Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP24_F_P19
(920 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4; ... 196 9e-49
UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-... 179 8e-44
UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocystei... 157 3e-37
UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA... 157 5e-37
UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine... 137 4e-31
UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome sh... 119 9e-26
UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella ve... 108 2e-22
UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1; ... 107 5e-22
UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=3... 105 1e-21
UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;... 98 3e-19
UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG... 95 2e-18
UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;... 95 2e-18
UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase, putat... 95 2e-18
UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1; Ja... 93 7e-18
UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2; ... 90 8e-17
UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 88 3e-16
UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;... 88 3e-16
UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 87 5e-16
UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of s... 86 1e-15
UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2; ... 85 2e-15
UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1; ... 85 2e-15
UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4; ... 82 2e-14
UniRef50_UPI000050FD2A Cluster: COG2040: Homocysteine/selenocyst... 81 4e-14
UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransfera... 79 2e-13
UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1; Pl... 78 3e-13
UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-13
UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase, putat... 73 1e-11
UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11
UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase; ... 72 2e-11
UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1; ... 71 6e-11
UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;... 65 2e-09
UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1; ... 64 5e-09
UniRef50_Q2TXK9 Cluster: Predicted protein; n=2; Trichocomaceae|... 60 8e-08
UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2; ... 58 4e-07
UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of str... 54 4e-06
UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Re... 52 2e-05
UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2; ... 52 2e-05
UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1; ... 52 3e-05
UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family... 50 8e-05
UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Re... 50 1e-04
UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein NCU007... 49 1e-04
UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase, putat... 49 2e-04
UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine syntha... 48 3e-04
UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1; ... 47 8e-04
UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family... 46 0.001
UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransfera... 44 0.004
UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine m... 44 0.005
UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5; ... 44 0.007
UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25; Cyanobacteri... 43 0.010
UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=... 43 0.010
UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase, putat... 43 0.010
UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1; ... 43 0.010
UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase, putat... 42 0.017
UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1; ... 41 0.039
UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine ... 41 0.051
UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9... 41 0.051
UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=... 40 0.068
UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransfera... 40 0.068
UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3; ... 40 0.089
UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;... 40 0.089
UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;... 39 0.16
UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family... 39 0.16
UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1; ... 39 0.16
UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1; ... 39 0.16
UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=... 38 0.27
UniRef50_A5UPF4 Cluster: Methionine synthase; n=4; Chloroflexace... 38 0.27
UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2; ... 38 0.36
UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 38 0.36
UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine ... 38 0.48
UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;... 38 0.48
UniRef50_Q6AL45 Cluster: Related to 5-methyltetrahydrofolate--ho... 37 0.63
UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:... 37 0.83
UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1; ... 37 0.83
UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=... 37 0.83
UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2; ... 36 1.5
UniRef50_A7RIN6 Cluster: Predicted protein; n=2; Nematostella ve... 36 1.5
UniRef50_Q55786 Cluster: Methionine synthase; n=5; Cyanobacteria... 36 1.5
UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine syntha... 36 1.9
UniRef50_A5ZSP9 Cluster: Putative uncharacterized protein; n=1; ... 35 2.5
UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4; ... 35 2.5
UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4; ... 35 2.5
UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 35 3.4
UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella suc... 34 4.4
UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium... 34 4.4
UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine... 34 5.9
UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep... 34 5.9
UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2; ... 34 5.9
UniRef50_A5Z6N8 Cluster: Putative uncharacterized protein; n=1; ... 34 5.9
UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep... 34 5.9
UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 34 5.9
UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associa... 33 7.8
UniRef50_Q9WYA5 Cluster: 5-methyltetrahydrofolate S-homocysteine... 33 7.8
UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine... 33 7.8
UniRef50_Q8ESE8 Cluster: Betaine-homocysteine methyltransferase;... 33 7.8
UniRef50_Q748M7 Cluster: Methylenetetrahydrofolate reductase; n=... 33 7.8
UniRef50_Q0IB34 Cluster: Possible MFS family transporter, putati... 33 7.8
UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:... 33 7.8
UniRef50_A6TTI3 Cluster: Homocysteine S-methyltransferase; n=2; ... 33 7.8
UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine ... 33 7.8
>UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4;
Endopterygota|Rep: Homocysteine S-methyltransferase -
Bombyx mori (Silk moth)
Length = 325
Score = 196 bits (477), Expect = 9e-49
Identities = 89/141 (63%), Positives = 111/141 (78%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
+ VLDGGFSTQL+CH GH DGDPL SARF+ THP +V+NTHLDFLRAG+D+I TNTYQA
Sbjct: 11 VFVLDGGFSTQLTCHAGHTADGDPLGSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 70
Query: 439 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 618
SV+G V+HL +T E+ YELI AV+ A+ AR LYL+E ++ + PLI GSVGPYGA+
Sbjct: 71 SVDGLVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAY 130
Query: 619 LHDGSEYDGSYADTTSIXTMR 681
LHD SEY G+YAD T+ T++
Sbjct: 131 LHDTSEYTGNYADNTTKETIK 151
>UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-PA
- Drosophila melanogaster (Fruit fly)
Length = 331
Score = 179 bits (436), Expect = 8e-44
Identities = 85/147 (57%), Positives = 112/147 (76%)
Frame = +1
Query: 241 NTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLII 420
N + I+V GGFS+QL+ +V +DGDPLW +RF T+P V+ THLDFLR GAD+I+
Sbjct: 8 NWDTKPILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIIL 67
Query: 421 TNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSV 600
TNTYQ+SVEGFV++LGVT+E+G ELI ++VQLAKQA+ YL E ++ +PLI+GS+
Sbjct: 68 TNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAES-ALPLIMGSI 126
Query: 601 GPYGAHLHDGSEYDGSYADTTSIXTMR 681
GPYGA+LHDGSEY G+YAD S +R
Sbjct: 127 GPYGAYLHDGSEYTGNYADKMSKEELR 153
>UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocysteine
S-methyltransferase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to homocysteine S-methyltransferase -
Nasonia vitripennis
Length = 341
Score = 157 bits (382), Expect = 3e-37
Identities = 72/140 (51%), Positives = 106/140 (75%), Gaps = 1/140 (0%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
+++DGGFSTQL HVG VIDGDPLW++RF++++P+ V THLD+LRAG+ +I T TYQAS
Sbjct: 24 IIIDGGFSTQLVTHVGEVIDGDPLWTSRFLYSNPDAVFQTHLDYLRAGSHVIETATYQAS 83
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
+ G+V++L T+E+ +LI AV+LAK+A +Y EE + ++ P++ GS+GPY A+L
Sbjct: 84 IPGYVKYLDRTEEEALQLIKTAVELAKKAVRVYKEEIKGKDVSNPEPMVAGSIGPYAAYL 143
Query: 622 HDGSEY-DGSYADTTSIXTM 678
HD SEY GSYA+ S+ ++
Sbjct: 144 HDCSEYTGGSYANIESMDSI 163
>UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to
CG10621-PA - Apis mellifera
Length = 320
Score = 157 bits (380), Expect = 5e-37
Identities = 73/140 (52%), Positives = 100/140 (71%), Gaps = 4/140 (2%)
Frame = +1
Query: 256 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 435
++ +LDGGF QLS HV +DGDPLW+++F+ T+PN V THLDFL+AGAD+I TNTYQ
Sbjct: 2 NVKILDGGFGAQLSTHVNEKVDGDPLWTSKFLVTNPNAVYATHLDFLKAGADIIETNTYQ 61
Query: 436 ASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI----PLIVGSVG 603
AS+ ++HL ++KE+ +L+ +AV LAK A Y +E + N+D+ P+IV S G
Sbjct: 62 ASIPSLMKHLSISKEESIKLLHKAVHLAKTAVNDYTKE---VINNNDVENKNPMIVASCG 118
Query: 604 PYGAHLHDGSEYDGSYADTT 663
PYGA LHDGSEY+G+Y T
Sbjct: 119 PYGASLHDGSEYNGAYGKIT 138
>UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine
S-methyltransferase domain; n=7; Euteleostomi|Rep: Novel
protein containing a homocysteine S-methyltransferase
domain - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 318
Score = 137 bits (331), Expect = 4e-31
Identities = 66/154 (42%), Positives = 100/154 (64%)
Frame = +1
Query: 265 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 444
+LDGG +T+L G + GDPLWSAR +HT P + + H +L++G+D+I T TYQAS+
Sbjct: 14 ILDGGLATELEAS-GFQLQGDPLWSARVLHTDPQAIKDVHYRYLQSGSDVITTATYQASI 72
Query: 445 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLH 624
EGFV++LGV E+ ++ AVQLAK+ + ++ + + + PL+ GSVGPYG+ LH
Sbjct: 73 EGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFISQ--SPMSDRREPLVAGSVGPYGSFLH 130
Query: 625 DGSEYDGSYADTTSIXTMRXMASGPEFXPWLKAG 726
DGSEY G+Y D ++ ++ P+ +KAG
Sbjct: 131 DGSEYTGAYEDKMTVEELKDW-HRPQIQCLVKAG 163
>UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 1
SCAF14770, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 372
Score = 119 bits (287), Expect = 9e-26
Identities = 68/161 (42%), Positives = 93/161 (57%), Gaps = 22/161 (13%)
Frame = +1
Query: 265 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 444
+LDGG +T L H + GDPLWSAR ++T+P + + H FL +GAD+I T TYQASV
Sbjct: 18 ILDGGLATDLEAQGVH-LQGDPLWSARLLYTNPQAIRDAHCRFLLSGADVISTATYQASV 76
Query: 445 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYL--EEYRDYVQNDD-------------- 576
EGF++HL V+ E ELI VQLAK+A ++ VQ+ +
Sbjct: 77 EGFMDHLNVSSEGAKELIMSGVQLAKEAVESFVPGTNPNTTVQSGEGKVNSEGSEGLAGQ 136
Query: 577 ------IPLIVGSVGPYGAHLHDGSEYDGSYADTTSIXTMR 681
PL+ GS+GPYGA LH+GSEY G YA+ S+ ++
Sbjct: 137 CSSGRRCPLVAGSLGPYGAFLHNGSEYTGDYAEKMSVQELK 177
>UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 265
Score = 108 bits (259), Expect = 2e-22
Identities = 53/121 (43%), Positives = 77/121 (63%)
Frame = +1
Query: 316 IDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYEL 495
+ GDPLWSAR + +P V H FL G+D+I T TYQAS+ GF +HLGVT ++ +L
Sbjct: 3 MQGDPLWSARVLVENPEAVKQVHKSFLTHGSDIITTATYQASISGFCKHLGVTADEARKL 62
Query: 496 IARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTSIXT 675
I R V +A+++ ++E+ D ++ + P + GSV PYG DGSEY G+Y DT +I
Sbjct: 63 IQRGVHIARES----VDEFWD--KHSNSPQVAGSVCPYGTCQSDGSEYHGNYVDTMTIKN 116
Query: 676 M 678
+
Sbjct: 117 L 117
>UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 319
Score = 107 bits (256), Expect = 5e-22
Identities = 60/149 (40%), Positives = 90/149 (60%), Gaps = 9/149 (6%)
Frame = +1
Query: 232 SSENTEAPHI-VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGA 408
S+ +P I +++DG +T L H+G I G LWSA + + P+ + THLD+ RAGA
Sbjct: 7 STHLNSSPDIPLLIDGALATYLE-HLGADISGS-LWSASILLSRPDLIKKTHLDYYRAGA 64
Query: 409 DLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYL--------EEYRDYV 564
++ IT +YQAS+ G V+HLG+ + + +++ ++VQLA +AR Y+ E D
Sbjct: 65 NIAITASYQASIPGLVKHLGLGENEAKDVVKKSVQLAIEARDEYVQSKLEESCERSVDAA 124
Query: 565 QNDDIPLIVGSVGPYGAHLHDGSEYDGSY 651
+ + GSVGPYGA+L DGSEY G Y
Sbjct: 125 SLREDLFVAGSVGPYGAYLSDGSEYRGDY 153
>UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=30;
Magnoliophyta|Rep: Homocysteine S-methyltransferase 3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 347
Score = 105 bits (253), Expect = 1e-21
Identities = 58/148 (39%), Positives = 88/148 (59%), Gaps = 9/148 (6%)
Frame = +1
Query: 265 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 444
V+DGGF+T+L H + DPLWSA+ + T P+ V HLD+L +GA++IIT +YQA++
Sbjct: 25 VVDGGFATELQRHGADI--NDPLWSAKCLITSPHLVTKVHLDYLESGANIIITASYQATI 82
Query: 445 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEE---------YRDYVQNDDIPLIVGS 597
+GFV G++ + L+ R+V++ +AR ++ Y I L+ S
Sbjct: 83 QGFVAK-GLSVGEAENLLRRSVEITYEAREIFYNRCTKGSWDFAYAGKASRRPI-LVAAS 140
Query: 598 VGPYGAHLHDGSEYDGSYADTTSIXTMR 681
VG YGA+L DGSEY G Y D+ S T++
Sbjct: 141 VGSYGAYLADGSEYSGIYGDSVSKETLK 168
>UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;
Bacteria|Rep: Homocysteine S-methyltransferase -
Escherichia coli (strain K12)
Length = 310
Score = 97.9 bits (233), Expect = 3e-19
Identities = 55/131 (41%), Positives = 77/131 (58%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
I++LDG +T+L ++ D LWSA+ + +P + HLD+ RAGA IT +YQA
Sbjct: 16 ILLLDGAMATELEARGCNLADS--LWSAKVLVENPELIREVHLDYYRAGAQCAITASYQA 73
Query: 439 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 618
+ GF G+ + Q LI ++V+LA++AR YL E L+ GSVGPYGA+
Sbjct: 74 TPAGFAAR-GLDEAQSKALIGKSVELARKAREAYLAEN----PQAGTLLVAGSVGPYGAY 128
Query: 619 LHDGSEYDGSY 651
L DGSEY G Y
Sbjct: 129 LADGSEYRGDY 139
>UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG
protein - Bacillus subtilis
Length = 315
Score = 95.5 bits (227), Expect = 2e-18
Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
++VLDG +T+L ++ D LWSA+ + P + H D+ AGAD IT +YQ+
Sbjct: 13 LIVLDGAMATELERKGCNL--NDSLWSAKILMEEPELIKQVHTDYFAAGADCAITASYQS 70
Query: 439 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY--LEEYRDYVQNDDIPLIVGSVGPYG 612
+ EGF G+++ + LI +V +A +AR + LEE R N P+I S+GPYG
Sbjct: 71 TFEGFAAR-GLSEAEARRLIELSVSIAAEARDEFWSLEENR---LNRPKPIIAASIGPYG 126
Query: 613 AHLHDGSEYDGSYA 654
A+L DGSEY G+YA
Sbjct: 127 AYLADGSEYRGNYA 140
>UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;
Streptococcus|Rep: Homocysteine S-methyltransferase -
Streptococcus agalactiae H36B
Length = 351
Score = 95.5 bits (227), Expect = 2e-18
Identities = 54/139 (38%), Positives = 80/139 (57%), Gaps = 1/139 (0%)
Frame = +1
Query: 238 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 417
E E+ ++L G T+L G + G LWS +++ P + H D++RAGAD++
Sbjct: 43 ELLESKKALILHGALGTELESR-GCDVSGK-LWSDKYLIEDPAAIQTIHEDYIRAGADIV 100
Query: 418 ITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI-PLIVG 594
T+TYQA+++G + +GV++ Q +LI VQLAK R + +++ I PLI G
Sbjct: 101 TTSTYQATLQGLAQ-VGVSESQAEDLIRLTVQLAKAVREQVWKSLTKEEKSERIYPLISG 159
Query: 595 SVGPYGAHLHDGSEYDGSY 651
VGPY A L DGSEY G Y
Sbjct: 160 DVGPYAAFLADGSEYTGLY 178
>UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Leishmania|Rep: Homocysteine
S-methyltransferase, putative - Leishmania major
Length = 339
Score = 95.5 bits (227), Expect = 2e-18
Identities = 53/132 (40%), Positives = 79/132 (59%)
Frame = +1
Query: 256 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 435
++V+LDGG +T+L + DPLWS + + P ++ N L +LRAGA IIT +YQ
Sbjct: 29 YVVMLDGGLATELETRGCDL--RDPLWSGKVLLESPQQLQNVALAYLRAGARCIITASYQ 86
Query: 436 ASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGA 615
+ + +EH +T++ I +V++A+ AR +L R+ Q I + GSVGPYGA
Sbjct: 87 ITPQSLMEHRRLTEDAAVAAIEESVRIAQSARERHL---REKPQAAPI-FVAGSVGPYGA 142
Query: 616 HLHDGSEYDGSY 651
+L DGSEY G Y
Sbjct: 143 YLADGSEYRGDY 154
>UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1;
Janibacter sp. HTCC2649|Rep: Homocysteine
methyltransferase - Janibacter sp. HTCC2649
Length = 305
Score = 93.5 bits (222), Expect = 7e-18
Identities = 57/128 (44%), Positives = 76/128 (59%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
VVLDGGFST L GH + G LWSAR + P+EVV H F+ AGA+++I+ +YQAS
Sbjct: 23 VVLDGGFSTALEAR-GHDLSGR-LWSARLLRQAPSEVVAAHRTFVDAGAEIVISASYQAS 80
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
G+V G+T+E+ + +++LA+Q D L+ SVGPYGAHL
Sbjct: 81 HAGYVA-AGLTEEECDADLDASIELARQGA-------------DGRALVAASVGPYGAHL 126
Query: 622 HDGSEYDG 645
DGSEY G
Sbjct: 127 ADGSEYTG 134
>UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus reuteri|Rep: Homocysteine
S-methyltransferase - Lactobacillus reuteri F275
Length = 310
Score = 89.8 bits (213), Expect = 8e-17
Identities = 51/130 (39%), Positives = 78/130 (60%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
+++DG ST L +G + LW+A + P V H ++ +AG L IT+TYQA+
Sbjct: 12 LLIDGAMSTALE-QLG-ADTNNSLWTASVLANQPALVKKVHQEYFKAGDRLAITDTYQAN 69
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
V F+++ G +K++ + LI RAV LAK+AR Y +E Y + G++GPYGA+L
Sbjct: 70 VPAFIKN-GYSKQEAHSLIQRAVVLAKEARDEYQQETGIY------NYVAGALGPYGAYL 122
Query: 622 HDGSEYDGSY 651
+GSEY G+Y
Sbjct: 123 ANGSEYSGAY 132
>UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus|Rep: Homocysteine S-methyltransferase -
Lactobacillus acidophilus
Length = 310
Score = 88.2 bits (209), Expect = 3e-16
Identities = 51/133 (38%), Positives = 78/133 (58%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
++LDG ST L V + LW+A + ++V H+++ ++GA + ITNTYQA+
Sbjct: 12 LILDGAMSTALEKQ--GVNTNNDLWTAVALENDLDKVYKVHMNYFKSGAQMTITNTYQAN 69
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
V+ F +H G + E +LI AVQ+AK+AR ++Y+ Q + SVGPYGA+L
Sbjct: 70 VQAFKKH-GYSDEHTKKLITDAVQIAKKAR----DDYQ--TQTGKHNWVAASVGPYGAYL 122
Query: 622 HDGSEYDGSYADT 660
DG E+ G Y+ T
Sbjct: 123 SDGDEFRGDYSLT 135
>UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;
Actinomycetales|Rep: Homocysteine S-methyltransferase -
Mycobacterium tuberculosis
Length = 302
Score = 88.2 bits (209), Expect = 3e-16
Identities = 53/131 (40%), Positives = 73/131 (55%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
+++ DGG +T+L GH + DPLWSAR + P+ + H + RAGA + T +YQA
Sbjct: 8 VLISDGGLATELEAR-GHDLS-DPLWSARLLVDAPHAITAVHTAYFRAGAQIATTASYQA 65
Query: 439 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 618
S EGF G+ + L+ R+V+LA+ A RD V + + SVGPYGA
Sbjct: 66 SFEGFAAR-GIGHDDATVLLRRSVELAQAA--------RDEVGVGGLS-VAASVGPYGAA 115
Query: 619 LHDGSEYDGSY 651
L DGSEY G Y
Sbjct: 116 LADGSEYRGCY 126
>UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2;
Bacteria|Rep: Homocysteine S-methyltransferase -
Lactobacillus plantarum
Length = 309
Score = 87.4 bits (207), Expect = 5e-16
Identities = 55/135 (40%), Positives = 74/135 (54%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
VV DG +T+L V LWSA + HP+ + H +L AGA ++ TNTYQA+
Sbjct: 13 VVSDGAMATELEKR--GVATNSALWSATAMLDHPDAIQAVHQSYLDAGAKIMTTNTYQAN 70
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
V F E G+ Q +LI +AV +A AR +V + +I GS+GPYGA+L
Sbjct: 71 VPAF-EQAGIAAVQARQLIQQAVTIAHTARD------ASHVTD---AVIAGSIGPYGAYL 120
Query: 622 HDGSEYDGSYADTTS 666
DGSEY G+Y T S
Sbjct: 121 ADGSEYTGAYQLTPS 135
>UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome A of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 351
Score = 86.2 bits (204), Expect = 1e-15
Identities = 50/142 (35%), Positives = 80/142 (56%), Gaps = 12/142 (8%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGD-------PLWSARFIHTHPNEVVNTHLDFLRAGADLII 420
+V+DG TQL ++ D PLWSA + +P + H D++ +GA++I
Sbjct: 14 LVIDGALGTQLETKFSKLLQQDNINIQTHPLWSALVLLKNPELIQEVHYDYMCSGANIIT 73
Query: 421 TNTYQASVEGFVEHL-GVTKEQGYELI-ARAVQLAKQARTLYLEEY---RDYVQNDDIPL 585
T+TYQAS G +E+ G+ + + +A++LA AR+ YLE + + N +I
Sbjct: 74 TSTYQASKRGLLEYAPGIENDDEVNAVYDKAIELAVDARSQYLENMGKGMNTLTNKEI-F 132
Query: 586 IVGSVGPYGAHLHDGSEYDGSY 651
I GS+GP+GA+L +G+EY G Y
Sbjct: 133 ICGSIGPFGAYLANGAEYTGKY 154
>UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus delbrueckii subsp. bulgaricus|Rep:
Homocysteine S-methyltransferase - Lactobacillus
delbrueckii subsp. bulgaricus (strain ATCC 11842 /
DSM20081)
Length = 310
Score = 85.4 bits (202), Expect = 2e-15
Identities = 51/131 (38%), Positives = 77/131 (58%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
V LDG ST L G + D LW+A+ + +P+ V H ++ +AGA + IT++YQAS
Sbjct: 13 VTLDGSMSTPLEAW-GEDTNSD-LWTAKALADNPDLVYRVHQEYFKAGARVTITDSYQAS 70
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
+ F++H G++++ LI + +A +AR + E + N + GSVGPYGA+L
Sbjct: 71 LPAFMKH-GLSEDAARALIRESAAVAIKARDDF--EKETGIHN----FVAGSVGPYGAYL 123
Query: 622 HDGSEYDGSYA 654
DGSEY G YA
Sbjct: 124 ADGSEYRGDYA 134
>UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep: Homocysteine
S-methyltransferase - Granulobacter bethesdensis (strain
ATCC BAA-1260 / CGDNIH1)
Length = 313
Score = 85.0 bits (201), Expect = 2e-15
Identities = 50/132 (37%), Positives = 76/132 (57%), Gaps = 1/132 (0%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
++LDG +T+L G+ +D DPLWS R + +P + H +L AGAD I T +YQ S
Sbjct: 15 LLLDGALATELE-RAGYHLD-DPLWSGRLLLDNPAAIAAVHRAYLEAGADCIETASYQLS 72
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQAR-TLYLEEYRDYVQNDDIPLIVGSVGPYGAH 618
+ G ++ G+++ + ++A A +LA R ++ +N PL+ GS+GPYGA
Sbjct: 73 LPG-LQRRGLSRGRAMSVLADAARLACSVRDDVWAGLPAAQRRNRIRPLVAGSLGPYGAC 131
Query: 619 LHDGSEYDGSYA 654
DGSEY G YA
Sbjct: 132 QADGSEYTGRYA 143
>UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4;
n=1; Candida albicans|Rep: Putative uncharacterized
protein SAM4 - Candida albicans (Yeast)
Length = 311
Score = 81.8 bits (193), Expect = 2e-14
Identities = 49/138 (35%), Positives = 73/138 (52%), Gaps = 4/138 (2%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVG----HVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNT 429
+V+DG T+L + ++ G PLWS + + +P V HLD++ GAD+IIT+T
Sbjct: 13 LVIDGALGTELERLLPTTSTYLPSGSPLWSGQVLIKNPELVEQVHLDYINVGADMIITST 72
Query: 430 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 609
YQ S +++G +Q L A+ +AK A + RD V +I GS+GPY
Sbjct: 73 YQTSYASLHKYIGYDMDQAIALWNSALNVAKNA---VKKSGRDDV------IIAGSIGPY 123
Query: 610 GAHLHDGSEYDGSYADTT 663
L +GSEY+G Y T
Sbjct: 124 ATLLANGSEYNGDYQGVT 141
>UniRef50_UPI000050FD2A Cluster: COG2040:
Homocysteine/selenocysteine methylase
(S-methylmethionine-dependent); n=1; Brevibacterium
linens BL2|Rep: COG2040: Homocysteine/selenocysteine
methylase (S-methylmethionine-dependent) -
Brevibacterium linens BL2
Length = 308
Score = 81.0 bits (191), Expect = 4e-14
Identities = 50/130 (38%), Positives = 70/130 (53%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
+V+DGG T L G + + LWSA + P+ + H DF+RAGA ++ T +YQA+
Sbjct: 19 LVIDGGLGTALESR-GIDLSHE-LWSAALLRDSPDTLAEVHADFIRAGAQIVTTASYQAT 76
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
GF E + E+G LIAR+V++A A L+ GSVGPYGA L
Sbjct: 77 PLGF-ERASIPAEEGLRLIARSVEIAAGAGD---------------ALVAGSVGPYGAAL 120
Query: 622 HDGSEYDGSY 651
+G+EY G Y
Sbjct: 121 GNGAEYTGDY 130
>UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransferase;
n=1; Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305|Rep: Putative homocysteine
S-methyltransferase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 301
Score = 78.6 bits (185), Expect = 2e-13
Identities = 50/138 (36%), Positives = 74/138 (53%)
Frame = +1
Query: 238 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 417
E +A +VLDGG +T L G + LWS+ + +P ++ H F GAD++
Sbjct: 5 EKLKAQSPLVLDGGLATTLE-QAGCSLKTS-LWSSEVLKNNPTQIKQAHQAFTDVGADIL 62
Query: 418 ITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGS 597
+T+TYQAS + F + +G+ + +L AV +A T D +IVGS
Sbjct: 63 LTSTYQASYQTFSD-IGMKATEIDQLYNTAVNQIMEATT-------------DTQVIVGS 108
Query: 598 VGPYGAHLHDGSEYDGSY 651
+GPYGA+L DGSEY G+Y
Sbjct: 109 LGPYGAYLSDGSEYTGAY 126
>UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Homocysteine
methyltransferase - Plesiocystis pacifica SIR-1
Length = 325
Score = 78.2 bits (184), Expect = 3e-13
Identities = 52/129 (40%), Positives = 71/129 (55%)
Frame = +1
Query: 265 VLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASV 444
VLDGG +T L G +D DPLWSAR + P + H + AGAD++ T +YQAS+
Sbjct: 22 VLDGGLATSLEA-CGCDLD-DPLWSARLLLDDPEALRTVHRRWRDAGADILATASYQASL 79
Query: 445 EGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLH 624
G + G+++ + L+ +V L + A +E N PLI SVG YGA+L
Sbjct: 80 PG-LRAKGLSEARAKALLRESVTLTRAA----ADE-----ANAPRPLIAASVGSYGAYLA 129
Query: 625 DGSEYDGSY 651
DGSEY G Y
Sbjct: 130 DGSEYRGGY 138
>UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 347
Score = 63.7 bits (148), Expect(2) = 4e-13
Identities = 42/118 (35%), Positives = 64/118 (54%), Gaps = 18/118 (15%)
Frame = +1
Query: 382 HLDFLRAGADLIITNTYQA-SVEGFVEHL---GVTKEQGYE-----LIARAVQLAKQART 534
HLD+L AGAD+IIT +YQ S +V L G+ E E + ++V++A +AR
Sbjct: 90 HLDYLEAGADIIITASYQVNSAYIYVNRLLFRGLKLEASLEEKVKPCLGKSVEIACEARK 149
Query: 535 LYLEEYRDYVQNDDIP---------LIVGSVGPYGAHLHDGSEYDGSYADTTSIXTMR 681
+Y + ++ +D L+ SVG YGA+L DGSEY G Y D ++ T++
Sbjct: 150 MYYDRCIEFACDDXEDGRILKHRPILVAASVGSYGAYLADGSEYSGIYGDEITVETLK 207
Score = 34.3 bits (75), Expect(2) = 4e-13
Identities = 17/49 (34%), Positives = 29/49 (59%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAG 405
+ V+DGG +T+L H + DPLWSA+ + + P+ ++ T F+ G
Sbjct: 22 VAVIDGGLATELERHGADL--NDPLWSAKCLLSSPH-LIRTGSRFVNLG 67
>UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 326
Score = 75.4 bits (177), Expect = 2e-12
Identities = 46/144 (31%), Positives = 74/144 (51%), Gaps = 10/144 (6%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVG----HVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNT 429
VVLDG T L + ++ PLWS + + P + H ++ AG+++I T+T
Sbjct: 10 VVLDGALGTALEDLIDPSAPYLPSKSPLWSGQVLLDAPELIQKVHEMYIGAGSEVIFTST 69
Query: 430 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI------PLIV 591
YQ S + +H ++ EQ E+ R++ L + A L ++E Y + + I
Sbjct: 70 YQLSYDSLRKHTTLSDEQILEVWQRSIDLVR-AAALSIDETARYTKEKESRGEPGKVHIA 128
Query: 592 GSVGPYGAHLHDGSEYDGSYADTT 663
GS+GPY A+L +GSEY G Y + T
Sbjct: 129 GSIGPYAAYLANGSEYTGDYGNVT 152
>UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Filobasidiella neoformans|Rep:
Homocysteine S-methyltransferase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 381
Score = 72.5 bits (170), Expect = 1e-11
Identities = 43/135 (31%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
Frame = +1
Query: 256 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 435
+I+VLDGG T L +G I PLW + + T+P+ + H +++ GADL+ T TYQ
Sbjct: 4 NILVLDGGMGTTLES-LGVDISS-PLWGSEALRTNPDVIRKVHEGYVQGGADLVETATYQ 61
Query: 436 ASVEGFVEHLGVTKEQGYELIARAVQLAKQ---ARTLYLEEYRDYVQNDDIPLIVGSVGP 606
+ + +HL +E+ ++ V+L + + EE+ + + +V S GP
Sbjct: 62 LTPQNLCDHLHCPREEAECILCSGVKLVASCIASCSSRNEEHNTKSKGGNKSKVVLSFGP 121
Query: 607 YGAHLHDGSEYDGSY 651
YG+ L G EY G Y
Sbjct: 122 YGSTLQPGQEYGGIY 136
>UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 313
Score = 72.5 bits (170), Expect = 1e-11
Identities = 45/138 (32%), Positives = 67/138 (48%), Gaps = 3/138 (2%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHV---GHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 432
+VLDGG QL + DPLWS R + P+ + + H FL AG D++ T+TY
Sbjct: 7 LVLDGGLGIQLETLAEKRNFAVKNDPLWSGRALIEAPDLIEDVHKSFLEAGCDIVTTSTY 66
Query: 433 QASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYG 612
Q S ++ T Q EL A++V + QA + + R + G++GPYG
Sbjct: 67 QISRASLKKYTDFTDAQIEELWAKSVDVCWQACKFHESKAR----------VCGAIGPYG 116
Query: 613 AHLHDGSEYDGSYADTTS 666
L + +EY G Y T+
Sbjct: 117 GFLANYAEYTGEYGLITN 134
>UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase;
n=1; Pichia stipitis|Rep: AdoMet-homocysteine
methyltransferase - Pichia stipitis (Yeast)
Length = 337
Score = 72.1 bits (169), Expect = 2e-11
Identities = 44/140 (31%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVID----GDPLWSARFIHTHPNEVVNTHLDFL-RAGADLIITN 426
+VLDG T+L + PLWS + PN + N H ++L +A D +I++
Sbjct: 13 LVLDGAMGTELEACIPKDSKIQPRKHPLWSGLVLLNEPNLIKNVHYNYLEQADVDALISS 72
Query: 427 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPL-IVGSVG 603
TYQ S EH + EQ + +++ + + A + +YR N + I+GS+G
Sbjct: 73 TYQISYPSLKEHTDLDDEQIRGIWKKSIDVVEDA----ILQYRSKNSNSKKKIYIIGSIG 128
Query: 604 PYGAHLHDGSEYDGSYADTT 663
PY +L DGSEY G Y + +
Sbjct: 129 PYATYLADGSEYTGDYKNAS 148
>UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 448
Score = 70.5 bits (165), Expect = 6e-11
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 12/146 (8%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEV---------VNTHLDFLRAGAD 411
I +LDGG +T L + + PLWSAR + ++V + HL +L+AGA
Sbjct: 19 IGILDGGLATYLEDGLDFDLSKGPLWSARLLDEKEDDVSDGKGQKGIFDAHLHYLQAGAG 78
Query: 412 LIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY-LEEYRDYVQN--DDIP 582
+I T TYQAS+E F + L+++AV LA A + + + V + P
Sbjct: 79 IIGTATYQASLESFA-RANYDQVSASHLMSKAVDLACDALHAHNISNNKVGVASAASARP 137
Query: 583 LIVGSVGPYGAHLHDGSEYDGSYADT 660
L+ S+GPYGA L +G+EY G Y T
Sbjct: 138 LLSLSLGPYGAMLSNGAEYTGDYRRT 163
>UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;
Pezizomycotina|Rep: Contig An15c0240, complete genome -
Aspergillus niger
Length = 353
Score = 65.3 bits (152), Expect = 2e-09
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGD--PLWSARFIHTHPNEVVNTHLDFLRAGA-DLIITNT 429
I++LDGG T L H PLWS+ + + P+ +++ DF A D+++T T
Sbjct: 6 ILILDGGLGTSLQDHYNITFSSSTTPLWSSHLMISDPSTLLSCQRDFTTTAAVDVLLTAT 65
Query: 430 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 609
YQ S EGF TK + +A RT L+ VQN + + S+GPY
Sbjct: 66 YQVSPEGFQR----TKTPSHPTGIPRESIAGYLRTA-LDVAGQAVQNTSASVAL-SLGPY 119
Query: 610 GAHLHDGSEYDGSY 651
GA + G EY G Y
Sbjct: 120 GACMIPGQEYSGKY 133
>UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1785
Score = 64.1 bits (149), Expect = 5e-09
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Frame = +1
Query: 253 PHIVVLDGGFSTQLS-CHVGHVIDGD-PLWSARFIHTHPNEVVNTHLDFLRAGADLIITN 426
P+I++LDG T L G PLWS+ + +HP + H ++ AGAD+++T
Sbjct: 6 PNILLLDGAMGTVLEEPPYGFTFSAQTPLWSSHLLLSHPTTLSEIHRSYVDAGADIVLTA 65
Query: 427 TYQASVEGFVEHLGV---------TKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI 579
TYQAS EGF V E+ R + + R+ Y + +
Sbjct: 66 TYQASFEGFARTAIVPANVPADHKQDERDGHATYRPMDATRYMRSAIPLAYSSFNFSSKP 125
Query: 580 PLIVGSVGPYGAHLHD-GSEYDGSYADTTS 666
P + S+GPYGA + +EY G Y + S
Sbjct: 126 PRVALSLGPYGATMCPVSAEYTGIYPEEMS 155
>UniRef50_Q2TXK9 Cluster: Predicted protein; n=2;
Trichocomaceae|Rep: Predicted protein - Aspergillus
oryzae
Length = 376
Score = 60.1 bits (139), Expect = 8e-08
Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 4/137 (2%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVI--DGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 432
I++LDGG T L ++ PLWSA + + P+ + H F GAD+I+T TY
Sbjct: 8 ILLLDGGLGTTLGDPPHNITFTAETPLWSAHLLISSPSTLEEVHKAFATVGADIILTATY 67
Query: 433 QASVEGF-VEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPY 609
Q S EGF + T + + A+ LA++A + + + S+GPY
Sbjct: 68 QTSFEGFTLTDPRYTADDAAHFMRSAIPLARRAGS----------SSGRTVKVALSLGPY 117
Query: 610 GAHLHD-GSEYDGSYAD 657
GA + G+EY G Y +
Sbjct: 118 GATMSPVGAEYTGLYPE 134
>UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 369
Score = 57.6 bits (133), Expect = 4e-07
Identities = 44/143 (30%), Positives = 63/143 (44%), Gaps = 10/143 (6%)
Frame = +1
Query: 259 IVVLDGGFSTQLS-CHVGHVIDGDPLWSARFI---HTH-PNEVVNTHLDFLRAGADLIIT 423
I +LDGG T L H + +PLWS++ + H H P ++ T F+ AGAD+++T
Sbjct: 7 IHLLDGGLGTTLGDSHQVQFTEKEPLWSSQLLIPTHPHGPKTLLATQKSFVDAGADILLT 66
Query: 424 NTYQASVEGF-----VEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLI 588
TYQ S EGF H + G + + + + D I
Sbjct: 67 ATYQTSYEGFGGSGYAVHSHSSSNSGKADGDKEEVNGIMRSAVDIASDAFSTKKDSNGKI 126
Query: 589 VGSVGPYGAHLHDGSEYDGSYAD 657
S+G YGA + G EY G Y D
Sbjct: 127 ALSLGAYGAIMTPGQEYTGKYDD 149
>UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1;
Marinobacter sp. ELB17|Rep: Putative uncharacterized
protein - Marinobacter sp. ELB17
Length = 303
Score = 54.8 bits (126), Expect = 3e-06
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
+V+LDGG ++ +V LWS +H P+ V H DF+RAGA + NTY A
Sbjct: 4 VVLLDGGLGQEIYRRAANV--SSALWSVAVMHEQPDVVTAVHSDFIRAGAKTLSLNTYAA 61
Query: 439 SV-----EGFVEHLGVTKEQGYELIARAVQ 513
+ G +E L + +EL+ +AV+
Sbjct: 62 TPSRLLRHGQLEQLAAIHQNAFELLGQAVK 91
>UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 348
Score = 54.4 bits (125), Expect = 4e-06
Identities = 36/121 (29%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Frame = +1
Query: 304 VGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTK-E 480
V +D P W + N + H D++ AGAD++ + +YQAS+EG ++ V +
Sbjct: 58 VNRALDEHPEW-LESSQDNSNLLYRIHKDYVVAGADIVTSASYQASLEGTIKAGAVQRWP 116
Query: 481 QGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADT 660
+ ++ ++ QL ++A T + + L+ SVGP+GA L G EY+G Y
Sbjct: 117 EALWMLRKSEQLVRKAVTEAKVKRK--------VLLAASVGPFGAWLGGGQEYNGDYTGY 168
Query: 661 T 663
T
Sbjct: 169 T 169
>UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Rep:
AFR410Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 370
Score = 52.4 bits (120), Expect = 2e-05
Identities = 46/141 (32%), Positives = 66/141 (46%), Gaps = 5/141 (3%)
Frame = +1
Query: 256 HIVVLDGGFSTQLSCHVGHVIDGDPLWS-ARFIHTHP---NEVVNTHLDFLRAGADLIIT 423
+++V+DGG +L V PLWS A F+ + + + +F AG+ I T
Sbjct: 58 NVLVMDGGMGVELERRGMDV--KSPLWSTAPFLRGDRAALDTIRGLYREFRAAGSRGIST 115
Query: 424 NTYQASVEGFVEHLG-VTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSV 600
TYQAS V++ G V+ YE Q+ ++ RDY I+GSV
Sbjct: 116 LTYQASFHSMVKYSGSVSSRADYEKFLE--QVVDFTYRECVDPARDY--------IIGSV 165
Query: 601 GPYGAHLHDGSEYDGSYADTT 663
GPY A L +G+EY G Y T
Sbjct: 166 GPYAAFLCNGAEYTGDYGFET 186
>UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2;
Gammaproteobacteria|Rep: Homocysteine
S-methyltransferase - Psychromonas ingrahamii (strain
37)
Length = 310
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/117 (32%), Positives = 62/117 (52%), Gaps = 2/117 (1%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
++LDGG +L +G P WSA+ + P+ + H F+ AGA++I TNTY +
Sbjct: 17 IILDGGMGRELK-RIGAPFQ-QPEWSAQALIESPHFISEVHKSFIEAGAEVITTNTY--A 72
Query: 442 VEGFVEHLGVTK--EQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 606
+ F H+G + EQG +LI A +LA++ ++E + IP ++GS P
Sbjct: 73 LVPF--HIGEKRFNEQGADLIKLAARLAREC----VKENSAVLVAGCIPPVLGSYRP 123
>UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 374
Score = 51.6 bits (118), Expect = 3e-05
Identities = 44/148 (29%), Positives = 62/148 (41%), Gaps = 17/148 (11%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVID-GDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 435
I +LDGG T L G V PLWS+ + + + +F AGAD+++T TYQ
Sbjct: 4 IKILDGGLGTTLEDRFGVVFTHAKPLWSSDLLVSDQETLQACQREFAAAGADVLLTATYQ 63
Query: 436 ASVEGFV-----EHL-GVTKEQ--------GYELIARAVQLAKQARTLYLEEYRDYVQ-- 567
SVE F EH G+ E+ +A A A R+
Sbjct: 64 VSVEAFARTKTPEHPDGIAPSSAMLPYLRGAVEIAEKAAAAAAAAAAAAAAAPRNETSAP 123
Query: 568 NDDIPLIVGSVGPYGAHLHDGSEYDGSY 651
+ + + GPYGA + G EY G+Y
Sbjct: 124 SPQPAELALACGPYGAAMTPGQEYTGAY 151
>UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family
protein; n=6; Vibrionales|Rep: Homocysteine
S-methyltransferase family protein - Vibrio splendidus
12B01
Length = 299
Score = 50.0 bits (114), Expect = 8e-05
Identities = 33/90 (36%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
+ +LDGG +L + PLWSA+ + P V H +F+ AGA+++ITN+Y A
Sbjct: 4 LTILDGGMGRELK-EIDAPFS-QPLWSAQALIEAPEFVSQAHQNFVDAGAEILITNSY-A 60
Query: 439 SVEGFVEHLG--VTKEQGYELIARAVQLAK 522
V HLG + +++G+EL A++ +LAK
Sbjct: 61 CVP---FHLGEELFEQRGFELAAQSGELAK 87
>UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Rep:
Mlr1281 protein - Rhizobium loti (Mesorhizobium loti)
Length = 301
Score = 49.6 bits (113), Expect = 1e-04
Identities = 30/91 (32%), Positives = 48/91 (52%)
Frame = +1
Query: 256 HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 435
++++ DGG +L + PLWSAR + P+ V + H +F+RAGA +I NTY
Sbjct: 3 NVILTDGGMGQELVRRSKS--EPTPLWSARVLIDEPDLVRDLHAEFIRAGARVITINTYS 60
Query: 436 ASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
A+ E ++ L R ++LA+QA
Sbjct: 61 ATPERLARE--GAEDLFKPLQKRGIELARQA 89
>UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein
NCU00799.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00799.1 - Neurospora crassa
Length = 361
Score = 49.2 bits (112), Expect = 1e-04
Identities = 45/145 (31%), Positives = 66/145 (45%), Gaps = 14/145 (9%)
Frame = +1
Query: 259 IVVLDGGFSTQLS-CHVGHVIDGDPLWSARFIHT-HPNEVVNTHLDFLRAGADLIITNTY 432
+ +LDGG T L H PLWS+ + + +++ + H F +AGA++I T TY
Sbjct: 7 VQILDGGMGTTLEDMHDITFSFETPLWSSHLLVSGEEDKLSDCHEAFKQAGANIISTATY 66
Query: 433 QASVEGFV------------EHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDD 576
Q S+ GF E G+ KE+ ++RAV LA A
Sbjct: 67 QISINGFAATKAPRSGTVDEEREGIEKEEIPRFLSRAVVLAANAAG----------TEGK 116
Query: 577 IPLIVGSVGPYGAHLHDGSEYDGSY 651
+ L S+GPYGA + +EY G Y
Sbjct: 117 VAL---SLGPYGATMIPSTEYSGRY 138
>UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase,
putative; n=2; Trypanosoma cruzi|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma cruzi
Length = 410
Score = 48.8 bits (111), Expect = 2e-04
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 24/156 (15%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
+++ DG T L +WS+ + + + V H ++ AG D+++T TYQ
Sbjct: 9 VLIKDGAMGTLLESWDVDYAKAGSMWSSSVLLSEMDLVKRAHRAYIDAGCDVLLTCTYQM 68
Query: 439 SVEGFVEHLGVTKEQGYELIARAVQ------------------LAKQARTLYLEEYRDYV 564
EG +K EL+ RAVQ AK+ RT ++ +R +
Sbjct: 69 HEEG----CAASKVTMCELVDRAVQAARHTMPQRKQKGLTEESTAKERRTGGIDVFRYAL 124
Query: 565 QN------DDIPLIVGSVGPYGAHLHDGSEYDGSYA 654
+ + + L+ GS+GPYG+ L G EY G Y+
Sbjct: 125 SSIKDNGQERVVLLAGSLGPYGSSLPGGQEYLGEYS 160
>UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=1; Salinibacter ruber DSM 13855|Rep:
Vitamin B12-dependent methionine synthase family protein
- Salinibacter ruber (strain DSM 13855)
Length = 320
Score = 48.4 bits (110), Expect = 3e-04
Identities = 41/115 (35%), Positives = 55/115 (47%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
V+LDGG +L G LWSA + P+ V H ++LRAGAD+I TNTY
Sbjct: 13 VLLDGGLGQEL-IRRGMPSTEPSLWSANALTEAPDLVQEVHEEYLRAGADVITTNTYATP 71
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 606
E E G+ + L A +LA++AR RD + +P I GS P
Sbjct: 72 PERLSE-AGL-DGRAEALNREAGRLAERARAAV---GRDALIAGSLPPIRGSYRP 121
>UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 323
Score = 48.0 bits (109), Expect = 3e-04
Identities = 32/114 (28%), Positives = 56/114 (49%)
Frame = +1
Query: 325 DPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIAR 504
D W + + N + + D++ +G+ ++ T TYQ S H V +GY+ + R
Sbjct: 47 DDFWDSETKTSDRNIIEGIYRDYITSGSRILSTITYQTSFALISTHTEVKTIEGYKQLIR 106
Query: 505 AVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTS 666
+ T + R + D+ ++GS+GP+GA L G+EY G+Y D+ S
Sbjct: 107 NI-------TSFC---RSAIGEDN--YLIGSIGPFGARL--GAEYTGNYGDSPS 146
>UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1;
Pseudoalteromonas atlantica T6c|Rep: Homocysteine
S-methyltransferase - Pseudoalteromonas atlantica
(strain T6c / BAA-1087)
Length = 304
Score = 46.8 bits (106), Expect = 8e-04
Identities = 39/131 (29%), Positives = 59/131 (45%)
Frame = +1
Query: 232 SSENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGAD 411
+S + I +LDGG +L D P+WSA + P V + H +F+ +GA
Sbjct: 3 ASTSASKSTITILDGGMGQELLRRSSR--DVTPMWSADIMLNEPELVRDLHREFINSGAR 60
Query: 412 LIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIV 591
+I NTY A+ + EQ L A++ A++A L Q DD+ +I
Sbjct: 61 VITLNTYTATPQRLKRENQF--EQFVHLHDAAMRAAQEAIAL--------TQRDDV-MIA 109
Query: 592 GSVGPYGAHLH 624
GS+ P A H
Sbjct: 110 GSLPPLVASYH 120
>UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family
protein; n=1; Alteromonas macleodii 'Deep ecotype'|Rep:
Homocysteine S-methyltransferase family protein -
Alteromonas macleodii 'Deep ecotype'
Length = 305
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
I +LDGG +L +G P WSA + P V + H FL AGA +I TNTY
Sbjct: 8 IQILDGGMGRELK-KIGAPFR-QPEWSALALMQSPELVSDVHTHFLNAGATVITTNTY-- 63
Query: 439 SVEGFVEHLG--VTKEQGYELIARAVQLAKQA 528
++ F H+G EQ ++L A +LA+ A
Sbjct: 64 ALVPF--HIGEQTFNEQAFKLAETAAKLARDA 93
>UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1;
Vibrio harveyi ATCC BAA-1116|Rep: Putative
uncharacterized protein - Vibrio harveyi ATCC BAA-1116
Length = 301
Score = 45.2 bits (102), Expect = 0.002
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 2/91 (2%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
+ +LDGG +L PLWSA+ + P V H +F++AGA++II N+Y A
Sbjct: 4 LTILDGGMGRELKRMSAPF--SQPLWSAQALIESPEFVYQAHDNFIQAGAEIIIANSY-A 60
Query: 439 SVEGFVEHLG--VTKEQGYELIARAVQLAKQ 525
V HLG + +QG +L A ++A++
Sbjct: 61 CVP---FHLGQELYDQQGSKLARFAAKIARE 88
>UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransferase
1; n=61; Eumetazoa|Rep: Betaine--homocysteine
S-methyltransferase 1 - Homo sapiens (Human)
Length = 406
Score = 44.4 bits (100), Expect = 0.004
Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +1
Query: 238 ENTEAPHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLI 417
E A IV+ DGGF L G+V G W+ HP V H +FLRAG++++
Sbjct: 15 ERLNAGEIVIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVM 71
Query: 418 ITNTYQASVEGFVEHLG---VTKEQGYELIARAVQLAKQ 525
T T+ AS E +E+ G + K G E+ A +A+Q
Sbjct: 72 QTFTFYAS-EDKLENRGNYVLEKISGQEVNEAACDIARQ 109
>UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine
methyltransferase, truncation; n=8;
Desulfuromonadales|Rep:
5-methyltetrahydrofolate-homocysteine methyltransferase,
truncation - Geobacter sulfurreducens
Length = 804
Score = 44.0 bits (99), Expect = 0.005
Identities = 32/92 (34%), Positives = 48/92 (52%)
Frame = +1
Query: 250 APHIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNT 429
A ++VLDG T L G P T P V H ++L AGAD+I+TNT
Sbjct: 10 AERVLVLDGAMGTMLQ-ERGLRPGQSP---EELNLTLPEVVAGVHREYLDAGADIIVTNT 65
Query: 430 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQ 525
+ S +EH G+ +++ E+ ARAV +A++
Sbjct: 66 FGGS-RAKLEHYGL-QDRVAEINARAVAIARE 95
>UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5;
Alphaproteobacteria|Rep: Homocysteine
S-methyltransferase - Dinoroseobacter shibae DFL 12
Length = 350
Score = 43.6 bits (98), Expect = 0.007
Identities = 26/66 (39%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Frame = +1
Query: 238 ENTEAP-HIVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADL 414
EN P I +LDGG +L G PLWS + P+ V H DF AGA++
Sbjct: 37 ENRNRPMDITLLDGGLGQELVRRAGRAT---PLWSMEALLNAPDLVRAVHDDFFAAGAEV 93
Query: 415 IITNTY 432
TNTY
Sbjct: 94 ATTNTY 99
>UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25;
Cyanobacteria|Rep: Methionine synthase - Synechococcus
sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 1224
Score = 43.2 bits (97), Expect = 0.010
Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 4/133 (3%)
Frame = +1
Query: 220 MTPPSSENTEAPHIVVLDGGFSTQLSCHVGHVID-GDPLWSA---RFIHTHPNEVVNTHL 387
MT P ++ + ++V DG + L D G P + T P V H
Sbjct: 1 MTHPFLQHLQE-RVIVFDGAMGSSLQAQNLTAADFGGPELEGCNEMLVLTKPEAVERVHR 59
Query: 388 DFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQ 567
FL GAD++ TNT+ A+ E+ G+ E+ YEL A +LAK+ ++
Sbjct: 60 GFLEVGADVVETNTFGATSIVLAEY-GI-PEKAYELNVAAARLAKRVAA-------EFAT 110
Query: 568 NDDIPLIVGSVGP 606
+ + GS+GP
Sbjct: 111 PEKPRFVAGSIGP 123
>UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Methylenetetrahydrofolate reductase - Herpetosiphon
aurantiacus ATCC 23779
Length = 617
Score = 43.2 bits (97), Expect = 0.010
Identities = 39/120 (32%), Positives = 60/120 (50%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
++ DG TQL G ID D + A + T P+ V H ++ AGAD+I TNTY A+
Sbjct: 14 LLCDGAMGTQL---YGRGIDFDECFDALNL-TQPDVVREIHQSYIEAGADIIETNTYGAN 69
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
+E G+ ++ ++ R ++LA++AR + LI G+VGP G L
Sbjct: 70 -RFKLEPFGLA-DKVRQINHRGMKLAREAREI----------AGTNTLIAGAVGPLGVLL 117
>UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Plesiocystis pacifica SIR-1|Rep:
Homocysteine S-methyltransferase, putative -
Plesiocystis pacifica SIR-1
Length = 322
Score = 43.2 bits (97), Expect = 0.010
Identities = 30/92 (32%), Positives = 51/92 (55%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
++LDG +T+L G ++ PL++AR + P+ +V H D+ AGA ++ TN++
Sbjct: 8 LLLDGALATELRRR-GFELEA-PLFAARALLEAPDLLVEIHRDYALAGAQVLSTNSFGLH 65
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTL 537
+ G+ + Q EL AR+V+L AR L
Sbjct: 66 A-ATLARAGMAERQA-ELAARSVELTFLARQL 95
>UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 306
Score = 43.2 bits (97), Expect = 0.010
Identities = 23/61 (37%), Positives = 29/61 (47%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
I +LDGG +L PLWS + + P V N H DF AGA +I NTY
Sbjct: 5 ITLLDGGMGQEL-IRRSSAAKPHPLWSLQVMMDEPELVANVHRDFCLAGARVICLNTYSV 63
Query: 439 S 441
+
Sbjct: 64 T 64
>UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Trypanosoma brucei|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma brucei
Length = 433
Score = 42.3 bits (95), Expect = 0.017
Identities = 44/159 (27%), Positives = 65/159 (40%), Gaps = 27/159 (16%)
Frame = +1
Query: 256 HIVVLDGGFSTQLS-CHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 432
H +DG T + C + G +WS + T V H +L GAD+I+TNTY
Sbjct: 23 HFFTMDGAVGTLVERCGLDPSKMGS-MWSTSALITDEEIVRYVHKSYLDVGADVILTNTY 81
Query: 433 QASVEGFVEHLGVTKEQ----GYELIARAVQLAKQARTLYLEEYRDYVQN---------- 570
Q G + GVT + ++ + + A T + + +V N
Sbjct: 82 QMHAAGCAQ-AGVTMNEVVNTAVRVLCDGITPERAAATKEAKVWAQHVMNNKRSEFVNVF 140
Query: 571 --------DD---IPLIV-GSVGPYGAHLHDGSEYDGSY 651
DD P++V GS+G YGA L + EY G Y
Sbjct: 141 APLFYGPRDDASKCPVLVGGSLGSYGASLGNAQEYRGEY 179
>UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 508
Score = 41.1 bits (92), Expect = 0.039
Identities = 22/70 (31%), Positives = 39/70 (55%)
Frame = +1
Query: 376 NTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYR 555
N HL +L AG ++I TNT+Q ++ E G++ + G ++ R + +A +A L Y
Sbjct: 44 NIHLSYLLAGCNVISTNTFQVNLHSLQEK-GISVQDGEGIVDRYIDIAHRA----LLRYE 98
Query: 556 DYVQNDDIPL 585
+++D PL
Sbjct: 99 GIKRSEDFPL 108
>UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=8; Cyanobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Prochlorococcus marinus
Length = 1182
Score = 40.7 bits (91), Expect = 0.051
Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Frame = +1
Query: 241 NTEAPHIVVLDGGFSTQL-SCHVGHVIDGDPLWSA---RFIHTHPNEVVNTHLDFLRAGA 408
N+ ++V DG T L S ++ G L + T+P V N H +L G
Sbjct: 9 NSSKSSVLVFDGAMGTSLQSLNLTADDFGGTLLEGCNENLVLTNPQAVRNVHRSYLEVGC 68
Query: 409 DLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLI 588
D+I TNT+ A+ E+ +++ YE+ A +LAK +++ +D +
Sbjct: 69 DVIETNTFGATSIVLEEY--NLQDKTYEINLEAARLAKGI-------VKEFSTDDKPRFV 119
Query: 589 VGSVGP 606
GSVGP
Sbjct: 120 AGSVGP 125
>UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9;
Saccharomycetaceae|Rep: Homocysteine S-methyltransferase
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 325
Score = 40.7 bits (91), Expect = 0.051
Identities = 41/142 (28%), Positives = 67/142 (47%), Gaps = 11/142 (7%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSA-RFI-------HTHPNEVVNTHL--DFLRAGA 408
++VLDGG T+L V +P+WS FI + N + + DFL AGA
Sbjct: 17 VLVLDGGQGTELENRGIKV--ANPVWSTIPFISESFWSDESSANRKIVKEMFNDFLNAGA 74
Query: 409 DLIITNTYQASVEGFVEHLGV-TKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPL 585
++++T TYQ S + E+ + T + L+ R V + R+ + D
Sbjct: 75 EILMTTTYQTSYKSVSENTPIRTLSEYNNLLNRIVDFS-----------RNCIGED--KY 121
Query: 586 IVGSVGPYGAHLHDGSEYDGSY 651
++G +GP+GAH+ E+ G Y
Sbjct: 122 LIGCIGPWGAHI--CREFTGDY 141
>UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=1;
Lactobacillus plantarum|Rep: Methylenetetrahydrofolate
reductase - Lactobacillus plantarum
Length = 618
Score = 40.3 bits (90), Expect = 0.068
Identities = 15/29 (51%), Positives = 22/29 (75%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQAS 441
THP+ ++ H ++RAGAD+I TNTY A+
Sbjct: 38 THPDTILRVHRSYIRAGADIIQTNTYAAN 66
>UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransferase
family protein; n=1; uncultured alpha proteobacterium
EBAC2C11|Rep: Putative homocysteine S-methyltransferase
family protein - uncultured alpha proteobacterium
EBAC2C11
Length = 309
Score = 40.3 bits (90), Expect = 0.068
Identities = 20/60 (33%), Positives = 33/60 (55%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
++LD G ST+L + +G WS ++V TH+ ++ AGAD+I N+Y +S
Sbjct: 18 IILDSGVSTELERRGAKMRNGQ--WSGCVAIDDYEKLVETHIAYIEAGADIITVNSYASS 75
>UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3;
Bacteria|Rep: Homocysteine S-methyltransferase -
Pelagibacter ubique
Length = 302
Score = 39.9 bits (89), Expect = 0.089
Identities = 22/58 (37%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = +1
Query: 265 VLDGGFSTQLSCHVGHVIDGDPLWSARFI--HTHPNEVVNTHLDFLRAGADLIITNTY 432
+LDGG +L G +G LWSA + + +++THLDF++AGA++I+T T+
Sbjct: 11 ILDGGMGQELLAR-GMKPNGT-LWSANAVLKEEYHQLLLDTHLDFIKAGAEVIVTATF 66
>UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;
Proteobacteria|Rep: Homocysteine S-methyltransferase -
Psychrobacter sp. PRwf-1
Length = 310
Score = 39.9 bits (89), Expect = 0.089
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
I ++DGG +L+ P WSA + P V + H DF+R+GA +I TN+Y
Sbjct: 6 ITIIDGGMGRELAKRGAPF--RQPEWSALAMIEAPEIVRDVHRDFIRSGAGVITTNSY-- 61
Query: 439 SVEGFVEHLGVTK--EQGYELIARAVQLAKQA 528
++ F H+G + + +L A A ++A+ A
Sbjct: 62 ALLPF--HIGEVRFAKHAQDLAASAGEMARAA 91
>UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 176
Score = 39.1 bits (87), Expect = 0.16
Identities = 37/124 (29%), Positives = 53/124 (42%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
VV DG L G+V+ G W+ +P+ V H +FLRAGAD+I T TY A+
Sbjct: 22 VVGDGSMLITLEKR-GYVMAGS--WTPEATLQYPDAVKQLHREFLRAGADVIQTFTYCAT 78
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
+ K ++ +A L E V N+ L+ GSV A+
Sbjct: 79 EDNLKMKNEHEKNSNDMKSVSVSEINHRACDLARE-----VANEGGALVAGSVSNVNAYR 133
Query: 622 HDGS 633
DG+
Sbjct: 134 KDGA 137
>UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family
protein; n=9; Rhodobacteraceae|Rep: Homocysteine
S-methyltransferase family protein - Silicibacter
pomeroyi
Length = 298
Score = 39.1 bits (87), Expect = 0.16
Identities = 30/94 (31%), Positives = 43/94 (45%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
I +LDG +L G PLWS + P V H D+ AGA + TNTY A
Sbjct: 4 ITLLDGSIGQELVKRAGK--RPTPLWSTSVMLEAPYHVGAVHRDYFDAGATIATTNTY-A 60
Query: 439 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 540
+ +E G+ ++ LI A+ A+ AR +
Sbjct: 61 VLRDRLEPAGI-GDRFEALIDTALDQAESARAAH 93
>UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Homocysteine S-methyltransferase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 411
Score = 39.1 bits (87), Expect = 0.16
Identities = 38/134 (28%), Positives = 59/134 (44%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
++V DG TQL + + LWS T P + H D+ AG+D + TNT+ A
Sbjct: 10 VLVFDGAMGTQLIQNGLKENECPDLWSV----TRPEVIAKIHRDYFEAGSDCVETNTFGA 65
Query: 439 SVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAH 618
+ E ++ G+ E ++ A+ LAK +EY YV SVGP G
Sbjct: 66 NREKLKKY-GLENEV-EKINKAAILLAKDV----AKEYGGYVGL--------SVGPTGRL 111
Query: 619 LHDGSEYDGSYADT 660
+ + D A++
Sbjct: 112 MRPSGDLDFDEAES 125
>UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1;
Desulfotomaculum reducens MI-1|Rep: Homocysteine
S-methyltransferase - Desulfotomaculum reducens MI-1
Length = 800
Score = 39.1 bits (87), Expect = 0.16
Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVE-HLGVTKEQGYELIARAVQLAKQAR 531
+HP V H +L AGAD+I TNT+ A + HLG +Q E+ AV+LAK+
Sbjct: 39 SHPEAVKEIHKLYLEAGADIITTNTFGAIQLKLADYHLG---DQVKEINQAAVKLAKEVA 95
Query: 532 TLYLEEYRDYVQNDDIPLIVGSVGPYGAHL 621
Y ++ GSVGP G L
Sbjct: 96 QPY------------GAMVAGSVGPLGKFL 113
>UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=60;
Bacilli|Rep: Methylenetetrahydrofolate reductase -
Bacillus halodurans
Length = 618
Score = 38.3 bits (85), Expect = 0.27
Identities = 21/58 (36%), Positives = 35/58 (60%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
T P ++V H+ ++ AGAD+I TNTY A+ ++ +Q E+ AV+LA++A
Sbjct: 38 TDPEKIVAAHVAYVEAGADVIQTNTYAANRMKLAKY--QLDDQVLEINRAAVRLARKA 93
>UniRef50_A5UPF4 Cluster: Methionine synthase; n=4;
Chloroflexaceae|Rep: Methionine synthase - Roseiflexus
sp. RS-1
Length = 1254
Score = 38.3 bits (85), Expect = 0.27
Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVID--GDPLWSAR--FIHTHPNEVVNTHLDFLRAGADLIITN 426
+++ DG T + D G+ + AR + T P+ + H FL AGAD++ T
Sbjct: 58 VLIYDGAMGTSIDTFHLTAADYGGENTFGARDYLVMTRPDVIEQIHTSFLEAGADVLETC 117
Query: 427 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 606
T+Q S +E G+ +Q + + A +LA++ + E RD + GS+GP
Sbjct: 118 TFQ-STRIRLEEWGLA-DQTHAINVAAARLARRVADAF--EARDGRPR----YVAGSMGP 169
Query: 607 YG 612
G
Sbjct: 170 TG 171
>UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2;
Anaeromyxobacter|Rep: Homocysteine S-methyltransferase -
Anaeromyxobacter sp. Fw109-5
Length = 280
Score = 37.9 bits (84), Expect = 0.36
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Frame = +1
Query: 247 EAPHI-VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIIT 423
EAP +LDGG T L V + L ++ P+ + H D RAGA++++T
Sbjct: 6 EAPGAPTLLDGGMGTAL---VARGLPQGAL-PEEWLLARPDAIAEVHADHARAGAEIVLT 61
Query: 424 NTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
T+ + + L + + EL A AV+LA+ A
Sbjct: 62 CTFNLAAPRLAQRLDPPRVE--ELAAIAVRLARGA 94
>UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=2; Epsilonproteobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Nitratiruptor sp. (strain SB155-2)
Length = 1148
Score = 37.9 bits (84), Expect = 0.36
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVI----DGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITN 426
I+++DG TQL + +G + T P + + H + + GAD+I TN
Sbjct: 10 ILIIDGAMGTQLQAKANEISADVWEGKEGCNELLNRTAPKVIKSIHEAYAKVGADIIKTN 69
Query: 427 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 540
T+ S+ ++ + E Y+L R +L K+ Y
Sbjct: 70 TF-GSMPWVLDEYDLASE-AYDLTKRGCELVKEVCETY 105
>UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Beggiatoa sp. PS|Rep:
5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Beggiatoa sp. PS
Length = 157
Score = 37.5 bits (83), Expect = 0.48
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
T P+ + H +L AGAD+I TNT+ A+ ++ +E YEL +LA++A
Sbjct: 58 TQPHIIKEIHTQYLEAGADIIETNTFNATRIAMADYR--MEELVYELNVAGAKLAREA 113
>UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;
Schizosaccharomyces pombe|Rep: Uncharacterized protein
C57A7.07c - Schizosaccharomyces pombe (Fission yeast)
Length = 308
Score = 37.5 bits (83), Expect = 0.48
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQA 438
+++LDGG ST + + I LW++ + +P VV H +FL+ D+I T TYQ
Sbjct: 1 MLMLDGG-STAILPKLPESISESRLWTSEALVRYPEIVVKHHEEFLKV-CDIISTFTYQL 58
Query: 439 SVEGFVEHL-GVTKEQGY 489
+ E + GV +Q Y
Sbjct: 59 DASIYDEKVEGVPLKQVY 76
>UniRef50_Q6AL45 Cluster: Related to
5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Desulfotalea psychrophila|Rep:
Related to 5-methyltetrahydrofolate--homocysteine
methyltransferase - Desulfotalea psychrophila
Length = 316
Score = 37.1 bits (82), Expect = 0.63
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 2/118 (1%)
Frame = +1
Query: 259 IVVLDGGFSTQL-SCHVGHVIDGDPLWSARFIH-THPNEVVNTHLDFLRAGADLIITNTY 432
+++ DG T L S ++ GD F++ + P ++ H FL AGA ++ TNT+
Sbjct: 8 LLIFDGACGTTLQSMNIAPSAWGDLAGCNEFLNISAPEYIIELHKKFLEAGAMVVETNTF 67
Query: 433 QASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 606
AS E+ G+ + E+ AV+ AK+A + + +D Q I GS+GP
Sbjct: 68 GASSIVLTEY-GLENKVD-EINREAVKNAKKA----ISQLKDSSQP---RYIAGSIGP 116
>UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:
Methionine synthase - Solibacter usitatus (strain
Ellin6076)
Length = 1185
Score = 36.7 bits (81), Expect = 0.83
Identities = 19/57 (33%), Positives = 33/57 (57%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQ 525
T P+ + + H +L AGAD+I TNT+ + ++ +E+ YEL A +LA++
Sbjct: 54 TRPDVIQDIHRQYLEAGADIIETNTFGGTRIALADN--KLEERAYELNFAAAKLARE 108
>UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 1231
Score = 36.7 bits (81), Expect = 0.83
Identities = 25/84 (29%), Positives = 44/84 (52%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 534
T P+ + + H +L AGAD+ TNT+ A+ +E G+ + Q + A +LA++
Sbjct: 57 TRPDVIKSIHRQYLDAGADIFATNTFNANAIS-MEDYGM-QGQVRNINLAAGKLAREVAD 114
Query: 535 LYLEEYRDYVQNDDIPLIVGSVGP 606
+++E+ D + GSVGP
Sbjct: 115 GFMKEHPDRT-----IFVAGSVGP 133
>UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=1;
Victivallis vadensis ATCC BAA-548|Rep:
Methylenetetrahydrofolate reductase - Victivallis
vadensis ATCC BAA-548
Length = 595
Score = 36.7 bits (81), Expect = 0.83
Identities = 21/59 (35%), Positives = 39/59 (66%), Gaps = 1/59 (1%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARA-VQLAKQA 528
T P+ +++ H +L+AGA+++ TNTY A+ + G++++ E I RA V+LA++A
Sbjct: 30 TAPDVILDIHHQYLKAGAEVLTTNTYNANSRRLAK-FGLSEQT--EAINRAGVKLAREA 85
>UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium falciparum (isolate 3D7)
Length = 581
Score = 35.9 bits (79), Expect = 1.5
Identities = 22/72 (30%), Positives = 40/72 (55%)
Frame = +1
Query: 376 NTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYR 555
N HL +L G ++I TNT+Q ++ F + LG+ + G E++ + + +A + Y E R
Sbjct: 47 NIHLSYLLGGCNIIGTNTFQVNLYSF-KKLGI--DNGEEILNKYINIAYNSLLKYEEIKR 103
Query: 556 DYVQNDDIPLIV 591
DDI +++
Sbjct: 104 K--SKDDINVLL 113
>UniRef50_A7RIN6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 434
Score = 35.9 bits (79), Expect = 1.5
Identities = 21/58 (36%), Positives = 31/58 (53%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 432
+++ DGG S L +V G +W+ + HP V H +FLRAGAD+I T+
Sbjct: 22 VIIGDGGMSHALEKRC-YVKIG--VWTPECVVEHPEAVRQLHSEFLRAGADVIQAFTF 76
>UniRef50_Q55786 Cluster: Methionine synthase; n=5;
Cyanobacteria|Rep: Methionine synthase - Synechocystis
sp. (strain PCC 6803)
Length = 1195
Score = 35.9 bits (79), Expect = 1.5
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +1
Query: 349 IHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAK 522
+HT P V H F AGAD++ T+T+ + E+ +Q Y L A +LAK
Sbjct: 50 VHTKPEAVATVHRAFYEAGADVVETDTFGGTPLVLAEY--DLADQSYYLNKAAAELAK 105
>UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=3; Desulfovibrio|Rep: Vitamin
B12-dependent methionine synthase family protein -
Desulfovibrio desulfuricans (strain G20)
Length = 841
Score = 35.5 bits (78), Expect = 1.9
Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +1
Query: 346 FIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQ 525
F ++P + HLD+ RAGAD++ TNT+ + E + V E E+ A A Q
Sbjct: 69 FCLSNPAVLQGVHLDYARAGADVLTTNTFGGTRLKLPEGMNVV-EFNREMARAAKAAAGQ 127
Query: 526 A-RTLYL 543
A RT+++
Sbjct: 128 AGRTVFV 134
>UniRef50_A5ZSP9 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 490
Score = 35.1 bits (77), Expect = 2.5
Identities = 27/111 (24%), Positives = 53/111 (47%)
Frame = +1
Query: 334 WSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQ 513
WS + + NE++N L G+ +++ + ++ SV+ ++ + ++GY+L+ +
Sbjct: 298 WSYKDVDKDYNEIMNGDLT---DGSIILMHDIHEPSVQAAIKMIPELVQKGYKLMTVSEL 354
Query: 514 LAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGAHLHDGSEYDGSYADTTS 666
A + TL Y D+ D L G V Y + DGS + +D T+
Sbjct: 355 AAAKGVTLQNANYSDFW---DSSLQKGIVAGYNSGSSDGSSDGTAVSDGTT 402
>UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4;
Bacteria|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 826
Score = 35.1 bits (77), Expect = 2.5
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGF 453
TH E+ H ++ AG+D+I+TNT+ A+ F
Sbjct: 38 THSEEIYKIHRQYIEAGSDIILTNTFGANALKF 70
>UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium chabaudi
Length = 504
Score = 35.1 bits (77), Expect = 2.5
Identities = 17/55 (30%), Positives = 32/55 (58%)
Frame = +1
Query: 376 NTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 540
N HL +L +G+++I TNTYQ ++ + ++ E G E+I + +A ++ Y
Sbjct: 45 NIHLSYLLSGSNIITTNTYQVNLH--FKRNNISIENGKEIIDTYIDIAYESCEKY 97
>UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Lentisphaera araneosa
HTCC2155|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Lentisphaera araneosa HTCC2155
Length = 1204
Score = 34.7 bits (76), Expect = 3.4
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 5/66 (7%)
Frame = +1
Query: 259 IVVLDG--GFSTQLSCHVGHVIDGDP--LWSARFIHTHPNEVV-NTHLDFLRAGADLIIT 423
I+VLDG G QL G+ + S + + P++V N HL++L+AGA+++ T
Sbjct: 11 ILVLDGAMGSMVQLLKLPDSAYGGEEYAMLSDLLVFSRPDQVRDNIHLEYLKAGANILET 70
Query: 424 NTYQAS 441
NT+ AS
Sbjct: 71 NTFGAS 76
>UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella
succinogenes|Rep: S-METHYLTRANSFERASE - Wolinella
succinogenes
Length = 1120
Score = 34.3 bits (75), Expect = 4.4
Identities = 18/58 (31%), Positives = 34/58 (58%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
T + +++ H +L AGAD++ +NT+ A + +E G+ + YE+ Q+AK+A
Sbjct: 48 TRGDVILSIHRSYLEAGADILKSNTFGA-LPWVLEEYGI-GGRAYEMAFAGAQIAKEA 103
>UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium
nucleatum|Rep: Methionine synthase - Fusobacterium
nucleatum subsp. polymorphum ATCC 10953
Length = 1082
Score = 34.3 bits (75), Expect = 4.4
Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFI--HTHPNEVVNTHLDFLRAGADLIITNTY 432
I+VLDG T L + D + I T P+ + H ++ AGAD+I TN++
Sbjct: 12 ILVLDGAMGTVLQKYELTPEDFNGAKGCYEILNETRPDIIFEVHKKYIEAGADIIETNSF 71
Query: 433 QASVEGFVE-HLGVTKEQGYELIARAVQLAKQA 528
+ + HL +++ Y+L ++ ++A+ A
Sbjct: 72 NCNAISLKDYHL---EDKVYDLAKKSAEIARDA 101
>UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine
methyltransferase; n=9; cellular organisms|Rep:
5-Methyltetrahydrofolate-S-homocysteine
methyltransferase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 1168
Score = 33.9 bits (74), Expect = 5.9
Identities = 24/84 (28%), Positives = 41/84 (48%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART 534
+ P V H + AGAD++ TNT+ S+ E G+ +++ E+ A LA++A
Sbjct: 50 SRPELVREIHRGYFEAGADMVETNTFGGSIVTLAE-FGL-QDRTREINRTAATLAREAAE 107
Query: 535 LYLEEYRDYVQNDDIPLIVGSVGP 606
+ + YV +GS+GP
Sbjct: 108 TFADGRHRYV--------MGSIGP 123
>UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep:
Msh - Agrobacterium tumefaciens
Length = 316
Score = 33.9 bits (74), Expect = 5.9
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTY 432
+ +LDGG +L + P WSA + P V H F+ AGA++I TN+Y
Sbjct: 5 VTILDGGMGRELLRNGAPF--RQPEWSALSLIEAPEFVKMAHDAFVAAGAEVITTNSY 60
>UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2;
Desulfitobacterium hafniense|Rep: Homocysteine
S-methyltransferase - Desulfitobacterium hafniense
(strain DCB-2)
Length = 285
Score = 33.9 bits (74), Expect = 5.9
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +1
Query: 262 VVLDGGFSTQLSCHVGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQAS 441
V+ DG T L + + G P T P + H +++AG+++I TNT+ A
Sbjct: 9 VIFDGAMGTMLQKY--DLAPGQPPEVLNI--TRPEVIEEVHRKYIKAGSNIITTNTFGA- 63
Query: 442 VEGFVEHLGVTKEQGYELIARAVQLAKQA 528
+E + G + E E++ A+ +A++A
Sbjct: 64 IETKLNGTGYSVE---EVVQSAIAIARRA 89
>UniRef50_A5Z6N8 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 393
Score = 33.9 bits (74), Expect = 5.9
Identities = 16/45 (35%), Positives = 29/45 (64%)
Frame = +1
Query: 364 NEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELI 498
N V +T L +A +++ + +Q SV+GF++ L K++GYEL+
Sbjct: 324 NYVSSTILKETKAWDIVLLHDIHQTSVDGFIKALPTLKKRGYELV 368
>UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep:
Methionine synthase - Magnetococcus sp. (strain MC-1)
Length = 1220
Score = 33.9 bits (74), Expect = 5.9
Identities = 18/58 (31%), Positives = 32/58 (55%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
T P + N H +L AGAD++ TNT+ + ++ G+ + YE+ ++A+QA
Sbjct: 63 TKPQVIRNIHTAYLEAGADIVETNTFNGNAPSLGDY-GL-EALVYEVNLEGARVARQA 118
>UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 1178
Score = 33.9 bits (74), Expect = 5.9
Identities = 17/58 (29%), Positives = 34/58 (58%)
Frame = +1
Query: 355 THPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
T P+ +++ H +L AGAD + TNT+ + ++ G+ ++ Y L + ++AK+A
Sbjct: 43 TKPDAILDIHKGYLEAGADFVETNTFSGTKIAQADY-GL-EDAAYRLNRASAEVAKRA 98
>UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associated
KRAB repressor, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to RB-associated KRAB
repressor, partial - Ornithorhynchus anatinus
Length = 395
Score = 33.5 bits (73), Expect = 7.8
Identities = 23/74 (31%), Positives = 38/74 (51%)
Frame = +1
Query: 307 GHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQG 486
G + GDP + NTH D+L AGAD+I TNT+ + ++ G+ +
Sbjct: 79 GRSLPGDPAPPTEEMKYDXXXXNNTH-DYLLAGADIIETNTFSGTRVAQADY-GL-EHLA 135
Query: 487 YELIARAVQLAKQA 528
YEL + ++A++A
Sbjct: 136 YELNRTSAEVARRA 149
>UniRef50_Q9WYA5 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=2; Thermotoga|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Thermotoga maritima
Length = 768
Score = 33.5 bits (73), Expect = 7.8
Identities = 21/79 (26%), Positives = 46/79 (58%)
Frame = +1
Query: 361 PNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 540
P+ V+ H ++ +G+D+I+TNT+ A+ +H G+ +++ ++ AV++A++A
Sbjct: 43 PDVVLKVHRSYIESGSDVILTNTFGATRMKLRKH-GL-EDKLDPIVRNAVRIARRAAGEK 100
Query: 541 LEEYRDYVQNDDIPLIVGS 597
L + D ++P +GS
Sbjct: 101 L-VFGDIGPTGELPYPLGS 118
>UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=21; Bacteria|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Bacillus halodurans
Length = 1146
Score = 33.5 bits (73), Expect = 7.8
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Frame = +1
Query: 220 MTPPSSENTEAPHIVVLDGGFSTQLSCH--VGHVIDGDPLWSAR--FIHTHPNEVVNTHL 387
MT E IV+LDG T L G+ T P+ V + H
Sbjct: 1 MTKSLFEQQLERKIVILDGAMGTMLQAANLTADDFGGEEYEGCNEYLNETAPHVVEDIHR 60
Query: 388 DFLRAGADLIITNTYQASVEGFVEH-LGVTKEQGYELIARAVQLAKQ 525
+L AGAD+I TNT+ A+ ++ LG E EL AV++AK+
Sbjct: 61 AYLEAGADVIATNTFGATDIVLDDYDLGYKAE---ELNICAVKIAKR 104
>UniRef50_Q8ESE8 Cluster: Betaine-homocysteine methyltransferase;
n=5; Bacteria|Rep: Betaine-homocysteine
methyltransferase - Oceanobacillus iheyensis
Length = 349
Score = 33.5 bits (73), Expect = 7.8
Identities = 22/65 (33%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 358 HPNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIAR-AVQLAKQART 534
+P+ + T+ DF+ AG+D+++ TY A E + +G KEQ E + R A++LAK+
Sbjct: 43 NPDALKQTYRDFMNAGSDVVLAFTYNAHREK-MRIIG--KEQLLEPLNRSAIRLAKEVAK 99
Query: 535 LYLEE 549
+ +E
Sbjct: 100 EHPQE 104
>UniRef50_Q748M7 Cluster: Methylenetetrahydrofolate reductase; n=8;
Desulfuromonadales|Rep: Methylenetetrahydrofolate
reductase - Geobacter sulfurreducens
Length = 605
Score = 33.5 bits (73), Expect = 7.8
Identities = 20/56 (35%), Positives = 34/56 (60%)
Frame = +1
Query: 361 PNEVVNTHLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 528
P+ V+ H ++L AGA +I TNT+ A+ +G+ K++ E+ R QLA++A
Sbjct: 41 PSLVLELHREYLAAGARVIETNTFGANWTRLAA-IGLEKKE-REINLRGAQLAREA 94
>UniRef50_Q0IB34 Cluster: Possible MFS family transporter, putative;
n=1; Synechococcus sp. CC9311|Rep: Possible MFS family
transporter, putative - Synechococcus sp. (strain
CC9311)
Length = 409
Score = 33.5 bits (73), Expect = 7.8
Identities = 17/53 (32%), Positives = 23/53 (43%)
Frame = -1
Query: 359 CVWIKRALHSGSPSMTCPTWQDSWVENPPSSTTMCGASVFSLLGGVIVRAFCP 201
C W L +G PS+ +W + MCG V +LLG V + F P
Sbjct: 109 CGWGAAQLVAGLPSLALERVPSNW-RRQSTGVIMCGGGVGALLGAVAIGTFSP 160
>UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:
Methionine synthase - Anaeromyxobacter sp. Fw109-5
Length = 1149
Score = 33.5 bits (73), Expect = 7.8
Identities = 33/120 (27%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Frame = +1
Query: 262 VVLDGGFSTQLSCH--VGHVIDGDPLWSARFIHTHPNEVVNTHLDFLRAGADLIITNTYQ 435
+V DG TQ+ H G + T P+ V + H + G D++ TNT+
Sbjct: 12 LVFDGAMGTQIQRHQLTAAEFGGKDGANDLLTLTRPDLVEDIHARYFAVGCDVVETNTFG 71
Query: 436 ASVEGFVEH-LGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYG 612
+S E+ LG + YE+ RA LA++A + D + GS+GP G
Sbjct: 72 SSRLKLDEYGLG---HRTYEVNFRAAILARRAA-------ERFATPDHPRFVAGSMGPTG 121
>UniRef50_A6TTI3 Cluster: Homocysteine S-methyltransferase; n=2;
Clostridiales|Rep: Homocysteine S-methyltransferase -
Alkaliphilus metalliredigens QYMF
Length = 789
Score = 33.5 bits (73), Expect = 7.8
Identities = 13/28 (46%), Positives = 19/28 (67%)
Frame = +1
Query: 358 HPNEVVNTHLDFLRAGADLIITNTYQAS 441
HP + H F+RAGA ++ TNT+QA+
Sbjct: 40 HPELIQQIHERFVRAGAQVVTTNTFQAN 67
>UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Prochlorococcus marinus str. MIT
9211|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Prochlorococcus marinus str. MIT
9211
Length = 1191
Score = 33.5 bits (73), Expect = 7.8
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
Frame = +1
Query: 259 IVVLDGGFSTQLSCHVGHVID--GDPLWSAR--FIHTHPNEVVNTHLDFLRAGADLIITN 426
I+V DGG T L D G + ++P V H +L G D+I TN
Sbjct: 13 ILVFDGGMGTALQLQELSKEDFGGSQFEGCNEYLLISNPKSVEKVHRSYLEVGCDVIETN 72
Query: 427 TYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGP 606
T+ A+ E+ G+ + + Y+L A +K A+TL ++Y + GS+GP
Sbjct: 73 TFGATSVVLAEY-GL-ENKAYQLNLAA---SKMAKTL----AKEYSTINKPRYAAGSIGP 123
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 804,785,842
Number of Sequences: 1657284
Number of extensions: 16400743
Number of successful extensions: 42996
Number of sequences better than 10.0: 103
Number of HSP's better than 10.0 without gapping: 41486
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42945
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 84441173866
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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