: 761 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE 934
L SRKG ++P + + + + EKD D +F + GVD + SF++N + + + IL +
Sbjct: 293 LSSRKGFSVPKVVLPIEFLDEKDVKDAIFCLGIGVDFLGVSFVQNKSDILYLINILND 350
Score = 33.9 bits (74), Expect = 8.5
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
II K E + + + I+ SDG+MVARG LGI P K +I C
Sbjct: 414 IIPKIEKQAALDDIHEILKVSDGLMVARGDLGIETDLANLPIVQKRLIQLC 464
>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
eutropha (strain C71)
Length = 483
Score = 89.8 bits (213), Expect = 1e-16
Identities = 61/212 (28%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 472
ICT GPA+ VL + GM +VAR N SHG H HA I+ R+ A+ F
Sbjct: 20 ICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGRF 74
Query: 473 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 652
+A+ +D GP+ R G L G EL G + L +D D + V + +
Sbjct: 75 -IAVLMDLPGPKFRLGELSNGAR---ELHLGADVILALEAD-----PPDGLPVKHPALLQ 125
Query: 653 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 832
++ G +++ DG I + + A+ + C + G + S G+N+P + ++ D+
Sbjct: 126 ALRVGESVYLADGAIRLEVKIAGAERVVCQVLVSGTVTSGSGINVPESKRSVLIPTDDDR 185
Query: 833 SDLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
L+F +EQ + I SF+++ L +R +L
Sbjct: 186 RHLVFALEQQAEWIGVSFVQSADDLIRVRTLL 217
Score = 39.1 bits (87), Expect = 0.23
Identities = 18/52 (34%), Positives = 30/52 (57%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMI 1092
G++ +++K E Q +V+ + I+ SDG+MVARG LG+ P + I
Sbjct: 220 GQQPLLMAKIEKRQALVDLDAIMATSDGVMVARGDLGVETDLAEIPLVQKRI 271
>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_95, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 89.0 bits (211), Expect = 2e-16
Identities = 60/226 (26%), Positives = 111/226 (49%), Gaps = 6/226 (2%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPA + L GMNVAR+N H + E+H + IR + +
Sbjct: 87 MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEEKG-- 144
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
+ +++ +DT+G +I +++ G V+ + E+I L T+ + E T+ +Y
Sbjct: 145 ----YCVSVMIDTEGGQIH--VVDHGAPFSVKAEN-ESIWLFTTQKF-EGSRPFTVQANY 196
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD-- 805
+ + + G+ + ID G+ S + L C + G+L R ++ G V+
Sbjct: 197 EGFSEGITVGDEVVIDGGMASFEVIEKIGNDLRCKCTDPGLLLPRAKLSFWRDGKLVEKN 256
Query: 806 --LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
LP +S KD +D+ FG+ +GVD I SF+++ + +++ L K
Sbjct: 257 YELPTISTKDWADIEFGISEGVDFIAMSFVKDANAIKQLKSYLSNK 302
Score = 40.3 bits (90), Expect = 0.097
Identities = 18/41 (43%), Positives = 28/41 (68%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
+++K E+ + + + II SDGIMVARG LG+ IP ++ P
Sbjct: 309 VLAKIESLESLQHLEEIIEASDGIMVARGDLGVEIPLEQIP 349
>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
Pyruvate kinase - Thermoplasma acidophilum
Length = 544
Score = 85.4 bits (202), Expect = 3e-15
Identities = 56/215 (26%), Positives = 106/215 (49%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GPAS + ++ ++ G+++ R+N +H + + + +S + +G
Sbjct: 6 VATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG---- 57
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
I +D KGPE+RTG GG T+K+++ DY I ++ N+ +
Sbjct: 58 --IMIDLKGPELRTGEFAGG-----------TLKISSGKDYVM---GKDIVLNNMNVLSA 101
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V+ G+RI + DG +S +S D T N G+L R VN+PG ++L ++++D++
Sbjct: 102 VQVGDRILMSDGEVSFEVEST--DPFTIRALNDGVLRDRSRVNIPGRFIELGTITDRDRA 159
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
+ G+ GVD SF++ + +R + + G
Sbjct: 160 FIREGIADGVDFFALSFVQKSENVDSLRDFVIDSG 194
Score = 47.2 bits (107), Expect = 8e-04
Identities = 24/54 (44%), Positives = 30/54 (55%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G + IISK E G+ N I+ SDGIMVARG LG+ +P K + I K
Sbjct: 194 GGDQYIISKIETKSGLDNIEEIVKSSDGIMVARGDLGVELPLKEVVLAQKHIIK 247
>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
Length = 548
Score = 81.8 bits (193), Expect = 3e-14
Identities = 61/227 (26%), Positives = 110/227 (48%), Gaps = 7/227 (3%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + +CT GPA V L GM VAR+N HG +H +R R +
Sbjct: 62 LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEEEG-- 117
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
F +++ +DT+G ++ + GG+A V+ + G T S ++ + T++V++
Sbjct: 118 ----FCVSLMVDTEGSQLLVA--DHGGAASVKAEDGSEWLFT--SKRTDESHPFTMHVNF 169
Query: 638 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD- 805
+ + G+ + ID G+ + + + V D L C + G+L R ++ G V+
Sbjct: 170 DKFSEDILVGDELVIDGGMATFEVIEKVGND-LRCKCTDPGLLLPRAKLSFWRNGKLVER 228
Query: 806 ---LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
LP +S KD +D+ FG+ +GVD I SF+++ + ++ L K
Sbjct: 229 NFGLPTLSAKDWADIEFGIAEGVDCIALSFVKDANDIKYLKTYLSRK 275
Score = 43.6 bits (98), Expect = 0.010
Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
Frame = +1
Query: 934 KGEEH-QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP 1074
K EH +I +K E+ + + N II SDG+MVARG LG+ IP ++ P
Sbjct: 275 KSLEHIKIFAKVESLESLKNLKDIIEASDGVMVARGDLGVQIPLEQIP 322
>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
torridus
Length = 555
Score = 81.4 bits (192), Expect = 4e-14
Identities = 55/214 (25%), Positives = 106/214 (49%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GPAS ++ ++ G++ R+N +H + Y + + + KS +G
Sbjct: 7 IATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG---- 62
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+ +D KGPE+RTG + G S +++ K I Y + N D I ++Y NI++
Sbjct: 63 --LMVDLKGPELRTGKFKDG-SFKIDYNKKYKIS------YNKNDNPD-ILINY-NISDF 111
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ I + DG + SV+ D + T + G L VN+PG + L +++++D+
Sbjct: 112 IDDKTLIAMSDGKLRFSVDSVNGDIINVTSLDSGSLRDNSRVNVPGKLLRLGSLTDRDRM 171
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
+ G++ V+ SF+++ ++E++ L E+
Sbjct: 172 FIEEGIKNNVNFYALSFVQSRENINELQDYLFER 205
Score = 38.7 bits (86), Expect = 0.30
Identities = 20/39 (51%), Positives = 24/39 (61%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXK 1065
Q+ISK E G N + I SD IMVARG LG+ +P K
Sbjct: 210 QLISKIETKSGYDNIDEIARASDFIMVARGDLGVEMPLK 248
>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
marinus F1|Rep: Pyruvate kinase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 469
Score = 81.4 bits (192), Expect = 4e-14
Identities = 57/211 (27%), Positives = 103/211 (48%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GP+S VL ++ G++ R+NFSHG+ E ++ RE + Y ++
Sbjct: 7 ITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYEREI----- 61
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+I D GP++R G L E+K +T+KL E+ +TI V + + +
Sbjct: 62 -SIMGDLPGPQVRIGELP-----VQEIKAKQTVKLVYKDKVDEE---NTIPVPNRKVFEI 112
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
++ G+ + IDDG I + + + + N +L K + + G +DLP +SEKD
Sbjct: 113 LELGDIVLIDDGKIILRIIDIGGNEAEAIVLNDAVLYPHKTLVVFGKEIDLPVLSEKDVD 172
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGIL 928
+ + V + + + SF+R + + +R I+
Sbjct: 173 LVNYSVSRKLTYLAISFVRRSSDIVIVRDIV 203
>UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma
japonicum|Rep: Pyruvate kinase - Schistosoma japonicum
(Blood fluke)
Length = 168
Score = 80.6 bits (190), Expect = 7e-14
Identities = 43/136 (31%), Positives = 73/136 (53%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYH 406
S +QH ID ++R + +CT G + + ++ GMN+ R+N S G+ E +
Sbjct: 25 SLMQHISNQSIDHAPFFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKY 84
Query: 407 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 586
AE IR R E+SY +P S+ IALD P +RTGL+ A V ++ G+ + LT
Sbjct: 85 AEVIRRVRRLEESYDY---NP-SVGIALDLSAPPVRTGLINESVDAVVVIQTGQMVTLTI 140
Query: 587 SSDYQEKGNADTIYVD 634
+ +Y++ + I+++
Sbjct: 141 NDEYEKNTTSSIIWIN 156
>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 500
Score = 79.8 bits (188), Expect = 1e-13
Identities = 59/224 (26%), Positives = 105/224 (46%)
Frame = +2
Query: 269 SSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSY 448
S +R + I T GPAS N ++ + GM++AR+N SHGS +H ET++ R
Sbjct: 29 SCTMRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADEL 88
Query: 449 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 628
+ ++G I +D GP++R L+ S ++ G+TI + ++ + I+
Sbjct: 89 NREIG------ILVDIPGPKLRV-LIH---SPPRDVVPGDTIHIAAEHEHA----SGAIH 134
Query: 629 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 808
V + V PG+ + + DG +++ LT T+ +GG + GV +PG D+
Sbjct: 135 VHPPDCIPKVCPGDVVLVGDGAVTLQVLKPGPPMLT-TVISGGTIREGMGVVIPGRRPDV 193
Query: 809 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
P + + G D I SF+ + + + R +L +G
Sbjct: 194 PYAGARFIDYIRQGAALRPDYIALSFVGSAEDIRDARTLLTREG 237
Score = 35.9 bits (79), Expect = 2.1
Identities = 16/47 (34%), Positives = 28/47 (59%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMI 1092
+I+K E + + + II +D +MVARG LG+ +P + P + +I
Sbjct: 243 LIAKIECRRAVEGLDDIIRHADAVMVARGDLGVELPLEEVPYIQKLI 289
>UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca
wickerhamii|Rep: Pyruvate kinase - Prototheca
wickerhamii
Length = 259
Score = 79.4 bits (187), Expect = 2e-13
Identities = 52/147 (35%), Positives = 81/147 (55%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 460
R + +CT GP S + + GMNV R+N SHG H H + I RE Y+A L
Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154
Query: 461 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 640
G +LAI LDTKGPE+R+G L + ++L+KG+ I T + G + I V+Y
Sbjct: 155 GRR-NLAIMLDTKGPEVRSGDL----TQPLDLEKGDLITFTIVAG--ADGTNNRIGVNYD 207
Query: 641 NITNVVKPGNRIFIDDGLISIICQSVS 721
+ V+ G+ + +D G+++++ +S S
Sbjct: 208 GFIDDVEVGDMLLVDGGIMTMLVKSKS 234
>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 1010
Score = 79.4 bits (187), Expect = 2e-13
Identities = 40/95 (42%), Positives = 56/95 (58%)
Frame = +2
Query: 227 SQLQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYH 406
SQL + L + + + L+ ICT GP+S VL + GM V R++FS G+H+ H
Sbjct: 165 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCH 224
Query: 407 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 511
+ I+ R+A Y+ + G P SLAIALDTKGP I
Sbjct: 225 CQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 259
Score = 60.5 bits (140), Expect = 9e-08
Identities = 29/51 (56%), Positives = 36/51 (70%)
Frame = +2
Query: 779 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILG 931
+N G+ DL A++E+DK DL FG +Q VDMIFASFIR+ L EIR LG
Sbjct: 259 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALG 309
Score = 48.0 bits (109), Expect = 5e-04
Identities = 27/55 (49%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Frame = +1
Query: 943 EH-QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
EH +IISK E+ Q + N + II ESDGIMVA G +G I + P K+++AKC
Sbjct: 315 EHIKIISKIESQQALANIDEIIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKC 369
>UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate
kinase isozyme M2; n=4; Rattus norvegicus|Rep:
PREDICTED: similar to Pyruvate kinase isozyme M2 -
Rattus norvegicus
Length = 123
Score = 78.6 bits (185), Expect = 3e-13
Identities = 40/89 (44%), Positives = 56/89 (62%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C L+IDS +G ICT G ++V +L + GMNVA +NFSHG+HEYHAE
Sbjct: 27 LEHMCCLEIDSAPIMAHNTGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAE 83
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTK 499
TI+N +S+++ S+ +ALDTK
Sbjct: 84 TIKNVCATTESFASDPILYLSIVVALDTK 112
>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 466
Score = 77.4 bits (182), Expect = 7e-13
Identities = 58/215 (26%), Positives = 99/215 (46%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I + GP+S + V+ E G++ R+NF+HG E REAE+ K G P
Sbjct: 9 IASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP-- 62
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
LA+ D GP IR G ++ ++L G+ + + E G+ I + + + V
Sbjct: 63 LALIGDLVGPSIRLGRVKN----PIKLNAGDRAEFRCVEE-SEGGDTKIIPLPVRRVYEV 117
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
+ G+ I +DDG + + VS + + SRK + + G LP +S++D
Sbjct: 118 LDEGDLIVMDDGRVRLRVLEVSGYSAIVEALTPATITSRKAIAIRGKDPGLPTLSQRDVE 177
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
+ F ++ G D I S +R + +R I+ +G
Sbjct: 178 HVKFALDNGFDYIALSHVRTRDDVDALRLIVLREG 212
>UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1;
Plasmodium berghei|Rep: Putative uncharacterized protein
- Plasmodium berghei
Length = 158
Score = 77.0 bits (181), Expect = 9e-13
Identities = 46/122 (37%), Positives = 65/122 (53%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+CT GPA ++V L ++ GM++ R NFSHG+H+ H + N +A+ +
Sbjct: 42 VCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNCT 95
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
L + LD KGPEIRTGLL G+ E LK+G +KL +DY G+ I Y T
Sbjct: 96 LGMLLDNKGPEIRTGLL---GNKEAHLKEGSKLKLV--ADYSYLGDETCIACSYTKCTTK 150
Query: 656 VK 661
K
Sbjct: 151 CK 152
>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
Pyruvate kinase - Nosema bombycis
Length = 441
Score = 77.0 bits (181), Expect = 9e-13
Identities = 56/214 (26%), Positives = 106/214 (49%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T S + L ++ G+++ R+N SHG+ H +I N R+ K ++G
Sbjct: 9 IVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG--IV 62
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
I LDT+GPE+R + E +E+ LK+G+ I T S+ + ++ I++ + T
Sbjct: 63 PVICLDTRGPEVRIEIAE---RSEIPLKEGDKI---TFSNVR---TSNKIFLPIPDFTKF 113
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
++I++DD +++I S T N L + K +LPG+ + +DK
Sbjct: 114 PLK-SKIYLDDAMLAIEVLETSKCECTGRAMNSHRLKNNKKASLPGLVFEDNESEARDKK 172
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
D ++ +D++FASFI + + ++ ++G +
Sbjct: 173 DFEIILKHKIDVVFASFINSRKEVESLKKLIGSE 206
Score = 41.5 bits (93), Expect = 0.042
Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Frame = +1
Query: 940 EEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXI-PXKRYPXPKNMIAKC 1101
E+ I SK E +G+ N + II SDGIM+ARG LG+ + K + K + KC
Sbjct: 206 EDVLIFSKIETLRGVENIDEIIEVSDGIMIARGDLGVEMTASKMFSTQKKITIKC 260
>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
Hrk 5)
Length = 464
Score = 77.0 bits (181), Expect = 9e-13
Identities = 55/215 (25%), Positives = 95/215 (44%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GP+S + + + G+N R+NFSH + E + R E
Sbjct: 7 VATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLRP------- 59
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
L + D +GP IR G A +++ G+ + T SS +EK + V +
Sbjct: 60 LTLIADLQGPVIRLGEF-----APFQVRPGDRVTFTLSSKTEEKY---AVPVPNGVFFEI 111
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
V+ G+ + ++ G ++ + G + RK V + G + LP ++EKD
Sbjct: 112 VREGDEVLVEGGRLAFRIVDAGPEKAVGEALLEGEVKPRKTVTVRGKDIPLPTITEKDLR 171
Query: 836 DLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
D+ F V+ G D I SF+R+ + + +R IL + G
Sbjct: 172 DIEFSVKAGFDAIALSFVRSSSDVQRLRDILFDYG 206
>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
family protein - Tetrahymena thermophila SB210
Length = 495
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/178 (29%), Positives = 89/178 (50%), Gaps = 26/178 (14%)
Frame = +2
Query: 497 KGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNI------TNV 655
+GP+IRT LL+ +E+KKG+ +K+T + +K + Y D + I + +
Sbjct: 61 QGPDIRTSLLKD--KKPIEIKKGQKLKITFNRFLIQKVDEQPEYEGDEQGIGCSIALSKL 118
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD-- 829
V+ G + + D I V+ + EN G+L K V LPG+ +DLP +SE+
Sbjct: 119 VQVGQHVLLSDNTIYSHVVEVNESDIVVQFENEGILNEVKNVRLPGVKIDLPTISEEGIF 178
Query: 830 ----KSDLLF-------------GVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
K+D F G+E+GVD I SF+R+G + +R +L +G++I+
Sbjct: 179 IIQFKNDQQFQLILIDEDFIISQGLEKGVDFIAVSFVRSGEDIEYVRDLLSPRGEHIK 236
Score = 53.2 bits (122), Expect = 1e-05
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+GE +II+K EN +GM N I+ SDGIMVARG LG+ IP ++ + K MI +C
Sbjct: 231 RGEHIKIIAKIENIEGMENFEDILKSSDGIMVARGDLGMVIPAQKVFVAQKWMIDRC 287
>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_171, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 622
Score = 72.9 bits (171), Expect = 1e-11
Identities = 63/219 (28%), Positives = 104/219 (47%), Gaps = 10/219 (4%)
Frame = +2
Query: 317 SRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDT 496
+ N ++ ++ G + R+N +HG+ +E IR R + S L P I +D
Sbjct: 271 TENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQMLEKP--CRILMDL 324
Query: 497 KGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE----KGNADTIYVDYKN--ITNVV 658
GP++RTG ++ G V L+ G+ + ++ S ++ + D V + + + V
Sbjct: 325 AGPKLRTGNMKAG-PCFVRLRVGDLLIISLDSSIEQDELTQPTVDAYRVTCPSSFLFDSV 383
Query: 659 KPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNLPGIPVDLPAVSEK 826
KPG I DDG I + Q SA + +I + G LG+ K +N+P + ++ K
Sbjct: 384 KPGEPIAFDDGKIWGVIQGTSASEIIVSITHASPRGTKLGAEKSINIPESNIRFEGLTTK 443
Query: 827 DKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
D DL F V DM+ SFIR+ + +R L EK K
Sbjct: 444 DLMDLEF-VAAHADMVGISFIRDVRDIVVLRAEL-EKRK 480
>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
Length = 501
Score = 72.1 bits (169), Expect = 3e-11
Identities = 58/216 (26%), Positives = 95/216 (43%), Gaps = 7/216 (3%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
A + +L + GMN AR+N H S + N R AE+ + I +D
Sbjct: 154 AEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR------ACRILMD 207
Query: 494 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT---IYVDYKNITNVVKP 664
GP++RTG L + + L+KGE + L ++ D+ + I V+
Sbjct: 208 LGGPKLRTGPL----AEPLTLRKGEGLVLCRDAEEGRSACEDSPARVVCAVSGIYGGVQV 263
Query: 665 GNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGIPVDLPAVSEKDK 832
G + DDG I + + V+ D + I + G L + KG+N P + L +SE+D
Sbjct: 264 GEAVLFDDGKIESVVRGVAQDEIQLEITRADDKGSRLAADKGINFPESRLKLRGLSEQDL 323
Query: 833 SDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
L F V + D++ SF + ++ LGE+G
Sbjct: 324 EHLDF-VARRADIVGMSFANEPEDVFALQAALGERG 358
>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
parvum|Rep: Pyruvate kinase - Ureaplasma parvum
(Ureaplasma urealyticum biotype 1)
Length = 474
Score = 69.3 bits (162), Expect = 2e-10
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 5/196 (2%)
Frame = +2
Query: 356 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 535
G+N+ RMN SHG + H + ++ K+ I DTKGPEIR +
Sbjct: 48 GVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIKV------EILFDTKGPEIRVCEMSDN 101
Query: 536 GSAEVELKKGETI---KLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 706
+K E I K + E D N+ + VK +RI IDDG + +I
Sbjct: 102 NFI---IKNSEVIIHCKEKVLGSFNEFSVTDA--TGQYNMISDVKINHRILIDDGKLILI 156
Query: 707 CQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFA 880
+ + + + T +N L + K +NLP LP +S+KD D+ V+ + +
Sbjct: 157 VKKIDFLKNIIYTTAKNSYSLKTNKRLNLPDANYSLPFLSKKDIDDINLAVKLKIPYLAL 216
Query: 881 SFIRNGAXLHEIRGIL 928
SFI N ++E++ +L
Sbjct: 217 SFISNIKQINEVKQLL 232
Score = 43.6 bits (98), Expect = 0.010
Identities = 20/50 (40%), Positives = 31/50 (62%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
++I+K E + + N II +DGIMVARG LG+ +P + P +N I +
Sbjct: 240 KLIAKIETQEAIDNLEEIIKNTDGIMVARGDLGLEVPFYKIPIYQNKIVE 289
>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
Pyruvate kinase - Sulfolobus solfataricus
Length = 452
Score = 68.1 bits (159), Expect = 4e-10
Identities = 60/220 (27%), Positives = 110/220 (50%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GP+S + ++V R+NF+HG H R + ++Y+
Sbjct: 1 MRKTKIVATLGPSSEEKV---KELAEYVDVFRINFAHGDETSH----RKYFDLIRTYA-- 51
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
P S +I +D GP++R G L+ +E+KKG+ I + +K D I VD
Sbjct: 52 ---PES-SIIVDLPGPKLRLGELK----EPIEVKKGDKIV------FSQK---DGIPVDD 94
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+ + VK + I I DG I + +S + D + T+ GG+L SRKG+N+P + + +
Sbjct: 95 ELFYSAVKENSDILIADGTIRVRVKSKAKDRVEGTVIEGGILLSRKGINIPNVNLK-SGI 153
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEK 937
++ D L ++ G D I SF+ + + +++ +G++
Sbjct: 154 TDNDLKLLKRALDLGADYIGLSFVISENDVKKVKEFVGDE 193
Score = 44.0 bits (99), Expect = 0.008
Identities = 21/54 (38%), Positives = 31/54 (57%)
Frame = +1
Query: 937 GEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
G+E +I+K E + + N I+ ESDGIMVARG LG+ + P + I +
Sbjct: 191 GDEAWVIAKIEKSEALKNLTNIVNESDGIMVARGDLGVETGLENLPLIQRRIVR 244
>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
Clostridium beijerinckii NCIMB 8052
Length = 340
Score = 64.5 bits (150), Expect = 5e-09
Identities = 59/223 (26%), Positives = 97/223 (43%), Gaps = 6/223 (2%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GP ++ AVL +E G+N R NF HGS E E ++ ++ +
Sbjct: 4 IGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKS----------D 53
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE--KGNADTIYVDYKNIT 649
+ + LD G ++R + G ++ GE I Y E K + + I V NI
Sbjct: 54 IQVMLDLSGTKVR---VSGKFQYIFKVYNGEVIYFCGEDKYSEVVKNSKNKIKVIPLNIK 110
Query: 650 NVV---KPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
N + K +I I D ++ I V TI GG++ KG N+ + +
Sbjct: 111 NKILNEKDYKQIGIKDNTMTFDIVDKVDGLIKAITI-RGGVIRKWKGCNIKNLERKELPL 169
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
+E DK +++GV VD+I SF+ + +++ L + N
Sbjct: 170 NENDKDAIVWGVNNKVDIICQSFVEEKKDIDDVKLFLNNRKSN 212
>UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 659
Score = 64.1 bits (149), Expect = 7e-09
Identities = 50/182 (27%), Positives = 84/182 (46%), Gaps = 4/182 (2%)
Frame = +2
Query: 356 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG----L 523
G+ +N G+ + I REAE S S +LG P + ++ + TG
Sbjct: 175 GVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKELGFPVTSSVMVKISPRHQFTGGFSTQ 234
Query: 524 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 703
G VEL +G+ + LT Y ++ NAD IYV+ + + V P + I I + I +
Sbjct: 235 FRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQL 293
Query: 704 ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFAS 883
+ +S+ AD L + GGML + V P +S ++ DL F E G++++ +
Sbjct: 294 MVRSIHADHLKGCVARGGMLYAHMPVLFPA-RCRRFRISYEELEDLTFAREVGLNVVVSH 352
Query: 884 FI 889
+
Sbjct: 353 IV 354
>UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
ATCC BAA-548
Length = 357
Score = 63.3 bits (147), Expect = 1e-08
Identities = 31/96 (32%), Positives = 51/96 (53%)
Frame = +2
Query: 665 GNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL 844
G RI DDG + ++ S L C + G L + K VN+PG + +PA++ KD+ +
Sbjct: 2 GARIIFDDGAMELLVLGKSGGLLHCEAKRDGELKNHKSVNVPGAELKMPALTRKDRDFIE 61
Query: 845 FGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
+ V+ +D I SF+R+ + +R IL +IR
Sbjct: 62 YAVKNDLDFIAHSFVRSANDVLAVRSILDTGDSDIR 97
Score = 50.0 bits (114), Expect = 1e-04
Identities = 25/52 (48%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYP-XPKNMIAKC 1101
+II+K EN QG+ N + I+ +DG+MVARG LGI IP + P K +I C
Sbjct: 97 RIIAKIENRQGVDNLDEILKAADGVMVARGDLGIEIPLEEVPLIQKKLIRAC 148
>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 476
Score = 62.1 bits (144), Expect = 3e-08
Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 4/202 (1%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
A+ +L +E GMNVAR+N +H + + + R+AE + I LD
Sbjct: 130 AAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR------CKILLD 183
Query: 494 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNR 673
GP+IRTG + + ++ +G+ I LT + + + ++ G
Sbjct: 184 LAGPKIRTGPV-AMPPGKTKVYRGDRILLTAKVPEASADISCQVTCSLPEVLAHLQVGAT 242
Query: 674 IFIDDGLISIICQSVSADTLTCTIE----NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDL 841
++IDDG I + + ++ G L + KG+N P + + ++++KD DL
Sbjct: 243 VWIDDGKIGARVVRIEPAGVVLEVDKVAPQGKKLRAEKGLNFPDSQLQIRSLTDKDCQDL 302
Query: 842 LFGVEQGVDMIFASFIRNGAXL 907
F V + D++ SF++ A L
Sbjct: 303 DF-VVRHADLVGYSFVQQPADL 323
>UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 105
Score = 60.9 bits (141), Expect = 6e-08
Identities = 39/105 (37%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Frame = -1
Query: 948 MFFPFSPRXPRISCSXAPXRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFR 769
M P SP+ IS + + +AKI+ T TP S +SFS+ AG+ST +PG+LTP
Sbjct: 1 MSLPSSPKTFLISKTSLAVSIKEAKIMWTLFLTPNLISAISFSDKAGKSTSVPGKLTPLW 60
Query: 768 DPSIPPFSMVHVRV-SALTD*QMIEMRPSSMKIRFPGFTTFVMFL 637
+ +P +V S+ T+ + PSS + PG T VMFL
Sbjct: 61 EEILPALRDSTFKVCSSSTEMTSNDKTPSSTYMILPGAMTLVMFL 105
>UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep:
Pyruvate kinase - Methanococcus jannaschii
Length = 447
Score = 60.9 bits (141), Expect = 6e-08
Identities = 62/219 (28%), Positives = 97/219 (44%)
Frame = +2
Query: 278 IRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 457
+R + + T GP+ N + G+ R N SH + +Y E N EK+ AK
Sbjct: 5 MRKTKILVTLGPSLENKLDKAINLIDGV---RFNMSHATTDY-CEKFLNI--LEKNNIAK 58
Query: 458 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 637
+ +D KG +IR ++ LK GE K+ D + N DTI
Sbjct: 59 V---------MDLKGIKIRIKEVKLKNKI---LKMGE--KVVIGEDIKLNYNIDTI---- 100
Query: 638 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 817
+ G+ I I+DG I + D + +E GG + GVNLP ++LP +
Sbjct: 101 -------EEGHFILINDGKIKLRVVE-KTDKIIAVVEVGGEIKEGMGVNLPDTRIELPII 152
Query: 818 SEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGE 934
E D ++ F VE+ + I SF+RN + E++ I+ E
Sbjct: 153 DETDLKNIKFAVEKDFEYIALSFVRNKEDVKELKDIISE 191
Score = 48.0 bits (109), Expect = 5e-04
Identities = 21/50 (42%), Positives = 31/50 (62%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAK 1098
++ISK E +G+ N I ESDG+MVARG LG+ +P + P + I +
Sbjct: 197 EVISKIETKEGLKNIKEIARESDGVMVARGDLGVEVPIENIPIEQKNILR 246
>UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter
jejuni|Rep: Pyruvate kinase - Campylobacter jejuni
Length = 319
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/195 (24%), Positives = 89/195 (45%)
Frame = +2
Query: 365 VARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA 544
+ R+N +HG E TI N R+ + + I +D G +IRT G S
Sbjct: 27 IYRINGAHGDIESIKNTIINLRKQKAD----------IDILIDLPGNKIRTS----GISE 72
Query: 545 EVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSA 724
++++K + L +YK +VKPG ++ +D + I + V+
Sbjct: 73 AIQVEKDKDFSLKIDQ------------FNYKEFYKLVKPGMEVYANDSVFLFIVKEVND 120
Query: 725 DTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAX 904
+ T ++ G+L + KG+++ + ++P + EKDK + E + + ASF+R +
Sbjct: 121 KEIIFTSKSTGLLLNNKGMHVRNLHDNIPFLFEKDKELIKLCNEFDIAYVGASFVRKASD 180
Query: 905 LHEIRGILGEKGKNI 949
+ EI+ +L K I
Sbjct: 181 IQEIKQVLHSNTKII 195
>UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2;
Alphaproteobacteria|Rep: Pyruvate kinase - Stappia
aggregata IAM 12614
Length = 512
Score = 56.4 bits (130), Expect = 1e-06
Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 5/197 (2%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
A+ + A + + GMNVAR+N +H E + + R A A+L + I +D
Sbjct: 165 AADDPAFVRDLVRKGMNVARLNCAHDGPEAWEKMAAHVRTA-----AELEGR-DVRILMD 218
Query: 494 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGN-ADTIYVDYKNITNVVKPGN 670
GP+IRT + +L GE +L + A T V + N ++ G+
Sbjct: 219 IAGPKIRTETVVPQKKTP-KLTIGERFRLVVQETPDAHSDIAVTASVSLPQMVNRLREGD 277
Query: 671 RIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSD 838
R+ DD + + + VS + ++G + +KG+NLP + + ++ KDK+D
Sbjct: 278 RLLYDDSKLEGVVEEVSNGEAVIRVTRAKDSGVKIKPQKGINLPDTALGVSPLTAKDKTD 337
Query: 839 LLFGVEQGVDMIFASFI 889
L V DM+ SF+
Sbjct: 338 LK-TVTALADMVGYSFV 353
>UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida
albicans|Rep: Pyruvate kinase - Candida albicans (Yeast)
Length = 92
Score = 54.0 bits (124), Expect = 7e-06
Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Frame = +2
Query: 581 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-SADTLTCTIENGG 757
TT Y+ K + + +DYKNIT V+ PG I++DDG++S SV TL N G
Sbjct: 12 TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISVDDQQTLKVRSLNAG 71
Query: 758 MLGSRKGVN 784
M+ S K N
Sbjct: 72 MISSHKTAN 80
>UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter
sphaeroides|Rep: Pyruvate kinase - Rhodobacter
sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
DSM158)
Length = 508
Score = 53.6 bits (123), Expect = 1e-05
Identities = 49/197 (24%), Positives = 92/197 (46%), Gaps = 4/197 (2%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
A+ + A++ + G + R+N +H E A I + R++E+ KL I++D
Sbjct: 161 AASDPAIVRELVAAGADAFRINCAHDGPEAWAAMIGHIRKSERMTGRKL------PISMD 214
Query: 494 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNR 673
GP+ R + + GG L+ G+ +G + + + + + PG +
Sbjct: 215 LGGPKFR--VTKTGGPLPKRLQAGDRFAFVEKPSLAPEGRGWAM-LGHPALLAALAPGVQ 271
Query: 674 IFIDDG-LISIICQSVSADTLTCTI---ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDL 841
+ +DDG L + + Q+ L E G L +GVNLPG +D+ A++E+D + L
Sbjct: 272 VSVDDGKLWATVIQTGRGHALLEVDRVGERGLKLKPGRGVNLPGSHLDVAALTEEDLAAL 331
Query: 842 LFGVEQGVDMIFASFIR 892
V + D++ SF++
Sbjct: 332 DVVVAE-ADLVAFSFVQ 347
>UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma
citri|Rep: Pyruvate kinase - Spiroplasma citri
Length = 192
Score = 53.6 bits (123), Expect = 1e-05
Identities = 30/72 (41%), Positives = 38/72 (52%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
I T GP++ + + + GM R+NFSHG H I RE SAK+G P S
Sbjct: 16 ITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPIS 71
Query: 476 LAIALDTKGPEI 511
+ LDTKGPEI
Sbjct: 72 --VLLDTKGPEI 81
>UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium
perfringens|Rep: Pyruvate kinase - Clostridium
perfringens
Length = 364
Score = 53.2 bits (122), Expect = 1e-05
Identities = 52/210 (24%), Positives = 89/210 (42%), Gaps = 4/210 (1%)
Frame = +2
Query: 347 MEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLL 526
++ G N+ RMN SHG H R+ E + ++ I LD +G +IR
Sbjct: 34 VKGGGNIIRMNLSHGKH----------RDVECCIDYIRSNHKNVKILLDLQGNKIRVANN 83
Query: 527 EGGGSAEVELKKGETIKLTTSSDYQEK-GNADTIYVDYKNITNVVKPGN---RIFIDDGL 694
G ++ G+ + + Y N D + NI N N +I++ D
Sbjct: 84 IYG---TFKVNSGDLVYFCSEETYDAYLKNIDRNKLIPLNIKNKFIYNNTFKKIYMKDAT 140
Query: 695 ISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMI 874
+ I S + + ++ GG++ KG NLP + VSEKD D+ F ++ VD+I
Sbjct: 141 MEFIVISNNNGLIKTKVKLGGVVRKEKGCNLPNLDRKNWGVSEKDLEDIKFAIDNKVDII 200
Query: 875 FASFIRNGAXLHEIRGILGEKGKNIRSSPR 964
S+ E + I+ + K+ + P+
Sbjct: 201 DYSYCSYMEECREFKNIVFKNLKSNQFIPK 230
>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
tenax|Rep: Pyruvate kinase - Thermoproteus tenax
Length = 446
Score = 50.8 bits (116), Expect = 7e-05
Identities = 49/217 (22%), Positives = 95/217 (43%), Gaps = 2/217 (0%)
Frame = +2
Query: 296 ICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 475
+ T GP++ + + + V R+N SH S + R+ E++ S
Sbjct: 6 VATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGRY 58
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
+AI D +GP +RTGL+ +++ G + S EKG+ + V + V
Sbjct: 59 IAIIADLRGPSVRTGLMR-----PLQITAGARV----SFKLAEKGDG-FVPVPRREFFEV 108
Query: 656 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 835
++ G+ + + DG + + S + + + G++ S K + + G + E+D
Sbjct: 109 IEEGDEVLMLDGKLVLRIISAAQTSAEAESLSSGVISSNKAIVVKGKEYHIEQPVEEDIR 168
Query: 836 DL--LFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
L L VD + S +R+GA + ++R ++ E G
Sbjct: 169 ALQTLSRFRDDVDYVALSLVRDGADVRKMRSVVEEAG 205
>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
Pyruvate kinase - Mycobacterium sp. (strain JLS)
Length = 615
Score = 48.8 bits (111), Expect = 3e-04
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +2
Query: 602 EKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGS 769
+ G A I + + +PG +I DDG I +V D L I+ G LGS
Sbjct: 354 DHGGAPRIGCTLPEVFDHARPGEKIRFDDGRIGGEIVAVERDALRVRIDRTAPGGSKLGS 413
Query: 770 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKG 940
KGVN+P + + A+++KD DL V D++ SF++ + + ++ L G
Sbjct: 414 AKGVNVPDTHLPIAALTDKDVEDLA-TVVAIADIVQISFVQRPSDITQLHDELHRLG 469
Score = 35.1 bits (77), Expect = 3.7
Identities = 21/60 (35%), Positives = 30/60 (50%)
Frame = +2
Query: 356 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 535
GMNVAR+N +H E + R A +S K +A+D GP++RTG + G
Sbjct: 164 GMNVARINCAHDDAEAWTAMAGHVRRAAESTGRK------CLVAMDLAGPKLRTGPIRPG 217
>UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep:
Pyruvate kinase - Corynebacterium efficiens
Length = 630
Score = 47.6 bits (108), Expect = 6e-04
Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 12/144 (8%)
Frame = +2
Query: 539 SAEVELKKGETIKLTTSSDYQEK----GNADTIYVDYKNITNVVKPGNRIFIDDGLISII 706
S + LK G + LT+ + G I +K G+R+ DDG I+ +
Sbjct: 331 SQRINLKVGNRLFLTSEEVVYDPSAGHGRIPKISCTLPEAVGAIKVGHRVLFDDGSIAAV 390
Query: 707 C--------QSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQG 862
C V +T G L + KG+NLP + LP+++E+D L F V +
Sbjct: 391 CIDRREHDGHHVVELEVTRARPQGVNLAAYKGINLPDSELPLPSLTEEDLRHLRF-VAKH 449
Query: 863 VDMIFASFIRNGAXLHEIRGILGE 934
D++ SFIR+ + + L +
Sbjct: 450 ADIVNVSFIRDTGDVEYVLDALAQ 473
>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 710
Score = 46.4 bits (105), Expect = 0.001
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 8/124 (6%)
Frame = +2
Query: 548 VELKKGETIKLTTSSDYQEKG----NADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 715
V LK G+ + +T E A + + + VKPG I DDG I + +
Sbjct: 437 VRLKVGDLLVITREGSLDEPSVTVPGAHRLTCPSGYLFDSVKPGETIGFDDGKIWGVIKG 496
Query: 716 VSADTLTCTIEN----GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFAS 883
S + +I + G LGS K +N+P + ++ KD DL + V DM+ S
Sbjct: 497 TSPSEVIVSITHARPKGTKLGSEKSINIPQSDIHFKGLTSKDIKDLDY-VASHADMVGIS 555
Query: 884 FIRN 895
FIR+
Sbjct: 556 FIRD 559
>UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 506
Score = 46.0 bits (104), Expect = 0.002
Identities = 49/186 (26%), Positives = 77/186 (41%), Gaps = 3/186 (1%)
Frame = +2
Query: 347 MEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLL 526
+ GMN AR+N +H I + R A S G P I +D GP+ R +
Sbjct: 161 LRKGMNCARVNCAHDDPATWEAMIEHLRAA----SHITGQP--CKILMDLGGPKPRIADI 214
Query: 527 EGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS-- 700
V + G+ ++LTT E G I ++ G R++IDDG
Sbjct: 215 ---FPETVRVHSGDRLRLTTEI-CPEGGEIPQFTCSLPEIVPQLEVGQRVWIDDGRTGGR 270
Query: 701 IICQSVSADTLTCT-IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIF 877
I+ + LT T + G L KG+N P + L ++ D+ L F D+I
Sbjct: 271 IVSKDAQGVELTITHCKEGQRLKVAKGLNFPDSDLRLCPLTASDREHLAFACRY-ADIIG 329
Query: 878 ASFIRN 895
S++++
Sbjct: 330 YSYVQS 335
>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
bacterium HTCC2170|Rep: Pyruvate kinase -
Flavobacteriales bacterium HTCC2170
Length = 624
Score = 45.2 bits (102), Expect = 0.003
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
Frame = +2
Query: 659 KPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGIPVDLPAVSEK 826
K G I+ DDG I I + V+A+ + I + G L + KG+NLP + + ++ K
Sbjct: 377 KKGEPIYFDDGKIEGIIEKVTAEDIVVKITHAKDKGSKLKADKGINLPKSDLKISGLTNK 436
Query: 827 DKSDLLFGVEQGVDMIFASFIRN 895
D+ D+ F + + D + SF+ +
Sbjct: 437 DREDIKF-IAKHADAVNFSFVNS 458
Score = 37.9 bits (84), Expect = 0.52
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
A+ ++ + + GMN AR+N +H + E + I N + A K K IA+D
Sbjct: 143 AAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKKC------KIAMD 196
Query: 494 TKGPEIRTG-LLEG 532
GP++RTG ++EG
Sbjct: 197 LSGPKLRTGPMVEG 210
>UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba
histolytica HM-1:IMSS|Rep: pyruvate kinase - Entamoeba
histolytica HM-1:IMSS
Length = 321
Score = 43.6 bits (98), Expect = 0.010
Identities = 35/138 (25%), Positives = 69/138 (50%), Gaps = 2/138 (1%)
Frame = +2
Query: 482 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVK 661
I +D +G +IR + + L K ++++LT + ++ I++ N ++
Sbjct: 54 IYVDLQGSKIRISRSQ----PNLILTKDQSVELTIKAPTKD---TKAIHIGNPNTIKLLS 106
Query: 662 PGNRIFIDDGLISIICQSVS-ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSD 838
G + IDDG + I+ S+ ++T T+ GG L KG NL P +SE+D ++
Sbjct: 107 QGTHVKIDDGRMEIVVNSIKDSETAIATVIKGGELKPGKGFNLQPHPFVQNQLSERD-AE 165
Query: 839 LLFGVEQGVDMIFA-SFI 889
++ ++ ++ FA SF+
Sbjct: 166 IVEKLKDVKEVCFALSFV 183
>UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_267, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 314
Score = 43.2 bits (97), Expect = 0.014
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Frame = +2
Query: 437 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA 616
+K++ + F +AI +DT+G EI G L SA+ E GE I + + +
Sbjct: 184 KKAFLTEQEKGFVVAIMMDTEGSEIHMGELGSAPSAKTE--DGE-IWIFSVQTFDSPRPE 240
Query: 617 DTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 763
TI ++Y VK G+ + +D G++ + + + D + C + G+L
Sbjct: 241 STININYDGFAEDVKVGDELLVDSGMVRFDVIEKIGPD-VKCRCTDPGLL 289
>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 626
Score = 42.7 bits (96), Expect = 0.018
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Frame = +2
Query: 620 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 787
TI + + V PG ++ DDG I + + V D I++ G L + KG+NL
Sbjct: 373 TISCTMPEVVSQVHPGESVWFDDGKIGGVIEKVETDRFWVKIQHARPEGSKLRAGKGMNL 432
Query: 788 PGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 895
P +++ +++ D S L F + + D + SF+ +
Sbjct: 433 PDSQLNVSSLTPTDISHLTF-IAKHADAVQMSFVNS 467
Score = 39.5 bits (88), Expect = 0.17
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
++++ +++ ++ GMN R+N +H E E I N + A++ + S + +D
Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207
Query: 494 TKGPEIRTGLLEGG 535
GP+IRTG +E G
Sbjct: 208 LGGPKIRTGEIEPG 221
>UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archaeon
GZfos3D4|Rep: Pyruvate kinase - uncultured archaeon
GZfos3D4
Length = 588
Score = 42.7 bits (96), Expect = 0.018
Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 26/213 (12%)
Frame = +2
Query: 359 MNVARMNFS-HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 535
++V RMN + H E + RE +K G ++A+ D GP+IR G G
Sbjct: 2 VDVIRMNMAFHKGGETERAIFKWLRENKK------GMTKNVAVLGDLPGPKIRLG---GV 52
Query: 536 GSAEVELKKGETIKL---TTSSDYQEKGNADTIYVDYKNITNVVKPGNR----------- 673
G A +++ KGE L + + K ++ V+ K VVK N
Sbjct: 53 GGA-IKVSKGEHFDLYFRKRNEVSKSKRAGASVLVNDKPFEEVVKKINEYDGIGDYIGES 111
Query: 674 --------IFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 829
I I DG + + S + C +E G + KGV + +D P+ ++D
Sbjct: 112 IRNNKDVVISIADGSVILKAVGESEGVVECEVEKEGEIKDHKGVTIKRAELDAPSFEQRD 171
Query: 830 KSDLLFGVEQGVD---MIFASFIRNGAXLHEIR 919
K L F +++G D + SF+++ + ++R
Sbjct: 172 KEALRFLLDEGGDFLGFVGVSFVKDAEDVLKVR 204
Score = 39.9 bits (89), Expect = 0.13
Identities = 21/53 (39%), Positives = 29/53 (54%)
Frame = +1
Query: 952 IISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKRYPXPKNMIAKCXGL 1110
+I+K E Q N + II +DGIMVARG LG+ + + P + I K L
Sbjct: 256 VIAKIETKQAWRNIDEIIDVADGIMVARGDLGLQVDPQEVPSIQKKIIKLCNL 308
>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyruvate kinase, barrel domain containing protein -
Tetrahymena thermophila SB210
Length = 747
Score = 40.7 bits (91), Expect = 0.074
Identities = 38/129 (29%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 335 LXXXMEXGMNVARMNFSHGSHEYHAETIRNCREA-EKSYSAKLGSPFSLAIALDTKGPEI 511
L +E G+N +N ++ + + T+R R+A EK + +L P + + KG +
Sbjct: 84 LKSMVEAGLNSFMVNMAYCTPDLLV-TLRKHRDALEKEFDIQL--PITCVL----KGTLV 136
Query: 512 RTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDG 691
R G L E+ L+KG+ ++ + ++ GN+ VD K I VK GN+I ID G
Sbjct: 137 RIGTLM---QPEIFLRKGQEYRIVLN--HKVLGNSLYCAVDDKEIIRRVKVGNQILIDYG 191
Query: 692 LISIICQSV 718
IS+ + +
Sbjct: 192 QISMTIKRI 200
Score = 37.5 bits (83), Expect = 0.69
Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Frame = +1
Query: 949 QIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIP-XKRYPXPKNMIAKC 1101
+I++K + + + N I+ SDG+ +ARG L + +P K + K MI KC
Sbjct: 483 RIMAKIQTPESVENFEEIVKASDGVQIARGYLTVHMPVEKLFAKQKEMIHKC 534
>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
(strain A1501)
Length = 625
Score = 38.7 bits (86), Expect = 0.30
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 11/132 (8%)
Frame = +2
Query: 554 LKKGETIKLTTSS---DYQEKGNADTIYVD--YKNITNVVKPGNRIFIDDGLISIICQSV 718
L+ G+ + LT D NA+T + ++ V G+ ++ DDG I +
Sbjct: 337 LRVGDLLALTADDQPIDPPSNDNAETARIGCTLPHVLAAVAAGDPVWFDDGKIGARVEKA 396
Query: 719 SADTLTCTI------ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFA 880
SAD L I L S KG+N P + + A +E D L F + D++
Sbjct: 397 SADALILRITQIAHASGRAKLASDKGINFPDNALPVRAPTEDDIETLAFAAKH-ADIVQM 455
Query: 881 SFIRNGAXLHEI 916
SF + + E+
Sbjct: 456 SFANSAEDVIEL 467
Score = 36.3 bits (80), Expect = 1.6
Identities = 23/69 (33%), Positives = 37/69 (53%)
Frame = +2
Query: 314 ASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 493
A+ N ++ ++ GM+ AR+N +H + I + R AEK+ LG +ALD
Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203
Query: 494 TKGPEIRTG 520
GP++RTG
Sbjct: 204 LAGPKLRTG 212
>UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
ATCC BAA-548
Length = 121
Score = 37.9 bits (84), Expect = 0.52
Identities = 28/67 (41%), Positives = 36/67 (53%)
Frame = +2
Query: 476 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 655
LAI +DTKGP IRT L+ A + LK G+ + LT + QEK + V+Y T
Sbjct: 57 LAIMVDTKGPNIRTCNLD----APLALKIGDKLDLTGETVPQEK----AVQVNYSKFTAE 108
Query: 656 VKPGNRI 676
V G RI
Sbjct: 109 VPVGARI 115
>UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep:
CG12229-PA - Drosophila melanogaster (Fruit fly)
Length = 571
Score = 37.5 bits (83), Expect = 0.69
Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 12/152 (7%)
Frame = +2
Query: 371 RMNFSHGSHEYHAETIRNCREAEKS-----------YSAKLGSPFSLAIALDTKGPEIRT 517
R +G++ +H +T+ N + K+ +SA+ + +AL+ G R
Sbjct: 91 RRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLALEINGECCRV 150
Query: 518 GLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNITNVVKPGNRIFIDDGL 694
G L + V L +G + LTT Y+ KG + +YV + + V+ G+ + I +
Sbjct: 151 GRLRN--NCTVMLARGGVVTLTTDESYRYKGFKEIVYVINLRCYLASVQLGDIVMIGREV 208
Query: 695 ISIICQSVSADTLTCTIENGGMLGSRKGVNLP 790
+ +++ + LT I + G++ S + LP
Sbjct: 209 RGKVVKTL-REALTVMIIDAGLVASYDFIELP 239
>UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_00239360;
n=1; Tetrahymena thermophila SB210|Rep: hypothetical
protein TTHERM_00239360 - Tetrahymena thermophila SB210
Length = 1220
Score = 37.1 bits (82), Expect = 0.91
Identities = 19/66 (28%), Positives = 34/66 (51%)
Frame = +2
Query: 443 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 622
S S + + F+ LDT GP + + ++++K E+IK+ + YQ KGN+
Sbjct: 924 SKSQQNSNQFNQGNQLDTLGPFENNAVQNSLENISLKIEKNESIKIQSKDIYQNKGNSQF 983
Query: 623 IYVDYK 640
+ +D K
Sbjct: 984 LNIDQK 989
>UniRef50_Q9LSA0 Cluster: Emb|CAB62463.1; n=3; Arabidopsis
thaliana|Rep: Emb|CAB62463.1 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 653
Score = 36.7 bits (81), Expect = 1.2
Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = -1
Query: 945 FFPFSPRXPRISCSXAPXRMNDAKIISTPCS--TPKSRSDLSFSETAGRSTGMPGRLTPF 772
F + P +SCS +P R + ++S PCS P SD+ T R P +P
Sbjct: 342 FDRYKASPPSVSCSPSPTRSDSHALVSHPCSRHLPPHPSDI---PTGRRKESYPEEYSPC 398
Query: 771 RDPSIPP 751
+D S PP
Sbjct: 399 QDFSPPP 405
>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
Pyruvate kinase - Geobacillus kaustophilus
Length = 660
Score = 35.9 bits (79), Expect = 2.1
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Frame = +2
Query: 356 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG-LLEG 532
GM++AR+N ++GS E + R+AEK +L I +D GP+IR L
Sbjct: 197 GMDIARINCAYGSPETWEALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKIRVDRLAVN 255
Query: 533 GGSAEVELKK 562
G ++ +KK
Sbjct: 256 AGPMKLSVKK 265
>UniRef50_A7EYT0 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 375
Score = 35.9 bits (79), Expect = 2.1
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Frame = -1
Query: 897 PXRMNDAKIISTPCSTPKSRSDLSFSETA--GRSTGMPGRLTPFRDPSIPPFSMVHVRV 727
P N STP STP S S S+T RS MPG LTP + P + +R+
Sbjct: 285 PPDQNQDSSTSTPTSTPSSSDSDSNSQTPIFARSPPMPGLLTPSEILTKAPLDKIKIRI 343
>UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium
cellulolyticum H10|Rep: S-layer-like region -
Clostridium cellulolyticum H10
Length = 1382
Score = 35.5 bits (78), Expect = 2.8
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Frame = +2
Query: 482 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDYKNI--TN 652
I ++ ++R +L+G E+E+ KGE I +T S E D I V NI T
Sbjct: 243 IKIEKNNNKLRIVILDGNTVKEIEIAKGEEIIVTGSVGTLEIATPDVIVKVIAANISDTK 302
Query: 653 VVKPGNRIFID-DGLISIICQSVSADTLTCTIENGGMLGS 769
VV IF+D + I + + SA+ E G ++ +
Sbjct: 303 VVSANASIFVDKESKIKSVSINNSAENTAIKAEKGAVVNT 342
>UniRef50_Q9RHY8 Cluster: ORF1 protein; n=1; Corynebacterium
ammoniagenes|Rep: ORF1 protein - Corynebacterium
ammoniagenes (Brevibacterium ammoniagenes)
Length = 320
Score = 34.7 bits (76), Expect = 4.8
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Frame = -3
Query: 790 GQVDAFPGSEHTSVFNGTRKSVSADRLTDDRDEAIIDEDSVSWLHDIRYVLVVHVNCISI 611
G VD G ++ V T +V + L DD I +DS D++ L H +
Sbjct: 140 GTVDLILGEDYPGVMPLTDNTVEREHLIDDELVLITPQDSTLTFQDVK-ELAGHEGQPEV 198
Query: 610 AFLL--IIRTCRQLYSLSLLQFDFS*AAAFQEPSSDLRSFSVQ 488
F L + + R+ + LQ+ F F+ P L+++ V+
Sbjct: 199 RFALDSVEFSLRRFFQAYCLQYGFEPKVDFETPDPFLQTYLVR 241
>UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding
subunit ClpA; n=1; Shewanella baltica OS223|Rep:
ATP-dependent Clp protease, ATP-binding subunit ClpA -
Shewanella baltica OS223
Length = 66
Score = 34.3 bits (75), Expect = 6.4
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
Frame = +2
Query: 434 AEKSYSAKLGS-PFSLAIALDTKGP---EIRTGLLEGGGSAEVELKKGETI 574
AEK Y +G+ P + + K P EI G+LE GG A V++K+GE +
Sbjct: 3 AEKGYDKNMGARPMARVVTELIKRPLADEILFGVLESGGVAHVDVKEGELV 53
>UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter
vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter
vinelandii AvOP
Length = 165
Score = 33.9 bits (74), Expect = 8.5
Identities = 16/51 (31%), Positives = 25/51 (49%)
Frame = +2
Query: 281 RLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAETIRNCRE 433
R + + T G A+ + ++ G++V R+NFSHG E H RE
Sbjct: 3 RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 957,523,057
Number of Sequences: 1657284
Number of extensions: 17499441
Number of successful extensions: 54613
Number of sequences better than 10.0: 169
Number of HSP's better than 10.0 without gapping: 51508
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54313
length of database: 575,637,011
effective HSP length: 102
effective length of database: 406,594,043
effective search space used: 121571618857
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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