Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP24_F_M03
(895 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9BY41 Cluster: Histone deacetylase 8; n=40; Eumetazoa|... 235 8e-61
UniRef50_UPI0000D55D9C Cluster: PREDICTED: similar to histone de... 233 6e-60
UniRef50_UPI0000587266 Cluster: PREDICTED: similar to Histone de... 221 1e-56
UniRef50_Q17CU3 Cluster: Histone deacetylase; n=2; Aedes aegypti... 210 4e-53
UniRef50_Q13547 Cluster: Histone deacetylase 1; n=60; Fungi/Meta... 190 4e-47
UniRef50_UPI000065D235 Cluster: Histone deacetylase 1 (HD1).; n=... 190 5e-47
UniRef50_Q9HDT2 Cluster: Histone deacetylase; n=4; Fungi/Metazoa... 189 7e-47
UniRef50_Q92769 Cluster: Histone deacetylase 2; n=50; Eukaryota|... 189 7e-47
UniRef50_A3BWV6 Cluster: Putative uncharacterized protein; n=2; ... 187 3e-46
UniRef50_A3C9I4 Cluster: Putative uncharacterized protein; n=6; ... 182 1e-44
UniRef50_P53096 Cluster: Probable histone deacetylase HOS2; n=15... 182 1e-44
UniRef50_Q5KKR8 Cluster: Histone deacetylase 1-1 (Hd1), putative... 178 2e-44
UniRef50_Q5XTS3 Cluster: Histone deacetylase HDAC; n=2; Giardia ... 179 8e-44
UniRef50_O15379 Cluster: Histone deacetylase 3; n=149; Eukaryota... 176 5e-43
UniRef50_A2FDZ0 Cluster: Acetylpolyamine aminohydrolase, putativ... 175 2e-42
UniRef50_Q5U8M9 Cluster: Histone deacetylase 1; n=2; Entamoeba h... 169 8e-41
UniRef50_Q94D35 Cluster: Histone deacetylase-like; n=9; Oryza sa... 167 3e-40
UniRef50_Q4WHY0 Cluster: Histone deacetylase HosA; n=15; Fungi/M... 163 5e-39
UniRef50_Q0V6A5 Cluster: Putative uncharacterized protein; n=2; ... 162 1e-38
UniRef50_Q09440 Cluster: Putative histone deacetylase 2; n=2; Ca... 157 3e-37
UniRef50_A4VDD9 Cluster: Histone deacetylase 1, 2 ,3; n=4; Oligo... 157 4e-37
UniRef50_Q6C3Y5 Cluster: Similar to CA1453|CaHOS1 Candida albica... 157 5e-37
UniRef50_Q4QAJ4 Cluster: Histone deacetylase, putative; n=3; Lei... 156 8e-37
UniRef50_A0PAD5 Cluster: Putative uncharacterized protein; n=2; ... 154 3e-36
UniRef50_A4RK28 Cluster: Putative uncharacterized protein; n=1; ... 153 6e-36
UniRef50_A5H660 Cluster: Histone deacetylase 8; n=3; Schistosoma... 151 2e-35
UniRef50_A0DPM0 Cluster: Chromosome undetermined scaffold_59, wh... 150 5e-35
UniRef50_Q74DU3 Cluster: Histone deacetylase/AcuC/AphA family pr... 149 7e-35
UniRef50_Q59Q78 Cluster: Likely histone deacetylase Hos1p; n=2; ... 149 9e-35
UniRef50_A5DN16 Cluster: Putative uncharacterized protein; n=1; ... 148 2e-34
UniRef50_Q4QCE7 Cluster: Histone deacetylase, putative; n=7; Try... 144 4e-33
UniRef50_Q3A415 Cluster: Deacetylase; n=1; Pelobacter carbinolic... 142 8e-33
UniRef50_A0CXG2 Cluster: Chromosome undetermined scaffold_30, wh... 139 8e-32
UniRef50_O67135 Cluster: Acetoin utilization protein; n=2; Aquif... 137 4e-31
UniRef50_Q6BS96 Cluster: Similar to CA1453|CaHOS1 Candida albica... 133 7e-30
UniRef50_P39067 Cluster: Acetoin utilization protein acuC; n=25;... 131 2e-29
UniRef50_A0B926 Cluster: Histone deacetylase superfamily; n=1; M... 129 1e-28
UniRef50_Q6CVU3 Cluster: Similar to sp|Q12214 Saccharomyces cere... 128 2e-28
UniRef50_Q98RL4 Cluster: Histone deacetylase; n=1; Guillardia th... 126 6e-28
UniRef50_Q12214 Cluster: Histone deacetylase HOS1; n=2; Saccharo... 126 1e-27
UniRef50_Q0S1K3 Cluster: Possible acetoin dehydrogenase; n=3; Ba... 125 2e-27
UniRef50_Q381M6 Cluster: Histone deacetylase 2; n=4; Trypanosoma... 116 3e-26
UniRef50_Q1AX98 Cluster: Histone deacetylase superfamily; n=2; B... 120 4e-26
UniRef50_Q2S035 Cluster: Acetoin utilization protein acuC; n=4; ... 120 5e-26
UniRef50_Q981B8 Cluster: Acetylpolyamine aminohydrolase; n=4; Su... 120 5e-26
UniRef50_Q8SQN9 Cluster: HISTONE DEACETYLASE; n=1; Encephalitozo... 120 7e-26
UniRef50_Q75BA6 Cluster: ADL339Wp; n=1; Eremothecium gossypii|Re... 118 2e-25
UniRef50_A7TRW5 Cluster: Putative uncharacterized protein; n=1; ... 116 8e-25
UniRef50_A0K0A0 Cluster: Histone deacetylase superfamily; n=2; A... 114 2e-24
UniRef50_Q4P6M9 Cluster: Putative uncharacterized protein; n=1; ... 82 5e-24
UniRef50_Q97Z24 Cluster: Acetoin utilization protein; n=3; Sulfo... 110 4e-23
UniRef50_A3JH86 Cluster: Deacetylase / probable acetylpolyamine ... 109 9e-23
UniRef50_A5E4H2 Cluster: Putative uncharacterized protein; n=1; ... 109 1e-22
UniRef50_UPI00015BAE44 Cluster: histone deacetylase superfamily;... 107 4e-22
UniRef50_Q6FWB7 Cluster: Similar to sp|Q12214 Saccharomyces cere... 107 4e-22
UniRef50_UPI000050FC36 Cluster: COG0123: Deacetylases, including... 103 8e-21
UniRef50_Q2J786 Cluster: Histone deacetylase superfamily; n=13; ... 103 8e-21
UniRef50_A0IVC2 Cluster: Histone deacetylase superfamily; n=5; P... 102 1e-20
UniRef50_A1RXP5 Cluster: Histone deacetylase superfamily; n=1; T... 99 2e-19
UniRef50_Q8WUI4 Cluster: Histone deacetylase 7a; n=41; Tetrapoda... 99 2e-19
UniRef50_P64375 Cluster: Acetoin utilization protein acuC; n=15;... 99 2e-19
UniRef50_Q28M71 Cluster: Histone deacetylase superfamily; n=15; ... 98 3e-19
UniRef50_A0LGT0 Cluster: Histone deacetylase superfamily; n=1; S... 96 9e-19
UniRef50_O27262 Cluster: Uncharacterized protein MTH_1194; n=1; ... 96 1e-18
UniRef50_Q1PVG5 Cluster: Similar to histone deacetylase; n=1; Ca... 95 2e-18
UniRef50_A3J841 Cluster: Histone deacetylase family protein; n=2... 95 2e-18
UniRef50_A5D0K9 Cluster: Deacetylases; n=1; Pelotomaculum thermo... 95 3e-18
UniRef50_Q02CA3 Cluster: Histone deacetylase superfamily; n=1; S... 94 4e-18
UniRef50_Q64BV4 Cluster: Acetoin utilization protein; n=5; Archa... 94 5e-18
UniRef50_Q6KAT4 Cluster: MFLJ00062 protein; n=6; Eutheria|Rep: M... 93 9e-18
UniRef50_A6EYD2 Cluster: Histone deacetylase superfamily protein... 93 9e-18
UniRef50_Q1AYS6 Cluster: Histone deacetylase superfamily; n=1; R... 93 1e-17
UniRef50_Q4SMC8 Cluster: Chromosome 3 SCAF14553, whole genome sh... 92 2e-17
UniRef50_UPI0000E463DB Cluster: PREDICTED: similar to histone de... 91 3e-17
UniRef50_Q0YKV4 Cluster: Histone deacetylase superfamily; n=1; G... 91 3e-17
UniRef50_UPI0000E87DA7 Cluster: histone deacetylase family prote... 90 6e-17
UniRef50_Q4T0M8 Cluster: Chromosome undetermined SCAF10929, whol... 89 1e-16
UniRef50_Q1NWE2 Cluster: Histone deacetylase superfamily; n=2; d... 89 1e-16
UniRef50_Q08BS8 Cluster: Zgc:152701; n=9; Euteleostomi|Rep: Zgc:... 89 1e-16
UniRef50_Q4UB07 Cluster: Histone deacetylase family protein, put... 89 1e-16
UniRef50_Q17I08 Cluster: Histone deacetylase; n=1; Aedes aegypti... 89 1e-16
UniRef50_Q9UQL6 Cluster: Histone deacetylase 5; n=141; Eumetazoa... 89 1e-16
UniRef50_UPI000051A1DA Cluster: PREDICTED: similar to HDAC4 CG17... 89 2e-16
UniRef50_UPI000069F4DB Cluster: Histone deacetylase 7a (HD7a).; ... 89 2e-16
UniRef50_UPI000065F55A Cluster: Histone deacetylase 7a (HD7a).; ... 89 2e-16
UniRef50_Q8IR37 Cluster: CG6170-PC, isoform C; n=7; Diptera|Rep:... 88 3e-16
UniRef50_Q5KL48 Cluster: Histone deacetylase clr3, putative; n=1... 88 3e-16
UniRef50_A2AWS5 Cluster: Histone deacetylase 5; n=21; Euarchonto... 87 6e-16
UniRef50_Q015Q9 Cluster: Histone deacetylase HDA110 isoform 2; n... 86 1e-15
UniRef50_Q70I53 Cluster: Histone deacetylase-like amidohydrolase... 86 1e-15
UniRef50_UPI0000F2108C Cluster: PREDICTED: hypothetical protein;... 85 2e-15
UniRef50_Q0LS19 Cluster: Histone deacetylase superfamily; n=1; C... 85 3e-15
UniRef50_Q569T0 Cluster: MGC115178 protein; n=5; Tetrapoda|Rep: ... 84 4e-15
UniRef50_A6Q2Z0 Cluster: Acetoin utilization protein; n=1; Nitra... 84 4e-15
UniRef50_A0L9T2 Cluster: Histone deacetylase superfamily; n=3; P... 84 4e-15
UniRef50_A3CT27 Cluster: Histone deacetylase superfamily; n=2; M... 84 4e-15
UniRef50_Q8GXJ1 Cluster: Histone deacetylase 15; n=11; Magnoliop... 84 4e-15
UniRef50_O67877 Cluster: Acetoin utilization protein; n=3; Bacte... 84 5e-15
UniRef50_A3JI99 Cluster: Putative aminohydrolase; n=1; Marinobac... 83 7e-15
UniRef50_Q8I9J6 Cluster: Histone deacetylase dHDAC4 isoform b; n... 83 7e-15
UniRef50_O17323 Cluster: Histone deacetylase 4; n=3; Caenorhabdi... 83 9e-15
UniRef50_Q02A43 Cluster: Histone deacetylase superfamily; n=1; S... 83 1e-14
UniRef50_Q8TWH9 Cluster: Predicted deacetylase; n=1; Methanopyru... 83 1e-14
UniRef50_Q2FQ17 Cluster: Histone deacetylase superfamily; n=1; M... 83 1e-14
UniRef50_O30107 Cluster: Uncharacterized protein AF_0130; n=2; E... 83 1e-14
UniRef50_Q8RX28 Cluster: Histone deacetylase 5; n=4; Magnoliophy... 83 1e-14
UniRef50_UPI0000DB73BE Cluster: PREDICTED: similar to HDAC6 CG61... 82 2e-14
UniRef50_Q8F7M9 Cluster: Histone deacetylase family protein; n=4... 82 2e-14
UniRef50_Q62HN7 Cluster: Acetylpolyamine aminohydrolase; n=53; P... 82 2e-14
UniRef50_A3H8X1 Cluster: Histone deacetylase superfamily; n=1; C... 82 2e-14
UniRef50_A3ZYN7 Cluster: Acetoin utilization protein; n=3; Planc... 82 2e-14
UniRef50_A7SSG8 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 82 2e-14
UniRef50_Q9UBN7 Cluster: Histone deacetylase 6; n=38; Eutheria|R... 82 2e-14
UniRef50_UPI0001555A7F Cluster: PREDICTED: similar to histone de... 81 3e-14
UniRef50_Q5LRW9 Cluster: Acetylpolyamine aminohydrolase; n=7; Rh... 81 3e-14
UniRef50_Q2LVD3 Cluster: Histone deacetylase family protein; n=1... 81 3e-14
UniRef50_A6FY71 Cluster: Histone deacetylase superfamily protein... 81 3e-14
UniRef50_Q569C4 Cluster: Histone deacetylase 10; n=5; Mammalia|R... 81 3e-14
UniRef50_Q6AKN4 Cluster: Putative uncharacterized protein; n=1; ... 81 4e-14
UniRef50_Q12GF8 Cluster: Histone deacetylase superfamily; n=6; B... 81 4e-14
UniRef50_UPI0000D56143 Cluster: PREDICTED: similar to CG6170-PA,... 81 5e-14
UniRef50_Q6AJC0 Cluster: Putative uncharacterized protein; n=1; ... 81 5e-14
UniRef50_Q7Z8L6 Cluster: Putative histone deacetylase; n=2; Pleo... 81 5e-14
UniRef50_Q09C86 Cluster: Histone deacetylase/AcuC/AphA family pr... 80 7e-14
UniRef50_Q0W553 Cluster: Putative acetoin utilization protein; n... 80 7e-14
UniRef50_A4JTS4 Cluster: Histone deacetylase superfamily; n=3; B... 80 9e-14
UniRef50_A6LM84 Cluster: Histone deacetylase superfamily; n=1; T... 79 1e-13
UniRef50_Q17MD0 Cluster: Histone deacetylase; n=1; Aedes aegypti... 79 1e-13
UniRef50_A5DRS6 Cluster: Histone deacetylase HDA1; n=7; Saccharo... 79 1e-13
UniRef50_Q64AZ9 Cluster: Deacetylase; n=1; uncultured archaeon G... 79 1e-13
UniRef50_Q2QWU2 Cluster: Histone deacetylase family protein, exp... 79 2e-13
UniRef50_A1C5E8 Cluster: Histone deacetylase hda1; n=8; Eurotiom... 79 2e-13
UniRef50_A3DNS7 Cluster: Histone deacetylase superfamily; n=1; S... 79 2e-13
UniRef50_Q941D6 Cluster: Histone deacetylase 14; n=3; Spermatoph... 79 2e-13
UniRef50_P53973 Cluster: Histone deacetylase HDA1; n=7; Saccharo... 79 2e-13
UniRef50_Q8LRK8 Cluster: Histone deacetylase 18; n=1; Arabidopsi... 79 2e-13
UniRef50_Q7XAX9 Cluster: HDA1; n=3; Magnoliophyta|Rep: HDA1 - Ze... 78 3e-13
UniRef50_Q20296 Cluster: Histone deacetylase 6; n=4; Caenorhabdi... 78 3e-13
UniRef50_UPI00015BB127 Cluster: histone deacetylase superfamily;... 78 3e-13
UniRef50_UPI0000D561E8 Cluster: PREDICTED: similar to CG1770-PA,... 78 3e-13
UniRef50_A7HL59 Cluster: Histone deacetylase superfamily; n=1; F... 78 3e-13
UniRef50_Q57955 Cluster: Uncharacterized protein MJ0535; n=1; Me... 77 5e-13
UniRef50_P56523 Cluster: Histone deacetylase clr3; n=1; Schizosa... 77 6e-13
UniRef50_Q2IF50 Cluster: Histone deacetylase superfamily; n=1; A... 77 8e-13
UniRef50_Q0G2C9 Cluster: Putative acetylpolyamine aminohydrolase... 77 8e-13
UniRef50_Q6C4P0 Cluster: Similar to sp|P53973 Saccharomyces cere... 77 8e-13
UniRef50_A4S240 Cluster: Predicted protein; n=2; Ostreococcus|Re... 76 1e-12
UniRef50_Q1DTF8 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12
UniRef50_Q8RAS9 Cluster: Deacetylases, including yeast histone d... 75 2e-12
UniRef50_UPI0000F2E91A Cluster: PREDICTED: similar to histone de... 75 2e-12
UniRef50_Q63YT0 Cluster: Histone deacetylase family protein; n=1... 75 2e-12
UniRef50_Q4PCR1 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_Q9HSP7 Cluster: Acetoin utilization protein; n=5; Halob... 75 2e-12
UniRef50_Q7ZYF0 Cluster: Hdac6-prov protein; n=2; Xenopus|Rep: H... 75 3e-12
UniRef50_Q30PJ4 Cluster: Histone deacetylase superfamily; n=1; T... 75 3e-12
UniRef50_A4YNH4 Cluster: Acetylpolyamine aminohydrolase; n=15; P... 75 3e-12
UniRef50_Q1MQQ3 Cluster: Deacetylases, including yeast histone d... 74 4e-12
UniRef50_A6G5J4 Cluster: Histone deacetylase superfamily protein... 74 6e-12
UniRef50_UPI0000F1E289 Cluster: PREDICTED: hypothetical protein;... 73 1e-11
UniRef50_Q803K0 Cluster: Zgc:55652; n=4; Danio rerio|Rep: Zgc:55... 73 1e-11
UniRef50_A1ID65 Cluster: Histone deacetylase family protein; n=1... 73 1e-11
UniRef50_Q23M98 Cluster: Histone deacetylase family protein; n=1... 73 1e-11
UniRef50_Q969S8 Cluster: Histone deacetylase 10; n=20; Euteleost... 73 1e-11
UniRef50_Q4FNF7 Cluster: Histone deacetylase family protein; n=5... 72 2e-11
UniRef50_Q987Q0 Cluster: Acetylpolyamine aminohydrolase; n=1; Me... 71 3e-11
UniRef50_Q0LE47 Cluster: Histone deacetylase superfamily; n=1; H... 71 3e-11
UniRef50_Q94EJ2 Cluster: Histone deacetylase 8; n=14; Magnolioph... 71 3e-11
UniRef50_Q8D858 Cluster: Histone deacetylase/AcuC/AphA family pr... 71 4e-11
UniRef50_A5UY48 Cluster: Histone deacetylase superfamily; n=4; C... 71 4e-11
UniRef50_Q9YG09 Cluster: Putative uncharacterized protein; n=1; ... 71 4e-11
UniRef50_Q3SA60 Cluster: Deacetylase; n=1; uncultured euryarchae... 71 4e-11
UniRef50_Q985Y7 Cluster: Mlr7469 protein; n=13; Alphaproteobacte... 71 5e-11
UniRef50_Q8F254 Cluster: Histone deacetylase family protein; n=4... 69 2e-10
UniRef50_Q31EP6 Cluster: Histone deacetylase family protein prec... 69 2e-10
UniRef50_A1I9M7 Cluster: Histone deacetylase superfamily; n=1; C... 69 2e-10
UniRef50_Q8WZR5 Cluster: Related to histone deacetylase A; n=4; ... 69 2e-10
UniRef50_Q2S0V9 Cluster: Histone deacetylase/AcuC/AphA family pr... 68 4e-10
UniRef50_A0C8R8 Cluster: Chromosome undetermined scaffold_159, w... 68 4e-10
UniRef50_Q1IJP8 Cluster: Histone deacetylase superfamily; n=1; A... 67 5e-10
UniRef50_A6SGS8 Cluster: Putative uncharacterized protein; n=3; ... 67 5e-10
UniRef50_Q57ET7 Cluster: Histone deacetylase family protein; n=3... 67 7e-10
UniRef50_Q8TLY4 Cluster: Histone deacetylase; n=3; cellular orga... 67 7e-10
UniRef50_Q604Q2 Cluster: Histone deacetylase/AcuC/AphA family pr... 66 9e-10
UniRef50_A3K7Q8 Cluster: Acetylpolyamine aminohydrolase; n=1; Sa... 66 9e-10
UniRef50_Q4RSK1 Cluster: Chromosome 13 SCAF15000, whole genome s... 66 1e-09
UniRef50_Q5LQF5 Cluster: Histone deacetylase/AcuC/AphA family pr... 66 1e-09
UniRef50_A0DIS2 Cluster: Chromosome undetermined scaffold_52, wh... 66 1e-09
UniRef50_Q8ZU23 Cluster: Acetylpolyamine aminohydrolase, putativ... 66 1e-09
UniRef50_Q48935 Cluster: Acetylpolyamine aminohydrolase; n=32; P... 66 1e-09
UniRef50_Q5QWS4 Cluster: Histone deacetylase/AcuC/AphA family pr... 66 2e-09
UniRef50_A5UZV6 Cluster: Histone deacetylase superfamily; n=5; B... 66 2e-09
UniRef50_Q00U49 Cluster: Histone deacetylase superfamily; n=3; O... 66 2e-09
UniRef50_Q9A2B7 Cluster: Histone deacetylase family protein; n=9... 65 3e-09
UniRef50_A5UTM3 Cluster: Histone deacetylase superfamily; n=4; B... 65 3e-09
UniRef50_UPI000065FABE Cluster: Histone deacetylase 6 (HD6).; n=... 64 3e-09
UniRef50_Q54X15 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_Q5K8L3 Cluster: Histone deacetylase 3, putative; n=2; F... 64 3e-09
UniRef50_Q981D8 Cluster: Deacetylase, putative; n=3; Sulfolobus|... 64 3e-09
UniRef50_A0KLZ2 Cluster: Histone deacetylase/AcuC/AphA family pr... 64 6e-09
UniRef50_A0B6D0 Cluster: Histone deacetylase superfamily; n=1; M... 64 6e-09
UniRef50_P28606 Cluster: Uncharacterized 34.1 kDa protein in gln... 64 6e-09
UniRef50_Q8EFZ9 Cluster: Histone deacetylase/AcuC/AphA family pr... 63 8e-09
UniRef50_Q3IF01 Cluster: Putative histone deacetylase family pro... 63 8e-09
UniRef50_Q12A19 Cluster: Histone deacetylase superfamily; n=4; P... 63 8e-09
UniRef50_Q4TFH7 Cluster: Chromosome undetermined SCAF4471, whole... 63 1e-08
UniRef50_A1U7D4 Cluster: Histone deacetylase superfamily; n=5; P... 63 1e-08
UniRef50_Q22CW6 Cluster: Histone deacetylase family protein; n=1... 63 1e-08
UniRef50_Q0M412 Cluster: Histone deacetylase superfamily; n=1; C... 62 1e-08
UniRef50_A1G0Y5 Cluster: Histone deacetylase superfamily precurs... 62 1e-08
UniRef50_Q8U2L6 Cluster: Aminohydrolase; n=4; Thermococcaceae|Re... 62 1e-08
UniRef50_A6T202 Cluster: Histone deacetylase superfamily protein... 62 2e-08
UniRef50_A0G5H0 Cluster: Histone deacetylase superfamily; n=9; P... 62 2e-08
UniRef50_A6ND61 Cluster: Uncharacterized protein HDAC8; n=3; Sim... 62 2e-08
UniRef50_Q9RW36 Cluster: Histone deacetylase/AcuC/AphA family pr... 61 3e-08
UniRef50_Q2SC27 Cluster: Deacetylases, including yeast histone d... 61 4e-08
UniRef50_A2BL29 Cluster: Predicted Histone deacetylase; n=1; Hyp... 61 4e-08
UniRef50_Q96DB2 Cluster: Histone deacetylase 11; n=22; Eumetazoa... 61 4e-08
UniRef50_Q7NRU4 Cluster: Histone deacetylase; n=54; Proteobacter... 60 6e-08
UniRef50_A5WHG1 Cluster: Histone deacetylase superfamily; n=17; ... 60 6e-08
UniRef50_Q7VZF1 Cluster: Histone deacetylase family protein; n=6... 60 7e-08
UniRef50_Q7U7V3 Cluster: Putative histone deacetylase/AcuC/AphA ... 60 7e-08
UniRef50_Q128P1 Cluster: Histone deacetylase superfamily; n=16; ... 60 1e-07
UniRef50_Q586J9 Cluster: Histone deacetylase, putative; n=1; Try... 48 1e-07
UniRef50_Q1VK67 Cluster: Histone deacetylase family protein; n=1... 58 2e-07
UniRef50_Q3ZWU5 Cluster: Histone deacetylase family protein; n=3... 58 3e-07
UniRef50_Q18477 Cluster: Putative uncharacterized protein; n=2; ... 58 3e-07
UniRef50_Q944K3 Cluster: Histone deacetylase 2; n=7; Magnoliophy... 58 3e-07
UniRef50_Q31HC2 Cluster: Histone deacetylase family protein; n=1... 58 4e-07
UniRef50_Q7RB89 Cluster: Histone deacetylase/AcuC/AphA family pr... 58 4e-07
UniRef50_A5W9E9 Cluster: Histone deacetylase superfamily; n=17; ... 57 5e-07
UniRef50_A3EUN7 Cluster: Histone deacetylase family protein; n=1... 57 5e-07
UniRef50_O27994 Cluster: Acetylpolyamine aminohydrolase, putativ... 57 5e-07
UniRef50_A4C9H1 Cluster: Putative histone deacetylase family pro... 57 7e-07
UniRef50_A3W9J6 Cluster: Histone deacetylase superfamily protein... 57 7e-07
UniRef50_A6VSZ5 Cluster: Histone deacetylase superfamily; n=4; G... 56 9e-07
UniRef50_Q00UC4 Cluster: Histone deacetylase superfamily; n=2; O... 56 9e-07
UniRef50_Q7R8P2 Cluster: Histone deacetylase family, putative; n... 56 9e-07
UniRef50_Q5C2D1 Cluster: SJCHGC03352 protein; n=1; Schistosoma j... 56 9e-07
UniRef50_Q4YUE6 Cluster: Putative uncharacterized protein; n=3; ... 56 9e-07
UniRef50_A6C2D6 Cluster: Deacetylase; n=1; Planctomyces maris DS... 56 2e-06
UniRef50_Q15WQ0 Cluster: Histone deacetylase superfamily; n=3; G... 55 2e-06
UniRef50_A0Y3M1 Cluster: Histone deacetylase family protein; n=1... 55 2e-06
UniRef50_Q1N4R7 Cluster: Deacetylases, including yeast histone d... 55 3e-06
UniRef50_Q1IMW0 Cluster: Histone deacetylase superfamily; n=2; A... 55 3e-06
UniRef50_A6GQW9 Cluster: Histone deacetylase family protein; n=1... 55 3e-06
UniRef50_A5K7A1 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_Q4CZ55 Cluster: Histone deacetylase, putative; n=2; Try... 54 5e-06
UniRef50_P72702 Cluster: Uncharacterized protein slr0245; n=15; ... 54 5e-06
UniRef50_Q194I2 Cluster: Histone deacetylase superfamily; n=2; D... 54 6e-06
UniRef50_A6VZD7 Cluster: Histone deacetylase superfamily; n=2; M... 54 6e-06
UniRef50_Q1H193 Cluster: Histone deacetylase superfamily; n=2; B... 53 9e-06
UniRef50_A3VQ74 Cluster: Probable histone deacetylase/AcuC/AphA ... 53 9e-06
UniRef50_A0Z891 Cluster: Deacetylases, including yeast histone d... 53 1e-05
UniRef50_A4AX75 Cluster: Histone deacetylase/AcuC/AphA family pr... 52 2e-05
UniRef50_Q0AUZ2 Cluster: Deacetylase family protrein; n=2; Clost... 52 3e-05
UniRef50_A7HFZ2 Cluster: Histone deacetylase superfamily; n=4; C... 52 3e-05
UniRef50_Q8IJW3 Cluster: Putative uncharacterized protein; n=3; ... 52 3e-05
UniRef50_A5VD94 Cluster: Histone deacetylase superfamily; n=6; A... 51 5e-05
UniRef50_A4BSQ6 Cluster: Histone deacetylase/AcuC/AphA family pr... 51 5e-05
UniRef50_Q9U266 Cluster: Putative uncharacterized protein hda-6;... 51 5e-05
UniRef50_A5GUP9 Cluster: Histone deacetylase family protein; n=1... 50 6e-05
UniRef50_Q54VQ7 Cluster: Putative uncharacterized protein; n=2; ... 50 6e-05
UniRef50_Q9VC26 Cluster: CG31119-PA; n=5; Diptera|Rep: CG31119-P... 50 1e-04
UniRef50_Q4QBZ5 Cluster: Histone deacetylase, putative; n=3; Lei... 49 2e-04
UniRef50_A5AUM3 Cluster: Putative uncharacterized protein; n=2; ... 48 2e-04
UniRef50_Q8I4I9 Cluster: Putative uncharacterized protein; n=4; ... 48 3e-04
UniRef50_Q02959 Cluster: Histone deacetylase HOS3; n=6; Saccharo... 48 3e-04
UniRef50_A3JCC1 Cluster: Deacetylases, including yeast histone d... 48 4e-04
UniRef50_A4BCK9 Cluster: Deacetylase, including yeast histone de... 47 6e-04
UniRef50_Q676B0 Cluster: Histone deacetylase 7A-like protein; n=... 47 6e-04
UniRef50_O28982 Cluster: Acetoin utilization protein, putative; ... 47 7e-04
UniRef50_Q4P2D6 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q5AF34 Cluster: Likely histone deacetylase Hos3p; n=5; ... 46 0.001
UniRef50_Q6CGA7 Cluster: Similar to sp|Q02959 Saccharomyces cere... 45 0.003
UniRef50_Q5KNI3 Cluster: Histone deacetylase, putative; n=2; Fil... 45 0.003
UniRef50_Q3U4U4 Cluster: 2 days neonate thymus thymic cells cDNA... 44 0.004
UniRef50_Q9K0J2 Cluster: Histone deacetylase family protein; n=4... 44 0.004
UniRef50_Q4WE71 Cluster: Histone deacetylase HdaA; n=1; Aspergil... 44 0.005
UniRef50_A5E451 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005
UniRef50_A0LFA3 Cluster: Histone deacetylase superfamily; n=3; D... 43 0.009
UniRef50_A5K337 Cluster: Histone deactylase, putative; n=4; Plas... 42 0.021
UniRef50_Q4W9N7 Cluster: Histone deacetylase HosB; n=3; Trichoco... 42 0.021
UniRef50_Q7Z8L8 Cluster: Putative HOS3-like histone deacetylase;... 42 0.028
UniRef50_Q74MV2 Cluster: NEQ538; n=1; Nanoarchaeum equitans|Rep:... 42 0.028
UniRef50_Q8IKB6 Cluster: Histone deacetylase, putative; n=4; Alv... 41 0.037
UniRef50_A2R2F5 Cluster: Remark: N-terminal truncated orf due to... 41 0.037
UniRef50_UPI000023CBFE Cluster: hypothetical protein FG05636.1; ... 41 0.049
UniRef50_A1ZSA9 Cluster: Histone deacetylase family protein, put... 40 0.065
UniRef50_Q4QI60 Cluster: Histone deacetylase, putative; n=3; Lei... 40 0.065
UniRef50_Q7S8C9 Cluster: Putative uncharacterized protein NCU070... 40 0.065
UniRef50_Q2H2N4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.086
UniRef50_Q1DM14 Cluster: Putative uncharacterized protein; n=1; ... 40 0.086
UniRef50_Q10IB7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.15
UniRef50_Q012I9 Cluster: FOG: Ankyrin repeat; n=3; Ostreococcus|... 39 0.20
UniRef50_A2WM81 Cluster: Putative uncharacterized protein; n=1; ... 39 0.20
UniRef50_A6RSL3 Cluster: Putative uncharacterized protein; n=2; ... 39 0.20
UniRef50_A4QWC2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.20
UniRef50_A4S2N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 38 0.46
UniRef50_Q232Y2 Cluster: Histone deacetylase family protein; n=1... 38 0.46
UniRef50_A6GUY6 Cluster: Deacetylase, histone deacetylase family... 37 0.80
UniRef50_O88895-2 Cluster: Isoform Short of O88895 ; n=6; Eutele... 36 1.4
UniRef50_Q5CPX0 Cluster: Histone deactylase of possible bacteria... 36 1.8
UniRef50_Q4UBL2 Cluster: Histone deacetylase family protein, put... 35 2.4
UniRef50_Q9YCH2 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_A7AVF1 Cluster: Histone deacetylase, putative; n=1; Bab... 35 3.2
UniRef50_UPI0000E1FBE4 Cluster: PREDICTED: hypothetical protein;... 34 5.6
UniRef50_Q744Z8 Cluster: Putative uncharacterized protein; n=2; ... 33 9.8
UniRef50_Q9XWB6 Cluster: Putative uncharacterized protein srw-1;... 33 9.8
UniRef50_A2R705 Cluster: Contig An16c0070, complete genome; n=2;... 33 9.8
>UniRef50_Q9BY41 Cluster: Histone deacetylase 8; n=40;
Eumetazoa|Rep: Histone deacetylase 8 - Homo sapiens
(Human)
Length = 377
Score = 235 bits (576), Expect = 8e-61
Identities = 99/216 (45%), Positives = 145/216 (67%)
Frame = +1
Query: 235 YLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
Y++ + V C L + RA +VH+LIEAY L ++++++ AS E++ FH+D YL+
Sbjct: 18 YIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQ 77
Query: 415 HLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI 594
HL++++ DD + +G+GYDCP +F+ + I G ++TAA+CL G+ +AI
Sbjct: 78 HLQKVSQEGDD--DHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135
Query: 595 NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSV 774
NW GGWHHA + A GFCY+ND V+ I +L+ KF+ ILYVDLD+HHG+GV+DA+ T V
Sbjct: 136 NWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKV 195
Query: 775 YTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T+S HKF PGF+PGTG + D+G G G YS N P+
Sbjct: 196 MTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPI 231
>UniRef50_UPI0000D55D9C Cluster: PREDICTED: similar to histone
deacetylase 8; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to histone deacetylase 8 - Tribolium castaneum
Length = 376
Score = 233 bits (569), Expect = 6e-60
Identities = 103/220 (46%), Positives = 152/220 (69%), Gaps = 2/220 (0%)
Frame = +1
Query: 226 RVAYLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKV--IRSSPASYEDLNVFHS 399
+V Y++ +KL +EC RLP + RA +V +LI +Y ++ KV ++S A+ ++L +FHS
Sbjct: 6 KVVYIYGDKLRRECDRLPTMLNRASIVQDLINSYRILCSDKVLTVQSRDATEDELKLFHS 65
Query: 400 DLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI 579
Y+ LK++ ++D+ + + + FG+GYDCP + + ++ + TIAGGS+TAAK L
Sbjct: 66 SSYINFLKKVNNLDNFEDYDEEQQEFGLGYDCPILEHNYDFIKTIAGGSITAAKILCKTD 125
Query: 580 ADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYW 759
+ INW GGWHHA + A GFCYVNDIV+AI+KL KF ILY+DLD+HHG+GVQ+A+
Sbjct: 126 YKVVINWFGGWHHAQRDSAAGFCYVNDIVLAIQKLTEKFTKILYLDLDIHHGDGVQNAFE 185
Query: 760 TTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFP 879
++ + TLS+HK PGFYPGTG + DIG G+ +S N P
Sbjct: 186 LSKKILTLSYHKQAPGFYPGTGLLGDIGALKGKYFSINVP 225
>UniRef50_UPI0000587266 Cluster: PREDICTED: similar to Histone
deacetylase 8; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Histone deacetylase 8 -
Strongylocentrotus purpuratus
Length = 654
Score = 221 bits (541), Expect = 1e-56
Identities = 100/221 (45%), Positives = 144/221 (65%)
Frame = +1
Query: 220 NARVAYLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHS 399
N + Y++++KL++ C ++P + RA +VH LIEAY L+ + + A+ ++L FHS
Sbjct: 288 NNEIYYVFNQKLLQLCDQVPKIPKRASMVHTLIEAYDLLDHVTPVSPEFATKDELLTFHS 347
Query: 400 DLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI 579
Y+E L+++ +D + FG+GYDCP +P +++ V +AG S++ AK L
Sbjct: 348 QEYIEFLERVNLEEDSEKDEELKQQFGLGYDCPSLPLVYDFVRLVAGASLSCAKALIQQK 407
Query: 580 ADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYW 759
IAINW GGWHHA + A GFCYVNDIV+AI KLK F +LYVDLD+HHG+ V DA+
Sbjct: 408 CRIAINWNGGWHHARRDEAAGFCYVNDIVLAILKLKEHFNRVLYVDLDLHHGDAVDDAFI 467
Query: 760 TTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T V T+S HKF PGF+PGTGS+ +G G G+ Y+ + PL
Sbjct: 468 FTPKVMTVSLHKFSPGFFPGTGSLNRVGGGRGKFYTISVPL 508
>UniRef50_Q17CU3 Cluster: Histone deacetylase; n=2; Aedes
aegypti|Rep: Histone deacetylase - Aedes aegypti
(Yellowfever mosquito)
Length = 355
Score = 210 bits (513), Expect = 4e-53
Identities = 95/204 (46%), Positives = 138/204 (67%)
Frame = +1
Query: 268 IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDD 447
++L A+ R+ +V L+ +Y L+ KVI + EDL FHS Y+E LK+ + DD
Sbjct: 2 LKLGAIGNRSAVVDELVRSYDLLQFCKVISPKRGTLEDLLSFHSSDYVECLKRYNNEDDI 61
Query: 448 YISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHN 627
+ + FG+ YDCP + +++ VS++ G +++A + G A IAINW GGWHHA
Sbjct: 62 EEVTDELQEFGLAYDCPMIEKVYDFVSSVVGSTLSAVDAILEG-ASIAINWHGGWHHAQR 120
Query: 628 NRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG 807
++A GFCYVNDIVI I KL+ KF+ +LY+DLDVHHG+GV+DA+ ++ V T+SFH+ EPG
Sbjct: 121 DKAAGFCYVNDIVIGIHKLRTKFQKVLYLDLDVHHGDGVEDAFSFSKYVMTVSFHQHEPG 180
Query: 808 FYPGTGSIEDIGCGDGEGYSCNFP 879
++PGTGS +IG G G+GY+ N P
Sbjct: 181 YFPGTGSASNIGFGAGKGYTVNAP 204
>UniRef50_Q13547 Cluster: Histone deacetylase 1; n=60; Fungi/Metazoa
group|Rep: Histone deacetylase 1 - Homo sapiens (Human)
Length = 482
Score = 190 bits (463), Expect = 4e-47
Identities = 87/197 (44%), Positives = 127/197 (64%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV +A L DIA+NW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>UniRef50_UPI000065D235 Cluster: Histone deacetylase 1 (HD1).; n=1;
Takifugu rubripes|Rep: Histone deacetylase 1 (HD1). -
Takifugu rubripes
Length = 460
Score = 190 bits (462), Expect = 5e-47
Identities = 88/197 (44%), Positives = 126/197 (63%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL ++++ R AS E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRRMEIYRPHKASGEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV A L DIAINW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>UniRef50_Q9HDT2 Cluster: Histone deacetylase; n=4; Fungi/Metazoa
group|Rep: Histone deacetylase - Ustilago maydis (Smut
fungus)
Length = 566
Score = 189 bits (461), Expect = 7e-47
Identities = 88/197 (44%), Positives = 124/197 (62%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+ ++R A+ + + FH+D Y++ L ++T ++N +
Sbjct: 18 RMRMTHNLVTNYGLHKKMDILRPKRATRDQMTRFHTDEYVDFLHRVTPETVHELTN-EGT 76
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
+ IG DCP ++E S AGGS+ AA L G +D+AINW GG HHA A GFCY
Sbjct: 77 RYLIGEDCPAFDGLYEFCSISAGGSLAAATRLNSGESDVAINWAGGLHHAKKREASGFCY 136
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L +LY+D+D+HHG+GV++A++TT V T SFHKF F+PGTG +
Sbjct: 137 VNDIVLAILELLRVHLRVLYIDIDIHHGDGVEEAFYTTDRVMTASFHKF-GDFFPGTGDV 195
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G+ Y N PL
Sbjct: 196 RDIGMKKGKNYCVNVPL 212
>UniRef50_Q92769 Cluster: Histone deacetylase 2; n=50;
Eukaryota|Rep: Histone deacetylase 2 - Homo sapiens
(Human)
Length = 488
Score = 189 bits (461), Expect = 7e-47
Identities = 86/197 (43%), Positives = 126/197 (63%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 35 RIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRP-DNMSEYSKQMQ 93
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV A L D+A+NW GG HHA + A GFCY
Sbjct: 94 RFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCY 153
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 154 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 212
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ NFP+
Sbjct: 213 RDIGAGKGKYYAVNFPM 229
>UniRef50_A3BWV6 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 384
Score = 187 bits (456), Expect = 3e-46
Identities = 91/198 (45%), Positives = 122/198 (61%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ H+L+ YGL L++ R PAS D+ FHSD Y+ L T + + +
Sbjct: 47 RIRMAHSLVVHYGLHRLLELSRPYPASDADIRRFHSDDYVAFLASATG-NPALLDARAVK 105
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +F AGGS+ AA L G ADI +NW GG HHA A GFCY
Sbjct: 106 RFNVGEDCPVFDGLFPFCQASAGGSIGAAVKLNRGDADITVNWAGGLHHAKKGEASGFCY 165
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LYVD+DVHHG+GV++A++TT V T SFHK+ F+PGTG I
Sbjct: 166 VNDIVLAILELLKFHRRVLYVDIDVHHGDGVEEAFFTTNRVMTCSFHKY-GDFFPGTGHI 224
Query: 832 EDIGCGDGEGYSCNFPLN 885
D+G G+G+ Y+ N PL+
Sbjct: 225 TDVGAGEGKHYALNVPLS 242
>UniRef50_A3C9I4 Cluster: Putative uncharacterized protein; n=6;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 449
Score = 182 bits (443), Expect = 1e-44
Identities = 86/205 (41%), Positives = 130/205 (63%), Gaps = 10/205 (4%)
Frame = +1
Query: 301 LVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITD---IDDDYISNAQDE 471
+ H+L+ YG++ + +R+ PA+ ++ FHS Y++ L+ +T +D + ++
Sbjct: 1 MAHSLVGVYGMLGDMSRLRTRPATEAEIRRFHSPEYVDLLRDLTPESYFNDAALRQKAED 60
Query: 472 NFGIGY--DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGF 645
+ GIG DCP +++ AGGS+ AA+ L G +DIAINW GG HHA +A GF
Sbjct: 61 DHGIGGKDDCPAFDRLWKYCRGYAGGSLAAARALVDGASDIAINWSGGMHHASACKATGF 120
Query: 646 CYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKF-----EPGF 810
CYVNDIV+AI +L G F+ ++YVD+D HHG+GVQ+A+ + V TLSFH++ F
Sbjct: 121 CYVNDIVLAINELLGTFRRVIYVDIDAHHGDGVQNAFLDSNRVMTLSFHRYGKITPHKNF 180
Query: 811 YPGTGSIEDIGCGDGEGYSCNFPLN 885
+PG+G+I +IG G GE YS N PL+
Sbjct: 181 FPGSGAINEIGAGAGEHYSVNVPLD 205
>UniRef50_P53096 Cluster: Probable histone deacetylase HOS2; n=15;
Dikarya|Rep: Probable histone deacetylase HOS2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 452
Score = 182 bits (442), Expect = 1e-44
Identities = 87/221 (39%), Positives = 134/221 (60%), Gaps = 2/221 (0%)
Frame = +1
Query: 226 RVAYLWDEKL--VKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHS 399
RV+Y ++ K+ ++ P R L +L+ +YGL + + + A+ ++L FHS
Sbjct: 27 RVSYHFNSKVSHYHYGVKHPMKPFRLMLTDHLVSSYGLHKIMDLYETRSATRDELLQFHS 86
Query: 400 DLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI 579
+ Y+ L +++ + + + ENF IG DCP N+++ + G S+ A + L
Sbjct: 87 EDYVNFLSKVSPENANKLPRGTLENFNIGDDCPIFQNLYDYTTLYTGASLDATRKLINNQ 146
Query: 580 ADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYW 759
+DIAINW GG HHA N GFCYVNDIV++I L ILY+D+D+HHG+GVQ+A++
Sbjct: 147 SDIAINWSGGLHHAKKNSPSGFCYVNDIVLSILNLLRYHPRILYIDIDLHHGDGVQEAFY 206
Query: 760 TTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
TT V+TLSFHK+ F+PGTG + +IGC G+ ++ N PL
Sbjct: 207 TTDRVFTLSFHKYNGEFFPGTGDLTEIGCDKGKHFALNVPL 247
>UniRef50_Q5KKR8 Cluster: Histone deacetylase 1-1 (Hd1), putative;
n=3; Filobasidiella neoformans|Rep: Histone deacetylase
1-1 (Hd1), putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 659
Score = 178 bits (434), Expect(2) = 2e-44
Identities = 83/181 (45%), Positives = 118/181 (65%)
Frame = +1
Query: 340 KLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFE 519
++++ R A+ D+ FH+D Y+E L+ + + D ++ + G DCP V +FE
Sbjct: 98 RMQIFRPRRATKTDMTRFHTDEYIELLESVLPENADALTGNRSRGL-TGSDCPAVEGIFE 156
Query: 520 LVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK 699
S AGGS+ AA+ L GIADIAINW GG HHA A GFCYVNDIV+ I +L
Sbjct: 157 FSSISAGGSIGAAEKLNEGIADIAINWAGGLHHAKKTEASGFCYVNDIVLGILELLRVNS 216
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFP 879
+LY+D+DVHHG+GV++A+++T V T SFH F F+PGTG+++D+G G G+GY+ N P
Sbjct: 217 RVLYIDIDVHHGDGVEEAFYSTDRVMTCSFHLF-GNFFPGTGTLKDVGLGKGKGYAVNVP 275
Query: 880 L 882
L
Sbjct: 276 L 276
Score = 24.6 bits (51), Expect(2) = 2e-44
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
Frame = +1
Query: 226 RVAYLWDEKLVKECIRL--PAVFGRARLVHNLIEAYGL 333
RVAY +D + L P R R+ HNL+ YGL
Sbjct: 21 RVAYYYDHDVGNYHFGLGHPMKPHRIRMTHNLVVNYGL 58
>UniRef50_Q5XTS3 Cluster: Histone deacetylase HDAC; n=2; Giardia
intestinalis|Rep: Histone deacetylase HDAC - Giardia
lamblia (Giardia intestinalis)
Length = 467
Score = 179 bits (436), Expect = 8e-44
Identities = 84/199 (42%), Positives = 124/199 (62%), Gaps = 2/199 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD- 468
R LV+ LI AYGL L A+++D+ ++H+ Y+ LK IT + +S QD
Sbjct: 29 RIALVNELILAYGLDEHLNYYTPRDATFQDMALYHTPDYIRFLKNITP---ETLSKFQDL 85
Query: 469 -ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGF 645
+ + I DCP +++ S G SV A L G+ D+A+NW GG+HHA + A GF
Sbjct: 86 AKRYNITEDCPVFSGLYDYCSMTVGASVNACAHLNHGMCDVALNWMGGFHHAKASEASGF 145
Query: 646 CYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTG 825
CY ND+V+ I +L + +LYVD+D+H G+GV++A++TT V TLSFHK++ F+PGTG
Sbjct: 146 CYANDLVLGILELLKVHERVLYVDIDIHAGDGVEEAFYTTNRVLTLSFHKYDTDFFPGTG 205
Query: 826 SIEDIGCGDGEGYSCNFPL 882
++ D G G+GY+ NFPL
Sbjct: 206 NLFDNGADQGKGYAINFPL 224
>UniRef50_O15379 Cluster: Histone deacetylase 3; n=149;
Eukaryota|Rep: Histone deacetylase 3 - Homo sapiens
(Human)
Length = 428
Score = 176 bits (429), Expect = 5e-43
Identities = 84/197 (42%), Positives = 118/197 (59%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L H+L+ YGL K+ V + AS D+ FHS+ Y++ L++++ + + + +
Sbjct: 28 RLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNA 87
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP P +FE S G S+ A L I DIAINW GG HHA A GFCY
Sbjct: 88 -FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCY 146
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIVI I +L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG +
Sbjct: 147 VNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDM 206
Query: 832 EDIGCGDGEGYSCNFPL 882
++G G Y N PL
Sbjct: 207 YEVGAESGRYYCLNVPL 223
>UniRef50_A2FDZ0 Cluster: Acetylpolyamine aminohydrolase, putative;
n=1; Trichomonas vaginalis G3|Rep: Acetylpolyamine
aminohydrolase, putative - Trichomonas vaginalis G3
Length = 453
Score = 175 bits (425), Expect = 2e-42
Identities = 84/221 (38%), Positives = 130/221 (58%), Gaps = 2/221 (0%)
Frame = +1
Query: 226 RVAYLWDEKLVKECIRL--PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHS 399
R+AY +DE + P R R+ H+L+ Y L + V AS E++ FH+
Sbjct: 7 RIAYFYDEDIGNYYYTHSHPMKPVRVRMTHSLVLGYKLHEHMDVFHPRRASPEEMMRFHT 66
Query: 400 DLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI 579
Y++ L+ T + + S ++ IG+DCP N+FE AGGS++AA+ L +
Sbjct: 67 PGYIKFLQTATPSNTNPKSE-DAVHYNIGFDCPVFDNIFEFCQISAGGSISAAQRLNYNL 125
Query: 580 ADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYW 759
AD+AINW GG HHA ++A GFCY+ D V+ I +L ++Y+D+D+HHG+GV++A++
Sbjct: 126 ADVAINWAGGLHHARRDQASGFCYIADCVLGIMELLKYHPRVMYIDIDIHHGDGVEEAFY 185
Query: 760 TTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T V T+SFHK+ F+P +G I D+G G+ Y+ N PL
Sbjct: 186 NTDRVLTVSFHKYGKEFFPESGHISDVGINSGKYYAVNVPL 226
>UniRef50_Q5U8M9 Cluster: Histone deacetylase 1; n=2; Entamoeba
histolytica|Rep: Histone deacetylase 1 - Entamoeba
histolytica
Length = 448
Score = 169 bits (411), Expect = 8e-41
Identities = 76/200 (38%), Positives = 121/200 (60%), Gaps = 3/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITD---IDDDYISNA 462
R +LVH+LI YG+ +L + + A+ E + +FHS Y++ L+++T + + +
Sbjct: 27 RNKLVHHLIMEYGIYKRLNIYKPWRATNEQMEMFHSKEYIDFLQRVTPEMALQPHFKKSL 86
Query: 463 QDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
++ NF DCP ++ V T+ G S+ A + ADI +NW GG HHA ++A G
Sbjct: 87 EEFNFTD--DCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASG 144
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
FCY+NDIV AI +L +LY+D+D HHG+GV++A+ T V T S HK+ ++PGT
Sbjct: 145 FCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGT 204
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G ++++G +G+ YS N PL
Sbjct: 205 GDVDEVGIDEGKNYSINVPL 224
>UniRef50_Q94D35 Cluster: Histone deacetylase-like; n=9; Oryza
sativa|Rep: Histone deacetylase-like - Oryza sativa
subsp. japonica (Rice)
Length = 481
Score = 167 bits (406), Expect = 3e-40
Identities = 85/211 (40%), Positives = 127/211 (60%), Gaps = 13/211 (6%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDID---DDYISN- 459
R + HNL+ AYG++ ++ +R++PA+ +L FH + YL L+ +T DD + +
Sbjct: 45 RVTMAHNLVAAYGMLGDMRRLRTAPATAAELADFHDEGYLALLQDLTPDGCGGDDGVGDM 104
Query: 460 --------AQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWH 615
+ + G G D P +++ +GGS+ AA+ L G ADIAINW GG H
Sbjct: 105 ARARGIYAVEGKGGGRGVDNPVFDRLWDYCLRYSGGSLAAARTLGSGTADIAINWSGGMH 164
Query: 616 HAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHK 795
HA A GFCYVNDIV+AI +L F+ +LYVD+DVHHG+GVQ A+ + V T+SFH+
Sbjct: 165 HACRGGARGFCYVNDIVLAIRELLAHFRRVLYVDIDVHHGDGVQAAFEASNRVMTVSFHQ 224
Query: 796 FEPGFYPGTGSIEDIG-CGDGEGYSCNFPLN 885
GF+PG+G++ D+G G G + N P++
Sbjct: 225 HGGGFFPGSGAVADVGKKGPGRYCALNVPVS 255
>UniRef50_Q4WHY0 Cluster: Histone deacetylase HosA; n=15;
Fungi/Metazoa group|Rep: Histone deacetylase HosA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 487
Score = 163 bits (396), Expect = 5e-39
Identities = 82/206 (39%), Positives = 120/206 (58%), Gaps = 8/206 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L L+ AYG+ + + + A+YE++ FH YL+ L+Q+ + D + Q E
Sbjct: 66 RLTLTKQLVMAYGMHHAMDLYLARAATYEEMAEFHQTDYLDFLRQV--MPGDMENPEQSE 123
Query: 472 N---FGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
N F G DCP ++ S AGGS+ AA+ L ++IA+NW GG HHA A G
Sbjct: 124 NIARFNFGDDCPIFNGLYNYCSLYAGGSIDAARKLCNNQSEIAVNWSGGLHHAKKAEASG 183
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE-PGFYPG 819
FCYVNDIV+ I +L ++Y+D+DVHHG+GV+ A+W+T V T+SFHK++ F+PG
Sbjct: 184 FCYVNDIVLGILQLLRHHPRVMYIDIDVHHGDGVEQAFWSTDRVLTVSFHKYDKDNFFPG 243
Query: 820 TGSIEDIG----CGDGEGYSCNFPLN 885
TG ++ G G ++ N PLN
Sbjct: 244 TGPLDSTGPTHPLNPGAHHAVNVPLN 269
>UniRef50_Q0V6A5 Cluster: Putative uncharacterized protein; n=2;
Pleosporales|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 507
Score = 162 bits (393), Expect = 1e-38
Identities = 89/210 (42%), Positives = 128/210 (60%), Gaps = 12/210 (5%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L L+ AYGL + + PA++ +L +FH YLE+L +IT + + Q
Sbjct: 86 RLTLTKQLVVAYGLEYTMDLYTPRPANFGELALFHDREYLEYLSKITP-QNAQPEDPQYI 144
Query: 472 NFGIG---YDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
++G G DCP ++ VS +G S++AA L +DIAINW GG HHA N A G
Sbjct: 145 SYGFGGDSNDCPVFDGLWNYVSLYSGASMSAAWNLLNKQSDIAINWSGGLHHAKKNLASG 204
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKF---EPG-- 807
FCYVNDIVIAI+ L + + +LY+D+DVHHG+GV+ A+ +T V+TLS+HK+ G
Sbjct: 205 FCYVNDIVIAIQLLLTQHQRVLYIDIDVHHGDGVEQAFESTDRVFTLSYHKYGIDRHGYP 264
Query: 808 FYPGTGSIEDIGCGD----GEGYSCNFPLN 885
F+PGTG+I + G D G+G+S N P++
Sbjct: 265 FFPGTGNINETGPHDPINRGKGHSLNIPID 294
>UniRef50_Q09440 Cluster: Putative histone deacetylase 2; n=2;
Caenorhabditis|Rep: Putative histone deacetylase 2 -
Caenorhabditis elegans
Length = 507
Score = 157 bits (382), Expect = 3e-37
Identities = 77/197 (39%), Positives = 119/197 (60%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + ++L+ +Y + + V+ S D++VFH++ Y+ L+ +T + +
Sbjct: 54 RLVVCNDLVVSYEMPKYMTVVESPKLDAADISVFHTEDYVNFLQTVTPKLGLTMPDDVLR 113
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F IG DCP +++ + AGGSV A+ L + DI INW GG HHA + A GFCY
Sbjct: 114 QFNIGEDCPIFAGLWDYCTLYAGGSVEGARRLNHKMNDIVINWPGGLHHAKKSEASGFCY 173
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+ I +L K +LY+D+D+HHG+GVQ+A+ + V T+SFH+F ++PG+GSI
Sbjct: 174 VNDIVLGILELLKYHKRVLYIDIDIHHGDGVQEAFNNSDRVMTVSFHRFGQ-YFPGSGSI 232
Query: 832 EDIGCGDGEGYSCNFPL 882
D G G G+ ++ N PL
Sbjct: 233 MDKGVGPGKYFAINVPL 249
>UniRef50_A4VDD9 Cluster: Histone deacetylase 1, 2 ,3; n=4;
Oligohymenophorea|Rep: Histone deacetylase 1, 2 ,3 -
Tetrahymena thermophila SB210
Length = 473
Score = 157 bits (381), Expect = 4e-37
Identities = 88/218 (40%), Positives = 123/218 (56%), Gaps = 21/218 (9%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITD------------ 435
R + H+LI YG+ L V + A+ E++ FH Y+E+L
Sbjct: 30 RISMTHSLIVGYGVYKDLDVYTTREATKEEIMQFHDQDYVEYLSNYVSSSKIDFLKKNGC 89
Query: 436 ----IDDDYISNA-QDENFGIGY--DCPPVPNM--FELVSTIAGGSVTAAKCLTMGIADI 588
ID+D +++ + + +GI DCP + F +ST GGS+ AA + ADI
Sbjct: 90 SIPLIDEDAKNDSDKKKQYGIDVQADCPGFDGLYTFSQLST-GGGSIDAAHLIINNAADI 148
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTR 768
AINW GG HHA A GFCYVNDIVI I +L F +LY+D+DVHHG+GV++A++TT
Sbjct: 149 AINWGGGLHHAKKGEAYGFCYVNDIVICILELLKVFPRVLYIDIDVHHGDGVEEAFYTTN 208
Query: 769 SVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
V T+SFH+F F+PGTG + G G G+ Y+ N PL
Sbjct: 209 RVMTVSFHEFGEDFFPGTGGLNSNGEGLGKNYAVNVPL 246
>UniRef50_Q6C3Y5 Cluster: Similar to CA1453|CaHOS1 Candida albicans
CaHOS1 Putative histone deacetylase; n=1; Yarrowia
lipolytica|Rep: Similar to CA1453|CaHOS1 Candida
albicans CaHOS1 Putative histone deacetylase - Yarrowia
lipolytica (Candida lipolytica)
Length = 424
Score = 157 bits (380), Expect = 5e-37
Identities = 75/208 (36%), Positives = 123/208 (59%)
Frame = +1
Query: 259 KECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDI 438
K C P+ GRA LV +L+ A L K+I +PA+ +L +HS LE++ +
Sbjct: 59 KVCSGRPSNEGRAALVDSLLVALQLHKSYKLIPITPATAAELQRYHS---LEYVSAVLKK 115
Query: 439 DDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHH 618
S + G+ +DCP P + V +AG +++ A+ L G + INW GG HH
Sbjct: 116 GQ---SEKTLDKMGLIHDCPIFPGLDAYVKLVAGSTLSCARQLMSGQHQLCINWYGGRHH 172
Query: 619 AHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKF 798
+ A GFCYVND+V+ I++++ +++ I+Y+D+D+HHG+ V A+ +++V +S H +
Sbjct: 173 GKRSAASGFCYVNDVVLGIQEMRKQYQKIMYIDVDLHHGDAVSAAFLHSKNVLCVSLHHY 232
Query: 799 EPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+ GF+PGTG++ D G G GE ++ N PL
Sbjct: 233 DTGFFPGTGALSDCGSGPGEYHTANVPL 260
>UniRef50_Q4QAJ4 Cluster: Histone deacetylase, putative; n=3;
Leishmania|Rep: Histone deacetylase, putative -
Leishmania major
Length = 536
Score = 156 bits (378), Expect = 8e-37
Identities = 84/207 (40%), Positives = 119/207 (57%), Gaps = 10/207 (4%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISK--LKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDD---DYIS 456
R R +H L+ + GL + + V + PA+ E++ FH YLE L+Q I D +S
Sbjct: 108 RVRALHALVHSLGLDNAECMTVCHARPATAEEMGAFHRSAYLECLRQAPVICGNPLDEMS 167
Query: 457 NAQDENFGIGY-----DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHA 621
A + F + + DCP P ++ LVS+ AG S+ A+ L G A +A+NW GG HHA
Sbjct: 168 LAFQKEFDVPFASQDSDCPLFPEVWALVSSQAGASLACAEALVRGDATVAMNWAGGMHHA 227
Query: 622 HNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE 801
A GFC+VNDIV+ I +L ++ +LYVDLDVHHG+GV+ A++ V TLS H+F
Sbjct: 228 AAAHASGFCFVNDIVLCIRRLLRYYQRVLYVDLDVHHGDGVEGAFYGNHRVMTLSLHQFG 287
Query: 802 PGFYPGTGSIEDIGCGDGEGYSCNFPL 882
GF+PGTG D ++ N PL
Sbjct: 288 NGFFPGTGDYPTRETAD--SFAINVPL 312
>UniRef50_A0PAD5 Cluster: Putative uncharacterized protein; n=2;
Ipomoea trifida|Rep: Putative uncharacterized protein -
Ipomoea trifida (Morning glory)
Length = 496
Score = 154 bits (374), Expect = 3e-36
Identities = 68/143 (47%), Positives = 95/143 (66%), Gaps = 1/143 (0%)
Frame = +1
Query: 454 SNAQDEN-FGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNN 630
S QD N + +G DCP N+FE AGG++ AA+ L + D+AINW GG HHA
Sbjct: 97 SPQQDGNLYNLGEDCPVFDNLFEFCQIYAGGTIDAARRLNNQLCDVAINWAGGLHHAKKC 156
Query: 631 RAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGF 810
A GFCY+ND+V+ I +L +LY+D+DVHHG+GV++A++ T V T+SFHK+ F
Sbjct: 157 EASGFCYINDLVLGILELLKYHPRVLYIDIDVHHGDGVEEAFYFTDRVMTVSFHKYGDKF 216
Query: 811 YPGTGSIEDIGCGDGEGYSCNFP 879
+PGTG ++DIG DG+ Y+ N P
Sbjct: 217 FPGTGDMKDIGERDGKFYAINVP 239
>UniRef50_A4RK28 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 466
Score = 153 bits (371), Expect = 6e-36
Identities = 81/206 (39%), Positives = 123/206 (59%), Gaps = 8/206 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITD--IDDDYISNAQ 465
R L LI +YG+ + S A+Y++L +FH+ Y++ L + I D +
Sbjct: 89 RLTLSKALISSYGMNFAMDNYVSRAATYDELTMFHASDYIQFLGTVLPEPIPRDVDNPYP 148
Query: 466 DENFGIG-YDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
D F +G DCP +++ S AGGS+ AA+ + +DIAI W GG HHA + A G
Sbjct: 149 DLKFNLGGSDCPLFEGLYDYCSMSAGGSLDAARKICNNQSDIAIAWGGGLHHAKRSEASG 208
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEP-GFYPG 819
FCY+NDIVIAI +L +LY+D+DVHHG+GV++A+++T V T+SFHK++P F+PG
Sbjct: 209 FCYINDIVIAILQLLRCHPRVLYIDIDVHHGDGVEEAFYSTDRVMTVSFHKYDPVNFFPG 268
Query: 820 TGSIEDIG----CGDGEGYSCNFPLN 885
TG +++ G G ++ N PL+
Sbjct: 269 TGPLDENGPKIELNRGAHHAINVPLS 294
>UniRef50_A5H660 Cluster: Histone deacetylase 8; n=3;
Schistosoma|Rep: Histone deacetylase 8 - Schistosoma
mansoni (Blood fluke)
Length = 440
Score = 151 bits (367), Expect = 2e-35
Identities = 83/219 (37%), Positives = 122/219 (55%), Gaps = 19/219 (8%)
Frame = +1
Query: 229 VAYLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIR----SSPAS-YEDLNVF 393
V ++ ++ + C P R LV +LI AY LI +L + SP+ YE + F
Sbjct: 3 VGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWDSPSRMYEAVTAF 62
Query: 394 HSDLYLEHLKQITDID-DDYISNAQDE----NFGIGYDCPPVPNMFELVSTIAGGSVTAA 558
HS Y++ LK++ + ++ A DE +F + YDCP P++F+ GS+ AA
Sbjct: 63 HSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYDCPGFPSVFDYSLAAVQGSLAAA 122
Query: 559 KCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL---------KGKFKNILY 711
L ++ INW GGWHHA + A GFCY+NDIV+AI +L + +LY
Sbjct: 123 SALICRHCEVVINWGGGWHHAKRSEASGFCYLNDIVLAIHRLVSSTPPETSPNRQTRVLY 182
Query: 712 VDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGS 828
VDLD+HHG+GV++A+W + V T S H PGF+PGTG+
Sbjct: 183 VDLDLHHGDGVEEAFWYSPRVVTFSVHHASPGFFPGTGT 221
>UniRef50_A0DPM0 Cluster: Chromosome undetermined scaffold_59, whole
genome shotgun sequence; n=7; Eukaryota|Rep: Chromosome
undetermined scaffold_59, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 443
Score = 150 bits (363), Expect = 5e-35
Identities = 83/205 (40%), Positives = 120/205 (58%), Gaps = 7/205 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVI-RSSPASY-----ED-LNVFHSDLYLEHLKQITDIDDDY 450
R + +L+ YGL + I +S +Y ED L FHS Y++ +K IT +
Sbjct: 50 RVAITDDLVGHYGLKQYMNCIDQSFVQTYIKRVDEDVLTQFHSYEYIDLIKIITPENKCQ 109
Query: 451 ISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNN 630
+ Q F DCP + +F+ GSV AA + ++IAINW GG HHA +
Sbjct: 110 YED-QLYRFNFMEDCPVLDRLFDFCLCQTSGSVGAACVIADQKSNIAINWSGGLHHAKQS 168
Query: 631 RAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGF 810
A GFCYVND V+ I +L ++ +LYVD+D+HHG+GV++A++ T V T SFHKF+ +
Sbjct: 169 EASGFCYVNDCVLGILELLKTYQRVLYVDIDIHHGDGVEEAFYLTDRVMTCSFHKFKE-Y 227
Query: 811 YPGTGSIEDIGCGDGEGYSCNFPLN 885
+PGTG I+D+G G+ Y+ NFPLN
Sbjct: 228 FPGTGHIDDVGHDKGKYYAVNFPLN 252
>UniRef50_Q74DU3 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=7; Desulfuromonadales|Rep: Histone
deacetylase/AcuC/AphA family protein - Geobacter
sulfurreducens
Length = 385
Score = 149 bits (362), Expect = 7e-35
Identities = 80/205 (39%), Positives = 115/205 (56%), Gaps = 3/205 (1%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLIS--KLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDY 450
P R L L+ AYGL+ +K++ A+ E L FH+ YL+ L++ ++ DD
Sbjct: 23 PFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEALLTFHAPDYLDRLREFSESDDA- 81
Query: 451 ISNAQDENFGIG-YDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHN 627
D +G+G D P +++ AGG++ AA+ + DIA N GGWHHAH
Sbjct: 82 ---RADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAEEGYDIAFNLAGGWHHAHR 138
Query: 628 NRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG 807
+A GF Y+ND V+AI L K + Y+D+D HHG+GVQ+A++ T V T+S H+
Sbjct: 139 AKASGFSYLNDAVVAINLLLEKGLRVAYLDIDAHHGDGVQEAFYDTDRVLTISIHESGMY 198
Query: 808 FYPGTGSIEDIGCGDGEGYSCNFPL 882
F+PGTG + G G G GYS N PL
Sbjct: 199 FFPGTGFEGETGTGAGTGYSVNIPL 223
>UniRef50_Q59Q78 Cluster: Likely histone deacetylase Hos1p; n=2;
Saccharomycetales|Rep: Likely histone deacetylase Hos1p
- Candida albicans (Yeast)
Length = 436
Score = 149 bits (361), Expect = 9e-35
Identities = 81/209 (38%), Positives = 120/209 (57%), Gaps = 22/209 (10%)
Frame = +1
Query: 274 LPAVFGRARLVHNLIEAYGLISKLK-VIRSSPASYEDLNVFHSDLYLEHL---------- 420
LP+ GR LV LIEAY LI I PA +DL +H D +++HL
Sbjct: 66 LPSNKGRQSLVLGLIEAYKLIDLCDGTIDIYPAQTKDLTTYHDDEFVKHLMGPRTFLDKN 125
Query: 421 -----KQITDIDDDYI-SNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA 582
K TD+ + I N DE +G+ +DC P P++ V A S+ AA+ + +
Sbjct: 126 FNKIDKAETDLTNIVIEENDLDEKYGLTFDCYPFPSLDLYVQLTAASSINAARKIVQQVK 185
Query: 583 D-----IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQ 747
+ IA+NW GG HH H + A GFCYVND+V++I L+ ++ Y+DLD+HHG+GV+
Sbjct: 186 ETKDQIIAVNWYGGRHHCHKSHAAGFCYVNDVVLSINILRKNLGSVFYLDLDLHHGDGVE 245
Query: 748 DAYWTTRSVYTLSFHKFEPGFYPGTGSIE 834
+A+ ++ V T S H+++ GFYPGTGS++
Sbjct: 246 NAFKFSKKVATCSIHRYDIGFYPGTGSLK 274
>UniRef50_A5DN16 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 385
Score = 148 bits (358), Expect = 2e-34
Identities = 77/198 (38%), Positives = 118/198 (59%), Gaps = 11/198 (5%)
Frame = +1
Query: 274 LPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYL-EHLKQ----ITDI 438
LP+ GR L +L A + V+ + A+ ++L FH ++ E L+Q + +I
Sbjct: 24 LPSNTGRMSLTTSLTRALKVDLGCDVVEAKDATDKELTSFHGKEFVTELLRQRGSNVEEI 83
Query: 439 DDD----YISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD--IAINW 600
DD+ + + E FG+ YDCP + V +AG S+ +A+ L D +AINW
Sbjct: 84 DDEKEAHFNKTSHLEKFGLVYDCPLFCGLDRYVRAVAGSSINSARKLLSDTKDHLLAINW 143
Query: 601 CGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYT 780
GG HH NRA GFCYVNDIV+AI L+ +++ + Y+DLD+HHG+GV+ A+ + SV T
Sbjct: 144 YGGRHHCQKNRAAGFCYVNDIVMAINVLRRRYRKVFYLDLDLHHGDGVESAFEHSSSVLT 203
Query: 781 LSFHKFEPGFYPGTGSIE 834
S H+++ GF+PGTGS++
Sbjct: 204 CSIHRYDVGFFPGTGSLK 221
>UniRef50_Q4QCE7 Cluster: Histone deacetylase, putative; n=7;
Trypanosomatidae|Rep: Histone deacetylase, putative -
Leishmania major
Length = 428
Score = 144 bits (348), Expect = 4e-33
Identities = 69/166 (41%), Positives = 96/166 (57%)
Frame = +1
Query: 376 EDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTA 555
E+L +H+D YL +L + ++ NA+ DCPPV + E A G++
Sbjct: 77 EELMAYHTDTYLANLGLHSC--RSWLWNAETSKVFFSGDCPPVEGLMEHSIATASGTLMG 134
Query: 556 AKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHG 735
A L G D+A++W GG HH+ GFCYVNDIV+ I +L +LYVD+D+HHG
Sbjct: 135 AVLLNSGQVDVAVHWGGGMHHSKCGECSGFCYVNDIVLGILELLKCHDRVLYVDIDMHHG 194
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCN 873
+GV +A+ T+ V+TLS HKF F+PGTG D+G G G YS N
Sbjct: 195 DGVDEAFCTSDRVFTLSLHKFGESFFPGTGHPRDVGYGRGRYYSMN 240
>UniRef50_Q3A415 Cluster: Deacetylase; n=1; Pelobacter carbinolicus
DSM 2380|Rep: Deacetylase - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 381
Score = 142 bits (345), Expect = 8e-33
Identities = 74/200 (37%), Positives = 117/200 (58%), Gaps = 3/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISK--LKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQ 465
R L + L++A L+S+ +++I + A+Y +L FH YL L++ + D +
Sbjct: 28 RFALTYALLDALHLLSRPGIRLIEAPRATYAELLSFHHPDYLRTLQEFS-CDS---TRRA 83
Query: 466 DENFGIG-YDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
D FG+G + P ++F+ VS GG++ AA+ + A N GGWHHAH RA G
Sbjct: 84 DFRFGLGDMENPVFEDLFDWVSLCCGGTMEAARQVLDKNCRCAFNMAGGWHHAHAARASG 143
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
F Y+ND V+AI + + + YVDLD HHG+GVQ+A++ T V T+S H+ F+P T
Sbjct: 144 FSYLNDAVVAINSMVARGFKVAYVDLDAHHGDGVQEAFYATDRVLTISLHEIGKDFFPYT 203
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G ++++G +G GY+ N P+
Sbjct: 204 GVVKELGTREGYGYAVNIPM 223
>UniRef50_A0CXG2 Cluster: Chromosome undetermined scaffold_30, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_30,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 482
Score = 139 bits (337), Expect = 8e-32
Identities = 66/160 (41%), Positives = 92/160 (57%), Gaps = 2/160 (1%)
Frame = +1
Query: 409 LEHLKQITDIDDDYISNAQDENFGIG--YDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA 582
LE + IT + + + + +G D P +F AG S+ A + G A
Sbjct: 107 LEEYRLITKWSQNKNTKNLNSEYKVGDSADNPTFSGLFSYCQFSAGASIDCAHTILTGQA 166
Query: 583 DIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWT 762
DIAINW GG HHA A GFCY+NDIV+ I +L + +LYVD+D HHG+GV++A++
Sbjct: 167 DIAINWSGGLHHAKKKEAAGFCYINDIVLCILELLRIYVRVLYVDIDCHHGDGVEEAFYL 226
Query: 763 TRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T V TLSFH++ F+PGTG + +G G G Y+ N PL
Sbjct: 227 TNRVMTLSFHQYGDDFFPGTGQLNSVGLGVGRYYAVNVPL 266
>UniRef50_O67135 Cluster: Acetoin utilization protein; n=2; Aquifex
aeolicus|Rep: Acetoin utilization protein - Aquifex
aeolicus
Length = 375
Score = 137 bits (331), Expect = 4e-31
Identities = 78/204 (38%), Positives = 114/204 (55%), Gaps = 2/204 (0%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYIS 456
P R L+ ++A LI + ++I+S PA+ E+L +FH++ Y+ L +
Sbjct: 22 PLKIPRVSLLLRFLDAMNLIDEKELIKSRPATKEELLLFHTEDYINTLMEAERCQCVPKG 81
Query: 457 NAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRA 636
+ N G GY+ P MF S G +V A + G ++A N GG HHA +RA
Sbjct: 82 AREKYNIG-GYENPVSYAMFTGSSLATGSTVQAIEEFLKG--NVAFNPAGGMHHAFKSRA 138
Query: 637 EGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFY 813
GFCY+ND + IE L+ K FK ILY+DLD HH +GVQ+A++ T V+ LS H+ +
Sbjct: 139 NGFCYINDPAVGIEYLRKKGFKRILYIDLDAHHCDGVQEAFYDTDQVFVLSLHQSPEYAF 198
Query: 814 P-GTGSIEDIGCGDGEGYSCNFPL 882
P G +E+IG G G+GY+ N PL
Sbjct: 199 PFEKGFLEEIGEGKGKGYNLNIPL 222
>UniRef50_Q6BS96 Cluster: Similar to CA1453|CaHOS1 Candida albicans
CaHOS1; n=1; Debaryomyces hansenii|Rep: Similar to
CA1453|CaHOS1 Candida albicans CaHOS1 - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 469
Score = 133 bits (321), Expect = 7e-30
Identities = 66/167 (39%), Positives = 98/167 (58%), Gaps = 5/167 (2%)
Frame = +1
Query: 346 KVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELV 525
K R + D + SD + + + D + NA+ E +G+ +DC P M E V
Sbjct: 138 KYNRKQESDSNDSGLELSDSF-DEITPFEDAETQEEDNAELETYGLLHDCYIFPFMSEYV 196
Query: 526 STIAGGSVTAAKCLTMGIAD-----IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKG 690
+ +A S+ AA LT D I INW GG HH N+A GFCY+NDIV++I L+
Sbjct: 197 NLVAASSIQAATRLTKERKDNRAQNIVINWYGGRHHCKKNKAAGFCYINDIVLSINVLRR 256
Query: 691 KFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
++ I Y+DLD+HHG+GV+ A+ +++V T S H+++ GFYPGTGS+
Sbjct: 257 NYRRIFYLDLDLHHGDGVESAFEFSKNVMTCSIHRYDIGFYPGTGSL 303
>UniRef50_P39067 Cluster: Acetoin utilization protein acuC; n=25;
Bacillaceae|Rep: Acetoin utilization protein acuC -
Bacillus subtilis
Length = 387
Score = 131 bits (317), Expect = 2e-29
Identities = 71/200 (35%), Positives = 109/200 (54%), Gaps = 2/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L ++L++ ++ AS E+L++ H+D Y++ +K + + E
Sbjct: 27 RVLLTYDLLKTINAFDDGDIVTPRLASEEELSLVHTDDYIQAVKLA---GAGKLPAEEGE 83
Query: 472 NFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
++G+G + PV M E S + GG++TAA + G A A N GG HH RA GFC
Sbjct: 84 SYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQALHAANLGGGLHHGFRGRASGFC 143
Query: 649 YVNDIVIAIEKLKGKFK-NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTG 825
ND +AI+ ++ K+ +LY+D D HHG+GVQ ++ V TLS H+ +PGTG
Sbjct: 144 IYNDSAVAIQYIQKKYSARVLYIDTDAHHGDGVQFTFYDNPDVCTLSIHETGRYLFPGTG 203
Query: 826 SIEDIGCGDGEGYSCNFPLN 885
I++ G G G GYS N PL+
Sbjct: 204 QIQEKGSGKGYGYSFNIPLD 223
>UniRef50_A0B926 Cluster: Histone deacetylase superfamily; n=1;
Methanosaeta thermophila PT|Rep: Histone deacetylase
superfamily - Methanosaeta thermophila (strain DSM 6194
/ PT) (Methanothrixthermophila (strain DSM 6194 / PT))
Length = 370
Score = 129 bits (311), Expect = 1e-28
Identities = 72/200 (36%), Positives = 104/200 (52%), Gaps = 3/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSP--ASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQ 465
R L + +IE YG P AS +DL + H Y++ +K+
Sbjct: 25 RIMLTYRMIEEYGFFLGYDTEVQMPYYASEDDLLMVHDPGYIQAVKE----------ERP 74
Query: 466 DENFGIGY-DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
D G+ D P P +++ + IAG S+ AAK + +A N GG HHA RA G
Sbjct: 75 DPALGLDEPDTPVFPGIYDASALIAGASIEAAKRVASEPC-VAFNLAGGLHHAFPARAAG 133
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
FC ND + I L+ +F +LY+D+D HHG+GVQ ++ SV T+S H+ +PGT
Sbjct: 134 FCVFNDCALGIRTLRKRFDRVLYIDIDAHHGDGVQYIFYEDPSVLTISIHESGKYLFPGT 193
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G +++IG GDG GYS N P+
Sbjct: 194 GFVDEIGSGDGYGYSANIPM 213
>UniRef50_Q6CVU3 Cluster: Similar to sp|Q12214 Saccharomyces
cerevisiae YPR068c HOS1; n=1; Kluyveromyces lactis|Rep:
Similar to sp|Q12214 Saccharomyces cerevisiae YPR068c
HOS1 - Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 441
Score = 128 bits (309), Expect = 2e-28
Identities = 60/140 (42%), Positives = 92/140 (65%), Gaps = 4/140 (2%)
Frame = +1
Query: 430 TDIDDDYISNAQDENF---GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINW 600
++IDD +S D++F G+ +DCP P + + I GG+++ + + IAINW
Sbjct: 131 SEIDD--VSKLDDKDFTKYGLQHDCPKFPFLSMYLQVIVGGTLSLLQHIDHQTPSIAINW 188
Query: 601 CGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVY 777
GG HHA + A GFCYVNDIV+ I+ L+ K +K + Y+D D+H+G+GV A+ + +V
Sbjct: 189 DGGRHHALKHYASGFCYVNDIVLLIQSLRRKGWKRVTYIDFDLHYGDGVAKAFRFSENVQ 248
Query: 778 TLSFHKFEPGFYPGTGSIED 837
T+S H +EPGF+PGTGS+E+
Sbjct: 249 TISVHLYEPGFFPGTGSLEE 268
>UniRef50_Q98RL4 Cluster: Histone deacetylase; n=1; Guillardia
theta|Rep: Histone deacetylase - Guillardia theta
(Cryptomonas phi)
Length = 374
Score = 126 bits (305), Expect = 6e-28
Identities = 66/197 (33%), Positives = 105/197 (53%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + LI +YG+ L++IR+ + ++ HS ++ I + + I+ +
Sbjct: 29 RLSMTSELIYSYGMEKFLRIIRTEKKTNSEMFNIHSSIF--EFNVIKKKNFESINYITID 86
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
+ DCP + E + + S+ + LT IAINW GG HH+ + GFCY
Sbjct: 87 KYDA--DCPIFKGLNEYLLLYSSASLLSLDELTNNNCQIAINWSGGLHHSKIDEKSGFCY 144
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
+NDI + I L F ILY+D+DVHHG+GV++ ++ T V+ LSFH + F+PG+GSI
Sbjct: 145 LNDINLCILNLLKHFNYILYIDIDVHHGDGVEEVFYATNRVFVLSFHFYNKNFFPGSGSI 204
Query: 832 EDIGCGDGEGYSCNFPL 882
+ G G+ S N P+
Sbjct: 205 TNKGISIGKYASYNVPI 221
>UniRef50_Q12214 Cluster: Histone deacetylase HOS1; n=2;
Saccharomyces cerevisiae|Rep: Histone deacetylase HOS1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 470
Score = 126 bits (303), Expect = 1e-27
Identities = 56/133 (42%), Positives = 81/133 (60%), Gaps = 1/133 (0%)
Frame = +1
Query: 442 DDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHA 621
D YI N++ + + + DCP + I G ++ L+ I INW GG HHA
Sbjct: 153 DTYILNSETKQYNLEGDCPIFSYLPMYCQVITGATLNLLDHLSPTERLIGINWDGGRHHA 212
Query: 622 HNNRAEGFCYVNDIVIAIEKL-KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKF 798
RA GFCY+ND+V+ I++L K K I YVD D+HHG+GV+ A+ ++ + T+S H +
Sbjct: 213 FKQRASGFCYINDVVLLIQRLRKAKLNKITYVDFDLHHGDGVEKAFQYSKQIQTISVHLY 272
Query: 799 EPGFYPGTGSIED 837
EPGF+PGTGS+ D
Sbjct: 273 EPGFFPGTGSLSD 285
>UniRef50_Q0S1K3 Cluster: Possible acetoin dehydrogenase; n=3;
Bacteria|Rep: Possible acetoin dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 423
Score = 125 bits (301), Expect = 2e-27
Identities = 72/199 (36%), Positives = 107/199 (53%), Gaps = 2/199 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L +L + G++ ++++R + AS DL H+ Y+E +KQ + A D
Sbjct: 41 RLELTMSLARSLGILEGVELLRPAAASDADLLRIHTPAYVEAVKQAGHSATSGVLGA-DA 99
Query: 472 NFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
G+G + PV P M E + +AGGS+ AA+ + G A++ GG HHA + A GFC
Sbjct: 100 PHGLGTEDNPVFPQMHEASAILAGGSLAAAQEIAAGRTRRAVSIGGGMHHAMPDWASGFC 159
Query: 649 YVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTG 825
ND+ IAI L F I Y+D+D HHG+GVQ A+ V T+S H+ +P TG
Sbjct: 160 VYNDVAIAISWLLDHGFDRIAYIDVDAHHGDGVQHAFAHDPRVLTISLHQHPATLWPNTG 219
Query: 826 SIEDIGCGDGEGYSCNFPL 882
++G G GEG + N P+
Sbjct: 220 WSSEVGEGSGEGTAVNLPV 238
>UniRef50_Q381M6 Cluster: Histone deacetylase 2; n=4;
Trypanosoma|Rep: Histone deacetylase 2 - Trypanosoma
brucei
Length = 566
Score = 116 bits (278), Expect(2) = 3e-26
Identities = 58/143 (40%), Positives = 81/143 (56%), Gaps = 4/143 (2%)
Frame = +1
Query: 466 DENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGF 645
D+ F + D P M+ + G++ A + L AI+W GG H+A A G
Sbjct: 140 DKRFNLVGDSAPFSGMWRFTQAVVSGTLAATRLLAQPSRFAAIHWMGGKHNAKRASAGGS 199
Query: 646 CYVNDIVIAI---EKLKGKFKNI-LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFY 813
C VND+V+A+ KL +N+ L VDLD HHG+G Q+A+ + V TLS H + G +
Sbjct: 200 CLVNDVVLAVLELRKLLPANRNVVLAVDLDAHHGDGAQEAFLSDPRVVTLSLHAYGIGIF 259
Query: 814 PGTGSIEDIGCGDGEGYSCNFPL 882
PGTGS+E+IG G G GY+ N PL
Sbjct: 260 PGTGSLEEIGSGLGRGYTMNIPL 282
Score = 26.2 bits (55), Expect(2) = 3e-26
Identities = 12/38 (31%), Positives = 24/38 (63%), Gaps = 3/38 (7%)
Frame = +1
Query: 349 VIRSSPA-SYEDLNVFHSDLYLEH--LKQITDIDDDYI 453
V R+ P+ ED+ VFH + Y+ + L+++ DD+++
Sbjct: 66 VDRNLPSVDVEDMTVFHDESYVRYLSLREVASGDDEHV 103
>UniRef50_Q1AX98 Cluster: Histone deacetylase superfamily; n=2;
Bacteria|Rep: Histone deacetylase superfamily -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 387
Score = 120 bits (290), Expect = 4e-26
Identities = 72/200 (36%), Positives = 104/200 (52%), Gaps = 3/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R RL L +A GL+ + P S E+L H+ Y+ ++Q + D +
Sbjct: 28 RIRLTLELCDALGLLDGYDFLAPEPVSEEELTSVHTLTYVRMVQQASRGAGD---PERLL 84
Query: 472 NFGIGY-DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
++G+G D P M E S + GG+V A + + G A+ A+ GG HHA ++A GFC
Sbjct: 85 DYGLGTPDNPLFAGMHEACSRVVGGTVLACRLVAAGEAEHAMCISGGLHHALRSKASGFC 144
Query: 649 YVNDIVIAIEKLKGKFKNI--LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
ND +AI LK + I YVD D HHG+GVQ ++ V T+S H+ +PGT
Sbjct: 145 IYNDAAVAIALLKRERPGIRVAYVDTDAHHGDGVQWMFYEDPEVLTVSMHESGRYLFPGT 204
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G +++ G G G GYS N PL
Sbjct: 205 GGVDEKGRGAGAGYSVNVPL 224
>UniRef50_Q2S035 Cluster: Acetoin utilization protein acuC; n=4;
Bacteria|Rep: Acetoin utilization protein acuC -
Salinibacter ruber (strain DSM 13855)
Length = 378
Score = 120 bits (289), Expect = 5e-26
Identities = 67/197 (34%), Positives = 104/197 (52%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + +L+ A G + L + S A+ E++ H + ++E ++ +D + A
Sbjct: 25 RQEMTMDLLAALG--APLNPVAPSVATREEVRRVHGEQFVEKVEAASDGTPPPEARAFGL 82
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
+ G D P NM + GG++ A+ + G A + + GG HHAH RA GFC
Sbjct: 83 DTG---DVPVFENMDAAARGLVGGTLHGARLIGDGDATRVLQFGGGLHHAHRARASGFCV 139
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
ND+ +AI L+ + + YVD+DVHHG+GVQ + V T+S H+ +PGTG +
Sbjct: 140 YNDLSVAIHALREQGLRVAYVDVDVHHGDGVQHLHDDDPGVLTVSLHETGRALFPGTGHV 199
Query: 832 EDIGCGDGEGYSCNFPL 882
E+IG G G G+S N PL
Sbjct: 200 EEIGKGAGRGFSLNVPL 216
>UniRef50_Q981B8 Cluster: Acetylpolyamine aminohydrolase; n=4;
Sulfolobaceae|Rep: Acetylpolyamine aminohydrolase -
Sulfolobus solfataricus
Length = 351
Score = 120 bits (289), Expect = 5e-26
Identities = 63/197 (31%), Positives = 94/197 (47%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + L+E G + ++ E L + HS Y+E +K + Y+ +
Sbjct: 27 RESMTKRLLEERGAFHFITLVEPKSIPEEALQLVHSKEYIEFVKYKSKEGQGYLDDG--- 83
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
D P ++E GSV A + + G + IN GG+HHA NRA GFC
Sbjct: 84 ------DTPAFKGIYEAALIRVSGSVKALELIKSGEFNHTINIGGGFHHAKRNRAAGFCV 137
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
ND+ + + + F I VD+D HH +G Q+ ++ +S H F P F+PGTG +
Sbjct: 138 FNDVALISKLGESFFSRIAIVDIDGHHADGTQELLIDDNNILKISLHMFHPNFFPGTGDV 197
Query: 832 EDIGCGDGEGYSCNFPL 882
+IG G GEGY+ N PL
Sbjct: 198 NEIGLGKGEGYTINIPL 214
>UniRef50_Q8SQN9 Cluster: HISTONE DEACETYLASE; n=1; Encephalitozoon
cuniculi|Rep: HISTONE DEACETYLASE - Encephalitozoon
cuniculi
Length = 344
Score = 120 bits (288), Expect = 7e-26
Identities = 70/207 (33%), Positives = 112/207 (54%), Gaps = 2/207 (0%)
Frame = +1
Query: 229 VAYLWDEK--LVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD 402
VAY++DE+ L R P R + H+L++++GL K+ +++ P + L+ +H++
Sbjct: 3 VAYMFDEEVGLFHYGPRHPMKPFRTVVTHSLVKSFGLDKKMTIVK--PEVFP-LSSYHTE 59
Query: 403 LYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA 582
YL +L ++E DCP + S+ +A L+ G
Sbjct: 60 EYLGNL-------------GKNET----PDCPNFIGLPRFCELYGSASINSAMILSEGAY 102
Query: 583 DIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWT 762
INW GG HHAH GFC+VNDIV+AI +L ++ ++Y+D+DVHHG+GV++A+
Sbjct: 103 STVINWSGGLHHAHKAIPSGFCHVNDIVLAILELLKTYRRVMYIDIDVHHGDGVEEAFLE 162
Query: 763 TRSVYTLSFHKFEPGFYPGTGSIEDIG 843
V TLS HK+ GF+P TG++ G
Sbjct: 163 CDRVLTLSLHKYGDGFFPETGTLITTG 189
>UniRef50_Q75BA6 Cluster: ADL339Wp; n=1; Eremothecium gossypii|Rep:
ADL339Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 437
Score = 118 bits (285), Expect = 2e-25
Identities = 55/131 (41%), Positives = 86/131 (65%), Gaps = 2/131 (1%)
Frame = +1
Query: 451 ISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD-IAINWCGGWHHAHN 627
+++A +G+ DCP + + + T+AG ++ AK L+ +A+NW GG HHA
Sbjct: 138 MASAALAKYGLHDDCPVMDYLPMYIHTVAGATLALAKELSRHRGSALAVNWDGGRHHALK 197
Query: 628 NRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEP 804
RA GFCYVNDI + I+ L+ + F + YVD D+HHG+GV++A+ +++V T S H FEP
Sbjct: 198 ARASGFCYVNDIALLIQTLRRQGFLRVSYVDFDLHHGDGVENAFRYSKNVQTCSLHLFEP 257
Query: 805 GFYPGTGSIED 837
GF+PGTG+ ++
Sbjct: 258 GFFPGTGACKN 268
Score = 34.3 bits (75), Expect = 4.3
Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKL-KVIRSSPASYEDLNVFHSDLYL 411
+++L+H ++ AYGL+ KVI + A+ LN FHS YL
Sbjct: 25 KSQLIHGMLGAYGLLQHFDKVITAPYATKHTLNKFHSMQYL 65
>UniRef50_A7TRW5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 518
Score = 116 bits (279), Expect = 8e-25
Identities = 54/126 (42%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
Frame = +1
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEG 642
+ F + DCP + I+G S+ + + + IAINW GG HHA N+A G
Sbjct: 173 KKFNLEGDCPLFSFLPLYCEVISGASLMLSDFIEKSSSQRTIAINWDGGRHHAIKNKASG 232
Query: 643 FCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
FCY+NDIVI I+KL+ K + Y+D D+HHG+GV+ A+ + ++ T+S H +EPGF+P
Sbjct: 233 FCYINDIVILIQKLRKKGISKVSYIDFDLHHGDGVEKAFRYSSNIQTISMHMYEPGFFPC 292
Query: 820 TGSIED 837
TGS+ED
Sbjct: 293 TGSLED 298
>UniRef50_A0K0A0 Cluster: Histone deacetylase superfamily; n=2;
Arthrobacter|Rep: Histone deacetylase superfamily -
Arthrobacter sp. (strain FB24)
Length = 407
Score = 114 bits (275), Expect = 2e-24
Identities = 68/201 (33%), Positives = 104/201 (51%), Gaps = 4/201 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSP--ASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQ 465
R L L + GL+ V ++P A ++L HS ++ +++++ D+
Sbjct: 37 RMELTARLARSLGLLDLGHVTVAAPEVAGDDELCTVHSAEFVAAVRRVSLNPDE-----P 91
Query: 466 DENFGIGY-DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
D G+G D P M E + +AGGS+ AA + G A A+N+ GG HHA RA G
Sbjct: 92 DLERGLGTEDDPAFAGMHEASARLAGGSLMAASAILDGSAVRAVNFGGGMHHAAKERASG 151
Query: 643 FCYVNDIVIAIEK-LKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
FC ND +AI+K L G + + Y+D+D HHG+G Q +W V T+S H+ +PG
Sbjct: 152 FCIYNDAALAIQKLLDGGLQRVAYIDVDAHHGDGTQSIFWDDPRVLTISLHETGLTLFPG 211
Query: 820 TGSIEDIGCGDGEGYSCNFPL 882
TG +IG + +G + N L
Sbjct: 212 TGFANEIGGPNAQGSAVNVAL 232
>UniRef50_Q4P6M9 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 568
Score = 82.2 bits (194), Expect(2) = 5e-24
Identities = 36/73 (49%), Positives = 49/73 (67%)
Frame = +1
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
+ FG+ DCP + + VS +AG ++TAA+ L G ADIAI W GG HHA + A GFC
Sbjct: 191 DQFGLQDDCPAFEGLQQHVSLVAGAAITAAELLATGQADIAIAWDGGRHHAKKSSASGFC 250
Query: 649 YVNDIVIAIEKLK 687
Y+ND+V+AI L+
Sbjct: 251 YINDVVLAILSLR 263
Score = 52.4 bits (120), Expect(2) = 5e-24
Identities = 19/38 (50%), Positives = 30/38 (78%)
Frame = +1
Query: 703 ILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
+LY+D D+H G+GV++A+ +T +V TLS H + PGF+P
Sbjct: 301 VLYLDFDLHWGDGVEEAFHSTSNVLTLSIHHYAPGFFP 338
>UniRef50_Q97Z24 Cluster: Acetoin utilization protein; n=3;
Sulfolobaceae|Rep: Acetoin utilization protein -
Sulfolobus solfataricus
Length = 348
Score = 110 bits (265), Expect = 4e-23
Identities = 73/217 (33%), Positives = 113/217 (52%), Gaps = 2/217 (0%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAV--FGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYL 411
+WD++ + P + +AR+ + A +S ++ IR A+ EDL V H+ Y+
Sbjct: 15 VWDQRFTEISFSHPMIRDISKARVRDFIKLAKEKVSFVE-IRPEYATKEDLMVVHTRDYI 73
Query: 412 EHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIA 591
L++ + I YI D+ + Y P MFE + + G S TA K D
Sbjct: 74 GLLEESSKIP--YIGFL-DQGDTVHY-----PGMFEDILLVLGSSFTAIKYSKF--LDYV 123
Query: 592 INWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRS 771
GG+HHA NRA GFC +ND+ I KL K + + VD+D HHGNG+Q + +
Sbjct: 124 YIPLGGFHHAMPNRAVGFCPINDVAITALKLLEKGERVAIVDVDAHHGNGLQFILY-DKP 182
Query: 772 VYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+ ++ + ++ F+PGTG I++IG G G GY+ N PL
Sbjct: 183 ILKINIYAYDGNFFPGTGKIDEIGEGKGRGYNINIPL 219
>UniRef50_A3JH86 Cluster: Deacetylase / probable acetylpolyamine
aminohydrolase; n=1; Marinobacter sp. ELB17|Rep:
Deacetylase / probable acetylpolyamine aminohydrolase -
Marinobacter sp. ELB17
Length = 376
Score = 109 bits (262), Expect = 9e-23
Identities = 70/200 (35%), Positives = 106/200 (53%), Gaps = 5/200 (2%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENF 477
R + NL+E GLI +L V++ PA+ EDL FH+ YL+ L++ D+ +
Sbjct: 52 RRLKNLLEVSGLIDELVVVKPPPATREDLEYFHTGRYLDELEK-GDL----------QGG 100
Query: 478 GIGYDCPP-VPNMFELVSTIAGGSVTAAKCLTMGIADIAINWC-GGWHHAHNNRAEGFCY 651
G G DC P AG ++ A + + +GI A C HHA ++R GFC
Sbjct: 101 GDGGDCAPYTAGSLAAAKQSAGLAIAAVEDVALGIRRRAYALCRPPGHHAESDRGRGFCL 160
Query: 652 VNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-GT 822
+ +I +AI++ + G+ + +D DVHHGNG Q A++ V+TLS H + G YP T
Sbjct: 161 LGNIPVAIKRARALGQIGRVAVLDWDVHHGNGTQSAFYDDPDVFTLSIH--QAGNYPLDT 218
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G+ E+ G G G G + N P+
Sbjct: 219 GAFEEQGEGAGLGCNLNAPM 238
>UniRef50_A5E4H2 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 410
Score = 109 bits (261), Expect = 1e-22
Identities = 53/141 (37%), Positives = 77/141 (54%), Gaps = 12/141 (8%)
Frame = +1
Query: 466 DENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT-----------MGIADIAINWCGGW 612
DEN+G+ +DC P M V+ A ++ A + + I I INW GG
Sbjct: 115 DENYGLTHDCYVFPFMRHYVALTAASTIELATHIARMVVNSRDSDDLHIRPIGINWYGGR 174
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKL-KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSF 789
HH H + GFCY+ND+V+ I L K + Y+DLD+HHG+G+ A+ ++ V T S
Sbjct: 175 HHCHRAKCSGFCYINDVVLGINALRKLTSATVFYLDLDLHHGDGISQAFQYSKKVTTCSI 234
Query: 790 HKFEPGFYPGTGSIEDIGCGD 852
H+F+ GF+PGTG + GD
Sbjct: 235 HRFDVGFFPGTGDVRASVNGD 255
>UniRef50_UPI00015BAE44 Cluster: histone deacetylase superfamily;
n=1; Ignicoccus hospitalis KIN4/I|Rep: histone
deacetylase superfamily - Ignicoccus hospitalis KIN4/I
Length = 326
Score = 107 bits (257), Expect = 4e-22
Identities = 45/93 (48%), Positives = 59/93 (63%)
Frame = +1
Query: 604 GGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTL 783
GG HHA RA GFC ND+ + E L K + Y+D DVHHG+G Q+ ++ V T+
Sbjct: 113 GGLHHAGKCRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHHGDGTQEIFYERSDVLTV 172
Query: 784 SFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
S H + PGFYPGTG ++G G+G+GYS N PL
Sbjct: 173 SVHMYYPGFYPGTGWYAELGAGEGKGYSLNVPL 205
>UniRef50_Q6FWB7 Cluster: Similar to sp|Q12214 Saccharomyces
cerevisiae YPR068c HOS1; n=1; Candida glabrata|Rep:
Similar to sp|Q12214 Saccharomyces cerevisiae YPR068c
HOS1 - Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 445
Score = 107 bits (257), Expect = 4e-22
Identities = 54/146 (36%), Positives = 84/146 (57%), Gaps = 4/146 (2%)
Frame = +1
Query: 424 QITDID--DDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA-DIAI 594
+++D++ D+ + F + DCP P + G +++ A+ + G IAI
Sbjct: 137 ELSDVESGDEVTRRSTLAKFNLLDDCPIFPYLPLYCYVSTGATLSLAQYILEGSERTIAI 196
Query: 595 NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK-GKFKNILYVDLDVHHGNGVQDAYWTTRS 771
NW GG HH+ +A GFCY+NDI + I L+ G I YVD D+HHG+GV+ A+ ++
Sbjct: 197 NWDGGRHHSMKTKASGFCYINDIALLIMTLRRGGVDRISYVDFDLHHGDGVEKAFKYSKQ 256
Query: 772 VYTLSFHKFEPGFYPGTGSIEDIGCG 849
V T+S H +E GF+P +GS+ED G
Sbjct: 257 VQTISLHMYETGFFPCSGSLEDNSSG 282
>UniRef50_UPI000050FC36 Cluster: COG0123: Deacetylases, including
yeast histone deacetylase and acetoin utilization
protein; n=1; Brevibacterium linens BL2|Rep: COG0123:
Deacetylases, including yeast histone deacetylase and
acetoin utilization protein - Brevibacterium linens BL2
Length = 401
Score = 103 bits (246), Expect = 8e-21
Identities = 58/163 (35%), Positives = 84/163 (51%), Gaps = 2/163 (1%)
Frame = +1
Query: 361 SPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGY-DCPPVPNMFELVSTIA 537
S + L H ++ +KQI D +S+ +GIG D P NM + +
Sbjct: 57 SDVEEDTLAKLHDADFIAAVKQIGD--GAVLSDEDARKYGIGTEDVPGFENMHAASAMLF 114
Query: 538 GGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYV 714
GSV +A+ + G A+N+ GG HHA + A GFC NDI AI + G ++ I Y+
Sbjct: 115 QGSVDSARAIISGDYSHAVNFTGGMHHAMPDHASGFCVYNDIAGAITEFLGAGYERIAYI 174
Query: 715 DLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIG 843
DLD HHG+GV+ +W V T+S H+ +PG+G DIG
Sbjct: 175 DLDAHHGDGVEKFFWDDPRVLTISMHESGKFLFPGSGFPADIG 217
>UniRef50_Q2J786 Cluster: Histone deacetylase superfamily; n=13;
Actinomycetales|Rep: Histone deacetylase superfamily -
Frankia sp. (strain CcI3)
Length = 426
Score = 103 bits (246), Expect = 8e-21
Identities = 65/201 (32%), Positives = 99/201 (49%), Gaps = 4/201 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISK--LKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQ 465
R L +L + G++ +++ R + AS + + + H +YL ++ D +
Sbjct: 47 RLELTMDLAMSLGVLDAPGIRISRPTLASDDLIGLIHDPVYLSAVRAAPDPAQARFAAL- 105
Query: 466 DENFGIGY-DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
FG+G D P M E + I GG++ AA+ + G A++ GG HHA A G
Sbjct: 106 ---FGLGTADNPIFERMHEAAALITGGTIEAARAVWSGPPRHAVSIAGGLHHAMPGMASG 162
Query: 643 FCYVNDIVIAIE-KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
FC ND IAI L + YVD+DVHHG+GVQ A++ V T+S H+ +PG
Sbjct: 163 FCIYNDPAIAIAWLLSAGAARVAYVDVDVHHGDGVQTAFYDDPRVLTISLHQTGSTLFPG 222
Query: 820 TGSIEDIGCGDGEGYSCNFPL 882
TG ++G EG + N L
Sbjct: 223 TGFPTEVGAPAAEGTAVNVAL 243
>UniRef50_A0IVC2 Cluster: Histone deacetylase superfamily; n=5;
Proteobacteria|Rep: Histone deacetylase superfamily -
Serratia proteamaculans 568
Length = 370
Score = 102 bits (245), Expect = 1e-20
Identities = 67/200 (33%), Positives = 102/200 (51%), Gaps = 5/200 (2%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENF 477
R + NL++ GL +L ++ + A+ EDL H YL+ KQ++D +
Sbjct: 47 RRMKNLMDVSGLSHQLSLLSAELATDEDLLRIHPANYLQRFKQLSDNGGGML-------- 98
Query: 478 GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCY 651
G + P P +E+ AG + A + + G + A++ G HH +++ GFC+
Sbjct: 99 --GEEAPLGPGSYEIAKLSAGLACAAVEAVLQGELENAYALSRPPG-HHCLPDQSMGFCF 155
Query: 652 VNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-GT 822
+ +I IAIE+ K K+ + +D DVHHGNG Q YW V TLS H + G +P G
Sbjct: 156 LANIPIAIERAKAKYGLGKVAVLDWDVHHGNGTQHIYWQRDDVLTLSLH--QDGCFPAGY 213
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
+D G G GEGY+ N PL
Sbjct: 214 SGEQDRGAGAGEGYNVNIPL 233
>UniRef50_A1RXP5 Cluster: Histone deacetylase superfamily; n=1;
Thermofilum pendens Hrk 5|Rep: Histone deacetylase
superfamily - Thermofilum pendens (strain Hrk 5)
Length = 360
Score = 98.7 bits (235), Expect = 2e-19
Identities = 50/149 (33%), Positives = 79/149 (53%), Gaps = 3/149 (2%)
Frame = +1
Query: 445 DYISNAQDENFGI-GY-DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHH 618
DY+ + G+ Y D P P +FE G++T A L +A N GG+HH
Sbjct: 75 DYVKRMSELGAGLLDYGDTPAYPGVFEKALLAVSGTLTLADILVKAGRGVAFNPQGGFHH 134
Query: 619 AHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHK 795
A A GFC ND+ +A ++ + ++ + +D+D HHG+G Q+ + + +S H
Sbjct: 135 ARRRSAGGFCVFNDVAVAARYVRERGYERVAIIDVDAHHGDGTQEILYRD-PLLKVSVHG 193
Query: 796 FEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+ GFYPGTG I+++G GDG + N P+
Sbjct: 194 YGYGFYPGTGWIDELGEGDGLCMNINVPI 222
>UniRef50_Q8WUI4 Cluster: Histone deacetylase 7a; n=41; Tetrapoda|Rep:
Histone deacetylase 7a - Homo sapiens (Human)
Length = 952
Score = 98.7 bits (235), Expect = 2e-19
Identities = 69/220 (31%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 540 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 599
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 600 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 659
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 660 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 718
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 719 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 758
>UniRef50_P64375 Cluster: Acetoin utilization protein acuC; n=15;
Staphylococcus|Rep: Acetoin utilization protein acuC -
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length = 389
Score = 98.7 bits (235), Expect = 2e-19
Identities = 62/226 (27%), Positives = 113/226 (50%), Gaps = 4/226 (1%)
Frame = +1
Query: 217 NNARVAYLWDEKLVKECIRLPAVFG--RARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
++++ AY++ +KL++ F R +L L+ L+S ++++ A+ ++L +
Sbjct: 4 HSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDELML 63
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIG-YDCPPVPNMFELVSTIAGGSVTAAKCL 567
H Y+E +K + IS + + +G+ + +M +TI GG++T A +
Sbjct: 64 IHKYDYVEAIKHASH---GIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLI 120
Query: 568 TMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF-KNILYVDLDVHHGNGV 744
G + GG HHA RA GFC NDI I + + ++ + +L +D D HHG+G
Sbjct: 121 MSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEYNQRVLIIDTDAHHGDGT 180
Query: 745 QDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
Q +++ V T S H+ +PG+G + G G G++ N PL
Sbjct: 181 QWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPL 226
>UniRef50_Q28M71 Cluster: Histone deacetylase superfamily; n=15;
Alphaproteobacteria|Rep: Histone deacetylase superfamily
- Jannaschia sp. (strain CCS1)
Length = 375
Score = 97.9 bits (233), Expect = 3e-19
Identities = 67/200 (33%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R V +L A G + + S A L+V+H+ Y+ L+Q D +++A +
Sbjct: 26 RVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWHTPAYIAALQQAEA--DQAVTDAVRD 83
Query: 472 NFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
G+G P+ P MF +T AG S+ A + L G + + GG HH +RA GFC
Sbjct: 84 RHGLGTVSNPIYPEMFRRPATAAGASLLAGELLKDG--GVIYHPGGGTHHGMRDRAGGFC 141
Query: 649 YVNDIVIAIEKL-KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTG 825
Y+ND V+A+ L + + I YVD+D HH +GV+DA+ +S H E +P TG
Sbjct: 142 YLNDPVLAMLSLRRNGARRIAYVDIDAHHCDGVEDAFAGDPDTLLISVH--EEKRWPFTG 199
Query: 826 SIEDIGCGDGEGYSC-NFPL 882
++ED G G +C N P+
Sbjct: 200 ALEDDGATPGGVANCLNLPV 219
>UniRef50_A0LGT0 Cluster: Histone deacetylase superfamily; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Histone
deacetylase superfamily - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 316
Score = 96.3 bits (229), Expect = 9e-19
Identities = 65/226 (28%), Positives = 106/226 (46%), Gaps = 7/226 (3%)
Frame = +1
Query: 226 RVAYLWDEKLVKECI--RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHS 399
+ +L+D++L+ C P R V+ +E GL +L +I++SPA + + HS
Sbjct: 3 KTGFLYDDRLLLHCTGSNHPESPERLEAVYRGVEEAGLFPRLTLIKASPAKLKWIEAVHS 62
Query: 400 DLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI 579
++ ++ ++ + ++ Y E GG + A + + GI
Sbjct: 63 PKHIMRFEEACLLEMGEFDHPDNQMCRESY---------ETALLAVGGLLEAVRMVMEGI 113
Query: 580 ADIAINWCG---GWHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGV 744
D A +C HHA NRA GFCY N++ IA L ++ + + VD+D HHGNG
Sbjct: 114 IDNA--FCAVRPPGHHAEMNRALGFCYFNNVAIAARYLLNEWGVERVGIVDIDAHHGNGT 171
Query: 745 QDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
Q + SV+ S H+ +PGTG + G G G G++ N PL
Sbjct: 172 QHIFEDDPSVFYYSAHEHPSFAFPGTGREFETGVGAGSGFTLNCPL 217
>UniRef50_O27262 Cluster: Uncharacterized protein MTH_1194; n=1;
Methanothermobacter thermautotrophicus str. Delta H|Rep:
Uncharacterized protein MTH_1194 - Methanobacterium
thermoautotrophicum
Length = 331
Score = 95.9 bits (228), Expect = 1e-18
Identities = 60/200 (30%), Positives = 95/200 (47%), Gaps = 2/200 (1%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
GR R + IE+ L + + A +D+ + HS ++E+L+ ++
Sbjct: 22 GRTRAILRAIESSDLSPRF--VEPGMAGIDDILMVHSSTHVEYLEVFAGRGGGWLD---- 75
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
YD P F + AGG++ AA+ ++ G HHA +R+ GFC
Sbjct: 76 ------YDTYMTPESFSVARLSAGGAMLAAEEALRDGWSYSLGRPPG-HHATYDRSMGFC 128
Query: 649 YVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
N+I IAIE + L +D DVHHGNG ++ R V +S H+ +PGT
Sbjct: 129 IFNNIAIAIEHARRNLGVSRPLVLDFDVHHGNGTSSIFYRDRDVMYISIHQDPRTLFPGT 188
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G I++ G G+GEG++ N P+
Sbjct: 189 GFIDETGSGEGEGFNLNIPM 208
>UniRef50_Q1PVG5 Cluster: Similar to histone deacetylase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
histone deacetylase - Candidatus Kuenenia
stuttgartiensis
Length = 313
Score = 95.1 bits (226), Expect = 2e-18
Identities = 61/203 (30%), Positives = 100/203 (49%), Gaps = 6/203 (2%)
Frame = +1
Query: 295 ARLVHNLI---EAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQ 465
AR + N I E+ ++ + + + A E++ H Y+ ++QI D ++
Sbjct: 23 ARRIENTIKYLESDNFLAHVTIEKPRAALPEEIGFIHPKTYISTIQQIADSGGGWLDG-- 80
Query: 466 DENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEG 642
D + + + AG ++TA + G A A HHA +R G
Sbjct: 81 --------DTAVSGHSYNVALYSAGAALTAIDLIMKGEAKNAFCLVRPPGHHATPDRGMG 132
Query: 643 FCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
FC N++ IA L+ + K IL +D DVHHGNG QDA++ +V S H++ FYP
Sbjct: 133 FCLFNNVAIAARYLQKNYQQKRILIIDWDVHHGNGTQDAFYVDPTVMYFSMHRYP--FYP 190
Query: 817 GTGSIEDIGCGDGEGYSCNFPLN 885
GTG+ ++ G G+G+G++ N PL+
Sbjct: 191 GTGAEDETGEGNGKGFNINIPLS 213
>UniRef50_A3J841 Cluster: Histone deacetylase family protein; n=2;
Gammaproteobacteria|Rep: Histone deacetylase family
protein - Marinobacter sp. ELB17
Length = 367
Score = 95.1 bits (226), Expect = 2e-18
Identities = 48/129 (37%), Positives = 68/129 (52%), Gaps = 3/129 (2%)
Frame = +1
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEK 681
P+ + + AG ++ A + + G A A HHA RA GFC +N++ +A
Sbjct: 115 PDSIKAATAAAGNAIAAVESVCKGEAQSAFALVRPPGHHAEPVRARGFCLLNNVAVAAAH 174
Query: 682 LKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDG 855
+ K + +L +D D HHGNG QD +W V H P FYPG+G IE++G G G
Sbjct: 175 AQAKLGCERVLIIDWDAHHGNGTQDIFWADPDVLFFDTHCAAP-FYPGSGLIEEVGVGLG 233
Query: 856 EGYSCNFPL 882
EGY+ N PL
Sbjct: 234 EGYTINVPL 242
>UniRef50_A5D0K9 Cluster: Deacetylases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Deacetylases - Pelotomaculum
thermopropionicum SI
Length = 355
Score = 94.7 bits (225), Expect = 3e-18
Identities = 57/200 (28%), Positives = 99/200 (49%), Gaps = 3/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + +++ G++ KL I+ PA+ E++++ H Y+E +K+ S
Sbjct: 33 RVKHTYEILKIAGMLEKLVTIKPRPATVEEVSLVHLPAYIERVKE--------FSKRGGG 84
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWC-GGWHHAHNNRAEGFC 648
+F G + P FE AGG+++A + + G + A HHA +A G+C
Sbjct: 85 SF--GNNTTGSPETFETALLAAGGTLSAVEAVLEGRVESAFALVRPPGHHARPGQAMGYC 142
Query: 649 YVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
+ N+ IA ++ +L +D D HHGNG ++ +++ SV S H+ YPGT
Sbjct: 143 FFNNAAIAARYAIKRYGLSRVLIIDWDEHHGNGTEEIFYSDPSVLYFSVHR--DWSYPGT 200
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G G G+G+G++ N PL
Sbjct: 201 GQAAKAGDGEGKGFNINVPL 220
>UniRef50_Q02CA3 Cluster: Histone deacetylase superfamily; n=1;
Solibacter usitatus Ellin6076|Rep: Histone deacetylase
superfamily - Solibacter usitatus (strain Ellin6076)
Length = 312
Score = 94.3 bits (224), Expect = 4e-18
Identities = 63/208 (30%), Positives = 101/208 (48%), Gaps = 5/208 (2%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDY 450
R P R V + ++ GL++K+ + + A+ E+L + H+ YL+ + Y
Sbjct: 19 RHPECPARFDAVLDGLDRAGLLAKMLRVEARDATQEELTLCHTPDYLKTARSDVASGRPY 78
Query: 451 ISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCG---GWHHA 621
+S D PN +++ +GG + A + G A A +C HHA
Sbjct: 79 LSTG---------DTDITPNSWDVAVRASGGVLNAVDAVLTGAARNA--FCAVRPPGHHA 127
Query: 622 HNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHK 795
+ R GFC +N++ IA + + + + VD DVHHGNG QD ++ SV+ S H+
Sbjct: 128 NAARGMGFCLLNNVAIAARYAQRRHGIERVAIVDWDVHHGNGTQDIFYREGSVFFFSTHQ 187
Query: 796 FEPGFYPGTGSIEDIGCGDGEGYSCNFP 879
+ YPGTG ++ G G GEG + NFP
Sbjct: 188 WP--LYPGTGRADETGEGPGEGTTMNFP 213
>UniRef50_Q64BV4 Cluster: Acetoin utilization protein; n=5;
Archaea|Rep: Acetoin utilization protein - uncultured
archaeon GZfos26F9
Length = 351
Score = 93.9 bits (223), Expect = 5e-18
Identities = 68/209 (32%), Positives = 102/209 (48%), Gaps = 7/209 (3%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYIS 456
P R R + +E G+ KL+ I + AS E L H+ Y+E ++ +
Sbjct: 24 PETAERLRAIIRKLEETGIAEKLRRIIPTKASKEQLRYVHAPEYIEEVEAM--------- 74
Query: 457 NAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD-----IAINWCGGWHHA 621
+ + D P +E ++ +A G VT A M ++ A+ G HHA
Sbjct: 75 -CRRGGGALDPDTPLCEATYE-IALLATGGVTKAGDEVMDESNSLKHVFALIRPPG-HHA 131
Query: 622 HNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHK 795
N+ GFC N+I IA E LK ++ +L D DVHHGNG Q ++ SV S H+
Sbjct: 132 TPNKGMGFCIFNNIAIATEHLKREYGINRVLIADWDVHHGNGTQRMFFDGASVLYFSTHQ 191
Query: 796 FEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+ YPGTG I+++G G+GEG++ N PL
Sbjct: 192 YP--HYPGTGWIDEVGKGEGEGFTVNVPL 218
>UniRef50_Q6KAT4 Cluster: MFLJ00062 protein; n=6; Eutheria|Rep:
MFLJ00062 protein - Mus musculus (Mouse)
Length = 852
Score = 93.1 bits (221), Expect = 9e-18
Identities = 40/90 (44%), Positives = 60/90 (66%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA ++ A GFC+ N + IA +L+ GK IL VD DVHHGNG Q ++ SV +S
Sbjct: 570 HHADHSTAMGFCFFNSVAIACRQLQQHGKASKILIVDWDVHHGNGTQQTFYQDPSVLYIS 629
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 630 LHRHDDGNFFPGSGAVDEVGTGSGEGFNVN 659
>UniRef50_A6EYD2 Cluster: Histone deacetylase superfamily protein;
n=1; Marinobacter algicola DG893|Rep: Histone
deacetylase superfamily protein - Marinobacter algicola
DG893
Length = 368
Score = 93.1 bits (221), Expect = 9e-18
Identities = 50/150 (33%), Positives = 74/150 (49%), Gaps = 4/150 (2%)
Frame = +1
Query: 445 DYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHH 618
D I + +DE+ + D V P E AG ++ A + + G + A HH
Sbjct: 93 DDIFSLRDESAWLDVDTTAVSPGSVEAAEVAAGTAIAAVEAVVEGRTNSAFAMVRPPGHH 152
Query: 619 AHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
A RA GFC N++ +A + + + +L VD D HHGNG QD +W H
Sbjct: 153 AEPVRARGFCLFNNVAVAAAHAQAELGCERVLIVDWDAHHGNGTQDIFWADPDTMFFDIH 212
Query: 793 KFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+ P FYPG+G++ D+G G GEG + N P+
Sbjct: 213 RAAP-FYPGSGALTDVGAGLGEGTTINVPM 241
>UniRef50_Q1AYS6 Cluster: Histone deacetylase superfamily; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Histone
deacetylase superfamily - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 342
Score = 92.7 bits (220), Expect = 1e-17
Identities = 59/181 (32%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 343 LKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFEL 522
++V RS PA L H YL+ L++++ + D + +G P +E
Sbjct: 42 VEVRRSEPAPEAALLAVHERGYLKLLRELSSSGGGVL----DPDTALG------PGSWEA 91
Query: 523 VSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK-FK 699
AG + AA+ G A A+ G HHA RA GFC +N+ +A + +
Sbjct: 92 ALLAAGAAAGAAEAALSGAASFALVRPPG-HHAGRGRAMGFCLINNAAVAAAHARALGAR 150
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFP 879
+ +D DVHHGNG Q+ ++ V LS H+ FYPGTG E++G G G+G++ N P
Sbjct: 151 RVAVLDWDVHHGNGTQEIFYAAGDVLYLSVHRGGL-FYPGTGHPEEVGAGPGKGFTVNVP 209
Query: 880 L 882
L
Sbjct: 210 L 210
>UniRef50_Q4SMC8 Cluster: Chromosome 3 SCAF14553, whole genome shotgun
sequence; n=2; Tetraodontidae|Rep: Chromosome 3
SCAF14553, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1155
Score = 92.3 bits (219), Expect = 2e-17
Identities = 68/212 (32%), Positives = 107/212 (50%), Gaps = 13/212 (6%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYL-----EHLKQITDID 441
P GR + + + ++ GL ++ + IR A+ E+L HS+ ++ L+Q D
Sbjct: 727 PEHAGRIQSIWSRLQETGLRAQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDCS 786
Query: 442 DDYISNAQDENFGIGYDCPPVPNMFELVST--IAGGSVTAA--KCLTMGIAD-IAINWCG 606
+ + GIG D + N S +A GSV K T + + A+
Sbjct: 787 ITPMF-VRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVAELVFKVATRELKNGFAVVRPP 845
Query: 607 GWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYT 780
G HHA + GFCY N + IA + L+ + IL VD DVHHGNG Q A++ SV
Sbjct: 846 G-HHAEESTPMGFCYFNSVAIAAKLLQQRLNINKILIVDWDVHHGNGTQQAFYDDPSVLY 904
Query: 781 LSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
LS H+++ G F+PG+G+ +++G G G G++ N
Sbjct: 905 LSIHRYDDGNFFPGSGAPDEVGSGPGVGFNVN 936
>UniRef50_UPI0000E463DB Cluster: PREDICTED: similar to histone
deacetylase-4; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to histone deacetylase-4 -
Strongylocentrotus purpuratus
Length = 1012
Score = 91.5 bits (217), Expect = 3e-17
Identities = 70/213 (32%), Positives = 106/213 (49%), Gaps = 18/213 (8%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHL----KQITDIDDDYIS 456
GR + + + G++S+ + IR+ AS E+L HS+ Y +D ++
Sbjct: 650 GRLQSIWARLHERGIVSRCERIRTRKASLEELQSCHSEGYTLFFGTSQTHKAKLDSRKLA 709
Query: 457 NAQDENF------GIGYDCPPVPNMFELVST--IAGGSVT--AAKCLTMGIAD-IAINWC 603
NF G+G D V + + IA G+V A K T + + AI
Sbjct: 710 LIPKLNFTWLSCGGLGVDTDTVWHDIQSPGAVRIAAGAVIELAFKVATGELKNGFAIVRP 769
Query: 604 GGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVY 777
G HHA ++A GFC+ N I IA ++L+ K K IL +D DVHHGN Q ++ V
Sbjct: 770 PG-HHAETSQAMGFCFFNSIAIAAKQLRLKLKLNKILIIDWDVHHGNSTQKIFYEDPHVL 828
Query: 778 TLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+S H+ + G F+PGTG+ ++ GCG G GY+ N
Sbjct: 829 YISLHRHDNGNFFPGTGAPDESGCGAGLGYNVN 861
>UniRef50_Q0YKV4 Cluster: Histone deacetylase superfamily; n=1;
Geobacter sp. FRC-32|Rep: Histone deacetylase
superfamily - Geobacter sp. FRC-32
Length = 370
Score = 91.1 bits (216), Expect = 3e-17
Identities = 57/175 (32%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +1
Query: 364 PASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGG 543
PA+ L + H + YL +L+ D + + CP + F V AG
Sbjct: 99 PATVAQLQLVHEEKYLLNLEAACRQRDPLFMTPDN------HICP---DTFRAVLAAAGC 149
Query: 544 SVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVD 717
++ + L A A+ G HHA AEGFC+VN I +AIE ++ + N L VD
Sbjct: 150 ALALGETLLENGAGFALVRPPG-HHAGRKSAEGFCFVNHIALAIETIRQRQPAANFLVVD 208
Query: 718 LDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
DVHHGNG+ Y+ +V+ S H YP +G + + G G G G++CN L
Sbjct: 209 FDVHHGNGIDYIYYNDPTVFYYSLHGTPDHIYPHSGYVHETGHGPGAGFTCNITL 263
>UniRef50_UPI0000E87DA7 Cluster: histone deacetylase family protein;
n=1; Methylophilales bacterium HTCC2181|Rep: histone
deacetylase family protein - Methylophilales bacterium
HTCC2181
Length = 346
Score = 90.2 bits (214), Expect = 6e-17
Identities = 44/92 (47%), Positives = 58/92 (63%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA +++ GFC N+I IA L+ +F + IL VD DVHHGNG QD ++ SV+ S
Sbjct: 156 HHASSDKGMGFCIYNNIAIAARYLQQQFGLERILIVDFDVHHGNGTQDIFYEDPSVFYFS 215
Query: 787 FHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
H+ YPGTGS ++IG G GEGY+ N L
Sbjct: 216 VHQHP--LYPGTGSPQEIGSGKGEGYTLNVEL 245
>UniRef50_Q4T0M8 Cluster: Chromosome undetermined SCAF10929, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10929, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 903
Score = 89.4 bits (212), Expect = 1e-16
Identities = 40/90 (44%), Positives = 59/90 (65%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + GFCY N + IA ++L+ K IL VD DVHHGNG Q+ +++ SV +S
Sbjct: 553 HHADPSNPMGFCYFNSVAIAAKQLQHKLSVSKILIVDWDVHHGNGTQEVFYSDPSVLYIS 612
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+++ G F+PG+GS ++G G GEG++ N
Sbjct: 613 LHRYDNGNFFPGSGSPAEVGTGAGEGFNVN 642
>UniRef50_Q1NWE2 Cluster: Histone deacetylase superfamily; n=2;
delta proteobacterium MLMS-1|Rep: Histone deacetylase
superfamily - delta proteobacterium MLMS-1
Length = 349
Score = 89.4 bits (212), Expect = 1e-16
Identities = 51/129 (39%), Positives = 69/129 (53%), Gaps = 3/129 (2%)
Frame = +1
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEK 681
P +E AG +V A + + G D A HHA + + GFC N+I IA
Sbjct: 88 PRSYEAACLAAGAAVAAVELVAAGEVDNAFALVRPPGHHAEHAHSSGFCLFNNIAIAAHY 147
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDG 855
+ K FK IL D D+HHGNG Q A+ + V S H+F P F PG+G++ ++G G G
Sbjct: 148 ARQKLGFKRILIFDWDLHHGNGTQHAFDDSDQVLFFSTHQF-PCF-PGSGTLSEVGRGKG 205
Query: 856 EGYSCNFPL 882
EGY+ N PL
Sbjct: 206 EGYTINVPL 214
>UniRef50_Q08BS8 Cluster: Zgc:152701; n=9; Euteleostomi|Rep:
Zgc:152701 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1023
Score = 89.0 bits (211), Expect = 1e-16
Identities = 66/213 (30%), Positives = 108/213 (50%), Gaps = 14/213 (6%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYIS 456
P GR + + + ++ GL + + IR A+ E+L HS+ ++ L T+ +
Sbjct: 621 PEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHV--LLYGTNPLRQKLD 678
Query: 457 NAQDENF------GIGYDCPPVPNMFELVST--IAGGSVT--AAKCLTMGIAD-IAINWC 603
++ F GIG D + N S +A GSV K + + + A+
Sbjct: 679 SSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRP 738
Query: 604 GGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVY 777
G HHA + GFCY N + IA + L+ + IL VD DVHHGNG Q A+++ +V
Sbjct: 739 PG-HHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVL 797
Query: 778 TLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
LS H+++ G F+PG+G+ +++G G G G++ N
Sbjct: 798 YLSLHRYDDGNFFPGSGAPDEVGIGPGVGFNVN 830
>UniRef50_Q4UB07 Cluster: Histone deacetylase family protein,
putative; n=3; root|Rep: Histone deacetylase family
protein, putative - Theileria annulata
Length = 878
Score = 89.0 bits (211), Expect = 1e-16
Identities = 43/95 (45%), Positives = 57/95 (60%), Gaps = 5/95 (5%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA ++ GFC N++ IA L+ KF K + VD DVHHGNG QD ++ SV +S
Sbjct: 217 HHATPDKMMGFCIYNNVAIAARYLQHKFGLKRVAIVDWDVHHGNGTQDIFYDDNSVCFIS 276
Query: 787 FHKF---EPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
H++ E FYP TG ++IG G G GY+ N PL
Sbjct: 277 LHRYGDNEDSFYPYTGYCDEIGVGKGYGYNVNIPL 311
>UniRef50_Q17I08 Cluster: Histone deacetylase; n=1; Aedes aegypti|Rep:
Histone deacetylase - Aedes aegypti (Yellowfever
mosquito)
Length = 1112
Score = 89.0 bits (211), Expect = 1e-16
Identities = 66/213 (30%), Positives = 98/213 (46%), Gaps = 14/213 (6%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLY--LEHLKQIT--DIDD 444
P GR + + + GL ++ +RS A+ E+L HS+ + L QI +D
Sbjct: 700 PEHSGRLQSIWARLMETGLAARCDKLRSRKATQEELQSVHSEAHSLLFGTNQINRQKVDA 759
Query: 445 DYISNAQDENFGIGYDCPPVPNMFELVST--IAGGSVTAAKCLTMGIADIAINWC---GG 609
+S + G+G D N + +A G V C +I +
Sbjct: 760 SGVSFVRLGCGGVGVDLDTTWNEHHTAAAARMAAGCVIDL-CYKAAKGEIRNGFAVVRPP 818
Query: 610 WHHAHNNRAEGFCYVNDIVIAI----EKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVY 777
HHA N A GFC+ N I IA ++L + + +L VD DVHHGNG Q ++ SV
Sbjct: 819 GHHAEPNAAMGFCFFNSIAIAAKLLRQRLSSEIQRVLVVDWDVHHGNGTQQVFYDDPSVL 878
Query: 778 TLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
LS H+ + G F+PGTG + G G G G++ N
Sbjct: 879 YLSIHRHDDGNFFPGTGGPTECGAGPGLGFNVN 911
>UniRef50_Q9UQL6 Cluster: Histone deacetylase 5; n=141; Eumetazoa|Rep:
Histone deacetylase 5 - Homo sapiens (Human)
Length = 1122
Score = 89.0 bits (211), Expect = 1e-16
Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL+SK + IR A+ +++ HS+ LY +D
Sbjct: 705 PEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDS 764
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFELVSTI---AGGSVTAAKCLTMGIAD--I 588
+ + GIG D V N S + G + A + G
Sbjct: 765 KKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGF 824
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
AI G HHA + A GFC+ N + I + L+ K +L VD D+HHGNG Q A++
Sbjct: 825 AIIRPPG-HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYN 883
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
SV +S H+++ G F+PG+G+ E++G G G GY+ N
Sbjct: 884 DPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN 921
>UniRef50_UPI000051A1DA Cluster: PREDICTED: similar to HDAC4
CG1770-PB, isoform B; n=2; Apocrita|Rep: PREDICTED:
similar to HDAC4 CG1770-PB, isoform B - Apis mellifera
Length = 1048
Score = 88.6 bits (210), Expect = 2e-16
Identities = 67/213 (31%), Positives = 99/213 (46%), Gaps = 18/213 (8%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDDDYIS 456
GR + V + GL+ + IRS A+ E++ HS+ L+ + +D +S
Sbjct: 637 GRLQSVWARLSETGLLQRCDRIRSRKATLEEIQTCHSEAHALLFGTNPMNRQKLDVSKLS 696
Query: 457 NAQDENF------GIGYDCPPVPNMFELV--STIAGGSVTAAKCLTMGIADIAINWC--- 603
++F G+G D N + +A G V T + DI +
Sbjct: 697 QLPIKSFVRLPCGGVGVDSDTTWNELNTAPAARMAVGCVVDLAFKT-AMGDIKNGFAVVR 755
Query: 604 GGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVY 777
HHA N+A GFC+ N I IA L+ K + IL +D DVHHGNG Q ++ V
Sbjct: 756 PPGHHAETNQAMGFCFFNSIAIAARLLQQKLDIRKILILDWDVHHGNGTQQMFYDDPRVL 815
Query: 778 TLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
LS H+ + G F+PGTG + G G+G GY+ N
Sbjct: 816 YLSIHRHDEGNFFPGTGGPTECGAGEGLGYNVN 848
>UniRef50_UPI000069F4DB Cluster: Histone deacetylase 7a (HD7a).; n=3;
Xenopus tropicalis|Rep: Histone deacetylase 7a (HD7a). -
Xenopus tropicalis
Length = 893
Score = 88.6 bits (210), Expect = 2e-16
Identities = 64/218 (29%), Positives = 111/218 (50%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL + + IR A+ E+L H++ LY + +D+
Sbjct: 478 PEHAGRIQSIWSRLQERGLRNNCECIRGRKATLEELQSVHTETHVLLYGTNPLNRLKLDN 537
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD-I 588
++ + G+G D + N + A GSV A K + + +
Sbjct: 538 RKLAGILSQRMFVMLPCGGLGVDSDTIWNELHSSNAARWAAGSVIDLAFKVASRELKNGF 597
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWT 762
A+ G HHA + A GFC+ N + IA ++L+ + + IL VD DVHHGNG Q ++T
Sbjct: 598 ALVRPPG-HHADPSTAMGFCFFNSVAIAAKQLQLRRDVRKILIVDWDVHHGNGTQRVFYT 656
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+V +S H+ + G F+PG+G+ +++G G+GEG++ N
Sbjct: 657 DPNVLYISLHRHDDGNFFPGSGAADEVGAGNGEGFNVN 694
>UniRef50_UPI000065F55A Cluster: Histone deacetylase 7a (HD7a).;
n=1; Takifugu rubripes|Rep: Histone deacetylase 7a
(HD7a). - Takifugu rubripes
Length = 752
Score = 88.6 bits (210), Expect = 2e-16
Identities = 68/221 (30%), Positives = 112/221 (50%), Gaps = 20/221 (9%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYL-----EHLKQITD 435
R P GR + + + + GL + + IRS A+ E+L HS+ ++ L ++
Sbjct: 313 RHPEHAGRVQSIWSRLHERGLRGQCERIRSRKATLEELQSVHSEKHVLVFGTNPLNRLK- 371
Query: 436 IDDDYISNAQDENF-------GIGYDCPPVPNMFEL--VSTIAGGSVT--AAKCLTMGIA 582
+D+ ++ + G+G D V N S IA G VT A K +
Sbjct: 372 LDNRKLAGILSQRTFVMLPCGGVGVDIDTVWNEHHTSTASRIAAGCVTDLALKVAQGELK 431
Query: 583 D-IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDA 753
+ A+ G HHA ++ GFC+ N + IA ++L+ + IL VD D+HHGNG Q+A
Sbjct: 432 NGFAVVRPPG-HHATHSSPLGFCFFNSVAIAAKQLQQRLNVSKILIVDWDIHHGNGTQEA 490
Query: 754 YWTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+++ SV +S H+++ G F+PG G ++G G GEG++ N
Sbjct: 491 FYSDPSVLYISLHRYDGGNFFPGGGHPSEVGKGAGEGFNVN 531
>UniRef50_Q8IR37 Cluster: CG6170-PC, isoform C; n=7; Diptera|Rep:
CG6170-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1138
Score = 87.8 bits (208), Expect = 3e-16
Identities = 60/230 (26%), Positives = 110/230 (47%), Gaps = 10/230 (4%)
Frame = +1
Query: 226 RVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVF 393
+V Y +D +++ C P R + +H + + YGL+ ++K + A+ +++ +
Sbjct: 543 KVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLA 602
Query: 394 HSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTM 573
H+ ++ ++++ + + +A GI P F+ + AG + A +
Sbjct: 603 HTRAHVNTVRRLLGREPKELHDAA----GIYNSVYLHPRTFDCATLAAGLVLQAVDSVLR 658
Query: 574 GIADIAI-NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGV 744
G + I N HHA + GFC N++ IA + F + +L VD DVHHGNG
Sbjct: 659 GESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGT 718
Query: 745 QDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
Q + + V +S H++E G F+P G+ + +G G G G++ N P N
Sbjct: 719 QHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWN 768
Score = 83.4 bits (197), Expect = 7e-15
Identities = 69/224 (30%), Positives = 104/224 (46%), Gaps = 8/224 (3%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWD++ + R V R R + NL E + + S A+ +++ H++ + E
Sbjct: 130 LWDKEHYECPERFTRVLERCREL-NLTE------RCLELPSRSATKDEILRLHTEEHFER 182
Query: 418 LKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIAD--I 588
LK+ + I DD + E YD + P+ FEL +G ++ L G A +
Sbjct: 183 LKETSGIRDD----ERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGM 238
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWT 762
AI G HHA G+C+ N++ +A + K + IL +D DVHHG G Q ++
Sbjct: 239 AIIRPPG-HHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYN 297
Query: 763 TRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
V S H+FE G F+P IG G G GY+ N PLN
Sbjct: 298 DPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLN 341
>UniRef50_Q5KL48 Cluster: Histone deacetylase clr3, putative; n=1;
Filobasidiella neoformans|Rep: Histone deacetylase clr3,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 737
Score = 87.8 bits (208), Expect = 3e-16
Identities = 60/204 (29%), Positives = 97/204 (47%), Gaps = 8/204 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + + GLI ++K + +E + + H + + ++ + D I + ++
Sbjct: 97 RIKRIFTRLAEQGLIRRMKRLDFEEVKFEQVLLVHGEEMWDKVQATELLSDQQIQDMKEY 156
Query: 472 NFGIG-YDCPPVPNMFELVSTIAGGSVTAAK--CLTMGIADIAINWCGGWHHAHNNRAEG 642
+ Y C + L AGG + A + C AI G HHA N G
Sbjct: 157 YDQLSLYVCRETAHCARLS---AGGVIQACRSVCKNEVRNAFAIVRPPG-HHAEPNEHMG 212
Query: 643 FCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FY 813
FC+ N++ +A +++ G K +L +D DVHHGNG Q A+W V +S H+ E G FY
Sbjct: 213 FCFFNNVAVATREMQREGLAKKVLILDWDVHHGNGTQRAFWHDGDVLYMSLHRHEGGTFY 272
Query: 814 PGT--GSIEDIGCGDGEGYSCNFP 879
P + GS+ +G G+G G S N P
Sbjct: 273 PNSDFGSLNMVGDGEGVGKSVNIP 296
>UniRef50_A2AWS5 Cluster: Histone deacetylase 5; n=21;
Euarchontoglires|Rep: Histone deacetylase 5 - Mus
musculus (Mouse)
Length = 1030
Score = 87.0 bits (206), Expect = 6e-16
Identities = 38/90 (42%), Positives = 57/90 (63%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + A GFC+ N + I + L+ K +L VD D+HHGNG Q A++ SV +S
Sbjct: 740 HHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYNDPSVLYIS 799
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+++ G F+PG+G+ E++G G G GY+ N
Sbjct: 800 LHRYDNGNFFPGSGAPEEVGGGPGVGYNVN 829
>UniRef50_Q015Q9 Cluster: Histone deacetylase HDA110 isoform 2; n=2;
Ostreococcus|Rep: Histone deacetylase HDA110 isoform 2 -
Ostreococcus tauri
Length = 487
Score = 85.8 bits (203), Expect = 1e-15
Identities = 60/191 (31%), Positives = 96/191 (50%), Gaps = 7/191 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+V N + A GL S+ + +R A+ E+L HS ++ + D D + + E
Sbjct: 126 RHRVVVNEMRADGLESRCERLRCREATVEELERAHSKEHVAFVASAFDEDGESVQIMTGE 185
Query: 472 N-FGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWC---GGWHHAHNNRAE 639
N FG D + +A GSV+ A CL++ D+ + HHA +A
Sbjct: 186 NVFG---DDIFFTRHTAAGARMAAGSVSEA-CLSVCRGDVDRAYAVVRPPGHHAVCAQAM 241
Query: 640 GFCYVNDIVIAIEKLKGKF---KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGF 810
GFC+ N+ V+A + K ++ +D DVHHGNG+QD + S+ +S H++ F
Sbjct: 242 GFCFFNNAVVAARAAMAEHADVKKVVILDWDVHHGNGIQDLTFDDDSIMYVSLHRYGDDF 301
Query: 811 YPGTGSIEDIG 843
YPGTG+ ++G
Sbjct: 302 YPGTGAASEVG 312
>UniRef50_Q70I53 Cluster: Histone deacetylase-like amidohydrolase;
n=2; Proteobacteria|Rep: Histone deacetylase-like
amidohydrolase - Alcaligenes sp. (strain DSM 11172)
(Bordetella sp. (strain FB188))
Length = 369
Score = 85.8 bits (203), Expect = 1e-15
Identities = 63/199 (31%), Positives = 95/199 (47%), Gaps = 4/199 (2%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENF 477
R H L+ A G I L I + A+ D+ HS +LE++K+++++ +
Sbjct: 44 RRFHELVCASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMM 103
Query: 478 GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMG--IADIAINWCGGWHHAHNNRAEGFCY 651
G G E+ AGG+V + + G A A+ G HHA +N A GFC
Sbjct: 104 GNGG--------LEIARLSAGGAVELTRRVATGELSAGYALVNPPG-HHAPHNAAMGFCI 154
Query: 652 VNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTG 825
N+ +A + + + +D DVHHGNG QD +W SV T+S H+ F P +G
Sbjct: 155 FNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTISLHQ-HLCFPPDSG 213
Query: 826 SIEDIGCGDGEGYSCNFPL 882
+ G G+G GY+ N PL
Sbjct: 214 YSTERGAGNGHGYNINVPL 232
>UniRef50_UPI0000F2108C Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 673
Score = 85.4 bits (202), Expect = 2e-15
Identities = 38/90 (42%), Positives = 57/90 (63%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + GFC+ N + IA ++L+ K IL VD DVHHGNG Q+ ++ SV +S
Sbjct: 391 HHADPSNPMGFCFFNSVAIAAKQLQQKLSASKILIVDWDVHHGNGTQEIFYNDPSVLYIS 450
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+++ G F+PG+G ++G G GEG++ N
Sbjct: 451 LHRYDNGNFFPGSGGPAEVGSGAGEGFNVN 480
>UniRef50_Q0LS19 Cluster: Histone deacetylase superfamily; n=1;
Caulobacter sp. K31|Rep: Histone deacetylase superfamily
- Caulobacter sp. K31
Length = 379
Score = 84.6 bits (200), Expect = 3e-15
Identities = 64/199 (32%), Positives = 92/199 (46%), Gaps = 4/199 (2%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENF 477
R NL++ GL+ KL I + A+ ++ H+ +H+ QI I + + +
Sbjct: 44 RRFRNLVDVSGLLKKLVDIPARLATGLEIGRVHTS---DHINQIK-IMSGFPTGGEP--- 96
Query: 478 GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCG-GWHHAHNNRAEGFCYV 654
G D P FE+ S AGG++ A + G D A HH+ +R+ GFC
Sbjct: 97 --GDDAPVPYGAFEIASLAAGGAIAAVDAVMSGEVDNAYALLRPAGHHSRPDRSMGFCIF 154
Query: 655 NDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-GTG 825
++ IA L K I YVD DVHHGNG Q A + T+S H + YP G
Sbjct: 155 SNAAIAGRHLLDFHNVKRIAYVDWDVHHGNGTQAALYNEPRALTISIH--QDRLYPVDDG 212
Query: 826 SIEDIGCGDGEGYSCNFPL 882
++ IG G EG + N PL
Sbjct: 213 FVDQIGEGAAEGTNLNIPL 231
>UniRef50_Q569T0 Cluster: MGC115178 protein; n=5; Tetrapoda|Rep:
MGC115178 protein - Xenopus laevis (African clawed frog)
Length = 683
Score = 84.2 bits (199), Expect = 4e-15
Identities = 66/224 (29%), Positives = 105/224 (46%), Gaps = 8/224 (3%)
Frame = +1
Query: 238 LWDEKLVKEC-IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
LWD+ EC I +P R + ++ Y L+ + + A+ E++ + HS YL+
Sbjct: 19 LWDDP---ECSIEVPE---RLSSSYKRLQDYDLVKRCIQLPVREATDEEITLVHSHDYLQ 72
Query: 415 HLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKC-LTMGIAD-I 588
+K +++ + + + Y N F GG++ LT + + +
Sbjct: 73 VVKSTQTMNEKELKEISQKYTAVFYH----QNSFRCAKLSLGGTLQLVDAILTREVQNGM 128
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
AI G HH+ N+ GFC N++ IA E K K+K IL VD DVHHG G+Q +
Sbjct: 129 AIVRPPG-HHSQRNQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEE 187
Query: 763 TRSVYTLSFHKFE-PGFYP--GTGSIEDIGCGDGEGYSCNFPLN 885
SV S+H++E F+P + IG G G G++ N P N
Sbjct: 188 DPSVLYFSWHRYEHKTFWPYLRESDYDVIGRGKGTGFNINLPWN 231
>UniRef50_A6Q2Z0 Cluster: Acetoin utilization protein; n=1;
Nitratiruptor sp. SB155-2|Rep: Acetoin utilization
protein - Nitratiruptor sp. (strain SB155-2)
Length = 302
Score = 84.2 bits (199), Expect = 4e-15
Identities = 52/150 (34%), Positives = 76/150 (50%), Gaps = 5/150 (3%)
Frame = +1
Query: 445 DYISNAQDEN--FGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMG-IADIAINWCGGWH 615
D++ +A + F + D P +E+ S AG + + G I +N H
Sbjct: 62 DWVEHAYENGYRFILNEDTLLTPRSYEVASFAAGSTKSIVDGFAEGKIQRAFLNLRPPAH 121
Query: 616 HAHNNRAEGFCYVNDIV-IAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
HA +GFC N++ +A K F+ +L +D DVHHGNG QD ++ +V+ S H
Sbjct: 122 HAERRTGQGFCIFNNVAFMARYAQKRGFEKVLIIDFDVHHGNGTQDIFYEDDTVFYFSTH 181
Query: 793 KFEPGFYP-GTGSIEDIGCGDGEGYSCNFP 879
E YP TGS E+IG G G+GY+CN P
Sbjct: 182 --ERNNYPYFTGSEEEIGEGRGKGYNCNRP 209
>UniRef50_A0L9T2 Cluster: Histone deacetylase superfamily; n=3;
Proteobacteria|Rep: Histone deacetylase superfamily -
Magnetococcus sp. (strain MC-1)
Length = 327
Score = 84.2 bits (199), Expect = 4e-15
Identities = 52/186 (27%), Positives = 85/186 (45%), Gaps = 2/186 (1%)
Frame = +1
Query: 331 LISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPN 510
L SK+ + A E L+ FH+ Y+E +K+ +D + ++ + D P P
Sbjct: 46 LSSKVVIADPVMAQPEQLHSFHTPQYVELVKRCSDAGEGFLDHG---------DTPAFPG 96
Query: 511 MFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKG 690
++E + + G +V AA+ + G HHA + A GFC ND + ++ L+
Sbjct: 97 IYEAAAYVVGSAVAAAEQIMQQRFRRIFIPIAGLHHAQPDVAGGFCVFNDAAVVVKHLRK 156
Query: 691 K--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGY 864
+ K I YVD+D HHG+GV + + H+ YP GS ++ G G G
Sbjct: 157 QHGIKKIAYVDIDAHHGDGVFYPFEADPHLIFADIHEDGRYLYPWCGSEDETGVGPAYGT 216
Query: 865 SCNFPL 882
N P+
Sbjct: 217 KVNIPM 222
>UniRef50_A3CT27 Cluster: Histone deacetylase superfamily; n=2;
Methanoculleus marisnigri JR1|Rep: Histone deacetylase
superfamily - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 330
Score = 84.2 bits (199), Expect = 4e-15
Identities = 38/90 (42%), Positives = 54/90 (60%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
HHA +RA GFC N++ +A K + VD D+HHGNG ++A++T+ V+ S H
Sbjct: 120 HHAAPDRAMGFCLFNNVAVATAKALLSIGRVAVVDWDLHHGNGTEEAFYTSDRVFYCSVH 179
Query: 793 KFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+ G +PGTG E+ G G G GY+ N PL
Sbjct: 180 --QAGIFPGTGWPEERGAGPGAGYTVNVPL 207
>UniRef50_Q8GXJ1 Cluster: Histone deacetylase 15; n=11;
Magnoliophyta|Rep: Histone deacetylase 15 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 552
Score = 84.2 bits (199), Expect = 4e-15
Identities = 41/92 (44%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIA--IEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA A GFC N+ +A + + G K +L VD DVHHGNG Q+ + +SV +S
Sbjct: 276 HHAGVRHAMGFCLHNNAAVAALVAQAAGA-KKVLIVDWDVHHGNGTQEIFEQNKSVLYIS 334
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCNFP 879
H+ E G FYPGTG+ +++G GEGY N P
Sbjct: 335 LHRHEGGIFYPGTGAADEVGSNGGEGYCVNVP 366
>UniRef50_O67877 Cluster: Acetoin utilization protein; n=3;
Bacteria|Rep: Acetoin utilization protein - Aquifex
aeolicus
Length = 310
Score = 83.8 bits (198), Expect = 5e-15
Identities = 59/227 (25%), Positives = 104/227 (45%), Gaps = 7/227 (3%)
Frame = +1
Query: 226 RVAYLWDEKLVK-ECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD 402
+V +++D+ +K + P R + +E G+ L ++ A E++ + H
Sbjct: 3 KVGFIYDDIYLKHDWPEHPENKNRLISILEHVEKSGIKKALIDVKPRRAKVEEVALNHDP 62
Query: 403 LYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA 582
Y++ + Y+ D P+ +++ GG + + G
Sbjct: 63 AYIQEIHDFCKSGGGYLDP----------DTYATPDTYDVALYAVGGVLEGIDRILSGEL 112
Query: 583 DIAINWCG---GWHHAHNNRAEGFCYVNDIVIA---IEKLKGKFKNILYVDLDVHHGNGV 744
D A +C HHA +A GFC N++ I + K+KG K + +D D HHGNG
Sbjct: 113 DRA--FCAVRPPGHHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNK-VFIIDFDAHHGNGT 169
Query: 745 QDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPLN 885
Q +++ +V+ S H++ FYPGTGS ++ G G G GY+ N P++
Sbjct: 170 QKSFYEDDTVFYFSTHEYP--FYPGTGSEDERGAGKGYGYTYNVPMS 214
>UniRef50_A3JI99 Cluster: Putative aminohydrolase; n=1; Marinobacter
sp. ELB17|Rep: Putative aminohydrolase - Marinobacter
sp. ELB17
Length = 344
Score = 83.4 bits (197), Expect = 7e-15
Identities = 37/91 (40%), Positives = 53/91 (58%), Gaps = 1/91 (1%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
HHA + A GFCY+N+ I E L+ KF+ I +D D+HHG G+Q+ ++ + V S H
Sbjct: 160 HHARKSAAGGFCYLNNAAIIAEHLRQKFQKIAIIDTDMHHGQGIQEIFYDRKDVLYTSVH 219
Query: 793 KFEPGFYP-GTGSIEDIGCGDGEGYSCNFPL 882
FYP G + G G+G GY+ NFP+
Sbjct: 220 GNPINFYPVVAGHEHERGYGEGYGYNINFPM 250
>UniRef50_Q8I9J6 Cluster: Histone deacetylase dHDAC4 isoform b; n=7;
Sophophora|Rep: Histone deacetylase dHDAC4 isoform b -
Drosophila melanogaster (Fruit fly)
Length = 1255
Score = 83.4 bits (197), Expect = 7e-15
Identities = 40/91 (43%), Positives = 55/91 (60%), Gaps = 4/91 (4%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF---KNILYVDLDVHHGNGVQDAYWTTRSVYTL 783
HHA N A GFC+ N I IA + L+ + + IL VD DVHHGNG Q A++ + + L
Sbjct: 970 HHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQSPDILYL 1029
Query: 784 SFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
S H+ + G F+PGTG + G G G G++ N
Sbjct: 1030 SIHRHDDGNFFPGTGGPTECGSGAGLGFNVN 1060
>UniRef50_O17323 Cluster: Histone deacetylase 4; n=3;
Caenorhabditis|Rep: Histone deacetylase 4 -
Caenorhabditis elegans
Length = 816
Score = 83.0 bits (196), Expect = 9e-15
Identities = 36/96 (37%), Positives = 60/96 (62%), Gaps = 5/96 (5%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF----KNILYVDLDVHHGNGVQDAYWTTRSVYT 780
HHA + +A GFC+ N++ +A++ L+ K+ I +D DVHHGNG Q ++ +V
Sbjct: 554 HHAEHEQAMGFCFFNNVAVAVKVLQTKYPAQCAKIAIIDWDVHHGNGTQLSFENDPNVLY 613
Query: 781 LSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCNFPLN 885
+S H+ + G F+PGTGS+ ++G D +G + N P +
Sbjct: 614 MSLHRHDKGNFFPGTGSVTEVGKNDAKGLTVNVPFS 649
>UniRef50_Q02A43 Cluster: Histone deacetylase superfamily; n=1;
Solibacter usitatus Ellin6076|Rep: Histone deacetylase
superfamily - Solibacter usitatus (strain Ellin6076)
Length = 305
Score = 82.6 bits (195), Expect = 1e-14
Identities = 50/129 (38%), Positives = 67/129 (51%), Gaps = 5/129 (3%)
Frame = +1
Query: 490 DCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD-IAINWCGGWHHAHNNRAEGFCYVNDIV 666
+ P M E AGGS+ AA+ + + D I N GG+HHA EGFC +ND+
Sbjct: 81 EIPYSRQMVEAFWLAAGGSILAAR---LALQDGIGFNIGGGFHHAFPGHGEGFCAINDVA 137
Query: 667 IAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIE-- 834
IA+ +L+ K + VD DVHHGNG + +SV+TLS H+F YP +
Sbjct: 138 IAVRRLQADRLIKRAMVVDCDVHHGNGTAAIFTDDQSVFTLSIHQFNN--YPSEKPLSSL 195
Query: 835 DIGCGDGEG 861
DI DG G
Sbjct: 196 DIHLTDGIG 204
>UniRef50_Q8TWH9 Cluster: Predicted deacetylase; n=1; Methanopyrus
kandleri|Rep: Predicted deacetylase - Methanopyrus
kandleri
Length = 352
Score = 82.6 bits (195), Expect = 1e-14
Identities = 47/137 (34%), Positives = 66/137 (48%), Gaps = 3/137 (2%)
Frame = +1
Query: 481 IGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVN 657
I D P ++ AGGSV A + + G D A HHA +A GFCY N
Sbjct: 79 IDLDTAVAPETYDQALLAAGGSVLAVELVVRGEYDTAFAMVRPPGHHAGRAKAAGFCYFN 138
Query: 658 DIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
+ IA E + ++ +D D HHG+G Q+ ++ V +S H+ YPGTG
Sbjct: 139 NAAIAAEYAIRELGVDSVAILDWDAHHGDGTQEIFYDRDDVLYVSIHQDGRTLYPGTGFP 198
Query: 832 EDIGCGDGEGYSCNFPL 882
+ G G GEGY+ N P+
Sbjct: 199 YEAGEGPGEGYTVNIPV 215
>UniRef50_Q2FQ17 Cluster: Histone deacetylase superfamily; n=1;
Methanospirillum hungatei JF-1|Rep: Histone deacetylase
superfamily - Methanospirillum hungatei (strain JF-1 /
DSM 864)
Length = 322
Score = 82.6 bits (195), Expect = 1e-14
Identities = 47/119 (39%), Positives = 65/119 (54%), Gaps = 3/119 (2%)
Frame = +1
Query: 535 AGGSVTAAKCLTMGIADIA--INWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNI 705
A G +TA + L A A +N G HH + +R GFCY+N+ I L+ + I
Sbjct: 82 AFGCLTAGEMLIQDEAQNAFVLNRPPG-HHTYADRGGGFCYLNNAAILARYLQMHGMEKI 140
Query: 706 LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+ +D D HHGNG + ++ SV S H+ P YPGTG I+D G G GEGY+ N P+
Sbjct: 141 MIIDWDAHHGNGTESIFYDDPSVLYTSIHQ-SP-LYPGTGEIQDTGVGQGEGYTINIPV 197
>UniRef50_O30107 Cluster: Uncharacterized protein AF_0130; n=2;
Euryarchaeota|Rep: Uncharacterized protein AF_0130 -
Archaeoglobus fulgidus
Length = 359
Score = 82.6 bits (195), Expect = 1e-14
Identities = 60/204 (29%), Positives = 97/204 (47%), Gaps = 7/204 (3%)
Frame = +1
Query: 292 RARLVHNL--IEAYGLISKLKVIRSSP--ASYEDLNVFHSDLYLEHLKQITDIDDDYISN 459
R RL + + + G+ +++ P AS ED+ H++ Y+ L+
Sbjct: 24 RERLAYTMDQLREEGIFESERIVLLEPFKASLEDVLEVHTEEYVRFLEM----------- 72
Query: 460 AQDENFGI-GYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNR 633
+ + GI +D +F+ AGG++ AA+ + + A HHA
Sbjct: 73 -ESKKGGIIDFDTNIPVGVFDRALLAAGGAIRAAQAVLNKECENAFAMIRPPGHHAKPYI 131
Query: 634 AEGFCYVNDIVIAIE-KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGF 810
GFCY+N++ I ++ LK F+ I +D D HHG+G Q+ ++ V +S H+
Sbjct: 132 GAGFCYLNNMAIMVKWLLKQGFERIAILDWDAHHGDGTQEIFYNDDRVLFISTHQMP--L 189
Query: 811 YPGTGSIEDIGCGDGEGYSCNFPL 882
YPGTG E+ G G GEGY+ N PL
Sbjct: 190 YPGTGYPEECGTGKGEGYTVNIPL 213
>UniRef50_Q8RX28 Cluster: Histone deacetylase 5; n=4;
Magnoliophyta|Rep: Histone deacetylase 5 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 660
Score = 82.6 bits (195), Expect = 1e-14
Identities = 65/206 (31%), Positives = 91/206 (44%), Gaps = 10/206 (4%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R++ ++ G+ + V+ SS A + L + H+ ++ +K I+ DY N
Sbjct: 52 RIRVIWEKLQLAGVSQRCVVLGSSKAEDKHLQLVHTKDHVNLVKSISTKQKDYRRNRIAS 111
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGF 645
Y E AG V A+ + G D AI G HHA + A GF
Sbjct: 112 QLNSIY---LNGGSSEAAYLAAGSVVKLAEKVAEGELDCGFAIVRPPG-HHAEADEAMGF 167
Query: 646 CYVNDIVIAIEKLKGK-----FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE-PG 807
C N++ +A L + K IL VD DVHHGNG Q +W V S H+ E G
Sbjct: 168 CLFNNVAVAASFLLNERPDLGVKKILIVDWDVHHGNGTQKMFWKDPRVLFFSVHRHEYGG 227
Query: 808 FYPG--TGSIEDIGCGDGEGYSCNFP 879
FYP G +G G GEG++ N P
Sbjct: 228 FYPAGDDGDYNMVGEGPGEGFNINVP 253
>UniRef50_UPI0000DB73BE Cluster: PREDICTED: similar to HDAC6
CG6170-PA, isoform A; n=2; Apis mellifera|Rep:
PREDICTED: similar to HDAC6 CG6170-PA, isoform A - Apis
mellifera
Length = 1019
Score = 82.2 bits (194), Expect = 2e-14
Identities = 66/209 (31%), Positives = 98/209 (46%), Gaps = 10/209 (4%)
Frame = +1
Query: 295 ARLVHNL--IEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
ARL+ L E GLIS+ K+I AS ++ + HS ++ LK D I+N
Sbjct: 110 ARLIRVLQRCEELGLISRCKLITPRLASENEILIKHSQEQIDILKSTDGCTD--INNL-- 165
Query: 469 ENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAE 639
E YD + P+ + L G ++ + + G +AI G HHA +
Sbjct: 166 ELLSSKYDAIYIHPSTYRLSLLAVGSTINLVESICKGEIQNGMAIIRPPG-HHAMKSEYC 224
Query: 640 GFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-F 810
G+C+ N++ IA EK+ IL VD DVHHG Q ++ V S H++E G F
Sbjct: 225 GYCFFNNVAIAAEKVLCNNLASKILIVDWDVHHGQATQQMFYDNPQVIYFSIHRYENGEF 284
Query: 811 YPG--TGSIEDIGCGDGEGYSCNFPLNXL 891
+P + +G GEGY+ N PLN +
Sbjct: 285 WPNLRESNFHFVGDDLGEGYNFNVPLNKI 313
Score = 73.3 bits (172), Expect = 8e-12
Identities = 61/230 (26%), Positives = 107/230 (46%), Gaps = 10/230 (4%)
Frame = +1
Query: 226 RVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVF 393
+V ++D++++K P R +++ + Y L+ + V + A+ E+L +
Sbjct: 465 KVCIVYDDRMLKHYDISDANHPEKPHRINIIYKKFQEYNLLDRSFVQQGRSATKEELLLV 524
Query: 394 HSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTM 573
H+ Y++ +K ++ + Q E + Y P + +ST + V
Sbjct: 525 HTKEYIDKIKNTKNLKSKELKK-QAETYNSVYLHPETWSS-ACISTGSLLQVVDNVLNGE 582
Query: 574 GIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF---KNILYVDLDVHHGNGV 744
+ IAI G HHA + A GFC N++ IA K +F K +L VD DVH+GNG
Sbjct: 583 SQSGIAIIRPPG-HHATEDAACGFCIFNNVAIAA-KYAIEFHHVKRVLIVDWDVHYGNGT 640
Query: 745 QDAYWTTRSVYTLSFHKFEPG-FYPGT--GSIEDIGCGDGEGYSCNFPLN 885
Q + V +S H+++ G F+P + + +G GEG++ N P N
Sbjct: 641 QSIFEEDSKVLYISIHRYDNGSFFPNSKRANYSYVGSESGEGFTVNIPWN 690
>UniRef50_Q8F7M9 Cluster: Histone deacetylase family protein; n=4;
Leptospira|Rep: Histone deacetylase family protein -
Leptospira interrogans
Length = 313
Score = 82.2 bits (194), Expect = 2e-14
Identities = 38/91 (41%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSF 789
HHA +NR GFC +N++ I L+ FK I +D DVHHGNG Q+ ++ +++ LS
Sbjct: 125 HHAEHNRIMGFCMLNNVAITARYLQNNGFKKIFIIDWDVHHGNGTQEIFYEDPNIFYLSI 184
Query: 790 HKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
H+F FYP TG + G G G G + N P+
Sbjct: 185 HQFP--FYPMTGLATETGKGKGIGTTKNIPM 213
>UniRef50_Q62HN7 Cluster: Acetylpolyamine aminohydrolase; n=53;
Proteobacteria|Rep: Acetylpolyamine aminohydrolase -
Burkholderia mallei (Pseudomonas mallei)
Length = 340
Score = 82.2 bits (194), Expect = 2e-14
Identities = 34/91 (37%), Positives = 52/91 (57%), Gaps = 1/91 (1%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
HHA + A GFCY+N+ IA + L+ + + +D D+HHG G+Q+ ++ R V +S H
Sbjct: 155 HHARVDAAGGFCYLNNAAIAAQALRARHARVAVLDTDMHHGQGIQEIFYARRDVLYVSIH 214
Query: 793 KFEPGFYPGTGSIED-IGCGDGEGYSCNFPL 882
FYP +D G G+G GY+ N P+
Sbjct: 215 GDPTNFYPAVAGFDDERGAGEGLGYNVNLPM 245
>UniRef50_A3H8X1 Cluster: Histone deacetylase superfamily; n=1;
Caldivirga maquilingensis IC-167|Rep: Histone
deacetylase superfamily - Caldivirga maquilingensis
IC-167
Length = 346
Score = 82.2 bits (194), Expect = 2e-14
Identities = 43/118 (36%), Positives = 64/118 (54%), Gaps = 7/118 (5%)
Frame = +1
Query: 550 TAAKCLTMGIADIAINWCGGWHHA-HNNRA-----EGFCYVNDI-VIAIEKLKGKFKNIL 708
TA L G+ + + HHA RA +GFC +N+ +I+ LKG +
Sbjct: 97 TAVNLLKSGVRYVYLPLRPPGHHAGFRGRALMASTQGFCILNNAAIISSLLLKGGASRVA 156
Query: 709 YVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+D+D HHGNG Q+ ++ T V+ +S H+ YPGTG + + G GDGEG++ N PL
Sbjct: 157 VLDIDAHHGNGTQEIFYNTSRVFYISTHQDPRTLYPGTGYVNETGVGDGEGFNMNIPL 214
>UniRef50_A3ZYN7 Cluster: Acetoin utilization protein; n=3;
Planctomycetaceae|Rep: Acetoin utilization protein -
Blastopirellula marina DSM 3645
Length = 311
Score = 81.8 bits (193), Expect = 2e-14
Identities = 41/92 (44%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA GFC N + IA + K +L VD DVHHGNG QDA+W + LS
Sbjct: 122 HHATPTMPMGFCLFNSVAIAAQYALSKLDLDRVLIVDWDVHHGNGTQDAFWESERAAFLS 181
Query: 787 FHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
H++ FYPGTG +IG G GY+ N PL
Sbjct: 182 IHRYP--FYPGTGDTLEIGQRAGLGYTRNLPL 211
>UniRef50_A7SSG8 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 369
Score = 81.8 bits (193), Expect = 2e-14
Identities = 63/227 (27%), Positives = 109/227 (48%), Gaps = 10/227 (4%)
Frame = +1
Query: 235 YLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
Y++ L+ +P GR H + YGL+ + I S A+ EDL HS +++
Sbjct: 19 YVYINTLICSLYEVPDRIGRPYEKH---KEYGLLDRCYKIPSRHATEEDLLCLHSKEHID 75
Query: 415 HLKQITDIDDDYISNAQDENFGI-----GYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI 579
+K D+ + N +E I YDC + L + + ++K ++ I
Sbjct: 76 KMKSTQDMKPRDLFNLGEEYDSIYMSKDVYDCALLSCGCTLAAVEHVATNKSSK-HSIHI 134
Query: 580 ADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDA 753
+ G HHA + A G+C+ N++ IA + + ++ + IL VD D+HHGNG Q+
Sbjct: 135 NQLFFLRPPG-HHADADSAMGYCFFNNVAIAAKLAQQRWGMQRILIVDWDIHHGNGTQNL 193
Query: 754 YWTTRSVYTLSFHKFE-PGFYP--GTGSIEDIGCGDGEGYSCNFPLN 885
+ + SV S H+++ FYP + + +G G G+G++ N P N
Sbjct: 194 FESDPSVLYFSLHRYDHANFYPFSAQANYDIVGKGQGKGFNVNVPWN 240
>UniRef50_Q9UBN7 Cluster: Histone deacetylase 6; n=38; Eutheria|Rep:
Histone deacetylase 6 - Homo sapiens (Human)
Length = 1215
Score = 81.8 bits (193), Expect = 2e-14
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 539 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 594
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 595 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 653
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + SV +S H+++ G F+P G+ IG G G++ N N
Sbjct: 654 NGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 706
Score = 72.1 bits (169), Expect = 2e-11
Identities = 64/225 (28%), Positives = 105/225 (46%), Gaps = 9/225 (4%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWD+ + RL A+ + +L+ GL+ + ++ A E+L + HS Y++
Sbjct: 100 LWDDSFPEGPERLHAI--KEQLIQE-----GLLDRCVSFQARFAEKEELMLVHSLEYID- 151
Query: 418 LKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIA---D 585
L + T Y++ + YD + PN + + +A GSV +G
Sbjct: 152 LMETTQ----YMNEGELRVLADTYDSVYLHPNSYSC-ACLASGSVLRLVDAVLGAEIRNG 206
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYW 759
+AI G HHA ++ +G+C N + +A + K + + +L VD DVHHG G Q +
Sbjct: 207 MAIIRPPG-HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFD 265
Query: 760 TTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
SV S H++E G F+P + G G G+GY+ N P N
Sbjct: 266 QDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 310
>UniRef50_UPI0001555A7F Cluster: PREDICTED: similar to histone
deacetylase 6, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to histone deacetylase
6, partial - Ornithorhynchus anatinus
Length = 803
Score = 81.4 bits (192), Expect = 3e-14
Identities = 56/194 (28%), Positives = 95/194 (48%), Gaps = 8/194 (4%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + + AS ++L + HS Y+E ++ + + + + + E + Y P
Sbjct: 334 GLTQRCRALPARLASDQELLLCHSPEYVEQMRATSGLKPREL-HREGERYNSIYIAP--- 389
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIA--DIAINWCGGWHHAHNNRAEGFCYVNDIVIAI-- 675
F AG + + + + G +AI G HHA + A GFC+ N + +A
Sbjct: 390 RSFHCAQLAAGSACSLVEAVLDGQVRNGVAIVRPPG-HHAERDTACGFCFFNSVAVAARH 448
Query: 676 -EKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGT--GSIEDIG 843
++L G+ +L +D DVHHGNG Q + SV +S H+++ G F+P + G G
Sbjct: 449 AQQLAGRPLRVLILDWDVHHGNGTQHMFEEDPSVLYVSLHRYDHGSFFPTSEDGDSSQTG 508
Query: 844 CGDGEGYSCNFPLN 885
G GEG++ N P N
Sbjct: 509 RGRGEGFTLNVPWN 522
Score = 62.9 bits (146), Expect = 1e-08
Identities = 49/185 (26%), Positives = 81/185 (43%), Gaps = 8/185 (4%)
Frame = +1
Query: 355 RSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVST 531
++ PA+ E+L HS +L+ ++ + ++ + D YD + PN +
Sbjct: 46 QARPATQEELLRVHSQEFLKLMESTQQMSEEELRALADT-----YDSVFLHPNSYACARL 100
Query: 532 IAGGSVTAAKCLTMGIA--DIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK-- 699
G + + G +A+ G HHA R +G+C N + ++ + K +
Sbjct: 101 ATGTVLQLVDMVMAGEVRNGLAVVRPPG-HHAQRERMDGYCMFNHLAVSARHAQEKHQVE 159
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGTGSIE--DIGCGDGEGYSC 870
+L VD DVHHG G Q + SV S H++E F+P + G G G GY+
Sbjct: 160 RVLIVDWDVHHGQGTQRIFDQDSSVLYFSIHRYEHARFWPHLPESDWRAAGIGRGRGYTI 219
Query: 871 NFPLN 885
N P N
Sbjct: 220 NVPWN 224
>UniRef50_Q5LRW9 Cluster: Acetylpolyamine aminohydrolase; n=7;
Rhodobacteraceae|Rep: Acetylpolyamine aminohydrolase -
Silicibacter pomeroyi
Length = 341
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/131 (33%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Frame = +1
Query: 493 CPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIA 672
CP +E A ++T A + G + HHA + A GFC++N+ IA
Sbjct: 117 CPIAEGTWEAAYWSAQSAITGADLIIQGERSAYVLSRPPGHHAFGDLAGGFCFLNNSAIA 176
Query: 673 IEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-GTGSIEDIGCG 849
E+L+ +D+DVHHGNG Q ++ V T+S H FYP G ++ G G
Sbjct: 177 AERLRAAGLRPAILDIDVHHGNGTQGIFYERDDVLTVSIHADPARFYPFFWGHAQERGAG 236
Query: 850 DGEGYSCNFPL 882
G GY+ N PL
Sbjct: 237 RGLGYNLNLPL 247
>UniRef50_Q2LVD3 Cluster: Histone deacetylase family protein; n=1;
Syntrophus aciditrophicus SB|Rep: Histone deacetylase
family protein - Syntrophus aciditrophicus (strain SB)
Length = 350
Score = 81.4 bits (192), Expect = 3e-14
Identities = 50/180 (27%), Positives = 85/180 (47%), Gaps = 3/180 (1%)
Frame = +1
Query: 355 RSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTI 534
R ++D+ + + HL + D + S A+ E + D P ++
Sbjct: 38 RDMQGRFQDVPAREARMDELHLIHLPDYVNRVASTARMEYSCLDPDTDTSPGSYKAALLA 97
Query: 535 AGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNI 705
AGG A + G D A HHA +R++GFC N++ I + + I
Sbjct: 98 AGGLCEAISMVASGKLDNAFALVRPPGHHAEADRSKGFCLFNNVAIGARYAQTALHLQRI 157
Query: 706 LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPLN 885
L +D D+HHGNG Q ++ T S+ S H++ ++PGTG+ +++G G G++ N PL+
Sbjct: 158 LIIDWDLHHGNGTQHSFETDPSILYFSTHQYP--YFPGTGACDEVGRRTGLGFTVNVPLS 215
>UniRef50_A6FY71 Cluster: Histone deacetylase superfamily protein;
n=1; Plesiocystis pacifica SIR-1|Rep: Histone
deacetylase superfamily protein - Plesiocystis pacifica
SIR-1
Length = 623
Score = 81.4 bits (192), Expect = 3e-14
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL+ V+R +PA++ L H YLE L+ ++ FG P
Sbjct: 63 GLVGPECVVRPTPAAFVKLARVHDQAYLERLESAA---------VMEQAFGEVVPPGPAT 113
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK 687
+ EL + GG++ AA+ +A+N GG+HHA +RA GFC +ND+ +AI +L+
Sbjct: 114 AIVELQRAMVGGTMLAARAAWRR-HKLAVNLGGGFHHARRDRAGGFCLLNDVAVAIAELR 172
Query: 688 --GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
G I VDLD+H G+G + + SV+T S H
Sbjct: 173 ASGFTGPISVVDLDLHDGDGTRLMFADDPSVWTFSIH 209
>UniRef50_Q569C4 Cluster: Histone deacetylase 10; n=5; Mammalia|Rep:
Histone deacetylase 10 - Rattus norvegicus (Rat)
Length = 588
Score = 81.4 bits (192), Expect = 3e-14
Identities = 54/193 (27%), Positives = 91/193 (47%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ +D + + + + + P
Sbjct: 42 GLEERCQCLSVCEASEEELGLVHSPEYIALVQKTQTLDKEELHTLSKQYDAVYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG ++ + G +A+ G HH+ A GFC N++ IA
Sbjct: 98 DTFHCARLAAGAALRLVDAVLTGAVHNGVALVRPPG-HHSQRAAANGFCVFNNVAIAARH 156
Query: 682 LKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K+ + IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKYGLQRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHGNFWPFLPESDADTVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G+G++ N P N
Sbjct: 217 GRGQGFTVNLPWN 229
>UniRef50_Q6AKN4 Cluster: Putative uncharacterized protein; n=1;
Desulfotalea psychrophila|Rep: Putative uncharacterized
protein - Desulfotalea psychrophila
Length = 341
Score = 81.0 bits (191), Expect = 4e-14
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Frame = +1
Query: 343 LKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFEL 522
L++I A+ E + HS+ YL +++ + F D +
Sbjct: 43 LRIITPHEANTETIEKVHSNFYLSQIREHA---------LKSNPFSYDQDTYLMQQSLAT 93
Query: 523 VSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF 696
AGG + A + G D A+ G HHA R GFC +N+I I + L+ +
Sbjct: 94 AQLAAGGCLEIADQIMNGEIDHGFALIRPPG-HHAEPGRGMGFCILNNIAITAKYLQTHY 152
Query: 697 K--NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSC 870
IL +D DVHHGNG Q+ ++ T V +S H + +P +G+ E+IG G GY+
Sbjct: 153 NLSRILIIDFDVHHGNGTQEVFYDTNQVLFVSIH--QKNLFPFSGAPEEIGNEQGRGYNI 210
Query: 871 NFPLN 885
N P++
Sbjct: 211 NIPVH 215
>UniRef50_Q12GF8 Cluster: Histone deacetylase superfamily; n=6;
Burkholderiales|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 353
Score = 81.0 bits (191), Expect = 4e-14
Identities = 45/132 (34%), Positives = 65/132 (49%), Gaps = 2/132 (1%)
Frame = +1
Query: 493 CPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCG-GWHHAHNNRAEGFCYVNDIVI 669
CP P+ + V A +V AA + D A C HHA + A GFCYVN+
Sbjct: 128 CPIGPHTWHSVLRSAHSAVAAADAVCQ-TGDAAYALCRPSGHHACRDSASGFCYVNNSAC 186
Query: 670 AIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-GTGSIEDIGC 846
A +L + + +D+D HHG+G Q ++ + V T+S H G+YP +G + G
Sbjct: 187 AAHRLLQHYGRVAVLDVDAHHGDGTQHIFYDSADVLTVSMHADPAGYYPFYSGYAHERGA 246
Query: 847 GDGEGYSCNFPL 882
G G G + N PL
Sbjct: 247 GAGAGCNLNLPL 258
>UniRef50_UPI0000D56143 Cluster: PREDICTED: similar to CG6170-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6170-PA, isoform A - Tribolium castaneum
Length = 824
Score = 80.6 bits (190), Expect = 5e-14
Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 5/96 (5%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA N G+CY N++ IA E + +G K ++ VD DVHHG G Q ++ V S
Sbjct: 184 HHAMENEYNGYCYFNNVAIAAESVLREGHSKRVMIVDFDVHHGQGTQRMFYERNDVLYFS 243
Query: 787 FHKFEPG-FYPG--TGSIEDIGCGDGEGYSCNFPLN 885
H++E G F+P + IG GDG G++ N PLN
Sbjct: 244 IHRYEHGTFWPNLLESNFNYIGRGDGLGFNVNVPLN 279
Score = 79.4 bits (187), Expect = 1e-13
Identities = 62/241 (25%), Positives = 114/241 (47%), Gaps = 11/241 (4%)
Frame = +1
Query: 196 LHFRFIM-NNARVAYLWDEKLVKEC-----IRLPAVFGRARLVHNLIEAYGLISKLKVIR 357
LH R+I ++ V Y++D+++++ + P R + +++ +GL+ +++
Sbjct: 458 LHERYICASDLPVNYIYDDQMLQHTPQSGDLERPERPERLTSIMKVLQEFGLLGRMQRTP 517
Query: 358 SSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIA 537
P + + + H+ YL + + + D N + + V + LV +
Sbjct: 518 IVPRDFTEYSP-HARGYLGTVNEAMEQSKDVYVNEHTHDSVV----LAVSGLLSLVDGVM 572
Query: 538 GGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILY 711
G+ A G+A I HHA +++A G+C+VN+I +A L K++ +L
Sbjct: 573 SGTSQA------GVAVIR----PPGHHAEHDKAMGYCFVNNIAVAANYLLDKYEVERVLI 622
Query: 712 VDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGTG--SIEDIGCGDGEGYSCNFPL 882
VD D+HHGNG Q+ ++ V +S HK E G F+P + G G G G++ N P
Sbjct: 623 VDFDIHHGNGTQNMFYENDRVMYVSIHKDEHGKFFPANSPRNYTFDGYGRGRGFNVNIPF 682
Query: 883 N 885
N
Sbjct: 683 N 683
>UniRef50_Q6AJC0 Cluster: Putative uncharacterized protein; n=1;
Desulfotalea psychrophila|Rep: Putative uncharacterized
protein - Desulfotalea psychrophila
Length = 324
Score = 80.6 bits (190), Expect = 5e-14
Identities = 56/206 (27%), Positives = 92/206 (44%), Gaps = 3/206 (1%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYIS 456
P V R ++ +E L+ LK + S A L + H + +L ++ +I
Sbjct: 26 PEVPARLEVILKCLEESPLLPHLKFVASRLARRASLLLAHEEDWLFRFEEAVLFGKSHID 85
Query: 457 NAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA-DIAINWCGGWHHAHNNR 633
+ ++ IGY + +++ + AG + L G A I HHA +
Sbjct: 86 HLDNQ---IGY------HTYQVAALAAGAGLKGIDLLEAGDARQIFCVIRPPGHHAEKGK 136
Query: 634 AEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG 807
GFC+ N+++IA + K+ + + +D D HHGNG+Q +S H+
Sbjct: 137 PFGFCFYNNVLIAARYWQEKYGRRRVAVIDFDAHHGNGIQAGLERDPKSLYISIHEHPSF 196
Query: 808 FYPGTGSIEDIGCGDGEGYSCNFPLN 885
YPGTG E+IG G G+G N PL+
Sbjct: 197 SYPGTGFAEEIGTGLGKGTILNLPLS 222
>UniRef50_Q7Z8L6 Cluster: Putative histone deacetylase; n=2;
Pleosporales|Rep: Putative histone deacetylase -
Cochliobolus carbonum (Bipolaris zeicola)
Length = 847
Score = 80.6 bits (190), Expect = 5e-14
Identities = 47/131 (35%), Positives = 71/131 (54%), Gaps = 9/131 (6%)
Frame = +1
Query: 514 FELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK 687
+E AGG++ A K + G IAI G HHA +++ GFC N++ IA +
Sbjct: 227 YECAKLAAGGAIEACKAVVQGAVRNAIAIIRPPG-HHAESDQPSGFCIFNNVPIATRVCQ 285
Query: 688 GKF----KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPG--TGSIEDIGC 846
+ + +L +D DVHHGNG+Q A++ +V +S H F+ G FYP G+++ G
Sbjct: 286 NAYPETCRKVLILDWDVHHGNGIQHAFYDDPNVLYISLHVFKDGTFYPNLPDGNLDYCGE 345
Query: 847 GDGEGYSCNFP 879
G GEG + N P
Sbjct: 346 GRGEGKNVNIP 356
>UniRef50_Q09C86 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Cystobacterineae|Rep: Histone
deacetylase/AcuC/AphA family protein - Stigmatella
aurantiaca DW4/3-1
Length = 587
Score = 80.2 bits (189), Expect = 7e-14
Identities = 48/128 (37%), Positives = 68/128 (53%), Gaps = 2/128 (1%)
Frame = +1
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEK 681
P+ ++ AG +V A + + G A A HHA RA GFC N++ IA E
Sbjct: 332 PDSYDAALLAAGAAVGAVEEVMAGRARNAFALVRPPGHHAEPGRAMGFCLFNNVAIAAEA 391
Query: 682 LKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGE 858
+ + +L +D DVHHGNG Q A+ R V S H++ +YPGTG+ ++G G GE
Sbjct: 392 GRRLGAERVLVLDWDVHHGNGTQAAFEGRRDVLYQSVHQYP--YYPGTGAPREVGQGAGE 449
Query: 859 GYSCNFPL 882
G+S N L
Sbjct: 450 GFSVNCAL 457
>UniRef50_Q0W553 Cluster: Putative acetoin utilization protein; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
acetoin utilization protein - Uncultured methanogenic
archaeon RC-I
Length = 331
Score = 80.2 bits (189), Expect = 7e-14
Identities = 50/157 (31%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Frame = +1
Query: 421 KQITDIDD-DYISNAQDENFG-IGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI 594
+Q+T + D DY+ + + G + D + AG ++ A + + G ++A
Sbjct: 54 RQLTRVHDLDYVRHIETSGTGMLDPDTEMTAGSLDAARLAAGAALDAVEEVRKG-RELAF 112
Query: 595 NWCGG-WHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRS 771
HHA RA GFC N+ I + ++ +L VD DVHHGNG Q ++ T
Sbjct: 113 GLVRPPGHHALPGRAMGFCIFNNAAIGAARALDHYRKVLVVDWDVHHGNGTQQIFYRTPD 172
Query: 772 VYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
V S H+ P F P TG + G G+GEG++ N PL
Sbjct: 173 VLYFSVHQ-SPHF-PYTGDAAETGEGEGEGFNVNVPL 207
>UniRef50_A4JTS4 Cluster: Histone deacetylase superfamily; n=3;
Bacteria|Rep: Histone deacetylase superfamily -
Burkholderia vietnamiensis (strain G4 / LMG 22486)
(Burkholderiacepacia (strain R1808))
Length = 376
Score = 79.8 bits (188), Expect = 9e-14
Identities = 57/194 (29%), Positives = 93/194 (47%), Gaps = 4/194 (2%)
Frame = +1
Query: 313 LIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYD 492
LI G+ L IR A+ EDL FH+ Y++ ++ +++ G
Sbjct: 50 LISVSGMNDHLVNIRPELATREDLLRFHTPEYVDKIRTLSE----------GRGGEAGEH 99
Query: 493 CPPVPNMFELVSTIAGGSVTAAKCLTMGIA--DIAINWCGGWHHAHNNRAEGFCYVNDIV 666
P P +E+ GG ++ + + G ++N G HHA ++ GFC + V
Sbjct: 100 TPFGPGGYEIACLSTGGCISLLESVYRGDVRNGYSLNRPPG-HHAVADQGRGFCIFGNGV 158
Query: 667 IAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDI 840
+AI +L+ K + VD DVHHGN QDA++ SV T+S H+ + + +G++ +
Sbjct: 159 VAIRRLQAMTGVKRVAVVDWDVHHGNSAQDAFYQDPSVLTISVHQ-DRNYPTDSGALSER 217
Query: 841 GCGDGEGYSCNFPL 882
G G G G + N PL
Sbjct: 218 GIGAGWGTNINIPL 231
>UniRef50_A6LM84 Cluster: Histone deacetylase superfamily; n=1;
Thermosipho melanesiensis BI429|Rep: Histone deacetylase
superfamily - Thermosipho melanesiensis BI429
Length = 315
Score = 79.4 bits (187), Expect = 1e-13
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 6/186 (3%)
Frame = +1
Query: 346 KVIRSSPASYEDLNVFHS---DLYLEHLKQITD-IDDDYISNAQDENFGIGYDCPPVPNM 513
K + PA +N H+ Y+EH+K+I+ +++Y+ ++ + P P
Sbjct: 41 KTFETIPAKEYPINYIHNIHPKWYVEHVKKISSSTNNEYLPEVFLKDRILDSGTPVTPVT 100
Query: 514 FELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK 693
++ S+T A L I G HHA + A G+C+ N+ I + L+
Sbjct: 101 YKAALNAYYASITGAN-LDEKYVYILTRPPG--HHASKDFAGGYCFFNNAAIIAKYLQSI 157
Query: 694 F-KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG-TGSIEDIGCGDGEGYS 867
+ K I +D+D HHGNG Q+ ++ ++ +S H F+P +G E+ G GDG+G +
Sbjct: 158 YQKRICILDIDFHHGNGTQEIFYYDPNIVYISIHGTPEKFFPWISGFREETGSGDGKGTN 217
Query: 868 CNFPLN 885
NFPL+
Sbjct: 218 FNFPLD 223
>UniRef50_Q17MD0 Cluster: Histone deacetylase; n=1; Aedes aegypti|Rep:
Histone deacetylase - Aedes aegypti (Yellowfever
mosquito)
Length = 1059
Score = 79.4 bits (187), Expect = 1e-13
Identities = 59/230 (25%), Positives = 111/230 (48%), Gaps = 10/230 (4%)
Frame = +1
Query: 226 RVAYLWDEKLVKECI---RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFH 396
RV +++DE L++ P R ++ E Y L++++K ++ A+ +L + H
Sbjct: 462 RVCFVYDESLLEHRNVHEDHPEQPDRVAKIYTRHEEYKLLARMKRLKPRHATTTELCMVH 521
Query: 397 SDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMG 576
S ++ +++ + ++ + D+ + + P FE + AG + + G
Sbjct: 522 SRQHVNVIRRTVEREE--MKQVADQFNSVYFH----PKTFECATLAAGSVLQVVDEVLNG 575
Query: 577 IA--DIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGV 744
+ + I G HHA ++ GFC N++ IA + K +L VD DVHHGNG
Sbjct: 576 QSRSGVCIVRPPG-HHAESDMPHGFCIFNNVAIAAQYAIRDHGLKRVLIVDWDVHHGNGT 634
Query: 745 QDAYWTTRSVYTLSFHKFEPG-FYPGT--GSIEDIGCGDGEGYSCNFPLN 885
Q + + V +S H+++ G F+P + + + +G G GEG++ N P N
Sbjct: 635 QHIFESDPRVLYISVHRYDNGTFFPKSTDANFDVVGSGSGEGFNVNIPWN 684
Score = 76.2 bits (179), Expect = 1e-12
Identities = 70/231 (30%), Positives = 103/231 (44%), Gaps = 13/231 (5%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWDE EC P F R V GL+ + K+I A+ E++ H+ +E
Sbjct: 47 LWDEGY-PEC---PERFTR---VLERCRELGLVDRCKMIEPRMATEEEILTKHTPEQVEI 99
Query: 418 LKQITDIDD----DYISNAQDENF--GIGYDCPPVP--NMFELVSTIAGGSVTAAKCLTM 573
L+ +D + +S+ D F YDC + + ELV + GG V
Sbjct: 100 LRGTKGSEDLERLEELSSHYDAVFVHPSSYDCSLLACGSTIELVDAVVGGRVQN------ 153
Query: 574 GIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQ 747
G+A I HHA G+C+ N++ IA + + K IL VD D+HHG G Q
Sbjct: 154 GMAIIR----PPGHHAMKAEYNGYCFFNNVAIAAQHALDRLGLKKILVVDWDIHHGQGTQ 209
Query: 748 DAYWTTRSVYTLSFHKFEPG-FYPG--TGSIEDIGCGDGEGYSCNFPLNXL 891
++ V S H++E G F+P + +G G G GY+ N PLN +
Sbjct: 210 RMFYDDPRVLYFSIHRYECGKFWPNLRESDFDYVGEGAGLGYNFNVPLNRI 260
>UniRef50_A5DRS6 Cluster: Histone deacetylase HDA1; n=7;
Saccharomycetales|Rep: Histone deacetylase HDA1 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 906
Score = 79.4 bits (187), Expect = 1e-13
Identities = 49/181 (27%), Positives = 89/181 (49%), Gaps = 10/181 (5%)
Frame = +1
Query: 367 ASYEDLNVFHSDLYLEHLKQITDIDDDYI--SNAQDENFGIGYDCPPVPNMFELVSTIAG 540
A+ E++ HS+ +LEH++ + D + A ++ + D + G
Sbjct: 270 ATIEEILEVHSEKHLEHIQSTETMTKDELLRETATGDSIYVNNDS------YFSAKLSCG 323
Query: 541 GSVTAAKCLTMG-IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF----KNI 705
G++ A K + G + + HHA + GFC +++ +A + + + + I
Sbjct: 324 GTIEACKAVIEGRVKNSLAAVRPPGHHAEPDDPGGFCLFSNVAVAAKNILKSYPESVRRI 383
Query: 706 LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGT--GSIEDIGCGDGEGYSCNF 876
+ +D D+HHGNG Q +++ V +S H++E G FYPGT G + +G G G+GY+ N
Sbjct: 384 VILDWDIHHGNGTQKSFYDDPRVLYISLHRYENGKFYPGTKYGGADQVGEGAGKGYNINI 443
Query: 877 P 879
P
Sbjct: 444 P 444
>UniRef50_Q64AZ9 Cluster: Deacetylase; n=1; uncultured archaeon
GZfos28B8|Rep: Deacetylase - uncultured archaeon
GZfos28B8
Length = 361
Score = 79.4 bits (187), Expect = 1e-13
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 2/124 (1%)
Frame = +1
Query: 517 ELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF 696
E I G + A + G + A++ GG HHA + EGFC ND+ + L ++
Sbjct: 106 EAARLIIGQAKRAVDLVESGEFEKAVSIGGGLHHAKPSFGEGFCLYNDVAYTAKYLMQEY 165
Query: 697 --KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSC 870
K IL +D D H GNG + ++ V + H+ YPGTG IG G G+GY+
Sbjct: 166 DLKRILILDTDAHAGNGTSEYFYQDPRVMFIDLHQDPRTIYPGTGFANQIGEGAGKGYTV 225
Query: 871 NFPL 882
N P+
Sbjct: 226 NVPM 229
>UniRef50_Q2QWU2 Cluster: Histone deacetylase family protein,
expressed; n=4; Magnoliophyta|Rep: Histone deacetylase
family protein, expressed - Oryza sativa subsp. japonica
(Rice)
Length = 443
Score = 79.0 bits (186), Expect = 2e-13
Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA GFC +I +A + + K ++ +D DVHHGNG DA++ ++ LS
Sbjct: 221 HHAVPEGPMGFCVFGNIAVAARYAQNQHGLKRVMIIDFDVHHGNGTCDAFYEDPDIFFLS 280
Query: 787 FHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
H+ G YPGTG I +G G+GEG + N PL
Sbjct: 281 THQL--GSYPGTGKIHQVGQGNGEGTTLNLPL 310
>UniRef50_A1C5E8 Cluster: Histone deacetylase hda1; n=8;
Eurotiomycetidae|Rep: Histone deacetylase hda1 -
Aspergillus clavatus
Length = 805
Score = 79.0 bits (186), Expect = 2e-13
Identities = 61/206 (29%), Positives = 107/206 (51%), Gaps = 10/206 (4%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISK-LKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
RA LV + + L+++ LK I + A+ E++++ H+ + ++ D+ DD + +
Sbjct: 171 RAGLVDDPESSRPLVARPLKRIHARNATEEEVSLVHTPDHFAFVESTKDMSDDELIALEH 230
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSV-TAAKCLTMGIAD-IAINWCGGWHHAHNNRAEG 642
I ++ + L+ST GG++ T T + + IA+ G HHA +++ G
Sbjct: 231 TRDSIYFN--KLTFASALLST--GGAIETCLAVATRKVKNAIAVIRPPG-HHAEHDKTMG 285
Query: 643 FCYVNDIVIAI----EKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG- 807
FC N++ +A ++L + IL VD DVHHGNG+Q A++ +V +S H ++ G
Sbjct: 286 FCLFNNVSVAARVCQKQLGESCRKILIVDWDVHHGNGIQKAFYDDPNVLYISLHVYQDGK 345
Query: 808 FYPG--TGSIEDIGCGDGEGYSCNFP 879
+YPG G + G G G G + N P
Sbjct: 346 YYPGGDEGDWDHCGAGAGLGRNVNIP 371
>UniRef50_A3DNS7 Cluster: Histone deacetylase superfamily; n=1;
Staphylothermus marinus F1|Rep: Histone deacetylase
superfamily - Staphylothermus marinus (strain ATCC 43588
/ DSM 3639 / F1)
Length = 352
Score = 79.0 bits (186), Expect = 2e-13
Identities = 36/87 (41%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +1
Query: 619 AHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHK 795
A N +GFC N+ + K + FK + +D+DVHHGNG Q+ ++ V + H+
Sbjct: 135 AFNAPTQGFCIFNNAAATVLGFKDRGFKRVAILDIDVHHGNGTQEIFYKNNDVLHIDIHR 194
Query: 796 FEPGFYPGTGSIEDIGCGDGEGYSCNF 876
FYP TG EDIG G G GYS NF
Sbjct: 195 NPHDFYPFTGFPEDIGMGRGRGYSVNF 221
>UniRef50_Q941D6 Cluster: Histone deacetylase 14; n=3;
Spermatophyta|Rep: Histone deacetylase 14 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 423
Score = 79.0 bits (186), Expect = 2e-13
Identities = 40/92 (43%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA GFC ++ IA + K I +D DVHHGNG DA+ ++ LS
Sbjct: 201 HHAVPKGPMGFCVFGNVAIAARHAQRTHGLKRIFIIDFDVHHGNGTNDAFTEDPDIFFLS 260
Query: 787 FHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
H + G YPGTG I DIG G GEG + N PL
Sbjct: 261 TH--QDGSYPGTGKISDIGKGKGEGTTLNLPL 290
>UniRef50_P53973 Cluster: Histone deacetylase HDA1; n=7;
Saccharomycetales|Rep: Histone deacetylase HDA1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 706
Score = 78.6 bits (185), Expect = 2e-13
Identities = 42/121 (34%), Positives = 67/121 (55%), Gaps = 9/121 (7%)
Frame = +1
Query: 538 GGSVTAAKCLTMGIA--DIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF----K 699
GG++ A K + G +A+ G HHA A GFC +++ +A + + + +
Sbjct: 179 GGAIEACKAVVEGRVKNSLAVVRPPG-HHAEPQAAGGFCLFSNVAVAAKNILKNYPESVR 237
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGT--GSIEDIGCGDGEGYSC 870
I+ +D D+HHGNG Q +++ V +S H+FE G +YPGT G + G G GEG++C
Sbjct: 238 RIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNC 297
Query: 871 N 873
N
Sbjct: 298 N 298
>UniRef50_Q8LRK8 Cluster: Histone deacetylase 18; n=1; Arabidopsis
thaliana|Rep: Histone deacetylase 18 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 682
Score = 78.6 bits (185), Expect = 2e-13
Identities = 61/206 (29%), Positives = 90/206 (43%), Gaps = 10/206 (4%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R++ ++ G+ + V+ S A + L + H+ ++ +K I+ D N
Sbjct: 85 RIRVIWEKLQLAGVTQRCVVLGGSKAEDKHLKLVHTKKHVNLVKSISTKKKDSRRNKIAS 144
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGF 645
Y E AG V A+ + G D AI G HHA ++ A GF
Sbjct: 145 QLDSIY---LNGGSSEAAYLAAGSVVKVAEKVAEGELDCGFAIVRPPG-HHAESDEAMGF 200
Query: 646 CYVNDIVIAIEKLKGK-----FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG- 807
C N++ +A L + K IL VD D+HHGNG Q +W V S H+ + G
Sbjct: 201 CLFNNVAVAASFLLNERPDLDVKKILIVDWDIHHGNGTQKMFWKDSRVLIFSVHRHDHGS 260
Query: 808 FYP--GTGSIEDIGCGDGEGYSCNFP 879
FYP G +G G GEG++ N P
Sbjct: 261 FYPFGDDGDFNMVGEGPGEGFNINVP 286
>UniRef50_Q7XAX9 Cluster: HDA1; n=3; Magnoliophyta|Rep: HDA1 - Zea
mays (Maize)
Length = 701
Score = 78.2 bits (184), Expect = 3e-13
Identities = 59/205 (28%), Positives = 90/205 (43%), Gaps = 9/205 (4%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R + + A G+ S+ +++ A + + HS +++ +K+I+ D N
Sbjct: 40 RLRSIWRKLNAAGVASRCVALKAKEAEDKYIASVHSKRHIKLMKEISSTIYDASRNKIAR 99
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFC 648
F Y E AG + A+ + G AI HHA ++ A GFC
Sbjct: 100 KFNSIY---LNKGSSESAVLAAGSVIEVAEKVAAGELSSAIALVRPPGHHAEHDEAMGFC 156
Query: 649 YVNDIVIAIEKLKGK-----FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-F 810
N++ +A L + K IL VD DVHHGNG Q ++ V S H+F+ G F
Sbjct: 157 LFNNVAVAANYLLNERPDLGIKKILIVDWDVHHGNGTQKMFYDDPRVLFFSVHRFDYGSF 216
Query: 811 YPGTGSIEDIGCGD--GEGYSCNFP 879
YP G G+ G+GY+ N P
Sbjct: 217 YPSEGDASHCFIGEEAGKGYNINVP 241
>UniRef50_Q20296 Cluster: Histone deacetylase 6; n=4;
Caenorhabditis|Rep: Histone deacetylase 6 -
Caenorhabditis elegans
Length = 955
Score = 78.2 bits (184), Expect = 3e-13
Identities = 49/178 (27%), Positives = 83/178 (46%), Gaps = 5/178 (2%)
Frame = +1
Query: 367 ASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGS 546
A+ E++ + H+ LEHL+ + D+ + ++ F Y + S
Sbjct: 478 ATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQS 537
Query: 547 VTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDL 720
V G + + HHA +++ GFC N++ +A + + + K K +L +D
Sbjct: 538 VDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDW 597
Query: 721 DVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
DVHHGNG Q+ ++ +V +S H+ + G FYP D+G G GEG S N P +
Sbjct: 598 DVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFS 655
Score = 67.7 bits (158), Expect = 4e-10
Identities = 57/195 (29%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Frame = +1
Query: 334 ISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNM 513
++K K++ L + +DL + H K + D + + + I C ++
Sbjct: 48 LTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVK---DLMESEKKTQEDINSQCEKYDSV 104
Query: 514 F--ELVSTIAGGSVTAAKCLTMGI-ADIAINWCG----GWHHAHNNRAEGFCYVNDIVIA 672
F E +A V + LT I A+ A N HHA + GFC N++ A
Sbjct: 105 FMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQA 164
Query: 673 IEK-LKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDI 840
E+ + IL VDLDVHHG+G Q ++ + V S H+ E G F+P + I
Sbjct: 165 AEEAFFSGAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHI 224
Query: 841 GCGDGEGYSCNFPLN 885
G G G GY+ N LN
Sbjct: 225 GSGKGLGYNANLALN 239
>UniRef50_UPI00015BB127 Cluster: histone deacetylase superfamily;
n=1; Ignicoccus hospitalis KIN4/I|Rep: histone
deacetylase superfamily - Ignicoccus hospitalis KIN4/I
Length = 345
Score = 77.8 bits (183), Expect = 3e-13
Identities = 55/200 (27%), Positives = 90/200 (45%), Gaps = 3/200 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + +L++ L + ++V P +L + H Y+E++K++ + Y+
Sbjct: 26 RVKAILDLMKRTKLPNYVEVRSPVPIDERELELVHDRDYVEYVKRVIEAGGGYLDP---- 81
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMG---IADIAINWCGGWHHAHNNRAEG 642
D P +E AG AA+ G +A A+ G HHA + G
Sbjct: 82 ------DTYASPTSWEPALYAAGTVAYAAQRAVEGDHWLAFAAVRPPG--HHARRSEGRG 133
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
FC N++ +A E L+ + + VD+DVH G+G ++ T V +S H+ YP
Sbjct: 134 FCIFNNVALAAEVLRRRGMRVAVVDIDVHWGDGTAYIFYNTDEVLYVSTHQDPRTLYPFE 193
Query: 823 GSIEDIGCGDGEGYSCNFPL 882
G G G GEGY+ N PL
Sbjct: 194 GFPSQKGSGKGEGYTVNVPL 213
>UniRef50_UPI0000D561E8 Cluster: PREDICTED: similar to CG1770-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG1770-PA, isoform A - Tribolium castaneum
Length = 883
Score = 77.8 bits (183), Expect = 3e-13
Identities = 37/90 (41%), Positives = 52/90 (57%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA +A GFC+ N + IA L+ + + IL D VHHGNG QD ++ V +S
Sbjct: 606 HHAEPQQAMGFCFFNSVAIAARVLQREHRVHKILIFDWGVHHGNGTQDIFYDDPRVLVIS 665
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+ + G F+PGTGS + G G G G++ N
Sbjct: 666 MHRHDDGNFFPGTGSPGECGAGAGVGFNVN 695
>UniRef50_A7HL59 Cluster: Histone deacetylase superfamily; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Histone
deacetylase superfamily - Fervidobacterium nodosum
Rt17-B1
Length = 325
Score = 77.8 bits (183), Expect = 3e-13
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 7/174 (4%)
Frame = +1
Query: 382 LNVFHSDLYLEHLKQ-ITDIDDDYISNA--QDENFGIGYDCPPVPNMFELVSTIAGGSVT 552
L + H + Y+E++K+ +++ +YI D+ F G P E G T
Sbjct: 63 LYLAHEEDYIEYIKRKSSEVTQEYIPEVFFVDKIFDTG-----TPINKETYKAAFGAVET 117
Query: 553 AAKCLTMGIADIAINWC---GGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLD 723
L +++ I + HHA G+CY N++ IA + L+ K + +DLD
Sbjct: 118 VLSALEYSLSNKVIVYALTRPPGHHAMKKYGGGYCYFNNVAIAAKYLEEKGMRVAILDLD 177
Query: 724 VHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG-TGSIEDIGCGDGEGYSCNFPL 882
HHGNG QD ++ +V +S H FYP +G +IG G+ EG + N PL
Sbjct: 178 FHHGNGTQDIFYDDPNVLYVSIHGDPRQFYPWYSGYENEIGIGNAEGTNLNIPL 231
>UniRef50_Q57955 Cluster: Uncharacterized protein MJ0535; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ0535 - Methanococcus jannaschii
Length = 343
Score = 77.4 bits (182), Expect = 5e-13
Identities = 34/82 (41%), Positives = 45/82 (54%)
Frame = +1
Query: 634 AEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFY 813
+ GFC N+I A K K ++ +D DVHHGNG Q+ +W V + FH + G Y
Sbjct: 136 SNGFCIFNNIAGAARLAKNYMKKVIIIDFDVHHGNGTQEIFWNDNRVIHIDFH--QRGIY 193
Query: 814 PGTGSIEDIGCGDGEGYSCNFP 879
PGTG I DIG + +G N P
Sbjct: 194 PGTGDILDIGGEEAKGTKINLP 215
>UniRef50_P56523 Cluster: Histone deacetylase clr3; n=1;
Schizosaccharomyces pombe|Rep: Histone deacetylase clr3
- Schizosaccharomyces pombe (Fission yeast)
Length = 687
Score = 77.0 bits (181), Expect = 6e-13
Identities = 38/96 (39%), Positives = 56/96 (58%), Gaps = 7/96 (7%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIA----IEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYT 780
HHA ++ GFC N++ + +++ K K +L VD D+HHGNG Q A++ +V
Sbjct: 194 HHAEPHKPGGFCLFNNVSVTARSMLQRFPDKIKRVLIVDWDIHHGNGTQMAFYDDPNVLY 253
Query: 781 LSFHKFEPG-FYPGT--GSIEDIGCGDGEGYSCNFP 879
+S H++E G FYPGT G E+ G G G G + N P
Sbjct: 254 VSLHRYENGRFYPGTNYGCAENCGEGPGLGRTVNIP 289
>UniRef50_Q2IF50 Cluster: Histone deacetylase superfamily; n=1;
Anaeromyxobacter dehalogenans 2CP-C|Rep: Histone
deacetylase superfamily - Anaeromyxobacter dehalogenans
(strain 2CP-C)
Length = 324
Score = 76.6 bits (180), Expect = 8e-13
Identities = 44/116 (37%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
Frame = +1
Query: 535 AGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNI 705
AG ++ AA+ + G A A HHA +RA G+C +N++ IA ++ G + +
Sbjct: 106 AGAAIEAAERVARGEARAAFALVRPPGHHAWADRAGGYCLLNNVAIAARAVQAAGLARRV 165
Query: 706 LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCN 873
L VD DVHH +G Q +W +VY LS H + YP TG+ E+ G G GEG + N
Sbjct: 166 LVVDWDVHHCDGTQSIFWEDSAVYVLSVHLWP--HYPHTGAPEERGAGAGEGTTRN 219
>UniRef50_Q0G2C9 Cluster: Putative acetylpolyamine aminohydrolase;
n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
acetylpolyamine aminohydrolase - Fulvimarina pelagi
HTCC2506
Length = 347
Score = 76.6 bits (180), Expect = 8e-13
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 2/132 (1%)
Frame = +1
Query: 493 CPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVI 669
C FE + A + TAA + +G A C HHA+ +RA GFC+ N+ I
Sbjct: 125 CAMGERTFEAIYESAMTAATAAD-IVLGGQPAAYALCRPPGHHAYPDRANGFCFFNNAAI 183
Query: 670 AIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG-TGSIEDIGC 846
A ++L+ K+ + +D D HHG+G Q ++ V+ S H +YP G ++ G
Sbjct: 184 AAQRLRSKYGKVAIIDFDTHHGDGTQAIFYDRGDVFVGSVHTETSEYYPHFFGYADETGR 243
Query: 847 GDGEGYSCNFPL 882
GEG + N PL
Sbjct: 244 EGGEGCNLNIPL 255
>UniRef50_Q6C4P0 Cluster: Similar to sp|P53973 Saccharomyces
cerevisiae YNL021w HDA1 histone deacetylase A; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P53973
Saccharomyces cerevisiae YNL021w HDA1 histone
deacetylase A - Yarrowia lipolytica (Candida lipolytica)
Length = 748
Score = 76.6 bits (180), Expect = 8e-13
Identities = 40/96 (41%), Positives = 54/96 (56%), Gaps = 7/96 (7%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF----KNILYVDLDVHHGNGVQDAYWTTRSVYT 780
HHA GFC +++ +A + L ++ K IL +D DVHHGNG Q A+ V
Sbjct: 238 HHAEPGNPAGFCMFSNVAVAAKVLLKRYPERVKRILILDWDVHHGNGTQRAFLDDPRVLY 297
Query: 781 LSFHKFEPG-FYPG--TGSIEDIGCGDGEGYSCNFP 879
+S H++E G FYPG G+ +G G GEGYS N P
Sbjct: 298 ISLHQYENGKFYPGGTFGAHTSVGTGAGEGYSVNIP 333
>UniRef50_A4S240 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 399
Score = 75.8 bits (178), Expect = 1e-12
Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA A GFC V A +L+G K +L D DVHHGNG D + SV +S
Sbjct: 180 HHAVPRGAMGFCLVGTAAAAARHAQLRGH-KKVLIFDYDVHHGNGTNDIFRDDDSVLFIS 238
Query: 787 FHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
H E G YPGTG I D+G GDG G + N PL
Sbjct: 239 TH--EDGSYPGTGKITDMGEGDGLGATINIPL 268
>UniRef50_Q1DTF8 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 724
Score = 75.8 bits (178), Expect = 1e-12
Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 12/208 (5%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISK-LKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
+A LV + + L+S+ L I + A++E++++ H + + + D+ +D + +
Sbjct: 156 KAGLVDDPDASRPLVSQPLLRIPARDATHEEISLIHDSEHYDFVLSTKDMSEDELIALES 215
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGF 645
I ++ F GG++ K + G AI HHA +A GF
Sbjct: 216 TRDSIYFNTLT----FTSAILACGGAIETCKAVVSGKVKNAIAVIRPPGHHAEQCQAMGF 271
Query: 646 CYVNDIVIAI----EKLKGKFKNILYVDLDVHH---GNGVQDAYWTTRSVYTLSFHKFEP 804
C N++ +A + K K + I+ VD DVHH GNGVQ+A++ +V +S H ++
Sbjct: 272 CLFNNVSVAARVCQKTFKDKCRKIMIVDWDVHHDLLGNGVQNAFYDDPNVLYISLHVYKD 331
Query: 805 G-FYPG--TGSIEDIGCGDGEGYSCNFP 879
G FYPG G+ + G G+G G + N P
Sbjct: 332 GAFYPGGEQGNWDHCGEGNGLGKNVNIP 359
>UniRef50_Q8RAS9 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=18;
cellular organisms|Rep: Deacetylases, including yeast
histone deacetylase and acetoin utilization protein -
Thermoanaerobacter tengcongensis
Length = 435
Score = 75.4 bits (177), Expect = 2e-12
Identities = 45/136 (33%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Frame = +1
Query: 490 DCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHN--NRAEGFCYVND 660
D V L+S AGG++ A + + D A HHA GFC +N
Sbjct: 71 DVKSVVTQSHLIS--AGGAIKALQAVMEKEVDKAFALVRPPGHHAQRVVYGDRGFCIINV 128
Query: 661 IVIAIEKLKGKFKN--ILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIE 834
+ +E+++ ++ N + VD D HHG+G QD YW + +S H+ YPGTG IE
Sbjct: 129 EAVMLERIRQEYGNLRVAIVDTDCHHGDGTQDIYWNDKDTLFISLHQDGRTLYPGTGFIE 188
Query: 835 DIGCGDGEGYSCNFPL 882
+ G GY+ N PL
Sbjct: 189 EFGGPAAYGYNINIPL 204
>UniRef50_UPI0000F2E91A Cluster: PREDICTED: similar to histone
deacetylase 6,; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to histone deacetylase 6, -
Monodelphis domestica
Length = 1143
Score = 74.9 bits (176), Expect = 2e-12
Identities = 54/195 (27%), Positives = 93/195 (47%), Gaps = 9/195 (4%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPV- 504
GL + V+ + A+ ++L HS+ Y+E ++ + + + G Y+ +
Sbjct: 593 GLTPRCFVLPARSATNQELLACHSEEYIERIRATSGLKPRDLHRE-----GTSYNSIYIS 647
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAI- 675
P+ F AG + + + +AI G HHA + A GFC+ N + +A
Sbjct: 648 PHSFCCAQLAAGAACRLVEAILAREVQNGLAIVRPPG-HHAERDAACGFCFFNSVAVAAR 706
Query: 676 --EKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDI 840
+++ G+ IL VD D+HHGNG Q + SV +S H+++ G F+P G+ +
Sbjct: 707 HAQEVAGRALRILIVDWDIHHGNGTQHIFEEDPSVLYVSLHRYDHGAFFPMAEDGASSHV 766
Query: 841 GCGDGEGYSCNFPLN 885
G G GEG++ N N
Sbjct: 767 GRGQGEGFNVNVAWN 781
Score = 71.7 bits (168), Expect = 2e-11
Identities = 65/225 (28%), Positives = 100/225 (44%), Gaps = 10/225 (4%)
Frame = +1
Query: 241 WDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHL 420
WDE + RL AV + +L + L+ + +I + PA+ E+L + HS Y++ +
Sbjct: 170 WDESFPERPERLQAV--QEQLARDC-----LLERCLLIEAQPATPEELQLVHSQEYVDLM 222
Query: 421 K---QITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA--D 585
Q+T+ + +S+ D + PN F G + L G
Sbjct: 223 ASTPQMTESERRALSDTYDSVY-------LHPNSFPCALLATGALLRLVDALMTGEIRNG 275
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYW 759
+A+ G HHA G+C N+I IA + + IL VD DVHHG G Q +
Sbjct: 276 LAVVRPPG-HHAQRESMNGYCMFNNIAIAARYAQERHHVARILIVDWDVHHGQGTQFIFE 334
Query: 760 TTRSVYTLSFHKFEPG-FYPGTGSIE--DIGCGDGEGYSCNFPLN 885
SV S H++E G F+P + + G G G+GY+ N P N
Sbjct: 335 QDPSVLCFSVHRYELGRFWPHLEASDWRATGHGKGQGYTVNVPWN 379
>UniRef50_Q63YT0 Cluster: Histone deacetylase family protein; n=12;
Burkholderia|Rep: Histone deacetylase family protein -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 370
Score = 74.9 bits (176), Expect = 2e-12
Identities = 56/199 (28%), Positives = 86/199 (43%), Gaps = 2/199 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L++A G+ +L + + A+ E L H YL L + + + + D+
Sbjct: 40 RLAYTKQLLDAVGMTERLTRVAFARATDEQLLRVHRPEYLRQLAEACAVAGEQVVRLGDD 99
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
G ++ L + A +V A + A I G HHA + A G+CY
Sbjct: 100 AAGSA----STEDVARLAAGAACAAVDAVMTGPLRQAYALIRPSG--HHAGADFAMGYCY 153
Query: 652 VNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTG 825
N++ IA + + + VD DVHHGNG Q A++ SV +S H+ F G
Sbjct: 154 YNNVAIAARHAQAAHGVERVAIVDWDVHHGNGTQQAFYDDPSVLFVSLHE-AANFPVDGG 212
Query: 826 SIEDIGCGDGEGYSCNFPL 882
+ G G G GY+ N PL
Sbjct: 213 EARETGGGAGAGYNANVPL 231
>UniRef50_Q4PCR1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 727
Score = 74.9 bits (176), Expect = 2e-12
Identities = 36/96 (37%), Positives = 55/96 (57%), Gaps = 7/96 (7%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIA---IEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTL 783
HHA ++ GFC+ N++ +A + + K +L +D DVHHGNG Q A+ +V +
Sbjct: 216 HHAEPQKSMGFCFFNNVAVATRVVLRRHAHIKKVLILDWDVHHGNGTQRAFEYDDNVLYI 275
Query: 784 SFHKFEP--GFYPGT--GSIEDIGCGDGEGYSCNFP 879
S H+++ FYPG+ G+ + G G GEG S N P
Sbjct: 276 SLHRYDEDGSFYPGSTYGNFDSAGTGPGEGRSVNIP 311
>UniRef50_Q9HSP7 Cluster: Acetoin utilization protein; n=5;
Halobacteriaceae|Rep: Acetoin utilization protein -
Halobacterium salinarium (Halobacterium halobium)
Length = 338
Score = 74.9 bits (176), Expect = 2e-12
Identities = 37/91 (40%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + A GFC+VN+ +A + + D DVHHGNG QD ++ V+ S
Sbjct: 121 HHAITDDAMGFCFVNNAAVAAQHALDAHGLDRVAIFDWDVHHGNGTQDIFYDRGDVFYTS 180
Query: 787 FHKFEPGFYPGTGSIEDIGCGDGEGYSCNFP 879
H E G YPGTGS+ G DG G + N P
Sbjct: 181 IH--EDGLYPGTGSVAQTGDCDGAGTTLNLP 209
>UniRef50_Q7ZYF0 Cluster: Hdac6-prov protein; n=2; Xenopus|Rep:
Hdac6-prov protein - Xenopus laevis (African clawed frog)
Length = 1286
Score = 74.5 bits (175), Expect = 3e-12
Identities = 58/235 (24%), Positives = 107/235 (45%), Gaps = 15/235 (6%)
Frame = +1
Query: 226 RVAYLWDEKLVK-----ECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
R A ++DE++++ +C P R + + GL+ + + S A+ ++L +
Sbjct: 481 RTALVYDEQMMEHRNMWDCYH-PESPQRINQIFKRHKDLGLLERCSRLPSRLATQKELQM 539
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y++ ++ + + DE I + + AG + + +
Sbjct: 540 CHSLSYIQKIEASAHMKPRDLHRLGDEYNSIYINS----KSYHSARLAAGSTFNVVEAVV 595
Query: 571 MGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKN---ILYVDLDVH 729
G A I HHA A GFC+ N + +A ++L+ + ++ ++ +D DVH
Sbjct: 596 TGKAQNGIGIVRPPGHHAEPGEACGFCFFNTVALAARYAQRLQSQSEDPLRVMILDWDVH 655
Query: 730 HGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGT--GSIEDIGCGDGEGYSCNFPLN 885
HGNG Q + SV +S H+++ G F+P + S + +G G G GY+ N P N
Sbjct: 656 HGNGTQHIFQEDASVLYMSLHRYDEGLFFPNSEDASHDKVGIGKGAGYNVNIPWN 710
Score = 69.3 bits (162), Expect = 1e-10
Identities = 63/224 (28%), Positives = 97/224 (43%), Gaps = 8/224 (3%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWDE EC P GR V + + YGL + + + AS E++ + HS Y+
Sbjct: 95 LWDENF-PEC---P---GRIWAVRDKMAEYGLAERCVAVPAREASEEEILLIHSPQYVAL 147
Query: 418 LKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIA--DI 588
++ + D + D YD + P F S G + + G +
Sbjct: 148 MRSTQKMTMDELRALSDR-----YDSVYLHPTSFTCASLAVGSVLQLVDRVQHGEIRNGL 202
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWT 762
A+ G HHAH ++ G+C N + IA +L K +L VD DVHHG G Q + +
Sbjct: 203 AVVRPPG-HHAHTDQMNGYCMFNQLAIAARYAQLTYGAKRVLIVDWDVHHGQGTQFIFES 261
Query: 763 TRSVYTLSFHKFE-PGFYP--GTGSIEDIGCGDGEGYSCNFPLN 885
SV S H+++ GF+P + +G GE ++ N N
Sbjct: 262 DPSVLYFSVHRYDNGGFWPHLKESASSAVGKERGERFNVNVAWN 305
>UniRef50_Q30PJ4 Cluster: Histone deacetylase superfamily; n=1;
Thiomicrospira denitrificans ATCC 33889|Rep: Histone
deacetylase superfamily - Thiomicrospira denitrificans
(strain ATCC 33889 / DSM 1351)
Length = 577
Score = 74.5 bits (175), Expect = 3e-12
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
HHA GFCY N +A L F + +D+D HHGNG QD ++ R V T+S H
Sbjct: 392 HHAERRTLGGFCYFNSAAVAAHHLSS-FGKVAVLDVDFHHGNGTQDIFYERRDVLTISIH 450
Query: 793 KFEPGF-YPGTGSIEDIGCG--DGEGYSCNFPL 882
+P F YP +D CG +GEG++ N+PL
Sbjct: 451 G-DPKFAYPHFAGFKD-ECGEKEGEGFNINYPL 481
>UniRef50_A4YNH4 Cluster: Acetylpolyamine aminohydrolase; n=15;
Proteobacteria|Rep: Acetylpolyamine aminohydrolase -
Bradyrhizobium sp. (strain ORS278)
Length = 374
Score = 74.5 bits (175), Expect = 3e-12
Identities = 34/91 (37%), Positives = 51/91 (56%), Gaps = 1/91 (1%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
HHA+ + A GFC++N+ IA L+ + + + +D+DVHHGNG Q ++ V T+S H
Sbjct: 190 HHAYRDIASGFCFMNNSAIAAAHLRQRHERVAILDVDVHHGNGTQGIFYERPDVLTISIH 249
Query: 793 KFEPGFYPGT-GSIEDIGCGDGEGYSCNFPL 882
+YP G + G G G G + N PL
Sbjct: 250 ADPTHYYPFVWGYAHERGAGAGLGANLNIPL 280
>UniRef50_Q1MQQ3 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Lawsonia intracellularis PHE/MN1-00|Rep: Deacetylases,
including yeast histone deacetylase and acetoin
utilization protein - Lawsonia intracellularis (strain
PHE/MN1-00)
Length = 432
Score = 74.1 bits (174), Expect = 4e-12
Identities = 46/124 (37%), Positives = 66/124 (53%), Gaps = 8/124 (6%)
Frame = +1
Query: 535 AGGSVTAAKCLTMGIAD--IAINWCGGWHHA----HNNRAEGFCYVNDIVIAIEKLKGKF 696
AGG++ A+K + G + AI G HHA + NR GFC +N + +E ++ +
Sbjct: 85 AGGAIHASKLVLTGEVERAFAIIRPPG-HHAMRVTYGNR--GFCNINIEAVMVEHIRQTY 141
Query: 697 KN--ILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSC 870
K I VD D HHG+G QD YW +V +S H+ YPGTG +E++G G +
Sbjct: 142 KKQKIAIVDTDCHHGDGTQDIYWNDPNVLFISLHQDGRTTYPGTGFLEEVGGPAALGKTV 201
Query: 871 NFPL 882
N PL
Sbjct: 202 NIPL 205
>UniRef50_A6G5J4 Cluster: Histone deacetylase superfamily protein;
n=1; Plesiocystis pacifica SIR-1|Rep: Histone
deacetylase superfamily protein - Plesiocystis pacifica
SIR-1
Length = 274
Score = 73.7 bits (173), Expect = 6e-12
Identities = 41/118 (34%), Positives = 63/118 (53%), Gaps = 2/118 (1%)
Frame = +1
Query: 535 AGGSVTAAKCLTMGIA-DIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILY 711
AG ++ AA+ + G A++ G HHA + G+CY N+ IA +L+ ++
Sbjct: 58 AGCALDAARAVRAGAPLAYALSRPPG-HHAEEDMFGGYCYFNNSAIAARELRQGGARVVV 116
Query: 712 VDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-GTGSIEDIGCGDGEGYSCNFPL 882
+D+D HHGNG Q + TT V T+S H ++P TG + G G+G GY+ N L
Sbjct: 117 LDIDFHHGNGTQSLFQTTAEVLTVSLHGDPRAYFPFYTGYPRETGEGEGSGYNLNLVL 174
>UniRef50_UPI0000F1E289 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 650
Score = 72.5 bits (170), Expect = 1e-11
Identities = 61/200 (30%), Positives = 95/200 (47%), Gaps = 6/200 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + ++ GL S+ K+++ A+ E+L HS E L + Y S
Sbjct: 283 RVTSIWSRLQECGLRSQCKLLKGRSATVEELLSVHS----EELVCFFTGPEPYRSQM--- 335
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTA-AKCLTMGIA--DIAINWCGGWHHAHNNRAEG 642
+ G + P ++ A GSVT A C+ G A+ G HHA ++
Sbjct: 336 DIGTMWKNPRNSEALKM----AVGSVTELALCVARGDLRNGFAVVTPPG-HHASRSQTLD 390
Query: 643 FCYVNDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FY 813
N + IA ++L+ K K IL VD DVHHG+G + ++T SV +S H+++ G F+
Sbjct: 391 SIVFNSVAIAAKQLQEQLKVKKILIVDWDVHHGSGTESIFYTDPSVLYISLHRYDDGAFF 450
Query: 814 PGTGSIEDIGCGDGEGYSCN 873
GTG +GC G GY+ N
Sbjct: 451 NGTGDPSRVGCDVGRGYNVN 470
>UniRef50_Q803K0 Cluster: Zgc:55652; n=4; Danio rerio|Rep: Zgc:55652
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 676
Score = 72.5 bits (170), Expect = 1e-11
Identities = 51/205 (24%), Positives = 92/205 (44%), Gaps = 7/205 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + + +GL + K + A+ +++ + HS+ YLE +KQ ++ + + +
Sbjct: 32 RLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKK 91
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA--DIAINWCGGWHHAHNNRAEGF 645
+ + N++ AG ++ + +A+ G HH+ + A GF
Sbjct: 92 YNDVYFH----QNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPG-HHSQRSAANGF 146
Query: 646 CYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE-PGFYP 816
C N++ A K + IL VD DVHHG G+Q + SV S+H++E F+P
Sbjct: 147 CVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWP 206
Query: 817 G--TGSIEDIGCGDGEGYSCNFPLN 885
+G G G G++ N P N
Sbjct: 207 NLPESDYSSVGKGKGSGFNINLPWN 231
>UniRef50_A1ID65 Cluster: Histone deacetylase family protein; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Histone
deacetylase family protein - Candidatus Desulfococcus
oleovorans Hxd3
Length = 345
Score = 72.5 bits (170), Expect = 1e-11
Identities = 35/93 (37%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA +RA GFC +N++ IA +++ + IL VD DVHHGNG+ D ++ V+ +S
Sbjct: 125 HHALPDRATGFCLLNNLAIAARYARMRYNLERILIVDWDVHHGNGIHDIFYREPGVFYVS 184
Query: 787 FHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPLN 885
H +P +G D G G G++ N PL+
Sbjct: 185 SHDLM--LFPYSGEAGDTGEAGGRGFTLNMPLS 215
>UniRef50_Q23M98 Cluster: Histone deacetylase family protein; n=1;
Tetrahymena thermophila SB210|Rep: Histone deacetylase
family protein - Tetrahymena thermophila SB210
Length = 2774
Score = 72.5 bits (170), Expect = 1e-11
Identities = 33/94 (35%), Positives = 53/94 (56%), Gaps = 3/94 (3%)
Frame = +1
Query: 607 GWHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYT 780
G H + GFC+ N++ IA + L+ K +L D D+HHG+G Q + +V
Sbjct: 2258 GHHSGESKVCTGFCFFNNVAIAAKYLQKNHGVKKVLIFDWDIHHGDGTQHIFQDDPNVLF 2317
Query: 781 LSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCNFP 879
+S H+ + G FYP +GS+ + G G+G+G+ N P
Sbjct: 2318 VSMHRHDDGSFYPQSGSVTNNGSGEGKGFKINIP 2351
>UniRef50_Q969S8 Cluster: Histone deacetylase 10; n=20;
Euteleostomi|Rep: Histone deacetylase 10 - Homo sapiens
(Human)
Length = 669
Score = 72.5 bits (170), Expect = 1e-11
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>UniRef50_Q4FNF7 Cluster: Histone deacetylase family protein; n=5;
Bacteria|Rep: Histone deacetylase family protein -
Pelagibacter ubique
Length = 309
Score = 72.1 bits (169), Expect = 2e-11
Identities = 32/79 (40%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA N+A GFC N++ + L K K K I +D DVHHGNG QD ++ V +S
Sbjct: 124 HHAEKNKAMGFCIYNNVAVGANYLINKYKLKKIAIIDFDVHHGNGTQDIFYDNEKVLYIS 183
Query: 787 FHKFEPGFYPGTGSIEDIG 843
H++ +YPG+G+ ++ G
Sbjct: 184 THQYP--YYPGSGTNDEKG 200
>UniRef50_Q987Q0 Cluster: Acetylpolyamine aminohydrolase; n=1;
Mesorhizobium loti|Rep: Acetylpolyamine aminohydrolase -
Rhizobium loti (Mesorhizobium loti)
Length = 346
Score = 71.3 bits (167), Expect = 3e-11
Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 3/153 (1%)
Frame = +1
Query: 433 DIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI-ADIAINWCGG 609
D+ D I +AQ + I V +E V ++TAA + G A A+ G
Sbjct: 100 DVAPDSI-DAQLGQYSIDASTGFVEGTWEAVKASHDSALTAADLIIEGEQACFALCRPPG 158
Query: 610 WHHAHNNRAEGFCYVNDIVIAIEKL-KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + G+C+VN+ +A ++L G + +D+D HHGNG Q+ ++ V +S
Sbjct: 159 -HHAGTDFNGGYCFVNNAAVAAQRLLDGGASRVTILDIDYHHGNGTQEIFYARGDVQVVS 217
Query: 787 FHKFEPGFYP-GTGSIEDIGCGDGEGYSCNFPL 882
H YP G ++ G G GEG++ N PL
Sbjct: 218 LHADPRNDYPFFAGYADERGSGSGEGFNINIPL 250
>UniRef50_Q0LE47 Cluster: Histone deacetylase superfamily; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Histone
deacetylase superfamily - Herpetosiphon aurantiacus ATCC
23779
Length = 345
Score = 71.3 bits (167), Expect = 3e-11
Identities = 57/211 (27%), Positives = 95/211 (45%), Gaps = 5/211 (2%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEA-YGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYI 453
P R R +H ++ A Y L L + A+ ++ H +L L+++ D
Sbjct: 20 PENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVHVPSHLPTLQRMAQFGDW-- 77
Query: 454 SNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMG--IADIAINWCGGWHHAHN 627
A E + + P+ E+ AGG++ A + G A+ G HHA
Sbjct: 78 --ADAETYIL-------PDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRPPG-HHATA 127
Query: 628 NRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE 801
++A GFC N+ IA + ++ K + +D DVHHGNG QD ++ V +S H +
Sbjct: 128 DQAMGFCLFNNAAIAAAFAQREYGLKRVAILDWDVHHGNGTQDIFYQNPDVLYISTHGWP 187
Query: 802 PGFYPGTGSIEDIGCGDGEGYSCNFPLNXLS 894
+P +G +++G G G + N PL L+
Sbjct: 188 --LWPNSGHWKEMGANAGLGTTLNLPLRPLT 216
>UniRef50_Q94EJ2 Cluster: Histone deacetylase 8; n=14;
Magnoliophyta|Rep: Histone deacetylase 8 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 377
Score = 71.3 bits (167), Expect = 3e-11
Identities = 48/179 (26%), Positives = 86/179 (48%), Gaps = 6/179 (3%)
Frame = +1
Query: 364 PASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGG 543
PA +L +FH+ Y+E L + ++ E I P +E AG
Sbjct: 69 PAIVSELLMFHTSEYIEKLVE---------ADKSGERCEIAAGTFMSPGSWEAALLAAGT 119
Query: 544 SVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYV 714
+++A + + IA HH+ +A+G+C++N+ +A++ G + +
Sbjct: 120 TLSAMQHILDCHGKIAYALVRPPGHHSQPTQADGYCFLNNAALAVKLALNSGSCSRVAVI 179
Query: 715 DLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGF---YPGTGSIEDIGCGDGEGYSCNFPL 882
D+DVH+GNG + ++T+ V T+S H + +P GSI+++G G GY+ N PL
Sbjct: 180 DIDVHYGNGTAEGFYTSDKVLTVSLHMNHGSWGSSHPQKGSIDELGEDVGLGYNLNVPL 238
>UniRef50_Q8D858 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=31; Gammaproteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Vibrio vulnificus
Length = 312
Score = 70.9 bits (166), Expect = 4e-11
Identities = 37/92 (40%), Positives = 51/92 (55%), Gaps = 2/92 (2%)
Frame = +1
Query: 523 VSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKF 696
+++ AG +TA K L G+A I+ GG+HHAH + GFC ND+V+A K G
Sbjct: 100 LTSTAGTVLTAEKALQHGVA---IHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSV 156
Query: 697 KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
+L +D DVHHG+G + TLSFH
Sbjct: 157 DKVLIIDSDVHHGDGTATLCQRRDDIVTLSFH 188
>UniRef50_A5UY48 Cluster: Histone deacetylase superfamily; n=4;
Chloroflexaceae|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 344
Score = 70.9 bits (166), Expect = 4e-11
Identities = 57/201 (28%), Positives = 85/201 (42%), Gaps = 4/201 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + A GL S L + + PA+ L H++ +E ++ +A
Sbjct: 25 RLHAITAALNASGLRSVLLEVPARPATEAQLRAVHTEQMIEVVRW----------SATRP 74
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGF 645
I +D ++ AG ++ + G A A+ G HHA + GF
Sbjct: 75 RSWIDHDTYTTSASWDAALMAAGTTLAVVDAVVSGSAQNGFALVRPPG-HHATRAESMGF 133
Query: 646 CYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
C N++ IA + VD DVHHGNG QD ++ V+ S H P YPG
Sbjct: 134 CLFNNVAIAARHAIDHLGVTRVAIVDFDVHHGNGTQDIFYDDDRVFFCSTHA-SP-LYPG 191
Query: 820 TGSIEDIGCGDGEGYSCNFPL 882
TG+ +IG G G G + N PL
Sbjct: 192 TGAEREIGSGRGRGTTMNLPL 212
>UniRef50_Q9YG09 Cluster: Putative uncharacterized protein; n=1;
Aeropyrum pernix|Rep: Putative uncharacterized protein -
Aeropyrum pernix
Length = 366
Score = 70.9 bits (166), Expect = 4e-11
Identities = 49/168 (29%), Positives = 72/168 (42%), Gaps = 5/168 (2%)
Frame = +1
Query: 394 HSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTM 573
HS YL H+ + D++ D + +G P + + G SV +
Sbjct: 61 HSPAYLRHVLSTAESGLDWL----DPDTYVG------PGTLVALKRLGGASVEVYNIVRS 110
Query: 574 GIADIAINWCGGWHHAHNNRA-----EGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGN 738
G + + G H RA GFC VN + L + K ++ +D D+HHGN
Sbjct: 111 GGEALLLGRPPGHHAGIRGRALGAPTAGFCIVNTAALIARMLSEQGKTVI-LDFDLHHGN 169
Query: 739 GVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
G Q+ ++ VY + H+ YPGTG EDIG GD +G N L
Sbjct: 170 GTQEIFYDDPDVYHVDVHQDPTTIYPGTGFPEDIGEGDAKGTKINIIL 217
>UniRef50_Q3SA60 Cluster: Deacetylase; n=1; uncultured euryarchaeote
Alv-FOS4|Rep: Deacetylase - uncultured euryarchaeote
Alv-FOS4
Length = 347
Score = 70.9 bits (166), Expect = 4e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +1
Query: 364 PASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGG 543
PA+ ED+ H++ YLE L++++ ++ D + Y E S IA
Sbjct: 49 PANMEDILAVHTEPYLEFLERMSMRGPTFLG---DSTYLNKYSYLAALMAAE-ASIIASD 104
Query: 544 SVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDL 720
V + A + G HHA + G+C +N+ I ++ + + + +D
Sbjct: 105 YVVN---MDYDFAYALVRPPG--HHATEDMYGGYCLLNNAAITARHVQERGLRRVAIIDW 159
Query: 721 DVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
D H NG +++TR V +S H+ FYP G I IG G+G GY+ N PL
Sbjct: 160 DAHAANGTMKIFYSTRDVLLISLHRDPRDFYPHEGFIHQIGRGEGTGYTVNIPL 213
>UniRef50_Q985Y7 Cluster: Mlr7469 protein; n=13;
Alphaproteobacteria|Rep: Mlr7469 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 308
Score = 70.5 bits (165), Expect = 5e-11
Identities = 43/127 (33%), Positives = 58/127 (45%), Gaps = 3/127 (2%)
Frame = +1
Query: 481 IGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD-IAINWCGGWHHAHNNRAEGFCYVN 657
I D P ++ V G + A + G AD + + HHA A GFC+ N
Sbjct: 79 IDADTTASPKSWQAVIAAIGAANAAVDDVFAGRADNVFVAARPPGHHAEKTTAMGFCFFN 138
Query: 658 DIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
IA + K + + VD DVHHGNG QD +W SV S H+ YPGTG+
Sbjct: 139 TAAIAARYAQNKHGAERVAVVDWDVHHGNGTQDIFWDDPSVLYCSTHQMP--LYPGTGAK 196
Query: 832 EDIGCGD 852
+ G G+
Sbjct: 197 TETGAGN 203
>UniRef50_Q8F254 Cluster: Histone deacetylase family protein; n=4;
Leptospira|Rep: Histone deacetylase family protein -
Leptospira interrogans
Length = 302
Score = 68.5 bits (160), Expect = 2e-10
Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 3/191 (1%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENF 477
++V++L++ +S L + + A +DL++ H+ +L DD+ S E
Sbjct: 31 QMVYDLVKRDSKLSNLYIYKPDLAKTKDLSLVHTQEFL----------DDFFSLNITERT 80
Query: 478 GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVN 657
+ P + GG++ + + + GG+HH+ +RAEGFCY+N
Sbjct: 81 QYS-ELPLTKQIVHSFVLAVGGTILSMELAQK--YKFVYHIGGGFHHSMPDRAEGFCYLN 137
Query: 658 DIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
D IA + + ++ K IL++DLD+H GNG + V+T S H + YP
Sbjct: 138 DAAIASKLYQKEYPDKKILFIDLDLHQGNGNSFIFQNDPDVFTFSMH--QENLYPKKEKS 195
Query: 832 E-DIGCGDGEG 861
+ DI +G G
Sbjct: 196 DLDISLEEGIG 206
>UniRef50_Q31EP6 Cluster: Histone deacetylase family protein
precursor; n=1; Thiomicrospira crunogena XCL-2|Rep:
Histone deacetylase family protein precursor -
Thiomicrospira crunogena (strain XCL-2)
Length = 379
Score = 68.5 bits (160), Expect = 2e-10
Identities = 54/199 (27%), Positives = 93/199 (46%), Gaps = 7/199 (3%)
Frame = +1
Query: 304 VHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGI 483
++N +E G+ +L + + A+ E+L + H+ Y++ ++ ++D + Q + +
Sbjct: 64 INNEMEKQGIWPQLTPVATRLATNEELLLAHTQSYIDEIEILSDSGGGFYEPYQGDTYLN 123
Query: 484 GYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVN 657
+ F+ AG ++ + D A+ G HHA N+A GFC N
Sbjct: 124 A-------SSFDAAKMAAGSNINLNLAIYDRKIDHGFALLRPPG-HHALQNKAMGFCIFN 175
Query: 658 DIVIA---IEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGS 828
+IA ++K +G K I +D DVHHGNG QD S+ ++S H+ F+P TG
Sbjct: 176 SDIIAARALQKYRG-VKRIAIIDFDVHHGNGTQDLSDNDPSIMSISIHQHP--FWPMTGG 232
Query: 829 IEDIGCGDGEG--YSCNFP 879
G +G +C FP
Sbjct: 233 HTFTGKDKAKGTVVNCPFP 251
>UniRef50_A1I9M7 Cluster: Histone deacetylase superfamily; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Histone
deacetylase superfamily - Candidatus Desulfococcus
oleovorans Hxd3
Length = 578
Score = 68.5 bits (160), Expect = 2e-10
Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
HHA + GFCY N IA L + + +D+D HHGNG Q+ ++ ++TLS H
Sbjct: 393 HHAETSMFGGFCYFNSAAIAAHYLS-RHGRVAILDIDYHHGNGQQEIFYRRADIFTLSIH 451
Query: 793 KFEPGFYP-GTGSIEDIGCGDGEGYSCNFPL 882
YP +G E+ G G+G++ N PL
Sbjct: 452 GHPRFTYPFFSGFAEETGEAGGKGFNLNLPL 482
>UniRef50_Q8WZR5 Cluster: Related to histone deacetylase A; n=4;
Sordariomycetes|Rep: Related to histone deacetylase A -
Neurospora crassa
Length = 747
Score = 68.5 bits (160), Expect = 2e-10
Identities = 55/186 (29%), Positives = 89/186 (47%), Gaps = 17/186 (9%)
Frame = +1
Query: 367 ASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDEN--FGIGYDCPPVPNM-FELVSTIA 537
A+ E++ + H + EH + + D+ S + + G D V +M FE A
Sbjct: 142 ATKEEICIVH---HPEHFRWVEDLSRKPTSELRRLSTIMDQGRDSLYVGSMTFEAALISA 198
Query: 538 GGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEKLKGKF----KN 702
GG++ K + +G A HHA + GFC N++ IA + + ++ +
Sbjct: 199 GGAIETCKSVVVGNVKNAFAVIRPPGHHAEFDAPMGFCLFNNVPIAAKICQTEYPEICRK 258
Query: 703 ILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPG--------TGSIEDIGCGDG 855
IL +D DVHHGNG+Q+ ++ ++ +S H + G FYPG GSIE+ G G G
Sbjct: 259 ILILDWDVHHGNGIQNMFYDDPNILYISLHVYMNGSFYPGKPDNPMTPDGSIENCGAGPG 318
Query: 856 EGYSCN 873
G + N
Sbjct: 319 LGKNVN 324
>UniRef50_Q2S0V9 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Bacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Salinibacter
ruber (strain DSM 13855)
Length = 307
Score = 67.7 bits (158), Expect = 4e-10
Identities = 52/167 (31%), Positives = 76/167 (45%), Gaps = 4/167 (2%)
Frame = +1
Query: 304 VHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGI 483
+H + LI V+ A + DL H+ YL HL + + +S+ + G+
Sbjct: 27 LHQRLLDEDLIRPTDVVAPRQADWTDLRRVHTADYLTHLAEGS------LSDHAERRMGL 80
Query: 484 GYDCPPVPNMFELVSTIA-GGSVTAAKCLTMGIAD-IAINWCGGWHHAHNNRAEGFCYVN 657
P S +A G++ AA M + D +A N GG HHA EGFC +N
Sbjct: 81 -----PWSERLVYRSRLAVQGTINAA---LMALTDGVAANLAGGTHHAFPGHGEGFCVLN 132
Query: 658 DIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
D+ +AI L+ + +L VDLDVH GN + SV+T S H
Sbjct: 133 DVAVAIRVLQAACWAQRVLIVDLDVHQGNANAAVFADDASVFTFSMH 179
>UniRef50_A0C8R8 Cluster: Chromosome undetermined scaffold_159,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_159,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 366
Score = 67.7 bits (158), Expect = 4e-10
Identities = 44/106 (41%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Frame = +1
Query: 541 GSVTAAK-CLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKG--KFKNILY 711
GS+ AAK L G A IN GG+HHA NR GFC DI + + LK K I+
Sbjct: 167 GSIQAAKLALEKGWA---INLSGGYHHASLNRGGGFCIYPDITLVVNYLKRCCNLKKIVI 223
Query: 712 VDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIED-IGC 846
VDLD H GNG + + SVY + F + YPG E I C
Sbjct: 224 VDLDAHQGNGYERDFLNDSSVYIIDF--YNSYIYPGDHIAEQAISC 267
>UniRef50_Q1IJP8 Cluster: Histone deacetylase superfamily; n=1;
Acidobacteria bacterium Ellin345|Rep: Histone
deacetylase superfamily - Acidobacteria bacterium
(strain Ellin345)
Length = 357
Score = 67.3 bits (157), Expect = 5e-10
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 3/141 (2%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
G+ S + +PA+ D+ + HS Y++ L + T A++E + + P
Sbjct: 59 GVASTQDFLTPTPATEADVLLVHSHFYVDKLIEGT-------LTAREE---LALEIPYSH 108
Query: 508 NMFELVSTIAGGSVTAA-KCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL 684
+ GG++ AA + L+ G+A N GG+HHA+ + EGFC ++D+ +AI KL
Sbjct: 109 EAVQAFLWHTGGTILAAERALSDGVA---FNLGGGFHHAYPDHGEGFCMIHDVAVAIRKL 165
Query: 685 --KGKFKNILYVDLDVHHGNG 741
+G+ + ++ +D DVH GNG
Sbjct: 166 QKQGRIQRVMTLDCDVHQGNG 186
>UniRef50_A6SGS8 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 780
Score = 67.3 bits (157), Expect = 5e-10
Identities = 49/185 (26%), Positives = 89/185 (48%), Gaps = 16/185 (8%)
Frame = +1
Query: 367 ASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGG 543
A +++ + H+ + + ++ + + + + A ++ + G V P ++ AGG
Sbjct: 157 ARKDEICLAHTAFHYDWVESLLSMTSEELREA-NQRYDTGRKSLYVGPCTYDAALVAAGG 215
Query: 544 SVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKF----KNI 705
++ K + +G IAI G HHA N A GFC N++ IA + + + +
Sbjct: 216 AIETCKHVVVGNVKNAIAIIRPPG-HHAEENEALGFCVFNNVPIAAKVCMADYPEICRKV 274
Query: 706 LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPG--------TGSIEDIGCGDGE 858
L +D D+HHGNG Q+ ++ +V +S H ++ G FYPG G + +G G G
Sbjct: 275 LILDWDIHHGNGTQNMFYDDPNVLYISLHVYDNGQFYPGQPDDPSLPDGGNDKVGRGAGL 334
Query: 859 GYSCN 873
G + N
Sbjct: 335 GKNVN 339
>UniRef50_Q57ET7 Cluster: Histone deacetylase family protein; n=33;
Bacteria|Rep: Histone deacetylase family protein -
Brucella abortus
Length = 337
Score = 66.9 bits (156), Expect = 7e-10
Identities = 41/119 (34%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
Frame = +1
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIAD-IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
P + T G ++ A + G AD + + HHA +RA GFC N+I IA
Sbjct: 116 PKSMDAALTAIGAAMAAVDDVMSGAADNVFVASRPPGHHAERSRAMGFCVFNNIAIAARH 175
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGD 852
+ + I VD DVHHGNG QD + V S H+F YPG+G + G G+
Sbjct: 176 AQRHHGLERIAIVDGDVHHGNGTQDIFKDDPGVMFCSTHQFP--LYPGSGDKHETGVGN 232
>UniRef50_Q8TLY4 Cluster: Histone deacetylase; n=3; cellular
organisms|Rep: Histone deacetylase - Methanosarcina
acetivorans
Length = 546
Score = 66.9 bits (156), Expect = 7e-10
Identities = 36/96 (37%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Frame = +1
Query: 613 HHA----HNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSV 774
HHA H NR GFC +N+ I +E L+ K+ + I VD DVHHG+G Q+ ++ V
Sbjct: 206 HHAMAVSHGNR--GFCNINNEAILVEYLRKKYGIRRIAIVDTDVHHGDGTQEIFYNDPDV 263
Query: 775 YTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
+SFH+ +PG+G ++G G + N PL
Sbjct: 264 LFISFHQDGRTIFPGSGFTYELGGPKALGRTINIPL 299
>UniRef50_Q604Q2 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=29; Proteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Methylococcus
capsulatus
Length = 310
Score = 66.5 bits (155), Expect = 9e-10
Identities = 35/82 (42%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + A GFC N+I IA + I VD DVHHGNG Q A+ V +S
Sbjct: 124 HHAEPDAAMGFCLFNNIAIAAAHALANHGLQRIAIVDFDVHHGNGTQAAFRRNPQVLYVS 183
Query: 787 FHKFEPGFYPGTGSIEDIGCGD 852
H++ +YPGTGS E+ G G+
Sbjct: 184 THQYP--WYPGTGSAEETGVGN 203
>UniRef50_A3K7Q8 Cluster: Acetylpolyamine aminohydrolase; n=1;
Sagittula stellata E-37|Rep: Acetylpolyamine
aminohydrolase - Sagittula stellata E-37
Length = 326
Score = 66.5 bits (155), Expect = 9e-10
Identities = 59/201 (29%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Frame = +1
Query: 352 IRSSPASYEDLNVFHSDLYLEHLKQI-TDID-------DDYISNAQDEN-FG-------- 480
I + PA++EDL + HS+ +L LK T+ + D Y N FG
Sbjct: 34 IEADPAAHEDLRLVHSEAFLAFLKSAWTEWEAAFGPELDGYGFVWPTRNAFGRIPEAIEG 93
Query: 481 -IGYDCPP-----VPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEG 642
IG+ C P M+ AG ++ AA+ + G HHA + G
Sbjct: 94 KIGHFCFDGVSGLTPGMWMASVGAAGAALAAARSVLAGEGHAFAACRPPGHHASADLMGG 153
Query: 643 FCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-G 819
Y+N+ +A + + + VD+D HHGNG Q +W V T S H YP
Sbjct: 154 TSYLNNAALAAAWMANQGARVATVDIDAHHGNGTQSVFWARGDVLTTSLHIDPAHDYPYF 213
Query: 820 TGSIEDIGCGDGEGYSCNFPL 882
TG ++ G G G G + N PL
Sbjct: 214 TGYADERGEGAGAGLNLNAPL 234
>UniRef50_Q4RSK1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF15000, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 411
Score = 66.1 bits (154), Expect = 1e-09
Identities = 51/181 (28%), Positives = 85/181 (46%), Gaps = 6/181 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R ++ ++ GL + + A+ D+ + HS+ YLE +K+ Y++
Sbjct: 30 RLKVCAEALKRTGLADRCVSVPVREATDADILLAHSEEYLEAVKKTP-----YMTLGDLM 84
Query: 472 NFGIGY-DCPPVPNMFELVSTIAGGSVTAAKCLTMGIA--DIAINWCGGWHHAHNNRAEG 642
F + Y D PN++ AG ++ + G +A+ G HH+ + A G
Sbjct: 85 EFTLQYGDVYFHPNIYHCAKLAAGAALQLVDSVMTGAVRNGMALVRPPG-HHSMRSAANG 143
Query: 643 FCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE-PGFY 813
FC N++ IA K K+ + +L VD DVHHG GVQ + SV S+H++E F+
Sbjct: 144 FCVFNNVAIAARYAKQKYSLQRVLIVDWDVHHGQGVQYCFEDDPSVLYFSWHRYEHQKFW 203
Query: 814 P 816
P
Sbjct: 204 P 204
>UniRef50_Q5LQF5 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=3; Rhodobacteraceae|Rep: Histone
deacetylase/AcuC/AphA family protein - Silicibacter
pomeroyi
Length = 371
Score = 66.1 bits (154), Expect = 1e-09
Identities = 55/199 (27%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENF 477
R + NL++A GL L +R A+ E + + H +++HL + + D
Sbjct: 51 RRLQNLVQATGLWEHLSHLRPKRAADEVIRMVHPQSHIDHLASVCE------RGGGDA-- 102
Query: 478 GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYV 654
G P P E+ GG + A + G A+ A C HHA + A GFC +
Sbjct: 103 --GELTPAGPASLEIARLAVGGVIVAMDAVMTGAAENAYVLCRPPGHHALPDLAMGFCLL 160
Query: 655 NDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP-GTG 825
+ + I ++ + I VD DVHHGNG + + V T+S H + +P +G
Sbjct: 161 ANAALGIRHVQKTYGLTRIAVVDWDVHHGNGTEAVFLDDPGVLTISLH--QDNLFPLDSG 218
Query: 826 SIEDIGCGDGEGYSCNFPL 882
I G G+ + N PL
Sbjct: 219 GIGVKGAGNS---NINVPL 234
>UniRef50_A0DIS2 Cluster: Chromosome undetermined scaffold_52, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_52,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 645
Score = 66.1 bits (154), Expect = 1e-09
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +1
Query: 607 GWHHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYT 780
G H H N+ GFC N++ +A + + K+ I+ D DVHH +G + ++ +
Sbjct: 150 GHHSGHKNKPNGFCVYNNVAVAAKYARAKYNVNKIVIFDWDVHHCDGTESIFYEDPNTLV 209
Query: 781 LSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCNFPLN 885
+S H+++ G FYPG+G IG D E + N N
Sbjct: 210 ISIHRYDGGSFYPGSGDPVKIGRKDAEYKNINVGWN 245
>UniRef50_Q8ZU23 Cluster: Acetylpolyamine aminohydrolase, putative;
n=4; Pyrobaculum|Rep: Acetylpolyamine aminohydrolase,
putative - Pyrobaculum aerophilum
Length = 336
Score = 66.1 bits (154), Expect = 1e-09
Identities = 34/82 (41%), Positives = 46/82 (56%)
Frame = +1
Query: 637 EGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
+GFC N IA + + VD+DVHHGNG Q+ + +Y +S H+ YP
Sbjct: 129 QGFCIFNTAAIAALYVG---EGAAVVDIDVHHGNGTQEILYDKDLLY-ISTHQHPATLYP 184
Query: 817 GTGSIEDIGCGDGEGYSCNFPL 882
GTG E++G G GEGY+ N PL
Sbjct: 185 GTGYPEEVGEGRGEGYNINIPL 206
>UniRef50_Q48935 Cluster: Acetylpolyamine aminohydrolase; n=32;
Proteobacteria|Rep: Acetylpolyamine aminohydrolase -
Mycoplana ramosa (Mycoplana bullata)
Length = 341
Score = 66.1 bits (154), Expect = 1e-09
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSF 789
HHA + G+C++N+ +A ++L K K I +D+D HHGNG QD ++ V+ S
Sbjct: 158 HHAGIDMFGGYCFINNAAVAAQRLLDKGAKKIAILDVDFHHGNGTQDIFYERGDVFFASL 217
Query: 790 HKFEPGFYPG-TGSIEDIGCGDGEGYSCNFPL 882
H +P G E+ G G G G + N+P+
Sbjct: 218 HGDPAEAFPHFLGYAEETGKGAGAGTTANYPM 249
>UniRef50_Q5QWS4 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Idiomarina|Rep: Histone
deacetylase/AcuC/AphA family protein - Idiomarina
loihiensis
Length = 311
Score = 65.7 bits (153), Expect = 2e-09
Identities = 45/146 (30%), Positives = 69/146 (47%), Gaps = 3/146 (2%)
Frame = +1
Query: 364 PASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGG 543
P S+E + H YL L+Q N+ D++ P + T AGG
Sbjct: 52 PLSWEQVARTHCPGYLSQLRQ----------NSMDKSSWRRIGFPWSEQLLYRTLTSAGG 101
Query: 544 SV-TAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYV 714
++ T LT G+A I++ GG+HHAH + GFC +ND+ IA ++ + I+ +
Sbjct: 102 TLLTTELALTKGVA---IHFSGGYHHAHKDWGSGFCLLNDLAIACNEILVRHPKLKIVVL 158
Query: 715 DLDVHHGNGVQDAYWTTRSVYTLSFH 792
D DVH G+G + V+T S H
Sbjct: 159 DTDVHQGDGTATLFENDNRVFTCSIH 184
>UniRef50_A5UZV6 Cluster: Histone deacetylase superfamily; n=5;
Bacteria|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 346
Score = 65.7 bits (153), Expect = 2e-09
Identities = 34/93 (36%), Positives = 47/93 (50%), Gaps = 3/93 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + G+C++N+ IA E L +D+DVHHGNG Q ++ V +S
Sbjct: 158 HHAGRDLCGGYCFLNNAAIAAEYLIRNAAGATCAILDIDVHHGNGTQQIFYERNDVLFVS 217
Query: 787 FHKFEPGFYP-GTGSIEDIGCGDGEGYSCNFPL 882
H YP G ++ G G GEGY+ N PL
Sbjct: 218 IHASPDYQYPFFLGYADERGAGAGEGYNLNLPL 250
>UniRef50_Q00U49 Cluster: Histone deacetylase superfamily; n=3;
Ostreococcus|Rep: Histone deacetylase superfamily -
Ostreococcus tauri
Length = 749
Score = 65.7 bits (153), Expect = 2e-09
Identities = 37/91 (40%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Frame = +1
Query: 538 GGSVTAAKCLTMGI-ADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI-----EKLKGKFK 699
GG+V A+ + G A A GG HHA+ +R EGFC NDI AI ++L + +
Sbjct: 536 GGTVACAREVLAGFGARAAAQLAGGTHHAYRDRGEGFCVFNDIGTAIRVVQRDELLPRDR 595
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
IL +DLDVH GNG + + V T S H
Sbjct: 596 KILVIDLDVHQGNGTAKMFEHDQQVVTFSMH 626
>UniRef50_Q9A2B7 Cluster: Histone deacetylase family protein; n=9;
Alphaproteobacteria|Rep: Histone deacetylase family
protein - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 304
Score = 64.9 bits (151), Expect = 3e-09
Identities = 55/184 (29%), Positives = 81/184 (44%), Gaps = 3/184 (1%)
Frame = +1
Query: 313 LIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYD 492
L+EA + R P E L + HS+ Y+ + +++ + D + IG
Sbjct: 34 LLEAERVAGPDGFARPEPVDVETLCLAHSEDYVRGVIELS-LPPDIVRR-------IGM- 84
Query: 493 CPPVPNMFELVSTIAGGSVTAAK-CLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVI 669
P ++ GG++ AA+ L GIA N GG HHA + GFC ND+ +
Sbjct: 85 -PNTESVATRARAATGGTLLAARLALERGIA---CNTAGGSHHAAADAGAGFCVFNDVAV 140
Query: 670 AIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIG 843
A +L +G L VDLDVH G+G + SV+T S H + + S DI
Sbjct: 141 AARRLLAEGAIGKALVVDLDVHQGDGTARIFENDPSVFTFSMHAEKNFPHRKASSDLDIE 200
Query: 844 CGDG 855
DG
Sbjct: 201 LSDG 204
>UniRef50_A5UTM3 Cluster: Histone deacetylase superfamily; n=4;
Bacteria|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 298
Score = 64.9 bits (151), Expect = 3e-09
Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 2/124 (1%)
Frame = +1
Query: 496 PPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIA- 672
P P++ E G ++ A + G IA + GG HHA + EG+C ND VIA
Sbjct: 78 PWSPHLVERSRRSVGATIAACRTALSGDG-IAASLAGGTHHAFADHGEGYCVFNDSVIAA 136
Query: 673 -IEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCG 849
+ + +G+ + ++ +D DVH GNG+ ++++ S H + + S DI
Sbjct: 137 RVMQAEGRVRRVVIIDCDVHQGNGIAAILAGDETIFSFSIHGAKNYPFRKERSNLDIALE 196
Query: 850 DGEG 861
DG G
Sbjct: 197 DGTG 200
>UniRef50_UPI000065FABE Cluster: Histone deacetylase 6 (HD6).; n=1;
Takifugu rubripes|Rep: Histone deacetylase 6 (HD6). -
Takifugu rubripes
Length = 1154
Score = 64.5 bits (150), Expect = 3e-09
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 8/198 (4%)
Frame = +1
Query: 316 IEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDC 495
+E L+S++ ++ A+ E+L + HS Y++ +K + ++ + + D+ I
Sbjct: 77 LEQQDLLSRVTRVQPREAT-EELLLCHSQHYVDLMKSTQTMTEEELHSLSDKYDSIYLH- 134
Query: 496 PPVPNMFELVSTIAGGSVTAA--KCLTMGIAD-IAINWCGGWHHAHNNRAEGFCYVNDIV 666
P F V+ +A GSV + +T + + A+ G HHA + GF N++
Sbjct: 135 ---PESFS-VAVMAVGSVLQLVDQVMTSELRNGFAVVRPPG-HHAQKDLPNGFSIFNNVA 189
Query: 667 IAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGTGSIED 837
IA + + +L VD DVHHG G+Q + SV S H+FE G F+P +
Sbjct: 190 IAARYAQTRHSVSRVLIVDWDVHHGQGIQYLFQEDPSVLYFSVHRFEQGSFWPHLPESDS 249
Query: 838 --IGCGDGEGYSCNFPLN 885
+G EG + N P N
Sbjct: 250 HFVGSSGAEGSNINLPWN 267
Score = 56.4 bits (130), Expect = 9e-07
Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 7/94 (7%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAI---EKLKGKFK-NILYVDLDVHHGNGVQDAYWTTRSVYT 780
HHA + GFC+ N +A +KL ++L +D DVHHGNG Q + SV
Sbjct: 589 HHAERDFPCGFCFFNTAALAARHAQKLSQDAPLHVLILDWDVHHGNGTQHMFEDDDSVLY 648
Query: 781 LSFHKFEPG-FYPGT--GSIEDIGCGDGEGYSCN 873
+S H+++ G F+P + + + +G G GY+ N
Sbjct: 649 ISLHRYDNGAFFPSSEDAAPDRVGVAKGVGYNVN 682
>UniRef50_Q54X15 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1489
Score = 64.5 bits (150), Expect = 3e-09
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
Frame = +1
Query: 634 AEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG 807
++GFC +N + I + +LK I +D DVHHGNG ++ + Y LS H FE G
Sbjct: 1244 SQGFCLLNHVCIGAKYAQLKYNLDKIAIIDFDVHHGNGTEEILSNDQGFYFLSIHMFEEG 1303
Query: 808 FYPGTG 825
FYPG+G
Sbjct: 1304 FYPGSG 1309
>UniRef50_Q5K8L3 Cluster: Histone deacetylase 3, putative; n=2;
Filobasidiella neoformans|Rep: Histone deacetylase 3,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 555
Score = 64.5 bits (150), Expect = 3e-09
Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 36/178 (20%)
Frame = +1
Query: 460 AQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAE 639
A+ + + + +D P P + +S + + TA + L AD A+ W GG HHA A
Sbjct: 220 ARTDPYNLSHDNPVFPTLASYISHVTAATSTACRLLATDKADWAVCWDGGRHHAKRKEAG 279
Query: 640 GFCYVNDIVIA-------------------IEKLKGKFKNILYVDLDVHHGNGVQDAYWT 762
GFCYVND+V+ ++ + + ILY+D+D+H+ +GV A+ +
Sbjct: 280 GFCYVNDLVLGGLLLSREGRIPLPLKEGEDPKRQRTRAPRILYLDMDLHYSDGVSAAFHS 339
Query: 763 TR----------------SVYTLSFHKFEPGFYPGTGSIEDIGCGDGEG-YSCNFPLN 885
+V TLS H P F+P + + D E +S + PL+
Sbjct: 340 PTVYPYPLKEGITPPKPPNVLTLSVHHSSPIFFPPPTPLSLLPSPDTESPFSLSIPLS 397
Score = 33.1 bits (72), Expect = 9.8
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +1
Query: 226 RVAYLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLI 336
RV+YLW L + LP+ GR+ +VH+LI + L+
Sbjct: 58 RVSYLWSPALQRLSDDLPSNVGRSSMVHDLIRSLDLL 94
>UniRef50_Q981D8 Cluster: Deacetylase, putative; n=3;
Sulfolobus|Rep: Deacetylase, putative - Sulfolobus
solfataricus
Length = 327
Score = 64.5 bits (150), Expect = 3e-09
Identities = 45/185 (24%), Positives = 82/185 (44%)
Frame = +1
Query: 319 EAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCP 498
+A I++LKV P +D + HS+ Y++ +++ + +++ N ++ + Y
Sbjct: 28 KALSAINQLKVKFKKPIKVDDPQIIHSEDYVKLVEKHSKLEE----NLDEDTYTNRYT-- 81
Query: 499 PVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIE 678
+E GG++ A + + + G A GFC N++ I+
Sbjct: 82 -----YESALYAMGGALEAFETNGFALVRPPGHHAGVNGRAFGAPTLGFCIFNNVAYPIK 136
Query: 679 KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGE 858
K K K + +D DVH+GNG Q+ ++ + + H+ YPG G + IG D E
Sbjct: 137 KYK--LKRVAIIDFDVHYGNGTQEIFYDDPDILHIDVHQDPRTIYPGNGFPDMIGEKDAE 194
Query: 859 GYSCN 873
G N
Sbjct: 195 GTKIN 199
>UniRef50_A0KLZ2 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=3; Gammaproteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Aeromonas
hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB
9240)
Length = 319
Score = 63.7 bits (148), Expect = 6e-09
Identities = 47/148 (31%), Positives = 71/148 (47%), Gaps = 3/148 (2%)
Frame = +1
Query: 358 SSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIA 537
++PA+ E + H Y+E T +D D I +G+ P P + E
Sbjct: 65 AAPATPEQIKRVHDAAYVEAALAGT-LDADAIRQ-------LGF--PWSPLLMERTLRSV 114
Query: 538 GGSVTAAK-CLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNIL 708
G ++ A++ L G + GG+HHAH + GFC ND+VIA + +G+ + +L
Sbjct: 115 GATLAASRHALEQGCG---LQISGGYHHAHRDVGSGFCLFNDLVIAAQVCLDEGRCEQVL 171
Query: 709 YVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
VDLDVH G+G R + TLS H
Sbjct: 172 IVDLDVHQGDGSAALCQGRRDIITLSLH 199
>UniRef50_A0B6D0 Cluster: Histone deacetylase superfamily; n=1;
Methanosaeta thermophila PT|Rep: Histone deacetylase
superfamily - Methanosaeta thermophila (strain DSM 6194
/ PT) (Methanothrixthermophila (strain DSM 6194 / PT))
Length = 284
Score = 63.7 bits (148), Expect = 6e-09
Identities = 38/112 (33%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 523 VSTIAGGSVT-AAKCLTMGIADIAINWCG-GWHHAHNNRAEGFCYVNDIVIAIEKL-KGK 693
V+ ++ GSV AA+ + G A+ A + G HHA GFCY ND+ I I KL K
Sbjct: 77 VALLSAGSVLMAAELVVSGKAESAFAYTGTAGHHASRGSCWGFCYFNDVAITILKLRKMG 136
Query: 694 FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCG 849
K L +D+D H G+G +D + V+ ++FH + + D G G
Sbjct: 137 LKRFLIIDVDPHFGDGTRDFFGNDPDVFHINFHSGSQKEFDHERNNYDFGIG 188
>UniRef50_P28606 Cluster: Uncharacterized 34.1 kDa protein in glnA
3'region; n=15; Cyanobacteria|Rep: Uncharacterized 34.1
kDa protein in glnA 3'region - Synechococcus sp. (strain
PCC 7002) (Agmenellum quadruplicatum)
Length = 310
Score = 63.7 bits (148), Expect = 6e-09
Identities = 43/114 (37%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Frame = +1
Query: 529 TIAGGSV-TAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFK 699
T GG++ TA L G+A N GG HHA GFC +ND+ IA + +G +
Sbjct: 104 TAVGGTILTAQLALEHGLA---CNTAGGTHHAFPGYGSGFCILNDLAIATRTIQQRGLAQ 160
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEG 861
IL VDLDVH G+G + +V+T S H E F P D+ G EG
Sbjct: 161 RILIVDLDVHQGDGTAFIFQDDPTVFTFSMH-CEVNF-PSQKQRSDLDLGLPEG 212
>UniRef50_Q8EFZ9 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=10; Proteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Shewanella
oneidensis
Length = 304
Score = 63.3 bits (147), Expect = 8e-09
Identities = 34/90 (37%), Positives = 49/90 (54%), Gaps = 2/90 (2%)
Frame = +1
Query: 529 TIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKN 702
++AG S+TAA L GIA ++ GG+HHAH G+C ND++IA KL + +
Sbjct: 95 SLAGTSLTAALALQTGIA---LHLTGGYHHAHYEFGSGYCIFNDLIIAARKLIIEQQLHK 151
Query: 703 ILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
IL D DVH G+G + + + S H
Sbjct: 152 ILIFDCDVHQGDGTATLSQLHQGIISCSIH 181
>UniRef50_Q3IF01 Cluster: Putative histone deacetylase family
protein; n=3; Alteromonadales|Rep: Putative histone
deacetylase family protein - Pseudoalteromonas
haloplanktis (strain TAC 125)
Length = 306
Score = 63.3 bits (147), Expect = 8e-09
Identities = 36/108 (33%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIADIAI-NWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
P+ + + G + A + G D A + HHA+ + GFC N++ IA++
Sbjct: 88 PDSLKAIERAVGAGILAVDEILEGNLDAAFCSVRPPGHHANRTTSSGFCVFNNLAIAVKY 147
Query: 682 LKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
+ K K I VD DVHHGNG QD + ++V S F+ FYP T
Sbjct: 148 AQSKGVKRIAIVDFDVHHGNGTQDIFIDDKNVLFCSL--FQHPFYPNT 193
>UniRef50_Q12A19 Cluster: Histone deacetylase superfamily; n=4;
Proteobacteria|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 359
Score = 63.3 bits (147), Expect = 8e-09
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLK-GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSF 789
HHA + G+C++N+ +A + L+ G + +D+D HHGNG Q ++ V +S
Sbjct: 175 HHAGPDFMGGYCFLNNAAVAAQALRDGGAARVAVLDVDYHHGNGTQSIFYDRADVLFVSL 234
Query: 790 HKFEPGFYP-GTGSIEDIGCGDGEGYSCNFPL 882
H YP G ++ G G+G G++ N PL
Sbjct: 235 HGDPLTEYPFYLGHADETGAGEGAGFNLNLPL 266
>UniRef50_Q4TFH7 Cluster: Chromosome undetermined SCAF4471, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF4471,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1260
Score = 62.9 bits (146), Expect = 1e-08
Identities = 52/206 (25%), Positives = 91/206 (44%), Gaps = 8/206 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + ++ GL+S+ + A+ E+L + H+ +++ L+ + +D + + D+
Sbjct: 100 RVTFIMEELQHQGLLSQCTRVEPREATEEELLLCHTKHHVDLLRSTQTMTEDELHSLSDK 159
Query: 472 NFGIGYDCPPV-PNMFELVSTIAGGSVTAA-KCLTMGIAD-IAINWCGGWHHAHNNRAEG 642
YD + P F T G + + +T + + A+ G HHA + G
Sbjct: 160 -----YDSVYLHPESFTAGVTAVGSLLQLVDRVMTSELRNGFAVVRPPG-HHAQKDLPNG 213
Query: 643 FCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FY 813
FC N++ IA + + +L VD DVHHG G Q + SV S H++E G F+
Sbjct: 214 FCLFNNVAIAARYAQTRHSVSRVLIVDWDVHHGQGTQYLFQEDPSVLYFSVHRYEQGSFW 273
Query: 814 PGTGSIED--IGCGDGEGYSCNFPLN 885
P + +G G + N P N
Sbjct: 274 PHLPESDSHFVGTPRAAGRNINLPWN 299
Score = 57.2 bits (132), Expect = 5e-07
Identities = 37/128 (28%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Frame = +1
Query: 514 FELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFCYVNDIVIAIEKLKG 690
F+ AGG +A + + G A+ HHA + GFC+ N +A +
Sbjct: 649 FQSALLAAGGCFSAVEQILAGQVRNAVAVVRPPGHHAERDLPCGFCFFNTAALAARHAQK 708
Query: 691 KFKN----ILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYPGT--GSIEDIGCG 849
++ +L +D DVHHGNG Q + SV +S H+++ G F+P + + + +G
Sbjct: 709 LSRDAPLRVLILDWDVHHGNGTQHMFEDDDSVLYISLHRYDNGAFFPSSEDAAPDRVGVS 768
Query: 850 DGEGYSCN 873
G GY+ N
Sbjct: 769 KGAGYNVN 776
>UniRef50_A1U7D4 Cluster: Histone deacetylase superfamily; n=5;
Proteobacteria|Rep: Histone deacetylase superfamily -
Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 361
Score = 62.9 bits (146), Expect = 1e-08
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSF 789
HHAH + G+C+ N+ I + + + + + +D+D HHGNG Q ++ V T+S
Sbjct: 176 HHAHADLFGGYCFFNNAAIVAQAFRDQGYGKVAILDVDFHHGNGTQAIFYDRADVLTISL 235
Query: 790 HKFEPGFYPGTGSIED-IGCGDGEGYSCN 873
H +P ED +G G GEGY+ N
Sbjct: 236 HGDPDLVFPHFLGFEDELGEGTGEGYNLN 264
>UniRef50_Q22CW6 Cluster: Histone deacetylase family protein; n=1;
Tetrahymena thermophila SB210|Rep: Histone deacetylase
family protein - Tetrahymena thermophila SB210
Length = 359
Score = 62.9 bits (146), Expect = 1e-08
Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 8/192 (4%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRS-SPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDEN 474
+++ NL + GL S+L VI P + LN H D Y++ ++Q+ + + EN
Sbjct: 37 KIIENLKKT-GLWSQLDVINQVEPIQKDILNKVHRDSYVDLVEQM------WPEGCEKEN 89
Query: 475 F---GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGF 645
G Y+ + F L S S+ K + A + G H + + GF
Sbjct: 90 MVLNGCYYNKYTGQSAF-LSSGAVIQSIDLIKSKSWHTAFCCVR-PPGHHSGASQQCSGF 147
Query: 646 CYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP 816
C+ N++V+ + L+ K+ K I D DVHHG+G Q + + +S H+++ G FYP
Sbjct: 148 CFFNNVVVGAKYLREKYSVKKIAIFDFDVHHGDGTQALTYDDHELLFISIHQYDEGKFYP 207
Query: 817 -GTGSIEDIGCG 849
+G + +G G
Sbjct: 208 FQSGDLSKVGNG 219
>UniRef50_Q0M412 Cluster: Histone deacetylase superfamily; n=1;
Caulobacter sp. K31|Rep: Histone deacetylase superfamily
- Caulobacter sp. K31
Length = 336
Score = 62.5 bits (145), Expect = 1e-08
Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSF 789
HHA A GFC ++I +A + K + VD DVHHGNG Q A+ SV+ S
Sbjct: 154 HHAEPGVAMGFCVFSNIAVAARVAQASGLKRVAIVDFDVHHGNGTQAAFEHDASVFFASI 213
Query: 790 HKFEPGFYPGTGSIEDIGCGD 852
H + YPGTG + G G+
Sbjct: 214 H--QSPLYPGTGDPSETGVGN 232
>UniRef50_A1G0Y5 Cluster: Histone deacetylase superfamily precursor;
n=1; Stenotrophomonas maltophilia R551-3|Rep: Histone
deacetylase superfamily precursor - Stenotrophomonas
maltophilia R551-3
Length = 312
Score = 62.5 bits (145), Expect = 1e-08
Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Frame = +1
Query: 535 AGGSVTAAKCLTMG---IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGK--FK 699
AG V A + +G +A A+ G HHA ++ A GFC +N+I IA + + +
Sbjct: 94 AGAGVAAVDAVMLGEDPLAFCAVRPPG--HHATSSTAMGFCLLNNIAIAAAYARDRHGLE 151
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGD 852
I VD DVHHGNG QD + V S H + G +P +G D G G+
Sbjct: 152 RIAVVDFDVHHGNGTQDIFQHDARVSYYSTH--QAGLFPNSGLRRDRGAGN 200
>UniRef50_Q8U2L6 Cluster: Aminohydrolase; n=4; Thermococcaceae|Rep:
Aminohydrolase - Pyrococcus furiosus
Length = 335
Score = 62.5 bits (145), Expect = 1e-08
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +1
Query: 640 GFCYVNDIVIAIEKLKGK-FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
GFC N+ A+ LK + ++ +D D HHGNG Q+ +W V + H E YP
Sbjct: 136 GFCIFNNAASAVVTLKEEGVGKVVVIDFDAHHGNGTQEIFWNDPDVIHIDLH--ERDIYP 193
Query: 817 GTGSIEDIGCGDGEGYSCNFPL 882
G+G + ++G + G N P+
Sbjct: 194 GSGDVSEVGGSNAYGSKINLPM 215
>UniRef50_A6T202 Cluster: Histone deacetylase superfamily protein;
n=1; Janthinobacterium sp. Marseille|Rep: Histone
deacetylase superfamily protein - Janthinobacterium sp.
(strain Marseille) (Minibacterium massiliensis)
Length = 322
Score = 62.1 bits (144), Expect = 2e-08
Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 11/145 (7%)
Frame = +1
Query: 442 DDYISNAQDENFGIGY------DCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD---IAI 594
+D++++ +D + GY D P E V G + + A A
Sbjct: 73 EDFVTDVEDASPHRGYMPLDGGDTVMSPGSLEAVMRCVGAACAGVDLVLDNEAHNVFCAT 132
Query: 595 NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWTTR 768
CG HHA +RA GFC N IA K + + +D DVHHGNG Q A++
Sbjct: 133 RPCG--HHAEPSRAMGFCIYNQAAIAAAYAYEVHKLERVAVIDFDVHHGNGTQAAFYDRP 190
Query: 769 SVYTLSFHKFEPGFYPGTGSIEDIG 843
++ S H + FYPGTG ++ G
Sbjct: 191 ELFYASSH--QSHFYPGTGLEKETG 213
>UniRef50_A0G5H0 Cluster: Histone deacetylase superfamily; n=9;
Proteobacteria|Rep: Histone deacetylase superfamily -
Burkholderia phymatum STM815
Length = 315
Score = 62.1 bits (144), Expect = 2e-08
Identities = 41/125 (32%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Frame = +1
Query: 484 GYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIAD---IAINWCGGWHHAHNNRAEGFCYV 654
G D P +E V G + + G A A CG HHA ++A GFC
Sbjct: 82 GGDTVMSPGSWEAVMRCVGAACAGVDAVLAGEARNVFCATRPCG--HHAEPSKAMGFCIF 139
Query: 655 NDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGS 828
N IA K + + VD DVHHGNG Q A++ ++ S H + YPGTG
Sbjct: 140 NQAAIAAAYAYEVHKLERVAVVDFDVHHGNGTQAAFYNRPELFYASSH--QSPLYPGTGK 197
Query: 829 IEDIG 843
+ G
Sbjct: 198 AAETG 202
>UniRef50_A6ND61 Cluster: Uncharacterized protein HDAC8; n=3;
Simiiformes|Rep: Uncharacterized protein HDAC8 - Homo
sapiens (Human)
Length = 139
Score = 61.7 bits (143), Expect = 2e-08
Identities = 25/46 (54%), Positives = 33/46 (71%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQD 750
H + A GFCY+ND V+ I +L+ KF+ ILYVDLD+HHG+G D
Sbjct: 51 HKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGD 96
>UniRef50_Q9RW36 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=4; Deinococci|Rep: Histone
deacetylase/AcuC/AphA family protein - Deinococcus
radiodurans
Length = 301
Score = 61.3 bits (142), Expect = 3e-08
Identities = 43/128 (33%), Positives = 57/128 (44%), Gaps = 5/128 (3%)
Frame = +1
Query: 487 YDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVND-- 660
+ P P + AGGS+ A N GG HHA ++RAEGFC VND
Sbjct: 77 FGLPWSPEVVTRALRAAGGSLAALHDAQS--TGWGANLAGGTHHAFHDRAEGFCLVNDAA 134
Query: 661 IVIAIEKLKGKFKNILYVDLDVHHGNGVQDAY---WTTRSVYTLSFHKFEPGFYPGTGSI 831
I+ I +G + + +DLDVH GNG + +TLS H + S
Sbjct: 135 ILTRIALDRGLARRVATLDLDVHQGNGTASLLTPEMAAGTAFTLSIHGERNYPFRKERSS 194
Query: 832 EDIGCGDG 855
D+G GDG
Sbjct: 195 LDLGLGDG 202
>UniRef50_Q2SC27 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Hahella chejuensis KCTC 2396|Rep: Deacetylases,
including yeast histone deacetylase and acetoin
utilization protein - Hahella chejuensis (strain KCTC
2396)
Length = 318
Score = 60.9 bits (141), Expect = 4e-08
Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 7/100 (7%)
Frame = +1
Query: 541 GSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI-----EKLKGKFKNI 705
G++TAA A I N GG+HHA + EGFC+ +D +AI EK G +
Sbjct: 109 GTITAAHKAIEEEA-IVFNLGGGFHHAFRDHGEGFCFFSDAALAIQLLRAEKRLGSADEV 167
Query: 706 LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE--PGFYPG 819
L +DLD H GNG + + V+ + F+ PG + G
Sbjct: 168 LMIDLDAHRGNGFESYIASDPMVHNFDMYNFQAYPGLHQG 207
>UniRef50_A2BL29 Cluster: Predicted Histone deacetylase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Predicted Histone
deacetylase - Hyperthermus butylicus (strain DSM 5456 /
JCM 9403)
Length = 357
Score = 60.9 bits (141), Expect = 4e-08
Identities = 28/78 (35%), Positives = 39/78 (50%)
Frame = +1
Query: 640 GFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
GFC N +A + + +N+L VD D+HHGNG QD ++ + L H+ YPG
Sbjct: 143 GFCIFNISALAAKHAANRGENVLVVDFDLHHGNGTQDILYSDERIVHLDLHQDPSTIYPG 202
Query: 820 TGSIEDIGCGDGEGYSCN 873
TG + G G G N
Sbjct: 203 TGWPWENGSGRARGTKLN 220
>UniRef50_Q96DB2 Cluster: Histone deacetylase 11; n=22;
Eumetazoa|Rep: Histone deacetylase 11 - Homo sapiens
(Human)
Length = 347
Score = 60.9 bits (141), Expect = 4e-08
Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 3/180 (1%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
G+ V N ++ L+S ++ + AS EDL V H+ YL LK + I+
Sbjct: 40 GKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVAT--ITEIPP 97
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
F + + + T GG++ A K AIN GG+HH ++R GFC
Sbjct: 98 VIFLPNFLVQR--KVLRPLRTQTGGTIMAGKLAVE--RGWAINVGGGFHHCSSDRGGGFC 153
Query: 649 YVNDIVIAIEKLKGKFKNI---LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
DI +AI+ L + + I +DLD H GNG + + + VY + + YPG
Sbjct: 154 AYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDV--YNRHIYPG 211
>UniRef50_Q7NRU4 Cluster: Histone deacetylase; n=54;
Proteobacteria|Rep: Histone deacetylase -
Chromobacterium violaceum
Length = 319
Score = 60.5 bits (140), Expect = 6e-08
Identities = 48/183 (26%), Positives = 77/183 (42%), Gaps = 5/183 (2%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + + A + L+ I + SYE L H Y+E+L+
Sbjct: 38 RLTAIRDQLMASQIFDSLQEIEAPEVSYEQLARVHPPRYVEYLEACAP---------SVG 88
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCG---GWHHAHNNRAEG 642
F + D P + AG V A + + A A +C HHA +++A G
Sbjct: 89 TFRMDPDTAMSPGTLKAARRAAGAVVKAVELVAEDKAPNA--FCAIRPPGHHAESDKAMG 146
Query: 643 FCYVNDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
FC+ N++ + + KF+ + VD DVHHGNG ++ V +S F+ FYP
Sbjct: 147 FCFFNNLAVGVTHALAHYKFERVAVVDFDVHHGNGTEEILHDDPRVLMVSV--FQHPFYP 204
Query: 817 GTG 825
+G
Sbjct: 205 YSG 207
>UniRef50_A5WHG1 Cluster: Histone deacetylase superfamily; n=17;
Bacteria|Rep: Histone deacetylase superfamily -
Psychrobacter sp. PRwf-1
Length = 302
Score = 60.5 bits (140), Expect = 6e-08
Identities = 30/71 (42%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = +1
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYW 759
+++N GG HHA + EGFC ND+ IA L +G+ IL VDLDVH GNG
Sbjct: 110 VSLNVAGGTHHAFADHGEGFCVFNDVCIASNLLLSRGQASKILIVDLDVHQGNGNASIMA 169
Query: 760 TTRSVYTLSFH 792
V+ S H
Sbjct: 170 NEPRVFVFSMH 180
>UniRef50_Q7VZF1 Cluster: Histone deacetylase family protein; n=6;
Proteobacteria|Rep: Histone deacetylase family protein -
Bordetella pertussis
Length = 307
Score = 60.1 bits (139), Expect = 7e-08
Identities = 49/182 (26%), Positives = 79/182 (43%), Gaps = 3/182 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + + + A GL+ L+ ++ AS D+ H+ YL+ L+ +
Sbjct: 26 RLDAISDQLLASGLLPYLQERQAPEASRADILRVHTPAYLDSLRA---------HQPEHG 76
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI-NWCGGWHHAHNNRAEGFC 648
+ I D + +E AG V A + G A A + HHA + A GFC
Sbjct: 77 YYAIDADTSMNRHTYEAALRAAGAGVAAVDAVLGGEAITAFCSVRPPGHHAERDHAMGFC 136
Query: 649 YVNDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
++N++ IA + + VD DVHHGNG + A+ V SF F+ F+P +
Sbjct: 137 FLNNVAIAARHALDFHGLQRVALVDFDVHHGNGTEHAFAGDPRVLMCSF--FQHPFFPNS 194
Query: 823 GS 828
G+
Sbjct: 195 GA 196
>UniRef50_Q7U7V3 Cluster: Putative histone deacetylase/AcuC/AphA
family protein; n=4; Synechococcus|Rep: Putative histone
deacetylase/AcuC/AphA family protein - Synechococcus sp.
(strain WH8102)
Length = 323
Score = 60.1 bits (139), Expect = 7e-08
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 2/118 (1%)
Frame = +1
Query: 445 DYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAH 624
D +S ++ G+ P V + ++ G +TA L GIA + GG HHAH
Sbjct: 88 DQLSRSEQRRIGLPATRPLVQRTW---LSVGGTLLTARLALQHGIA---CHLAGGTHHAH 141
Query: 625 NNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
GFC ND+ L G+ + +L VDLDVH G+G + + TLS H
Sbjct: 142 PGFGSGFCIFNDVATTARVLLDNGEVQRLLVVDLDVHQGDGTAACFADEPRITTLSVH 199
>UniRef50_Q128P1 Cluster: Histone deacetylase superfamily; n=16;
Bacteria|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 337
Score = 59.7 bits (138), Expect = 1e-07
Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Frame = +1
Query: 496 PPVPNMFELVSTIAGGSVTAAK-CLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIV 666
P P M E AG +V AA+ L G +A N GG HHA+ ++ GFC ND
Sbjct: 102 PWSPGMAERARRSAGATVAAARVALGTGTRPQGVAANMAGGTHHAYAHKGSGFCVFNDSA 161
Query: 667 IAIEKLKGKF----------KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
+ ++ ++ + +DLDVH GNG + SV+TLS H
Sbjct: 162 VTARLMQAEWGRRHRPDRKPLQVAVIDLDVHQGNGTAHIFANDPSVFTLSLH 213
>UniRef50_Q586J9 Cluster: Histone deacetylase, putative; n=1;
Trypanosoma brucei|Rep: Histone deacetylase, putative -
Trypanosoma brucei
Length = 685
Score = 48.0 bits (109), Expect(2) = 1e-07
Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 2/141 (1%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
GR + + +E GL+ + + A +L + HS EH+ + ++ +
Sbjct: 144 GRLQRTLDHLEVIGLLECCRRLHHRSARTRELRLVHST---EHIDSVDQLEVATLLRKPG 200
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIA--DIAINWCGGWHHAHNNRAEG 642
E+ +G D N AG ++ AA + G A+ G HHA +RA G
Sbjct: 201 ESCNVGEDLYANENTSRAARAAAGCAIAAALSVVRGEVRNSFALIRPPG-HHAGRDRASG 259
Query: 643 FCYVNDIVIAIEKLKGKFKNI 705
FC+ N++ +A+ + + K +
Sbjct: 260 FCFFNNVAVAVRAAQRELKKL 280
Score = 31.1 bits (67), Expect(2) = 1e-07
Identities = 11/31 (35%), Positives = 20/31 (64%)
Frame = +1
Query: 703 ILYVDLDVHHGNGVQDAYWTTRSVYTLSFHK 795
+L +D DVHH +G ++ ++ SV +S H+
Sbjct: 308 VLVIDWDVHHCDGTENIFYEDPSVVVVSIHQ 338
>UniRef50_Q1VK67 Cluster: Histone deacetylase family protein; n=1;
Psychroflexus torquis ATCC 700755|Rep: Histone
deacetylase family protein - Psychroflexus torquis ATCC
700755
Length = 344
Score = 58.4 bits (135), Expect = 2e-07
Identities = 51/189 (26%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNL--IEAYGLISKLKVIRSSPASYEDLNVFHSDLYL 411
LW L + I A F R R L +E+ I +K+ E L++ H Y+
Sbjct: 27 LWYHPLYTDGIHPEARFPRDRYARLLKRLESKAPIGAIKIHEPKAVQSELLHLAHDQTYV 86
Query: 412 EHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIA 591
I ++ + +S +++ G+ P +M E + GG+V A + + +A
Sbjct: 87 -----IRFLNGE-MSASEERRIGLR---PWTSDMIERTLRLMGGAVEATEHAVLH-GGLA 136
Query: 592 INWCGGWHHAHNNRAEGFCYVNDI-VIAIEKLKG-KFKNILYVDLDVHHGNGVQDAYWTT 765
N GG HHAH G+C ND+ V A+ + + +DLDVH G+G
Sbjct: 137 GNMAGGTHHAHREFGSGYCVFNDLAVCALHAITSLGVGRVAVLDLDVHQGDGTASILAGE 196
Query: 766 RSVYTLSFH 792
+ V T+S H
Sbjct: 197 QRVLTVSAH 205
>UniRef50_Q3ZWU5 Cluster: Histone deacetylase family protein; n=3;
Dehalococcoides|Rep: Histone deacetylase family protein
- Dehalococcoides sp. (strain CBDB1)
Length = 341
Score = 58.0 bits (134), Expect = 3e-07
Identities = 48/187 (25%), Positives = 76/187 (40%), Gaps = 3/187 (1%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + +E +GL +L I +L FH Y+ ++++ ++ D+
Sbjct: 25 RLLAIMEYLETHGLKDRLVHIEPKRVGMRELESFHKRSYISRVEEVGFSGGGWL----DQ 80
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGG-WHHAHNNRAEGFC 648
+ I D +E GG + + D A C HHA + GFC
Sbjct: 81 DTVISLDS------YEAALYAVGGVIEGVDKVLSRELDSAFVLCRPPGHHALPEASMGFC 134
Query: 649 YVNDIVI-AIEKL-KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
N++ + A+ L K K K + VD DVHHGNG+Q + LS H+ +P T
Sbjct: 135 VFNNVALGALHALNKHKLKRVAVVDFDVHHGNGIQHVCLNDPRLIYLSLHQIH--HFPFT 192
Query: 823 GSIEDIG 843
G + G
Sbjct: 193 GDSRENG 199
>UniRef50_Q18477 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 282
Score = 58.0 bits (134), Expect = 3e-07
Identities = 40/97 (41%), Positives = 50/97 (51%), Gaps = 3/97 (3%)
Frame = +1
Query: 535 AGGSVTAAK-CLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNI 705
AGG+V AA L G A IN GG+HHA ++ GFC+ DI +AI L K N
Sbjct: 67 AGGTVLAANLALKHGWA---INVGGGFHHASHSGGGGFCFYADITMAIFDLFDKKAIANA 123
Query: 706 LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
+ VDLD H GNG + +V+ F F P YP
Sbjct: 124 IVVDLDAHQGNGHARDFADNPNVFV--FDVFNPYVYP 158
>UniRef50_Q944K3 Cluster: Histone deacetylase 2; n=7;
Magnoliophyta|Rep: Histone deacetylase 2 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 387
Score = 58.0 bits (134), Expect = 3e-07
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 2/165 (1%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
G + + ++ AS DL V HS+ YL LK + I+ F +
Sbjct: 111 GFLEEKAIVEPLEASKIDLLVVHSENYLNSLKSSATVAR--ITEVAPVAFFPNF-LVQQK 167
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIE--K 681
++ + GG++ AAK T AIN GG+HH R GFC DI + I
Sbjct: 168 VLYPFRKQV-GGTILAAKLATE--RGWAINIGGGFHHCTAERGGGFCAFADISLCIHFAF 224
Query: 682 LKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
L+ + ++ +DLD H GNG + VY L + P YP
Sbjct: 225 LRLRISRVMIIDLDAHQGNGHETDLGDDNRVYILDM--YNPEIYP 267
>UniRef50_Q31HC2 Cluster: Histone deacetylase family protein; n=1;
Thiomicrospira crunogena XCL-2|Rep: Histone deacetylase
family protein - Thiomicrospira crunogena (strain XCL-2)
Length = 306
Score = 57.6 bits (133), Expect = 4e-07
Identities = 39/115 (33%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Frame = +1
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIADIAI-NWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
P E +G +TA + A A N HHA NR GFC +N I I
Sbjct: 87 PGSLESALAASGAMLTAIDAIMHREAKQAFCNIRPPGHHAERNRPMGFCLINHIAIGAAY 146
Query: 682 LKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDI 840
K+ + I+ VD DVHHGNG +D V +S F+ G +P T I D+
Sbjct: 147 ALEKYALERIVIVDFDVHHGNGTEDYVRHEARVGYVS--SFQEGIFPFTDPISDL 199
>UniRef50_Q7RB89 Cluster: Histone deacetylase/AcuC/AphA family
protein, putative; n=6; Plasmodium|Rep: Histone
deacetylase/AcuC/AphA family protein, putative -
Plasmodium yoelii yoelii
Length = 461
Score = 57.6 bits (133), Expect = 4e-07
Identities = 25/65 (38%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
Frame = +1
Query: 604 GGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVY 777
GG HH+ ++ +GFC NDI IA++ L KN++ +D+DVH G+G + + ++V
Sbjct: 272 GGNHHSKRDKGDGFCIFNDIAIAVDFLLFYKIVKNVIILDVDVHQGDGTAEIFQNHQNVK 331
Query: 778 TLSFH 792
T+S H
Sbjct: 332 TISLH 336
>UniRef50_A5W9E9 Cluster: Histone deacetylase superfamily; n=17;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Pseudomonas putida F1
Length = 317
Score = 57.2 bits (132), Expect = 5e-07
Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 2/167 (1%)
Frame = +1
Query: 298 RLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENF 477
RL+H+ + GL + ++R + L + H Y+E + +S
Sbjct: 40 RLLHDHLVGSGLTTDQALLRPDICPNDILALAHDRSYIERYM------NGELSREDQRRL 93
Query: 478 GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVN 657
G+ + V + G +TA L GIA + GG HHAH + GFC N
Sbjct: 94 GLPWSEALARRT---VRAVGGSLLTAEMALQHGIA---CHLAGGTHHAHYDHPAGFCIFN 147
Query: 658 DIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
D+ + L G+ +L D DVH G+G T T+S H
Sbjct: 148 DLAVISRYLLEAGRVHRVLIFDCDVHQGDGTARILHDTPEAITVSLH 194
>UniRef50_A3EUN7 Cluster: Histone deacetylase family protein; n=1;
Leptospirillum sp. Group II UBA|Rep: Histone deacetylase
family protein - Leptospirillum sp. Group II UBA
Length = 236
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/93 (37%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA +RA GFC VN + + + +D DVHHGNG +D+ +S
Sbjct: 146 HHALRDRAMGFCLVNHTASLAQNIHQTDPDSRVAVLDFDVHHGNGTEDSLRGLDRCLFIS 205
Query: 787 FHKFEPGFYPGTGSIE-DIGCGDGEGYSCNFPL 882
H++ FYPGTGS E + DG G N PL
Sbjct: 206 THQYP--FYPGTGSEENNRSDADGSGV-LNLPL 235
>UniRef50_O27994 Cluster: Acetylpolyamine aminohydrolase, putative;
n=2; Euryarchaeota|Rep: Acetylpolyamine aminohydrolase,
putative - Archaeoglobus fulgidus
Length = 187
Score = 57.2 bits (132), Expect = 5e-07
Identities = 31/86 (36%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
Frame = +1
Query: 505 PNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL 684
P ++E+ GG++ A++ A AI G HHA + + GFCY N+I IA++KL
Sbjct: 7 PEIYEVAVLAVGGAILASEIAFNEPAFGAIRPPG--HHASPDSSWGFCYFNNIAIAVKKL 64
Query: 685 --KGKFKNILYVDLDVHHGNGVQDAY 756
+G+ K + VD D+H G+G +A+
Sbjct: 65 LVEGRIKKAVIVDFDLHFGDGTANAF 90
>UniRef50_A4C9H1 Cluster: Putative histone deacetylase family
protein; n=2; Pseudoalteromonas|Rep: Putative histone
deacetylase family protein - Pseudoalteromonas tunicata
D2
Length = 302
Score = 56.8 bits (131), Expect = 7e-07
Identities = 48/168 (28%), Positives = 68/168 (40%), Gaps = 2/168 (1%)
Frame = +1
Query: 295 ARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDEN 474
A L +L++ G ++ + + AS +L H YL L Q T +
Sbjct: 31 ADLYQHLVQT-GYVNH-NIFKPLRASISELEKVHCSRYLHQLNQNT------LDQKASRR 82
Query: 475 FGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYV 654
G+ + + F G +TA L GIA + GG HHAH + GFC V
Sbjct: 83 IGLPWSEQLMARTF---IEAQGTLLTAQLALKNGIA---CHLAGGTHHAHYDFGSGFCMV 136
Query: 655 NDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
ND+ L G N+L DLDVH G+G ++T S H
Sbjct: 137 NDLAYTAASLIDSGDVTNVLIFDLDVHQGDGTAAILQHHPYIFTCSIH 184
>UniRef50_A3W9J6 Cluster: Histone deacetylase superfamily protein;
n=1; Erythrobacter sp. NAP1|Rep: Histone deacetylase
superfamily protein - Erythrobacter sp. NAP1
Length = 369
Score = 56.8 bits (131), Expect = 7e-07
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDI-VIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSF 789
HH+ + G+CY+N+ ++A + + +D+D HHGNG QD ++ V+ S
Sbjct: 186 HHSGRDYYGGYCYLNNAAIVARAAVDRGLGPVAILDVDYHHGNGTQDIFYKDADVFFASI 245
Query: 790 HKFEPGFYP-GTGSIEDIGCGDGEGYSCNFPL 882
H YP G ++ G G GEG + N PL
Sbjct: 246 HADPASDYPYFWGHGDETGEGAGEGTTFNQPL 277
>UniRef50_A6VSZ5 Cluster: Histone deacetylase superfamily; n=4;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Marinomonas sp. MWYL1
Length = 307
Score = 56.4 bits (130), Expect = 9e-07
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 7/183 (3%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R + N + L+ L+ + S PA+ E L + H + Y +D + ++
Sbjct: 26 RLGAIQNRLIMGQLMDFLRRLESDPATREQLLLAHDEAY---------VDSIFARAPEEG 76
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCG---GWHHAHNNRAEG 642
+ + + +P+ + + A GSV A L M +++ +C HHA ++A G
Sbjct: 77 HVELEPETLMMPHTLD-AALYAAGSVIKAVDLVM-TSEMDNAFCAIRPPGHHAEYDKAMG 134
Query: 643 FCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSV-YTLSF-HKFEPGF 810
FC N+I + K+ + + VD DVHHGNG +D + V Y S+ H F P
Sbjct: 135 FCLFNNIAVGTRYAIEKYGLERVAIVDFDVHHGNGTEDIFKADPKVLYASSYQHPFYPYS 194
Query: 811 YPG 819
PG
Sbjct: 195 DPG 197
>UniRef50_Q00UC4 Cluster: Histone deacetylase superfamily; n=2;
Ostreococcus|Rep: Histone deacetylase superfamily -
Ostreococcus tauri
Length = 351
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +1
Query: 532 IAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNI 705
++G +T L G+A +N GG HHA R GFC +ND+ A + G+ +
Sbjct: 141 VSGTMLTVEMALECGLA---VNTAGGTHHAKGTRGGGFCILNDLATASLAVLNSGRLSRV 197
Query: 706 LYVDLDVHHGNGVQDAYWTT-RSVYTLSFH 792
+ VDLDVH G+G + YT S H
Sbjct: 198 MIVDLDVHQGDGTAEILENEWHRCYTFSAH 227
>UniRef50_Q7R8P2 Cluster: Histone deacetylase family, putative; n=1;
Plasmodium yoelii yoelii|Rep: Histone deacetylase
family, putative - Plasmodium yoelii yoelii
Length = 2009
Score = 56.4 bits (130), Expect = 9e-07
Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HH N GFC N+I +A + + K+ K I D DVHH NG Q+ ++ ++V S
Sbjct: 675 HHCSRNNPSGFCIFNNISVACKYIYIKYGIKKIFIFDWDVHHNNGTQEIFYNDKNVLCFS 734
Query: 787 FHKFE 801
H+F+
Sbjct: 735 IHRFD 739
>UniRef50_Q5C2D1 Cluster: SJCHGC03352 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03352 protein - Schistosoma
japonicum (Blood fluke)
Length = 175
Score = 56.4 bits (130), Expect = 9e-07
Identities = 30/96 (31%), Positives = 50/96 (52%), Gaps = 5/96 (5%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA ++R GFC+ N++ I + + + I +D DVHHGNG + ++ +S
Sbjct: 57 HHALSDRCMGFCFFNNVAIGARHAQQVYGLERIAIIDWDVHHGNGTAKIFEDDPNILYIS 116
Query: 787 FHKFEPG-FYPGT--GSIEDIGCGDGEGYSCNFPLN 885
H+F+ G ++P + S E G DG G + + N
Sbjct: 117 VHRFDNGRYFPNSNFSSGEFCGIDDGLGRTVHIAWN 152
>UniRef50_Q4YUE6 Cluster: Putative uncharacterized protein; n=3;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium berghei
Length = 1657
Score = 56.4 bits (130), Expect = 9e-07
Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HH N GFC N+I +A + + K+ K I D DVHH NG Q+ ++ ++V S
Sbjct: 416 HHCSRNNPSGFCIFNNISVACKYIYIKYGIKKIFIFDWDVHHNNGTQEIFYNDKNVLCFS 475
Query: 787 FHKFE 801
H+F+
Sbjct: 476 IHRFD 480
>UniRef50_A6C2D6 Cluster: Deacetylase; n=1; Planctomyces maris DSM
8797|Rep: Deacetylase - Planctomyces maris DSM 8797
Length = 319
Score = 55.6 bits (128), Expect = 2e-06
Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
Frame = +1
Query: 538 GGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK-----GKFKN 702
G V A + L G+A IN GG+HH+ + EGFC D IA+ L+ +
Sbjct: 108 GTIVAAQESLEHGLA---INLSGGYHHSKPAQGEGFCVYADAAIAVATLRQQALISETDR 164
Query: 703 ILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYP 816
I+YVD D H GNGV A+ + F F YP
Sbjct: 165 IVYVDTDAHQGNGVSHAFMNDNRAFL--FDIFNARAYP 200
>UniRef50_Q15WQ0 Cluster: Histone deacetylase superfamily; n=3;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 306
Score = 55.2 bits (127), Expect = 2e-06
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
Frame = +1
Query: 529 TIAGGSV-TAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFK 699
T GG+V T++ L G A +N GG+HHA N GFC ND+ +A + +
Sbjct: 100 TAVGGTVLTSSLALEHGKA---LNLTGGYHHAFANFGSGFCLFNDLYLAALNVLQTPTIR 156
Query: 700 NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDI 840
+L D DVH G+G + V+T+S H E F P + D+
Sbjct: 157 KVLIFDCDVHQGDGTAKLASNNKRVFTVSIHS-EKNF-PHRKQVSDL 201
>UniRef50_A0Y3M1 Cluster: Histone deacetylase family protein; n=1;
Alteromonadales bacterium TW-7|Rep: Histone deacetylase
family protein - Alteromonadales bacterium TW-7
Length = 299
Score = 55.2 bits (127), Expect = 2e-06
Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Frame = +1
Query: 538 GGSVTAAK-CLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKG--KFKNIL 708
GGS+ AA+ L G+ N GG+HHA+++ GFC ND+ IA L K K +L
Sbjct: 95 GGSIQAAEEALKSGLT---CNLSGGYHHAYSDYGSGFCIFNDLAIAATHLLSTHKAKTVL 151
Query: 709 YVDLDVHHGNGVQDA--YWTTRSVYTLSFH 792
D DVH G+G + +++ T S H
Sbjct: 152 IFDCDVHQGDGTAQIINQQSHKNIITCSIH 181
>UniRef50_Q1N4R7 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Oceanobacter sp. RED65|Rep: Deacetylases, including
yeast histone deacetylase and acetoin utilization
protein - Oceanobacter sp. RED65
Length = 308
Score = 54.8 bits (126), Expect = 3e-06
Identities = 45/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +1
Query: 304 VHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGI 483
V + GL + L + ++ P S E + HS Y++ L I+ +++
Sbjct: 31 VETKLRQSGLWNDLSIEQAKPVSREIFQLIHSKGYIDQLYNISPPKGMILADP------- 83
Query: 484 GYDCPPVPNMFELVSTIAGGSVTAAKCLTMGI---ADIAINWCGGWHHAHNNRAEGFCYV 654
D P + E AG + A + + G A AI G HHA + +GFC+V
Sbjct: 84 --DTPLAFDTLEATEEAAGSGIQAVESILSGKHQNAFCAIRPPG--HHAEPKKTKGFCFV 139
Query: 655 NDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGT 822
N+I +A + + +L D DVH NG +A+ V ++ F+ +YP +
Sbjct: 140 NNIALAAQHALNQAGINRVLIFDFDVHQANGTIEAFRGRDDVVVVT--SFQHPYYPNS 195
>UniRef50_Q1IMW0 Cluster: Histone deacetylase superfamily; n=2;
Acidobacteria|Rep: Histone deacetylase superfamily -
Acidobacteria bacterium (strain Ellin345)
Length = 298
Score = 54.8 bits (126), Expect = 3e-06
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Frame = +1
Query: 496 PPVPNMFELVSTIAGGSVTAAK-CLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIA 672
P P + + GG+++A L+ G GG HHA + G+C NDI IA
Sbjct: 80 PWSPELVKRTLGSVGGTLSAGMDALSSGFGGTL---AGGTHHAFRSEGSGYCVFNDIAIA 136
Query: 673 IEKL--KGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFH 792
I L KG + +DLDVH G+G + V T+S H
Sbjct: 137 ILYLRSKGLAQRAAVIDLDVHQGDGTAQIFQNDALVLTISVH 178
>UniRef50_A6GQW9 Cluster: Histone deacetylase family protein; n=1;
Limnobacter sp. MED105|Rep: Histone deacetylase family
protein - Limnobacter sp. MED105
Length = 306
Score = 54.8 bits (126), Expect = 3e-06
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA +RA GFC N++ IA + ++ +L VD DVHHGNG + A+ V S
Sbjct: 125 HHACVDRAMGFCVFNNVAIAAQHAIDAYRLERVLIVDFDVHHGNGTEHAFANNPKVLMCS 184
Query: 787 FHKFEPGFYPGTGSIE 834
F+ YP +G ++
Sbjct: 185 --TFQSPLYPFSGGLD 198
>UniRef50_A5K7A1 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 2206
Score = 54.8 bits (126), Expect = 3e-06
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKF--KNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HH N GFC N+I +A + + K+ + I D DVHH NG Q+ +++ + V S
Sbjct: 893 HHCSRNSPSGFCIFNNISVACKYIFKKYGIRKIFIFDWDVHHDNGTQEIFYSDKDVLCFS 952
Query: 787 FHKFE 801
H+F+
Sbjct: 953 IHRFD 957
>UniRef50_Q4CZ55 Cluster: Histone deacetylase, putative; n=2;
Trypanosoma cruzi|Rep: Histone deacetylase, putative -
Trypanosoma cruzi
Length = 661
Score = 54.0 bits (124), Expect = 5e-06
Identities = 41/182 (22%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
GR + + A GL+ + I A ++L + HS + H+ + ++ + +
Sbjct: 130 GRLKRTLEHLRAIGLLQCCRRISRHVARTKELRLVHS---IAHIDSVDQLEVAALLRHPE 186
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMG--IADIAINWCGGWHHAHNNRAEG 642
++ +G D + + G + AA + G + A+ G HHA N A G
Sbjct: 187 TSYSVGQDLYANTSTSKAARMAVGCVIAAALSVVRGEVMNAFALVRPPG-HHAGVNEASG 245
Query: 643 FCYVNDIVIAIEKLKGKFK-------NILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFE 801
FC+ N++ +A+ + + + L D DVHH +G + ++ SV +S H+
Sbjct: 246 FCFFNNVAVAVRVAQQELRQQGISAPRALVFDWDVHHCDGTESIFYEDPSVVVVSIHQHG 305
Query: 802 PG 807
G
Sbjct: 306 TG 307
>UniRef50_P72702 Cluster: Uncharacterized protein slr0245; n=15;
Cyanobacteria|Rep: Uncharacterized protein slr0245 -
Synechocystis sp. (strain PCC 6803)
Length = 304
Score = 54.0 bits (124), Expect = 5e-06
Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA N GFC +N++ IA + + + +D DVHHGNG + ++ S
Sbjct: 125 HHAIRNTGMGFCLLNNVAIAAHYALTRPGVERVAILDWDVHHGNGTEALVDHNPRIFYCS 184
Query: 787 FHKFEPGFYPGTGSIEDIGCGD 852
H+F YPGTG+ D G D
Sbjct: 185 LHQFP--CYPGTGAAGDRGQHD 204
>UniRef50_Q194I2 Cluster: Histone deacetylase superfamily; n=2;
Desulfitobacterium hafniense|Rep: Histone deacetylase
superfamily - Desulfitobacterium hafniense (strain
DCB-2)
Length = 441
Score = 53.6 bits (123), Expect = 6e-06
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Frame = +1
Query: 640 GFCYVNDIVIAIEKLKG--KFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFY 813
GFC +N+ I I L+ K + VD DVHHG+G QD ++ +V +S H+ Y
Sbjct: 118 GFCTLNNEAILINHLRTFHGIKKVAIVDTDVHHGDGTQDIFYHDPNVLFVSIHQDGRTLY 177
Query: 814 PGTGSIEDIGCGDGEGYSCNFPL 882
PG+G I + G + + + PL
Sbjct: 178 PGSGFIYEKGGPNAWETTLDIPL 200
>UniRef50_A6VZD7 Cluster: Histone deacetylase superfamily; n=2;
Marinomonas|Rep: Histone deacetylase superfamily -
Marinomonas sp. MWYL1
Length = 308
Score = 53.6 bits (123), Expect = 6e-06
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = +1
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKL--KGKFKNILYVDLDVHHGNGVQDAYW 759
+A + GG HHAH + GFC ND+ +A + G+ K IL +D DVH G+G +
Sbjct: 114 LACHLAGGTHHAHPSHGSGFCIFNDLAVAALAMIGSGRAKKILILDCDVHQGDGTIAFFK 173
Query: 760 TTRSVYTLSFH 792
+ +S+H
Sbjct: 174 DRVDIIPVSWH 184
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 841,816,313
Number of Sequences: 1657284
Number of extensions: 18021538
Number of successful extensions: 52437
Number of sequences better than 10.0: 309
Number of HSP's better than 10.0 without gapping: 47131
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51698
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 80751996367
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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