Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP25_F_D08
(1206 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 298 2e-80
M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 298 2e-80
BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 298 2e-80
BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 298 2e-80
BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 298 2e-80
BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 298 2e-80
AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 298 2e-80
M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 297 4e-80
BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 295 3e-79
AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 295 3e-79
M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 276 1e-73
U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 272 1e-72
U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 272 1e-72
D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 272 1e-72
BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 272 1e-72
AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 272 1e-72
AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 272 1e-72
AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 272 1e-72
AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 272 1e-72
BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 116 2e-25
BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. 98 5e-20
AM260536-1|CAJ97431.1| 1266|Homo sapiens ponsin protein. 33 2.1
AL158165-7|CAI14379.1| 1292|Homo sapiens sorbin and SH3 domain c... 33 2.1
AF356525-1|AAK37563.1| 1292|Homo sapiens sorbin and SH3 domain c... 33 2.1
M59465-1|AAA51550.1| 790|Homo sapiens A20 protein. 32 3.6
BC114480-1|AAI14481.1| 790|Homo sapiens tumor necrosis factor, ... 32 3.6
BC113871-1|AAI13872.1| 790|Homo sapiens tumor necrosis factor, ... 32 3.6
AY248754-1|AAO61093.1| 790|Homo sapiens tumor necrosis factor, ... 32 3.6
AL357060-4|CAH72937.1| 790|Homo sapiens tumor necrosis factor, ... 32 3.6
AL157444-1|CAB75664.1| 636|Homo sapiens hypothetical protein pr... 32 3.6
>X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein.
Length = 531
Score = 298 bits (732), Expect = 2e-80
Identities = 142/240 (59%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase
protein.
Length = 531
Score = 298 bits (732), Expect = 2e-80
Identities = 142/240 (59%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 298 bits (732), Expect = 2e-80
Identities = 142/240 (59%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 298 bits (732), Expect = 2e-80
Identities = 142/240 (59%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 298 bits (732), Expect = 2e-80
Identities = 142/240 (59%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 298 bits (732), Expect = 2e-80
Identities = 142/240 (59%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 298 bits (732), Expect = 2e-80
Identities = 142/240 (59%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene
encoding cytosolic thyroid hormone-binding protein,
complete cds. ).
Length = 531
Score = 297 bits (730), Expect = 4e-80
Identities = 141/240 (58%), Positives = 182/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AE+ELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPYLYRPVAVALDTKGPEIRTGLIKGSGTAELELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 295 bits (723), Expect = 3e-79
Identities = 141/240 (58%), Positives = 181/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG L S+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLVSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform
1 variant protein.
Length = 531
Score = 295 bits (723), Expect = 3e-79
Identities = 141/240 (58%), Positives = 181/240 (75%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS R +G ICT GPASR+V L ++ GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 413 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 592
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 593 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 772
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKRKGADFLVTEVENGGSLGSK 206
Query: 773 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKNIR 952
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + + E+R +LGEKGKNI+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVREVRKVLGEKGKNIK 266
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 261 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 317
>M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein.
Length = 543
Score = 276 bits (676), Expect = 1e-73
Identities = 135/243 (55%), Positives = 175/243 (72%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 39 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 98
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
TI N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 99 TIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 155
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q +S + L +ENGG+L
Sbjct: 156 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKISPEGLVTQVENGGVL 215
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 216 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 275
Query: 944 NIR 952
I+
Sbjct: 276 GIK 278
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 273 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 329
>U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L
isoenzyme protein.
Length = 566
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 62 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 121
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 122 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 178
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 179 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 238
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 239 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 298
Query: 944 NIR 952
I+
Sbjct: 299 GIK 301
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 296 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 352
>U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R
isoenzyme protein.
Length = 587
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 83 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 142
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 143 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 199
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 200 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 259
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 260 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 319
Query: 944 NIR 952
I+
Sbjct: 320 GIK 322
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 317 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 373
>D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein.
Length = 599
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 95 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 154
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 155 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 211
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 212 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 271
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 272 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 331
Query: 944 NIR 952
I+
Sbjct: 332 GIK 334
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 329 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 385
>BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 306
Query: 944 NIR 952
I+
Sbjct: 307 GIK 309
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 304 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 360
>AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 306
Query: 944 NIR 952
I+
Sbjct: 307 GIK 309
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 304 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 360
>AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 585
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 81 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 140
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 141 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 197
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 198 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 257
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 258 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 317
Query: 944 NIR 952
I+
Sbjct: 318 GIK 320
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 315 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 371
>AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 565
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 61 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 120
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 121 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 177
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 178 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 237
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 238 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 297
Query: 944 NIR 952
I+
Sbjct: 298 GIK 300
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 295 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 351
>AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein.
Length = 574
Score = 272 bits (668), Expect = 1e-72
Identities = 133/243 (54%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Frame = +2
Query: 233 LQHXCGLDIDSKSSYIRLSGXICTXGPASRNVAVLXXXMEXGMNVARMNFSHGSHEYHAE 412
L+H C LDIDS+ R + I T GPASR+V L ++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 413 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 583
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 584 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 763
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 764 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGK 943
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 306
Query: 944 NIR 952
I+
Sbjct: 307 GIK 309
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
+G +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 304 EGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 360
>BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein.
Length = 343
Score = 116 bits (279), Expect = 2e-25
Identities = 54/77 (70%), Positives = 62/77 (80%)
Frame = +2
Query: 722 ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 901
AD L +ENGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR +
Sbjct: 2 ADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAS 61
Query: 902 XLHEIRGILGEKGKNIR 952
+HE+R +LGEKGKNI+
Sbjct: 62 DVHEVRKVLGEKGKNIK 78
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 73 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 129
>BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein.
Length = 366
Score = 98.3 bits (234), Expect = 5e-20
Identities = 45/62 (72%), Positives = 52/62 (83%)
Frame = +2
Query: 767 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAXLHEIRGILGEKGKN 946
S+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKN
Sbjct: 40 SKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKN 99
Query: 947 IR 952
I+
Sbjct: 100 IK 101
Score = 56.4 bits (130), Expect = 2e-07
Identities = 29/57 (50%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +1
Query: 934 KGEEHQIISKXENHQGMVN*NXIIXESDGIMVARGXLGIXIPXKR-YPXPKNMIAKC 1101
KG+ +IISK ENH+G+ + I+ SDGIMVARG LGI IP ++ + K MI +C
Sbjct: 96 KGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 152
>AM260536-1|CAJ97431.1| 1266|Homo sapiens ponsin protein.
Length = 1266
Score = 33.1 bits (72), Expect = 2.1
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 7/75 (9%)
Frame = -1
Query: 954 DLMFFPFSPRXPRISCSXAPXRMNDAKIIS-TPCSTPKSRSDLS------FSETAGRSTG 796
D M PFS R S + +P + +K+I+ P S P SR LS SE + G
Sbjct: 890 DYMDLPFSSSPSR-SATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVG 948
Query: 795 MPGRLTPFRDPSIPP 751
+PGR + P +PP
Sbjct: 949 VPGRRSLALTPPLPP 963
>AL158165-7|CAI14379.1| 1292|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1292
Score = 33.1 bits (72), Expect = 2.1
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 7/75 (9%)
Frame = -1
Query: 954 DLMFFPFSPRXPRISCSXAPXRMNDAKIIS-TPCSTPKSRSDLS------FSETAGRSTG 796
D M PFS R S + +P + +K+I+ P S P SR LS SE + G
Sbjct: 936 DYMDLPFSSSPSR-SATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVG 994
Query: 795 MPGRLTPFRDPSIPP 751
+PGR + P +PP
Sbjct: 995 VPGRRSLALTPPLPP 1009
>AF356525-1|AAK37563.1| 1292|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1292
Score = 33.1 bits (72), Expect = 2.1
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 7/75 (9%)
Frame = -1
Query: 954 DLMFFPFSPRXPRISCSXAPXRMNDAKIIS-TPCSTPKSRSDLS------FSETAGRSTG 796
D M PFS R S + +P + +K+I+ P S P SR LS SE + G
Sbjct: 936 DYMDLPFSSSPSR-SATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVG 994
Query: 795 MPGRLTPFRDPSIPP 751
+PGR + P +PP
Sbjct: 995 VPGRRSLALTPPLPP 1009
>M59465-1|AAA51550.1| 790|Homo sapiens A20 protein.
Length = 790
Score = 32.3 bits (70), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = -3
Query: 229 GADVGDWRLXNCTRFGIXKLHKSLHFVED*LKLMRHAQKEWN*TXXKARLEXRXQH 62
G D G L N + L K ++ V+D +L++H K+W + R E Q+
Sbjct: 316 GWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQN 371
>BC114480-1|AAI14481.1| 790|Homo sapiens tumor necrosis factor,
alpha-induced protein 3 protein.
Length = 790
Score = 32.3 bits (70), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = -3
Query: 229 GADVGDWRLXNCTRFGIXKLHKSLHFVED*LKLMRHAQKEWN*TXXKARLEXRXQH 62
G D G L N + L K ++ V+D +L++H K+W + R E Q+
Sbjct: 316 GWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQN 371
>BC113871-1|AAI13872.1| 790|Homo sapiens tumor necrosis factor,
alpha-induced protein 3 protein.
Length = 790
Score = 32.3 bits (70), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = -3
Query: 229 GADVGDWRLXNCTRFGIXKLHKSLHFVED*LKLMRHAQKEWN*TXXKARLEXRXQH 62
G D G L N + L K ++ V+D +L++H K+W + R E Q+
Sbjct: 316 GWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQN 371
>AY248754-1|AAO61093.1| 790|Homo sapiens tumor necrosis factor,
alpha-induced protein 3 protein.
Length = 790
Score = 32.3 bits (70), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = -3
Query: 229 GADVGDWRLXNCTRFGIXKLHKSLHFVED*LKLMRHAQKEWN*TXXKARLEXRXQH 62
G D G L N + L K ++ V+D +L++H K+W + R E Q+
Sbjct: 316 GWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQN 371
>AL357060-4|CAH72937.1| 790|Homo sapiens tumor necrosis factor,
alpha-induced protein 3 protein.
Length = 790
Score = 32.3 bits (70), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = -3
Query: 229 GADVGDWRLXNCTRFGIXKLHKSLHFVED*LKLMRHAQKEWN*TXXKARLEXRXQH 62
G D G L N + L K ++ V+D +L++H K+W + R E Q+
Sbjct: 316 GWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQN 371
>AL157444-1|CAB75664.1| 636|Homo sapiens hypothetical protein
protein.
Length = 636
Score = 32.3 bits (70), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = -3
Query: 229 GADVGDWRLXNCTRFGIXKLHKSLHFVED*LKLMRHAQKEWN*TXXKARLEXRXQH 62
G D G L N + L K ++ V+D +L++H K+W + R E Q+
Sbjct: 162 GWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQN 217
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 140,572,405
Number of Sequences: 237096
Number of extensions: 2642913
Number of successful extensions: 7302
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6905
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7292
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17009285070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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